-- dump date 20140619_011539 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_697044.1 23500917 1165657 784..2274 1 NC_004310.3 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 2274 dnaA 1165657 dnaA Brucella suis 1330 chromosome replication initiator DnaA NP_697044.1 784 D 204722 CDS NP_697045.1 23500918 1165658 2503..3696 1 NC_004310.3 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3696 dnaN 1165658 dnaN Brucella suis 1330 DNA polymerase III subunit beta NP_697045.1 2503 D 204722 CDS NP_697046.1 23500919 1165659 3878..5032 1 NC_004310.3 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 5032 recF 1165659 recF Brucella suis 1330 recombination protein F NP_697046.1 3878 D 204722 CDS NP_697047.1 23500920 1165660 5070..5852 1 NC_004310.3 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 5852 moeB 1165660 moeB Brucella suis 1330 molybdopterin biosynthesis protein MoeB NP_697047.1 5070 D 204722 CDS NP_697048.1 23500921 1165661 complement(5869..6825) 1 NC_004310.3 identified by similarity to EGAD:90750; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase 6825 1165661 BR0005 Brucella suis 1330 D-isomer specific 2-hydroxyacid dehydrogenase NP_697048.1 5869 R 204722 CDS NP_697049.1 23500922 1165662 complement(6822..8447) 1 NC_004310.3 identified by similarity to SP:P33916; match to protein family HMM PF00005; ABC transporter ATP-binding protein 8447 1165662 BR0006 Brucella suis 1330 ABC transporter ATP-binding protein NP_697049.1 6822 R 204722 CDS NP_697050.1 23500923 1165663 complement(8471..9610) 1 NC_004310.3 identified by similarity to GP:17983985; match to protein family HMM PF00528; ABC transporter permease 9610 1165663 BR0007 Brucella suis 1330 ABC transporter permease NP_697050.1 8471 R 204722 CDS NP_697051.1 23500924 1165664 complement(9610..10707) 1 NC_004310.3 identified by similarity to SP:P33914; match to protein family HMM PF00528; ABC transporter permease 10707 1165664 BR0008 Brucella suis 1330 ABC transporter permease NP_697051.1 9610 R 204722 CDS NP_697052.1 23500925 1165665 complement(10819..12633) 1 NC_004310.3 identified by similarity to SP:P33913; match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein 12633 1165665 BR0009 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_697052.1 10819 R 204722 CDS NP_697053.1 23500926 1165666 complement(12680..14548) 1 NC_004310.3 identified by match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein 14548 1165666 BR0010 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_697053.1 12680 R 204722 CDS NP_697054.1 23500927 1165667 complement(14779..15102) 1 NC_004310.3 hypothetical protein 15102 1165667 BR0011 Brucella suis 1330 hypothetical protein NP_697054.1 14779 R 204722 CDS NP_697055.1 23500928 1165668 complement(15148..15348) 1 NC_004310.3 hypothetical protein 15348 1165668 BR0012 Brucella suis 1330 hypothetical protein NP_697055.1 15148 R 204722 CDS NP_697056.1 23500929 1165669 complement(15388..15738) 1 NC_004310.3 hypothetical protein 15738 1165669 BR0013 Brucella suis 1330 hypothetical protein NP_697056.1 15388 R 204722 CDS NP_697057.1 23500930 1165670 complement(16003..17109) 1 NC_004310.3 identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter perisplasmic amino acid-binding protein 17109 1165670 BR0014 Brucella suis 1330 branched-chain amino acid ABC transporter perisplasmic amino acid-binding protein NP_697057.1 16003 R 204722 CDS NP_697058.1 23500931 1165671 17381..17581 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1891; hypothetical protein 17581 1165671 BR0015 Brucella suis 1330 hypothetical protein NP_697058.1 17381 D 204722 CDS NP_697059.1 23500932 1165672 complement(17578..18372) 1 NC_004310.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 18372 1165672 BR0016 Brucella suis 1330 enoyl-CoA hydratase NP_697059.1 17578 R 204722 CDS NP_697060.1 23500933 1165674 complement(19224..21245) 1 NC_004310.3 identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; biotin carboxylase 21245 1165674 BR0018 Brucella suis 1330 biotin carboxylase NP_697060.1 19224 R 204722 CDS NP_697061.1 23500934 1165675 complement(21257..22864) 1 NC_004310.3 identified by match to protein family HMM PF01039; carboxyl transferase 22864 1165675 BR0019 Brucella suis 1330 carboxyl transferase NP_697061.1 21257 R 204722 CDS NP_697062.1 23500935 1165676 complement(22864..24012) 1 NC_004310.3 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; isovaleryl-CoA dehydrogenase 24012 ivd 1165676 ivd Brucella suis 1330 isovaleryl-CoA dehydrogenase NP_697062.1 22864 R 204722 CDS NP_697063.1 23500936 1165677 complement(24189..26177) 1 NC_004310.3 AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase 26177 1165677 BR0021 Brucella suis 1330 acetoacetyl-CoA synthetase NP_697063.1 24189 R 204722 CDS NP_697064.1 23500937 1165678 complement(26362..26796) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1269; hypothetical protein 26796 1165678 BR0022 Brucella suis 1330 hypothetical protein NP_697064.1 26362 R 204722 CDS NP_697065.1 23500938 1165679 complement(26973..28094) 1 NC_004310.3 identified by similarity to OMNI:CC1521; match to protein family HMM PF01757; hypothetical protein 28094 1165679 BR0023 Brucella suis 1330 hypothetical protein NP_697065.1 26973 R 204722 CDS NP_697066.1 23500939 1165681 complement(28617..29000) 1 NC_004310.3 identified by similarity to GP:15073181; hypothetical protein 29000 1165681 BR0024 Brucella suis 1330 hypothetical protein NP_697066.1 28617 R 204722 CDS NP_697067.1 23500940 1165682 29385..30737 1 NC_004310.3 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 30737 aroA 1165682 aroA Brucella suis 1330 3-phosphoshikimate 1-carboxyvinyltransferase NP_697067.1 29385 D 204722 CDS NP_697068.1 23500941 1165683 30734..31393 1 NC_004310.3 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 31393 cmk 1165683 cmk Brucella suis 1330 cytidylate kinase NP_697068.1 30734 D 204722 CDS NP_697069.1 23500942 1165684 31609..33309 1 NC_004310.3 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 33309 rpsA 1165684 rpsA Brucella suis 1330 30S ribosomal protein S1 NP_697069.1 31609 D 204722 CDS NP_697070.1 23500943 1165685 complement(33727..34737) 1 NC_004310.3 identified by similarity to GP:15155628; match to protein family HMM PF03601; hypothetical protein 34737 1165685 BR0028 Brucella suis 1330 hypothetical protein NP_697070.1 33727 R 204722 CDS NP_697071.1 23500944 1165686 34853..35752 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 35752 1165686 BR0029 Brucella suis 1330 LysR family transcriptional regulator NP_697071.1 34853 D 204722 CDS NP_697072.1 23500945 1165687 complement(35746..36321) 1 NC_004310.3 hypothetical protein 36321 1165687 BR0030 Brucella suis 1330 hypothetical protein NP_697072.1 35746 R 204722 CDS NP_697073.1 23500946 1165688 complement(36357..37640) 1 NC_004310.3 transglycosylase 37640 1165688 BR0031 Brucella suis 1330 transglycosylase NP_697073.1 36357 R 204722 CDS NP_697074.1 23500947 1165689 complement(37656..38261) 1 NC_004310.3 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 38261 recR 1165689 recR Brucella suis 1330 recombination protein RecR NP_697074.1 37656 R 204722 CDS NP_697075.1 23500948 1165690 complement(38392..38715) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4268; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein 38715 1165690 BR0033 Brucella suis 1330 hypothetical protein NP_697075.1 38392 R 204722 CDS NP_697076.1 23500949 1165691 complement(38740..40548) 1 NC_004310.3 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 40548 dnaX 1165691 dnaX Brucella suis 1330 DNA polymerase III subunits gamma and tau NP_697076.1 38740 R 204722 CDS NP_697077.1 23500950 1165692 40829..41233 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4266; match to protein family HMM PF01230; hypothetical protein 41233 1165692 BR0035 Brucella suis 1330 hypothetical protein NP_697077.1 40829 D 204722 CDS NP_697078.1 23500951 1165693 41262..42209 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4265; match to protein family HMM PF00293; MutT/nudix family protein 42209 1165693 BR0036 Brucella suis 1330 MutT/nudix family protein NP_697078.1 41262 D 204722 CDS NP_697079.1 23500952 1165694 complement(42210..43073) 1 NC_004310.3 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 43073 pheA 1165694 pheA Brucella suis 1330 prephenate dehydratase NP_697079.1 42210 R 204722 CDS NP_697080.1 23500953 1165695 complement(43162..43917) 1 NC_004310.3 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase 43917 kdsB 1165695 kdsB Brucella suis 1330 3-deoxy-manno-octulosonate cytidylyltransferase NP_697080.1 43162 R 204722 CDS NP_697081.1 23500954 1165696 44295..44903 1 NC_004310.3 identified by similarity to EGAD:14195; match to protein family HMM PF00034; cytochrome c, membrane-bound 44903 1165696 BR0039 Brucella suis 1330 cytochrome c, membrane-bound NP_697081.1 44295 D 204722 CDS NP_697082.1 23500955 1165697 complement(44948..45913) 1 NC_004310.3 identified by similarity to GP:14021137; match to protein family HMM PF00994; hypothetical protein 45913 1165697 BR0040 Brucella suis 1330 hypothetical protein NP_697082.1 44948 R 204722 CDS NP_697083.1 23500956 1165698 45969..46277 1 NC_004310.3 hypothetical protein 46277 1165698 BR0041 Brucella suis 1330 hypothetical protein NP_697083.1 45969 D 204722 CDS NP_697084.1 23500957 1165699 46440..47465 1 NC_004310.3 identified by similarity to EGAD:20044; match to protein family HMM TIGR01433; ubiquinol oxidase subunit II 47465 cyoA 1165699 cyoA Brucella suis 1330 ubiquinol oxidase subunit II NP_697084.1 46440 D 204722 CDS NP_697085.1 23500958 1165700 47545..49524 1 NC_004310.3 identified by similarity to EGAD:14783; match to protein family HMM PF00115; ubiquinol oxidase subunit I 49524 qoxB 1165700 qoxB Brucella suis 1330 ubiquinol oxidase subunit I NP_697085.1 47545 D 204722 CDS NP_697086.1 23500959 1165701 49528..50157 1 NC_004310.3 identified by similarity to EGAD:13682; match to protein family HMM PF00510; ubiquinol oxidase subunit III 50157 1165701 BR0044 Brucella suis 1330 ubiquinol oxidase subunit III NP_697086.1 49528 D 204722 CDS NP_697087.1 23500960 1165702 50157..50522 1 NC_004310.3 identified by similarity to EGAD:20825; match to protein family HMM PF03626; ubiquinol oxidase subunit IV 50522 qoxD 1165702 qoxD Brucella suis 1330 ubiquinol oxidase subunit IV NP_697087.1 50157 D 204722 CDS NP_697088.1 23500961 1165703 complement(50519..50797) 1 NC_004310.3 hypothetical protein 50797 1165703 BR0046 Brucella suis 1330 hypothetical protein NP_697088.1 50519 R 204722 CDS NP_697089.1 23500962 1165704 50973..51560 1 NC_004310.3 identified by similarity to GP:3511221; hypothetical protein 51560 1165704 BR0047 Brucella suis 1330 hypothetical protein NP_697089.1 50973 D 204722 CDS NP_697090.1 23500963 1165705 52156..54075 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1304; match to protein family HMM PF01103; hypothetical protein 54075 1165705 BR0048 Brucella suis 1330 hypothetical protein NP_697090.1 52156 D 204722 CDS NP_697091.1 23500964 1165706 54264..58811 1 NC_004310.3 identified by similarity to GP:15076022; match to protein family HMM PF04357; match to protein family HMM TIGR01612; hypothetical protein 58811 1165706 BR0049 Brucella suis 1330 hypothetical protein NP_697091.1 54264 D 204722 CDS NP_697092.1 23500965 1165707 58956..59681 1 NC_004310.3 identified by similarity to GP:15160041; match to protein family HMM PF03734; match to protein family HMM TIGR01409; lipoprotein 59681 1165707 BR0050 Brucella suis 1330 lipoprotein NP_697092.1 58956 D 204722 CDS NP_697093.1 23500966 1165708 complement(59732..59947) 1 NC_004310.3 hypothetical protein 59947 1165708 BR0051 Brucella suis 1330 hypothetical protein NP_697093.1 59732 R 204722 CDS NP_697094.1 23500967 1165709 complement(60017..60520) 1 NC_004310.3 hypothetical protein 60520 1165709 BR0052 Brucella suis 1330 hypothetical protein NP_697094.1 60017 R 204722 CDS NP_697095.1 23500968 1165710 complement(60857..61063) 1 NC_004310.3 hypothetical protein 61063 1165710 BR0053 Brucella suis 1330 hypothetical protein NP_697095.1 60857 R 204722 CDS NP_697096.1 23500969 1165711 complement(61074..62078) 1 NC_004310.3 identified by similarity to GP:15074483; match to protein family HMM PF04314; hypothetical protein 62078 1165711 BR0054 Brucella suis 1330 hypothetical protein NP_697096.1 61074 R 204722 CDS NP_697097.1 23500970 1165712 complement(62213..62611) 1 NC_004310.3 hypothetical protein 62611 1165712 BR0055 Brucella suis 1330 hypothetical protein NP_697097.1 62213 R 204722 CDS NP_697098.1 23500971 1165713 complement(62864..63259) 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 63259 1165713 BR0056 Brucella suis 1330 glyoxalase NP_697098.1 62864 R 204722 CDS NP_697099.1 23500972 1165714 63456..64619 1 NC_004310.3 identified by match to protein family HMM PF01883; mrp-like protein 64619 1165714 BR0057 Brucella suis 1330 mrp-like protein NP_697099.1 63456 D 204722 CDS NP_697100.1 23500973 1165715 complement(64824..66455) 1 NC_004310.3 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase 66455 pgm 1165715 pgm Brucella suis 1330 phosphoglucomutase NP_697100.1 64824 R 204722 CDS NP_697101.1 23500974 1165716 complement(66511..66696) 1 NC_004310.3 hypothetical protein 66696 1165716 BR0059 Brucella suis 1330 hypothetical protein NP_697101.1 66511 R 204722 CDS NP_697102.1 23500975 1165717 complement(66671..67564) 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 67564 1165717 BR0060 Brucella suis 1330 LysR family transcriptional regulator NP_697102.1 66671 R 204722 CDS NP_697103.1 23500976 1165718 67689..68612 1 NC_004310.3 dienelactone hydrolase domain-containing protein 68612 1165718 BR0061 Brucella suis 1330 dienelactone hydrolase domain-containing protein NP_697103.1 67689 D 204722 CDS NP_697104.1 23500977 1165719 68685..69383 1 NC_004310.3 identified by similarity to GP:11066210; fructose transport system kinase 69383 frcK 1165719 frcK Brucella suis 1330 fructose transport system kinase NP_697104.1 68685 D 204722 CDS NP_697105.1 23500978 1165720 69483..70172 1 NC_004310.3 identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase 70172 1165720 BR0063 Brucella suis 1330 fumarylacetoacetate hydrolase NP_697105.1 69483 D 204722 CDS NP_697106.1 23500979 1165721 70192..70383 1 NC_004310.3 identified by similarity to GP:15073555; hypothetical protein 70383 1165721 BR0064 Brucella suis 1330 hypothetical protein NP_697106.1 70192 D 204722 CDS NP_697107.1 23500980 1165722 70445..70660 1 NC_004310.3 hypothetical protein 70660 1165722 BR0065 Brucella suis 1330 hypothetical protein NP_697107.1 70445 D 204722 CDS NP_697108.1 23500981 1165723 70826..71014 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3554; hypothetical protein 71014 1165723 BR0066 Brucella suis 1330 hypothetical protein NP_697108.1 70826 D 204722 CDS NP_697109.1 23500982 1165724 71029..71892 1 NC_004310.3 identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 71892 1165724 BR0067 Brucella suis 1330 transglycosylase SLT domain-containing protein NP_697109.1 71029 D 204722 CDS NP_697110.1 23500983 1165725 72078..72734 1 NC_004310.3 identified by similarity to EGAD:38000; match to protein family HMM PF03006; hemolysin III family channel protein 72734 1165725 BR0068 Brucella suis 1330 hemolysin III family channel protein NP_697110.1 72078 D 204722 CDS NP_697111.1 23500984 1165726 complement(72875..76108) 1 NC_004310.3 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase 76108 dnaE2 1165726 dnaE2 Brucella suis 1330 error-prone DNA polymerase NP_697111.1 72875 R 204722 CDS NP_697112.1 23500985 1165727 complement(76108..77559) 1 NC_004310.3 identified by similarity to GP:14523587; hypothetical protein 77559 1165727 BR0070 Brucella suis 1330 hypothetical protein NP_697112.1 76108 R 204722 CDS NP_697113.1 23500986 1165728 complement(77585..78448) 1 NC_004310.3 identified by similarity to GP:15076199; hypothetical protein 78448 1165728 BR0071 Brucella suis 1330 hypothetical protein NP_697113.1 77585 R 204722 CDS NP_697114.1 23500987 1165729 78967..81189 1 NC_004310.3 identified by similarity to SP:P10858; match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; hypothetical protein 81189 1165729 BR0072 Brucella suis 1330 hypothetical protein NP_697114.1 78967 D 204722 CDS NP_697115.1 23500988 1165730 81398..81946 1 NC_004310.3 identified by similarity to GP:15073388; hypothetical protein 81946 1165730 BR0073 Brucella suis 1330 hypothetical protein NP_697115.1 81398 D 204722 CDS NP_697116.1 23500989 1165731 complement(82025..83245) 1 NC_004310.3 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 83245 argG 1165731 argG Brucella suis 1330 argininosuccinate synthase NP_697116.1 82025 R 204722 CDS NP_697117.1 23500990 1165733 complement(84095..84598) 1 NC_004310.3 hypothetical protein 84598 1165733 BR0076 Brucella suis 1330 hypothetical protein NP_697117.1 84095 R 204722 CDS NP_697118.1 23500991 1165734 complement(84632..85867) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3355; match to protein family HMM PF04055; match to protein family HMM TIGR00048; hypothetical protein 85867 1165734 BR0077 Brucella suis 1330 hypothetical protein NP_697118.1 84632 R 204722 CDS NP_697119.1 23500992 1165735 85811..86002 1 NC_004310.3 hypothetical protein 86002 1165735 BR0078 Brucella suis 1330 hypothetical protein NP_697119.1 85811 D 204722 CDS NP_697120.1 23500993 1165736 85987..86181 1 NC_004310.3 hypothetical protein 86181 1165736 BR0079 Brucella suis 1330 hypothetical protein NP_697120.1 85987 D 204722 CDS NP_697121.1 23500994 1165737 complement(86127..86630) 1 NC_004310.3 identified by similarity to GP:15076241; hypothetical protein 86630 1165737 BR0080 Brucella suis 1330 hypothetical protein NP_697121.1 86127 R 204722 CDS NP_697122.1 23500995 1165738 complement(87070..87453) 1 NC_004310.3 identified by similarity to GP:15076242; hypothetical protein 87453 1165738 BR0081 Brucella suis 1330 hypothetical protein NP_697122.1 87070 R 204722 CDS NP_697123.1 23500996 1165739 complement(87541..87834) 1 NC_004310.3 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase 87834 phhB 1165739 phhB Brucella suis 1330 pterin-4-alpha-carbinolamine dehydratase NP_697123.1 87541 R 204722 CDS NP_697124.1 23500997 1165740 88061..88666 1 NC_004310.3 identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 88666 1165740 BR0083 Brucella suis 1330 phosphotyrosine protein phosphatase NP_697124.1 88061 D 204722 CDS NP_697125.1 23500998 1165741 complement(88576..89166) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3347; hypothetical protein 89166 1165741 BR0084 Brucella suis 1330 hypothetical protein NP_697125.1 88576 R 204722 CDS NP_697126.1 23500999 1165742 complement(89347..90072) 1 NC_004310.3 identified by match to protein family HMM PF00657; lipase/acylhydrolase domain-containing protein 90072 1165742 BR0085 Brucella suis 1330 lipase/acylhydrolase domain-containing protein NP_697126.1 89347 R 204722 CDS NP_697127.1 23501000 1165743 90219..90947 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 90947 1165743 BR0086 Brucella suis 1330 ABC transporter ATP-binding protein NP_697127.1 90219 D 204722 CDS NP_697128.1 23501001 1165744 90944..93493 1 NC_004310.3 identified by match to protein family HMM PF02687; ABC transporter permease 93493 1165744 BR0087 Brucella suis 1330 ABC transporter permease NP_697128.1 90944 D 204722 CDS NP_697129.1 23501002 1165745 93727..94464 1 NC_004310.3 identified by similarity to GP:15076248; match to protein family HMM PF01027; hypothetical protein 94464 1165745 BR0088 Brucella suis 1330 hypothetical protein NP_697129.1 93727 D 204722 CDS NP_697130.1 23501003 1165746 94579..95118 1 NC_004310.3 identified by similarity to EGAD:8993; match to protein family HMM PF00583; phosphinothricin N-acetyltransferase 95118 pat 1165746 pat Brucella suis 1330 phosphinothricin N-acetyltransferase NP_697130.1 94579 D 204722 CDS NP_697131.1 23501004 1165747 complement(95138..95539) 1 NC_004310.3 identified by similarity to GP:15076253; hypothetical protein 95539 1165747 BR0090 Brucella suis 1330 hypothetical protein NP_697131.1 95138 R 204722 CDS NP_697132.1 23501005 1165748 complement(96089..96823) 1 NC_004310.3 identified by similarity to GP:15076254; hypothetical protein 96823 1165748 BR0091 Brucella suis 1330 hypothetical protein NP_697132.1 96089 R 204722 CDS NP_697133.1 23501006 1165749 complement(96976..97116) 1 NC_004310.3 hypothetical protein 97116 1165749 BR0092 Brucella suis 1330 hypothetical protein NP_697133.1 96976 R 204722 CDS NP_697134.1 23501007 1165750 complement(97100..99787) 1 NC_004310.3 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 99787 acnA 1165750 acnA Brucella suis 1330 aconitate hydratase NP_697134.1 97100 R 204722 CDS NP_697135.1 23501008 1165751 100131..100778 1 NC_004310.3 ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 100778 ccmA 1165751 ccmA Brucella suis 1330 cytochrome c biogenesis protein CcmA NP_697135.1 100131 D 204722 CDS NP_697136.1 23501009 1165752 100778..101443 1 NC_004310.3 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB 101443 ccmB 1165752 ccmB Brucella suis 1330 heme exporter protein CcmB NP_697136.1 100778 D 204722 CDS NP_697137.1 23501010 1165753 101501..102286 1 NC_004310.3 identified by similarity to SP:P30962; match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein CcmC 102286 ccmC 1165753 ccmC Brucella suis 1330 heme exporter protein CcmC NP_697137.1 101501 D 204722 CDS NP_697138.1 23501011 1165754 102283..102456 1 NC_004310.3 identified by similarity to EGAD:15659; match to protein family HMM PF04995; heme exporter protein D 102456 1165754 BR0097 Brucella suis 1330 heme exporter protein D NP_697138.1 102283 D 204722 CDS NP_697139.1 23501012 1165755 102453..103064 1 NC_004310.3 identified by match to protein family HMM TIGR00385; thioredoxin 103064 cycY 1165755 cycY Brucella suis 1330 thioredoxin NP_697139.1 102453 D 204722 CDS NP_697140.1 23501013 1165756 complement(103313..105148) 1 NC_004310.3 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 105148 ilvD 1165756 ilvD Brucella suis 1330 dihydroxy-acid dehydratase NP_697140.1 103313 R 204722 CDS NP_697141.1 23501014 1165757 105330..105467 1 NC_004310.3 hypothetical protein 105467 1165757 BR0100 Brucella suis 1330 hypothetical protein NP_697141.1 105330 D 204722 CDS NP_697142.1 23501015 1165758 complement(105548..105901) 1 NC_004310.3 identified by similarity to GP:15157523; hypothetical protein 105901 1165758 BR0101 Brucella suis 1330 hypothetical protein NP_697142.1 105548 R 204722 CDS NP_697143.1 23501016 1165759 complement(106006..106383) 1 NC_004310.3 identified by similarity to OMNI:CC3015; match to protein family HMM PF00072; response regulator 106383 1165759 BR0102 Brucella suis 1330 response regulator NP_697143.1 106006 R 204722 CDS NP_697144.1 23501017 1165760 complement(106558..106794) 1 NC_004310.3 transcriptional regulator 106794 1165760 BR0103 Brucella suis 1330 transcriptional regulator NP_697144.1 106558 R 204722 CDS NP_697145.1 23501018 1165761 107447..107851 1 NC_004310.3 identified by similarity to GP:15155891; hypothetical protein 107851 1165761 BR0104 Brucella suis 1330 hypothetical protein NP_697145.1 107447 D 204722 CDS NP_697146.1 23501019 1165762 complement(107937..108641) 1 NC_004310.3 hypothetical protein 108641 1165762 BR0105 Brucella suis 1330 hypothetical protein NP_697146.1 107937 R 204722 CDS NP_697147.1 23501020 1165763 108713..109531 1 NC_004310.3 identified by similarity to EGAD:8060; hypothetical protein 109531 1165763 BR0106 Brucella suis 1330 hypothetical protein NP_697147.1 108713 D 204722 CDS NP_697148.1 23501021 1165764 109809..110837 1 NC_004310.3 identified by similarity to GP:17983880; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter sulfate-binding protein 110837 1165764 BR0107 Brucella suis 1330 sulfate ABC transporter sulfate-binding protein NP_697148.1 109809 D 204722 CDS NP_697149.1 23501022 1165765 110932..111798 1 NC_004310.3 identified by similarity to SP:Q01895; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease 111798 1165765 BR0108 Brucella suis 1330 sulfate ABC transporter permease NP_697149.1 110932 D 204722 CDS NP_697150.1 23501023 1165766 111788..112654 1 NC_004310.3 identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease 112654 cysW-1 1165766 cysW-1 Brucella suis 1330 sulfate ABC transporter permease NP_697150.1 111788 D 204722 CDS NP_697151.1 23501024 1165767 112752..113831 1 NC_004310.3 identified by similarity to SP:P14788; match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate ABC transporter ATP-binding protein 113831 1165767 BR0110 Brucella suis 1330 sulfate ABC transporter ATP-binding protein NP_697151.1 112752 D 204722 CDS NP_697152.1 23501025 1165768 114622..122820 1 NC_004310.3 identified by similarity to GP:3551791; match to protein family HMM TIGR01612; cyclic beta 1-2 glucan synthetase 122820 1165768 BR0111 Brucella suis 1330 cyclic beta 1-2 glucan synthetase NP_697152.1 114622 D 204722 CDS NP_697153.1 23501026 1165769 122910..124214 1 NC_004310.3 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 124214 pncB 1165769 pncB Brucella suis 1330 nicotinate phosphoribosyltransferase NP_697153.1 122910 D 204722 CDS NP_697154.1 23501027 1165770 complement(124256..125086) 1 NC_004310.3 identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein 125086 1165770 BR0113 Brucella suis 1330 PhzF family phenazine biosynthesis protein NP_697154.1 124256 R 204722 CDS NP_697155.1 23501028 1165771 complement(125196..125984) 1 NC_004310.3 identified by similarity to GP:15075131; hypothetical protein 125984 1165771 BR0114 Brucella suis 1330 hypothetical protein NP_697155.1 125196 R 204722 CDS NP_697156.1 23501029 1165772 complement(126007..126933) 1 NC_004310.3 identified by similarity to EGAD:15614; match to protein family HMM PF00294; fructokinase 126933 cscK 1165772 cscK Brucella suis 1330 fructokinase NP_697156.1 126007 R 204722 CDS NP_697157.1 23501030 1165773 complement(127024..127830) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 127830 1165773 BR0116 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_697157.1 127024 R 204722 CDS NP_697158.1 23501031 1165774 complement(127951..130242) 1 NC_004310.3 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein 130242 1165774 BR0117 Brucella suis 1330 1A family penicillin-binding protein NP_697158.1 127951 R 204722 CDS NP_697159.1 23501032 1165775 complement(130447..131139) 1 NC_004310.3 hypothetical protein 131139 1165775 BR0118 Brucella suis 1330 hypothetical protein NP_697159.1 130447 R 204722 CDS NP_697160.1 23501033 1165776 complement(131407..132093) 1 NC_004310.3 identified by similarity to EGAD:151783; hypothetical protein 132093 1165776 BR0119 Brucella suis 1330 hypothetical protein NP_697160.1 131407 R 204722 CDS NP_697161.1 23501034 1165777 complement(132325..132942) 1 NC_004310.3 identified by match to protein family HMM PF01612; 3'-5' exonuclease 132942 1165777 BR0120 Brucella suis 1330 3'-5' exonuclease NP_697161.1 132325 R 204722 CDS NP_697162.1 23501035 1165778 complement(132981..134396) 1 NC_004310.3 identified by match to protein family HMM PF01546; hypothetical protein 134396 1165778 BR0121 Brucella suis 1330 hypothetical protein NP_697162.1 132981 R 204722 CDS NP_697163.1 23501036 1165779 134549..134875 1 NC_004310.3 hypothetical protein 134875 1165779 BR0122 Brucella suis 1330 hypothetical protein NP_697163.1 134549 D 204722 CDS NP_697164.1 23501037 1165780 134957..137896 1 NC_004310.3 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 137896 polA 1165780 polA Brucella suis 1330 DNA polymerase I NP_697164.1 134957 D 204722 CDS NP_697165.1 23501038 1165781 138038..139918 1 NC_004310.3 identified by similarity to SP:P23304; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; DEAD-box ATP dependent DNA helicase 139918 1165781 BR0124 Brucella suis 1330 DEAD-box ATP dependent DNA helicase NP_697165.1 138038 D 204722 CDS NP_697166.1 23501039 1165782 complement(140014..142446) 1 NC_004310.3 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 142446 gyrB 1165782 gyrB Brucella suis 1330 DNA gyrase subunit B NP_697166.1 140014 R 204722 CDS NP_697167.1 23501040 1165783 complement(142506..142673) 1 NC_004310.3 hypothetical protein 142673 1165783 BR0126 Brucella suis 1330 hypothetical protein NP_697167.1 142506 R 204722 CDS NP_697168.1 23501041 1165784 complement(142777..143532) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5595; match to protein family HMM PF00756; esterase 143532 1165784 BR0127 Brucella suis 1330 esterase NP_697168.1 142777 R 204722 CDS NP_697169.1 23501042 1165785 complement(143621..144277) 1 NC_004310.3 identified by similarity to GP:14021760; hypothetical protein 144277 1165785 BR0128 Brucella suis 1330 hypothetical protein NP_697169.1 143621 R 204722 CDS NP_697170.1 23501043 1165786 complement(144277..144744) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 144744 1165786 BR0129 Brucella suis 1330 acetyltransferase NP_697170.1 144277 R 204722 CDS NP_697171.1 23501044 1165788 complement(145890..146174) 1 NC_004310.3 identified by similarity to EGAD:97446; match to protein family HMM PF02583; hypothetical protein 146174 1165788 BR0131 Brucella suis 1330 hypothetical protein NP_697171.1 145890 R 204722 CDS NP_697172.1 23501045 1165790 148850..150142 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 150142 1165790 BR0133 Brucella suis 1330 sensor histidine kinase NP_697172.1 148850 D 204722 CDS NP_697173.1 23501046 1165791 150234..150545 1 NC_004310.3 identified by similarity to EGAD:46813; IS711, transposase orfA 150545 1165791 BR0134 Brucella suis 1330 IS711, transposase orfA NP_697173.1 150234 D 204722 CDS NP_697174.1 23501047 1165792 150577..150969 1 NC_004310.3 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 150969 1165792 BR0135 Brucella suis 1330 IS711, transposase orfB NP_697174.1 150577 D 204722 CDS NP_697175.1 23501048 1165793 151035..151373 1 NC_004310.3 hypothetical protein 151373 1165793 BR0136 Brucella suis 1330 hypothetical protein NP_697175.1 151035 D 204722 CDS NP_697176.1 23501049 1165794 151569..152132 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM TIGR01199; DNA-binding response regulator 152132 1165794 BR0137 Brucella suis 1330 DNA-binding response regulator NP_697176.1 151569 D 204722 CDS NP_697177.1 23501050 1165795 complement(152138..152632) 1 NC_004310.3 identified by similarity to GP:15154914; hypothetical protein 152632 1165795 BR0138 Brucella suis 1330 hypothetical protein NP_697177.1 152138 R 204722 CDS NP_697178.1 23501051 1165796 152901..153521 1 NC_004310.3 identified by similarity to GP:9392598; match to protein family HMM PF03734; lipoprotein 153521 1165796 BR0139 Brucella suis 1330 lipoprotein NP_697178.1 152901 D 204722 CDS NP_697179.1 23501052 1165797 complement(153611..154183) 1 NC_004310.3 identified by match to protein family HMM PF01106; NifU-like protein 154183 1165797 BR0140 Brucella suis 1330 NifU-like protein NP_697179.1 153611 R 204722 CDS NP_697180.1 23501053 1165798 complement(154292..154780) 1 NC_004310.3 identified by similarity to GP:15155260; match to protein family HMM PF00582; hypothetical protein 154780 1165798 BR0141 Brucella suis 1330 hypothetical protein NP_697180.1 154292 R 204722 CDS NP_697181.2 161486701 1165799 complement(154838..155905) 1 NC_004310.3 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 155905 trpS 1165799 trpS Brucella suis 1330 tryptophanyl-tRNA synthetase NP_697181.2 154838 R 204722 CDS NP_697182.1 23501055 1165800 complement(156002..157591) 1 NC_004310.3 identified by similarity to SP:P56882; match to protein family HMM PF03023; match to protein family HMM TIGR01695; virulence factor MviN 157591 mviN 1165800 mviN Brucella suis 1330 virulence factor MviN NP_697182.1 156002 R 204722 CDS NP_697183.1 23501056 1165801 complement(157605..160409) 1 NC_004310.3 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase 160409 1165801 BR0144 Brucella suis 1330 PII uridylyl-transferase NP_697183.1 157605 R 204722 CDS NP_697184.1 23501057 1165802 160475..160570 1 NC_004310.3 hypothetical protein 160570 1165802 BR0145 Brucella suis 1330 hypothetical protein NP_697184.1 160475 D 204722 CDS NP_697185.1 23501058 1165804 162981..165713 1 NC_004310.3 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 165713 mutS 1165804 mutS Brucella suis 1330 DNA mismatch repair protein MutS NP_697185.1 162981 D 204722 CDS NP_697186.1 23501059 1165805 complement(166019..166864) 1 NC_004310.3 identified by similarity to GP:15073322; hypothetical protein 166864 1165805 BR0148 Brucella suis 1330 hypothetical protein NP_697186.1 166019 R 204722 CDS NP_697187.1 23501060 1165806 complement(167187..167669) 1 NC_004310.3 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 167669 lspA 1165806 lspA Brucella suis 1330 lipoprotein signal peptidase NP_697187.1 167187 R 204722 CDS NP_697188.1 23501061 1165807 complement(167671..168564) 1 NC_004310.3 identified by match to protein family HMM PF00588; RNA methyltransferase 168564 1165807 BR0150 Brucella suis 1330 RNA methyltransferase NP_697188.1 167671 R 204722 CDS NP_697189.1 23501062 1165808 complement(168561..169706) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2473; SAM dependent methyltransferase 169706 1165808 BR0151 Brucella suis 1330 SAM dependent methyltransferase NP_697189.1 168561 R 204722 CDS NP_697190.1 23501063 1165809 complement(169819..170142) 1 NC_004310.3 identified by similarity to GP:15073316; hypothetical protein 170142 1165809 BR0152 Brucella suis 1330 hypothetical protein NP_697190.1 169819 R 204722 CDS NP_697191.1 23501064 1165810 complement(170152..170436) 1 NC_004310.3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 170436 ihfB 1165810 ihfB Brucella suis 1330 integration host factor subunit beta NP_697191.1 170152 R 204722 CDS NP_697192.1 23501065 1165811 complement(170483..171478) 1 NC_004310.3 identified by match to protein family HMM PF01343; match to protein family HMM TIGR00706; signal peptide peptidase SppA 171478 sppA 1165811 sppA Brucella suis 1330 signal peptide peptidase SppA NP_697192.1 170483 R 204722 CDS NP_697193.1 23501066 1165812 171997..172650 1 NC_004310.3 identified by similarity to GP:15155241; hypothetical protein 172650 1165812 BR0155 Brucella suis 1330 hypothetical protein NP_697193.1 171997 D 204722 CDS NP_697194.1 23501067 1165813 172973..173587 1 NC_004310.3 identified by similarity to GP:15155240; match to protein family HMM PF03968; hypothetical protein 173587 1165813 BR0156 Brucella suis 1330 hypothetical protein NP_697194.1 172973 D 204722 CDS NP_697195.1 23501068 1165814 173599..174432 1 NC_004310.3 identified by similarity to GP:17983823; match to protein family HMM PF00005; ABC transporter ATP-binding protein 174432 1165814 BR0157 Brucella suis 1330 ABC transporter ATP-binding protein NP_697195.1 173599 D 204722 CDS NP_697196.1 23501069 1165815 174728..176230 1 NC_004310.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 176230 rpoN 1165815 rpoN Brucella suis 1330 RNA polymerase factor sigma-54 NP_697196.1 174728 D 204722 CDS NP_697197.1 23501070 1165816 complement(176379..176744) 1 NC_004310.3 hypothetical protein 176744 1165816 BR0159 Brucella suis 1330 hypothetical protein NP_697197.1 176379 R 204722 CDS NP_697198.1 23501071 1165817 176980..177573 1 NC_004310.3 identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 177573 yfiA 1165817 yfiA Brucella suis 1330 ribosomal subunit interface protein NP_697198.1 176980 D 204722 CDS NP_697199.1 23501072 1165818 177676..178140 1 NC_004310.3 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system, nitrogen regulatory IIA component 178140 ptsN 1165818 ptsN Brucella suis 1330 PTS system, nitrogen regulatory IIA component NP_697199.1 177676 D 204722 CDS NP_697200.1 23501073 1165819 complement(178221..178466) 1 NC_004310.3 identified by similarity to GP:15073342; hypothetical protein 178466 1165819 BR0162 Brucella suis 1330 hypothetical protein NP_697200.1 178221 R 204722 CDS NP_697201.1 23501074 1165820 complement(178572..179054) 1 NC_004310.3 identified by similarity to OMNI:CC3592; match to protein family HMM PF00011; heat shock protein 20 179054 1165820 BR0163 Brucella suis 1330 heat shock protein 20 NP_697201.1 178572 R 204722 CDS NP_697202.1 23501075 1165821 complement(179085..179297) 1 NC_004310.3 hypothetical protein 179297 1165821 BR0164 Brucella suis 1330 hypothetical protein NP_697202.1 179085 R 204722 CDS NP_697203.1 23501076 1165822 complement(179266..179763) 1 NC_004310.3 identified by similarity to GP:15158767; hypothetical protein 179763 1165822 BR0165 Brucella suis 1330 hypothetical protein NP_697203.1 179266 R 204722 CDS NP_697204.1 23501077 1165823 179868..180614 1 NC_004310.3 identified by similarity to EGAD:18451; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 180614 nth 1165823 nth Brucella suis 1330 endonuclease III NP_697204.1 179868 D 204722 CDS NP_697205.1 23501078 1165824 complement(180655..181368) 1 NC_004310.3 role in sulfur assimilation; CysZ-like protein 181368 1165824 BR0167 Brucella suis 1330 CysZ-like protein NP_697205.1 180655 R 204722 CDS NP_697206.1 23501079 1165825 complement(181365..181625) 1 NC_004310.3 hypothetical protein 181625 1165825 BR0168 Brucella suis 1330 hypothetical protein NP_697206.1 181365 R 204722 CDS NP_697207.1 23501080 1165826 181628..182620 1 NC_004310.3 identified by match to protein family HMM PF00294; carbohydrate kinase 182620 1165826 BR0169 Brucella suis 1330 carbohydrate kinase NP_697207.1 181628 D 204722 CDS NP_697208.1 23501081 1165827 complement(182639..183295) 1 NC_004310.3 identified by similarity to GP:15155036; match to protein family HMM PF03458; hypothetical protein 183295 1165827 BR0170 Brucella suis 1330 hypothetical protein NP_697208.1 182639 R 204722 CDS NP_697209.1 23501082 1165828 complement(183428..184120) 1 NC_004310.3 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 184120 grpE 1165828 grpE Brucella suis 1330 heat shock protein GrpE NP_697209.1 183428 R 204722 CDS NP_697210.1 23501083 1165829 complement(184226..185350) 1 NC_004310.3 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 185350 hrcA 1165829 hrcA Brucella suis 1330 heat-inducible transcription repressor NP_697210.1 184226 R 204722 CDS NP_697211.1 23501084 1165830 185518..186234 1 NC_004310.3 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 186234 rph 1165830 rph Brucella suis 1330 ribonuclease PH NP_697211.1 185518 D 204722 CDS NP_697212.1 23501085 1165831 186408..186812 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 186812 1165831 BR0174 Brucella suis 1330 glyoxalase NP_697212.1 186408 D 204722 CDS NP_697213.1 23501086 1165832 186815..187477 1 NC_004310.3 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 187477 1165832 BR0175 Brucella suis 1330 deoxyribonucleotide triphosphate pyrophosphatase NP_697213.1 186815 D 204722 CDS NP_697214.1 23501087 1165833 187531..188688 1 NC_004310.3 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 188688 1165833 BR0176 Brucella suis 1330 coproporphyrinogen III oxidase NP_697214.1 187531 D 204722 CDS NP_697215.1 23501088 1165834 188754..189611 1 NC_004310.3 identified by similarity to OMNI:CC0144; match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase 189611 1165834 BR0177 Brucella suis 1330 tetrapyrrole methylase NP_697215.1 188754 D 204722 CDS NP_697216.1 23501089 1165835 189608..189988 1 NC_004310.3 identified by similarity to GP:15073266; match to protein family HMM PF02021; hypothetical protein 189988 1165835 BR0178 Brucella suis 1330 hypothetical protein NP_697216.1 189608 D 204722 CDS NP_697217.1 23501090 1165836 190208..191641 1 NC_004310.3 identified by similarity to SP:P11098; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; siroheme synthase 191641 cysG 1165836 cysG Brucella suis 1330 siroheme synthase NP_697217.1 190208 D 204722 CDS NP_697218.1 23501091 1165837 191659..191961 1 NC_004310.3 identified by similarity to GP:15156533; hypothetical protein 191961 1165837 BR0180 Brucella suis 1330 hypothetical protein NP_697218.1 191659 D 204722 CDS NP_697219.1 23501092 1165838 191982..193652 1 NC_004310.3 identified by similarity to OMNI:CC1119; match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase (NADPH) hemoprotein subunit beta 193652 cysI 1165838 cysI Brucella suis 1330 sulfite reductase (NADPH) hemoprotein subunit beta NP_697219.1 191982 D 204722 CDS NP_697220.1 23501093 1165839 193642..194400 1 NC_004310.3 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 194400 cysH 1165839 cysH Brucella suis 1330 phosphoadenosine phosphosulfate reductase NP_697220.1 193642 D 204722 CDS NP_697221.1 23501094 1165840 194453..194977 1 NC_004310.3 identified by similarity to GP:15156535; hypothetical protein 194977 1165840 BR0183 Brucella suis 1330 hypothetical protein NP_697221.1 194453 D 204722 CDS NP_697222.1 23501095 1165841 195045..195338 1 NC_004310.3 identified by similarity to GP:14021352; hypothetical protein 195338 1165841 BR0184 Brucella suis 1330 hypothetical protein NP_697222.1 195045 D 204722 CDS NP_697223.1 23501096 1165842 complement(195339..195917) 1 NC_004310.3 identified by similarity to OMNI:CC0659; match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase 195917 ogt 1165842 ogt Brucella suis 1330 methylated-DNA--protein-cysteine methyltransferase NP_697223.1 195339 R 204722 CDS NP_697224.1 23501097 1165843 196175..196420 1 NC_004310.3 identified by similarity to GP:14025509; hypothetical protein 196420 1165843 BR0186 Brucella suis 1330 hypothetical protein NP_697224.1 196175 D 204722 CDS NP_697225.1 23501098 1165844 complement(196473..196862) 1 NC_004310.3 identified by similarity to GP:15073804; hypothetical protein 196862 1165844 BR0187 Brucella suis 1330 hypothetical protein NP_697225.1 196473 R 204722 CDS NP_697226.1 23501099 1165845 197176..200961 1 NC_004310.3 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 200961 metH 1165845 metH Brucella suis 1330 B12-dependent methionine synthase NP_697226.1 197176 D 204722 CDS NP_697227.1 23501100 1165846 complement(200925..201092) 1 NC_004310.3 hypothetical protein 201092 1165846 BR0189 Brucella suis 1330 hypothetical protein NP_697227.1 200925 R 204722 CDS NP_697228.1 23501101 1165847 201282..201989 1 NC_004310.3 identified by match to protein family HMM PF00196; match to protein family HMM PF03472; LuxR family transcriptional regulator 201989 1165847 BR0190 Brucella suis 1330 LuxR family transcriptional regulator NP_697228.1 201282 D 204722 CDS NP_697229.1 23501102 1165848 202104..203474 1 NC_004310.3 identified by match to protein family HMM PF00202; aminotransferase 203474 1165848 BR0191 Brucella suis 1330 aminotransferase NP_697229.1 202104 D 204722 CDS NP_697230.1 23501103 1165849 complement(203514..203699) 1 NC_004310.3 hypothetical protein 203699 1165849 BR0192 Brucella suis 1330 hypothetical protein NP_697230.1 203514 R 204722 CDS NP_697231.1 23501104 1165850 203878..204780 1 NC_004310.3 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 204780 cysD 1165850 cysD Brucella suis 1330 sulfate adenylyltransferase subunit 2 NP_697231.1 203878 D 204722 CDS NP_697232.1 23501105 1165851 204780..206714 1 NC_004310.3 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 206714 cysNC 1165851 cysNC Brucella suis 1330 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase NP_697232.1 204780 D 204722 CDS NP_697233.1 23501106 1165852 206762..207562 1 NC_004310.3 identified by similarity to SP:P22255; match to protein family HMM PF00459; match to protein family HMM TIGR01331; 3'(2'),5'-bisphosphate nucleotidase 207562 cysQ 1165852 cysQ Brucella suis 1330 3'(2'),5'-bisphosphate nucleotidase NP_697233.1 206762 D 204722 CDS NP_697234.1 23501107 1165854 complement(207824..208585) 1 NC_004310.3 identified by match to protein family HMM PF00027; Crp/Fnr family transcriptional regulator 208585 1165854 BR0196 Brucella suis 1330 Crp/Fnr family transcriptional regulator NP_697234.1 207824 R 204722 CDS NP_697235.1 23501108 1165856 209538..209669 1 NC_004310.3 hypothetical protein 209669 1165856 BR0198 Brucella suis 1330 hypothetical protein NP_697235.1 209538 D 204722 CDS NP_697236.1 23501109 1165857 209891..210682 1 NC_004310.3 identified by similarity to SP:P09392; match to protein family HMM PF00455; glycerol-3-phosphate transcriptional regulator 210682 glpR 1165857 glpR Brucella suis 1330 glycerol-3-phosphate transcriptional regulator NP_697236.1 209891 D 204722 CDS NP_697237.1 23501110 1165858 210764..212275 1 NC_004310.3 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 212275 glpD 1165858 glpD Brucella suis 1330 glycerol-3-phosphate dehydrogenase NP_697237.1 210764 D 204722 CDS NP_697238.1 23501111 1165860 213612..215129 1 NC_004310.3 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 215129 1165860 BR0202 Brucella suis 1330 aldehyde dehydrogenase NP_697238.1 213612 D 204722 CDS NP_697239.1 23501112 1165861 215610..216644 1 NC_004310.3 identified by similarity to SP:P42327; match to protein family HMM PF00107; alcohol dehydrogenase 216644 1165861 BR0203 Brucella suis 1330 alcohol dehydrogenase NP_697239.1 215610 D 204722 CDS NP_697240.1 23501113 1165862 216735..217067 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5214; match to protein family HMM PF05610; hypothetical protein 217067 1165862 BR0204 Brucella suis 1330 hypothetical protein NP_697240.1 216735 D 204722 CDS NP_697241.1 23501114 1165865 219596..220165 1 NC_004310.3 hypothetical protein 220165 1165865 BR0207 Brucella suis 1330 hypothetical protein NP_697241.1 219596 D 204722 CDS NP_697242.1 23501115 1165866 complement(220207..220305) 1 NC_004310.3 hypothetical protein 220305 1165866 BR0208 Brucella suis 1330 hypothetical protein NP_697242.1 220207 R 204722 CDS NP_697243.1 23501116 1165867 220300..220455 1 NC_004310.3 hypothetical protein 220455 1165867 BR0209 Brucella suis 1330 hypothetical protein NP_697243.1 220300 D 204722 CDS NP_697244.1 23501117 1165868 220468..221901 1 NC_004310.3 identified by similarity to EGAD:17385; match to protein family HMM PF00171; aldehyde dehydrogenase 221901 1165868 BR0210 Brucella suis 1330 aldehyde dehydrogenase NP_697244.1 220468 D 204722 CDS NP_697245.1 23501118 1165869 complement(221946..222722) 1 NC_004310.3 identified by match to protein family HMM PF00528; ABC transporter permease 222722 1165869 BR0211 Brucella suis 1330 ABC transporter permease NP_697245.1 221946 R 204722 CDS NP_697246.1 23501119 1165870 complement(222719..223417) 1 NC_004310.3 identified by similarity to EGAD:24145; match to protein family HMM PF03070; transcriptional regulator TenA 223417 1165870 BR0212 Brucella suis 1330 transcriptional regulator TenA NP_697246.1 222719 R 204722 CDS NP_697247.1 23501120 1165871 complement(223414..224382) 1 NC_004310.3 ABC transporter periplasmic substrate-binding protein 224382 1165871 BR0213 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_697247.1 223414 R 204722 CDS NP_697248.1 23501121 1165872 complement(224406..225017) 1 NC_004310.3 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 225017 thiE 1165872 thiE Brucella suis 1330 thiamine-phosphate pyrophosphorylase NP_697248.1 224406 R 204722 CDS NP_697249.1 23501122 1165873 complement(225014..225784) 1 NC_004310.3 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 225784 thiG 1165873 thiG Brucella suis 1330 thiazole synthase NP_697249.1 225014 R 204722 CDS NP_697250.1 23501123 1165874 complement(225786..225983) 1 NC_004310.3 identified by similarity to SP:O32583; match to protein family HMM PF02597; match to protein family HMM TIGR01683; thiamine biosynthesis protein ThiS 225983 1165874 BR0216 Brucella suis 1330 thiamine biosynthesis protein ThiS NP_697250.1 225786 R 204722 CDS NP_697251.1 23501124 1165875 complement(225980..226984) 1 NC_004310.3 identified by match to protein family HMM PF01266; D-amino acid oxidase 226984 1165875 BR0217 Brucella suis 1330 D-amino acid oxidase NP_697251.1 225980 R 204722 CDS NP_697252.1 23501125 1165876 complement(226984..227859) 1 NC_004310.3 identified by match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase 227859 thiD 1165876 thiD Brucella suis 1330 phosphomethylpyrimidine kinase NP_697252.1 226984 R 204722 CDS NP_697253.1 23501126 1165877 228288..230399 1 NC_004310.3 identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein 230399 1165877 BR0219 Brucella suis 1330 sensory box protein NP_697253.1 228288 D 204722 CDS NP_697254.1 23501127 1165878 230498..232978 1 NC_004310.3 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 232978 1165878 BR0220 Brucella suis 1330 copper-translocating P-type ATPase NP_697254.1 230498 D 204722 CDS NP_697255.1 23501128 1165879 complement(232958..233407) 1 NC_004310.3 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 233407 1165879 BR0221 Brucella suis 1330 MerR family transcriptional regulator NP_697255.1 232958 R 204722 CDS NP_697256.1 23501129 1165880 complement(233513..234259) 1 NC_004310.3 identified by match to protein family HMM PF00528; ABC transporter permease 234259 1165880 BR0222 Brucella suis 1330 ABC transporter permease NP_697256.1 233513 R 204722 CDS NP_697257.1 23501130 1165881 complement(234256..235194) 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 235194 1165881 BR0223 Brucella suis 1330 ABC transporter ATP-binding protein NP_697257.1 234256 R 204722 CDS NP_697258.1 23501131 1165882 complement(235191..236351) 1 NC_004310.3 identified by similarity to SP:P33361; match to protein family HMM PF00528; ABC transporter permease 236351 1165882 BR0224 Brucella suis 1330 ABC transporter permease NP_697258.1 235191 R 204722 CDS NP_697259.1 23501132 1165883 complement(236424..237338) 1 NC_004310.3 identified by similarity to GP:17983752; match to protein family HMM PF04069; ABC transporter periplasmic substrate-binding protein 237338 1165883 BR0225 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_697259.1 236424 R 204722 CDS NP_697260.1 23501133 1165884 complement(237524..238189) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0782; hypothetical protein 238189 1165884 BR0226 Brucella suis 1330 hypothetical protein NP_697260.1 237524 R 204722 CDS NP_697261.1 23501134 1165885 complement(238479..239744) 1 NC_004310.3 identified by similarity to EGAD:22862; match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase 239744 1165885 BR0227 Brucella suis 1330 glutamate dehydrogenase NP_697261.1 238479 R 204722 CDS NP_697262.1 23501135 1165886 239935..240102 1 NC_004310.3 hypothetical protein 240102 1165886 BR0228 Brucella suis 1330 hypothetical protein NP_697262.1 239935 D 204722 CDS NP_697263.1 23501136 1165887 240071..241324 1 NC_004310.3 identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373; sarcosine oxidase subunit beta 241324 soxB 1165887 soxB Brucella suis 1330 sarcosine oxidase subunit beta NP_697263.1 240071 D 204722 CDS NP_697264.1 23501137 1165888 241343..241648 1 NC_004310.3 identified by similarity to EGAD:43131; match to protein family HMM PF04267; match to protein family HMM TIGR01374; sarcosine oxidase subunit delta 241648 soxD 1165888 soxD Brucella suis 1330 sarcosine oxidase subunit delta NP_697264.1 241343 D 204722 CDS NP_697265.1 23501138 1165889 241648..244647 1 NC_004310.3 identified by similarity to EGAD:43132; match to protein family HMM PF01571; match to protein family HMM TIGR01372; sarcosine oxidase subunit alpha 244647 soxA 1165889 soxA Brucella suis 1330 sarcosine oxidase subunit alpha NP_697265.1 241648 D 204722 CDS NP_697266.1 23501139 1165890 244658..245212 1 NC_004310.3 identified by similarity to EGAD:43133; match to protein family HMM PF04268; sarcosine oxidase subunit gamma 245212 soxG 1165890 soxG Brucella suis 1330 sarcosine oxidase subunit gamma NP_697266.1 244658 D 204722 CDS NP_697267.1 23501140 1165891 complement(245265..246113) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5639; hypothetical protein 246113 1165891 BR0233 Brucella suis 1330 hypothetical protein NP_697267.1 245265 R 204722 CDS NP_697268.1 23501141 1165892 complement(246171..246965) 1 NC_004310.3 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 246965 1165892 BR0234 Brucella suis 1330 IclR family transcriptional regulator NP_697268.1 246171 R 204722 CDS NP_697269.1 23501142 1165893 247123..248442 1 NC_004310.3 identified by match to protein family HMM PF01547; sugar ABC transporter periplasmic sugar-binding protein 248442 1165893 BR0235 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_697269.1 247123 D 204722 CDS NP_697270.1 23501143 1165894 248503..249426 1 NC_004310.3 identified by match to protein family HMM PF00528; sugar ABC transporter permease 249426 1165894 BR0236 Brucella suis 1330 sugar ABC transporter permease NP_697270.1 248503 D 204722 CDS NP_697271.1 23501144 1165895 249429..250304 1 NC_004310.3 identified by match to protein family HMM PF00528; sugar ABC transporter permease 250304 1165895 BR0237 Brucella suis 1330 sugar ABC transporter permease NP_697271.1 249429 D 204722 CDS NP_697272.1 23501145 1165896 250312..251403 1 NC_004310.3 identified by similarity to SP:Q00752; match to protein family HMM PF00005; match to protein family HMM PF03459; sugar ABC transporter ATP-binding protein 251403 1165896 BR0238 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_697272.1 250312 D 204722 CDS NP_697273.1 23501146 1165897 251406..252524 1 NC_004310.3 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase 252524 1165897 BR0239 Brucella suis 1330 mandelate racemase NP_697273.1 251406 D 204722 CDS NP_697274.1 23501147 1165898 252521..252865 1 NC_004310.3 identified by similarity to GP:15140572; match to protein family HMM PF05336; hypothetical protein 252865 1165898 BR0240 Brucella suis 1330 hypothetical protein NP_697274.1 252521 D 204722 CDS NP_697275.1 23501148 1165899 252858..253937 1 NC_004310.3 identified by match to protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 253937 1165899 BR0241 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_697275.1 252858 D 204722 CDS NP_697276.1 23501149 1165900 253940..254038 1 NC_004310.3 hypothetical protein 254038 1165900 BR0242 Brucella suis 1330 hypothetical protein NP_697276.1 253940 D 204722 CDS NP_697277.1 23501150 1165901 254042..254776 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 254776 1165901 BR0243 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_697277.1 254042 D 204722 CDS NP_697278.1 23501151 1165902 254817..255662 1 NC_004310.3 identified by similarity to GP:15140576; match to protein family HMM PF01557; fumarylacetoacetate hydrolase 255662 1165902 BR0244 Brucella suis 1330 fumarylacetoacetate hydrolase NP_697278.1 254817 D 204722 CDS NP_697279.1 23501152 1165903 255676..256953 1 NC_004310.3 identified by match to protein family HMM PF01188; mandelate racemase 256953 1165903 BR0245 Brucella suis 1330 mandelate racemase NP_697279.1 255676 D 204722 CDS NP_697280.1 23501153 1165904 complement(257352..257903) 1 NC_004310.3 hypothetical protein 257903 1165904 BR0246 Brucella suis 1330 hypothetical protein NP_697280.1 257352 R 204722 CDS NP_697281.1 23501154 1165906 complement(259175..259348) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5069; match to protein family HMM PF03884; zinc-binding protein 259348 1165906 BR0247 Brucella suis 1330 zinc-binding protein NP_697281.1 259175 R 204722 CDS NP_697282.1 23501155 1165907 complement(259400..260026) 1 NC_004310.3 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 260026 maf 1165907 maf Brucella suis 1330 Maf-like protein NP_697282.1 259400 R 204722 CDS NP_697283.1 23501156 1165908 complement(260060..260278) 1 NC_004310.3 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 260278 infA 1165908 infA Brucella suis 1330 translation initiation factor IF-1 NP_697283.1 260060 R 204722 CDS NP_697284.1 23501157 1165909 complement(260390..260863) 1 NC_004310.3 identified by match to protein family HMM PF01451; protein phosphatase 260863 1165909 BR0250 Brucella suis 1330 protein phosphatase NP_697284.1 260390 R 204722 CDS NP_697285.1 23501158 1165910 complement(260870..261352) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5073; hypothetical protein 261352 1165910 BR0251 Brucella suis 1330 hypothetical protein NP_697285.1 260870 R 204722 CDS NP_697286.1 23501159 1165911 complement(261359..262651) 1 NC_004310.3 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 262651 hisD 1165911 hisD Brucella suis 1330 histidinol dehydrogenase NP_697286.1 261359 R 204722 CDS NP_697287.1 23501160 1165912 complement(262726..263166) 1 NC_004310.3 identified by similarity to GP:15073540; hypothetical protein 263166 1165912 BR0253 Brucella suis 1330 hypothetical protein NP_697287.1 262726 R 204722 CDS NP_697288.1 23501161 1165913 complement(263437..264726) 1 NC_004310.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 264726 murA 1165913 murA Brucella suis 1330 UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_697288.1 263437 R 204722 CDS NP_697289.1 23501162 1165914 complement(264949..265128) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5077; hypothetical protein 265128 1165914 BR0255 Brucella suis 1330 hypothetical protein NP_697289.1 264949 R 204722 CDS NP_697290.1 23501163 1165916 265442..267196 1 NC_004310.3 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase site specific recombinase 267196 1165916 BR0256 Brucella suis 1330 phage integrase site specific recombinase NP_697290.1 265442 D 204722 CDS NP_697291.1 23501164 1165917 complement(267186..267299) 1 NC_004310.3 hypothetical protein 267299 1165917 BR0257 Brucella suis 1330 hypothetical protein NP_697291.1 267186 R 204722 CDS NP_697292.1 23501165 1165918 267291..267713 1 NC_004310.3 identified by match to protein family HMM PF02498; BRO family protein 267713 1165918 BR0258 Brucella suis 1330 BRO family protein NP_697292.1 267291 D 204722 CDS NP_697293.1 23501166 1165919 267726..267920 1 NC_004310.3 hypothetical protein 267920 1165919 BR0259 Brucella suis 1330 hypothetical protein NP_697293.1 267726 D 204722 CDS NP_697294.1 23501167 1165920 268512..269129 1 NC_004310.3 identified by match to protein family HMM PF00239; resolvase site-specific recombinase 269129 1165920 BR0260 Brucella suis 1330 resolvase site-specific recombinase NP_697294.1 268512 D 204722 CDS NP_697295.1 23501168 1165921 269687..271051 1 NC_004310.3 hypothetical protein 271051 1165921 BR0261 Brucella suis 1330 hypothetical protein NP_697295.1 269687 D 204722 CDS NP_697296.1 23501169 1165922 271639..271818 1 NC_004310.3 hypothetical protein 271818 1165922 BR0262 Brucella suis 1330 hypothetical protein NP_697296.1 271639 D 204722 CDS NP_697297.1 23501170 1165923 complement(272292..272576) 1 NC_004310.3 hypothetical protein 272576 1165923 BR0263 Brucella suis 1330 hypothetical protein NP_697297.1 272292 R 204722 CDS NP_697298.1 23501171 1165924 complement(272690..272950) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3521; hypothetical protein 272950 1165924 BR0264 Brucella suis 1330 hypothetical protein NP_697298.1 272690 R 204722 CDS NP_697299.1 23501172 1165925 273034..273423 1 NC_004310.3 hypothetical protein 273423 1165925 BR0265 Brucella suis 1330 hypothetical protein NP_697299.1 273034 D 204722 CDS NP_697300.1 23501173 1165926 complement(273876..273980) 1 NC_004310.3 hypothetical protein 273980 1165926 BR0266 Brucella suis 1330 hypothetical protein NP_697300.1 273876 R 204722 CDS NP_697301.1 23501174 1165927 274015..274857 1 NC_004310.3 identified by similarity to SP:P42888; match to protein family HMM PF01774; urease accessory protein UreD 274857 ureD-1 1165927 ureD-1 Brucella suis 1330 urease accessory protein UreD NP_697301.1 274015 D 204722 CDS NP_697302.1 23501175 1165928 275010..275312 1 NC_004310.3 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 275312 ureA 1165928 ureA Brucella suis 1330 urease subunit gamma NP_697302.1 275010 D 204722 CDS NP_697303.1 23501176 1165929 275479..275784 1 NC_004310.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 275784 ureB 1165929 ureB Brucella suis 1330 urease subunit beta NP_697303.1 275479 D 204722 CDS NP_697304.1 23501177 1165930 275803..277515 1 NC_004310.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 277515 ureC 1165930 ureC Brucella suis 1330 urease subunit alpha NP_697304.1 275803 D 204722 CDS NP_697305.1 23501178 1165931 277531..278019 1 NC_004310.3 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 278019 ureE 1165931 ureE Brucella suis 1330 urease accessory protein UreE NP_697305.1 277531 D 204722 CDS NP_697306.1 23501179 1165932 277991..278677 1 NC_004310.3 identified by similarity to SP:Q07402; match to protein family HMM PF01730; urease accessory protein UreF 278677 1165932 BR0272 Brucella suis 1330 urease accessory protein UreF NP_697306.1 277991 D 204722 CDS NP_697307.1 23501180 1165933 278674..279300 1 NC_004310.3 identified by similarity to EGAD:19477; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 279300 ureG-1 1165933 ureG-1 Brucella suis 1330 urease accessory protein UreG NP_697307.1 278674 D 204722 CDS NP_697308.1 23501181 1165935 complement(279657..281282) 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 281282 1165935 BR0274 Brucella suis 1330 sensor histidine kinase NP_697308.1 279657 R 204722 CDS NP_697309.1 23501182 1165936 complement(281299..281604) 1 NC_004310.3 hypothetical protein 281604 1165936 BR0275 Brucella suis 1330 hypothetical protein NP_697309.1 281299 R 204722 CDS NP_697310.1 23501183 1165937 281567..282718 1 NC_004310.3 identified by similarity to GP:15075163; match to protein family HMM TIGR01730; transporter 282718 1165937 BR0276 Brucella suis 1330 transporter NP_697310.1 281567 D 204722 CDS NP_697311.1 23501184 1165938 282733..285864 1 NC_004310.3 identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein 285864 1165938 BR0277 Brucella suis 1330 AcrB/AcrD/AcrF multidrug efflux protein NP_697311.1 282733 D 204722 CDS NP_697312.1 23501185 1165939 complement(285987..287456) 1 NC_004310.3 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase 287456 dhT 1165939 dhT Brucella suis 1330 phenylhydantoinase NP_697312.1 285987 R 204722 CDS NP_697313.1 23501186 1165940 complement(287508..288755) 1 NC_004310.3 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 288755 1165940 BR0279 Brucella suis 1330 allantoate amidohydrolase NP_697313.1 287508 R 204722 CDS NP_697314.1 23501187 1165941 288974..289657 1 NC_004310.3 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 289657 1165941 BR0280 Brucella suis 1330 TetR family transcriptional regulator NP_697314.1 288974 D 204722 CDS NP_697315.1 23501188 1165942 289654..290043 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 290043 1165942 BR0281 Brucella suis 1330 MutT/nudix family protein NP_697315.1 289654 D 204722 CDS NP_697316.1 23501189 1165943 complement(290088..291398) 1 NC_004310.3 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase 291398 1165943 BR0282 Brucella suis 1330 dihydropyrimidine dehydrogenase NP_697316.1 290088 R 204722 CDS NP_697317.1 23501190 1165944 complement(291402..292907) 1 NC_004310.3 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase 292907 1165944 BR0283 Brucella suis 1330 oxidoreductase NP_697317.1 291402 R 204722 CDS NP_697318.1 23501191 1165945 complement(293086..293538) 1 NC_004310.3 identified by similarity to GP:15073317; hypothetical protein 293538 1165945 BR0284 Brucella suis 1330 hypothetical protein NP_697318.1 293086 R 204722 CDS NP_697319.1 23501192 1165946 293689..295338 1 NC_004310.3 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 295338 pgi 1165946 pgi Brucella suis 1330 glucose-6-phosphate isomerase NP_697319.1 293689 D 204722 CDS NP_697320.1 23501193 1165947 295574..296635 1 NC_004310.3 identified by similarity to GP:15073237; hypothetical protein 296635 1165947 BR0286 Brucella suis 1330 hypothetical protein NP_697320.1 295574 D 204722 CDS NP_697321.1 23501194 1165948 296632..297381 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 297381 1165948 BR0287 Brucella suis 1330 HAD superfamily hydrolase NP_697321.1 296632 D 204722 CDS NP_697322.1 23501195 1165949 complement(297354..298226) 1 NC_004310.3 identified by similarity to OMNI:NTL03PA01240; hypothetical protein 298226 1165949 BR0288 Brucella suis 1330 hypothetical protein NP_697322.1 297354 R 204722 CDS NP_697323.1 23501196 1165950 complement(298252..299916) 1 NC_004310.3 activates fatty acids by binding to coenzyme A; Long-chain-fatty-acid--CoA ligase 299916 fadD 1165950 fadD Brucella suis 1330 Long-chain-fatty-acid--CoA ligase NP_697323.1 298252 R 204722 CDS NP_697324.1 23501197 1165951 complement(300348..300977) 1 NC_004310.3 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 300977 1165951 BR0290 Brucella suis 1330 TetR family transcriptional regulator NP_697324.1 300348 R 204722 CDS NP_697325.1 23501198 1165952 301150..302343 1 NC_004310.3 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein 302343 1165952 BR0291 Brucella suis 1330 HlyD family secretion protein NP_697325.1 301150 D 204722 CDS NP_697326.1 23501199 1165953 302340..305495 1 NC_004310.3 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; hydrophobe/amphiphile efflux-1 family protein 305495 1165953 BR0292 Brucella suis 1330 hydrophobe/amphiphile efflux-1 family protein NP_697326.1 302340 D 204722 CDS NP_697327.1 23501200 1165954 complement(305606..305773) 1 NC_004310.3 hypothetical protein 305773 1165954 BR0293 Brucella suis 1330 hypothetical protein NP_697327.1 305606 R 204722 CDS NP_697328.1 23501201 1165955 complement(305994..306134) 1 NC_004310.3 hypothetical protein 306134 1165955 BR0294 Brucella suis 1330 hypothetical protein NP_697328.1 305994 R 204722 CDS NP_697329.1 23501202 1165956 complement(306203..307045) 1 NC_004310.3 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 307045 1165956 BR0295 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_697329.1 306203 R 204722 CDS NP_697330.1 23501203 1165957 307311..309203 1 NC_004310.3 identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein 309203 1165957 BR0296 Brucella suis 1330 glycosyl transferase group 2 family protein NP_697330.1 307311 D 204722 CDS NP_697331.1 23501204 1165958 complement(309131..310090) 1 NC_004310.3 identified by similarity to GP:15155336; match to protein family HMM PF03976; hypothetical protein 310090 1165958 BR0297 Brucella suis 1330 hypothetical protein NP_697331.1 309131 R 204722 CDS NP_697332.1 23501205 1165959 310223..311539 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 311539 1165959 BR0298 Brucella suis 1330 sensor histidine kinase NP_697332.1 310223 D 204722 CDS NP_697333.1 23501206 1165960 complement(311669..312211) 1 NC_004310.3 identified by similarity to GP:15073446; hypothetical protein 312211 1165960 BR0299 Brucella suis 1330 hypothetical protein NP_697333.1 311669 R 204722 CDS NP_697334.1 23501207 1165961 complement(312383..312724) 1 NC_004310.3 hypothetical protein 312724 1165961 BR0300 Brucella suis 1330 hypothetical protein NP_697334.1 312383 R 204722 CDS NP_697335.1 23501208 1165962 312814..314025 1 NC_004310.3 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase 314025 argD 1165962 argD Brucella suis 1330 acetylornithine transaminase NP_697335.1 312814 D 204722 CDS NP_697336.1 23501209 1165963 314030..314968 1 NC_004310.3 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 314968 argF 1165963 argF Brucella suis 1330 ornithine carbamoyltransferase NP_697336.1 314030 D 204722 CDS NP_697337.1 23501210 1165964 314970..315992 1 NC_004310.3 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 315992 hslO 1165964 hslO Brucella suis 1330 heat shock protein 33 NP_697337.1 314970 D 204722 CDS NP_697338.1 23501211 1165965 complement(316033..316425) 1 NC_004310.3 protein associated with Co2+ and Mg2+ efflux; ApaG protein 316425 apaG 1165965 apaG Brucella suis 1330 ApaG protein NP_697338.1 316033 R 204722 CDS NP_697339.1 23501212 1165966 complement(316794..317990) 1 NC_004310.3 catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; O-succinylhomoserine sulfhydrylase 317990 metZ 1165966 metZ Brucella suis 1330 O-succinylhomoserine sulfhydrylase NP_697339.1 316794 R 204722 CDS NP_697340.1 23501213 1165967 318417..319508 1 NC_004310.3 Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 319508 1165967 BR0306 Brucella suis 1330 2'-deoxycytidine 5'-triphosphate deaminase NP_697340.1 318417 D 204722 CDS NP_697341.1 23501214 1165968 319599..320615 1 NC_004310.3 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 320615 1165968 BR0307 Brucella suis 1330 AraC family transcriptional regulator NP_697341.1 319599 D 204722 CDS NP_697342.1 23501215 1165969 320702..320968 1 NC_004310.3 identified by similarity to GP:15155415; hypothetical protein 320968 1165969 BR0308 Brucella suis 1330 hypothetical protein NP_697342.1 320702 D 204722 CDS NP_697343.1 23501216 1165970 321068..321487 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6482; match to protein family HMM PF00188; hypothetical protein 321487 1165970 BR0309 Brucella suis 1330 hypothetical protein NP_697343.1 321068 D 204722 CDS NP_697344.1 23501217 1165971 321662..323029 1 NC_004310.3 identified by similarity to EGAD:8949; match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein F 323029 1165971 BR0310 Brucella suis 1330 DNA-damage-inducible protein F NP_697344.1 321662 D 204722 CDS NP_697345.1 23501218 1165972 complement(323031..324125) 1 NC_004310.3 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 324125 pyrD 1165972 pyrD Brucella suis 1330 dihydroorotate dehydrogenase 2 NP_697345.1 323031 R 204722 CDS NP_697346.1 23501219 1165973 complement(324122..324475) 1 NC_004310.3 identified by similarity to GP:15073480; hypothetical protein 324475 1165973 BR0312 Brucella suis 1330 hypothetical protein NP_697346.1 324122 R 204722 CDS NP_697347.1 23501220 1165974 324729..325184 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4408; hypothetical protein 325184 1165974 BR0313 Brucella suis 1330 hypothetical protein NP_697347.1 324729 D 204722 CDS NP_697348.1 23501221 1165975 complement(325275..326225) 1 NC_004310.3 identified by similarity to EGAD:139406; match to protein family HMM PF00561; match to protein family HMM TIGR01249; proline iminopeptidase 326225 pip 1165975 pip Brucella suis 1330 proline iminopeptidase NP_697348.1 325275 R 204722 CDS NP_697349.1 23501222 1165976 326455..327096 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 327096 1165976 BR0315 Brucella suis 1330 LuxR family transcriptional regulator NP_697349.1 326455 D 204722 CDS NP_697350.1 23501223 1165977 complement(327133..330657) 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase/response regulator 330657 1165977 BR0316 Brucella suis 1330 sensor histidine kinase/response regulator NP_697350.1 327133 R 204722 CDS NP_697351.1 23501224 1165978 complement(330942..331088) 1 NC_004310.3 hypothetical protein 331088 1165978 BR0317 Brucella suis 1330 hypothetical protein NP_697351.1 330942 R 204722 CDS NP_697352.1 23501225 1165979 331170..331586 1 NC_004310.3 homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 331586 mscL 1165979 mscL Brucella suis 1330 large-conductance mechanosensitive channel NP_697352.1 331170 D 204722 CDS NP_697353.1 23501226 1165980 complement(331662..332939) 1 NC_004310.3 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 332939 hemA 1165980 hemA Brucella suis 1330 5-aminolevulinate synthase NP_697353.1 331662 R 204722 CDS NP_697354.1 23501227 1165981 complement(333085..333786) 1 NC_004310.3 identified by match to protein family HMM PF01522; polysaccharide deacetylase 333786 1165981 BR0320 Brucella suis 1330 polysaccharide deacetylase NP_697354.1 333085 R 204722 CDS NP_697355.1 23501228 1165982 complement(333795..334514) 1 NC_004310.3 identified by similarity to GP:12837556; match to protein family HMM PF01755; glycosyl transferase 334514 1165982 BR0321 Brucella suis 1330 glycosyl transferase NP_697355.1 333795 R 204722 CDS NP_697356.1 23501229 1165983 complement(334644..335318) 1 NC_004310.3 identified by similarity to GP:15157577; hypothetical protein 335318 1165983 BR0322 Brucella suis 1330 hypothetical protein NP_697356.1 334644 R 204722 CDS NP_697357.1 23501230 1165984 complement(335410..335643) 1 NC_004310.3 hypothetical protein 335643 1165984 BR0323 Brucella suis 1330 hypothetical protein NP_697357.1 335410 R 204722 CDS NP_697358.1 23501231 1165985 complement(335686..336576) 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 336576 1165985 BR0324 Brucella suis 1330 LysR family transcriptional regulator NP_697358.1 335686 R 204722 CDS NP_697359.1 23501232 1165986 336698..337117 1 NC_004310.3 identified by similarity to OMNI:NTL03PA03432; match to protein family HMM PF03788; hypothetical protein 337117 1165986 BR0325 Brucella suis 1330 hypothetical protein NP_697359.1 336698 D 204722 CDS NP_697360.1 23501233 1165987 337104..337811 1 NC_004310.3 identified by similarity to OMNI:NTL03PA03431; match to protein family HMM PF04172; hypothetical protein 337811 1165987 BR0326 Brucella suis 1330 hypothetical protein NP_697360.1 337104 D 204722 CDS NP_697361.1 23501234 1165988 337934..338320 1 NC_004310.3 hypothetical protein 338320 1165988 BR0327 Brucella suis 1330 hypothetical protein NP_697361.1 337934 D 204722 CDS NP_697362.1 23501235 1165989 338358..339599 1 NC_004310.3 identified by similarity to GP:15155313; lipoprotein 339599 1165989 BR0328 Brucella suis 1330 lipoprotein NP_697362.1 338358 D 204722 CDS NP_697363.1 23501236 1165990 339686..340567 1 NC_004310.3 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 340567 panC 1165990 panC Brucella suis 1330 pantoate--beta-alanine ligase NP_697363.1 339686 D 204722 CDS NP_697364.1 23501237 1165991 340569..341396 1 NC_004310.3 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 341396 panB 1165991 panB Brucella suis 1330 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_697364.1 340569 D 204722 CDS NP_697365.1 23501238 1165992 complement(341593..342369) 1 NC_004310.3 identified by similarity to SP:Q44532; match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase 342369 fpr 1165992 fpr Brucella suis 1330 ferredoxin-NADP reductase NP_697365.1 341593 R 204722 CDS NP_697366.1 23501239 1165993 342491..342583 1 NC_004310.3 hypothetical protein 342583 1165993 BR0332 Brucella suis 1330 hypothetical protein NP_697366.1 342491 D 204722 CDS NP_697367.1 23501240 1165994 342772..343122 1 NC_004310.3 hypothetical protein 343122 1165994 BR0333 Brucella suis 1330 hypothetical protein NP_697367.1 342772 D 204722 CDS NP_697368.1 23501241 1165995 343161..344258 1 NC_004310.3 identified by similarity to EGAD:19651; match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 344258 nspC 1165995 nspC Brucella suis 1330 carboxynorspermidine decarboxylase NP_697368.1 343161 D 204722 CDS NP_697369.1 23501242 1165996 344439..345680 1 NC_004310.3 identified by similarity to GP:15141437; match to protein family HMM PF03435; hypothetical protein 345680 1165996 BR0335 Brucella suis 1330 hypothetical protein NP_697369.1 344439 D 204722 CDS NP_697370.1 23501243 1165997 complement(345696..345911) 1 NC_004310.3 hypothetical protein 345911 1165997 BR0336 Brucella suis 1330 hypothetical protein NP_697370.1 345696 R 204722 CDS NP_697371.1 23501244 1165998 complement(345936..346964) 1 NC_004310.3 identified by similarity to GP:9695312; match to protein family HMM PF05544; proline racemase 346964 1165998 BR0337 Brucella suis 1330 proline racemase NP_697371.1 345936 R 204722 CDS NP_697372.1 23501245 1165999 complement(347019..347126) 1 NC_004310.3 hypothetical protein 347126 1165999 BR0338 Brucella suis 1330 hypothetical protein NP_697372.1 347019 R 204722 CDS NP_697373.1 23501246 1166000 347417..348832 1 NC_004310.3 identified by similarity to SP:O82855; match to protein family HMM PF01554; match to protein family HMM TIGR00797; multidrug resistance protein NorM 348832 1166000 BR0339 Brucella suis 1330 multidrug resistance protein NorM NP_697373.1 347417 D 204722 CDS NP_697374.1 23501247 1166003 351026..351667 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 351667 1166003 BR0342 Brucella suis 1330 LuxR family transcriptional regulator NP_697374.1 351026 D 204722 CDS NP_697375.1 23501248 1166004 351955..352503 1 NC_004310.3 identified by similarity to GP:15162042; match to protein family HMM PF04290; hypothetical protein 352503 1166004 BR0343 Brucella suis 1330 hypothetical protein NP_697375.1 351955 D 204722 CDS NP_697376.1 23501249 1166005 352515..354083 1 NC_004310.3 identified by match to protein family HMM TIGR00786; TRAP dicarboxylate transporter subunit DctM 354083 1166005 BR0344 Brucella suis 1330 TRAP dicarboxylate transporter subunit DctM NP_697376.1 352515 D 204722 CDS NP_697377.1 23501250 1166006 354145..355263 1 NC_004310.3 identified by match to protein family HMM PF03480; match to protein family HMM TIGR01409; ABC transporter substrate-binding protein 355263 1166006 BR0345 Brucella suis 1330 ABC transporter substrate-binding protein NP_697377.1 354145 D 204722 CDS NP_697378.1 23501251 1166007 complement(355346..356164) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3955; hypothetical protein 356164 1166007 BR0346 Brucella suis 1330 hypothetical protein NP_697378.1 355346 R 204722 CDS NP_697379.1 23501252 1166008 complement(356177..357604) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3956; match to protein family HMM PF01522; hypothetical protein 357604 1166008 BR0347 Brucella suis 1330 hypothetical protein NP_697379.1 356177 R 204722 CDS NP_697380.1 23501253 1166009 357872..358147 1 NC_004310.3 identified by similarity to GP:15140674; hypothetical protein 358147 1166009 BR0348 Brucella suis 1330 hypothetical protein NP_697380.1 357872 D 204722 CDS NP_697381.1 23501254 1166010 358153..359631 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3958; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450; xanthine dehydrogenase 359631 1166010 BR0349 Brucella suis 1330 xanthine dehydrogenase NP_697381.1 358153 D 204722 CDS NP_697382.1 23501255 1166011 359644..361986 1 NC_004310.3 identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase 361986 1166011 BR0350 Brucella suis 1330 xanthine dehydrogenase NP_697382.1 359644 D 204722 CDS NP_697383.1 23501256 1166012 362117..362863 1 NC_004310.3 identified by similarity to OMNI:CC2617; chaperone XdhC 362863 1166012 BR0351 Brucella suis 1330 chaperone XdhC NP_697383.1 362117 D 204722 CDS NP_697384.1 23501257 1166013 complement(362944..363858) 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 363858 1166013 BR0352 Brucella suis 1330 LysR family transcriptional regulator NP_697384.1 362944 R 204722 CDS NP_697385.1 23501258 1166014 364039..365283 1 NC_004310.3 identified by similarity to GP:15140681; hypothetical protein 365283 1166014 BR0353 Brucella suis 1330 hypothetical protein NP_697385.1 364039 D 204722 CDS NP_697386.1 23501259 1166015 365280..366584 1 NC_004310.3 Catalyzes the deamination of guanine; guanine deaminase 366584 1166015 BR0354 Brucella suis 1330 guanine deaminase NP_697386.1 365280 D 204722 CDS NP_697387.1 23501260 1166016 366664..367950 1 NC_004310.3 identified by similarity to EGAD:40602; match to protein family HMM PF05161; hydroxypyruvate reductase 367950 1166016 BR0355 Brucella suis 1330 hydroxypyruvate reductase NP_697387.1 366664 D 204722 CDS NP_697388.1 23501261 1166017 complement(367931..368089) 1 NC_004310.3 identified by match to protein family HMM PF03597; match to protein family HMM TIGR00847; cbb3-type cytochrome oxidase maturation protein 368089 ccoS 1166017 ccoS Brucella suis 1330 cbb3-type cytochrome oxidase maturation protein NP_697388.1 367931 R 204722 CDS NP_697389.1 23501262 1166018 complement(368086..370344) 1 NC_004310.3 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; nitrogen fixation protein FixI 370344 1166018 BR0357 Brucella suis 1330 nitrogen fixation protein FixI NP_697389.1 368086 R 204722 CDS NP_697390.1 23501263 1166019 complement(370341..370838) 1 NC_004310.3 identified by similarity to EGAD:10086; match to protein family HMM PF05751; nitrogen fixation protein FixH 370838 1166019 BR0358 Brucella suis 1330 nitrogen fixation protein FixH NP_697390.1 370341 R 204722 CDS NP_697391.1 23501264 1166020 complement(370838..372388) 1 NC_004310.3 (Fe-S)-binding protein 372388 1166020 BR0359 Brucella suis 1330 (Fe-S)-binding protein NP_697391.1 370838 R 204722 CDS NP_697392.1 23501265 1166021 complement(372548..373411) 1 NC_004310.3 identified by match to protein family HMM PF00034; match to protein family HMM TIGR00782; cytochrome c oxidase, cbb3-type subunit III 373411 ccoP 1166021 ccoP Brucella suis 1330 cytochrome c oxidase, cbb3-type subunit III NP_697392.1 372548 R 204722 CDS NP_697393.1 23501266 1166022 complement(373404..373562) 1 NC_004310.3 identified by similarity to EGAD:125983; match to protein family HMM PF05545; cytochrome c oxidase, cbb3-type, CcoQ subunit 373562 ccoQ 1166022 ccoQ Brucella suis 1330 cytochrome c oxidase, cbb3-type, CcoQ subunit NP_697393.1 373404 R 204722 CDS NP_697394.1 23501267 1166023 complement(373577..374308) 1 NC_004310.3 CcoO; FixO; cbb3-type cytochrome c oxidase subunit II 374308 ccoO 1166023 ccoO Brucella suis 1330 cbb3-type cytochrome c oxidase subunit II NP_697394.1 373577 R 204722 CDS NP_697395.1 23501268 1166024 complement(374323..375948) 1 NC_004310.3 CcoN; FixN; cbb3-type cytochrome c oxidase subunit I 375948 ccoN 1166024 ccoN Brucella suis 1330 cbb3-type cytochrome c oxidase subunit I NP_697395.1 374323 R 204722 CDS NP_697396.1 23501269 1166025 complement(376166..376624) 1 NC_004310.3 identified by match to protein family HMM PF01475; FUR family transcriptional regulator 376624 1166025 BR0364 Brucella suis 1330 FUR family transcriptional regulator NP_697396.1 376166 R 204722 CDS NP_697397.1 23501270 1166026 376623..376949 1 NC_004310.3 hypothetical protein 376949 1166026 BR0365 Brucella suis 1330 hypothetical protein NP_697397.1 376623 D 204722 CDS NP_697398.1 23501271 1166027 377066..377680 1 NC_004310.3 identified by similarity to GP:13235366; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 377680 1166027 BR0366 Brucella suis 1330 twin-arginine translocation pathway signal sequence domain-containing protein NP_697398.1 377066 D 204722 CDS NP_697399.1 23501272 1166028 complement(377729..379174) 1 NC_004310.3 identified by match to protein family HMM PF00171; aldehyde dehydrogenase 379174 1166028 BR0367 Brucella suis 1330 aldehyde dehydrogenase NP_697399.1 377729 R 204722 CDS NP_697400.1 23501273 1166029 379373..380458 1 NC_004310.3 identified by similarity to EGAD:7337; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM TIGR00589; ada regulatory protein 380458 ada 1166029 ada Brucella suis 1330 ada regulatory protein NP_697400.1 379373 D 204722 CDS NP_697401.1 23501274 1166030 380640..380990 1 NC_004310.3 identified by similarity to GP:15073235; match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 380990 1166030 BR0369 Brucella suis 1330 hypothetical protein NP_697401.1 380640 D 204722 CDS NP_697402.1 23501275 1166031 381327..382370 1 NC_004310.3 identified by similarity to GP:15156192; hypothetical protein 382370 1166031 BR0370 Brucella suis 1330 hypothetical protein NP_697402.1 381327 D 204722 CDS NP_697403.1 23501276 1166033 383821..385068 1 NC_004310.3 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 385068 bacA 1166033 bacA Brucella suis 1330 transport protein NP_697403.1 383821 D 204722 CDS NP_697404.1 23501277 1166034 complement(385107..386105) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5836; hypothetical protein 386105 1166034 BR0373 Brucella suis 1330 hypothetical protein NP_697404.1 385107 R 204722 CDS NP_697405.1 23501278 1166035 386351..387022 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5837; hypothetical protein 387022 1166035 BR0374 Brucella suis 1330 hypothetical protein NP_697405.1 386351 D 204722 CDS NP_697406.1 23501279 1166036 387044..388495 1 NC_004310.3 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 388495 engA 1166036 engA Brucella suis 1330 GTP-binding protein EngA NP_697406.1 387044 D 204722 CDS NP_697407.1 23501280 1166037 388654..389970 1 NC_004310.3 identified by similarity to SP:P04475; molecular chaperone DnaK 389970 1166037 BR0376 Brucella suis 1330 molecular chaperone DnaK NP_697407.1 388654 D 204722 CDS NP_697408.1 23501281 1166038 complement(390060..390185) 1 NC_004310.3 hypothetical protein 390185 1166038 BR0377 Brucella suis 1330 hypothetical protein NP_697408.1 390060 R 204722 CDS NP_697409.1 23501282 1166039 390407..391696 1 NC_004310.3 identified by similarity to GP:14026921; hypothetical protein 391696 1166039 BR0378 Brucella suis 1330 hypothetical protein NP_697409.1 390407 D 204722 CDS NP_697410.1 23501283 1166040 391724..391828 1 NC_004310.3 hypothetical protein 391828 1166040 BR0379 Brucella suis 1330 hypothetical protein NP_697410.1 391724 D 204722 CDS NP_697411.1 23501284 1166041 391858..391983 1 NC_004310.3 hypothetical protein 391983 1166041 BR0380 Brucella suis 1330 hypothetical protein NP_697411.1 391858 D 204722 CDS NP_697412.1 23501285 1166042 391967..392365 1 NC_004310.3 identified by similarity to EGAD:21946; ATP sythase I 392365 1166042 BR0381 Brucella suis 1330 ATP sythase I NP_697412.1 391967 D 204722 CDS NP_697413.1 23501286 1166043 392473..393222 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 393222 atpB 1166043 atpB Brucella suis 1330 ATP synthase F0F1 subunit A NP_697413.1 392473 D 204722 CDS NP_697414.1 23501287 1166044 393290..393517 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 393517 atpE 1166044 atpE Brucella suis 1330 ATP synthase F0F1 subunit C NP_697414.1 393290 D 204722 CDS NP_697415.1 23501288 1166045 393689..394315 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; ATP synthase F0F1 subunit B' 394315 1166045 BR0384 Brucella suis 1330 ATP synthase F0F1 subunit B' NP_697415.1 393689 D 204722 CDS NP_697416.1 23501289 1166046 394326..394805 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 394805 atpF 1166046 atpF Brucella suis 1330 ATP synthase F0F1 subunit B NP_697416.1 394326 D 204722 CDS NP_697417.1 23501290 1166047 complement(394928..395590) 1 NC_004310.3 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 395590 rnhB 1166047 rnhB Brucella suis 1330 ribonuclease HII NP_697417.1 394928 R 204722 CDS NP_697418.1 23501291 1166048 complement(395767..396939) 1 NC_004310.3 identified by similarity to GP:15073771; match to protein family HMM PF04055; hypothetical protein 396939 1166048 BR0387 Brucella suis 1330 hypothetical protein NP_697418.1 395767 R 204722 CDS NP_697419.1 23501292 1166049 397075..397581 1 NC_004310.3 identified by similarity to GP:15155690; hypothetical protein 397581 1166049 BR0388 Brucella suis 1330 hypothetical protein NP_697419.1 397075 D 204722 CDS NP_697420.1 23501293 1166050 complement(397661..397933) 1 NC_004310.3 hypothetical protein 397933 1166050 BR0389 Brucella suis 1330 hypothetical protein NP_697420.1 397661 R 204722 CDS NP_697421.1 23501294 1166051 397923..398030 1 NC_004310.3 hypothetical protein 398030 1166051 BR0390 Brucella suis 1330 hypothetical protein NP_697421.1 397923 D 204722 CDS NP_697422.1 23501295 1166052 complement(398077..398352) 1 NC_004310.3 hypothetical protein 398352 1166052 BR0391 Brucella suis 1330 hypothetical protein NP_697422.1 398077 R 204722 CDS NP_697423.1 23501296 1166053 complement(398424..398657) 1 NC_004310.3 hypothetical protein 398657 1166053 BR0392 Brucella suis 1330 hypothetical protein NP_697423.1 398424 R 204722 CDS NP_697424.1 23501297 1166054 complement(398620..398766) 1 NC_004310.3 hypothetical protein 398766 1166054 BR0393 Brucella suis 1330 hypothetical protein NP_697424.1 398620 R 204722 CDS NP_697425.1 23501298 1166055 complement(398711..399610) 1 NC_004310.3 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 399610 ispE 1166055 ispE Brucella suis 1330 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_697425.1 398711 R 204722 CDS NP_697426.1 23501299 1166056 complement(399640..399861) 1 NC_004310.3 hypothetical protein 399861 1166056 BR0395 Brucella suis 1330 hypothetical protein NP_697426.1 399640 R 204722 CDS NP_697427.1 23501300 1166057 complement(400292..401398) 1 NC_004310.3 identified by match to protein family HMM PF01343; endopeptidase IV 401398 1166057 BR0396 Brucella suis 1330 endopeptidase IV NP_697427.1 400292 R 204722 CDS NP_697428.1 23501301 1166058 complement(401319..402500) 1 NC_004310.3 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter 402500 nhaA 1166058 nhaA Brucella suis 1330 pH-dependent sodium/proton antiporter NP_697428.1 401319 R 204722 CDS NP_697429.1 23501302 1166059 complement(402520..402741) 1 NC_004310.3 hypothetical protein 402741 1166059 BR0398 Brucella suis 1330 hypothetical protein NP_697429.1 402520 R 204722 CDS NP_697430.1 23501303 1166060 complement(402790..403548) 1 NC_004310.3 identified by similarity to GP:15073779; hypothetical protein 403548 1166060 BR0399 Brucella suis 1330 hypothetical protein NP_697430.1 402790 R 204722 CDS NP_697431.1 23501304 1166061 complement(403569..403796) 1 NC_004310.3 identified by similarity to GP:15073778; hypothetical protein 403796 1166061 BR0400 Brucella suis 1330 hypothetical protein NP_697431.1 403569 R 204722 CDS NP_697432.1 23501305 1166062 404059..405081 1 NC_004310.3 identified by match to protein family HMM PF00348; polyprenyl synthetase 405081 1166062 BR0401 Brucella suis 1330 polyprenyl synthetase NP_697432.1 404059 D 204722 CDS NP_697433.1 23501306 1166063 405385..407250 1 NC_004310.3 identified by match to protein family HMM PF00515; TPR domain-containing protein 407250 1166063 BR0402 Brucella suis 1330 TPR domain-containing protein NP_697433.1 405385 D 204722 CDS NP_697434.1 23501307 1166064 407402..408328 1 NC_004310.3 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 408328 glyQ 1166064 glyQ Brucella suis 1330 glycyl-tRNA synthetase subunit alpha NP_697434.1 407402 D 204722 CDS NP_697435.1 23501308 1166065 408447..410780 1 NC_004310.3 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 410780 glyS 1166065 glyS Brucella suis 1330 glycyl-tRNA synthetase subunit beta NP_697435.1 408447 D 204722 CDS NP_697436.1 23501309 1166066 410919..411890 1 NC_004310.3 identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC family protein 411890 1166066 BR0405 Brucella suis 1330 Sua5/YciO/YrdC family protein NP_697436.1 410919 D 204722 CDS NP_697437.1 23501310 1166067 411916..413328 1 NC_004310.3 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD-binding oxidoreductase 413328 1166067 BR0406 Brucella suis 1330 FAD-binding oxidoreductase NP_697437.1 411916 D 204722 CDS NP_697438.1 23501311 1166068 complement(413366..413683) 1 NC_004310.3 identified by similarity to OMNI:VCA0423; match to protein family HMM PF05016; hypothetical protein 413683 1166068 BR0407 Brucella suis 1330 hypothetical protein NP_697438.1 413366 R 204722 CDS NP_697439.1 23501312 1166069 complement(413680..413940) 1 NC_004310.3 identified by similarity to GP:3337067; hypothetical protein 413940 1166069 BR0408 Brucella suis 1330 hypothetical protein NP_697439.1 413680 R 204722 CDS NP_697440.1 23501313 1166070 complement(414049..414222) 1 NC_004310.3 hypothetical protein 414222 1166070 BR0409 Brucella suis 1330 hypothetical protein NP_697440.1 414049 R 204722 CDS NP_697441.1 23501314 1166071 414251..414817 1 NC_004310.3 identified by similarity to GP:15155604; hypothetical protein 414817 1166071 BR0410 Brucella suis 1330 hypothetical protein NP_697441.1 414251 D 204722 CDS NP_697442.1 23501315 1166072 complement(414960..415712) 1 NC_004310.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 415712 1166072 BR0411 Brucella suis 1330 enoyl-CoA hydratase NP_697442.1 414960 R 204722 CDS NP_697443.1 23501316 1166073 complement(415715..417493) 1 NC_004310.3 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase 417493 1166073 BR0412 Brucella suis 1330 acyl-CoA dehydrogenase NP_697443.1 415715 R 204722 CDS NP_697444.1 23501317 1166075 complement(418974..420257) 1 NC_004310.3 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 420257 purD 1166075 purD Brucella suis 1330 phosphoribosylamine--glycine ligase NP_697444.1 418974 R 204722 CDS NP_697445.1 23501318 1166076 420402..421403 1 NC_004310.3 UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 421403 ubiA 1166076 ubiA Brucella suis 1330 4-hydroxybenzoate polyprenyltransferase NP_697445.1 420402 D 204722 CDS NP_697446.1 23501319 1166077 complement(421443..422069) 1 NC_004310.3 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase 422069 pdxH 1166077 pdxH Brucella suis 1330 pyridoxamine 5'-phosphate oxidase NP_697446.1 421443 R 204722 CDS NP_697447.1 23501320 1166078 422328..422798 1 NC_004310.3 identified by similarity to GP:14026958; hypothetical protein 422798 1166078 BR0417 Brucella suis 1330 hypothetical protein NP_697447.1 422328 D 204722 CDS NP_697448.1 23501321 1166079 422943..423884 1 NC_004310.3 identified by match to protein family HMM PF00226; match to protein family HMM PF01556; molecular chaperone DnaJ 423884 1166079 BR0418 Brucella suis 1330 molecular chaperone DnaJ NP_697448.1 422943 D 204722 CDS NP_697449.1 23501322 1166080 complement(423888..423995) 1 NC_004310.3 hypothetical protein 423995 1166080 BR0419 Brucella suis 1330 hypothetical protein NP_697449.1 423888 R 204722 CDS NP_697450.1 23501323 1166081 424028..424846 1 NC_004310.3 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 424846 fabI-1 1166081 fabI-1 Brucella suis 1330 enoyl-ACP reductase NP_697450.1 424028 D 204722 CDS NP_697451.1 23501324 1166083 complement(425676..425855) 1 NC_004310.3 hypothetical protein 425855 1166083 BR0422 Brucella suis 1330 hypothetical protein NP_697451.1 425676 R 204722 CDS NP_697452.1 23501325 1166085 complement(426109..426258) 1 NC_004310.3 hypothetical protein 426258 1166085 BR0424 Brucella suis 1330 hypothetical protein NP_697452.1 426109 R 204722 CDS NP_697453.1 23501326 1166086 426514..426693 1 NC_004310.3 identified by similarity to GP:15160282; hypothetical protein 426693 1166086 BR0425 Brucella suis 1330 hypothetical protein NP_697453.1 426514 D 204722 CDS NP_697454.1 23501327 1166087 426788..427450 1 NC_004310.3 identified by similarity to GP:14027592; match to protein family HMM PF04028; hypothetical protein 427450 1166087 BR0426 Brucella suis 1330 hypothetical protein NP_697454.1 426788 D 204722 CDS NP_697455.1 23501328 1166088 complement(427595..427846) 1 NC_004310.3 identified by similarity to GP:15073831; hypothetical protein 427846 1166088 BR0427 Brucella suis 1330 hypothetical protein NP_697455.1 427595 R 204722 CDS NP_697456.1 23501329 1166089 428122..429216 1 NC_004310.3 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 429216 aroC 1166089 aroC Brucella suis 1330 chorismate synthase NP_697456.1 428122 D 204722 CDS NP_697457.1 23501330 1166090 429352..430467 1 NC_004310.3 identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00506; 3,4-dihydroxy-2-butanone-4-phosphate synthase 430467 ribAB 1166090 ribAB Brucella suis 1330 3,4-dihydroxy-2-butanone-4-phosphate synthase NP_697457.1 429352 D 204722 CDS NP_697458.1 23501331 1166091 430620..431633 1 NC_004310.3 identified by match to protein family HMM PF00850; histone deacetylase 431633 1166091 BR0430 Brucella suis 1330 histone deacetylase NP_697458.1 430620 D 204722 CDS NP_697459.1 23501332 1166092 431638..431892 1 NC_004310.3 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 431892 xseB 1166092 xseB Brucella suis 1330 exodeoxyribonuclease VII small subunit NP_697459.1 431638 D 204722 CDS NP_697460.1 23501333 1166093 complement(431899..432417) 1 NC_004310.3 identified by match to protein family HMM PF00597; dedA family protein 432417 1166093 BR0432 Brucella suis 1330 dedA family protein NP_697460.1 431899 R 204722 CDS NP_697461.1 23501334 1166094 complement(432659..432919) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3629; match to protein family HMM PF04226; transglycosylase-associated protein 432919 1166094 BR0433 Brucella suis 1330 transglycosylase-associated protein NP_697461.1 432659 R 204722 CDS NP_697462.1 23501335 1166095 433082..433633 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3630; hypothetical protein 433633 1166095 BR0434 Brucella suis 1330 hypothetical protein NP_697462.1 433082 D 204722 CDS NP_697463.1 23501336 1166096 433837..434709 1 NC_004310.3 identified by similarity to OMNI:CC3178; match to protein family HMM PF02678; match to protein family HMM PF05726; pirin 434709 1166096 BR0435 Brucella suis 1330 pirin NP_697463.1 433837 D 204722 CDS NP_697464.1 23501337 1166097 434852..436783 1 NC_004310.3 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 436783 dxs 1166097 dxs Brucella suis 1330 1-deoxy-D-xylulose-5-phosphate synthase NP_697464.1 434852 D 204722 CDS NP_697465.1 23501338 1166098 436789..437550 1 NC_004310.3 identified by similarity to EGAD:20008; match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 437550 tlyA 1166098 tlyA Brucella suis 1330 hemolysin A NP_697465.1 436789 D 204722 CDS NP_697466.1 23501339 1166099 437547..438794 1 NC_004310.3 RNA methyltransferase 438794 1166099 BR0438 Brucella suis 1330 RNA methyltransferase NP_697466.1 437547 D 204722 CDS NP_697467.1 23501340 1166100 complement(438930..439532) 1 NC_004310.3 identified by similarity to GP:15074050; match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein 439532 1166100 BR0439 Brucella suis 1330 hypothetical protein NP_697467.1 438930 R 204722 CDS NP_697468.1 23501341 1166101 439662..440027 1 NC_004310.3 identified by similarity to GP:15157092; hypothetical protein 440027 1166101 BR0440 Brucella suis 1330 hypothetical protein NP_697468.1 439662 D 204722 CDS NP_697469.1 23501342 1166102 440214..441428 1 NC_004310.3 identified by match to protein family HMM PF01476; LysM domain-containing protein 441428 1166102 BR0441 Brucella suis 1330 LysM domain-containing protein NP_697469.1 440214 D 204722 CDS NP_697470.1 23501343 1166103 441631..443517 1 NC_004310.3 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 443517 1166103 BR0442 Brucella suis 1330 ABC transporter ATP-binding/permease NP_697470.1 441631 D 204722 CDS NP_697471.1 23501344 1166104 443622..444320 1 NC_004310.3 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 444320 1166104 BR0443 Brucella suis 1330 phosphatidylserine decarboxylase NP_697471.1 443622 D 204722 CDS NP_697472.1 23501345 1166105 444325..445161 1 NC_004310.3 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 445161 pssA 1166105 pssA Brucella suis 1330 CDP-diacylglycerol--serine O-phosphatidyltransferase NP_697472.1 444325 D 204722 CDS NP_697473.1 23501346 1166106 complement(445246..445986) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 445986 1166106 BR0445 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_697473.1 445246 R 204722 CDS NP_697474.1 23501347 1166107 complement(446055..447512) 1 NC_004310.3 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 447512 purF 1166107 purF Brucella suis 1330 amidophosphoribosyltransferase NP_697474.1 446055 R 204722 CDS NP_697475.1 23501348 1166108 447489..447731 1 NC_004310.3 hypothetical protein 447731 1166108 BR0447 Brucella suis 1330 hypothetical protein NP_697475.1 447489 D 204722 CDS NP_697476.1 23501349 1166109 complement(447827..448405) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6179; match to protein family HMM PF02674; colicin V production protein 448405 1166109 BR0448 Brucella suis 1330 colicin V production protein NP_697476.1 447827 R 204722 CDS NP_697477.1 23501350 1166110 complement(448531..449934) 1 NC_004310.3 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 449934 radA 1166110 radA Brucella suis 1330 DNA repair protein RadA NP_697477.1 448531 R 204722 CDS NP_697478.1 23501351 1166111 complement(449962..451467) 1 NC_004310.3 unwinds double stranded DNA; replicative DNA helicase 451467 dnaB 1166111 dnaB Brucella suis 1330 replicative DNA helicase NP_697478.1 449962 R 204722 CDS NP_697479.1 23501352 1166112 complement(451666..452946) 1 NC_004310.3 identified by similarity to SP:P30010; match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase 452946 cfa 1166112 cfa Brucella suis 1330 cyclopropane-fatty-acyl-phospholipid synthase NP_697479.1 451666 R 204722 CDS NP_697480.1 23501353 1166113 complement(453320..453889) 1 NC_004310.3 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 453889 rplI 1166113 rplI Brucella suis 1330 50S ribosomal protein L9 NP_697480.1 453320 R 204722 CDS NP_697481.1 23501354 1166114 complement(453919..454890) 1 NC_004310.3 identified by similarity to GP:15074068; hypothetical protein 454890 1166114 BR0453 Brucella suis 1330 hypothetical protein NP_697481.1 453919 R 204722 CDS NP_697482.1 23501355 1166115 complement(455041..455289) 1 NC_004310.3 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 455289 rpsR 1166115 rpsR Brucella suis 1330 30S ribosomal protein S18 NP_697482.1 455041 R 204722 CDS NP_697483.1 23501356 1166116 complement(455292..455738) 1 NC_004310.3 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 455738 rpsF 1166116 rpsF Brucella suis 1330 30S ribosomal protein S6 NP_697483.1 455292 R 204722 CDS NP_697484.1 23501357 1166117 complement(455763..456122) 1 NC_004310.3 identified by similarity to OMNI:VC2163; hypothetical protein 456122 1166117 BR0456 Brucella suis 1330 hypothetical protein NP_697484.1 455763 R 204722 CDS NP_697485.1 23501358 1166118 456144..457088 1 NC_004310.3 identified by similarity to EGAD:97846; match to protein family HMM PF00698; match to protein family HMM TIGR00128; ACP S-malonyltransferase 457088 fabD 1166118 fabD Brucella suis 1330 ACP S-malonyltransferase NP_697485.1 456144 D 204722 CDS NP_697486.1 23501359 1166119 457158..457895 1 NC_004310.3 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 457895 fabG 1166119 fabG Brucella suis 1330 3-ketoacyl-ACP reductase NP_697486.1 457158 D 204722 CDS NP_697487.1 23501360 1166120 458169..458405 1 NC_004310.3 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 458405 acpP 1166120 acpP Brucella suis 1330 acyl carrier protein NP_697487.1 458169 D 204722 CDS NP_697488.1 23501361 1166121 458409..458672 1 NC_004310.3 hypothetical protein 458672 1166121 BR0460 Brucella suis 1330 hypothetical protein NP_697488.1 458409 D 204722 CDS NP_697489.1 23501362 1166122 458729..459991 1 NC_004310.3 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 459991 fabF 1166122 fabF Brucella suis 1330 3-oxoacyl-ACP synthase NP_697489.1 458729 D 204722 CDS NP_697490.1 23501363 1166123 460216..461454 1 NC_004310.3 identified by similarity to GP:15074077; match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 461454 1166123 BR0462 Brucella suis 1330 hypothetical protein NP_697490.1 460216 D 204722 CDS NP_697491.1 23501364 1166124 461640..462539 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6198; match to protein family HMM PF03755; match to protein family HMM TIGR00255; hypothetical protein 462539 1166124 BR0463 Brucella suis 1330 hypothetical protein NP_697491.1 461640 D 204722 CDS NP_697492.1 23501365 1166125 462548..463210 1 NC_004310.3 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 463210 gmk 1166125 gmk Brucella suis 1330 guanylate kinase NP_697492.1 462548 D 204722 CDS NP_697493.1 23501366 1166126 complement(463237..464649) 1 NC_004310.3 identified by similarity to EGAD:30245; match to protein family HMM PF01523; tldD protein 464649 1166126 BR0465 Brucella suis 1330 tldD protein NP_697493.1 463237 R 204722 CDS NP_697494.1 23501367 1166127 complement(464791..465387) 1 NC_004310.3 identified by similarity to GP:15073834; hypothetical protein 465387 1166127 BR0466 Brucella suis 1330 hypothetical protein NP_697494.1 464791 R 204722 CDS NP_697495.1 23501368 1166128 465851..466705 1 NC_004310.3 identified by similarity to EGAD:8295; match to protein family HMM PF00116; match to protein family HMM PF02790; cytochrome c oxidase subunit II 466705 coxB 1166128 coxB Brucella suis 1330 cytochrome c oxidase subunit II NP_697495.1 465851 D 204722 CDS NP_697496.1 23501369 1166129 466843..468501 1 NC_004310.3 identified by similarity to EGAD:5976; match to protein family HMM PF00115; cytochrome c oxidase subunit I 468501 coxA 1166129 coxA Brucella suis 1330 cytochrome c oxidase subunit I NP_697496.1 466843 D 204722 CDS NP_697497.1 23501370 1166130 468729..469676 1 NC_004310.3 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 469676 ctaB 1166130 ctaB Brucella suis 1330 protoheme IX farnesyltransferase NP_697497.1 468729 D 204722 CDS NP_697498.1 23501371 1166131 469676..469861 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5908; hypothetical protein 469861 1166131 BR0470 Brucella suis 1330 hypothetical protein NP_697498.1 469676 D 204722 CDS NP_697499.1 23501372 1166132 469881..470486 1 NC_004310.3 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 470486 ctaG 1166132 ctaG Brucella suis 1330 cytochrome C oxidase assembly protein NP_697499.1 469881 D 204722 CDS NP_697500.1 23501373 1166133 470695..471573 1 NC_004310.3 identified by match to protein family HMM PF00510; cytochrome c oxidase subunit III 471573 coxC 1166133 coxC Brucella suis 1330 cytochrome c oxidase subunit III NP_697500.1 470695 D 204722 CDS NP_697501.1 23501374 1166134 471687..472070 1 NC_004310.3 identified by similarity to GP:14026992; hypothetical protein 472070 1166134 BR0473 Brucella suis 1330 hypothetical protein NP_697501.1 471687 D 204722 CDS NP_697502.1 23501375 1166135 472067..472816 1 NC_004310.3 identified by match to protein family HMM PF02104; SurF1 family protein 472816 1166135 BR0474 Brucella suis 1330 SurF1 family protein NP_697502.1 472067 D 204722 CDS NP_697503.1 23501376 1166136 472847..473965 1 NC_004310.3 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 473965 ispH 1166136 ispH Brucella suis 1330 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_697503.1 472847 D 204722 CDS NP_697504.1 23501377 1166137 473971..474951 1 NC_004310.3 catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 474951 thrB 1166137 thrB Brucella suis 1330 homoserine kinase NP_697504.1 473971 D 204722 CDS NP_697505.1 23501378 1166138 474948..475412 1 NC_004310.3 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 475412 rnhA 1166138 rnhA Brucella suis 1330 ribonuclease H NP_697505.1 474948 D 204722 CDS NP_697506.1 23501379 1166139 complement(475442..475927) 1 NC_004310.3 identified by match to protein family HMM PF00578; ahpC/TSA family protein 475927 1166139 BR0478 Brucella suis 1330 ahpC/TSA family protein NP_697506.1 475442 R 204722 CDS NP_697507.1 23501380 1166140 complement(476107..476907) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5920; hypothetical protein 476907 1166140 BR0479 Brucella suis 1330 hypothetical protein NP_697507.1 476107 R 204722 CDS NP_697508.1 23501381 1166141 477042..477644 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5921; match to protein family HMM PF02622; hypothetical protein 477644 1166141 BR0480 Brucella suis 1330 hypothetical protein NP_697508.1 477042 D 204722 CDS NP_697509.1 23501382 1166142 complement(477742..480636) 1 NC_004310.3 identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein 480636 1166142 BR0481 Brucella suis 1330 sensory box protein NP_697509.1 477742 R 204722 CDS NP_697510.1 23501383 1166143 complement(480633..481253) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 481253 1166143 BR0482 Brucella suis 1330 acetyltransferase NP_697510.1 480633 R 204722 CDS NP_697511.1 23501384 1166144 complement(481424..482716) 1 NC_004310.3 identified by similarity to OMNI:NTL01BH2408; match to protein family HMM PF00675; match to protein family HMM PF05193; processing protease 482716 1166144 BR0483 Brucella suis 1330 processing protease NP_697511.1 481424 R 204722 CDS NP_697512.1 23501385 1166145 complement(482770..484161) 1 NC_004310.3 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 484161 thrC 1166145 thrC Brucella suis 1330 threonine synthase NP_697512.1 482770 R 204722 CDS NP_697513.1 23501386 1166146 complement(484241..484432) 1 NC_004310.3 hypothetical protein 484432 1166146 BR0485 Brucella suis 1330 hypothetical protein NP_697513.1 484241 R 204722 CDS NP_697514.1 23501387 1166147 484583..485161 1 NC_004310.3 lipoprotein 485161 1166147 BR0486 Brucella suis 1330 lipoprotein NP_697514.1 484583 D 204722 CDS NP_697515.1 23501388 1166148 485475..487109 1 NC_004310.3 identified by similarity to OMNI:NTL03PA02200; match to protein family HMM PF00563; diguanylate phosphodiesterase 487109 1166148 BR0487 Brucella suis 1330 diguanylate phosphodiesterase NP_697515.1 485475 D 204722 CDS NP_697516.1 23501389 1166149 487238..487423 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1736; hypothetical protein 487423 1166149 BR0488 Brucella suis 1330 hypothetical protein NP_697516.1 487238 D 204722 CDS NP_697517.1 23501390 1166150 complement(487465..488151) 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 488151 1166150 BR0489 Brucella suis 1330 HAD superfamily hydrolase NP_697517.1 487465 R 204722 CDS NP_697518.1 23501391 1166151 complement(488299..490089) 1 NC_004310.3 identified by match to protein family HMM PF00654; voltage gated chloride channel family protein 490089 1166151 BR0490 Brucella suis 1330 voltage gated chloride channel family protein NP_697518.1 488299 R 204722 CDS NP_697519.1 23501392 1166152 490426..491559 1 NC_004310.3 identified by similarity to EGAD:154344; match to protein family HMM PF01555; modification methylase BabI 491559 babI 1166152 babI Brucella suis 1330 modification methylase BabI NP_697519.1 490426 D 204722 CDS NP_697520.1 23501393 1166153 complement(491642..492259) 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD superfamily hydrolase 492259 1166153 BR0492 Brucella suis 1330 HAD superfamily hydrolase NP_697520.1 491642 R 204722 CDS NP_697521.1 23501394 1166154 complement(492256..493332) 1 NC_004310.3 identified by similarity to EGAD:19424; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase 493332 mutY 1166154 mutY Brucella suis 1330 A/G-specific adenine glycosylase NP_697521.1 492256 R 204722 CDS NP_697522.1 23501395 1166155 493606..494133 1 NC_004310.3 identified by similarity to GP:15073860; hypothetical protein 494133 1166155 BR0494 Brucella suis 1330 hypothetical protein NP_697522.1 493606 D 204722 CDS NP_697523.1 23501396 1166156 494151..494324 1 NC_004310.3 hypothetical protein 494324 1166156 BR0495 Brucella suis 1330 hypothetical protein NP_697523.1 494151 D 204722 CDS NP_697524.1 23501397 1166157 494371..495024 1 NC_004310.3 identified by similarity to GP:15155781; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 495024 1166157 BR0496 Brucella suis 1330 twin-arginine translocation pathway signal sequence domain-containing protein NP_697524.1 494371 D 204722 CDS NP_697525.1 23501398 1166158 495103..498561 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5933; match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM TIGR02168; SMC family protein 498561 1166158 BR0497 Brucella suis 1330 SMC family protein NP_697525.1 495103 D 204722 CDS NP_697526.1 23501399 1166159 498584..499477 1 NC_004310.3 identified by similarity to SP:P13512; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cobalt-zinc-cadmium resistance protein 499477 1166159 BR0498 Brucella suis 1330 cobalt-zinc-cadmium resistance protein NP_697526.1 498584 D 204722 CDS NP_697527.1 23501400 1166160 complement(499587..499928) 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 499928 1166160 BR0499 Brucella suis 1330 glyoxalase NP_697527.1 499587 R 204722 CDS NP_697528.1 23501401 1166161 500192..502855 1 NC_004310.3 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 502855 ppdK 1166161 ppdK Brucella suis 1330 pyruvate phosphate dikinase NP_697528.1 500192 D 204722 CDS NP_697529.1 23501402 1166163 complement(504131..504277) 1 NC_004310.3 hypothetical protein 504277 1166163 BR0502 Brucella suis 1330 hypothetical protein NP_697529.1 504131 R 204722 CDS NP_697530.1 23501403 1166164 complement(504274..504603) 1 NC_004310.3 hypothetical protein 504603 1166164 BR0503 Brucella suis 1330 hypothetical protein NP_697530.1 504274 R 204722 CDS NP_697531.1 23501404 1166165 504887..505675 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5941; hypothetical protein 505675 1166165 BR0504 Brucella suis 1330 hypothetical protein NP_697531.1 504887 D 204722 CDS NP_697532.1 23501405 1166166 complement(505676..506581) 1 NC_004310.3 identified by match to protein family HMM PF00753; metallo-beta-lactamase 506581 1166166 BR0505 Brucella suis 1330 metallo-beta-lactamase NP_697532.1 505676 R 204722 CDS NP_697533.1 23501406 1166167 506782..507381 1 NC_004310.3 identified by match to protein family HMM PF02632; BioY family protein 507381 1166167 BR0506 Brucella suis 1330 BioY family protein NP_697533.1 506782 D 204722 CDS NP_697534.1 23501407 1166168 507535..508044 1 NC_004310.3 catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 508044 1166168 BR0507 Brucella suis 1330 ureidoglycolate hydrolase NP_697534.1 507535 D 204722 CDS NP_697535.1 23501408 1166169 508056..508412 1 NC_004310.3 identified by similarity to GP:15157490; match to protein family HMM PF00576; hypothetical protein 508412 1166169 BR0508 Brucella suis 1330 hypothetical protein NP_697535.1 508056 D 204722 CDS NP_697536.1 23501409 1166170 508483..509319 1 NC_004310.3 identified by similarity to GP:15157607; hypothetical protein 509319 1166170 BR0509 Brucella suis 1330 hypothetical protein NP_697536.1 508483 D 204722 CDS NP_697537.1 23501410 1166171 509856..511724 1 NC_004310.3 identified by similarity to GP:6009656; match to protein family HMM PF02719; epimerase 511724 1166171 BR0510 Brucella suis 1330 epimerase NP_697537.1 509856 D 204722 CDS NP_697538.1 23501411 1166172 complement(511711..512718) 1 NC_004310.3 identified by match to protein family HMM PF00953; glycosyl transferase group 4 family protein 512718 1166172 BR0511 Brucella suis 1330 glycosyl transferase group 4 family protein NP_697538.1 511711 R 204722 CDS YP_089629.1 52430457 1166175 join(513927..514499,514502..514870) 1 NC_004310.3 identified by similarity to GB:CAE42096.1; ISBm3, transposase, programmed frameshift 514870 1166175 BR0513 Brucella suis 1330 ISBm3, transposase, programmed frameshift YP_089629.1 513927 D 204722 CDS YP_089630.1 52430458 1166176 514927..515157 1 NC_004310.3 identified by similarity to OMNI:CC1206; transposase, interruption-C 515157 1166176 BR0514 Brucella suis 1330 transposase, interruption-C YP_089630.1 514927 D 204722 CDS NP_697539.1 23501412 1166179 complement(516587..517366) 1 NC_004310.3 identified by match to protein family HMM PF00551; formyltransferase 517366 1166179 BR0517 Brucella suis 1330 formyltransferase NP_697539.1 516587 R 204722 CDS NP_697540.1 23501413 1166180 complement(517393..518247) 1 NC_004310.3 identified by similarity to GP:4071215; wbkB protein 518247 wbkB 1166180 wbkB Brucella suis 1330 wbkB protein NP_697540.1 517393 R 204722 CDS NP_697541.1 23501414 1166181 complement(518244..519002) 1 NC_004310.3 identified by similarity to SP:Q56903; match to protein family HMM PF00005; O-antigen export system ATP-binding protein RfbE 519002 rfbE 1166181 rfbE Brucella suis 1330 O-antigen export system ATP-binding protein RfbE NP_697541.1 518244 R 204722 CDS NP_697542.1 23501415 1166182 complement(518999..519781) 1 NC_004310.3 identified by similarity to SP:Q56902; match to protein family HMM PF01061; O-antigen export system permease RfbD 519781 rfbD 1166182 rfbD Brucella suis 1330 O-antigen export system permease RfbD NP_697542.1 518999 R 204722 CDS NP_697543.1 23501416 1166183 complement(519796..520899) 1 NC_004310.3 identified by similarity to EGAD:15706; match to protein family HMM PF01041; perosamine synthase 520899 1166183 BR0521 Brucella suis 1330 perosamine synthase NP_697543.1 519796 R 204722 CDS NP_697544.1 23501417 1166184 complement(520907..521995) 1 NC_004310.3 identified by similarity to EGAD:11583; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase 521995 gmd 1166184 gmd Brucella suis 1330 GDP-mannose 4,6-dehydratase NP_697544.1 520907 R 204722 CDS NP_697545.1 23501418 1166185 522514..522942 1 NC_004310.3 identified by similarity to GP:4071219; ISBm1, transposase orfA 522942 1166185 BR0523 Brucella suis 1330 ISBm1, transposase orfA NP_697545.1 522514 D 204722 CDS YP_089631.1 52430459 1166186 522861..523235 1 NC_004310.3 identified by similarity to GP:4071222; ISBm1, transposase orfB, interruption-N 523235 1166186 BR0524 Brucella suis 1330 ISBm1, transposase orfB, interruption-N YP_089631.1 522861 D 204722 CDS NP_697546.1 23501419 1166188 524151..524462 1 NC_004310.3 identified by similarity to EGAD:46813; IS711, transposase orfA 524462 1166188 BR0526 Brucella suis 1330 IS711, transposase orfA NP_697546.1 524151 D 204722 CDS NP_697547.1 23501420 1166189 524494..524886 1 NC_004310.3 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 524886 1166189 BR0527 Brucella suis 1330 IS711, transposase orfB NP_697547.1 524494 D 204722 CDS YP_089632.1 52430460 1166190 524887..525126 1 NC_004310.3 identified by similarity to GP:4071222; ISBm1, transposase orfB, interruption-C 525126 1166190 BR0528 Brucella suis 1330 ISBm1, transposase orfB, interruption-C YP_089632.1 524887 D 204722 CDS NP_697548.1 23501421 1166191 525257..526375 1 NC_004310.3 identified by match to protein family HMM PF00534; mannosyltransferase 526375 1166191 BR0529 Brucella suis 1330 mannosyltransferase NP_697548.1 525257 D 204722 CDS NP_697549.1 23501422 1166192 526433..526801 1 NC_004310.3 identified by similarity to EGAD:36179; IS5 family transposase orfA 526801 1166192 BR0530 Brucella suis 1330 IS5 family transposase orfA NP_697549.1 526433 D 204722 CDS NP_697550.1 23501423 1166193 526897..527238 1 NC_004310.3 identified by similarity to GP:482819; IS5 family transposase orfB 527238 1166193 BR0531 Brucella suis 1330 IS5 family transposase orfB NP_697550.1 526897 D 204722 CDS NP_697551.1 23501424 1166195 528047..528475 1 NC_004310.3 identified by similarity to GP:4071219; ISBm1, transposase orfA 528475 1166195 BR0533 Brucella suis 1330 ISBm1, transposase orfA NP_697551.1 528047 D 204722 CDS NP_697552.1 23501425 1166196 528394..528810 1 NC_004310.3 identified by similarity to GP:4071222; match to protein family HMM PF01609; ISBm1, transposase orfB 528810 1166196 BR0534 Brucella suis 1330 ISBm1, transposase orfB NP_697552.1 528394 D 204722 CDS NP_697553.1 23501426 1166199 529702..531039 1 NC_004310.3 identified by similarity to EGAD:8806; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 531039 1166199 BR0537 Brucella suis 1330 phosphomannomutase NP_697553.1 529702 D 204722 CDS NP_697554.1 23501427 1166200 531064..532488 1 NC_004310.3 identified by similarity to EGAD:97081; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase 532488 1166200 BR0538 Brucella suis 1330 mannose-1-phosphate guanylyltransferase NP_697554.1 531064 D 204722 CDS NP_697555.1 23501428 1166201 532521..533693 1 NC_004310.3 identified by similarity to SP:P29954; mannose-6-phosphate isomerase 533693 manA 1166201 manA Brucella suis 1330 mannose-6-phosphate isomerase NP_697555.1 532521 D 204722 CDS NP_697556.1 23501429 1166202 533776..534885 1 NC_004310.3 identified by similarity to GP:3249553; match to protein family HMM PF00534; group 1 glycosyl transferase 534885 1166202 BR0540 Brucella suis 1330 group 1 glycosyl transferase NP_697556.1 533776 D 204722 CDS NP_697557.1 23501430 1166203 complement(535366..535578) 1 NC_004310.3 hypothetical protein 535578 1166203 BR0541 Brucella suis 1330 hypothetical protein NP_697557.1 535366 R 204722 CDS NP_697558.1 23501431 1166204 535577..537112 1 NC_004310.3 identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein 537112 rbsA-1 1166204 rbsA-1 Brucella suis 1330 ribose ABC transporter ATP-binding protein NP_697558.1 535577 D 204722 CDS NP_697559.1 23501432 1166205 537133..538134 1 NC_004310.3 identified by similarity to SP:P36948; match to protein family HMM PF02653; ribose ABC transporter permease 538134 rbsC-1 1166205 rbsC-1 Brucella suis 1330 ribose ABC transporter permease NP_697559.1 537133 D 204722 CDS NP_697560.1 23501433 1166206 538213..539175 1 NC_004310.3 identified by similarity to SP:P02926; match to protein family HMM PF00532; ribose ABC transporter periplasmic D-ribose-binding protein 539175 rbsB-1 1166206 rbsB-1 Brucella suis 1330 ribose ABC transporter periplasmic D-ribose-binding protein NP_697560.1 538213 D 204722 CDS NP_697561.1 23501434 1166207 539233..540285 1 NC_004310.3 identified by similarity to GP:15075918; hypothetical protein 540285 1166207 BR0545 Brucella suis 1330 hypothetical protein NP_697561.1 539233 D 204722 CDS NP_697562.1 23501435 1166208 540293..541465 1 NC_004310.3 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 541465 1166208 BR0546 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_697562.1 540293 D 204722 CDS NP_697563.1 23501436 1166209 complement(541507..542814) 1 NC_004310.3 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 542814 xylA 1166209 xylA Brucella suis 1330 xylose isomerase NP_697563.1 541507 R 204722 CDS NP_697564.1 23501437 1166210 complement(542861..544312) 1 NC_004310.3 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase 544312 xylB 1166210 xylB Brucella suis 1330 xylulokinase NP_697564.1 542861 R 204722 CDS NP_697565.1 23501438 1166211 complement(544345..545376) 1 NC_004310.3 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcription regulator 545376 1166211 BR0549 Brucella suis 1330 LacI family transcription regulator NP_697565.1 544345 R 204722 CDS NP_697566.1 23501439 1166212 complement(545638..546708) 1 NC_004310.3 identified by match to protein family HMM PF00165; AraC family transcriptional regulator 546708 1166212 BR0550 Brucella suis 1330 AraC family transcriptional regulator NP_697566.1 545638 R 204722 CDS NP_697567.1 23501440 1166213 complement(547080..547187) 1 NC_004310.3 hypothetical protein 547187 1166213 BR0551 Brucella suis 1330 hypothetical protein NP_697567.1 547080 R 204722 CDS NP_697568.1 23501441 1166214 complement(547247..548710) 1 NC_004310.3 catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase 548710 betB 1166214 betB Brucella suis 1330 betaine aldehyde dehydrogenase NP_697568.1 547247 R 204722 CDS NP_697569.1 23501442 1166215 complement(548896..550545) 1 NC_004310.3 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase 550545 betA 1166215 betA Brucella suis 1330 choline dehydrogenase NP_697569.1 548896 R 204722 CDS NP_697570.1 23501443 1166216 complement(550548..551144) 1 NC_004310.3 HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI 551144 betI 1166216 betI Brucella suis 1330 transcriptional regulator BetI NP_697570.1 550548 R 204722 CDS NP_697571.1 23501444 1166217 551335..552357 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6007; hypothetical protein 552357 1166217 BR0555 Brucella suis 1330 hypothetical protein NP_697571.1 551335 D 204722 CDS NP_697572.1 23501445 1166218 552402..552872 1 NC_004310.3 identified by match to protein family HMM PF01272; transcription elongation factor GreA domain-containing protein 552872 1166218 BR0556 Brucella suis 1330 transcription elongation factor GreA domain-containing protein NP_697572.1 552402 D 204722 CDS NP_697573.1 23501446 1166219 complement(552869..553258) 1 NC_004310.3 identified by similarity to EGAD:69439; match to protein family HMM PF05012; match to protein family HMM TIGR01550; death-on-curing family protein 553258 1166219 BR0557 Brucella suis 1330 death-on-curing family protein NP_697573.1 552869 R 204722 CDS NP_697574.1 23501447 1166220 complement(553255..553485) 1 NC_004310.3 identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; AbrB family transcriptional regulator 553485 1166220 BR0558 Brucella suis 1330 AbrB family transcriptional regulator NP_697574.1 553255 R 204722 CDS NP_697575.1 23501448 1166221 complement(553546..554538) 1 NC_004310.3 identified by similarity to GP:15620053; match to protein family HMM PF01544; magnesium/cobalt transporter CorA 554538 1166221 BR0559 Brucella suis 1330 magnesium/cobalt transporter CorA NP_697575.1 553546 R 204722 CDS NP_697576.1 23501449 1166222 554694..555707 1 NC_004310.3 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 555707 1166222 BR0560 Brucella suis 1330 GntR family transcriptional regulator NP_697576.1 554694 D 204722 CDS NP_697577.1 23501450 1166223 555529..556677 1 NC_004310.3 cyanate transport system protein CynX 556677 1166223 BR0561 Brucella suis 1330 cyanate transport system protein CynX NP_697577.1 555529 D 204722 CDS NP_697578.1 23501451 1166224 complement(556734..557096) 1 NC_004310.3 identified by similarity to GP:15073896; hypothetical protein 557096 1166224 BR0562 Brucella suis 1330 hypothetical protein NP_697578.1 556734 R 204722 CDS NP_697579.1 23501452 1166225 557432..558943 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6012; match to protein family HMM PF05872; hypothetical protein 558943 1166225 BR0563 Brucella suis 1330 hypothetical protein NP_697579.1 557432 D 204722 CDS NP_697580.1 23501453 1166226 complement(559141..559857) 1 NC_004310.3 identified by similarity to GP:15141233; match to protein family HMM PF03734; match to protein family HMM TIGR01409; hypothetical protein 559857 1166226 BR0564 Brucella suis 1330 hypothetical protein NP_697580.1 559141 R 204722 CDS NP_697581.1 23501454 1166227 complement(560160..560813) 1 NC_004310.3 identified by similarity to SP:Q51645; match to protein family HMM PF00702; match to protein family HMM TIGR01428; match to protein family HMM TIGR01493; haloacid dehalogenase 560813 1166227 BR0565 Brucella suis 1330 haloacid dehalogenase NP_697581.1 560160 R 204722 CDS NP_697582.1 23501455 1166228 561036..561635 1 NC_004310.3 identified by match to protein family HMM PF00081; match to protein family HMM PF02777; Fe/Mn family superoxide dismutase 561635 1166228 BR0566 Brucella suis 1330 Fe/Mn family superoxide dismutase NP_697582.1 561036 D 204722 CDS NP_697583.1 23501456 1166229 561681..562256 1 NC_004310.3 hypothetical protein 562256 1166229 BR0567 Brucella suis 1330 hypothetical protein NP_697583.1 561681 D 204722 CDS NP_697584.1 23501457 1166230 complement(562260..564368) 1 NC_004310.3 identified by similarity to EGAD:17797; match to protein family HMM PF00326; match to protein family HMM PF02897; oligopeptidase B 564368 ptrB 1166230 ptrB Brucella suis 1330 oligopeptidase B NP_697584.1 562260 R 204722 CDS NP_697585.1 23501458 1166231 564941..565369 1 NC_004310.3 identified by similarity to EGAD:35422; match to protein family HMM PF05443; Ros/MucR family transcriptional regulator 565369 1166231 BR0569 Brucella suis 1330 Ros/MucR family transcriptional regulator NP_697585.1 564941 D 204722 CDS NP_697586.1 23501459 1166232 complement(565577..565825) 1 NC_004310.3 hypothetical protein 565825 1166232 BR0570 Brucella suis 1330 hypothetical protein NP_697586.1 565577 R 204722 CDS NP_697587.1 23501460 1166233 566070..566525 1 NC_004310.3 hypothetical protein 566525 1166233 BR0571 Brucella suis 1330 hypothetical protein NP_697587.1 566070 D 204722 CDS NP_697588.1 23501461 1166234 566672..567316 1 NC_004310.3 identified by similarity to GP:15155912; hypothetical protein 567316 1166234 BR0572 Brucella suis 1330 hypothetical protein NP_697588.1 566672 D 204722 CDS NP_697589.2 161486700 1166235 567428..568651 1 NC_004310.3 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 568651 1166235 BR0573 Brucella suis 1330 amidase NP_697589.2 567428 D 204722 CDS NP_697590.1 23501463 1166236 complement(568692..569117) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6032; match to protein family HMM PF02657; hypothetical protein 569117 1166236 BR0574 Brucella suis 1330 hypothetical protein NP_697590.1 568692 R 204722 CDS NP_697591.1 23501464 1166237 complement(569197..569646) 1 NC_004310.3 identified by similarity to SP:Q52968; hypothetical protein 569646 1166237 BR0575 Brucella suis 1330 hypothetical protein NP_697591.1 569197 R 204722 CDS NP_697592.1 23501465 1166238 complement(569832..569951) 1 NC_004310.3 hypothetical protein 569951 1166238 BR0576 Brucella suis 1330 hypothetical protein NP_697592.1 569832 R 204722 CDS NP_697593.1 23501466 1166239 569937..571766 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 571766 1166239 BR0577 Brucella suis 1330 sensor histidine kinase NP_697593.1 569937 D 204722 CDS NP_697594.1 23501467 1166240 571693..572709 1 NC_004310.3 identified by match to protein family HMM PF01471; peptidoglycan-binding protein 572709 1166240 BR0578 Brucella suis 1330 peptidoglycan-binding protein NP_697594.1 571693 D 204722 CDS NP_697595.1 23501468 1166241 572723..573070 1 NC_004310.3 hypothetical protein 573070 1166241 BR0579 Brucella suis 1330 hypothetical protein NP_697595.1 572723 D 204722 CDS NP_697596.1 23501469 1166242 complement(573081..574157) 1 NC_004310.3 identified by similarity to GP:15073936; hypothetical protein 574157 1166242 BR0580 Brucella suis 1330 hypothetical protein NP_697596.1 573081 R 204722 CDS NP_697597.1 23501470 1166243 complement(574355..574897) 1 NC_004310.3 identified by similarity to GP:15073939; hypothetical protein 574897 1166243 BR0581 Brucella suis 1330 hypothetical protein NP_697597.1 574355 R 204722 CDS NP_697598.1 23501471 1166244 complement(574890..575501) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6040; hypothetical protein 575501 1166244 BR0582 Brucella suis 1330 hypothetical protein NP_697598.1 574890 R 204722 CDS NP_697599.1 23501472 1166245 complement(575508..577664) 1 NC_004310.3 identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein 577664 1166245 BR0583 Brucella suis 1330 1A family penicillin-binding protein NP_697599.1 575508 R 204722 CDS NP_697600.1 23501473 1166246 578085..578534 1 NC_004310.3 hypothetical protein 578534 1166246 BR0584 Brucella suis 1330 hypothetical protein NP_697600.1 578085 D 204722 CDS NP_697601.1 23501474 1166247 578578..579732 1 NC_004310.3 terminase large subunit 579732 1166247 BR0585 Brucella suis 1330 terminase large subunit NP_697601.1 578578 D 204722 CDS NP_697602.1 23501475 1166248 579764..580957 1 NC_004310.3 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; HK97 family portal protein 580957 1166248 BR0586 Brucella suis 1330 HK97 family portal protein NP_697602.1 579764 D 204722 CDS NP_697603.1 23501476 1166249 580954..581331 1 NC_004310.3 identified by similarity to GP:15155959; hypothetical protein 581331 1166249 BR0587 Brucella suis 1330 hypothetical protein NP_697603.1 580954 D 204722 CDS NP_697604.1 23501477 1166250 581318..581986 1 NC_004310.3 identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543; protease 581986 1166250 BR0588 Brucella suis 1330 protease NP_697604.1 581318 D 204722 CDS NP_697605.1 23501478 1166251 582008..583282 1 NC_004310.3 identified by match to protein family HMM TIGR01554; HK97 family major capsid protein 583282 1166251 BR0589 Brucella suis 1330 HK97 family major capsid protein NP_697605.1 582008 D 204722 CDS NP_697606.1 23501479 1166252 583447..584013 1 NC_004310.3 identified by similarity to GP:15155962; hypothetical protein 584013 1166252 BR0590 Brucella suis 1330 hypothetical protein NP_697606.1 583447 D 204722 CDS NP_697607.1 23501480 1166253 584010..584348 1 NC_004310.3 identified by similarity to GP:15155963; match to protein family HMM TIGR01563; hypothetical protein 584348 1166253 BR0591 Brucella suis 1330 hypothetical protein NP_697607.1 584010 D 204722 CDS NP_697608.1 23501481 1166254 584345..584512 1 NC_004310.3 hypothetical protein 584512 1166254 BR0592 Brucella suis 1330 hypothetical protein NP_697608.1 584345 D 204722 CDS NP_697609.1 23501482 1166255 584472..584879 1 NC_004310.3 identified by similarity to GP:15155964; hypothetical protein 584879 1166255 BR0593 Brucella suis 1330 hypothetical protein NP_697609.1 584472 D 204722 CDS NP_697610.1 23501483 1166256 584920..585333 1 NC_004310.3 identified by similarity to OMNI:CC2781; match to protein family HMM TIGR02126; hypothetical protein 585333 1166256 BR0594 Brucella suis 1330 hypothetical protein NP_697610.1 584920 D 204722 CDS NP_697611.1 23501484 1166257 585336..585671 1 NC_004310.3 identified by similarity to GP:15155967; hypothetical protein 585671 1166257 BR0595 Brucella suis 1330 hypothetical protein NP_697611.1 585336 D 204722 CDS NP_697612.1 23501485 1166259 585890..586435 1 NC_004310.3 identified by similarity to GP:15155972; hypothetical protein 586435 1166259 BR0597 Brucella suis 1330 hypothetical protein NP_697612.1 585890 D 204722 CDS NP_697613.1 23501486 1166260 586438..587070 1 NC_004310.3 identified by similarity to GP:15155973; hypothetical protein 587070 1166260 BR0598 Brucella suis 1330 hypothetical protein NP_697613.1 586438 D 204722 CDS NP_697614.1 23501487 1166261 587067..587942 1 NC_004310.3 identified by similarity to GP:15155974; hypothetical protein 587942 1166261 BR0599 Brucella suis 1330 hypothetical protein NP_697614.1 587067 D 204722 CDS NP_697615.1 23501488 1166262 587939..588373 1 NC_004310.3 identified by match to protein family HMM PF00877; NLP/P60 family protein 588373 1166262 BR0600 Brucella suis 1330 NLP/P60 family protein NP_697615.1 587939 D 204722 CDS NP_697616.1 23501489 1166264 592297..592503 1 NC_004310.3 identified by similarity to GP:15155977; hypothetical protein 592503 1166264 BR0602 Brucella suis 1330 hypothetical protein NP_697616.1 592297 D 204722 CDS NP_697617.1 23501490 1166265 592665..592961 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6060; hypothetical protein 592961 1166265 BR0603 Brucella suis 1330 hypothetical protein NP_697617.1 592665 D 204722 CDS NP_697618.1 23501491 1166266 593040..593729 1 NC_004310.3 identified by similarity to OMNI:CC2766; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 593729 1166266 BR0604 Brucella suis 1330 DNA-binding response regulator NP_697618.1 593040 D 204722 CDS NP_697619.1 23501492 1166267 593816..595114 1 NC_004310.3 identified by similarity to GP:14027143; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 595114 1166267 BR0605 Brucella suis 1330 sensor histidine kinase NP_697619.1 593816 D 204722 CDS NP_697620.1 23501493 1166268 595175..595660 1 NC_004310.3 identified by similarity to GP:15073947; outer membrane lipoprotein-like protein 595660 1166268 BR0606 Brucella suis 1330 outer membrane lipoprotein-like protein NP_697620.1 595175 D 204722 CDS NP_697621.1 23501494 1166269 595761..596900 1 NC_004310.3 cytochrome c-type biogenesis protein 596900 1166269 BR0607 Brucella suis 1330 cytochrome c-type biogenesis protein NP_697621.1 595761 D 204722 CDS NP_697622.1 23501495 1166270 596897..597394 1 NC_004310.3 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 597394 ccmE 1166270 ccmE Brucella suis 1330 cytochrome c-type biogenesis protein CcmE NP_697622.1 596897 D 204722 CDS NP_697623.1 23501496 1166271 597414..599405 1 NC_004310.3 identified by similarity to EGAD:8346; match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF 599405 ccmF 1166271 ccmF Brucella suis 1330 cytochrome c-type biogenesis protein CcmF NP_697623.1 597414 D 204722 CDS NP_697624.1 23501497 1166272 599402..599878 1 NC_004310.3 identified by similarity to SP:P45406; match to protein family HMM PF03918; cytochrome c-type biogenesis protein CcmH 599878 ccmh 1166272 ccmh Brucella suis 1330 cytochrome c-type biogenesis protein CcmH NP_697624.1 599402 D 204722 CDS NP_697625.1 23501498 1166273 600020..601561 1 NC_004310.3 identified by similarity to EGAD:21403; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease 601561 1166273 BR0611 Brucella suis 1330 serine protease NP_697625.1 600020 D 204722 CDS NP_697626.1 23501499 1166274 601655..602362 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 602362 1166274 BR0612 Brucella suis 1330 DNA-binding response regulator NP_697626.1 601655 D 204722 CDS NP_697627.1 23501500 1166275 602362..603765 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 603765 1166275 BR0613 Brucella suis 1330 sensor histidine kinase NP_697627.1 602362 D 204722 CDS NP_697628.1 23501501 1166276 603888..606839 1 NC_004310.3 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 606839 glnE 1166276 glnE Brucella suis 1330 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase NP_697628.1 603888 D 204722 CDS NP_697629.1 23501502 1166277 complement(606884..608995) 1 NC_004310.3 identified by similarity to GP:15156909; match to protein family HMM PF01755; match to protein family HMM PF04932; hypothetical protein 608995 1166277 BR0615 Brucella suis 1330 hypothetical protein NP_697629.1 606884 R 204722 CDS NP_697630.1 23501503 1166278 complement(609266..611617) 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 611617 1166278 BR0616 Brucella suis 1330 sensory box histidine kinase NP_697630.1 609266 R 204722 CDS NP_697631.1 23501504 1166279 complement(612008..614659) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6073; match to protein family HMM PF01433; aminopeptidase 614659 pepN 1166279 pepN Brucella suis 1330 aminopeptidase NP_697631.1 612008 R 204722 CDS NP_697632.1 23501505 1166280 614828..615844 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 615844 1166280 BR0618 Brucella suis 1330 hypothetical protein NP_697632.1 614828 D 204722 CDS NP_697633.1 23501506 1166281 complement(615849..617105) 1 NC_004310.3 identified by match to protein family HMM PF00083; major facilitator family transporter 617105 1166281 BR0619 Brucella suis 1330 major facilitator family transporter NP_697633.1 615849 R 204722 CDS NP_697634.1 23501507 1166282 complement(617267..618139) 1 NC_004310.3 identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758; phage SPO1 DNA polymerase-like protein 618139 1166282 BR0620 Brucella suis 1330 phage SPO1 DNA polymerase-like protein NP_697634.1 617267 R 204722 CDS NP_697635.1 23501508 1166283 618528..620219 1 NC_004310.3 identified by similarity to EGAD:4120; match to protein family HMM PF05187; electron transfer flavoprotein-ubiquinone oxidoreductase 620219 1166283 BR0621 Brucella suis 1330 electron transfer flavoprotein-ubiquinone oxidoreductase NP_697635.1 618528 D 204722 CDS NP_697636.1 23501509 1166284 complement(620335..621303) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6082; match to protein family HMM PF03372; AP endonuclease domain-containing protein 621303 1166284 BR0622 Brucella suis 1330 AP endonuclease domain-containing protein NP_697636.1 620335 R 204722 CDS NP_697637.1 23501510 1166285 complement(621464..622966) 1 NC_004310.3 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase 622966 amn 1166285 amn Brucella suis 1330 AMP nucleosidase NP_697637.1 621464 R 204722 CDS NP_697638.1 23501511 1166286 623019..623177 1 NC_004310.3 hypothetical protein 623177 1166286 BR0624 Brucella suis 1330 hypothetical protein NP_697638.1 623019 D 204722 CDS NP_697639.1 23501512 1166287 623159..623455 1 NC_004310.3 hypothetical protein 623455 1166287 BR0625 Brucella suis 1330 hypothetical protein NP_697639.1 623159 D 204722 CDS NP_697640.1 23501513 1166288 623533..624243 1 NC_004310.3 identified by similarity to OMNI:CC2434; match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 624243 1166288 BR0626 Brucella suis 1330 glutathione S-transferase NP_697640.1 623533 D 204722 CDS NP_697641.1 23501514 1166289 complement(624302..624649) 1 NC_004310.3 identified by similarity to GP:15073978; hypothetical protein 624649 1166289 BR0627 Brucella suis 1330 hypothetical protein NP_697641.1 624302 R 204722 CDS NP_697642.1 23501515 1166290 complement(624646..624936) 1 NC_004310.3 hypothetical protein 624936 1166290 BR0628 Brucella suis 1330 hypothetical protein NP_697642.1 624646 R 204722 CDS NP_697643.1 23501516 1166291 625155..625412 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6087; hypothetical protein 625412 1166291 BR0629 Brucella suis 1330 hypothetical protein NP_697643.1 625155 D 204722 CDS NP_697644.1 23501517 1166292 complement(625472..626245) 1 NC_004310.3 identified by similarity to OMNI:VC0940; match to protein family HMM PF02588; hypothetical protein 626245 1166292 BR0630 Brucella suis 1330 hypothetical protein NP_697644.1 625472 R 204722 CDS NP_697645.1 23501518 1166293 626237..626350 1 NC_004310.3 hypothetical protein 626350 1166293 BR0631 Brucella suis 1330 hypothetical protein NP_697645.1 626237 D 204722 CDS NP_697646.1 23501519 1166294 626509..626604 1 NC_004310.3 hypothetical protein 626604 1166294 BR0632 Brucella suis 1330 hypothetical protein NP_697646.1 626509 D 204722 CDS NP_697647.1 23501520 1166295 626898..627548 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2997; hypothetical protein 627548 1166295 BR0633 Brucella suis 1330 hypothetical protein NP_697647.1 626898 D 204722 CDS NP_697648.1 23501521 1166296 complement(627593..627967) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6597; match to protein family HMM PF04241; hypothetical protein 627967 1166296 BR0634 Brucella suis 1330 hypothetical protein NP_697648.1 627593 R 204722 CDS NP_697649.1 23501522 1166297 complement(627985..629118) 1 NC_004310.3 catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; histidinol-phosphate aminotransferase 629118 1166297 BR0635 Brucella suis 1330 histidinol-phosphate aminotransferase NP_697649.1 627985 R 204722 CDS NP_697650.1 23501523 1166298 complement(629481..630407) 1 NC_004310.3 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase site specific recombinase 630407 1166298 BR0636 Brucella suis 1330 phage integrase site specific recombinase NP_697650.1 629481 R 204722 CDS NP_697651.1 23501524 1166299 complement(630681..631784) 1 NC_004310.3 identified by similarity to GP:841493; match to protein family HMM PF02530; porin 631784 omp2a 1166299 omp2a Brucella suis 1330 porin NP_697651.1 630681 R 204722 CDS NP_697652.1 23501525 1166301 complement(632438..632545) 1 NC_004310.3 hypothetical protein 632545 1166301 BR0638 Brucella suis 1330 hypothetical protein NP_697652.1 632438 R 204722 CDS NP_697653.1 23501526 1166302 632585..633712 1 NC_004310.3 identified by similarity to GP:841494; match to protein family HMM PF02530; porin 633712 omp2b 1166302 omp2b Brucella suis 1330 porin NP_697653.1 632585 D 204722 CDS NP_697654.1 23501527 1166303 633856..634497 1 NC_004310.3 hypothetical protein 634497 1166303 BR0640 Brucella suis 1330 hypothetical protein NP_697654.1 633856 D 204722 CDS NP_697655.1 23501528 1166304 complement(634547..634747) 1 NC_004310.3 hypothetical protein 634747 1166304 BR0641 Brucella suis 1330 hypothetical protein NP_697655.1 634547 R 204722 CDS NP_697656.1 23501529 1166305 634797..635471 1 NC_004310.3 identified by similarity to EGAD:126787; hypothetical protein 635471 1166305 BR0642 Brucella suis 1330 hypothetical protein NP_697656.1 634797 D 204722 CDS NP_697657.1 23501530 1166306 complement(635534..637492) 1 NC_004310.3 identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 637492 1166306 BR0643 Brucella suis 1330 transglycosylase SLT domain-containing protein NP_697657.1 635534 R 204722 CDS NP_697658.1 23501531 1166307 637515..637679 1 NC_004310.3 hypothetical protein 637679 1166307 BR0644 Brucella suis 1330 hypothetical protein NP_697658.1 637515 D 204722 CDS NP_697659.1 23501532 1166308 637762..637854 1 NC_004310.3 hypothetical protein 637854 1166308 BR0645 Brucella suis 1330 hypothetical protein NP_697659.1 637762 D 204722 CDS NP_697660.1 23501533 1166309 638067..638948 1 NC_004310.3 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 638948 dapA 1166309 dapA Brucella suis 1330 dihydrodipicolinate synthase NP_697660.1 638067 D 204722 CDS NP_697661.1 23501534 1166310 639039..639515 1 NC_004310.3 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 639515 smpB 1166310 smpB Brucella suis 1330 SsrA-binding protein NP_697661.1 639039 D 204722 CDS NP_697662.1 23501535 1166311 complement(639751..640422) 1 NC_004310.3 identified by match to protein family HMM PF03167; phage SPO1 DNA polymerase-like protein 640422 1166311 BR0648 Brucella suis 1330 phage SPO1 DNA polymerase-like protein NP_697662.1 639751 R 204722 CDS NP_697663.1 23501536 1166312 complement(640453..641028) 1 NC_004310.3 identified by match to protein family HMM PF01936; hypothetical protein 641028 1166312 BR0649 Brucella suis 1330 hypothetical protein NP_697663.1 640453 R 204722 CDS NP_697664.1 23501537 1166313 complement(641228..641383) 1 NC_004310.3 hypothetical protein 641383 1166313 BR0650 Brucella suis 1330 hypothetical protein NP_697664.1 641228 R 204722 CDS NP_697665.1 23501538 1166314 641425..641826 1 NC_004310.3 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 641826 rpoZ 1166314 rpoZ Brucella suis 1330 DNA-directed RNA polymerase subunit omega NP_697665.1 641425 D 204722 CDS NP_697666.1 23501539 1166315 642067..644319 1 NC_004310.3 identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; RelA/SpoT family protein 644319 1166315 BR0652 Brucella suis 1330 RelA/SpoT family protein NP_697666.1 642067 D 204722 CDS NP_697667.1 23501540 1166316 644327..644905 1 NC_004310.3 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 644905 pyrE 1166316 pyrE Brucella suis 1330 orotate phosphoribosyltransferase NP_697667.1 644327 D 204722 CDS NP_697668.1 23501541 1166317 645074..645820 1 NC_004310.3 identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator 645820 1166317 BR0654 Brucella suis 1330 Crp/Fnr family transcriptional regulator NP_697668.1 645074 D 204722 CDS NP_697669.1 23501542 1166318 646201..647535 1 NC_004310.3 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 647535 hemN-1 1166318 hemN-1 Brucella suis 1330 coproporphyrinogen III oxidase NP_697669.1 646201 D 204722 CDS NP_697670.1 23501543 1166319 complement(647719..648930) 1 NC_004310.3 identified by similarity to EGAD:36955; fosmidomycin resistance protein 648930 fsr 1166319 fsr Brucella suis 1330 fosmidomycin resistance protein NP_697670.1 647719 R 204722 CDS NP_697671.1 23501544 1166320 649182..649964 1 NC_004310.3 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; AraC family transcriptional regulator 649964 1166320 BR0657 Brucella suis 1330 AraC family transcriptional regulator NP_697671.1 649182 D 204722 CDS NP_697672.1 23501545 1166321 650017..650589 1 NC_004310.3 identified by similarity to GP:14027200; hypothetical protein 650589 1166321 BR0658 Brucella suis 1330 hypothetical protein NP_697672.1 650017 D 204722 CDS NP_697673.1 23501546 1166322 650586..650990 1 NC_004310.3 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 650990 acpS 1166322 acpS Brucella suis 1330 4'-phosphopantetheinyl transferase NP_697673.1 650586 D 204722 CDS NP_697674.1 23501547 1166323 651101..651883 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6121; match to protein family HMM PF00461; signal peptidase I 651883 1166323 BR0660 Brucella suis 1330 signal peptidase I NP_697674.1 651101 D 204722 CDS NP_697675.1 23501548 1166324 651852..652589 1 NC_004310.3 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 652589 rncS 1166324 rncS Brucella suis 1330 ribonuclease III NP_697675.1 651852 D 204722 CDS NP_697676.1 23501549 1166325 652632..652730 1 NC_004310.3 hypothetical protein 652730 1166325 BR0662 Brucella suis 1330 hypothetical protein NP_697676.1 652632 D 204722 CDS NP_697677.1 23501550 1166326 652734..653669 1 NC_004310.3 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 653669 era 1166326 era Brucella suis 1330 GTP-binding protein Era NP_697677.1 652734 D 204722 CDS NP_697678.1 23501551 1166327 653696..654439 1 NC_004310.3 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 654439 recO 1166327 recO Brucella suis 1330 DNA repair protein RecO NP_697678.1 653696 D 204722 CDS NP_697679.1 23501552 1166328 complement(654417..654926) 1 NC_004310.3 identified by similarity to GP:15074034; hypothetical protein 654926 1166328 BR0665 Brucella suis 1330 hypothetical protein NP_697679.1 654417 R 204722 CDS NP_697680.1 23501553 1166329 complement(654923..655543) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6141; hypothetical protein 655543 1166329 BR0666 Brucella suis 1330 hypothetical protein NP_697680.1 654923 R 204722 CDS NP_697681.1 23501554 1166330 complement(655543..656406) 1 NC_004310.3 identified by match to protein family HMM PF01571; glycine cleavage system protein T 656406 1166330 BR0667 Brucella suis 1330 glycine cleavage system protein T NP_697681.1 655543 R 204722 CDS NP_697682.1 23501555 1166331 656492..657826 1 NC_004310.3 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 657826 pyrC-1 1166331 pyrC-1 Brucella suis 1330 dihydroorotase NP_697682.1 656492 D 204722 CDS NP_697683.1 23501556 1166332 complement(657875..658639) 1 NC_004310.3 identified by similarity to GP:14027225; hypothetical protein 658639 1166332 BR0669 Brucella suis 1330 hypothetical protein NP_697683.1 657875 R 204722 CDS NP_697684.1 23501557 1166333 complement(658688..658954) 1 NC_004310.3 identified by similarity to GP:15074038; hypothetical protein 658954 1166333 BR0670 Brucella suis 1330 hypothetical protein NP_697684.1 658688 R 204722 CDS NP_697685.1 23501558 1166334 complement(659111..659494) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6146; hypothetical protein 659494 1166334 BR0671 Brucella suis 1330 hypothetical protein NP_697685.1 659111 R 204722 CDS NP_697686.1 23501559 1166335 complement(659574..660017) 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 660017 1166335 BR0672 Brucella suis 1330 MutT/nudix family protein NP_697686.1 659574 R 204722 CDS NP_697687.1 23501560 1166336 660103..660882 1 NC_004310.3 identified by similarity to EGAD:107474; match to protein family HMM PF02586; hypothetical protein 660882 1166336 BR0673 Brucella suis 1330 hypothetical protein NP_697687.1 660103 D 204722 CDS NP_697688.1 23501561 1166337 660937..661551 1 NC_004310.3 identified by match to protein family HMM PF01810; amino acid transporter LysE 661551 1166337 BR0674 Brucella suis 1330 amino acid transporter LysE NP_697688.1 660937 D 204722 CDS NP_697689.1 23501562 1166338 complement(661528..661695) 1 NC_004310.3 hypothetical protein 661695 1166338 BR0675 Brucella suis 1330 hypothetical protein NP_697689.1 661528 R 204722 CDS NP_697690.1 23501563 1166339 661821..661943 1 NC_004310.3 hypothetical protein 661943 1166339 BR0676 Brucella suis 1330 hypothetical protein NP_697690.1 661821 D 204722 CDS NP_697691.1 23501564 1166340 662062..663582 1 NC_004310.3 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 663582 cysS 1166340 cysS Brucella suis 1330 cysteinyl-tRNA synthetase NP_697691.1 662062 D 204722 CDS NP_697692.1 23501565 1166341 663601..663735 1 NC_004310.3 hypothetical protein 663735 1166341 BR0678 Brucella suis 1330 hypothetical protein NP_697692.1 663601 D 204722 CDS NP_697693.1 23501566 1166342 663735..665348 1 NC_004310.3 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA; alpha-isopropylmalate/homocitrate synthase transferase 665348 1166342 BR0679 Brucella suis 1330 alpha-isopropylmalate/homocitrate synthase transferase NP_697693.1 663735 D 204722 CDS NP_697694.1 23501567 1166343 665595..666515 1 NC_004310.3 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; rarD protein 666515 rarD 1166343 rarD Brucella suis 1330 rarD protein NP_697694.1 665595 D 204722 CDS NP_697695.1 23501568 1166344 666648..668381 1 NC_004310.3 identified by match to protein family HMM PF01551; M24/M37 family peptidase 668381 1166344 BR0681 Brucella suis 1330 M24/M37 family peptidase NP_697695.1 666648 D 204722 CDS NP_697696.1 23501569 1166345 complement(668449..669279) 1 NC_004310.3 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 669279 ksgA 1166345 ksgA Brucella suis 1330 dimethyladenosine transferase NP_697696.1 668449 R 204722 CDS NP_697697.1 23501570 1166346 complement(669276..670307) 1 NC_004310.3 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase 670307 pdxA 1166346 pdxA Brucella suis 1330 4-hydroxythreonine-4-phosphate dehydrogenase NP_697697.1 669276 R 204722 CDS NP_697698.1 23501571 1166347 complement(670372..671328) 1 NC_004310.3 peptidyl-prolyl cis-trans isomerase 671328 1166347 BR0684 Brucella suis 1330 peptidyl-prolyl cis-trans isomerase NP_697698.1 670372 R 204722 CDS NP_697699.1 23501572 1166348 complement(671639..674017) 1 NC_004310.3 identified by similarity to EGAD:7471; match to protein family HMM PF04453; organic solvent tolerance 674017 1166348 BR0685 Brucella suis 1330 organic solvent tolerance NP_697699.1 671639 R 204722 CDS NP_697700.1 23501573 1166349 complement(674038..675126) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6205; match to protein family HMM PF03739; hypothetical protein 675126 1166349 BR0686 Brucella suis 1330 hypothetical protein NP_697700.1 674038 R 204722 CDS NP_697701.1 23501574 1166350 complement(675123..676331) 1 NC_004310.3 identified by match to protein family HMM PF03739; hypothetical protein 676331 1166350 BR0687 Brucella suis 1330 hypothetical protein NP_697701.1 675123 R 204722 CDS NP_697702.1 23501575 1166351 complement(676504..676722) 1 NC_004310.3 hypothetical protein 676722 1166351 BR0688 Brucella suis 1330 hypothetical protein NP_697702.1 676504 R 204722 CDS NP_697703.1 23501576 1166352 676741..678234 1 NC_004310.3 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 678234 1166352 BR0689 Brucella suis 1330 leucyl aminopeptidase NP_697703.1 676741 D 204722 CDS NP_697704.1 23501577 1166353 678306..678755 1 NC_004310.3 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 678755 1166353 BR0690 Brucella suis 1330 DNA polymerase III subunit chi NP_697704.1 678306 D 204722 CDS NP_697705.1 23501578 1166354 678755..679318 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6220; hypothetical protein 679318 1166354 BR0691 Brucella suis 1330 hypothetical protein NP_697705.1 678755 D 204722 CDS NP_697706.1 23501579 1166355 complement(679395..681278) 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 681278 1166355 BR0692 Brucella suis 1330 ABC transporter ATP-binding protein NP_697706.1 679395 R 204722 CDS NP_697707.1 23501580 1166356 complement(681321..681833) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6242; match to protein family HMM PF05163; hypothetical protein 681833 1166356 BR0693 Brucella suis 1330 hypothetical protein NP_697707.1 681321 R 204722 CDS NP_697708.1 23501581 1166357 682062..682484 1 NC_004310.3 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 682484 ndk 1166357 ndk Brucella suis 1330 nucleoside diphosphate kinase NP_697708.1 682062 D 204722 CDS NP_697709.1 23501582 1166358 complement(682593..683396) 1 NC_004310.3 identified by similarity to GP:14027320; match to protein family HMM PF03724; hypothetical protein 683396 1166358 BR0695 Brucella suis 1330 hypothetical protein NP_697709.1 682593 R 204722 CDS NP_697710.1 23501583 1166359 complement(683632..684123) 1 NC_004310.3 identified by similarity to SP:P30749; match to protein family HMM PF02391; molybdopterin converting factor subunit 2 684123 moaE 1166359 moaE Brucella suis 1330 molybdopterin converting factor subunit 2 NP_697710.1 683632 R 204722 CDS NP_697711.1 23501584 1166360 complement(684125..684382) 1 NC_004310.3 identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682; molybdopterin converting factor subunit 1 684382 moaD 1166360 moaD Brucella suis 1330 molybdopterin converting factor subunit 1 NP_697711.1 684125 R 204722 CDS NP_697712.1 23501585 1166361 complement(684387..684971) 1 NC_004310.3 identified by similarity to SP:P06978; match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 684971 pgsA 1166361 pgsA Brucella suis 1330 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_697712.1 684387 R 204722 CDS NP_697713.2 161486699 1166362 complement(685090..687162) 1 NC_004310.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 687162 uvrC 1166362 uvrC Brucella suis 1330 excinuclease ABC subunit C NP_697713.2 685090 R 204722 CDS NP_697714.1 23501587 1166363 complement(687162..687917) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase 687917 1166363 BR0700 Brucella suis 1330 short chain dehydrogenase NP_697714.1 687162 R 204722 CDS NP_697715.1 23501588 1166364 688319..688960 1 NC_004310.3 identified by similarity to SP:Q45689; match to protein family HMM PF01389; outer-membrane protein Omp25 688960 omp25 1166364 omp25 Brucella suis 1330 outer-membrane protein Omp25 NP_697715.1 688319 D 204722 CDS NP_697716.1 23501589 1166365 complement(689057..689656) 1 NC_004310.3 identified by similarity to OMNI:CC0147; match to protein family HMM PF02798; glutathione S-transferase 689656 1166365 BR0702 Brucella suis 1330 glutathione S-transferase NP_697716.1 689057 R 204722 CDS NP_697717.1 23501590 1166366 complement(689711..690400) 1 NC_004310.3 identified by match to protein family HMM PF00445; ribonuclease T2 family protein 690400 1166366 BR0703 Brucella suis 1330 ribonuclease T2 family protein NP_697717.1 689711 R 204722 CDS NP_697718.1 23501591 1166367 complement(690413..690883) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6225; hypothetical protein 690883 1166367 BR0704 Brucella suis 1330 hypothetical protein NP_697718.1 690413 R 204722 CDS NP_697719.1 23501592 1166368 complement(690966..691838) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6221; match to protein family HMM PF04378; hypothetical protein 691838 1166368 BR0705 Brucella suis 1330 hypothetical protein NP_697719.1 690966 R 204722 CDS NP_697720.1 23501593 1166369 691994..692839 1 NC_004310.3 identified by similarity to GP:15074178; match to protein family HMM PF00892; hypothetical protein 692839 1166369 BR0706 Brucella suis 1330 hypothetical protein NP_697720.1 691994 D 204722 CDS NP_697721.1 23501594 1166370 692917..695043 1 NC_004310.3 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; molybdopterin-binding oxidoreductase 695043 1166370 BR0707 Brucella suis 1330 molybdopterin-binding oxidoreductase NP_697721.1 692917 D 204722 CDS NP_697722.1 23501595 1166371 complement(695270..695794) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2404; hypothetical protein 695794 1166371 BR0708 Brucella suis 1330 hypothetical protein NP_697722.1 695270 R 204722 CDS NP_697723.2 161486698 1166372 complement(695970..696587) 1 NC_004310.3 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 696587 purN 1166372 purN Brucella suis 1330 phosphoribosylglycinamide formyltransferase NP_697723.2 695970 R 204722 CDS NP_697724.1 23501597 1166373 complement(696584..697663) 1 NC_004310.3 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 697663 purM 1166373 purM Brucella suis 1330 phosphoribosylaminoimidazole synthetase NP_697724.1 696584 R 204722 CDS NP_697725.1 23501598 1166374 complement(697705..697884) 1 NC_004310.3 hypothetical protein 697884 1166374 BR0711 Brucella suis 1330 hypothetical protein NP_697725.1 697705 R 204722 CDS NP_697726.1 23501599 1166375 complement(698012..698113) 1 NC_004310.3 hypothetical protein 698113 1166375 BR0712 Brucella suis 1330 hypothetical protein NP_697726.1 698012 R 204722 CDS NP_697727.1 23501600 1166376 698153..699301 1 NC_004310.3 identified by match to protein family HMM PF01594; permease 699301 1166376 BR0713 Brucella suis 1330 permease NP_697727.1 698153 D 204722 CDS NP_697728.1 23501601 1166377 699341..700036 1 NC_004310.3 identified by similarity to GP:14027358; hypothetical protein 700036 1166377 BR0714 Brucella suis 1330 hypothetical protein NP_697728.1 699341 D 204722 CDS NP_697729.1 23501602 1166378 700033..700902 1 NC_004310.3 epimerase 700902 1166378 BR0715 Brucella suis 1330 epimerase NP_697729.1 700033 D 204722 CDS NP_697730.1 23501603 1166379 complement(700899..701684) 1 NC_004310.3 hypothetical protein 701684 1166379 BR0716 Brucella suis 1330 hypothetical protein NP_697730.1 700899 R 204722 CDS NP_697731.1 23501604 1166380 complement(701757..702461) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 702461 1166380 BR0717 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_697731.1 701757 R 204722 CDS NP_697732.1 23501605 1166381 complement(702623..702838) 1 NC_004310.3 hypothetical protein 702838 1166381 BR0718 Brucella suis 1330 hypothetical protein NP_697732.1 702623 R 204722 CDS NP_697733.1 23501606 1166382 702852..703007 1 NC_004310.3 hypothetical protein 703007 1166382 BR0719 Brucella suis 1330 hypothetical protein NP_697733.1 702852 D 204722 CDS NP_697734.1 23501607 1166383 complement(703160..704833) 1 NC_004310.3 identified by similarity to SP:P33231; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease 704833 lldP 1166383 lldP Brucella suis 1330 L-lactate permease NP_697734.1 703160 R 204722 CDS NP_697735.1 23501608 1166385 705367..705672 1 NC_004310.3 identified by similarity to GP:15074650; match to protein family HMM PF04800; oxidoreductase 705672 1166385 BR0721 Brucella suis 1330 oxidoreductase NP_697735.1 705367 D 204722 CDS NP_697736.1 23501609 1166387 706238..706828 1 NC_004310.3 hypothetical protein 706828 1166387 BR0722 Brucella suis 1330 hypothetical protein NP_697736.1 706238 D 204722 CDS NP_697737.1 23501610 1166388 complement(707049..707660) 1 NC_004310.3 identified by match to protein family HMM PF00929; exonuclease 707660 1166388 BR0723 Brucella suis 1330 exonuclease NP_697737.1 707049 R 204722 CDS NP_697738.1 23501611 1166389 complement(707985..708503) 1 NC_004310.3 identified by similarity to EGAD:40466; adenylate kinase 708503 1166389 BR0724 Brucella suis 1330 adenylate kinase NP_697738.1 707985 R 204722 CDS NP_697739.1 23501612 1166390 complement(708527..710062) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 710062 1166390 BR0725 Brucella suis 1330 acetyltransferase NP_697739.1 708527 R 204722 CDS NP_697740.1 23501613 1166391 complement(710037..710831) 1 NC_004310.3 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 710831 1166391 BR0726 Brucella suis 1330 Cro/CI family transcriptional regulator NP_697740.1 710037 R 204722 CDS NP_697741.1 23501614 1166392 complement(710856..711275) 1 NC_004310.3 hypothetical protein 711275 1166392 BR0727 Brucella suis 1330 hypothetical protein NP_697741.1 710856 R 204722 CDS NP_697742.1 23501615 1166393 711655..712551 1 NC_004310.3 hypothetical protein 712551 1166393 BR0728 Brucella suis 1330 hypothetical protein NP_697742.1 711655 D 204722 CDS NP_697743.1 23501616 1166394 712551..714665 1 NC_004310.3 identified by match to protein family HMM PF00665; transposase 714665 1166394 BR0729 Brucella suis 1330 transposase NP_697743.1 712551 D 204722 CDS NP_697744.1 23501617 1166395 714658..715608 1 NC_004310.3 identified by similarity to GP:11071899; transposition protein 715608 1166395 BR0730 Brucella suis 1330 transposition protein NP_697744.1 714658 D 204722 CDS NP_697745.1 23501618 1166396 715605..717182 1 NC_004310.3 hypothetical protein 717182 1166396 BR0731 Brucella suis 1330 hypothetical protein NP_697745.1 715605 D 204722 CDS NP_697746.1 23501619 1166397 complement(717481..717678) 1 NC_004310.3 hypothetical protein 717678 1166397 BR0732 Brucella suis 1330 hypothetical protein NP_697746.1 717481 R 204722 CDS NP_697747.1 23501620 1166398 717919..719226 1 NC_004310.3 hypothetical protein 719226 1166398 BR0733 Brucella suis 1330 hypothetical protein NP_697747.1 717919 D 204722 CDS NP_697748.1 23501621 1166399 719680..721053 1 NC_004310.3 hypothetical protein 721053 1166399 BR0734 Brucella suis 1330 hypothetical protein NP_697748.1 719680 D 204722 CDS NP_697749.1 23501622 1166400 721187..722020 1 NC_004310.3 hypothetical protein 722020 1166400 BR0735 Brucella suis 1330 hypothetical protein NP_697749.1 721187 D 204722 CDS NP_697750.1 23501623 1166401 complement(722404..722916) 1 NC_004310.3 identified by similarity to GP:15162152; hypothetical protein 722916 1166401 BR0736 Brucella suis 1330 hypothetical protein NP_697750.1 722404 R 204722 CDS NP_697751.1 23501624 1166402 complement(723076..723324) 1 NC_004310.3 lipoprotein 723324 1166402 BR0737 Brucella suis 1330 lipoprotein NP_697751.1 723076 R 204722 CDS NP_697752.1 23501625 1166403 complement(723427..723582) 1 NC_004310.3 hypothetical protein 723582 1166403 BR0738 Brucella suis 1330 hypothetical protein NP_697752.1 723427 R 204722 CDS NP_697753.1 23501626 1166404 complement(723569..724738) 1 NC_004310.3 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase 724738 metC 1166404 metC Brucella suis 1330 cystathionine beta-lyase NP_697753.1 723569 R 204722 CDS NP_697754.1 23501627 1166405 724949..725716 1 NC_004310.3 identified by match to protein family HMM PF01569; PAP2 family protein 725716 1166405 BR0740 Brucella suis 1330 PAP2 family protein NP_697754.1 724949 D 204722 CDS NP_697755.1 23501628 1166406 726172..727203 1 NC_004310.3 identified by similarity to EGAD:35379; match to protein family HMM PF00497; match to protein family HMM TIGR01096; amino acid ABC transporter substrate-binding protein 727203 1166406 BR0741 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_697755.1 726172 D 204722 CDS NP_697756.1 23501629 1166407 727237..727464 1 NC_004310.3 hypothetical protein 727464 1166407 BR0742 Brucella suis 1330 hypothetical protein NP_697756.1 727237 D 204722 CDS NP_697757.1 23501630 1166408 727500..728693 1 NC_004310.3 identified by similarity to EGAD:35466; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 728693 1166408 BR0743 Brucella suis 1330 amino acid ABC transporter permease NP_697757.1 727500 D 204722 CDS NP_697758.1 23501631 1166409 728696..729853 1 NC_004310.3 identified by similarity to SP:P45768; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 729853 1166409 BR0744 Brucella suis 1330 amino acid ABC transporter permease NP_697758.1 728696 D 204722 CDS NP_697759.1 23501632 1166410 729934..730683 1 NC_004310.3 identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 730683 1166410 BR0745 Brucella suis 1330 amino acid ABC transporter ATP-binding protein NP_697759.1 729934 D 204722 CDS NP_697760.1 23501633 1166411 complement(730731..731936) 1 NC_004310.3 catalyzes the formation of catechol from salicylate; salicylate hydroxylase 731936 1166411 BR0746 Brucella suis 1330 salicylate hydroxylase NP_697760.1 730731 R 204722 CDS NP_697761.1 23501634 1166412 complement(731966..732220) 1 NC_004310.3 identified by similarity to GP:15074414; hypothetical protein 732220 1166412 BR0747 Brucella suis 1330 hypothetical protein NP_697761.1 731966 R 204722 CDS NP_697762.1 23501635 1166413 732506..734746 1 NC_004310.3 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 734746 ppk 1166413 ppk Brucella suis 1330 polyphosphate kinase NP_697762.1 732506 D 204722 CDS NP_697763.1 23501636 1166414 734743..736281 1 NC_004310.3 identified by match to protein family HMM PF02541; Ppx/GppA phosphatase 736281 1166414 BR0749 Brucella suis 1330 Ppx/GppA phosphatase NP_697763.1 734743 D 204722 CDS NP_697764.1 23501637 1166415 complement(736411..737568) 1 NC_004310.3 identified by similarity to GP:17739552; match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D 737568 rnd 1166415 rnd Brucella suis 1330 ribonuclease D NP_697764.1 736411 R 204722 CDS NP_697765.1 23501638 1166416 737795..739582 1 NC_004310.3 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 739582 aspS 1166416 aspS Brucella suis 1330 aspartyl-tRNA synthetase NP_697765.1 737795 D 204722 CDS NP_697766.1 23501639 1166417 complement(739666..740862) 1 NC_004310.3 identified by similarity to GP:14027664; hypothetical protein 740862 1166417 BR0752 Brucella suis 1330 hypothetical protein NP_697766.1 739666 R 204722 CDS NP_697767.1 23501640 1166418 740917..741156 1 NC_004310.3 hypothetical protein 741156 1166418 BR0753 Brucella suis 1330 hypothetical protein NP_697767.1 740917 D 204722 CDS NP_697768.1 23501641 1166419 741262..743574 1 NC_004310.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 743574 parC 1166419 parC Brucella suis 1330 DNA topoisomerase IV subunit A NP_697768.1 741262 D 204722 CDS NP_697769.1 23501642 1166420 complement(743753..744502) 1 NC_004310.3 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase 744502 1166420 BR0755 Brucella suis 1330 arginyl-tRNA-protein transferase NP_697769.1 743753 R 204722 CDS NP_697770.1 23501643 1166421 complement(744623..745093) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6587; hypothetical protein 745093 1166421 BR0756 Brucella suis 1330 hypothetical protein NP_697770.1 744623 R 204722 CDS NP_697771.1 23501644 1166422 complement(745240..746277) 1 NC_004310.3 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 746277 hemB 1166422 hemB Brucella suis 1330 delta-aminolevulinic acid dehydratase NP_697771.1 745240 R 204722 CDS NP_697772.1 23501645 1166423 746445..747494 1 NC_004310.3 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 747494 1166423 BR0758 Brucella suis 1330 3-hydroxyisobutyryl-CoA hydrolase NP_697772.1 746445 D 204722 CDS NP_697773.1 23501646 1166424 747508..747942 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6608; hypothetical protein 747942 1166424 BR0759 Brucella suis 1330 hypothetical protein NP_697773.1 747508 D 204722 CDS NP_697774.1 23501647 1166425 748173..748772 1 NC_004310.3 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 748772 1166425 BR0760 Brucella suis 1330 MarR family transcriptional regulator NP_697774.1 748173 D 204722 CDS NP_697775.1 23501648 1166426 complement(748859..748999) 1 NC_004310.3 hypothetical protein 748999 1166426 BR0761 Brucella suis 1330 hypothetical protein NP_697775.1 748859 R 204722 CDS NP_697776.1 23501649 1166427 749134..750435 1 NC_004310.3 identified by match to protein family HMM PF01471; match to protein family HMM TIGR01409; peptidoglycan-binding protein 750435 1166427 BR0762 Brucella suis 1330 peptidoglycan-binding protein NP_697776.1 749134 D 204722 CDS NP_697777.1 23501650 1166428 complement(750441..750536) 1 NC_004310.3 hypothetical protein 750536 1166428 BR0763 Brucella suis 1330 hypothetical protein NP_697777.1 750441 R 204722 CDS NP_697778.1 23501651 1166429 750528..750662 1 NC_004310.3 hypothetical protein 750662 1166429 BR0764 Brucella suis 1330 hypothetical protein NP_697778.1 750528 D 204722 CDS NP_697779.1 23501652 1166430 750666..751982 1 NC_004310.3 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 751982 glyA 1166430 glyA Brucella suis 1330 serine hydroxymethyltransferase NP_697779.1 750666 D 204722 CDS NP_697780.1 23501653 1166431 752224..752700 1 NC_004310.3 identified by similarity to GP:14027700; match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 752700 nrdR 1166431 nrdR Brucella suis 1330 transcriptional regulator NrdR NP_697780.1 752224 D 204722 CDS NP_697781.1 23501654 1166432 752702..753823 1 NC_004310.3 identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 753823 ribD 1166432 ribD Brucella suis 1330 riboflavin biosynthesis protein RibD NP_697781.1 752702 D 204722 CDS NP_697782.1 23501655 1166433 753823..754431 1 NC_004310.3 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 754431 ribE 1166433 ribE Brucella suis 1330 riboflavin synthase subunit alpha NP_697782.1 753823 D 204722 CDS NP_697783.1 23501656 1166434 754514..754987 1 NC_004310.3 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 754987 ribH 1166434 ribH Brucella suis 1330 6,7-dimethyl-8-ribityllumazine synthase NP_697783.1 754514 D 204722 CDS NP_697784.1 23501657 1166435 754993..755508 1 NC_004310.3 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 755508 nusB 1166435 nusB Brucella suis 1330 transcription antitermination protein NusB NP_697784.1 754993 D 204722 CDS NP_697785.1 23501658 1166436 755959..758115 1 NC_004310.3 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 758115 hppA 1166436 hppA Brucella suis 1330 membrane-bound proton-translocating pyrophosphatase NP_697785.1 755959 D 204722 CDS NP_697786.1 23501659 1166437 complement(758187..758705) 1 NC_004310.3 identified by similarity to GP:15074151; match to protein family HMM PF04355; hypothetical protein 758705 1166437 BR0772 Brucella suis 1330 hypothetical protein NP_697786.1 758187 R 204722 CDS NP_697787.1 23501660 1166438 758795..759349 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6629; match to protein family HMM PF03981; hypothetical protein 759349 1166438 BR0773 Brucella suis 1330 hypothetical protein NP_697787.1 758795 D 204722 CDS NP_697788.1 23501661 1166439 759469..760026 1 NC_004310.3 identified by similarity to GP:15074153; hypothetical protein 760026 1166439 BR0774 Brucella suis 1330 hypothetical protein NP_697788.1 759469 D 204722 CDS NP_697789.1 23501662 1166440 complement(760074..760169) 1 NC_004310.3 hypothetical protein 760169 1166440 BR0775 Brucella suis 1330 hypothetical protein NP_697789.1 760074 R 204722 CDS NP_697790.1 23501663 1166441 760144..761184 1 NC_004310.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 761184 plsX 1166441 plsX Brucella suis 1330 glycerol-3-phosphate acyltransferase PlsX NP_697790.1 760144 D 204722 CDS NP_697791.1 23501664 1166442 761432..762403 1 NC_004310.3 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 762403 fabH 1166442 fabH Brucella suis 1330 3-oxoacyl-ACP synthase NP_697791.1 761432 D 204722 CDS NP_697792.1 23501665 1166443 762522..762845 1 NC_004310.3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 762845 ihfA 1166443 ihfA Brucella suis 1330 integration host factor subunit alpha NP_697792.1 762522 D 204722 CDS NP_697793.1 23501666 1166444 763379..763921 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6634; hypothetical protein 763921 1166444 BR0779 Brucella suis 1330 hypothetical protein NP_697793.1 763379 D 204722 CDS NP_697794.1 23501667 1166445 complement(763971..764288) 1 NC_004310.3 identified by similarity to SP:P30743; match to protein family HMM PF00893; sugE protein 764288 sugE 1166445 sugE Brucella suis 1330 sugE protein NP_697794.1 763971 R 204722 CDS NP_697795.1 23501668 1166447 complement(764634..766172) 1 NC_004310.3 identified by match to protein family HMM PF02397; sugar transferase 766172 1166447 BR0781 Brucella suis 1330 sugar transferase NP_697795.1 764634 R 204722 CDS NP_697796.1 23501669 1166448 complement(766302..766517) 1 NC_004310.3 identified by similarity to GP:14027725; hypothetical protein 766517 1166448 BR0782 Brucella suis 1330 hypothetical protein NP_697796.1 766302 R 204722 CDS NP_697797.1 23501670 1166449 complement(766526..767113) 1 NC_004310.3 identified by similarity to EGAD:19692; match to protein family HMM PF02563; capsule polysaccharide export protein 767113 1166449 BR0783 Brucella suis 1330 capsule polysaccharide export protein NP_697797.1 766526 R 204722 CDS NP_697798.1 23501671 1166450 767096..767194 1 NC_004310.3 hypothetical protein 767194 1166450 BR0784 Brucella suis 1330 hypothetical protein NP_697798.1 767096 D 204722 CDS NP_697799.1 23501672 1166451 767237..767899 1 NC_004310.3 hypothetical protein 767899 1166451 BR0785 Brucella suis 1330 hypothetical protein NP_697799.1 767237 D 204722 CDS NP_697800.1 23501673 1166452 complement(767967..768185) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6654; hypothetical protein 768185 1166452 BR0786 Brucella suis 1330 hypothetical protein NP_697800.1 767967 R 204722 CDS NP_697801.1 23501674 1166453 768537..769613 1 NC_004310.3 identified by match to protein family HMM PF02628; cytochrome c oxidase assembly protein 769613 1166453 BR0787 Brucella suis 1330 cytochrome c oxidase assembly protein NP_697801.1 768537 D 204722 CDS NP_697802.1 23501675 1166454 complement(769766..770698) 1 NC_004310.3 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase 770698 argC 1166454 argC Brucella suis 1330 N-acetyl-gamma-glutamyl-phosphate reductase NP_697802.1 769766 R 204722 CDS NP_697803.1 23501676 1166455 complement(770788..771738) 1 NC_004310.3 catalyzes the formation of putrescine from agmatine; agmatinase 771738 1166455 BR0789 Brucella suis 1330 agmatinase NP_697803.1 770788 R 204722 CDS NP_697804.1 23501677 1166456 complement(771829..772305) 1 NC_004310.3 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 772305 rpsI 1166456 rpsI Brucella suis 1330 30S ribosomal protein S9 NP_697804.1 771829 R 204722 CDS NP_697805.1 23501678 1166457 complement(772308..772772) 1 NC_004310.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 772772 rplM 1166457 rplM Brucella suis 1330 50S ribosomal protein L13 NP_697805.1 772308 R 204722 CDS NP_697806.1 23501679 1166458 complement(773008..773454) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6663; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 773454 1166458 BR0792 Brucella suis 1330 hypothetical protein NP_697806.1 773008 R 204722 CDS NP_697807.1 23501680 1166459 773688..774971 1 NC_004310.3 catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 774971 1166459 BR0793 Brucella suis 1330 O-acetylhomoserine aminocarboxypropyltransferase NP_697807.1 773688 D 204722 CDS NP_697808.1 23501681 1166460 complement(774834..775496) 1 NC_004310.3 hypothetical protein 775496 1166460 BR0794 Brucella suis 1330 hypothetical protein NP_697808.1 774834 R 204722 CDS NP_697809.1 23501682 1166461 775673..775804 1 NC_004310.3 hypothetical protein 775804 1166461 BR0795 Brucella suis 1330 hypothetical protein NP_697809.1 775673 D 204722 CDS NP_697810.1 23501683 1166462 776058..776567 1 NC_004310.3 hypothetical protein 776567 1166462 BR0796 Brucella suis 1330 hypothetical protein NP_697810.1 776058 D 204722 CDS NP_697811.1 23501684 1166463 776564..776959 1 NC_004310.3 hypothetical protein 776959 1166463 BR0797 Brucella suis 1330 hypothetical protein NP_697811.1 776564 D 204722 CDS NP_697812.1 23501685 1166464 777013..777348 1 NC_004310.3 hypothetical protein 777348 1166464 BR0798 Brucella suis 1330 hypothetical protein NP_697812.1 777013 D 204722 CDS NP_697813.1 23501686 1166465 complement(777405..777806) 1 NC_004310.3 hypothetical protein 777806 1166465 BR0799 Brucella suis 1330 hypothetical protein NP_697813.1 777405 R 204722 CDS NP_697814.1 23501687 1166467 778103..778285 1 NC_004310.3 hypothetical protein 778285 1166467 BR0800 Brucella suis 1330 hypothetical protein NP_697814.1 778103 D 204722 CDS NP_697815.1 23501688 1166469 complement(778669..778872) 1 NC_004310.3 hypothetical protein 778872 1166469 BR0801 Brucella suis 1330 hypothetical protein NP_697815.1 778669 R 204722 CDS NP_697816.1 23501689 1166470 779380..779745 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 779745 nuoA 1166470 nuoA Brucella suis 1330 NADH dehydrogenase subunit A NP_697816.1 779380 D 204722 CDS NP_697817.1 23501690 1166471 779736..780317 1 NC_004310.3 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 780317 nuoB 1166471 nuoB Brucella suis 1330 NADH dehydrogenase subunit B NP_697817.1 779736 D 204722 CDS NP_697818.1 23501691 1166472 780430..781038 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 781038 nuoC 1166472 nuoC Brucella suis 1330 NADH dehydrogenase subunit C NP_697818.1 780430 D 204722 CDS NP_697819.1 23501692 1166473 781056..782246 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 782246 nuoD 1166473 nuoD Brucella suis 1330 NADH dehydrogenase subunit D NP_697819.1 781056 D 204722 CDS NP_697820.1 23501693 1166474 782246..782959 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 782959 nuoE 1166474 nuoE Brucella suis 1330 NADH dehydrogenase subunit E NP_697820.1 782246 D 204722 CDS NP_697821.1 23501694 1166475 782963..784270 1 NC_004310.3 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 784270 nuoF 1166475 nuoF Brucella suis 1330 NADH dehydrogenase I subunit F NP_697821.1 782963 D 204722 CDS NP_697822.1 23501695 1166476 784405..786489 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 786489 nuoG 1166476 nuoG Brucella suis 1330 NADH dehydrogenase subunit G NP_697822.1 784405 D 204722 CDS NP_697823.1 23501696 1166477 786509..787552 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 787552 nuoH 1166477 nuoH Brucella suis 1330 NADH dehydrogenase subunit H NP_697823.1 786509 D 204722 CDS NP_697824.1 23501697 1166478 787565..788056 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 788056 nuoI 1166478 nuoI Brucella suis 1330 NADH dehydrogenase subunit I NP_697824.1 787565 D 204722 CDS NP_697825.1 23501698 1166479 788230..788847 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 788847 nuoJ 1166479 nuoJ Brucella suis 1330 NADH dehydrogenase subunit J NP_697825.1 788230 D 204722 CDS NP_697826.1 23501699 1166480 788858..789166 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 789166 nuoK 1166480 nuoK Brucella suis 1330 NADH dehydrogenase subunit K NP_697826.1 788858 D 204722 CDS NP_697827.1 23501700 1166481 789174..791159 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 791159 nuoL 1166481 nuoL Brucella suis 1330 NADH dehydrogenase subunit L NP_697827.1 789174 D 204722 CDS NP_697828.1 23501701 1166482 791159..792667 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 792667 nuoM 1166482 nuoM Brucella suis 1330 NADH dehydrogenase subunit M NP_697828.1 791159 D 204722 CDS NP_697829.1 23501702 1166483 792689..794125 1 NC_004310.3 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 794125 nuoN 1166483 nuoN Brucella suis 1330 NADH dehydrogenase subunit N NP_697829.1 792689 D 204722 CDS NP_697830.1 23501703 1166484 794151..794948 1 NC_004310.3 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 794948 1166484 BR0816 Brucella suis 1330 biotin--protein ligase NP_697830.1 794151 D 204722 CDS NP_697831.1 23501704 1166485 795142..796818 1 NC_004310.3 identified by match to protein family HMM PF00753; metallo-beta-lactamase 796818 1166485 BR0817 Brucella suis 1330 metallo-beta-lactamase NP_697831.1 795142 D 204722 CDS NP_697832.1 23501705 1166486 796858..797262 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 797262 1166486 BR0818 Brucella suis 1330 glyoxalase NP_697832.1 796858 D 204722 CDS NP_697833.1 23501706 1166487 797265..797534 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1060; hypothetical protein 797534 1166487 BR0819 Brucella suis 1330 hypothetical protein NP_697833.1 797265 D 204722 CDS NP_697834.1 23501707 1166488 797892..798032 1 NC_004310.3 hypothetical protein 798032 1166488 BR0820 Brucella suis 1330 hypothetical protein NP_697834.1 797892 D 204722 CDS NP_697835.1 23501708 1166489 798063..798155 1 NC_004310.3 hypothetical protein 798155 1166489 BR0821 Brucella suis 1330 hypothetical protein NP_697835.1 798063 D 204722 CDS NP_697836.1 23501709 1166490 798382..799710 1 NC_004310.3 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 799710 proS 1166490 proS Brucella suis 1330 prolyl-tRNA synthetase NP_697836.1 798382 D 204722 CDS NP_697837.1 23501710 1166491 799752..801020 1 NC_004310.3 identified by match to protein family HMM PF02687; ABC transporter permease 801020 1166491 BR0823 Brucella suis 1330 ABC transporter permease NP_697837.1 799752 D 204722 CDS NP_697838.1 23501711 1166492 801020..801703 1 NC_004310.3 identified by similarity to SP:P75957; match to protein family HMM PF00005; lipoprotein releasing system ATP-binding protein LolD 801703 lolD 1166492 lolD Brucella suis 1330 lipoprotein releasing system ATP-binding protein LolD NP_697838.1 801020 D 204722 CDS NP_697839.1 23501712 1166493 802362..805853 1 NC_004310.3 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 805853 dnaE 1166493 dnaE Brucella suis 1330 DNA polymerase III subunit alpha NP_697839.1 802362 D 204722 CDS NP_697840.1 23501713 1166494 805894..806091 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0034; hypothetical protein 806091 1166494 BR0826 Brucella suis 1330 hypothetical protein NP_697840.1 805894 D 204722 CDS NP_697841.1 23501714 1166495 complement(806136..806549) 1 NC_004310.3 hypothetical protein 806549 1166495 BR0827 Brucella suis 1330 hypothetical protein NP_697841.1 806136 R 204722 CDS NP_697842.1 23501715 1166496 complement(806821..807792) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1990; hypothetical protein 807792 1166496 BR0828 Brucella suis 1330 hypothetical protein NP_697842.1 806821 R 204722 CDS NP_697843.1 23501716 1166497 807791..807955 1 NC_004310.3 hypothetical protein 807955 1166497 BR0829 Brucella suis 1330 hypothetical protein NP_697843.1 807791 D 204722 CDS NP_697844.1 23501717 1166498 808127..808744 1 NC_004310.3 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 808744 rpsD 1166498 rpsD Brucella suis 1330 30S ribosomal protein S4 NP_697844.1 808127 D 204722 CDS NP_697845.1 23501718 1166499 809253..810134 1 NC_004310.3 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 810134 1166499 BR0831 Brucella suis 1330 C32 tRNA thiolase NP_697845.1 809253 D 204722 CDS NP_697846.1 23501719 1166500 810121..810948 1 NC_004310.3 identified by match to protein family HMM PF00459; inositol monophosphatase 810948 1166500 BR0832 Brucella suis 1330 inositol monophosphatase NP_697846.1 810121 D 204722 CDS NP_697847.1 23501720 1166501 complement(811163..812428) 1 NC_004310.3 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter 812428 1166501 BR0833 Brucella suis 1330 Bcr/CflA subfamily drug resistance transporter NP_697847.1 811163 R 204722 CDS NP_697848.1 23501721 1166502 812412..812612 1 NC_004310.3 hypothetical protein 812612 1166502 BR0834 Brucella suis 1330 hypothetical protein NP_697848.1 812412 D 204722 CDS NP_697849.1 23501722 1166503 complement(812699..813091) 1 NC_004310.3 identified by match to protein family HMM TIGR00365; glutaredoxin-like protein 813091 1166503 BR0835 Brucella suis 1330 glutaredoxin-like protein NP_697849.1 812699 R 204722 CDS NP_697850.1 23501723 1166504 complement(813216..813449) 1 NC_004310.3 identified by match to protein family HMM PF01722; bolA-like protein 813449 1166504 BR0836 Brucella suis 1330 bolA-like protein NP_697850.1 813216 R 204722 CDS NP_697851.1 23501724 1166505 complement(813719..815941) 1 NC_004310.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II 815941 purL 1166505 purL Brucella suis 1330 phosphoribosylformylglycinamidine synthase II NP_697851.1 813719 R 204722 CDS NP_697852.1 23501725 1166506 complement(816128..816529) 1 NC_004310.3 lipoprotein 816529 1166506 BR0838 Brucella suis 1330 lipoprotein NP_697852.1 816128 R 204722 CDS NP_697853.1 23501726 1166507 complement(816589..817236) 1 NC_004310.3 identified by match to protein family HMM PF00043; glutathione S-transferase 817236 1166507 BR0839 Brucella suis 1330 glutathione S-transferase NP_697853.1 816589 R 204722 CDS NP_697854.1 23501727 1166508 complement(817488..818159) 1 NC_004310.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I 818159 purQ 1166508 purQ Brucella suis 1330 phosphoribosylformylglycinamidine synthase I NP_697854.1 817488 R 204722 CDS NP_697855.1 23501728 1166509 complement(818182..818424) 1 NC_004310.3 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS 818424 1166509 BR0841 Brucella suis 1330 phosphoribosylformylglycinamidine synthase subunit PurS NP_697855.1 818182 R 204722 CDS NP_697856.1 23501729 1166510 complement(818540..819304) 1 NC_004310.3 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 819304 purC 1166510 purC Brucella suis 1330 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_697856.1 818540 R 204722 CDS NP_697857.1 23501730 1166511 819560..819883 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0054; hypothetical protein 819883 1166511 BR0843 Brucella suis 1330 hypothetical protein NP_697857.1 819560 D 204722 CDS NP_697858.1 23501731 1166512 819948..820715 1 NC_004310.3 identified by similarity to EGAD:11526; match to protein family HMM PF03328; hydroxyacid aldolase 820715 1166512 BR0844 Brucella suis 1330 hydroxyacid aldolase NP_697858.1 819948 D 204722 CDS NP_697859.1 23501732 1166513 complement(820764..821330) 1 NC_004310.3 identified by similarity to GP:15074696; hypothetical protein 821330 1166513 BR0845 Brucella suis 1330 hypothetical protein NP_697859.1 820764 R 204722 CDS NP_697860.1 23501733 1166514 complement(821340..821441) 1 NC_004310.3 hypothetical protein 821441 1166514 BR0846 Brucella suis 1330 hypothetical protein NP_697860.1 821340 R 204722 CDS NP_697861.1 23501734 1166515 complement(821529..821630) 1 NC_004310.3 hypothetical protein 821630 1166515 BR0847 Brucella suis 1330 hypothetical protein NP_697861.1 821529 R 204722 CDS NP_697862.1 23501735 1166516 821683..822474 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 822474 1166516 BR0848 Brucella suis 1330 glyoxalase NP_697862.1 821683 D 204722 CDS NP_697863.1 23501736 1166517 complement(822700..824001) 1 NC_004310.3 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 824001 purB 1166517 purB Brucella suis 1330 adenylosuccinate lyase NP_697863.1 822700 R 204722 CDS NP_697864.1 23501737 1166518 complement(824028..824705) 1 NC_004310.3 identified by similarity to EGAD:101737; match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase 824705 rpe 1166518 rpe Brucella suis 1330 ribulose-phosphate 3-epimerase NP_697864.1 824028 R 204722 CDS NP_697865.1 23501738 1166519 complement(824863..825789) 1 NC_004310.3 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase 825789 1166519 BR0851 Brucella suis 1330 lipid A biosynthesis lauroyl acyltransferase NP_697865.1 824863 R 204722 CDS NP_697866.1 23501739 1166520 complement(825803..826831) 1 NC_004310.3 identified by match to protein family HMM PF00107; alcohol dehydrogenase 826831 1166520 BR0852 Brucella suis 1330 alcohol dehydrogenase NP_697866.1 825803 R 204722 CDS NP_697867.1 23501740 1166521 complement(826913..828190) 1 NC_004310.3 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-ACP synthase 828190 1166521 BR0853 Brucella suis 1330 3-oxoacyl-ACP synthase NP_697867.1 826913 R 204722 CDS NP_697868.1 23501741 1166522 complement(828192..829373) 1 NC_004310.3 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 829373 1166522 BR0854 Brucella suis 1330 3-oxoacyl-ACP synthase NP_697868.1 828192 R 204722 CDS NP_697869.1 23501742 1166523 complement(829521..829802) 1 NC_004310.3 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein 829802 1166523 BR0855 Brucella suis 1330 acyl carrier protein NP_697869.1 829521 R 204722 CDS NP_697870.1 23501743 1166524 complement(830003..830764) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML6731; match to protein family HMM PF05838; hypothetical protein 830764 1166524 BR0856 Brucella suis 1330 hypothetical protein NP_697870.1 830003 R 204722 CDS NP_697871.1 23501744 1166525 830980..832002 1 NC_004310.3 identified by similarity to EGAD:30590; match to protein family HMM PF01263; aldose 1-epimerase 832002 galM 1166525 galM Brucella suis 1330 aldose 1-epimerase NP_697871.1 830980 D 204722 CDS NP_697872.1 23501745 1166526 complement(831999..832916) 1 NC_004310.3 identified by similarity to SP:P37647; match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase 832916 1166526 BR0858 Brucella suis 1330 2-dehydro-3-deoxygluconokinase NP_697872.1 831999 R 204722 CDS NP_697873.1 23501746 1166527 833117..833848 1 NC_004310.3 identified by similarity to GP:15141057; hypothetical protein 833848 1166527 BR0859 Brucella suis 1330 hypothetical protein NP_697873.1 833117 D 204722 CDS NP_697874.1 23501747 1166528 833852..834991 1 NC_004310.3 identified by match to protein family HMM PF01979; PhnM protein 834991 phnM 1166528 phnM Brucella suis 1330 PhnM protein NP_697874.1 833852 D 204722 CDS NP_697875.1 23501748 1166529 complement(834988..835671) 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 835671 1166529 BR0861 Brucella suis 1330 HAD superfamily hydrolase NP_697875.1 834988 R 204722 CDS NP_697876.1 23501749 1166531 836908..837930 1 NC_004310.3 identified by similarity to OMNI:CC1306; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 837930 1166531 BR0863 Brucella suis 1330 tRNA-dihydrouridine synthase A NP_697876.1 836908 D 204722 CDS NP_697877.1 23501750 1166532 complement(837927..838631) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0447; match to protein family HMM PF00077; hypothetical protein 838631 1166532 BR0864 Brucella suis 1330 hypothetical protein NP_697877.1 837927 R 204722 CDS NP_697878.1 23501751 1166533 complement(838631..838825) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0446; hypothetical protein 838825 1166533 BR0865 Brucella suis 1330 hypothetical protein NP_697878.1 838631 R 204722 CDS NP_697879.1 23501752 1166534 complement(838845..839627) 1 NC_004310.3 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase 839627 cobS 1166534 cobS Brucella suis 1330 cobalamin synthase NP_697879.1 838845 R 204722 CDS NP_697880.1 23501753 1166535 839781..840800 1 NC_004310.3 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 840800 cobT 1166535 cobT Brucella suis 1330 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase NP_697880.1 839781 D 204722 CDS NP_697881.1 23501754 1166536 complement(840908..841387) 1 NC_004310.3 identified by match to protein family HMM PF01037; AsnC family transcriptional regulator 841387 1166536 BR0868 Brucella suis 1330 AsnC family transcriptional regulator NP_697881.1 840908 R 204722 CDS NP_697882.1 23501755 1166537 complement(841516..842157) 1 NC_004310.3 identified by similarity to GP:15074814; hypothetical protein 842157 1166537 BR0869 Brucella suis 1330 hypothetical protein NP_697882.1 841516 R 204722 CDS NP_697883.1 23501756 1166538 complement(842254..842823) 1 NC_004310.3 identified by match to protein family HMM PF00565; nuclease domain-containing protein 842823 1166538 BR0870 Brucella suis 1330 nuclease domain-containing protein NP_697883.1 842254 R 204722 CDS NP_697884.1 23501757 1166539 842794..843072 1 NC_004310.3 hypothetical protein 843072 1166539 BR0871 Brucella suis 1330 hypothetical protein NP_697884.1 842794 D 204722 CDS NP_697885.1 23501758 1166540 843444..844247 1 NC_004310.3 identified by similarity to EGAD:35423; exopolysacchride production negative regulator exoR 844247 1166540 BR0872 Brucella suis 1330 exopolysacchride production negative regulator exoR NP_697885.1 843444 D 204722 CDS NP_697886.1 23501759 1166541 complement(844306..845088) 1 NC_004310.3 identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III 845088 xth-1 1166541 xth-1 Brucella suis 1330 exodeoxyribonuclease III NP_697886.1 844306 R 204722 CDS NP_697887.1 23501760 1166542 845257..845964 1 NC_004310.3 identified by similarity to GP:15075908; match to protein family HMM PF04391; hypothetical protein 845964 1166542 BR0874 Brucella suis 1330 hypothetical protein NP_697887.1 845257 D 204722 CDS NP_697888.1 23501761 1166543 complement(846045..846371) 1 NC_004310.3 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein 846371 1166543 BR0875 Brucella suis 1330 HesB/YadR/YfhF family protein NP_697888.1 846045 R 204722 CDS NP_697889.1 23501762 1166544 846538..847746 1 NC_004310.3 dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 847746 dgt 1166544 dgt Brucella suis 1330 deoxyguanosinetriphosphate triphosphohydrolase-like protein NP_697889.1 846538 D 204722 CDS NP_697890.1 23501763 1166545 847968..849725 1 NC_004310.3 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 849725 argS 1166545 argS Brucella suis 1330 arginyl-tRNA synthetase NP_697890.1 847968 D 204722 CDS NP_697891.1 23501764 1166546 849937..852873 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0862; hypothetical protein 852873 1166546 BR0878 Brucella suis 1330 hypothetical protein NP_697891.1 849937 D 204722 CDS NP_697892.1 23501765 1166547 853074..854087 1 NC_004310.3 identified by match to protein family HMM PF00933; glycosyl hydrolase 854087 1166547 BR0879 Brucella suis 1330 glycosyl hydrolase NP_697892.1 853074 D 204722 CDS NP_697893.1 23501766 1166548 854274..855011 1 NC_004310.3 identified by similarity to GP:14021929; match to protein family HMM PF02616; segregation and condensation protein A 855011 scpA 1166548 scpA Brucella suis 1330 segregation and condensation protein A NP_697893.1 854274 D 204722 CDS NP_697894.1 23501767 1166549 855004..855729 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0859; match to protein family HMM PF04079; match to protein family HMM TIGR00281; segregation and condensation protein B 855729 scpB 1166549 scpB Brucella suis 1330 segregation and condensation protein B NP_697894.1 855004 D 204722 CDS NP_697895.1 23501768 1166550 855851..856093 1 NC_004310.3 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin-arginine translocation protein TatA 856093 tatA 1166550 tatA Brucella suis 1330 twin-arginine translocation protein TatA NP_697895.1 855851 D 204722 CDS NP_697896.1 23501769 1166551 856174..856785 1 NC_004310.3 mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 856785 1166551 BR0883 Brucella suis 1330 sec-independent translocase NP_697896.1 856174 D 204722 CDS NP_697897.1 23501770 1166552 856782..857606 1 NC_004310.3 identified by similarity to EGAD:10132; match to protein family HMM PF00902; match to protein family HMM TIGR00945; Sec-independent protein translocase TatC 857606 tatC 1166552 tatC Brucella suis 1330 Sec-independent protein translocase TatC NP_697897.1 856782 D 204722 CDS NP_697898.1 23501771 1166553 857683..858966 1 NC_004310.3 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 858966 serS 1166553 serS Brucella suis 1330 seryl-tRNA synthetase NP_697898.1 857683 D 204722 CDS NP_697899.1 23501772 1166554 859115..859882 1 NC_004310.3 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 859882 surE 1166554 surE Brucella suis 1330 stationary phase survival protein SurE NP_697899.1 859115 D 204722 CDS NP_697900.1 23501773 1166555 859948..860547 1 NC_004310.3 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 860547 pcm 1166555 pcm Brucella suis 1330 protein-L-isoaspartate O-methyltransferase NP_697900.1 859948 D 204722 CDS NP_697901.1 23501774 1166556 860941..862224 1 NC_004310.3 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; M24/M37 family peptidase 862224 1166556 BR0888 Brucella suis 1330 M24/M37 family peptidase NP_697901.1 860941 D 204722 CDS NP_697902.1 23501775 1166557 complement(862273..863139) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0849; match to protein family HMM PF05673; hypothetical protein 863139 1166557 BR0889 Brucella suis 1330 hypothetical protein NP_697902.1 862273 R 204722 CDS NP_697903.1 23501776 1166558 863299..863640 1 NC_004310.3 identified by similarity to SP:Q9ZG87; match to protein family HMM PF02699; match to protein family HMM TIGR00739; preprotein translocase subunit Yaj subunit 863640 1166558 BR0890 Brucella suis 1330 preprotein translocase subunit Yaj subunit NP_697903.1 863299 D 204722 CDS NP_697904.1 23501777 1166559 863729..866086 1 NC_004310.3 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 866086 1166559 BR0891 Brucella suis 1330 bifunctional preprotein translocase subunit SecD/SecF NP_697904.1 863729 D 204722 CDS NP_697905.1 23501778 1166560 866089..866478 1 NC_004310.3 identified by similarity to GP:14021915; match to protein family HMM PF04635; hypothetical protein 866478 1166560 BR0892 Brucella suis 1330 hypothetical protein NP_697905.1 866089 D 204722 CDS NP_697906.1 23501779 1166561 866484..867317 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0845; hypothetical protein 867317 1166561 BR0893 Brucella suis 1330 hypothetical protein NP_697906.1 866484 D 204722 CDS NP_697907.1 23501780 1166562 complement(867369..868769) 1 NC_004310.3 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 868769 1166562 BR0894 Brucella suis 1330 tRNA (uracil-5-)-methyltransferase Gid NP_697907.1 867369 R 204722 CDS NP_697908.1 23501781 1166563 complement(869029..869175) 1 NC_004310.3 identified by similarity to GP:15074478; hypothetical protein 869175 1166563 BR0895 Brucella suis 1330 hypothetical protein NP_697908.1 869029 R 204722 CDS NP_697909.1 23501782 1166564 869449..870585 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0840; hypothetical protein 870585 1166564 BR0896 Brucella suis 1330 hypothetical protein NP_697909.1 869449 D 204722 CDS NP_697910.1 23501783 1166565 870582..871151 1 NC_004310.3 hypothetical protein 871151 1166565 BR0897 Brucella suis 1330 hypothetical protein NP_697910.1 870582 D 204722 CDS NP_697911.1 23501784 1166567 871531..872988 1 NC_004310.3 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 872988 tig 1166567 tig Brucella suis 1330 trigger factor NP_697911.1 871531 D 204722 CDS NP_697912.1 23501785 1166568 873138..874640 1 NC_004310.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 874640 gatB 1166568 gatB Brucella suis 1330 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_697912.1 873138 D 204722 CDS NP_697913.1 23501786 1166569 874640..875143 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 875143 1166569 BR0900 Brucella suis 1330 acetyltransferase NP_697913.1 874640 D 204722 CDS NP_697914.1 23501787 1166570 complement(875188..875331) 1 NC_004310.3 hypothetical protein 875331 1166570 BR0901 Brucella suis 1330 hypothetical protein NP_697914.1 875188 R 204722 CDS NP_697915.1 23501788 1166571 875303..875713 1 NC_004310.3 Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 875713 1166571 BR0902 Brucella suis 1330 NADH dehydrogenase NP_697915.1 875303 D 204722 CDS NP_697916.1 23501789 1166572 875773..875898 1 NC_004310.3 hypothetical protein 875898 1166572 BR0903 Brucella suis 1330 hypothetical protein NP_697916.1 875773 D 204722 CDS NP_697917.1 23501790 1166573 875907..876377 1 NC_004310.3 identified by similarity to GP:15074249; hypothetical protein 876377 1166573 BR0904 Brucella suis 1330 hypothetical protein NP_697917.1 875907 D 204722 CDS NP_697918.1 23501791 1166574 complement(876421..876954) 1 NC_004310.3 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase 876954 aat 1166574 aat Brucella suis 1330 leucyl/phenylalanyl-tRNA--protein transferase NP_697918.1 876421 R 204722 CDS NP_697919.1 23501792 1166575 complement(877042..878400) 1 NC_004310.3 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 878400 accC 1166575 accC Brucella suis 1330 acetyl-CoA carboxylase biotin carboxylase subunit NP_697919.1 877042 R 204722 CDS NP_697920.1 23501793 1166576 complement(878450..878920) 1 NC_004310.3 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 878920 accB 1166576 accB Brucella suis 1330 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit NP_697920.1 878450 R 204722 CDS NP_697921.1 23501794 1166577 complement(878922..879395) 1 NC_004310.3 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 879395 aroQ 1166577 aroQ Brucella suis 1330 3-dehydroquinate dehydratase NP_697921.1 878922 R 204722 CDS NP_697922.1 23501795 1166578 complement(879639..880436) 1 NC_004310.3 identified by match to protein family HMM PF01323; hypothetical protein 880436 1166578 BR0909 Brucella suis 1330 hypothetical protein NP_697922.1 879639 R 204722 CDS NP_697923.1 23501796 1166579 complement(880484..881899) 1 NC_004310.3 identified by similarity to GP:14021229; match to protein family HMM PF01435; hypothetical protein 881899 1166579 BR0910 Brucella suis 1330 hypothetical protein NP_697923.1 880484 R 204722 CDS NP_697924.1 23501797 1166580 882091..883254 1 NC_004310.3 identified by match to protein family HMM PF00155; class I aminotransferase 883254 1166580 BR0911 Brucella suis 1330 class I aminotransferase NP_697924.1 882091 D 204722 CDS NP_697925.1 23501798 1166581 complement(883373..886141) 1 NC_004310.3 identified by match to protein family HMM TIGR00757; ribonuclease Rne/Rng domain-containing protein 886141 1166581 BR0912 Brucella suis 1330 ribonuclease Rne/Rng domain-containing protein NP_697925.1 883373 R 204722 CDS NP_697926.1 23501799 1166582 886144..886329 1 NC_004310.3 hypothetical protein 886329 1166582 BR0913 Brucella suis 1330 hypothetical protein NP_697926.1 886144 D 204722 CDS NP_697927.1 23501800 1166583 complement(886681..886782) 1 NC_004310.3 hypothetical protein 886782 1166583 BR0914 Brucella suis 1330 hypothetical protein NP_697927.1 886681 R 204722 CDS NP_697928.1 23501801 1166584 886820..888088 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0166; match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 888088 1166584 BR0915 Brucella suis 1330 N-acetylmuramoyl-L-alanine amidase NP_697928.1 886820 D 204722 CDS NP_697929.1 23501802 1166585 888368..890827 1 NC_004310.3 identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1A 890827 1166585 BR0916 Brucella suis 1330 penicillin-binding protein 1A NP_697929.1 888368 D 204722 CDS NP_697930.1 23501803 1166587 complement(892155..892319) 1 NC_004310.3 hypothetical protein 892319 1166587 BR0918 Brucella suis 1330 hypothetical protein NP_697930.1 892155 R 204722 CDS NP_697931.1 23501804 1166588 892312..892623 1 NC_004310.3 identified by similarity to EGAD:46813; IS711, transposase orfA 892623 1166588 BR0919 Brucella suis 1330 IS711, transposase orfA NP_697931.1 892312 D 204722 CDS NP_697932.1 23501805 1166590 complement(893102..893203) 1 NC_004310.3 hypothetical protein 893203 1166590 BR0921 Brucella suis 1330 hypothetical protein NP_697932.1 893102 R 204722 CDS NP_697933.1 23501806 1166591 complement(893200..893466) 1 NC_004310.3 hypothetical protein 893466 1166591 BR0922 Brucella suis 1330 hypothetical protein NP_697933.1 893200 R 204722 CDS NP_697934.1 23501807 1166592 complement(893733..894560) 1 NC_004310.3 identified by similarity to GP:15074676; match to protein family HMM PF04305; hypothetical protein 894560 1166592 BR0923 Brucella suis 1330 hypothetical protein NP_697934.1 893733 R 204722 CDS NP_697935.1 23501808 1166593 complement(894582..895046) 1 NC_004310.3 identified by similarity to EGAD:18740; match to protein family HMM PF00578; bacterioferritin comigratory protein 895046 bcp 1166593 bcp Brucella suis 1330 bacterioferritin comigratory protein NP_697935.1 894582 R 204722 CDS NP_697936.1 23501809 1166594 895291..898731 1 NC_004310.3 identified by similarity to GP:14021072; hypothetical protein 898731 1166594 BR0925 Brucella suis 1330 hypothetical protein NP_697936.1 895291 D 204722 CDS NP_697937.1 23501810 1166595 complement(898790..900043) 1 NC_004310.3 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 900043 tyrS 1166595 tyrS Brucella suis 1330 tyrosyl-tRNA synthetase NP_697937.1 898790 R 204722 CDS NP_697938.1 23501811 1166596 900159..901280 1 NC_004310.3 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 901280 anmK 1166596 anmK Brucella suis 1330 anhydro-N-acetylmuramic acid kinase NP_697938.1 900159 D 204722 CDS NP_697939.1 23501812 1166597 complement(901277..901609) 1 NC_004310.3 identified by similarity to GP:12024949; match to protein family HMM PF00893; quaternary ammonium compound-resistance protein 901609 qacH 1166597 qacH Brucella suis 1330 quaternary ammonium compound-resistance protein NP_697939.1 901277 R 204722 CDS NP_697940.1 23501813 1166598 complement(901721..902395) 1 NC_004310.3 identified by similarity to GP:15074671; hypothetical protein 902395 1166598 BR0929 Brucella suis 1330 hypothetical protein NP_697940.1 901721 R 204722 CDS NP_697941.1 23501814 1166599 902600..903778 1 NC_004310.3 identified by similarity to EGAD:14639; match to protein family HMM PF00266; cysteine desulfurase 903778 1166599 BR0930 Brucella suis 1330 cysteine desulfurase NP_697941.1 902600 D 204722 CDS NP_697942.1 23501815 1166600 903959..905482 1 NC_004310.3 with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 905482 1166600 BR0931 Brucella suis 1330 cysteine desulfurase NP_697942.1 903959 D 204722 CDS NP_697943.1 23501816 1166601 905550..906305 1 NC_004310.3 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; ABC transporter ATP-binding protein 906305 1166601 BR0932 Brucella suis 1330 ABC transporter ATP-binding protein NP_697943.1 905550 D 204722 CDS NP_697944.1 23501817 1166602 906319..907596 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0017; match to protein family HMM PF01458; match to protein family HMM TIGR01981; hypothetical protein 907596 1166602 BR0933 Brucella suis 1330 hypothetical protein NP_697944.1 906319 D 204722 CDS NP_697945.1 23501818 1166603 907678..908922 1 NC_004310.3 identified by match to protein family HMM PF00266; match to protein family HMM TIGR01979; class V aminotransferase 908922 1166603 BR0934 Brucella suis 1330 class V aminotransferase NP_697945.1 907678 D 204722 CDS NP_697946.1 23501819 1166604 908919..909338 1 NC_004310.3 identified by similarity to GP:14021086; match to protein family HMM PF01883; hypothetical protein 909338 1166604 BR0935 Brucella suis 1330 hypothetical protein NP_697946.1 908919 D 204722 CDS NP_697947.1 23501820 1166605 complement(909372..910343) 1 NC_004310.3 identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein 910343 1166605 BR0936 Brucella suis 1330 glycosyl transferase group 2 family protein NP_697947.1 909372 R 204722 CDS NP_697948.1 23501821 1166607 910746..911543 1 NC_004310.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 911543 ppnK 1166607 ppnK Brucella suis 1330 inorganic polyphosphate/ATP-NAD kinase NP_697948.1 910746 D 204722 CDS NP_697949.1 23501822 1166608 911871..913319 1 NC_004310.3 identified by similarity to EGAD:20681; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD-box ATP dependent DNA helicase 913319 1166608 BR0938 Brucella suis 1330 DEAD-box ATP dependent DNA helicase NP_697949.1 911871 D 204722 CDS NP_697950.1 23501823 1166609 complement(913556..913936) 1 NC_004310.3 identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein 913936 1166609 BR0939 Brucella suis 1330 HesB/YadR/YfhF family protein NP_697950.1 913556 R 204722 CDS NP_697951.1 23501824 1166610 914129..914752 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0072; hypothetical protein 914752 1166610 BR0940 Brucella suis 1330 hypothetical protein NP_697951.1 914129 D 204722 CDS NP_697952.1 23501825 1166611 914737..914829 1 NC_004310.3 hypothetical protein 914829 1166611 BR0941 Brucella suis 1330 hypothetical protein NP_697952.1 914737 D 204722 CDS NP_697953.1 23501826 1166612 914833..915033 1 NC_004310.3 identified by match to protein family HMM PF00403; heavy metal-binding domain-containing protein 915033 1166612 BR0942 Brucella suis 1330 heavy metal-binding domain-containing protein NP_697953.1 914833 D 204722 CDS NP_697954.1 23501827 1166613 915077..915322 1 NC_004310.3 hypothetical protein 915322 1166613 BR0943 Brucella suis 1330 hypothetical protein NP_697954.1 915077 D 204722 CDS NP_697955.1 23501828 1166614 915360..916028 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0876; match to protein family HMM PF01135; protein-L-isoaspartate O-methyltransferase 916028 1166614 BR0944 Brucella suis 1330 protein-L-isoaspartate O-methyltransferase NP_697955.1 915360 D 204722 CDS NP_697956.1 23501829 1166615 916167..917537 1 NC_004310.3 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844; outer membrane efflux family protein 917537 1166615 BR0945 Brucella suis 1330 outer membrane efflux family protein NP_697956.1 916167 D 204722 CDS NP_697957.1 23501830 1166616 917787..918518 1 NC_004310.3 identified by similarity to GP:14021943; hypothetical protein 918518 1166616 BR0946 Brucella suis 1330 hypothetical protein NP_697957.1 917787 D 204722 CDS NP_697958.1 23501831 1166617 918613..918816 1 NC_004310.3 hypothetical protein 918816 1166617 BR0947 Brucella suis 1330 hypothetical protein NP_697958.1 918613 D 204722 CDS NP_697959.1 23501832 1166618 918809..921541 1 NC_004310.3 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 921541 valS 1166618 valS Brucella suis 1330 valyl-tRNA synthetase NP_697959.1 918809 D 204722 CDS NP_697960.1 23501833 1166620 complement(923299..924174) 1 NC_004310.3 identified by match to protein family HMM PF03446; oxidoreductase 924174 1166620 BR0950 Brucella suis 1330 oxidoreductase NP_697960.1 923299 R 204722 CDS NP_697961.1 23501834 1166621 complement(924202..924822) 1 NC_004310.3 identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein 924822 1166621 BR0951 Brucella suis 1330 glutathione S-transferase domain-containing protein NP_697961.1 924202 R 204722 CDS NP_697962.1 23501835 1166622 complement(924995..925828) 1 NC_004310.3 identified by similarity to EGAD:6543; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 925828 1166622 BR0952 Brucella suis 1330 amino acid ABC transporter permease NP_697962.1 924995 R 204722 CDS NP_697963.1 23501836 1166623 complement(925831..926553) 1 NC_004310.3 identified by similarity to EGAD:8421; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 926553 1166623 BR0953 Brucella suis 1330 amino acid ABC transporter permease NP_697963.1 925831 R 204722 CDS NP_697964.1 23501837 1166624 complement(926569..926748) 1 NC_004310.3 hypothetical protein 926748 1166624 BR0954 Brucella suis 1330 hypothetical protein NP_697964.1 926569 R 204722 CDS NP_697965.1 23501838 1166625 complement(926796..927602) 1 NC_004310.3 identified by similarity to EGAD:37042; match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 927602 1166625 BR0955 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_697965.1 926796 R 204722 CDS NP_697966.1 23501839 1166626 complement(927947..928450) 1 NC_004310.3 identified by similarity to SP:P32125; match to protein family HMM PF03205; match to protein family HMM TIGR00176; molybdopterin-guanine dinucleotide biosynthesis protein B 928450 mobB 1166626 mobB Brucella suis 1330 molybdopterin-guanine dinucleotide biosynthesis protein B NP_697966.1 927947 R 204722 CDS NP_697967.1 23501840 1166627 complement(928447..929112) 1 NC_004310.3 identified by similarity to SP:P32173; molybdopterin-guanine dinucleotide biosynthesis protein A 929112 mobA 1166627 mobA Brucella suis 1330 molybdopterin-guanine dinucleotide biosynthesis protein A NP_697967.1 928447 R 204722 CDS NP_697968.1 23501841 1166628 complement(929288..930322) 1 NC_004310.3 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A 930322 moaA 1166628 moaA Brucella suis 1330 molybdenum cofactor biosynthesis protein A NP_697968.1 929288 R 204722 CDS NP_697969.1 23501842 1166629 930509..930868 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0426; hypothetical protein 930868 1166629 BR0959 Brucella suis 1330 hypothetical protein NP_697969.1 930509 D 204722 CDS NP_697970.1 23501843 1166630 complement(930936..932042) 1 NC_004310.3 identified by match to protein family HMM PF01360; monooxygenase 932042 1166630 BR0960 Brucella suis 1330 monooxygenase NP_697970.1 930936 R 204722 CDS NP_697971.1 23501844 1166631 complement(932386..934005) 1 NC_004310.3 identified by similarity to SP:P00923; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase, class I 934005 fumB 1166631 fumB Brucella suis 1330 fumarate hydratase, class I NP_697971.1 932386 R 204722 CDS NP_697972.1 23501845 1166632 934521..936239 1 NC_004310.3 identified by similarity to GP:15156702; hypothetical protein 936239 1166632 BR0962 Brucella suis 1330 hypothetical protein NP_697972.1 934521 D 204722 CDS NP_697973.1 23501846 1166634 complement(936734..936859) 1 NC_004310.3 hypothetical protein 936859 1166634 BR0963 Brucella suis 1330 hypothetical protein NP_697973.1 936734 R 204722 CDS NP_697974.1 23501847 1166636 complement(937040..937291) 1 NC_004310.3 identified by similarity to GP:15159178; match to protein family HMM PF04226; hypothetical protein 937291 1166636 BR0964 Brucella suis 1330 hypothetical protein NP_697974.1 937040 R 204722 CDS NP_697975.1 23501848 1166637 937446..937607 1 NC_004310.3 hypothetical protein 937607 1166637 BR0965 Brucella suis 1330 hypothetical protein NP_697975.1 937446 D 204722 CDS NP_697976.1 23501849 1166639 complement(937800..938825) 1 NC_004310.3 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 938825 1166639 BR0966 Brucella suis 1330 phage integrase site specific recombinase NP_697976.1 937800 R 204722 CDS NP_697977.1 23501850 1166640 939000..940202 1 NC_004310.3 hypothetical protein 940202 1166640 BR0967 Brucella suis 1330 hypothetical protein NP_697977.1 939000 D 204722 CDS NP_697978.1 23501851 1166641 940199..940429 1 NC_004310.3 hypothetical protein 940429 1166641 BR0968 Brucella suis 1330 hypothetical protein NP_697978.1 940199 D 204722 CDS NP_697979.1 23501852 1166642 940426..940701 1 NC_004310.3 hypothetical protein 940701 1166642 BR0969 Brucella suis 1330 hypothetical protein NP_697979.1 940426 D 204722 CDS NP_697980.1 23501853 1166643 940724..941311 1 NC_004310.3 hypothetical protein 941311 1166643 BR0970 Brucella suis 1330 hypothetical protein NP_697980.1 940724 D 204722 CDS NP_697981.1 23501854 1166644 941546..942256 1 NC_004310.3 identified by similarity to EGAD:151783; hypothetical protein 942256 1166644 BR0971 Brucella suis 1330 hypothetical protein NP_697981.1 941546 D 204722 CDS NP_697982.1 23501855 1166645 complement(942604..942774) 1 NC_004310.3 identified by similarity to EGAD:176501; hypothetical protein 942774 1166645 BR0972 Brucella suis 1330 hypothetical protein NP_697982.1 942604 R 204722 CDS NP_697983.1 23501856 1166646 942792..942971 1 NC_004310.3 hypothetical protein 942971 1166646 BR0973 Brucella suis 1330 hypothetical protein NP_697983.1 942792 D 204722 CDS NP_697984.1 23501857 1166647 complement(943122..943436) 1 NC_004310.3 identified by similarity to GP:15073548; hypothetical protein 943436 1166647 BR0974 Brucella suis 1330 hypothetical protein NP_697984.1 943122 R 204722 CDS NP_697985.1 23501858 1166648 complement(943436..943756) 1 NC_004310.3 identified by similarity to GP:15073547; hypothetical protein 943756 1166648 BR0975 Brucella suis 1330 hypothetical protein NP_697985.1 943436 R 204722 CDS NP_697986.1 23501859 1166650 944544..944855 1 NC_004310.3 identified by similarity to EGAD:46813; IS711, transposase orfA 944855 1166650 BR0977 Brucella suis 1330 IS711, transposase orfA NP_697986.1 944544 D 204722 CDS NP_697987.1 23501860 1166652 945335..946054 1 NC_004310.3 hypothetical protein 946054 1166652 BR0979 Brucella suis 1330 hypothetical protein NP_697987.1 945335 D 204722 CDS NP_697988.1 23501861 1166653 946189..947835 1 NC_004310.3 hypothetical protein 947835 1166653 BR0980 Brucella suis 1330 hypothetical protein NP_697988.1 946189 D 204722 CDS NP_697989.1 23501862 1166654 948161..949393 1 NC_004310.3 identified by similarity to GP:5616097; glycosyl transferase WboA 949393 1166654 BR0981 Brucella suis 1330 glycosyl transferase WboA NP_697989.1 948161 D 204722 CDS NP_697990.1 23501863 1166655 949390..950949 1 NC_004310.3 identified by similarity to EGAD:103475; match to protein family HMM PF00534; group 1 glycosyl transferase 950949 1166655 BR0982 Brucella suis 1330 group 1 glycosyl transferase NP_697990.1 949390 D 204722 CDS NP_697991.1 23501864 1166656 complement(950930..951151) 1 NC_004310.3 hypothetical protein 951151 1166656 BR0983 Brucella suis 1330 hypothetical protein NP_697991.1 950930 R 204722 CDS NP_697992.1 23501865 1166657 951392..952054 1 NC_004310.3 identified by similarity to OMNI:PG0293; match to protein family HMM PF05838; secretion activator protein 952054 1166657 BR0984 Brucella suis 1330 secretion activator protein NP_697992.1 951392 D 204722 CDS NP_697993.1 23501866 1166658 complement(952018..952287) 1 NC_004310.3 hypothetical protein 952287 1166658 BR0985 Brucella suis 1330 hypothetical protein NP_697993.1 952018 R 204722 CDS NP_697994.1 23501867 1166659 952423..952674 1 NC_004310.3 hypothetical protein 952674 1166659 BR0986 Brucella suis 1330 hypothetical protein NP_697994.1 952423 D 204722 CDS NP_697995.1 23501868 1166660 952776..952877 1 NC_004310.3 hypothetical protein 952877 1166660 BR0987 Brucella suis 1330 hypothetical protein NP_697995.1 952776 D 204722 CDS NP_697996.1 23501869 1166661 952883..953023 1 NC_004310.3 hypothetical protein 953023 1166661 BR0988 Brucella suis 1330 hypothetical protein NP_697996.1 952883 D 204722 CDS NP_697997.1 23501870 1166662 953014..953361 1 NC_004310.3 identified by similarity to EGAD:91898; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 953361 1166662 BR0989 Brucella suis 1330 arsenate reductase NP_697997.1 953014 D 204722 CDS NP_697998.1 23501871 1166663 953732..954997 1 NC_004310.3 identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein 954997 1166663 BR0990 Brucella suis 1330 rare lipoprotein A family protein NP_697998.1 953732 D 204722 CDS NP_697999.1 23501872 1166664 955108..956298 1 NC_004310.3 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 956298 1166664 BR0991 Brucella suis 1330 D-alanyl-D-alanine carboxypeptidase NP_697999.1 955108 D 204722 CDS NP_698000.1 23501873 1166665 956389..957024 1 NC_004310.3 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 957024 tmk 1166665 tmk Brucella suis 1330 thymidylate kinase NP_698000.1 956389 D 204722 CDS NP_698001.1 23501874 1166666 957021..958103 1 NC_004310.3 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 958103 1166666 BR0993 Brucella suis 1330 DNA polymerase III subunit delta' NP_698001.1 957021 D 204722 CDS NP_698002.1 23501875 1166667 958123..958272 1 NC_004310.3 hypothetical protein 958272 1166667 BR0994 Brucella suis 1330 hypothetical protein NP_698002.1 958123 D 204722 CDS NP_698003.1 23501876 1166668 958272..959819 1 NC_004310.3 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 959819 metG 1166668 metG Brucella suis 1330 methionyl-tRNA synthetase NP_698003.1 958272 D 204722 CDS NP_698004.1 23501877 1166669 959828..960619 1 NC_004310.3 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family hydrolase 960619 1166669 BR0996 Brucella suis 1330 TatD family hydrolase NP_698004.1 959828 D 204722 CDS NP_698005.1 23501878 1166670 960622..961440 1 NC_004310.3 identified by similarity to GP:15074532; match to protein family HMM PF00753; hypothetical protein 961440 1166670 BR0997 Brucella suis 1330 hypothetical protein NP_698005.1 960622 D 204722 CDS NP_698006.1 23501879 1166671 complement(961490..963289) 1 NC_004310.3 responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABC transporter 963289 1166671 BR0998 Brucella suis 1330 cyclic beta-1,2-glucan ABC transporter NP_698006.1 961490 R 204722 CDS NP_698007.1 23501880 1166672 963378..963482 1 NC_004310.3 hypothetical protein 963482 1166672 BR0999 Brucella suis 1330 hypothetical protein NP_698007.1 963378 D 204722 CDS YP_089633.1 52430461 1166673 963602..964582 1 NC_004310.3 identified by similarity to EGAD:7861; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase C 964582 rluC 1166673 rluC Brucella suis 1330 ribosomal large subunit pseudouridine synthase C YP_089633.1 963602 D 204722 CDS NP_698008.1 23501881 1166674 964585..965508 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 965508 1166674 BR1001 Brucella suis 1330 hypothetical protein NP_698008.1 964585 D 204722 CDS NP_698009.1 23501882 1166675 965505..966170 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 966170 1166675 BR1002 Brucella suis 1330 HAD superfamily hydrolase NP_698009.1 965505 D 204722 CDS NP_698010.1 23501883 1166676 966212..966994 1 NC_004310.3 identified by similarity to GP:15156553; hypothetical protein 966994 1166676 BR1003 Brucella suis 1330 hypothetical protein NP_698010.1 966212 D 204722 CDS NP_698011.1 23501884 1166677 complement(967120..968529) 1 NC_004310.3 identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase 968529 glnA 1166677 glnA Brucella suis 1330 glutamine synthetase NP_698011.1 967120 R 204722 CDS NP_698012.1 23501885 1166678 complement(968677..969015) 1 NC_004310.3 identified by similarity to EGAD:35417; match to protein family HMM PF00543; nitrogen regulatory protein P-II 969015 glnB 1166678 glnB Brucella suis 1330 nitrogen regulatory protein P-II NP_698012.1 968677 R 204722 CDS NP_698013.1 23501886 1166679 969322..970827 1 NC_004310.3 identified by similarity to OMNI:CC1965; match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 970827 1166679 BR1006 Brucella suis 1330 hypothetical protein NP_698013.1 969322 D 204722 CDS NP_698014.1 23501887 1166680 complement(970858..971130) 1 NC_004310.3 hypothetical protein 971130 1166680 BR1007 Brucella suis 1330 hypothetical protein NP_698014.1 970858 R 204722 CDS NP_698015.1 23501888 1166681 complement(971127..971831) 1 NC_004310.3 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase 971831 cbbZ 1166681 cbbZ Brucella suis 1330 phosphoglycolate phosphatase NP_698015.1 971127 R 204722 CDS NP_698016.1 23501889 1166682 971886..971999 1 NC_004310.3 hypothetical protein 971999 1166682 BR1009 Brucella suis 1330 hypothetical protein NP_698016.1 971886 D 204722 CDS NP_698017.1 23501890 1166683 972178..972876 1 NC_004310.3 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 972876 rpiA 1166683 rpiA Brucella suis 1330 ribose-5-phosphate isomerase A NP_698017.1 972178 D 204722 CDS NP_698018.1 23501891 1166684 972902..973438 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0413; hypothetical protein 973438 1166684 BR1011 Brucella suis 1330 hypothetical protein NP_698018.1 972902 D 204722 CDS NP_698019.1 23501892 1166685 973592..974986 1 NC_004310.3 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 974986 gor 1166685 gor Brucella suis 1330 glutathione reductase NP_698019.1 973592 D 204722 CDS NP_698020.1 23501893 1166686 975195..976583 1 NC_004310.3 identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358; phospho-2-dehydro-3-deoxyheptonate aldolase, class II 976583 dhs 1166686 dhs Brucella suis 1330 phospho-2-dehydro-3-deoxyheptonate aldolase, class II NP_698020.1 975195 D 204722 CDS NP_698021.1 23501894 1166687 976687..977037 1 NC_004310.3 identified by similarity to SP:P00556; match to protein family HMM PF01219; diacylglycerol kinase 977037 dgkA 1166687 dgkA Brucella suis 1330 diacylglycerol kinase NP_698021.1 976687 D 204722 CDS NP_698022.1 23501895 1166688 977129..978781 1 NC_004310.3 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 978781 nadE 1166688 nadE Brucella suis 1330 NAD synthetase NP_698022.1 977129 D 204722 CDS NP_698023.1 23501896 1166689 978793..980166 1 NC_004310.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 980166 gltX 1166689 gltX Brucella suis 1330 glutamyl-tRNA synthetase NP_698023.1 978793 D 204722 CDS NP_698024.1 23501897 1166690 complement(980980..983304) 1 NC_004310.3 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 983304 maeB 1166690 maeB Brucella suis 1330 malic enzyme NP_698024.1 980980 R 204722 CDS NP_698025.1 23501898 1166691 complement(983522..984502) 1 NC_004310.3 identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase 984502 1166691 BR1018 Brucella suis 1330 mandelate racemase NP_698025.1 983522 R 204722 CDS NP_698026.1 23501899 1166692 984563..985738 1 NC_004310.3 identified by match to protein family HMM PF01740; match to protein family HMM PF02405; toulene ABC transporter permease 985738 1166692 BR1019 Brucella suis 1330 toulene ABC transporter permease NP_698026.1 984563 D 204722 CDS NP_698027.1 23501900 1166693 985955..986812 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 986812 1166693 BR1020 Brucella suis 1330 ABC transporter ATP-binding protein NP_698027.1 985955 D 204722 CDS NP_698028.1 23501901 1166694 986816..987811 1 NC_004310.3 identified by match to protein family HMM PF02470; ABC transporter periplasmic substrate-binding protein 987811 1166694 BR1021 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_698028.1 986816 D 204722 CDS NP_698029.1 23501902 1166695 987835..988437 1 NC_004310.3 identified by similarity to GP:15156733; match to protein family HMM PF03886; lipoprotein 988437 1166695 BR1022 Brucella suis 1330 lipoprotein NP_698029.1 987835 D 204722 CDS NP_698030.1 23501903 1166696 complement(988499..988606) 1 NC_004310.3 hypothetical protein 988606 1166696 BR1023 Brucella suis 1330 hypothetical protein NP_698030.1 988499 R 204722 CDS NP_698031.1 23501904 1166697 complement(988677..993350) 1 NC_004310.3 identified by similarity to GP:15074750; match to protein family HMM TIGR01369; match to protein family HMM TIGR01612; hypothetical protein 993350 1166697 BR1024 Brucella suis 1330 hypothetical protein NP_698031.1 988677 R 204722 CDS NP_698032.1 23501905 1166698 993565..993729 1 NC_004310.3 hypothetical protein 993729 1166698 BR1025 Brucella suis 1330 hypothetical protein NP_698032.1 993565 D 204722 CDS NP_698033.1 23501906 1166699 993965..994288 1 NC_004310.3 identified by similarity to EGAD:5699; match to protein family HMM PF00111; (2Fe-2S) ferredoxin 994288 1166699 BR1026 Brucella suis 1330 (2Fe-2S) ferredoxin NP_698033.1 993965 D 204722 CDS NP_698034.1 23501907 1166701 complement(994932..995552) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0625; hypothetical protein 995552 1166701 BR1028 Brucella suis 1330 hypothetical protein NP_698034.1 994932 R 204722 CDS NP_698035.1 23501908 1166702 995710..996549 1 NC_004310.3 identified by similarity to SP:P28822; match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 996549 folP 1166702 folP Brucella suis 1330 dihydropteroate synthase NP_698035.1 995710 D 204722 CDS NP_698036.1 23501909 1166703 996568..996927 1 NC_004310.3 identified by similarity to EGAD:14090; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 996927 folB 1166703 folB Brucella suis 1330 dihydroneopterin aldolase NP_698036.1 996568 D 204722 CDS NP_698037.1 23501910 1166704 996924..997457 1 NC_004310.3 identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 997457 folK 1166704 folK Brucella suis 1330 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_698037.1 996924 D 204722 CDS NP_698038.1 23501911 1166705 complement(997572..998129) 1 NC_004310.3 identified by similarity to GP:14021684; hypothetical protein 998129 1166705 BR1032 Brucella suis 1330 hypothetical protein NP_698038.1 997572 R 204722 CDS NP_698039.1 23501912 1166706 complement(998381..999454) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0615; match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein 999454 1166706 BR1033 Brucella suis 1330 hypothetical protein NP_698039.1 998381 R 204722 CDS NP_698040.1 23501913 1166707 complement(999451..1000911) 1 NC_004310.3 identified by similarity to GP:14021682; match to protein family HMM PF04317; hypothetical protein 1000911 1166707 BR1034 Brucella suis 1330 hypothetical protein NP_698040.1 999451 R 204722 CDS NP_698041.1 23501914 1166708 complement(1001004..1001504) 1 NC_004310.3 identified by similarity to GP:14021681; hypothetical protein 1001504 1166708 BR1035 Brucella suis 1330 hypothetical protein NP_698041.1 1001004 R 204722 CDS NP_698042.1 23501915 1166709 1001901..1002317 1 NC_004310.3 identified by similarity to EGAD:19456; match to protein family HMM PF01258; dnaK suppressor protein 1002317 dksA 1166709 dksA Brucella suis 1330 dnaK suppressor protein NP_698042.1 1001901 D 204722 CDS NP_698043.1 23501916 1166710 1002327..1002422 1 NC_004310.3 hypothetical protein 1002422 1166710 BR1037 Brucella suis 1330 hypothetical protein NP_698043.1 1002327 D 204722 CDS NP_698044.1 23501917 1166711 complement(1002486..1003718) 1 NC_004310.3 hypothetical protein 1003718 1166711 BR1038 Brucella suis 1330 hypothetical protein NP_698044.1 1002486 R 204722 CDS NP_698045.1 23501918 1166712 1003944..1006781 1 NC_004310.3 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase/response regulator 1006781 1166712 BR1039 Brucella suis 1330 sensory box histidine kinase/response regulator NP_698045.1 1003944 D 204722 CDS NP_698046.1 23501919 1166713 1006806..1008014 1 NC_004310.3 identified by similarity to GP:15140178; match to protein family HMM PF03486; hypothetical protein 1008014 1166713 BR1040 Brucella suis 1330 hypothetical protein NP_698046.1 1006806 D 204722 CDS NP_698047.1 23501920 1166714 1008045..1009367 1 NC_004310.3 identified by match to protein family HMM PF00144; hypothetical protein 1009367 1166714 BR1041 Brucella suis 1330 hypothetical protein NP_698047.1 1008045 D 204722 CDS NP_698048.1 23501921 1166716 complement(1010675..1014469) 1 NC_004310.3 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 1014469 1166716 BR1043 Brucella suis 1330 ribonucleotide-diphosphate reductase subunit alpha NP_698048.1 1010675 R 204722 CDS NP_698049.1 23501922 1166717 1014522..1014761 1 NC_004310.3 hypothetical protein 1014761 1166717 BR1044 Brucella suis 1330 hypothetical protein NP_698049.1 1014522 D 204722 CDS NP_698050.1 23501923 1166718 complement(1015171..1015659) 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 1015659 1166718 BR1045 Brucella suis 1330 MutT/nudix family protein NP_698050.1 1015171 R 204722 CDS NP_698051.1 23501924 1166719 complement(1015900..1016397) 1 NC_004310.3 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 1016397 1166719 BR1046 Brucella suis 1330 xanthine-guanine phosphoribosyltransferase NP_698051.1 1015900 R 204722 CDS NP_698052.1 23501925 1166720 complement(1016847..1017692) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0109; match to protein family HMM PF00582; hypothetical protein 1017692 1166720 BR1047 Brucella suis 1330 hypothetical protein NP_698052.1 1016847 R 204722 CDS NP_698053.1 23501926 1166721 complement(1017770..1018528) 1 NC_004310.3 identified by match to protein family HMM PF00994; cinA-like protein 1018528 1166721 BR1048 Brucella suis 1330 cinA-like protein NP_698053.1 1017770 R 204722 CDS NP_698054.1 23501927 1166722 1018689..1019288 1 NC_004310.3 stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1019288 wrbA 1166722 wrbA Brucella suis 1330 TrpR binding protein WrbA NP_698054.1 1018689 D 204722 CDS NP_698055.1 23501928 1166723 complement(1019266..1019415) 1 NC_004310.3 hypothetical protein 1019415 1166723 BR1050 Brucella suis 1330 hypothetical protein NP_698055.1 1019266 R 204722 CDS NP_698056.1 23501929 1166725 1019593..1020819 1 NC_004310.3 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1020819 1166725 BR1051 Brucella suis 1330 threonine dehydratase NP_698056.1 1019593 D 204722 CDS NP_698057.1 23501930 1166726 1020914..1022521 1 NC_004310.3 identified by similarity to GP:14021336; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD-box ATP dependent DNA helicase 1022521 1166726 BR1052 Brucella suis 1330 DEAD-box ATP dependent DNA helicase NP_698057.1 1020914 D 204722 CDS NP_698058.1 23501931 1166727 1022692..1023720 1 NC_004310.3 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1023720 1166727 BR1053 Brucella suis 1330 cysteine synthase A NP_698058.1 1022692 D 204722 CDS NP_698059.1 23501932 1166728 1023723..1024466 1 NC_004310.3 identified by similarity to GP:15156264; hypothetical protein 1024466 1166728 BR1054 Brucella suis 1330 hypothetical protein NP_698059.1 1023723 D 204722 CDS NP_698060.1 23501933 1166729 1024493..1025347 1 NC_004310.3 identified by similarity to GP:15074554; match to protein family HMM PF00581; rhodanese family protein 1025347 1166729 BR1055 Brucella suis 1330 rhodanese family protein NP_698060.1 1024493 D 204722 CDS NP_698061.1 23501934 1166730 1025349..1025870 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1025870 1166730 BR1056 Brucella suis 1330 acetyltransferase NP_698061.1 1025349 D 204722 CDS NP_698062.1 23501935 1166731 complement(1025909..1026703) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3729; match to protein family HMM PF00990; match to protein family HMM TIGR00254; GGDEF domain-containing protein 1026703 1166731 BR1057 Brucella suis 1330 GGDEF domain-containing protein NP_698062.1 1025909 R 204722 CDS NP_698063.1 23501936 1166732 complement(1027268..1028758) 1 NC_004310.3 identified by match to protein family HMM PF02550; acetyl-CoA hydrolase/transferase 1028758 1166732 BR1058 Brucella suis 1330 acetyl-CoA hydrolase/transferase NP_698063.1 1027268 R 204722 CDS NP_698064.1 23501937 1166733 complement(1029023..1030564) 1 NC_004310.3 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter 1030564 1166733 BR1059 Brucella suis 1330 EmrB/QacA family drug resistance transporter NP_698064.1 1029023 R 204722 CDS NP_698065.1 23501938 1166734 complement(1030564..1031664) 1 NC_004310.3 identified by match to protein family HMM PF00529; HlyD family secretion protein 1031664 1166734 BR1060 Brucella suis 1330 HlyD family secretion protein NP_698065.1 1030564 R 204722 CDS NP_698066.1 23501939 1166735 1032058..1033041 1 NC_004310.3 identified by similarity to SP:P42327; match to protein family HMM PF00107; alcohol dehydrogenase 1033041 1166735 BR1061 Brucella suis 1330 alcohol dehydrogenase NP_698066.1 1032058 D 204722 CDS NP_698067.1 23501940 1166736 complement(1033085..1034227) 1 NC_004310.3 identified by similarity to OMNI:NTL01XF00221; match to protein family HMM PF00557; proline dipeptidase 1034227 pepQ 1166736 pepQ Brucella suis 1330 proline dipeptidase NP_698067.1 1033085 R 204722 CDS NP_698068.1 23501941 1166737 complement(1034486..1035316) 1 NC_004310.3 identified by similarity to GP:15157001; match to protein family HMM PF00515; hypothetical protein 1035316 1166737 BR1063 Brucella suis 1330 hypothetical protein NP_698068.1 1034486 R 204722 CDS NP_698069.1 23501942 1166738 complement(1035425..1036390) 1 NC_004310.3 identified by similarity to GP:2708271; match to protein family HMM PF01758; sodium/bile acid symporter family protein 1036390 1166738 BR1064 Brucella suis 1330 sodium/bile acid symporter family protein NP_698069.1 1035425 R 204722 CDS NP_698070.1 23501943 1166739 complement(1036418..1036570) 1 NC_004310.3 hypothetical protein 1036570 1166739 BR1065 Brucella suis 1330 hypothetical protein NP_698070.1 1036418 R 204722 CDS NP_698071.1 23501944 1166740 complement(1036519..1037526) 1 NC_004310.3 identified by similarity to EGAD:45971; match to protein family HMM PF01370; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase 1037526 galE-1 1166740 galE-1 Brucella suis 1330 UDP-glucose 4-epimerase NP_698071.1 1036519 R 204722 CDS NP_698072.1 23501945 1166741 1037671..1038495 1 NC_004310.3 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 1038495 mazG 1166741 mazG Brucella suis 1330 nucleoside triphosphate pyrophosphohydrolase NP_698072.1 1037671 D 204722 CDS NP_698073.1 23501946 1166742 complement(1038504..1039115) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0717; hypothetical protein 1039115 1166742 BR1068 Brucella suis 1330 hypothetical protein NP_698073.1 1038504 R 204722 CDS NP_698074.1 23501947 1166743 complement(1039158..1039742) 1 NC_004310.3 identified by match to protein family HMM PF00881; nitroreductase 1039742 1166743 BR1069 Brucella suis 1330 nitroreductase NP_698074.1 1039158 R 204722 CDS NP_698075.1 23501948 1166744 1039980..1040972 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0719; hypothetical protein 1040972 1166744 BR1070 Brucella suis 1330 hypothetical protein NP_698075.1 1039980 D 204722 CDS NP_698076.1 23501949 1166745 complement(1041027..1043003) 1 NC_004310.3 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1043003 thrS 1166745 thrS Brucella suis 1330 threonyl-tRNA synthetase NP_698076.1 1041027 R 204722 CDS NP_698077.1 23501950 1166746 complement(1043218..1044450) 1 NC_004310.3 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1044450 1166746 BR1072 Brucella suis 1330 D-alanyl-D-alanine carboxypeptidase NP_698077.1 1043218 R 204722 CDS NP_698078.1 23501951 1166747 complement(1044557..1044928) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0724; match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein 1044928 1166747 BR1073 Brucella suis 1330 hypothetical protein NP_698078.1 1044557 R 204722 CDS NP_698079.1 23501952 1166748 complement(1044930..1045370) 1 NC_004310.3 identified by match to protein family HMM PF01592; NifU-like protein 1045370 1166748 BR1074 Brucella suis 1330 NifU-like protein NP_698079.1 1044930 R 204722 CDS NP_698080.1 23501953 1166749 1045634..1046275 1 NC_004310.3 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1046275 folE 1166749 folE Brucella suis 1330 GTP cyclohydrolase I NP_698080.1 1045634 D 204722 CDS NP_698081.2 161486697 1166750 1046298..1046717 1 NC_004310.3 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1046717 hisI 1166750 hisI Brucella suis 1330 phosphoribosyl-AMP cyclohydrolase NP_698081.2 1046298 D 204722 CDS NP_698082.1 23501955 1166751 1046934..1047881 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0729; match to protein family HMM PF01734; hypothetical protein 1047881 1166751 BR1077 Brucella suis 1330 hypothetical protein NP_698082.1 1046934 D 204722 CDS NP_698083.1 23501956 1166753 1048355..1049599 1 NC_004310.3 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1049599 1166753 BR1078 Brucella suis 1330 phage integrase site specific recombinase NP_698083.1 1048355 D 204722 CDS NP_698084.1 23501957 1166754 1049738..1050142 1 NC_004310.3 hypothetical protein 1050142 1166754 BR1079 Brucella suis 1330 hypothetical protein NP_698084.1 1049738 D 204722 CDS NP_698085.1 23501958 1166755 complement(1051059..1051238) 1 NC_004310.3 hypothetical protein 1051238 1166755 BR1080 Brucella suis 1330 hypothetical protein NP_698085.1 1051059 R 204722 CDS NP_698086.1 23501959 1166756 complement(1051826..1053190) 1 NC_004310.3 hypothetical protein 1053190 1166756 BR1081 Brucella suis 1330 hypothetical protein NP_698086.1 1051826 R 204722 CDS NP_698087.1 23501960 1166757 complement(1053748..1054365) 1 NC_004310.3 identified by match to protein family HMM PF00239; resolvase site-specific recombinase 1054365 1166757 BR1082 Brucella suis 1330 resolvase site-specific recombinase NP_698087.1 1053748 R 204722 CDS NP_698088.1 23501961 1166758 complement(1055164..1055568) 1 NC_004310.3 identified by match to protein family HMM PF02498; BRO family protein 1055568 1166758 BR1083 Brucella suis 1330 BRO family protein NP_698088.1 1055164 R 204722 CDS NP_698089.1 23501962 1166760 complement(1056155..1057300) 1 NC_004310.3 identified by match to protein family HMM PF02515; CAIB/BAIF family protein 1057300 1166760 BR1084 Brucella suis 1330 CAIB/BAIF family protein NP_698089.1 1056155 R 204722 CDS NP_698090.1 23501963 1166761 complement(1057379..1058563) 1 NC_004310.3 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; glutaryl-CoA dehydrogenase 1058563 1166761 BR1085 Brucella suis 1330 glutaryl-CoA dehydrogenase NP_698090.1 1057379 R 204722 CDS NP_698091.1 23501964 1166762 1058665..1059597 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1059597 1166762 BR1086 Brucella suis 1330 LysR family transcriptional regulator NP_698091.1 1058665 D 204722 CDS NP_698092.1 23501965 1166763 complement(1059567..1060550) 1 NC_004310.3 identified by match to protein family HMM PF00296; luciferase 1060550 1166763 BR1087 Brucella suis 1330 luciferase NP_698092.1 1059567 R 204722 CDS NP_698093.1 23501966 1166764 complement(1060631..1063720) 1 NC_004310.3 identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein 1063720 1166764 BR1088 Brucella suis 1330 AcrB/AcrD/AcrF multidrug efflux protein NP_698093.1 1060631 R 204722 CDS NP_698094.1 23501967 1166765 complement(1063730..1064878) 1 NC_004310.3 identified by similarity to OMNI:VC0165; match to protein family HMM TIGR01730; hypothetical protein 1064878 1166765 BR1089 Brucella suis 1330 hypothetical protein NP_698094.1 1063730 R 204722 CDS NP_698095.1 23501968 1166766 1065019..1065585 1 NC_004310.3 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1065585 1166766 BR1090 Brucella suis 1330 TetR family transcriptional regulator NP_698095.1 1065019 D 204722 CDS NP_698096.1 23501969 1166767 complement(1065622..1066755) 1 NC_004310.3 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 1066755 tgt 1166767 tgt Brucella suis 1330 queuine tRNA-ribosyltransferase NP_698096.1 1065622 R 204722 CDS NP_698097.1 23501970 1166768 complement(1066752..1067843) 1 NC_004310.3 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1067843 queA 1166768 queA Brucella suis 1330 S-adenosylmethionine:tRNA ribosyltransferase-isomerase NP_698097.1 1066752 R 204722 CDS NP_698098.1 23501971 1166769 complement(1067965..1068471) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0580; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1068471 1166769 BR1093 Brucella suis 1330 cyclophilin type peptidyl-prolyl cis-trans isomerase NP_698098.1 1067965 R 204722 CDS NP_698099.1 23501972 1166770 complement(1068534..1069124) 1 NC_004310.3 identified by similarity to OMNI:CC1584; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase 1069124 1166770 BR1094 Brucella suis 1330 cyclophilin type peptidyl-prolyl cis-trans isomerase NP_698099.1 1068534 R 204722 CDS NP_698100.1 23501973 1166771 complement(1069145..1069639) 1 NC_004310.3 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1069639 coaD 1166771 coaD Brucella suis 1330 phosphopantetheine adenylyltransferase NP_698100.1 1069145 R 204722 CDS NP_698101.1 23501974 1166772 complement(1069855..1070094) 1 NC_004310.3 hypothetical protein 1070094 1166772 BR1096 Brucella suis 1330 hypothetical protein NP_698101.1 1069855 R 204722 CDS NP_698102.1 23501975 1166773 complement(1070150..1072918) 1 NC_004310.3 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1072918 gyrA 1166773 gyrA Brucella suis 1330 DNA gyrase subunit A NP_698102.1 1070150 R 204722 CDS NP_698103.1 23501976 1166774 1073206..1073835 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0590; match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1073835 1166774 BR1098 Brucella suis 1330 hypothetical protein NP_698103.1 1073206 D 204722 CDS NP_698104.1 23501977 1166775 complement(1073926..1074504) 1 NC_004310.3 guanylate kinase 1074504 1166775 BR1099 Brucella suis 1330 guanylate kinase NP_698104.1 1073926 R 204722 CDS NP_698105.1 23501978 1166776 1074691..1075452 1 NC_004310.3 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1075452 1166776 BR1100 Brucella suis 1330 GntR family transcriptional regulator NP_698105.1 1074691 D 204722 CDS NP_698106.1 23501979 1166777 1075803..1075943 1 NC_004310.3 hypothetical protein 1075943 1166777 BR1101 Brucella suis 1330 hypothetical protein NP_698106.1 1075803 D 204722 CDS NP_698107.1 23501980 1166778 complement(1076137..1076643) 1 NC_004310.3 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein family 1076643 1166778 BR1102 Brucella suis 1330 single-stranded DNA-binding protein family NP_698107.1 1076137 R 204722 CDS NP_698108.1 23501981 1166779 1077211..1077411 1 NC_004310.3 hypothetical protein 1077411 1166779 BR1103 Brucella suis 1330 hypothetical protein NP_698108.1 1077211 D 204722 CDS NP_698109.1 23501982 1166780 1077542..1080466 1 NC_004310.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1080466 uvrA 1166780 uvrA Brucella suis 1330 excinuclease ABC subunit A NP_698109.1 1077542 D 204722 CDS NP_698110.1 23501983 1166781 complement(1080652..1080927) 1 NC_004310.3 identified by similarity to EGAD:8582; match to protein family HMM PF00216; DNA-binding protein HU 1080927 1166781 BR1105 Brucella suis 1330 DNA-binding protein HU NP_698110.1 1080652 R 204722 CDS NP_698111.1 23501984 1166782 complement(1081108..1083546) 1 NC_004310.3 identified by similarity to EGAD:18728; match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM TIGR00763; ATP-dependent protease La 1083546 lon 1166782 lon Brucella suis 1330 ATP-dependent protease La NP_698111.1 1081108 R 204722 CDS NP_698112.1 23501985 1166783 1083867..1083986 1 NC_004310.3 hypothetical protein 1083986 1166783 BR1107 Brucella suis 1330 hypothetical protein NP_698112.1 1083867 D 204722 CDS NP_698113.1 23501986 1166784 complement(1083978..1085252) 1 NC_004310.3 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 1085252 clpX 1166784 clpX Brucella suis 1330 ATP-dependent protease ATP-binding subunit ClpX NP_698113.1 1083978 R 204722 CDS NP_698114.1 23501987 1166785 complement(1085634..1086263) 1 NC_004310.3 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 1086263 clpP 1166785 clpP Brucella suis 1330 ATP-dependent Clp protease proteolytic subunit NP_698114.1 1085634 R 204722 CDS NP_698115.1 23501988 1166786 complement(1086368..1087786) 1 NC_004310.3 GTP-binding protein 1087786 1166786 BR1110 Brucella suis 1330 GTP-binding protein NP_698115.1 1086368 R 204722 CDS NP_698116.1 23501989 1166787 complement(1087977..1088213) 1 NC_004310.3 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1088213 hfq 1166787 hfq Brucella suis 1330 RNA-binding protein Hfq NP_698116.1 1087977 R 204722 CDS NP_698117.1 23501990 1166788 complement(1088219..1088458) 1 NC_004310.3 hypothetical protein 1088458 1166788 BR1112 Brucella suis 1330 hypothetical protein NP_698117.1 1088219 R 204722 CDS NP_698118.1 23501991 1166789 complement(1088442..1089272) 1 NC_004310.3 hypothetical protein 1089272 1166789 BR1113 Brucella suis 1330 hypothetical protein NP_698118.1 1088442 R 204722 CDS NP_698119.1 23501992 1166790 complement(1089321..1090697) 1 NC_004310.3 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component 1090697 trkA 1166790 trkA Brucella suis 1330 potassium transporter peripheral membrane component NP_698119.1 1089321 R 204722 CDS NP_698120.1 23501993 1166791 complement(1090722..1092083) 1 NC_004310.3 identified by similarity to EGAD:5624; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; nitrogen regulation protein NtrX 1092083 ntrX 1166791 ntrX Brucella suis 1330 nitrogen regulation protein NtrX NP_698120.1 1090722 R 204722 CDS NP_698121.1 23501994 1166792 complement(1092085..1094409) 1 NC_004310.3 identified by similarity to EGAD:10502; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR00229; nitrogen regulation protein NtrY 1094409 ntrY 1166792 ntrY Brucella suis 1330 nitrogen regulation protein NtrY NP_698121.1 1092085 R 204722 CDS NP_698122.1 23501995 1166793 complement(1094500..1095975) 1 NC_004310.3 identified by similarity to EGAD:19665; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; match to protein family HMM TIGR01818; nitrogen regulation protein NtrC 1095975 ntrC 1166793 ntrC Brucella suis 1330 nitrogen regulation protein NtrC NP_698122.1 1094500 R 204722 CDS NP_698123.1 23501996 1166794 complement(1095972..1097075) 1 NC_004310.3 identified by similarity to EGAD:22187; match to protein family HMM PF00512; match to protein family HMM PF02518; nitrogen regulation protein NtrB 1097075 ntrB 1166794 ntrB Brucella suis 1330 nitrogen regulation protein NtrB NP_698123.1 1095972 R 204722 CDS NP_698124.1 23501997 1166795 complement(1097114..1098115) 1 NC_004310.3 identified by similarity to EGAD:30550; match to protein family HMM PF01207; match to protein family HMM TIGR00737; nitrogen regulation protein Nifr3 1098115 nifR3 1166795 nifR3 Brucella suis 1330 nitrogen regulation protein Nifr3 NP_698124.1 1097114 R 204722 CDS NP_698125.2 161486696 1166796 1098253..1099482 1 NC_004310.3 bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1099482 ispDF 1166796 ispDF Brucella suis 1330 bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_698125.2 1098253 D 204722 CDS NP_698126.1 23501999 1166797 1099479..1099976 1 NC_004310.3 identified by similarity to GP:15074388; match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence/damage-inducible protein CinA 1099976 cinA 1166797 cinA Brucella suis 1330 competence/damage-inducible protein CinA NP_698126.1 1099479 D 204722 CDS NP_698127.1 23502000 1166798 1100053..1100793 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 1100793 1166798 BR1122 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_698127.1 1100053 D 204722 CDS NP_698128.1 23502001 1166799 complement(1100851..1101261) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0302; match to protein family HMM PF03654; hypothetical protein 1101261 1166799 BR1123 Brucella suis 1330 hypothetical protein NP_698128.1 1100851 R 204722 CDS NP_698129.1 23502002 1166800 complement(1101315..1102283) 1 NC_004310.3 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 1102283 lipA 1166800 lipA Brucella suis 1330 lipoyl synthase NP_698129.1 1101315 R 204722 CDS NP_698130.1 23502003 1166801 complement(1102393..1102554) 1 NC_004310.3 hypothetical protein 1102554 1166801 BR1125 Brucella suis 1330 hypothetical protein NP_698130.1 1102393 R 204722 CDS NP_698131.1 23502004 1166802 complement(1102673..1104136) 1 NC_004310.3 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1104136 lpdA-1 1166802 lpdA-1 Brucella suis 1330 dihydrolipoamide dehydrogenase NP_698131.1 1102673 R 204722 CDS NP_698132.1 23502005 1166803 complement(1104219..1105562) 1 NC_004310.3 identified by similarity to SP:Q9R9N3; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR01349; branched-chain alpha-keto acid dehydrogenase subunit E2 1105562 aceF 1166803 aceF Brucella suis 1330 branched-chain alpha-keto acid dehydrogenase subunit E2 NP_698132.1 1104219 R 204722 CDS NP_698133.1 23502006 1166804 complement(1105580..1106965) 1 NC_004310.3 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 1106965 pdhB 1166804 pdhB Brucella suis 1330 pyruvate dehydrogenase subunit beta NP_698133.1 1105580 R 204722 CDS NP_698134.1 23502007 1166805 complement(1106984..1108024) 1 NC_004310.3 identified by similarity to SP:Q9R9N5; match to protein family HMM PF00676; pyruvate dehydrogenase complex, E1 component subunit alpha 1108024 pdhA 1166805 pdhA Brucella suis 1330 pyruvate dehydrogenase complex, E1 component subunit alpha NP_698134.1 1106984 R 204722 CDS NP_698135.1 23502008 1166806 complement(1108163..1108492) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0293; match to protein family HMM PF04977; hypothetical protein 1108492 1166806 BR1130 Brucella suis 1330 hypothetical protein NP_698135.1 1108163 R 204722 CDS NP_698136.1 23502009 1166807 complement(1108764..1109345) 1 NC_004310.3 identified by similarity to OMNI:CC1925; hypothetical protein 1109345 1166807 BR1131 Brucella suis 1330 hypothetical protein NP_698136.1 1108764 R 204722 CDS NP_698137.1 23502010 1166808 complement(1109682..1110959) 1 NC_004310.3 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 1110959 eno 1166808 eno Brucella suis 1330 phosphopyruvate hydratase NP_698137.1 1109682 R 204722 CDS NP_698138.1 23502011 1166809 complement(1111146..1111979) 1 NC_004310.3 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase 1111979 kdsA 1166809 kdsA Brucella suis 1330 2-dehydro-3-deoxyphosphooctonate aldolase NP_698138.1 1111146 R 204722 CDS NP_698139.1 23502012 1166810 complement(1112085..1113713) 1 NC_004310.3 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 1113713 pyrG 1166810 pyrG Brucella suis 1330 CTP synthetase NP_698139.1 1112085 R 204722 CDS NP_698140.1 23502013 1166811 complement(1113726..1113848) 1 NC_004310.3 hypothetical protein 1113848 1166811 BR1135 Brucella suis 1330 hypothetical protein NP_698140.1 1113726 R 204722 CDS NP_698141.1 23502014 1166812 complement(1113983..1114696) 1 NC_004310.3 identified by similarity to GP:15157507; match to protein family HMM PF03734; hypothetical protein 1114696 1166812 BR1136 Brucella suis 1330 hypothetical protein NP_698141.1 1113983 R 204722 CDS NP_698142.1 23502015 1166813 complement(1114929..1115375) 1 NC_004310.3 identified by match to protein family HMM PF03840; preprotein translocase subunit SecG 1115375 secG 1166813 secG Brucella suis 1330 preprotein translocase subunit SecG NP_698142.1 1114929 R 204722 CDS NP_698143.1 23502016 1166814 complement(1115475..1116239) 1 NC_004310.3 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 1116239 tpiA 1166814 tpiA Brucella suis 1330 triosephosphate isomerase NP_698143.1 1115475 R 204722 CDS NP_698144.1 23502017 1166815 1116458..1118344 1 NC_004310.3 rotamase 1118344 1166815 BR1139 Brucella suis 1330 rotamase NP_698144.1 1116458 D 204722 CDS NP_698145.1 23502018 1166816 1118359..1119378 1 NC_004310.3 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1119378 trpD 1166816 trpD Brucella suis 1330 anthranilate phosphoribosyltransferase NP_698145.1 1118359 D 204722 CDS NP_698146.1 23502019 1166817 1119395..1120201 1 NC_004310.3 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1120201 trpC 1166817 trpC Brucella suis 1330 indole-3-glycerol phosphate synthase NP_698146.1 1119395 D 204722 CDS NP_698147.1 23502020 1166818 1120198..1120695 1 NC_004310.3 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1120695 moaC 1166818 moaC Brucella suis 1330 molybdenum cofactor biosynthesis protein MoaC NP_698147.1 1120198 D 204722 CDS NP_698148.1 23502021 1166819 1120791..1122005 1 NC_004310.3 identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein MoeA 1122005 moeA 1166819 moeA Brucella suis 1330 molybdopterin biosynthesis protein MoeA NP_698148.1 1120791 D 204722 CDS NP_698149.1 23502022 1166820 1122253..1122975 1 NC_004310.3 Represses a number of genes involved in the response to DNA damage; LexA repressor 1122975 lexA 1166820 lexA Brucella suis 1330 LexA repressor NP_698149.1 1122253 D 204722 CDS NP_698150.1 23502023 1166821 complement(1122969..1125500) 1 NC_004310.3 identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; ComEC/Rec2 family protein 1125500 1166821 BR1145 Brucella suis 1330 ComEC/Rec2 family protein NP_698150.1 1122969 R 204722 CDS NP_698151.1 23502024 1166822 complement(1125532..1125708) 1 NC_004310.3 hypothetical protein 1125708 1166822 BR1146 Brucella suis 1330 hypothetical protein NP_698151.1 1125532 R 204722 CDS NP_698152.1 23502025 1166823 1125721..1127142 1 NC_004310.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1127142 gltX 1166823 gltX Brucella suis 1330 glutamyl-tRNA synthetase NP_698152.1 1125721 D 204722 CDS NP_698153.1 23502026 1166824 1127371..1128663 1 NC_004310.3 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1128663 gltA 1166824 gltA Brucella suis 1330 type II citrate synthase NP_698153.1 1127371 D 204722 CDS NP_698154.1 23502027 1166825 complement(1128836..1130023) 1 NC_004310.3 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase 1130023 lpxB 1166825 lpxB Brucella suis 1330 lipid-A-disaccharide synthase NP_698154.1 1128836 R 204722 CDS NP_698155.1 23502028 1166826 complement(1130020..1130922) 1 NC_004310.3 identified by similarity to GP:15074439; hypothetical protein 1130922 1166826 BR1150 Brucella suis 1330 hypothetical protein NP_698155.1 1130020 R 204722 CDS NP_698156.1 23502029 1166827 complement(1130903..1131739) 1 NC_004310.3 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase 1131739 lpxA 1166827 lpxA Brucella suis 1330 UDP-N-acetylglucosamine acyltransferase NP_698156.1 1130903 R 204722 CDS NP_698157.1 23502030 1166828 complement(1131748..1132221) 1 NC_004310.3 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 1132221 fabZ 1166828 fabZ Brucella suis 1330 (3R)-hydroxymyristoyl-ACP dehydratase NP_698157.1 1131748 R 204722 CDS NP_698158.1 23502031 1166829 complement(1132214..1133269) 1 NC_004310.3 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase 1133269 lpxD 1166829 lpxD Brucella suis 1330 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase NP_698158.1 1132214 R 204722 CDS NP_698159.1 23502032 1166830 complement(1133323..1135668) 1 NC_004310.3 identified by match to protein family HMM PF01103; surface antigen 1135668 1166830 BR1154 Brucella suis 1330 surface antigen NP_698159.1 1133323 R 204722 CDS NP_698160.1 23502033 1166831 complement(1135652..1135771) 1 NC_004310.3 hypothetical protein 1135771 1166831 BR1155 Brucella suis 1330 hypothetical protein NP_698160.1 1135652 R 204722 CDS NP_698161.1 23502034 1166832 complement(1136004..1137143) 1 NC_004310.3 identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054; zinc metalloprotease 1137143 1166832 BR1156 Brucella suis 1330 zinc metalloprotease NP_698161.1 1136004 R 204722 CDS NP_698162.1 23502035 1166833 complement(1137210..1138022) 1 NC_004310.3 identified by similarity to EGAD:108469; match to protein family HMM PF01148; phosphatidate cytidylyltransferase 1138022 cdsA 1166833 cdsA Brucella suis 1330 phosphatidate cytidylyltransferase NP_698162.1 1137210 R 204722 CDS NP_698163.1 23502036 1166834 complement(1138127..1138891) 1 NC_004310.3 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1138891 uppS 1166834 uppS Brucella suis 1330 undecaprenyl pyrophosphate synthase NP_698163.1 1138127 R 204722 CDS NP_698164.1 23502037 1166835 complement(1138936..1139496) 1 NC_004310.3 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 1139496 frr 1166835 frr Brucella suis 1330 ribosome recycling factor NP_698164.1 1138936 R 204722 CDS NP_698165.2 161486695 1166836 complement(1139532..1140254) 1 NC_004310.3 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1140254 pyrH 1166836 pyrH Brucella suis 1330 uridylate kinase NP_698165.2 1139532 R 204722 CDS NP_698166.1 23502039 1166837 complement(1140421..1141338) 1 NC_004310.3 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1141338 tsf 1166837 tsf Brucella suis 1330 elongation factor Ts NP_698166.1 1140421 R 204722 CDS NP_698167.1 23502040 1166838 complement(1141528..1142298) 1 NC_004310.3 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1142298 rpsB 1166838 rpsB Brucella suis 1330 30S ribosomal protein S2 NP_698167.1 1141528 R 204722 CDS NP_698168.1 23502041 1166839 complement(1142521..1143015) 1 NC_004310.3 identified by similarity to GP:9107039; hypothetical protein 1143015 1166839 BR1163 Brucella suis 1330 hypothetical protein NP_698168.1 1142521 R 204722 CDS NP_698169.1 23502042 1166840 complement(1143128..1143970) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0524; hypothetical protein 1143970 1166840 BR1164 Brucella suis 1330 hypothetical protein NP_698169.1 1143128 R 204722 CDS NP_698170.1 23502043 1166841 1144114..1144578 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0525; match to protein family HMM PF01042; hypothetical protein 1144578 1166841 BR1165 Brucella suis 1330 hypothetical protein NP_698170.1 1144114 D 204722 CDS NP_698171.1 23502044 1166842 1144580..1145320 1 NC_004310.3 identified by similarity to EGAD:9938; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 1145320 1166842 BR1166 Brucella suis 1330 glycerophosphoryl diester phosphodiesterase NP_698171.1 1144580 D 204722 CDS NP_698172.1 23502045 1166843 1145375..1146562 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0527; match to protein family HMM PF04339; hypothetical protein 1146562 1166843 BR1167 Brucella suis 1330 hypothetical protein NP_698172.1 1145375 D 204722 CDS NP_698173.1 23502046 1166844 1146634..1147056 1 NC_004310.3 identified by match to protein family HMM PF01230; HIT family protein 1147056 1166844 BR1168 Brucella suis 1330 HIT family protein NP_698173.1 1146634 D 204722 CDS NP_698174.1 23502047 1166845 complement(1147163..1149637) 1 NC_004310.3 identified by similarity to EGAD:17776; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01967; ATP-dependent Clp protease ATP-binding subunit ClpA 1149637 clpA 1166845 clpA Brucella suis 1330 ATP-dependent Clp protease ATP-binding subunit ClpA NP_698174.1 1147163 R 204722 CDS NP_698175.1 23502048 1166846 complement(1149644..1150054) 1 NC_004310.3 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS 1150054 clpS 1166846 clpS Brucella suis 1330 ATP-dependent Clp protease adaptor protein ClpS NP_698175.1 1149644 R 204722 CDS NP_698176.1 23502049 1166847 1150055..1150246 1 NC_004310.3 hypothetical protein 1150246 1166847 BR1171 Brucella suis 1330 hypothetical protein NP_698176.1 1150055 D 204722 CDS NP_698177.1 23502050 1166848 1150480..1151898 1 NC_004310.3 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1151898 1166848 BR1172 Brucella suis 1330 D-alanyl-D-alanine carboxypeptidase NP_698177.1 1150480 D 204722 CDS NP_698178.1 23502051 1166849 1151930..1152271 1 NC_004310.3 identified by similarity to GP:15074343; hypothetical protein 1152271 1166849 BR1173 Brucella suis 1330 hypothetical protein NP_698178.1 1151930 D 204722 CDS NP_698179.1 23502052 1166850 complement(1152385..1152822) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0534; hypothetical protein 1152822 1166850 BR1174 Brucella suis 1330 hypothetical protein NP_698179.1 1152385 R 204722 CDS NP_698180.1 23502053 1166851 complement(1152911..1154314) 1 NC_004310.3 identified by similarity to SP:P42630; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase 1154314 sda 1166851 sda Brucella suis 1330 L-serine dehydratase NP_698180.1 1152911 R 204722 CDS NP_698181.1 23502054 1166852 complement(1154512..1154637) 1 NC_004310.3 hypothetical protein 1154637 1166852 BR1176 Brucella suis 1330 hypothetical protein NP_698181.1 1154512 R 204722 CDS NP_698182.1 23502055 1166853 complement(1154836..1155642) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0537; match to protein family HMM PF02698; hypothetical protein 1155642 1166853 BR1177 Brucella suis 1330 hypothetical protein NP_698182.1 1154836 R 204722 CDS NP_698183.1 23502056 1166854 1155805..1156791 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1038; hypothetical protein 1156791 1166854 BR1178 Brucella suis 1330 hypothetical protein NP_698183.1 1155805 D 204722 CDS NP_698184.1 23502057 1166855 complement(1156802..1157188) 1 NC_004310.3 identified by match to protein family HMM PF00376; transcriptional regulator 1157188 1166855 BR1179 Brucella suis 1330 transcriptional regulator NP_698184.1 1156802 R 204722 CDS NP_698185.1 23502058 1166856 1157426..1157686 1 NC_004310.3 hypothetical protein 1157686 1166856 BR1180 Brucella suis 1330 hypothetical protein NP_698185.1 1157426 D 204722 CDS NP_698186.1 23502059 1166857 1157807..1158154 1 NC_004310.3 identified by similarity to GP:15141218; hypothetical protein 1158154 1166857 BR1181 Brucella suis 1330 hypothetical protein NP_698186.1 1157807 D 204722 CDS NP_698187.1 23502060 1166858 1158225..1158539 1 NC_004310.3 identified by similarity to GP:15156035; hypothetical protein 1158539 1166858 BR1182 Brucella suis 1330 hypothetical protein NP_698187.1 1158225 D 204722 CDS NP_698188.1 23502061 1166859 1158984..1159451 1 NC_004310.3 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1159451 1166859 BR1183 Brucella suis 1330 7-cyano-7-deazaguanine reductase NP_698188.1 1158984 D 204722 CDS NP_698189.1 23502062 1166860 complement(1159455..1159604) 1 NC_004310.3 hypothetical protein 1159604 1166860 BR1184 Brucella suis 1330 hypothetical protein NP_698189.1 1159455 R 204722 CDS NP_698190.1 23502063 1166861 1159582..1159758 1 NC_004310.3 hypothetical protein 1159758 1166861 BR1185 Brucella suis 1330 hypothetical protein NP_698190.1 1159582 D 204722 CDS NP_698191.1 23502064 1166862 1159790..1160332 1 NC_004310.3 identified by similarity to OMNI:CC2122; hypothetical protein 1160332 1166862 BR1186 Brucella suis 1330 hypothetical protein NP_698191.1 1159790 D 204722 CDS NP_698192.1 23502065 1166863 complement(1160335..1161747) 1 NC_004310.3 identified by similarity to GP:15159740; match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1161747 1166863 BR1187 Brucella suis 1330 Cro/CI family transcriptional regulator NP_698192.1 1160335 R 204722 CDS NP_698193.1 23502066 1166865 1162752..1164755 1 NC_004310.3 identified by similarity to EGAD:2033; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; propionyl-CoA carboxylase subunit alpha 1164755 pccA 1166865 pccA Brucella suis 1330 propionyl-CoA carboxylase subunit alpha NP_698193.1 1162752 D 204722 CDS NP_698194.1 23502067 1166866 1164816..1166954 1 NC_004310.3 MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1166954 bhbA 1166866 bhbA Brucella suis 1330 methylmalonyl-CoA mutase NP_698194.1 1164816 D 204722 CDS NP_698195.1 23502068 1166867 complement(1167061..1167492) 1 NC_004310.3 identified by similarity to GP:15140764; hypothetical protein 1167492 1166867 BR1191 Brucella suis 1330 hypothetical protein NP_698195.1 1167061 R 204722 CDS NP_698196.1 23502069 1166868 complement(1167610..1169658) 1 NC_004310.3 identified by similarity to OMNI:NTL01BH2941; match to protein family HMM TIGR02123; hypothetical protein 1169658 1166868 BR1192 Brucella suis 1330 hypothetical protein NP_698196.1 1167610 R 204722 CDS NP_698197.1 23502070 1166869 complement(1169699..1169851) 1 NC_004310.3 hypothetical protein 1169851 1166869 BR1193 Brucella suis 1330 hypothetical protein NP_698197.1 1169699 R 204722 CDS NP_698198.1 23502071 1166870 complement(1169895..1170884) 1 NC_004310.3 identified by similarity to EGAD:7185; match to protein family HMM TIGR02122; TRAP transporter solute receptor TAXI family protein 1170884 1166870 BR1194 Brucella suis 1330 TRAP transporter solute receptor TAXI family protein NP_698198.1 1169895 R 204722 CDS NP_698199.1 23502072 1166871 complement(1171030..1171863) 1 NC_004310.3 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 1171863 murI 1166871 murI Brucella suis 1330 glutamate racemase NP_698199.1 1171030 R 204722 CDS NP_698200.1 23502073 1166872 complement(1171860..1172690) 1 NC_004310.3 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methyltransferase 1172690 1166872 BR1196 Brucella suis 1330 RNA methyltransferase NP_698200.1 1171860 R 204722 CDS NP_698201.1 23502074 1166873 1172870..1173454 1 NC_004310.3 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; ThiJ/PfpI family protein 1173454 1166873 BR1197 Brucella suis 1330 ThiJ/PfpI family protein NP_698201.1 1172870 D 204722 CDS NP_698202.1 23502075 1166874 1173543..1173953 1 NC_004310.3 identified by similarity to OMNI:NTL03PA04336; hypothetical protein 1173953 1166874 BR1198 Brucella suis 1330 hypothetical protein NP_698202.1 1173543 D 204722 CDS NP_698203.1 23502076 1166875 1174081..1175295 1 NC_004310.3 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1175295 1166875 BR1199 Brucella suis 1330 isocitrate dehydrogenase NP_698203.1 1174081 D 204722 CDS NP_698204.1 23502077 1166876 1175517..1176962 1 NC_004310.3 identified by similarity to SP:P00634; match to protein family HMM PF00245; alkaline phosphatase 1176962 phoA 1166876 phoA Brucella suis 1330 alkaline phosphatase NP_698204.1 1175517 D 204722 CDS NP_698205.1 23502078 1166877 complement(1177114..1179771) 1 NC_004310.3 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 1179771 alaS 1166877 alaS Brucella suis 1330 alanyl-tRNA synthetase NP_698205.1 1177114 R 204722 CDS NP_698206.1 23502079 1166878 complement(1180164..1181249) 1 NC_004310.3 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 1181249 recA 1166878 recA Brucella suis 1330 recombinase A NP_698206.1 1180164 R 204722 CDS NP_698207.1 23502080 1166879 complement(1181419..1181544) 1 NC_004310.3 hypothetical protein 1181544 1166879 BR1203 Brucella suis 1330 hypothetical protein NP_698207.1 1181419 R 204722 CDS NP_698208.1 23502081 1166880 complement(1181580..1182242) 1 NC_004310.3 identified by match to protein family HMM PF00691; OmpA family protein 1182242 1166880 BR1204 Brucella suis 1330 OmpA family protein NP_698208.1 1181580 R 204722 CDS NP_698209.1 23502082 1166881 complement(1182329..1182913) 1 NC_004310.3 identified by similarity to GP:15075335; lipoprotein 1182913 1166881 BR1205 Brucella suis 1330 lipoprotein NP_698209.1 1182329 R 204722 CDS NP_698210.1 23502083 1166882 complement(1183037..1184350) 1 NC_004310.3 identified by match to protein family HMM PF00004; recombination factor protein RarA 1184350 1166882 BR1206 Brucella suis 1330 recombination factor protein RarA NP_698210.1 1183037 R 204722 CDS NP_698211.1 23502084 1166883 complement(1184497..1185921) 1 NC_004310.3 identified by similarity to EGAD:18959; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease 1185921 1166883 BR1207 Brucella suis 1330 serine protease NP_698211.1 1184497 R 204722 CDS NP_698212.1 23502085 1166884 complement(1186201..1186629) 1 NC_004310.3 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 1186629 rplQ 1166884 rplQ Brucella suis 1330 50S ribosomal protein L17 NP_698212.1 1186201 R 204722 CDS NP_698213.1 23502086 1166885 complement(1186791..1187804) 1 NC_004310.3 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 1187804 rpoA 1166885 rpoA Brucella suis 1330 DNA-directed RNA polymerase subunit alpha NP_698213.1 1186791 R 204722 CDS NP_698214.1 23502087 1166886 complement(1187920..1188309) 1 NC_004310.3 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 1188309 rpsK 1166886 rpsK Brucella suis 1330 30S ribosomal protein S11 NP_698214.1 1187920 R 204722 CDS NP_698215.1 23502088 1166887 complement(1188437..1188805) 1 NC_004310.3 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 1188805 rpsM 1166887 rpsM Brucella suis 1330 30S ribosomal protein S13 NP_698215.1 1188437 R 204722 CDS NP_698216.1 23502089 1166888 complement(1189115..1189699) 1 NC_004310.3 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 1189699 adk 1166888 adk Brucella suis 1330 adenylate kinase NP_698216.1 1189115 R 204722 CDS NP_698217.1 23502090 1166889 complement(1189696..1191036) 1 NC_004310.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 1191036 secY 1166889 secY Brucella suis 1330 preprotein translocase subunit SecY NP_698217.1 1189696 R 204722 CDS NP_698218.1 23502091 1166890 complement(1191197..1191667) 1 NC_004310.3 late assembly protein; 50S ribosomal protein L15 1191667 rplO 1166890 rplO Brucella suis 1330 50S ribosomal protein L15 NP_698218.1 1191197 R 204722 CDS NP_698219.1 23502092 1166891 complement(1191688..1191885) 1 NC_004310.3 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 1191885 rpmD 1166891 rpmD Brucella suis 1330 50S ribosomal protein L30 NP_698219.1 1191688 R 204722 CDS NP_698220.1 23502093 1166892 complement(1192003..1192563) 1 NC_004310.3 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 1192563 rpsE 1166892 rpsE Brucella suis 1330 30S ribosomal protein S5 NP_698220.1 1192003 R 204722 CDS NP_698221.1 23502094 1166893 complement(1192605..1192967) 1 NC_004310.3 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 1192967 rplR 1166893 rplR Brucella suis 1330 50S ribosomal protein L18 NP_698221.1 1192605 R 204722 CDS NP_698222.1 23502095 1166894 complement(1192980..1193513) 1 NC_004310.3 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 1193513 rplF 1166894 rplF Brucella suis 1330 50S ribosomal protein L6 NP_698222.1 1192980 R 204722 CDS NP_698223.1 23502096 1166895 complement(1193552..1193950) 1 NC_004310.3 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 1193950 rpsH 1166895 rpsH Brucella suis 1330 30S ribosomal protein S8 NP_698223.1 1193552 R 204722 CDS NP_698224.1 23502097 1166896 complement(1193961..1194266) 1 NC_004310.3 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 1194266 rpsN 1166896 rpsN Brucella suis 1330 30S ribosomal protein S14 NP_698224.1 1193961 R 204722 CDS NP_698225.1 23502098 1166897 complement(1194294..1194851) 1 NC_004310.3 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 1194851 rplE 1166897 rplE Brucella suis 1330 50S ribosomal protein L5 NP_698225.1 1194294 R 204722 CDS NP_698226.1 23502099 1166898 complement(1194844..1195155) 1 NC_004310.3 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 1195155 rplX 1166898 rplX Brucella suis 1330 50S ribosomal protein L24 NP_698226.1 1194844 R 204722 CDS NP_698227.1 23502100 1166899 complement(1195168..1195536) 1 NC_004310.3 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 1195536 rplN 1166899 rplN Brucella suis 1330 50S ribosomal protein L14 NP_698227.1 1195168 R 204722 CDS NP_698228.1 23502101 1166900 complement(1195605..1195847) 1 NC_004310.3 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 1195847 rpsQ 1166900 rpsQ Brucella suis 1330 30S ribosomal protein S17 NP_698228.1 1195605 R 204722 CDS NP_698229.1 23502102 1166901 complement(1195860..1196060) 1 NC_004310.3 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 1196060 rpmC 1166901 rpmC Brucella suis 1330 50S ribosomal protein L29 NP_698229.1 1195860 R 204722 CDS NP_698230.1 23502103 1166902 complement(1196073..1196486) 1 NC_004310.3 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 1196486 rplP 1166902 rplP Brucella suis 1330 50S ribosomal protein L16 NP_698230.1 1196073 R 204722 CDS NP_698231.1 23502104 1166903 complement(1196525..1197235) 1 NC_004310.3 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 1197235 rpsC 1166903 rpsC Brucella suis 1330 30S ribosomal protein S3 NP_698231.1 1196525 R 204722 CDS NP_698232.1 23502105 1166904 complement(1197235..1197624) 1 NC_004310.3 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 1197624 rplV 1166904 rplV Brucella suis 1330 50S ribosomal protein L22 NP_698232.1 1197235 R 204722 CDS NP_698233.1 23502106 1166905 complement(1197627..1197905) 1 NC_004310.3 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 1197905 rpsS 1166905 rpsS Brucella suis 1330 30S ribosomal protein S19 NP_698233.1 1197627 R 204722 CDS NP_698234.1 23502107 1166906 complement(1197921..1198754) 1 NC_004310.3 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 1198754 rplB 1166906 rplB Brucella suis 1330 50S ribosomal protein L2 NP_698234.1 1197921 R 204722 CDS NP_698235.1 23502108 1166907 complement(1198776..1199069) 1 NC_004310.3 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 1199069 rplW 1166907 rplW Brucella suis 1330 50S ribosomal protein L23 NP_698235.1 1198776 R 204722 CDS NP_698236.1 23502109 1166908 complement(1199066..1199686) 1 NC_004310.3 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 1199686 rplD 1166908 rplD Brucella suis 1330 50S ribosomal protein L4 NP_698236.1 1199066 R 204722 CDS NP_698237.1 23502110 1166909 complement(1199686..1200399) 1 NC_004310.3 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 1200399 rplC 1166909 rplC Brucella suis 1330 50S ribosomal protein L3 NP_698237.1 1199686 R 204722 CDS NP_698238.1 23502111 1166910 complement(1200429..1200737) 1 NC_004310.3 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 1200737 rpsJ 1166910 rpsJ Brucella suis 1330 30S ribosomal protein S10 NP_698238.1 1200429 R 204722 CDS NP_698239.1 23502112 1166911 complement(1200798..1201973) 1 NC_004310.3 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1201973 tuf 1166911 tuf Brucella suis 1330 elongation factor Tu NP_698239.1 1200798 R 204722 CDS NP_698240.1 23502113 1166912 complement(1202037..1204121) 1 NC_004310.3 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 1204121 fusA 1166912 fusA Brucella suis 1330 elongation factor G NP_698240.1 1202037 R 204722 CDS NP_698241.1 23502114 1166913 complement(1204152..1204622) 1 NC_004310.3 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 1204622 rpsG 1166913 rpsG Brucella suis 1330 30S ribosomal protein S7 NP_698241.1 1204152 R 204722 CDS NP_698242.1 23502115 1166914 complement(1204689..1205060) 1 NC_004310.3 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 1205060 rpsL 1166914 rpsL Brucella suis 1330 30S ribosomal protein S12 NP_698242.1 1204689 R 204722 CDS NP_698243.1 23502116 1166915 complement(1205150..1205284) 1 NC_004310.3 hypothetical protein 1205284 1166915 BR1239 Brucella suis 1330 hypothetical protein NP_698243.1 1205150 R 204722 CDS NP_698244.1 23502117 1166916 complement(1205291..1205395) 1 NC_004310.3 hypothetical protein 1205395 1166916 BR1240 Brucella suis 1330 hypothetical protein NP_698244.1 1205291 R 204722 CDS NP_698245.1 23502118 1166917 1205492..1205863 1 NC_004310.3 identified by similarity to GP:15074283; hypothetical protein 1205863 1166917 BR1241 Brucella suis 1330 hypothetical protein NP_698245.1 1205492 D 204722 CDS NP_698246.1 23502119 1166918 complement(1205970..1210172) 1 NC_004310.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 1210172 rpoC 1166918 rpoC Brucella suis 1330 DNA-directed RNA polymerase subunit beta' NP_698246.1 1205970 R 204722 CDS NP_698247.1 23502120 1166919 complement(1210321..1214454) 1 NC_004310.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 1214454 rpoB 1166919 rpoB Brucella suis 1330 DNA-directed RNA polymerase subunit beta NP_698247.1 1210321 R 204722 CDS NP_698248.1 23502121 1166920 1214440..1214544 1 NC_004310.3 hypothetical protein 1214544 1166920 BR1244 Brucella suis 1330 hypothetical protein NP_698248.1 1214440 D 204722 CDS NP_698249.1 23502122 1166921 complement(1214662..1215036) 1 NC_004310.3 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 1215036 rplL 1166921 rplL Brucella suis 1330 50S ribosomal protein L7/L12 NP_698249.1 1214662 R 204722 CDS NP_698250.1 23502123 1166922 complement(1215088..1215606) 1 NC_004310.3 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 1215606 rplJ 1166922 rplJ Brucella suis 1330 50S ribosomal protein L10 NP_698250.1 1215088 R 204722 CDS NP_698251.1 23502124 1166923 complement(1215997..1216698) 1 NC_004310.3 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 1216698 rplA 1166923 rplA Brucella suis 1330 50S ribosomal protein L1 NP_698251.1 1215997 R 204722 CDS NP_698252.1 23502125 1166924 complement(1216703..1217131) 1 NC_004310.3 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 1217131 rplK 1166924 rplK Brucella suis 1330 50S ribosomal protein L11 NP_698252.1 1216703 R 204722 CDS NP_698253.1 23502126 1166925 complement(1217334..1217861) 1 NC_004310.3 Modulates Rho-dependent transcription termination; transcription antitermination protein NusG 1217861 nusG 1166925 nusG Brucella suis 1330 transcription antitermination protein NusG NP_698253.1 1217334 R 204722 CDS NP_698254.1 23502127 1166926 complement(1217885..1218124) 1 NC_004310.3 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 1218124 secE 1166926 secE Brucella suis 1330 preprotein translocase subunit SecE NP_698254.1 1217885 R 204722 CDS NP_698255.1 23502128 1166928 complement(1218758..1219933) 1 NC_004310.3 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 1219933 tuf 1166928 tuf Brucella suis 1330 elongation factor Tu NP_698255.1 1218758 R 204722 CDS NP_698256.1 23502129 1166929 1219884..1220084 1 NC_004310.3 hypothetical protein 1220084 1166929 BR1252 Brucella suis 1330 hypothetical protein NP_698256.1 1219884 D 204722 CDS NP_698257.1 23502130 1166932 complement(1220316..1220432) 1 NC_004310.3 hypothetical protein 1220432 1166932 BR1253 Brucella suis 1330 hypothetical protein NP_698257.1 1220316 R 204722 CDS NP_698258.1 23502131 1166933 1220564..1221424 1 NC_004310.3 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; RNA methyltransferase 1221424 1166933 BR1254 Brucella suis 1330 RNA methyltransferase NP_698258.1 1220564 D 204722 CDS NP_698259.1 23502132 1166935 complement(1222086..1222847) 1 NC_004310.3 identified by match to protein family HMM PF01694; rhomboid family protein 1222847 1166935 BR1256 Brucella suis 1330 rhomboid family protein NP_698259.1 1222086 R 204722 CDS NP_698260.1 23502133 1166936 1222908..1223003 1 NC_004310.3 hypothetical protein 1223003 1166936 BR1257 Brucella suis 1330 hypothetical protein NP_698260.1 1222908 D 204722 CDS NP_698261.1 23502134 1166937 1223185..1223847 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0144; hypothetical protein 1223847 1166937 BR1258 Brucella suis 1330 hypothetical protein NP_698261.1 1223185 D 204722 CDS NP_698262.1 23502135 1166938 1224091..1224696 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0142; hypothetical protein 1224696 1166938 BR1259 Brucella suis 1330 hypothetical protein NP_698262.1 1224091 D 204722 CDS NP_698263.1 23502136 1166939 complement(1224775..1225302) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0140; match to protein family HMM PF00132; ferripyochelin-binding protein 1225302 1166939 BR1260 Brucella suis 1330 ferripyochelin-binding protein NP_698263.1 1224775 R 204722 CDS NP_698264.1 23502137 1166940 complement(1225573..1225827) 1 NC_004310.3 identified by similarity to GP:15074417; hypothetical protein 1225827 1166940 BR1261 Brucella suis 1330 hypothetical protein NP_698264.1 1225573 R 204722 CDS NP_698265.1 23502138 1166941 complement(1226075..1226875) 1 NC_004310.3 identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine acetyltransferase 1226875 cysE 1166941 cysE Brucella suis 1330 serine acetyltransferase NP_698265.1 1226075 R 204722 CDS NP_698266.1 23502139 1166942 1226915..1227037 1 NC_004310.3 hypothetical protein 1227037 1166942 BR1263 Brucella suis 1330 hypothetical protein NP_698266.1 1226915 D 204722 CDS NP_698267.1 23502140 1166943 complement(1227074..1227844) 1 NC_004310.3 identified by match to protein family HMM PF00561; alpha/beta hydrolase 1227844 1166943 BR1264 Brucella suis 1330 alpha/beta hydrolase NP_698267.1 1227074 R 204722 CDS NP_698268.1 23502141 1166944 complement(1227878..1228357) 1 NC_004310.3 identified by similarity to GP:14021198; match to protein family HMM PF02643; hypothetical protein 1228357 1166944 BR1265 Brucella suis 1330 hypothetical protein NP_698268.1 1227878 R 204722 CDS NP_698269.1 23502142 1166945 complement(1228731..1229312) 1 NC_004310.3 identified by match to protein family HMM PF00313; cold-shock family protein 1229312 1166945 BR1266 Brucella suis 1330 cold-shock family protein NP_698269.1 1228731 R 204722 CDS NP_698270.1 23502143 1166946 complement(1229436..1229606) 1 NC_004310.3 hypothetical protein 1229606 1166946 BR1267 Brucella suis 1330 hypothetical protein NP_698270.1 1229436 R 204722 CDS NP_698271.1 23502144 1166947 1229675..1230115 1 NC_004310.3 identified by match to protein family HMM PF00903; lactoylglutathione lyase 1230115 gloA 1166947 gloA Brucella suis 1330 lactoylglutathione lyase NP_698271.1 1229675 D 204722 CDS NP_698272.1 23502145 1166948 complement(1230167..1231195) 1 NC_004310.3 identified by similarity to OMNI:NT01MC4682; hypothetical protein 1231195 1166948 BR1269 Brucella suis 1330 hypothetical protein NP_698272.1 1230167 R 204722 CDS NP_698273.1 23502146 1166949 complement(1231357..1233141) 1 NC_004310.3 identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ 1233141 recJ 1166949 recJ Brucella suis 1330 single-stranded-DNA-specific exonuclease RecJ NP_698273.1 1231357 R 204722 CDS NP_698274.1 23502147 1166950 complement(1233191..1234252) 1 NC_004310.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A 1234252 ddl 1166950 ddl Brucella suis 1330 D-alanyl-alanine synthetase A NP_698274.1 1233191 R 204722 CDS NP_698275.1 23502148 1166951 1234281..1234421 1 NC_004310.3 hypothetical protein 1234421 1166951 BR1272 Brucella suis 1330 hypothetical protein NP_698275.1 1234281 D 204722 CDS NP_698276.1 23502149 1166952 complement(1234600..1235586) 1 NC_004310.3 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 1235586 glpX 1166952 glpX Brucella suis 1330 fructose 1,6-bisphosphatase II NP_698276.1 1234600 R 204722 CDS NP_698277.1 23502150 1166953 complement(1235979..1237298) 1 NC_004310.3 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 1237298 hom 1166953 hom Brucella suis 1330 homoserine dehydrogenase NP_698277.1 1235979 R 204722 CDS NP_698278.1 23502151 1166954 complement(1237434..1238654) 1 NC_004310.3 identified by match to protein family HMM PF00155; aminotransferase 1238654 1166954 BR1275 Brucella suis 1330 aminotransferase NP_698278.1 1237434 R 204722 CDS NP_698279.1 23502152 1166955 complement(1238785..1239216) 1 NC_004310.3 hypothetical protein 1239216 1166955 BR1276 Brucella suis 1330 hypothetical protein NP_698279.1 1238785 R 204722 CDS NP_698280.1 23502153 1166956 1239621..1240901 1 NC_004310.3 identified by similarity to GP:14021808; hypothetical protein 1240901 1166956 BR1277 Brucella suis 1330 hypothetical protein NP_698280.1 1239621 D 204722 CDS NP_698281.1 23502154 1166959 1241512..1241796 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0128; hypothetical protein 1241796 1166959 BR1278 Brucella suis 1330 hypothetical protein NP_698281.1 1241512 D 204722 CDS NP_698282.1 23502155 1166960 1241930..1242022 1 NC_004310.3 hypothetical protein 1242022 1166960 BR1279 Brucella suis 1330 hypothetical protein NP_698282.1 1241930 D 204722 CDS NP_698283.1 23502156 1166961 1242019..1242111 1 NC_004310.3 hypothetical protein 1242111 1166961 BR1280 Brucella suis 1330 hypothetical protein NP_698283.1 1242019 D 204722 CDS NP_698284.1 23502157 1166962 1242120..1242836 1 NC_004310.3 Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1242836 sfsA 1166962 sfsA Brucella suis 1330 sugar fermentation stimulation protein A NP_698284.1 1242120 D 204722 CDS NP_698285.1 23502158 1166963 1242836..1243663 1 NC_004310.3 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1243663 map 1166963 map Brucella suis 1330 methionine aminopeptidase NP_698285.1 1242836 D 204722 CDS NP_698286.1 23502159 1166964 1243719..1244468 1 NC_004310.3 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1244468 radC 1166964 radC Brucella suis 1330 DNA repair protein RadC NP_698286.1 1243719 D 204722 CDS NP_698287.1 23502160 1166965 1244670..1245308 1 NC_004310.3 identified by similarity to GP:14018349; hypothetical protein 1245308 1166965 BR1284 Brucella suis 1330 hypothetical protein NP_698287.1 1244670 D 204722 CDS NP_698288.1 23502161 1166966 complement(1245597..1246802) 1 NC_004310.3 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01468; precorrin-6Y C5,15-methyltransferase 1246802 cobL 1166966 cobL Brucella suis 1330 precorrin-6Y C5,15-methyltransferase NP_698288.1 1245597 R 204722 CDS NP_698289.1 23502162 1166967 1246876..1248171 1 NC_004310.3 identified by match to protein family HMM PF01077; match to protein family HMM PF03460; nitrite reductase 1248171 1166967 BR1286 Brucella suis 1330 nitrite reductase NP_698289.1 1246876 D 204722 CDS NP_698290.1 23502163 1166968 1248181..1248807 1 NC_004310.3 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 1248807 cobH 1166968 cobH Brucella suis 1330 precorrin-8X methylmutase NP_698290.1 1248181 D 204722 CDS NP_698291.1 23502164 1166969 1248807..1249541 1 NC_004310.3 catalyzes the formation of precorrin-3 from precorrin-2; precorrin-2 C20-methyltransferase 1249541 cobI 1166969 cobI Brucella suis 1330 precorrin-2 C20-methyltransferase NP_698291.1 1248807 D 204722 CDS NP_698292.1 23502165 1166970 1249487..1251232 1 NC_004310.3 identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466; cbiG protein/precorrin-3B C17-methyltransferase 1251232 1166970 BR1289 Brucella suis 1330 cbiG protein/precorrin-3B C17-methyltransferase NP_698292.1 1249487 D 204722 CDS NP_698293.1 23502166 1166971 complement(1251288..1251755) 1 NC_004310.3 hypothetical protein 1251755 1166971 BR1290 Brucella suis 1330 hypothetical protein NP_698293.1 1251288 R 204722 CDS NP_698294.1 23502167 1166972 complement(1251880..1252776) 1 NC_004310.3 phospholipase/carboxylesterase 1252776 1166972 BR1291 Brucella suis 1330 phospholipase/carboxylesterase NP_698294.1 1251880 R 204722 CDS NP_698295.1 23502168 1166973 complement(1252780..1253301) 1 NC_004310.3 identified by match to protein family HMM PF01613; monooxygenase 1253301 1166973 BR1292 Brucella suis 1330 monooxygenase NP_698295.1 1252780 R 204722 CDS NP_698296.1 23502169 1166974 1253446..1254537 1 NC_004310.3 identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1254537 1166974 BR1293 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_698296.1 1253446 D 204722 CDS NP_698297.1 23502170 1166975 complement(1254523..1255518) 1 NC_004310.3 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein 1255518 cobD 1166975 cobD Brucella suis 1330 cobalamin biosynthesis protein NP_698297.1 1254523 R 204722 CDS NP_698298.1 23502171 1166976 complement(1255543..1256541) 1 NC_004310.3 identified by similarity to SP:P21633; match to protein family HMM PF00155; cobC protein 1256541 cobC 1166976 cobC Brucella suis 1330 cobC protein NP_698298.1 1255543 R 204722 CDS NP_698299.1 23502172 1166977 complement(1256538..1257848) 1 NC_004310.3 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase 1257848 cobB 1166977 cobB Brucella suis 1330 cobyrinic acid a,c-diamide synthase NP_698299.1 1256538 R 204722 CDS NP_698300.1 23502173 1166978 complement(1257845..1258693) 1 NC_004310.3 identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; uroporphyrin-III C-methyltransferase 1258693 cobA 1166978 cobA Brucella suis 1330 uroporphyrin-III C-methyltransferase NP_698300.1 1257845 R 204722 CDS NP_698301.1 23502174 1166979 1258784..1259890 1 NC_004310.3 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1259890 cbiD 1166979 cbiD Brucella suis 1330 cobalt-precorrin-6A synthase NP_698301.1 1258784 D 204722 CDS NP_698302.1 23502175 1166980 1259877..1260623 1 NC_004310.3 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1260623 cobK 1166980 cobK Brucella suis 1330 cobalt-precorrin-6x reductase NP_698302.1 1259877 D 204722 CDS NP_698303.1 23502176 1166981 complement(1260612..1261370) 1 NC_004310.3 identified by similarity to SP:P21922; match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C11-methyltransferase 1261370 cobM 1166981 cobM Brucella suis 1330 precorrin-4 C11-methyltransferase NP_698303.1 1260612 R 204722 CDS NP_698304.1 23502177 1166982 complement(1261430..1261825) 1 NC_004310.3 precorrin-3B C17-methyltransferase 1261825 1166982 BR1301 Brucella suis 1330 precorrin-3B C17-methyltransferase NP_698304.1 1261430 R 204722 CDS NP_698305.1 23502178 1166983 complement(1261818..1262264) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0945; hypothetical protein 1262264 1166983 BR1302 Brucella suis 1330 hypothetical protein NP_698305.1 1261818 R 204722 CDS NP_698306.1 23502179 1166984 1262424..1263209 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0946; match to protein family HMM PF01925; hypothetical protein 1263209 1166984 BR1303 Brucella suis 1330 hypothetical protein NP_698306.1 1262424 D 204722 CDS NP_698307.1 23502180 1166985 complement(1263206..1263634) 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 1263634 1166985 BR1304 Brucella suis 1330 hypothetical protein NP_698307.1 1263206 R 204722 CDS NP_698308.1 23502181 1166986 complement(1263634..1264242) 1 NC_004310.3 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase 1264242 cobO 1166986 cobO Brucella suis 1330 cob(I)yrinic acid a,c-diamide adenosyltransferase NP_698308.1 1263634 R 204722 CDS NP_698309.1 23502182 1166987 complement(1264265..1268056) 1 NC_004310.3 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN 1268056 cobN 1166987 cobN Brucella suis 1330 cobaltochelatase subunit CobN NP_698309.1 1264265 R 204722 CDS NP_698310.1 23502183 1166988 complement(1268056..1269105) 1 NC_004310.3 identified by match to protein family HMM PF02492; cobW protein 1269105 1166988 BR1307 Brucella suis 1330 cobW protein NP_698310.1 1268056 R 204722 CDS NP_698311.1 23502184 1166989 complement(1269109..1269630) 1 NC_004310.3 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase 1269630 cobU 1166989 cobU Brucella suis 1330 adenosylcobinamide kinase NP_698311.1 1269109 R 204722 CDS NP_698312.1 23502185 1166990 complement(1269636..1270352) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1033; hypothetical protein 1270352 1166990 BR1309 Brucella suis 1330 hypothetical protein NP_698312.1 1269636 R 204722 CDS NP_698313.1 23502186 1166991 complement(1270441..1270629) 1 NC_004310.3 identified by similarity to GP:14022104; hypothetical protein 1270629 1166991 BR1310 Brucella suis 1330 hypothetical protein NP_698313.1 1270441 R 204722 CDS NP_698314.1 23502187 1166992 complement(1270943..1272394) 1 NC_004310.3 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase 1272394 cobQ 1166992 cobQ Brucella suis 1330 cobyric acid synthase NP_698314.1 1270943 R 204722 CDS NP_698315.1 23502188 1166993 complement(1272405..1272554) 1 NC_004310.3 hypothetical protein 1272554 1166993 BR1312 Brucella suis 1330 hypothetical protein NP_698315.1 1272405 R 204722 CDS NP_698316.1 23502189 1166995 1273859..1274749 1 NC_004310.3 identified by match to protein family HMM PF03446; match to protein family HMM TIGR01692; 3-hydroxyisobutyrate dehydrogenase 1274749 mmsB 1166995 mmsB Brucella suis 1330 3-hydroxyisobutyrate dehydrogenase NP_698316.1 1273859 D 204722 CDS NP_698317.1 23502190 1166996 complement(1274985..1275152) 1 NC_004310.3 hypothetical protein 1275152 1166996 BR1315 Brucella suis 1330 hypothetical protein NP_698317.1 1274985 R 204722 CDS NP_698318.1 23502191 1166997 complement(1275145..1275279) 1 NC_004310.3 identified by similarity to OMNI:CC3473; hypothetical protein 1275279 1166997 BR1316 Brucella suis 1330 hypothetical protein NP_698318.1 1275145 R 204722 CDS NP_698319.1 23502192 1166998 complement(1275347..1275448) 1 NC_004310.3 hypothetical protein 1275448 1166998 BR1317 Brucella suis 1330 hypothetical protein NP_698319.1 1275347 R 204722 CDS NP_698320.1 23502193 1167000 1276826..1277824 1 NC_004310.3 identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 1277824 1167000 BR1319 Brucella suis 1330 AraC family transcriptional regulator NP_698320.1 1276826 D 204722 CDS NP_698321.1 23502194 1167002 complement(1280737..1281027) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1001; hypothetical protein 1281027 1167002 BR1321 Brucella suis 1330 hypothetical protein NP_698321.1 1280737 R 204722 CDS NP_698322.1 23502195 1167004 complement(1283839..1284423) 1 NC_004310.3 hypothetical protein 1284423 1167004 BR1323 Brucella suis 1330 hypothetical protein NP_698322.1 1283839 R 204722 CDS NP_698323.1 23502196 1167005 1284475..1287012 1 NC_004310.3 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1287012 1167005 BR1324 Brucella suis 1330 bifunctional preprotein translocase subunit SecD/SecF NP_698323.1 1284475 D 204722 CDS NP_698324.1 23502197 1167006 1287090..1288949 1 NC_004310.3 identified by match to protein family HMM PF00999; match to protein family HMM PF02254; match to protein family HMM TIGR00932; potassium efflux system family protein 1288949 1167006 BR1325 Brucella suis 1330 potassium efflux system family protein NP_698324.1 1287090 D 204722 CDS NP_698325.1 23502198 1167007 1288949..1289920 1 NC_004310.3 hypothetical protein 1289920 1167007 BR1326 Brucella suis 1330 hypothetical protein NP_698325.1 1288949 D 204722 CDS NP_698326.1 23502199 1167008 1290147..1290752 1 NC_004310.3 identified by similarity to GP:15074696; hypothetical protein 1290752 1167008 BR1327 Brucella suis 1330 hypothetical protein NP_698326.1 1290147 D 204722 CDS NP_698327.1 23502200 1167009 complement(1290798..1291628) 1 NC_004310.3 identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease 1291628 cysW-2 1167009 cysW-2 Brucella suis 1330 sulfate ABC transporter permease NP_698327.1 1290798 R 204722 CDS NP_698328.1 23502201 1167010 complement(1291615..1292481) 1 NC_004310.3 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease 1292481 1167010 BR1329 Brucella suis 1330 sulfate ABC transporter permease NP_698328.1 1291615 R 204722 CDS NP_698329.1 23502202 1167011 complement(1292608..1293612) 1 NC_004310.3 identified by similarity to SP:P06997; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter sulfate-binding protein 1293612 1167011 BR1330 Brucella suis 1330 sulfate ABC transporter sulfate-binding protein NP_698329.1 1292608 R 204722 CDS NP_698330.1 23502203 1167012 complement(1293878..1294063) 1 NC_004310.3 hypothetical protein 1294063 1167012 BR1331 Brucella suis 1330 hypothetical protein NP_698330.1 1293878 R 204722 CDS NP_698331.1 23502204 1167013 complement(1294243..1295799) 1 NC_004310.3 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; CBS domain-containing protein 1295799 1167013 BR1332 Brucella suis 1330 CBS domain-containing protein NP_698331.1 1294243 R 204722 CDS NP_698332.1 23502205 1167014 complement(1296229..1296891) 1 NC_004310.3 identified by match to protein family HMM PF00597; dedA family protein 1296891 1167014 BR1333 Brucella suis 1330 dedA family protein NP_698332.1 1296229 R 204722 CDS NP_698333.1 23502206 1167015 1296967..1297062 1 NC_004310.3 hypothetical protein 1297062 1167015 BR1334 Brucella suis 1330 hypothetical protein NP_698333.1 1296967 D 204722 CDS NP_698334.1 23502207 1167016 1297299..1297505 1 NC_004310.3 hypothetical protein 1297505 1167016 BR1335 Brucella suis 1330 hypothetical protein NP_698334.1 1297299 D 204722 CDS NP_698335.1 23502208 1167018 1297774..1298328 1 NC_004310.3 identified by similarity to EGAD:154080; match to protein family HMM PF00036; acid-shock protein 1298328 1167018 BR1336 Brucella suis 1330 acid-shock protein NP_698335.1 1297774 D 204722 CDS NP_698336.1 23502209 1167019 complement(1298462..1298884) 1 NC_004310.3 identified by match to protein family HMM PF05025; fucose operon fucU protein 1298884 fucU 1167019 fucU Brucella suis 1330 fucose operon fucU protein NP_698336.1 1298462 R 204722 CDS NP_698337.1 23502210 1167020 complement(1298978..1299787) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3842; match to protein family HMM PF00106; short chain dehydrogenase 1299787 1167020 BR1338 Brucella suis 1330 short chain dehydrogenase NP_698337.1 1298978 R 204722 CDS NP_698338.1 23502211 1167021 complement(1299802..1300581) 1 NC_004310.3 identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein 1300581 1167021 BR1339 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_698338.1 1299802 R 204722 CDS NP_698339.1 23502212 1167022 complement(1300595..1301722) 1 NC_004310.3 identified by similarity to GP:6273663; match to protein family HMM PF02653; sugar ABC transporter permease 1301722 1167022 BR1340 Brucella suis 1330 sugar ABC transporter permease NP_698339.1 1300595 R 204722 CDS NP_698340.1 23502213 1167023 complement(1301755..1301847) 1 NC_004310.3 hypothetical protein 1301847 1167023 BR1341 Brucella suis 1330 hypothetical protein NP_698340.1 1301755 R 204722 CDS NP_698341.1 23502214 1167024 complement(1302009..1302938) 1 NC_004310.3 identified by similarity to GP:6273662; match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein 1302938 1167024 BR1342 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_698341.1 1302009 R 204722 CDS NP_698342.1 23502215 1167025 1303317..1304432 1 NC_004310.3 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1304432 1167025 BR1343 Brucella suis 1330 oxidoreductase NP_698342.1 1303317 D 204722 CDS NP_698343.1 23502216 1167026 complement(1304429..1305205) 1 NC_004310.3 identified by similarity to SP:P15031; match to protein family HMM PF00005; iron ABC transporter ATP-binding protein 1305205 1167026 BR1344 Brucella suis 1330 iron ABC transporter ATP-binding protein NP_698343.1 1304429 R 204722 CDS NP_698344.1 23502217 1167027 complement(1305202..1306203) 1 NC_004310.3 identified by match to protein family HMM PF01032; iron ABC transporter permease 1306203 1167027 BR1345 Brucella suis 1330 iron ABC transporter permease NP_698344.1 1305202 R 204722 CDS NP_698345.1 23502218 1167028 complement(1306196..1307035) 1 NC_004310.3 identified by similarity to PIR:S54437; match to protein family HMM PF01497; iron ABC transporter substrate-binding protein 1307035 1167028 BR1346 Brucella suis 1330 iron ABC transporter substrate-binding protein NP_698345.1 1306196 R 204722 CDS NP_698346.1 23502219 1167029 complement(1307049..1308911) 1 NC_004310.3 identified by similarity to SP:P06129; match to protein family HMM PF00593; iron compound TonB-dependent receptor 1308911 1167029 BR1347 Brucella suis 1330 iron compound TonB-dependent receptor NP_698346.1 1307049 R 204722 CDS NP_698347.1 23502220 1167030 complement(1309200..1309355) 1 NC_004310.3 hypothetical protein 1309355 1167030 BR1348 Brucella suis 1330 hypothetical protein NP_698347.1 1309200 R 204722 CDS NP_698348.1 23502221 1167031 complement(1309405..1310517) 1 NC_004310.3 ABC transporter permease 1310517 1167031 BR1349 Brucella suis 1330 ABC transporter permease NP_698348.1 1309405 R 204722 CDS NP_698349.1 23502222 1167032 complement(1310519..1313287) 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP binding/permease 1313287 1167032 BR1350 Brucella suis 1330 ABC transporter ATP binding/permease NP_698349.1 1310519 R 204722 CDS NP_698350.1 23502223 1167033 complement(1313284..1314351) 1 NC_004310.3 identified by match to protein family HMM PF00529; HlyD family secretion protein 1314351 1167033 BR1351 Brucella suis 1330 HlyD family secretion protein NP_698350.1 1313284 R 204722 CDS NP_698351.1 23502224 1167034 1314331..1314510 1 NC_004310.3 hypothetical protein 1314510 1167034 BR1352 Brucella suis 1330 hypothetical protein NP_698351.1 1314331 D 204722 CDS NP_698352.1 23502225 1167035 complement(1314588..1314851) 1 NC_004310.3 hypothetical protein 1314851 1167035 BR1353 Brucella suis 1330 hypothetical protein NP_698352.1 1314588 R 204722 CDS NP_698353.1 23502226 1167036 complement(1314896..1316191) 1 NC_004310.3 identified by similarity to OMNI:NTL02EC1981; match to protein family HMM PF02638; hypothetical protein 1316191 1167036 BR1354 Brucella suis 1330 hypothetical protein NP_698353.1 1314896 R 204722 CDS NP_698354.1 23502227 1167037 complement(1316770..1316946) 1 NC_004310.3 hypothetical protein 1316946 1167037 BR1355 Brucella suis 1330 hypothetical protein NP_698354.1 1316770 R 204722 CDS NP_698355.1 23502228 1167038 1317006..1317308 1 NC_004310.3 UreA, with UreB and UreC, catalyzes the hydrolysis of urea to ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1317308 ureA 1167038 ureA Brucella suis 1330 urease subunit gamma NP_698355.1 1317006 D 204722 CDS NP_698356.1 23502229 1167039 1317357..1317836 1 NC_004310.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) does not seem to be involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo; urease subunit beta 1317836 ureB 1167039 ureB Brucella suis 1330 urease subunit beta NP_698356.1 1317357 D 204722 CDS NP_698357.1 23502230 1167040 1317876..1319597 1 NC_004310.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1319597 ureC 1167040 ureC Brucella suis 1330 urease subunit alpha NP_698357.1 1317876 D 204722 CDS NP_698358.1 23502231 1167041 1319645..1320250 1 NC_004310.3 involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1320250 ureE 1167041 ureE Brucella suis 1330 urease accessory protein UreE NP_698358.1 1319645 D 204722 CDS NP_698359.1 23502232 1167042 1320222..1320953 1 NC_004310.3 identified by similarity to EGAD:8726; match to protein family HMM PF01730; urease accessory protein UreF 1320953 1167042 BR1360 Brucella suis 1330 urease accessory protein UreF NP_698359.1 1320222 D 204722 CDS NP_698360.1 23502233 1167043 1320969..1321607 1 NC_004310.3 identified by similarity to SP:P42871; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 1321607 ureG-2 1167043 ureG-2 Brucella suis 1330 urease accessory protein UreG NP_698360.1 1320969 D 204722 CDS NP_698361.1 23502234 1167044 1321607..1322515 1 NC_004310.3 identified by similarity to EGAD:20614; match to protein family HMM PF01774; urease accessory protein UreD 1322515 ureD-2 1167044 ureD-2 Brucella suis 1330 urease accessory protein UreD NP_698361.1 1321607 D 204722 CDS NP_698362.1 23502235 1167045 1322525..1323577 1 NC_004310.3 identified by similarity to GP:1905970; match to protein family HMM PF03253; urea transporter 1323577 1167045 BR1363 Brucella suis 1330 urea transporter NP_698362.1 1322525 D 204722 CDS NP_698363.1 23502236 1167046 1323604..1324362 1 NC_004310.3 lipoprotein 1324362 1167046 BR1364 Brucella suis 1330 lipoprotein NP_698363.1 1323604 D 204722 CDS NP_698364.1 23502237 1167047 1324382..1325017 1 NC_004310.3 catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1325017 cbiM 1167047 cbiM Brucella suis 1330 cobalt transport protein CbiM NP_698364.1 1324382 D 204722 CDS NP_698365.1 23502238 1167048 1325014..1325640 1 NC_004310.3 identified by similarity to EGAD:28613; hypothetical protein 1325640 1167048 BR1366 Brucella suis 1330 hypothetical protein NP_698365.1 1325014 D 204722 CDS NP_698366.1 23502239 1167049 1325637..1326401 1 NC_004310.3 identified by similarity to GP:6138845; match to protein family HMM PF02361; cobalt ABC transporter permease 1326401 1167049 BR1367 Brucella suis 1330 cobalt ABC transporter permease NP_698366.1 1325637 D 204722 CDS NP_698367.1 23502240 1167050 1326398..1327117 1 NC_004310.3 identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 1327117 1167050 BR1368 Brucella suis 1330 cobalt ABC transporter ATP-binding protein NP_698367.1 1326398 D 204722 CDS NP_698368.1 23502241 1167051 complement(1327138..1327902) 1 NC_004310.3 identified by match to protein family HMM PF02537; match to protein family HMM PF03625; crcB family protein 1327902 1167051 BR1369 Brucella suis 1330 crcB family protein NP_698368.1 1327138 R 204722 CDS NP_698369.1 23502242 1167052 complement(1327963..1328352) 1 NC_004310.3 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 1328352 ccrB 1167052 ccrB Brucella suis 1330 camphor resistance protein CrcB NP_698369.1 1327963 R 204722 CDS NP_698370.1 23502243 1167053 1328621..1329646 1 NC_004310.3 hypothetical protein 1329646 1167053 BR1371 Brucella suis 1330 hypothetical protein NP_698370.1 1328621 D 204722 CDS NP_698371.1 23502244 1167054 complement(1329778..1330212) 1 NC_004310.3 identified by similarity to EGAD:6639; hypothetical protein 1330212 1167054 BR1372 Brucella suis 1330 hypothetical protein NP_698371.1 1329778 R 204722 CDS NP_698372.1 23502245 1167055 1330214..1330351 1 NC_004310.3 hypothetical protein 1330351 1167055 BR1373 Brucella suis 1330 hypothetical protein NP_698372.1 1330214 D 204722 CDS NP_698373.1 23502246 1167056 complement(1330364..1331290) 1 NC_004310.3 identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein 1331290 1167056 BR1374 Brucella suis 1330 PhzF family phenazine biosynthesis protein NP_698373.1 1330364 R 204722 CDS NP_698374.1 23502247 1167057 complement(1331395..1332057) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1103; hypothetical protein 1332057 1167057 BR1375 Brucella suis 1330 hypothetical protein NP_698374.1 1331395 R 204722 CDS NP_698375.1 23502248 1167059 1333258..1333773 1 NC_004310.3 identified by similarity to GP:3236220; hypothetical protein 1333773 1167059 BR1377 Brucella suis 1330 hypothetical protein NP_698375.1 1333258 D 204722 CDS NP_698376.1 23502249 1167060 complement(1333819..1335051) 1 NC_004310.3 identified by match to protein family HMM PF00155; class I aminotransferase 1335051 1167060 BR1378 Brucella suis 1330 class I aminotransferase NP_698376.1 1333819 R 204722 CDS NP_698377.1 23502250 1167061 complement(1335133..1335414) 1 NC_004310.3 hypothetical protein 1335414 1167061 BR1379 Brucella suis 1330 hypothetical protein NP_698377.1 1335133 R 204722 CDS NP_698378.1 23502251 1167062 complement(1335436..1336455) 1 NC_004310.3 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1336455 ilvC 1167062 ilvC Brucella suis 1330 ketol-acid reductoisomerase NP_698378.1 1335436 R 204722 CDS NP_698379.1 23502252 1167063 complement(1336511..1337152) 1 NC_004310.3 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1337152 1167063 BR1381 Brucella suis 1330 TetR family transcriptional regulator NP_698379.1 1336511 R 204722 CDS NP_698380.1 23502253 1167064 1337210..1337365 1 NC_004310.3 hypothetical protein 1337365 1167064 BR1382 Brucella suis 1330 hypothetical protein NP_698380.1 1337210 D 204722 CDS NP_698381.1 23502254 1167065 complement(1337362..1339317) 1 NC_004310.3 identified by similarity to SP:P30016; match to protein family HMM PF02705; potassium uptake protein 1339317 1167065 BR1383 Brucella suis 1330 potassium uptake protein NP_698381.1 1337362 R 204722 CDS NP_698382.1 23502255 1167066 complement(1339460..1339618) 1 NC_004310.3 hypothetical protein 1339618 1167066 BR1384 Brucella suis 1330 hypothetical protein NP_698382.1 1339460 R 204722 CDS NP_698383.1 23502256 1167067 complement(1339687..1340427) 1 NC_004310.3 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 1340427 1167067 BR1385 Brucella suis 1330 pyridoxine 5'-phosphate synthase NP_698383.1 1339687 R 204722 CDS NP_698384.1 23502257 1167068 1340724..1341125 1 NC_004310.3 hypothetical protein 1341125 1167068 BR1386 Brucella suis 1330 hypothetical protein NP_698384.1 1340724 D 204722 CDS NP_698385.1 23502258 1167069 complement(1341126..1342247) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1120; hypothetical protein 1342247 1167069 BR1387 Brucella suis 1330 hypothetical protein NP_698385.1 1341126 R 204722 CDS NP_698386.1 23502259 1167070 complement(1342431..1343003) 1 NC_004310.3 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 1343003 ilvH 1167070 ilvH Brucella suis 1330 acetolactate synthase 3 regulatory subunit NP_698386.1 1342431 R 204722 CDS NP_698387.1 23502260 1167071 complement(1343022..1344776) 1 NC_004310.3 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit 1344776 ilvB 1167071 ilvB Brucella suis 1330 acetolactate synthase 3 catalytic subunit NP_698387.1 1343022 R 204722 CDS NP_698388.1 23502261 1167072 complement(1345093..1346025) 1 NC_004310.3 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 1346025 miaA 1167072 miaA Brucella suis 1330 tRNA delta(2)-isopentenylpyrophosphate transferase NP_698388.1 1345093 R 204722 CDS NP_698389.1 23502262 1167073 1346043..1346942 1 NC_004310.3 identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488; phosphoserine phosphatase 1346942 serB 1167073 serB Brucella suis 1330 phosphoserine phosphatase NP_698389.1 1346043 D 204722 CDS NP_698390.1 23502263 1167074 complement(1346983..1348164) 1 NC_004310.3 identified by similarity to OMNI:CC1477; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein 1348164 1167074 BR1392 Brucella suis 1330 hypothetical protein NP_698390.1 1346983 R 204722 CDS NP_698391.1 23502264 1167075 complement(1348140..1348283) 1 NC_004310.3 hypothetical protein 1348283 1167075 BR1393 Brucella suis 1330 hypothetical protein NP_698391.1 1348140 R 204722 CDS NP_698392.1 23502265 1167076 complement(1348294..1349868) 1 NC_004310.3 identified by similarity to OMNI:CC2758; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease Do 1349868 1167076 BR1394 Brucella suis 1330 serine protease Do NP_698392.1 1348294 R 204722 CDS NP_698393.1 23502266 1167077 complement(1350092..1350277) 1 NC_004310.3 identified by similarity to GP:14022214; hypothetical protein 1350277 1167077 BR1395 Brucella suis 1330 hypothetical protein NP_698393.1 1350092 R 204722 CDS NP_698394.1 23502267 1167078 complement(1350297..1351199) 1 NC_004310.3 identified by similarity to EGAD:9363; match to protein family HMM PF01145; match to protein family HMM TIGR01932; hflC protein 1351199 hflC 1167078 hflC Brucella suis 1330 hflC protein NP_698394.1 1350297 R 204722 CDS NP_698395.1 23502268 1167079 complement(1351199..1352347) 1 NC_004310.3 identified by similarity to SP:Q9KV09; match to protein family HMM PF01145; match to protein family HMM TIGR01933; hflK protein 1352347 hflK 1167079 hflK Brucella suis 1330 hflK protein NP_698395.1 1351199 R 204722 CDS NP_698396.1 23502269 1167080 complement(1352472..1352990) 1 NC_004310.3 identified by match to protein family HMM PF00186; dihydrofolate reductase 1352990 folA 1167080 folA Brucella suis 1330 dihydrofolate reductase NP_698396.1 1352472 R 204722 CDS NP_698397.1 23502270 1167081 complement(1352993..1353787) 1 NC_004310.3 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1353787 thyA 1167081 thyA Brucella suis 1330 thymidylate synthase NP_698397.1 1352993 R 204722 CDS NP_698398.1 23502271 1167082 complement(1353888..1354199) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1156; hypothetical protein 1354199 1167082 BR1400 Brucella suis 1330 hypothetical protein NP_698398.1 1353888 R 204722 CDS NP_698399.1 23502272 1167083 complement(1354772..1355983) 1 NC_004310.3 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter 1355983 tcaB 1167083 tcaB Brucella suis 1330 Bcr/CflA subfamily drug resistance transporter NP_698399.1 1354772 R 204722 CDS NP_698400.1 23502273 1167084 complement(1356000..1356146) 1 NC_004310.3 hypothetical protein 1356146 1167084 BR1402 Brucella suis 1330 hypothetical protein NP_698400.1 1356000 R 204722 CDS NP_698401.1 23502274 1167085 1356278..1357003 1 NC_004310.3 identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1357003 1167085 BR1403 Brucella suis 1330 TetR family transcriptional regulator NP_698401.1 1356278 D 204722 CDS NP_698402.1 23502275 1167086 1357084..1357653 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1160; hypothetical protein 1357653 1167086 BR1404 Brucella suis 1330 hypothetical protein NP_698402.1 1357084 D 204722 CDS NP_698403.1 23502276 1167087 1357766..1357942 1 NC_004310.3 hypothetical protein 1357942 1167087 BR1405 Brucella suis 1330 hypothetical protein NP_698403.1 1357766 D 204722 CDS NP_698404.1 23502277 1167088 1358034..1358234 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1161; hypothetical protein 1358234 1167088 BR1406 Brucella suis 1330 hypothetical protein NP_698404.1 1358034 D 204722 CDS NP_698405.1 23502278 1167089 1358231..1358482 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1162; hypothetical protein 1358482 1167089 BR1407 Brucella suis 1330 hypothetical protein NP_698405.1 1358231 D 204722 CDS NP_698406.1 23502279 1167090 complement(1358510..1362253) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1167; match to protein family HMM PF05170; hypothetical protein 1362253 1167090 BR1408 Brucella suis 1330 hypothetical protein NP_698406.1 1358510 R 204722 CDS NP_698407.1 23502280 1167091 complement(1362308..1362448) 1 NC_004310.3 hypothetical protein 1362448 1167091 BR1409 Brucella suis 1330 hypothetical protein NP_698407.1 1362308 R 204722 CDS NP_698408.1 23502281 1167092 complement(1362445..1363851) 1 NC_004310.3 identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD-binding oxidoreductase 1363851 1167092 BR1410 Brucella suis 1330 FAD-binding oxidoreductase NP_698408.1 1362445 R 204722 CDS NP_698409.1 23502282 1167093 complement(1363876..1364385) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3966; hypothetical protein 1364385 1167093 BR1411 Brucella suis 1330 hypothetical protein NP_698409.1 1363876 R 204722 CDS NP_698410.1 23502283 1167094 1364505..1365581 1 NC_004310.3 identified by similarity to OMNI:NTL01XF00279; serine/threonine protein kinase 1365581 1167094 BR1412 Brucella suis 1330 serine/threonine protein kinase NP_698410.1 1364505 D 204722 CDS NP_698411.1 23502284 1167095 1365640..1368216 1 NC_004310.3 identified by similarity to EGAD:14237; match to protein family HMM PF00580; DNA helicase II 1368216 1167095 BR1413 Brucella suis 1330 DNA helicase II NP_698411.1 1365640 D 204722 CDS NP_698412.1 23502285 1167096 complement(1368290..1368787) 1 NC_004310.3 identified by similarity to GP:14022272; hypothetical protein 1368787 1167096 BR1414 Brucella suis 1330 hypothetical protein NP_698412.1 1368290 R 204722 CDS NP_698413.1 23502286 1167097 complement(1368852..1369541) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1201; match to protein family HMM PF00132; antibiotic acetyltransferase 1369541 1167097 BR1415 Brucella suis 1330 antibiotic acetyltransferase NP_698413.1 1368852 R 204722 CDS NP_698414.1 23502287 1167098 1369650..1370240 1 NC_004310.3 identified by match to protein family HMM PF02630; SCO1/SenC family protein 1370240 1167098 BR1416 Brucella suis 1330 SCO1/SenC family protein NP_698414.1 1369650 D 204722 CDS NP_698415.1 23502288 1167099 1370278..1371135 1 NC_004310.3 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1371135 prmA 1167099 prmA Brucella suis 1330 ribosomal protein L11 methyltransferase NP_698415.1 1370278 D 204722 CDS NP_698416.1 23502289 1167100 1371201..1373027 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1206; match to protein family HMM PF00557; aminopeptidase 1373027 1167100 BR1418 Brucella suis 1330 aminopeptidase NP_698416.1 1371201 D 204722 CDS NP_698417.1 23502290 1167101 complement(1373028..1373732) 1 NC_004310.3 identified by similarity to GP:14022279; hypothetical protein 1373732 1167101 BR1419 Brucella suis 1330 hypothetical protein NP_698417.1 1373028 R 204722 CDS NP_698418.1 23502291 1167102 complement(1373732..1375891) 1 NC_004310.3 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA 1375891 ligA 1167102 ligA Brucella suis 1330 NAD-dependent DNA ligase LigA NP_698418.1 1373732 R 204722 CDS NP_698419.1 23502292 1167103 complement(1376077..1377756) 1 NC_004310.3 identified by similarity to SP:P05824; match to protein family HMM TIGR00634; DNA repair protein RecN 1377756 recN 1167103 recN Brucella suis 1330 DNA repair protein RecN NP_698419.1 1376077 R 204722 CDS NP_698420.1 23502293 1167104 complement(1377769..1378632) 1 NC_004310.3 identified by similarity to EGAD:40678; match to protein family HMM PF03696; competence protein ComL 1378632 1167104 BR1422 Brucella suis 1330 competence protein ComL NP_698420.1 1377769 R 204722 CDS NP_698421.1 23502294 1167105 1378716..1378979 1 NC_004310.3 hypothetical protein 1378979 1167105 BR1423 Brucella suis 1330 hypothetical protein NP_698421.1 1378716 D 204722 CDS NP_698422.1 23502295 1167106 complement(1379039..1379899) 1 NC_004310.3 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 1379899 lpxC 1167106 lpxC Brucella suis 1330 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase NP_698422.1 1379039 R 204722 CDS NP_698423.1 23502296 1167107 complement(1380439..1382139) 1 NC_004310.3 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1382139 ftsZ 1167107 ftsZ Brucella suis 1330 cell division protein FtsZ NP_698423.1 1380439 R 204722 CDS NP_698424.1 23502297 1167108 complement(1382236..1383558) 1 NC_004310.3 identified by similarity to SP:O30994; match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA 1383558 ftsA 1167108 ftsA Brucella suis 1330 cell division protein FtsA NP_698424.1 1382236 R 204722 CDS NP_698425.1 23502298 1167109 complement(1383555..1384421) 1 NC_004310.3 identified by similarity to SP:O30993; match to protein family HMM PF03799; cell division protein FtsQ 1384421 1167109 BR1427 Brucella suis 1330 cell division protein FtsQ NP_698425.1 1383555 R 204722 CDS NP_698426.1 23502299 1167110 complement(1384478..1385404) 1 NC_004310.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 1385404 ddl 1167110 ddl Brucella suis 1330 D-alanine--D-alanine ligase NP_698426.1 1384478 R 204722 CDS NP_698427.1 23502300 1167111 complement(1385647..1386615) 1 NC_004310.3 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1386615 murB 1167111 murB Brucella suis 1330 UDP-N-acetylenolpyruvoylglucosamine reductase NP_698427.1 1385647 R 204722 CDS NP_698428.1 23502301 1167112 complement(1386615..1388030) 1 NC_004310.3 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 1388030 murC 1167112 murC Brucella suis 1330 UDP-N-acetylmuramate--L-alanine ligase NP_698428.1 1386615 R 204722 CDS NP_698429.1 23502302 1167113 complement(1388027..1389166) 1 NC_004310.3 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 1389166 murG 1167113 murG Brucella suis 1330 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_698429.1 1388027 R 204722 CDS NP_698430.1 23502303 1167114 complement(1389393..1390550) 1 NC_004310.3 identified by similarity to EGAD:20048; match to protein family HMM PF01098; cell division protein FtsW 1390550 ftsW 1167114 ftsW Brucella suis 1330 cell division protein FtsW NP_698430.1 1389393 R 204722 CDS NP_698431.1 23502304 1167115 complement(1390550..1391953) 1 NC_004310.3 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 1391953 murD 1167115 murD Brucella suis 1330 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_698431.1 1390550 R 204722 CDS NP_698432.1 23502305 1167116 complement(1391966..1393048) 1 NC_004310.3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1393048 mraY 1167116 mraY Brucella suis 1330 phospho-N-acetylmuramoyl-pentapeptide- transferase NP_698432.1 1391966 R 204722 CDS NP_698433.1 23502306 1167117 complement(1393075..1394520) 1 NC_004310.3 identified by similarity to EGAD:15807; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase 1394520 murF 1167117 murF Brucella suis 1330 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase NP_698433.1 1393075 R 204722 CDS NP_698434.1 23502307 1167118 complement(1394517..1395983) 1 NC_004310.3 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase 1395983 murE 1167118 murE Brucella suis 1330 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase NP_698434.1 1394517 R 204722 CDS NP_698435.1 23502308 1167119 complement(1396044..1397867) 1 NC_004310.3 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein 1397867 1167119 BR1437 Brucella suis 1330 penicillin-binding protein NP_698435.1 1396044 R 204722 CDS NP_698436.1 23502309 1167120 complement(1397870..1398271) 1 NC_004310.3 identified by similarity to GP:14022298; hypothetical protein 1398271 1167120 BR1438 Brucella suis 1330 hypothetical protein NP_698436.1 1397870 R 204722 CDS NP_698437.1 23502310 1167121 complement(1398276..1399316) 1 NC_004310.3 identified by similarity to GP:15075206; match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW 1399316 mraW 1167121 mraW Brucella suis 1330 S-adenosyl-methyltransferase MraW NP_698437.1 1398276 R 204722 CDS NP_698438.1 23502311 1167122 1399294..1399563 1 NC_004310.3 hypothetical protein 1399563 1167122 BR1440 Brucella suis 1330 hypothetical protein NP_698438.1 1399294 D 204722 CDS NP_698439.1 23502312 1167123 1399774..1401144 1 NC_004310.3 identified by similarity to GP:17740175; match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 1401144 1167123 BR1441 Brucella suis 1330 manganese transport protein MntH NP_698439.1 1399774 D 204722 CDS NP_698440.1 23502313 1167124 1401337..1401849 1 NC_004310.3 hypothetical protein 1401849 1167124 BR1442 Brucella suis 1330 hypothetical protein NP_698440.1 1401337 D 204722 CDS NP_698441.1 23502314 1167125 complement(1401846..1402490) 1 NC_004310.3 identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 1402490 1167125 BR1443 Brucella suis 1330 transglycosylase SLT domain-containing protein NP_698441.1 1401846 R 204722 CDS NP_698442.1 23502315 1167126 complement(1402831..1403637) 1 NC_004310.3 identified by match to protein family HMM PF01471; match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase 1403637 1167126 BR1444 Brucella suis 1330 N-acetylmuramoyl-L-alanine amidase NP_698442.1 1402831 R 204722 CDS NP_698443.1 23502316 1167127 complement(1403634..1404344) 1 NC_004310.3 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 1404344 1167127 BR1445 Brucella suis 1330 DnaJ domain-containing protein NP_698443.1 1403634 R 204722 CDS NP_698444.1 23502317 1167128 complement(1404464..1404868) 1 NC_004310.3 hypothetical protein 1404868 1167128 BR1446 Brucella suis 1330 hypothetical protein NP_698444.1 1404464 R 204722 CDS NP_698445.1 23502318 1167129 1405172..1406005 1 NC_004310.3 identified by match to protein family HMM PF01183; glycosyl hydrolase 1406005 1167129 BR1447 Brucella suis 1330 glycosyl hydrolase NP_698445.1 1405172 D 204722 CDS NP_698446.1 23502319 1167132 complement(1408788..1409699) 1 NC_004310.3 identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase 1409699 metF 1167132 metF Brucella suis 1330 5,10-methylenetetrahydrofolate reductase NP_698446.1 1408788 R 204722 CDS NP_698447.1 23502320 1167133 complement(1409745..1410770) 1 NC_004310.3 identified by match to protein family HMM PF01022; match to protein family HMM PF01209; ArsR family transcriptional regulator 1410770 1167133 BR1451 Brucella suis 1330 ArsR family transcriptional regulator NP_698447.1 1409745 R 204722 CDS NP_698448.1 23502321 1167134 1410890..1411213 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1250; hypothetical protein 1411213 1167134 BR1452 Brucella suis 1330 hypothetical protein NP_698448.1 1410890 D 204722 CDS NP_698449.1 23502322 1167135 complement(1411268..1412593) 1 NC_004310.3 identified by match to protein family HMM PF00083; match to protein family HMM TIGR00883; metabolite-proton symporter 1412593 1167135 BR1453 Brucella suis 1330 metabolite-proton symporter NP_698449.1 1411268 R 204722 CDS NP_698450.1 23502323 1167136 1412601..1412855 1 NC_004310.3 hypothetical protein 1412855 1167136 BR1454 Brucella suis 1330 hypothetical protein NP_698450.1 1412601 D 204722 CDS NP_698451.1 23502324 1167137 complement(1413029..1413796) 1 NC_004310.3 catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase 1413796 tam 1167137 tam Brucella suis 1330 trans-aconitate 2-methyltransferase NP_698451.1 1413029 R 204722 CDS NP_698452.1 23502325 1167138 complement(1413869..1415518) 1 NC_004310.3 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein 1415518 1167138 BR1456 Brucella suis 1330 ABC transporter ATP-binding protein NP_698452.1 1413869 R 204722 CDS NP_698453.1 23502326 1167139 complement(1415598..1415777) 1 NC_004310.3 hypothetical protein 1415777 1167139 BR1457 Brucella suis 1330 hypothetical protein NP_698453.1 1415598 R 204722 CDS NP_698454.1 23502327 1167140 1416014..1416958 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1266; hypothetical protein 1416958 1167140 BR1458 Brucella suis 1330 hypothetical protein NP_698454.1 1416014 D 204722 CDS NP_698455.1 23502328 1167141 1416997..1417662 1 NC_004310.3 hypothetical protein 1417662 1167141 BR1459 Brucella suis 1330 hypothetical protein NP_698455.1 1416997 D 204722 CDS NP_698456.1 23502329 1167142 complement(1417756..1418442) 1 NC_004310.3 identified by similarity to OMNI:NTL01PM1376; hypothetical protein 1418442 1167142 BR1460 Brucella suis 1330 hypothetical protein NP_698456.1 1417756 R 204722 CDS NP_698457.1 23502330 1167143 1418823..1420040 1 NC_004310.3 identified by match to protein family HMM PF00355; Rieske 2Fe-2S family protein 1420040 1167143 BR1461 Brucella suis 1330 Rieske 2Fe-2S family protein NP_698457.1 1418823 D 204722 CDS NP_698458.1 23502331 1167144 1420074..1421192 1 NC_004310.3 identified by similarity to EGAD:91746; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; NADH oxidoreductase 1421192 1167144 BR1462 Brucella suis 1330 NADH oxidoreductase NP_698458.1 1420074 D 204722 CDS NP_698459.1 23502332 1167145 complement(1421206..1421415) 1 NC_004310.3 identified by similarity to SP:P16680; match to protein family HMM PF03831; phnA protein 1421415 1167145 BR1463 Brucella suis 1330 phnA protein NP_698459.1 1421206 R 204722 CDS NP_698460.1 23502333 1167146 1421553..1422182 1 NC_004310.3 identified by similarity to SP:P21369; match to protein family HMM PF00857; pyrazinamidase/nicotinamidase 1422182 pncA 1167146 pncA Brucella suis 1330 pyrazinamidase/nicotinamidase NP_698460.1 1421553 D 204722 CDS NP_698461.1 23502334 1167147 complement(1422179..1423240) 1 NC_004310.3 identified by match to protein family HMM PF04332; hypothetical protein 1423240 1167147 BR1465 Brucella suis 1330 hypothetical protein NP_698461.1 1422179 R 204722 CDS NP_698462.1 23502335 1167148 1423587..1423853 1 NC_004310.3 hypothetical protein 1423853 1167148 BR1466 Brucella suis 1330 hypothetical protein NP_698462.1 1423587 D 204722 CDS NP_698463.1 23502336 1167149 complement(1423809..1423988) 1 NC_004310.3 hypothetical protein 1423988 1167149 BR1467 Brucella suis 1330 hypothetical protein NP_698463.1 1423809 R 204722 CDS NP_698464.1 23502337 1167150 complement(1424051..1425052) 1 NC_004310.3 identified by match to protein family HMM PF02275; choloylglycine hydrolase 1425052 1167150 BR1468 Brucella suis 1330 choloylglycine hydrolase NP_698464.1 1424051 R 204722 CDS NP_698465.1 23502338 1167151 1425430..1426233 1 NC_004310.3 identified by similarity to GP:14523684; hypothetical protein 1426233 1167151 BR1469 Brucella suis 1330 hypothetical protein NP_698465.1 1425430 D 204722 CDS NP_698466.1 23502339 1167152 1426840..1427013 1 NC_004310.3 hypothetical protein 1427013 1167152 BR1470 Brucella suis 1330 hypothetical protein NP_698466.1 1426840 D 204722 CDS NP_698467.1 23502340 1167153 complement(1427067..1427294) 1 NC_004310.3 hypothetical protein 1427294 1167153 BR1471 Brucella suis 1330 hypothetical protein NP_698467.1 1427067 R 204722 CDS NP_698468.1 23502341 1167154 1427421..1427774 1 NC_004310.3 hypothetical protein 1427774 1167154 BR1472 Brucella suis 1330 hypothetical protein NP_698468.1 1427421 D 204722 CDS NP_698469.1 23502342 1167155 complement(1427935..1428507) 1 NC_004310.3 hypothetical protein 1428507 1167155 BR1473 Brucella suis 1330 hypothetical protein NP_698469.1 1427935 R 204722 CDS NP_698470.1 23502343 1167156 1428743..1429237 1 NC_004310.3 identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1429237 1167156 BR1474 Brucella suis 1330 phage integrase site specific recombinase NP_698470.1 1428743 D 204722 CDS NP_698471.1 23502344 1167158 1429655..1430407 1 NC_004310.3 identified by similarity to EGAD:40996; match to protein family HMM PF04402; hypothetical protein 1430407 omp28 1167158 omp28 Brucella suis 1330 hypothetical protein NP_698471.1 1429655 D 204722 CDS NP_698472.1 23502345 1167159 complement(1430582..1430926) 1 NC_004310.3 hypothetical protein 1430926 1167159 BR1476 Brucella suis 1330 hypothetical protein NP_698472.1 1430582 R 204722 CDS NP_698473.1 23502346 1167160 complement(1431170..1431628) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1869; match to protein family HMM PF05779; hypothetical protein 1431628 1167160 BR1477 Brucella suis 1330 hypothetical protein NP_698473.1 1431170 R 204722 CDS NP_698474.1 23502347 1167161 complement(1431820..1432110) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML1900; hypothetical protein 1432110 1167161 BR1478 Brucella suis 1330 hypothetical protein NP_698474.1 1431820 R 204722 CDS NP_698475.1 23502348 1167162 complement(1432134..1434152) 1 NC_004310.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 1434152 rpoD 1167162 rpoD Brucella suis 1330 RNA polymerase sigma factor RpoD NP_698475.1 1432134 R 204722 CDS NP_698476.1 23502349 1167163 complement(1434620..1436587) 1 NC_004310.3 synthesizes RNA primers at the replication forks; DNA primase 1436587 dnaG 1167163 dnaG Brucella suis 1330 DNA primase NP_698476.1 1434620 R 204722 CDS NP_698477.1 23502350 1167164 1436957..1438633 1 NC_004310.3 identified by match to protein family HMM PF02690; Na/Pi-cotransporter family protein 1438633 1167164 BR1481 Brucella suis 1330 Na/Pi-cotransporter family protein NP_698477.1 1436957 D 204722 CDS NP_698478.1 23502351 1167165 complement(1438700..1439152) 1 NC_004310.3 identified by similarity to GP:15075342; match to protein family HMM PF02637; hypothetical protein 1439152 1167165 BR1482 Brucella suis 1330 hypothetical protein NP_698478.1 1438700 R 204722 CDS NP_698479.1 23502352 1167166 1439532..1440755 1 NC_004310.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1440755 carA 1167166 carA Brucella suis 1330 carbamoyl phosphate synthase small subunit NP_698479.1 1439532 D 204722 CDS NP_698480.1 23502353 1167167 1440763..1440891 1 NC_004310.3 hypothetical protein 1440891 1167167 BR1484 Brucella suis 1330 hypothetical protein NP_698480.1 1440763 D 204722 CDS NP_698481.1 23502354 1167168 complement(1440927..1441853) 1 NC_004310.3 identified by similarity to GP:15074511; match to protein family HMM PF04228; hypothetical protein 1441853 1167168 BR1485 Brucella suis 1330 hypothetical protein NP_698481.1 1440927 R 204722 CDS NP_698482.1 23502355 1167169 complement(1441970..1442488) 1 NC_004310.3 identified by similarity to GP:15157321; hypothetical protein 1442488 1167169 BR1486 Brucella suis 1330 hypothetical protein NP_698482.1 1441970 R 204722 CDS NP_698483.1 23502356 1167170 1442502..1443374 1 NC_004310.3 identified by similarity to GP:15157322; match to protein family HMM PF04397; hypothetical protein 1443374 1167170 BR1487 Brucella suis 1330 hypothetical protein NP_698483.1 1442502 D 204722 CDS NP_698484.1 23502357 1167171 1443609..1447097 1 NC_004310.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1447097 carB 1167171 carB Brucella suis 1330 carbamoyl phosphate synthase large subunit NP_698484.1 1443609 D 204722 CDS NP_698485.1 23502358 1167172 1447418..1447756 1 NC_004310.3 hypothetical protein 1447756 1167172 BR1489 Brucella suis 1330 hypothetical protein NP_698485.1 1447418 D 204722 CDS NP_698486.1 23502359 1167173 complement(1447814..1449679) 1 NC_004310.3 identified by similarity to GP:2808503; transporter 1449679 1167173 BR1490 Brucella suis 1330 transporter NP_698486.1 1447814 R 204722 CDS NP_698487.1 23502360 1167174 1449869..1450330 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 1450330 1167174 BR1491 Brucella suis 1330 MutT/nudix family protein NP_698487.1 1449869 D 204722 CDS NP_698488.1 23502361 1167175 1450523..1450732 1 NC_004310.3 identified by similarity to SP:Q9Z3S6; match to protein family HMM PF00313; cold-shock family protein 1450732 1167175 BR1492 Brucella suis 1330 cold-shock family protein NP_698488.1 1450523 D 204722 CDS NP_698489.1 23502362 1167176 complement(1450862..1451473) 1 NC_004310.3 identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 1451473 1167176 BR1493 Brucella suis 1330 glutathione S-transferase NP_698489.1 1450862 R 204722 CDS NP_698490.1 23502363 1167177 complement(1451596..1451724) 1 NC_004310.3 hypothetical protein 1451724 1167177 BR1494 Brucella suis 1330 hypothetical protein NP_698490.1 1451596 R 204722 CDS NP_698491.1 23502364 1167178 1451723..1452925 1 NC_004310.3 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1452925 aspC 1167178 aspC Brucella suis 1330 aspartate aminotransferase NP_698491.1 1451723 D 204722 CDS NP_698492.1 23502365 1167179 1452945..1453052 1 NC_004310.3 hypothetical protein 1453052 1167179 BR1496 Brucella suis 1330 hypothetical protein NP_698492.1 1452945 D 204722 CDS NP_698493.1 23502366 1167180 1453128..1453343 1 NC_004310.3 hypothetical protein 1453343 1167180 BR1497 Brucella suis 1330 hypothetical protein NP_698493.1 1453128 D 204722 CDS NP_698494.1 23502367 1167181 complement(1453395..1454300) 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1454300 1167181 BR1498 Brucella suis 1330 LysR family transcriptional regulator NP_698494.1 1453395 R 204722 CDS NP_698495.1 23502368 1167182 complement(1454371..1455345) 1 NC_004310.3 identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM TIGR01292; thioredoxin reductase 1455345 trxB 1167182 trxB Brucella suis 1330 thioredoxin reductase NP_698495.1 1454371 R 204722 CDS NP_698496.1 23502369 1167183 1455667..1457067 1 NC_004310.3 identified by similarity to GP:3288671; match to protein family HMM PF02386; cation transport protein 1457067 1167183 BR1500 Brucella suis 1330 cation transport protein NP_698496.1 1455667 D 204722 CDS NP_698497.1 23502370 1167184 1457074..1457238 1 NC_004310.3 hypothetical protein 1457238 1167184 BR1501 Brucella suis 1330 hypothetical protein NP_698497.1 1457074 D 204722 CDS NP_698498.1 23502371 1167185 1457325..1457795 1 NC_004310.3 identified by similarity to SP:P56901; match to protein family HMM PF01037; leucine-responsive regulatory protein 1457795 lrp-1 1167185 lrp-1 Brucella suis 1330 leucine-responsive regulatory protein NP_698498.1 1457325 D 204722 CDS NP_698499.1 23502372 1167186 complement(1457802..1458866) 1 NC_004310.3 identified by similarity to SP:O68547; match to protein family HMM PF00534; lipopolysaccharide core biosynthesis mannosyltransferase LpcC 1458866 lpcC 1167186 lpcC Brucella suis 1330 lipopolysaccharide core biosynthesis mannosyltransferase LpcC NP_698499.1 1457802 R 204722 CDS NP_698500.1 23502373 1167187 complement(1458873..1459346) 1 NC_004310.3 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 1459346 greA 1167187 greA Brucella suis 1330 transcription elongation factor GreA NP_698500.1 1458873 R 204722 CDS NP_698501.1 23502374 1167188 complement(1459615..1460634) 1 NC_004310.3 identified by similarity to EGAD:91665; hypothetical protein 1460634 1167188 BR1505 Brucella suis 1330 hypothetical protein NP_698501.1 1459615 R 204722 CDS NP_698502.1 23502375 1167189 complement(1460660..1460848) 1 NC_004310.3 hypothetical protein 1460848 1167189 BR1506 Brucella suis 1330 hypothetical protein NP_698502.1 1460660 R 204722 CDS NP_698503.1 23502376 1167190 1460826..1461737 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 1461737 1167190 BR1507 Brucella suis 1330 hypothetical protein NP_698503.1 1460826 D 204722 CDS NP_698504.1 23502377 1167191 complement(1461742..1462092) 1 NC_004310.3 identified by match to protein family HMM PF04342; hypothetical protein 1462092 1167191 BR1508 Brucella suis 1330 hypothetical protein NP_698504.1 1461742 R 204722 CDS NP_698505.1 23502378 1167192 1462370..1463281 1 NC_004310.3 identified by similarity to GP:15074829; hypothetical protein 1463281 1167192 BR1509 Brucella suis 1330 hypothetical protein NP_698505.1 1462370 D 204722 CDS NP_698506.1 23502379 1167193 complement(1463414..1463803) 1 NC_004310.3 identified by match to protein family HMM PF03061; long-chain acyl-CoA thioester hydrolase 1463803 1167193 BR1510 Brucella suis 1330 long-chain acyl-CoA thioester hydrolase NP_698506.1 1463414 R 204722 CDS NP_698507.1 23502380 1167194 1464025..1464606 1 NC_004310.3 identified by similarity to GP:15162152; hypothetical protein 1464606 1167194 BR1511 Brucella suis 1330 hypothetical protein NP_698507.1 1464025 D 204722 CDS NP_698508.1 23502381 1167195 1464732..1467554 1 NC_004310.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1467554 uvrB 1167195 uvrB Brucella suis 1330 excinuclease ABC subunit B NP_698508.1 1464732 D 204722 CDS NP_698509.1 23502382 1167197 1468984..1469199 1 NC_004310.3 identified by match to protein family HMM PF00313; cold-shock family protein 1469199 1167197 BR1514 Brucella suis 1330 cold-shock family protein NP_698509.1 1468984 D 204722 CDS NP_698510.1 23502383 1167198 complement(1469437..1469556) 1 NC_004310.3 hypothetical protein 1469556 1167198 BR1515 Brucella suis 1330 hypothetical protein NP_698510.1 1469437 R 204722 CDS NP_698511.1 23502384 1167199 1469616..1470125 1 NC_004310.3 identified by similarity to GP:15075354; hypothetical protein 1470125 1167199 BR1516 Brucella suis 1330 hypothetical protein NP_698511.1 1469616 D 204722 CDS NP_698512.1 23502385 1167200 complement(1470184..1470840) 1 NC_004310.3 identified by match to protein family HMM PF00753; metallo-beta-lactamase 1470840 1167200 BR1517 Brucella suis 1330 metallo-beta-lactamase NP_698512.1 1470184 R 204722 CDS NP_698513.1 23502386 1167201 complement(1471054..1471335) 1 NC_004310.3 hypothetical protein 1471335 1167201 BR1518 Brucella suis 1330 hypothetical protein NP_698513.1 1471054 R 204722 CDS NP_698514.1 23502387 1167202 1471507..1471806 1 NC_004310.3 hypothetical protein 1471806 1167202 BR1519 Brucella suis 1330 hypothetical protein NP_698514.1 1471507 D 204722 CDS NP_698515.1 23502388 1167203 1471857..1472396 1 NC_004310.3 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1472396 1167203 BR1520 Brucella suis 1330 MarR family transcriptional regulator NP_698515.1 1471857 D 204722 CDS NP_698516.1 23502389 1167204 1472478..1473203 1 NC_004310.3 identified by similarity to EGAD:19467; match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein OmpR 1473203 1167204 BR1521 Brucella suis 1330 transcriptional regulatory protein OmpR NP_698516.1 1472478 D 204722 CDS NP_698517.1 23502390 1167205 1473392..1474690 1 NC_004310.3 identified by similarity to EGAD:163236; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; osmolarity sensor protein EnvZ 1474690 1167205 BR1522 Brucella suis 1330 osmolarity sensor protein EnvZ NP_698517.1 1473392 D 204722 CDS NP_698518.1 23502391 1167206 complement(1475022..1475141) 1 NC_004310.3 hypothetical protein 1475141 1167206 BR1523 Brucella suis 1330 hypothetical protein NP_698518.1 1475022 R 204722 CDS NP_698519.1 23502392 1167207 complement(1475122..1475469) 1 NC_004310.3 identified by similarity to SP:P37584; match to protein family HMM PF01588; csaA protein 1475469 csaA 1167207 csaA Brucella suis 1330 csaA protein NP_698519.1 1475122 R 204722 CDS NP_698520.1 23502393 1167208 complement(1475608..1476270) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2065; hypothetical protein 1476270 1167208 BR1525 Brucella suis 1330 hypothetical protein NP_698520.1 1475608 R 204722 CDS NP_698521.1 23502394 1167209 complement(1476537..1476857) 1 NC_004310.3 identified by similarity to GP:15075365; match to protein family HMM PF04380; hypothetical protein 1476857 1167209 BR1526 Brucella suis 1330 hypothetical protein NP_698521.1 1476537 R 204722 CDS NP_698522.1 23502395 1167210 complement(1476875..1477027) 1 NC_004310.3 hypothetical protein 1477027 1167210 BR1527 Brucella suis 1330 hypothetical protein NP_698522.1 1476875 R 204722 CDS NP_698523.1 23502396 1167211 1477042..1477887 1 NC_004310.3 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1477887 lgt 1167211 lgt Brucella suis 1330 prolipoprotein diacylglyceryl transferase NP_698523.1 1477042 D 204722 CDS NP_698524.1 23502397 1167212 1477880..1478977 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2069; match to protein family HMM PF02636; hypothetical protein 1478977 1167212 BR1529 Brucella suis 1330 hypothetical protein NP_698524.1 1477880 D 204722 CDS NP_698525.1 23502398 1167213 1479157..1480008 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2070; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 1480008 1167213 BR1530 Brucella suis 1330 hypothetical protein NP_698525.1 1479157 D 204722 CDS NP_698526.1 23502399 1167214 1480121..1481272 1 NC_004310.3 identified by match to protein family HMM PF00557; M24 family peptidase 1481272 1167214 BR1531 Brucella suis 1330 M24 family peptidase NP_698526.1 1480121 D 204722 CDS NP_698527.1 23502400 1167215 1481326..1481880 1 NC_004310.3 identified by similarity to GP:15075370; lipoprotein 1481880 1167215 BR1532 Brucella suis 1330 lipoprotein NP_698527.1 1481326 D 204722 CDS NP_698528.1 23502401 1167216 1482219..1483151 1 NC_004310.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1483151 prsA 1167216 prsA Brucella suis 1330 ribose-phosphate pyrophosphokinase NP_698528.1 1482219 D 204722 CDS NP_698529.1 23502402 1167217 complement(1483299..1484840) 1 NC_004310.3 identified by similarity to GP:15074722; hypothetical protein 1484840 1167217 BR1534 Brucella suis 1330 hypothetical protein NP_698529.1 1483299 R 204722 CDS NP_698530.1 23502403 1167218 1485532..1486155 1 NC_004310.3 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1486155 1167218 BR1535 Brucella suis 1330 50S ribosomal protein L25 NP_698530.1 1485532 D 204722 CDS NP_698531.1 23502404 1167219 1486184..1486936 1 NC_004310.3 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1486936 pth 1167219 pth Brucella suis 1330 peptidyl-tRNA hydrolase NP_698531.1 1486184 D 204722 CDS NP_698532.1 23502405 1167220 1487024..1488127 1 NC_004310.3 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1488127 1167220 BR1537 Brucella suis 1330 GTP-dependent nucleic acid-binding protein EngD NP_698532.1 1487024 D 204722 CDS NP_698533.1 23502406 1167221 1488189..1488689 1 NC_004310.3 identified by match to protein family HMM PF01575; acyl dehydratase MaoC 1488689 1167221 BR1538 Brucella suis 1330 acyl dehydratase MaoC NP_698533.1 1488189 D 204722 CDS NP_698534.1 23502407 1167222 1488686..1489168 1 NC_004310.3 identified by match to protein family HMM PF01575; acyl dehydratase MaoC 1489168 1167222 BR1539 Brucella suis 1330 acyl dehydratase MaoC NP_698534.1 1488686 D 204722 CDS NP_698535.1 23502408 1167223 complement(1489210..1489770) 1 NC_004310.3 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 1489770 apt 1167223 apt Brucella suis 1330 adenine phosphoribosyltransferase NP_698535.1 1489210 R 204722 CDS NP_698536.1 23502409 1167224 complement(1490078..1490965) 1 NC_004310.3 identified by match to protein family HMM PF02167; ubiquinol-cytochrome c reductase, cytochrome c1 1490965 1167224 BR1541 Brucella suis 1330 ubiquinol-cytochrome c reductase, cytochrome c1 NP_698536.1 1490078 R 204722 CDS NP_698537.1 23502410 1167225 complement(1490979..1492277) 1 NC_004310.3 identified by similarity to EGAD:46867; match to protein family HMM PF00032; match to protein family HMM PF00033; ubiquinol-cytochrome c reductase, cytochrome b 1492277 petB 1167225 petB Brucella suis 1330 ubiquinol-cytochrome c reductase, cytochrome b NP_698537.1 1490979 R 204722 CDS NP_698538.1 23502411 1167226 complement(1492299..1492862) 1 NC_004310.3 identified by similarity to EGAD:9907; match to protein family HMM PF00355; match to protein family HMM TIGR01409; match to protein family HMM TIGR01416; ubiquinol-cytochrome c reductase, iron-sulfur subunit 1492862 1167226 BR1543 Brucella suis 1330 ubiquinol-cytochrome c reductase, iron-sulfur subunit NP_698538.1 1492299 R 204722 CDS NP_698539.1 23502412 1167229 1497151..1497630 1 NC_004310.3 identified by match to protein family HMM PF00588; RNA methyltransferase 1497630 1167229 BR1546 Brucella suis 1330 RNA methyltransferase NP_698539.1 1497151 D 204722 CDS NP_698540.1 23502413 1167231 complement(1498780..1498881) 1 NC_004310.3 hypothetical protein 1498881 1167231 BR1548 Brucella suis 1330 hypothetical protein NP_698540.1 1498780 R 204722 CDS NP_698541.1 23502414 1167232 complement(1498889..1499149) 1 NC_004310.3 identified by similarity to GP:15074760; hypothetical protein 1499149 1167232 BR1549 Brucella suis 1330 hypothetical protein NP_698541.1 1498889 R 204722 CDS NP_698542.1 23502415 1167233 1499443..1500354 1 NC_004310.3 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1500354 hemF 1167233 hemF Brucella suis 1330 coproporphyrinogen III oxidase NP_698542.1 1499443 D 204722 CDS NP_698543.1 23502416 1167234 complement(1500388..1500882) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1500882 1167234 BR1551 Brucella suis 1330 acetyltransferase NP_698543.1 1500388 R 204722 CDS NP_698544.1 23502417 1167236 complement(1501915..1503186) 1 NC_004310.3 identified by match to protein family HMM PF01743; poly(A) polymerase 1503186 1167236 BR1553 Brucella suis 1330 poly(A) polymerase NP_698544.1 1501915 R 204722 CDS NP_698545.1 23502418 1167237 complement(1503183..1503689) 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 1503689 1167237 BR1554 Brucella suis 1330 MutT/nudix family protein NP_698545.1 1503183 R 204722 CDS NP_698546.1 23502419 1167238 complement(1503803..1504468) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2109; hypothetical protein 1504468 1167238 BR1555 Brucella suis 1330 hypothetical protein NP_698546.1 1503803 R 204722 CDS NP_698547.1 23502420 1167239 1504588..1505595 1 NC_004310.3 identified by similarity to GP:2689172; moxR protein 1505595 moxR 1167239 moxR Brucella suis 1330 moxR protein NP_698547.1 1504588 D 204722 CDS NP_698548.1 23502421 1167240 1505595..1506527 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2111; match to protein family HMM PF01882; hypothetical protein 1506527 1167240 BR1557 Brucella suis 1330 hypothetical protein NP_698548.1 1505595 D 204722 CDS NP_698549.1 23502422 1167241 1506524..1509373 1 NC_004310.3 hypothetical protein 1509373 1167241 BR1558 Brucella suis 1330 hypothetical protein NP_698549.1 1506524 D 204722 CDS NP_698550.1 23502423 1167242 1509437..1511512 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2113; hypothetical protein 1511512 1167242 BR1559 Brucella suis 1330 hypothetical protein NP_698550.1 1509437 D 204722 CDS NP_698551.1 23502424 1167243 complement(1511580..1512086) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1512086 1167243 BR1560 Brucella suis 1330 acetyltransferase NP_698551.1 1511580 R 204722 CDS NP_698552.1 23502425 1167244 1512390..1513373 1 NC_004310.3 glutathione S-transferase domain-containing protein 1513373 1167244 BR1561 Brucella suis 1330 glutathione S-transferase domain-containing protein NP_698552.1 1512390 D 204722 CDS NP_698553.1 23502426 1167245 1513521..1514204 1 NC_004310.3 identified by match to protein family HMM PF03922; hypothetical protein 1514204 1167245 BR1562 Brucella suis 1330 hypothetical protein NP_698553.1 1513521 D 204722 CDS NP_698554.1 23502427 1167246 complement(1514238..1514693) 1 NC_004310.3 identified by match to protein family HMM PF00293; MutT/nudix family protein 1514693 1167246 BR1563 Brucella suis 1330 MutT/nudix family protein NP_698554.1 1514238 R 204722 CDS NP_698555.1 23502428 1167247 1514802..1515704 1 NC_004310.3 identified by similarity to GP:14023230; match to protein family HMM PF00149; hypothetical protein 1515704 1167247 BR1564 Brucella suis 1330 hypothetical protein NP_698555.1 1514802 D 204722 CDS NP_698556.1 23502429 1167248 complement(1515698..1515826) 1 NC_004310.3 hypothetical protein 1515826 1167248 BR1565 Brucella suis 1330 hypothetical protein NP_698556.1 1515698 R 204722 CDS NP_698557.2 161486694 1167249 complement(1515905..1517572) 1 NC_004310.3 identified by match to protein family HMM PF00682; match to protein family HMM TIGR00970; 2-isopropylmalate synthase 1517572 leuA 1167249 leuA Brucella suis 1330 2-isopropylmalate synthase NP_698557.2 1515905 R 204722 CDS NP_698558.1 23502431 1167250 complement(1517764..1517922) 1 NC_004310.3 hypothetical protein 1517922 1167250 BR1567 Brucella suis 1330 hypothetical protein NP_698558.1 1517764 R 204722 CDS NP_698559.1 23502432 1167251 complement(1517937..1518845) 1 NC_004310.3 identified by similarity to GP:14023215; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein 1518845 1167251 BR1568 Brucella suis 1330 cation efflux family protein NP_698559.1 1517937 R 204722 CDS NP_698560.1 23502433 1167252 1518855..1519136 1 NC_004310.3 hypothetical protein 1519136 1167252 BR1569 Brucella suis 1330 hypothetical protein NP_698560.1 1518855 D 204722 CDS NP_698561.1 23502434 1167253 complement(1519315..1521510) 1 NC_004310.3 trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase 1521510 trpE 1167253 trpE Brucella suis 1330 anthranilate synthase NP_698561.1 1519315 R 204722 CDS NP_698562.1 23502435 1167254 1522189..1522650 1 NC_004310.3 identified by similarity to SP:P19494; match to protein family HMM PF01037; leucine-responsive regulatory protein 1522650 lrp-2 1167254 lrp-2 Brucella suis 1330 leucine-responsive regulatory protein NP_698562.1 1522189 D 204722 CDS NP_698563.1 23502436 1167255 1522791..1523201 1 NC_004310.3 identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1523201 1167255 BR1572 Brucella suis 1330 MarR family transcriptional regulator NP_698563.1 1522791 D 204722 CDS NP_698564.1 23502437 1167256 1523296..1524588 1 NC_004310.3 identified by similarity to GP:17430574; transporter 1524588 1167256 BR1573 Brucella suis 1330 transporter NP_698564.1 1523296 D 204722 CDS NP_698565.1 23502438 1167257 complement(1524583..1525548) 1 NC_004310.3 identified by similarity to GP:14027266; hypothetical protein 1525548 1167257 BR1574 Brucella suis 1330 hypothetical protein NP_698565.1 1524583 R 204722 CDS NP_698566.1 23502439 1167258 complement(1525554..1526750) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2131; hypothetical protein 1526750 1167258 BR1575 Brucella suis 1330 hypothetical protein NP_698566.1 1525554 R 204722 CDS NP_698567.1 23502440 1167259 complement(1526747..1526896) 1 NC_004310.3 hypothetical protein 1526896 1167259 BR1576 Brucella suis 1330 hypothetical protein NP_698567.1 1526747 R 204722 CDS NP_698568.1 23502441 1167260 complement(1526880..1527005) 1 NC_004310.3 hypothetical protein 1527005 1167260 BR1577 Brucella suis 1330 hypothetical protein NP_698568.1 1526880 R 204722 CDS NP_698569.1 23502442 1167261 1526982..1527101 1 NC_004310.3 hypothetical protein 1527101 1167261 BR1578 Brucella suis 1330 hypothetical protein NP_698569.1 1526982 D 204722 CDS NP_698570.1 23502443 1167262 1527186..1528154 1 NC_004310.3 identified by similarity to GP:19880073; match to protein family HMM PF04069; glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein 1528154 1167262 BR1579 Brucella suis 1330 glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein NP_698570.1 1527186 D 204722 CDS NP_698571.1 23502444 1167263 1528243..1529079 1 NC_004310.3 identified by similarity to GP:17982347; match to protein family HMM PF00528; glycine betaine/L-proline ABC transporter permease 1529079 1167263 BR1580 Brucella suis 1330 glycine betaine/L-proline ABC transporter permease NP_698571.1 1528243 D 204722 CDS NP_698572.1 23502445 1167264 1529249..1530295 1 NC_004310.3 identified by similarity to SP:P46920; match to protein family HMM PF00005; glycine betaine/L-proline ABC transporter ATP-binding protein 1530295 1167264 BR1581 Brucella suis 1330 glycine betaine/L-proline ABC transporter ATP-binding protein NP_698572.1 1529249 D 204722 CDS NP_698573.1 23502446 1167265 complement(1530569..1531417) 1 NC_004310.3 identified by similarity to SP:P37313; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein 1531417 1167265 BR1582 Brucella suis 1330 dipeptide ABC transporter ATP-binding protein NP_698573.1 1530569 R 204722 CDS NP_698574.1 23502447 1167266 complement(1531414..1532262) 1 NC_004310.3 identified by similarity to SP:P37314; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein 1532262 1167266 BR1583 Brucella suis 1330 dipeptide ABC transporter ATP-binding protein NP_698574.1 1531414 R 204722 CDS NP_698575.1 23502448 1167267 complement(1532268..1533149) 1 NC_004310.3 identified by similarity to SP:P94312; match to protein family HMM PF00528; dipeptide ABC transporter permease 1533149 1167267 BR1584 Brucella suis 1330 dipeptide ABC transporter permease NP_698575.1 1532268 R 204722 CDS NP_698576.1 23502449 1167268 complement(1533157..1534164) 1 NC_004310.3 identified by similarity to SP:P94311; match to protein family HMM PF00528; dipeptide ABC transporter permease 1534164 1167268 BR1585 Brucella suis 1330 dipeptide ABC transporter permease NP_698576.1 1533157 R 204722 CDS NP_698577.1 23502450 1167270 1536202..1536507 1 NC_004310.3 hypothetical protein 1536507 1167270 BR1587 Brucella suis 1330 hypothetical protein NP_698577.1 1536202 D 204722 CDS NP_698578.1 23502451 1167271 complement(1536748..1536975) 1 NC_004310.3 hypothetical protein 1536975 1167271 BR1588 Brucella suis 1330 hypothetical protein NP_698578.1 1536748 R 204722 CDS NP_698579.1 23502452 1167272 1536965..1537312 1 NC_004310.3 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1537312 1167272 BR1589 Brucella suis 1330 ArsR family transcriptional regulator NP_698579.1 1536965 D 204722 CDS NP_698580.1 23502453 1167273 1537342..1538172 1 NC_004310.3 identified by match to protein family HMM PF00588; RNA methyltransferase 1538172 1167273 BR1590 Brucella suis 1330 RNA methyltransferase NP_698580.1 1537342 D 204722 CDS NP_698581.1 23502454 1167274 complement(1538394..1539590) 1 NC_004310.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 1539590 mnmA 1167274 mnmA Brucella suis 1330 tRNA-specific 2-thiouridylase MnmA NP_698581.1 1538394 R 204722 CDS NP_698582.1 23502455 1167275 complement(1539628..1539786) 1 NC_004310.3 hypothetical protein 1539786 1167275 BR1592 Brucella suis 1330 hypothetical protein NP_698582.1 1539628 R 204722 CDS NP_698583.1 23502456 1167276 1539895..1540170 1 NC_004310.3 identified by similarity to GP:15075739; hypothetical protein 1540170 1167276 BR1593 Brucella suis 1330 hypothetical protein NP_698583.1 1539895 D 204722 CDS NP_698584.1 23502457 1167277 1540373..1540666 1 NC_004310.3 identified by similarity to GP:15075740; hypothetical protein 1540666 1167277 BR1594 Brucella suis 1330 hypothetical protein NP_698584.1 1540373 D 204722 CDS NP_698585.1 23502458 1167278 complement(1540714..1541649) 1 NC_004310.3 identified by similarity to GP:14023239; hypothetical protein 1541649 1167278 BR1595 Brucella suis 1330 hypothetical protein NP_698585.1 1540714 R 204722 CDS NP_698586.1 23502459 1167279 complement(1541879..1542475) 1 NC_004310.3 identified by similarity to GP:17740928; hypothetical protein 1542475 1167279 BR1596 Brucella suis 1330 hypothetical protein NP_698586.1 1541879 R 204722 CDS NP_698587.1 23502460 1167280 complement(1542745..1542888) 1 NC_004310.3 hypothetical protein 1542888 1167280 BR1597 Brucella suis 1330 hypothetical protein NP_698587.1 1542745 R 204722 CDS NP_698588.1 23502461 1167281 1542887..1543516 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2168; hypothetical protein 1543516 1167281 BR1598 Brucella suis 1330 hypothetical protein NP_698588.1 1542887 D 204722 CDS NP_698589.1 23502462 1167282 complement(1543629..1544327) 1 NC_004310.3 identified by similarity to EGAD:41053; match to protein family HMM PF00072; match to protein family HMM PF00486; cell cycle transcriptional regulator CtrA 1544327 ctrA 1167282 ctrA Brucella suis 1330 cell cycle transcriptional regulator CtrA NP_698589.1 1543629 R 204722 CDS NP_698590.1 23502463 1167283 1544858..1545250 1 NC_004310.3 identified by similarity to GP:15075741; hypothetical protein 1545250 1167283 BR1600 Brucella suis 1330 hypothetical protein NP_698590.1 1544858 D 204722 CDS NP_698591.1 23502464 1167284 complement(1545334..1546458) 1 NC_004310.3 identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family protein 1546458 1167284 BR1601 Brucella suis 1330 DegT/DnrJ/EryC1/StrS family protein NP_698591.1 1545334 R 204722 CDS NP_698592.1 23502465 1167285 complement(1546618..1547574) 1 NC_004310.3 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 1547574 1167285 BR1602 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_698592.1 1546618 R 204722 CDS NP_698593.1 23502466 1167286 complement(1547580..1547705) 1 NC_004310.3 hypothetical protein 1547705 1167286 BR1603 Brucella suis 1330 hypothetical protein NP_698593.1 1547580 R 204722 CDS NP_698594.1 23502467 1167288 1547976..1548230 1 NC_004310.3 hypothetical protein 1548230 1167288 BR1604 Brucella suis 1330 hypothetical protein NP_698594.1 1547976 D 204722 CDS NP_698595.1 23502468 1167289 complement(1548406..1549188) 1 NC_004310.3 identified by match to protein family HMM PF01755; glycosyl transferase 1549188 1167289 BR1605 Brucella suis 1330 glycosyl transferase NP_698595.1 1548406 R 204722 CDS NP_698596.1 23502469 1167291 1549933..1553040 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 1553040 1167291 BR1606 Brucella suis 1330 sensory box histidine kinase NP_698596.1 1549933 D 204722 CDS NP_698597.1 23502470 1167292 complement(1553260..1553391) 1 NC_004310.3 hypothetical protein 1553391 1167292 BR1607 Brucella suis 1330 hypothetical protein NP_698597.1 1553260 R 204722 CDS NP_698598.1 23502471 1167293 1553781..1555718 1 NC_004310.3 identified by similarity to EGAD:20142; match to protein family HMM PF05170; AsmA family protein 1555718 1167293 BR1608 Brucella suis 1330 AsmA family protein NP_698598.1 1553781 D 204722 CDS NP_698599.1 23502472 1167294 complement(1555726..1556547) 1 NC_004310.3 identified by similarity to GP:16502083; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1556547 1167294 BR1609 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_698599.1 1555726 R 204722 CDS NP_698600.1 23502473 1167295 complement(1556549..1557460) 1 NC_004310.3 identified by similarity to SP:P23860; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease 1557460 1167295 BR1610 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_698600.1 1556549 R 204722 CDS NP_698601.1 23502474 1167296 complement(1557476..1558621) 1 NC_004310.3 identified by similarity to SP:P31134; match to protein family HMM PF00005; match to protein family HMM TIGR01187; spermidine/putrescine ABC transporter ATP-binding protein 1558621 1167296 BR1611 Brucella suis 1330 spermidine/putrescine ABC transporter ATP-binding protein NP_698601.1 1557476 R 204722 CDS NP_698602.1 23502475 1167297 complement(1558863..1559966) 1 NC_004310.3 identified by similarity to GP:15979381; match to protein family HMM PF01547; spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein 1559966 1167297 BR1612 Brucella suis 1330 spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein NP_698602.1 1558863 R 204722 CDS NP_698603.1 23502476 1167298 complement(1560188..1561600) 1 NC_004310.3 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1561600 1167298 BR1613 Brucella suis 1330 Cro/CI family transcriptional regulator NP_698603.1 1560188 R 204722 CDS NP_698604.1 23502477 1167299 1561849..1563138 1 NC_004310.3 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 1563138 aceA 1167299 aceA Brucella suis 1330 isocitrate lyase NP_698604.1 1561849 D 204722 CDS NP_698605.1 23502478 1167300 1563173..1563409 1 NC_004310.3 identified by similarity to OMNI:NTL02ML5126; hypothetical protein 1563409 1167300 BR1615 Brucella suis 1330 hypothetical protein NP_698605.1 1563173 D 204722 CDS NP_698606.1 23502479 1167301 1563406..1563534 1 NC_004310.3 hypothetical protein 1563534 1167301 BR1616 Brucella suis 1330 hypothetical protein NP_698606.1 1563406 D 204722 CDS NP_698607.1 23502480 1167302 complement(1563518..1563673) 1 NC_004310.3 hypothetical protein 1563673 1167302 BR1617 Brucella suis 1330 hypothetical protein NP_698607.1 1563518 R 204722 CDS NP_698608.1 23502481 1167304 1564371..1565138 1 NC_004310.3 Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1565138 1167304 BR1618 Brucella suis 1330 7-alpha-hydroxysteroid dehydrogenase NP_698608.1 1564371 D 204722 CDS NP_698609.1 23502482 1167305 1565204..1565998 1 NC_004310.3 identified by similarity to EGAD:23950; match to protein family HMM PF00106; 7-alpha-hydroxysteroid dehydrogenase 1565998 1167305 BR1619 Brucella suis 1330 7-alpha-hydroxysteroid dehydrogenase NP_698609.1 1565204 D 204722 CDS NP_698610.1 23502483 1167306 1566008..1567765 1 NC_004310.3 hypothetical protein 1567765 1167306 BR1620 Brucella suis 1330 hypothetical protein NP_698610.1 1566008 D 204722 CDS NP_698611.1 23502484 1167307 1567793..1568395 1 NC_004310.3 identified by similarity to EGAD:10584; match to protein family HMM PF01914; hypothetical protein 1568395 1167307 BR1621 Brucella suis 1330 hypothetical protein NP_698611.1 1567793 D 204722 CDS NP_698612.1 23502485 1167308 1568674..1569459 1 NC_004310.3 identified by similarity to EGAD:150060; match to protein family HMM PF01389; hypothetical protein 1569459 omp31-1 1167308 omp31-1 Brucella suis 1330 hypothetical protein NP_698612.1 1568674 D 204722 CDS NP_698613.1 23502486 1167309 complement(1569596..1571146) 1 NC_004310.3 hypothetical protein 1571146 1167309 BR1623 Brucella suis 1330 hypothetical protein NP_698613.1 1569596 R 204722 CDS NP_698615.1 23502488 1167311 complement(1571447..1571548) 1 NC_004310.3 hypothetical protein 1571548 1167311 BR1625 Brucella suis 1330 hypothetical protein NP_698615.1 1571447 R 204722 CDS NP_698616.1 23502489 1167312 1571699..1571980 1 NC_004310.3 hypothetical protein 1571980 1167312 BR1626 Brucella suis 1330 hypothetical protein NP_698616.1 1571699 D 204722 CDS NP_698617.1 23502490 1167315 complement(1576891..1577664) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase 1577664 1167315 BR1629 Brucella suis 1330 short chain dehydrogenase NP_698617.1 1576891 R 204722 CDS NP_698618.1 23502491 1167316 complement(1577753..1578742) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML0801; match to protein family HMM PF00532; LacI family sugar-binding transcriptional regulator 1578742 1167316 BR1630 Brucella suis 1330 LacI family sugar-binding transcriptional regulator NP_698618.1 1577753 R 204722 CDS NP_698619.1 23502492 1167317 complement(1578918..1579922) 1 NC_004310.3 identified by similarity to SP:P04984; match to protein family HMM PF02653; ribose ABC transporter permease 1579922 rbsC-2 1167317 rbsC-2 Brucella suis 1330 ribose ABC transporter permease NP_698619.1 1578918 R 204722 CDS NP_698620.1 23502493 1167318 complement(1580018..1581478) 1 NC_004310.3 identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein 1581478 rbsA-2 1167318 rbsA-2 Brucella suis 1330 ribose ABC transporter ATP-binding protein NP_698620.1 1580018 R 204722 CDS NP_698621.1 23502494 1167319 1581658..1581795 1 NC_004310.3 hypothetical protein 1581795 1167319 BR1633 Brucella suis 1330 hypothetical protein NP_698621.1 1581658 D 204722 CDS NP_698622.1 23502495 1167320 1581792..1582109 1 NC_004310.3 hypothetical protein 1582109 1167320 BR1634 Brucella suis 1330 hypothetical protein NP_698622.1 1581792 D 204722 CDS NP_698623.1 23502496 1167321 complement(1582239..1582367) 1 NC_004310.3 hypothetical protein 1582367 1167321 BR1635 Brucella suis 1330 hypothetical protein NP_698623.1 1582239 R 204722 CDS NP_698624.1 23502497 1167325 1584775..1584927 1 NC_004310.3 hypothetical protein 1584927 1167325 BR1637 Brucella suis 1330 hypothetical protein NP_698624.1 1584775 D 204722 CDS NP_698625.1 23502498 1167327 1587882..1588124 1 NC_004310.3 hypothetical protein 1588124 1167327 BR1638 Brucella suis 1330 hypothetical protein NP_698625.1 1587882 D 204722 CDS NP_698626.1 23502499 1167331 complement(1590825..1591646) 1 NC_004310.3 identified by match to protein family HMM PF01614; IclR family transcriptional regulator 1591646 1167331 BR1639 Brucella suis 1330 IclR family transcriptional regulator NP_698626.1 1590825 R 204722 CDS NP_698627.1 23502500 1167332 1591764..1593215 1 NC_004310.3 identified by similarity to EGAD:16804; match to protein family HMM PF00171; match to protein family HMM TIGR01780; succinate-semialdehyde dehydrogenase 1593215 gabD 1167332 gabD Brucella suis 1330 succinate-semialdehyde dehydrogenase NP_698627.1 1591764 D 204722 CDS NP_698628.1 23502501 1167333 1593332..1593922 1 NC_004310.3 hypothetical protein 1593922 1167333 BR1641 Brucella suis 1330 hypothetical protein NP_698628.1 1593332 D 204722 CDS NP_698629.1 23502502 1167334 1594035..1594553 1 NC_004310.3 disulfide bond formation protein B 1594553 1167334 BR1642 Brucella suis 1330 disulfide bond formation protein B NP_698629.1 1594035 D 204722 CDS NP_698630.1 23502503 1167335 complement(1594570..1595142) 1 NC_004310.3 identified by match to protein family HMM PF01844; HNH endonuclease 1595142 1167335 BR1643 Brucella suis 1330 HNH endonuclease NP_698630.1 1594570 R 204722 CDS NP_698631.1 23502504 1167336 complement(1595139..1595231) 1 NC_004310.3 hypothetical protein 1595231 1167336 BR1644 Brucella suis 1330 hypothetical protein NP_698631.1 1595139 R 204722 CDS NP_698632.1 23502505 1167337 complement(1595293..1595400) 1 NC_004310.3 hypothetical protein 1595400 1167337 BR1645 Brucella suis 1330 hypothetical protein NP_698632.1 1595293 R 204722 CDS NP_698633.1 23502506 1167338 complement(1595416..1596114) 1 NC_004310.3 identified by match to protein family HMM PF00730; base-excision DNA repair protein 1596114 1167338 BR1646 Brucella suis 1330 base-excision DNA repair protein NP_698633.1 1595416 R 204722 CDS NP_698634.1 23502507 1167339 1596136..1597011 1 NC_004310.3 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1597011 1167339 BR1647 Brucella suis 1330 glutamyl-Q tRNA(Asp) synthetase NP_698634.1 1596136 D 204722 CDS NP_698635.1 23502508 1167340 1597154..1599340 1 NC_004310.3 catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 1599340 glcB 1167340 glcB Brucella suis 1330 malate synthase G NP_698635.1 1597154 D 204722 CDS NP_698636.1 23502509 1167341 1599645..1600139 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1600139 1167341 BR1649 Brucella suis 1330 acetyltransferase NP_698636.1 1599645 D 204722 CDS NP_698637.1 23502510 1167342 complement(1600198..1601109) 1 NC_004310.3 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 1601109 1167342 BR1650 Brucella suis 1330 RNA polymerase factor sigma-32 NP_698637.1 1600198 R 204722 CDS YP_089634.1 52430462 1167343 complement(1601540..1602583) 1 NC_004310.3 identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D 1602583 1167343 BR1651 Brucella suis 1330 ribosomal large subunit pseudouridine synthase D YP_089634.1 1601540 R 204722 CDS NP_698638.1 23502511 1167344 1602600..1603076 1 NC_004310.3 hypothetical protein 1603076 1167344 BR1652 Brucella suis 1330 hypothetical protein NP_698638.1 1602600 D 204722 CDS NP_698639.1 23502512 1167345 1603110..1603283 1 NC_004310.3 hypothetical protein 1603283 1167345 BR1653 Brucella suis 1330 hypothetical protein NP_698639.1 1603110 D 204722 CDS NP_698640.1 23502513 1167347 1603455..1603880 1 NC_004310.3 identified by similarity to SP:O30976; match to protein family HMM PF01475; ferric uptake regulation protein 1603880 1167347 BR1654 Brucella suis 1330 ferric uptake regulation protein NP_698640.1 1603455 D 204722 CDS NP_698641.1 23502514 1167348 complement(1604116..1605051) 1 NC_004310.3 sensor histidine kinase 1605051 1167348 BR1655 Brucella suis 1330 sensor histidine kinase NP_698641.1 1604116 R 204722 CDS NP_698642.1 23502515 1167349 complement(1605319..1605528) 1 NC_004310.3 hypothetical protein 1605528 1167349 BR1656 Brucella suis 1330 hypothetical protein NP_698642.1 1605319 R 204722 CDS NP_698643.1 23502516 1167350 complement(1605633..1606427) 1 NC_004310.3 in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator 1606427 1167350 BR1657 Brucella suis 1330 two-component response regulator NP_698643.1 1605633 R 204722 CDS NP_698644.1 23502517 1167351 1606874..1607446 1 NC_004310.3 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1607446 1167351 BR1658 Brucella suis 1330 RNA polymerase sigma factor NP_698644.1 1606874 D 204722 CDS NP_698645.1 23502518 1167352 1607647..1609077 1 NC_004310.3 identified by match to protein family HMM PF02518; match to protein family HMM PF05227; sensor histidine kinase 1609077 1167352 BR1659 Brucella suis 1330 sensor histidine kinase NP_698645.1 1607647 D 204722 CDS NP_698646.1 23502519 1167353 complement(1609138..1609569) 1 NC_004310.3 hypothetical protein 1609569 1167353 BR1660 Brucella suis 1330 hypothetical protein NP_698646.1 1609138 R 204722 CDS NP_698647.1 23502520 1167354 complement(1609578..1609931) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2854; hypothetical protein 1609931 1167354 BR1661 Brucella suis 1330 hypothetical protein NP_698647.1 1609578 R 204722 CDS NP_698648.1 23502521 1167355 complement(1610096..1610938) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2849; match to protein family HMM PF05239; hypothetical protein 1610938 1167355 BR1662 Brucella suis 1330 hypothetical protein NP_698648.1 1610096 R 204722 CDS NP_698649.1 23502522 1167356 complement(1610958..1611071) 1 NC_004310.3 hypothetical protein 1611071 1167356 BR1663 Brucella suis 1330 hypothetical protein NP_698649.1 1610958 R 204722 CDS NP_698650.1 23502523 1167357 complement(1611111..1611269) 1 NC_004310.3 hypothetical protein 1611269 1167357 BR1664 Brucella suis 1330 hypothetical protein NP_698650.1 1611111 R 204722 CDS NP_698651.1 23502524 1167358 1611400..1611603 1 NC_004310.3 hypothetical protein 1611603 1167358 BR1665 Brucella suis 1330 hypothetical protein NP_698651.1 1611400 D 204722 CDS NP_698652.1 23502525 1167359 1611765..1612643 1 NC_004310.3 identified by similarity to SP:P18783; match to protein family HMM PF01618; biopolymer transport protein ExbB 1612643 exbB 1167359 exbB Brucella suis 1330 biopolymer transport protein ExbB NP_698652.1 1611765 D 204722 CDS NP_698653.1 23502526 1167360 1612649..1613143 1 NC_004310.3 identified by similarity to SP:Q05606; match to protein family HMM PF02472; TonB system transport protein ExbD 1613143 1167360 BR1667 Brucella suis 1330 TonB system transport protein ExbD NP_698653.1 1612649 D 204722 CDS NP_698654.1 23502527 1167361 1613140..1614066 1 NC_004310.3 identified by match to protein family HMM TIGR01352; TonB-dependent receptor 1614066 1167361 BR1668 Brucella suis 1330 TonB-dependent receptor NP_698654.1 1613140 D 204722 CDS NP_698655.1 23502528 1167362 complement(1614109..1614879) 1 NC_004310.3 identified by similarity to GP:15074996; hypothetical protein 1614879 1167362 BR1669 Brucella suis 1330 hypothetical protein NP_698655.1 1614109 R 204722 CDS NP_698656.1 23502529 1167364 complement(1616853..1618079) 1 NC_004310.3 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein 1618079 1167364 BR1671 Brucella suis 1330 HlyD family secretion protein NP_698656.1 1616853 R 204722 CDS NP_698657.1 23502530 1167365 1618176..1618487 1 NC_004310.3 identified by similarity to EGAD:46813; IS711, transposase orfA 1618487 1167365 BR1672 Brucella suis 1330 IS711, transposase orfA NP_698657.1 1618176 D 204722 CDS NP_698658.1 23502531 1167366 1618519..1618911 1 NC_004310.3 identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 1618911 1167366 BR1673 Brucella suis 1330 IS711, transposase orfB NP_698658.1 1618519 D 204722 CDS NP_698659.1 23502532 1167367 complement(1618925..1619050) 1 NC_004310.3 hypothetical protein 1619050 1167367 BR1674 Brucella suis 1330 hypothetical protein NP_698659.1 1618925 R 204722 CDS NP_698660.1 23502533 1167368 complement(1619158..1619631) 1 NC_004310.3 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 1619631 dut 1167368 dut Brucella suis 1330 deoxyuridine 5'-triphosphate nucleotidohydrolase NP_698660.1 1619158 R 204722 CDS NP_698661.1 23502534 1167369 complement(1619855..1620325) 1 NC_004310.3 identified by match to protein family HMM PF01037; match to protein family HMM TIGR01199; AsnC family transcriptional regulator 1620325 1167369 BR1676 Brucella suis 1330 AsnC family transcriptional regulator NP_698661.1 1619855 R 204722 CDS NP_698662.1 23502535 1167370 1620471..1620686 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4136; hypothetical protein 1620686 1167370 BR1677 Brucella suis 1330 hypothetical protein NP_698662.1 1620471 D 204722 CDS NP_698663.1 23502536 1167371 1620726..1621589 1 NC_004310.3 identified by similarity to GP:13932326; match to protein family HMM PF00310; glutamine amidotransferase 1621589 1167371 BR1678 Brucella suis 1330 glutamine amidotransferase NP_698663.1 1620726 D 204722 CDS NP_698664.1 23502537 1167372 complement(1621616..1622599) 1 NC_004310.3 identified by match to protein family HMM PF01988; hypothetical protein 1622599 1167372 BR1679 Brucella suis 1330 hypothetical protein NP_698664.1 1621616 R 204722 CDS NP_698665.1 23502538 1167373 1622716..1624146 1 NC_004310.3 identified by match to protein family HMM PF00083; major facilitator family transporter 1624146 1167373 BR1680 Brucella suis 1330 major facilitator family transporter NP_698665.1 1622716 D 204722 CDS NP_698666.1 23502539 1167374 complement(1624356..1625753) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2989; hypothetical protein 1625753 1167374 BR1681 Brucella suis 1330 hypothetical protein NP_698666.1 1624356 R 204722 CDS NP_698667.1 23502540 1167375 complement(1625951..1626061) 1 NC_004310.3 hypothetical protein 1626061 1167375 BR1682 Brucella suis 1330 hypothetical protein NP_698667.1 1625951 R 204722 CDS NP_698668.1 23502541 1167376 complement(1626066..1627355) 1 NC_004310.3 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 1627355 purA 1167376 purA Brucella suis 1330 adenylosuccinate synthetase NP_698668.1 1626066 R 204722 CDS NP_698669.1 23502542 1167377 complement(1627673..1628182) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1628182 1167377 BR1684 Brucella suis 1330 acetyltransferase NP_698669.1 1627673 R 204722 CDS NP_698670.1 23502543 1167378 complement(1628187..1629788) 1 NC_004310.3 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 1629788 serA-1 1167378 serA-1 Brucella suis 1330 D-3-phosphoglycerate dehydrogenase NP_698670.1 1628187 R 204722 CDS NP_698671.1 23502544 1167379 complement(1629760..1629930) 1 NC_004310.3 hypothetical protein 1629930 1167379 BR1686 Brucella suis 1330 hypothetical protein NP_698671.1 1629760 R 204722 CDS NP_698672.1 23502545 1167380 complement(1629942..1631117) 1 NC_004310.3 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase 1631117 serC 1167380 serC Brucella suis 1330 phosphoserine aminotransferase NP_698672.1 1629942 R 204722 CDS NP_698673.1 23502546 1167381 complement(1631268..1632224) 1 NC_004310.3 identified by match to protein family HMM PF01758; sodium/bile acid transporter family protein 1632224 1167381 BR1688 Brucella suis 1330 sodium/bile acid transporter family protein NP_698673.1 1631268 R 204722 CDS NP_698674.1 23502547 1167382 complement(1632405..1633229) 1 NC_004310.3 identified by similarity to GP:17742129; outer surface protein 1633229 1167382 BR1689 Brucella suis 1330 outer surface protein NP_698674.1 1632405 R 204722 CDS NP_698675.1 23502548 1167383 complement(1633414..1634769) 1 NC_004310.3 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 1634769 glmM 1167383 glmM Brucella suis 1330 phosphoglucosamine mutase NP_698675.1 1633414 R 204722 CDS NP_698676.1 23502549 1167384 complement(1635074..1637008) 1 NC_004310.3 identified by similarity to EGAD:13183; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM TIGR01241; cell division protein FtsH 1637008 ftsH 1167384 ftsH Brucella suis 1330 cell division protein FtsH NP_698676.1 1635074 R 204722 CDS NP_698677.1 23502550 1167385 complement(1637144..1638490) 1 NC_004310.3 identified by similarity to GP:15075760; match to protein family HMM PF01171; hypothetical protein 1638490 1167385 BR1692 Brucella suis 1330 hypothetical protein NP_698677.1 1637144 R 204722 CDS NP_698678.1 23502551 1167386 complement(1638506..1639972) 1 NC_004310.3 hypothetical protein 1639972 1167386 BR1693 Brucella suis 1330 hypothetical protein NP_698678.1 1638506 R 204722 CDS NP_698679.1 23502552 1167387 complement(1640089..1640205) 1 NC_004310.3 hypothetical protein 1640205 1167387 BR1694 Brucella suis 1330 hypothetical protein NP_698679.1 1640089 R 204722 CDS NP_698680.1 23502553 1167388 complement(1640369..1640875) 1 NC_004310.3 identified by similarity to EGAD:9123; match to protein family HMM PF00691; Pal family lipoprotein 1640875 1167388 BR1695 Brucella suis 1330 Pal family lipoprotein NP_698680.1 1640369 R 204722 CDS NP_698681.1 23502554 1167389 complement(1640924..1641103) 1 NC_004310.3 hypothetical protein 1641103 1167389 BR1696 Brucella suis 1330 hypothetical protein NP_698681.1 1640924 R 204722 CDS NP_698682.1 23502555 1167390 complement(1641163..1642494) 1 NC_004310.3 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 1642494 tolB 1167390 tolB Brucella suis 1330 translocation protein TolB NP_698682.1 1641163 R 204722 CDS NP_698683.1 23502556 1167391 complement(1642550..1643620) 1 NC_004310.3 identified by similarity to GP:13898975; tolA protein 1643620 tolA 1167391 tolA Brucella suis 1330 tolA protein NP_698683.1 1642550 R 204722 CDS NP_698684.1 23502557 1167392 complement(1643628..1644080) 1 NC_004310.3 identified by match to protein family HMM PF02472; ExbD/TolR family TonB system transport protein 1644080 1167392 BR1699 Brucella suis 1330 ExbD/TolR family TonB system transport protein NP_698684.1 1643628 R 204722 CDS NP_698685.1 23502558 1167393 complement(1644127..1644837) 1 NC_004310.3 identified by match to protein family HMM PF01618; tolQ protein 1644837 tolQ 1167393 tolQ Brucella suis 1330 tolQ protein NP_698685.1 1644127 R 204722 CDS NP_698686.1 23502559 1167394 complement(1645212..1645493) 1 NC_004310.3 hypothetical protein 1645493 1167394 BR1701 Brucella suis 1330 hypothetical protein NP_698686.1 1645212 R 204722 CDS NP_698687.1 23502560 1167395 complement(1645641..1646681) 1 NC_004310.3 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 1646681 ruvB 1167395 ruvB Brucella suis 1330 Holliday junction DNA helicase RuvB NP_698687.1 1645641 R 204722 CDS NP_698688.1 23502561 1167396 complement(1646722..1647339) 1 NC_004310.3 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 1647339 ruvA 1167396 ruvA Brucella suis 1330 Holliday junction DNA helicase RuvA NP_698688.1 1646722 R 204722 CDS NP_698689.1 23502562 1167397 complement(1647344..1647865) 1 NC_004310.3 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase 1647865 ruvC 1167397 ruvC Brucella suis 1330 Holliday junction resolvase NP_698689.1 1647344 R 204722 CDS NP_698690.1 23502563 1167398 complement(1647967..1648473) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3016; hypothetical protein 1648473 1167398 BR1705 Brucella suis 1330 hypothetical protein NP_698690.1 1647967 R 204722 CDS NP_698691.1 23502564 1167399 complement(1648960..1650141) 1 NC_004310.3 identified by similarity to GP:9961345; opgC protein 1650141 1167399 BR1706 Brucella suis 1330 opgC protein NP_698691.1 1648960 R 204722 CDS NP_698692.1 23502565 1167400 1650386..1651051 1 NC_004310.3 catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1651051 1167400 BR1707 Brucella suis 1330 thiamine-phosphate pyrophosphorylase NP_698692.1 1650386 D 204722 CDS NP_698693.1 23502566 1167401 1651052..1652140 1 NC_004310.3 identified by similarity to GP:14024100; hypothetical protein 1652140 1167401 BR1708 Brucella suis 1330 hypothetical protein NP_698693.1 1651052 D 204722 CDS NP_698694.1 23502567 1167402 1652149..1652256 1 NC_004310.3 hypothetical protein 1652256 1167402 BR1709 Brucella suis 1330 hypothetical protein NP_698694.1 1652149 D 204722 CDS NP_698695.1 23502568 1167403 1652405..1652965 1 NC_004310.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1652965 efp 1167403 efp Brucella suis 1330 elongation factor P NP_698695.1 1652405 D 204722 CDS NP_698696.1 23502569 1167404 1653151..1653942 1 NC_004310.3 identified by similarity to EGAD:15335; match to protein family HMM PF00459; inositol monophosphatase 1653942 1167404 BR1711 Brucella suis 1330 inositol monophosphatase NP_698696.1 1653151 D 204722 CDS NP_698697.1 23502570 1167405 1653947..1654057 1 NC_004310.3 hypothetical protein 1654057 1167405 BR1712 Brucella suis 1330 hypothetical protein NP_698697.1 1653947 D 204722 CDS NP_698698.1 23502571 1167406 1654197..1655246 1 NC_004310.3 identified by similarity to GP:15075801; hypothetical protein 1655246 1167406 BR1713 Brucella suis 1330 hypothetical protein NP_698698.1 1654197 D 204722 CDS NP_698699.1 23502572 1167407 1655253..1656284 1 NC_004310.3 identified by match to protein family HMM PF00691; hypothetical protein 1656284 1167407 BR1714 Brucella suis 1330 hypothetical protein NP_698699.1 1655253 D 204722 CDS NP_698700.1 23502573 1167408 complement(1656318..1658117) 1 NC_004310.3 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP binding/permease 1658117 1167408 BR1715 Brucella suis 1330 ABC transporter ATP binding/permease NP_698700.1 1656318 R 204722 CDS NP_698701.1 23502574 1167409 1658433..1658654 1 NC_004310.3 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1658654 rpmE 1167409 rpmE Brucella suis 1330 50S ribosomal protein L31 NP_698701.1 1658433 D 204722 CDS NP_698702.1 23502575 1167410 complement(1658882..1659628) 1 NC_004310.3 identified by similarity to GP:15075777; match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein 1659628 1167410 BR1717 Brucella suis 1330 hypothetical protein NP_698702.1 1658882 R 204722 CDS NP_698703.1 23502576 1167412 1660704..1661279 1 NC_004310.3 identified by match to protein family HMM PF02632; BioY family protein 1661279 1167412 BR1719 Brucella suis 1330 BioY family protein NP_698703.1 1660704 D 204722 CDS NP_698704.1 23502577 1167413 1661290..1661718 1 NC_004310.3 identified by similarity to GP:14026938; hypothetical protein 1661718 1167413 BR1720 Brucella suis 1330 hypothetical protein NP_698704.1 1661290 D 204722 CDS NP_698705.1 23502578 1167414 complement(1661731..1662474) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3047; match to protein family HMM PF03741; hypothetical protein 1662474 1167414 BR1721 Brucella suis 1330 hypothetical protein NP_698705.1 1661731 R 204722 CDS NP_698706.1 23502579 1167415 complement(1662685..1663509) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3048; match to protein family HMM PF00149; match to protein family HMM TIGR00282; hypothetical protein 1663509 1167415 BR1722 Brucella suis 1330 hypothetical protein NP_698706.1 1662685 R 204722 CDS NP_698707.1 23502580 1167416 complement(1663618..1664214) 1 NC_004310.3 identified by match to protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase 1664214 1167416 BR1723 Brucella suis 1330 5-formyltetrahydrofolate cyclo-ligase NP_698707.1 1663618 R 204722 CDS NP_698708.1 23502581 1167417 complement(1664602..1664967) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2891; match to protein family HMM PF05164; hypothetical protein 1664967 1167417 BR1724 Brucella suis 1330 hypothetical protein NP_698708.1 1664602 R 204722 CDS NP_698709.1 23502582 1167418 complement(1664977..1665249) 1 NC_004310.3 hypothetical protein 1665249 1167418 BR1725 Brucella suis 1330 hypothetical protein NP_698709.1 1664977 R 204722 CDS NP_698710.1 23502583 1167419 complement(1665392..1665487) 1 NC_004310.3 hypothetical protein 1665487 1167419 BR1726 Brucella suis 1330 hypothetical protein NP_698710.1 1665392 R 204722 CDS NP_698711.1 23502584 1167420 1665666..1667657 1 NC_004310.3 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1667657 tkt 1167420 tkt Brucella suis 1330 transketolase NP_698711.1 1665666 D 204722 CDS NP_698712.1 23502585 1167421 1667798..1668805 1 NC_004310.3 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1668805 gap 1167421 gap Brucella suis 1330 glyceraldehyde-3-phosphate dehydrogenase NP_698712.1 1667798 D 204722 CDS NP_698713.1 23502586 1167422 1668876..1670063 1 NC_004310.3 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1670063 pgk 1167422 pgk Brucella suis 1330 phosphoglycerate kinase NP_698713.1 1668876 D 204722 CDS NP_698714.1 23502587 1167423 complement(1670354..1670518) 1 NC_004310.3 identified by similarity to GP:15075794; hypothetical protein 1670518 1167423 BR1730 Brucella suis 1330 hypothetical protein NP_698714.1 1670354 R 204722 CDS NP_698715.1 23502588 1167424 1670792..1672702 1 NC_004310.3 identified by match to protein family HMM PF00501; propionate--CoA ligase 1672702 prpE 1167424 prpE Brucella suis 1330 propionate--CoA ligase NP_698715.1 1670792 D 204722 CDS NP_698716.1 23502589 1167425 1672632..1672940 1 NC_004310.3 identified by similarity to GP:7206791; hypothetical protein 1672940 1167425 BR1732 Brucella suis 1330 hypothetical protein NP_698716.1 1672632 D 204722 CDS NP_698717.1 23502590 1167426 1673047..1673271 1 NC_004310.3 hypothetical protein 1673271 1167426 BR1733 Brucella suis 1330 hypothetical protein NP_698717.1 1673047 D 204722 CDS NP_698718.1 23502591 1167427 1673278..1673979 1 NC_004310.3 transcriptional regulator 1673979 1167427 BR1734 Brucella suis 1330 transcriptional regulator NP_698718.1 1673278 D 204722 CDS NP_698719.1 23502592 1167428 complement(1674232..1674339) 1 NC_004310.3 hypothetical protein 1674339 1167428 BR1735 Brucella suis 1330 hypothetical protein NP_698719.1 1674232 R 204722 CDS NP_698720.1 23502593 1167429 1674382..1674789 1 NC_004310.3 identified by similarity to OMNI:CC2103; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1674789 1167429 BR1736 Brucella suis 1330 hypothetical protein NP_698720.1 1674382 D 204722 CDS NP_698721.1 23502594 1167430 complement(1674868..1675557) 1 NC_004310.3 identified by similarity to GP:15076354; hypothetical protein 1675557 1167430 BR1737 Brucella suis 1330 hypothetical protein NP_698721.1 1674868 R 204722 CDS NP_698722.1 23502595 1167431 complement(1675685..1676665) 1 NC_004310.3 identified by match to protein family HMM PF00107; alcohol dehydrogenase 1676665 1167431 BR1738 Brucella suis 1330 alcohol dehydrogenase NP_698722.1 1675685 R 204722 CDS NP_698723.1 23502596 1167432 1676882..1677073 1 NC_004310.3 identified by similarity to GP:15075796; hypothetical protein 1677073 1167432 BR1739 Brucella suis 1330 hypothetical protein NP_698723.1 1676882 D 204722 CDS NP_698724.1 23502597 1167433 1677171..1678409 1 NC_004310.3 transporter 1678409 1167433 BR1740 Brucella suis 1330 transporter NP_698724.1 1677171 D 204722 CDS NP_698725.1 23502598 1167434 complement(1678552..1678731) 1 NC_004310.3 identified by match to protein family HMM PF04325; hypothetical protein 1678731 1167434 BR1741 Brucella suis 1330 hypothetical protein NP_698725.1 1678552 R 204722 CDS NP_698726.1 23502599 1167435 complement(1678790..1679011) 1 NC_004310.3 hypothetical protein 1679011 1167435 BR1742 Brucella suis 1330 hypothetical protein NP_698726.1 1678790 R 204722 CDS NP_698727.1 23502600 1167436 1679125..1679328 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2929; match to protein family HMM PF04325; hypothetical protein 1679328 1167436 BR1743 Brucella suis 1330 hypothetical protein NP_698727.1 1679125 D 204722 CDS NP_698728.1 23502601 1167437 1679426..1679914 1 NC_004310.3 identified by similarity to SP:P09028; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 1679914 purE 1167437 purE Brucella suis 1330 phosphoribosylaminoimidazole carboxylase, catalytic subunit NP_698728.1 1679426 D 204722 CDS NP_698729.1 23502602 1167438 1680006..1681019 1 NC_004310.3 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1681019 purK 1167438 purK Brucella suis 1330 phosphoribosylaminoimidazole carboxylase ATPase subunit NP_698729.1 1680006 D 204722 CDS NP_698730.1 23502603 1167439 1681255..1681380 1 NC_004310.3 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1681380 rpmJ 1167439 rpmJ Brucella suis 1330 50S ribosomal protein L36 NP_698730.1 1681255 D 204722 CDS NP_698731.1 23502604 1167440 1681418..1682107 1 NC_004310.3 identified by match to protein family HMM PF00515; TPR domain-containing protein 1682107 1167440 BR1747 Brucella suis 1330 TPR domain-containing protein NP_698731.1 1681418 D 204722 CDS NP_698732.1 23502605 1167441 complement(1682359..1683795) 1 NC_004310.3 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 1683795 pyk 1167441 pyk Brucella suis 1330 pyruvate kinase NP_698732.1 1682359 R 204722 CDS NP_698733.1 23502606 1167442 complement(1683792..1684253) 1 NC_004310.3 hypothetical protein 1684253 1167442 BR1749 Brucella suis 1330 hypothetical protein NP_698733.1 1683792 R 204722 CDS NP_698734.1 23502607 1167443 1684494..1685312 1 NC_004310.3 identified by match to protein family HMM PF05013; hypothetical protein 1685312 1167443 BR1750 Brucella suis 1330 hypothetical protein NP_698734.1 1684494 D 204722 CDS NP_698735.1 23502608 1167444 1685309..1685470 1 NC_004310.3 hypothetical protein 1685470 1167444 BR1751 Brucella suis 1330 hypothetical protein NP_698735.1 1685309 D 204722 CDS NP_698736.1 23502609 1167445 1685485..1685745 1 NC_004310.3 hypothetical protein 1685745 1167445 BR1752 Brucella suis 1330 hypothetical protein NP_698736.1 1685485 D 204722 CDS NP_698737.1 23502610 1167446 complement(1685837..1687654) 1 NC_004310.3 identified by similarity to GP:15157929; match to protein family HMM PF00005; ABC transporter ATP-binding protein 1687654 1167446 BR1753 Brucella suis 1330 ABC transporter ATP-binding protein NP_698737.1 1685837 R 204722 CDS NP_698738.1 23502611 1167447 complement(1687663..1687833) 1 NC_004310.3 hypothetical protein 1687833 1167447 BR1754 Brucella suis 1330 hypothetical protein NP_698738.1 1687663 R 204722 CDS NP_698739.1 23502612 1167448 complement(1687802..1688086) 1 NC_004310.3 lipoprotein 1688086 1167448 BR1755 Brucella suis 1330 lipoprotein NP_698739.1 1687802 R 204722 CDS NP_698740.1 23502613 1167449 complement(1688220..1688876) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2986; match to protein family HMM PF04263; hypothetical protein 1688876 1167449 BR1756 Brucella suis 1330 hypothetical protein NP_698740.1 1688220 R 204722 CDS NP_698741.1 23502614 1167450 1689183..1690187 1 NC_004310.3 part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 1690187 tbpA 1167450 tbpA Brucella suis 1330 thiamine transporter substrate binding subunit NP_698741.1 1689183 D 204722 CDS NP_698742.1 23502615 1167451 1690184..1691815 1 NC_004310.3 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1691815 thiP 1167451 thiP Brucella suis 1330 thiamine transporter membrane protein NP_698742.1 1690184 D 204722 CDS NP_698743.1 23502616 1167452 1691812..1692537 1 NC_004310.3 identified by match to protein family HMM PF00005; match to protein family HMM TIGR01277; thiamine ABC transporter ATP-binding protein 1692537 1167452 BR1759 Brucella suis 1330 thiamine ABC transporter ATP-binding protein NP_698743.1 1691812 D 204722 CDS NP_698744.1 23502617 1167453 complement(1692534..1692629) 1 NC_004310.3 hypothetical protein 1692629 1167453 BR1760 Brucella suis 1330 hypothetical protein NP_698744.1 1692534 R 204722 CDS NP_698745.1 23502618 1167454 1692804..1694285 1 NC_004310.3 identified by match to protein family HMM PF01435; peptidase 1694285 1167454 BR1761 Brucella suis 1330 peptidase NP_698745.1 1692804 D 204722 CDS NP_698746.1 23502619 1167455 1694312..1695040 1 NC_004310.3 identified by similarity to OMNI:NTL03PA02229; match to protein family HMM PF03473; MOSC domain-containing protein 1695040 1167455 BR1762 Brucella suis 1330 MOSC domain-containing protein NP_698746.1 1694312 D 204722 CDS NP_698747.1 23502620 1167456 complement(1695128..1696063) 1 NC_004310.3 binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 1696063 rpoH2 1167456 rpoH2 Brucella suis 1330 RNA polymerase factor sigma-32 NP_698747.1 1695128 R 204722 CDS NP_698748.1 23502621 1167457 1696104..1696307 1 NC_004310.3 hypothetical protein 1696307 1167457 BR1764 Brucella suis 1330 hypothetical protein NP_698748.1 1696104 D 204722 CDS NP_698749.1 23502622 1167458 complement(1696227..1696436) 1 NC_004310.3 hypothetical protein 1696436 1167458 BR1765 Brucella suis 1330 hypothetical protein NP_698749.1 1696227 R 204722 CDS NP_698750.1 23502623 1167459 complement(1696408..1696983) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2976; match to protein family HMM PF02559; transcriptional regulator 1696983 1167459 BR1766 Brucella suis 1330 transcriptional regulator NP_698750.1 1696408 R 204722 CDS NP_698751.1 23502624 1167460 complement(1697501..1697839) 1 NC_004310.3 identified by similarity to EGAD:22805; match to protein family HMM PF00037; ferredoxin A 1697839 fdxA 1167460 fdxA Brucella suis 1330 ferredoxin A NP_698751.1 1697501 R 204722 CDS NP_698752.1 23502625 1167461 complement(1697972..1698205) 1 NC_004310.3 hypothetical protein 1698205 1167461 BR1768 Brucella suis 1330 hypothetical protein NP_698752.1 1697972 R 204722 CDS NP_698753.1 23502626 1167462 complement(1698202..1698615) 1 NC_004310.3 identified by match to protein family HMM PF01479; S4 domain-containing protein 1698615 1167462 BR1769 Brucella suis 1330 S4 domain-containing protein NP_698753.1 1698202 R 204722 CDS NP_698754.1 23502627 1167464 complement(1702095..1702415) 1 NC_004310.3 hypothetical protein 1702415 1167464 BR1771 Brucella suis 1330 hypothetical protein NP_698754.1 1702095 R 204722 CDS NP_698755.1 23502628 1167465 complement(1702399..1703583) 1 NC_004310.3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase 1703583 phbA-1 1167465 phbA-1 Brucella suis 1330 acetyl-CoA acetyltransferase NP_698755.1 1702399 R 204722 CDS NP_698756.1 23502629 1167466 1703564..1703728 1 NC_004310.3 hypothetical protein 1703728 1167466 BR1773 Brucella suis 1330 hypothetical protein NP_698756.1 1703564 D 204722 CDS NP_698757.1 23502630 1167467 1703759..1704190 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2916; match to protein family HMM PF03928; hypothetical protein 1704190 1167467 BR1774 Brucella suis 1330 hypothetical protein NP_698757.1 1703759 D 204722 CDS NP_698758.1 23502631 1167468 complement(1704322..1704501) 1 NC_004310.3 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1704501 rpmF 1167468 rpmF Brucella suis 1330 50S ribosomal protein L32 NP_698758.1 1704322 R 204722 CDS NP_698759.1 23502632 1167469 complement(1704662..1705396) 1 NC_004310.3 glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase 1705396 mtgA 1167469 mtgA Brucella suis 1330 monofunctional biosynthetic peptidoglycan transglycosylase NP_698759.1 1704662 R 204722 CDS NP_698760.1 23502633 1167470 1705583..1706497 1 NC_004310.3 identified by similarity to SP:Q08291; match to protein family HMM PF00348; geranyltranstransferase 1706497 ispA 1167470 ispA Brucella suis 1330 geranyltranstransferase NP_698760.1 1705583 D 204722 CDS NP_698761.1 23502634 1167471 complement(1706505..1707767) 1 NC_004310.3 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 1707767 ispG 1167471 ispG Brucella suis 1330 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_698761.1 1706505 R 204722 CDS NP_698762.1 23502635 1167472 1707935..1708726 1 NC_004310.3 identified by similarity to SP:O86034; match to protein family HMM PF00106; match to protein family HMM TIGR01963; D-beta-hydroxybutyrate dehydrogenase 1708726 1167472 BR1779 Brucella suis 1330 D-beta-hydroxybutyrate dehydrogenase NP_698762.1 1707935 D 204722 CDS NP_698763.1 23502636 1167474 complement(1710000..1713476) 1 NC_004310.3 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1713476 pyc 1167474 pyc Brucella suis 1330 pyruvate carboxylase NP_698763.1 1710000 R 204722 CDS NP_698764.1 23502637 1167475 complement(1713742..1714857) 1 NC_004310.3 identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1714857 1167475 BR1782 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_698764.1 1713742 R 204722 CDS NP_698765.1 23502638 1167476 complement(1715000..1715131) 1 NC_004310.3 hypothetical protein 1715131 1167476 BR1783 Brucella suis 1330 hypothetical protein NP_698765.1 1715000 R 204722 CDS NP_698766.1 23502639 1167477 1715135..1715287 1 NC_004310.3 hypothetical protein 1715287 1167477 BR1784 Brucella suis 1330 hypothetical protein NP_698766.1 1715135 D 204722 CDS NP_698767.1 23502640 1167478 complement(1715478..1716593) 1 NC_004310.3 identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1716593 1167478 BR1785 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_698767.1 1715478 R 204722 CDS NP_698768.1 23502641 1167479 1716612..1716743 1 NC_004310.3 hypothetical protein 1716743 1167479 BR1786 Brucella suis 1330 hypothetical protein NP_698768.1 1716612 D 204722 CDS NP_698769.1 23502642 1167480 complement(1716745..1717089) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3062; hypothetical protein 1717089 1167480 BR1787 Brucella suis 1330 hypothetical protein NP_698769.1 1716745 R 204722 CDS NP_698770.1 23502643 1167482 complement(1717843..1719165) 1 NC_004310.3 identified by match to protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein 1719165 1167482 BR1789 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_698770.1 1717843 R 204722 CDS NP_698771.1 23502644 1167483 complement(1719183..1720562) 1 NC_004310.3 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1720562 1167483 BR1790 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_698771.1 1719183 R 204722 CDS NP_698772.1 23502645 1167484 complement(1720565..1721473) 1 NC_004310.3 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1721473 1167484 BR1791 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_698772.1 1720565 R 204722 CDS NP_698773.1 23502646 1167485 complement(1721767..1722768) 1 NC_004310.3 identified by similarity to GP:9695312; match to protein family HMM PF05544; hydroxyproline-2-epimerase 1722768 1167485 BR1792 Brucella suis 1330 hydroxyproline-2-epimerase NP_698773.1 1721767 R 204722 CDS NP_698774.1 23502647 1167487 1724059..1724259 1 NC_004310.3 hypothetical protein 1724259 1167487 BR1794 Brucella suis 1330 hypothetical protein NP_698774.1 1724059 D 204722 CDS NP_698775.1 23502648 1167488 1724315..1725010 1 NC_004310.3 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1725010 1167488 BR1795 Brucella suis 1330 GntR family transcriptional regulator NP_698775.1 1724315 D 204722 CDS NP_698776.1 23502649 1167489 complement(1725083..1725658) 1 NC_004310.3 identified by similarity to EGAD:16739; match to protein family HMM PF01047; MarR family transcriptional regulator 1725658 1167489 BR1796 Brucella suis 1330 MarR family transcriptional regulator NP_698776.1 1725083 R 204722 CDS NP_698777.1 23502650 1167490 complement(1725681..1725782) 1 NC_004310.3 hypothetical protein 1725782 1167490 BR1797 Brucella suis 1330 hypothetical protein NP_698777.1 1725681 R 204722 CDS NP_698778.1 23502651 1167491 complement(1725863..1726270) 1 NC_004310.3 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 1726270 atpC 1167491 atpC Brucella suis 1330 ATP synthase F0F1 subunit epsilon NP_698778.1 1725863 R 204722 CDS NP_698779.1 23502652 1167492 complement(1726395..1727960) 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 1727960 atpD 1167492 atpD Brucella suis 1330 ATP synthase F0F1 subunit beta NP_698779.1 1726395 R 204722 CDS NP_698780.1 23502653 1167493 complement(1728088..1728966) 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 1728966 atpG 1167493 atpG Brucella suis 1330 ATP synthase F0F1 subunit gamma NP_698780.1 1728088 R 204722 CDS NP_698781.1 23502654 1167494 complement(1728988..1730517) 1 NC_004310.3 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 1730517 atpA 1167494 atpA Brucella suis 1330 ATP synthase F0F1 subunit alpha NP_698781.1 1728988 R 204722 CDS NP_698782.1 23502655 1167495 complement(1730517..1731077) 1 NC_004310.3 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 1731077 atpH 1167495 atpH Brucella suis 1330 ATP synthase F0F1 subunit delta NP_698782.1 1730517 R 204722 CDS NP_698783.1 23502656 1167496 complement(1731359..1731772) 1 NC_004310.3 identified by similarity to GP:15076063; hypothetical protein 1731772 1167496 BR1803 Brucella suis 1330 hypothetical protein NP_698783.1 1731359 R 204722 CDS NP_698784.1 23502657 1167497 complement(1731839..1734073) 1 NC_004310.3 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA 1734073 priA 1167497 priA Brucella suis 1330 primosome assembly protein PriA NP_698784.1 1731839 R 204722 CDS NP_698785.1 23502658 1167498 1734183..1734836 1 NC_004310.3 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1734836 1167498 BR1805 Brucella suis 1330 translaldolase NP_698785.1 1734183 D 204722 CDS NP_698786.1 23502659 1167499 complement(1734980..1735561) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3139; hypothetical protein 1735561 1167499 BR1806 Brucella suis 1330 hypothetical protein NP_698786.1 1734980 R 204722 CDS NP_698787.1 23502660 1167500 complement(1735548..1738181) 1 NC_004310.3 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 1738181 leuS 1167500 leuS Brucella suis 1330 leucyl-tRNA synthetase NP_698787.1 1735548 R 204722 CDS NP_698788.1 23502661 1167501 1738304..1738984 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3141; match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 1738984 1167501 BR1808 Brucella suis 1330 hypothetical protein NP_698788.1 1738304 D 204722 CDS NP_698789.1 23502662 1167502 complement(1738997..1739527) 1 NC_004310.3 hypothetical protein 1739527 1167502 BR1809 Brucella suis 1330 hypothetical protein NP_698789.1 1738997 R 204722 CDS NP_698790.1 23502663 1167503 complement(1739598..1739885) 1 NC_004310.3 identified by similarity to EGAD:13628; usg protein 1739885 1167503 BR1810 Brucella suis 1330 usg protein NP_698790.1 1739598 R 204722 CDS NP_698791.1 23502664 1167504 1740226..1742181 1 NC_004310.3 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1742181 1167504 BR1811 Brucella suis 1330 acetyl-CoA synthetase NP_698791.1 1740226 D 204722 CDS NP_698792.1 23502665 1167505 complement(1742337..1742564) 1 NC_004310.3 identified by similarity to GP:14024231; hypothetical protein 1742564 1167505 BR1812 Brucella suis 1330 hypothetical protein NP_698792.1 1742337 R 204722 CDS NP_698793.1 23502666 1167506 1742687..1743664 1 NC_004310.3 metalloprotease; heat shock protein HtpX 1743664 htpX 1167506 htpX Brucella suis 1330 heat shock protein HtpX NP_698793.1 1742687 D 204722 CDS NP_698794.1 23502667 1167507 1743680..1745077 1 NC_004310.3 identified by match to protein family HMM PF01029; match to protein family HMM PF01189; sun protein 1745077 sun 1167507 sun Brucella suis 1330 sun protein NP_698794.1 1743680 D 204722 CDS NP_698795.1 23502668 1167508 1745309..1746940 1 NC_004310.3 identified by similarity to GP:14024235; hypothetical protein 1746940 1167508 BR1815 Brucella suis 1330 hypothetical protein NP_698795.1 1745309 D 204722 CDS NP_698796.1 23502669 1167509 1747047..1748663 1 NC_004310.3 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1748663 purH 1167509 purH Brucella suis 1330 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_698796.1 1747047 D 204722 CDS NP_698797.1 23502670 1167510 complement(1748713..1750080) 1 NC_004310.3 hypothetical protein 1750080 1167510 BR1817 Brucella suis 1330 hypothetical protein NP_698797.1 1748713 R 204722 CDS NP_698798.1 23502671 1167511 1750014..1750322 1 NC_004310.3 hypothetical protein 1750322 1167511 BR1818 Brucella suis 1330 hypothetical protein NP_698798.1 1750014 D 204722 CDS NP_698799.1 23502672 1167512 complement(1750300..1755102) 1 NC_004310.3 identified by similarity to GP:15076346; match to protein family HMM PF05088; match to protein family HMM TIGR01612; hypothetical protein 1755102 1167512 BR1819 Brucella suis 1330 hypothetical protein NP_698799.1 1750300 R 204722 CDS NP_698800.1 23502673 1167513 complement(1755367..1756008) 1 NC_004310.3 identified by similarity to GP:14024253; hypothetical protein 1756008 1167513 BR1820 Brucella suis 1330 hypothetical protein NP_698800.1 1755367 R 204722 CDS NP_698801.1 23502674 1167514 complement(1756021..1756824) 1 NC_004310.3 identified by similarity to GP:14024255; match to protein family HMM PF04536; hypothetical protein 1756824 1167514 BR1821 Brucella suis 1330 hypothetical protein NP_698801.1 1756021 R 204722 CDS NP_698802.1 23502675 1167515 complement(1756905..1757528) 1 NC_004310.3 identified by similarity to EGAD:149857; match to protein family HMM PF04011; hypothetical protein 1757528 1167515 BR1822 Brucella suis 1330 hypothetical protein NP_698802.1 1756905 R 204722 CDS NP_698803.1 23502676 1167516 complement(1757525..1757698) 1 NC_004310.3 hypothetical protein 1757698 1167516 BR1823 Brucella suis 1330 hypothetical protein NP_698803.1 1757525 R 204722 CDS NP_698804.1 23502677 1167517 complement(1757798..1758202) 1 NC_004310.3 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1758202 rpsP 1167517 rpsP Brucella suis 1330 30S ribosomal protein S16 NP_698804.1 1757798 R 204722 CDS NP_698805.1 23502678 1167518 complement(1758269..1758583) 1 NC_004310.3 catalyzes the interconversion of chorismate to prephenate; chorismate mutase 1758583 1167518 BR1825 Brucella suis 1330 chorismate mutase NP_698805.1 1758269 R 204722 CDS NP_698806.1 23502679 1167519 complement(1758589..1760160) 1 NC_004310.3 identified by similarity to EGAD:6526; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein 1760160 ffh 1167519 ffh Brucella suis 1330 signal recognition particle protein NP_698806.1 1758589 R 204722 CDS NP_698807.1 23502680 1167520 1760284..1760655 1 NC_004310.3 hypothetical protein 1760655 1167520 BR1827 Brucella suis 1330 hypothetical protein NP_698807.1 1760284 D 204722 CDS NP_698808.1 23502681 1167521 1760595..1761422 1 NC_004310.3 identified by similarity to OMNI:VC1956; lytic murein transglycosylase 1761422 1167521 BR1828 Brucella suis 1330 lytic murein transglycosylase NP_698808.1 1760595 D 204722 CDS NP_698809.1 23502682 1167522 complement(1761486..1762127) 1 NC_004310.3 identified by match to protein family HMM PF00484; carbonic anhydrase 1762127 1167522 BR1829 Brucella suis 1330 carbonic anhydrase NP_698809.1 1761486 R 204722 CDS NP_698810.1 23502683 1167523 complement(1762301..1763197) 1 NC_004310.3 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase 1763197 1167523 BR1830 Brucella suis 1330 pyridoxamine kinase NP_698810.1 1762301 R 204722 CDS NP_698811.1 23502684 1167524 complement(1763199..1763486) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3181; hypothetical protein 1763486 1167524 BR1831 Brucella suis 1330 hypothetical protein NP_698811.1 1763199 R 204722 CDS NP_698812.1 23502685 1167525 complement(1763859..1765355) 1 NC_004310.3 identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722; methylmalonic acid semialdehyde dehydrogenase 1765355 mmsA 1167525 mmsA Brucella suis 1330 methylmalonic acid semialdehyde dehydrogenase NP_698812.1 1763859 R 204722 CDS NP_698813.1 23502686 1167526 1765483..1766388 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1766388 1167526 BR1833 Brucella suis 1330 LysR family transcriptional regulator NP_698813.1 1765483 D 204722 CDS NP_698814.1 23502687 1167527 complement(1766599..1767243) 1 NC_004310.3 identified by similarity to OMNI:NTL03PA00256; hypothetical protein 1767243 1167527 BR1834 Brucella suis 1330 hypothetical protein NP_698814.1 1766599 R 204722 CDS NP_698815.1 23502688 1167528 1767237..1767629 1 NC_004310.3 hypothetical protein 1767629 1167528 BR1835 Brucella suis 1330 hypothetical protein NP_698815.1 1767237 D 204722 CDS NP_698816.1 23502689 1167529 complement(1767681..1768229) 1 NC_004310.3 hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase 1768229 1167529 BR1836 Brucella suis 1330 dinucleoside polyphosphate hydrolase NP_698816.1 1767681 R 204722 CDS NP_698817.1 23502690 1167530 complement(1768435..1769709) 1 NC_004310.3 identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease 1769709 1167530 BR1837 Brucella suis 1330 carboxyl-terminal protease NP_698817.1 1768435 R 204722 CDS NP_698818.1 23502691 1167531 complement(1769753..1771102) 1 NC_004310.3 hypothetical protein 1771102 1167531 BR1838 Brucella suis 1330 hypothetical protein NP_698818.1 1769753 R 204722 CDS NP_698819.1 23502692 1167532 complement(1771215..1772114) 1 NC_004310.3 hypothetical protein 1772114 1167532 BR1839 Brucella suis 1330 hypothetical protein NP_698819.1 1771215 R 204722 CDS NP_698820.1 23502693 1167533 complement(1772232..1772756) 1 NC_004310.3 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase 1772756 1167533 BR1840 Brucella suis 1330 rRNA large subunit methyltransferase NP_698820.1 1772232 R 204722 CDS NP_698821.1 23502694 1167534 complement(1772775..1773128) 1 NC_004310.3 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; iojap-like protein 1773128 1167534 BR1841 Brucella suis 1330 iojap-like protein NP_698821.1 1772775 R 204722 CDS NP_698822.1 23502695 1167535 complement(1773309..1773893) 1 NC_004310.3 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase 1773893 nadD 1167535 nadD Brucella suis 1330 nicotinic acid mononucleotide adenylyltransferase NP_698822.1 1773309 R 204722 CDS NP_698823.1 23502696 1167536 complement(1773983..1775248) 1 NC_004310.3 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1775248 proA 1167536 proA Brucella suis 1330 gamma-glutamyl phosphate reductase NP_698823.1 1773983 R 204722 CDS NP_698824.1 23502697 1167537 complement(1775276..1776412) 1 NC_004310.3 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 1776412 proB 1167537 proB Brucella suis 1330 gamma-glutamyl kinase NP_698824.1 1775276 R 204722 CDS NP_698825.1 23502698 1167538 complement(1776440..1777465) 1 NC_004310.3 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 1777465 obgE 1167538 obgE Brucella suis 1330 GTPase ObgE NP_698825.1 1776440 R 204722 CDS NP_698826.1 23502699 1167539 complement(1777721..1778557) 1 NC_004310.3 hypothetical protein 1778557 1167539 BR1846 Brucella suis 1330 hypothetical protein NP_698826.1 1777721 R 204722 CDS NP_698827.1 23502700 1167540 complement(1778966..1779523) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1779523 1167540 BR1847 Brucella suis 1330 acetyltransferase NP_698827.1 1778966 R 204722 CDS NP_698828.1 23502701 1167541 complement(1779577..1780227) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1780227 1167541 BR1848 Brucella suis 1330 acetyltransferase NP_698828.1 1779577 R 204722 CDS NP_698829.1 23502702 1167542 complement(1780348..1780617) 1 NC_004310.3 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 1780617 rpmA 1167542 rpmA Brucella suis 1330 50S ribosomal protein L27 NP_698829.1 1780348 R 204722 CDS NP_698830.1 23502703 1167543 complement(1780643..1781071) 1 NC_004310.3 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 1781071 rplU 1167543 rplU Brucella suis 1330 50S ribosomal protein L21 NP_698830.1 1780643 R 204722 CDS NP_698831.1 23502704 1167545 1781793..1782479 1 NC_004310.3 transposase 1782479 1167545 BR1851 Brucella suis 1330 transposase NP_698831.1 1781793 D 204722 CDS NP_698832.1 23502705 1167546 1782720..1784648 1 NC_004310.3 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1784648 1167546 BR1852 Brucella suis 1330 Cro/CI family transcriptional regulator NP_698832.1 1782720 D 204722 CDS NP_698833.1 23502706 1167547 1784645..1785319 1 NC_004310.3 identified by match to protein family HMM PF03591; AzlC family protein 1785319 1167547 BR1853 Brucella suis 1330 AzlC family protein NP_698833.1 1784645 D 204722 CDS NP_698834.1 23502707 1167548 1785732..1785845 1 NC_004310.3 hypothetical protein 1785845 1167548 BR1854 Brucella suis 1330 hypothetical protein NP_698834.1 1785732 D 204722 CDS NP_698835.1 23502708 1167549 complement(1785878..1786564) 1 NC_004310.3 transposase 1786564 1167549 BR1855 Brucella suis 1330 transposase NP_698835.1 1785878 R 204722 CDS NP_698836.1 23502709 1167550 complement(1786675..1788114) 1 NC_004310.3 identified by similarity to OMNI:CC1732; hypothetical protein 1788114 1167550 BR1856 Brucella suis 1330 hypothetical protein NP_698836.1 1786675 R 204722 CDS NP_698837.1 23502710 1167551 complement(1788290..1788964) 1 NC_004310.3 hypothetical protein 1788964 1167551 BR1857 Brucella suis 1330 hypothetical protein NP_698837.1 1788290 R 204722 CDS NP_698838.1 23502711 1167552 1789282..1789449 1 NC_004310.3 hypothetical protein 1789449 1167552 BR1858 Brucella suis 1330 hypothetical protein NP_698838.1 1789282 D 204722 CDS NP_698839.1 23502712 1167555 1789837..1789989 1 NC_004310.3 hypothetical protein 1789989 1167555 BR1859 Brucella suis 1330 hypothetical protein NP_698839.1 1789837 D 204722 CDS NP_698840.1 23502713 1167557 1792944..1793186 1 NC_004310.3 hypothetical protein 1793186 1167557 BR1860 Brucella suis 1330 hypothetical protein NP_698840.1 1792944 D 204722 CDS NP_698841.1 23502714 1167561 1796102..1798057 1 NC_004310.3 identified by match to protein family HMM PF01551; M24/M37 family peptidase 1798057 1167561 BR1861 Brucella suis 1330 M24/M37 family peptidase NP_698841.1 1796102 D 204722 CDS NP_698842.1 23502715 1167562 complement(1798125..1799351) 1 NC_004310.3 identified by similarity to GP:15075231; match to protein family HMM PF03734; hypothetical protein 1799351 1167562 BR1862 Brucella suis 1330 hypothetical protein NP_698842.1 1798125 R 204722 CDS NP_698843.1 23502716 1167563 1799400..1799525 1 NC_004310.3 hypothetical protein 1799525 1167563 BR1863 Brucella suis 1330 hypothetical protein NP_698843.1 1799400 D 204722 CDS NP_698844.1 23502717 1167564 complement(1800024..1802648) 1 NC_004310.3 identified by similarity to EGAD:20010; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01369; ATP-dependent Clp protease, ATP-binding subunit ClpB 1802648 clpB 1167564 clpB Brucella suis 1330 ATP-dependent Clp protease, ATP-binding subunit ClpB NP_698844.1 1800024 R 204722 CDS NP_698845.1 23502718 1167565 complement(1802847..1803605) 1 NC_004310.3 identified by similarity to GP:15159086; hypothetical protein 1803605 1167565 BR1865 Brucella suis 1330 hypothetical protein NP_698845.1 1802847 R 204722 CDS NP_698846.1 23502719 1167566 complement(1803586..1803858) 1 NC_004310.3 hypothetical protein 1803858 1167566 BR1866 Brucella suis 1330 hypothetical protein NP_698846.1 1803586 R 204722 CDS NP_698847.1 23502720 1167567 1803920..1804066 1 NC_004310.3 hypothetical protein 1804066 1167567 BR1867 Brucella suis 1330 hypothetical protein NP_698847.1 1803920 D 204722 CDS NP_698848.1 23502721 1167568 complement(1804050..1804901) 1 NC_004310.3 identified by match to protein family HMM TIGR00536; hemK protein 1804901 1167568 BR1868 Brucella suis 1330 hemK protein NP_698848.1 1804050 R 204722 CDS NP_698849.1 23502722 1167569 complement(1804934..1806013) 1 NC_004310.3 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 1806013 prfA 1167569 prfA Brucella suis 1330 peptide chain release factor 1 NP_698849.1 1804934 R 204722 CDS NP_698850.1 23502723 1167570 complement(1806210..1808480) 1 NC_004310.3 identified by similarity to EGAD:36619; match to protein family HMM PF00391; match to protein family HMM PF01590; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase 1808480 ptsP 1167570 ptsP Brucella suis 1330 phosphoenolpyruvate-protein phosphotransferase NP_698850.1 1806210 R 204722 CDS NP_698851.1 23502724 1167571 complement(1808808..1810079) 1 NC_004310.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 1810079 1167571 BR1871 Brucella suis 1330 aspartate kinase NP_698851.1 1808808 R 204722 CDS NP_698852.1 23502725 1167572 1810297..1811043 1 NC_004310.3 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1811043 ubiG 1167572 ubiG Brucella suis 1330 3-demethylubiquinone-9 3-methyltransferase NP_698852.1 1810297 D 204722 CDS NP_698853.1 23502726 1167573 complement(1811049..1811930) 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 1811930 1167573 BR1873 Brucella suis 1330 hypothetical protein NP_698853.1 1811049 R 204722 CDS NP_698854.1 23502727 1167574 complement(1811970..1812428) 1 NC_004310.3 identified by similarity to GP:15159831; hypothetical protein 1812428 1167574 BR1874 Brucella suis 1330 hypothetical protein NP_698854.1 1811970 R 204722 CDS NP_698855.1 23502728 1167575 complement(1812401..1813255) 1 NC_004310.3 identified by match to protein family HMM PF00795; carbon-nitrogen hydrolase 1813255 1167575 BR1875 Brucella suis 1330 carbon-nitrogen hydrolase NP_698855.1 1812401 R 204722 CDS NP_698856.1 23502729 1167576 complement(1813266..1813532) 1 NC_004310.3 identified by similarity to SP:P37687; match to protein family HMM PF00462; glutaredoxin 3 1813532 grxC 1167576 grxC Brucella suis 1330 glutaredoxin 3 NP_698856.1 1813266 R 204722 CDS NP_698857.1 23502730 1167577 1813516..1813638 1 NC_004310.3 hypothetical protein 1813638 1167577 BR1877 Brucella suis 1330 hypothetical protein NP_698857.1 1813516 D 204722 CDS NP_698858.1 23502731 1167578 complement(1813616..1814404) 1 NC_004310.3 identified by similarity to EGAD:18112; competence protein F 1814404 1167578 BR1878 Brucella suis 1330 competence protein F NP_698858.1 1813616 R 204722 CDS NP_698859.1 23502732 1167579 1814587..1815480 1 NC_004310.3 identified by similarity to GP:15075644; hypothetical protein 1815480 1167579 BR1879 Brucella suis 1330 hypothetical protein NP_698859.1 1814587 D 204722 CDS NP_698860.1 23502733 1167580 complement(1815546..1815680) 1 NC_004310.3 hypothetical protein 1815680 1167580 BR1880 Brucella suis 1330 hypothetical protein NP_698860.1 1815546 R 204722 CDS NP_698861.1 23502734 1167582 complement(1816884..1817363) 1 NC_004310.3 identified by similarity to GP:14024323; hypothetical protein 1817363 1167582 BR1882 Brucella suis 1330 hypothetical protein NP_698861.1 1816884 R 204722 CDS NP_698862.1 23502735 1167583 1817640..1817732 1 NC_004310.3 hypothetical protein 1817732 1167583 BR1883 Brucella suis 1330 hypothetical protein NP_698862.1 1817640 D 204722 CDS NP_698863.1 23502736 1167584 complement(1817779..1819350) 1 NC_004310.3 identified by similarity to GP:15076107; hypothetical protein 1819350 1167584 BR1884 Brucella suis 1330 hypothetical protein NP_698863.1 1817779 R 204722 CDS NP_698864.1 23502737 1167585 complement(1819363..1820739) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3249; hypothetical protein 1820739 1167585 BR1885 Brucella suis 1330 hypothetical protein NP_698864.1 1819363 R 204722 CDS NP_698865.1 23502738 1167586 complement(1820822..1821529) 1 NC_004310.3 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; uroporphyrinogen-III synthase 1821529 hemD 1167586 hemD Brucella suis 1330 uroporphyrinogen-III synthase NP_698865.1 1820822 R 204722 CDS NP_698866.1 23502739 1167587 complement(1821553..1822497) 1 NC_004310.3 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 1822497 hemC 1167587 hemC Brucella suis 1330 porphobilinogen deaminase NP_698866.1 1821553 R 204722 CDS NP_698867.1 23502740 1167588 1822616..1823695 1 NC_004310.3 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1823695 gcp 1167588 gcp Brucella suis 1330 DNA-binding/iron metalloprotein/AP endonuclease NP_698867.1 1822616 D 204722 CDS NP_698868.1 23502741 1167589 1823692..1824672 1 NC_004310.3 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1824672 gpsA 1167589 gpsA Brucella suis 1330 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase NP_698868.1 1823692 D 204722 CDS NP_698869.1 23502742 1167590 1824674..1824964 1 NC_004310.3 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1824964 1167590 BR1890 Brucella suis 1330 hypothetical protein NP_698869.1 1824674 D 204722 CDS NP_698870.1 23502743 1167591 1824977..1825405 1 NC_004310.3 identified by similarity to GP:15157855; match to protein family HMM PF04543; hypothetical protein 1825405 1167591 BR1891 Brucella suis 1330 hypothetical protein NP_698870.1 1824977 D 204722 CDS NP_698871.1 23502744 1167592 1825405..1826061 1 NC_004310.3 identified by similarity to GP:15076099; hypothetical protein 1826061 1167592 BR1892 Brucella suis 1330 hypothetical protein NP_698871.1 1825405 D 204722 CDS NP_698872.1 23502745 1167593 complement(1826107..1826964) 1 NC_004310.3 identified by match to protein family HMM PF00892; hypothetical protein 1826964 1167593 BR1893 Brucella suis 1330 hypothetical protein NP_698872.1 1826107 R 204722 CDS NP_698873.1 23502746 1167595 complement(1828634..1831198) 1 NC_004310.3 identified by similarity to EGAD:30442; match to protein family HMM PF01580; DNA translocase FtsK 1831198 1167595 BR1895 Brucella suis 1330 DNA translocase FtsK NP_698873.1 1828634 R 204722 CDS NP_698874.1 23502747 1167596 complement(1831408..1832709) 1 NC_004310.3 identified by similarity to GP:3136068; match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter 1832709 amt 1167596 amt Brucella suis 1330 ammonium transporter NP_698874.1 1831408 R 204722 CDS NP_698875.1 23502748 1167597 1832683..1832841 1 NC_004310.3 hypothetical protein 1832841 1167597 BR1897 Brucella suis 1330 hypothetical protein NP_698875.1 1832683 D 204722 CDS NP_698876.1 23502749 1167598 complement(1832898..1833833) 1 NC_004310.3 identified by similarity to SP:P23911; match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase 1833833 tesB 1167598 tesB Brucella suis 1330 acyl-CoA thioesterase NP_698876.1 1832898 R 204722 CDS NP_698877.1 23502750 1167599 1834053..1835297 1 NC_004310.3 identified by match to protein family HMM PF01360; 2-octaprenyl-6-methoxyphenyl hydroxylase 1835297 1167599 BR1899 Brucella suis 1330 2-octaprenyl-6-methoxyphenyl hydroxylase NP_698877.1 1834053 D 204722 CDS NP_698878.1 23502751 1167600 complement(1835383..1835754) 1 NC_004310.3 identified by match to protein family HMM PF00903; glyoxalase 1835754 1167600 BR1900 Brucella suis 1330 glyoxalase NP_698878.1 1835383 R 204722 CDS NP_698879.1 23502752 1167601 complement(1836001..1836780) 1 NC_004310.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 1836780 sdhB 1167601 sdhB Brucella suis 1330 succinate dehydrogenase iron-sulfur subunit NP_698879.1 1836001 R 204722 CDS NP_698880.1 23502753 1167602 complement(1836796..1838637) 1 NC_004310.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 1838637 sdhA 1167602 sdhA Brucella suis 1330 succinate dehydrogenase flavoprotein subunit NP_698880.1 1836796 R 204722 CDS NP_698881.1 23502754 1167603 complement(1838645..1839040) 1 NC_004310.3 identified by similarity to EGAD:23053; match to protein family HMM PF01127; succinate dehydrogenase, hydrophobic membrane anchor protein 1839040 1167603 BR1903 Brucella suis 1330 succinate dehydrogenase, hydrophobic membrane anchor protein NP_698881.1 1838645 R 204722 CDS NP_698882.1 23502755 1167604 complement(1839054..1839452) 1 NC_004310.3 identified by similarity to EGAD:15755; match to protein family HMM PF01127; succinate dehydrogenase, cytochrome b556 subunit 1839452 sdhC 1167604 sdhC Brucella suis 1330 succinate dehydrogenase, cytochrome b556 subunit NP_698882.1 1839054 R 204722 CDS NP_698883.1 23502756 1167605 complement(1839797..1840255) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1840255 1167605 BR1905 Brucella suis 1330 acetyltransferase NP_698883.1 1839797 R 204722 CDS NP_698884.1 23502757 1167606 complement(1840512..1841921) 1 NC_004310.3 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 1841921 leuC 1167606 leuC Brucella suis 1330 isopropylmalate isomerase large subunit NP_698884.1 1840512 R 204722 CDS NP_698885.1 23502758 1167607 complement(1842132..1842569) 1 NC_004310.3 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1842569 rplS 1167607 rplS Brucella suis 1330 50S ribosomal protein L19 NP_698885.1 1842132 R 204722 CDS NP_698886.1 23502759 1167608 1842861..1844324 1 NC_004310.3 identified by match to protein family HMM PF02133; NCS1 nucleoside transporter family protein 1844324 1167608 BR1908 Brucella suis 1330 NCS1 nucleoside transporter family protein NP_698886.1 1842861 D 204722 CDS NP_698887.1 23502760 1167610 complement(1844725..1845135) 1 NC_004310.3 identified by similarity to GP:7739616; hypothetical protein 1845135 1167610 BR1910 Brucella suis 1330 hypothetical protein NP_698887.1 1844725 R 204722 CDS NP_698888.1 23502761 1167611 complement(1845128..1845490) 1 NC_004310.3 identified by similarity to GP:15156392; match to protein family HMM PF03992; hypothetical protein 1845490 1167611 BR1911 Brucella suis 1330 hypothetical protein NP_698888.1 1845128 R 204722 CDS NP_698889.1 23502762 1167612 complement(1845487..1845810) 1 NC_004310.3 identified by similarity to GP:15156391; hypothetical protein 1845810 1167612 BR1912 Brucella suis 1330 hypothetical protein NP_698889.1 1845487 R 204722 CDS NP_698890.1 23502763 1167613 1845881..1846546 1 NC_004310.3 identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1846546 1167613 BR1913 Brucella suis 1330 ArsR family transcriptional regulator NP_698890.1 1845881 D 204722 CDS NP_698891.1 23502764 1167614 complement(1846681..1847415) 1 NC_004310.3 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1847415 trmD 1167614 trmD Brucella suis 1330 tRNA (guanine-N(1)-)-methyltransferase NP_698891.1 1846681 R 204722 CDS NP_698892.1 23502765 1167615 complement(1847412..1847981) 1 NC_004310.3 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1847981 rimM 1167615 rimM Brucella suis 1330 16S rRNA-processing protein RimM NP_698892.1 1847412 R 204722 CDS NP_698893.1 23502766 1167616 1848205..1849152 1 NC_004310.3 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1849152 xerC 1167616 xerC Brucella suis 1330 site-specific tyrosine recombinase XerC NP_698893.1 1848205 D 204722 CDS NP_698894.1 23502767 1167617 1849206..1850207 1 NC_004310.3 identified by similarity to GP:15157831; hypothetical protein 1850207 1167617 BR1917 Brucella suis 1330 hypothetical protein NP_698894.1 1849206 D 204722 CDS NP_698895.1 23502768 1167618 complement(1850411..1851814) 1 NC_004310.3 Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 1851814 lpdA-2 1167618 lpdA-2 Brucella suis 1330 dihydrolipoamide dehydrogenase NP_698895.1 1850411 R 204722 CDS NP_698896.1 23502769 1167619 complement(1851983..1852525) 1 NC_004310.3 identified by similarity to GP:14024383; hypothetical protein 1852525 1167619 BR1919 Brucella suis 1330 hypothetical protein NP_698896.1 1851983 R 204722 CDS NP_698897.1 23502770 1167620 complement(1852596..1853234) 1 NC_004310.3 identified by match to protein family HMM PF01810; amino acid transporter LysE 1853234 1167620 BR1920 Brucella suis 1330 amino acid transporter LysE NP_698897.1 1852596 R 204722 CDS NP_698898.1 23502771 1167621 complement(1853276..1853689) 1 NC_004310.3 identified by similarity to GP:15157838; match to protein family HMM PF01124; hypothetical protein 1853689 1167621 BR1921 Brucella suis 1330 hypothetical protein NP_698898.1 1853276 R 204722 CDS NP_698899.1 23502772 1167622 complement(1853699..1854925) 1 NC_004310.3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase 1854925 sucB 1167622 sucB Brucella suis 1330 dihydrolipoamide succinyltransferase NP_698899.1 1853699 R 204722 CDS NP_698900.1 23502773 1167623 complement(1854987..1858001) 1 NC_004310.3 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 1858001 sucA 1167623 sucA Brucella suis 1330 2-oxoglutarate dehydrogenase E1 NP_698900.1 1854987 R 204722 CDS NP_698901.1 23502774 1167624 1858138..1858287 1 NC_004310.3 hypothetical protein 1858287 1167624 BR1924 Brucella suis 1330 hypothetical protein NP_698901.1 1858138 D 204722 CDS NP_698902.1 23502775 1167625 complement(1858277..1859179) 1 NC_004310.3 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha 1859179 sucD 1167625 sucD Brucella suis 1330 succinyl-CoA synthetase subunit alpha NP_698902.1 1858277 R 204722 CDS NP_698903.1 23502776 1167626 complement(1859183..1860379) 1 NC_004310.3 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 1860379 sucC 1167626 sucC Brucella suis 1330 succinyl-CoA synthetase subunit beta NP_698903.1 1859183 R 204722 CDS NP_698904.1 23502777 1167627 complement(1860486..1861448) 1 NC_004310.3 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 1861448 mdh 1167627 mdh Brucella suis 1330 malate dehydrogenase NP_698904.1 1860486 R 204722 CDS NP_698905.1 23502778 1167628 complement(1861568..1861810) 1 NC_004310.3 hypothetical protein 1861810 1167628 BR1928 Brucella suis 1330 hypothetical protein NP_698905.1 1861568 R 204722 CDS NP_698906.1 23502779 1167629 complement(1861887..1863050) 1 NC_004310.3 identified by similarity to GP:15076082; match to protein family HMM PF03969; hypothetical protein 1863050 1167629 BR1929 Brucella suis 1330 hypothetical protein NP_698906.1 1861887 R 204722 CDS NP_698907.1 23502780 1167630 complement(1863170..1863703) 1 NC_004310.3 identified by similarity to GP:954748; lipoprotein Omp19 1863703 omp19 1167630 omp19 Brucella suis 1330 lipoprotein Omp19 NP_698907.1 1863170 R 204722 CDS NP_698908.1 23502781 1167631 complement(1863833..1864036) 1 NC_004310.3 hypothetical protein 1864036 1167631 BR1931 Brucella suis 1330 hypothetical protein NP_698908.1 1863833 R 204722 CDS NP_698909.1 23502782 1167632 1864067..1864978 1 NC_004310.3 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1864978 dapF 1167632 dapF Brucella suis 1330 diaminopimelate epimerase NP_698909.1 1864067 D 204722 CDS NP_698910.1 23502783 1167633 1864978..1866261 1 NC_004310.3 identified by similarity to GP:15076264; match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; hypothetical protein 1866261 1167633 BR1933 Brucella suis 1330 hypothetical protein NP_698910.1 1864978 D 204722 CDS NP_698911.1 23502784 1167634 1866289..1867680 1 NC_004310.3 identified by similarity to EGAD:5681; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 1867680 ftsY 1167634 ftsY Brucella suis 1330 signal recognition particle-docking protein FtsY NP_698911.1 1866289 D 204722 CDS NP_698912.1 23502785 1167635 1867680..1868342 1 NC_004310.3 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1868342 ispZ 1167635 ispZ Brucella suis 1330 intracellular septation protein A NP_698912.1 1867680 D 204722 CDS NP_698913.1 23502786 1167636 1868375..1869148 1 NC_004310.3 identified by similarity to EGAD:35929; match to protein family HMM PF00753; hydroxyacylglutathione hydrolase 1869148 1167636 BR1936 Brucella suis 1330 hydroxyacylglutathione hydrolase NP_698913.1 1868375 D 204722 CDS NP_698914.1 23502787 1167637 1869195..1869686 1 NC_004310.3 hypothetical protein 1869686 1167637 BR1937 Brucella suis 1330 hypothetical protein NP_698914.1 1869195 D 204722 CDS NP_698915.1 23502788 1167638 complement(1869751..1870056) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2661; hypothetical protein 1870056 1167638 BR1938 Brucella suis 1330 hypothetical protein NP_698915.1 1869751 R 204722 CDS NP_698916.1 23502789 1167639 complement(1870168..1870584) 1 NC_004310.3 identified by similarity to EGAD:16514; match to protein family HMM PF00293; mutator mutT protein 1870584 1167639 BR1939 Brucella suis 1330 mutator mutT protein NP_698916.1 1870168 R 204722 CDS NP_698917.1 23502790 1167640 complement(1870581..1871372) 1 NC_004310.3 identified by match to protein family HMM PF00583; acetyltransferase 1871372 1167640 BR1940 Brucella suis 1330 acetyltransferase NP_698917.1 1870581 R 204722 CDS NP_698918.1 23502791 1167641 complement(1871430..1872671) 1 NC_004310.3 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase 1872671 argJ 1167641 argJ Brucella suis 1330 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase NP_698918.1 1871430 R 204722 CDS NP_698919.1 23502792 1167642 complement(1872905..1873048) 1 NC_004310.3 hypothetical protein 1873048 1167642 BR1942 Brucella suis 1330 hypothetical protein NP_698919.1 1872905 R 204722 CDS NP_698920.1 23502793 1167643 complement(1873109..1874104) 1 NC_004310.3 identified by similarity to EGAD:7364; match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase 1874104 1167643 BR1943 Brucella suis 1330 peptidyl-prolyl cis-trans isomerase NP_698920.1 1873109 R 204722 CDS NP_698921.1 23502794 1167644 complement(1874232..1874399) 1 NC_004310.3 hypothetical protein 1874399 1167644 BR1944 Brucella suis 1330 hypothetical protein NP_698921.1 1874232 R 204722 CDS NP_698922.1 23502795 1167645 1874443..1877163 1 NC_004310.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1877163 secA 1167645 secA Brucella suis 1330 preprotein translocase subunit SecA NP_698922.1 1874443 D 204722 CDS NP_698923.1 23502796 1167646 1877191..1877331 1 NC_004310.3 hypothetical protein 1877331 1167646 BR1946 Brucella suis 1330 hypothetical protein NP_698923.1 1877191 D 204722 CDS NP_698924.1 23502797 1167647 1877940..1879226 1 NC_004310.3 identified by similarity to GP:14023746; hypothetical protein 1879226 1167647 BR1947 Brucella suis 1330 hypothetical protein NP_698924.1 1877940 D 204722 CDS NP_698925.1 23502798 1167648 1879395..1881029 1 NC_004310.3 identified by match to protein family HMM PF00884; match to protein family HMM PF02418; hypothetical protein 1881029 1167648 BR1948 Brucella suis 1330 hypothetical protein NP_698925.1 1879395 D 204722 CDS NP_698926.1 23502799 1167649 1881383..1881484 1 NC_004310.3 hypothetical protein 1881484 1167649 BR1949 Brucella suis 1330 hypothetical protein NP_698926.1 1881383 D 204722 CDS NP_698927.1 23502800 1167651 complement(1881867..1882076) 1 NC_004310.3 hypothetical protein 1882076 1167651 BR1950 Brucella suis 1330 hypothetical protein NP_698927.1 1881867 R 204722 CDS NP_698928.1 23502801 1167652 complement(1882197..1883180) 1 NC_004310.3 identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1883180 1167652 BR1951 Brucella suis 1330 LysR family transcriptional regulator NP_698928.1 1882197 R 204722 CDS NP_698929.1 23502802 1167653 complement(1883220..1883405) 1 NC_004310.3 hypothetical protein 1883405 1167653 BR1952 Brucella suis 1330 hypothetical protein NP_698929.1 1883220 R 204722 CDS NP_698930.1 23502803 1167654 1883471..1884316 1 NC_004310.3 identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1884316 1167654 BR1953 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_698930.1 1883471 D 204722 CDS NP_698931.1 23502804 1167656 1885107..1885829 1 NC_004310.3 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1885829 1167656 BR1955 Brucella suis 1330 amino acid ABC transporter permease NP_698931.1 1885107 D 204722 CDS NP_698932.1 23502805 1167657 1885826..1886641 1 NC_004310.3 identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1886641 1167657 BR1956 Brucella suis 1330 amino acid ABC transporter ATP-binding protein NP_698932.1 1885826 D 204722 CDS NP_698933.1 23502806 1167658 1886662..1887675 1 NC_004310.3 identified by match to protein family HMM PF00491; arginase 1887675 1167658 BR1957 Brucella suis 1330 arginase NP_698933.1 1886662 D 204722 CDS NP_698934.1 23502807 1167659 1887684..1889135 1 NC_004310.3 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1889135 aspA 1167659 aspA Brucella suis 1330 aspartate ammonia-lyase NP_698934.1 1887684 D 204722 CDS NP_698935.1 23502808 1167660 1889119..1889874 1 NC_004310.3 identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1889874 1167660 BR1959 Brucella suis 1330 amino acid ABC transporter ATP-binding protein NP_698935.1 1889119 D 204722 CDS NP_698936.1 23502809 1167661 1889883..1890881 1 NC_004310.3 identified by similarity to EGAD:14317; match to protein family HMM PF00710; L-asparaginase type II 1890881 1167661 BR1960 Brucella suis 1330 L-asparaginase type II NP_698936.1 1889883 D 204722 CDS NP_698937.1 23502810 1167662 complement(1891018..1891701) 1 NC_004310.3 identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1891701 1167662 BR1961 Brucella suis 1330 GntR family transcriptional regulator NP_698937.1 1891018 R 204722 CDS NP_698938.1 23502811 1167663 complement(1891725..1892714) 1 NC_004310.3 identified by similarity to SP:P43843; match to protein family HMM PF00710; asparaginase 1892714 1167663 BR1962 Brucella suis 1330 asparaginase NP_698938.1 1891725 R 204722 CDS NP_698939.1 23502812 1167664 1892792..1894099 1 NC_004310.3 identified by match to protein family HMM PF00083; major facilitator family transporter 1894099 1167664 BR1963 Brucella suis 1330 major facilitator family transporter NP_698939.1 1892792 D 204722 CDS NP_698940.1 23502813 1167665 complement(1894586..1894738) 1 NC_004310.3 hypothetical protein 1894738 1167665 BR1964 Brucella suis 1330 hypothetical protein NP_698940.1 1894586 R 204722 CDS NP_698941.1 23502814 1167666 complement(1894785..1896068) 1 NC_004310.3 catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase 1896068 1167666 BR1965 Brucella suis 1330 methionine gamma-lyase NP_698941.1 1894785 R 204722 CDS NP_698942.1 23502815 1167667 complement(1896248..1896697) 1 NC_004310.3 identified by match to protein family HMM PF00582; universal stress protein 1896697 1167667 BR1966 Brucella suis 1330 universal stress protein NP_698942.1 1896248 R 204722 CDS NP_698943.1 23502816 1167669 complement(1898009..1898257) 1 NC_004310.3 hypothetical protein 1898257 1167669 BR1968 Brucella suis 1330 hypothetical protein NP_698943.1 1898009 R 204722 CDS NP_698944.1 23502817 1167670 complement(1898417..1899292) 1 NC_004310.3 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase 1899292 hbd 1167670 hbd Brucella suis 1330 3-hydroxybutyryl-CoA dehydrogenase NP_698944.1 1898417 R 204722 CDS NP_698945.1 23502818 1167671 complement(1899776..1900705) 1 NC_004310.3 identified by similarity to SP:P38974; match to protein family HMM PF00766; electron transfer flavoprotein subunit alpha 1900705 etfA 1167671 etfA Brucella suis 1330 electron transfer flavoprotein subunit alpha NP_698945.1 1899776 R 204722 CDS NP_698946.1 23502819 1167672 complement(1900858..1901604) 1 NC_004310.3 identified by similarity to EGAD:17375; match to protein family HMM PF01012; electron transfer flavoprotein subunit beta 1901604 etfB 1167672 etfB Brucella suis 1330 electron transfer flavoprotein subunit beta NP_698946.1 1900858 R 204722 CDS NP_698947.1 23502820 1167673 1901940..1902638 1 NC_004310.3 identified by match to protein family HMM TIGR00364; exoenzyme S synthesis protein B 1902638 1167673 BR1972 Brucella suis 1330 exoenzyme S synthesis protein B NP_698947.1 1901940 D 204722 CDS NP_698948.1 23502821 1167674 1902638..1903003 1 NC_004310.3 identified by match to protein family HMM PF01242; 6-pyruvoyl tetrahydrobiopterin synthase 1903003 1167674 BR1973 Brucella suis 1330 6-pyruvoyl tetrahydrobiopterin synthase NP_698948.1 1902638 D 204722 CDS NP_698949.1 23502822 1167675 1903003..1903758 1 NC_004310.3 identified by match to protein family HMM PF04055; radical activating enzyme 1903758 1167675 BR1974 Brucella suis 1330 radical activating enzyme NP_698949.1 1903003 D 204722 CDS NP_698950.1 23502823 1167676 complement(1903895..1904482) 1 NC_004310.3 identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; ATP:cob(I)alamin adenosyltransferase 1904482 1167676 BR1975 Brucella suis 1330 ATP:cob(I)alamin adenosyltransferase NP_698950.1 1903895 R 204722 CDS NP_698951.1 23502824 1167677 complement(1904484..1904651) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2682; hypothetical protein 1904651 1167677 BR1976 Brucella suis 1330 hypothetical protein NP_698951.1 1904484 R 204722 CDS NP_698952.1 23502825 1167678 complement(1904717..1905559) 1 NC_004310.3 identified by match to protein family HMM PF00106; short chain dehydrogenase 1905559 1167678 BR1977 Brucella suis 1330 short chain dehydrogenase NP_698952.1 1904717 R 204722 CDS NP_698953.1 23502826 1167679 1905717..1906577 1 NC_004310.3 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; ribonuclease BN 1906577 1167679 BR1978 Brucella suis 1330 ribonuclease BN NP_698953.1 1905717 D 204722 CDS NP_698954.1 23502827 1167680 1906595..1907080 1 NC_004310.3 identified by match to protein family HMM PF02639; hypothetical protein 1907080 1167680 BR1979 Brucella suis 1330 hypothetical protein NP_698954.1 1906595 D 204722 CDS NP_698955.1 23502828 1167681 complement(1907088..1907804) 1 NC_004310.3 thiol:disulfide interchange protein 1907804 1167681 BR1980 Brucella suis 1330 thiol:disulfide interchange protein NP_698955.1 1907088 R 204722 CDS NP_698956.1 23502829 1167682 1907858..1909258 1 NC_004310.3 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1909258 argH 1167682 argH Brucella suis 1330 argininosuccinate lyase NP_698956.1 1907858 D 204722 CDS NP_698957.1 23502830 1167683 1909363..1909551 1 NC_004310.3 hypothetical protein 1909551 1167683 BR1982 Brucella suis 1330 hypothetical protein NP_698957.1 1909363 D 204722 CDS NP_698958.1 23502831 1167684 1909579..1910844 1 NC_004310.3 identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1910844 lysA 1167684 lysA Brucella suis 1330 diaminopimelate decarboxylase NP_698958.1 1909579 D 204722 CDS NP_698959.1 23502832 1167685 1910943..1913588 1 NC_004310.3 identified by similarity to GP:15075674; hypothetical protein 1913588 1167685 BR1984 Brucella suis 1330 hypothetical protein NP_698959.1 1910943 D 204722 CDS NP_698960.1 23502833 1167686 complement(1913628..1914164) 1 NC_004310.3 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase 1914164 hpt 1167686 hpt Brucella suis 1330 hypoxanthine-guanine phosphoribosyltransferase NP_698960.1 1913628 R 204722 CDS NP_698961.1 23502834 1167687 1914313..1915092 1 NC_004310.3 identified by similarity to GP:15075687; hypothetical protein 1915092 1167687 BR1986 Brucella suis 1330 hypothetical protein NP_698961.1 1914313 D 204722 CDS NP_698962.1 23502835 1167688 1915246..1916343 1 NC_004310.3 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1916343 hisC 1167688 hisC Brucella suis 1330 histidinol-phosphate aminotransferase NP_698962.1 1915246 D 204722 CDS NP_698963.1 23502836 1167689 1916348..1917313 1 NC_004310.3 dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1917313 tyrC 1167689 tyrC Brucella suis 1330 cyclohexadienyl dehydrogenase NP_698963.1 1916348 D 204722 CDS NP_698964.1 23502837 1167690 complement(1917282..1918301) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2723; hypothetical protein 1918301 1167690 BR1989 Brucella suis 1330 hypothetical protein NP_698964.1 1917282 R 204722 CDS NP_698965.1 23502838 1167691 complement(1918321..1918524) 1 NC_004310.3 hypothetical protein 1918524 1167691 BR1990 Brucella suis 1330 hypothetical protein NP_698965.1 1918321 R 204722 CDS NP_698966.1 23502839 1167692 1918513..1919073 1 NC_004310.3 identified by similarity to SP:P39163; match to protein family HMM PF04752; cation transport protein 1919073 1167692 BR1991 Brucella suis 1330 cation transport protein NP_698966.1 1918513 D 204722 CDS NP_698967.1 23502840 1167694 1919406..1919696 1 NC_004310.3 identified by similarity to EGAD:140445; match to protein family HMM PF02325; hypothetical protein 1919696 1167694 BR1992 Brucella suis 1330 hypothetical protein NP_698967.1 1919406 D 204722 CDS NP_698968.1 23502841 1167695 complement(1919867..1920397) 1 NC_004310.3 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 1920397 ppa 1167695 ppa Brucella suis 1330 inorganic pyrophosphatase NP_698968.1 1919867 R 204722 CDS NP_698969.1 23502842 1167696 complement(1920550..1921332) 1 NC_004310.3 identified by match to protein family HMM PF01553; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1921332 1167696 BR1994 Brucella suis 1330 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_698969.1 1920550 R 204722 CDS NP_698970.1 23502843 1167697 complement(1921511..1922149) 1 NC_004310.3 identified by similarity to GP:15075681; hypothetical protein 1922149 1167697 BR1995 Brucella suis 1330 hypothetical protein NP_698970.1 1921511 R 204722 CDS NP_698971.1 23502844 1167698 complement(1922410..1923411) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2714; hypothetical protein 1923411 1167698 BR1996 Brucella suis 1330 hypothetical protein NP_698971.1 1922410 R 204722 CDS NP_698972.1 23502845 1167699 complement(1923404..1924063) 1 NC_004310.3 identified by similarity to EGAD:7038; match to protein family HMM PF00005; cell division ABC transporter ATP-binding protein FtsE 1924063 ftsE 1167699 ftsE Brucella suis 1330 cell division ABC transporter ATP-binding protein FtsE NP_698972.1 1923404 R 204722 CDS NP_698973.1 23502846 1167700 complement(1924068..1924250) 1 NC_004310.3 hypothetical protein 1924250 1167700 BR1998 Brucella suis 1330 hypothetical protein NP_698973.1 1924068 R 204722 CDS NP_698974.1 23502847 1167701 1924319..1924738 1 NC_004310.3 hypothetical protein 1924738 1167701 BR1999 Brucella suis 1330 hypothetical protein NP_698974.1 1924319 D 204722 CDS NP_698975.1 23502848 1167702 complement(1924775..1924876) 1 NC_004310.3 hypothetical protein 1924876 1167702 BR2000 Brucella suis 1330 hypothetical protein NP_698975.1 1924775 R 204722 CDS NP_698976.1 23502849 1167703 1925122..1925808 1 NC_004310.3 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1925808 aqpZ 1167703 aqpZ Brucella suis 1330 aquaporin Z NP_698976.1 1925122 D 204722 CDS NP_698977.1 23502850 1167704 complement(1925809..1925940) 1 NC_004310.3 hypothetical protein 1925940 1167704 BR2002 Brucella suis 1330 hypothetical protein NP_698977.1 1925809 R 204722 CDS NP_698978.1 23502851 1167705 1926192..1926884 1 NC_004310.3 identified by similarity to GP:15157980; hypothetical protein 1926884 1167705 BR2003 Brucella suis 1330 hypothetical protein NP_698978.1 1926192 D 204722 CDS NP_698979.1 23502852 1167706 1926987..1927793 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3264; match to protein family HMM PF03372; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1927793 xth-2 1167706 xth-2 Brucella suis 1330 exodeoxyribonuclease III NP_698979.1 1926987 D 204722 CDS NP_698980.1 23502853 1167707 complement(1927799..1928260) 1 NC_004310.3 identified by match to protein family HMM PF00027; cyclic nucleotide-binding protein 1928260 1167707 BR2005 Brucella suis 1330 cyclic nucleotide-binding protein NP_698980.1 1927799 R 204722 CDS NP_698981.1 23502854 1167708 complement(1928295..1928978) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3262; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 1928978 1167708 BR2006 Brucella suis 1330 DNA-binding response regulator NP_698981.1 1928295 R 204722 CDS NP_698982.1 23502855 1167709 1929228..1929731 1 NC_004310.3 identified by similarity to GP:14024337; hypothetical protein 1929731 1167709 BR2007 Brucella suis 1330 hypothetical protein NP_698982.1 1929228 D 204722 CDS NP_698983.1 23502856 1167710 1929792..1930091 1 NC_004310.3 hypothetical protein 1930091 1167710 BR2008 Brucella suis 1330 hypothetical protein NP_698983.1 1929792 D 204722 CDS NP_698984.1 23502857 1167711 complement(1930120..1931643) 1 NC_004310.3 intimin/invasin family protein 1931643 1167711 BR2009 Brucella suis 1330 intimin/invasin family protein NP_698984.1 1930120 R 204722 CDS NP_698985.1 23502858 1167712 complement(1931640..1932719) 1 NC_004310.3 hypothetical protein 1932719 1167712 BR2010 Brucella suis 1330 hypothetical protein NP_698985.1 1931640 R 204722 CDS NP_698986.1 23502859 1167713 1933046..1933435 1 NC_004310.3 hypothetical protein 1933435 1167713 BR2011 Brucella suis 1330 hypothetical protein NP_698986.1 1933046 D 204722 CDS NP_698987.1 23502860 1167714 complement(1933522..1935078) 1 NC_004310.3 hypothetical protein 1935078 1167714 BR2012 Brucella suis 1330 hypothetical protein NP_698987.1 1933522 R 204722 CDS NP_698988.1 23502861 1167715 1935263..1940044 1 NC_004310.3 identified by similarity to GP:15162141; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR01612; outer membrane autotransporter 1940044 1167715 BR2013 Brucella suis 1330 outer membrane autotransporter NP_698988.1 1935263 D 204722 CDS NP_698989.1 23502862 1167716 complement(1940185..1940856) 1 NC_004310.3 identified by similarity to GP:15075693; match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein 1940856 1167716 BR2014 Brucella suis 1330 hypothetical protein NP_698989.1 1940185 R 204722 CDS NP_698990.1 23502863 1167717 complement(1940936..1941229) 1 NC_004310.3 required for 70S ribosome assembly; 50S ribosomal protein L28 1941229 rpmB 1167717 rpmB Brucella suis 1330 50S ribosomal protein L28 NP_698990.1 1940936 R 204722 CDS NP_698991.1 23502864 1167718 1941591..1942406 1 NC_004310.3 identified by similarity to OMNI:NTL02ML2738; hypothetical protein 1942406 1167718 BR2016 Brucella suis 1330 hypothetical protein NP_698991.1 1941591 D 204722 CDS NP_698992.1 23502865 1167719 complement(1942518..1942940) 1 NC_004310.3 identified by match to protein family HMM PF00376; MerR family transcriptional regulator 1942940 1167719 BR2017 Brucella suis 1330 MerR family transcriptional regulator NP_698992.1 1942518 R 204722 CDS NP_698993.1 23502866 1167720 1943029..1945473 1 NC_004310.3 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-translocating P-type ATPase 1945473 cadA-1 1167720 cadA-1 Brucella suis 1330 cadmium-translocating P-type ATPase NP_698993.1 1943029 D 204722 CDS NP_698994.1 23502867 1167721 1945880..1946629 1 NC_004310.3 identified by similarity to GP:15141324; hypothetical protein 1946629 1167721 BR2019 Brucella suis 1330 hypothetical protein NP_698994.1 1945880 D 204722 CDS NP_698995.1 23502868 1167722 1946656..1947741 1 NC_004310.3 hypothetical protein 1947741 1167722 BR2020 Brucella suis 1330 hypothetical protein NP_698995.1 1946656 D 204722 CDS NP_698996.1 23502869 1167723 complement(1947914..1949815) 1 NC_004310.3 identified by similarity to SP:P29934; match to protein family HMM TIGR01651; cobalamin biosynthesis protein 1949815 1167723 BR2021 Brucella suis 1330 cobalamin biosynthesis protein NP_698996.1 1947914 R 204722 CDS NP_698997.1 23502870 1167724 complement(1949923..1950909) 1 NC_004310.3 identified by similarity to SP:P29933; match to protein family HMM TIGR01650; cobalamin biosynthesis protein 1950909 1167724 BR2022 Brucella suis 1330 cobalamin biosynthesis protein NP_698997.1 1949923 R 204722 CDS NP_698998.1 23502871 1167725 1950988..1951218 1 NC_004310.3 hypothetical protein 1951218 1167725 BR2023 Brucella suis 1330 hypothetical protein NP_698998.1 1950988 D 204722 CDS NP_698999.1 23502872 1167726 complement(1951196..1951825) 1 NC_004310.3 identified by match to protein family HMM PF00226; DnaJ domain-containing protein 1951825 1167726 BR2024 Brucella suis 1330 DnaJ domain-containing protein NP_698999.1 1951196 R 204722 CDS NP_699000.1 23502873 1167727 complement(1951822..1952019) 1 NC_004310.3 hypothetical protein 1952019 1167727 BR2025 Brucella suis 1330 hypothetical protein NP_699000.1 1951822 R 204722 CDS NP_699001.1 23502874 1167728 1952012..1952326 1 NC_004310.3 identified by similarity to SP:P15298; match to protein family HMM PF01722; bolA protein 1952326 bolA 1167728 bolA Brucella suis 1330 bolA protein NP_699001.1 1952012 D 204722 CDS NP_699002.1 23502875 1167729 complement(1952351..1953658) 1 NC_004310.3 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain-containing protein 1953658 1167729 BR2027 Brucella suis 1330 CBS domain-containing protein NP_699002.1 1952351 R 204722 CDS NP_699003.1 23502876 1167730 complement(1953722..1954858) 1 NC_004310.3 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 1954858 aroB 1167730 aroB Brucella suis 1330 3-dehydroquinate synthase NP_699003.1 1953722 R 204722 CDS NP_699004.1 23502877 1167731 complement(1954951..1955553) 1 NC_004310.3 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 1955553 aroK 1167731 aroK Brucella suis 1330 shikimate kinase NP_699004.1 1954951 R 204722 CDS NP_699005.1 23502878 1167732 1955678..1955884 1 NC_004310.3 hypothetical protein 1955884 1167732 BR2030 Brucella suis 1330 hypothetical protein NP_699005.1 1955678 D 204722 CDS NP_699006.1 23502879 1167733 1955887..1956810 1 NC_004310.3 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1956810 xerD 1167733 xerD Brucella suis 1330 site-specific tyrosine recombinase XerD NP_699006.1 1955887 D 204722 CDS NP_699007.1 23502880 1167734 1956949..1957902 1 NC_004310.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1957902 accA 1167734 accA Brucella suis 1330 acetyl-CoA carboxylase carboxyltransferase subunit alpha NP_699007.1 1956949 D 204722 CDS NP_699008.1 23502881 1167735 1958124..1959335 1 NC_004310.3 identified by similarity to GP:15159690; lipoprotein 1959335 1167735 BR2033 Brucella suis 1330 lipoprotein NP_699008.1 1958124 D 204722 CDS NP_699009.1 23502882 1167736 1959314..1959571 1 NC_004310.3 identified by similarity to GP:15075708; match to protein family HMM PF01206; hypothetical protein 1959571 1167736 BR2034 Brucella suis 1330 hypothetical protein NP_699009.1 1959314 D 204722 CDS NP_699010.1 23502883 1167737 complement(1959589..1960761) 1 NC_004310.3 identified by match to protein family HMM PF02492; cobalamin synthesis protein/P47K family protein 1960761 1167737 BR2035 Brucella suis 1330 cobalamin synthesis protein/P47K family protein NP_699010.1 1959589 R 204722 CDS NP_699011.1 23502884 1167738 complement(1960763..1961878) 1 NC_004310.3 identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1961878 1167738 BR2036 Brucella suis 1330 D-alanyl-D-alanine carboxypeptidase NP_699011.1 1960763 R 204722 CDS NP_699012.1 23502885 1167739 1962173..1963336 1 NC_004310.3 identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 1963336 1167739 BR2037 Brucella suis 1330 M20/M25/M40 family peptidase NP_699012.1 1962173 D 204722 CDS NP_699013.1 23502886 1167740 1963333..1963467 1 NC_004310.3 hypothetical protein 1963467 1167740 BR2038 Brucella suis 1330 hypothetical protein NP_699013.1 1963333 D 204722 CDS NP_699014.1 23502887 1167742 complement(1963535..1964299) 1 NC_004310.3 identified by similarity to EGAD:23256; match to protein family HMM PF00106; glucose 1-dehydrogenase 1964299 1167742 BR2039 Brucella suis 1330 glucose 1-dehydrogenase NP_699014.1 1963535 R 204722 CDS NP_699015.1 23502888 1167743 1964407..1964841 1 NC_004310.3 identified by similarity to GP:15157579; match to protein family HMM PF04828; hypothetical protein 1964841 1167743 BR2040 Brucella suis 1330 hypothetical protein NP_699015.1 1964407 D 204722 CDS NP_699016.1 23502889 1167744 1964991..1965335 1 NC_004310.3 identified by similarity to OMNI:NTL03PA01934; hypothetical protein 1965335 1167744 BR2041 Brucella suis 1330 hypothetical protein NP_699016.1 1964991 D 204722 CDS NP_699017.1 23502890 1167745 complement(1965405..1967039) 1 NC_004310.3 identified by similarity to EGAD:149670; match to protein family HMM PF00732; match to protein family HMM PF05199; L-sorbose dehydrogenase 1967039 1167745 BR2042 Brucella suis 1330 L-sorbose dehydrogenase NP_699017.1 1965405 R 204722 CDS NP_699018.1 23502891 1167746 complement(1967050..1967814) 1 NC_004310.3 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1967814 fabG 1167746 fabG Brucella suis 1330 3-ketoacyl-ACP reductase NP_699018.1 1967050 R 204722 CDS NP_699019.1 23502892 1167747 complement(1967811..1969295) 1 NC_004310.3 GMC family oxidoreductase 1969295 1167747 BR2044 Brucella suis 1330 GMC family oxidoreductase NP_699019.1 1967811 R 204722 CDS NP_699020.1 23502893 1167748 complement(1969308..1970828) 1 NC_004310.3 identified by similarity to EGAD:149672; match to protein family HMM PF00171; L-sorbosone dehydrogenase, NAD(P) dependent 1970828 1167748 BR2045 Brucella suis 1330 L-sorbosone dehydrogenase, NAD(P) dependent NP_699020.1 1969308 R 204722 CDS NP_699021.1 23502894 1167749 complement(1970822..1971598) 1 NC_004310.3 identified by match to protein family HMM PF00378; enoyl-CoA hydratase 1971598 1167749 BR2046 Brucella suis 1330 enoyl-CoA hydratase NP_699021.1 1970822 R 204722 CDS NP_699022.1 23502895 1167750 complement(1971600..1973201) 1 NC_004310.3 identified by match to protein family HMM PF01144; acetyl-CoA-transferase subunit 1973201 1167750 BR2047 Brucella suis 1330 acetyl-CoA-transferase subunit NP_699022.1 1971600 R 204722 CDS NP_699023.1 23502896 1167751 complement(1973207..1974208) 1 NC_004310.3 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 1974208 1167751 BR2048 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699023.1 1973207 R 204722 CDS NP_699024.1 23502897 1167752 complement(1974187..1975245) 1 NC_004310.3 identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcription regulator 1975245 1167752 BR2049 Brucella suis 1330 LacI family transcription regulator NP_699024.1 1974187 R 204722 CDS NP_699025.1 23502898 1167753 1975496..1976665 1 NC_004310.3 identified by similarity to GP:15076333; hypothetical protein 1976665 1167753 BR2050 Brucella suis 1330 hypothetical protein NP_699025.1 1975496 D 204722 CDS NP_699026.1 23502899 1167754 complement(1976699..1977721) 1 NC_004310.3 identified by match to protein family HMM PF00296; luciferase 1977721 1167754 BR2051 Brucella suis 1330 luciferase NP_699026.1 1976699 R 204722 CDS NP_699027.1 23502900 1167755 complement(1977718..1977927) 1 NC_004310.3 hypothetical protein 1977927 1167755 BR2052 Brucella suis 1330 hypothetical protein NP_699027.1 1977718 R 204722 CDS NP_699028.1 23502901 1167756 1977990..1978955 1 NC_004310.3 identified by similarity to GP:15076239; match to protein family HMM PF04392; ABC transporter periplasmic substrate-binding protein 1978955 1167756 BR2053 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_699028.1 1977990 D 204722 CDS NP_699029.1 23502902 1167757 complement(1979159..1979419) 1 NC_004310.3 hypothetical protein 1979419 1167757 BR2054 Brucella suis 1330 hypothetical protein NP_699029.1 1979159 R 204722 CDS NP_699030.1 23502903 1167758 1979599..1980483 1 NC_004310.3 identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1980483 1167758 BR2055 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699030.1 1979599 D 204722 CDS NP_699031.1 23502904 1167759 1980480..1981274 1 NC_004310.3 identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1981274 1167759 BR2056 Brucella suis 1330 ABC transporter ATP-binding protein NP_699031.1 1980480 D 204722 CDS NP_699032.1 23502905 1167760 1981436..1982479 1 NC_004310.3 required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1982479 holA 1167760 holA Brucella suis 1330 DNA polymerase III subunit delta NP_699032.1 1981436 D 204722 CDS NP_699033.1 23502906 1167761 complement(1982573..1983454) 1 NC_004310.3 identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; chromosome partitioning protein ParB 1983454 parB 1167761 parB Brucella suis 1330 chromosome partitioning protein ParB NP_699033.1 1982573 R 204722 CDS NP_699034.1 23502907 1167762 complement(1983498..1984295) 1 NC_004310.3 identified by similarity to SP:O05189; match to protein family HMM PF00991; chromosome partitioning protein ParA 1984295 parA 1167762 parA Brucella suis 1330 chromosome partitioning protein ParA NP_699034.1 1983498 R 204722 CDS NP_699035.1 23502908 1167763 complement(1984348..1984989) 1 NC_004310.3 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1984989 gidB 1167763 gidB Brucella suis 1330 16S rRNA methyltransferase GidB NP_699035.1 1984348 R 204722 CDS NP_699036.1 23502909 1167764 complement(1984986..1986896) 1 NC_004310.3 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 1986896 gidA 1167764 gidA Brucella suis 1330 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA NP_699036.1 1984986 R 204722 CDS NP_699037.1 23502910 1167765 complement(1987123..1988451) 1 NC_004310.3 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1988451 trmE 1167765 trmE Brucella suis 1330 tRNA modification GTPase TrmE NP_699037.1 1987123 R 204722 CDS NP_699038.1 23502911 1167766 1988566..1990566 1 NC_004310.3 identified by similarity to GP:14024528; match to protein family HMM PF03190; hypothetical protein 1990566 1167766 BR2063 Brucella suis 1330 hypothetical protein NP_699038.1 1988566 D 204722 CDS NP_699039.1 23502912 1167767 complement(1990651..1991916) 1 NC_004310.3 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 1991916 rho 1167767 rho Brucella suis 1330 transcription termination factor Rho NP_699039.1 1990651 R 204722 CDS NP_699040.1 23502913 1167768 complement(1992298..1992834) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3455; match to protein family HMM PF03653; match to protein family HMM TIGR00701; hypothetical protein 1992834 1167768 BR2065 Brucella suis 1330 hypothetical protein NP_699040.1 1992298 R 204722 CDS NP_699041.1 23502914 1167769 complement(1992831..1993856) 1 NC_004310.3 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1993856 hemE 1167769 hemE Brucella suis 1330 uroporphyrinogen decarboxylase NP_699041.1 1992831 R 204722 CDS NP_699042.1 23502915 1167770 1994309..1995148 1 NC_004310.3 identified by similarity to GP:14024532; match to protein family HMM PF03618; hypothetical protein 1995148 1167770 BR2067 Brucella suis 1330 hypothetical protein NP_699042.1 1994309 D 204722 CDS NP_699043.1 23502916 1167771 1995145..1995744 1 NC_004310.3 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1995744 maf 1167771 maf Brucella suis 1330 Maf-like protein NP_699043.1 1995145 D 204722 CDS NP_699044.1 23502917 1167772 1995752..1996606 1 NC_004310.3 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1996606 aroE 1167772 aroE Brucella suis 1330 shikimate 5-dehydrogenase NP_699044.1 1995752 D 204722 CDS NP_699045.1 23502918 1167773 1996603..1997205 1 NC_004310.3 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1997205 coaE 1167773 coaE Brucella suis 1330 dephospho-CoA kinase NP_699045.1 1996603 D 204722 CDS NP_699046.1 23502919 1167774 1997247..1997951 1 NC_004310.3 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1997951 dnaQ 1167774 dnaQ Brucella suis 1330 DNA polymerase III subunit epsilon NP_699046.1 1997247 D 204722 CDS NP_699047.1 23502920 1167775 complement(1998010..1998501) 1 NC_004310.3 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 1998501 secB 1167775 secB Brucella suis 1330 preprotein translocase subunit SecB NP_699047.1 1998010 R 204722 CDS NP_699048.1 23502921 1167776 complement(1998621..1999118) 1 NC_004310.3 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA 1999118 fxsA 1167776 fxsA Brucella suis 1330 FxsA NP_699048.1 1998621 R 204722 CDS NP_699049.1 23502922 1167777 1999323..2000030 1 NC_004310.3 identified by similarity to GP:15154866; hypothetical protein 2000030 1167777 BR2074 Brucella suis 1330 hypothetical protein NP_699049.1 1999323 D 204722 CDS NP_699050.1 23502923 1167778 2000094..2001203 1 NC_004310.3 identified by match to protein family HMM PF03562; transglycosylase-like protein 2001203 1167778 BR2075 Brucella suis 1330 transglycosylase-like protein NP_699050.1 2000094 D 204722 CDS NP_699051.1 23502924 1167779 2001209..2001811 1 NC_004310.3 identified by match to protein family HMM PF01713; Smr family protein 2001811 1167779 BR2076 Brucella suis 1330 Smr family protein NP_699051.1 2001209 D 204722 CDS NP_699052.1 23502925 1167780 2001808..2002188 1 NC_004310.3 identified by similarity to GP:15154869; match to protein family HMM PF01381; hypothetical protein 2002188 1167780 BR2077 Brucella suis 1330 hypothetical protein NP_699052.1 2001808 D 204722 CDS NP_699053.1 23502926 1167781 complement(2002197..2003126) 1 NC_004310.3 identified by similarity to GP:15154911; hypothetical protein 2003126 1167781 BR2078 Brucella suis 1330 hypothetical protein NP_699053.1 2002197 R 204722 CDS NP_699054.1 23502927 1167782 complement(2003363..2004667) 1 NC_004310.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 2004667 hslU 1167782 hslU Brucella suis 1330 ATP-dependent protease ATP-binding subunit HslU NP_699054.1 2003363 R 204722 CDS NP_699055.1 23502928 1167783 complement(2004741..2005295) 1 NC_004310.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 2005295 hslV 1167783 hslV Brucella suis 1330 ATP-dependent protease peptidase subunit NP_699055.1 2004741 R 204722 CDS NP_699056.1 23502929 1167784 2005592..2006200 1 NC_004310.3 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2006200 hisB 1167784 hisB Brucella suis 1330 imidazoleglycerol-phosphate dehydratase NP_699056.1 2005592 D 204722 CDS NP_699057.1 23502930 1167785 2006312..2006821 1 NC_004310.3 identified by similarity to GP:15072982; hypothetical protein 2006821 1167785 BR2082 Brucella suis 1330 hypothetical protein NP_699057.1 2006312 D 204722 CDS NP_699058.1 23502931 1167786 2006824..2007474 1 NC_004310.3 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2007474 hisH 1167786 hisH Brucella suis 1330 imidazole glycerol phosphate synthase subunit HisH NP_699058.1 2006824 D 204722 CDS NP_699059.1 23502932 1167787 2007479..2008210 1 NC_004310.3 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2008210 hisA 1167787 hisA Brucella suis 1330 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NP_699059.1 2007479 D 204722 CDS NP_699060.1 23502933 1167788 2008207..2008992 1 NC_004310.3 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2008992 hisF 1167788 hisF Brucella suis 1330 imidazole glycerol phosphate synthase subunit HisF NP_699060.1 2008207 D 204722 CDS NP_699061.1 23502934 1167789 2009128..2009451 1 NC_004310.3 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2009451 hisE 1167789 hisE Brucella suis 1330 phosphoribosyl-ATP pyrophosphatase NP_699061.1 2009128 D 204722 CDS NP_699062.1 23502935 1167790 2009466..2010434 1 NC_004310.3 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2010434 coaA 1167790 coaA Brucella suis 1330 pantothenate kinase NP_699062.1 2009466 D 204722 CDS NP_699063.1 23502936 1167791 complement(2010497..2011033) 1 NC_004310.3 identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein 2011033 1167791 BR2088 Brucella suis 1330 peptidyl-tRNA hydrolase domain-containing protein NP_699063.1 2010497 R 204722 CDS NP_699064.1 23502937 1167792 complement(2011046..2012656) 1 NC_004310.3 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 2012656 pckA 1167792 pckA Brucella suis 1330 phosphoenolpyruvate carboxykinase NP_699064.1 2011046 R 204722 CDS NP_699065.1 23502938 1167793 2013059..2013778 1 NC_004310.3 identified by similarity to GP:2947107; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator BvrR 2013778 1167793 BR2090 Brucella suis 1330 DNA-binding response regulator BvrR NP_699065.1 2013059 D 204722 CDS NP_699066.1 23502939 1167794 2013889..2015694 1 NC_004310.3 identified by similarity to GP:2947211; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase BvrS 2015694 1167794 BR2091 Brucella suis 1330 sensor histidine kinase BvrS NP_699066.1 2013889 D 204722 CDS NP_699067.1 23502940 1167795 2015720..2016199 1 NC_004310.3 identified by similarity to GP:14024999; hypothetical protein 2016199 1167795 BR2092 Brucella suis 1330 hypothetical protein NP_699067.1 2015720 D 204722 CDS NP_699068.1 23502941 1167796 2016174..2016449 1 NC_004310.3 hypothetical protein 2016449 1167796 BR2093 Brucella suis 1330 hypothetical protein NP_699068.1 2016174 D 204722 CDS NP_699069.1 23502942 1167797 2016451..2016852 1 NC_004310.3 identified by similarity to EGAD:7066; match to protein family HMM PF03610; PTS system, IIA component 2016852 1167797 BR2094 Brucella suis 1330 PTS system, IIA component NP_699069.1 2016451 D 204722 CDS NP_699070.1 23502943 1167798 2016856..2017170 1 NC_004310.3 identified by similarity to SP:P08877; match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 2017170 ptsH 1167798 ptsH Brucella suis 1330 phosphocarrier protein HPr NP_699070.1 2016856 D 204722 CDS NP_699071.1 23502944 1167799 2017234..2017551 1 NC_004310.3 hypothetical protein 2017551 1167799 BR2096 Brucella suis 1330 hypothetical protein NP_699071.1 2017234 D 204722 CDS NP_699072.1 23502945 1167800 2017548..2018948 1 NC_004310.3 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2018948 ahcY 1167800 ahcY Brucella suis 1330 S-adenosyl-L-homocysteine hydrolase NP_699072.1 2017548 D 204722 CDS NP_699073.1 23502946 1167801 2019136..2019345 1 NC_004310.3 hypothetical protein 2019345 1167801 BR2098 Brucella suis 1330 hypothetical protein NP_699073.1 2019136 D 204722 CDS NP_699074.1 23502947 1167802 2019333..2021912 1 NC_004310.3 identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 2021912 1167802 BR2099 Brucella suis 1330 sensory box histidine kinase NP_699074.1 2019333 D 204722 CDS NP_699075.1 23502948 1167803 2021921..2023462 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3919; match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 2023462 1167803 BR2100 Brucella suis 1330 hypothetical protein NP_699075.1 2021921 D 204722 CDS NP_699076.1 23502949 1167804 2023449..2024168 1 NC_004310.3 identified by similarity to GP:14024993; match to protein family HMM PF00483; nucleotidyltransferase 2024168 1167804 BR2101 Brucella suis 1330 nucleotidyltransferase NP_699076.1 2023449 D 204722 CDS NP_699077.1 23502950 1167805 2024183..2027341 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3917; hypothetical protein 2027341 1167805 BR2102 Brucella suis 1330 hypothetical protein NP_699077.1 2024183 D 204722 CDS NP_699078.1 23502951 1167806 2027338..2030880 1 NC_004310.3 identified by similarity to OMNI:CC3538; match to protein family HMM PF00580; UvrD/REP helicase 2030880 1167806 BR2103 Brucella suis 1330 UvrD/REP helicase NP_699078.1 2027338 D 204722 CDS NP_699079.1 23502952 1167807 2030858..2030995 1 NC_004310.3 hypothetical protein 2030995 1167807 BR2104 Brucella suis 1330 hypothetical protein NP_699079.1 2030858 D 204722 CDS NP_699080.1 23502953 1167808 2031062..2031385 1 NC_004310.3 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2031385 trx-1 1167808 trx-1 Brucella suis 1330 thioredoxin NP_699080.1 2031062 D 204722 CDS NP_699081.1 23502954 1167809 complement(2031599..2032927) 1 NC_004310.3 identified by match to protein family HMM TIGR01499; FolC bifunctional protein 2032927 folC 1167809 folC Brucella suis 1330 FolC bifunctional protein NP_699081.1 2031599 R 204722 CDS NP_699082.1 23502955 1167810 complement(2032930..2033835) 1 NC_004310.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 2033835 accD 1167810 accD Brucella suis 1330 acetyl-CoA carboxylase subunit beta NP_699082.1 2032930 R 204722 CDS NP_699083.1 23502956 1167811 complement(2033896..2034735) 1 NC_004310.3 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 2034735 trpA 1167811 trpA Brucella suis 1330 tryptophan synthase subunit alpha NP_699083.1 2033896 R 204722 CDS NP_699084.1 23502957 1167812 complement(2034732..2035079) 1 NC_004310.3 hypothetical protein 2035079 1167812 BR2109 Brucella suis 1330 hypothetical protein NP_699084.1 2034732 R 204722 CDS NP_699085.1 23502958 1167813 complement(2035202..2036422) 1 NC_004310.3 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 2036422 trpB 1167813 trpB Brucella suis 1330 tryptophan synthase subunit beta NP_699085.1 2035202 R 204722 CDS NP_699086.1 23502959 1167814 complement(2036442..2037110) 1 NC_004310.3 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 2037110 trpF 1167814 trpF Brucella suis 1330 N-(5'-phosphoribosyl)anthranilate isomerase NP_699086.1 2036442 R 204722 CDS NP_699087.1 23502960 1167815 complement(2037149..2037784) 1 NC_004310.3 identified by similarity to OMNI:VC1698; hypothetical protein 2037784 1167815 BR2112 Brucella suis 1330 hypothetical protein NP_699087.1 2037149 R 204722 CDS NP_699088.1 23502961 1167816 complement(2037781..2038542) 1 NC_004310.3 identified by similarity to GP:15154876; match to protein family HMM PF01863; hypothetical protein 2038542 1167816 BR2113 Brucella suis 1330 hypothetical protein NP_699088.1 2037781 R 204722 CDS NP_699089.1 23502962 1167817 complement(2038651..2039097) 1 NC_004310.3 identified by similarity to GP:15072953; hypothetical protein 2039097 1167817 BR2114 Brucella suis 1330 hypothetical protein NP_699089.1 2038651 R 204722 CDS NP_699090.1 23502963 1167818 complement(2039279..2040430) 1 NC_004310.3 identified by match to protein family HMM PF03594; match to protein family HMM TIGR00843; benzoate transport protein 2040430 1167818 BR2115 Brucella suis 1330 benzoate transport protein NP_699090.1 2039279 R 204722 CDS NP_699091.1 23502964 1167819 complement(2040444..2041235) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3900; hypothetical protein 2041235 1167819 BR2116 Brucella suis 1330 hypothetical protein NP_699091.1 2040444 R 204722 CDS NP_699092.1 23502965 1167820 2041667..2042071 1 NC_004310.3 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2042071 infC 1167820 infC Brucella suis 1330 translation initiation factor IF-3 NP_699092.1 2041667 D 204722 CDS NP_699093.1 23502966 1167821 2042200..2042814 1 NC_004310.3 identified by similarity to EGAD:42737; nickel-cobalt-cadmium resistance protein 2042814 1167821 BR2118 Brucella suis 1330 nickel-cobalt-cadmium resistance protein NP_699093.1 2042200 D 204722 CDS NP_699094.1 23502967 1167822 2043081..2043281 1 NC_004310.3 identified by similarity to SP:P55874; match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 2043281 rpmI 1167822 rpmI Brucella suis 1330 50S ribosomal protein L35 NP_699094.1 2043081 D 204722 CDS NP_699095.1 23502968 1167823 2043309..2043713 1 NC_004310.3 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2043713 rplT 1167823 rplT Brucella suis 1330 50S ribosomal protein L20 NP_699095.1 2043309 D 204722 CDS NP_699096.1 23502969 1167824 2043812..2044654 1 NC_004310.3 identified by similarity to GP:15155150; hypothetical protein 2044654 1167824 BR2121 Brucella suis 1330 hypothetical protein NP_699096.1 2043812 D 204722 CDS NP_699097.1 23502970 1167825 2044743..2045852 1 NC_004310.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2045852 pheS 1167825 pheS Brucella suis 1330 phenylalanyl-tRNA synthetase subunit alpha NP_699097.1 2044743 D 204722 CDS NP_699098.1 23502971 1167826 2045874..2048288 1 NC_004310.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2048288 pheT 1167826 pheT Brucella suis 1330 phenylalanyl-tRNA synthetase subunit beta NP_699098.1 2045874 D 204722 CDS NP_699099.1 23502972 1167827 2048358..2049344 1 NC_004310.3 identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 2049344 1167827 BR2124 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699099.1 2048358 D 204722 CDS NP_699100.1 23502973 1167828 2049570..2051483 1 NC_004310.3 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2051483 dnaK 1167828 dnaK Brucella suis 1330 molecular chaperone DnaK NP_699100.1 2049570 D 204722 CDS NP_699101.1 23502974 1167829 2051728..2052861 1 NC_004310.3 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 2052861 dnaJ 1167829 dnaJ Brucella suis 1330 molecular chaperone DnaJ NP_699101.1 2051728 D 204722 CDS NP_699102.1 23502975 1167830 2052982..2053578 1 NC_004310.3 identified by similarity to GP:9966391; phospholipid N-methyltransferase 2053578 pmtA 1167830 pmtA Brucella suis 1330 phospholipid N-methyltransferase NP_699102.1 2052982 D 204722 CDS NP_699103.1 23502976 1167831 2053788..2054504 1 NC_004310.3 OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2054504 pyrF 1167831 pyrF Brucella suis 1330 orotidine 5'-phosphate decarboxylase NP_699103.1 2053788 D 204722 CDS NP_699104.1 23502977 1167832 2054553..2054840 1 NC_004310.3 identified by similarity to GP:15155195; hypothetical protein 2054840 1167832 BR2129 Brucella suis 1330 hypothetical protein NP_699104.1 2054553 D 204722 CDS NP_699105.1 23502978 1167833 complement(2054878..2056065) 1 NC_004310.3 identified by similarity to OMNI:NTL02ML3653; match to protein family HMM PF03758; Smp-30/Cgr1 family protein 2056065 1167833 BR2130 Brucella suis 1330 Smp-30/Cgr1 family protein NP_699105.1 2054878 R 204722 CDS NP_699106.1 23502979 1167834 2056001..2056939 1 NC_004310.3 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2056939 gshb 1167834 gshb Brucella suis 1330 glutathione synthetase NP_699106.1 2056001 D 204722 CDS NP_699107.1 23502980 1167835 2057049..2058581 1 NC_004310.3 identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368; Mg chelatase-like protein 2058581 1167835 BR2132 Brucella suis 1330 Mg chelatase-like protein NP_699107.1 2057049 D 204722 CDS NP_699108.1 23502981 1167836 complement(2058630..2059250) 1 NC_004310.3 identified by similarity to GP:15074346; hypothetical protein 2059250 1167836 BR2133 Brucella suis 1330 hypothetical protein NP_699108.1 2058630 R 204722 CDS NP_699109.1 23502982 1167837 2059511..2059624 1 NC_004310.3 hypothetical protein 2059624 1167837 BR2134 Brucella suis 1330 hypothetical protein NP_699109.1 2059511 D 204722 CDS NP_699110.1 23502983 1167838 complement(2059697..2060053) 1 NC_004310.3 identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein 2060053 1167838 BR2135 Brucella suis 1330 rare lipoprotein A family protein NP_699110.1 2059697 R 204722 CDS NP_699111.1 23502984 1167839 2060209..2060430 1 NC_004310.3 hypothetical protein 2060430 1167839 BR2136 Brucella suis 1330 hypothetical protein NP_699111.1 2060209 D 204722 CDS NP_699112.1 23502985 1167840 2060663..2061013 1 NC_004310.3 identified by similarity to EGAD:35582; hypothetical protein 2061013 1167840 BR2137 Brucella suis 1330 hypothetical protein NP_699112.1 2060663 D 204722 CDS NP_699113.1 23502986 1167841 2061168..2062214 1 NC_004310.3 phosphate ABC transporter phosphate-binding protein 2062214 1167841 BR2138 Brucella suis 1330 phosphate ABC transporter phosphate-binding protein NP_699113.1 2061168 D 204722 CDS NP_699114.1 23502987 1167842 2062356..2063846 1 NC_004310.3 identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 2063846 pstC 1167842 pstC Brucella suis 1330 phosphate ABC transporter permease NP_699114.1 2062356 D 204722 CDS NP_699115.1 23502988 1167843 2063846..2065156 1 NC_004310.3 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 2065156 1167843 BR2140 Brucella suis 1330 phosphate ABC transporter permease NP_699115.1 2063846 D 204722 CDS NP_699116.1 23502989 1167844 2065221..2065994 1 NC_004310.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2065994 pstB 1167844 pstB Brucella suis 1330 phosphate transporter ATP-binding protein NP_699116.1 2065221 D 204722 CDS NP_699117.1 23502990 1167845 2066060..2066782 1 NC_004310.3 identified by similarity to EGAD:14202; match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 2066782 phoU 1167845 phoU Brucella suis 1330 phosphate transport system regulatory protein PhoU NP_699117.1 2066060 D 204722 CDS NP_699118.1 23502991 1167846 2066900..2067586 1 NC_004310.3 identified by similarity to EGAD:5895; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR02154; phosphate regulon transcriptional regulatory protein Phob 2067586 phoB 1167846 phoB Brucella suis 1330 phosphate regulon transcriptional regulatory protein Phob NP_699118.1 2066900 D 204722 CDS NP_699119.1 23502992 1167847 complement(2067942..2068100) 1 NC_004310.3 hypothetical protein 2068100 1167847 BR2144 Brucella suis 1330 hypothetical protein NP_699119.1 2067942 R 204722 CDS NP_699120.1 23502993 1167848 2068172..2069152 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4270; lipoprotein 2069152 1167848 BR2145 Brucella suis 1330 lipoprotein NP_699120.1 2068172 D 204722 CDS NP_699121.1 23502994 1167849 complement(2069262..2069585) 1 NC_004310.3 identified by similarity to GP:15155785; lipoprotein 2069585 1167849 BR2146 Brucella suis 1330 lipoprotein NP_699121.1 2069262 R 204722 CDS NP_699122.1 23502995 1167850 complement(2069575..2069679) 1 NC_004310.3 hypothetical protein 2069679 1167850 BR2147 Brucella suis 1330 hypothetical protein NP_699122.1 2069575 R 204722 CDS NP_699123.1 23502996 1167851 2069662..2070915 1 NC_004310.3 identified by similarity to SP:Q9X4A7; match to protein family HMM PF02073; aminopeptidase 2070915 pepS 1167851 pepS Brucella suis 1330 aminopeptidase NP_699123.1 2069662 D 204722 CDS NP_699124.1 23502997 1167852 complement(2071076..2071573) 1 NC_004310.3 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps 2071573 1167852 BR2149 Brucella suis 1330 DNA starvation/stationary phase protection protein Dps NP_699124.1 2071076 R 204722 CDS NP_699125.1 23502998 1167853 2071760..2072545 1 NC_004310.3 identified by match to protein family HMM PF00814; protease 2072545 1167853 BR2150 Brucella suis 1330 protease NP_699125.1 2071760 D 204722 CDS NP_699126.1 23502999 1167854 2072550..2073050 1 NC_004310.3 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; acetyltransferase 2073050 1167854 BR2151 Brucella suis 1330 acetyltransferase NP_699126.1 2072550 D 204722 CDS NP_699127.1 23503000 1167855 2073047..2073850 1 NC_004310.3 identified by match to protein family HMM PF01553; acyltransferase 2073850 1167855 BR2152 Brucella suis 1330 acyltransferase NP_699127.1 2073047 D 204722 CDS NP_699128.1 23503001 1167856 2073908..2075311 1 NC_004310.3 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2075311 1167856 BR2153 Brucella suis 1330 (dimethylallyl)adenosine tRNA methylthiotransferase NP_699128.1 2073908 D 204722 CDS NP_699129.1 23503002 1167857 complement(2075409..2075501) 1 NC_004310.3 hypothetical protein 2075501 1167857 BR2154 Brucella suis 1330 hypothetical protein NP_699129.1 2075409 R 204722 CDS NP_699130.1 23503003 1167858 2075548..2076531 1 NC_004310.3 identified by match to protein family HMM PF02562; PhoH family protein 2076531 1167858 BR2155 Brucella suis 1330 PhoH family protein NP_699130.1 2075548 D 204722 CDS NP_699131.1 23503004 1167859 2076697..2077173 1 NC_004310.3 identified by similarity to OMNI:NTL02ML4294; match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein 2077173 1167859 BR2156 Brucella suis 1330 hypothetical protein NP_699131.1 2076697 D 204722 CDS NP_699132.1 23503005 1167860 2077266..2078294 1 NC_004310.3 identified by similarity to OMNI:VC0959; match to protein family HMM PF00571; match to protein family HMM PF03471; CBS domain-containing protein 2078294 1167860 BR2157 Brucella suis 1330 CBS domain-containing protein NP_699132.1 2077266 D 204722 CDS NP_699133.1 23503006 1167861 2078291..2079889 1 NC_004310.3 Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2079889 lnt 1167861 lnt Brucella suis 1330 apolipoprotein N-acyltransferase NP_699133.1 2078291 D 204722 CDS NP_699134.1 23503007 1167862 2080036..2080449 1 NC_004310.3 identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 2080449 1167862 BR2159 Brucella suis 1330 Cro/CI family transcriptional regulator NP_699134.1 2080036 D 204722 CDS NP_699135.1 23503008 1167863 2080676..2081941 1 NC_004310.3 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2081941 metK 1167863 metK Brucella suis 1330 S-adenosylmethionine synthetase NP_699135.1 2080676 D 204722 CDS NP_699136.1 23503009 1167864 2081950..2082651 1 NC_004310.3 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2082651 trmB 1167864 trmB Brucella suis 1330 tRNA (guanine-N(7)-)-methyltransferase NP_699136.1 2081950 D 204722 CDS NP_699137.1 23503010 1167865 2082831..2083490 1 NC_004310.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2083490 1167865 BR2162 Brucella suis 1330 hypothetical protein NP_699137.1 2082831 D 204722 CDS NP_699138.1 23503011 1167866 2083543..2085156 1 NC_004310.3 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2085156 nusA 1167866 nusA Brucella suis 1330 transcription elongation factor NusA NP_699138.1 2083543 D 204722 CDS NP_699139.1 23503012 1167867 2085538..2086140 1 NC_004310.3 identified by similarity to GP:15073167; match to protein family HMM PF04296; hypothetical protein 2086140 1167867 BR2164 Brucella suis 1330 hypothetical protein NP_699139.1 2085538 D 204722 CDS NP_699140.1 23503013 1167868 2086278..2089157 1 NC_004310.3 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2089157 infB 1167868 infB Brucella suis 1330 translation initiation factor IF-2 NP_699140.1 2086278 D 204722 CDS NP_699141.1 23503014 1167869 2089423..2089875 1 NC_004310.3 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2089875 rbfA 1167869 rbfA Brucella suis 1330 ribosome-binding factor A NP_699141.1 2089423 D 204722 CDS YP_089635.1 52430463 1167870 2089879..2090853 1 NC_004310.3 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2090853 truB 1167870 truB Brucella suis 1330 tRNA pseudouridine synthase B YP_089635.1 2089879 D 204722 CDS NP_699142.1 23503015 1167871 2091024..2091293 1 NC_004310.3 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2091293 rpsO 1167871 rpsO Brucella suis 1330 30S ribosomal protein S15 NP_699142.1 2091024 D 204722 CDS NP_699143.1 23503016 1167872 2091577..2093721 1 NC_004310.3 identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase 2093721 pnp 1167872 pnp Brucella suis 1330 polynucleotide phosphorylase NP_699143.1 2091577 D 204722 CDS NP_699144.1 23503017 1167873 2093832..2094854 1 NC_004310.3 identified by match to protein family HMM PF05175; methyltransferase 2094854 1167873 BR2170 Brucella suis 1330 methyltransferase NP_699144.1 2093832 D 204722 CDS NP_699145.1 23503018 1167874 complement(2094902..2095720) 1 NC_004310.3 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 2095720 fabI-2 1167874 fabI-2 Brucella suis 1330 enoyl-ACP reductase NP_699145.1 2094902 R 204722 CDS NP_699146.1 23503019 1167875 complement(2095735..2096958) 1 NC_004310.3 FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 2096958 fabB 1167875 fabB Brucella suis 1330 3-oxoacyl-ACP synthase NP_699146.1 2095735 R 204722 CDS NP_699147.1 23503020 1167876 complement(2097124..2097642) 1 NC_004310.3 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase 2097642 fabA 1167876 fabA Brucella suis 1330 3-hydroxydecanoyl-ACP dehydratase NP_699147.1 2097124 R 204722 CDS NP_699148.1 23503021 1167877 2097889..2098332 1 NC_004310.3 identified by match to protein family HMM PF01475; ferric uptake regulator family protein 2098332 1167877 BR2174 Brucella suis 1330 ferric uptake regulator family protein NP_699148.1 2097889 D 204722 CDS NP_699149.1 23503022 1167878 2098498..2099277 1 NC_004310.3 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; YaeC family lipoprotein 2099277 1167878 BR2175 Brucella suis 1330 YaeC family lipoprotein NP_699149.1 2098498 D 204722 CDS NP_699150.1 23503023 1167879 complement(2099322..2099867) 1 NC_004310.3 identified by similarity to GP:14025396; hypothetical protein 2099867 1167879 BR2176 Brucella suis 1330 hypothetical protein NP_699150.1 2099322 R 204722 CDS NP_699151.1 23503024 1167880 2100218..2101222 1 NC_004310.3 Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 2101222 1167880 BR2177 Brucella suis 1330 2-hydroxyacid dehydrogenase NP_699151.1 2100218 D 204722 CDS NP_699152.1 23503025 1167881 complement(2101247..2101948) 1 NC_004310.3 hydrolase 2101948 1167881 BR2178 Brucella suis 1330 hydrolase NP_699152.1 2101247 R 204722 CDS NP_699153.1 23503026 1167882 complement(2101970..2102842) 1 NC_004310.3 identified by match to protein family HMM PF00877; NLP/P60 family protein 2102842 1167882 BR2179 Brucella suis 1330 NLP/P60 family protein NP_699153.1 2101970 R 204722 CDS NP_699154.1 23503027 1167883 complement(2102839..2103189) 1 NC_004310.3 identified by similarity to GP:15073078; transcriptional regulator 2103189 1167883 BR2180 Brucella suis 1330 transcriptional regulator NP_699154.1 2102839 R 204722 CDS NP_699155.1 23503028 1167884 complement(2103264..2104646) 1 NC_004310.3 identified by match to protein family HMM PF00883; cytosol aminopeptidase 2104646 1167884 BR2181 Brucella suis 1330 cytosol aminopeptidase NP_699155.1 2103264 R 204722 CDS NP_699156.1 23503029 1167885 complement(2104806..2104985) 1 NC_004310.3 identified by similarity to OMNI:CC2948; pilus biosynthesis protein-like protein 2104985 1167885 BR2182 Brucella suis 1330 pilus biosynthesis protein-like protein NP_699156.1 2104806 R 204722 CDS NP_699157.1 23503030 1167886 2105205..2106086 1 NC_004310.3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2106086 mutM 1167886 mutM Brucella suis 1330 formamidopyrimidine-DNA glycosylase NP_699157.1 2105205 D 204722 CDS NP_699158.1 23503031 1167887 2106213..2106986 1 NC_004310.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2106986 1167887 BR2184 Brucella suis 1330 enoyl-CoA hydratase NP_699158.1 2106213 D 204722 CDS NP_699159.1 23503032 1167888 2107322..2107588 1 NC_004310.3 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2107588 rpsT 1167888 rpsT Brucella suis 1330 30S ribosomal protein S20 NP_699159.1 2107322 D 204722 CDS NP_699208.1 23499768 1164437 155..1348 1 NC_004311.2 identified by match to PFAM protein family HMM PF03428; replication initiation protein RepC 1348 repC 1164437 repC Brucella suis 1330 replication initiation protein RepC NP_699208.1 155 D 204722 CDS NP_699209.1 23499769 1164438 complement(1413..1562) 1 NC_004311.2 hypothetical protein 1562 1164438 BRA0002 Brucella suis 1330 hypothetical protein NP_699209.1 1413 R 204722 CDS NP_699210.1 23499770 1164439 1551..1814 1 NC_004311.2 hypothetical protein 1814 1164439 BRA0003 Brucella suis 1330 hypothetical protein NP_699210.1 1551 D 204722 CDS NP_699211.1 23499771 1164440 1963..2076 1 NC_004311.2 hypothetical protein 2076 1164440 BRA0004 Brucella suis 1330 hypothetical protein NP_699211.1 1963 D 204722 CDS NP_699212.1 23499772 1164441 2092..3033 1 NC_004311.2 similar to GB:M77016, SP:P28289, PID:339948, GB:M77016, SP:P28289, and PID:339948; identified by sequence similarity; ribokinase 3033 1164441 BRA0005 Brucella suis 1330 ribokinase NP_699212.1 2092 D 204722 CDS NP_699213.1 23499773 1164442 complement(3110..4108) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase 4108 iunH 1164442 iunH Brucella suis 1330 inosine-uridine preferring nucleoside hydrolase NP_699213.1 3110 R 204722 CDS NP_699214.1 23499774 1164443 complement(4131..5042) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00023; ABC transporter permease 5042 1164443 BRA0007 Brucella suis 1330 ABC transporter permease NP_699214.1 4131 R 204722 CDS NP_699215.1 23499775 1164444 complement(5039..6118) 1 NC_004311.2 similar to GP:13022200, and GP:17134506; identified by sequence similarity; ABC transporter permease 6118 1164444 BRA0008 Brucella suis 1330 ABC transporter permease NP_699215.1 5039 R 204722 CDS NP_699216.1 23499776 1164445 complement(6180..7751) 1 NC_004311.2 similar to GP:13162075, GB:X52974, SP:P40598, and PID:48736; identified by sequence similarity; ABC transporter ATP-binding protein 7751 1164445 BRA0009 Brucella suis 1330 ABC transporter ATP-binding protein NP_699216.1 6180 R 204722 CDS NP_699217.1 23499777 1164446 complement(7754..8860) 1 NC_004311.2 similar to GP:11065692; identified by sequence similarity; Bmp family lipoprotein 8860 1164446 BRA0010 Brucella suis 1330 Bmp family lipoprotein NP_699217.1 7754 R 204722 CDS NP_699218.1 23499778 1164447 9104..9712 1 NC_004311.2 similar to GP:15141208, and GP:15141208; identified by sequence similarity; hypothetical protein 9712 1164447 BRA0011 Brucella suis 1330 hypothetical protein NP_699218.1 9104 D 204722 CDS NP_699219.1 23499779 1164448 complement(9684..10316) 1 NC_004311.2 similar to GP:15158815, and GP:6018425; identified by sequence similarity; enterobactin synthetase subunit D 10316 1164448 BRA0012 Brucella suis 1330 enterobactin synthetase subunit D NP_699219.1 9684 R 204722 CDS NP_699220.1 23499780 1164449 complement(10399..11175) 1 NC_004311.2 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase 11175 entA 1164449 entA Brucella suis 1330 2,3-dihydroxybenzoate-2,3-dehydrogenase NP_699220.1 10399 R 204722 CDS NP_699221.1 23499781 1164450 complement(11175..12047) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00550; isochorismatase 12047 entB 1164450 entB Brucella suis 1330 isochorismatase NP_699221.1 11175 R 204722 CDS NP_699222.1 23499782 1164451 complement(12099..13718) 1 NC_004311.2 bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E 13718 entE 1164451 entE Brucella suis 1330 enterobactin synthase subunit E NP_699222.1 12099 R 204722 CDS NP_699223.1 23499783 1164452 complement(13825..15000) 1 NC_004311.2 synthesizes isochorismate acid from chorismate; isochorismate synthase 15000 entC 1164452 entC Brucella suis 1330 isochorismate synthase NP_699223.1 13825 R 204722 CDS NP_699224.1 23499784 1164453 15072..16481 1 NC_004311.2 similar to GP:13959028, and GP:1778502; identified by sequence similarity; enterobactin synthetase subunit F 16481 1164453 BRA0017 Brucella suis 1330 enterobactin synthetase subunit F NP_699224.1 15072 D 204722 CDS NP_699225.1 23499785 1164454 complement(16529..17317) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00174; molybdopterin-binding oxidoreductase 17317 1164454 BRA0018 Brucella suis 1330 molybdopterin-binding oxidoreductase NP_699225.1 16529 R 204722 CDS NP_699226.1 23499786 1164455 complement(17314..18123) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01292; HupC/HyaC/HydC family protein 18123 1164455 BRA0019 Brucella suis 1330 HupC/HyaC/HydC family protein NP_699226.1 17314 R 204722 CDS NP_699227.1 23499787 1164456 complement(18184..18423) 1 NC_004311.2 similar to GP:15157425, and GP:15157425; identified by sequence similarity; hypothetical protein 18423 1164456 BRA0020 Brucella suis 1330 hypothetical protein NP_699227.1 18184 R 204722 CDS NP_699228.1 23499788 1164457 18608..19132 1 NC_004311.2 similar to GP:15157424; identified by sequence similarity; ECF subfamily RNA polymerase sigma factor 19132 1164457 BRA0021 Brucella suis 1330 ECF subfamily RNA polymerase sigma factor NP_699228.1 18608 D 204722 CDS NP_699229.1 23499789 1164458 19122..19757 1 NC_004311.2 similar to GP:15157423, and GP:15157423; identified by sequence similarity; hypothetical protein 19757 1164458 BRA0022 Brucella suis 1330 hypothetical protein NP_699229.1 19122 D 204722 CDS NP_699230.1 23499790 1164459 complement(19803..20543) 1 NC_004311.2 similar to GP:14523197; identified by sequence similarity; GntR family transcriptional regulator 20543 1164459 BRA0023 Brucella suis 1330 GntR family transcriptional regulator NP_699230.1 19803 R 204722 CDS NP_699231.1 23499791 1164460 20661..22076 1 NC_004311.2 similar to GB:Z11566, GB:J04991, GB:X53305, GB:M31303, GB:D28428, GB:X94912, SP:P16949, PID:1246757, PID:189388, PID:189426, PID:35595, and PID:57870; identified by sequence similarity; branched chain amino acid ABC transporter periplasmic amino acid-binding protein 22076 1164460 BRA0024 Brucella suis 1330 branched chain amino acid ABC transporter periplasmic amino acid-binding protein NP_699231.1 20661 D 204722 CDS NP_699232.1 23499792 1164461 22118..23107 1 NC_004311.2 similar to GP:15076000; identified by sequence similarity; branched-chain amino acid ABC transporter permease 23107 1164461 BRA0025 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699232.1 22118 D 204722 CDS NP_699233.1 23499793 1164462 23111..24331 1 NC_004311.2 similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; branched-chain amino acid ABC transporter permease 24331 1164462 BRA0026 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699233.1 23111 D 204722 CDS NP_699234.1 23499794 1164463 24331..25083 1 NC_004311.2 similar to GP:15159144; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 25083 1164463 BRA0027 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_699234.1 24331 D 204722 CDS NP_699235.1 23499795 1164464 25083..25799 1 NC_004311.2 similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 25799 1164464 BRA0028 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_699235.1 25083 D 204722 CDS NP_699236.1 23499796 1164465 25851..26333 1 NC_004311.2 identified by match to PFAM protein family HMM PF00903; glyoxalase 26333 1164465 BRA0029 Brucella suis 1330 glyoxalase NP_699236.1 25851 D 204722 CDS NP_699237.1 23499797 1164466 26337..27074 1 NC_004311.2 similar to GB:L13289, SP:P47721, PID:551904, GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; 3-oxoacyl-ACP reductase 27074 1164466 BRA0030 Brucella suis 1330 3-oxoacyl-ACP reductase NP_699237.1 26337 D 204722 CDS NP_699238.1 23499798 1164467 27092..27844 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01500; short chain dehydrogenase/reductase oxidoreductase 27844 1164467 BRA0031 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_699238.1 27092 D 204722 CDS NP_699239.1 23499799 1164468 27954..30143 1 NC_004311.2 similar to SP:P27746, GB:X52592, and PID:46994; identified by sequence similarity; acetoin dehydrogenase, alpha/subunit beta 30143 1164468 BRA0032 Brucella suis 1330 acetoin dehydrogenase, alpha/subunit beta NP_699239.1 27954 D 204722 CDS NP_699240.1 23499800 1164469 30162..31427 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01348; branched-chain alpha-keto acid dehydrogenase subunit E2 31427 1164469 BRA0033 Brucella suis 1330 branched-chain alpha-keto acid dehydrogenase subunit E2 NP_699240.1 30162 D 204722 CDS NP_699241.1 23499801 1164470 31528..32313 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00507; shikimate dehydrogenase 32313 1164470 BRA0034 Brucella suis 1330 shikimate dehydrogenase NP_699241.1 31528 D 204722 CDS NP_699242.1 23499802 1164471 32593..32886 1 NC_004311.2 hypothetical protein 32886 1164471 BRA0035 Brucella suis 1330 hypothetical protein NP_699242.1 32593 D 204722 CDS NP_699243.1 23499803 1164472 complement(32840..33121) 1 NC_004311.2 hypothetical protein 33121 1164472 BRA0036 Brucella suis 1330 hypothetical protein NP_699243.1 32840 R 204722 CDS NP_699244.1 23499804 1164473 33239..35956 1 NC_004311.2 similar to GP:397973; identified by sequence similarity; magnesium ion-transporting ATPase E1-E2 family protein 35956 1164473 BRA0037 Brucella suis 1330 magnesium ion-transporting ATPase E1-E2 family protein NP_699244.1 33239 D 204722 CDS NP_699245.1 23499805 1164474 36041..36391 1 NC_004311.2 hypothetical protein 36391 1164474 BRA0038 Brucella suis 1330 hypothetical protein NP_699245.1 36041 D 204722 CDS NP_699246.1 23499806 1164475 36522..36725 1 NC_004311.2 hypothetical protein 36725 1164475 BRA0039 Brucella suis 1330 hypothetical protein NP_699246.1 36522 D 204722 CDS NP_699247.1 23499807 1164476 36727..37443 1 NC_004311.2 similar to GB:L33799, and PID:642908; identified by sequence similarity; MgtC family protein 37443 1164476 BRA0040 Brucella suis 1330 MgtC family protein NP_699247.1 36727 D 204722 CDS NP_699248.1 23499808 1164477 37518..38588 1 NC_004311.2 similar to GB:M57423, SP:P09329, SP:P11908, SP:P21108, PID:190522, and PID:2160401; identified by sequence similarity; sensor histidine kinase 38588 1164477 BRA0041 Brucella suis 1330 sensor histidine kinase NP_699248.1 37518 D 204722 CDS NP_699249.1 23499809 1164478 38585..39223 1 NC_004311.2 similar to GB:L22075, SP:Q14344, and PID:404722; identified by sequence similarity; LuxR family transcriptional regulator 39223 1164478 BRA0042 Brucella suis 1330 LuxR family transcriptional regulator NP_699249.1 38585 D 204722 CDS NP_699250.1 23499810 1164480 complement(39609..39971) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00072; response regulator 39971 1164480 BRA0043 Brucella suis 1330 response regulator NP_699250.1 39609 R 204722 CDS NP_699251.1 23499811 1164481 40290..41180 1 NC_004311.2 formiminoglutamase 41180 1164481 BRA0044 Brucella suis 1330 formiminoglutamase NP_699251.1 40290 D 204722 CDS NP_699252.1 23499812 1164482 41342..42118 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase 42118 1164482 BRA0045 Brucella suis 1330 inositol monophosphatase NP_699252.1 41342 D 204722 CDS NP_699253.1 23499813 1164483 complement(42169..43164) 1 NC_004311.2 similar to GB:X15949, SP:P14316, and PID:33967; identified by sequence similarity; lysophospholipase L2 43164 1164483 BRA0046 Brucella suis 1330 lysophospholipase L2 NP_699253.1 42169 R 204722 CDS NP_699254.1 23499814 1164484 complement(43204..43419) 1 NC_004311.2 hypothetical protein 43419 1164484 BRA0047 Brucella suis 1330 hypothetical protein NP_699254.1 43204 R 204722 CDS NP_699255.1 23499815 1164485 complement(43514..43912) 1 NC_004311.2 hypothetical protein 43912 1164485 BRA0048 Brucella suis 1330 hypothetical protein NP_699255.1 43514 R 204722 CDS NP_699256.1 23499816 1164486 43964..44173 1 NC_004311.2 hypothetical protein 44173 1164486 BRA0049 Brucella suis 1330 hypothetical protein NP_699256.1 43964 D 204722 CDS NP_699257.1 23499817 1164487 44146..44397 1 NC_004311.2 hypothetical protein 44397 1164487 BRA0050 Brucella suis 1330 hypothetical protein NP_699257.1 44146 D 204722 CDS NP_699258.1 23499818 1164488 44476..44946 1 NC_004311.2 similar to GB:X01703, GB:K00557, SP:P04687, SP:P05215, PID:340019, PID:340021, and PID:37492; identified by sequence similarity; 16 kDa heat shock protein A 44946 ibpA 1164488 ibpA Brucella suis 1330 16 kDa heat shock protein A NP_699258.1 44476 D 204722 CDS NP_699259.1 23499819 1164489 complement(45084..46133) 1 NC_004311.2 threonine aldolase 46133 1164489 BRA0052 Brucella suis 1330 threonine aldolase NP_699259.1 45084 R 204722 CDS NP_699260.1 23499820 1164490 complement(46402..46686) 1 NC_004311.2 hypothetical protein 46686 1164490 BRA0053 Brucella suis 1330 hypothetical protein NP_699260.1 46402 R 204722 CDS NP_699261.1 23499821 1164491 46776..51527 1 NC_004311.2 similar to SP:P04993, GB:X04581, GB:X04582, PID:42683, PID:42691, PID:882711, GB:U00096, and PID:1789182; identified by sequence similarity; glutamate synthase, large subunit 51527 gltB 1164491 gltB Brucella suis 1330 glutamate synthase, large subunit NP_699261.1 46776 D 204722 CDS NP_699262.1 23499822 1164492 51609..53063 1 NC_004311.2 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 53063 gltD 1164492 gltD Brucella suis 1330 glutamate synthase subunit beta NP_699262.1 51609 D 204722 CDS NP_699263.1 23499823 1164493 complement(53108..54511) 1 NC_004311.2 similar to SP:O06005, GB:M86808, SP:P29803, and PID:190790; identified by sequence similarity; amino acid permease 54511 1164493 BRA0056 Brucella suis 1330 amino acid permease NP_699263.1 53108 R 204722 CDS NP_699264.1 23499824 1164494 complement(54733..55884) 1 NC_004311.2 similar to GP:15075833; identified by sequence similarity; hypothetical protein 55884 1164494 BRA0057 Brucella suis 1330 hypothetical protein NP_699264.1 54733 R 204722 CDS NP_699265.1 23499825 1164495 complement(56135..56653) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00691; lipoprotein 56653 1164495 BRA0058 Brucella suis 1330 lipoprotein NP_699265.1 56135 R 204722 CDS NP_699266.1 23499826 1164496 complement(56802..57887) 1 NC_004311.2 similar to GP:5929876, and GP:8163894; identified by sequence similarity; type IV secretion system protein VirB11 57887 1164496 BRA0059 Brucella suis 1330 type IV secretion system protein VirB11 NP_699266.1 56802 R 204722 CDS NP_699267.1 23499827 1164497 complement(57868..59043) 1 NC_004311.2 similar to GP:5929875, and GP:5929875; identified by sequence similarity; type IV secretion system protein VirB10 59043 1164497 BRA0060 Brucella suis 1330 type IV secretion system protein VirB10 NP_699267.1 57868 R 204722 CDS NP_699268.1 23499828 1164498 complement(59040..59909) 1 NC_004311.2 similar to GP:5929874, and GP:5929874; identified by sequence similarity; type IV secretion system protein VirB9 59909 1164498 BRA0061 Brucella suis 1330 type IV secretion system protein VirB9 NP_699268.1 59040 R 204722 CDS NP_699269.1 23499829 1164499 complement(59906..60625) 1 NC_004311.2 similar to GP:5929873, and GP:5929873; identified by sequence similarity; type IV secretion system protein VirB8 60625 1164499 BRA0062 Brucella suis 1330 type IV secretion system protein VirB8 NP_699269.1 59906 R 204722 CDS NP_699270.1 23499830 1164500 complement(60628..60801) 1 NC_004311.2 similar to GP:5929872; identified by sequence similarity; type IV secretion system protein VirB7 60801 1164500 BRA0063 Brucella suis 1330 type IV secretion system protein VirB7 NP_699270.1 60628 R 204722 CDS NP_699271.1 23499831 1164501 complement(60965..62008) 1 NC_004311.2 similar to GP:8163889, and GP:8163889; identified by sequence similarity; type IV secretion system protein VirB6 62008 1164501 BRA0064 Brucella suis 1330 type IV secretion system protein VirB6 NP_699271.1 60965 R 204722 CDS NP_699272.1 23499832 1164502 complement(62192..62908) 1 NC_004311.2 similar to GP:5929870, and GP:5929870; identified by sequence similarity; type IV secretion system protein VirB5 62908 1164502 BRA0065 Brucella suis 1330 type IV secretion system protein VirB5 NP_699272.1 62192 R 204722 CDS NP_699273.1 23499833 1164503 complement(62913..65408) 1 NC_004311.2 similar to GP:8163887, and GP:8163887; identified by sequence similarity; type IV secretion system protein VirB4 65408 1164503 BRA0066 Brucella suis 1330 type IV secretion system protein VirB4 NP_699273.1 62913 R 204722 CDS NP_699274.1 23499834 1164504 complement(65408..65758) 1 NC_004311.2 similar to GP:5929868, and GP:5929868; identified by sequence similarity; type IV secretion system protein VirB3 65758 1164504 BRA0067 Brucella suis 1330 type IV secretion system protein VirB3 NP_699274.1 65408 R 204722 CDS NP_699275.1 23499835 1164505 complement(65772..66089) 1 NC_004311.2 similar to GP:5929867, and GP:5929867; identified by sequence similarity; type IV secretion system protein VirB2 66089 1164505 BRA0068 Brucella suis 1330 type IV secretion system protein VirB2 NP_699275.1 65772 R 204722 CDS NP_699276.1 23499836 1164506 complement(66525..67241) 1 NC_004311.2 similar to GP:5929866, and GP:5929866; identified by sequence similarity; type IV secretion system protein VirB1 67241 1164506 BRA0069 Brucella suis 1330 type IV secretion system protein VirB1 NP_699276.1 66525 R 204722 CDS NP_699277.1 23499837 1164507 complement(67745..68971) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01471; transglycosylase 68971 1164507 BRA0070 Brucella suis 1330 transglycosylase NP_699277.1 67745 R 204722 CDS NP_699278.1 23499838 1164508 69383..70276 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01208; UTP-glucose-1-phosphate uridylyltransferase 70276 galU 1164508 galU Brucella suis 1330 UTP-glucose-1-phosphate uridylyltransferase NP_699278.1 69383 D 204722 CDS NP_699279.1 23499839 1164509 complement(70329..71867) 1 NC_004311.2 similar to GP:14023404; identified by sequence similarity; hypothetical protein 71867 1164509 BRA0072 Brucella suis 1330 hypothetical protein NP_699279.1 70329 R 204722 CDS NP_699280.1 23499840 1164510 72008..73009 1 NC_004311.2 similar to GP:15159530; identified by sequence similarity; sugar isomerase KpsF/GutQ 73009 1164510 BRA0073 Brucella suis 1330 sugar isomerase KpsF/GutQ NP_699280.1 72008 D 204722 CDS NP_699281.1 23499841 1164511 complement(73148..73615) 1 NC_004311.2 hypothetical protein 73615 1164511 BRA0074 Brucella suis 1330 hypothetical protein NP_699281.1 73148 R 204722 CDS NP_699282.1 23499842 1164512 complement(73636..74622) 1 NC_004311.2 similar to GP:15159532; identified by sequence similarity; SPFH domain-containing protein/band 7 family protein 74622 1164512 BRA0075 Brucella suis 1330 SPFH domain-containing protein/band 7 family protein NP_699282.1 73636 R 204722 CDS NP_699283.1 23499843 1164513 complement(74755..75813) 1 NC_004311.2 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 75813 hemH 1164513 hemH Brucella suis 1330 ferrochelatase NP_699283.1 74755 R 204722 CDS NP_699284.1 23499844 1164514 complement(75951..76331) 1 NC_004311.2 similar to GP:13877130, and GP:13877130; identified by sequence similarity; lipoprotein Omp10 76331 omp10 1164514 omp10 Brucella suis 1330 lipoprotein Omp10 NP_699284.1 75951 R 204722 CDS NP_699285.1 23499845 1164515 complement(76473..77918) 1 NC_004311.2 similar to GP:2276407; identified by sequence similarity; homospermidine synthase 77918 1164515 BRA0078 Brucella suis 1330 homospermidine synthase NP_699285.1 76473 R 204722 CDS NP_699286.1 23499846 1164516 complement(78030..78710) 1 NC_004311.2 similar to GP:14023390, and GP:14023390; identified by sequence similarity; hypothetical protein 78710 1164516 BRA0079 Brucella suis 1330 hypothetical protein NP_699286.1 78030 R 204722 CDS NP_699287.1 23499847 1164517 complement(78644..79813) 1 NC_004311.2 catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase 79813 1164517 BRA0080 Brucella suis 1330 aminodeoxychorismate synthase NP_699287.1 78644 R 204722 CDS NP_699288.1 23499848 1164518 complement(79823..81685) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01432; oligoendopeptidase F 81685 pepF 1164518 pepF Brucella suis 1330 oligoendopeptidase F NP_699288.1 79823 R 204722 CDS NP_699289.1 23499849 1164519 82033..83523 1 NC_004311.2 similar to GP:15159542; identified by sequence similarity; Fis family transcriptional regulator 83523 1164519 BRA0082 Brucella suis 1330 Fis family transcriptional regulator NP_699289.1 82033 D 204722 CDS NP_699290.1 23499850 1164520 83864..85777 1 NC_004311.2 similar to GP:14023385; identified by sequence similarity; hypothetical protein 85777 1164520 BRA0083 Brucella suis 1330 hypothetical protein NP_699290.1 83864 D 204722 CDS NP_699291.1 23499851 1164523 87371..88297 1 NC_004311.2 identified by match to PFAM protein family HMM PF00581; rhodanese family protein 88297 1164523 BRA0086 Brucella suis 1330 rhodanese family protein NP_699291.1 87371 D 204722 CDS NP_699292.1 23499852 1164524 88332..88538 1 NC_004311.2 hypothetical protein 88538 1164524 BRA0087 Brucella suis 1330 hypothetical protein NP_699292.1 88332 D 204722 CDS NP_699293.1 23499853 1164525 88578..89333 1 NC_004311.2 similar to GP:15157753; identified by sequence similarity; molybdenum ABC transporter periplasmic molybdenum-binding protein 89333 modA 1164525 modA Brucella suis 1330 molybdenum ABC transporter periplasmic molybdenum-binding protein NP_699293.1 88578 D 204722 CDS NP_699294.1 23499854 1164526 89344..90030 1 NC_004311.2 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 90030 modB 1164526 modB Brucella suis 1330 molybdate ABC transporter permease NP_699294.1 89344 D 204722 CDS NP_699295.1 23499855 1164527 90027..91106 1 NC_004311.2 similar to SP:P09833; identified by sequence similarity; molybdenum ABC transporter ATP-binding protein 91106 modC 1164527 modC Brucella suis 1330 molybdenum ABC transporter ATP-binding protein NP_699295.1 90027 D 204722 CDS NP_699296.1 23499856 1164528 91176..91853 1 NC_004311.2 identified by match to PFAM protein family HMM PF00583; acetyltransferase 91853 1164528 BRA0091 Brucella suis 1330 acetyltransferase NP_699296.1 91176 D 204722 CDS NP_699297.1 23499857 1164529 91840..92049 1 NC_004311.2 hypothetical protein 92049 1164529 BRA0092 Brucella suis 1330 hypothetical protein NP_699297.1 91840 D 204722 CDS NP_699298.1 23499858 1164530 complement(92101..92454) 1 NC_004311.2 hypothetical protein 92454 1164530 BRA0094 Brucella suis 1330 hypothetical protein NP_699298.1 92101 R 204722 CDS NP_699300.1 23499860 1164532 complement(92511..92852) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01598; hypothetical protein 92852 1164532 BRA0095 Brucella suis 1330 hypothetical protein NP_699300.1 92511 R 204722 CDS NP_699301.1 23499861 1164533 complement(92994..94097) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03741; hypothetical protein 94097 1164533 BRA0096 Brucella suis 1330 hypothetical protein NP_699301.1 92994 R 204722 CDS NP_699302.1 23499862 1164534 complement(94097..94801) 1 NC_004311.2 similar to GP:15158721; identified by sequence similarity; hypothetical protein 94801 1164534 BRA0097 Brucella suis 1330 hypothetical protein NP_699302.1 94097 R 204722 CDS NP_699303.1 23499863 1164535 complement(94841..95734) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02492; LysR family transcriptional regulator 95734 1164535 BRA0098 Brucella suis 1330 LysR family transcriptional regulator NP_699303.1 94841 R 204722 CDS NP_699304.1 23499864 1164536 complement(95738..96943) 1 NC_004311.2 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 96943 1164536 BRA0099 Brucella suis 1330 amidase NP_699304.1 95738 R 204722 CDS NP_699305.1 23499865 1164537 97528..98661 1 NC_004311.2 similar to SP:O50657; identified by sequence similarity; ornithine/DAP/arginine decarboxylase decarboxylase 2 98661 1164537 BRA0100 Brucella suis 1330 ornithine/DAP/arginine decarboxylase decarboxylase 2 NP_699305.1 97528 D 204722 CDS NP_699306.1 23499866 1164538 complement(98737..100455) 1 NC_004311.2 similar to GP:15141223; identified by sequence similarity; polysaccharide accessory transport protein 100455 1164538 BRA0101 Brucella suis 1330 polysaccharide accessory transport protein NP_699306.1 98737 R 204722 CDS NP_699307.1 23499867 1164539 complement(100472..100609) 1 NC_004311.2 hypothetical protein 100609 1164539 BRA0102 Brucella suis 1330 hypothetical protein NP_699307.1 100472 R 204722 CDS NP_699308.1 23499868 1164540 complement(100581..101483) 1 NC_004311.2 similar to GP:14026189; identified by sequence similarity; hypothetical protein 101483 1164540 BRA0103 Brucella suis 1330 hypothetical protein NP_699308.1 100581 R 204722 CDS NP_699309.1 23499869 1164541 complement(101441..102202) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03808; WecB/TagA/CpsF family glycosyl transferase 102202 1164541 BRA0104 Brucella suis 1330 WecB/TagA/CpsF family glycosyl transferase NP_699309.1 101441 R 204722 CDS NP_699310.1 23499870 1164542 complement(102203..103357) 1 NC_004311.2 hypothetical protein 103357 1164542 BRA0105 Brucella suis 1330 hypothetical protein NP_699310.1 102203 R 204722 CDS NP_699311.1 23499871 1164543 103351..103479 1 NC_004311.2 hypothetical protein 103479 1164543 BRA0106 Brucella suis 1330 hypothetical protein NP_699311.1 103351 D 204722 CDS NP_699312.1 23499872 1164544 103529..104521 1 NC_004311.2 identified by match to PFAM protein family HMM PF00535; glycosyl transferase group 2 family protein 104521 1164544 BRA0107 Brucella suis 1330 glycosyl transferase group 2 family protein NP_699312.1 103529 D 204722 CDS NP_699313.1 23499873 1164545 104490..105815 1 NC_004311.2 exopolysaccharide production protein 105815 1164545 BRA0108 Brucella suis 1330 exopolysaccharide production protein NP_699313.1 104490 D 204722 CDS NP_699314.1 23499874 1164546 105829..106965 1 NC_004311.2 similar to GP:15076091; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 106965 1164546 BRA0109 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699314.1 105829 D 204722 CDS NP_699315.1 23499875 1164547 complement(106962..108011) 1 NC_004311.2 similar to GP:6469270; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 108011 1164547 BRA0110 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699315.1 106962 R 204722 CDS NP_699316.1 23499876 1164548 108328..109737 1 NC_004311.2 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 109737 gnd 1164548 gnd Brucella suis 1330 6-phosphogluconate dehydrogenase NP_699316.1 108328 D 204722 CDS NP_699317.1 23499877 1164549 complement(109833..110894) 1 NC_004311.2 similar to GP:15157291; identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein 110894 1164549 BRA0112 Brucella suis 1330 spermidine/putrescine ABC transporter ATP-binding protein NP_699317.1 109833 R 204722 CDS NP_699318.1 23499878 1164550 complement(110900..111718) 1 NC_004311.2 similar to GP:15075242, and GP:17740614; identified by sequence similarity; spermidine/putrescine ABC transporter permease 111718 1164550 BRA0113 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_699318.1 110900 R 204722 CDS NP_699319.1 23499879 1164551 complement(111724..112608) 1 NC_004311.2 similar to GP:15075241, and GP:17740613; identified by sequence similarity; spermidine/putrescine ABC transporter permease 112608 1164551 BRA0114 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_699319.1 111724 R 204722 CDS NP_699320.1 23499880 1164552 complement(112817..113920) 1 NC_004311.2 similar to GP:15075240; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein 113920 1164552 BRA0115 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_699320.1 112817 R 204722 CDS NP_699321.1 23499881 1164553 complement(114329..115918) 1 NC_004311.2 identified by match to PFAM protein family HMM PF04039; Bcr/CflA subfamily drug resistance transporter 115918 1164553 BRA0116 Brucella suis 1330 Bcr/CflA subfamily drug resistance transporter NP_699321.1 114329 R 204722 CDS NP_699322.1 23499882 1164555 117353..118096 1 NC_004311.2 identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 118096 1164555 BRA0118 Brucella suis 1330 TetR family transcriptional regulator NP_699322.1 117353 D 204722 CDS NP_699323.1 23499883 1164556 118370..119149 1 NC_004311.2 similar to GP:9622950; identified by sequence similarity; LuxR family transcriptional regulator 119149 1164556 BRA0119 Brucella suis 1330 LuxR family transcriptional regulator NP_699323.1 118370 D 204722 CDS NP_699324.1 23499884 1164557 complement(119218..119637) 1 NC_004311.2 similar to GP:15073579, and GP:15073579; identified by sequence similarity; hypothetical protein 119637 1164557 BRA0120 Brucella suis 1330 hypothetical protein NP_699324.1 119218 R 204722 CDS NP_699325.1 23499885 1164558 complement(119757..120827) 1 NC_004311.2 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 120827 flhB 1164558 flhB Brucella suis 1330 flagellar biosynthesis protein FlhB NP_699325.1 119757 R 204722 CDS NP_699326.1 23499886 1164560 complement(121916..122236) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01052; flagellar motor switch protein FliN 122236 1164560 BRA0123 Brucella suis 1330 flagellar motor switch protein FliN NP_699326.1 121916 R 204722 CDS NP_699327.1 23499887 1164561 complement(122260..122721) 1 NC_004311.2 hypothetical protein 122721 1164561 BRA0124 Brucella suis 1330 hypothetical protein NP_699327.1 122260 R 204722 CDS NP_699328.1 23499888 1164562 complement(122702..123652) 1 NC_004311.2 similar to SP:O54246; identified by sequence similarity; flagellar motor switch protein FliM 123652 1164562 BRA0125 Brucella suis 1330 flagellar motor switch protein FliM NP_699328.1 122702 R 204722 CDS NP_699329.1 23499889 1164563 complement(123654..124526) 1 NC_004311.2 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA 124526 motA 1164563 motA Brucella suis 1330 flagellar motor protein MotA NP_699329.1 123654 R 204722 CDS NP_699330.1 23499890 1164564 124684..125460 1 NC_004311.2 similar to GP:15155497, and GP:15073585; identified by sequence similarity; hypothetical protein 125460 1164564 BRA0127 Brucella suis 1330 hypothetical protein NP_699330.1 124684 D 204722 CDS NP_699331.1 23499891 1164565 125460..126191 1 NC_004311.2 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgF 126191 flgF 1164565 flgF Brucella suis 1330 flagellar basal body rod protein FlgF NP_699331.1 125460 D 204722 CDS NP_699332.1 23499892 1164566 126188..127456 1 NC_004311.2 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 127456 fliI 1164566 fliI Brucella suis 1330 flagellum-specific ATP synthase NP_699332.1 126188 D 204722 CDS NP_699333.1 23499893 1164567 127540..128058 1 NC_004311.2 similar to GP:2916792, and GP:2459710; identified by sequence similarity; hypothetical protein 128058 1164567 BRA0130 Brucella suis 1330 hypothetical protein NP_699333.1 127540 D 204722 CDS NP_699334.1 23499894 1164568 complement(128083..129060) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01569; PAP2 family protein 129060 1164568 BRA0131 Brucella suis 1330 PAP2 family protein NP_699334.1 128083 R 204722 CDS NP_699335.1 23499895 1164569 129048..129203 1 NC_004311.2 hypothetical protein 129203 1164569 BRA0132 Brucella suis 1330 hypothetical protein NP_699335.1 129048 D 204722 CDS NP_699336.1 23499896 1164570 complement(129358..129576) 1 NC_004311.2 hypothetical protein 129576 1164570 BRA0133 Brucella suis 1330 hypothetical protein NP_699336.1 129358 R 204722 CDS NP_699337.1 23499897 1164571 129604..129999 1 NC_004311.2 identified by match to PFAM protein family HMM PF03751; hypothetical protein 129999 1164571 BRA0134 Brucella suis 1330 hypothetical protein NP_699337.1 129604 D 204722 CDS NP_699338.1 23499898 1164572 129996..130976 1 NC_004311.2 similar to GB:Z17227, SP:Q08334, PID:393379, and PID:571296; identified by sequence similarity; glycosyl transferase group 2 family protein 130976 1164572 BRA0135 Brucella suis 1330 glycosyl transferase group 2 family protein NP_699338.1 129996 D 204722 CDS NP_699339.1 23499899 1164573 130960..131709 1 NC_004311.2 identified by match to PFAM protein family HMM PF03633; hypothetical protein 131709 1164573 BRA0136 Brucella suis 1330 hypothetical protein NP_699339.1 130960 D 204722 CDS NP_699340.1 23499900 1164574 131706..133142 1 NC_004311.2 similar to GP:4433524; identified by sequence similarity; dolichyl-phosphate-mannose-protein mannosyltransferase 133142 1164574 BRA0137 Brucella suis 1330 dolichyl-phosphate-mannose-protein mannosyltransferase NP_699340.1 131706 D 204722 CDS NP_699341.1 23499901 1164575 complement(133264..133386) 1 NC_004311.2 hypothetical protein 133386 1164575 BRA0138 Brucella suis 1330 hypothetical protein NP_699341.1 133264 R 204722 CDS NP_699342.1 23499902 1164576 133385..134341 1 NC_004311.2 similar to GP:15159134; identified by sequence similarity; AraC family transcriptional regulator 134341 1164576 BRA0139 Brucella suis 1330 AraC family transcriptional regulator NP_699342.1 133385 D 204722 CDS NP_699343.1 23499903 1164577 134603..134707 1 NC_004311.2 hypothetical protein 134707 1164577 BRA0140 Brucella suis 1330 hypothetical protein NP_699343.1 134603 D 204722 CDS NP_699344.1 23499904 1164578 134697..135134 1 NC_004311.2 identified by match to PFAM protein family HMM PF01527; SyrB family protein 135134 1164578 BRA0141 Brucella suis 1330 SyrB family protein NP_699344.1 134697 D 204722 CDS NP_699345.1 23499905 1164579 135156..135266 1 NC_004311.2 hypothetical protein 135266 1164579 BRA0142 Brucella suis 1330 hypothetical protein NP_699345.1 135156 D 204722 CDS NP_699346.1 23499906 1164580 complement(135328..136629) 1 NC_004311.2 similar to GP:5281442, GB:U12431, SP:P26378, PID:521144, and PID:905387; identified by sequence similarity; phthalate transporter 136629 1164580 BRA0143 Brucella suis 1330 phthalate transporter NP_699346.1 135328 R 204722 CDS NP_699347.1 23499907 1164581 complement(136655..137287) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00760; aldolase 137287 1164581 BRA0144 Brucella suis 1330 aldolase NP_699347.1 136655 R 204722 CDS NP_699348.1 23499908 1164582 complement(137313..138278) 1 NC_004311.2 similar to GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, PID:825718, GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, and PID:825718; identified by sequence similarity; hypothetical protein 138278 1164582 BRA0145 Brucella suis 1330 hypothetical protein NP_699348.1 137313 R 204722 CDS NP_699349.1 23499909 1164583 complement(138278..139069) 1 NC_004311.2 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; DeoR family transcriptional regulator 139069 1164583 BRA0146 Brucella suis 1330 DeoR family transcriptional regulator NP_699349.1 138278 R 204722 CDS NP_699350.1 23499910 1164584 complement(139066..139851) 1 NC_004311.2 similar to GP:10197687, GB:J03799, GB:X15005, GB:S37431, GB:M14199, GB:X61156, GB:U36484, SP:P08865, PID:1125065, PID:34272, and PID:386857; identified by sequence similarity; hydroxypyruvate isomerase 139851 1164584 BRA0147 Brucella suis 1330 hydroxypyruvate isomerase NP_699350.1 139066 R 204722 CDS NP_699351.1 23499911 1164585 complement(139851..141125) 1 NC_004311.2 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; hypothetical protein 141125 1164585 BRA0148 Brucella suis 1330 hypothetical protein NP_699351.1 139851 R 204722 CDS NP_699352.1 23499912 1164587 142185..142322 1 NC_004311.2 hypothetical protein 142322 1164587 BRA0150 Brucella suis 1330 hypothetical protein NP_699352.1 142185 D 204722 CDS NP_699353.1 23499913 1164588 142399..142779 1 NC_004311.2 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal-body rod protein FlgB 142779 flgB 1164588 flgB Brucella suis 1330 flagellar basal-body rod protein FlgB NP_699353.1 142399 D 204722 CDS NP_699354.1 23499914 1164589 142782..143204 1 NC_004311.2 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 143204 flgC 1164589 flgC Brucella suis 1330 flagellar basal body rod protein FlgC NP_699354.1 142782 D 204722 CDS NP_699355.1 23499915 1164590 143204..143539 1 NC_004311.2 forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar hook-basal body protein FliE 143539 fliE 1164590 fliE Brucella suis 1330 flagellar hook-basal body protein FliE NP_699355.1 143204 D 204722 CDS NP_699356.1 23499916 1164591 143625..144413 1 NC_004311.2 makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; flagellar basal body rod protein FlgG 144413 flgG 1164591 flgG Brucella suis 1330 flagellar basal body rod protein FlgG NP_699356.1 143625 D 204722 CDS NP_699357.1 23499917 1164592 144425..144907 1 NC_004311.2 required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body P-ring biosynthesis protein FlgA 144907 flgA 1164592 flgA Brucella suis 1330 flagellar basal body P-ring biosynthesis protein FlgA NP_699357.1 144425 D 204722 CDS NP_699358.2 161486704 1164593 145204..146277 1 NC_004311.2 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 146277 flgI 1164593 flgI Brucella suis 1330 flagellar basal body P-ring biosynthesis protein FlgA NP_699358.2 145204 D 204722 CDS NP_699359.1 23499919 1164594 146274..146846 1 NC_004311.2 similar to GP:12057224; identified by sequence similarity; hypothetical protein 146846 1164594 BRA0157 Brucella suis 1330 hypothetical protein NP_699359.1 146274 D 204722 CDS NP_699360.1 23499920 1164595 146843..147559 1 NC_004311.2 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 147559 flgH 1164595 flgH Brucella suis 1330 flagellar basal body L-ring protein NP_699360.1 146843 D 204722 CDS NP_699361.1 23499921 1164596 147572..148063 1 NC_004311.2 similar to GP:15073597, GB:X56253, GB:X56254, GB:X56255, GB:X56256, GB:X56257, GB:M16985, SP:P20645, PID:307147, and PID:825692; identified by sequence similarity; flagellar protein FliL 148063 1164596 BRA0159 Brucella suis 1330 flagellar protein FliL NP_699361.1 147572 D 204722 CDS NP_699362.1 23499922 1164597 148060..148800 1 NC_004311.2 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 148800 fliP 1164597 fliP Brucella suis 1330 flagellar biosynthesis protein FliP NP_699362.1 148060 D 204722 CDS NP_699363.1 23499923 1164598 148895..149389 1 NC_004311.2 hypothetical protein 149389 1164598 BRA0161 Brucella suis 1330 hypothetical protein NP_699363.1 148895 D 204722 CDS NP_699364.1 23499924 1164599 149402..149818 1 NC_004311.2 similar to GP:15130936; identified by sequence similarity; hypothetical protein 149818 1164599 BRA0162 Brucella suis 1330 hypothetical protein NP_699364.1 149402 D 204722 CDS NP_699365.1 23499925 1164600 complement(150014..150898) 1 NC_004311.2 similar to GP:3419687; identified by sequence similarity; LysR family transcriptional regulator 150898 1164600 BRA0163 Brucella suis 1330 LysR family transcriptional regulator NP_699365.1 150014 R 204722 CDS NP_699366.1 23499926 1164601 150950..151081 1 NC_004311.2 hypothetical protein 151081 1164601 BRA0164 Brucella suis 1330 hypothetical protein NP_699366.1 150950 D 204722 CDS NP_699367.1 23499927 1164602 complement(150981..151079) 1 NC_004311.2 hypothetical protein 151079 1164602 BRA0165 Brucella suis 1330 hypothetical protein NP_699367.1 150981 R 204722 CDS NP_699368.1 23499928 1164603 151078..152295 1 NC_004311.2 identified by match to PFAM protein family HMM PF02515; CAIB/BAIF family protein 152295 1164603 BRA0166 Brucella suis 1330 CAIB/BAIF family protein NP_699368.1 151078 D 204722 CDS NP_699369.1 23499929 1164604 152363..153199 1 NC_004311.2 identified by match to PFAM protein family HMM PF01524; hypothetical protein 153199 1164604 BRA0167 Brucella suis 1330 hypothetical protein NP_699369.1 152363 D 204722 CDS NP_699370.1 23499930 1164605 153193..154017 1 NC_004311.2 identified by match to PFAM protein family HMM PF03328; citrate lyase subunit beta 154017 1164605 BRA0168 Brucella suis 1330 citrate lyase subunit beta NP_699370.1 153193 D 204722 CDS NP_699371.1 23499931 1164606 complement(154212..154397) 1 NC_004311.2 hypothetical protein 154397 1164606 BRA0169 Brucella suis 1330 hypothetical protein NP_699371.1 154212 R 204722 CDS NP_699372.1 23499932 1164607 154467..155045 1 NC_004311.2 similar to GB:L25675, PID:409767, and SP:P53641; identified by sequence similarity; cytochrome b561 155045 1164607 BRA0170 Brucella suis 1330 cytochrome b561 NP_699372.1 154467 D 204722 CDS NP_699373.1 23499933 1164608 155544..155888 1 NC_004311.2 hypothetical protein 155888 1164608 BRA0171 Brucella suis 1330 hypothetical protein NP_699373.1 155544 D 204722 CDS NP_699374.1 23499934 1164609 155836..156243 1 NC_004311.2 hypothetical protein 156243 1164609 BRA0172 Brucella suis 1330 hypothetical protein NP_699374.1 155836 D 204722 CDS NP_699375.1 23499935 1164610 156288..159629 1 NC_004311.2 similar to GP:15162141, and GP:15162141; identified by sequence similarity; outer membrane autotransporter 159629 1164610 BRA0173 Brucella suis 1330 outer membrane autotransporter NP_699375.1 156288 D 204722 CDS NP_699376.1 23499936 1164611 159865..160260 1 NC_004311.2 similar to GB:L11566, SP:Q07020, PID:337493, GB:L11566, SP:Q07020, and PID:337493; identified by sequence similarity; cytochrome c2 160260 cycA 1164611 cycA Brucella suis 1330 cytochrome c2 NP_699376.1 159865 D 204722 CDS NP_699377.1 23499937 1164612 complement(160484..160723) 1 NC_004311.2 hypothetical protein 160723 1164612 BRA0175 Brucella suis 1330 hypothetical protein NP_699377.1 160484 R 204722 CDS NP_699378.1 23499938 1164613 161154..161291 1 NC_004311.2 hypothetical protein 161291 1164613 BRA0176 Brucella suis 1330 hypothetical protein NP_699378.1 161154 D 204722 CDS NP_699379.1 23499939 1164614 complement(161369..162181) 1 NC_004311.2 similar to GP:15073704; identified by sequence similarity; GntR family transcriptional regulator 162181 1164614 BRA0177 Brucella suis 1330 GntR family transcriptional regulator NP_699379.1 161369 R 204722 CDS NP_699380.1 23499940 1164615 complement(162303..163223) 1 NC_004311.2 similar to GP:15073706; identified by sequence similarity; LysR family transcriptional regulator 163223 1164615 BRA0178 Brucella suis 1330 LysR family transcriptional regulator NP_699380.1 162303 R 204722 CDS NP_699381.1 23499941 1164616 complement(163383..163502) 1 NC_004311.2 hypothetical protein 163502 1164616 BRA0179 Brucella suis 1330 hypothetical protein NP_699381.1 163383 R 204722 CDS NP_699382.1 23499942 1164617 163574..165070 1 NC_004311.2 similar to SP:P32718, PID:396419, GB:U00096, and PID:1790522; identified by sequence similarity; glycolate oxidase subunit GlcD 165070 glcD 1164617 glcD Brucella suis 1330 glycolate oxidase subunit GlcD NP_699382.1 163574 D 204722 CDS NP_699383.1 23499943 1164618 165086..166318 1 NC_004311.2 similar to GP:14026515, and SP:P52073; identified by sequence similarity; glycolate oxidase subunit GlcE 166318 glcE 1164618 glcE Brucella suis 1330 glycolate oxidase subunit GlcE NP_699383.1 165086 D 204722 CDS NP_699384.1 23499944 1164619 166323..167624 1 NC_004311.2 similar to SP:P52074; identified by sequence similarity; glycolate oxidase, iron-sulfur subunit 167624 glcF 1164619 glcF Brucella suis 1330 glycolate oxidase, iron-sulfur subunit NP_699384.1 166323 D 204722 CDS NP_699385.1 23499945 1164620 complement(167848..168675) 1 NC_004311.2 similar to GP:4007669; identified by sequence similarity; aldo/keto reductase 168675 1164620 BRA0183 Brucella suis 1330 aldo/keto reductase NP_699385.1 167848 R 204722 CDS NP_699386.1 23499946 1164621 complement(168951..169685) 1 NC_004311.2 similar to GP:15155625, and GP:15073711; identified by sequence similarity; hypothetical protein 169685 1164621 BRA0184 Brucella suis 1330 hypothetical protein NP_699386.1 168951 R 204722 CDS NP_699387.1 23499947 1164622 169925..170581 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00624; DNA-3-methyladenine glycosidase I 170581 tag 1164622 tag Brucella suis 1330 DNA-3-methyladenine glycosidase I NP_699387.1 169925 D 204722 CDS NP_699388.1 23499948 1164623 170700..171317 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00948; amino acid transporter LysE 171317 1164623 BRA0186 Brucella suis 1330 amino acid transporter LysE NP_699388.1 170700 D 204722 CDS NP_699389.1 23499949 1164624 171428..172936 1 NC_004311.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 172936 hisS 1164624 hisS Brucella suis 1330 histidyl-tRNA synthetase NP_699389.1 171428 D 204722 CDS NP_699390.1 23499950 1164625 172945..174075 1 NC_004311.2 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 174075 hisZ 1164625 hisZ Brucella suis 1330 ATP phosphoribosyltransferase NP_699390.1 172945 D 204722 CDS NP_699391.1 23499951 1164626 174072..174767 1 NC_004311.2 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 174767 hisG 1164626 hisG Brucella suis 1330 ATP phosphoribosyltransferase NP_699391.1 174072 D 204722 CDS NP_699392.1 23499952 1164628 complement(176364..176765) 1 NC_004311.2 hypothetical protein 176765 1164628 BRA0191 Brucella suis 1330 hypothetical protein NP_699392.1 176364 R 204722 CDS NP_699393.1 23499953 1164629 complement(176868..178259) 1 NC_004311.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 178259 fumC 1164629 fumC Brucella suis 1330 fumarate hydratase NP_699393.1 176868 R 204722 CDS NP_699394.1 23499954 1164630 complement(178409..178696) 1 NC_004311.2 hypothetical protein 178696 1164630 BRA0193 Brucella suis 1330 hypothetical protein NP_699394.1 178409 R 204722 CDS NP_699395.1 23499955 1164631 complement(178993..179214) 1 NC_004311.2 hypothetical protein 179214 1164631 BRA0194 Brucella suis 1330 hypothetical protein NP_699395.1 178993 R 204722 CDS NP_699396.1 23499956 1164632 complement(179416..181056) 1 NC_004311.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 181056 groEL 1164632 groEL Brucella suis 1330 molecular chaperone GroEL NP_699396.1 179416 R 204722 CDS NP_699397.1 23499957 1164633 complement(181147..181443) 1 NC_004311.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 181443 groES 1164633 groES Brucella suis 1330 co-chaperonin GroES NP_699397.1 181147 R 204722 CDS NP_699398.1 23499958 1164634 181563..181703 1 NC_004311.2 hypothetical protein 181703 1164634 BRA0197 Brucella suis 1330 hypothetical protein NP_699398.1 181563 D 204722 CDS NP_699399.1 23499959 1164635 complement(181756..181860) 1 NC_004311.2 hypothetical protein 181860 1164635 BRA0198 Brucella suis 1330 hypothetical protein NP_699399.1 181756 R 204722 CDS NP_699400.1 23499960 1164636 181921..182772 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 182772 1164636 BRA0199 Brucella suis 1330 HAD superfamily hydrolase NP_699400.1 181921 D 204722 CDS NP_699401.1 23499961 1164637 182808..182921 1 NC_004311.2 hypothetical protein 182921 1164637 BRA0200 Brucella suis 1330 hypothetical protein NP_699401.1 182808 D 204722 CDS NP_699402.1 23499962 1164638 182902..183849 1 NC_004311.2 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 183849 ribF 1164638 ribF Brucella suis 1330 bifunctional riboflavin kinase/FMN adenylyltransferase NP_699402.1 182902 D 204722 CDS NP_699403.1 23499963 1164639 184193..187111 1 NC_004311.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 187111 ileS 1164639 ileS Brucella suis 1330 isoleucyl-tRNA synthetase NP_699403.1 184193 D 204722 CDS NP_699404.1 23499964 1164640 187303..187974 1 NC_004311.2 similar to GP:15073729; identified by sequence similarity; hypothetical protein 187974 1164640 BRA0203 Brucella suis 1330 hypothetical protein NP_699404.1 187303 D 204722 CDS NP_699405.1 23499965 1164641 188319..188879 1 NC_004311.2 similar to SP:P08732; identified by sequence similarity; cytochrome b561 188879 1164641 BRA0204 Brucella suis 1330 cytochrome b561 NP_699405.1 188319 D 204722 CDS NP_699406.1 23499966 1164642 complement(188933..189406) 1 NC_004311.2 similar to GP:15155649; identified by sequence similarity; cytidine and deoxycytidylate deaminase 189406 1164642 BRA0205 Brucella suis 1330 cytidine and deoxycytidylate deaminase NP_699406.1 188933 R 204722 CDS YP_002519390.1 221090247 1164643 189496..191292 1 NC_004311.2 RNA pseudouridylate synthase 191292 1164643 BRA0206 Brucella suis 1330 RNA pseudouridylate synthase YP_002519390.1 189496 D 204722 CDS NP_699407.1 23499967 1164644 191273..191836 1 NC_004311.2 identified by match to PFAM protein family HMM PF03602; hypothetical protein 191836 1164644 BRA0207 Brucella suis 1330 hypothetical protein NP_699407.1 191273 D 204722 CDS NP_699408.1 23499968 1164646 194810..195691 1 NC_004311.2 identified by match to PFAM protein family HMM PF01734; hypothetical protein 195691 1164646 BRA0209 Brucella suis 1330 hypothetical protein NP_699408.1 194810 D 204722 CDS NP_699409.1 23499969 1164647 complement(195704..197611) 1 NC_004311.2 similar to GP:15073737; identified by sequence similarity; glutathione-regulated potassium-efflux system protein 197611 1164647 BRA0210 Brucella suis 1330 glutathione-regulated potassium-efflux system protein NP_699409.1 195704 R 204722 CDS NP_699410.1 23499970 1164648 197750..199093 1 NC_004311.2 similar to GB:V00566, GB:J00299, GB:M29386, GB:D00411, SP:P01236, GB:U75583, PID:1620399, PID:1658518, PID:190354, PID:190356, PID:220018, PID:34211, PID:531101, and PID:531103; identified by sequence similarity; pmbA protein 199093 pmbA 1164648 pmbA Brucella suis 1330 pmbA protein NP_699410.1 197750 D 204722 CDS NP_699411.1 23499971 1164649 199125..199889 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase 199889 1164649 BRA0212 Brucella suis 1330 inositol monophosphatase NP_699411.1 199125 D 204722 CDS NP_699412.1 23499972 1164650 199928..200179 1 NC_004311.2 similar to GP:15155658, and GP:15073740; identified by sequence similarity; hypothetical protein 200179 1164650 BRA0213 Brucella suis 1330 hypothetical protein NP_699412.1 199928 D 204722 CDS NP_699413.1 23499973 1164651 200243..200986 1 NC_004311.2 similar to GP:14027592; identified by sequence similarity; hypothetical protein 200986 1164651 BRA0214 Brucella suis 1330 hypothetical protein NP_699413.1 200243 D 204722 CDS NP_699414.1 23499974 1164652 200983..202323 1 NC_004311.2 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 202323 kdtA 1164652 kdtA Brucella suis 1330 3-deoxy-D-manno-octulosonic-acid transferase NP_699414.1 200983 D 204722 CDS NP_699415.1 23499975 1164653 202326..203351 1 NC_004311.2 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 203351 lpxK 1164653 lpxK Brucella suis 1330 tetraacyldisaccharide 4'-kinase NP_699415.1 202326 D 204722 CDS NP_699416.1 23499976 1164654 complement(203365..203601) 1 NC_004311.2 similar to GP:15073746; identified by sequence similarity; hypothetical protein 203601 1164654 BRA0217 Brucella suis 1330 hypothetical protein NP_699416.1 203365 R 204722 CDS NP_699417.1 23499977 1164655 complement(203699..205570) 1 NC_004311.2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 205570 mutL 1164655 mutL Brucella suis 1330 DNA mismatch repair protein NP_699417.1 203699 R 204722 CDS NP_699418.1 23499978 1164656 complement(205754..207037) 1 NC_004311.2 similar to GB:Z25795, SP:P39118, PID:397488, PID:2293136, GB:AL009126, GB:Z25795, SP:P39118, PID:397488, PID:2293136, and GB:AL009126; identified by sequence similarity; cis,cis-muconate transport protein MucK 207037 mucK 1164656 mucK Brucella suis 1330 cis,cis-muconate transport protein MucK NP_699418.1 205754 R 204722 CDS NP_699419.1 23499979 1164657 complement(207135..208289) 1 NC_004311.2 similar to SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase 208289 1164657 BRA0220 Brucella suis 1330 acyl-CoA dehydrogenase NP_699419.1 207135 R 204722 CDS NP_699420.1 23499980 1164658 complement(208346..209200) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator 209200 1164658 BRA0221 Brucella suis 1330 IclR family transcriptional regulator NP_699420.1 208346 R 204722 CDS NP_699421.1 23499981 1164659 209460..210221 1 NC_004311.2 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 210221 1164659 BRA0222 Brucella suis 1330 enoyl-CoA hydratase NP_699421.1 209460 D 204722 CDS NP_699422.1 23499982 1164660 210226..211755 1 NC_004311.2 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 211755 1164660 BRA0223 Brucella suis 1330 3-hydroxyacyl-CoA dehydrogenase NP_699422.1 210226 D 204722 CDS NP_699423.1 23499983 1164661 211978..213219 1 NC_004311.2 similar to GP:14587414; identified by sequence similarity; CAIB/BAIF family protein 213219 1164661 BRA0224 Brucella suis 1330 CAIB/BAIF family protein NP_699423.1 211978 D 204722 CDS NP_699424.1 23499984 1164663 214457..214921 1 NC_004311.2 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 214921 1164663 BRA0226 Brucella suis 1330 MerR family transcriptional regulator NP_699424.1 214457 D 204722 CDS NP_699425.1 23499985 1164664 complement(214967..215674) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01382; ThiJ/PfpI family protein 215674 1164664 BRA0227 Brucella suis 1330 ThiJ/PfpI family protein NP_699425.1 214967 R 204722 CDS NP_699426.1 23499986 1164665 complement(215905..217245) 1 NC_004311.2 similar to GP:15159266; identified by sequence similarity; sensor histidine kinase 217245 1164665 BRA0228 Brucella suis 1330 sensor histidine kinase NP_699426.1 215905 R 204722 CDS NP_699427.1 23499987 1164667 complement(218041..218205) 1 NC_004311.2 hypothetical protein 218205 1164667 BRA0230 Brucella suis 1330 hypothetical protein NP_699427.1 218041 R 204722 CDS NP_699428.1 23499988 1164668 218177..218449 1 NC_004311.2 hypothetical protein 218449 1164668 BRA0231 Brucella suis 1330 hypothetical protein NP_699428.1 218177 D 204722 CDS NP_699429.1 23499989 1164669 218617..219087 1 NC_004311.2 hypothetical protein 219087 1164669 BRA0232 Brucella suis 1330 hypothetical protein NP_699429.1 218617 D 204722 CDS NP_699430.1 23499990 1164670 219098..221302 1 NC_004311.2 identified by match to PFAM protein family HMM PF03929; FAD-binding oxidoreductase 221302 1164670 BRA0233 Brucella suis 1330 FAD-binding oxidoreductase NP_699430.1 219098 D 204722 CDS NP_699431.1 23499991 1164671 221283..222260 1 NC_004311.2 similar to SP:P41780; identified by sequence similarity; ApbE family protein 222260 1164671 BRA0234 Brucella suis 1330 ApbE family protein NP_699431.1 221283 D 204722 CDS NP_699432.1 23499992 1164672 complement(222303..223478) 1 NC_004311.2 similar to GP:15073890; identified by sequence similarity; GAF/GGDEF domain-containing protein 223478 1164672 BRA0235 Brucella suis 1330 GAF/GGDEF domain-containing protein NP_699432.1 222303 R 204722 CDS NP_699433.1 23499993 1164673 complement(223761..224654) 1 NC_004311.2 similar to GP:15159282; identified by sequence similarity; hypothetical protein 224654 1164673 BRA0236 Brucella suis 1330 hypothetical protein NP_699433.1 223761 R 204722 CDS NP_699434.1 23499994 1164674 224630..224770 1 NC_004311.2 hypothetical protein 224770 1164674 BRA0237 Brucella suis 1330 hypothetical protein NP_699434.1 224630 D 204722 CDS NP_699435.1 23499995 1164675 224894..225571 1 NC_004311.2 similar to GP:15140120; identified by sequence similarity; GntR family transcriptional regulator 225571 1164675 BRA0238 Brucella suis 1330 GntR family transcriptional regulator NP_699435.1 224894 D 204722 CDS NP_699436.1 23499996 1164676 225672..226634 1 NC_004311.2 similar to GP:15140121; identified by sequence similarity; dihydrodipicolinate synthase 226634 1164676 BRA0239 Brucella suis 1330 dihydrodipicolinate synthase NP_699436.1 225672 D 204722 CDS NP_699437.1 23499997 1164677 complement(226697..227734) 1 NC_004311.2 similar to GP:15140123; identified by sequence similarity; malate/L-lactate dehydrogenase 227734 1164677 BRA0240 Brucella suis 1330 malate/L-lactate dehydrogenase NP_699437.1 226697 R 204722 CDS NP_699438.1 23499998 1164678 complement(227748..227849) 1 NC_004311.2 hypothetical protein 227849 1164678 BRA0241 Brucella suis 1330 hypothetical protein NP_699438.1 227748 R 204722 CDS NP_699439.1 23499999 1164679 complement(227853..227951) 1 NC_004311.2 hypothetical protein 227951 1164679 BRA0242 Brucella suis 1330 hypothetical protein NP_699439.1 227853 R 204722 CDS NP_699440.1 23500000 1164680 227971..229239 1 NC_004311.2 identified by match to PFAM protein family HMM PF03772; hypothetical protein 229239 1164680 BRA0243 Brucella suis 1330 hypothetical protein NP_699440.1 227971 D 204722 CDS NP_699441.1 23500001 1164681 complement(229247..229720) 1 NC_004311.2 similar to GP:6978955; identified by sequence similarity; hypothetical protein 229720 1164681 BRA0244 Brucella suis 1330 hypothetical protein NP_699441.1 229247 R 204722 CDS NP_699442.1 23500002 1164682 complement(229777..229932) 1 NC_004311.2 similar to GP:6978956, and GP:6978956; identified by sequence similarity; hypothetical protein 229932 1164682 BRA0245 Brucella suis 1330 hypothetical protein NP_699442.1 229777 R 204722 CDS NP_699443.1 23500003 1164683 230036..230605 1 NC_004311.2 similar to GP:6978957; identified by sequence similarity; cytochrome c oxidase subunit III 230605 1164683 BRA0246 Brucella suis 1330 cytochrome c oxidase subunit III NP_699443.1 230036 D 204722 CDS NP_699444.1 23500004 1164684 230613..230891 1 NC_004311.2 similar to GP:6978958, and GP:6978958; identified by sequence similarity; norF protein 230891 norF 1164684 norF Brucella suis 1330 norF protein NP_699444.1 230613 D 204722 CDS NP_699445.1 23500005 1164685 231051..231503 1 NC_004311.2 similar to GP:6978959, and SP:Q51662; identified by sequence similarity; nitric-oxide reductase, small subunit 231503 norC 1164685 norC Brucella suis 1330 nitric-oxide reductase, small subunit NP_699445.1 231051 D 204722 CDS NP_699446.1 23500006 1164686 231529..232878 1 NC_004311.2 similar to GP:6978960, and SP:P98008; identified by sequence similarity; nitric-oxide reductase, large subunit 232878 norB 1164686 norB Brucella suis 1330 nitric-oxide reductase, large subunit NP_699446.1 231529 D 204722 CDS NP_699447.1 23500007 1164687 232969..233781 1 NC_004311.2 similar to GP:6978961, GB:U10072, SP:P98177, and PID:501087; identified by sequence similarity; CbbQ/NirQ/NorQ/GpvN family protein 233781 1164687 BRA0250 Brucella suis 1330 CbbQ/NirQ/NorQ/GpvN family protein NP_699447.1 232969 D 204722 CDS NP_699448.1 23500008 1164688 233793..235694 1 NC_004311.2 similar to GP:6978962, GB:K00396, GB:M10065, GB:M12529, GB:X00199, GB:Z70760, GB:X92000, SP:P02649, PID:1263123, PID:178849, PID:178851, PID:178853, PID:579590, and PID:929610; identified by sequence similarity; norD protein 235694 norD 1164688 norD Brucella suis 1330 norD protein NP_699448.1 233793 D 204722 CDS NP_699449.1 23500009 1164689 235874..236158 1 NC_004311.2 similar to GP:14523804; identified by sequence similarity; hypothetical protein 236158 1164689 BRA0252 Brucella suis 1330 hypothetical protein NP_699449.1 235874 D 204722 CDS NP_699450.1 23500010 1164690 236194..237561 1 NC_004311.2 similar to GP:14523803, and GP:14523803; identified by sequence similarity; hypothetical protein 237561 1164690 BRA0253 Brucella suis 1330 hypothetical protein NP_699450.1 236194 D 204722 CDS NP_699451.1 23500011 1164691 237558..238085 1 NC_004311.2 similar to GP:14523802, and GP:14523802; identified by sequence similarity; hypothetical protein 238085 1164691 BRA0254 Brucella suis 1330 hypothetical protein NP_699451.1 237558 D 204722 CDS NP_699452.1 23500012 1164692 238092..238418 1 NC_004311.2 similar to GP:14523801, and GP:14523801; identified by sequence similarity; hypothetical protein 238418 1164692 BRA0255 Brucella suis 1330 hypothetical protein NP_699452.1 238092 D 204722 CDS NP_699453.1 23500013 1164693 238542..239717 1 NC_004311.2 similar to GP:15156967, and GP:15156967; identified by sequence similarity; hypothetical protein 239717 1164693 BRA0256 Brucella suis 1330 hypothetical protein NP_699453.1 238542 D 204722 CDS NP_699454.1 23500014 1164694 239714..240298 1 NC_004311.2 similar to GP:15074522, and GP:15074522; identified by sequence similarity; hypothetical protein 240298 1164694 BRA0257 Brucella suis 1330 hypothetical protein NP_699454.1 239714 D 204722 CDS NP_699455.1 23500015 1164695 240249..240947 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01409; hypothetical protein 240947 1164695 BRA0258 Brucella suis 1330 hypothetical protein NP_699455.1 240249 D 204722 CDS NP_699456.1 23500016 1164696 241023..241172 1 NC_004311.2 hypothetical protein 241172 1164696 BRA0259 Brucella suis 1330 hypothetical protein NP_699456.1 241023 D 204722 CDS NP_699457.1 23500017 1164697 241303..242433 1 NC_004311.2 similar to GB:J05016, SP:P13667, PID:181508, GB:J05016, SP:P13667, and PID:181508; identified by sequence similarity; copper-containing nitrite reductase 242433 1164697 BRA0260 Brucella suis 1330 copper-containing nitrite reductase NP_699457.1 241303 D 204722 CDS NP_699458.1 23500018 1164698 242566..243486 1 NC_004311.2 similar to GP:14523796, and GP:2773329; identified by sequence similarity; NirV protein 243486 1164698 BRA0261 Brucella suis 1330 NirV protein NP_699458.1 242566 D 204722 CDS NP_699459.1 23500019 1164699 243587..244282 1 NC_004311.2 similar to GP:6978954; identified by sequence similarity; Crp/Fnr family transcriptional regulator 244282 1164699 BRA0262 Brucella suis 1330 Crp/Fnr family transcriptional regulator NP_699459.1 243587 D 204722 CDS NP_699460.1 23500020 1164700 244365..245420 1 NC_004311.2 similar to GP:15140338; identified by sequence similarity; LacI family sugar-binding transcriptional regulator 245420 1164700 BRA0263 Brucella suis 1330 LacI family sugar-binding transcriptional regulator NP_699460.1 244365 D 204722 CDS NP_699461.1 23500021 1164701 complement(245601..245822) 1 NC_004311.2 hypothetical protein 245822 1164701 BRA0264 Brucella suis 1330 hypothetical protein NP_699461.1 245601 R 204722 CDS NP_699462.1 23500022 1164702 245821..246873 1 NC_004311.2 similar to GP:2661681; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 246873 1164702 BRA0265 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_699462.1 245821 D 204722 CDS NP_699463.1 23500023 1164703 247178..248038 1 NC_004311.2 similar to GP:2661682, and GP:12659326; identified by sequence similarity; sugar ABC transporter ATP-binding protein 248038 1164703 BRA0266 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_699463.1 247178 D 204722 CDS NP_699464.1 23500024 1164704 248035..249273 1 NC_004311.2 similar to GP:2661683, and GP:2661683; identified by sequence similarity; sugar ABC transporter permease 249273 1164704 BRA0267 Brucella suis 1330 sugar ABC transporter permease NP_699464.1 248035 D 204722 CDS NP_699465.1 23500025 1164705 249560..250288 1 NC_004311.2 similar to GP:11036625, GB:M57506, GB:M57502, SP:P22362, PID:184506, and PID:339729; identified by sequence similarity; ribitol dehydrogenase 250288 1164705 BRA0268 Brucella suis 1330 ribitol dehydrogenase NP_699465.1 249560 D 204722 CDS NP_699466.1 23500026 1164706 250301..251905 1 NC_004311.2 similar to GP:15158921; identified by sequence similarity; ribitol kinase 251905 1164706 BRA0269 Brucella suis 1330 ribitol kinase NP_699466.1 250301 D 204722 CDS NP_699467.1 23500027 1164707 complement(252037..252702) 1 NC_004311.2 similar to GP:15158337, and GP:15158337; identified by sequence similarity; hypothetical protein 252702 1164707 BRA0270 Brucella suis 1330 hypothetical protein NP_699467.1 252037 R 204722 CDS NP_699468.1 23500028 1164708 complement(252699..253175) 1 NC_004311.2 similar to SP:P08500, GB:M18576, PID:551957, PID:581499, SP:P08500, GB:M18576, PID:551957, and PID:581499; identified by sequence similarity; hypothetical protein 253175 1164708 BRA0271 Brucella suis 1330 hypothetical protein NP_699468.1 252699 R 204722 CDS NP_699469.1 23500029 1164710 255470..255709 1 NC_004311.2 hypothetical protein 255709 1164710 BRA0273 Brucella suis 1330 hypothetical protein NP_699469.1 255470 D 204722 CDS NP_699470.1 23500030 1164711 255722..258085 1 NC_004311.2 similar to GP:14523755; identified by sequence similarity; transcriptional regulator NosR 258085 1164711 BRA0274 Brucella suis 1330 transcriptional regulator NosR NP_699470.1 255722 D 204722 CDS NP_699471.1 23500031 1164712 258106..260025 1 NC_004311.2 reduces nitrous oxide to nitrogen; nitrous-oxide reductase 260025 nosZ 1164712 nosZ Brucella suis 1330 nitrous-oxide reductase NP_699471.1 258106 D 204722 CDS NP_699472.1 23500032 1164713 260031..261425 1 NC_004311.2 similar to SP:P19843, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; copper ABC transporter periplasmic copper-binding protein 261425 nosD 1164713 nosD Brucella suis 1330 copper ABC transporter periplasmic copper-binding protein NP_699472.1 260031 D 204722 CDS NP_699473.1 23500033 1164714 261463..262413 1 NC_004311.2 similar to SP:P19844, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; copper ABC transporter ATP-binding protein 262413 nosF 1164714 nosF Brucella suis 1330 copper ABC transporter ATP-binding protein NP_699473.1 261463 D 204722 CDS NP_699474.1 23500034 1164715 262410..263240 1 NC_004311.2 similar to GP:2177176, GB:L06175, and PID:189449; identified by sequence similarity; nitrous-oxide reductase subunit NosY 263240 nosY 1164715 nosY Brucella suis 1330 nitrous-oxide reductase subunit NosY NP_699474.1 262410 D 204722 CDS NP_699475.1 23500035 1164716 263237..263776 1 NC_004311.2 similar to GP:2177177; identified by sequence similarity; protein disulfide isomerase 263776 1164716 BRA0279 Brucella suis 1330 protein disulfide isomerase NP_699475.1 263237 D 204722 CDS NP_699476.1 23500036 1164717 263788..264780 1 NC_004311.2 similar to GP:14523761, and GP:2177178; identified by sequence similarity; nosX protein 264780 1164717 BRA0280 Brucella suis 1330 nosX protein NP_699476.1 263788 D 204722 CDS NP_699477.1 23500037 1164718 264895..265593 1 NC_004311.2 similar to GP:15158856, GB:L06214, PID:153222, and PID:886941; identified by sequence similarity; transcriptional regulator NnrR 265593 nnrR 1164718 nnrR Brucella suis 1330 transcriptional regulator NnrR NP_699477.1 264895 D 204722 CDS YP_002519391.1 221090246 1164719 265731..266171 1 NC_004311.2 pseudoazurin 266171 1164719 BRA0282 Brucella suis 1330 pseudoazurin YP_002519391.1 265731 D 204722 CDS NP_699478.1 23500038 1164720 266222..267463 1 NC_004311.2 similar to GP:15158853, and GP:14523798; identified by sequence similarity; hypothetical protein 267463 1164720 BRA0283 Brucella suis 1330 hypothetical protein NP_699478.1 266222 D 204722 CDS NP_699479.1 23500039 1164721 complement(267537..268577) 1 NC_004311.2 ABC transporter periplasmic binding protein 268577 1164721 BRA0284 Brucella suis 1330 ABC transporter periplasmic binding protein NP_699479.1 267537 R 204722 CDS NP_699480.1 23500040 1164722 complement(268603..269394) 1 NC_004311.2 similar to GP:15158995; identified by sequence similarity; ABC transporter permease 269394 1164722 BRA0285 Brucella suis 1330 ABC transporter permease NP_699480.1 268603 R 204722 CDS NP_699481.1 23500041 1164723 complement(269391..270236) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00972; ABC transporter ATP binding protein 270236 1164723 BRA0286 Brucella suis 1330 ABC transporter ATP binding protein NP_699481.1 269391 R 204722 CDS NP_699482.1 23500042 1164724 270263..270565 1 NC_004311.2 hypothetical protein 270565 1164724 BRA0287 Brucella suis 1330 hypothetical protein NP_699482.1 270263 D 204722 CDS NP_699483.1 23500043 1164725 complement(270471..270614) 1 NC_004311.2 hypothetical protein 270614 1164725 BRA0288 Brucella suis 1330 hypothetical protein NP_699483.1 270471 R 204722 CDS NP_699484.1 23500044 1164726 complement(270663..271595) 1 NC_004311.2 similar to GP:15158836; identified by sequence similarity; protease 271595 1164726 BRA0289 Brucella suis 1330 protease NP_699484.1 270663 R 204722 CDS NP_699485.1 23500045 1164727 complement(271598..272575) 1 NC_004311.2 similar to GP:15158837; identified by sequence similarity; U32 family peptidase 272575 1164727 BRA0290 Brucella suis 1330 U32 family peptidase NP_699485.1 271598 R 204722 CDS NP_699486.1 23500046 1164728 complement(272566..273090) 1 NC_004311.2 similar to GP:15158838, and GP:15158838; identified by sequence similarity; hypothetical protein 273090 1164728 BRA0291 Brucella suis 1330 hypothetical protein NP_699486.1 272566 R 204722 CDS NP_699487.1 23500047 1164729 273204..274718 1 NC_004311.2 similar to GP:14523816; identified by sequence similarity; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 274718 ubiD 1164729 ubiD Brucella suis 1330 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_699487.1 273204 D 204722 CDS NP_699488.1 23500048 1164730 274715..275305 1 NC_004311.2 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 275305 1164730 BRA0293 Brucella suis 1330 3-octaprenyl-4-hydroxybenzoate carboxy-lyase NP_699488.1 274715 D 204722 CDS NP_699489.1 23500049 1164731 complement(275315..275851) 1 NC_004311.2 hypothetical protein 275851 1164731 BRA0294 Brucella suis 1330 hypothetical protein NP_699489.1 275315 R 204722 CDS NP_699490.1 23500050 1164732 complement(275848..276783) 1 NC_004311.2 peptidyl-prolyl cis-trans isomerase 276783 1164732 BRA0295 Brucella suis 1330 peptidyl-prolyl cis-trans isomerase NP_699490.1 275848 R 204722 CDS NP_699491.1 23500051 1164733 complement(276789..277514) 1 NC_004311.2 similar to GB:M64929, SP:Q00005, SP:Q00007, and PID:190422; identified by sequence similarity; respiratory nitrate reductase subunit gamma 277514 narI 1164733 narI Brucella suis 1330 respiratory nitrate reductase subunit gamma NP_699491.1 276789 R 204722 CDS NP_699492.1 23500052 1164734 complement(277525..278232) 1 NC_004311.2 similar to GP:11344603, GB:L08239, and PID:950412; identified by sequence similarity; respiratory nitrate reductase subunit delta 278232 narJ 1164734 narJ Brucella suis 1330 respiratory nitrate reductase subunit delta NP_699492.1 277525 R 204722 CDS NP_699493.1 23500053 1164735 complement(278232..279770) 1 NC_004311.2 similar to GB:D90359, GB:M73442, GB:M73444, GB:X07024, SP:P21675, and PID:29733; identified by sequence similarity; respiratory nitrate reductase subunit beta 279770 narH 1164735 narH Brucella suis 1330 respiratory nitrate reductase subunit beta NP_699493.1 278232 R 204722 CDS NP_699494.1 23500054 1164736 complement(279767..283531) 1 NC_004311.2 similar to SP:P09152; identified by sequence similarity; respiratory nitrate reductase subunit alpha 283531 narG 1164736 narG Brucella suis 1330 respiratory nitrate reductase subunit alpha NP_699494.1 279767 R 204722 CDS NP_699495.1 23500055 1164737 complement(283555..286242) 1 NC_004311.2 similar to GP:14348603; identified by sequence similarity; nitrite extrusion protein 286242 narK 1164737 narK Brucella suis 1330 nitrite extrusion protein NP_699495.1 283555 R 204722 CDS NP_699496.1 23500056 1164738 286532..287242 1 NC_004311.2 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrB 287242 ftrB 1164738 ftrB Brucella suis 1330 transcriptional activator FtrB NP_699496.1 286532 D 204722 CDS NP_699497.1 23500057 1164739 complement(287297..288313) 1 NC_004311.2 similar to GP:5802909; identified by sequence similarity; sugar-binding protein 288313 1164739 BRA0302 Brucella suis 1330 sugar-binding protein NP_699497.1 287297 R 204722 CDS NP_699498.1 23500058 1164740 complement(288321..288437) 1 NC_004311.2 hypothetical protein 288437 1164740 BRA0303 Brucella suis 1330 hypothetical protein NP_699498.1 288321 R 204722 CDS NP_699499.1 23500059 1164741 288664..289929 1 NC_004311.2 similar to GP:5802910, and GP:2828820; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 289929 1164741 BRA0304 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_699499.1 288664 D 204722 CDS NP_699500.1 23500060 1164742 290006..290983 1 NC_004311.2 similar to GP:5802911, and GP:2828821; identified by sequence similarity; sugar ABC transporter permease 290983 1164742 BRA0305 Brucella suis 1330 sugar ABC transporter permease NP_699500.1 290006 D 204722 CDS NP_699501.1 23500061 1164743 290986..291813 1 NC_004311.2 similar to GP:5802912, and GP:13517311; identified by sequence similarity; sugar ABC transporter permease 291813 1164743 BRA0306 Brucella suis 1330 sugar ABC transporter permease NP_699501.1 290986 D 204722 CDS NP_699502.1 23500062 1164744 291820..292821 1 NC_004311.2 similar to GP:5802913; identified by sequence similarity; sugar ABC transporter ATP-binding protein 292821 1164744 BRA0307 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_699502.1 291820 D 204722 CDS NP_699503.1 23500063 1164745 292860..293669 1 NC_004311.2 similar to GP:5802914; identified by sequence similarity; hypothetical protein 293669 1164745 BRA0308 Brucella suis 1330 hypothetical protein NP_699503.1 292860 D 204722 CDS NP_699504.1 23500064 1164746 293678..294724 1 NC_004311.2 similar to GP:5802915; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 294724 1164746 BRA0309 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699504.1 293678 D 204722 CDS NP_699505.1 23500065 1164747 294961..295458 1 NC_004311.2 hypothetical protein 295458 1164747 BRA0310 Brucella suis 1330 hypothetical protein NP_699505.1 294961 D 204722 CDS NP_699506.1 23500066 1164748 295772..297400 1 NC_004311.2 similar to GP:15073164, and GP:12055084; identified by sequence similarity; transporter 297400 1164748 BRA0311 Brucella suis 1330 transporter NP_699506.1 295772 D 204722 CDS NP_699507.1 23500067 1164749 297387..297503 1 NC_004311.2 hypothetical protein 297503 1164749 BRA0312 Brucella suis 1330 hypothetical protein NP_699507.1 297387 D 204722 CDS NP_699508.1 23500068 1164750 complement(297557..297883) 1 NC_004311.2 hypothetical protein 297883 1164750 BRA0313 Brucella suis 1330 hypothetical protein NP_699508.1 297557 R 204722 CDS NP_699509.1 23500069 1164751 298077..298298 1 NC_004311.2 similar to GP:1800061; identified by sequence similarity; glutaredoxin-like protein nrdH 298298 nrdH 1164751 nrdH Brucella suis 1330 glutaredoxin-like protein nrdH NP_699509.1 298077 D 204722 CDS NP_699510.1 23500070 1164752 298312..298719 1 NC_004311.2 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 298719 nrdI 1164752 nrdI Brucella suis 1330 ribonucleotide reductase stimulatory protein NP_699510.1 298312 D 204722 CDS NP_699511.1 23500071 1164753 298770..300911 1 NC_004311.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 300911 nrdE 1164753 nrdE Brucella suis 1330 ribonucleotide-diphosphate reductase subunit alpha NP_699511.1 298770 D 204722 CDS NP_699512.1 23500072 1164754 300926..301915 1 NC_004311.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 301915 nrdF 1164754 nrdF Brucella suis 1330 ribonucleotide-diphosphate reductase subunit beta NP_699512.1 300926 D 204722 CDS NP_699513.1 23500073 1164755 complement(302085..302309) 1 NC_004311.2 hypothetical protein 302309 1164755 BRA0318 Brucella suis 1330 hypothetical protein NP_699513.1 302085 R 204722 CDS NP_699514.1 23500074 1164756 302443..302535 1 NC_004311.2 hypothetical protein 302535 1164756 BRA0319 Brucella suis 1330 hypothetical protein NP_699514.1 302443 D 204722 CDS NP_699515.1 23500075 1164757 302520..302651 1 NC_004311.2 hypothetical protein 302651 1164757 BRA0320 Brucella suis 1330 hypothetical protein NP_699515.1 302520 D 204722 CDS NP_699516.1 23500076 1164758 302781..303542 1 NC_004311.2 blocks the formation of polar Z-ring septums; septum formation inhibitor 303542 minC 1164758 minC Brucella suis 1330 septum formation inhibitor NP_699516.1 302781 D 204722 CDS NP_699517.1 23500077 1164759 303570..304385 1 NC_004311.2 similar to GP:15160138, and SP:P18197; identified by sequence similarity; septum site-determining protein MinD 304385 minD 1164759 minD Brucella suis 1330 septum site-determining protein MinD NP_699517.1 303570 D 204722 CDS NP_699518.1 23500078 1164760 304382..304654 1 NC_004311.2 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 304654 minE 1164760 minE Brucella suis 1330 cell division topological specificity factor MinE NP_699518.1 304382 D 204722 CDS NP_699519.1 23500079 1164761 304698..304865 1 NC_004311.2 hypothetical protein 304865 1164761 BRA0324 Brucella suis 1330 hypothetical protein NP_699519.1 304698 D 204722 CDS NP_699520.1 23500080 1164763 complement(305194..305586) 1 NC_004311.2 similar to GP:15159179, and GP:15159179; identified by sequence similarity; hypothetical protein 305586 1164763 BRA0325 Brucella suis 1330 hypothetical protein NP_699520.1 305194 R 204722 CDS NP_699521.1 23500081 1164764 305962..307008 1 NC_004311.2 similar to GP:14524112, and GP:17428750; identified by sequence similarity; spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein 307008 1164764 BRA0326 Brucella suis 1330 spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein NP_699521.1 305962 D 204722 CDS NP_699522.1 23500082 1164765 307082..308149 1 NC_004311.2 similar to GP:14524111; identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein 308149 1164765 BRA0327 Brucella suis 1330 spermidine/putrescine ABC transporter ATP-binding protein NP_699522.1 307082 D 204722 CDS NP_699523.1 23500083 1164766 308083..309321 1 NC_004311.2 similar to GP:14524110, and SP:P23860; identified by sequence similarity; spermidine/putrescine ABC transporter permease 309321 1164766 BRA0328 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_699523.1 308083 D 204722 CDS NP_699524.1 23500084 1164767 309324..310100 1 NC_004311.2 similar to GP:14524109, GB:X59932, SP:P41240, PID:30256, and PID:30315; identified by sequence similarity; spermidine/putrescine ABC transporter permease 310100 1164767 BRA0329 Brucella suis 1330 spermidine/putrescine ABC transporter permease NP_699524.1 309324 D 204722 CDS NP_699525.1 23500085 1164768 310412..310591 1 NC_004311.2 hypothetical protein 310591 1164768 BRA0330 Brucella suis 1330 hypothetical protein NP_699525.1 310412 D 204722 CDS NP_699526.1 23500086 1164769 310588..310812 1 NC_004311.2 hypothetical protein 310812 1164769 BRA0331 Brucella suis 1330 hypothetical protein NP_699526.1 310588 D 204722 CDS NP_699527.1 23500087 1164770 311049..311576 1 NC_004311.2 hypothetical protein 311576 1164770 BRA0332 Brucella suis 1330 hypothetical protein NP_699527.1 311049 D 204722 CDS NP_699528.1 23500088 1164771 complement(311718..312218) 1 NC_004311.2 hypothetical protein 312218 1164771 BRA0333 Brucella suis 1330 hypothetical protein NP_699528.1 311718 R 204722 CDS NP_699529.1 23500089 1164772 complement(312215..315439) 1 NC_004311.2 similar to GP:15141215; identified by sequence similarity; hydrophobe/amphiphile efflux-1 family protein 315439 1164772 BRA0334 Brucella suis 1330 hydrophobe/amphiphile efflux-1 family protein NP_699529.1 312215 R 204722 CDS NP_699530.1 23500090 1164773 complement(315443..316678) 1 NC_004311.2 similar to GP:14524048; identified by sequence similarity; HlyD family secretion protein 316678 1164773 BRA0335 Brucella suis 1330 HlyD family secretion protein NP_699530.1 315443 R 204722 CDS NP_699531.1 23500091 1164774 complement(316864..317397) 1 NC_004311.2 hypothetical protein 317397 1164774 BRA0336 Brucella suis 1330 hypothetical protein NP_699531.1 316864 R 204722 CDS NP_699532.1 23500092 1164775 complement(317472..317645) 1 NC_004311.2 hypothetical protein 317645 1164775 BRA0337 Brucella suis 1330 hypothetical protein NP_699532.1 317472 R 204722 CDS NP_699533.1 23500093 1164778 321132..322085 1 NC_004311.2 catalyzes the formation of glutamate from glutamine; glutaminase 322085 1164778 BRA0340 Brucella suis 1330 glutaminase NP_699533.1 321132 D 204722 CDS NP_699534.1 23500094 1164779 322233..322577 1 NC_004311.2 inactive form; acid-resistance protein 322577 hdeA 1164779 hdeA Brucella suis 1330 acid-resistance protein NP_699534.1 322233 D 204722 CDS NP_699535.1 23500095 1164780 322740..322838 1 NC_004311.2 hypothetical protein 322838 1164780 BRA0342 Brucella suis 1330 hypothetical protein NP_699535.1 322740 D 204722 CDS NP_699536.1 23500096 1164781 323090..323341 1 NC_004311.2 hypothetical protein 323341 1164781 BRA0343 Brucella suis 1330 hypothetical protein NP_699536.1 323090 D 204722 CDS NP_699537.1 23500097 1164782 complement(323418..325010) 1 NC_004311.2 similar to SP:P77473; identified by sequence similarity; diguanylate phosphodiesterase 325010 1164782 BRA0344 Brucella suis 1330 diguanylate phosphodiesterase NP_699537.1 323418 R 204722 CDS NP_699538.1 23500098 1164783 complement(325305..325571) 1 NC_004311.2 hypothetical protein 325571 1164783 BRA0345 Brucella suis 1330 hypothetical protein NP_699538.1 325305 R 204722 CDS NP_699539.1 23500099 1164784 325800..326687 1 NC_004311.2 identified by match to PFAM protein family HMM PF03466; LysR family transcriptional regulator 326687 1164784 BRA0346 Brucella suis 1330 LysR family transcriptional regulator NP_699539.1 325800 D 204722 CDS NP_699540.1 23500100 1164785 complement(326808..328223) 1 NC_004311.2 similar to GP:3510759; identified by sequence similarity; mannose-1-phosphate guanylyltransferase 328223 1164785 BRA0347 Brucella suis 1330 mannose-1-phosphate guanylyltransferase NP_699540.1 326808 R 204722 CDS NP_699541.1 23500101 1164786 complement(328220..329653) 1 NC_004311.2 similar to GP:2738951, SP:P06187, GB:K03551, GB:X52093, PID:154137, and PID:47739; identified by sequence similarity; phosphoglucomutase 329653 1164786 BRA0348 Brucella suis 1330 phosphoglucomutase NP_699541.1 328220 R 204722 CDS NP_699542.1 23500102 1164787 complement(329773..330879) 1 NC_004311.2 similar to GP:7799513, and GP:7799513; identified by sequence similarity; hypothetical protein 330879 1164787 BRA0349 Brucella suis 1330 hypothetical protein NP_699542.1 329773 R 204722 CDS NP_699543.1 23500103 1164788 complement(330903..332258) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03595; voltage gated chloride channel family protein 332258 1164788 BRA0350 Brucella suis 1330 voltage gated chloride channel family protein NP_699543.1 330903 R 204722 CDS NP_699544.1 23500104 1164789 complement(332317..332478) 1 NC_004311.2 hypothetical protein 332478 1164789 BRA0351 Brucella suis 1330 hypothetical protein NP_699544.1 332317 R 204722 CDS NP_699545.1 23500105 1164790 332453..333946 1 NC_004311.2 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 333946 guaB 1164790 guaB Brucella suis 1330 inosine 5'-monophosphate dehydrogenase NP_699545.1 332453 D 204722 CDS NP_699546.1 23500106 1164791 complement(334151..335224) 1 NC_004311.2 similar to GP:15140396; identified by sequence similarity; cytochrome c family protein 335224 1164791 BRA0353 Brucella suis 1330 cytochrome c family protein NP_699546.1 334151 R 204722 CDS NP_699547.1 23500107 1164792 complement(335293..336246) 1 NC_004311.2 similar to GP:4098965, and GP:4098965; identified by sequence similarity; transcriptional regulator OxyR 336246 oxyR 1164792 oxyR Brucella suis 1330 transcriptional regulator OxyR NP_699547.1 335293 R 204722 CDS NP_699548.1 23500108 1164793 336416..337915 1 NC_004311.2 similar to SP:Q59170, GB:L08666, SP:P45880, PID:190200, and PID:190201; identified by sequence similarity; catalase 337915 katA 1164793 katA Brucella suis 1330 catalase NP_699548.1 336416 D 204722 CDS NP_699549.1 23500109 1164794 338010..338219 1 NC_004311.2 similar to GP:9082308; identified by sequence similarity; hypothetical protein 338219 1164794 BRA0356 Brucella suis 1330 hypothetical protein NP_699549.1 338010 D 204722 CDS NP_699550.1 23500110 1164795 338248..338874 1 NC_004311.2 identified by match to PFAM protein family HMM PF02600; disulfide bond formation protein DsbB 338874 1164795 BRA0357 Brucella suis 1330 disulfide bond formation protein DsbB NP_699550.1 338248 D 204722 CDS NP_699551.1 23500111 1164796 339051..340340 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00563; sun protein 340340 1164796 BRA0358 Brucella suis 1330 sun protein NP_699551.1 339051 D 204722 CDS NP_699552.1 23500112 1164797 340631..341086 1 NC_004311.2 identified by match to PFAM protein family HMM PF02584; hypothetical protein 341086 1164797 BRA0359 Brucella suis 1330 hypothetical protein NP_699552.1 340631 D 204722 CDS NP_699553.1 23500113 1164798 341083..341715 1 NC_004311.2 Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 341715 1164798 BRA0360 Brucella suis 1330 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase NP_699553.1 341083 D 204722 CDS NP_699554.1 23500114 1164799 341824..343386 1 NC_004311.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 343386 guaA 1164799 guaA Brucella suis 1330 GMP synthase NP_699554.1 341824 D 204722 CDS NP_699555.1 23500115 1164800 343695..344903 1 NC_004311.2 identified by match to PFAM protein family HMM PF00589; phage integrase site specific recombinase 344903 1164800 BRA0362 Brucella suis 1330 phage integrase site specific recombinase NP_699555.1 343695 D 204722 CDS NP_699556.1 23500116 1164801 345188..345418 1 NC_004311.2 similar to SP:P37447, GB:X76902, and PID:436890; identified by sequence similarity; DNA-binding protein 345418 1164801 BRA0363 Brucella suis 1330 DNA-binding protein NP_699556.1 345188 D 204722 CDS NP_699557.1 23500117 1164802 345499..346557 1 NC_004311.2 similar to GP:8117186, and GP:8117186; identified by sequence similarity; repA-like protein 346557 1164802 BRA0364 Brucella suis 1330 repA-like protein NP_699557.1 345499 D 204722 CDS NP_699558.1 23500118 1164803 complement(347606..347932) 1 NC_004311.2 hypothetical protein 347932 1164803 BRA0365 Brucella suis 1330 hypothetical protein NP_699558.1 347606 R 204722 CDS NP_699559.1 23500119 1164804 complement(347935..349578) 1 NC_004311.2 similar to GB:X72841, SP:P31149, SP:Q09028, SP:Q16576, PID:1016273, and PID:297904; identified by sequence similarity; trbL protein 349578 1164804 BRA0366 Brucella suis 1330 trbL protein NP_699559.1 347935 R 204722 CDS NP_699560.1 23500120 1164805 complement(349581..349763) 1 NC_004311.2 hypothetical protein 349763 1164805 BRA0367 Brucella suis 1330 hypothetical protein NP_699560.1 349581 R 204722 CDS NP_699561.1 23500121 1164806 complement(349766..350557) 1 NC_004311.2 similar to SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, PID:43821, SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, and PID:43821; identified by sequence similarity; trbJ protein 350557 1164806 BRA0368 Brucella suis 1330 trbJ protein NP_699561.1 349766 R 204722 CDS NP_699562.1 23500122 1164807 350655..350807 1 NC_004311.2 hypothetical protein 350807 1164807 BRA0369 Brucella suis 1330 hypothetical protein NP_699562.1 350655 D 204722 CDS NP_699563.1 23500123 1164808 complement(350825..351049) 1 NC_004311.2 hypothetical protein 351049 1164808 BRA0370 Brucella suis 1330 hypothetical protein NP_699563.1 350825 R 204722 CDS NP_699564.1 23500124 1164809 complement(351052..351270) 1 NC_004311.2 similar to GP:14523605, GB:L33243, GB:L43601, GB:L43602, GB:L43604, GB:L43605, GB:L43610, GB:L43617, GB:L43618, SP:P98161, PID:799335, PID:903758, and PID:904223; identified by sequence similarity; traC protein 351270 1164809 BRA0371 Brucella suis 1330 traC protein NP_699564.1 351052 R 204722 CDS NP_699565.1 23500125 1164810 351940..352320 1 NC_004311.2 similar to SP:P17909; identified by sequence similarity; traJ protein 352320 1164810 BRA0372 Brucella suis 1330 traJ protein NP_699565.1 351940 D 204722 CDS NP_699566.1 23500126 1164811 352317..354269 1 NC_004311.2 similar to GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, PID:587442, GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, and PID:587442; identified by sequence similarity; traI protein 354269 1164811 BRA0373 Brucella suis 1330 traI protein NP_699566.1 352317 D 204722 CDS NP_699567.1 23500127 1164812 complement(354676..356100) 1 NC_004311.2 hypothetical protein 356100 1164812 BRA0374 Brucella suis 1330 hypothetical protein NP_699567.1 354676 R 204722 CDS NP_699568.1 23500128 1164813 complement(356254..357279) 1 NC_004311.2 hypothetical protein 357279 1164813 BRA0375 Brucella suis 1330 hypothetical protein NP_699568.1 356254 R 204722 CDS NP_699569.1 23500129 1164814 complement(357313..358038) 1 NC_004311.2 hypothetical protein 358038 1164814 BRA0376 Brucella suis 1330 hypothetical protein NP_699569.1 357313 R 204722 CDS NP_699570.1 23500130 1164815 complement(358217..359938) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00634; hypothetical protein 359938 1164815 BRA0377 Brucella suis 1330 hypothetical protein NP_699570.1 358217 R 204722 CDS NP_699571.1 23500131 1164816 complement(360180..361004) 1 NC_004311.2 hypothetical protein 361004 1164816 BRA0378 Brucella suis 1330 hypothetical protein NP_699571.1 360180 R 204722 CDS NP_699572.1 23500132 1164817 complement(361149..361343) 1 NC_004311.2 similar to GB:M23326, GB:X15261, GB:X13954, PID:1049195, PID:2358067, PID:312412, PID:37046, PID:37048, PID:37298, PID:37324, and PID:540457; identified by sequence similarity; DNA-damage-inducible protein J 361343 1164817 BRA0379 Brucella suis 1330 DNA-damage-inducible protein J NP_699572.1 361149 R 204722 CDS NP_699573.1 23500133 1164818 361753..361938 1 NC_004311.2 hypothetical protein 361938 1164818 BRA0380 Brucella suis 1330 hypothetical protein NP_699573.1 361753 D 204722 CDS NP_699574.1 23500134 1164819 362050..362598 1 NC_004311.2 similar to GB:D14695, and PID:285961; identified by sequence similarity; membrane antigen 362598 1164819 BRA0381 Brucella suis 1330 membrane antigen NP_699574.1 362050 D 204722 CDS NP_699575.1 23500135 1164820 362602..363000 1 NC_004311.2 similar to GB:M20730, SP:P16534, GB:M24197, PID:150496, and PID:150515; identified by sequence similarity; hypothetical protein 363000 1164820 BRA0382 Brucella suis 1330 hypothetical protein NP_699575.1 362602 D 204722 CDS NP_699576.1 23500136 1164821 363007..363843 1 NC_004311.2 similar to GP:6469262, and GP:6469262; identified by sequence similarity; FTR1 family iron permease 363843 1164821 BRA0383 Brucella suis 1330 FTR1 family iron permease NP_699576.1 363007 D 204722 CDS NP_699577.1 23500137 1164822 363804..365237 1 NC_004311.2 similar to SP:P35097, and GB:Z47792; identified by sequence similarity; hypothetical protein 365237 1164822 BRA0384 Brucella suis 1330 hypothetical protein NP_699577.1 363804 D 204722 CDS NP_699578.1 23500138 1164823 complement(365495..367864) 1 NC_004311.2 similar to SP:Q9AEM9; identified by sequence similarity; phosphoketolase 367864 xfp 1164823 xfp Brucella suis 1330 phosphoketolase NP_699578.1 365495 R 204722 CDS NP_699579.1 23500139 1164824 complement(367894..369099) 1 NC_004311.2 Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase 369099 1164824 BRA0386 Brucella suis 1330 acetate kinase NP_699579.1 367894 R 204722 CDS NP_699580.1 23500140 1164825 369338..369499 1 NC_004311.2 hypothetical protein 369499 1164825 BRA0387 Brucella suis 1330 hypothetical protein NP_699580.1 369338 D 204722 CDS NP_699581.1 23500141 1164826 369542..370705 1 NC_004311.2 identified by match to PFAM protein family HMM PF00067; heme-thiolate monooxygenase 370705 1164826 BRA0388 Brucella suis 1330 heme-thiolate monooxygenase NP_699581.1 369542 D 204722 CDS NP_699582.1 23500142 1164827 complement(370776..371453) 1 NC_004311.2 similar to GP:14524114; identified by sequence similarity; GntR family transcriptional regulator 371453 1164827 BRA0389 Brucella suis 1330 GntR family transcriptional regulator NP_699582.1 370776 R 204722 CDS NP_699583.1 23500143 1164828 371511..371732 1 NC_004311.2 hypothetical protein 371732 1164828 BRA0390 Brucella suis 1330 hypothetical protein NP_699583.1 371511 D 204722 CDS NP_699584.1 23500144 1164829 371725..372732 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00692; alcohol dehydrogenase 372732 1164829 BRA0391 Brucella suis 1330 alcohol dehydrogenase NP_699584.1 371725 D 204722 CDS NP_699585.1 23500145 1164830 372816..374027 1 NC_004311.2 similar to SP:P04816, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 374027 1164830 BRA0392 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_699585.1 372816 D 204722 CDS NP_699586.1 23500146 1164831 374076..374960 1 NC_004311.2 similar to GP:19715091; identified by sequence similarity; branched-chain amino acid ABC transporter permease 374960 1164831 BRA0393 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699586.1 374076 D 204722 CDS NP_699587.1 23500147 1164833 376794..377498 1 NC_004311.2 similar to SP:P22731; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 377498 1164833 BRA0395 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_699587.1 376794 D 204722 CDS NP_699588.1 23500148 1164834 377501..378298 1 NC_004311.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 378298 fabG 1164834 fabG Brucella suis 1330 3-ketoacyl-ACP reductase NP_699588.1 377501 D 204722 CDS NP_699589.1 23500149 1164835 378303..379121 1 NC_004311.2 identified by match to PFAM protein family HMM PF00745; shikimate dehydrogenase 379121 1164835 BRA0397 Brucella suis 1330 shikimate dehydrogenase NP_699589.1 378303 D 204722 CDS NP_699590.1 23500150 1164836 379126..380760 1 NC_004311.2 identified by match to PFAM protein family HMM PF00070; GMC family oxidoreductase 380760 1164836 BRA0398 Brucella suis 1330 GMC family oxidoreductase NP_699590.1 379126 D 204722 CDS NP_699591.1 23500151 1164837 380785..382215 1 NC_004311.2 similar to GP:15159844; identified by sequence similarity; aldehyde dehydrogenase 382215 1164837 BRA0399 Brucella suis 1330 aldehyde dehydrogenase NP_699591.1 380785 D 204722 CDS NP_699592.1 23500152 1164838 382307..383470 1 NC_004311.2 similar to SP:P02917, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 383470 1164838 BRA0400 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_699592.1 382307 D 204722 CDS NP_699593.1 23500153 1164839 383533..384660 1 NC_004311.2 similar to GP:15075876; identified by sequence similarity; alcohol dehydrogenase 384660 1164839 BRA0401 Brucella suis 1330 alcohol dehydrogenase NP_699593.1 383533 D 204722 CDS NP_699594.1 23500154 1164840 384865..385860 1 NC_004311.2 similar to SP:P49307; identified by sequence similarity; oxidoreductase 385860 1164840 BRA0402 Brucella suis 1330 oxidoreductase NP_699594.1 384865 D 204722 CDS NP_699595.1 23500155 1164841 385848..387134 1 NC_004311.2 identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 387134 1164841 BRA0403 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699595.1 385848 D 204722 CDS NP_699596.1 23500156 1164842 complement(386912..387865) 1 NC_004311.2 similar to SP:P24137, GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; peptide ABC transporter ATP-binding protein 387865 1164842 BRA0404 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_699596.1 386912 R 204722 CDS NP_699597.1 23500157 1164843 complement(387862..388878) 1 NC_004311.2 similar to GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; peptide ABC transporter ATP-binding protein 388878 1164843 BRA0405 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_699597.1 387862 R 204722 CDS NP_699598.1 23500158 1164844 complement(388889..389806) 1 NC_004311.2 similar to GP:12541464; identified by sequence similarity; dihydrodipicolinate synthase 389806 1164844 BRA0406 Brucella suis 1330 dihydrodipicolinate synthase NP_699598.1 388889 R 204722 CDS NP_699599.1 23500159 1164845 complement(389826..390734) 1 NC_004311.2 similar to GP:15160372; identified by sequence similarity; peptide ABC transporter permease 390734 1164845 BRA0407 Brucella suis 1330 peptide ABC transporter permease NP_699599.1 389826 R 204722 CDS NP_699600.1 23500160 1164846 complement(390700..391659) 1 NC_004311.2 similar to GB:X07820, SP:P09238, and PID:36629; identified by sequence similarity; peptide ABC transporter permease 391659 1164846 BRA0408 Brucella suis 1330 peptide ABC transporter permease NP_699600.1 390700 R 204722 CDS NP_699601.1 23500161 1164847 complement(391759..393342) 1 NC_004311.2 similar to GP:15158790, and GP:6969001; identified by sequence similarity; peptide ABC transporter substrate-binding protein 393342 1164847 BRA0409 Brucella suis 1330 peptide ABC transporter substrate-binding protein NP_699601.1 391759 R 204722 CDS NP_699602.1 23500162 1164848 complement(393339..394067) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 394067 1164848 BRA0410 Brucella suis 1330 GntR family transcriptional regulator NP_699602.1 393339 R 204722 CDS NP_699603.1 23500163 1164849 394227..395804 1 NC_004311.2 identified by match to PFAM protein family HMM PF00218; ROK family protein 395804 1164849 BRA0411 Brucella suis 1330 ROK family protein NP_699603.1 394227 D 204722 CDS NP_699604.1 23500164 1164851 397094..397369 1 NC_004311.2 hypothetical protein 397369 1164851 BRA0413 Brucella suis 1330 hypothetical protein NP_699604.1 397094 D 204722 CDS NP_699605.1 23500165 1164852 complement(397370..398128) 1 NC_004311.2 similar to GP:5478244, and GP:5478244; identified by sequence similarity; Crp/Fnr family transcriptional regulator 398128 1164852 BRA0414 Brucella suis 1330 Crp/Fnr family transcriptional regulator NP_699605.1 397370 R 204722 CDS NP_699606.1 23500166 1164853 398491..399258 1 NC_004311.2 similar to GP:5478243, and GP:5478243; identified by sequence similarity; LuxR family transcriptional regulator 399258 1164853 BRA0415 Brucella suis 1330 LuxR family transcriptional regulator NP_699606.1 398491 D 204722 CDS NP_699607.1 23500167 1164854 399295..401484 1 NC_004311.2 similar to GP:5478242, and GP:5478242; identified by sequence similarity; exopolysaccharide biosynthesis protein Bme12 401484 1164854 BRA0416 Brucella suis 1330 exopolysaccharide biosynthesis protein Bme12 NP_699607.1 399295 D 204722 CDS NP_699608.1 23500168 1164855 401494..402741 1 NC_004311.2 similar to GP:5478241, GP:5478241, GB:M83667, SP:P49716, and PID:189176; identified by sequence similarity; exopolysaccharide biosynthesis protein Bme11 402741 1164855 BRA0417 Brucella suis 1330 exopolysaccharide biosynthesis protein Bme11 NP_699608.1 401494 D 204722 CDS NP_699609.1 23500169 1164856 complement(402846..403826) 1 NC_004311.2 similar to GP:5478240; identified by sequence similarity; fucose synthetase 403826 1164856 BRA0418 Brucella suis 1330 fucose synthetase NP_699609.1 402846 R 204722 CDS NP_699610.1 23500170 1164857 complement(403810..404880) 1 NC_004311.2 similar to GP:5478239, and SP:P15527; identified by sequence similarity; GDP-mannose 4,6-dehydratase Bme9 404880 1164857 BRA0419 Brucella suis 1330 GDP-mannose 4,6-dehydratase Bme9 NP_699610.1 403810 R 204722 CDS NP_699611.1 23500171 1164859 406415..407650 1 NC_004311.2 similar to GP:5478237, and GP:5478237; identified by sequence similarity; group 1 glycosyl transferase 407650 1164859 BRA0421 Brucella suis 1330 group 1 glycosyl transferase NP_699611.1 406415 D 204722 CDS NP_699612.1 23500172 1164860 407647..408843 1 NC_004311.2 similar to GP:5478236, and GP:5478236; identified by sequence similarity; group 1 glycosyl transferase 408843 1164860 BRA0422 Brucella suis 1330 group 1 glycosyl transferase NP_699612.1 407647 D 204722 CDS NP_699613.1 23500173 1164861 complement(408914..409636) 1 NC_004311.2 similar to GB:X70959, SP:P42459, PID:452384, GB:X70959, SP:P42459, and PID:452384; identified by sequence similarity; hypothetical protein 409636 omp31-2 1164861 omp31-2 Brucella suis 1330 hypothetical protein NP_699613.1 408914 R 204722 CDS NP_699614.1 23500174 1164862 complement(410033..410647) 1 NC_004311.2 similar to GP:5478235; identified by sequence similarity; acetyltransferase 410647 1164862 BRA0424 Brucella suis 1330 acetyltransferase NP_699614.1 410033 R 204722 CDS NP_699615.1 23500175 1164864 complement(411918..412535) 1 NC_004311.2 similar to GP:5478233, and GP:5478233; identified by sequence similarity; Bme2 protein 412535 1164864 BRA0426 Brucella suis 1330 Bme2 protein NP_699615.1 411918 R 204722 CDS NP_699616.1 23500176 1164865 complement(412532..413413) 1 NC_004311.2 similar to GP:5478232; identified by sequence similarity; glycosyl transferase group 2 family protein 413413 1164865 BRA0427 Brucella suis 1330 glycosyl transferase group 2 family protein NP_699616.1 412532 R 204722 CDS NP_699617.1 23500177 1164866 complement(413410..414537) 1 NC_004311.2 similar to GP:15158359, GB:J00109, GB:K03512, GB:M28637, GB:A15601, GB:K03513, GB:A11954, GB:X15943, SP:P01258, SP:P06881, PID:1340176, PID:179799, PID:179828, PID:180466, PID:296638, and PID:457134; identified by sequence similarity; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase 414537 1164866 BRA0428 Brucella suis 1330 undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase NP_699617.1 413410 R 204722 CDS NP_699618.1 23500178 1164867 414830..416323 1 NC_004311.2 similar to GP:15158365; identified by sequence similarity; polysaccharide biosynthesis protein 416323 1164867 BRA0429 Brucella suis 1330 polysaccharide biosynthesis protein NP_699618.1 414830 D 204722 CDS NP_699619.1 23500179 1164868 416339..417352 1 NC_004311.2 similar to GP:15158366; identified by sequence similarity; glycosyl transferase group 2 family protein 417352 1164868 BRA0430 Brucella suis 1330 glycosyl transferase group 2 family protein NP_699619.1 416339 D 204722 CDS NP_699620.1 23500180 1164869 complement(417308..418549) 1 NC_004311.2 similar to GP:15158364, and GP:15158364; identified by sequence similarity; hypothetical protein 418549 1164869 BRA0431 Brucella suis 1330 hypothetical protein NP_699620.1 417308 R 204722 CDS NP_699621.1 23500181 1164870 418666..420045 1 NC_004311.2 similar to GP:15158361; identified by sequence similarity; group 1 glycosyl transferase 420045 1164870 BRA0432 Brucella suis 1330 group 1 glycosyl transferase NP_699621.1 418666 D 204722 CDS NP_699622.1 23500182 1164871 420083..421444 1 NC_004311.2 catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; glutamate-1-semialdehyde 2,1-aminomutase 421444 1164871 BRA0433 Brucella suis 1330 glutamate-1-semialdehyde 2,1-aminomutase NP_699622.1 420083 D 204722 CDS NP_699623.1 23500183 1164872 421423..422757 1 NC_004311.2 similar to GP:15158360, and GP:15158360; identified by sequence similarity; hypothetical protein 422757 1164872 BRA0434 Brucella suis 1330 hypothetical protein NP_699623.1 421423 D 204722 CDS NP_699624.1 23500184 1164873 422878..423939 1 NC_004311.2 similar to GP:15158370; identified by sequence similarity; epimerase 423939 1164873 BRA0435 Brucella suis 1330 epimerase NP_699624.1 422878 D 204722 CDS NP_699625.1 23500185 1164874 423939..425291 1 NC_004311.2 similar to GP:15158371, and GP:15158371; identified by sequence similarity; hypothetical protein 425291 1164874 BRA0436 Brucella suis 1330 hypothetical protein NP_699625.1 423939 D 204722 CDS NP_699626.1 23500186 1164875 complement(425254..425778) 1 NC_004311.2 similar to SP:P29202, and PID:148782; identified by sequence similarity; dTDP-4-dehydrorhamnose 3,5-epimerase 425778 rfbC 1164875 rfbC Brucella suis 1330 dTDP-4-dehydrorhamnose 3,5-epimerase NP_699626.1 425254 R 204722 CDS NP_699627.1 23500187 1164876 426099..427400 1 NC_004311.2 similar to GP:15158375; identified by sequence similarity; methyltransferase 427400 1164876 BRA0438 Brucella suis 1330 methyltransferase NP_699627.1 426099 D 204722 CDS NP_699628.1 23500188 1164877 427403..428212 1 NC_004311.2 similar to GP:15158376; identified by sequence similarity; nucleotidyltransferase 428212 1164877 BRA0439 Brucella suis 1330 nucleotidyltransferase NP_699628.1 427403 D 204722 CDS NP_699629.1 23500189 1164878 428209..428865 1 NC_004311.2 similar to GP:15158377, and GP:6066675; identified by sequence similarity; hypothetical protein 428865 1164878 BRA0440 Brucella suis 1330 hypothetical protein NP_699629.1 428209 D 204722 CDS NP_699630.1 23500190 1164879 428933..429064 1 NC_004311.2 hypothetical protein 429064 1164879 BRA0441 Brucella suis 1330 hypothetical protein NP_699630.1 428933 D 204722 CDS NP_699631.1 23500191 1164880 complement(429061..430341) 1 NC_004311.2 similar to GP:15160336; identified by sequence similarity; uracil-xanthine permease 430341 1164880 BRA0442 Brucella suis 1330 uracil-xanthine permease NP_699631.1 429061 R 204722 CDS NP_699632.1 23500192 1164881 complement(430458..431954) 1 NC_004311.2 similar to SP:O66131; identified by sequence similarity; glycerol kinase 431954 glpK 1164881 glpK Brucella suis 1330 glycerol kinase NP_699632.1 430458 R 204722 CDS NP_699633.1 23500193 1164882 complement(432081..433382) 1 NC_004311.2 identified by match to PFAM protein family HMM PF04024; major facilitator family transporter 433382 1164882 BRA0444 Brucella suis 1330 major facilitator family transporter NP_699633.1 432081 R 204722 CDS NP_699634.1 23500194 1164883 433487..434374 1 NC_004311.2 similar to GP:4106617; identified by sequence similarity; LysR family transcriptional regulator 434374 1164883 BRA0445 Brucella suis 1330 LysR family transcriptional regulator NP_699634.1 433487 D 204722 CDS NP_699635.1 23500195 1164884 434459..434899 1 NC_004311.2 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 434899 1164884 BRA0446 Brucella suis 1330 methionine sulfoxide reductase B NP_699635.1 434459 D 204722 CDS NP_699636.1 23500196 1164885 complement(434900..436027) 1 NC_004311.2 similar to GP:15159873, and SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase 436027 1164885 BRA0447 Brucella suis 1330 acyl-CoA dehydrogenase NP_699636.1 434900 R 204722 CDS NP_699637.1 23500197 1164886 complement(436027..437217) 1 NC_004311.2 similar to GB:X03342, SP:P02433, and PID:36132; identified by sequence similarity; acetyl-CoA acetyltransferase 437217 phbA-2 1164886 phbA-2 Brucella suis 1330 acetyl-CoA acetyltransferase NP_699637.1 436027 R 204722 CDS NP_699638.1 23500198 1164887 complement(437286..438053) 1 NC_004311.2 similar to GP:9948613, GB:M29297, and SP:P20189; identified by sequence similarity; 3-hydroxyacyl-CoA dehydrogenase 438053 1164887 BRA0449 Brucella suis 1330 3-hydroxyacyl-CoA dehydrogenase NP_699638.1 437286 R 204722 CDS NP_699639.1 23500199 1164888 complement(438066..439736) 1 NC_004311.2 similar to GB:M25667, GB:S66533, GB:S66534, GB:S66541, SP:P17677, and PID:182970; identified by sequence similarity; acetyl-CoA synthetase 439736 1164888 BRA0450 Brucella suis 1330 acetyl-CoA synthetase NP_699639.1 438066 R 204722 CDS NP_699640.1 23500200 1164889 439863..440846 1 NC_004311.2 similar to GP:14523919; identified by sequence similarity; AraC family transcriptional regulator 440846 1164889 BRA0451 Brucella suis 1330 AraC family transcriptional regulator NP_699640.1 439863 D 204722 CDS NP_699641.1 23500201 1164890 440894..441073 1 NC_004311.2 hypothetical protein 441073 1164890 BRA0452 Brucella suis 1330 hypothetical protein NP_699641.1 440894 D 204722 CDS NP_699642.1 23500202 1164891 441070..442308 1 NC_004311.2 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 442308 serA-2 1164891 serA-2 Brucella suis 1330 D-3-phosphoglycerate dehydrogenase NP_699642.1 441070 D 204722 CDS NP_699643.1 23500203 1164892 complement(442361..442855) 1 NC_004311.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 442855 def 1164892 def Brucella suis 1330 peptide deformylase NP_699643.1 442361 R 204722 CDS NP_699644.1 23500204 1164893 complement(443601..444542) 1 NC_004311.2 similar to GB:Z29635, SP:P46374, PID:455002, GB:Z29635, SP:P46374, and PID:455002; identified by sequence similarity; hypothetical protein 444542 1164893 BRA0455 Brucella suis 1330 hypothetical protein NP_699644.1 443601 R 204722 CDS NP_699645.1 23500205 1164894 444855..445178 1 NC_004311.2 identified by match to PFAM protein family HMM PF01022; ArsR family transcriptional regulator 445178 1164894 BRA0456 Brucella suis 1330 ArsR family transcriptional regulator NP_699645.1 444855 D 204722 CDS NP_699646.1 23500206 1164895 445178..445585 1 NC_004311.2 similar to GP:14523677, and GP:14523677; identified by sequence similarity; hypothetical protein 445585 1164895 BRA0457 Brucella suis 1330 hypothetical protein NP_699646.1 445178 D 204722 CDS NP_699647.1 23500207 1164896 445582..446019 1 NC_004311.2 hypothetical protein 446019 1164896 BRA0458 Brucella suis 1330 hypothetical protein NP_699647.1 445582 D 204722 CDS NP_699648.1 23500208 1164897 complement(446042..446749) 1 NC_004311.2 similar to GP:14524042; identified by sequence similarity; GntR family transcriptional regulator 446749 1164897 BRA0459 Brucella suis 1330 GntR family transcriptional regulator NP_699648.1 446042 R 204722 CDS NP_699649.1 23500209 1164898 446995..448053 1 NC_004311.2 identified by match to PFAM protein family HMM PF01594; hypothetical protein 448053 1164898 BRA0460 Brucella suis 1330 hypothetical protein NP_699649.1 446995 D 204722 CDS NP_699650.1 23500210 1164899 448181..448369 1 NC_004311.2 hypothetical protein 448369 1164899 BRA0461 Brucella suis 1330 hypothetical protein NP_699650.1 448181 D 204722 CDS NP_699651.1 23500211 1164900 448672..449391 1 NC_004311.2 identified by match to PFAM protein family HMM PF03130; TetR family transcriptional regulator 449391 1164900 BRA0462 Brucella suis 1330 TetR family transcriptional regulator NP_699651.1 448672 D 204722 CDS NP_699652.1 23500212 1164901 449396..450340 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 450340 1164901 BRA0463 Brucella suis 1330 HlyD family secretion protein NP_699652.1 449396 D 204722 CDS NP_699653.1 23500213 1164903 451261..452394 1 NC_004311.2 similar to GP:17427173; identified by sequence similarity; ABC transporter permease 452394 1164903 BRA0465 Brucella suis 1330 ABC transporter permease NP_699653.1 451261 D 204722 CDS NP_699654.1 23500214 1164904 452432..452830 1 NC_004311.2 similar to GP:15158870, and GP:15074195; identified by sequence similarity; hypothetical protein 452830 1164904 BRA0466 Brucella suis 1330 hypothetical protein NP_699654.1 452432 D 204722 CDS NP_699655.1 23500215 1164905 complement(452837..453655) 1 NC_004311.2 similar to GP:13021750, and SP:Q47539; identified by sequence similarity; taurine ABC transporter permease 453655 1164905 BRA0467 Brucella suis 1330 taurine ABC transporter permease NP_699655.1 452837 R 204722 CDS NP_699656.1 23500216 1164906 complement(453648..454415) 1 NC_004311.2 similar to SP:P37338, GB:U00096, and PID:1789018; identified by sequence similarity; ABC transporter ATP-binding protein 454415 1164906 BRA0468 Brucella suis 1330 ABC transporter ATP-binding protein NP_699656.1 453648 R 204722 CDS NP_699657.1 23500217 1164907 complement(454461..455483) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00497; ABC transporter periplasmic substrate-binding protein 455483 1164907 BRA0469 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_699657.1 454461 R 204722 CDS NP_699658.1 23500218 1164909 456341..457972 1 NC_004311.2 similar to GP:15074065; identified by sequence similarity; transporter 457972 1164909 BRA0471 Brucella suis 1330 transporter NP_699658.1 456341 D 204722 CDS NP_699659.1 23500219 1164910 457997..459046 1 NC_004311.2 similar to GP:15156118; identified by sequence similarity; HlyD family secretion protein 459046 1164910 BRA0472 Brucella suis 1330 HlyD family secretion protein NP_699659.1 457997 D 204722 CDS NP_699660.1 23500220 1164911 complement(459118..460542) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01386; osmolarity sensor protein EnvZ 460542 1164911 BRA0473 Brucella suis 1330 osmolarity sensor protein EnvZ NP_699660.1 459118 R 204722 CDS NP_699661.1 23500221 1164912 complement(460539..461255) 1 NC_004311.2 similar to GP:14023190; identified by sequence similarity; transcriptional regulatory protein OmpR 461255 1164912 BRA0474 Brucella suis 1330 transcriptional regulatory protein OmpR NP_699661.1 460539 R 204722 CDS NP_699662.1 23500222 1164913 complement(461449..461595) 1 NC_004311.2 hypothetical protein 461595 1164913 BRA0475 Brucella suis 1330 hypothetical protein NP_699662.1 461449 R 204722 CDS NP_699663.1 23500223 1164914 461579..461944 1 NC_004311.2 hypothetical protein 461944 1164914 BRA0476 Brucella suis 1330 hypothetical protein NP_699663.1 461579 D 204722 CDS NP_699664.1 23500224 1164915 461956..462108 1 NC_004311.2 hypothetical protein 462108 1164915 BRA0477 Brucella suis 1330 hypothetical protein NP_699664.1 461956 D 204722 CDS NP_699665.1 23500225 1164916 462368..462718 1 NC_004311.2 similar to GP:14026911; identified by sequence similarity; hypothetical protein 462718 1164916 BRA0478 Brucella suis 1330 hypothetical protein NP_699665.1 462368 D 204722 CDS NP_699666.1 23500226 1164917 complement(462841..464037) 1 NC_004311.2 similar to GP:15075101; identified by sequence similarity; pyridine nucleotide-disulfide oxidoreductase 464037 1164917 BRA0479 Brucella suis 1330 pyridine nucleotide-disulfide oxidoreductase NP_699666.1 462841 R 204722 CDS NP_699667.1 23500227 1164918 complement(464120..464569) 1 NC_004311.2 similar to GP:15155841; identified by sequence similarity; MarR family transcriptional regulator 464569 1164918 BRA0480 Brucella suis 1330 MarR family transcriptional regulator NP_699667.1 464120 R 204722 CDS NP_699668.1 23500228 1164919 464851..465630 1 NC_004311.2 similar to GP:15075862; identified by sequence similarity; glyoxalase 465630 1164919 BRA0481 Brucella suis 1330 glyoxalase NP_699668.1 464851 D 204722 CDS NP_699669.1 23500229 1164920 complement(465694..465864) 1 NC_004311.2 hypothetical protein 465864 1164920 BRA0482 Brucella suis 1330 hypothetical protein NP_699669.1 465694 R 204722 CDS NP_699670.1 23500230 1164921 complement(465911..467344) 1 NC_004311.2 similar to GP:15074955; identified by sequence similarity; amino acid carrier protein 467344 1164921 BRA0483 Brucella suis 1330 amino acid carrier protein NP_699670.1 465911 R 204722 CDS NP_699671.1 23500231 1164922 complement(467328..467627) 1 NC_004311.2 hypothetical protein 467627 1164922 BRA0485 Brucella suis 1330 hypothetical protein NP_699671.1 467328 R 204722 CDS NP_699672.1 23500232 1164923 467331..467615 1 NC_004311.2 hypothetical protein 467615 1164923 BRA0484 Brucella suis 1330 hypothetical protein NP_699672.1 467331 D 204722 CDS NP_699673.1 23500233 1164924 467772..468692 1 NC_004311.2 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 468692 metA 1164924 metA Brucella suis 1330 homoserine O-succinyltransferase NP_699673.1 467772 D 204722 CDS NP_699674.1 23500234 1164925 complement(468760..469749) 1 NC_004311.2 similar to GP:15140555; identified by sequence similarity; glycosyl hydrolase 469749 1164925 BRA0487 Brucella suis 1330 glycosyl hydrolase NP_699674.1 468760 R 204722 CDS NP_699675.1 23500235 1164926 complement(470102..471082) 1 NC_004311.2 FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 471082 1164926 BRA0488 Brucella suis 1330 3-oxoacyl-ACP synthase NP_699675.1 470102 R 204722 CDS NP_699676.1 23500236 1164927 complement(471079..472353) 1 NC_004311.2 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 472353 bioA 1164927 bioA Brucella suis 1330 adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_699676.1 471079 R 204722 CDS NP_699677.1 23500237 1164928 complement(472350..472988) 1 NC_004311.2 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase 472988 bioD 1164928 bioD Brucella suis 1330 dithiobiotin synthetase NP_699677.1 472350 R 204722 CDS NP_699678.1 23500238 1164929 complement(472985..474121) 1 NC_004311.2 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase 474121 bioF 1164929 bioF Brucella suis 1330 8-amino-7-oxononanoate synthase NP_699678.1 472985 R 204722 CDS NP_699679.1 23500239 1164930 complement(474118..475104) 1 NC_004311.2 similar to GB:L05091, GB:U58682, SP:P25112, PID:1518637, and PID:337403; identified by sequence similarity; biotin synthase 475104 bioB 1164930 bioB Brucella suis 1330 biotin synthase NP_699679.1 474118 R 204722 CDS NP_699680.1 23500240 1164931 475376..475537 1 NC_004311.2 hypothetical protein 475537 1164931 BRA0493 Brucella suis 1330 hypothetical protein NP_699680.1 475376 D 204722 CDS NP_699681.1 23500241 1164932 complement(475515..475796) 1 NC_004311.2 hypothetical protein 475796 1164932 BRA0494 Brucella suis 1330 hypothetical protein NP_699681.1 475515 R 204722 CDS NP_699682.1 23500242 1164933 complement(475893..476006) 1 NC_004311.2 hypothetical protein 476006 1164933 BRA0495 Brucella suis 1330 hypothetical protein NP_699682.1 475893 R 204722 CDS NP_699683.1 23500243 1164934 476059..476577 1 NC_004311.2 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 476577 mogA 1164934 mogA Brucella suis 1330 molybdenum cofactor biosynthesis protein MogA NP_699683.1 476059 D 204722 CDS NP_699684.1 23500244 1164935 complement(476629..477228) 1 NC_004311.2 hypothetical protein 477228 1164935 BRA0497 Brucella suis 1330 hypothetical protein NP_699684.1 476629 R 204722 CDS NP_699685.1 23500245 1164936 477295..477414 1 NC_004311.2 hypothetical protein 477414 1164936 BRA0498 Brucella suis 1330 hypothetical protein NP_699685.1 477295 D 204722 CDS NP_699686.1 23500246 1164937 477552..478880 1 NC_004311.2 identified by match to PFAM protein family HMM PF00070; hypothetical protein 478880 1164937 BRA0499 Brucella suis 1330 hypothetical protein NP_699686.1 477552 D 204722 CDS NP_699687.1 23500247 1164938 479321..482239 1 NC_004311.2 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; monovalent cation/H+ antiporter subunit A 482239 1164938 BRA0500 Brucella suis 1330 monovalent cation/H+ antiporter subunit A NP_699687.1 479321 D 204722 CDS NP_699688.1 23500248 1164939 482239..482577 1 NC_004311.2 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 482577 1164939 BRA0501 Brucella suis 1330 monovalent cation/H+ antiporter subunit C NP_699688.1 482239 D 204722 CDS NP_699689.1 23500249 1164940 482580..484208 1 NC_004311.2 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 484208 1164940 BRA0502 Brucella suis 1330 monovalent cation/H+ antiporter subunit D NP_699689.1 482580 D 204722 CDS NP_699690.1 23500250 1164941 484205..484720 1 NC_004311.2 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit E 484720 1164941 BRA0503 Brucella suis 1330 monovalent cation/H+ antiporter subunit E NP_699690.1 484205 D 204722 CDS NP_699691.1 23500251 1164942 484717..484998 1 NC_004311.2 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit F 484998 phaF 1164942 phaF Brucella suis 1330 monovalent cation/H+ antiporter subunit F NP_699691.1 484717 D 204722 CDS NP_699692.1 23500252 1164943 484995..485357 1 NC_004311.2 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 485357 1164943 BRA0505 Brucella suis 1330 monovalent cation/H+ antiporter subunit G NP_699692.1 484995 D 204722 CDS NP_699693.1 23500253 1164944 485374..485706 1 NC_004311.2 hypothetical protein 485706 1164944 BRA0506 Brucella suis 1330 hypothetical protein NP_699693.1 485374 D 204722 CDS NP_699694.1 23500254 1164945 485782..486318 1 NC_004311.2 similar to GP:15159185, GB:Z27502, GB:Z29983, SP:P04438, PID:1335182, PID:32878, PID:474960, PID:505435, and PID:563647; identified by sequence similarity; hypothetical protein 486318 1164945 BRA0507 Brucella suis 1330 hypothetical protein NP_699694.1 485782 D 204722 CDS NP_699695.1 23500255 1164946 486426..488051 1 NC_004311.2 similar to GP:9858820, GB:M24400, SP:P17538, and PID:181190; identified by sequence similarity; ABC transporter ATP-binding protein CydD 488051 cydD 1164946 cydD Brucella suis 1330 ABC transporter ATP-binding protein CydD NP_699695.1 486426 D 204722 CDS NP_699696.1 23500256 1164947 488048..489730 1 NC_004311.2 similar to GP:9858821; identified by sequence similarity; ABC transporter ATP-binding/permease 489730 1164947 BRA0509 Brucella suis 1330 ABC transporter ATP-binding/permease NP_699696.1 488048 D 204722 CDS NP_699697.1 23500257 1164948 489874..491451 1 NC_004311.2 similar to GP:9858822, and SP:P11026; identified by sequence similarity; cytochrome d ubiquinol oxidase subunit I 491451 cydA 1164948 cydA Brucella suis 1330 cytochrome d ubiquinol oxidase subunit I NP_699697.1 489874 D 204722 CDS NP_699698.1 23500258 1164949 491457..492611 1 NC_004311.2 similar to GB:X59066, GB:X65460, GB:D28126, GB:D14710, SP:P25705, PID:28938, PID:34468, PID:559317, and PID:559325; identified by sequence similarity; cytochrome d ubiquinol oxidase subunit II 492611 cydB 1164949 cydB Brucella suis 1330 cytochrome d ubiquinol oxidase subunit II NP_699698.1 491457 D 204722 CDS NP_699699.1 23500259 1164950 492589..492783 1 NC_004311.2 similar to SP:P30858, GB:X86160, PID:769790, GB:U00096, PID:1651397, and PID:1787089; identified by sequence similarity; hypothetical protein 492783 ybgT 1164950 ybgT Brucella suis 1330 hypothetical protein NP_699699.1 492589 D 204722 CDS NP_699700.1 23500260 1164951 complement(492834..493607) 1 NC_004311.2 similar to GP:15073129; identified by sequence similarity; GntR family transcriptional regulator 493607 1164951 BRA0513 Brucella suis 1330 GntR family transcriptional regulator NP_699700.1 492834 R 204722 CDS NP_699701.1 23500261 1164952 complement(493604..494491) 1 NC_004311.2 similar to GP:15073128, and GP:15073128; identified by sequence similarity; hypothetical protein 494491 1164952 BRA0514 Brucella suis 1330 hypothetical protein NP_699701.1 493604 R 204722 CDS NP_699702.1 23500262 1164953 494655..494843 1 NC_004311.2 hypothetical protein 494843 1164953 BRA0515 Brucella suis 1330 hypothetical protein NP_699702.1 494655 D 204722 CDS NP_699703.1 23500263 1164954 494840..496099 1 NC_004311.2 similar to GP:15073126, and SP:Q00749; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 496099 1164954 BRA0516 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_699703.1 494840 D 204722 CDS NP_699704.1 23500264 1164955 complement(496324..496452) 1 NC_004311.2 hypothetical protein 496452 1164955 BRA0517 Brucella suis 1330 hypothetical protein NP_699704.1 496324 R 204722 CDS NP_699705.1 23500265 1164956 496472..497416 1 NC_004311.2 similar to GP:15073125, and SP:P29823; identified by sequence similarity; sugar ABC transporter permease 497416 1164956 BRA0518 Brucella suis 1330 sugar ABC transporter permease NP_699705.1 496472 D 204722 CDS NP_699706.1 23500266 1164957 497429..498268 1 NC_004311.2 similar to GP:15073124; identified by sequence similarity; sugar ABC transporter permease 498268 1164957 BRA0519 Brucella suis 1330 sugar ABC transporter permease NP_699706.1 497429 D 204722 CDS NP_699707.1 23500267 1164958 498265..499335 1 NC_004311.2 similar to GP:15073123; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 499335 1164958 BRA0520 Brucella suis 1330 Gfo/Idh/MocA family oxidoreductase NP_699707.1 498265 D 204722 CDS NP_699708.1 23500268 1164959 499365..500366 1 NC_004311.2 similar to GP:15073122, and SP:Q01937; identified by sequence similarity; sugar ABC transporter ATP-binding protein 500366 1164959 BRA0521 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_699708.1 499365 D 204722 CDS NP_699709.1 23500269 1164960 500419..500670 1 NC_004311.2 hypothetical protein 500670 1164960 BRA0522 Brucella suis 1330 hypothetical protein NP_699709.1 500419 D 204722 CDS NP_699710.1 23500270 1164961 500472..500639 1 NC_004311.2 hypothetical protein 500639 1164961 BRA0523 Brucella suis 1330 hypothetical protein NP_699710.1 500472 D 204722 CDS NP_699711.1 23500271 1164962 500967..502199 1 NC_004311.2 similar to GP:15075957, and SP:P09060; identified by sequence similarity; 2-oxoisovalerate dehydrogenase E1 component subunit alpha 502199 1164962 BRA0524 Brucella suis 1330 2-oxoisovalerate dehydrogenase E1 component subunit alpha NP_699711.1 500967 D 204722 CDS NP_699712.1 23500272 1164963 502303..503316 1 NC_004311.2 identified by match to PFAM protein family HMM PF02780; 2-oxoisovalerate dehydrogenase E1 503316 1164963 BRA0525 Brucella suis 1330 2-oxoisovalerate dehydrogenase E1 NP_699712.1 502303 D 204722 CDS NP_699713.1 23500273 1164964 503317..504612 1 NC_004311.2 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 504612 1164964 BRA0526 Brucella suis 1330 branched-chain alpha-keto acid dehydrogenase subunit E2 NP_699713.1 503317 D 204722 CDS NP_699714.1 23500274 1164965 504617..506011 1 NC_004311.2 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 506011 lpdA-3 1164965 lpdA-3 Brucella suis 1330 dihydrolipoamide dehydrogenase NP_699714.1 504617 D 204722 CDS NP_699715.1 23500275 1164966 complement(506000..506761) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02104; SurF1 family protein 506761 1164966 BRA0528 Brucella suis 1330 SurF1 family protein NP_699715.1 506000 R 204722 CDS NP_699716.1 23500276 1164967 507020..507274 1 NC_004311.2 hypothetical protein 507274 1164967 BRA0529 Brucella suis 1330 hypothetical protein NP_699716.1 507020 D 204722 CDS NP_699717.1 23500277 1164968 complement(507455..509920) 1 NC_004311.2 similar to GB:L07807, GB:L07810, GB:L07808, GB:L07809, SP:Q05193, PID:181849, and PID:181851; identified by sequence similarity; DNA translocase FtsK 509920 1164968 BRA0530 Brucella suis 1330 DNA translocase FtsK NP_699717.1 507455 R 204722 CDS NP_699718.1 23500278 1164969 complement(510215..511237) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03576; D-aminopeptidase 511237 1164969 BRA0531 Brucella suis 1330 D-aminopeptidase NP_699718.1 510215 R 204722 CDS NP_699719.1 23500279 1164970 511484..512794 1 NC_004311.2 similar to GP:15157414; identified by sequence similarity; major facilitator family transporter 512794 1164970 BRA0532 Brucella suis 1330 major facilitator family transporter NP_699719.1 511484 D 204722 CDS NP_699720.1 23500280 1164971 complement(512953..513591) 1 NC_004311.2 similar to GB:J05175, SP:P16442, PID:1783208, PID:1783212, PID:1783214, PID:1783218, PID:1783226, PID:2352626, PID:340078, and PID:992596; identified by sequence similarity; alkylated DNA repair protein AlkB 513591 alkB 1164971 alkB Brucella suis 1330 alkylated DNA repair protein AlkB NP_699720.1 512953 R 204722 CDS NP_699721.1 23500281 1164972 complement(513673..515283) 1 NC_004311.2 similar to GP:15158999; identified by sequence similarity; ABC transporter ATP-binding protein 515283 1164972 BRA0534 Brucella suis 1330 ABC transporter ATP-binding protein NP_699721.1 513673 R 204722 CDS NP_699722.1 23500282 1164973 complement(515285..516445) 1 NC_004311.2 similar to GP:15140749; identified by sequence similarity; oligopeptide ABC transporter permease 516445 1164973 BRA0535 Brucella suis 1330 oligopeptide ABC transporter permease NP_699722.1 515285 R 204722 CDS NP_699723.1 23500283 1164974 complement(516411..517334) 1 NC_004311.2 similar to GP:15158997, and SP:P24138; identified by sequence similarity; oligopeptide ABC transporter permease 517334 1164974 BRA0536 Brucella suis 1330 oligopeptide ABC transporter permease NP_699723.1 516411 R 204722 CDS NP_699724.1 23500284 1164975 complement(517549..519126) 1 NC_004311.2 similar to GP:13235555, and SP:P77348; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 519126 1164975 BRA0537 Brucella suis 1330 oligopeptide ABC transporter periplasmic oligopeptide-binding protein NP_699724.1 517549 R 204722 CDS NP_699725.1 23500285 1164976 complement(519237..520814) 1 NC_004311.2 similar to GP:15158996, and SP:P06202; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 520814 1164976 BRA0538 Brucella suis 1330 oligopeptide ABC transporter periplasmic oligopeptide-binding protein NP_699725.1 519237 R 204722 CDS NP_699726.1 23500286 1164977 complement(520908..521078) 1 NC_004311.2 hypothetical protein 521078 1164977 BRA0539 Brucella suis 1330 hypothetical protein NP_699726.1 520908 R 204722 CDS NP_699727.1 23500287 1164978 complement(521241..521588) 1 NC_004311.2 similar to GP:15074850; identified by sequence similarity; hypothetical protein 521588 1164978 BRA0540 Brucella suis 1330 hypothetical protein NP_699727.1 521241 R 204722 CDS NP_699728.1 23500288 1164979 complement(521842..522066) 1 NC_004311.2 hypothetical protein 522066 1164979 BRA0541 Brucella suis 1330 hypothetical protein NP_699728.1 521842 R 204722 CDS NP_699729.1 23500289 1164980 522383..523396 1 NC_004311.2 similar to GP:15140313; identified by sequence similarity; NAD-dependent epimerase/dehydratase 523396 1164980 BRA0542 Brucella suis 1330 NAD-dependent epimerase/dehydratase NP_699729.1 522383 D 204722 CDS NP_699730.1 23500290 1164981 523396..524382 1 NC_004311.2 similar to SP:P23157, GB:X55942, and PID:46921; identified by sequence similarity; UDP-glucose 4-epimerase 524382 galE-2 1164981 galE-2 Brucella suis 1330 UDP-glucose 4-epimerase NP_699730.1 523396 D 204722 CDS NP_699731.1 23500291 1164982 524379..526223 1 NC_004311.2 similar to GP:15140315; identified by sequence similarity; glycosyl transferase group 2 family protein 526223 1164982 BRA0544 Brucella suis 1330 glycosyl transferase group 2 family protein NP_699731.1 524379 D 204722 CDS NP_699732.1 23500292 1164983 526238..527662 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00745; UDP-glucose 6-dehydrogenase 527662 ugd 1164983 ugd Brucella suis 1330 UDP-glucose 6-dehydrogenase NP_699732.1 526238 D 204722 CDS NP_699733.1 23500293 1164984 527652..528197 1 NC_004311.2 similar to GP:15140316, and GP:15140316; identified by sequence similarity; hypothetical protein 528197 1164984 BRA0546 Brucella suis 1330 hypothetical protein NP_699733.1 527652 D 204722 CDS NP_699734.1 23500294 1164985 528247..529191 1 NC_004311.2 similar to GP:15140317; identified by sequence similarity; endoglucanase 529191 1164985 BRA0547 Brucella suis 1330 endoglucanase NP_699734.1 528247 D 204722 CDS NP_699735.1 23500295 1164986 529188..529805 1 NC_004311.2 similar to GP:15140318, and GP:15140318; identified by sequence similarity; hypothetical protein 529805 1164986 BRA0548 Brucella suis 1330 hypothetical protein NP_699735.1 529188 D 204722 CDS NP_699736.1 23500296 1164987 complement(529881..530207) 1 NC_004311.2 similar to GP:15160059; identified by sequence similarity; hypothetical protein 530207 1164987 BRA0549 Brucella suis 1330 hypothetical protein NP_699736.1 529881 R 204722 CDS NP_699737.1 23500297 1164988 complement(530350..531471) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 531471 1164988 BRA0550 Brucella suis 1330 AraC family transcriptional regulator NP_699737.1 530350 R 204722 CDS NP_699738.1 23500298 1164990 complement(532262..532573) 1 NC_004311.2 similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; IS711, transposase orfA 532573 1164990 BRA0552 Brucella suis 1330 IS711, transposase orfA NP_699738.1 532262 R 204722 CDS NP_699739.1 23500299 1164991 complement(532630..534594) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02566; cell wall surface protein 534594 1164991 BRA0553 Brucella suis 1330 cell wall surface protein NP_699739.1 532630 R 204722 CDS NP_699740.1 23500300 1164993 complement(535170..535775) 1 NC_004311.2 similar to SP:P14040, GB:X15970, and PID:44784; identified by sequence similarity; IS66 family orf4 535775 1164993 BRA0555 Brucella suis 1330 IS66 family orf4 NP_699740.1 535170 R 204722 CDS NP_699741.1 23500301 1164994 complement(535772..537343) 1 NC_004311.2 similar to GP:15140549, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; IS66 family orf3 537343 1164994 BRA0556 Brucella suis 1330 IS66 family orf3 NP_699741.1 535772 R 204722 CDS NP_699742.1 23500302 1164995 complement(537393..537779) 1 NC_004311.2 similar to GP:15076151, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; IS66 family orf2 537779 1164995 BRA0557 Brucella suis 1330 IS66 family orf2 NP_699742.1 537393 R 204722 CDS NP_699743.1 23500303 1164996 complement(537743..538210) 1 NC_004311.2 similar to GP:15076150, and GP:15076150; identified by sequence similarity; IS66 family Orf1 538210 1164996 BRA0558 Brucella suis 1330 IS66 family Orf1 NP_699743.1 537743 R 204722 CDS NP_699744.1 23500304 1164998 539354..539827 1 NC_004311.2 hypothetical protein 539827 1164998 BRA0560 Brucella suis 1330 hypothetical protein NP_699744.1 539354 D 204722 CDS NP_699745.1 23500305 1165000 540300..540758 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00011; hypothetical protein 540758 1165000 BRA0561 Brucella suis 1330 hypothetical protein NP_699745.1 540300 D 204722 CDS NP_699746.1 23500306 1165001 541004..541465 1 NC_004311.2 rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 541465 rirA 1165001 rirA Brucella suis 1330 iron-responsive transcriptional regulator NP_699746.1 541004 D 204722 CDS NP_699747.1 23500307 1165002 541582..541896 1 NC_004311.2 similar to GP:13277326, and GP:13277326; identified by sequence similarity; hypothetical protein 541896 1165002 BRA0563 Brucella suis 1330 hypothetical protein NP_699747.1 541582 D 204722 CDS NP_699748.1 23500308 1165003 542353..542664 1 NC_004311.2 similar to GP:15076196; identified by sequence similarity; hypothetical protein 542664 1165003 BRA0564 Brucella suis 1330 hypothetical protein NP_699748.1 542353 D 204722 CDS NP_699749.1 23500309 1165004 542630..543115 1 NC_004311.2 similar to SP:P22759; identified by sequence similarity; bacterioferritin 543115 bfr 1165004 bfr Brucella suis 1330 bacterioferritin NP_699749.1 542630 D 204722 CDS NP_699750.1 23500310 1165005 543279..544592 1 NC_004311.2 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 544592 rimO 1165005 rimO Brucella suis 1330 ribosomal protein S12 methylthiotransferase NP_699750.1 543279 D 204722 CDS NP_699751.1 23500311 1165006 complement(544732..545799) 1 NC_004311.2 similar to GP:15156897; identified by sequence similarity; bmp family protein 545799 1165006 BRA0567 Brucella suis 1330 bmp family protein NP_699751.1 544732 R 204722 CDS NP_699752.1 23500312 1165007 complement(545882..546802) 1 NC_004311.2 similar to GP:15156898; identified by sequence similarity; ABC transporter permease 546802 1165007 BRA0568 Brucella suis 1330 ABC transporter permease NP_699752.1 545882 R 204722 CDS NP_699753.1 23500313 1165008 complement(546807..547889) 1 NC_004311.2 similar to GP:13937515; identified by sequence similarity; ABC transporter permease 547889 1165008 BRA0569 Brucella suis 1330 ABC transporter permease NP_699753.1 546807 R 204722 CDS NP_699754.1 23500314 1165009 complement(547889..549451) 1 NC_004311.2 similar to GP:13937516; identified by sequence similarity; ABC transporter ATP-binding protein 549451 1165009 BRA0570 Brucella suis 1330 ABC transporter ATP-binding protein NP_699754.1 547889 R 204722 CDS NP_699755.1 23500315 1165010 complement(549555..550529) 1 NC_004311.2 similar to GP:15074605; identified by sequence similarity; quinone oxidoreductase 550529 qor 1165010 qor Brucella suis 1330 quinone oxidoreductase NP_699755.1 549555 R 204722 CDS NP_699756.1 23500316 1165011 complement(550526..551326) 1 NC_004311.2 similar to GP:6739568; identified by sequence similarity; phosphatidylcholine synthase 551326 pcs 1165011 pcs Brucella suis 1330 phosphatidylcholine synthase NP_699756.1 550526 R 204722 CDS NP_699757.1 23500317 1165012 551542..552900 1 NC_004311.2 similar to SP:P25534; identified by sequence similarity; 2-octaprenyl-6-methoxyphenyl hydroxylase 552900 ubiH 1165012 ubiH Brucella suis 1330 2-octaprenyl-6-methoxyphenyl hydroxylase NP_699757.1 551542 D 204722 CDS NP_699758.1 23500318 1165013 552973..553311 1 NC_004311.2 similar to GP:15074574; identified by sequence similarity; hypothetical protein 553311 1165013 BRA0574 Brucella suis 1330 hypothetical protein NP_699758.1 552973 D 204722 CDS NP_699759.1 23500319 1165014 complement(553444..554061) 1 NC_004311.2 similar to GP:14021474; identified by sequence similarity; hypothetical protein 554061 1165014 BRA0575 Brucella suis 1330 hypothetical protein NP_699759.1 553444 R 204722 CDS NP_699760.1 23500320 1165015 554406..556253 1 NC_004311.2 similar to GP:15074576; identified by sequence similarity; peptide ABC transporter substrate-binding protein 556253 1165015 BRA0576 Brucella suis 1330 peptide ABC transporter substrate-binding protein NP_699760.1 554406 D 204722 CDS NP_699761.1 23500321 1165016 556433..557107 1 NC_004311.2 identified by match to PFAM protein family HMM PF03046; frnE protein 557107 1165016 BRA0577 Brucella suis 1330 frnE protein NP_699761.1 556433 D 204722 CDS NP_699762.1 23500322 1165017 complement(557283..557681) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00903; fosfomycin resistance family protein 557681 1165017 BRA0578 Brucella suis 1330 fosfomycin resistance family protein NP_699762.1 557283 R 204722 CDS NP_699763.1 23500323 1165018 complement(557774..561142) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01587; transcription-repair coupling factor 561142 mfd 1165018 mfd Brucella suis 1330 transcription-repair coupling factor NP_699763.1 557774 R 204722 CDS NP_699764.1 23500324 1165019 complement(561297..561584) 1 NC_004311.2 similar to GP:15074586, and GP:15074586; identified by sequence similarity; hypothetical protein 561584 1165019 BRA0580 Brucella suis 1330 hypothetical protein NP_699764.1 561297 R 204722 CDS NP_699765.1 23500325 1165020 561723..563843 1 NC_004311.2 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 563843 recG 1165020 recG Brucella suis 1330 ATP-dependent DNA helicase RecG NP_699765.1 561723 D 204722 CDS NP_699766.1 23500326 1165021 complement(563998..565821) 1 NC_004311.2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 565821 glmS 1165021 glmS Brucella suis 1330 glucosamine--fructose-6-phosphate aminotransferase NP_699766.1 563998 R 204722 CDS NP_699767.1 23500327 1165022 complement(565925..567289) 1 NC_004311.2 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 567289 glmU 1165022 glmU Brucella suis 1330 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_699767.1 565925 R 204722 CDS NP_699768.1 23500328 1165023 complement(567371..568132) 1 NC_004311.2 similar to GP:6714962; identified by sequence similarity; cytochrome c-type biogenesis protein CcdA 568132 ccdA 1165023 ccdA Brucella suis 1330 cytochrome c-type biogenesis protein CcdA NP_699768.1 567371 R 204722 CDS NP_699769.1 23500329 1165024 568281..570923 1 NC_004311.2 similar to GP:15074112; identified by sequence similarity; hypothetical protein 570923 1165024 BRA0585 Brucella suis 1330 hypothetical protein NP_699769.1 568281 D 204722 CDS NP_699770.1 23500330 1165025 571172..572332 1 NC_004311.2 similar to GP:15157711, and GP:1196970; identified by sequence similarity; hypothetical protein 572332 1165025 BRA0586 Brucella suis 1330 hypothetical protein NP_699770.1 571172 D 204722 CDS NP_699771.1 23500331 1165027 complement(572836..573336) 1 NC_004311.2 similar to GP:3236220; identified by sequence similarity; hypothetical protein 573336 1165027 BRA0587 Brucella suis 1330 hypothetical protein NP_699771.1 572836 R 204722 CDS NP_699772.1 23500332 1165028 573654..575045 1 NC_004311.2 identified by match to PFAM protein family HMM PF00989; sensory box protein 575045 1165028 BRA0588 Brucella suis 1330 sensory box protein NP_699772.1 573654 D 204722 CDS NP_699773.1 23500333 1165029 575173..575976 1 NC_004311.2 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 575976 lipB 1165029 lipB Brucella suis 1330 lipoate-protein ligase B NP_699773.1 575173 D 204722 CDS NP_699774.1 23500334 1165030 complement(575980..576909) 1 NC_004311.2 similar to GP:15156645; identified by sequence similarity; hypothetical protein 576909 1165030 BRA0590 Brucella suis 1330 hypothetical protein NP_699774.1 575980 R 204722 CDS NP_699775.1 23500335 1165031 577214..579313 1 NC_004311.2 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 579313 parE 1165031 parE Brucella suis 1330 DNA topoisomerase IV subunit B NP_699775.1 577214 D 204722 CDS NP_699776.1 23500336 1165032 complement(579319..579501) 1 NC_004311.2 hypothetical protein 579501 1165032 BRA0592 Brucella suis 1330 hypothetical protein NP_699776.1 579319 R 204722 CDS NP_699777.1 23500337 1165033 complement(579486..579710) 1 NC_004311.2 hypothetical protein 579710 1165033 BRA0593 Brucella suis 1330 hypothetical protein NP_699777.1 579486 R 204722 CDS NP_699778.1 23500338 1165034 complement(579735..581216) 1 NC_004311.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 581216 gatA 1165034 gatA Brucella suis 1330 aspartyl/glutamyl-tRNA amidotransferase subunit A NP_699778.1 579735 R 204722 CDS NP_699779.1 23500339 1165035 complement(581275..581562) 1 NC_004311.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C 581562 gatC 1165035 gatC Brucella suis 1330 aspartyl/glutamyl-tRNA amidotransferase subunit C NP_699779.1 581275 R 204722 CDS NP_699780.1 23500340 1165036 complement(581657..582370) 1 NC_004311.2 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 582370 1165036 BRA0596 Brucella suis 1330 metal-dependent hydrolase NP_699780.1 581657 R 204722 CDS NP_699781.1 23500341 1165037 582470..582958 1 NC_004311.2 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 582958 1165037 BRA0597 Brucella suis 1330 Holliday junction resolvase-like protein NP_699781.1 582470 D 204722 CDS NP_699782.1 23500342 1165038 complement(582943..584598) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase 584598 1165038 BRA0598 Brucella suis 1330 acyl-CoA dehydrogenase NP_699782.1 582943 R 204722 CDS NP_699783.1 23500343 1165039 584755..585723 1 NC_004311.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 585723 pyrB 1165039 pyrB Brucella suis 1330 aspartate carbamoyltransferase NP_699783.1 584755 D 204722 CDS NP_699784.1 23500344 1165040 585720..587006 1 NC_004311.2 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 587006 pyrC-2 1165040 pyrC-2 Brucella suis 1330 dihydroorotase NP_699784.1 585720 D 204722 CDS NP_699785.1 23500345 1165041 587081..587686 1 NC_004311.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 587686 1165041 BRA0601 Brucella suis 1330 glycerol-3-phosphate acyltransferase PlsY NP_699785.1 587081 D 204722 CDS NP_699786.1 23500346 1165042 587683..588864 1 NC_004311.2 similar to GP:15156358; identified by sequence similarity; DNA processing protein DprA 588864 1165042 BRA0602 Brucella suis 1330 DNA processing protein DprA NP_699786.1 587683 D 204722 CDS NP_699787.1 23500347 1165043 complement(588874..589041) 1 NC_004311.2 hypothetical protein 589041 1165043 BRA0603 Brucella suis 1330 hypothetical protein NP_699787.1 588874 R 204722 CDS NP_699788.1 23500348 1165044 589297..591930 1 NC_004311.2 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 591930 topA 1165044 topA Brucella suis 1330 DNA topoisomerase I NP_699788.1 589297 D 204722 CDS NP_699789.1 23500349 1165045 591934..594285 1 NC_004311.2 similar to SP:P21499; identified by sequence similarity; VacB/RNase II family exoribonuclease 594285 1165045 BRA0605 Brucella suis 1330 VacB/RNase II family exoribonuclease NP_699789.1 591934 D 204722 CDS NP_699790.1 23500350 1165046 594285..594746 1 NC_004311.2 hypothetical protein 594746 1165046 BRA0606 Brucella suis 1330 hypothetical protein NP_699790.1 594285 D 204722 CDS NP_699791.1 23500351 1165047 594755..595486 1 NC_004311.2 similar to GP:6525218; identified by sequence similarity; MutT/nudix family protein 595486 1165047 BRA0607 Brucella suis 1330 MutT/nudix family protein NP_699791.1 594755 D 204722 CDS NP_699792.1 23500352 1165048 595561..596703 1 NC_004311.2 similar to GP:6525219; identified by sequence similarity; major facilitator family transporter 596703 1165048 BRA0608 Brucella suis 1330 major facilitator family transporter NP_699792.1 595561 D 204722 CDS NP_699793.1 23500353 1165049 596862..597029 1 NC_004311.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 597029 rpmG 1165049 rpmG Brucella suis 1330 50S ribosomal protein L33 NP_699793.1 596862 D 204722 CDS NP_699794.1 23500354 1165050 complement(597136..598521) 1 NC_004311.2 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 598521 pleD 1165050 pleD Brucella suis 1330 response regulator PleD NP_699794.1 597136 R 204722 CDS NP_699795.1 23500355 1165051 complement(598518..598649) 1 NC_004311.2 hypothetical protein 598649 1165051 BRA0611 Brucella suis 1330 hypothetical protein NP_699795.1 598518 R 204722 CDS NP_699796.1 23500356 1165052 complement(598642..599013) 1 NC_004311.2 similar to GP:6513589; identified by sequence similarity; polar differentiation response regulator 599013 divK 1165052 divK Brucella suis 1330 polar differentiation response regulator NP_699796.1 598642 R 204722 CDS NP_699797.1 23500357 1165053 599116..599481 1 NC_004311.2 similar to GP:15074224; identified by sequence similarity; hypothetical protein 599481 1165053 BRA0613 Brucella suis 1330 hypothetical protein NP_699797.1 599116 D 204722 CDS NP_699798.1 23500358 1165054 complement(599537..600046) 1 NC_004311.2 Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator 600046 1165054 BRA0614 Brucella suis 1330 nucleoside diphosphate kinase regulator NP_699798.1 599537 R 204722 CDS NP_699799.1 23500359 1165055 600497..601834 1 NC_004311.2 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 601834 1165055 BRA0615 Brucella suis 1330 DNA polymerase IV NP_699799.1 600497 D 204722 CDS NP_699800.1 23500360 1165056 602010..604199 1 NC_004311.2 similar to GP:15156313, and GP:15074191; identified by sequence similarity; hypothetical protein 604199 1165056 BRA0616 Brucella suis 1330 hypothetical protein NP_699800.1 602010 D 204722 CDS NP_699801.1 23500361 1165057 complement(604179..604301) 1 NC_004311.2 hypothetical protein 604301 1165057 BRA0617 Brucella suis 1330 hypothetical protein NP_699801.1 604179 R 204722 CDS NP_699802.1 23500362 1165059 complement(604728..605450) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein 605450 1165059 BRA0618 Brucella suis 1330 GGDEF domain-containing protein NP_699802.1 604728 R 204722 CDS NP_699803.1 23500363 1165060 complement(606123..606221) 1 NC_004311.2 hypothetical protein 606221 1165060 BRA0619 Brucella suis 1330 hypothetical protein NP_699803.1 606123 R 204722 CDS NP_699804.1 23500364 1165061 complement(606257..606370) 1 NC_004311.2 hypothetical protein 606370 1165061 BRA0620 Brucella suis 1330 hypothetical protein NP_699804.1 606257 R 204722 CDS NP_699805.1 23500365 1165062 complement(606348..606725) 1 NC_004311.2 similar to SP:P09795, and PID:154350; identified by sequence similarity; endonuclease V 606725 1165062 BRA0621 Brucella suis 1330 endonuclease V NP_699805.1 606348 R 204722 CDS NP_699806.1 23500366 1165063 606866..607171 1 NC_004311.2 hypothetical protein 607171 1165063 BRA0622 Brucella suis 1330 hypothetical protein NP_699806.1 606866 D 204722 CDS NP_699807.1 23500367 1165064 607316..607504 1 NC_004311.2 hypothetical protein 607504 1165064 BRA0623 Brucella suis 1330 hypothetical protein NP_699807.1 607316 D 204722 CDS NP_699809.1 23500369 1165066 607555..607848 1 NC_004311.2 hypothetical protein 607848 1165066 BRA0625 Brucella suis 1330 hypothetical protein NP_699809.1 607555 D 204722 CDS NP_699810.1 23500370 1165067 607942..608616 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01406; exonuclease 608616 1165067 BRA0626 Brucella suis 1330 exonuclease NP_699810.1 607942 D 204722 CDS NP_699811.1 23500371 1165069 608992..609273 1 NC_004311.2 similar to GP:15074546, and GP:15074546; identified by sequence similarity; hypothetical protein 609273 1165069 BRA0627 Brucella suis 1330 hypothetical protein NP_699811.1 608992 D 204722 CDS NP_699812.1 23500372 1165070 complement(609374..610333) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator 610333 1165070 BRA0628 Brucella suis 1330 AraC family transcriptional regulator NP_699812.1 609374 R 204722 CDS NP_699813.1 23500373 1165071 complement(610501..610662) 1 NC_004311.2 hypothetical protein 610662 1165071 BRA0629 Brucella suis 1330 hypothetical protein NP_699813.1 610501 R 204722 CDS NP_699814.1 23500374 1165072 complement(610688..611938) 1 NC_004311.2 similar to GP:15073672, and SP:Q98B75; identified by sequence similarity; amino acid dehydrogenase 611938 1165072 BRA0630 Brucella suis 1330 amino acid dehydrogenase NP_699814.1 610688 R 204722 CDS NP_699815.1 23500375 1165073 complement(612027..612788) 1 NC_004311.2 similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 612788 1165073 BRA0631 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_699815.1 612027 R 204722 CDS NP_699816.1 23500376 1165074 complement(612944..613717) 1 NC_004311.2 similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 613717 1165074 BRA0632 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_699816.1 612944 R 204722 CDS NP_699817.1 23500377 1165075 complement(613902..615005) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00899; hypothetical protein 615005 1165075 BRA0633 Brucella suis 1330 hypothetical protein NP_699817.1 613902 R 204722 CDS NP_699818.1 23500378 1165076 615107..615556 1 NC_004311.2 identified by match to PFAM protein family HMM PF01047; AsnC family transcriptional regulator 615556 1165076 BRA0634 Brucella suis 1330 AsnC family transcriptional regulator NP_699818.1 615107 D 204722 CDS NP_699819.1 23500379 1165077 615836..617563 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 617563 1165077 BRA0635 Brucella suis 1330 twin-arginine translocation pathway signal sequence domain-containing protein NP_699819.1 615836 D 204722 CDS NP_699820.1 23500380 1165078 complement(617674..618876) 1 NC_004311.2 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase 618876 pcaF 1165078 pcaF Brucella suis 1330 beta-ketoadipyl CoA thiolase NP_699820.1 617674 R 204722 CDS NP_699821.1 23500381 1165079 complement(618885..619574) 1 NC_004311.2 similar to GP:15158666, and SP:Q01104; identified by sequence similarity; 3-oxoadipate CoA-transferase subunit B 619574 pcaJ 1165079 pcaJ Brucella suis 1330 3-oxoadipate CoA-transferase subunit B NP_699821.1 618885 R 204722 CDS NP_699822.1 23500382 1165080 complement(619571..620278) 1 NC_004311.2 similar to GP:15158667, and SP:Q01103; identified by sequence similarity; 3-oxoadipate CoA-transferase subunit A 620278 pcaI 1165080 pcaI Brucella suis 1330 3-oxoadipate CoA-transferase subunit A NP_699822.1 619571 R 204722 CDS NP_699823.1 23500383 1165081 620462..621232 1 NC_004311.2 similar to GP:15141386; identified by sequence similarity; transcriptional regulator PcaR 621232 1165081 BRA0639 Brucella suis 1330 transcriptional regulator PcaR NP_699823.1 620462 D 204722 CDS NP_699824.1 23500384 1165082 complement(621239..622156) 1 NC_004311.2 similar to GP:6682325; identified by sequence similarity; pobR protein 622156 pobR 1165082 pobR Brucella suis 1330 pobR protein NP_699824.1 621239 R 204722 CDS NP_699825.1 23500385 1165083 622269..623438 1 NC_004311.2 catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 623438 pobA 1165083 pobA Brucella suis 1330 4-hydroxybenzoate 3-monooxygenase NP_699825.1 622269 D 204722 CDS NP_699826.1 23500386 1165084 complement(623848..624756) 1 NC_004311.2 similar to GP:15141380, GB:D21235, SP:P54725, PID:1905912, and PID:498146; identified by sequence similarity; transcriptional regulator PcaQ 624756 pcaQ 1165084 pcaQ Brucella suis 1330 transcriptional regulator PcaQ NP_699826.1 623848 R 204722 CDS NP_699827.1 23500387 1165085 624850..625653 1 NC_004311.2 similar to GP:15141379, and SP:P00632; identified by sequence similarity; 3-oxoadipate enol-lactone hydrolase 625653 pcaL 1165085 pcaL Brucella suis 1330 3-oxoadipate enol-lactone hydrolase NP_699827.1 624850 D 204722 CDS NP_699828.1 23500388 1165086 625657..626073 1 NC_004311.2 similar to GP:15141378; identified by sequence similarity; 4-carboxymuconolactone decarboxylase 626073 pcaC 1165086 pcaC Brucella suis 1330 4-carboxymuconolactone decarboxylase NP_699828.1 625657 D 204722 CDS NP_699829.1 23500389 1165087 626070..626810 1 NC_004311.2 similar to GP:11037223, and SP:P00437; identified by sequence similarity; protocatechuate 3,4-dioxygenase subunit beta 626810 pcaH 1165087 pcaH Brucella suis 1330 protocatechuate 3,4-dioxygenase subunit beta NP_699829.1 626070 D 204722 CDS NP_699830.1 23500390 1165088 626812..627429 1 NC_004311.2 similar to GP:11037224, GB:M12783, GB:X02811, GB:M19719, GB:X03702, GB:K01918, GB:X03493, GB:Y00389, GB:K01402, GB:X02745, GB:K01399, GB:X00560, GB:K01915, GB:K01917, GB:K01401, GB:X00562, GB:K01916, GB:K01400, GB:X00561, GB:K01913, GB:K01914, GB:J00121, GB:K01398, GB:X02744, GB:M32009, SP:P01127, PID:1335308, PID:1335309, PID:1335310, PID:1335311, PID:1621242, PID:1888419, PID:2294400, PID:2294421, PID:2294425, PID:2297379, PID:30247, PID:338199, PID:338209, PID:338211, PID:35372, PID:35375, PID:35377, PID:36481, and PID:951025; identified by sequence similarity; protocatechuate 3,4-dioxygenase subunit alpha 627429 pcaG 1165088 pcaG Brucella suis 1330 protocatechuate 3,4-dioxygenase subunit alpha NP_699830.1 626812 D 204722 CDS NP_699831.1 23500391 1165089 627433..628497 1 NC_004311.2 Catalyzes the cycloisomerization of cis,cis-muconate; 3-carboxy-cis,cis-muconate cycloisomerase 628497 1165089 BRA0647 Brucella suis 1330 3-carboxy-cis,cis-muconate cycloisomerase NP_699831.1 627433 D 204722 CDS NP_699832.1 23500392 1165090 628633..629805 1 NC_004311.2 similar to GP:15158698; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 629805 1165090 BRA0648 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_699832.1 628633 D 204722 CDS NP_699833.1 23500393 1165091 629978..630847 1 NC_004311.2 similar to GP:15158699; identified by sequence similarity; branched-chain amino acid ABC transporter permease 630847 1165091 BRA0649 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699833.1 629978 D 204722 CDS NP_699834.1 23500394 1165092 630844..631830 1 NC_004311.2 similar to GP:15158700; identified by sequence similarity; branched-chain amino acid ABC transporter permease 631830 1165092 BRA0650 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_699834.1 630844 D 204722 CDS NP_699835.1 23500395 1165093 631827..632576 1 NC_004311.2 similar to GP:15158701; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 632576 1165093 BRA0651 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_699835.1 631827 D 204722 CDS NP_699836.1 23500396 1165094 632573..633289 1 NC_004311.2 similar to GP:15158702; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 633289 1165094 BRA0652 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_699836.1 632573 D 204722 CDS NP_699837.1 23500397 1165095 complement(633290..635035) 1 NC_004311.2 similar to GB:Y00636, GB:X06296, SP:P19256, PID:34347, PID:34350, and PID:540515; identified by sequence similarity; adenine deaminase 635035 ade 1165095 ade Brucella suis 1330 adenine deaminase NP_699837.1 633290 R 204722 CDS NP_699838.1 23500398 1165096 635194..636234 1 NC_004311.2 similar to GP:15157708; identified by sequence similarity; renal dipeptidase 636234 1165096 BRA0654 Brucella suis 1330 renal dipeptidase NP_699838.1 635194 D 204722 CDS NP_699839.1 23500399 1165097 636567..637868 1 NC_004311.2 similar to GP:15140275, and GP:43244; identified by sequence similarity; glycerol-3-phosphate ABC transporter periplasmic glycerol-3-phosphate-binding protein 637868 ugpB 1165097 ugpB Brucella suis 1330 glycerol-3-phosphate ABC transporter periplasmic glycerol-3-phosphate-binding protein NP_699839.1 636567 D 204722 CDS NP_699840.1 23500400 1165098 637941..638822 1 NC_004311.2 similar to GP:15140276; identified by sequence similarity; glycerol-3-phosphate ABC transporter permease 638822 ugpA 1165098 ugpA Brucella suis 1330 glycerol-3-phosphate ABC transporter permease NP_699840.1 637941 D 204722 CDS NP_699841.1 23500401 1165099 638834..639682 1 NC_004311.2 similar to GP:15160208; identified by sequence similarity; glycerol-3-phosphate ABC transporter permease 639682 ugpE 1165099 ugpE Brucella suis 1330 glycerol-3-phosphate ABC transporter permease NP_699841.1 638834 D 204722 CDS NP_699842.1 23500402 1165100 639682..640737 1 NC_004311.2 part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 640737 ugpC 1165100 ugpC Brucella suis 1330 glycerol-3-phosphate transporter ATP-binding subunit NP_699842.1 639682 D 204722 CDS NP_699843.1 23500403 1165101 640911..642770 1 NC_004311.2 similar to GP:15075030; identified by sequence similarity; TrkA family protein 642770 1165101 BRA0659 Brucella suis 1330 TrkA family protein NP_699843.1 640911 D 204722 CDS NP_699844.1 23500404 1165102 complement(642848..643447) 1 NC_004311.2 similar to GP:15074401; identified by sequence similarity; cytidine/deoxycytidylate deaminase 643447 1165102 BRA0660 Brucella suis 1330 cytidine/deoxycytidylate deaminase NP_699844.1 642848 R 204722 CDS NP_699845.1 23500405 1165103 complement(643508..644800) 1 NC_004311.2 similar to GP:15140670; identified by sequence similarity; uracil-xanthine permease 644800 1165103 BRA0661 Brucella suis 1330 uracil-xanthine permease NP_699845.1 643508 R 204722 CDS NP_699846.1 23500406 1165104 complement(645069..645233) 1 NC_004311.2 hypothetical protein 645233 1165104 BRA0662 Brucella suis 1330 hypothetical protein NP_699846.1 645069 R 204722 CDS NP_699847.1 23500407 1165106 645926..646108 1 NC_004311.2 hypothetical protein 646108 1165106 BRA0664 Brucella suis 1330 hypothetical protein NP_699847.1 645926 D 204722 CDS NP_699848.1 23500408 1165107 complement(646112..646249) 1 NC_004311.2 similar to GP:15073153; identified by sequence similarity; hypothetical protein 646249 1165107 BRA0665 Brucella suis 1330 hypothetical protein NP_699848.1 646112 R 204722 CDS NP_699849.1 23500409 1165108 646508..647425 1 NC_004311.2 similar to GP:15156879; identified by sequence similarity; hypothetical protein 647425 1165108 BRA0666 Brucella suis 1330 hypothetical protein NP_699849.1 646508 D 204722 CDS NP_699850.1 23500410 1165110 648385..648576 1 NC_004311.2 hypothetical protein 648576 1165110 BRA0668 Brucella suis 1330 hypothetical protein NP_699850.1 648385 D 204722 CDS NP_699851.1 23500411 1165111 648573..649334 1 NC_004311.2 identified by match to PFAM protein family HMM PF03647; hypothetical protein 649334 1165111 BRA0669 Brucella suis 1330 hypothetical protein NP_699851.1 648573 D 204722 CDS NP_699852.1 23500412 1165112 649406..651061 1 NC_004311.2 proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 651061 1165112 BRA0670 Brucella suis 1330 FAD-binding dehydrogenase NP_699852.1 649406 D 204722 CDS NP_699853.1 23500413 1165113 651070..651594 1 NC_004311.2 hypothetical protein 651594 1165113 BRA0671 Brucella suis 1330 hypothetical protein NP_699853.1 651070 D 204722 CDS NP_699855.1 23500415 1165115 651808..653166 1 NC_004311.2 similar to GP:15075528; identified by sequence similarity; aldehyde dehydrogenase 653166 1165115 BRA0673 Brucella suis 1330 aldehyde dehydrogenase NP_699855.1 651808 D 204722 CDS NP_699856.1 23500416 1165116 653475..653585 1 NC_004311.2 hypothetical protein 653585 1165116 BRA0674 Brucella suis 1330 hypothetical protein NP_699856.1 653475 D 204722 CDS NP_699857.1 23500417 1165117 653644..654591 1 NC_004311.2 similar to GP:15157658, and SP:P15028; identified by sequence similarity; iron ABC transporter substrate-binding protein 654591 1165117 BRA0675 Brucella suis 1330 iron ABC transporter substrate-binding protein NP_699857.1 653644 D 204722 CDS NP_699858.1 23500418 1165118 654648..655610 1 NC_004311.2 similar to GP:15157659, and SP:P37738; identified by sequence similarity; iron ABC transporter permease 655610 1165118 BRA0676 Brucella suis 1330 iron ABC transporter permease NP_699858.1 654648 D 204722 CDS NP_699859.1 23500419 1165119 655603..656556 1 NC_004311.2 similar to GP:15157660, and SP:P37737; identified by sequence similarity; iron ABC transporter permease 656556 1165119 BRA0677 Brucella suis 1330 iron ABC transporter permease NP_699859.1 655603 D 204722 CDS NP_699860.1 23500420 1165120 656553..657311 1 NC_004311.2 similar to GP:15157661, and GP:15023678; identified by sequence similarity; iron ABC transporter ATP-binding protein 657311 1165120 BRA0678 Brucella suis 1330 iron ABC transporter ATP-binding protein NP_699860.1 656553 D 204722 CDS NP_699861.1 23500421 1165121 complement(657364..657963) 1 NC_004311.2 similar to GP:14023727; identified by sequence similarity; hypothetical protein 657963 1165121 BRA0679 Brucella suis 1330 hypothetical protein NP_699861.1 657364 R 204722 CDS NP_699862.1 23500422 1165122 657994..658089 1 NC_004311.2 hypothetical protein 658089 1165122 BRA0680 Brucella suis 1330 hypothetical protein NP_699862.1 657994 D 204722 CDS NP_699863.1 23500423 1165123 658101..661697 1 NC_004311.2 similar to GP:15139898; identified by sequence similarity; hydantoinase/oxoprolinase 661697 1165123 BRA0681 Brucella suis 1330 hydantoinase/oxoprolinase NP_699863.1 658101 D 204722 CDS NP_699864.1 23500424 1165124 661983..662756 1 NC_004311.2 similar to GP:15076300; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 662756 fliY 1165124 fliY Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_699864.1 661983 D 204722 CDS NP_699865.1 23500425 1165125 662936..663616 1 NC_004311.2 similar to GP:15076302; identified by sequence similarity; amino acid ABC transporter permease 663616 1165125 BRA0683 Brucella suis 1330 amino acid ABC transporter permease NP_699865.1 662936 D 204722 CDS NP_699866.1 23500426 1165126 663613..664374 1 NC_004311.2 similar to GP:15076303, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, and PID:458555; identified by sequence similarity; amino acid ABC transporter ATP-binding protein 664374 1165126 BRA0684 Brucella suis 1330 amino acid ABC transporter ATP-binding protein NP_699866.1 663613 D 204722 CDS NP_699867.1 23500427 1165127 664616..666112 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01622; Ppx/GppA phosphatase 666112 1165127 BRA0685 Brucella suis 1330 Ppx/GppA phosphatase NP_699867.1 664616 D 204722 CDS NP_699868.1 23500428 1165128 666189..666836 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00438; ribosomal RNA large subunit methyltransferase J 666836 1165128 BRA0686 Brucella suis 1330 ribosomal RNA large subunit methyltransferase J NP_699868.1 666189 D 204722 CDS NP_699869.1 23500429 1165129 complement(667035..668444) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00897; Bcr/CflA subfamily drug resistance transporter 668444 1165129 BRA0687 Brucella suis 1330 Bcr/CflA subfamily drug resistance transporter NP_699869.1 667035 R 204722 CDS NP_699870.1 23500430 1165130 complement(668488..668772) 1 NC_004311.2 hypothetical protein 668772 1165130 BRA0688 Brucella suis 1330 hypothetical protein NP_699870.1 668488 R 204722 CDS NP_699871.1 23500431 1165131 668784..668885 1 NC_004311.2 hypothetical protein 668885 1165131 BRA0689 Brucella suis 1330 hypothetical protein NP_699871.1 668784 D 204722 CDS NP_699872.1 23500432 1165133 complement(670139..671020) 1 NC_004311.2 similar to GP:15076325; identified by sequence similarity; sugar ABC transporter permease 671020 1165133 BRA0691 Brucella suis 1330 sugar ABC transporter permease NP_699872.1 670139 R 204722 CDS NP_699873.1 23500433 1165134 complement(671017..672066) 1 NC_004311.2 similar to GP:13936895, and GP:2828821; identified by sequence similarity; sugar ABC transporter permease 672066 1165134 BRA0692 Brucella suis 1330 sugar ABC transporter permease NP_699873.1 671017 R 204722 CDS NP_699874.1 23500434 1165135 complement(672174..673439) 1 NC_004311.2 similar to GP:9964068, GB:L19113, SP:P39143, PID:437318, and GB:AL009126; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 673439 1165135 BRA0693 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_699874.1 672174 R 204722 CDS NP_699875.1 23500435 1165136 complement(673934..674182) 1 NC_004311.2 hypothetical protein 674182 1165136 BRA0694 Brucella suis 1330 hypothetical protein NP_699875.1 673934 R 204722 CDS NP_699876.1 23500436 1165137 674326..674802 1 NC_004311.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; riboflavin synthase subunit beta 674802 ribH 1165137 ribH Brucella suis 1330 riboflavin synthase subunit beta NP_699876.1 674326 D 204722 CDS NP_699877.1 23500437 1165139 675721..676065 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01244; hypothetical protein 676065 1165139 BRA0697 Brucella suis 1330 hypothetical protein NP_699877.1 675721 D 204722 CDS NP_699878.1 23500438 1165140 complement(676032..676268) 1 NC_004311.2 hypothetical protein 676268 1165140 BRA0698 Brucella suis 1330 hypothetical protein NP_699878.1 676032 R 204722 CDS NP_699879.1 23500439 1165141 complement(676714..678483) 1 NC_004311.2 similar to GP:15155325, and SP:P71338; identified by sequence similarity; iron ABC transporter permease 678483 1165141 BRA0699 Brucella suis 1330 iron ABC transporter permease NP_699879.1 676714 R 204722 CDS NP_699880.1 23500440 1165142 complement(678504..679520) 1 NC_004311.2 similar to GP:15155324, and SP:P35755; identified by sequence similarity; iron ABC transporter substrate-binding protein 679520 1165142 BRA0700 Brucella suis 1330 iron ABC transporter substrate-binding protein NP_699880.1 678504 R 204722 CDS NP_699881.1 23500441 1165143 complement(679646..680749) 1 NC_004311.2 similar to GP:15155323; identified by sequence similarity; iron ABC transporter ATP-binding protein 680749 1165143 BRA0701 Brucella suis 1330 iron ABC transporter ATP-binding protein NP_699881.1 679646 R 204722 CDS NP_699882.1 23500442 1165144 680986..682314 1 NC_004311.2 similar to GP:15075956; identified by sequence similarity; D-amino acid oxidase 682314 1165144 BRA0702 Brucella suis 1330 D-amino acid oxidase NP_699882.1 680986 D 204722 CDS NP_699883.1 23500443 1165145 complement(682572..683093) 1 NC_004311.2 similar to GB:M92844, GB:M63625, GB:M92843, SP:P26651, PID:183443, PID:183445, PID:340013, SP:P20922, and PID:581487; identified by sequence similarity; superoxide dismutase, Cu-Zn 683093 sodC 1165145 sodC Brucella suis 1330 superoxide dismutase, Cu-Zn NP_699883.1 682572 R 204722 CDS NP_699884.1 23500444 1165146 complement(683369..684973) 1 NC_004311.2 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase 684973 1165146 BRA0704 Brucella suis 1330 multicopper oxidase NP_699884.1 683369 R 204722 CDS NP_699885.1 23500445 1165147 complement(685033..685428) 1 NC_004311.2 hypothetical protein 685428 1165147 BRA0705 Brucella suis 1330 hypothetical protein NP_699885.1 685033 R 204722 CDS NP_699886.1 23500446 1165148 685682..686962 1 NC_004311.2 similar to GP:15075195; identified by sequence similarity; major facilitator family transporter 686962 1165148 BRA0706 Brucella suis 1330 major facilitator family transporter NP_699886.1 685682 D 204722 CDS NP_699887.1 23500447 1165149 complement(687040..687567) 1 NC_004311.2 similar to GP:12620484; identified by sequence similarity; alkyl hydroperoxide reductase 687567 ahpD 1165149 ahpD Brucella suis 1330 alkyl hydroperoxide reductase NP_699887.1 687040 R 204722 CDS NP_699888.1 23500448 1165150 complement(687647..688201) 1 NC_004311.2 similar to GP:12620485, and GP:12620485; identified by sequence similarity; alkyl hydroperoxide reductase 688201 ahpC 1165150 ahpC Brucella suis 1330 alkyl hydroperoxide reductase NP_699888.1 687647 R 204722 CDS NP_699889.1 23500449 1165151 688327..689232 1 NC_004311.2 similar to GB:L04510, SP:P36406, and PID:292070; identified by sequence similarity; transcriptional regulator OxyR 689232 1165151 BRA0709 Brucella suis 1330 transcriptional regulator OxyR NP_699889.1 688327 D 204722 CDS NP_699890.1 23500450 1165152 complement(689262..690329) 1 NC_004311.2 similar to GP:15159268, SP:P07002, GB:X66086, PID:42457, GB:U00096, PID:1742636, PID:1742642, PID:1742653, and PID:1787886; identified by sequence similarity; hypothetical protein 690329 1165152 BRA0710 Brucella suis 1330 hypothetical protein NP_699890.1 689262 R 204722 CDS NP_699891.1 23500451 1165153 complement(690427..691419) 1 NC_004311.2 similar to GP:15159273, and SP:O68965; identified by sequence similarity; myo-inositol 2-dehydrogenase 691419 idhA 1165153 idhA Brucella suis 1330 myo-inositol 2-dehydrogenase NP_699891.1 690427 R 204722 CDS NP_699892.1 23500452 1165154 691653..692423 1 NC_004311.2 similar to GP:15158705; identified by sequence similarity; SIS domain-containing protein 692423 1165154 BRA0712 Brucella suis 1330 SIS domain-containing protein NP_699892.1 691653 D 204722 CDS NP_699893.1 23500453 1165156 694451..696274 1 NC_004311.2 similar to GP:15158707, and GP:7209271; identified by sequence similarity; TPP-requiring enzyme IolD 696274 iolD 1165156 iolD Brucella suis 1330 TPP-requiring enzyme IolD NP_699893.1 694451 D 204722 CDS NP_699894.1 23500454 1165157 696278..697180 1 NC_004311.2 similar to GP:15158708; identified by sequence similarity; hypothetical protein 697180 iolE 1165157 iolE Brucella suis 1330 hypothetical protein NP_699894.1 696278 D 204722 CDS NP_699895.1 23500455 1165159 complement(698026..698826) 1 NC_004311.2 similar to GP:15140221, GB:X56692, GB:M11725, GB:M11880, GB:M35163, SP:P02741, PID:181066, PID:181068, PID:181073, and PID:30213; identified by sequence similarity; inositol monophosphatase 698826 1165159 BRA0717 Brucella suis 1330 inositol monophosphatase NP_699895.1 698026 R 204722 CDS NP_699896.1 23500456 1165160 complement(698847..699908) 1 NC_004311.2 similar to GP:15140222; identified by sequence similarity; ABC transporter ATP-binding protein 699908 1165160 BRA0718 Brucella suis 1330 ABC transporter ATP-binding protein NP_699896.1 698847 R 204722 CDS NP_699897.1 23500457 1165161 complement(699905..702130) 1 NC_004311.2 similar to GP:15158391, and GP:17743296; identified by sequence similarity; ABC transporter permease 702130 1165161 BRA0719 Brucella suis 1330 ABC transporter permease NP_699897.1 699905 R 204722 CDS NP_699898.1 23500458 1165162 complement(702265..703290) 1 NC_004311.2 similar to GP:15140224; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein 703290 1165162 BRA0720 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_699898.1 702265 R 204722 CDS NP_699899.1 23500459 1165163 703274..703417 1 NC_004311.2 hypothetical protein 703417 1165163 BRA0721 Brucella suis 1330 hypothetical protein NP_699899.1 703274 D 204722 CDS YP_002519392.1 221090244 1165164 complement(703520..707203) 1 NC_004311.2 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 707203 putA 1165164 putA Brucella suis 1330 bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_002519392.1 703520 R 204722 CDS NP_699900.1 23500460 1165165 707366..707860 1 NC_004311.2 similar to GB:M64551, SP:P26514, PID:153527, GB:M64551, SP:P26514, and PID:153527; identified by sequence similarity; proline dehydrogenase 707860 1165165 BRA0723 Brucella suis 1330 proline dehydrogenase NP_699900.1 707366 D 204722 CDS NP_699901.1 23500461 1165166 complement(707842..707955) 1 NC_004311.2 hypothetical protein 707955 1165166 BRA0724 Brucella suis 1330 hypothetical protein NP_699901.1 707842 R 204722 CDS NP_699902.1 23500462 1165167 complement(708891..711689) 1 NC_004311.2 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase 711689 gcvP 1165167 gcvP Brucella suis 1330 glycine dehydrogenase NP_699902.1 708891 R 204722 CDS NP_699903.1 23500463 1165168 complement(711694..712062) 1 NC_004311.2 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H 712062 gcvH 1165168 gcvH Brucella suis 1330 glycine cleavage system protein H NP_699903.1 711694 R 204722 CDS NP_699904.1 23500464 1165169 complement(712068..713171) 1 NC_004311.2 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T 713171 gcvT 1165169 gcvT Brucella suis 1330 glycine cleavage system aminomethyltransferase T NP_699904.1 712068 R 204722 CDS NP_699905.1 23500465 1165170 713813..713971 1 NC_004311.2 similar to GP:15074478; identified by sequence similarity; hypothetical protein 713971 1165170 BRA0728 Brucella suis 1330 hypothetical protein NP_699905.1 713813 D 204722 CDS NP_699906.1 23500466 1165171 complement(714153..715382) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01424; pyridine nucleotide-disulfide oxidoreductase 715382 1165171 BRA0729 Brucella suis 1330 pyridine nucleotide-disulfide oxidoreductase NP_699906.1 714153 R 204722 CDS NP_699907.1 23500467 1165172 complement(715494..716438) 1 NC_004311.2 similar to GP:15024826; identified by sequence similarity; transcriptional regulator 716438 1165172 BRA0730 Brucella suis 1330 transcriptional regulator NP_699907.1 715494 R 204722 CDS NP_699908.1 23500468 1165173 716465..717262 1 NC_004311.2 hypothetical protein 717262 1165173 BRA0731 Brucella suis 1330 hypothetical protein NP_699908.1 716465 D 204722 CDS NP_699909.1 23500469 1165174 717326..718693 1 NC_004311.2 identified by match to PFAM protein family HMM PF00120; glutamine synthetase 718693 1165174 BRA0732 Brucella suis 1330 glutamine synthetase NP_699909.1 717326 D 204722 CDS NP_699910.1 23500470 1165175 complement(718687..718803) 1 NC_004311.2 hypothetical protein 718803 1165175 BRA0733 Brucella suis 1330 hypothetical protein NP_699910.1 718687 R 204722 CDS NP_699911.1 23500471 1165176 718794..719963 1 NC_004311.2 similar to GB:M33308, SP:P18206, PID:292902, and PID:340237; identified by sequence similarity; alcohol dehydrogenase 719963 1165176 BRA0734 Brucella suis 1330 alcohol dehydrogenase NP_699911.1 718794 D 204722 CDS NP_699912.1 23500472 1165177 720145..720588 1 NC_004311.2 similar to GP:3236220, and GP:3236220; identified by sequence similarity; hypothetical protein 720588 1165177 BRA0735 Brucella suis 1330 hypothetical protein NP_699912.1 720145 D 204722 CDS NP_699913.1 23500473 1165178 720718..720915 1 NC_004311.2 hypothetical protein 720915 1165178 BRA0736 Brucella suis 1330 hypothetical protein NP_699913.1 720718 D 204722 CDS NP_699914.1 23500474 1165179 721051..721896 1 NC_004311.2 similar to GP:15075527; identified by sequence similarity; hypothetical protein 721896 1165179 BRA0737 Brucella suis 1330 hypothetical protein NP_699914.1 721051 D 204722 CDS NP_699915.1 23500475 1165180 complement(721942..722808) 1 NC_004311.2 similar to GP:19747452; identified by sequence similarity; glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein 722808 1165180 BRA0738 Brucella suis 1330 glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein NP_699915.1 721942 R 204722 CDS NP_699916.1 23500476 1165181 complement(722862..723767) 1 NC_004311.2 similar to GP:6119662, and GP:6119854; identified by sequence similarity; glycine betaine/L-proline ABC transporter permease 723767 1165181 BRA0739 Brucella suis 1330 glycine betaine/L-proline ABC transporter permease NP_699916.1 722862 R 204722 CDS NP_699917.1 23500477 1165182 complement(723830..724996) 1 NC_004311.2 similar to SP:P46920, GB:M88282, SP:P40200, and PID:338672; identified by sequence similarity; glycine betaine/L-proline ABC transporter ATP-binding protein 724996 1165182 BRA0740 Brucella suis 1330 glycine betaine/L-proline ABC transporter ATP-binding protein NP_699917.1 723830 R 204722 CDS NP_699918.1 23500478 1165183 complement(725209..725394) 1 NC_004311.2 hypothetical protein 725394 1165183 BRA0741 Brucella suis 1330 hypothetical protein NP_699918.1 725209 R 204722 CDS NP_699919.1 23500479 1165184 complement(725557..726030) 1 NC_004311.2 hypothetical protein 726030 1165184 BRA0742 Brucella suis 1330 hypothetical protein NP_699919.1 725557 R 204722 CDS NP_699920.1 23500480 1165185 complement(726044..727111) 1 NC_004311.2 similar to GP:15140598; identified by sequence similarity; amino acid processing-like protein 727111 1165185 BRA0743 Brucella suis 1330 amino acid processing-like protein NP_699920.1 726044 R 204722 CDS NP_699921.1 23500481 1165186 complement(727116..728033) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00441; RpiR family transcriptional regulator 728033 1165186 BRA0744 Brucella suis 1330 RpiR family transcriptional regulator NP_699921.1 727116 R 204722 CDS NP_699922.1 23500482 1165187 complement(728005..729057) 1 NC_004311.2 similar to SP:P55604; identified by sequence similarity; sugar ABC transporter ATP-binding protein 729057 1165187 BRA0745 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_699922.1 728005 R 204722 CDS NP_699923.1 23500483 1165188 complement(729062..729835) 1 NC_004311.2 similar to GP:14024269; identified by sequence similarity; short chain dehydrogenase/reductase oxidoreductase 729835 1165188 BRA0746 Brucella suis 1330 short chain dehydrogenase/reductase oxidoreductase NP_699923.1 729062 R 204722 CDS NP_699924.1 23500484 1165189 729852..729962 1 NC_004311.2 hypothetical protein 729962 1165189 BRA0747 Brucella suis 1330 hypothetical protein NP_699924.1 729852 D 204722 CDS NP_699925.1 23500485 1165190 730015..731250 1 NC_004311.2 similar to GP:2828820; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 731250 1165190 BRA0748 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_699925.1 730015 D 204722 CDS NP_699926.1 23500486 1165191 731323..732192 1 NC_004311.2 similar to GP:2828821; identified by sequence similarity; sugar ABC transporter permease 732192 1165191 BRA0749 Brucella suis 1330 sugar ABC transporter permease NP_699926.1 731323 D 204722 CDS NP_699927.1 23500487 1165192 732189..733016 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter permease 733016 1165192 BRA0750 Brucella suis 1330 sugar ABC transporter permease NP_699927.1 732189 D 204722 CDS NP_699928.1 23500488 1165193 733029..733400 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00004; endoribonuclease L-PSP 733400 1165193 BRA0751 Brucella suis 1330 endoribonuclease L-PSP NP_699928.1 733029 D 204722 CDS NP_699929.1 23500489 1165194 733427..734896 1 NC_004311.2 hypothetical protein 734896 1165194 BRA0752 Brucella suis 1330 hypothetical protein NP_699929.1 733427 D 204722 CDS NP_699930.1 23500490 1165195 complement(735057..735299) 1 NC_004311.2 hypothetical protein 735299 1165195 BRA0753 Brucella suis 1330 hypothetical protein NP_699930.1 735057 R 204722 CDS NP_699931.1 23500491 1165196 complement(735357..736154) 1 NC_004311.2 similar to GP:15139930, and GP:8217385; identified by sequence similarity; iron ABC transporter ATP-binding protein 736154 1165196 BRA0754 Brucella suis 1330 iron ABC transporter ATP-binding protein NP_699931.1 735357 R 204722 CDS NP_699932.1 23500492 1165197 complement(736151..737194) 1 NC_004311.2 similar to GP:15139929; identified by sequence similarity; iron ABC transporter permease 737194 1165197 BRA0755 Brucella suis 1330 iron ABC transporter permease NP_699932.1 736151 R 204722 CDS NP_699933.1 23500493 1165198 complement(737191..738225) 1 NC_004311.2 similar to GP:15159961, and GP:8546929; identified by sequence similarity; iron ABC transporter substrate-binding protein 738225 1165198 BRA0756 Brucella suis 1330 iron ABC transporter substrate-binding protein NP_699933.1 737191 R 204722 CDS NP_699934.1 23500494 1165199 complement(738182..738598) 1 NC_004311.2 hypothetical protein 738598 1165199 BRA0757 Brucella suis 1330 hypothetical protein NP_699934.1 738182 R 204722 CDS NP_699935.1 23500495 1165200 complement(738776..739642) 1 NC_004311.2 similar to GP:15162366; identified by sequence similarity; HlyD family secretion protein 739642 1165200 BRA0758 Brucella suis 1330 HlyD family secretion protein NP_699935.1 738776 R 204722 CDS NP_699936.1 23500496 1165201 complement(739639..739848) 1 NC_004311.2 similar to GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, PID:567108, GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, and PID:567108; identified by sequence similarity; hypothetical protein 739848 1165201 BRA0759 Brucella suis 1330 hypothetical protein NP_699936.1 739639 R 204722 CDS NP_699937.1 23500497 1165202 complement(739875..741971) 1 NC_004311.2 similar to GP:15162367; identified by sequence similarity; hypothetical protein 741971 1165202 BRA0760 Brucella suis 1330 hypothetical protein NP_699937.1 739875 R 204722 CDS NP_699938.1 23500498 1165203 complement(742014..742451) 1 NC_004311.2 similar to GP:15074064; identified by sequence similarity; MarR family transcriptional regulator 742451 1165203 BRA0761 Brucella suis 1330 MarR family transcriptional regulator NP_699938.1 742014 R 204722 CDS NP_699939.2 229107039 1165204 742701..743447 1 NC_004311.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 743447 1165204 BRA0762 Brucella suis 1330 16S ribosomal RNA methyltransferase RsmE NP_699939.2 742701 D 204722 CDS NP_699940.1 23500500 1165205 743547..744920 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01436; glutamate--cysteine ligase 744920 1165205 BRA0763 Brucella suis 1330 glutamate--cysteine ligase NP_699940.1 743547 D 204722 CDS NP_699941.1 23500501 1165206 complement(744986..746521) 1 NC_004311.2 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 746521 xseA 1165206 xseA Brucella suis 1330 exodeoxyribonuclease VII large subunit NP_699941.1 744986 R 204722 CDS NP_699942.1 23500502 1165207 complement(746590..747558) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator 747558 1165207 BRA0765 Brucella suis 1330 LysR family transcriptional regulator NP_699942.1 746590 R 204722 CDS NP_699943.1 23500503 1165208 747725..748027 1 NC_004311.2 hypothetical protein 748027 1165208 BRA0766 Brucella suis 1330 hypothetical protein NP_699943.1 747725 D 204722 CDS NP_699944.1 23500504 1165209 748021..748275 1 NC_004311.2 hypothetical protein 748275 1165209 BRA0767 Brucella suis 1330 hypothetical protein NP_699944.1 748021 D 204722 CDS NP_699945.1 23500505 1165210 748279..749709 1 NC_004311.2 identified by match to PFAM protein family HMM PF00120; glutamine synthetase 749709 1165210 BRA0768 Brucella suis 1330 glutamine synthetase NP_699945.1 748279 D 204722 CDS NP_699946.1 23500506 1165211 749761..750123 1 NC_004311.2 crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 750123 1165211 BRA0769 Brucella suis 1330 hypothetical protein NP_699946.1 749761 D 204722 CDS NP_699947.1 23500507 1165212 750177..751463 1 NC_004311.2 similar to SP:Q9Z3S3; identified by sequence similarity; D-amino acid oxidase 751463 1165212 BRA0770 Brucella suis 1330 D-amino acid oxidase NP_699947.1 750177 D 204722 CDS NP_699948.1 23500508 1165213 complement(751474..751890) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator 751890 1165213 BRA0771 Brucella suis 1330 MarR family transcriptional regulator NP_699948.1 751474 R 204722 CDS NP_699949.1 23500509 1165214 complement(752200..753000) 1 NC_004311.2 hypothetical protein 753000 1165214 BRA0772 Brucella suis 1330 hypothetical protein NP_699949.1 752200 R 204722 CDS NP_699950.1 23500510 1165215 complement(753259..753723) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01037; AsnC family transcriptional regulator 753723 1165215 BRA0773 Brucella suis 1330 AsnC family transcriptional regulator NP_699950.1 753259 R 204722 CDS NP_699951.1 23500511 1165216 754099..754839 1 NC_004311.2 similar to SP:O07942; identified by sequence similarity; AzlC family protein 754839 1165216 BRA0774 Brucella suis 1330 AzlC family protein NP_699951.1 754099 D 204722 CDS NP_699952.1 23500512 1165217 754836..755135 1 NC_004311.2 hypothetical protein 755135 1165217 BRA0775 Brucella suis 1330 hypothetical protein NP_699952.1 754836 D 204722 CDS NP_699953.1 23500513 1165219 complement(756710..757459) 1 NC_004311.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 757459 fabG 1165219 fabG Brucella suis 1330 3-ketoacyl-ACP reductase NP_699953.1 756710 R 204722 CDS NP_699954.1 23500514 1165220 757730..759205 1 NC_004311.2 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 759205 zwf 1165220 zwf Brucella suis 1330 glucose-6-phosphate 1-dehydrogenase NP_699954.1 757730 D 204722 CDS NP_699955.1 23500515 1165221 759334..760032 1 NC_004311.2 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 760032 pgl 1165221 pgl Brucella suis 1330 6-phosphogluconolactonase NP_699955.1 759334 D 204722 CDS NP_699956.1 23500516 1165223 complement(761984..762883) 1 NC_004311.2 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 762883 folD 1165223 folD Brucella suis 1330 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_699956.1 761984 R 204722 CDS NP_699957.1 23500517 1165224 763204..764019 1 NC_004311.2 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 764019 proC 1165224 proC Brucella suis 1330 pyrroline-5-carboxylate reductase NP_699957.1 763204 D 204722 CDS NP_699958.1 23500518 1165226 complement(765607..766437) 1 NC_004311.2 similar to SP:Q53192; identified by sequence similarity; peptide ABC transporter permease 766437 1165226 BRA0784 Brucella suis 1330 peptide ABC transporter permease NP_699958.1 765607 R 204722 CDS NP_699959.1 23500519 1165227 complement(766434..767432) 1 NC_004311.2 similar to SP:Q53191; identified by sequence similarity; peptide ABC transporter permease 767432 1165227 BRA0785 Brucella suis 1330 peptide ABC transporter permease NP_699959.1 766434 R 204722 CDS NP_699960.1 23500520 1165228 complement(767450..769063) 1 NC_004311.2 similar to GP:17741829; identified by sequence similarity; peptide ABC transporter substrate-binding protein 769063 1165228 BRA0786 Brucella suis 1330 peptide ABC transporter substrate-binding protein NP_699960.1 767450 R 204722 CDS NP_699961.1 23500521 1165229 769418..769762 1 NC_004311.2 similar to GP:15141400, and GP:15141400; identified by sequence similarity; hypothetical protein 769762 1165229 BRA0787 Brucella suis 1330 hypothetical protein NP_699961.1 769418 D 204722 CDS NP_699962.1 23500522 1165230 769911..770570 1 NC_004311.2 similar to GP:14277936; identified by sequence similarity; carbonic anhydrase 770570 1165230 BRA0788 Brucella suis 1330 carbonic anhydrase NP_699962.1 769911 D 204722 CDS NP_699963.1 23500523 1165231 complement(770632..771042) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03794; hypothetical protein 771042 1165231 BRA0789 Brucella suis 1330 hypothetical protein NP_699963.1 770632 R 204722 CDS NP_699964.1 23500524 1165232 771237..772892 1 NC_004311.2 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 772892 lysK 1165232 lysK Brucella suis 1330 lysyl-tRNA synthetase NP_699964.1 771237 D 204722 CDS NP_699965.1 23500525 1165233 complement(772980..773939) 1 NC_004311.2 similar to GP:14025443; identified by sequence similarity; hypothetical protein 773939 1165233 BRA0791 Brucella suis 1330 hypothetical protein NP_699965.1 772980 R 204722 CDS NP_699966.1 23500526 1165234 complement(773940..774596) 1 NC_004311.2 similar to GP:15155410; identified by sequence similarity; S24 family peptidase 774596 1165234 BRA0792 Brucella suis 1330 S24 family peptidase NP_699966.1 773940 R 204722 CDS NP_699967.1 23500527 1165235 complement(774834..777050) 1 NC_004311.2 similar to GB:X65488, SP:Q00839, PID:32358, and PID:532037; identified by sequence similarity; fatty oxidation complex subunit alpha 777050 fadB 1165235 fadB Brucella suis 1330 fatty oxidation complex subunit alpha NP_699967.1 774834 R 204722 CDS NP_699968.1 23500528 1165236 complement(777066..778274) 1 NC_004311.2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 778274 1165236 BRA0794 Brucella suis 1330 acetyl-CoA acetyltransferase NP_699968.1 777066 R 204722 CDS NP_699969.1 23500529 1165237 complement(778339..780132) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase 780132 1165237 BRA0795 Brucella suis 1330 acyl-CoA dehydrogenase NP_699969.1 778339 R 204722 CDS NP_699970.1 23500530 1165238 complement(780107..780301) 1 NC_004311.2 hypothetical protein 780301 1165238 BRA0796 Brucella suis 1330 hypothetical protein NP_699970.1 780107 R 204722 CDS NP_699971.1 23500531 1165239 complement(780298..780576) 1 NC_004311.2 hypothetical protein 780576 1165239 BRA0797 Brucella suis 1330 hypothetical protein NP_699971.1 780298 R 204722 CDS NP_699972.1 23500532 1165241 782079..783245 1 NC_004311.2 identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase 783245 1165241 BRA0799 Brucella suis 1330 acyl-CoA dehydrogenase NP_699972.1 782079 D 204722 CDS NP_699973.1 23500533 1165242 complement(783378..784178) 1 NC_004311.2 with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE 784178 nikE 1165242 nikE Brucella suis 1330 nickel transporter ATP-binding protein NikE NP_699973.1 783378 R 204722 CDS NP_699974.1 23500534 1165243 complement(784175..784963) 1 NC_004311.2 with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD 784963 nikD 1165243 nikD Brucella suis 1330 nickel transporter ATP-binding protein NikD NP_699974.1 784175 R 204722 CDS NP_699975.1 23500535 1165244 complement(784960..785832) 1 NC_004311.2 with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC 785832 nikC 1165244 nikC Brucella suis 1330 nickel transporter permease NikC NP_699975.1 784960 R 204722 CDS NP_699976.1 23500536 1165245 complement(785829..786773) 1 NC_004311.2 with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB 786773 nikB 1165245 nikB Brucella suis 1330 nickel transporter permease NikB NP_699976.1 785829 R 204722 CDS NP_699977.1 23500537 1165246 complement(786775..788355) 1 NC_004311.2 similar to GP:12331180, and GP:12331180; identified by sequence similarity; nickel ABC transporter nickel-binding protein 788355 1165246 BRA0804 Brucella suis 1330 nickel ABC transporter nickel-binding protein NP_699977.1 786775 R 204722 CDS NP_699978.1 23500538 1165247 788622..789020 1 NC_004311.2 Inhibits transcription at high concentrations of nickel; nickel responsive regulator 789020 1165247 BRA0805 Brucella suis 1330 nickel responsive regulator NP_699978.1 788622 D 204722 CDS NP_699979.1 23500539 1165248 complement(789031..790575) 1 NC_004311.2 similar to GP:15158051, GB:M25393, SP:P17706, and PID:804750; identified by sequence similarity; UxaA family hydrolase 790575 1165248 BRA0806 Brucella suis 1330 UxaA family hydrolase NP_699979.1 789031 R 204722 CDS NP_699980.1 23500540 1165249 complement(790653..791495) 1 NC_004311.2 similar to GB:U12770, GB:U12774, GB:U12775, GB:L37019, SP:P42127, PID:540073, and PID:608648; identified by sequence similarity; ABC transporter permease 791495 1165249 BRA0807 Brucella suis 1330 ABC transporter permease NP_699980.1 790653 R 204722 CDS NP_699981.1 23500541 1165251 complement(792403..793455) 1 NC_004311.2 similar to GP:9501758; identified by sequence similarity; ABC transporter ATP-binding protein 793455 1165251 BRA0809 Brucella suis 1330 ABC transporter ATP-binding protein NP_699981.1 792403 R 204722 CDS NP_699982.1 23500542 1165252 complement(793533..794714) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01409; ABC transporter periplasmic substrate-binding protein 794714 1165252 BRA0810 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_699982.1 793533 R 204722 CDS NP_699983.1 23500543 1165254 complement(796378..797778) 1 NC_004311.2 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase 797778 1165254 BRA0812 Brucella suis 1330 glucuronate isomerase NP_699983.1 796378 R 204722 CDS NP_699984.1 23500544 1165255 798107..798880 1 NC_004311.2 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 798880 1165255 BRA0813 Brucella suis 1330 GntR family transcriptional regulator NP_699984.1 798107 D 204722 CDS NP_699985.1 23500545 1165256 798941..800146 1 NC_004311.2 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 800146 uxuA 1165256 uxuA Brucella suis 1330 mannonate dehydratase NP_699985.1 798941 D 204722 CDS NP_699986.1 23500546 1165258 complement(803432..804418) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 804418 1165258 BRA0816 Brucella suis 1330 HlyD family secretion protein NP_699986.1 803432 R 204722 CDS NP_699987.1 23500547 1165259 804875..805276 1 NC_004311.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 805276 1165259 BRA0817 Brucella suis 1330 camphor resistance protein CrcB NP_699987.1 804875 D 204722 CDS NP_699988.1 23500548 1165260 805273..805686 1 NC_004311.2 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 805686 1165260 BRA0818 Brucella suis 1330 camphor resistance protein CrcB NP_699988.1 805273 D 204722 CDS NP_699989.1 23500549 1165261 805702..806061 1 NC_004311.2 identified by match to PFAM protein family HMM PF02641; hypothetical protein 806061 1165261 BRA0819 Brucella suis 1330 hypothetical protein NP_699989.1 805702 D 204722 CDS NP_699990.1 23500550 1165262 complement(806116..806511) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 806511 1165262 BRA0820 Brucella suis 1330 MerR family transcriptional regulator NP_699990.1 806116 R 204722 CDS NP_699991.1 23500551 1165263 complement(806805..806942) 1 NC_004311.2 hypothetical protein 806942 1165263 BRA0821 Brucella suis 1330 hypothetical protein NP_699991.1 806805 R 204722 CDS NP_699992.1 23500552 1165264 806941..809682 1 NC_004311.2 identified by match to PFAM protein family HMM PF04012; peptidoglycan-binding protein 809682 1165264 BRA0822 Brucella suis 1330 peptidoglycan-binding protein NP_699992.1 806941 D 204722 CDS NP_699993.1 23500553 1165265 809919..810869 1 NC_004311.2 similar to GP:14025434, and GP:14025434; identified by sequence similarity; hypothetical protein 810869 1165265 BRA0823 Brucella suis 1330 hypothetical protein NP_699993.1 809919 D 204722 CDS NP_699994.1 23500554 1165266 810904..811695 1 NC_004311.2 hypothetical protein 811695 1165266 BRA0824 Brucella suis 1330 hypothetical protein NP_699994.1 810904 D 204722 CDS NP_699995.1 23500555 1165267 complement(811793..812509) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00024; hypothetical protein 812509 1165267 BRA0825 Brucella suis 1330 hypothetical protein NP_699995.1 811793 R 204722 CDS NP_699996.1 23500556 1165268 complement(812506..815061) 1 NC_004311.2 similar to GP:14025425; identified by sequence similarity; DEAD-box ATP dependent DNA helicase 815061 1165268 BRA0826 Brucella suis 1330 DEAD-box ATP dependent DNA helicase NP_699996.1 812506 R 204722 CDS NP_699997.1 23500557 1165269 complement(815071..815217) 1 NC_004311.2 hypothetical protein 815217 1165269 BRA0827 Brucella suis 1330 hypothetical protein NP_699997.1 815071 R 204722 CDS NP_699998.1 23500558 1165270 complement(815313..816335) 1 NC_004311.2 similar to GP:15073435; identified by sequence similarity; hypothetical protein 816335 1165270 BRA0828 Brucella suis 1330 hypothetical protein NP_699998.1 815313 R 204722 CDS NP_699999.1 23500559 1165271 816313..816450 1 NC_004311.2 hypothetical protein 816450 1165271 BRA0829 Brucella suis 1330 hypothetical protein NP_699999.1 816313 D 204722 CDS NP_700000.1 23500560 1165272 complement(816534..816695) 1 NC_004311.2 hypothetical protein 816695 1165272 BRA0830 Brucella suis 1330 hypothetical protein NP_700000.1 816534 R 204722 CDS NP_700001.1 23500561 1165273 816842..817810 1 NC_004311.2 similar to GP:15155334, and GP:15073434; identified by sequence similarity; 2-nitropropane dioxygenase 817810 1165273 BRA0831 Brucella suis 1330 2-nitropropane dioxygenase NP_700001.1 816842 D 204722 CDS NP_700002.1 23500562 1165274 817869..818006 1 NC_004311.2 hypothetical protein 818006 1165274 BRA0832 Brucella suis 1330 hypothetical protein NP_700002.1 817869 D 204722 CDS NP_700003.1 23500563 1165276 818865..819587 1 NC_004311.2 hypothetical protein 819587 1165276 BRA0833 Brucella suis 1330 hypothetical protein NP_700003.1 818865 D 204722 CDS NP_700004.1 23500564 1165277 complement(819594..820094) 1 NC_004311.2 hypothetical protein 820094 1165277 BRA0834 Brucella suis 1330 hypothetical protein NP_700004.1 819594 R 204722 CDS NP_700005.1 23500565 1165278 820233..820349 1 NC_004311.2 hypothetical protein 820349 1165278 BRA0835 Brucella suis 1330 hypothetical protein NP_700005.1 820233 D 204722 CDS NP_700006.1 23500566 1165279 complement(820645..820842) 1 NC_004311.2 similar to GP:7630140; identified by sequence similarity; hypothetical protein 820842 1165279 BRA0836 Brucella suis 1330 hypothetical protein NP_700006.1 820645 R 204722 CDS NP_700007.1 23500567 1165280 820911..821066 1 NC_004311.2 hypothetical protein 821066 1165280 BRA0837 Brucella suis 1330 hypothetical protein NP_700007.1 820911 D 204722 CDS NP_700008.1 23500568 1165281 complement(821860..822000) 1 NC_004311.2 hypothetical protein 822000 1165281 BRA0838 Brucella suis 1330 hypothetical protein NP_700008.1 821860 R 204722 CDS NP_700009.1 23500569 1165282 822161..822793 1 NC_004311.2 identified by match to PFAM protein family HMM PF01420; hypothetical protein 822793 1165282 BRA0839 Brucella suis 1330 hypothetical protein NP_700009.1 822161 D 204722 CDS NP_700010.1 23500570 1165283 822801..824327 1 NC_004311.2 identified by match to PFAM protein family HMM PF01170; type I restriction-modification system, M subunit 824327 hsdM 1165283 hsdM Brucella suis 1330 type I restriction-modification system, M subunit NP_700010.1 822801 D 204722 CDS NP_700011.1 23500571 1165284 824317..825540 1 NC_004311.2 identified by match to PFAM protein family HMM PF03809; type I restriction-modification system, S subunit 825540 hsdS 1165284 hsdS Brucella suis 1330 type I restriction-modification system, S subunit NP_700011.1 824317 D 204722 CDS NP_700012.1 23500572 1165285 825603..828506 1 NC_004311.2 identified by match to PFAM protein family HMM PF03726; type I restriction-modification enzyme, R subunit 828506 hsdR 1165285 hsdR Brucella suis 1330 type I restriction-modification enzyme, R subunit NP_700012.1 825603 D 204722 CDS NP_700013.1 23500573 1165286 828503..829243 1 NC_004311.2 identified by match to PFAM protein family HMM PF01863; hypothetical protein 829243 1165286 BRA0843 Brucella suis 1330 hypothetical protein NP_700013.1 828503 D 204722 CDS NP_700014.1 23500574 1165287 829251..830180 1 NC_004311.2 similar to GP:6900910, GB:J00153, GB:V00491, GB:V00492, GB:J00157, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, PID:537333, GB:J00153, GB:V00516, GB:V00493, GB:V00488, GB:V00489, GB:M24793, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, and PID:537333; identified by sequence similarity; hypothetical protein 830180 1165287 BRA0844 Brucella suis 1330 hypothetical protein NP_700014.1 829251 D 204722 CDS NP_700015.1 23500575 1165289 832598..832909 1 NC_004311.2 similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; IS711, transposase orfA 832909 1165289 BRA0846 Brucella suis 1330 IS711, transposase orfA NP_700015.1 832598 D 204722 CDS NP_700016.1 23500576 1165290 832941..833333 1 NC_004311.2 similar to PIR:PN0685, GB:X07282, SP:P10826, PID:184477, PID:32026, and PID:35883; identified by sequence similarity; IS711, transposase orfB 833333 1165290 BRA0847 Brucella suis 1330 IS711, transposase orfB NP_700016.1 832941 D 204722 CDS NP_700017.1 23500577 1165291 complement(833347..833481) 1 NC_004311.2 hypothetical protein 833481 1165291 BRA0848 Brucella suis 1330 hypothetical protein NP_700017.1 833347 R 204722 CDS NP_700018.1 23500578 1165292 833743..834189 1 NC_004311.2 hypothetical protein 834189 1165292 BRA0849 Brucella suis 1330 hypothetical protein NP_700018.1 833743 D 204722 CDS NP_700019.1 23500579 1165293 834300..835985 1 NC_004311.2 identified by match to PFAM protein family HMM PF03788; hypothetical protein 835985 1165293 BRA0850 Brucella suis 1330 hypothetical protein NP_700019.1 834300 D 204722 CDS NP_700020.1 23500580 1165294 complement(836149..837603) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03819; aminotransferase 837603 1165294 BRA0851 Brucella suis 1330 aminotransferase NP_700020.1 836149 R 204722 CDS NP_700021.1 23500581 1165295 complement(837614..838624) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01472; epimerase 838624 1165295 BRA0852 Brucella suis 1330 epimerase NP_700021.1 837614 R 204722 CDS NP_700022.1 23500582 1165296 complement(838673..839092) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00893; hypothetical protein 839092 1165296 BRA0853 Brucella suis 1330 hypothetical protein NP_700022.1 838673 R 204722 CDS NP_700023.1 23500583 1165298 complement(840460..841899) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01668; hypothetical protein 841899 1165298 BRA0855 Brucella suis 1330 hypothetical protein NP_700023.1 840460 R 204722 CDS NP_700024.1 23500584 1165299 842135..842230 1 NC_004311.2 hypothetical protein 842230 1165299 BRA0856 Brucella suis 1330 hypothetical protein NP_700024.1 842135 D 204722 CDS NP_700025.1 23500585 1165300 complement(842522..843343) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00455; DeoR family transcriptional regulator 843343 1165300 BRA0857 Brucella suis 1330 DeoR family transcriptional regulator NP_700025.1 842522 R 204722 CDS NP_700026.1 23500586 1165301 complement(843551..844498) 1 NC_004311.2 ribose ABC transporter periplasmic D-ribose-binding protein 844498 rbsB-2 1165301 rbsB-2 Brucella suis 1330 ribose ABC transporter periplasmic D-ribose-binding protein NP_700026.1 843551 R 204722 CDS NP_700027.1 23500587 1165302 complement(844665..845705) 1 NC_004311.2 similar to GP:15140211; identified by sequence similarity; ribose ABC transporter permease 845705 rbsC-3 1165302 rbsC-3 Brucella suis 1330 ribose ABC transporter permease NP_700027.1 844665 R 204722 CDS NP_700028.1 23500588 1165303 complement(845729..847273) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00972; ribose ABC transporter ATP-binding protein 847273 rbsA-3 1165303 rbsA-3 Brucella suis 1330 ribose ABC transporter ATP-binding protein NP_700028.1 845729 R 204722 CDS NP_700029.1 23500589 1165304 complement(847270..847926) 1 NC_004311.2 similar to GP:15140209, and GP:15140209; identified by sequence similarity; hypothetical protein 847926 1165304 BRA0861 Brucella suis 1330 hypothetical protein NP_700029.1 847270 R 204722 CDS NP_700030.1 23500590 1165305 847906..848073 1 NC_004311.2 hypothetical protein 848073 1165305 BRA0862 Brucella suis 1330 hypothetical protein NP_700030.1 847906 D 204722 CDS NP_700031.1 23500591 1165306 848525..848677 1 NC_004311.2 hypothetical protein 848677 1165306 BRA0863 Brucella suis 1330 hypothetical protein NP_700031.1 848525 D 204722 CDS NP_700032.1 23500592 1165307 848670..850223 1 NC_004311.2 similar to GP:4204896, and GP:4204896; identified by sequence similarity; erythritol kinase 850223 eryA 1165307 eryA Brucella suis 1330 erythritol kinase NP_700032.1 848670 D 204722 CDS NP_700033.1 23500593 1165308 850236..851744 1 NC_004311.2 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 851744 eryB 1165308 eryB Brucella suis 1330 glycerol-3-phosphate dehydrogenase NP_700033.1 850236 D 204722 CDS NP_700034.1 23500594 1165309 851752..852684 1 NC_004311.2 similar to GP:4204898, and GP:4204898; identified by sequence similarity; D-erythrulose-1-phosphate dehydrogenase 852684 eryC 1165309 eryC Brucella suis 1330 D-erythrulose-1-phosphate dehydrogenase NP_700034.1 851752 D 204722 CDS NP_700035.1 23500595 1165310 852712..853662 1 NC_004311.2 similar to GP:4204899, and GP:4204899; identified by sequence similarity; erythritol transcriptional regulator 853662 eryD 1165310 eryD Brucella suis 1330 erythritol transcriptional regulator NP_700035.1 852712 D 204722 CDS NP_700036.1 23500596 1165311 853750..854514 1 NC_004311.2 similar to GP:4204900; identified by sequence similarity; DeoR family transcriptional regulator 854514 1165311 BRA0868 Brucella suis 1330 DeoR family transcriptional regulator NP_700036.1 853750 D 204722 CDS NP_700037.1 23500597 1165312 854527..855297 1 NC_004311.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 855297 tpiA 1165312 tpiA Brucella suis 1330 triosephosphate isomerase NP_700037.1 854527 D 204722 CDS NP_700038.1 23500598 1165313 855309..855764 1 NC_004311.2 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 855764 1165313 BRA0870 Brucella suis 1330 ribose-5-phosphate isomerase B NP_700038.1 855309 D 204722 CDS NP_700039.1 23500599 1165314 complement(855831..856895) 1 NC_004311.2 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase 856895 fbaA 1165314 fbaA Brucella suis 1330 fructose-1,6-bisphosphate aldolase NP_700039.1 855831 R 204722 CDS NP_700040.1 23500600 1165315 complement(856926..857948) 1 NC_004311.2 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase 857948 fbp 1165315 fbp Brucella suis 1330 fructose-1,6-bisphosphatase NP_700040.1 856926 R 204722 CDS NP_700041.1 23500601 1165316 complement(857945..858184) 1 NC_004311.2 hypothetical protein 858184 1165316 BRA0873 Brucella suis 1330 hypothetical protein NP_700041.1 857945 R 204722 CDS NP_700042.1 23500602 1165317 complement(858382..859071) 1 NC_004311.2 similar to GP:15073394, and GP:15073394; identified by sequence similarity; hypothetical protein 859071 1165317 BRA0874 Brucella suis 1330 hypothetical protein NP_700042.1 858382 R 204722 CDS NP_700043.1 23500603 1165318 complement(859121..860947) 1 NC_004311.2 similar to GP:15076115; identified by sequence similarity; GTP-binding protein TypA 860947 1165318 BRA0875 Brucella suis 1330 GTP-binding protein TypA NP_700043.1 859121 R 204722 CDS NP_700044.1 23500604 1165319 complement(861190..862587) 1 NC_004311.2 similar to GP:17134323; identified by sequence similarity; magnesium transporter 862587 mgtE 1165319 mgtE Brucella suis 1330 magnesium transporter NP_700044.1 861190 R 204722 CDS NP_700045.1 23500605 1165320 complement(862654..862818) 1 NC_004311.2 hypothetical protein 862818 1165320 BRA0877 Brucella suis 1330 hypothetical protein NP_700045.1 862654 R 204722 CDS NP_700046.1 23500606 1165321 862913..864961 1 NC_004311.2 similar to SP:P24171; identified by sequence similarity; peptidyl-dipeptidase Dcp 864961 dcp 1165321 dcp Brucella suis 1330 peptidyl-dipeptidase Dcp NP_700046.1 862913 D 204722 CDS NP_700047.1 23500607 1165322 complement(864990..865343) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00903; glyoxalase 865343 1165322 BRA0879 Brucella suis 1330 glyoxalase NP_700047.1 864990 R 204722 CDS NP_700048.1 23500608 1165323 complement(865343..865549) 1 NC_004311.2 similar to GP:15076201, and GP:15076201; identified by sequence similarity; hypothetical protein 865549 1165323 BRA0880 Brucella suis 1330 hypothetical protein NP_700048.1 865343 R 204722 CDS NP_700049.1 23500609 1165325 866595..866801 1 NC_004311.2 hypothetical protein 866801 1165325 BRA0882 Brucella suis 1330 hypothetical protein NP_700049.1 866595 D 204722 CDS NP_700050.1 23500610 1165326 866866..867471 1 NC_004311.2 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 867471 leuD 1165326 leuD Brucella suis 1330 isopropylmalate isomerase small subunit NP_700050.1 866866 D 204722 CDS NP_700051.1 23500611 1165327 867557..867979 1 NC_004311.2 similar to GP:15076200; identified by sequence similarity; hypothetical protein 867979 1165327 BRA0884 Brucella suis 1330 hypothetical protein NP_700051.1 867557 D 204722 CDS NP_700052.1 23500612 1165328 complement(868030..868452) 1 NC_004311.2 similar to GP:15073893, and SP:O68390; identified by sequence similarity; organic hydroperoxide resistance protein 868452 ohr 1165328 ohr Brucella suis 1330 organic hydroperoxide resistance protein NP_700052.1 868030 R 204722 CDS NP_700053.1 23500613 1165329 868658..869113 1 NC_004311.2 similar to GP:14456720; identified by sequence similarity; MarR family transcriptional regulator 869113 1165329 BRA0886 Brucella suis 1330 MarR family transcriptional regulator NP_700053.1 868658 D 204722 CDS NP_700054.1 23500614 1165330 complement(869177..870211) 1 NC_004311.2 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 870211 asd 1165330 asd Brucella suis 1330 aspartate-semialdehyde dehydrogenase NP_700054.1 869177 R 204722 CDS NP_700055.1 23500615 1165331 870734..872632 1 NC_004311.2 similar to GP:15157678; identified by sequence similarity; major facilitator family transporter 872632 1165331 BRA0888 Brucella suis 1330 major facilitator family transporter NP_700055.1 870734 D 204722 CDS NP_700056.1 23500616 1165332 complement(872690..873742) 1 NC_004311.2 similar to GP:15073366; identified by sequence similarity; ada regulatory protein 873742 1165332 BRA0889 Brucella suis 1330 ada regulatory protein NP_700056.1 872690 R 204722 CDS NP_700057.1 23500617 1165333 complement(873883..874995) 1 NC_004311.2 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 874995 leuB 1165333 leuB Brucella suis 1330 3-isopropylmalate dehydrogenase NP_700057.1 873883 R 204722 CDS NP_700058.1 23500618 1165334 complement(875295..875489) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03966; hypothetical protein 875489 1165334 BRA0891 Brucella suis 1330 hypothetical protein NP_700058.1 875295 R 204722 CDS NP_700059.1 23500619 1165335 complement(875666..876370) 1 NC_004311.2 similar to GP:14024485; identified by sequence similarity; ATP-dependent protease La 876370 1165335 BRA0892 Brucella suis 1330 ATP-dependent protease La NP_700059.1 875666 R 204722 CDS NP_700060.1 23500620 1165336 complement(876434..877408) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03745; thioredoxin 877408 trx-2 1165336 trx-2 Brucella suis 1330 thioredoxin NP_700060.1 876434 R 204722 CDS NP_700061.1 23500621 1165337 complement(877656..878198) 1 NC_004311.2 hypothetical protein 878198 1165337 BRA0894 Brucella suis 1330 hypothetical protein NP_700061.1 877656 R 204722 CDS NP_700062.1 23500622 1165338 complement(878206..878397) 1 NC_004311.2 hypothetical protein 878397 1165338 BRA0895 Brucella suis 1330 hypothetical protein NP_700062.1 878206 R 204722 CDS NP_700063.1 23500623 1165340 complement(878613..879122) 1 NC_004311.2 hypothetical protein 879122 1165340 BRA0896 Brucella suis 1330 hypothetical protein NP_700063.1 878613 R 204722 CDS NP_700064.1 23500624 1165341 878874..879029 1 NC_004311.2 hypothetical protein 879029 1165341 BRA0897 Brucella suis 1330 hypothetical protein NP_700064.1 878874 D 204722 CDS NP_700065.1 23500625 1165342 879194..879604 1 NC_004311.2 similar to GP:15155141; identified by sequence similarity; hypothetical protein 879604 1165342 BRA0898 Brucella suis 1330 hypothetical protein NP_700065.1 879194 D 204722 CDS NP_700066.1 23500626 1165343 complement(879617..880693) 1 NC_004311.2 catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase 880693 arcB 1165343 arcB Brucella suis 1330 ornithine cyclodeaminase NP_700066.1 879617 R 204722 CDS NP_700067.1 23500627 1165344 complement(880732..881652) 1 NC_004311.2 similar to SP:P10366, GB:U02070, GB:X63697, PID:41022, PID:41708, PID:509817, GB:U00096, PID:1736697, and PID:1788330; identified by sequence similarity; arginase 881652 rocF 1165344 rocF Brucella suis 1330 arginase NP_700067.1 880732 R 204722 CDS NP_700068.1 23500628 1165345 881783..882220 1 NC_004311.2 identified by match to PFAM protein family HMM PF02954; AsnC family transcriptional regulator 882220 1165345 BRA0901 Brucella suis 1330 AsnC family transcriptional regulator NP_700068.1 881783 D 204722 CDS NP_700069.1 23500629 1165346 complement(882258..883373) 1 NC_004311.2 similar to GP:15074497; identified by sequence similarity; FMN-binding oxidoreductase 883373 1165346 BRA0902 Brucella suis 1330 FMN-binding oxidoreductase NP_700069.1 882258 R 204722 CDS NP_700070.1 23500630 1165347 complement(883417..883725) 1 NC_004311.2 similar to GP:15074498; identified by sequence similarity; ArsR family transcriptional regulator 883725 1165347 BRA0903 Brucella suis 1330 ArsR family transcriptional regulator NP_700070.1 883417 R 204722 CDS NP_700071.1 23500631 1165348 883943..886246 1 NC_004311.2 similar to SP:P26606, GB:D11109, PID:216433, PID:466645, GB:U00096, and PID:1789924; identified by sequence similarity; tex protein 886246 1165348 BRA0904 Brucella suis 1330 tex protein NP_700071.1 883943 D 204722 CDS NP_700072.1 23500632 1165349 complement(886341..887624) 1 NC_004311.2 similar to GP:15157750; identified by sequence similarity; oxidoreductase 887624 1165349 BRA0905 Brucella suis 1330 oxidoreductase NP_700072.1 886341 R 204722 CDS NP_700073.1 23500633 1165350 complement(887724..888656) 1 NC_004311.2 similar to GP:15076313; identified by sequence similarity; LysR family transcriptional regulator 888656 1165350 BRA0906 Brucella suis 1330 LysR family transcriptional regulator NP_700073.1 887724 R 204722 CDS NP_700074.1 23500634 1165351 888804..890204 1 NC_004311.2 similar to GP:15076314, and GP:15076314; identified by sequence similarity; hypothetical protein 890204 1165351 BRA0907 Brucella suis 1330 hypothetical protein NP_700074.1 888804 D 204722 CDS NP_700075.1 23500635 1165352 890278..891810 1 NC_004311.2 similar to GP:15076316; identified by sequence similarity; aldehyde dehydrogenase 891810 1165352 BRA0908 Brucella suis 1330 aldehyde dehydrogenase NP_700075.1 890278 D 204722 CDS NP_700076.1 23500636 1165353 complement(892034..892918) 1 NC_004311.2 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 892918 purU 1165353 purU Brucella suis 1330 formyltetrahydrofolate deformylase NP_700076.1 892034 R 204722 CDS NP_700077.1 23500637 1165354 complement(893062..893790) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01380; hypothetical protein 893790 1165354 BRA0910 Brucella suis 1330 hypothetical protein NP_700077.1 893062 R 204722 CDS NP_700078.1 23500638 1165355 complement(893798..894964) 1 NC_004311.2 similar to GB:X56652, GB:L05921, GB:M10906, GB:M23698, GB:X51443, SP:P02735, PID:36308, PID:36317, PID:758679, PID:758681, PID:758683, PID:825714, PID:825715, PID:825716, PID:825717, and PID:939926; identified by sequence similarity; N-acetylglucosamine-6-phosphate deacetylase 894964 nagA 1165355 nagA Brucella suis 1330 N-acetylglucosamine-6-phosphate deacetylase NP_700078.1 893798 R 204722 CDS NP_700079.1 23500639 1165356 complement(894961..895992) 1 NC_004311.2 similar to SP:Q9V249; identified by sequence similarity; glucosamine-fructose-6-phosphate aminotransferase 895992 nagB 1165356 nagB Brucella suis 1330 glucosamine-fructose-6-phosphate aminotransferase NP_700079.1 894961 R 204722 CDS NP_700080.1 23500640 1165357 complement(895995..896720) 1 NC_004311.2 similar to GP:15073129; identified by sequence similarity; GntR family transcriptional regulator 896720 1165357 BRA0913 Brucella suis 1330 GntR family transcriptional regulator NP_700080.1 895995 R 204722 CDS NP_700081.1 23500641 1165358 complement(896865..899939) 1 NC_004311.2 similar to GP:17984539; identified by sequence similarity; AcrB/AcrD/AcrF multidrug efflux protein 899939 1165358 BRA0914 Brucella suis 1330 AcrB/AcrD/AcrF multidrug efflux protein NP_700081.1 896865 R 204722 CDS NP_700082.1 23500642 1165359 complement(899936..901042) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00998; secretion protein 901042 1165359 BRA0915 Brucella suis 1330 secretion protein NP_700082.1 899936 R 204722 CDS NP_700083.1 23500643 1165360 complement(901039..902157) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 902157 1165360 BRA0916 Brucella suis 1330 HlyD family secretion protein NP_700083.1 901039 R 204722 CDS NP_700084.1 23500644 1165361 complement(902212..902427) 1 NC_004311.2 hypothetical protein 902427 1165361 BRA0917 Brucella suis 1330 hypothetical protein NP_700084.1 902212 R 204722 CDS NP_700085.1 23500645 1165362 complement(902443..902742) 1 NC_004311.2 similar to GP:15156636, and GP:15156636; identified by sequence similarity; hypothetical protein 902742 1165362 BRA0918 Brucella suis 1330 hypothetical protein NP_700085.1 902443 R 204722 CDS NP_700086.1 23500646 1165363 complement(902739..905051) 1 NC_004311.2 similar to GP:15156635; identified by sequence similarity; molybdopterin-binding oxidoreductase 905051 1165363 BRA0919 Brucella suis 1330 molybdopterin-binding oxidoreductase NP_700086.1 902739 R 204722 CDS NP_700087.1 23500647 1165364 905256..906401 1 NC_004311.2 similar to GP:15141030; identified by sequence similarity; L-lactate dehydrogenase 906401 lldD 1165364 lldD Brucella suis 1330 L-lactate dehydrogenase NP_700087.1 905256 D 204722 CDS NP_700088.1 23500648 1165365 906680..907534 1 NC_004311.2 similar to GP:15075757, and GP:17742129; identified by sequence similarity; outer surface protein 907534 1165365 BRA0921 Brucella suis 1330 outer surface protein NP_700088.1 906680 D 204722 CDS NP_700089.1 23500649 1165366 complement(907682..908149) 1 NC_004311.2 similar to GP:5805087, and GP:5805087; identified by sequence similarity; alanine catabolic operon transcriptional regulator 908149 1165366 BRA0922 Brucella suis 1330 alanine catabolic operon transcriptional regulator NP_700089.1 907682 R 204722 CDS NP_700090.1 23500650 1165367 908399..909589 1 NC_004311.2 identified by match to PFAM protein family HMM PF00842; alanine racemase 909589 alr 1165367 alr Brucella suis 1330 alanine racemase NP_700090.1 908399 D 204722 CDS NP_700091.1 23500651 1165368 909605..910855 1 NC_004311.2 catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 910855 dadA 1165368 dadA Brucella suis 1330 D-amino acid dehydrogenase small subunit NP_700091.1 909605 D 204722 CDS NP_700092.1 23500652 1165369 complement(910898..911446) 1 NC_004311.2 similar to GP:15076318; identified by sequence similarity; transcriptional regulator 911446 1165369 BRA0925 Brucella suis 1330 transcriptional regulator NP_700092.1 910898 R 204722 CDS NP_700093.1 23500653 1165370 911592..912920 1 NC_004311.2 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase 912920 1165370 BRA0926 Brucella suis 1330 beta alanine--pyruvate transaminase NP_700093.1 911592 D 204722 CDS NP_700094.1 23500654 1165371 complement(912991..913734) 1 NC_004311.2 similar to SP:P22773; identified by sequence similarity; histidine utilization repressor 913734 hutC 1165371 hutC Brucella suis 1330 histidine utilization repressor NP_700094.1 912991 R 204722 CDS NP_700095.1 23500655 1165372 complement(913746..915110) 1 NC_004311.2 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase 915110 1165372 BRA0928 Brucella suis 1330 N-formimino-L-glutamate deiminase NP_700095.1 913746 R 204722 CDS NP_700096.1 23500656 1165373 915241..916458 1 NC_004311.2 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 916458 hutI 1165373 hutI Brucella suis 1330 imidazolonepropionase NP_700096.1 915241 D 204722 CDS NP_700097.1 23500657 1165374 916483..918018 1 NC_004311.2 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 918018 hutH 1165374 hutH Brucella suis 1330 histidine ammonia-lyase NP_700097.1 916483 D 204722 CDS NP_700098.1 23500658 1165375 918020..918820 1 NC_004311.2 similar to GP:15159359; identified by sequence similarity; formiminoglutamase 918820 hutG 1165375 hutG Brucella suis 1330 formiminoglutamase NP_700098.1 918020 D 204722 CDS NP_700099.1 23500659 1165376 918831..920504 1 NC_004311.2 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 920504 hutU 1165376 hutU Brucella suis 1330 urocanate hydratase NP_700099.1 918831 D 204722 CDS NP_700100.1 23500660 1165377 920511..921134 1 NC_004311.2 similar to GP:15075729, and GP:15075729; identified by sequence similarity; hypothetical protein 921134 1165377 BRA0933 Brucella suis 1330 hypothetical protein NP_700100.1 920511 D 204722 CDS NP_700101.1 23500661 1165378 921222..922103 1 NC_004311.2 catalyzes the transamination of D-amino acids and their alpha-keto acids; D-amino acid aminotransferase 922103 1165378 BRA0934 Brucella suis 1330 D-amino acid aminotransferase NP_700101.1 921222 D 204722 CDS NP_700102.1 23500662 1165379 complement(922254..923444) 1 NC_004311.2 similar to GB:M33819; identified by sequence similarity; sugar ABC transporter permease 923444 1165379 BRA0935 Brucella suis 1330 sugar ABC transporter permease NP_700102.1 922254 R 204722 CDS NP_700103.1 23500663 1165380 complement(923444..925033) 1 NC_004311.2 similar to GP:15485215; identified by sequence similarity; sugar ABC transporter ATP-binding protein 925033 1165380 BRA0936 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_700103.1 923444 R 204722 CDS NP_700104.1 23500664 1165381 complement(925179..926240) 1 NC_004311.2 similar to GB:D14697, GB:J05262, GB:M29863, SP:P14324, PID:182399, PID:182405, PID:285965, and PID:285965; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 926240 1165381 BRA0937 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_700104.1 925179 R 204722 CDS NP_700105.1 23500665 1165382 complement(926389..927021) 1 NC_004311.2 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase 927021 1165382 BRA0938 Brucella suis 1330 2-dehydro-3-deoxy-6-phosphogalactonate aldolase NP_700105.1 926389 R 204722 CDS NP_700106.1 23500666 1165383 complement(927018..927947) 1 NC_004311.2 similar to GP:15155670, GB:M38180, GB:X55997, GB:M27137, SP:P14060, SP:P26439, PID:177191, PID:177196, PID:179468, PID:23862, PID:287844, and PID:306889; identified by sequence similarity; 2-dehydro-3-deoxygalactonokinase 927947 dgoK 1165383 dgoK Brucella suis 1330 2-dehydro-3-deoxygalactonokinase NP_700106.1 927018 R 204722 CDS NP_700107.1 23500667 1165384 complement(927962..929767) 1 NC_004311.2 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase 929767 1165384 BRA0940 Brucella suis 1330 dihydroxy-acid dehydratase NP_700107.1 927962 R 204722 CDS NP_700108.1 23500668 1165385 complement(929864..930799) 1 NC_004311.2 similar to GP:15156146, GB:L09118, GB:L23205, SP:Q05940, PID:1220370, PID:1770738, PID:292335, PID:296189, and PID:349712; identified by sequence similarity; D-galactose 1-dehydrogenase 930799 1165385 BRA0941 Brucella suis 1330 D-galactose 1-dehydrogenase NP_700108.1 929864 R 204722 CDS NP_700109.1 23500669 1165386 complement(930808..931800) 1 NC_004311.2 hypothetical protein 931800 1165386 BRA0942 Brucella suis 1330 hypothetical protein NP_700109.1 930808 R 204722 CDS NP_700110.1 23500670 1165387 932070..932363 1 NC_004311.2 hypothetical protein 932363 1165387 BRA0943 Brucella suis 1330 hypothetical protein NP_700110.1 932070 D 204722 CDS NP_700111.1 23500671 1165389 complement(933065..934750) 1 NC_004311.2 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit; thiamine pyrophosphate protein 934750 1165389 BRA0945 Brucella suis 1330 thiamine pyrophosphate protein NP_700111.1 933065 R 204722 CDS NP_700112.1 23500672 1165390 934974..935141 1 NC_004311.2 hypothetical protein 935141 1165390 BRA0946 Brucella suis 1330 hypothetical protein NP_700112.1 934974 D 204722 CDS NP_700113.1 23500673 1165391 935166..936722 1 NC_004311.2 intracellular enzymes acting on low molecular weight D-amino acid amides, esters and oligopeptides containing D-amino acids; these proteases release the N-terminal D-amino acid from a peptide, and show higher affinity for D-Ala, D-Ser or D-Thr; no preference for the stereochemistry of the second amino acid; D-aminopeptidase 936722 1165391 BRA0947 Brucella suis 1330 D-aminopeptidase NP_700113.1 935166 D 204722 CDS NP_700114.1 23500674 1165392 complement(936753..937772) 1 NC_004311.2 similar to GP:15075720, and SP:P45766; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 937772 1165392 BRA0948 Brucella suis 1330 amino acid ABC transporter substrate-binding protein NP_700114.1 936753 R 204722 CDS NP_700115.1 23500675 1165393 complement(937876..940947) 1 NC_004311.2 similar to GP:15075719; identified by sequence similarity; hypothetical protein 940947 1165393 BRA0949 Brucella suis 1330 hypothetical protein NP_700115.1 937876 R 204722 CDS NP_700116.1 23500676 1165394 complement(941041..941184) 1 NC_004311.2 hypothetical protein 941184 1165394 BRA0950 Brucella suis 1330 hypothetical protein NP_700116.1 941041 R 204722 CDS NP_700117.1 23500677 1165395 941198..941638 1 NC_004311.2 similar to GP:15075718; identified by sequence similarity; AsnC family transcriptional regulator 941638 1165395 BRA0951 Brucella suis 1330 AsnC family transcriptional regulator NP_700117.1 941198 D 204722 CDS NP_700118.1 23500678 1165396 complement(941854..942768) 1 NC_004311.2 similar to GP:15075996; identified by sequence similarity; LysR family transcriptional regulator 942768 1165396 BRA0952 Brucella suis 1330 LysR family transcriptional regulator NP_700118.1 941854 R 204722 CDS NP_700119.1 23500679 1165397 943033..944238 1 NC_004311.2 similar to GP:15159145, and GP:15075607; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 944238 1165397 BRA0953 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_700119.1 943033 D 204722 CDS NP_700120.1 23500680 1165398 944251..945066 1 NC_004311.2 similar to GP:15159144; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 945066 1165398 BRA0954 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_700120.1 944251 D 204722 CDS NP_700121.1 23500681 1165399 945059..945784 1 NC_004311.2 similar to GP:15075999, and SP:P22731; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein LivF 945784 1165399 BRA0955 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein LivF NP_700121.1 945059 D 204722 CDS NP_700122.1 23500682 1165400 945789..946676 1 NC_004311.2 similar to GP:15076000; identified by sequence similarity; branched-chain amino acid ABC transporter permease 946676 1165400 BRA0956 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_700122.1 945789 D 204722 CDS NP_700123.1 23500683 1165401 946678..947673 1 NC_004311.2 similar to GP:15159141; identified by sequence similarity; branched-chain amino acid ABC transporter permease 947673 1165401 BRA0957 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_700123.1 946678 D 204722 CDS NP_700124.1 23500684 1165402 947737..949335 1 NC_004311.2 similar to GP:15076002; identified by sequence similarity; GMC family oxidoreductase 949335 1165402 BRA0958 Brucella suis 1330 GMC family oxidoreductase NP_700124.1 947737 D 204722 CDS NP_700125.1 23500685 1165403 949332..949475 1 NC_004311.2 hypothetical protein 949475 1165403 BRA0959 Brucella suis 1330 hypothetical protein NP_700125.1 949332 D 204722 CDS NP_700126.1 23500686 1165404 949569..950405 1 NC_004311.2 identified by match to PFAM protein family HMM PF03734; YaeC family lipoprotein 950405 1165404 BRA0960 Brucella suis 1330 YaeC family lipoprotein NP_700126.1 949569 D 204722 CDS NP_700127.1 23500687 1165405 950870..951928 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00972; ABC transporter ATP-binding protein 951928 1165405 BRA0961 Brucella suis 1330 ABC transporter ATP-binding protein NP_700127.1 950870 D 204722 CDS NP_700128.1 23500688 1165406 951909..952574 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01594; ABC transporter permease 952574 1165406 BRA0962 Brucella suis 1330 ABC transporter permease NP_700128.1 951909 D 204722 CDS NP_700129.1 23500689 1165407 complement(952587..952994) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00903; glyoxalase 952994 1165407 BRA0963 Brucella suis 1330 glyoxalase NP_700129.1 952587 R 204722 CDS NP_700130.1 23500690 1165408 complement(953086..953973) 1 NC_004311.2 similar to GP:15075882; identified by sequence similarity; TPR domain-containing protein 953973 1165408 BRA0964 Brucella suis 1330 TPR domain-containing protein NP_700130.1 953086 R 204722 CDS NP_700131.1 23500691 1165409 954067..954228 1 NC_004311.2 hypothetical protein 954228 1165409 BRA0965 Brucella suis 1330 hypothetical protein NP_700131.1 954067 D 204722 CDS NP_700132.1 23500692 1165410 complement(954512..954739) 1 NC_004311.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 954739 rpsU 1165410 rpsU Brucella suis 1330 30S ribosomal protein S21 NP_700132.1 954512 R 204722 CDS NP_700133.1 23500693 1165411 955092..956288 1 NC_004311.2 similar to GP:15156967, and GP:15156967; identified by sequence similarity; hypothetical protein 956288 1165411 BRA0967 Brucella suis 1330 hypothetical protein NP_700133.1 955092 D 204722 CDS NP_700134.1 23500694 1165412 complement(956363..956839) 1 NC_004311.2 similar to GB:X60708, GB:U13710, GB:U13711, GB:U13712, GB:U13713, GB:U13714, GB:U13715, GB:U13716, GB:U13717, GB:U13718, GB:U13719, GB:U13720, GB:U13721, GB:U13722, GB:U13723, GB:U13724, GB:U13725, GB:U13726, GB:U13727, GB:U13728, GB:U13729, GB:U13730, GB:U13731, GB:U13732, GB:U13733, GB:U13734, GB:U13735, GB:S79876, SP:P27487, PID:180083, PID:181570, PID:35336, and PID:535388; identified by sequence similarity; nodulation protein N 956839 1165412 BRA0968 Brucella suis 1330 nodulation protein N NP_700134.1 956363 R 204722 CDS NP_700135.1 23500695 1165413 complement(956914..957585) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01662; HAD superfamily hydrolase 957585 1165413 BRA0969 Brucella suis 1330 HAD superfamily hydrolase NP_700135.1 956914 R 204722 CDS NP_700136.1 23500696 1165414 957781..959097 1 NC_004311.2 identified by match to PFAM protein family HMM PF03447; oxidoreductase 959097 1165414 BRA0970 Brucella suis 1330 oxidoreductase NP_700136.1 957781 D 204722 CDS NP_700137.1 23500697 1165415 complement(959183..960583) 1 NC_004311.2 similar to GP:15075885, GB:M64979, GB:L14754, GB:L24544, SP:P38935, PID:401776, and PID:908917; identified by sequence similarity; NAD(P) transhydrogenase subunit beta 960583 pntB 1165415 pntB Brucella suis 1330 NAD(P) transhydrogenase subunit beta NP_700137.1 959183 R 204722 CDS NP_700138.1 23500698 1165416 complement(960596..961015) 1 NC_004311.2 similar to GP:15075886, GB:V00497, GB:M25113, GB:U01317, GB:M36640, GB:M25660, GB:A01592, GB:A18171, GB:M11428, GB:M25079, GB:V00500, GB:L48213, GB:U20223, GB:V00499, GB:V00498, SP:P02023, SP:P02042, PID:1066755, PID:1066758, PID:1066761, PID:1066764, PID:1066767, PID:1066770, PID:1066773, PID:1066776, PID:1066779, and PID:455998; identified by sequence similarity; NAD(P) transhydrogenase subunit alpha 961015 pntAB 1165416 pntAB Brucella suis 1330 NAD(P) transhydrogenase subunit alpha NP_700138.1 960596 R 204722 CDS NP_700139.1 23500699 1165417 complement(961015..962304) 1 NC_004311.2 similar to GB:X70218, SP:P33172, and PID:312814; identified by sequence similarity; NAD(P) transhydrogenase subunit alpha 962304 pntA 1165417 pntA Brucella suis 1330 NAD(P) transhydrogenase subunit alpha NP_700139.1 961015 R 204722 CDS NP_700140.1 23500700 1165418 complement(962530..962754) 1 NC_004311.2 similar to GP:15075888, and GP:15075888; identified by sequence similarity; hypothetical protein 962754 1165418 BRA0974 Brucella suis 1330 hypothetical protein NP_700140.1 962530 R 204722 CDS NP_700141.1 23500701 1165419 962784..962918 1 NC_004311.2 hypothetical protein 962918 1165419 BRA0975 Brucella suis 1330 hypothetical protein NP_700141.1 962784 D 204722 CDS NP_700142.1 23500702 1165420 complement(962958..963704) 1 NC_004311.2 hypothetical protein 963704 1165420 BRA0976 Brucella suis 1330 hypothetical protein NP_700142.1 962958 R 204722 CDS NP_700143.1 23500703 1165421 complement(963812..963922) 1 NC_004311.2 hypothetical protein 963922 1165421 BRA0977 Brucella suis 1330 hypothetical protein NP_700143.1 963812 R 204722 CDS NP_700144.1 23500704 1165423 complement(965445..967742) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein 967742 1165423 BRA0979 Brucella suis 1330 GGDEF domain-containing protein NP_700144.1 965445 R 204722 CDS NP_700145.1 23500705 1165424 complement(967987..968127) 1 NC_004311.2 hypothetical protein 968127 1165424 BRA0980 Brucella suis 1330 hypothetical protein NP_700145.1 967987 R 204722 CDS NP_700146.1 23500706 1165425 complement(968108..968857) 1 NC_004311.2 similar to GP:12698385, GB:M62800, GB:U01882, SP:P19474, PID:337485, PID:338490, PID:665918, and PID:747927; identified by sequence similarity; 2-deoxy-D-gluconate 3-dehydrogenase 968857 1165425 BRA0981 Brucella suis 1330 2-deoxy-D-gluconate 3-dehydrogenase NP_700146.1 968108 R 204722 CDS NP_700147.1 23500707 1165426 969092..969928 1 NC_004311.2 identified by match to PFAM protein family HMM PF00117; glutamine amidotransferase, class I 969928 1165426 BRA0982 Brucella suis 1330 glutamine amidotransferase, class I NP_700147.1 969092 D 204722 CDS NP_700148.1 23500708 1165427 complement(969954..970928) 1 NC_004311.2 Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase 970928 1165427 BRA0983 Brucella suis 1330 glycerate dehydrogenase NP_700148.1 969954 R 204722 CDS NP_700149.1 23500709 1165428 complement(971014..972033) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01481; transcriptional regulator 972033 1165428 BRA0984 Brucella suis 1330 transcriptional regulator NP_700149.1 971014 R 204722 CDS NP_700150.1 23500710 1165430 972850..973620 1 NC_004311.2 similar to GP:15075894, GB:X74863, SP:P52954, PID:1617116, and PID:510998; identified by sequence similarity; creatinine amidohydrolase 973620 1165430 BRA0986 Brucella suis 1330 creatinine amidohydrolase NP_700150.1 972850 D 204722 CDS NP_700151.1 23500711 1165431 973856..974980 1 NC_004311.2 similar to GP:15075895; identified by sequence similarity; cobalamin synthesis protein/P47K family protein 974980 1165431 BRA0987 Brucella suis 1330 cobalamin synthesis protein/P47K family protein NP_700151.1 973856 D 204722 CDS NP_700152.1 23500712 1165432 975099..976073 1 NC_004311.2 identified by match to PFAM protein family HMM PF00400; hypothetical protein 976073 1165432 BRA0988 Brucella suis 1330 hypothetical protein NP_700152.1 975099 D 204722 CDS NP_700153.1 23500713 1165433 complement(976190..977056) 1 NC_004311.2 similar to GP:15075513, and GP:15075513; identified by sequence similarity; hypothetical protein 977056 1165433 BRA0989 Brucella suis 1330 hypothetical protein NP_700153.1 976190 R 204722 CDS NP_700154.1 23500714 1165434 977479..978438 1 NC_004311.2 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 978438 1165434 BRA0990 Brucella suis 1330 sulfite oxidase subunit YedY NP_700154.1 977479 D 204722 CDS NP_700155.1 23500715 1165435 978440..979102 1 NC_004311.2 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 979102 1165435 BRA0991 Brucella suis 1330 sulfite oxidase subunit YedZ NP_700155.1 978440 D 204722 CDS NP_700156.1 23500716 1165436 complement(979310..979654) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00004; hypothetical protein 979654 1165436 BRA0992 Brucella suis 1330 hypothetical protein NP_700156.1 979310 R 204722 CDS NP_700157.1 23500717 1165437 complement(979729..980682) 1 NC_004311.2 similar to GP:15139890; identified by sequence similarity; ribose ABC transporter permease 980682 rbsC-4 1165437 rbsC-4 Brucella suis 1330 ribose ABC transporter permease NP_700157.1 979729 R 204722 CDS NP_700158.1 23500718 1165438 complement(980679..981638) 1 NC_004311.2 similar to SP:P04984; identified by sequence similarity; ribose ABC transporter permease 981638 rbsC-5 1165438 rbsC-5 Brucella suis 1330 ribose ABC transporter permease NP_700158.1 980679 R 204722 CDS NP_700159.1 23500719 1165439 complement(981638..983146) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00955; ribose ABC transporter ATP-binding protein 983146 rbsA-4 1165439 rbsA-4 Brucella suis 1330 ribose ABC transporter ATP-binding protein NP_700159.1 981638 R 204722 CDS NP_700160.1 23500720 1165440 complement(983179..984246) 1 NC_004311.2 similar to GP:15139893; identified by sequence similarity; ribose ABC transporter periplasmic D-ribose-binding protein 984246 rbsB-3 1165440 rbsB-3 Brucella suis 1330 ribose ABC transporter periplasmic D-ribose-binding protein NP_700160.1 983179 R 204722 CDS NP_700161.1 23500721 1165441 984548..985342 1 NC_004311.2 similar to GP:11275975; identified by sequence similarity; IclR family transcriptional regulator 985342 1165441 BRA0997 Brucella suis 1330 IclR family transcriptional regulator NP_700161.1 984548 D 204722 CDS NP_700162.1 23500722 1165442 complement(985436..986617) 1 NC_004311.2 similar to GP:5420003, and GP:5420003; identified by sequence similarity; hypothetical protein 986617 1165442 BRA0998 Brucella suis 1330 hypothetical protein NP_700162.1 985436 R 204722 CDS NP_700163.1 23500723 1165443 complement(986785..988815) 1 NC_004311.2 similar to GB:M90413, PID:153311, GB:Z22551, GB:D13629, GB:L25616, PID:285985, and PID:409466; identified by sequence similarity; nosA protein 988815 1165443 BRA0999 Brucella suis 1330 nosA protein NP_700163.1 986785 R 204722 CDS NP_700164.1 23500724 1165444 complement(988912..989319) 1 NC_004311.2 similar to GP:15156545, and GP:15156545; identified by sequence similarity; hypothetical protein 989319 1165444 BRA1000 Brucella suis 1330 hypothetical protein NP_700164.1 988912 R 204722 CDS NP_700165.1 23500725 1165445 complement(989472..989858) 1 NC_004311.2 similar to SP:P47233; identified by sequence similarity; extradiol ring-cleaving dioxygenase 989858 1165445 BRA1001 Brucella suis 1330 extradiol ring-cleaving dioxygenase NP_700165.1 989472 R 204722 CDS NP_700166.1 23500726 1165446 complement(990041..990646) 1 NC_004311.2 similar to SP:P81065, GB:J00117, GB:K03180, GB:K03187, GB:K03188, GB:K03189, GB:X00265, GB:X00266, GB:K03183, GB:K00092, GB:K03182, SP:P01229, SP:P01233, PID:1335012, PID:1335075, PID:180437, PID:180444, and PID:180453; identified by sequence similarity; glutathione S-transferase 990646 1165446 BRA1002 Brucella suis 1330 glutathione S-transferase NP_700166.1 990041 R 204722 CDS NP_700167.1 23500727 1165447 complement(990750..992051) 1 NC_004311.2 hypothetical protein 992051 1165447 BRA1003 Brucella suis 1330 hypothetical protein NP_700167.1 990750 R 204722 CDS NP_700168.1 23500728 1165448 complement(992222..993331) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03772; GGDEF domain-containing protein 993331 1165448 BRA1004 Brucella suis 1330 GGDEF domain-containing protein NP_700168.1 992222 R 204722 CDS NP_700169.1 23500729 1165449 complement(993566..994798) 1 NC_004311.2 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase 994798 1165449 BRA1005 Brucella suis 1330 hydroxyglutarate oxidase NP_700169.1 993566 R 204722 CDS NP_700170.1 23500730 1165450 994954..995952 1 NC_004311.2 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 995952 1165450 BRA1006 Brucella suis 1330 DNA polymerase III subunit epsilon NP_700170.1 994954 D 204722 CDS NP_700171.1 23500731 1165452 complement(997431..998279) 1 NC_004311.2 similar to GP:15160122; identified by sequence similarity; peptide ABC transporter ATP-binding protein 998279 1165452 BRA1008 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_700171.1 997431 R 204722 CDS NP_700172.1 23500732 1165453 complement(998276..999301) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01188; peptide ABC transporter ATP-binding protein 999301 1165453 BRA1009 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_700172.1 998276 R 204722 CDS NP_700173.1 23500733 1165454 complement(999298..1000158) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03772; peptide ABC transporter permease 1000158 1165454 BRA1010 Brucella suis 1330 peptide ABC transporter permease NP_700173.1 999298 R 204722 CDS NP_700174.1 23500734 1165455 complement(1000155..1001108) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease 1001108 1165455 BRA1011 Brucella suis 1330 peptide ABC transporter permease NP_700174.1 1000155 R 204722 CDS NP_700175.1 23500735 1165456 complement(1001206..1002684) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01698; ABC transporter periplasmic substrate-binding protein 1002684 1165456 BRA1012 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_700175.1 1001206 R 204722 CDS NP_700176.1 23500736 1165457 complement(1002707..1003465) 1 NC_004311.2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 1003465 fabG 1165457 fabG Brucella suis 1330 3-ketoacyl-ACP reductase NP_700176.1 1002707 R 204722 CDS NP_700177.1 23500737 1165458 complement(1003500..1004993) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01682; aldehyde dehydrogenase 1004993 1165458 BRA1014 Brucella suis 1330 aldehyde dehydrogenase NP_700177.1 1003500 R 204722 CDS NP_700178.1 23500738 1165459 complement(1004977..1005663) 1 NC_004311.2 identified by match to PFAM protein family HMM PF01325; GntR family transcriptional regulator 1005663 1165459 BRA1015 Brucella suis 1330 GntR family transcriptional regulator NP_700178.1 1004977 R 204722 CDS NP_700179.1 23500739 1165460 complement(1005763..1005909) 1 NC_004311.2 hypothetical protein 1005909 1165460 BRA1016 Brucella suis 1330 hypothetical protein NP_700179.1 1005763 R 204722 CDS NP_700180.1 23500740 1165461 1006033..1007412 1 NC_004311.2 similar to SP:P76269; identified by sequence similarity; transporter 1007412 1165461 BRA1017 Brucella suis 1330 transporter NP_700180.1 1006033 D 204722 CDS NP_700181.1 23500741 1165463 1007806..1008873 1 NC_004311.2 hypothetical protein 1008873 1165463 BRA1018 Brucella suis 1330 hypothetical protein NP_700181.1 1007806 D 204722 CDS NP_700182.1 23500742 1165464 complement(1008927..1009271) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00004; hypothetical protein 1009271 1165464 BRA1019 Brucella suis 1330 hypothetical protein NP_700182.1 1008927 R 204722 CDS NP_700183.1 23500743 1165465 1009354..1009578 1 NC_004311.2 hypothetical protein 1009578 1165465 BRA1020 Brucella suis 1330 hypothetical protein NP_700183.1 1009354 D 204722 CDS NP_700184.1 23500744 1165466 1009579..1009713 1 NC_004311.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1009713 rpmH 1165466 rpmH Brucella suis 1330 50S ribosomal protein L34 NP_700184.1 1009579 D 204722 CDS NP_700185.1 23500745 1165467 1009751..1010188 1 NC_004311.2 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1010188 rnpA 1165467 rnpA Brucella suis 1330 ribonuclease P NP_700185.1 1009751 D 204722 CDS NP_700186.1 23500746 1165468 1010178..1012010 1 NC_004311.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1012010 1165468 BRA1023 Brucella suis 1330 inner membrane protein translocase component YidC NP_700186.1 1010178 D 204722 CDS NP_700187.1 23500747 1165469 1012052..1012855 1 NC_004311.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1012855 engB 1165469 engB Brucella suis 1330 ribosome biogenesis GTP-binding protein YsxC NP_700187.1 1012052 D 204722 CDS NP_700188.1 23500748 1165470 1013026..1013916 1 NC_004311.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1013916 argB 1165470 argB Brucella suis 1330 acetylglutamate kinase NP_700188.1 1013026 D 204722 CDS NP_700189.1 23500749 1165471 1013990..1014694 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 1014694 1165471 BRA1026 Brucella suis 1330 HAD superfamily hydrolase NP_700189.1 1013990 D 204722 CDS NP_700190.1 23500750 1165472 complement(1014756..1015586) 1 NC_004311.2 similar to GP:15073363, and GP:15073363; identified by sequence similarity; hypothetical protein 1015586 1165472 BRA1027 Brucella suis 1330 hypothetical protein NP_700190.1 1014756 R 204722 CDS NP_700191.1 23500751 1165473 1015805..1016659 1 NC_004311.2 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1016659 dapD 1165473 dapD Brucella suis 1330 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_700191.1 1015805 D 204722 CDS NP_700192.1 23500752 1165474 complement(1016803..1017357) 1 NC_004311.2 hypothetical protein 1017357 1165474 BRA1029 Brucella suis 1330 hypothetical protein NP_700192.1 1016803 R 204722 CDS NP_700193.1 23500753 1165475 1017510..1017602 1 NC_004311.2 hypothetical protein 1017602 1165475 BRA1030 Brucella suis 1330 hypothetical protein NP_700193.1 1017510 D 204722 CDS NP_700194.1 23500754 1165476 1017642..1018829 1 NC_004311.2 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1018829 dapE 1165476 dapE Brucella suis 1330 succinyl-diaminopimelate desuccinylase NP_700194.1 1017642 D 204722 CDS NP_700195.1 23500755 1165477 1018892..1019497 1 NC_004311.2 similar to GP:15073353; identified by sequence similarity; hypothetical protein 1019497 1165477 BRA1032 Brucella suis 1330 hypothetical protein NP_700195.1 1018892 D 204722 CDS YP_002519393.1 221090245 1165478 complement(1019672..1020427) 1 NC_004311.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 1020427 truA 1165478 truA Brucella suis 1330 tRNA pseudouridine synthase A YP_002519393.1 1019672 R 204722 CDS NP_700196.1 23500756 1165479 complement(1020431..1021351) 1 NC_004311.2 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase 1021351 fmt 1165479 fmt Brucella suis 1330 methionyl-tRNA formyltransferase NP_700196.1 1020431 R 204722 CDS NP_700197.1 23500757 1165480 complement(1021351..1021914) 1 NC_004311.2 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1021914 def 1165480 def Brucella suis 1330 peptide deformylase NP_700197.1 1021351 R 204722 CDS NP_700198.1 23500758 1165481 1021981..1023204 1 NC_004311.2 similar to GP:14024818; identified by sequence similarity; hypothetical protein 1023204 1165481 BRA1036 Brucella suis 1330 hypothetical protein NP_700198.1 1021981 D 204722 CDS NP_700199.1 23500759 1165482 complement(1023433..1023738) 1 NC_004311.2 similar to GP:15073194, and GP:15073194; identified by sequence similarity; hypothetical protein 1023738 1165482 BRA1037 Brucella suis 1330 hypothetical protein NP_700199.1 1023433 R 204722 CDS NP_700200.1 23500760 1165483 1023847..1024128 1 NC_004311.2 hypothetical protein 1024128 1165483 BRA1038 Brucella suis 1330 hypothetical protein NP_700200.1 1023847 D 204722 CDS NP_700201.1 23500761 1165484 complement(1024377..1026185) 1 NC_004311.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1026185 lepA 1165484 lepA Brucella suis 1330 GTP-binding protein LepA NP_700201.1 1024377 R 204722 CDS NP_700202.1 23500762 1165485 complement(1026182..1026313) 1 NC_004311.2 hypothetical protein 1026313 1165485 BRA1040 Brucella suis 1330 hypothetical protein NP_700202.1 1026182 R 204722 CDS NP_700203.1 23500763 1165486 1026349..1027335 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01181; NADH-ubiquinone oxidoreductase 1027335 1165486 BRA1041 Brucella suis 1330 NADH-ubiquinone oxidoreductase NP_700203.1 1026349 D 204722 CDS NP_700204.1 23500764 1165487 complement(1027436..1028242) 1 NC_004311.2 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 1028242 uppP 1165487 uppP Brucella suis 1330 undecaprenyl pyrophosphate phosphatase NP_700204.1 1027436 R 204722 CDS NP_700205.1 23500765 1165488 complement(1028247..1028450) 1 NC_004311.2 hypothetical protein 1028450 1165488 BRA1043 Brucella suis 1330 hypothetical protein NP_700205.1 1028247 R 204722 CDS NP_700206.1 23500766 1165489 1028498..1029190 1 NC_004311.2 identified by match to PFAM protein family HMM PF03578; glutathione S-transferase 1029190 1165489 BRA1044 Brucella suis 1330 glutathione S-transferase NP_700206.1 1028498 D 204722 CDS NP_700207.1 23500767 1165490 1029171..1030367 1 NC_004311.2 identified by match to PFAM protein family HMM PF00037; (Fe-S)-binding protein 1030367 1165490 BRA1045 Brucella suis 1330 (Fe-S)-binding protein NP_700207.1 1029171 D 204722 CDS NP_700208.1 23500768 1165491 1030369..1031238 1 NC_004311.2 similar to GP:15073254; identified by sequence similarity; hypothetical protein 1031238 1165491 BRA1046 Brucella suis 1330 hypothetical protein NP_700208.1 1030369 D 204722 CDS NP_700209.1 23500769 1165492 1031239..1032261 1 NC_004311.2 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1032261 mepA 1165492 mepA Brucella suis 1330 penicillin-insensitive murein endopeptidase NP_700209.1 1031239 D 204722 CDS NP_700210.1 23500770 1165493 1032414..1032791 1 NC_004311.2 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1032791 mgsA 1165493 mgsA Brucella suis 1330 methylglyoxal synthase NP_700210.1 1032414 D 204722 CDS NP_700211.1 23500771 1165494 1032872..1033903 1 NC_004311.2 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1033903 glk 1165494 glk Brucella suis 1330 glucokinase NP_700211.1 1032872 D 204722 CDS NP_700212.1 23500772 1165495 1034130..1035959 1 NC_004311.2 similar to GB:U09086, GB:U09087, GB:U09088, GB:S76736, SP:P42166, SP:P42167, PID:508725, PID:508727, PID:508729, PID:885683, and PID:885684; identified by sequence similarity; ABC transporter ATP-binding/permease 1035959 1165495 BRA1050 Brucella suis 1330 ABC transporter ATP-binding/permease NP_700212.1 1034130 D 204722 CDS NP_700213.1 23500773 1165496 1035989..1036795 1 NC_004311.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1036795 dapB 1165496 dapB Brucella suis 1330 dihydrodipicolinate reductase NP_700213.1 1035989 D 204722 CDS NP_700214.1 23500774 1165497 1036832..1037452 1 NC_004311.2 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1037452 gpm 1165497 gpm Brucella suis 1330 phosphoglyceromutase NP_700214.1 1036832 D 204722 CDS NP_700215.1 23500775 1165499 1037873..1039624 1 NC_004311.2 identified by match to PFAM protein family HMM PF03663; hypothetical protein 1039624 1165499 BRA1053 Brucella suis 1330 hypothetical protein NP_700215.1 1037873 D 204722 CDS NP_700216.1 23500776 1165500 1040135..1040758 1 NC_004311.2 similar to GP:3128327, GB:U05040, and PID:460152; identified by sequence similarity; nitroreductase 1040758 1165500 BRA1054 Brucella suis 1330 nitroreductase NP_700216.1 1040135 D 204722 CDS NP_700217.1 23500777 1165501 1040956..1041402 1 NC_004311.2 similar to GP:15155425; identified by sequence similarity; universal stress protein 1041402 1165501 BRA1055 Brucella suis 1330 universal stress protein NP_700217.1 1040956 D 204722 CDS NP_700218.1 23500778 1165502 complement(1041519..1041737) 1 NC_004311.2 hypothetical protein 1041737 1165502 BRA1056 Brucella suis 1330 hypothetical protein NP_700218.1 1041519 R 204722 CDS NP_700219.1 23500779 1165503 1041891..1042322 1 NC_004311.2 hypothetical protein 1042322 1165503 BRA1057 Brucella suis 1330 hypothetical protein NP_700219.1 1041891 D 204722 CDS NP_700220.1 23500780 1165504 1042324..1043724 1 NC_004311.2 similar to GP:3336914; identified by sequence similarity; aldehyde dehydrogenase 1043724 1165504 BRA1058 Brucella suis 1330 aldehyde dehydrogenase NP_700220.1 1042324 D 204722 CDS NP_700221.1 23500781 1165505 1043879..1044736 1 NC_004311.2 similar to GP:15074185, and GP:15074185; identified by sequence similarity; hypothetical protein 1044736 1165505 BRA1059 Brucella suis 1330 hypothetical protein NP_700221.1 1043879 D 204722 CDS NP_700222.1 23500782 1165506 complement(1044746..1046206) 1 NC_004311.2 similar to GP:15157671, and SP:O66043; identified by sequence similarity; cardiolipin synthase 1046206 cls 1165506 cls Brucella suis 1330 cardiolipin synthase NP_700222.1 1044746 R 204722 CDS NP_700223.1 23500783 1165507 1046378..1046941 1 NC_004311.2 hypothetical protein 1046941 1165507 BRA1061 Brucella suis 1330 hypothetical protein NP_700223.1 1046378 D 204722 CDS NP_700224.1 23500784 1165508 complement(1046953..1047066) 1 NC_004311.2 hypothetical protein 1047066 1165508 BRA1062 Brucella suis 1330 hypothetical protein NP_700224.1 1046953 R 204722 CDS NP_700225.1 23500785 1165509 1047102..1048679 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01393; peptide chain release factor 3 1048679 prfC 1165509 prfC Brucella suis 1330 peptide chain release factor 3 NP_700225.1 1047102 D 204722 CDS NP_700226.1 23500786 1165510 complement(1048676..1049896) 1 NC_004311.2 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase 1049896 coaBC 1165510 coaBC Brucella suis 1330 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase NP_700226.1 1048676 R 204722 CDS NP_700227.1 23500787 1165511 complement(1049927..1051510) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00069; ubiquinone biosynthesis protein UbiB 1051510 ubiB 1165511 ubiB Brucella suis 1330 ubiquinone biosynthesis protein UbiB NP_700227.1 1049927 R 204722 CDS NP_700228.1 23500788 1165512 complement(1051559..1052368) 1 NC_004311.2 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase 1052368 ubiE 1165512 ubiE Brucella suis 1330 ubiquinone/menaquinone biosynthesis methyltransferase NP_700228.1 1051559 R 204722 CDS NP_700229.2 161486703 1165513 1052679..1053305 1 NC_004311.2 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1053305 upp 1165513 upp Brucella suis 1330 uracil phosphoribosyltransferase NP_700229.2 1052679 D 204722 CDS NP_700230.2 161486702 1165514 1053416..1053622 1 NC_004311.2 identified by match to PFAM protein family HMM PF03670; hypothetical protein 1053622 1165514 BRA1068 Brucella suis 1330 hypothetical protein NP_700230.2 1053416 D 204722 CDS NP_700231.1 23500791 1165515 complement(1053635..1054291) 1 NC_004311.2 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A 1054291 msrA 1165515 msrA Brucella suis 1330 methionine sulfoxide reductase A NP_700231.1 1053635 R 204722 CDS NP_700232.1 23500792 1165516 complement(1054314..1054637) 1 NC_004311.2 hypothetical protein 1054637 1165516 BRA1070 Brucella suis 1330 hypothetical protein NP_700232.1 1054314 R 204722 CDS NP_700233.1 23500793 1165517 complement(1054615..1054767) 1 NC_004311.2 hypothetical protein 1054767 1165517 BRA1071 Brucella suis 1330 hypothetical protein NP_700233.1 1054615 R 204722 CDS NP_700234.1 23500794 1165519 complement(1055309..1056217) 1 NC_004311.2 similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; IS3 family transposase orfB 1056217 1165519 BRA1072 Brucella suis 1330 IS3 family transposase orfB NP_700234.1 1055309 R 204722 CDS NP_700235.1 23500795 1165520 complement(1056214..1056495) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA 1056495 1165520 BRA1073 Brucella suis 1330 IS3 family transposase orfA NP_700235.1 1056214 R 204722 CDS NP_700236.1 23500796 1165521 1056737..1057468 1 NC_004311.2 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1057468 1165521 BRA1074 Brucella suis 1330 GntR family transcriptional regulator NP_700236.1 1056737 D 204722 CDS NP_700237.1 23500797 1165522 1057465..1057593 1 NC_004311.2 hypothetical protein 1057593 1165522 BRA1075 Brucella suis 1330 hypothetical protein NP_700237.1 1057465 D 204722 CDS NP_700238.1 23500798 1165523 complement(1057664..1059106) 1 NC_004311.2 similar to GP:15159844; identified by sequence similarity; aldehyde dehydrogenase 1059106 1165523 BRA1076 Brucella suis 1330 aldehyde dehydrogenase NP_700238.1 1057664 R 204722 CDS NP_700239.1 23500799 1165524 complement(1059118..1060380) 1 NC_004311.2 similar to GP:14587414; identified by sequence similarity; CAIB/BAIF family protein 1060380 1165524 BRA1077 Brucella suis 1330 CAIB/BAIF family protein NP_700239.1 1059118 R 204722 CDS NP_700240.1 23500800 1165525 complement(1060436..1061440) 1 NC_004311.2 similar to GP:3402247; identified by sequence similarity; peptide ABC transporter ATP-binding protein 1061440 1165525 BRA1078 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_700240.1 1060436 R 204722 CDS NP_700241.1 23500801 1165526 complement(1061433..1062470) 1 NC_004311.2 similar to GB:M23592, GB:M23593, GB:M23594, GB:M23595, GB:M20841, GB:M74587, GB:M59316, GB:M31145, GB:X12385, GB:X15002, GB:X13405, GB:Y00856, SP:P08833, PID:183118, PID:184810, PID:184812, PID:184826, PID:32609, PID:33014, PID:35572, and PID:35575; identified by sequence similarity; peptide ABC transporter ATP-binding protein 1062470 1165526 BRA1079 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_700241.1 1061433 R 204722 CDS NP_700242.1 23500802 1165527 complement(1062483..1063328) 1 NC_004311.2 similar to SP:P94312; identified by sequence similarity; peptide ABC transporter permease 1063328 1165527 BRA1080 Brucella suis 1330 peptide ABC transporter permease NP_700242.1 1062483 R 204722 CDS NP_700243.1 23500803 1165528 complement(1063340..1064353) 1 NC_004311.2 similar to SP:P94311; identified by sequence similarity; peptide ABC transporter permease 1064353 1165528 BRA1081 Brucella suis 1330 peptide ABC transporter permease NP_700243.1 1063340 R 204722 CDS NP_700244.1 23500804 1165529 1064529..1065335 1 NC_004311.2 identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator 1065335 1165529 BRA1082 Brucella suis 1330 IclR family transcriptional regulator NP_700244.1 1064529 D 204722 CDS NP_700245.1 23500805 1165531 complement(1066765..1068384) 1 NC_004311.2 similar to GB:L17071, SP:Q07608, GB:U23753, PID:310304, and PID:763542; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein 1068384 1165531 BRA1084 Brucella suis 1330 ABC transporter periplasmic substrate-binding protein NP_700245.1 1066765 R 204722 CDS NP_700246.1 23500806 1165533 complement(1070601..1072106) 1 NC_004311.2 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 1072106 1165533 BRA1086 Brucella suis 1330 3-hydroxyacyl-CoA dehydrogenase NP_700246.1 1070601 R 204722 CDS NP_700247.1 23500807 1165534 complement(1072123..1072905) 1 NC_004311.2 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 1072905 1165534 BRA1087 Brucella suis 1330 enoyl-CoA hydratase NP_700247.1 1072123 R 204722 CDS NP_700248.1 23500808 1165535 1073088..1074230 1 NC_004311.2 similar to SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase 1074230 1165535 BRA1088 Brucella suis 1330 acyl-CoA dehydrogenase NP_700248.1 1073088 D 204722 CDS NP_700249.1 23500809 1165536 1074556..1076841 1 NC_004311.2 similar to SP:P15558; identified by sequence similarity; penicillin amidase 1076841 1165536 BRA1089 Brucella suis 1330 penicillin amidase NP_700249.1 1074556 D 204722 CDS NP_700250.1 23500810 1165537 1076864..1078408 1 NC_004311.2 similar to GP:15160115, and SP:P55669; identified by sequence similarity; peptide ABC transporter substrate-binding protein 1078408 1165537 BRA1090 Brucella suis 1330 peptide ABC transporter substrate-binding protein NP_700250.1 1076864 D 204722 CDS NP_700251.1 23500811 1165538 complement(1078458..1078553) 1 NC_004311.2 hypothetical protein 1078553 1165538 BRA1091 Brucella suis 1330 hypothetical protein NP_700251.1 1078458 R 204722 CDS NP_700252.1 23500812 1165539 1078565..1079509 1 NC_004311.2 similar to GP:10172641, and GP:18092570; identified by sequence similarity; peptide ABC transporter permease 1079509 1165539 BRA1092 Brucella suis 1330 peptide ABC transporter permease NP_700252.1 1078565 D 204722 CDS NP_700253.1 23500813 1165540 1079502..1080392 1 NC_004311.2 similar to GP:15160117, and SP:P94312; identified by sequence similarity; peptide ABC transporter permease 1080392 1165540 BRA1093 Brucella suis 1330 peptide ABC transporter permease NP_700253.1 1079502 D 204722 CDS NP_700254.1 23500814 1165541 1080395..1081393 1 NC_004311.2 similar to GP:15158781; identified by sequence similarity; peptide ABC transporter ATP-binding protein 1081393 1165541 BRA1094 Brucella suis 1330 peptide ABC transporter ATP-binding protein NP_700254.1 1080395 D 204722 CDS NP_700255.1 23500815 1165543 1082617..1083330 1 NC_004311.2 similar to GP:14523620; identified by sequence similarity; transcriptional regulator 1083330 1165543 BRA1096 Brucella suis 1330 transcriptional regulator NP_700255.1 1082617 D 204722 CDS NP_700256.1 23500816 1165544 1083396..1084952 1 NC_004311.2 similar to GP:18092565; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1084952 1165544 BRA1097 Brucella suis 1330 oligopeptide ABC transporter periplasmic oligopeptide-binding protein NP_700256.1 1083396 D 204722 CDS NP_700257.1 23500817 1165545 1084988..1085998 1 NC_004311.2 similar to SP:P94311; identified by sequence similarity; peptide ABC transporter permease 1085998 1165545 BRA1098 Brucella suis 1330 peptide ABC transporter permease NP_700257.1 1084988 D 204722 CDS NP_700258.1 23500818 1165546 1085995..1086828 1 NC_004311.2 similar to SP:P94312; identified by sequence similarity; peptide ABC transporter permease 1086828 1165546 BRA1099 Brucella suis 1330 peptide ABC transporter permease NP_700258.1 1085995 D 204722 CDS NP_700259.1 23500819 1165548 1087816..1088793 1 NC_004311.2 similar to SP:Q53194, GB:M62834, SP:P24093, GB:X69102, PID:145801, PID:433881, PID:639970, and SP:Q57254; identified by sequence similarity; oligopeptide ABC transporter ATP-binding protein 1088793 1165548 BRA1101 Brucella suis 1330 oligopeptide ABC transporter ATP-binding protein NP_700259.1 1087816 D 204722 CDS NP_700260.1 23500820 1165549 1088793..1089665 1 NC_004311.2 similar to GB:M20867, GB:M18377, GB:J03248, GB:M17697, GB:M37154, GB:X07769, GB:X53146, GB:X66300, SP:P00367, SP:P49448, PID:1335082, PID:183054, PID:183056, PID:183058, PID:183060, PID:183062, PID:31707, PID:31799, PID:478988, and PID:579924; identified by sequence similarity; gluconolactonase 1089665 1165549 BRA1102 Brucella suis 1330 gluconolactonase NP_700260.1 1088793 D 204722 CDS NP_700261.1 23500821 1165550 1089680..1091098 1 NC_004311.2 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1091098 1165550 BRA1103 Brucella suis 1330 amidase NP_700261.1 1089680 D 204722 CDS NP_700262.1 23500822 1165552 complement(1092218..1093021) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00969; polyamine ABC transporter permease 1093021 1165552 BRA1105 Brucella suis 1330 polyamine ABC transporter permease NP_700262.1 1092218 R 204722 CDS NP_700263.1 23500823 1165553 complement(1093018..1093833) 1 NC_004311.2 similar to SP:P23860, GB:L26967, SP:P12780, PID:152249, and PID:435107; identified by sequence similarity; polyamine ABC transporter permease 1093833 1165553 BRA1106 Brucella suis 1330 polyamine ABC transporter permease NP_700263.1 1093018 R 204722 CDS NP_700264.1 23500824 1165555 1095294..1096499 1 NC_004311.2 identified by match to PFAM protein family HMM PF03781; glutamate-1-semialdehyde 2,1-aminomutase 1096499 1165555 BRA1108 Brucella suis 1330 glutamate-1-semialdehyde 2,1-aminomutase NP_700264.1 1095294 D 204722 CDS NP_700265.1 23500825 1165556 1096649..1098328 1 NC_004311.2 hypothetical protein 1098328 1165556 BRA1109 Brucella suis 1330 hypothetical protein NP_700265.1 1096649 D 204722 CDS NP_700266.1 23500826 1165557 1098524..1099183 1 NC_004311.2 similar to GP:15075256, GB:X12466, GB:M37716, GB:M15919, SP:P08578, PID:338267, PID:338269, and PID:35105; identified by sequence similarity; L-fuculose phosphate aldolase 1099183 1165557 BRA1110 Brucella suis 1330 L-fuculose phosphate aldolase NP_700266.1 1098524 D 204722 CDS NP_700267.1 23500827 1165558 1099278..1100537 1 NC_004311.2 similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, PID:386807, GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; hypothetical protein 1100537 1165558 BRA1111 Brucella suis 1330 hypothetical protein NP_700267.1 1099278 D 204722 CDS NP_700268.1 23500828 1165559 1100515..1101027 1 NC_004311.2 hypothetical protein 1101027 1165559 BRA1112 Brucella suis 1330 hypothetical protein NP_700268.1 1100515 D 204722 CDS NP_700269.1 23500829 1165560 complement(1101036..1101320) 1 NC_004311.2 identified by match to PFAM protein family HMM PF02452; pemK family protein 1101320 1165560 BRA1113 Brucella suis 1330 pemK family protein NP_700269.1 1101036 R 204722 CDS NP_700270.1 23500830 1165562 1102687..1102968 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA 1102968 1165562 BRA1115 Brucella suis 1330 IS3 family transposase orfA NP_700270.1 1102687 D 204722 CDS NP_700271.1 23500831 1165563 1102965..1103846 1 NC_004311.2 similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; IS3 family transposase orfB 1103846 1165563 BRA1116 Brucella suis 1330 IS3 family transposase orfB NP_700271.1 1102965 D 204722 CDS NP_700272.1 23500832 1165570 complement(1109574..1109699) 1 NC_004311.2 hypothetical protein 1109699 1165570 BRA1117 Brucella suis 1330 hypothetical protein NP_700272.1 1109574 R 204722 CDS NP_700273.1 23500833 1165571 1110339..1111205 1 NC_004311.2 similar to GP:14024748, and GP:14024748; identified by sequence similarity; hypothetical protein 1111205 1165571 BRA1118 Brucella suis 1330 hypothetical protein NP_700273.1 1110339 D 204722 CDS NP_700274.1 23500834 1165572 1111521..1111916 1 NC_004311.2 identified by match to PFAM protein family HMM PF02082; RrF2 family protein 1111916 1165572 BRA1119 Brucella suis 1330 RrF2 family protein NP_700274.1 1111521 D 204722 CDS NP_700275.1 23500835 1165573 complement(1111977..1113179) 1 NC_004311.2 similar to GP:15160214; identified by sequence similarity; cobalamin synthesis protein/P47K family protein 1113179 1165573 BRA1120 Brucella suis 1330 cobalamin synthesis protein/P47K family protein NP_700275.1 1111977 R 204722 CDS NP_700276.1 23500836 1165574 1113204..1113344 1 NC_004311.2 hypothetical protein 1113344 1165574 BRA1121 Brucella suis 1330 hypothetical protein NP_700276.1 1113204 D 204722 CDS NP_700277.1 23500837 1165575 complement(1113346..1114350) 1 NC_004311.2 similar to GP:15074849, and SP:P39172; identified by sequence similarity; zinc ABC transporter periplasmic zinc-binding protein 1114350 znuA 1165575 znuA Brucella suis 1330 zinc ABC transporter periplasmic zinc-binding protein NP_700277.1 1113346 R 204722 CDS NP_700278.1 23500838 1165576 1114577..1115473 1 NC_004311.2 similar to GP:15156606; identified by sequence similarity; zinc ABC transporter ATP-binding protein 1115473 znuC 1165576 znuC Brucella suis 1330 zinc ABC transporter ATP-binding protein NP_700278.1 1114577 D 204722 CDS NP_700279.1 23500839 1165577 1115427..1116287 1 NC_004311.2 similar to GP:15074847, and GP:17739944; identified by sequence similarity; zinc ABC transporter permease 1116287 znuB 1165577 znuB Brucella suis 1330 zinc ABC transporter permease NP_700279.1 1115427 D 204722 CDS NP_700280.1 23500840 1165578 1116284..1116721 1 NC_004311.2 similar to GP:15156604; identified by sequence similarity; FUR family transcriptional regulator 1116721 1165578 BRA1125 Brucella suis 1330 FUR family transcriptional regulator NP_700280.1 1116284 D 204722 CDS NP_700281.1 23500841 1165579 1116848..1117183 1 NC_004311.2 hypothetical protein 1117183 1165579 BRA1126 Brucella suis 1330 hypothetical protein NP_700281.1 1116848 D 204722 CDS NP_700282.1 23500842 1165580 complement(1117171..1117698) 1 NC_004311.2 hypothetical protein 1117698 1165580 BRA1127 Brucella suis 1330 hypothetical protein NP_700282.1 1117171 R 204722 CDS NP_700283.1 23500843 1165581 complement(1117695..1118171) 1 NC_004311.2 similar to GP:15073620; identified by sequence similarity; hypothetical protein 1118171 1165581 BRA1128 Brucella suis 1330 hypothetical protein NP_700283.1 1117695 R 204722 CDS NP_700284.1 23500844 1165582 complement(1118312..1118902) 1 NC_004311.2 similar to GP:15073619, and GP:15073619; identified by sequence similarity; hypothetical protein 1118902 1165582 BRA1129 Brucella suis 1330 hypothetical protein NP_700284.1 1118312 R 204722 CDS NP_700285.1 23500845 1165583 complement(1118970..1119377) 1 NC_004311.2 similar to GP:3876134; identified by sequence similarity; hypothetical protein 1119377 1165583 BRA1130 Brucella suis 1330 hypothetical protein NP_700285.1 1118970 R 204722 CDS NP_700286.1 23500846 1165584 complement(1119385..1120152) 1 NC_004311.2 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR 1120152 fliR 1165584 fliR Brucella suis 1330 flagellar biosynthesis protein FliR NP_700286.1 1119385 R 204722 CDS NP_700287.1 23500847 1165585 complement(1120168..1122339) 1 NC_004311.2 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1122339 flhA 1165585 flhA Brucella suis 1330 flagellar biosynthesis protein FlhA NP_700287.1 1120168 R 204722 CDS NP_700288.1 23500848 1165586 complement(1122419..1122685) 1 NC_004311.2 FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ 1122685 fliQ 1165586 fliQ Brucella suis 1330 flagellar biosynthesis protein FliQ NP_700288.1 1122419 R 204722 CDS NP_700289.1 23500849 1165587 complement(1122697..1123110) 1 NC_004311.2 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein 1123110 flgD 1165587 flgD Brucella suis 1330 flagellar basal body rod modification protein NP_700289.1 1122697 R 204722 CDS NP_700290.1 23500850 1165588 complement(1123107..1123565) 1 NC_004311.2 post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT 1123565 flbT 1165588 flbT Brucella suis 1330 flagellar biosynthesis repressor FlbT NP_700290.1 1123107 R 204722 CDS NP_700291.1 23500851 1165589 complement(1123567..1123911) 1 NC_004311.2 acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF 1123911 flaF 1165589 flaF Brucella suis 1330 flagellar biosynthesis regulatory protein FlaF NP_700291.1 1123567 R 204722 CDS NP_700292.1 23500852 1165590 complement(1124043..1125089) 1 NC_004311.2 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL 1125089 flgL 1165590 flgL Brucella suis 1330 flagellar hook-associated protein FlgL NP_700292.1 1124043 R 204722 CDS NP_700293.1 23500853 1165591 complement(1125095..1126549) 1 NC_004311.2 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK 1126549 flgK 1165591 flgK Brucella suis 1330 flagellar hook-associated protein FlgK NP_700293.1 1125095 R 204722 CDS NP_700294.1 23500854 1165592 complement(1126674..1127864) 1 NC_004311.2 the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE 1127864 flgE 1165592 flgE Brucella suis 1330 flagellar hook protein FlgE NP_700294.1 1126674 R 204722 CDS NP_700295.1 23500855 1165593 complement(1128275..1128958) 1 NC_004311.2 similar to GP:15073608; identified by sequence similarity; transcriptional regulator 1128958 1165593 BRA1140 Brucella suis 1330 transcriptional regulator NP_700295.1 1128275 R 204722 CDS NP_700296.1 23500856 1165594 complement(1129286..1129858) 1 NC_004311.2 similar to GP:15073607, and GP:15073607; identified by sequence similarity; hypothetical protein 1129858 1165594 BRA1141 Brucella suis 1330 hypothetical protein NP_700296.1 1129286 R 204722 CDS NP_700297.1 23500857 1165595 complement(1129812..1131074) 1 NC_004311.2 similar to GP:15155510, and SP:Q52964; identified by sequence similarity; motD-like protein 1131074 1165595 BRA1142 Brucella suis 1330 motD-like protein NP_700297.1 1129812 R 204722 CDS NP_700298.1 23500858 1165597 complement(1132372..1133472) 1 NC_004311.2 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB 1133472 motB 1165597 motB Brucella suis 1330 flagellar motor protein MotB NP_700298.1 1132372 R 204722 CDS NP_700299.1 23500859 1165598 complement(1133469..1134149) 1 NC_004311.2 similar to GP:15155507, and GP:12057223; identified by sequence similarity; hypothetical protein 1134149 1165598 BRA1145 Brucella suis 1330 hypothetical protein NP_700299.1 1133469 R 204722 CDS NP_700300.1 23500860 1165599 complement(1134152..1135894) 1 NC_004311.2 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 1135894 fliF 1165599 fliF Brucella suis 1330 flagellar MS-ring protein NP_700300.1 1134152 R 204722 CDS NP_700301.1 23500861 1165600 complement(1136107..1136955) 1 NC_004311.2 similar to GP:2832232; identified by sequence similarity; flagellin family protein 1136955 1165600 BRA1147 Brucella suis 1330 flagellin family protein NP_700301.1 1136107 R 204722 CDS NP_700302.1 23500862 1165601 1137593..1147855 1 NC_004311.2 similar to GP:15162141, and GP:15162141; identified by sequence similarity; outer membrane autotransporter 1147855 1165601 BRA1148 Brucella suis 1330 outer membrane autotransporter NP_700302.1 1137593 D 204722 CDS NP_700303.1 23500863 1165602 complement(1147972..1149027) 1 NC_004311.2 hypothetical protein 1149027 1165602 BRA1149 Brucella suis 1330 hypothetical protein NP_700303.1 1147972 R 204722 CDS NP_700304.1 23500864 1165603 1149601..1150620 1 NC_004311.2 similar to GB:X03656, GB:X03438, GB:M17706, SP:P09919, PID:1330309, PID:1330310, PID:183041, PID:183045, PID:296647, PID:31690, and PID:732764; identified by sequence similarity; D-xylose ABC transporter periplasmic D-xylose-binding protein 1150620 xylF 1165603 xylF Brucella suis 1330 D-xylose ABC transporter periplasmic D-xylose-binding protein NP_700304.1 1149601 D 204722 CDS NP_700305.1 23500865 1165604 1150782..1152317 1 NC_004311.2 with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 1152317 xylG 1165604 xylG Brucella suis 1330 xylose transporter ATP-binding subunit NP_700305.1 1150782 D 204722 CDS NP_700306.1 23500866 1165605 1152460..1153629 1 NC_004311.2 similar to GB:L17326, and PID:306325; identified by sequence similarity; D-xylose ABC transporter permease 1153629 xylH 1165605 xylH Brucella suis 1330 D-xylose ABC transporter permease NP_700306.1 1152460 D 204722 CDS NP_700307.1 23500867 1165606 1153673..1153876 1 NC_004311.2 hypothetical protein 1153876 1165606 BRA1153 Brucella suis 1330 hypothetical protein NP_700307.1 1153673 D 204722 CDS NP_700308.1 23500868 1165607 1154187..1155155 1 NC_004311.2 similar to SP:P36673, GB:U07790, PID:465107, PID:537083, GB:U00096, PID:1790689, and PID:1843456; identified by sequence similarity; AraC family transcriptional regulator 1155155 1165607 BRA1154 Brucella suis 1330 AraC family transcriptional regulator NP_700308.1 1154187 D 204722 CDS NP_700309.1 23500869 1165608 1155255..1156661 1 NC_004311.2 similar to GP:4566586; identified by sequence similarity; aldehyde dehydrogenase 1156661 1165608 BRA1155 Brucella suis 1330 aldehyde dehydrogenase NP_700309.1 1155255 D 204722 CDS NP_700310.1 23500870 1165609 complement(1156818..1157627) 1 NC_004311.2 similar to GB:M79446, SP:P24182, GB:M83198, PID:145175, PID:145893, PID:145896, PID:606196, GB:U00096, PID:1789654, GB:U03272, SP:P35556, and PID:437972; identified by sequence similarity; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 1157627 1165609 BRA1156 Brucella suis 1330 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase NP_700310.1 1156818 R 204722 CDS NP_700311.1 23500871 1165610 complement(1157694..1157804) 1 NC_004311.2 hypothetical protein 1157804 1165610 BRA1157 Brucella suis 1330 hypothetical protein NP_700311.1 1157694 R 204722 CDS NP_700312.1 23500872 1165611 complement(1157845..1158648) 1 NC_004311.2 similar to GB:M98276, SP:Q04626, GB:M64046, PID:151020, PID:45360, SP:P77915, PID:1515308, GB:M13300, GB:M13301, GB:M13302, GB:M13303, GB:M13304, GB:M13305, GB:X54705, GB:X54675, GB:Z68193, SP:P04000, SP:P04001, PID:1122284, and PID:180703; identified by sequence similarity; 2-keto-4-pentenoate hydratase 1158648 hpaH 1165611 hpaH Brucella suis 1330 2-keto-4-pentenoate hydratase NP_700312.1 1157845 R 204722 CDS NP_700313.1 23500873 1165612 complement(1158652..1159518) 1 NC_004311.2 similar to GP:14424793; identified by sequence similarity; fumarylacetoacetate hydrolase 1159518 1165612 BRA1159 Brucella suis 1330 fumarylacetoacetate hydrolase NP_700313.1 1158652 R 204722 CDS NP_700314.1 23500874 1165614 complement(1160622..1162136) 1 NC_004311.2 similar to GB:X75771, and PID:455422; identified by sequence similarity; 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase 1162136 1165614 BRA1161 Brucella suis 1330 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase NP_700314.1 1160622 R 204722 CDS NP_700315.1 23500875 1165615 complement(1162206..1162598) 1 NC_004311.2 similar to GP:10048282, and SP:Q05354; identified by sequence similarity; 5-carboxymethyl-2-hydroxymuconate delta-isomerase 1162598 hpcD 1165615 hpcD Brucella suis 1330 5-carboxymethyl-2-hydroxymuconate delta-isomerase NP_700315.1 1162206 R 204722 CDS NP_700316.1 23500876 1165616 1162764..1163255 1 NC_004311.2 identified by match to PFAM protein family HMM PF03551; MarR family transcriptional regulator 1163255 1165616 BRA1163 Brucella suis 1330 MarR family transcriptional regulator NP_700316.1 1162764 D 204722 CDS NP_700317.1 23500877 1165617 complement(1163245..1164264) 1 NC_004311.2 similar to GP:15162021, and GP:14026357; identified by sequence similarity; hypothetical protein 1164264 1165617 BRA1164 Brucella suis 1330 hypothetical protein NP_700317.1 1163245 R 204722 CDS NP_700318.1 23500878 1165618 complement(1164242..1165525) 1 NC_004311.2 similar to GP:14524116; identified by sequence similarity; aminotransferase 1165525 1165618 BRA1165 Brucella suis 1330 aminotransferase NP_700318.1 1164242 R 204722 CDS NP_700319.1 23500879 1165619 complement(1165527..1166885) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00699; hypothetical protein 1166885 1165619 BRA1166 Brucella suis 1330 hypothetical protein NP_700319.1 1165527 R 204722 CDS NP_700320.1 23500880 1165620 complement(1166898..1167542) 1 NC_004311.2 similar to GB:M60787, and PID:150163; identified by sequence similarity; HAD superfamily hydrolase 1167542 1165620 BRA1167 Brucella suis 1330 HAD superfamily hydrolase NP_700320.1 1166898 R 204722 CDS NP_700321.1 23500881 1165621 complement(1167539..1168795) 1 NC_004311.2 similar to GP:14271863; identified by sequence similarity; hypothetical protein 1168795 1165621 BRA1168 Brucella suis 1330 hypothetical protein NP_700321.1 1167539 R 204722 CDS NP_700322.1 23500882 1165622 complement(1168795..1169577) 1 NC_004311.2 similar to GB:D12765, SP:P43268, PID:219611, and PID:602288; identified by sequence similarity; IclR family transcriptional regulator 1169577 1165622 BRA1169 Brucella suis 1330 IclR family transcriptional regulator NP_700322.1 1168795 R 204722 CDS NP_700323.1 23500883 1165623 1169827..1171320 1 NC_004311.2 similar to GP:5441757; identified by sequence similarity; amino acid permease 1171320 1165623 BRA1170 Brucella suis 1330 amino acid permease NP_700323.1 1169827 D 204722 CDS NP_700324.1 23500884 1165624 1171392..1172870 1 NC_004311.2 similar to GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; aldehyde dehydrogenase 1172870 1165624 BRA1171 Brucella suis 1330 aldehyde dehydrogenase NP_700324.1 1171392 D 204722 CDS NP_700325.1 23500885 1165625 1173029..1174711 1 NC_004311.2 hypothetical protein 1174711 1165625 BRA1172 Brucella suis 1330 hypothetical protein NP_700325.1 1173029 D 204722 CDS NP_700326.1 23500886 1165626 1174778..1175959 1 NC_004311.2 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1175959 1165626 BRA1173 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_700326.1 1174778 D 204722 CDS NP_700327.1 23500887 1165627 1176032..1176901 1 NC_004311.2 similar to GP:9716222; identified by sequence similarity; branched-chain amino acid ABC transporter permease 1176901 1165627 BRA1174 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_700327.1 1176032 D 204722 CDS NP_700328.1 23500888 1165628 1176888..1178600 1 NC_004311.2 similar to GP:15156481; identified by sequence similarity; branched chain amino acid ABC transporter ATP-binding/permease 1178600 1165628 BRA1175 Brucella suis 1330 branched chain amino acid ABC transporter ATP-binding/permease NP_700328.1 1176888 D 204722 CDS NP_700329.1 23500889 1165629 1178597..1179301 1 NC_004311.2 similar to GB:M16442, and PID:143790; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1179301 1165629 BRA1176 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_700329.1 1178597 D 204722 CDS NP_700330.1 23500890 1165630 complement(1179396..1179719) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03988; hypothetical protein 1179719 1165630 BRA1177 Brucella suis 1330 hypothetical protein NP_700330.1 1179396 R 204722 CDS NP_700331.1 23500891 1165631 complement(1179734..1180603) 1 NC_004311.2 identified by match to PFAM protein family HMM PF03741; hypothetical protein 1180603 1165631 BRA1178 Brucella suis 1330 hypothetical protein NP_700331.1 1179734 R 204722 CDS NP_700332.1 23500892 1165632 complement(1180609..1181343) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1181343 1165632 BRA1179 Brucella suis 1330 GntR family transcriptional regulator NP_700332.1 1180609 R 204722 CDS NP_700333.1 23500893 1165633 complement(1181488..1182753) 1 NC_004311.2 sugar ABC transporter periplasmic sugar-binding protein 1182753 1165633 BRA1180 Brucella suis 1330 sugar ABC transporter periplasmic sugar-binding protein NP_700333.1 1181488 R 204722 CDS NP_700334.1 23500894 1165634 complement(1182788..1183609) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00023; sugar ABC transporter permease 1183609 1165634 BRA1181 Brucella suis 1330 sugar ABC transporter permease NP_700334.1 1182788 R 204722 CDS NP_700335.1 23500895 1165635 complement(1183620..1184579) 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter permease 1184579 1165635 BRA1182 Brucella suis 1330 sugar ABC transporter permease NP_700335.1 1183620 R 204722 CDS NP_700336.1 23500896 1165636 complement(1184545..1185723) 1 NC_004311.2 similar to SP:Q01937; identified by sequence similarity; sugar ABC transporter ATP-binding protein 1185723 1165636 BRA1183 Brucella suis 1330 sugar ABC transporter ATP-binding protein NP_700336.1 1184545 R 204722 CDS NP_700337.1 23500897 1165637 complement(1185720..1186565) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00149; purple acid phosphatase 1186565 1165637 BRA1184 Brucella suis 1330 purple acid phosphatase NP_700337.1 1185720 R 204722 CDS NP_700338.1 23500898 1165638 complement(1186840..1188327) 1 NC_004311.2 identified by match to PFAM protein family HMM PF00884; sulfatase 1188327 1165638 BRA1185 Brucella suis 1330 sulfatase NP_700338.1 1186840 R 204722 CDS NP_700339.1 23500899 1165639 complement(1188470..1189429) 1 NC_004311.2 similar to GP:7799282, and SP:Q47537; identified by sequence similarity; taurine ABC transporter taurine-binding protein 1189429 1165639 BRA1186 Brucella suis 1330 taurine ABC transporter taurine-binding protein NP_700339.1 1188470 R 204722 CDS NP_700340.1 23500900 1165640 complement(1189445..1190227) 1 NC_004311.2 similar to GP:7799281; identified by sequence similarity; taurine ABC transporter ATP-binding protein 1190227 1165640 BRA1187 Brucella suis 1330 taurine ABC transporter ATP-binding protein NP_700340.1 1189445 R 204722 CDS NP_700341.1 23500901 1165641 complement(1190224..1190976) 1 NC_004311.2 similar to GP:7799280, and SP:Q47539; identified by sequence similarity; taurine ABC transporter permease 1190976 1165641 BRA1188 Brucella suis 1330 taurine ABC transporter permease NP_700341.1 1190224 R 204722 CDS NP_700342.1 23500902 1165642 complement(1190973..1192097) 1 NC_004311.2 similar to GP:2661680; identified by sequence similarity; ROK family protein 1192097 1165642 BRA1189 Brucella suis 1330 ROK family protein NP_700342.1 1190973 R 204722 CDS NP_700343.1 23500903 1165643 complement(1192353..1194338) 1 NC_004311.2 similar to GB:X73376, GB:X73377, GB:X73378, GB:X73379, GB:X73380, GB:X73381, GB:X73382, GB:X73384, GB:X73385, PID:475179, and PID:475185; identified by sequence similarity; TonB dependent receptor domain-containing protein 1194338 1165643 BRA1190 Brucella suis 1330 TonB dependent receptor domain-containing protein NP_700343.1 1192353 R 204722 CDS NP_700344.1 23500904 1165644 complement(1194335..1194457) 1 NC_004311.2 hypothetical protein 1194457 1165644 BRA1191 Brucella suis 1330 hypothetical protein NP_700344.1 1194335 R 204722 CDS NP_700345.1 23500905 1165645 1194806..1195585 1 NC_004311.2 identified by match to PFAM protein family HMM PF00191; AraC family transcriptional regulator 1195585 1165645 BRA1192 Brucella suis 1330 AraC family transcriptional regulator NP_700345.1 1194806 D 204722 CDS NP_700346.1 23500906 1165646 1195735..1196955 1 NC_004311.2 similar to GP:151110, and SP:P04816; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1196955 1165646 BRA1193 Brucella suis 1330 branched-chain amino acid ABC transporter periplasmic amino acid-binding protein NP_700346.1 1195735 D 204722 CDS NP_700347.1 23500907 1165647 1197157..1198020 1 NC_004311.2 similar to GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter permease 1198020 1165647 BRA1194 Brucella suis 1330 branched-chain amino acid ABC transporter permease NP_700347.1 1197157 D 204722 CDS NP_700348.1 23500908 1165649 1198961..1199695 1 NC_004311.2 similar to GB:M59757, SP:P25993, PID:143389, and GB:AL009126; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1199695 1165649 BRA1196 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_700348.1 1198961 D 204722 CDS NP_700349.1 23500909 1165650 1199692..1200420 1 NC_004311.2 similar to SP:P22731, GB:M16442, and PID:143790; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1200420 1165650 BRA1197 Brucella suis 1330 branched-chain amino acid ABC transporter ATP-binding protein NP_700349.1 1199692 D 204722 CDS NP_700350.1 23500910 1165651 complement(1200449..1202389) 1 NC_004311.2 similar to GP:3128316, and GP:17984226; identified by sequence similarity; cadmium-translocating P-type ATPase 1202389 cadA-2 1165651 cadA-2 Brucella suis 1330 cadmium-translocating P-type ATPase NP_700350.1 1200449 R 204722 CDS NP_700351.1 23500911 1165652 complement(1202669..1204021) 1 NC_004311.2 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 1204021 hemN-2 1165652 hemN-2 Brucella suis 1330 coproporphyrinogen III oxidase NP_700351.1 1202669 R 204722 CDS NP_700352.1 23500912 1165653 complement(1204114..1204338) 1 NC_004311.2 hypothetical protein 1204338 1165653 BRA1200 Brucella suis 1330 hypothetical protein NP_700352.1 1204114 R 204722 CDS NP_700353.1 23500913 1165654 complement(1204305..1204709) 1 NC_004311.2 hypothetical protein 1204709 1165654 BRA1201 Brucella suis 1330 hypothetical protein NP_700353.1 1204305 R 204722 CDS NP_700354.1 23500914 1165655 1204923..1206116 1 NC_004311.2 identified by match to TIGR protein family HMM TIGR01281; replication protein RepA 1206116 repA 1165655 repA Brucella suis 1330 replication protein RepA NP_700354.1 1204923 D 204722 CDS NP_700355.1 23500915 1165656 1206181..1207167 1 NC_004311.2 similar to SP:P55392; identified by sequence similarity; replication protein RepB 1207167 1165656 BRA1203 Brucella suis 1330 replication protein RepB NP_700355.1 1206181 D 204722 CDS