-- dump date 20140619_011536 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 204722000001 SEQ_END SEQ_END NC_004310.3 2107794 2107794 DR NC_004310.3; contig end 2107794..2107794 Brucella suis 1330 204722000002 SEQ_END SEQ_END NC_004311.2 1207381 1207381 DR NC_004311.2; contig end 1207381..1207381 Brucella suis 1330 NP_697044.1 CDS dnaA NC_004310.3 784 2274 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 784..2274 Brucella suis 1330 1165657 NP_697045.1 CDS dnaN NC_004310.3 2503 3696 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 2503..3696 Brucella suis 1330 1165658 NP_697046.1 CDS recF NC_004310.3 3878 5032 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 3878..5032 Brucella suis 1330 1165659 NP_697047.1 CDS moeB NC_004310.3 5070 5852 D ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase; molybdopterin biosynthesis protein MoeB 5070..5852 Brucella suis 1330 1165660 NP_697048.1 CDS BR0005 NC_004310.3 5869 6825 R identified by similarity to EGAD:90750; match to protein family HMM PF02826; D-isomer specific 2-hydroxyacid dehydrogenase complement(5869..6825) Brucella suis 1330 1165661 NP_697049.1 CDS BR0006 NC_004310.3 6822 8447 R identified by similarity to SP:P33916; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(6822..8447) Brucella suis 1330 1165662 NP_697050.1 CDS BR0007 NC_004310.3 8471 9610 R identified by similarity to GP:17983985; match to protein family HMM PF00528; ABC transporter permease complement(8471..9610) Brucella suis 1330 1165663 NP_697051.1 CDS BR0008 NC_004310.3 9610 10707 R identified by similarity to SP:P33914; match to protein family HMM PF00528; ABC transporter permease complement(9610..10707) Brucella suis 1330 1165664 NP_697052.1 CDS BR0009 NC_004310.3 10819 12633 R identified by similarity to SP:P33913; match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein complement(10819..12633) Brucella suis 1330 1165665 NP_697053.1 CDS BR0010 NC_004310.3 12680 14548 R identified by match to protein family HMM PF00496; ABC transporter periplasmic substrate-binding protein complement(12680..14548) Brucella suis 1330 1165666 NP_697054.1 CDS BR0011 NC_004310.3 14779 15102 R hypothetical protein complement(14779..15102) Brucella suis 1330 1165667 NP_697055.1 CDS BR0012 NC_004310.3 15148 15348 R hypothetical protein complement(15148..15348) Brucella suis 1330 1165668 NP_697056.1 CDS BR0013 NC_004310.3 15388 15738 R hypothetical protein complement(15388..15738) Brucella suis 1330 1165669 NP_697057.1 CDS BR0014 NC_004310.3 16003 17109 R identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter perisplasmic amino acid-binding protein complement(16003..17109) Brucella suis 1330 1165670 NP_697058.1 CDS BR0015 NC_004310.3 17381 17581 D identified by similarity to OMNI:NTL02ML1891; hypothetical protein 17381..17581 Brucella suis 1330 1165671 NP_697059.1 CDS BR0016 NC_004310.3 17578 18372 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(17578..18372) Brucella suis 1330 1165672 NP_697060.1 CDS BR0018 NC_004310.3 19224 21245 R identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; biotin carboxylase complement(19224..21245) Brucella suis 1330 1165674 NP_697061.1 CDS BR0019 NC_004310.3 21257 22864 R identified by match to protein family HMM PF01039; carboxyl transferase complement(21257..22864) Brucella suis 1330 1165675 NP_697062.1 CDS ivd NC_004310.3 22864 24012 R identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; isovaleryl-CoA dehydrogenase complement(22864..24012) Brucella suis 1330 1165676 NP_697063.1 CDS BR0021 NC_004310.3 24189 26177 R AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; acetoacetyl-CoA synthetase complement(24189..26177) Brucella suis 1330 1165677 NP_697064.1 CDS BR0022 NC_004310.3 26362 26796 R identified by similarity to OMNI:NTL02ML1269; hypothetical protein complement(26362..26796) Brucella suis 1330 1165678 NP_697065.1 CDS BR0023 NC_004310.3 26973 28094 R identified by similarity to OMNI:CC1521; match to protein family HMM PF01757; hypothetical protein complement(26973..28094) Brucella suis 1330 1165679 NP_697066.1 CDS BR0024 NC_004310.3 28617 29000 R identified by similarity to GP:15073181; hypothetical protein complement(28617..29000) Brucella suis 1330 1165681 NP_697067.1 CDS aroA NC_004310.3 29385 30737 D catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 29385..30737 Brucella suis 1330 1165682 NP_697068.1 CDS cmk NC_004310.3 30734 31393 D Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 30734..31393 Brucella suis 1330 1165683 NP_697069.1 CDS rpsA NC_004310.3 31609 33309 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 31609..33309 Brucella suis 1330 1165684 NP_697070.1 CDS BR0028 NC_004310.3 33727 34737 R identified by similarity to GP:15155628; match to protein family HMM PF03601; hypothetical protein complement(33727..34737) Brucella suis 1330 1165685 NP_697071.1 CDS BR0029 NC_004310.3 34853 35752 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 34853..35752 Brucella suis 1330 1165686 NP_697072.1 CDS BR0030 NC_004310.3 35746 36321 R hypothetical protein complement(35746..36321) Brucella suis 1330 1165687 NP_697073.1 CDS BR0031 NC_004310.3 36357 37640 R transglycosylase complement(36357..37640) Brucella suis 1330 1165688 NP_697074.1 CDS recR NC_004310.3 37656 38261 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(37656..38261) Brucella suis 1330 1165689 NP_697075.1 CDS BR0033 NC_004310.3 38392 38715 R identified by similarity to OMNI:NTL02ML4268; match to protein family HMM PF02575; match to protein family HMM TIGR00103; hypothetical protein complement(38392..38715) Brucella suis 1330 1165690 NP_697076.1 CDS dnaX NC_004310.3 38740 40548 R catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau complement(38740..40548) Brucella suis 1330 1165691 NP_697077.1 CDS BR0035 NC_004310.3 40829 41233 D identified by similarity to OMNI:NTL02ML4266; match to protein family HMM PF01230; hypothetical protein 40829..41233 Brucella suis 1330 1165692 NP_697078.1 CDS BR0036 NC_004310.3 41262 42209 D identified by similarity to OMNI:NTL02ML4265; match to protein family HMM PF00293; MutT/nudix family protein 41262..42209 Brucella suis 1330 1165693 NP_697079.1 CDS pheA NC_004310.3 42210 43073 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(42210..43073) Brucella suis 1330 1165694 NP_697080.1 CDS kdsB NC_004310.3 43162 43917 R CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS; 3-deoxy-manno-octulosonate cytidylyltransferase complement(43162..43917) Brucella suis 1330 1165695 NP_697081.1 CDS BR0039 NC_004310.3 44295 44903 D identified by similarity to EGAD:14195; match to protein family HMM PF00034; cytochrome c, membrane-bound 44295..44903 Brucella suis 1330 1165696 NP_697082.1 CDS BR0040 NC_004310.3 44948 45913 R identified by similarity to GP:14021137; match to protein family HMM PF00994; hypothetical protein complement(44948..45913) Brucella suis 1330 1165697 NP_697083.1 CDS BR0041 NC_004310.3 45969 46277 D hypothetical protein 45969..46277 Brucella suis 1330 1165698 NP_697084.1 CDS cyoA NC_004310.3 46440 47465 D identified by similarity to EGAD:20044; match to protein family HMM TIGR01433; ubiquinol oxidase subunit II 46440..47465 Brucella suis 1330 1165699 NP_697085.1 CDS qoxB NC_004310.3 47545 49524 D identified by similarity to EGAD:14783; match to protein family HMM PF00115; ubiquinol oxidase subunit I 47545..49524 Brucella suis 1330 1165700 NP_697086.1 CDS BR0044 NC_004310.3 49528 50157 D identified by similarity to EGAD:13682; match to protein family HMM PF00510; ubiquinol oxidase subunit III 49528..50157 Brucella suis 1330 1165701 NP_697087.1 CDS qoxD NC_004310.3 50157 50522 D identified by similarity to EGAD:20825; match to protein family HMM PF03626; ubiquinol oxidase subunit IV 50157..50522 Brucella suis 1330 1165702 NP_697088.1 CDS BR0046 NC_004310.3 50519 50797 R hypothetical protein complement(50519..50797) Brucella suis 1330 1165703 NP_697089.1 CDS BR0047 NC_004310.3 50973 51560 D identified by similarity to GP:3511221; hypothetical protein 50973..51560 Brucella suis 1330 1165704 NP_697090.1 CDS BR0048 NC_004310.3 52156 54075 D identified by similarity to OMNI:NTL02ML1304; match to protein family HMM PF01103; hypothetical protein 52156..54075 Brucella suis 1330 1165705 NP_697091.1 CDS BR0049 NC_004310.3 54264 58811 D identified by similarity to GP:15076022; match to protein family HMM PF04357; match to protein family HMM TIGR01612; hypothetical protein 54264..58811 Brucella suis 1330 1165706 NP_697092.1 CDS BR0050 NC_004310.3 58956 59681 D identified by similarity to GP:15160041; match to protein family HMM PF03734; match to protein family HMM TIGR01409; lipoprotein 58956..59681 Brucella suis 1330 1165707 NP_697093.1 CDS BR0051 NC_004310.3 59732 59947 R hypothetical protein complement(59732..59947) Brucella suis 1330 1165708 NP_697094.1 CDS BR0052 NC_004310.3 60017 60520 R hypothetical protein complement(60017..60520) Brucella suis 1330 1165709 NP_697095.1 CDS BR0053 NC_004310.3 60857 61063 R hypothetical protein complement(60857..61063) Brucella suis 1330 1165710 NP_697096.1 CDS BR0054 NC_004310.3 61074 62078 R identified by similarity to GP:15074483; match to protein family HMM PF04314; hypothetical protein complement(61074..62078) Brucella suis 1330 1165711 NP_697097.1 CDS BR0055 NC_004310.3 62213 62611 R hypothetical protein complement(62213..62611) Brucella suis 1330 1165712 NP_697098.1 CDS BR0056 NC_004310.3 62864 63259 R identified by match to protein family HMM PF00903; glyoxalase complement(62864..63259) Brucella suis 1330 1165713 NP_697099.1 CDS BR0057 NC_004310.3 63456 64619 D identified by match to protein family HMM PF01883; mrp-like protein 63456..64619 Brucella suis 1330 1165714 NP_697100.1 CDS pgm NC_004310.3 64824 66455 R catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; phosphoglucomutase complement(64824..66455) Brucella suis 1330 1165715 NP_697101.1 CDS BR0059 NC_004310.3 66511 66696 R hypothetical protein complement(66511..66696) Brucella suis 1330 1165716 NP_697102.1 CDS BR0060 NC_004310.3 66671 67564 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(66671..67564) Brucella suis 1330 1165717 NP_697103.1 CDS BR0061 NC_004310.3 67689 68612 D dienelactone hydrolase domain-containing protein 67689..68612 Brucella suis 1330 1165718 NP_697104.1 CDS frcK NC_004310.3 68685 69383 D identified by similarity to GP:11066210; fructose transport system kinase 68685..69383 Brucella suis 1330 1165719 NP_697105.1 CDS BR0063 NC_004310.3 69483 70172 D identified by match to protein family HMM PF01557; fumarylacetoacetate hydrolase 69483..70172 Brucella suis 1330 1165720 NP_697106.1 CDS BR0064 NC_004310.3 70192 70383 D identified by similarity to GP:15073555; hypothetical protein 70192..70383 Brucella suis 1330 1165721 NP_697107.1 CDS BR0065 NC_004310.3 70445 70660 D hypothetical protein 70445..70660 Brucella suis 1330 1165722 NP_697108.1 CDS BR0066 NC_004310.3 70826 71014 D identified by similarity to OMNI:NTL02ML3554; hypothetical protein 70826..71014 Brucella suis 1330 1165723 NP_697109.1 CDS BR0067 NC_004310.3 71029 71892 D identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein 71029..71892 Brucella suis 1330 1165724 NP_697110.1 CDS BR0068 NC_004310.3 72078 72734 D identified by similarity to EGAD:38000; match to protein family HMM PF03006; hemolysin III family channel protein 72078..72734 Brucella suis 1330 1165725 NP_697111.1 CDS dnaE2 NC_004310.3 72875 76108 R DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase.; error-prone DNA polymerase complement(72875..76108) Brucella suis 1330 1165726 NP_697112.1 CDS BR0070 NC_004310.3 76108 77559 R identified by similarity to GP:14523587; hypothetical protein complement(76108..77559) Brucella suis 1330 1165727 NP_697113.1 CDS BR0071 NC_004310.3 77585 78448 R identified by similarity to GP:15076199; hypothetical protein complement(77585..78448) Brucella suis 1330 1165728 NP_697114.1 CDS BR0072 NC_004310.3 78967 81189 D identified by similarity to SP:P10858; match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662; hypothetical protein 78967..81189 Brucella suis 1330 1165729 NP_697115.1 CDS BR0073 NC_004310.3 81398 81946 D identified by similarity to GP:15073388; hypothetical protein 81398..81946 Brucella suis 1330 1165730 NP_697116.1 CDS argG NC_004310.3 82025 83245 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(82025..83245) Brucella suis 1330 1165731 NP_697117.1 CDS BR0076 NC_004310.3 84095 84598 R hypothetical protein complement(84095..84598) Brucella suis 1330 1165733 NP_697118.1 CDS BR0077 NC_004310.3 84632 85867 R identified by similarity to OMNI:NTL02ML3355; match to protein family HMM PF04055; match to protein family HMM TIGR00048; hypothetical protein complement(84632..85867) Brucella suis 1330 1165734 NP_697119.1 CDS BR0078 NC_004310.3 85811 86002 D hypothetical protein 85811..86002 Brucella suis 1330 1165735 NP_697120.1 CDS BR0079 NC_004310.3 85987 86181 D hypothetical protein 85987..86181 Brucella suis 1330 1165736 NP_697121.1 CDS BR0080 NC_004310.3 86127 86630 R identified by similarity to GP:15076241; hypothetical protein complement(86127..86630) Brucella suis 1330 1165737 NP_697122.1 CDS BR0081 NC_004310.3 87070 87453 R identified by similarity to GP:15076242; hypothetical protein complement(87070..87453) Brucella suis 1330 1165738 NP_697123.1 CDS phhB NC_004310.3 87541 87834 R 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction; pterin-4-alpha-carbinolamine dehydratase complement(87541..87834) Brucella suis 1330 1165739 NP_697124.1 CDS BR0083 NC_004310.3 88061 88666 D identified by match to protein family HMM PF01451; phosphotyrosine protein phosphatase 88061..88666 Brucella suis 1330 1165740 NP_697125.1 CDS BR0084 NC_004310.3 88576 89166 R identified by similarity to OMNI:NTL02ML3347; hypothetical protein complement(88576..89166) Brucella suis 1330 1165741 NP_697126.1 CDS BR0085 NC_004310.3 89347 90072 R identified by match to protein family HMM PF00657; lipase/acylhydrolase domain-containing protein complement(89347..90072) Brucella suis 1330 1165742 NP_697127.1 CDS BR0086 NC_004310.3 90219 90947 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 90219..90947 Brucella suis 1330 1165743 NP_697128.1 CDS BR0087 NC_004310.3 90944 93493 D identified by match to protein family HMM PF02687; ABC transporter permease 90944..93493 Brucella suis 1330 1165744 NP_697129.1 CDS BR0088 NC_004310.3 93727 94464 D identified by similarity to GP:15076248; match to protein family HMM PF01027; hypothetical protein 93727..94464 Brucella suis 1330 1165745 NP_697130.1 CDS pat NC_004310.3 94579 95118 D identified by similarity to EGAD:8993; match to protein family HMM PF00583; phosphinothricin N-acetyltransferase 94579..95118 Brucella suis 1330 1165746 NP_697131.1 CDS BR0090 NC_004310.3 95138 95539 R identified by similarity to GP:15076253; hypothetical protein complement(95138..95539) Brucella suis 1330 1165747 NP_697132.1 CDS BR0091 NC_004310.3 96089 96823 R identified by similarity to GP:15076254; hypothetical protein complement(96089..96823) Brucella suis 1330 1165748 NP_697133.1 CDS BR0092 NC_004310.3 96976 97116 R hypothetical protein complement(96976..97116) Brucella suis 1330 1165749 NP_697134.1 CDS acnA NC_004310.3 97100 99787 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(97100..99787) Brucella suis 1330 1165750 NP_697135.1 CDS ccmA NC_004310.3 100131 100778 D ATP-binding protein; required for proper cytochrome c maturation; cytochrome c biogenesis protein CcmA 100131..100778 Brucella suis 1330 1165751 NP_697136.1 CDS ccmB NC_004310.3 100778 101443 D identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190; heme exporter protein CcmB 100778..101443 Brucella suis 1330 1165752 NP_697137.1 CDS ccmC NC_004310.3 101501 102286 D identified by similarity to SP:P30962; match to protein family HMM PF01578; match to protein family HMM TIGR01191; heme exporter protein CcmC 101501..102286 Brucella suis 1330 1165753 NP_697138.1 CDS BR0097 NC_004310.3 102283 102456 D identified by similarity to EGAD:15659; match to protein family HMM PF04995; heme exporter protein D 102283..102456 Brucella suis 1330 1165754 NP_697139.1 CDS cycY NC_004310.3 102453 103064 D identified by match to protein family HMM TIGR00385; thioredoxin 102453..103064 Brucella suis 1330 1165755 NP_697140.1 CDS ilvD NC_004310.3 103313 105148 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(103313..105148) Brucella suis 1330 1165756 NP_697141.1 CDS BR0100 NC_004310.3 105330 105467 D hypothetical protein 105330..105467 Brucella suis 1330 1165757 NP_697142.1 CDS BR0101 NC_004310.3 105548 105901 R identified by similarity to GP:15157523; hypothetical protein complement(105548..105901) Brucella suis 1330 1165758 NP_697143.1 CDS BR0102 NC_004310.3 106006 106383 R identified by similarity to OMNI:CC3015; match to protein family HMM PF00072; response regulator complement(106006..106383) Brucella suis 1330 1165759 NP_697144.1 CDS BR0103 NC_004310.3 106558 106794 R transcriptional regulator complement(106558..106794) Brucella suis 1330 1165760 NP_697145.1 CDS BR0104 NC_004310.3 107447 107851 D identified by similarity to GP:15155891; hypothetical protein 107447..107851 Brucella suis 1330 1165761 NP_697146.1 CDS BR0105 NC_004310.3 107937 108641 R hypothetical protein complement(107937..108641) Brucella suis 1330 1165762 NP_697147.1 CDS BR0106 NC_004310.3 108713 109531 D identified by similarity to EGAD:8060; hypothetical protein 108713..109531 Brucella suis 1330 1165763 NP_697148.1 CDS BR0107 NC_004310.3 109809 110837 D identified by similarity to GP:17983880; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter sulfate-binding protein 109809..110837 Brucella suis 1330 1165764 NP_697149.1 CDS BR0108 NC_004310.3 110932 111798 D identified by similarity to SP:Q01895; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease 110932..111798 Brucella suis 1330 1165765 NP_697150.1 CDS cysW-1 NC_004310.3 111788 112654 D identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease 111788..112654 Brucella suis 1330 1165766 NP_697151.1 CDS BR0110 NC_004310.3 112752 113831 D identified by similarity to SP:P14788; match to protein family HMM PF00005; match to protein family HMM TIGR00968; sulfate ABC transporter ATP-binding protein 112752..113831 Brucella suis 1330 1165767 NP_697152.1 CDS BR0111 NC_004310.3 114622 122820 D identified by similarity to GP:3551791; match to protein family HMM TIGR01612; cyclic beta 1-2 glucan synthetase 114622..122820 Brucella suis 1330 1165768 NP_697153.1 CDS pncB NC_004310.3 122910 124214 D catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 122910..124214 Brucella suis 1330 1165769 NP_697154.1 CDS BR0113 NC_004310.3 124256 125086 R identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein complement(124256..125086) Brucella suis 1330 1165770 NP_697155.1 CDS BR0114 NC_004310.3 125196 125984 R identified by similarity to GP:15075131; hypothetical protein complement(125196..125984) Brucella suis 1330 1165771 NP_697156.1 CDS cscK NC_004310.3 126007 126933 R identified by similarity to EGAD:15614; match to protein family HMM PF00294; fructokinase complement(126007..126933) Brucella suis 1330 1165772 NP_697157.1 CDS BR0116 NC_004310.3 127024 127830 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase complement(127024..127830) Brucella suis 1330 1165773 NP_697158.1 CDS BR0117 NC_004310.3 127951 130242 R identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein complement(127951..130242) Brucella suis 1330 1165774 NP_697159.1 CDS BR0118 NC_004310.3 130447 131139 R hypothetical protein complement(130447..131139) Brucella suis 1330 1165775 NP_697160.1 CDS BR0119 NC_004310.3 131407 132093 R identified by similarity to EGAD:151783; hypothetical protein complement(131407..132093) Brucella suis 1330 1165776 NP_697161.1 CDS BR0120 NC_004310.3 132325 132942 R identified by match to protein family HMM PF01612; 3'-5' exonuclease complement(132325..132942) Brucella suis 1330 1165777 NP_697162.1 CDS BR0121 NC_004310.3 132981 134396 R identified by match to protein family HMM PF01546; hypothetical protein complement(132981..134396) Brucella suis 1330 1165778 NP_697163.1 CDS BR0122 NC_004310.3 134549 134875 D hypothetical protein 134549..134875 Brucella suis 1330 1165779 NP_697164.1 CDS polA NC_004310.3 134957 137896 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 134957..137896 Brucella suis 1330 1165780 NP_697165.1 CDS BR0124 NC_004310.3 138038 139918 D identified by similarity to SP:P23304; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; DEAD-box ATP dependent DNA helicase 138038..139918 Brucella suis 1330 1165781 NP_697166.1 CDS gyrB NC_004310.3 140014 142446 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B complement(140014..142446) Brucella suis 1330 1165782 NP_697167.1 CDS BR0126 NC_004310.3 142506 142673 R hypothetical protein complement(142506..142673) Brucella suis 1330 1165783 NP_697168.1 CDS BR0127 NC_004310.3 142777 143532 R identified by similarity to OMNI:NTL02ML5595; match to protein family HMM PF00756; esterase complement(142777..143532) Brucella suis 1330 1165784 NP_697169.1 CDS BR0128 NC_004310.3 143621 144277 R identified by similarity to GP:14021760; hypothetical protein complement(143621..144277) Brucella suis 1330 1165785 NP_697170.1 CDS BR0129 NC_004310.3 144277 144744 R identified by match to protein family HMM PF00583; acetyltransferase complement(144277..144744) Brucella suis 1330 1165786 NP_697171.1 CDS BR0131 NC_004310.3 145890 146174 R identified by similarity to EGAD:97446; match to protein family HMM PF02583; hypothetical protein complement(145890..146174) Brucella suis 1330 1165788 NP_697172.1 CDS BR0133 NC_004310.3 148850 150142 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 148850..150142 Brucella suis 1330 1165790 NP_697173.1 CDS BR0134 NC_004310.3 150234 150545 D identified by similarity to EGAD:46813; IS711, transposase orfA 150234..150545 Brucella suis 1330 1165791 NP_697174.1 CDS BR0135 NC_004310.3 150577 150969 D identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 150577..150969 Brucella suis 1330 1165792 NP_697175.1 CDS BR0136 NC_004310.3 151035 151373 D hypothetical protein 151035..151373 Brucella suis 1330 1165793 NP_697176.1 CDS BR0137 NC_004310.3 151569 152132 D identified by match to protein family HMM PF00072; match to protein family HMM TIGR01199; DNA-binding response regulator 151569..152132 Brucella suis 1330 1165794 NP_697177.1 CDS BR0138 NC_004310.3 152138 152632 R identified by similarity to GP:15154914; hypothetical protein complement(152138..152632) Brucella suis 1330 1165795 NP_697178.1 CDS BR0139 NC_004310.3 152901 153521 D identified by similarity to GP:9392598; match to protein family HMM PF03734; lipoprotein 152901..153521 Brucella suis 1330 1165796 NP_697179.1 CDS BR0140 NC_004310.3 153611 154183 R identified by match to protein family HMM PF01106; NifU-like protein complement(153611..154183) Brucella suis 1330 1165797 NP_697180.1 CDS BR0141 NC_004310.3 154292 154780 R identified by similarity to GP:15155260; match to protein family HMM PF00582; hypothetical protein complement(154292..154780) Brucella suis 1330 1165798 NP_697181.2 CDS trpS NC_004310.3 154838 155905 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase complement(154838..155905) Brucella suis 1330 1165799 NP_697182.1 CDS mviN NC_004310.3 156002 157591 R identified by similarity to SP:P56882; match to protein family HMM PF03023; match to protein family HMM TIGR01695; virulence factor MviN complement(156002..157591) Brucella suis 1330 1165800 NP_697183.1 CDS BR0144 NC_004310.3 157605 160409 R catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein; PII uridylyl-transferase complement(157605..160409) Brucella suis 1330 1165801 NP_697184.1 CDS BR0145 NC_004310.3 160475 160570 D hypothetical protein 160475..160570 Brucella suis 1330 1165802 NP_697185.1 CDS mutS NC_004310.3 162981 165713 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 162981..165713 Brucella suis 1330 1165804 NP_697186.1 CDS BR0148 NC_004310.3 166019 166864 R identified by similarity to GP:15073322; hypothetical protein complement(166019..166864) Brucella suis 1330 1165805 NP_697187.1 CDS lspA NC_004310.3 167187 167669 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(167187..167669) Brucella suis 1330 1165806 NP_697188.1 CDS BR0150 NC_004310.3 167671 168564 R identified by match to protein family HMM PF00588; RNA methyltransferase complement(167671..168564) Brucella suis 1330 1165807 NP_697189.1 CDS BR0151 NC_004310.3 168561 169706 R identified by similarity to OMNI:NTL02ML2473; SAM dependent methyltransferase complement(168561..169706) Brucella suis 1330 1165808 NP_697190.1 CDS BR0152 NC_004310.3 169819 170142 R identified by similarity to GP:15073316; hypothetical protein complement(169819..170142) Brucella suis 1330 1165809 NP_697191.1 CDS ihfB NC_004310.3 170152 170436 R This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta complement(170152..170436) Brucella suis 1330 1165810 NP_697192.1 CDS sppA NC_004310.3 170483 171478 R identified by match to protein family HMM PF01343; match to protein family HMM TIGR00706; signal peptide peptidase SppA complement(170483..171478) Brucella suis 1330 1165811 NP_697193.1 CDS BR0155 NC_004310.3 171997 172650 D identified by similarity to GP:15155241; hypothetical protein 171997..172650 Brucella suis 1330 1165812 NP_697194.1 CDS BR0156 NC_004310.3 172973 173587 D identified by similarity to GP:15155240; match to protein family HMM PF03968; hypothetical protein 172973..173587 Brucella suis 1330 1165813 NP_697195.1 CDS BR0157 NC_004310.3 173599 174432 D identified by similarity to GP:17983823; match to protein family HMM PF00005; ABC transporter ATP-binding protein 173599..174432 Brucella suis 1330 1165814 NP_697196.1 CDS rpoN NC_004310.3 174728 176230 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen; RNA polymerase factor sigma-54 174728..176230 Brucella suis 1330 1165815 NP_697197.1 CDS BR0159 NC_004310.3 176379 176744 R hypothetical protein complement(176379..176744) Brucella suis 1330 1165816 NP_697198.1 CDS yfiA NC_004310.3 176980 177573 D identified by match to protein family HMM PF02482; match to protein family HMM TIGR00741; ribosomal subunit interface protein 176980..177573 Brucella suis 1330 1165817 NP_697199.1 CDS ptsN NC_004310.3 177676 178140 D identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419; PTS system, nitrogen regulatory IIA component 177676..178140 Brucella suis 1330 1165818 NP_697200.1 CDS BR0162 NC_004310.3 178221 178466 R identified by similarity to GP:15073342; hypothetical protein complement(178221..178466) Brucella suis 1330 1165819 NP_697201.1 CDS BR0163 NC_004310.3 178572 179054 R identified by similarity to OMNI:CC3592; match to protein family HMM PF00011; heat shock protein 20 complement(178572..179054) Brucella suis 1330 1165820 NP_697202.1 CDS BR0164 NC_004310.3 179085 179297 R hypothetical protein complement(179085..179297) Brucella suis 1330 1165821 NP_697203.1 CDS BR0165 NC_004310.3 179266 179763 R identified by similarity to GP:15158767; hypothetical protein complement(179266..179763) Brucella suis 1330 1165822 NP_697204.1 CDS nth NC_004310.3 179868 180614 D identified by similarity to EGAD:18451; match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01083; endonuclease III 179868..180614 Brucella suis 1330 1165823 NP_697205.1 CDS BR0167 NC_004310.3 180655 181368 R role in sulfur assimilation; CysZ-like protein complement(180655..181368) Brucella suis 1330 1165824 NP_697206.1 CDS BR0168 NC_004310.3 181365 181625 R hypothetical protein complement(181365..181625) Brucella suis 1330 1165825 NP_697207.1 CDS BR0169 NC_004310.3 181628 182620 D identified by match to protein family HMM PF00294; carbohydrate kinase 181628..182620 Brucella suis 1330 1165826 NP_697208.1 CDS BR0170 NC_004310.3 182639 183295 R identified by similarity to GP:15155036; match to protein family HMM PF03458; hypothetical protein complement(182639..183295) Brucella suis 1330 1165827 NP_697209.1 CDS grpE NC_004310.3 183428 184120 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(183428..184120) Brucella suis 1330 1165828 NP_697210.1 CDS hrcA NC_004310.3 184226 185350 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor complement(184226..185350) Brucella suis 1330 1165829 NP_697211.1 CDS rph NC_004310.3 185518 186234 D RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 185518..186234 Brucella suis 1330 1165830 NP_697212.1 CDS BR0174 NC_004310.3 186408 186812 D identified by match to protein family HMM PF00903; glyoxalase 186408..186812 Brucella suis 1330 1165831 NP_697213.1 CDS BR0175 NC_004310.3 186815 187477 D HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase 186815..187477 Brucella suis 1330 1165832 NP_697214.1 CDS BR0176 NC_004310.3 187531 188688 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 187531..188688 Brucella suis 1330 1165833 NP_697215.1 CDS BR0177 NC_004310.3 188754 189611 D identified by similarity to OMNI:CC0144; match to protein family HMM PF00590; match to protein family HMM TIGR00096; tetrapyrrole methylase 188754..189611 Brucella suis 1330 1165834 NP_697216.1 CDS BR0178 NC_004310.3 189608 189988 D identified by similarity to GP:15073266; match to protein family HMM PF02021; hypothetical protein 189608..189988 Brucella suis 1330 1165835 NP_697217.1 CDS cysG NC_004310.3 190208 191641 D identified by similarity to SP:P11098; match to protein family HMM PF00590; match to protein family HMM TIGR01469; match to protein family HMM TIGR01470; siroheme synthase 190208..191641 Brucella suis 1330 1165836 NP_697218.1 CDS BR0180 NC_004310.3 191659 191961 D identified by similarity to GP:15156533; hypothetical protein 191659..191961 Brucella suis 1330 1165837 NP_697219.1 CDS cysI NC_004310.3 191982 193652 D identified by similarity to OMNI:CC1119; match to protein family HMM PF01077; match to protein family HMM PF03460; sulfite reductase (NADPH) hemoprotein subunit beta 191982..193652 Brucella suis 1330 1165838 NP_697220.1 CDS cysH NC_004310.3 193642 194400 D catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 193642..194400 Brucella suis 1330 1165839 NP_697221.1 CDS BR0183 NC_004310.3 194453 194977 D identified by similarity to GP:15156535; hypothetical protein 194453..194977 Brucella suis 1330 1165840 NP_697222.1 CDS BR0184 NC_004310.3 195045 195338 D identified by similarity to GP:14021352; hypothetical protein 195045..195338 Brucella suis 1330 1165841 NP_697223.1 CDS ogt NC_004310.3 195339 195917 R identified by similarity to OMNI:CC0659; match to protein family HMM PF01035; match to protein family HMM TIGR00589; methylated-DNA--protein-cysteine methyltransferase complement(195339..195917) Brucella suis 1330 1165842 NP_697224.1 CDS BR0186 NC_004310.3 196175 196420 D identified by similarity to GP:14025509; hypothetical protein 196175..196420 Brucella suis 1330 1165843 NP_697225.1 CDS BR0187 NC_004310.3 196473 196862 R identified by similarity to GP:15073804; hypothetical protein complement(196473..196862) Brucella suis 1330 1165844 NP_697226.1 CDS metH NC_004310.3 197176 200961 D one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity; B12-dependent methionine synthase 197176..200961 Brucella suis 1330 1165845 NP_697227.1 CDS BR0189 NC_004310.3 200925 201092 R hypothetical protein complement(200925..201092) Brucella suis 1330 1165846 NP_697228.1 CDS BR0190 NC_004310.3 201282 201989 D identified by match to protein family HMM PF00196; match to protein family HMM PF03472; LuxR family transcriptional regulator 201282..201989 Brucella suis 1330 1165847 NP_697229.1 CDS BR0191 NC_004310.3 202104 203474 D identified by match to protein family HMM PF00202; aminotransferase 202104..203474 Brucella suis 1330 1165848 NP_697230.1 CDS BR0192 NC_004310.3 203514 203699 R hypothetical protein complement(203514..203699) Brucella suis 1330 1165849 NP_697231.1 CDS cysD NC_004310.3 203878 204780 D with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 203878..204780 Brucella suis 1330 1165850 NP_697232.1 CDS cysNC NC_004310.3 204780 206714 D in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis; bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase 204780..206714 Brucella suis 1330 1165851 NP_697233.1 CDS cysQ NC_004310.3 206762 207562 D identified by similarity to SP:P22255; match to protein family HMM PF00459; match to protein family HMM TIGR01331; 3'(2'),5'-bisphosphate nucleotidase 206762..207562 Brucella suis 1330 1165852 NP_697234.1 CDS BR0196 NC_004310.3 207824 208585 R identified by match to protein family HMM PF00027; Crp/Fnr family transcriptional regulator complement(207824..208585) Brucella suis 1330 1165854 NP_697235.1 CDS BR0198 NC_004310.3 209538 209669 D hypothetical protein 209538..209669 Brucella suis 1330 1165856 NP_697236.1 CDS glpR NC_004310.3 209891 210682 D identified by similarity to SP:P09392; match to protein family HMM PF00455; glycerol-3-phosphate transcriptional regulator 209891..210682 Brucella suis 1330 1165857 NP_697237.1 CDS glpD NC_004310.3 210764 212275 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 210764..212275 Brucella suis 1330 1165858 NP_697238.1 CDS BR0202 NC_004310.3 213612 215129 D identified by match to protein family HMM PF00171; aldehyde dehydrogenase 213612..215129 Brucella suis 1330 1165860 NP_697239.1 CDS BR0203 NC_004310.3 215610 216644 D identified by similarity to SP:P42327; match to protein family HMM PF00107; alcohol dehydrogenase 215610..216644 Brucella suis 1330 1165861 NP_697240.1 CDS BR0204 NC_004310.3 216735 217067 D identified by similarity to OMNI:NTL02ML5214; match to protein family HMM PF05610; hypothetical protein 216735..217067 Brucella suis 1330 1165862 NP_697241.1 CDS BR0207 NC_004310.3 219596 220165 D hypothetical protein 219596..220165 Brucella suis 1330 1165865 NP_697242.1 CDS BR0208 NC_004310.3 220207 220305 R hypothetical protein complement(220207..220305) Brucella suis 1330 1165866 NP_697243.1 CDS BR0209 NC_004310.3 220300 220455 D hypothetical protein 220300..220455 Brucella suis 1330 1165867 NP_697244.1 CDS BR0210 NC_004310.3 220468 221901 D identified by similarity to EGAD:17385; match to protein family HMM PF00171; aldehyde dehydrogenase 220468..221901 Brucella suis 1330 1165868 NP_697245.1 CDS BR0211 NC_004310.3 221946 222722 R identified by match to protein family HMM PF00528; ABC transporter permease complement(221946..222722) Brucella suis 1330 1165869 NP_697246.1 CDS BR0212 NC_004310.3 222719 223417 R identified by similarity to EGAD:24145; match to protein family HMM PF03070; transcriptional regulator TenA complement(222719..223417) Brucella suis 1330 1165870 NP_697247.1 CDS BR0213 NC_004310.3 223414 224382 R ABC transporter periplasmic substrate-binding protein complement(223414..224382) Brucella suis 1330 1165871 NP_697248.1 CDS thiE NC_004310.3 224406 225017 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase complement(224406..225017) Brucella suis 1330 1165872 NP_697249.1 CDS thiG NC_004310.3 225014 225784 R functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase complement(225014..225784) Brucella suis 1330 1165873 NP_697250.1 CDS BR0216 NC_004310.3 225786 225983 R identified by similarity to SP:O32583; match to protein family HMM PF02597; match to protein family HMM TIGR01683; thiamine biosynthesis protein ThiS complement(225786..225983) Brucella suis 1330 1165874 NP_697251.1 CDS BR0217 NC_004310.3 225980 226984 R identified by match to protein family HMM PF01266; D-amino acid oxidase complement(225980..226984) Brucella suis 1330 1165875 NP_697252.1 CDS thiD NC_004310.3 226984 227859 R identified by match to protein family HMM TIGR00097; phosphomethylpyrimidine kinase complement(226984..227859) Brucella suis 1330 1165876 NP_697253.1 CDS BR0219 NC_004310.3 228288 230399 D identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein 228288..230399 Brucella suis 1330 1165877 NP_697254.1 CDS BR0220 NC_004310.3 230498 232978 D identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR00003; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; copper-translocating P-type ATPase 230498..232978 Brucella suis 1330 1165878 NP_697255.1 CDS BR0221 NC_004310.3 232958 233407 R identified by match to protein family HMM PF00376; MerR family transcriptional regulator complement(232958..233407) Brucella suis 1330 1165879 NP_697256.1 CDS BR0222 NC_004310.3 233513 234259 R identified by match to protein family HMM PF00528; ABC transporter permease complement(233513..234259) Brucella suis 1330 1165880 NP_697257.1 CDS BR0223 NC_004310.3 234256 235194 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(234256..235194) Brucella suis 1330 1165881 NP_697258.1 CDS BR0224 NC_004310.3 235191 236351 R identified by similarity to SP:P33361; match to protein family HMM PF00528; ABC transporter permease complement(235191..236351) Brucella suis 1330 1165882 NP_697259.1 CDS BR0225 NC_004310.3 236424 237338 R identified by similarity to GP:17983752; match to protein family HMM PF04069; ABC transporter periplasmic substrate-binding protein complement(236424..237338) Brucella suis 1330 1165883 NP_697260.1 CDS BR0226 NC_004310.3 237524 238189 R identified by similarity to OMNI:NTL02ML0782; hypothetical protein complement(237524..238189) Brucella suis 1330 1165884 NP_697261.1 CDS BR0227 NC_004310.3 238479 239744 R identified by similarity to EGAD:22862; match to protein family HMM PF00208; match to protein family HMM PF02812; glutamate dehydrogenase complement(238479..239744) Brucella suis 1330 1165885 NP_697262.1 CDS BR0228 NC_004310.3 239935 240102 D hypothetical protein 239935..240102 Brucella suis 1330 1165886 NP_697263.1 CDS soxB NC_004310.3 240071 241324 D identified by similarity to SP:P40875; match to protein family HMM PF01266; match to protein family HMM TIGR01373; sarcosine oxidase subunit beta 240071..241324 Brucella suis 1330 1165887 NP_697264.1 CDS soxD NC_004310.3 241343 241648 D identified by similarity to EGAD:43131; match to protein family HMM PF04267; match to protein family HMM TIGR01374; sarcosine oxidase subunit delta 241343..241648 Brucella suis 1330 1165888 NP_697265.1 CDS soxA NC_004310.3 241648 244647 D identified by similarity to EGAD:43132; match to protein family HMM PF01571; match to protein family HMM TIGR01372; sarcosine oxidase subunit alpha 241648..244647 Brucella suis 1330 1165889 NP_697266.1 CDS soxG NC_004310.3 244658 245212 D identified by similarity to EGAD:43133; match to protein family HMM PF04268; sarcosine oxidase subunit gamma 244658..245212 Brucella suis 1330 1165890 NP_697267.1 CDS BR0233 NC_004310.3 245265 246113 R identified by similarity to OMNI:NTL02ML5639; hypothetical protein complement(245265..246113) Brucella suis 1330 1165891 NP_697268.1 CDS BR0234 NC_004310.3 246171 246965 R identified by match to protein family HMM PF01614; IclR family transcriptional regulator complement(246171..246965) Brucella suis 1330 1165892 NP_697269.1 CDS BR0235 NC_004310.3 247123 248442 D identified by match to protein family HMM PF01547; sugar ABC transporter periplasmic sugar-binding protein 247123..248442 Brucella suis 1330 1165893 NP_697270.1 CDS BR0236 NC_004310.3 248503 249426 D identified by match to protein family HMM PF00528; sugar ABC transporter permease 248503..249426 Brucella suis 1330 1165894 NP_697271.1 CDS BR0237 NC_004310.3 249429 250304 D identified by match to protein family HMM PF00528; sugar ABC transporter permease 249429..250304 Brucella suis 1330 1165895 NP_697272.1 CDS BR0238 NC_004310.3 250312 251403 D identified by similarity to SP:Q00752; match to protein family HMM PF00005; match to protein family HMM PF03459; sugar ABC transporter ATP-binding protein 250312..251403 Brucella suis 1330 1165896 NP_697273.1 CDS BR0239 NC_004310.3 251406 252524 D identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase 251406..252524 Brucella suis 1330 1165897 NP_697274.1 CDS BR0240 NC_004310.3 252521 252865 D identified by similarity to GP:15140572; match to protein family HMM PF05336; hypothetical protein 252521..252865 Brucella suis 1330 1165898 NP_697275.1 CDS BR0241 NC_004310.3 252858 253937 D identified by match to protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 252858..253937 Brucella suis 1330 1165899 NP_697276.1 CDS BR0242 NC_004310.3 253940 254038 D hypothetical protein 253940..254038 Brucella suis 1330 1165900 NP_697277.1 CDS BR0243 NC_004310.3 254042 254776 D identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 254042..254776 Brucella suis 1330 1165901 NP_697278.1 CDS BR0244 NC_004310.3 254817 255662 D identified by similarity to GP:15140576; match to protein family HMM PF01557; fumarylacetoacetate hydrolase 254817..255662 Brucella suis 1330 1165902 NP_697279.1 CDS BR0245 NC_004310.3 255676 256953 D identified by match to protein family HMM PF01188; mandelate racemase 255676..256953 Brucella suis 1330 1165903 NP_697280.1 CDS BR0246 NC_004310.3 257352 257903 R hypothetical protein complement(257352..257903) Brucella suis 1330 1165904 NP_697281.1 CDS BR0247 NC_004310.3 259175 259348 R identified by similarity to OMNI:NTL02ML5069; match to protein family HMM PF03884; zinc-binding protein complement(259175..259348) Brucella suis 1330 1165906 NP_697282.1 CDS maf NC_004310.3 259400 260026 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(259400..260026) Brucella suis 1330 1165907 NP_697283.1 CDS infA NC_004310.3 260060 260278 R stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 complement(260060..260278) Brucella suis 1330 1165908 NP_697284.1 CDS BR0250 NC_004310.3 260390 260863 R identified by match to protein family HMM PF01451; protein phosphatase complement(260390..260863) Brucella suis 1330 1165909 NP_697285.1 CDS BR0251 NC_004310.3 260870 261352 R identified by similarity to OMNI:NTL02ML5073; hypothetical protein complement(260870..261352) Brucella suis 1330 1165910 NP_697286.1 CDS hisD NC_004310.3 261359 262651 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(261359..262651) Brucella suis 1330 1165911 NP_697287.1 CDS BR0253 NC_004310.3 262726 263166 R identified by similarity to GP:15073540; hypothetical protein complement(262726..263166) Brucella suis 1330 1165912 NP_697288.1 CDS murA NC_004310.3 263437 264726 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(263437..264726) Brucella suis 1330 1165913 NP_697289.1 CDS BR0255 NC_004310.3 264949 265128 R identified by similarity to OMNI:NTL02ML5077; hypothetical protein complement(264949..265128) Brucella suis 1330 1165914 NP_697290.1 CDS BR0256 NC_004310.3 265442 267196 D identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase site specific recombinase 265442..267196 Brucella suis 1330 1165916 NP_697291.1 CDS BR0257 NC_004310.3 267186 267299 R hypothetical protein complement(267186..267299) Brucella suis 1330 1165917 NP_697292.1 CDS BR0258 NC_004310.3 267291 267713 D identified by match to protein family HMM PF02498; BRO family protein 267291..267713 Brucella suis 1330 1165918 NP_697293.1 CDS BR0259 NC_004310.3 267726 267920 D hypothetical protein 267726..267920 Brucella suis 1330 1165919 NP_697294.1 CDS BR0260 NC_004310.3 268512 269129 D identified by match to protein family HMM PF00239; resolvase site-specific recombinase 268512..269129 Brucella suis 1330 1165920 NP_697295.1 CDS BR0261 NC_004310.3 269687 271051 D hypothetical protein 269687..271051 Brucella suis 1330 1165921 NP_697296.1 CDS BR0262 NC_004310.3 271639 271818 D hypothetical protein 271639..271818 Brucella suis 1330 1165922 NP_697297.1 CDS BR0263 NC_004310.3 272292 272576 R hypothetical protein complement(272292..272576) Brucella suis 1330 1165923 NP_697298.1 CDS BR0264 NC_004310.3 272690 272950 R identified by similarity to OMNI:NTL02ML3521; hypothetical protein complement(272690..272950) Brucella suis 1330 1165924 NP_697299.1 CDS BR0265 NC_004310.3 273034 273423 D hypothetical protein 273034..273423 Brucella suis 1330 1165925 NP_697300.1 CDS BR0266 NC_004310.3 273876 273980 R hypothetical protein complement(273876..273980) Brucella suis 1330 1165926 NP_697301.1 CDS ureD-1 NC_004310.3 274015 274857 D identified by similarity to SP:P42888; match to protein family HMM PF01774; urease accessory protein UreD 274015..274857 Brucella suis 1330 1165927 NP_697302.1 CDS ureA NC_004310.3 275010 275312 D UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 275010..275312 Brucella suis 1330 1165928 NP_697303.1 CDS ureB NC_004310.3 275479 275784 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active; urease subunit beta 275479..275784 Brucella suis 1330 1165929 NP_697304.1 CDS ureC NC_004310.3 275803 277515 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 275803..277515 Brucella suis 1330 1165930 NP_697305.1 CDS ureE NC_004310.3 277531 278019 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 277531..278019 Brucella suis 1330 1165931 NP_697306.1 CDS BR0272 NC_004310.3 277991 278677 D identified by similarity to SP:Q07402; match to protein family HMM PF01730; urease accessory protein UreF 277991..278677 Brucella suis 1330 1165932 NP_697307.1 CDS ureG-1 NC_004310.3 278674 279300 D identified by similarity to EGAD:19477; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 278674..279300 Brucella suis 1330 1165933 NP_697308.1 CDS BR0274 NC_004310.3 279657 281282 R identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase complement(279657..281282) Brucella suis 1330 1165935 NP_697309.1 CDS BR0275 NC_004310.3 281299 281604 R hypothetical protein complement(281299..281604) Brucella suis 1330 1165936 NP_697310.1 CDS BR0276 NC_004310.3 281567 282718 D identified by similarity to GP:15075163; match to protein family HMM TIGR01730; transporter 281567..282718 Brucella suis 1330 1165937 NP_697311.1 CDS BR0277 NC_004310.3 282733 285864 D identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein 282733..285864 Brucella suis 1330 1165938 NP_697312.1 CDS dhT NC_004310.3 285987 287456 R catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position; phenylhydantoinase complement(285987..287456) Brucella suis 1330 1165939 NP_697313.1 CDS BR0279 NC_004310.3 287508 288755 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(287508..288755) Brucella suis 1330 1165940 NP_697314.1 CDS BR0280 NC_004310.3 288974 289657 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 288974..289657 Brucella suis 1330 1165941 NP_697315.1 CDS BR0281 NC_004310.3 289654 290043 D identified by match to protein family HMM PF00293; MutT/nudix family protein 289654..290043 Brucella suis 1330 1165942 NP_697316.1 CDS BR0282 NC_004310.3 290088 291398 R catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines; dihydropyrimidine dehydrogenase complement(290088..291398) Brucella suis 1330 1165943 NP_697317.1 CDS BR0283 NC_004310.3 291402 292907 R function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain; oxidoreductase complement(291402..292907) Brucella suis 1330 1165944 NP_697318.1 CDS BR0284 NC_004310.3 293086 293538 R identified by similarity to GP:15073317; hypothetical protein complement(293086..293538) Brucella suis 1330 1165945 NP_697319.1 CDS pgi NC_004310.3 293689 295338 D functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 293689..295338 Brucella suis 1330 1165946 NP_697320.1 CDS BR0286 NC_004310.3 295574 296635 D identified by similarity to GP:15073237; hypothetical protein 295574..296635 Brucella suis 1330 1165947 NP_697321.1 CDS BR0287 NC_004310.3 296632 297381 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549; HAD superfamily hydrolase 296632..297381 Brucella suis 1330 1165948 NP_697322.1 CDS BR0288 NC_004310.3 297354 298226 R identified by similarity to OMNI:NTL03PA01240; hypothetical protein complement(297354..298226) Brucella suis 1330 1165949 NP_697323.1 CDS fadD NC_004310.3 298252 299916 R activates fatty acids by binding to coenzyme A; Long-chain-fatty-acid--CoA ligase complement(298252..299916) Brucella suis 1330 1165950 NP_697324.1 CDS BR0290 NC_004310.3 300348 300977 R identified by match to protein family HMM PF00440; TetR family transcriptional regulator complement(300348..300977) Brucella suis 1330 1165951 NP_697325.1 CDS BR0291 NC_004310.3 301150 302343 D identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein 301150..302343 Brucella suis 1330 1165952 NP_697326.1 CDS BR0292 NC_004310.3 302340 305495 D identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915; hydrophobe/amphiphile efflux-1 family protein 302340..305495 Brucella suis 1330 1165953 NP_697327.1 CDS BR0293 NC_004310.3 305606 305773 R hypothetical protein complement(305606..305773) Brucella suis 1330 1165954 NP_697328.1 CDS BR0294 NC_004310.3 305994 306134 R hypothetical protein complement(305994..306134) Brucella suis 1330 1165955 NP_697329.1 CDS BR0295 NC_004310.3 306203 307045 R identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein complement(306203..307045) Brucella suis 1330 1165956 NP_697330.1 CDS BR0296 NC_004310.3 307311 309203 D identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein 307311..309203 Brucella suis 1330 1165957 NP_697331.1 CDS BR0297 NC_004310.3 309131 310090 R identified by similarity to GP:15155336; match to protein family HMM PF03976; hypothetical protein complement(309131..310090) Brucella suis 1330 1165958 NP_697332.1 CDS BR0298 NC_004310.3 310223 311539 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 310223..311539 Brucella suis 1330 1165959 NP_697333.1 CDS BR0299 NC_004310.3 311669 312211 R identified by similarity to GP:15073446; hypothetical protein complement(311669..312211) Brucella suis 1330 1165960 NP_697334.1 CDS BR0300 NC_004310.3 312383 312724 R hypothetical protein complement(312383..312724) Brucella suis 1330 1165961 NP_697335.1 CDS argD NC_004310.3 312814 314025 D DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase 312814..314025 Brucella suis 1330 1165962 NP_697336.1 CDS argF NC_004310.3 314030 314968 D catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 314030..314968 Brucella suis 1330 1165963 NP_697337.1 CDS hslO NC_004310.3 314970 315992 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; heat shock protein 33 314970..315992 Brucella suis 1330 1165964 NP_697338.1 CDS apaG NC_004310.3 316033 316425 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(316033..316425) Brucella suis 1330 1165965 NP_697339.1 CDS metZ NC_004310.3 316794 317990 R catalyzes the conversion of O-succinylhomoserine and sulfide to homocysteine; second step in methionine biosynthesis; O-succinylhomoserine sulfhydrylase complement(316794..317990) Brucella suis 1330 1165966 NP_697340.1 CDS BR0306 NC_004310.3 318417 319508 D Catalyzes the deamination of dCTP to form dUTP; 2'-deoxycytidine 5'-triphosphate deaminase 318417..319508 Brucella suis 1330 1165967 NP_697341.1 CDS BR0307 NC_004310.3 319599 320615 D identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 319599..320615 Brucella suis 1330 1165968 NP_697342.1 CDS BR0308 NC_004310.3 320702 320968 D identified by similarity to GP:15155415; hypothetical protein 320702..320968 Brucella suis 1330 1165969 NP_697343.1 CDS BR0309 NC_004310.3 321068 321487 D identified by similarity to OMNI:NTL02ML6482; match to protein family HMM PF00188; hypothetical protein 321068..321487 Brucella suis 1330 1165970 NP_697344.1 CDS BR0310 NC_004310.3 321662 323029 D identified by similarity to EGAD:8949; match to protein family HMM PF01554; match to protein family HMM TIGR00797; DNA-damage-inducible protein F 321662..323029 Brucella suis 1330 1165971 NP_697345.1 CDS pyrD NC_004310.3 323031 324125 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(323031..324125) Brucella suis 1330 1165972 NP_697346.1 CDS BR0312 NC_004310.3 324122 324475 R identified by similarity to GP:15073480; hypothetical protein complement(324122..324475) Brucella suis 1330 1165973 NP_697347.1 CDS BR0313 NC_004310.3 324729 325184 D identified by similarity to OMNI:NTL02ML4408; hypothetical protein 324729..325184 Brucella suis 1330 1165974 NP_697348.1 CDS pip NC_004310.3 325275 326225 R identified by similarity to EGAD:139406; match to protein family HMM PF00561; match to protein family HMM TIGR01249; proline iminopeptidase complement(325275..326225) Brucella suis 1330 1165975 NP_697349.1 CDS BR0315 NC_004310.3 326455 327096 D identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 326455..327096 Brucella suis 1330 1165976 NP_697350.1 CDS BR0316 NC_004310.3 327133 330657 R identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase/response regulator complement(327133..330657) Brucella suis 1330 1165977 NP_697351.1 CDS BR0317 NC_004310.3 330942 331088 R hypothetical protein complement(330942..331088) Brucella suis 1330 1165978 NP_697352.1 CDS mscL NC_004310.3 331170 331586 D homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 331170..331586 Brucella suis 1330 1165979 NP_697353.1 CDS hemA NC_004310.3 331662 332939 R catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase complement(331662..332939) Brucella suis 1330 1165980 NP_697354.1 CDS BR0320 NC_004310.3 333085 333786 R identified by match to protein family HMM PF01522; polysaccharide deacetylase complement(333085..333786) Brucella suis 1330 1165981 NP_697355.1 CDS BR0321 NC_004310.3 333795 334514 R identified by similarity to GP:12837556; match to protein family HMM PF01755; glycosyl transferase complement(333795..334514) Brucella suis 1330 1165982 NP_697356.1 CDS BR0322 NC_004310.3 334644 335318 R identified by similarity to GP:15157577; hypothetical protein complement(334644..335318) Brucella suis 1330 1165983 NP_697357.1 CDS BR0323 NC_004310.3 335410 335643 R hypothetical protein complement(335410..335643) Brucella suis 1330 1165984 NP_697358.1 CDS BR0324 NC_004310.3 335686 336576 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(335686..336576) Brucella suis 1330 1165985 NP_697359.1 CDS BR0325 NC_004310.3 336698 337117 D identified by similarity to OMNI:NTL03PA03432; match to protein family HMM PF03788; hypothetical protein 336698..337117 Brucella suis 1330 1165986 NP_697360.1 CDS BR0326 NC_004310.3 337104 337811 D identified by similarity to OMNI:NTL03PA03431; match to protein family HMM PF04172; hypothetical protein 337104..337811 Brucella suis 1330 1165987 NP_697361.1 CDS BR0327 NC_004310.3 337934 338320 D hypothetical protein 337934..338320 Brucella suis 1330 1165988 NP_697362.1 CDS BR0328 NC_004310.3 338358 339599 D identified by similarity to GP:15155313; lipoprotein 338358..339599 Brucella suis 1330 1165989 NP_697363.1 CDS panC NC_004310.3 339686 340567 D catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 339686..340567 Brucella suis 1330 1165990 NP_697364.1 CDS panB NC_004310.3 340569 341396 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 340569..341396 Brucella suis 1330 1165991 NP_697365.1 CDS fpr NC_004310.3 341593 342369 R identified by similarity to SP:Q44532; match to protein family HMM PF00175; match to protein family HMM PF00970; ferredoxin-NADP reductase complement(341593..342369) Brucella suis 1330 1165992 NP_697366.1 CDS BR0332 NC_004310.3 342491 342583 D hypothetical protein 342491..342583 Brucella suis 1330 1165993 NP_697367.1 CDS BR0333 NC_004310.3 342772 343122 D hypothetical protein 342772..343122 Brucella suis 1330 1165994 NP_697368.1 CDS nspC NC_004310.3 343161 344258 D identified by similarity to EGAD:19651; match to protein family HMM PF00278; match to protein family HMM TIGR01047; carboxynorspermidine decarboxylase 343161..344258 Brucella suis 1330 1165995 NP_697369.1 CDS BR0335 NC_004310.3 344439 345680 D identified by similarity to GP:15141437; match to protein family HMM PF03435; hypothetical protein 344439..345680 Brucella suis 1330 1165996 NP_697370.1 CDS BR0336 NC_004310.3 345696 345911 R hypothetical protein complement(345696..345911) Brucella suis 1330 1165997 NP_697371.1 CDS BR0337 NC_004310.3 345936 346964 R identified by similarity to GP:9695312; match to protein family HMM PF05544; proline racemase complement(345936..346964) Brucella suis 1330 1165998 NP_697372.1 CDS BR0338 NC_004310.3 347019 347126 R hypothetical protein complement(347019..347126) Brucella suis 1330 1165999 NP_697373.1 CDS BR0339 NC_004310.3 347417 348832 D identified by similarity to SP:O82855; match to protein family HMM PF01554; match to protein family HMM TIGR00797; multidrug resistance protein NorM 347417..348832 Brucella suis 1330 1166000 NP_697374.1 CDS BR0342 NC_004310.3 351026 351667 D identified by match to protein family HMM PF00072; match to protein family HMM PF00196; LuxR family transcriptional regulator 351026..351667 Brucella suis 1330 1166003 NP_697375.1 CDS BR0343 NC_004310.3 351955 352503 D identified by similarity to GP:15162042; match to protein family HMM PF04290; hypothetical protein 351955..352503 Brucella suis 1330 1166004 NP_697376.1 CDS BR0344 NC_004310.3 352515 354083 D identified by match to protein family HMM TIGR00786; TRAP dicarboxylate transporter subunit DctM 352515..354083 Brucella suis 1330 1166005 NP_697377.1 CDS BR0345 NC_004310.3 354145 355263 D identified by match to protein family HMM PF03480; match to protein family HMM TIGR01409; ABC transporter substrate-binding protein 354145..355263 Brucella suis 1330 1166006 NP_697378.1 CDS BR0346 NC_004310.3 355346 356164 R identified by similarity to OMNI:NTL02ML3955; hypothetical protein complement(355346..356164) Brucella suis 1330 1166007 NP_697379.1 CDS BR0347 NC_004310.3 356177 357604 R identified by similarity to OMNI:NTL02ML3956; match to protein family HMM PF01522; hypothetical protein complement(356177..357604) Brucella suis 1330 1166008 NP_697380.1 CDS BR0348 NC_004310.3 357872 358147 D identified by similarity to GP:15140674; hypothetical protein 357872..358147 Brucella suis 1330 1166009 NP_697381.1 CDS BR0349 NC_004310.3 358153 359631 D identified by similarity to OMNI:NTL02ML3958; match to protein family HMM PF00111; match to protein family HMM PF00941; match to protein family HMM PF01799; match to protein family HMM PF03450; xanthine dehydrogenase 358153..359631 Brucella suis 1330 1166010 NP_697382.1 CDS BR0350 NC_004310.3 359644 361986 D identified by match to protein family HMM PF01315; match to protein family HMM PF02738; xanthine dehydrogenase 359644..361986 Brucella suis 1330 1166011 NP_697383.1 CDS BR0351 NC_004310.3 362117 362863 D identified by similarity to OMNI:CC2617; chaperone XdhC 362117..362863 Brucella suis 1330 1166012 NP_697384.1 CDS BR0352 NC_004310.3 362944 363858 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(362944..363858) Brucella suis 1330 1166013 NP_697385.1 CDS BR0353 NC_004310.3 364039 365283 D identified by similarity to GP:15140681; hypothetical protein 364039..365283 Brucella suis 1330 1166014 NP_697386.1 CDS BR0354 NC_004310.3 365280 366584 D Catalyzes the deamination of guanine; guanine deaminase 365280..366584 Brucella suis 1330 1166015 NP_697387.1 CDS BR0355 NC_004310.3 366664 367950 D identified by similarity to EGAD:40602; match to protein family HMM PF05161; hydroxypyruvate reductase 366664..367950 Brucella suis 1330 1166016 NP_697388.1 CDS ccoS NC_004310.3 367931 368089 R identified by match to protein family HMM PF03597; match to protein family HMM TIGR00847; cbb3-type cytochrome oxidase maturation protein complement(367931..368089) Brucella suis 1330 1166017 NP_697389.1 CDS BR0357 NC_004310.3 368086 370344 R identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525; nitrogen fixation protein FixI complement(368086..370344) Brucella suis 1330 1166018 NP_697390.1 CDS BR0358 NC_004310.3 370341 370838 R identified by similarity to EGAD:10086; match to protein family HMM PF05751; nitrogen fixation protein FixH complement(370341..370838) Brucella suis 1330 1166019 NP_697391.1 CDS BR0359 NC_004310.3 370838 372388 R (Fe-S)-binding protein complement(370838..372388) Brucella suis 1330 1166020 NP_697392.1 CDS ccoP NC_004310.3 372548 373411 R identified by match to protein family HMM PF00034; match to protein family HMM TIGR00782; cytochrome c oxidase, cbb3-type subunit III complement(372548..373411) Brucella suis 1330 1166021 NP_697393.1 CDS ccoQ NC_004310.3 373404 373562 R identified by similarity to EGAD:125983; match to protein family HMM PF05545; cytochrome c oxidase, cbb3-type, CcoQ subunit complement(373404..373562) Brucella suis 1330 1166022 NP_697394.1 CDS ccoO NC_004310.3 373577 374308 R CcoO; FixO; cbb3-type cytochrome c oxidase subunit II complement(373577..374308) Brucella suis 1330 1166023 NP_697395.1 CDS ccoN NC_004310.3 374323 375948 R CcoN; FixN; cbb3-type cytochrome c oxidase subunit I complement(374323..375948) Brucella suis 1330 1166024 NP_697396.1 CDS BR0364 NC_004310.3 376166 376624 R identified by match to protein family HMM PF01475; FUR family transcriptional regulator complement(376166..376624) Brucella suis 1330 1166025 NP_697397.1 CDS BR0365 NC_004310.3 376623 376949 D hypothetical protein 376623..376949 Brucella suis 1330 1166026 NP_697398.1 CDS BR0366 NC_004310.3 377066 377680 D identified by similarity to GP:13235366; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 377066..377680 Brucella suis 1330 1166027 NP_697399.1 CDS BR0367 NC_004310.3 377729 379174 R identified by match to protein family HMM PF00171; aldehyde dehydrogenase complement(377729..379174) Brucella suis 1330 1166028 NP_697400.1 CDS ada NC_004310.3 379373 380458 D identified by similarity to EGAD:7337; match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM TIGR00589; ada regulatory protein 379373..380458 Brucella suis 1330 1166029 NP_697401.1 CDS BR0369 NC_004310.3 380640 380990 D identified by similarity to GP:15073235; match to protein family HMM PF03960; match to protein family HMM TIGR01617; hypothetical protein 380640..380990 Brucella suis 1330 1166030 NP_697402.1 CDS BR0370 NC_004310.3 381327 382370 D identified by similarity to GP:15156192; hypothetical protein 381327..382370 Brucella suis 1330 1166031 NP_697403.1 CDS bacA NC_004310.3 383821 385068 D in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope; transport protein 383821..385068 Brucella suis 1330 1166033 NP_697404.1 CDS BR0373 NC_004310.3 385107 386105 R identified by similarity to OMNI:NTL02ML5836; hypothetical protein complement(385107..386105) Brucella suis 1330 1166034 NP_697405.1 CDS BR0374 NC_004310.3 386351 387022 D identified by similarity to OMNI:NTL02ML5837; hypothetical protein 386351..387022 Brucella suis 1330 1166035 NP_697406.1 CDS engA NC_004310.3 387044 388495 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 387044..388495 Brucella suis 1330 1166036 NP_697407.1 CDS BR0376 NC_004310.3 388654 389970 D identified by similarity to SP:P04475; molecular chaperone DnaK 388654..389970 Brucella suis 1330 1166037 NP_697408.1 CDS BR0377 NC_004310.3 390060 390185 R hypothetical protein complement(390060..390185) Brucella suis 1330 1166038 NP_697409.1 CDS BR0378 NC_004310.3 390407 391696 D identified by similarity to GP:14026921; hypothetical protein 390407..391696 Brucella suis 1330 1166039 NP_697410.1 CDS BR0379 NC_004310.3 391724 391828 D hypothetical protein 391724..391828 Brucella suis 1330 1166040 NP_697411.1 CDS BR0380 NC_004310.3 391858 391983 D hypothetical protein 391858..391983 Brucella suis 1330 1166041 NP_697412.1 CDS BR0381 NC_004310.3 391967 392365 D identified by similarity to EGAD:21946; ATP sythase I 391967..392365 Brucella suis 1330 1166042 NP_697413.1 CDS atpB NC_004310.3 392473 393222 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 392473..393222 Brucella suis 1330 1166043 NP_697414.1 CDS atpE NC_004310.3 393290 393517 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 393290..393517 Brucella suis 1330 1166044 NP_697415.1 CDS BR0384 NC_004310.3 393689 394315 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B' is part of the membrane proton channel.; ATP synthase F0F1 subunit B' 393689..394315 Brucella suis 1330 1166045 NP_697416.1 CDS atpF NC_004310.3 394326 394805 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 394326..394805 Brucella suis 1330 1166046 NP_697417.1 CDS rnhB NC_004310.3 394928 395590 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(394928..395590) Brucella suis 1330 1166047 NP_697418.1 CDS BR0387 NC_004310.3 395767 396939 R identified by similarity to GP:15073771; match to protein family HMM PF04055; hypothetical protein complement(395767..396939) Brucella suis 1330 1166048 NP_697419.1 CDS BR0388 NC_004310.3 397075 397581 D identified by similarity to GP:15155690; hypothetical protein 397075..397581 Brucella suis 1330 1166049 NP_697420.1 CDS BR0389 NC_004310.3 397661 397933 R hypothetical protein complement(397661..397933) Brucella suis 1330 1166050 NP_697421.1 CDS BR0390 NC_004310.3 397923 398030 D hypothetical protein 397923..398030 Brucella suis 1330 1166051 NP_697422.1 CDS BR0391 NC_004310.3 398077 398352 R hypothetical protein complement(398077..398352) Brucella suis 1330 1166052 NP_697423.1 CDS BR0392 NC_004310.3 398424 398657 R hypothetical protein complement(398424..398657) Brucella suis 1330 1166053 NP_697424.1 CDS BR0393 NC_004310.3 398620 398766 R hypothetical protein complement(398620..398766) Brucella suis 1330 1166054 NP_697425.1 CDS ispE NC_004310.3 398711 399610 R An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase complement(398711..399610) Brucella suis 1330 1166055 NP_697426.1 CDS BR0395 NC_004310.3 399640 399861 R hypothetical protein complement(399640..399861) Brucella suis 1330 1166056 NP_697427.1 CDS BR0396 NC_004310.3 400292 401398 R identified by match to protein family HMM PF01343; endopeptidase IV complement(400292..401398) Brucella suis 1330 1166057 NP_697428.1 CDS nhaA NC_004310.3 401319 402500 R exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH; pH-dependent sodium/proton antiporter complement(401319..402500) Brucella suis 1330 1166058 NP_697429.1 CDS BR0398 NC_004310.3 402520 402741 R hypothetical protein complement(402520..402741) Brucella suis 1330 1166059 NP_697430.1 CDS BR0399 NC_004310.3 402790 403548 R identified by similarity to GP:15073779; hypothetical protein complement(402790..403548) Brucella suis 1330 1166060 NP_697431.1 CDS BR0400 NC_004310.3 403569 403796 R identified by similarity to GP:15073778; hypothetical protein complement(403569..403796) Brucella suis 1330 1166061 NP_697432.1 CDS BR0401 NC_004310.3 404059 405081 D identified by match to protein family HMM PF00348; polyprenyl synthetase 404059..405081 Brucella suis 1330 1166062 NP_697433.1 CDS BR0402 NC_004310.3 405385 407250 D identified by match to protein family HMM PF00515; TPR domain-containing protein 405385..407250 Brucella suis 1330 1166063 NP_697434.1 CDS glyQ NC_004310.3 407402 408328 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 407402..408328 Brucella suis 1330 1166064 NP_697435.1 CDS glyS NC_004310.3 408447 410780 D glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta 408447..410780 Brucella suis 1330 1166065 NP_697436.1 CDS BR0405 NC_004310.3 410919 411890 D identified by match to protein family HMM PF01300; match to protein family HMM PF03481; match to protein family HMM TIGR00057; Sua5/YciO/YrdC family protein 410919..411890 Brucella suis 1330 1166066 NP_697437.1 CDS BR0406 NC_004310.3 411916 413328 D identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD-binding oxidoreductase 411916..413328 Brucella suis 1330 1166067 NP_697438.1 CDS BR0407 NC_004310.3 413366 413683 R identified by similarity to OMNI:VCA0423; match to protein family HMM PF05016; hypothetical protein complement(413366..413683) Brucella suis 1330 1166068 NP_697439.1 CDS BR0408 NC_004310.3 413680 413940 R identified by similarity to GP:3337067; hypothetical protein complement(413680..413940) Brucella suis 1330 1166069 NP_697440.1 CDS BR0409 NC_004310.3 414049 414222 R hypothetical protein complement(414049..414222) Brucella suis 1330 1166070 NP_697441.1 CDS BR0410 NC_004310.3 414251 414817 D identified by similarity to GP:15155604; hypothetical protein 414251..414817 Brucella suis 1330 1166071 NP_697442.1 CDS BR0411 NC_004310.3 414960 415712 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(414960..415712) Brucella suis 1330 1166072 NP_697443.1 CDS BR0412 NC_004310.3 415715 417493 R identified by match to protein family HMM PF00441; match to protein family HMM PF02770; acyl-CoA dehydrogenase complement(415715..417493) Brucella suis 1330 1166073 NP_697444.1 CDS purD NC_004310.3 418974 420257 R catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase complement(418974..420257) Brucella suis 1330 1166075 NP_697445.1 CDS ubiA NC_004310.3 420402 421403 D UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 420402..421403 Brucella suis 1330 1166076 NP_697446.1 CDS pdxH NC_004310.3 421443 422069 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate; pyridoxamine 5'-phosphate oxidase complement(421443..422069) Brucella suis 1330 1166077 NP_697447.1 CDS BR0417 NC_004310.3 422328 422798 D identified by similarity to GP:14026958; hypothetical protein 422328..422798 Brucella suis 1330 1166078 NP_697448.1 CDS BR0418 NC_004310.3 422943 423884 D identified by match to protein family HMM PF00226; match to protein family HMM PF01556; molecular chaperone DnaJ 422943..423884 Brucella suis 1330 1166079 NP_697449.1 CDS BR0419 NC_004310.3 423888 423995 R hypothetical protein complement(423888..423995) Brucella suis 1330 1166080 NP_697450.1 CDS fabI-1 NC_004310.3 424028 424846 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 424028..424846 Brucella suis 1330 1166081 NP_697451.1 CDS BR0422 NC_004310.3 425676 425855 R hypothetical protein complement(425676..425855) Brucella suis 1330 1166083 NP_697452.1 CDS BR0424 NC_004310.3 426109 426258 R hypothetical protein complement(426109..426258) Brucella suis 1330 1166085 NP_697453.1 CDS BR0425 NC_004310.3 426514 426693 D identified by similarity to GP:15160282; hypothetical protein 426514..426693 Brucella suis 1330 1166086 NP_697454.1 CDS BR0426 NC_004310.3 426788 427450 D identified by similarity to GP:14027592; match to protein family HMM PF04028; hypothetical protein 426788..427450 Brucella suis 1330 1166087 NP_697455.1 CDS BR0427 NC_004310.3 427595 427846 R identified by similarity to GP:15073831; hypothetical protein complement(427595..427846) Brucella suis 1330 1166088 NP_697456.1 CDS aroC NC_004310.3 428122 429216 D catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 428122..429216 Brucella suis 1330 1166089 NP_697457.1 CDS ribAB NC_004310.3 429352 430467 D identified by match to protein family HMM PF00925; match to protein family HMM PF00926; match to protein family HMM TIGR00506; 3,4-dihydroxy-2-butanone-4-phosphate synthase 429352..430467 Brucella suis 1330 1166090 NP_697458.1 CDS BR0430 NC_004310.3 430620 431633 D identified by match to protein family HMM PF00850; histone deacetylase 430620..431633 Brucella suis 1330 1166091 NP_697459.1 CDS xseB NC_004310.3 431638 431892 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 431638..431892 Brucella suis 1330 1166092 NP_697460.1 CDS BR0432 NC_004310.3 431899 432417 R identified by match to protein family HMM PF00597; dedA family protein complement(431899..432417) Brucella suis 1330 1166093 NP_697461.1 CDS BR0433 NC_004310.3 432659 432919 R identified by similarity to OMNI:NTL02ML3629; match to protein family HMM PF04226; transglycosylase-associated protein complement(432659..432919) Brucella suis 1330 1166094 NP_697462.1 CDS BR0434 NC_004310.3 433082 433633 D identified by similarity to OMNI:NTL02ML3630; hypothetical protein 433082..433633 Brucella suis 1330 1166095 NP_697463.1 CDS BR0435 NC_004310.3 433837 434709 D identified by similarity to OMNI:CC3178; match to protein family HMM PF02678; match to protein family HMM PF05726; pirin 433837..434709 Brucella suis 1330 1166096 NP_697464.1 CDS dxs NC_004310.3 434852 436783 D catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 434852..436783 Brucella suis 1330 1166097 NP_697465.1 CDS tlyA NC_004310.3 436789 437550 D identified by similarity to EGAD:20008; match to protein family HMM PF01479; match to protein family HMM PF01728; match to protein family HMM TIGR00478; hemolysin A 436789..437550 Brucella suis 1330 1166098 NP_697466.1 CDS BR0438 NC_004310.3 437547 438794 D RNA methyltransferase 437547..438794 Brucella suis 1330 1166099 NP_697467.1 CDS BR0439 NC_004310.3 438930 439532 R identified by similarity to GP:15074050; match to protein family HMM PF03641; match to protein family HMM TIGR00730; hypothetical protein complement(438930..439532) Brucella suis 1330 1166100 NP_697468.1 CDS BR0440 NC_004310.3 439662 440027 D identified by similarity to GP:15157092; hypothetical protein 439662..440027 Brucella suis 1330 1166101 NP_697469.1 CDS BR0441 NC_004310.3 440214 441428 D identified by match to protein family HMM PF01476; LysM domain-containing protein 440214..441428 Brucella suis 1330 1166102 NP_697470.1 CDS BR0442 NC_004310.3 441631 443517 D identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP-binding/permease 441631..443517 Brucella suis 1330 1166103 NP_697471.1 CDS BR0443 NC_004310.3 443622 444320 D catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 443622..444320 Brucella suis 1330 1166104 NP_697472.1 CDS pssA NC_004310.3 444325 445161 D identified by match to protein family HMM PF01066; match to protein family HMM TIGR00473; CDP-diacylglycerol--serine O-phosphatidyltransferase 444325..445161 Brucella suis 1330 1166105 NP_697473.1 CDS BR0445 NC_004310.3 445246 445986 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase complement(445246..445986) Brucella suis 1330 1166106 NP_697474.1 CDS purF NC_004310.3 446055 447512 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(446055..447512) Brucella suis 1330 1166107 NP_697475.1 CDS BR0447 NC_004310.3 447489 447731 D hypothetical protein 447489..447731 Brucella suis 1330 1166108 NP_697476.1 CDS BR0448 NC_004310.3 447827 448405 R identified by similarity to OMNI:NTL02ML6179; match to protein family HMM PF02674; colicin V production protein complement(447827..448405) Brucella suis 1330 1166109 NP_697477.1 CDS radA NC_004310.3 448531 449934 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(448531..449934) Brucella suis 1330 1166110 NP_697478.1 CDS dnaB NC_004310.3 449962 451467 R unwinds double stranded DNA; replicative DNA helicase complement(449962..451467) Brucella suis 1330 1166111 NP_697479.1 CDS cfa NC_004310.3 451666 452946 R identified by similarity to SP:P30010; match to protein family HMM PF02353; cyclopropane-fatty-acyl-phospholipid synthase complement(451666..452946) Brucella suis 1330 1166112 NP_697480.1 CDS rplI NC_004310.3 453320 453889 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(453320..453889) Brucella suis 1330 1166113 NP_697481.1 CDS BR0453 NC_004310.3 453919 454890 R identified by similarity to GP:15074068; hypothetical protein complement(453919..454890) Brucella suis 1330 1166114 NP_697482.1 CDS rpsR NC_004310.3 455041 455289 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(455041..455289) Brucella suis 1330 1166115 NP_697483.1 CDS rpsF NC_004310.3 455292 455738 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(455292..455738) Brucella suis 1330 1166116 NP_697484.1 CDS BR0456 NC_004310.3 455763 456122 R identified by similarity to OMNI:VC2163; hypothetical protein complement(455763..456122) Brucella suis 1330 1166117 NP_697485.1 CDS fabD NC_004310.3 456144 457088 D identified by similarity to EGAD:97846; match to protein family HMM PF00698; match to protein family HMM TIGR00128; ACP S-malonyltransferase 456144..457088 Brucella suis 1330 1166118 NP_697486.1 CDS fabG NC_004310.3 457158 457895 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 457158..457895 Brucella suis 1330 1166119 NP_697487.1 CDS acpP NC_004310.3 458169 458405 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 458169..458405 Brucella suis 1330 1166120 NP_697488.1 CDS BR0460 NC_004310.3 458409 458672 D hypothetical protein 458409..458672 Brucella suis 1330 1166121 NP_697489.1 CDS fabF NC_004310.3 458729 459991 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase 458729..459991 Brucella suis 1330 1166122 NP_697490.1 CDS BR0462 NC_004310.3 460216 461454 D identified by similarity to GP:15074077; match to protein family HMM PF02618; match to protein family HMM TIGR00247; hypothetical protein 460216..461454 Brucella suis 1330 1166123 NP_697491.1 CDS BR0463 NC_004310.3 461640 462539 D identified by similarity to OMNI:NTL02ML6198; match to protein family HMM PF03755; match to protein family HMM TIGR00255; hypothetical protein 461640..462539 Brucella suis 1330 1166124 NP_697492.1 CDS gmk NC_004310.3 462548 463210 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 462548..463210 Brucella suis 1330 1166125 NP_697493.1 CDS BR0465 NC_004310.3 463237 464649 R identified by similarity to EGAD:30245; match to protein family HMM PF01523; tldD protein complement(463237..464649) Brucella suis 1330 1166126 NP_697494.1 CDS BR0466 NC_004310.3 464791 465387 R identified by similarity to GP:15073834; hypothetical protein complement(464791..465387) Brucella suis 1330 1166127 NP_697495.1 CDS coxB NC_004310.3 465851 466705 D identified by similarity to EGAD:8295; match to protein family HMM PF00116; match to protein family HMM PF02790; cytochrome c oxidase subunit II 465851..466705 Brucella suis 1330 1166128 NP_697496.1 CDS coxA NC_004310.3 466843 468501 D identified by similarity to EGAD:5976; match to protein family HMM PF00115; cytochrome c oxidase subunit I 466843..468501 Brucella suis 1330 1166129 NP_697497.1 CDS ctaB NC_004310.3 468729 469676 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 468729..469676 Brucella suis 1330 1166130 NP_697498.1 CDS BR0470 NC_004310.3 469676 469861 D identified by similarity to OMNI:NTL02ML5908; hypothetical protein 469676..469861 Brucella suis 1330 1166131 NP_697499.1 CDS ctaG NC_004310.3 469881 470486 D involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 469881..470486 Brucella suis 1330 1166132 NP_697500.1 CDS coxC NC_004310.3 470695 471573 D identified by match to protein family HMM PF00510; cytochrome c oxidase subunit III 470695..471573 Brucella suis 1330 1166133 NP_697501.1 CDS BR0473 NC_004310.3 471687 472070 D identified by similarity to GP:14026992; hypothetical protein 471687..472070 Brucella suis 1330 1166134 NP_697502.1 CDS BR0474 NC_004310.3 472067 472816 D identified by match to protein family HMM PF02104; SurF1 family protein 472067..472816 Brucella suis 1330 1166135 NP_697503.1 CDS ispH NC_004310.3 472847 473965 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 472847..473965 Brucella suis 1330 1166136 NP_697504.1 CDS thrB NC_004310.3 473971 474951 D catalyzes the formation of O-phospho-L-homoserine from L-homoserine; homoserine kinase 473971..474951 Brucella suis 1330 1166137 NP_697505.1 CDS rnhA NC_004310.3 474948 475412 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease H 474948..475412 Brucella suis 1330 1166138 NP_697506.1 CDS BR0478 NC_004310.3 475442 475927 R identified by match to protein family HMM PF00578; ahpC/TSA family protein complement(475442..475927) Brucella suis 1330 1166139 NP_697507.1 CDS BR0479 NC_004310.3 476107 476907 R identified by similarity to OMNI:NTL02ML5920; hypothetical protein complement(476107..476907) Brucella suis 1330 1166140 NP_697508.1 CDS BR0480 NC_004310.3 477042 477644 D identified by similarity to OMNI:NTL02ML5921; match to protein family HMM PF02622; hypothetical protein 477042..477644 Brucella suis 1330 1166141 NP_697509.1 CDS BR0481 NC_004310.3 477742 480636 R identified by match to protein family HMM PF00563; match to protein family HMM PF00785; match to protein family HMM PF00990; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254; sensory box protein complement(477742..480636) Brucella suis 1330 1166142 NP_697510.1 CDS BR0482 NC_004310.3 480633 481253 R identified by match to protein family HMM PF00583; acetyltransferase complement(480633..481253) Brucella suis 1330 1166143 NP_697511.1 CDS BR0483 NC_004310.3 481424 482716 R identified by similarity to OMNI:NTL01BH2408; match to protein family HMM PF00675; match to protein family HMM PF05193; processing protease complement(481424..482716) Brucella suis 1330 1166144 NP_697512.1 CDS thrC NC_004310.3 482770 484161 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(482770..484161) Brucella suis 1330 1166145 NP_697513.1 CDS BR0485 NC_004310.3 484241 484432 R hypothetical protein complement(484241..484432) Brucella suis 1330 1166146 NP_697514.1 CDS BR0486 NC_004310.3 484583 485161 D lipoprotein 484583..485161 Brucella suis 1330 1166147 NP_697515.1 CDS BR0487 NC_004310.3 485475 487109 D identified by similarity to OMNI:NTL03PA02200; match to protein family HMM PF00563; diguanylate phosphodiesterase 485475..487109 Brucella suis 1330 1166148 NP_697516.1 CDS BR0488 NC_004310.3 487238 487423 D identified by similarity to OMNI:NTL02ML1736; hypothetical protein 487238..487423 Brucella suis 1330 1166149 NP_697517.1 CDS BR0489 NC_004310.3 487465 488151 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase complement(487465..488151) Brucella suis 1330 1166150 NP_697518.1 CDS BR0490 NC_004310.3 488299 490089 R identified by match to protein family HMM PF00654; voltage gated chloride channel family protein complement(488299..490089) Brucella suis 1330 1166151 NP_697519.1 CDS babI NC_004310.3 490426 491559 D identified by similarity to EGAD:154344; match to protein family HMM PF01555; modification methylase BabI 490426..491559 Brucella suis 1330 1166152 NP_697520.1 CDS BR0492 NC_004310.3 491642 492259 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; HAD superfamily hydrolase complement(491642..492259) Brucella suis 1330 1166153 NP_697521.1 CDS mutY NC_004310.3 492256 493332 R identified by similarity to EGAD:19424; match to protein family HMM PF00730; match to protein family HMM TIGR01084; A/G-specific adenine glycosylase complement(492256..493332) Brucella suis 1330 1166154 NP_697522.1 CDS BR0494 NC_004310.3 493606 494133 D identified by similarity to GP:15073860; hypothetical protein 493606..494133 Brucella suis 1330 1166155 NP_697523.1 CDS BR0495 NC_004310.3 494151 494324 D hypothetical protein 494151..494324 Brucella suis 1330 1166156 NP_697524.1 CDS BR0496 NC_004310.3 494371 495024 D identified by similarity to GP:15155781; match to protein family HMM PF01323; match to protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 494371..495024 Brucella suis 1330 1166157 NP_697525.1 CDS BR0497 NC_004310.3 495103 498561 D identified by similarity to OMNI:NTL02ML5933; match to protein family HMM PF02463; match to protein family HMM PF02483; match to protein family HMM TIGR02168; SMC family protein 495103..498561 Brucella suis 1330 1166158 NP_697526.1 CDS BR0498 NC_004310.3 498584 499477 D identified by similarity to SP:P13512; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cobalt-zinc-cadmium resistance protein 498584..499477 Brucella suis 1330 1166159 NP_697527.1 CDS BR0499 NC_004310.3 499587 499928 R identified by match to protein family HMM PF00903; glyoxalase complement(499587..499928) Brucella suis 1330 1166160 NP_697528.1 CDS ppdK NC_004310.3 500192 502855 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 500192..502855 Brucella suis 1330 1166161 NP_697529.1 CDS BR0502 NC_004310.3 504131 504277 R hypothetical protein complement(504131..504277) Brucella suis 1330 1166163 NP_697530.1 CDS BR0503 NC_004310.3 504274 504603 R hypothetical protein complement(504274..504603) Brucella suis 1330 1166164 NP_697531.1 CDS BR0504 NC_004310.3 504887 505675 D identified by similarity to OMNI:NTL02ML5941; hypothetical protein 504887..505675 Brucella suis 1330 1166165 NP_697532.1 CDS BR0505 NC_004310.3 505676 506581 R identified by match to protein family HMM PF00753; metallo-beta-lactamase complement(505676..506581) Brucella suis 1330 1166166 NP_697533.1 CDS BR0506 NC_004310.3 506782 507381 D identified by match to protein family HMM PF02632; BioY family protein 506782..507381 Brucella suis 1330 1166167 NP_697534.1 CDS BR0507 NC_004310.3 507535 508044 D catalyzes the formation of glyoxylate from (S)-ureidoglycolate; ureidoglycolate hydrolase 507535..508044 Brucella suis 1330 1166168 NP_697535.1 CDS BR0508 NC_004310.3 508056 508412 D identified by similarity to GP:15157490; match to protein family HMM PF00576; hypothetical protein 508056..508412 Brucella suis 1330 1166169 NP_697536.1 CDS BR0509 NC_004310.3 508483 509319 D identified by similarity to GP:15157607; hypothetical protein 508483..509319 Brucella suis 1330 1166170 NP_697537.1 CDS BR0510 NC_004310.3 509856 511724 D identified by similarity to GP:6009656; match to protein family HMM PF02719; epimerase 509856..511724 Brucella suis 1330 1166171 NP_697538.1 CDS BR0511 NC_004310.3 511711 512718 R identified by match to protein family HMM PF00953; glycosyl transferase group 4 family protein complement(511711..512718) Brucella suis 1330 1166172 YP_089629.1 CDS BR0513 NC_004310.3 513927 514870 D identified by similarity to GB:CAE42096.1; ISBm3, transposase, programmed frameshift join(513927..514499,514502..514870) Brucella suis 1330 1166175 YP_089630.1 CDS BR0514 NC_004310.3 514927 515157 D identified by similarity to OMNI:CC1206; transposase, interruption-C 514927..515157 Brucella suis 1330 1166176 NP_697539.1 CDS BR0517 NC_004310.3 516587 517366 R identified by match to protein family HMM PF00551; formyltransferase complement(516587..517366) Brucella suis 1330 1166179 NP_697540.1 CDS wbkB NC_004310.3 517393 518247 R identified by similarity to GP:4071215; wbkB protein complement(517393..518247) Brucella suis 1330 1166180 NP_697541.1 CDS rfbE NC_004310.3 518244 519002 R identified by similarity to SP:Q56903; match to protein family HMM PF00005; O-antigen export system ATP-binding protein RfbE complement(518244..519002) Brucella suis 1330 1166181 NP_697542.1 CDS rfbD NC_004310.3 518999 519781 R identified by similarity to SP:Q56902; match to protein family HMM PF01061; O-antigen export system permease RfbD complement(518999..519781) Brucella suis 1330 1166182 NP_697543.1 CDS BR0521 NC_004310.3 519796 520899 R identified by similarity to EGAD:15706; match to protein family HMM PF01041; perosamine synthase complement(519796..520899) Brucella suis 1330 1166183 NP_697544.1 CDS gmd NC_004310.3 520907 521995 R identified by similarity to EGAD:11583; match to protein family HMM TIGR01472; GDP-mannose 4,6-dehydratase complement(520907..521995) Brucella suis 1330 1166184 NP_697545.1 CDS BR0523 NC_004310.3 522514 522942 D identified by similarity to GP:4071219; ISBm1, transposase orfA 522514..522942 Brucella suis 1330 1166185 YP_089631.1 CDS BR0524 NC_004310.3 522861 523235 D identified by similarity to GP:4071222; ISBm1, transposase orfB, interruption-N 522861..523235 Brucella suis 1330 1166186 NP_697546.1 CDS BR0526 NC_004310.3 524151 524462 D identified by similarity to EGAD:46813; IS711, transposase orfA 524151..524462 Brucella suis 1330 1166188 NP_697547.1 CDS BR0527 NC_004310.3 524494 524886 D identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 524494..524886 Brucella suis 1330 1166189 YP_089632.1 CDS BR0528 NC_004310.3 524887 525126 D identified by similarity to GP:4071222; ISBm1, transposase orfB, interruption-C 524887..525126 Brucella suis 1330 1166190 NP_697548.1 CDS BR0529 NC_004310.3 525257 526375 D identified by match to protein family HMM PF00534; mannosyltransferase 525257..526375 Brucella suis 1330 1166191 NP_697549.1 CDS BR0530 NC_004310.3 526433 526801 D identified by similarity to EGAD:36179; IS5 family transposase orfA 526433..526801 Brucella suis 1330 1166192 NP_697550.1 CDS BR0531 NC_004310.3 526897 527238 D identified by similarity to GP:482819; IS5 family transposase orfB 526897..527238 Brucella suis 1330 1166193 NP_697551.1 CDS BR0533 NC_004310.3 528047 528475 D identified by similarity to GP:4071219; ISBm1, transposase orfA 528047..528475 Brucella suis 1330 1166195 NP_697552.1 CDS BR0534 NC_004310.3 528394 528810 D identified by similarity to GP:4071222; match to protein family HMM PF01609; ISBm1, transposase orfB 528394..528810 Brucella suis 1330 1166196 NP_697553.1 CDS BR0537 NC_004310.3 529702 531039 D identified by similarity to EGAD:8806; match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880; phosphomannomutase 529702..531039 Brucella suis 1330 1166199 NP_697554.1 CDS BR0538 NC_004310.3 531064 532488 D identified by similarity to EGAD:97081; match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM TIGR01479; mannose-1-phosphate guanylyltransferase 531064..532488 Brucella suis 1330 1166200 NP_697555.1 CDS manA NC_004310.3 532521 533693 D identified by similarity to SP:P29954; mannose-6-phosphate isomerase 532521..533693 Brucella suis 1330 1166201 NP_697556.1 CDS BR0540 NC_004310.3 533776 534885 D identified by similarity to GP:3249553; match to protein family HMM PF00534; group 1 glycosyl transferase 533776..534885 Brucella suis 1330 1166202 NP_697557.1 CDS BR0541 NC_004310.3 535366 535578 R hypothetical protein complement(535366..535578) Brucella suis 1330 1166203 NP_697558.1 CDS rbsA-1 NC_004310.3 535577 537112 D identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein 535577..537112 Brucella suis 1330 1166204 NP_697559.1 CDS rbsC-1 NC_004310.3 537133 538134 D identified by similarity to SP:P36948; match to protein family HMM PF02653; ribose ABC transporter permease 537133..538134 Brucella suis 1330 1166205 NP_697560.1 CDS rbsB-1 NC_004310.3 538213 539175 D identified by similarity to SP:P02926; match to protein family HMM PF00532; ribose ABC transporter periplasmic D-ribose-binding protein 538213..539175 Brucella suis 1330 1166206 NP_697561.1 CDS BR0545 NC_004310.3 539233 540285 D identified by similarity to GP:15075918; hypothetical protein 539233..540285 Brucella suis 1330 1166207 NP_697562.1 CDS BR0546 NC_004310.3 540293 541465 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 540293..541465 Brucella suis 1330 1166208 NP_697563.1 CDS xylA NC_004310.3 541507 542814 R catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase complement(541507..542814) Brucella suis 1330 1166209 NP_697564.1 CDS xylB NC_004310.3 542861 544312 R identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312; xylulokinase complement(542861..544312) Brucella suis 1330 1166210 NP_697565.1 CDS BR0549 NC_004310.3 544345 545376 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcription regulator complement(544345..545376) Brucella suis 1330 1166211 NP_697566.1 CDS BR0550 NC_004310.3 545638 546708 R identified by match to protein family HMM PF00165; AraC family transcriptional regulator complement(545638..546708) Brucella suis 1330 1166212 NP_697567.1 CDS BR0551 NC_004310.3 547080 547187 R hypothetical protein complement(547080..547187) Brucella suis 1330 1166213 NP_697568.1 CDS betB NC_004310.3 547247 548710 R catalyzes the formation of betaine from betaine aldehyde; betaine aldehyde dehydrogenase complement(547247..548710) Brucella suis 1330 1166214 NP_697569.1 CDS betA NC_004310.3 548896 550545 R catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine; choline dehydrogenase complement(548896..550545) Brucella suis 1330 1166215 NP_697570.1 CDS betI NC_004310.3 550548 551144 R HTH-type; bet1; Repressor involved in choline regulation of the bet genes; transcriptional regulator BetI complement(550548..551144) Brucella suis 1330 1166216 NP_697571.1 CDS BR0555 NC_004310.3 551335 552357 D identified by similarity to OMNI:NTL02ML6007; hypothetical protein 551335..552357 Brucella suis 1330 1166217 NP_697572.1 CDS BR0556 NC_004310.3 552402 552872 D identified by match to protein family HMM PF01272; transcription elongation factor GreA domain-containing protein 552402..552872 Brucella suis 1330 1166218 NP_697573.1 CDS BR0557 NC_004310.3 552869 553258 R identified by similarity to EGAD:69439; match to protein family HMM PF05012; match to protein family HMM TIGR01550; death-on-curing family protein complement(552869..553258) Brucella suis 1330 1166219 NP_697574.1 CDS BR0558 NC_004310.3 553255 553485 R identified by match to protein family HMM PF04014; match to protein family HMM TIGR01439; AbrB family transcriptional regulator complement(553255..553485) Brucella suis 1330 1166220 NP_697575.1 CDS BR0559 NC_004310.3 553546 554538 R identified by similarity to GP:15620053; match to protein family HMM PF01544; magnesium/cobalt transporter CorA complement(553546..554538) Brucella suis 1330 1166221 NP_697576.1 CDS BR0560 NC_004310.3 554694 555707 D identified by match to protein family HMM PF00392; GntR family transcriptional regulator 554694..555707 Brucella suis 1330 1166222 NP_697577.1 CDS BR0561 NC_004310.3 555529 556677 D cyanate transport system protein CynX 555529..556677 Brucella suis 1330 1166223 NP_697578.1 CDS BR0562 NC_004310.3 556734 557096 R identified by similarity to GP:15073896; hypothetical protein complement(556734..557096) Brucella suis 1330 1166224 NP_697579.1 CDS BR0563 NC_004310.3 557432 558943 D identified by similarity to OMNI:NTL02ML6012; match to protein family HMM PF05872; hypothetical protein 557432..558943 Brucella suis 1330 1166225 NP_697580.1 CDS BR0564 NC_004310.3 559141 559857 R identified by similarity to GP:15141233; match to protein family HMM PF03734; match to protein family HMM TIGR01409; hypothetical protein complement(559141..559857) Brucella suis 1330 1166226 NP_697581.1 CDS BR0565 NC_004310.3 560160 560813 R identified by similarity to SP:Q51645; match to protein family HMM PF00702; match to protein family HMM TIGR01428; match to protein family HMM TIGR01493; haloacid dehalogenase complement(560160..560813) Brucella suis 1330 1166227 NP_697582.1 CDS BR0566 NC_004310.3 561036 561635 D identified by match to protein family HMM PF00081; match to protein family HMM PF02777; Fe/Mn family superoxide dismutase 561036..561635 Brucella suis 1330 1166228 NP_697583.1 CDS BR0567 NC_004310.3 561681 562256 D hypothetical protein 561681..562256 Brucella suis 1330 1166229 NP_697584.1 CDS ptrB NC_004310.3 562260 564368 R identified by similarity to EGAD:17797; match to protein family HMM PF00326; match to protein family HMM PF02897; oligopeptidase B complement(562260..564368) Brucella suis 1330 1166230 NP_697585.1 CDS BR0569 NC_004310.3 564941 565369 D identified by similarity to EGAD:35422; match to protein family HMM PF05443; Ros/MucR family transcriptional regulator 564941..565369 Brucella suis 1330 1166231 NP_697586.1 CDS BR0570 NC_004310.3 565577 565825 R hypothetical protein complement(565577..565825) Brucella suis 1330 1166232 NP_697587.1 CDS BR0571 NC_004310.3 566070 566525 D hypothetical protein 566070..566525 Brucella suis 1330 1166233 NP_697588.1 CDS BR0572 NC_004310.3 566672 567316 D identified by similarity to GP:15155912; hypothetical protein 566672..567316 Brucella suis 1330 1166234 NP_697589.2 CDS BR0573 NC_004310.3 567428 568651 D catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 567428..568651 Brucella suis 1330 1166235 NP_697590.1 CDS BR0574 NC_004310.3 568692 569117 R identified by similarity to OMNI:NTL02ML6032; match to protein family HMM PF02657; hypothetical protein complement(568692..569117) Brucella suis 1330 1166236 NP_697591.1 CDS BR0575 NC_004310.3 569197 569646 R identified by similarity to SP:Q52968; hypothetical protein complement(569197..569646) Brucella suis 1330 1166237 NP_697592.1 CDS BR0576 NC_004310.3 569832 569951 R hypothetical protein complement(569832..569951) Brucella suis 1330 1166238 NP_697593.1 CDS BR0577 NC_004310.3 569937 571766 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensor histidine kinase 569937..571766 Brucella suis 1330 1166239 NP_697594.1 CDS BR0578 NC_004310.3 571693 572709 D identified by match to protein family HMM PF01471; peptidoglycan-binding protein 571693..572709 Brucella suis 1330 1166240 NP_697595.1 CDS BR0579 NC_004310.3 572723 573070 D hypothetical protein 572723..573070 Brucella suis 1330 1166241 NP_697596.1 CDS BR0580 NC_004310.3 573081 574157 R identified by similarity to GP:15073936; hypothetical protein complement(573081..574157) Brucella suis 1330 1166242 NP_697597.1 CDS BR0581 NC_004310.3 574355 574897 R identified by similarity to GP:15073939; hypothetical protein complement(574355..574897) Brucella suis 1330 1166243 NP_697598.1 CDS BR0582 NC_004310.3 574890 575501 R identified by similarity to OMNI:NTL02ML6040; hypothetical protein complement(574890..575501) Brucella suis 1330 1166244 NP_697599.1 CDS BR0583 NC_004310.3 575508 577664 R identified by match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; 1A family penicillin-binding protein complement(575508..577664) Brucella suis 1330 1166245 NP_697600.1 CDS BR0584 NC_004310.3 578085 578534 D hypothetical protein 578085..578534 Brucella suis 1330 1166246 NP_697601.1 CDS BR0585 NC_004310.3 578578 579732 D terminase large subunit 578578..579732 Brucella suis 1330 1166247 NP_697602.1 CDS BR0586 NC_004310.3 579764 580957 D identified by match to protein family HMM PF04860; match to protein family HMM TIGR01537; HK97 family portal protein 579764..580957 Brucella suis 1330 1166248 NP_697603.1 CDS BR0587 NC_004310.3 580954 581331 D identified by similarity to GP:15155959; hypothetical protein 580954..581331 Brucella suis 1330 1166249 NP_697604.1 CDS BR0588 NC_004310.3 581318 581986 D identified by match to protein family HMM PF04586; match to protein family HMM TIGR01543; protease 581318..581986 Brucella suis 1330 1166250 NP_697605.1 CDS BR0589 NC_004310.3 582008 583282 D identified by match to protein family HMM TIGR01554; HK97 family major capsid protein 582008..583282 Brucella suis 1330 1166251 NP_697606.1 CDS BR0590 NC_004310.3 583447 584013 D identified by similarity to GP:15155962; hypothetical protein 583447..584013 Brucella suis 1330 1166252 NP_697607.1 CDS BR0591 NC_004310.3 584010 584348 D identified by similarity to GP:15155963; match to protein family HMM TIGR01563; hypothetical protein 584010..584348 Brucella suis 1330 1166253 NP_697608.1 CDS BR0592 NC_004310.3 584345 584512 D hypothetical protein 584345..584512 Brucella suis 1330 1166254 NP_697609.1 CDS BR0593 NC_004310.3 584472 584879 D identified by similarity to GP:15155964; hypothetical protein 584472..584879 Brucella suis 1330 1166255 NP_697610.1 CDS BR0594 NC_004310.3 584920 585333 D identified by similarity to OMNI:CC2781; match to protein family HMM TIGR02126; hypothetical protein 584920..585333 Brucella suis 1330 1166256 NP_697611.1 CDS BR0595 NC_004310.3 585336 585671 D identified by similarity to GP:15155967; hypothetical protein 585336..585671 Brucella suis 1330 1166257 NP_697612.1 CDS BR0597 NC_004310.3 585890 586435 D identified by similarity to GP:15155972; hypothetical protein 585890..586435 Brucella suis 1330 1166259 NP_697613.1 CDS BR0598 NC_004310.3 586438 587070 D identified by similarity to GP:15155973; hypothetical protein 586438..587070 Brucella suis 1330 1166260 NP_697614.1 CDS BR0599 NC_004310.3 587067 587942 D identified by similarity to GP:15155974; hypothetical protein 587067..587942 Brucella suis 1330 1166261 NP_697615.1 CDS BR0600 NC_004310.3 587939 588373 D identified by match to protein family HMM PF00877; NLP/P60 family protein 587939..588373 Brucella suis 1330 1166262 NP_697616.1 CDS BR0602 NC_004310.3 592297 592503 D identified by similarity to GP:15155977; hypothetical protein 592297..592503 Brucella suis 1330 1166264 NP_697617.1 CDS BR0603 NC_004310.3 592665 592961 D identified by similarity to OMNI:NTL02ML6060; hypothetical protein 592665..592961 Brucella suis 1330 1166265 NP_697618.1 CDS BR0604 NC_004310.3 593040 593729 D identified by similarity to OMNI:CC2766; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 593040..593729 Brucella suis 1330 1166266 NP_697619.1 CDS BR0605 NC_004310.3 593816 595114 D identified by similarity to GP:14027143; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 593816..595114 Brucella suis 1330 1166267 NP_697620.1 CDS BR0606 NC_004310.3 595175 595660 D identified by similarity to GP:15073947; outer membrane lipoprotein-like protein 595175..595660 Brucella suis 1330 1166268 NP_697621.1 CDS BR0607 NC_004310.3 595761 596900 D cytochrome c-type biogenesis protein 595761..596900 Brucella suis 1330 1166269 NP_697622.1 CDS ccmE NC_004310.3 596897 597394 D CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane; cytochrome c-type biogenesis protein CcmE 596897..597394 Brucella suis 1330 1166270 NP_697623.1 CDS ccmF NC_004310.3 597414 599405 D identified by similarity to EGAD:8346; match to protein family HMM PF01578; match to protein family HMM TIGR00353; cytochrome c-type biogenesis protein CcmF 597414..599405 Brucella suis 1330 1166271 NP_697624.1 CDS ccmh NC_004310.3 599402 599878 D identified by similarity to SP:P45406; match to protein family HMM PF03918; cytochrome c-type biogenesis protein CcmH 599402..599878 Brucella suis 1330 1166272 NP_697625.1 CDS BR0611 NC_004310.3 600020 601561 D identified by similarity to EGAD:21403; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease 600020..601561 Brucella suis 1330 1166273 NP_697626.1 CDS BR0612 NC_004310.3 601655 602362 D identified by match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator 601655..602362 Brucella suis 1330 1166274 NP_697627.1 CDS BR0613 NC_004310.3 602362 603765 D identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase 602362..603765 Brucella suis 1330 1166275 NP_697628.1 CDS glnE NC_004310.3 603888 606839 D catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme; bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase 603888..606839 Brucella suis 1330 1166276 NP_697629.1 CDS BR0615 NC_004310.3 606884 608995 R identified by similarity to GP:15156909; match to protein family HMM PF01755; match to protein family HMM PF04932; hypothetical protein complement(606884..608995) Brucella suis 1330 1166277 NP_697630.1 CDS BR0616 NC_004310.3 609266 611617 R identified by match to protein family HMM PF00512; match to protein family HMM PF00785; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase complement(609266..611617) Brucella suis 1330 1166278 NP_697631.1 CDS pepN NC_004310.3 612008 614659 R identified by similarity to OMNI:NTL02ML6073; match to protein family HMM PF01433; aminopeptidase complement(612008..614659) Brucella suis 1330 1166279 NP_697632.1 CDS BR0618 NC_004310.3 614828 615844 D identified by match to protein family HMM PF00892; hypothetical protein 614828..615844 Brucella suis 1330 1166280 NP_697633.1 CDS BR0619 NC_004310.3 615849 617105 R identified by match to protein family HMM PF00083; major facilitator family transporter complement(615849..617105) Brucella suis 1330 1166281 NP_697634.1 CDS BR0620 NC_004310.3 617267 618139 R identified by match to protein family HMM PF03167; match to protein family HMM TIGR00758; phage SPO1 DNA polymerase-like protein complement(617267..618139) Brucella suis 1330 1166282 NP_697635.1 CDS BR0621 NC_004310.3 618528 620219 D identified by similarity to EGAD:4120; match to protein family HMM PF05187; electron transfer flavoprotein-ubiquinone oxidoreductase 618528..620219 Brucella suis 1330 1166283 NP_697636.1 CDS BR0622 NC_004310.3 620335 621303 R identified by similarity to OMNI:NTL02ML6082; match to protein family HMM PF03372; AP endonuclease domain-containing protein complement(620335..621303) Brucella suis 1330 1166284 NP_697637.1 CDS amn NC_004310.3 621464 622966 R Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile; AMP nucleosidase complement(621464..622966) Brucella suis 1330 1166285 NP_697638.1 CDS BR0624 NC_004310.3 623019 623177 D hypothetical protein 623019..623177 Brucella suis 1330 1166286 NP_697639.1 CDS BR0625 NC_004310.3 623159 623455 D hypothetical protein 623159..623455 Brucella suis 1330 1166287 NP_697640.1 CDS BR0626 NC_004310.3 623533 624243 D identified by similarity to OMNI:CC2434; match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase 623533..624243 Brucella suis 1330 1166288 NP_697641.1 CDS BR0627 NC_004310.3 624302 624649 R identified by similarity to GP:15073978; hypothetical protein complement(624302..624649) Brucella suis 1330 1166289 NP_697642.1 CDS BR0628 NC_004310.3 624646 624936 R hypothetical protein complement(624646..624936) Brucella suis 1330 1166290 NP_697643.1 CDS BR0629 NC_004310.3 625155 625412 D identified by similarity to OMNI:NTL02ML6087; hypothetical protein 625155..625412 Brucella suis 1330 1166291 NP_697644.1 CDS BR0630 NC_004310.3 625472 626245 R identified by similarity to OMNI:VC0940; match to protein family HMM PF02588; hypothetical protein complement(625472..626245) Brucella suis 1330 1166292 NP_697645.1 CDS BR0631 NC_004310.3 626237 626350 D hypothetical protein 626237..626350 Brucella suis 1330 1166293 NP_697646.1 CDS BR0632 NC_004310.3 626509 626604 D hypothetical protein 626509..626604 Brucella suis 1330 1166294 NP_697647.1 CDS BR0633 NC_004310.3 626898 627548 D identified by similarity to OMNI:NTL02ML2997; hypothetical protein 626898..627548 Brucella suis 1330 1166295 NP_697648.1 CDS BR0634 NC_004310.3 627593 627967 R identified by similarity to OMNI:NTL02ML6597; match to protein family HMM PF04241; hypothetical protein complement(627593..627967) Brucella suis 1330 1166296 NP_697649.1 CDS BR0635 NC_004310.3 627985 629118 R catalyzes the formation of histidinol phosphate and 2-oxoglutarate from glutamate and imidazole acetol-phosphate; histidinol-phosphate aminotransferase complement(627985..629118) Brucella suis 1330 1166297 NP_697650.1 CDS BR0636 NC_004310.3 629481 630407 R identified by match to protein family HMM PF00589; match to protein family HMM PF02899; phage integrase site specific recombinase complement(629481..630407) Brucella suis 1330 1166298 NP_697651.1 CDS omp2a NC_004310.3 630681 631784 R identified by similarity to GP:841493; match to protein family HMM PF02530; porin complement(630681..631784) Brucella suis 1330 1166299 NP_697652.1 CDS BR0638 NC_004310.3 632438 632545 R hypothetical protein complement(632438..632545) Brucella suis 1330 1166301 NP_697653.1 CDS omp2b NC_004310.3 632585 633712 D identified by similarity to GP:841494; match to protein family HMM PF02530; porin 632585..633712 Brucella suis 1330 1166302 NP_697654.1 CDS BR0640 NC_004310.3 633856 634497 D hypothetical protein 633856..634497 Brucella suis 1330 1166303 NP_697655.1 CDS BR0641 NC_004310.3 634547 634747 R hypothetical protein complement(634547..634747) Brucella suis 1330 1166304 NP_697656.1 CDS BR0642 NC_004310.3 634797 635471 D identified by similarity to EGAD:126787; hypothetical protein 634797..635471 Brucella suis 1330 1166305 NP_697657.1 CDS BR0643 NC_004310.3 635534 637492 R identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein complement(635534..637492) Brucella suis 1330 1166306 NP_697658.1 CDS BR0644 NC_004310.3 637515 637679 D hypothetical protein 637515..637679 Brucella suis 1330 1166307 NP_697659.1 CDS BR0645 NC_004310.3 637762 637854 D hypothetical protein 637762..637854 Brucella suis 1330 1166308 NP_697660.1 CDS dapA NC_004310.3 638067 638948 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 638067..638948 Brucella suis 1330 1166309 NP_697661.1 CDS smpB NC_004310.3 639039 639515 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 639039..639515 Brucella suis 1330 1166310 NP_697662.1 CDS BR0648 NC_004310.3 639751 640422 R identified by match to protein family HMM PF03167; phage SPO1 DNA polymerase-like protein complement(639751..640422) Brucella suis 1330 1166311 NP_697663.1 CDS BR0649 NC_004310.3 640453 641028 R identified by match to protein family HMM PF01936; hypothetical protein complement(640453..641028) Brucella suis 1330 1166312 NP_697664.1 CDS BR0650 NC_004310.3 641228 641383 R hypothetical protein complement(641228..641383) Brucella suis 1330 1166313 NP_697665.1 CDS rpoZ NC_004310.3 641425 641826 D Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 641425..641826 Brucella suis 1330 1166314 NP_697666.1 CDS BR0652 NC_004310.3 642067 644319 D identified by match to protein family HMM PF01842; match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691; RelA/SpoT family protein 642067..644319 Brucella suis 1330 1166315 NP_697667.1 CDS pyrE NC_004310.3 644327 644905 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 644327..644905 Brucella suis 1330 1166316 NP_697668.1 CDS BR0654 NC_004310.3 645074 645820 D identified by match to protein family HMM PF00027; match to protein family HMM PF00325; Crp/Fnr family transcriptional regulator 645074..645820 Brucella suis 1330 1166317 NP_697669.1 CDS hemN-1 NC_004310.3 646201 647535 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase 646201..647535 Brucella suis 1330 1166318 NP_697670.1 CDS fsr NC_004310.3 647719 648930 R identified by similarity to EGAD:36955; fosmidomycin resistance protein complement(647719..648930) Brucella suis 1330 1166319 NP_697671.1 CDS BR0657 NC_004310.3 649182 649964 D identified by match to protein family HMM PF00165; match to protein family HMM PF02311; AraC family transcriptional regulator 649182..649964 Brucella suis 1330 1166320 NP_697672.1 CDS BR0658 NC_004310.3 650017 650589 D identified by similarity to GP:14027200; hypothetical protein 650017..650589 Brucella suis 1330 1166321 NP_697673.1 CDS acpS NC_004310.3 650586 650990 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 650586..650990 Brucella suis 1330 1166322 NP_697674.1 CDS BR0660 NC_004310.3 651101 651883 D identified by similarity to OMNI:NTL02ML6121; match to protein family HMM PF00461; signal peptidase I 651101..651883 Brucella suis 1330 1166323 NP_697675.1 CDS rncS NC_004310.3 651852 652589 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 651852..652589 Brucella suis 1330 1166324 NP_697676.1 CDS BR0662 NC_004310.3 652632 652730 D hypothetical protein 652632..652730 Brucella suis 1330 1166325 NP_697677.1 CDS era NC_004310.3 652734 653669 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 652734..653669 Brucella suis 1330 1166326 NP_697678.1 CDS recO NC_004310.3 653696 654439 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 653696..654439 Brucella suis 1330 1166327 NP_697679.1 CDS BR0665 NC_004310.3 654417 654926 R identified by similarity to GP:15074034; hypothetical protein complement(654417..654926) Brucella suis 1330 1166328 NP_697680.1 CDS BR0666 NC_004310.3 654923 655543 R identified by similarity to OMNI:NTL02ML6141; hypothetical protein complement(654923..655543) Brucella suis 1330 1166329 NP_697681.1 CDS BR0667 NC_004310.3 655543 656406 R identified by match to protein family HMM PF01571; glycine cleavage system protein T complement(655543..656406) Brucella suis 1330 1166330 NP_697682.1 CDS pyrC-1 NC_004310.3 656492 657826 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 656492..657826 Brucella suis 1330 1166331 NP_697683.1 CDS BR0669 NC_004310.3 657875 658639 R identified by similarity to GP:14027225; hypothetical protein complement(657875..658639) Brucella suis 1330 1166332 NP_697684.1 CDS BR0670 NC_004310.3 658688 658954 R identified by similarity to GP:15074038; hypothetical protein complement(658688..658954) Brucella suis 1330 1166333 NP_697685.1 CDS BR0671 NC_004310.3 659111 659494 R identified by similarity to OMNI:NTL02ML6146; hypothetical protein complement(659111..659494) Brucella suis 1330 1166334 NP_697686.1 CDS BR0672 NC_004310.3 659574 660017 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(659574..660017) Brucella suis 1330 1166335 NP_697687.1 CDS BR0673 NC_004310.3 660103 660882 D identified by similarity to EGAD:107474; match to protein family HMM PF02586; hypothetical protein 660103..660882 Brucella suis 1330 1166336 NP_697688.1 CDS BR0674 NC_004310.3 660937 661551 D identified by match to protein family HMM PF01810; amino acid transporter LysE 660937..661551 Brucella suis 1330 1166337 NP_697689.1 CDS BR0675 NC_004310.3 661528 661695 R hypothetical protein complement(661528..661695) Brucella suis 1330 1166338 NP_697690.1 CDS BR0676 NC_004310.3 661821 661943 D hypothetical protein 661821..661943 Brucella suis 1330 1166339 NP_697691.1 CDS cysS NC_004310.3 662062 663582 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 662062..663582 Brucella suis 1330 1166340 NP_697692.1 CDS BR0678 NC_004310.3 663601 663735 D hypothetical protein 663601..663735 Brucella suis 1330 1166341 NP_697693.1 CDS BR0679 NC_004310.3 663735 665348 D catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA; alpha-isopropylmalate/homocitrate synthase transferase 663735..665348 Brucella suis 1330 1166342 NP_697694.1 CDS rarD NC_004310.3 665595 666515 D identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688; rarD protein 665595..666515 Brucella suis 1330 1166343 NP_697695.1 CDS BR0681 NC_004310.3 666648 668381 D identified by match to protein family HMM PF01551; M24/M37 family peptidase 666648..668381 Brucella suis 1330 1166344 NP_697696.1 CDS ksgA NC_004310.3 668449 669279 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(668449..669279) Brucella suis 1330 1166345 NP_697697.1 CDS pdxA NC_004310.3 669276 670307 R catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate); 4-hydroxythreonine-4-phosphate dehydrogenase complement(669276..670307) Brucella suis 1330 1166346 NP_697698.1 CDS BR0684 NC_004310.3 670372 671328 R peptidyl-prolyl cis-trans isomerase complement(670372..671328) Brucella suis 1330 1166347 NP_697699.1 CDS BR0685 NC_004310.3 671639 674017 R identified by similarity to EGAD:7471; match to protein family HMM PF04453; organic solvent tolerance complement(671639..674017) Brucella suis 1330 1166348 NP_697700.1 CDS BR0686 NC_004310.3 674038 675126 R identified by similarity to OMNI:NTL02ML6205; match to protein family HMM PF03739; hypothetical protein complement(674038..675126) Brucella suis 1330 1166349 NP_697701.1 CDS BR0687 NC_004310.3 675123 676331 R identified by match to protein family HMM PF03739; hypothetical protein complement(675123..676331) Brucella suis 1330 1166350 NP_697702.1 CDS BR0688 NC_004310.3 676504 676722 R hypothetical protein complement(676504..676722) Brucella suis 1330 1166351 NP_697703.1 CDS BR0689 NC_004310.3 676741 678234 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 676741..678234 Brucella suis 1330 1166352 NP_697704.1 CDS BR0690 NC_004310.3 678306 678755 D binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB; DNA polymerase III subunit chi 678306..678755 Brucella suis 1330 1166353 NP_697705.1 CDS BR0691 NC_004310.3 678755 679318 D identified by similarity to OMNI:NTL02ML6220; hypothetical protein 678755..679318 Brucella suis 1330 1166354 NP_697706.1 CDS BR0692 NC_004310.3 679395 681278 R identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(679395..681278) Brucella suis 1330 1166355 NP_697707.1 CDS BR0693 NC_004310.3 681321 681833 R identified by similarity to OMNI:NTL02ML6242; match to protein family HMM PF05163; hypothetical protein complement(681321..681833) Brucella suis 1330 1166356 NP_697708.1 CDS ndk NC_004310.3 682062 682484 D catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 682062..682484 Brucella suis 1330 1166357 NP_697709.1 CDS BR0695 NC_004310.3 682593 683396 R identified by similarity to GP:14027320; match to protein family HMM PF03724; hypothetical protein complement(682593..683396) Brucella suis 1330 1166358 NP_697710.1 CDS moaE NC_004310.3 683632 684123 R identified by similarity to SP:P30749; match to protein family HMM PF02391; molybdopterin converting factor subunit 2 complement(683632..684123) Brucella suis 1330 1166359 NP_697711.1 CDS moaD NC_004310.3 684125 684382 R identified by match to protein family HMM PF02597; match to protein family HMM TIGR01682; molybdopterin converting factor subunit 1 complement(684125..684382) Brucella suis 1330 1166360 NP_697712.1 CDS pgsA NC_004310.3 684387 684971 R identified by similarity to SP:P06978; match to protein family HMM PF01066; match to protein family HMM TIGR00560; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(684387..684971) Brucella suis 1330 1166361 NP_697713.2 CDS uvrC NC_004310.3 685090 687162 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C complement(685090..687162) Brucella suis 1330 1166362 NP_697714.1 CDS BR0700 NC_004310.3 687162 687917 R identified by match to protein family HMM PF00106; short chain dehydrogenase complement(687162..687917) Brucella suis 1330 1166363 NP_697715.1 CDS omp25 NC_004310.3 688319 688960 D identified by similarity to SP:Q45689; match to protein family HMM PF01389; outer-membrane protein Omp25 688319..688960 Brucella suis 1330 1166364 NP_697716.1 CDS BR0702 NC_004310.3 689057 689656 R identified by similarity to OMNI:CC0147; match to protein family HMM PF02798; glutathione S-transferase complement(689057..689656) Brucella suis 1330 1166365 NP_697717.1 CDS BR0703 NC_004310.3 689711 690400 R identified by match to protein family HMM PF00445; ribonuclease T2 family protein complement(689711..690400) Brucella suis 1330 1166366 NP_697718.1 CDS BR0704 NC_004310.3 690413 690883 R identified by similarity to OMNI:NTL02ML6225; hypothetical protein complement(690413..690883) Brucella suis 1330 1166367 NP_697719.1 CDS BR0705 NC_004310.3 690966 691838 R identified by similarity to OMNI:NTL02ML6221; match to protein family HMM PF04378; hypothetical protein complement(690966..691838) Brucella suis 1330 1166368 NP_697720.1 CDS BR0706 NC_004310.3 691994 692839 D identified by similarity to GP:15074178; match to protein family HMM PF00892; hypothetical protein 691994..692839 Brucella suis 1330 1166369 NP_697721.1 CDS BR0707 NC_004310.3 692917 695043 D identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; molybdopterin-binding oxidoreductase 692917..695043 Brucella suis 1330 1166370 NP_697722.1 CDS BR0708 NC_004310.3 695270 695794 R identified by similarity to OMNI:NTL02ML2404; hypothetical protein complement(695270..695794) Brucella suis 1330 1166371 NP_697723.2 CDS purN NC_004310.3 695970 696587 R glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase complement(695970..696587) Brucella suis 1330 1166372 NP_697724.1 CDS purM NC_004310.3 696584 697663 R catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase complement(696584..697663) Brucella suis 1330 1166373 NP_697725.1 CDS BR0711 NC_004310.3 697705 697884 R hypothetical protein complement(697705..697884) Brucella suis 1330 1166374 NP_697726.1 CDS BR0712 NC_004310.3 698012 698113 R hypothetical protein complement(698012..698113) Brucella suis 1330 1166375 NP_697727.1 CDS BR0713 NC_004310.3 698153 699301 D identified by match to protein family HMM PF01594; permease 698153..699301 Brucella suis 1330 1166376 NP_697728.1 CDS BR0714 NC_004310.3 699341 700036 D identified by similarity to GP:14027358; hypothetical protein 699341..700036 Brucella suis 1330 1166377 NP_697729.1 CDS BR0715 NC_004310.3 700033 700902 D epimerase 700033..700902 Brucella suis 1330 1166378 NP_697730.1 CDS BR0716 NC_004310.3 700899 701684 R hypothetical protein complement(700899..701684) Brucella suis 1330 1166379 NP_697731.1 CDS BR0717 NC_004310.3 701757 702461 R identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase complement(701757..702461) Brucella suis 1330 1166380 NP_697732.1 CDS BR0718 NC_004310.3 702623 702838 R hypothetical protein complement(702623..702838) Brucella suis 1330 1166381 NP_697733.1 CDS BR0719 NC_004310.3 702852 703007 D hypothetical protein 702852..703007 Brucella suis 1330 1166382 NP_697734.1 CDS lldP NC_004310.3 703160 704833 R identified by similarity to SP:P33231; match to protein family HMM PF02652; match to protein family HMM TIGR00795; L-lactate permease complement(703160..704833) Brucella suis 1330 1166383 NP_697735.1 CDS BR0721 NC_004310.3 705367 705672 D identified by similarity to GP:15074650; match to protein family HMM PF04800; oxidoreductase 705367..705672 Brucella suis 1330 1166385 NP_697736.1 CDS BR0722 NC_004310.3 706238 706828 D hypothetical protein 706238..706828 Brucella suis 1330 1166387 NP_697737.1 CDS BR0723 NC_004310.3 707049 707660 R identified by match to protein family HMM PF00929; exonuclease complement(707049..707660) Brucella suis 1330 1166388 NP_697738.1 CDS BR0724 NC_004310.3 707985 708503 R identified by similarity to EGAD:40466; adenylate kinase complement(707985..708503) Brucella suis 1330 1166389 NP_697739.1 CDS BR0725 NC_004310.3 708527 710062 R identified by match to protein family HMM PF00583; acetyltransferase complement(708527..710062) Brucella suis 1330 1166390 NP_697740.1 CDS BR0726 NC_004310.3 710037 710831 R identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator complement(710037..710831) Brucella suis 1330 1166391 NP_697741.1 CDS BR0727 NC_004310.3 710856 711275 R hypothetical protein complement(710856..711275) Brucella suis 1330 1166392 NP_697742.1 CDS BR0728 NC_004310.3 711655 712551 D hypothetical protein 711655..712551 Brucella suis 1330 1166393 NP_697743.1 CDS BR0729 NC_004310.3 712551 714665 D identified by match to protein family HMM PF00665; transposase 712551..714665 Brucella suis 1330 1166394 NP_697744.1 CDS BR0730 NC_004310.3 714658 715608 D identified by similarity to GP:11071899; transposition protein 714658..715608 Brucella suis 1330 1166395 NP_697745.1 CDS BR0731 NC_004310.3 715605 717182 D hypothetical protein 715605..717182 Brucella suis 1330 1166396 NP_697746.1 CDS BR0732 NC_004310.3 717481 717678 R hypothetical protein complement(717481..717678) Brucella suis 1330 1166397 NP_697747.1 CDS BR0733 NC_004310.3 717919 719226 D hypothetical protein 717919..719226 Brucella suis 1330 1166398 NP_697748.1 CDS BR0734 NC_004310.3 719680 721053 D hypothetical protein 719680..721053 Brucella suis 1330 1166399 NP_697749.1 CDS BR0735 NC_004310.3 721187 722020 D hypothetical protein 721187..722020 Brucella suis 1330 1166400 NP_697750.1 CDS BR0736 NC_004310.3 722404 722916 R identified by similarity to GP:15162152; hypothetical protein complement(722404..722916) Brucella suis 1330 1166401 NP_697751.1 CDS BR0737 NC_004310.3 723076 723324 R lipoprotein complement(723076..723324) Brucella suis 1330 1166402 NP_697752.1 CDS BR0738 NC_004310.3 723427 723582 R hypothetical protein complement(723427..723582) Brucella suis 1330 1166403 NP_697753.1 CDS metC NC_004310.3 723569 724738 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase complement(723569..724738) Brucella suis 1330 1166404 NP_697754.1 CDS BR0740 NC_004310.3 724949 725716 D identified by match to protein family HMM PF01569; PAP2 family protein 724949..725716 Brucella suis 1330 1166405 NP_697755.1 CDS BR0741 NC_004310.3 726172 727203 D identified by similarity to EGAD:35379; match to protein family HMM PF00497; match to protein family HMM TIGR01096; amino acid ABC transporter substrate-binding protein 726172..727203 Brucella suis 1330 1166406 NP_697756.1 CDS BR0742 NC_004310.3 727237 727464 D hypothetical protein 727237..727464 Brucella suis 1330 1166407 NP_697757.1 CDS BR0743 NC_004310.3 727500 728693 D identified by similarity to EGAD:35466; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 727500..728693 Brucella suis 1330 1166408 NP_697758.1 CDS BR0744 NC_004310.3 728696 729853 D identified by similarity to SP:P45768; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 728696..729853 Brucella suis 1330 1166409 NP_697759.1 CDS BR0745 NC_004310.3 729934 730683 D identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 729934..730683 Brucella suis 1330 1166410 NP_697760.1 CDS BR0746 NC_004310.3 730731 731936 R catalyzes the formation of catechol from salicylate; salicylate hydroxylase complement(730731..731936) Brucella suis 1330 1166411 NP_697761.1 CDS BR0747 NC_004310.3 731966 732220 R identified by similarity to GP:15074414; hypothetical protein complement(731966..732220) Brucella suis 1330 1166412 NP_697762.1 CDS ppk NC_004310.3 732506 734746 D catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate; polyphosphate kinase 732506..734746 Brucella suis 1330 1166413 NP_697763.1 CDS BR0749 NC_004310.3 734743 736281 D identified by match to protein family HMM PF02541; Ppx/GppA phosphatase 734743..736281 Brucella suis 1330 1166414 NP_697764.1 CDS rnd NC_004310.3 736411 737568 R identified by similarity to GP:17739552; match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388; ribonuclease D complement(736411..737568) Brucella suis 1330 1166415 NP_697765.1 CDS aspS NC_004310.3 737795 739582 D catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 737795..739582 Brucella suis 1330 1166416 NP_697766.1 CDS BR0752 NC_004310.3 739666 740862 R identified by similarity to GP:14027664; hypothetical protein complement(739666..740862) Brucella suis 1330 1166417 NP_697767.1 CDS BR0753 NC_004310.3 740917 741156 D hypothetical protein 740917..741156 Brucella suis 1330 1166418 NP_697768.1 CDS parC NC_004310.3 741262 743574 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 741262..743574 Brucella suis 1330 1166419 NP_697769.1 CDS BR0755 NC_004310.3 743753 744502 R Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate; arginyl-tRNA-protein transferase complement(743753..744502) Brucella suis 1330 1166420 NP_697770.1 CDS BR0756 NC_004310.3 744623 745093 R identified by similarity to OMNI:NTL02ML6587; hypothetical protein complement(744623..745093) Brucella suis 1330 1166421 NP_697771.1 CDS hemB NC_004310.3 745240 746277 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(745240..746277) Brucella suis 1330 1166422 NP_697772.1 CDS BR0758 NC_004310.3 746445 747494 D catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA; 3-hydroxyisobutyryl-CoA hydrolase 746445..747494 Brucella suis 1330 1166423 NP_697773.1 CDS BR0759 NC_004310.3 747508 747942 D identified by similarity to OMNI:NTL02ML6608; hypothetical protein 747508..747942 Brucella suis 1330 1166424 NP_697774.1 CDS BR0760 NC_004310.3 748173 748772 D identified by match to protein family HMM PF01047; MarR family transcriptional regulator 748173..748772 Brucella suis 1330 1166425 NP_697775.1 CDS BR0761 NC_004310.3 748859 748999 R hypothetical protein complement(748859..748999) Brucella suis 1330 1166426 NP_697776.1 CDS BR0762 NC_004310.3 749134 750435 D identified by match to protein family HMM PF01471; match to protein family HMM TIGR01409; peptidoglycan-binding protein 749134..750435 Brucella suis 1330 1166427 NP_697777.1 CDS BR0763 NC_004310.3 750441 750536 R hypothetical protein complement(750441..750536) Brucella suis 1330 1166428 NP_697778.1 CDS BR0764 NC_004310.3 750528 750662 D hypothetical protein 750528..750662 Brucella suis 1330 1166429 NP_697779.1 CDS glyA NC_004310.3 750666 751982 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 750666..751982 Brucella suis 1330 1166430 NP_697780.1 CDS nrdR NC_004310.3 752224 752700 D identified by similarity to GP:14027700; match to protein family HMM PF03477; match to protein family HMM TIGR00244; transcriptional regulator NrdR 752224..752700 Brucella suis 1330 1166431 NP_697781.1 CDS ribD NC_004310.3 752702 753823 D identified by match to protein family HMM PF00383; match to protein family HMM PF01872; match to protein family HMM TIGR00326; riboflavin biosynthesis protein RibD 752702..753823 Brucella suis 1330 1166432 NP_697782.1 CDS ribE NC_004310.3 753823 754431 D catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 753823..754431 Brucella suis 1330 1166433 NP_697783.1 CDS ribH NC_004310.3 754514 754987 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 754514..754987 Brucella suis 1330 1166434 NP_697784.1 CDS nusB NC_004310.3 754993 755508 D Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 754993..755508 Brucella suis 1330 1166435 NP_697785.1 CDS hppA NC_004310.3 755959 758115 D pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient; membrane-bound proton-translocating pyrophosphatase 755959..758115 Brucella suis 1330 1166436 NP_697786.1 CDS BR0772 NC_004310.3 758187 758705 R identified by similarity to GP:15074151; match to protein family HMM PF04355; hypothetical protein complement(758187..758705) Brucella suis 1330 1166437 NP_697787.1 CDS BR0773 NC_004310.3 758795 759349 D identified by similarity to OMNI:NTL02ML6629; match to protein family HMM PF03981; hypothetical protein 758795..759349 Brucella suis 1330 1166438 NP_697788.1 CDS BR0774 NC_004310.3 759469 760026 D identified by similarity to GP:15074153; hypothetical protein 759469..760026 Brucella suis 1330 1166439 NP_697789.1 CDS BR0775 NC_004310.3 760074 760169 R hypothetical protein complement(760074..760169) Brucella suis 1330 1166440 NP_697790.1 CDS plsX NC_004310.3 760144 761184 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 760144..761184 Brucella suis 1330 1166441 NP_697791.1 CDS fabH NC_004310.3 761432 762403 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 761432..762403 Brucella suis 1330 1166442 NP_697792.1 CDS ihfA NC_004310.3 762522 762845 D This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 762522..762845 Brucella suis 1330 1166443 NP_697793.1 CDS BR0779 NC_004310.3 763379 763921 D identified by similarity to OMNI:NTL02ML6634; hypothetical protein 763379..763921 Brucella suis 1330 1166444 NP_697794.1 CDS sugE NC_004310.3 763971 764288 R identified by similarity to SP:P30743; match to protein family HMM PF00893; sugE protein complement(763971..764288) Brucella suis 1330 1166445 NP_697795.1 CDS BR0781 NC_004310.3 764634 766172 R identified by match to protein family HMM PF02397; sugar transferase complement(764634..766172) Brucella suis 1330 1166447 NP_697796.1 CDS BR0782 NC_004310.3 766302 766517 R identified by similarity to GP:14027725; hypothetical protein complement(766302..766517) Brucella suis 1330 1166448 NP_697797.1 CDS BR0783 NC_004310.3 766526 767113 R identified by similarity to EGAD:19692; match to protein family HMM PF02563; capsule polysaccharide export protein complement(766526..767113) Brucella suis 1330 1166449 NP_697798.1 CDS BR0784 NC_004310.3 767096 767194 D hypothetical protein 767096..767194 Brucella suis 1330 1166450 NP_697799.1 CDS BR0785 NC_004310.3 767237 767899 D hypothetical protein 767237..767899 Brucella suis 1330 1166451 NP_697800.1 CDS BR0786 NC_004310.3 767967 768185 R identified by similarity to OMNI:NTL02ML6654; hypothetical protein complement(767967..768185) Brucella suis 1330 1166452 NP_697801.1 CDS BR0787 NC_004310.3 768537 769613 D identified by match to protein family HMM PF02628; cytochrome c oxidase assembly protein 768537..769613 Brucella suis 1330 1166453 NP_697802.1 CDS argC NC_004310.3 769766 770698 R catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; N-acetyl-gamma-glutamyl-phosphate reductase complement(769766..770698) Brucella suis 1330 1166454 NP_697803.1 CDS BR0789 NC_004310.3 770788 771738 R catalyzes the formation of putrescine from agmatine; agmatinase complement(770788..771738) Brucella suis 1330 1166455 NP_697804.1 CDS rpsI NC_004310.3 771829 772305 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(771829..772305) Brucella suis 1330 1166456 NP_697805.1 CDS rplM NC_004310.3 772308 772772 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(772308..772772) Brucella suis 1330 1166457 NP_697806.1 CDS BR0792 NC_004310.3 773008 773454 R identified by similarity to OMNI:NTL02ML6663; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein complement(773008..773454) Brucella suis 1330 1166458 NP_697807.1 CDS BR0793 NC_004310.3 773688 774971 D catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; O-acetylhomoserine aminocarboxypropyltransferase 773688..774971 Brucella suis 1330 1166459 NP_697808.1 CDS BR0794 NC_004310.3 774834 775496 R hypothetical protein complement(774834..775496) Brucella suis 1330 1166460 NP_697809.1 CDS BR0795 NC_004310.3 775673 775804 D hypothetical protein 775673..775804 Brucella suis 1330 1166461 NP_697810.1 CDS BR0796 NC_004310.3 776058 776567 D hypothetical protein 776058..776567 Brucella suis 1330 1166462 NP_697811.1 CDS BR0797 NC_004310.3 776564 776959 D hypothetical protein 776564..776959 Brucella suis 1330 1166463 NP_697812.1 CDS BR0798 NC_004310.3 777013 777348 D hypothetical protein 777013..777348 Brucella suis 1330 1166464 NP_697813.1 CDS BR0799 NC_004310.3 777405 777806 R hypothetical protein complement(777405..777806) Brucella suis 1330 1166465 NP_697814.1 CDS BR0800 NC_004310.3 778103 778285 D hypothetical protein 778103..778285 Brucella suis 1330 1166467 NP_697815.1 CDS BR0801 NC_004310.3 778669 778872 R hypothetical protein complement(778669..778872) Brucella suis 1330 1166469 NP_697816.1 CDS nuoA NC_004310.3 779380 779745 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit A 779380..779745 Brucella suis 1330 1166470 NP_697817.1 CDS nuoB NC_004310.3 779736 780317 D The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 779736..780317 Brucella suis 1330 1166471 NP_697818.1 CDS nuoC NC_004310.3 780430 781038 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit C 780430..781038 Brucella suis 1330 1166472 NP_697819.1 CDS nuoD NC_004310.3 781056 782246 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 781056..782246 Brucella suis 1330 1166473 NP_697820.1 CDS nuoE NC_004310.3 782246 782959 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 782246..782959 Brucella suis 1330 1166474 NP_697821.1 CDS nuoF NC_004310.3 782963 784270 D part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 782963..784270 Brucella suis 1330 1166475 NP_697822.1 CDS nuoG NC_004310.3 784405 786489 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 784405..786489 Brucella suis 1330 1166476 NP_697823.1 CDS nuoH NC_004310.3 786509 787552 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 786509..787552 Brucella suis 1330 1166477 NP_697824.1 CDS nuoI NC_004310.3 787565 788056 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 787565..788056 Brucella suis 1330 1166478 NP_697825.1 CDS nuoJ NC_004310.3 788230 788847 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit J 788230..788847 Brucella suis 1330 1166479 NP_697826.1 CDS nuoK NC_004310.3 788858 789166 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit K 788858..789166 Brucella suis 1330 1166480 NP_697827.1 CDS nuoL NC_004310.3 789174 791159 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH dehydrogenase subunit L 789174..791159 Brucella suis 1330 1166481 NP_697828.1 CDS nuoM NC_004310.3 791159 792667 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit M 791159..792667 Brucella suis 1330 1166482 NP_697829.1 CDS nuoN NC_004310.3 792689 794125 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit N 792689..794125 Brucella suis 1330 1166483 NP_697830.1 CDS BR0816 NC_004310.3 794151 794948 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 794151..794948 Brucella suis 1330 1166484 NP_697831.1 CDS BR0817 NC_004310.3 795142 796818 D identified by match to protein family HMM PF00753; metallo-beta-lactamase 795142..796818 Brucella suis 1330 1166485 NP_697832.1 CDS BR0818 NC_004310.3 796858 797262 D identified by match to protein family HMM PF00903; glyoxalase 796858..797262 Brucella suis 1330 1166486 NP_697833.1 CDS BR0819 NC_004310.3 797265 797534 D identified by similarity to OMNI:NTL02ML1060; hypothetical protein 797265..797534 Brucella suis 1330 1166487 NP_697834.1 CDS BR0820 NC_004310.3 797892 798032 D hypothetical protein 797892..798032 Brucella suis 1330 1166488 NP_697835.1 CDS BR0821 NC_004310.3 798063 798155 D hypothetical protein 798063..798155 Brucella suis 1330 1166489 NP_697836.1 CDS proS NC_004310.3 798382 799710 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 798382..799710 Brucella suis 1330 1166490 NP_697837.1 CDS BR0823 NC_004310.3 799752 801020 D identified by match to protein family HMM PF02687; ABC transporter permease 799752..801020 Brucella suis 1330 1166491 NP_697838.1 CDS lolD NC_004310.3 801020 801703 D identified by similarity to SP:P75957; match to protein family HMM PF00005; lipoprotein releasing system ATP-binding protein LolD 801020..801703 Brucella suis 1330 1166492 NP_697839.1 CDS dnaE NC_004310.3 802362 805853 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; DNA polymerase III subunit alpha 802362..805853 Brucella suis 1330 1166493 NP_697840.1 CDS BR0826 NC_004310.3 805894 806091 D identified by similarity to OMNI:NTL02ML0034; hypothetical protein 805894..806091 Brucella suis 1330 1166494 NP_697841.1 CDS BR0827 NC_004310.3 806136 806549 R hypothetical protein complement(806136..806549) Brucella suis 1330 1166495 NP_697842.1 CDS BR0828 NC_004310.3 806821 807792 R identified by similarity to OMNI:NTL02ML1990; hypothetical protein complement(806821..807792) Brucella suis 1330 1166496 NP_697843.1 CDS BR0829 NC_004310.3 807791 807955 D hypothetical protein 807791..807955 Brucella suis 1330 1166497 NP_697844.1 CDS rpsD NC_004310.3 808127 808744 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 808127..808744 Brucella suis 1330 1166498 NP_697845.1 CDS BR0831 NC_004310.3 809253 810134 D TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs; C32 tRNA thiolase 809253..810134 Brucella suis 1330 1166499 NP_697846.1 CDS BR0832 NC_004310.3 810121 810948 D identified by match to protein family HMM PF00459; inositol monophosphatase 810121..810948 Brucella suis 1330 1166500 NP_697847.1 CDS BR0833 NC_004310.3 811163 812428 R identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter complement(811163..812428) Brucella suis 1330 1166501 NP_697848.1 CDS BR0834 NC_004310.3 812412 812612 D hypothetical protein 812412..812612 Brucella suis 1330 1166502 NP_697849.1 CDS BR0835 NC_004310.3 812699 813091 R identified by match to protein family HMM TIGR00365; glutaredoxin-like protein complement(812699..813091) Brucella suis 1330 1166503 NP_697850.1 CDS BR0836 NC_004310.3 813216 813449 R identified by match to protein family HMM PF01722; bolA-like protein complement(813216..813449) Brucella suis 1330 1166504 NP_697851.1 CDS purL NC_004310.3 813719 815941 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase II complement(813719..815941) Brucella suis 1330 1166505 NP_697852.1 CDS BR0838 NC_004310.3 816128 816529 R lipoprotein complement(816128..816529) Brucella suis 1330 1166506 NP_697853.1 CDS BR0839 NC_004310.3 816589 817236 R identified by match to protein family HMM PF00043; glutathione S-transferase complement(816589..817236) Brucella suis 1330 1166507 NP_697854.1 CDS purQ NC_004310.3 817488 818159 R catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase I complement(817488..818159) Brucella suis 1330 1166508 NP_697855.1 CDS BR0841 NC_004310.3 818182 818424 R With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; phosphoribosylformylglycinamidine synthase subunit PurS complement(818182..818424) Brucella suis 1330 1166509 NP_697856.1 CDS purC NC_004310.3 818540 819304 R catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(818540..819304) Brucella suis 1330 1166510 NP_697857.1 CDS BR0843 NC_004310.3 819560 819883 D identified by similarity to OMNI:NTL02ML0054; hypothetical protein 819560..819883 Brucella suis 1330 1166511 NP_697858.1 CDS BR0844 NC_004310.3 819948 820715 D identified by similarity to EGAD:11526; match to protein family HMM PF03328; hydroxyacid aldolase 819948..820715 Brucella suis 1330 1166512 NP_697859.1 CDS BR0845 NC_004310.3 820764 821330 R identified by similarity to GP:15074696; hypothetical protein complement(820764..821330) Brucella suis 1330 1166513 NP_697860.1 CDS BR0846 NC_004310.3 821340 821441 R hypothetical protein complement(821340..821441) Brucella suis 1330 1166514 NP_697861.1 CDS BR0847 NC_004310.3 821529 821630 R hypothetical protein complement(821529..821630) Brucella suis 1330 1166515 NP_697862.1 CDS BR0848 NC_004310.3 821683 822474 D identified by match to protein family HMM PF00903; glyoxalase 821683..822474 Brucella suis 1330 1166516 NP_697863.1 CDS purB NC_004310.3 822700 824001 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(822700..824001) Brucella suis 1330 1166517 NP_697864.1 CDS rpe NC_004310.3 824028 824705 R identified by similarity to EGAD:101737; match to protein family HMM PF00834; match to protein family HMM TIGR01163; ribulose-phosphate 3-epimerase complement(824028..824705) Brucella suis 1330 1166518 NP_697865.1 CDS BR0851 NC_004310.3 824863 825789 R Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA; lipid A biosynthesis lauroyl acyltransferase complement(824863..825789) Brucella suis 1330 1166519 NP_697866.1 CDS BR0852 NC_004310.3 825803 826831 R identified by match to protein family HMM PF00107; alcohol dehydrogenase complement(825803..826831) Brucella suis 1330 1166520 NP_697867.1 CDS BR0853 NC_004310.3 826913 828190 R FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP.; 3-oxoacyl-ACP synthase complement(826913..828190) Brucella suis 1330 1166521 NP_697868.1 CDS BR0854 NC_004310.3 828192 829373 R FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(828192..829373) Brucella suis 1330 1166522 NP_697869.1 CDS BR0855 NC_004310.3 829521 829802 R Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; acyl carrier protein complement(829521..829802) Brucella suis 1330 1166523 NP_697870.1 CDS BR0856 NC_004310.3 830003 830764 R identified by similarity to OMNI:NTL02ML6731; match to protein family HMM PF05838; hypothetical protein complement(830003..830764) Brucella suis 1330 1166524 NP_697871.1 CDS galM NC_004310.3 830980 832002 D identified by similarity to EGAD:30590; match to protein family HMM PF01263; aldose 1-epimerase 830980..832002 Brucella suis 1330 1166525 NP_697872.1 CDS BR0858 NC_004310.3 831999 832916 R identified by similarity to SP:P37647; match to protein family HMM PF00294; 2-dehydro-3-deoxygluconokinase complement(831999..832916) Brucella suis 1330 1166526 NP_697873.1 CDS BR0859 NC_004310.3 833117 833848 D identified by similarity to GP:15141057; hypothetical protein 833117..833848 Brucella suis 1330 1166527 NP_697874.1 CDS phnM NC_004310.3 833852 834991 D identified by match to protein family HMM PF01979; PhnM protein 833852..834991 Brucella suis 1330 1166528 NP_697875.1 CDS BR0861 NC_004310.3 834988 835671 R identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase complement(834988..835671) Brucella suis 1330 1166529 NP_697876.1 CDS BR0863 NC_004310.3 836908 837930 D identified by similarity to OMNI:CC1306; match to protein family HMM PF01207; match to protein family HMM TIGR00742; tRNA-dihydrouridine synthase A 836908..837930 Brucella suis 1330 1166531 NP_697877.1 CDS BR0864 NC_004310.3 837927 838631 R identified by similarity to OMNI:NTL02ML0447; match to protein family HMM PF00077; hypothetical protein complement(837927..838631) Brucella suis 1330 1166532 NP_697878.1 CDS BR0865 NC_004310.3 838631 838825 R identified by similarity to OMNI:NTL02ML0446; hypothetical protein complement(838631..838825) Brucella suis 1330 1166533 NP_697879.1 CDS cobS NC_004310.3 838845 839627 R catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole; cobalamin synthase complement(838845..839627) Brucella suis 1330 1166534 NP_697880.1 CDS cobT NC_004310.3 839781 840800 D catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole; nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 839781..840800 Brucella suis 1330 1166535 NP_697881.1 CDS BR0868 NC_004310.3 840908 841387 R identified by match to protein family HMM PF01037; AsnC family transcriptional regulator complement(840908..841387) Brucella suis 1330 1166536 NP_697882.1 CDS BR0869 NC_004310.3 841516 842157 R identified by similarity to GP:15074814; hypothetical protein complement(841516..842157) Brucella suis 1330 1166537 NP_697883.1 CDS BR0870 NC_004310.3 842254 842823 R identified by match to protein family HMM PF00565; nuclease domain-containing protein complement(842254..842823) Brucella suis 1330 1166538 NP_697884.1 CDS BR0871 NC_004310.3 842794 843072 D hypothetical protein 842794..843072 Brucella suis 1330 1166539 NP_697885.1 CDS BR0872 NC_004310.3 843444 844247 D identified by similarity to EGAD:35423; exopolysacchride production negative regulator exoR 843444..844247 Brucella suis 1330 1166540 NP_697886.1 CDS xth-1 NC_004310.3 844306 845088 R identified by match to protein family HMM PF03372; match to protein family HMM TIGR00195; match to protein family HMM TIGR00633; exodeoxyribonuclease III complement(844306..845088) Brucella suis 1330 1166541 NP_697887.1 CDS BR0874 NC_004310.3 845257 845964 D identified by similarity to GP:15075908; match to protein family HMM PF04391; hypothetical protein 845257..845964 Brucella suis 1330 1166542 NP_697888.1 CDS BR0875 NC_004310.3 846045 846371 R identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein complement(846045..846371) Brucella suis 1330 1166543 NP_697889.1 CDS dgt NC_004310.3 846538 847746 D dGTPase type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate; deoxyguanosinetriphosphate triphosphohydrolase-like protein 846538..847746 Brucella suis 1330 1166544 NP_697890.1 CDS argS NC_004310.3 847968 849725 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 847968..849725 Brucella suis 1330 1166545 NP_697891.1 CDS BR0878 NC_004310.3 849937 852873 D identified by similarity to OMNI:NTL02ML0862; hypothetical protein 849937..852873 Brucella suis 1330 1166546 NP_697892.1 CDS BR0879 NC_004310.3 853074 854087 D identified by match to protein family HMM PF00933; glycosyl hydrolase 853074..854087 Brucella suis 1330 1166547 NP_697893.1 CDS scpA NC_004310.3 854274 855011 D identified by similarity to GP:14021929; match to protein family HMM PF02616; segregation and condensation protein A 854274..855011 Brucella suis 1330 1166548 NP_697894.1 CDS scpB NC_004310.3 855004 855729 D identified by similarity to OMNI:NTL02ML0859; match to protein family HMM PF04079; match to protein family HMM TIGR00281; segregation and condensation protein B 855004..855729 Brucella suis 1330 1166549 NP_697895.1 CDS tatA NC_004310.3 855851 856093 D TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes; twin-arginine translocation protein TatA 855851..856093 Brucella suis 1330 1166550 NP_697896.1 CDS BR0883 NC_004310.3 856174 856785 D mediates the export of protein precursors bearing twin-arginine signal peptides; sec-independent translocase 856174..856785 Brucella suis 1330 1166551 NP_697897.1 CDS tatC NC_004310.3 856782 857606 D identified by similarity to EGAD:10132; match to protein family HMM PF00902; match to protein family HMM TIGR00945; Sec-independent protein translocase TatC 856782..857606 Brucella suis 1330 1166552 NP_697898.1 CDS serS NC_004310.3 857683 858966 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 857683..858966 Brucella suis 1330 1166553 NP_697899.1 CDS surE NC_004310.3 859115 859882 D catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate; stationary phase survival protein SurE 859115..859882 Brucella suis 1330 1166554 NP_697900.1 CDS pcm NC_004310.3 859948 860547 D catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins; protein-L-isoaspartate O-methyltransferase 859948..860547 Brucella suis 1330 1166555 NP_697901.1 CDS BR0888 NC_004310.3 860941 862224 D identified by match to protein family HMM PF01476; match to protein family HMM PF01551; M24/M37 family peptidase 860941..862224 Brucella suis 1330 1166556 NP_697902.1 CDS BR0889 NC_004310.3 862273 863139 R identified by similarity to OMNI:NTL02ML0849; match to protein family HMM PF05673; hypothetical protein complement(862273..863139) Brucella suis 1330 1166557 NP_697903.1 CDS BR0890 NC_004310.3 863299 863640 D identified by similarity to SP:Q9ZG87; match to protein family HMM PF02699; match to protein family HMM TIGR00739; preprotein translocase subunit Yaj subunit 863299..863640 Brucella suis 1330 1166558 NP_697904.1 CDS BR0891 NC_004310.3 863729 866086 D part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 863729..866086 Brucella suis 1330 1166559 NP_697905.1 CDS BR0892 NC_004310.3 866089 866478 D identified by similarity to GP:14021915; match to protein family HMM PF04635; hypothetical protein 866089..866478 Brucella suis 1330 1166560 NP_697906.1 CDS BR0893 NC_004310.3 866484 867317 D identified by similarity to OMNI:NTL02ML0845; hypothetical protein 866484..867317 Brucella suis 1330 1166561 NP_697907.1 CDS BR0894 NC_004310.3 867369 868769 R TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid complement(867369..868769) Brucella suis 1330 1166562 NP_697908.1 CDS BR0895 NC_004310.3 869029 869175 R identified by similarity to GP:15074478; hypothetical protein complement(869029..869175) Brucella suis 1330 1166563 NP_697909.1 CDS BR0896 NC_004310.3 869449 870585 D identified by similarity to OMNI:NTL02ML0840; hypothetical protein 869449..870585 Brucella suis 1330 1166564 NP_697910.1 CDS BR0897 NC_004310.3 870582 871151 D hypothetical protein 870582..871151 Brucella suis 1330 1166565 NP_697911.1 CDS tig NC_004310.3 871531 872988 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 871531..872988 Brucella suis 1330 1166567 NP_697912.1 CDS gatB NC_004310.3 873138 874640 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 873138..874640 Brucella suis 1330 1166568 NP_697913.1 CDS BR0900 NC_004310.3 874640 875143 D identified by match to protein family HMM PF00583; acetyltransferase 874640..875143 Brucella suis 1330 1166569 NP_697914.1 CDS BR0901 NC_004310.3 875188 875331 R hypothetical protein complement(875188..875331) Brucella suis 1330 1166570 NP_697915.1 CDS BR0902 NC_004310.3 875303 875713 D Provides the input to the respiratory chain from the NAD-linked dehydrogenases of the citric acid cycle. The complex couples the oxidation of NADH and the reduction of ubiquinone, to the generation of a proton gradient which is then used for ATP synthesis; NADH dehydrogenase 875303..875713 Brucella suis 1330 1166571 NP_697916.1 CDS BR0903 NC_004310.3 875773 875898 D hypothetical protein 875773..875898 Brucella suis 1330 1166572 NP_697917.1 CDS BR0904 NC_004310.3 875907 876377 D identified by similarity to GP:15074249; hypothetical protein 875907..876377 Brucella suis 1330 1166573 NP_697918.1 CDS aat NC_004310.3 876421 876954 R leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys; leucyl/phenylalanyl-tRNA--protein transferase complement(876421..876954) Brucella suis 1330 1166574 NP_697919.1 CDS accC NC_004310.3 877042 878400 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit complement(877042..878400) Brucella suis 1330 1166575 NP_697920.1 CDS accB NC_004310.3 878450 878920 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit complement(878450..878920) Brucella suis 1330 1166576 NP_697921.1 CDS aroQ NC_004310.3 878922 879395 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(878922..879395) Brucella suis 1330 1166577 NP_697922.1 CDS BR0909 NC_004310.3 879639 880436 R identified by match to protein family HMM PF01323; hypothetical protein complement(879639..880436) Brucella suis 1330 1166578 NP_697923.1 CDS BR0910 NC_004310.3 880484 881899 R identified by similarity to GP:14021229; match to protein family HMM PF01435; hypothetical protein complement(880484..881899) Brucella suis 1330 1166579 NP_697924.1 CDS BR0911 NC_004310.3 882091 883254 D identified by match to protein family HMM PF00155; class I aminotransferase 882091..883254 Brucella suis 1330 1166580 NP_697925.1 CDS BR0912 NC_004310.3 883373 886141 R identified by match to protein family HMM TIGR00757; ribonuclease Rne/Rng domain-containing protein complement(883373..886141) Brucella suis 1330 1166581 NP_697926.1 CDS BR0913 NC_004310.3 886144 886329 D hypothetical protein 886144..886329 Brucella suis 1330 1166582 NP_697927.1 CDS BR0914 NC_004310.3 886681 886782 R hypothetical protein complement(886681..886782) Brucella suis 1330 1166583 NP_697928.1 CDS BR0915 NC_004310.3 886820 888088 D identified by similarity to OMNI:NTL02ML0166; match to protein family HMM PF01520; N-acetylmuramoyl-L-alanine amidase 886820..888088 Brucella suis 1330 1166584 NP_697929.1 CDS BR0916 NC_004310.3 888368 890827 D identified by similarity to SP:P02918; match to protein family HMM PF00905; match to protein family HMM PF00912; match to protein family HMM TIGR02074; penicillin-binding protein 1A 888368..890827 Brucella suis 1330 1166585 NP_697930.1 CDS BR0918 NC_004310.3 892155 892319 R hypothetical protein complement(892155..892319) Brucella suis 1330 1166587 NP_697931.1 CDS BR0919 NC_004310.3 892312 892623 D identified by similarity to EGAD:46813; IS711, transposase orfA 892312..892623 Brucella suis 1330 1166588 NP_697932.1 CDS BR0921 NC_004310.3 893102 893203 R hypothetical protein complement(893102..893203) Brucella suis 1330 1166590 NP_697933.1 CDS BR0922 NC_004310.3 893200 893466 R hypothetical protein complement(893200..893466) Brucella suis 1330 1166591 NP_697934.1 CDS BR0923 NC_004310.3 893733 894560 R identified by similarity to GP:15074676; match to protein family HMM PF04305; hypothetical protein complement(893733..894560) Brucella suis 1330 1166592 NP_697935.1 CDS bcp NC_004310.3 894582 895046 R identified by similarity to EGAD:18740; match to protein family HMM PF00578; bacterioferritin comigratory protein complement(894582..895046) Brucella suis 1330 1166593 NP_697936.1 CDS BR0925 NC_004310.3 895291 898731 D identified by similarity to GP:14021072; hypothetical protein 895291..898731 Brucella suis 1330 1166594 NP_697937.1 CDS tyrS NC_004310.3 898790 900043 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase complement(898790..900043) Brucella suis 1330 1166595 NP_697938.1 CDS anmK NC_004310.3 900159 901280 D catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling; anhydro-N-acetylmuramic acid kinase 900159..901280 Brucella suis 1330 1166596 NP_697939.1 CDS qacH NC_004310.3 901277 901609 R identified by similarity to GP:12024949; match to protein family HMM PF00893; quaternary ammonium compound-resistance protein complement(901277..901609) Brucella suis 1330 1166597 NP_697940.1 CDS BR0929 NC_004310.3 901721 902395 R identified by similarity to GP:15074671; hypothetical protein complement(901721..902395) Brucella suis 1330 1166598 NP_697941.1 CDS BR0930 NC_004310.3 902600 903778 D identified by similarity to EGAD:14639; match to protein family HMM PF00266; cysteine desulfurase 902600..903778 Brucella suis 1330 1166599 NP_697942.1 CDS BR0931 NC_004310.3 903959 905482 D with SufCD activates cysteine desulfurase SufS; cysteine desulfurase 903959..905482 Brucella suis 1330 1166600 NP_697943.1 CDS BR0932 NC_004310.3 905550 906305 D identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978; ABC transporter ATP-binding protein 905550..906305 Brucella suis 1330 1166601 NP_697944.1 CDS BR0933 NC_004310.3 906319 907596 D identified by similarity to OMNI:NTL02ML0017; match to protein family HMM PF01458; match to protein family HMM TIGR01981; hypothetical protein 906319..907596 Brucella suis 1330 1166602 NP_697945.1 CDS BR0934 NC_004310.3 907678 908922 D identified by match to protein family HMM PF00266; match to protein family HMM TIGR01979; class V aminotransferase 907678..908922 Brucella suis 1330 1166603 NP_697946.1 CDS BR0935 NC_004310.3 908919 909338 D identified by similarity to GP:14021086; match to protein family HMM PF01883; hypothetical protein 908919..909338 Brucella suis 1330 1166604 NP_697947.1 CDS BR0936 NC_004310.3 909372 910343 R identified by match to protein family HMM PF00535; glycosyl transferase group 2 family protein complement(909372..910343) Brucella suis 1330 1166605 NP_697948.1 CDS ppnK NC_004310.3 910746 911543 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 910746..911543 Brucella suis 1330 1166607 NP_697949.1 CDS BR0938 NC_004310.3 911871 913319 D identified by similarity to EGAD:20681; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD-box ATP dependent DNA helicase 911871..913319 Brucella suis 1330 1166608 NP_697950.1 CDS BR0939 NC_004310.3 913556 913936 R identified by match to protein family HMM PF01521; match to protein family HMM TIGR00049; HesB/YadR/YfhF family protein complement(913556..913936) Brucella suis 1330 1166609 NP_697951.1 CDS BR0940 NC_004310.3 914129 914752 D identified by similarity to OMNI:NTL02ML0072; hypothetical protein 914129..914752 Brucella suis 1330 1166610 NP_697952.1 CDS BR0941 NC_004310.3 914737 914829 D hypothetical protein 914737..914829 Brucella suis 1330 1166611 NP_697953.1 CDS BR0942 NC_004310.3 914833 915033 D identified by match to protein family HMM PF00403; heavy metal-binding domain-containing protein 914833..915033 Brucella suis 1330 1166612 NP_697954.1 CDS BR0943 NC_004310.3 915077 915322 D hypothetical protein 915077..915322 Brucella suis 1330 1166613 NP_697955.1 CDS BR0944 NC_004310.3 915360 916028 D identified by similarity to OMNI:NTL02ML0876; match to protein family HMM PF01135; protein-L-isoaspartate O-methyltransferase 915360..916028 Brucella suis 1330 1166614 NP_697956.1 CDS BR0945 NC_004310.3 916167 917537 D identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844; outer membrane efflux family protein 916167..917537 Brucella suis 1330 1166615 NP_697957.1 CDS BR0946 NC_004310.3 917787 918518 D identified by similarity to GP:14021943; hypothetical protein 917787..918518 Brucella suis 1330 1166616 NP_697958.1 CDS BR0947 NC_004310.3 918613 918816 D hypothetical protein 918613..918816 Brucella suis 1330 1166617 NP_697959.1 CDS valS NC_004310.3 918809 921541 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 918809..921541 Brucella suis 1330 1166618 NP_697960.1 CDS BR0950 NC_004310.3 923299 924174 R identified by match to protein family HMM PF03446; oxidoreductase complement(923299..924174) Brucella suis 1330 1166620 NP_697961.1 CDS BR0951 NC_004310.3 924202 924822 R identified by match to protein family HMM PF02798; glutathione S-transferase domain-containing protein complement(924202..924822) Brucella suis 1330 1166621 NP_697962.1 CDS BR0952 NC_004310.3 924995 925828 R identified by similarity to EGAD:6543; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease complement(924995..925828) Brucella suis 1330 1166622 NP_697963.1 CDS BR0953 NC_004310.3 925831 926553 R identified by similarity to EGAD:8421; match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease complement(925831..926553) Brucella suis 1330 1166623 NP_697964.1 CDS BR0954 NC_004310.3 926569 926748 R hypothetical protein complement(926569..926748) Brucella suis 1330 1166624 NP_697965.1 CDS BR0955 NC_004310.3 926796 927602 R identified by similarity to EGAD:37042; match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein complement(926796..927602) Brucella suis 1330 1166625 NP_697966.1 CDS mobB NC_004310.3 927947 928450 R identified by similarity to SP:P32125; match to protein family HMM PF03205; match to protein family HMM TIGR00176; molybdopterin-guanine dinucleotide biosynthesis protein B complement(927947..928450) Brucella suis 1330 1166626 NP_697967.1 CDS mobA NC_004310.3 928447 929112 R identified by similarity to SP:P32173; molybdopterin-guanine dinucleotide biosynthesis protein A complement(928447..929112) Brucella suis 1330 1166627 NP_697968.1 CDS moaA NC_004310.3 929288 930322 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; molybdenum cofactor biosynthesis protein A complement(929288..930322) Brucella suis 1330 1166628 NP_697969.1 CDS BR0959 NC_004310.3 930509 930868 D identified by similarity to OMNI:NTL02ML0426; hypothetical protein 930509..930868 Brucella suis 1330 1166629 NP_697970.1 CDS BR0960 NC_004310.3 930936 932042 R identified by match to protein family HMM PF01360; monooxygenase complement(930936..932042) Brucella suis 1330 1166630 NP_697971.1 CDS fumB NC_004310.3 932386 934005 R identified by similarity to SP:P00923; match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723; fumarate hydratase, class I complement(932386..934005) Brucella suis 1330 1166631 NP_697972.1 CDS BR0962 NC_004310.3 934521 936239 D identified by similarity to GP:15156702; hypothetical protein 934521..936239 Brucella suis 1330 1166632 NP_697973.1 CDS BR0963 NC_004310.3 936734 936859 R hypothetical protein complement(936734..936859) Brucella suis 1330 1166634 NP_697974.1 CDS BR0964 NC_004310.3 937040 937291 R identified by similarity to GP:15159178; match to protein family HMM PF04226; hypothetical protein complement(937040..937291) Brucella suis 1330 1166636 NP_697975.1 CDS BR0965 NC_004310.3 937446 937607 D hypothetical protein 937446..937607 Brucella suis 1330 1166637 NP_697976.1 CDS BR0966 NC_004310.3 937800 938825 R identified by match to protein family HMM PF00589; phage integrase site specific recombinase complement(937800..938825) Brucella suis 1330 1166639 NP_697977.1 CDS BR0967 NC_004310.3 939000 940202 D hypothetical protein 939000..940202 Brucella suis 1330 1166640 NP_697978.1 CDS BR0968 NC_004310.3 940199 940429 D hypothetical protein 940199..940429 Brucella suis 1330 1166641 NP_697979.1 CDS BR0969 NC_004310.3 940426 940701 D hypothetical protein 940426..940701 Brucella suis 1330 1166642 NP_697980.1 CDS BR0970 NC_004310.3 940724 941311 D hypothetical protein 940724..941311 Brucella suis 1330 1166643 NP_697981.1 CDS BR0971 NC_004310.3 941546 942256 D identified by similarity to EGAD:151783; hypothetical protein 941546..942256 Brucella suis 1330 1166644 NP_697982.1 CDS BR0972 NC_004310.3 942604 942774 R identified by similarity to EGAD:176501; hypothetical protein complement(942604..942774) Brucella suis 1330 1166645 NP_697983.1 CDS BR0973 NC_004310.3 942792 942971 D hypothetical protein 942792..942971 Brucella suis 1330 1166646 NP_697984.1 CDS BR0974 NC_004310.3 943122 943436 R identified by similarity to GP:15073548; hypothetical protein complement(943122..943436) Brucella suis 1330 1166647 NP_697985.1 CDS BR0975 NC_004310.3 943436 943756 R identified by similarity to GP:15073547; hypothetical protein complement(943436..943756) Brucella suis 1330 1166648 NP_697986.1 CDS BR0977 NC_004310.3 944544 944855 D identified by similarity to EGAD:46813; IS711, transposase orfA 944544..944855 Brucella suis 1330 1166650 NP_697987.1 CDS BR0979 NC_004310.3 945335 946054 D hypothetical protein 945335..946054 Brucella suis 1330 1166652 NP_697988.1 CDS BR0980 NC_004310.3 946189 947835 D hypothetical protein 946189..947835 Brucella suis 1330 1166653 NP_697989.1 CDS BR0981 NC_004310.3 948161 949393 D identified by similarity to GP:5616097; glycosyl transferase WboA 948161..949393 Brucella suis 1330 1166654 NP_697990.1 CDS BR0982 NC_004310.3 949390 950949 D identified by similarity to EGAD:103475; match to protein family HMM PF00534; group 1 glycosyl transferase 949390..950949 Brucella suis 1330 1166655 NP_697991.1 CDS BR0983 NC_004310.3 950930 951151 R hypothetical protein complement(950930..951151) Brucella suis 1330 1166656 NP_697992.1 CDS BR0984 NC_004310.3 951392 952054 D identified by similarity to OMNI:PG0293; match to protein family HMM PF05838; secretion activator protein 951392..952054 Brucella suis 1330 1166657 NP_697993.1 CDS BR0985 NC_004310.3 952018 952287 R hypothetical protein complement(952018..952287) Brucella suis 1330 1166658 NP_697994.1 CDS BR0986 NC_004310.3 952423 952674 D hypothetical protein 952423..952674 Brucella suis 1330 1166659 NP_697995.1 CDS BR0987 NC_004310.3 952776 952877 D hypothetical protein 952776..952877 Brucella suis 1330 1166660 NP_697996.1 CDS BR0988 NC_004310.3 952883 953023 D hypothetical protein 952883..953023 Brucella suis 1330 1166661 NP_697997.1 CDS BR0989 NC_004310.3 953014 953361 D identified by similarity to EGAD:91898; match to protein family HMM PF03960; match to protein family HMM TIGR00014; arsenate reductase 953014..953361 Brucella suis 1330 1166662 NP_697998.1 CDS BR0990 NC_004310.3 953732 954997 D identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein 953732..954997 Brucella suis 1330 1166663 NP_697999.1 CDS BR0991 NC_004310.3 955108 956298 D identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 955108..956298 Brucella suis 1330 1166664 NP_698000.1 CDS tmk NC_004310.3 956389 957024 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 956389..957024 Brucella suis 1330 1166665 NP_698001.1 CDS BR0993 NC_004310.3 957021 958103 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 957021..958103 Brucella suis 1330 1166666 NP_698002.1 CDS BR0994 NC_004310.3 958123 958272 D hypothetical protein 958123..958272 Brucella suis 1330 1166667 NP_698003.1 CDS metG NC_004310.3 958272 959819 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 958272..959819 Brucella suis 1330 1166668 NP_698004.1 CDS BR0996 NC_004310.3 959828 960619 D identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010; TatD family hydrolase 959828..960619 Brucella suis 1330 1166669 NP_698005.1 CDS BR0997 NC_004310.3 960622 961440 D identified by similarity to GP:15074532; match to protein family HMM PF00753; hypothetical protein 960622..961440 Brucella suis 1330 1166670 NP_698006.1 CDS BR0998 NC_004310.3 961490 963289 R responsible for transport of beta-1,2-glucans from the cytoplasm to periplasm; inner membrane ABC transporter permease component; Cgt; ChvA; NdvA; cyclic beta-1,2-glucan ABC transporter complement(961490..963289) Brucella suis 1330 1166671 NP_698007.1 CDS BR0999 NC_004310.3 963378 963482 D hypothetical protein 963378..963482 Brucella suis 1330 1166672 YP_089633.1 CDS rluC NC_004310.3 963602 964582 D identified by similarity to EGAD:7861; match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase C 963602..964582 Brucella suis 1330 1166673 NP_698008.1 CDS BR1001 NC_004310.3 964585 965508 D identified by match to protein family HMM PF00892; hypothetical protein 964585..965508 Brucella suis 1330 1166674 NP_698009.1 CDS BR1002 NC_004310.3 965505 966170 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549; HAD superfamily hydrolase 965505..966170 Brucella suis 1330 1166675 NP_698010.1 CDS BR1003 NC_004310.3 966212 966994 D identified by similarity to GP:15156553; hypothetical protein 966212..966994 Brucella suis 1330 1166676 NP_698011.1 CDS glnA NC_004310.3 967120 968529 R identified by match to protein family HMM PF00120; match to protein family HMM PF03951; match to protein family HMM TIGR00653; glutamine synthetase complement(967120..968529) Brucella suis 1330 1166677 NP_698012.1 CDS glnB NC_004310.3 968677 969015 R identified by similarity to EGAD:35417; match to protein family HMM PF00543; nitrogen regulatory protein P-II complement(968677..969015) Brucella suis 1330 1166678 NP_698013.1 CDS BR1006 NC_004310.3 969322 970827 D identified by similarity to OMNI:CC1965; match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197; hypothetical protein 969322..970827 Brucella suis 1330 1166679 NP_698014.1 CDS BR1007 NC_004310.3 970858 971130 R hypothetical protein complement(970858..971130) Brucella suis 1330 1166680 NP_698015.1 CDS cbbZ NC_004310.3 971127 971831 R catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate; phosphoglycolate phosphatase complement(971127..971831) Brucella suis 1330 1166681 NP_698016.1 CDS BR1009 NC_004310.3 971886 971999 D hypothetical protein 971886..971999 Brucella suis 1330 1166682 NP_698017.1 CDS rpiA NC_004310.3 972178 972876 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 972178..972876 Brucella suis 1330 1166683 NP_698018.1 CDS BR1011 NC_004310.3 972902 973438 D identified by similarity to OMNI:NTL02ML0413; hypothetical protein 972902..973438 Brucella suis 1330 1166684 NP_698019.1 CDS gor NC_004310.3 973592 974986 D catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase 973592..974986 Brucella suis 1330 1166685 NP_698020.1 CDS dhs NC_004310.3 975195 976583 D identified by match to protein family HMM PF01474; match to protein family HMM TIGR01358; phospho-2-dehydro-3-deoxyheptonate aldolase, class II 975195..976583 Brucella suis 1330 1166686 NP_698021.1 CDS dgkA NC_004310.3 976687 977037 D identified by similarity to SP:P00556; match to protein family HMM PF01219; diacylglycerol kinase 976687..977037 Brucella suis 1330 1166687 NP_698022.1 CDS nadE NC_004310.3 977129 978781 D NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 977129..978781 Brucella suis 1330 1166688 NP_698023.1 CDS gltX NC_004310.3 978793 980166 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 978793..980166 Brucella suis 1330 1166689 NP_698024.1 CDS maeB NC_004310.3 980980 983304 R NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme complement(980980..983304) Brucella suis 1330 1166690 NP_698025.1 CDS BR1018 NC_004310.3 983522 984502 R identified by match to protein family HMM PF01188; match to protein family HMM PF02746; mandelate racemase complement(983522..984502) Brucella suis 1330 1166691 NP_698026.1 CDS BR1019 NC_004310.3 984563 985738 D identified by match to protein family HMM PF01740; match to protein family HMM PF02405; toulene ABC transporter permease 984563..985738 Brucella suis 1330 1166692 NP_698027.1 CDS BR1020 NC_004310.3 985955 986812 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 985955..986812 Brucella suis 1330 1166693 NP_698028.1 CDS BR1021 NC_004310.3 986816 987811 D identified by match to protein family HMM PF02470; ABC transporter periplasmic substrate-binding protein 986816..987811 Brucella suis 1330 1166694 NP_698029.1 CDS BR1022 NC_004310.3 987835 988437 D identified by similarity to GP:15156733; match to protein family HMM PF03886; lipoprotein 987835..988437 Brucella suis 1330 1166695 NP_698030.1 CDS BR1023 NC_004310.3 988499 988606 R hypothetical protein complement(988499..988606) Brucella suis 1330 1166696 NP_698031.1 CDS BR1024 NC_004310.3 988677 993350 R identified by similarity to GP:15074750; match to protein family HMM TIGR01369; match to protein family HMM TIGR01612; hypothetical protein complement(988677..993350) Brucella suis 1330 1166697 NP_698032.1 CDS BR1025 NC_004310.3 993565 993729 D hypothetical protein 993565..993729 Brucella suis 1330 1166698 NP_698033.1 CDS BR1026 NC_004310.3 993965 994288 D identified by similarity to EGAD:5699; match to protein family HMM PF00111; (2Fe-2S) ferredoxin 993965..994288 Brucella suis 1330 1166699 NP_698034.1 CDS BR1028 NC_004310.3 994932 995552 R identified by similarity to OMNI:NTL02ML0625; hypothetical protein complement(994932..995552) Brucella suis 1330 1166701 NP_698035.1 CDS folP NC_004310.3 995710 996549 D identified by similarity to SP:P28822; match to protein family HMM PF00809; match to protein family HMM TIGR01496; dihydropteroate synthase 995710..996549 Brucella suis 1330 1166702 NP_698036.1 CDS folB NC_004310.3 996568 996927 D identified by similarity to EGAD:14090; match to protein family HMM PF02152; match to protein family HMM TIGR00525; match to protein family HMM TIGR00526; dihydroneopterin aldolase 996568..996927 Brucella suis 1330 1166703 NP_698037.1 CDS folK NC_004310.3 996924 997457 D identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 996924..997457 Brucella suis 1330 1166704 NP_698038.1 CDS BR1032 NC_004310.3 997572 998129 R identified by similarity to GP:14021684; hypothetical protein complement(997572..998129) Brucella suis 1330 1166705 NP_698039.1 CDS BR1033 NC_004310.3 998381 999454 R identified by similarity to OMNI:NTL02ML0615; match to protein family HMM PF05128; match to protein family HMM TIGR01620; hypothetical protein complement(998381..999454) Brucella suis 1330 1166706 NP_698040.1 CDS BR1034 NC_004310.3 999451 1000911 R identified by similarity to GP:14021682; match to protein family HMM PF04317; hypothetical protein complement(999451..1000911) Brucella suis 1330 1166707 NP_698041.1 CDS BR1035 NC_004310.3 1001004 1001504 R identified by similarity to GP:14021681; hypothetical protein complement(1001004..1001504) Brucella suis 1330 1166708 NP_698042.1 CDS dksA NC_004310.3 1001901 1002317 D identified by similarity to EGAD:19456; match to protein family HMM PF01258; dnaK suppressor protein 1001901..1002317 Brucella suis 1330 1166709 NP_698043.1 CDS BR1037 NC_004310.3 1002327 1002422 D hypothetical protein 1002327..1002422 Brucella suis 1330 1166710 NP_698044.1 CDS BR1038 NC_004310.3 1002486 1003718 R hypothetical protein complement(1002486..1003718) Brucella suis 1330 1166711 NP_698045.1 CDS BR1039 NC_004310.3 1003944 1006781 D identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase/response regulator 1003944..1006781 Brucella suis 1330 1166712 NP_698046.1 CDS BR1040 NC_004310.3 1006806 1008014 D identified by similarity to GP:15140178; match to protein family HMM PF03486; hypothetical protein 1006806..1008014 Brucella suis 1330 1166713 NP_698047.1 CDS BR1041 NC_004310.3 1008045 1009367 D identified by match to protein family HMM PF00144; hypothetical protein 1008045..1009367 Brucella suis 1330 1166714 NP_698048.1 CDS BR1043 NC_004310.3 1010675 1014469 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1010675..1014469) Brucella suis 1330 1166716 NP_698049.1 CDS BR1044 NC_004310.3 1014522 1014761 D hypothetical protein 1014522..1014761 Brucella suis 1330 1166717 NP_698050.1 CDS BR1045 NC_004310.3 1015171 1015659 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(1015171..1015659) Brucella suis 1330 1166718 NP_698051.1 CDS BR1046 NC_004310.3 1015900 1016397 R catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase complement(1015900..1016397) Brucella suis 1330 1166719 NP_698052.1 CDS BR1047 NC_004310.3 1016847 1017692 R identified by similarity to OMNI:NTL02ML0109; match to protein family HMM PF00582; hypothetical protein complement(1016847..1017692) Brucella suis 1330 1166720 NP_698053.1 CDS BR1048 NC_004310.3 1017770 1018528 R identified by match to protein family HMM PF00994; cinA-like protein complement(1017770..1018528) Brucella suis 1330 1166721 NP_698054.1 CDS wrbA NC_004310.3 1018689 1019288 D stationary phase that binds TrpR repressor; TrpR binding protein WrbA 1018689..1019288 Brucella suis 1330 1166722 NP_698055.1 CDS BR1050 NC_004310.3 1019266 1019415 R hypothetical protein complement(1019266..1019415) Brucella suis 1330 1166723 NP_698056.1 CDS BR1051 NC_004310.3 1019593 1020819 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 1019593..1020819 Brucella suis 1330 1166725 NP_698057.1 CDS BR1052 NC_004310.3 1020914 1022521 D identified by similarity to GP:14021336; match to protein family HMM PF00270; match to protein family HMM PF00271; DEAD-box ATP dependent DNA helicase 1020914..1022521 Brucella suis 1330 1166726 NP_698058.1 CDS BR1053 NC_004310.3 1022692 1023720 D CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis; cysteine synthase A 1022692..1023720 Brucella suis 1330 1166727 NP_698059.1 CDS BR1054 NC_004310.3 1023723 1024466 D identified by similarity to GP:15156264; hypothetical protein 1023723..1024466 Brucella suis 1330 1166728 NP_698060.1 CDS BR1055 NC_004310.3 1024493 1025347 D identified by similarity to GP:15074554; match to protein family HMM PF00581; rhodanese family protein 1024493..1025347 Brucella suis 1330 1166729 NP_698061.1 CDS BR1056 NC_004310.3 1025349 1025870 D identified by match to protein family HMM PF00583; acetyltransferase 1025349..1025870 Brucella suis 1330 1166730 NP_698062.1 CDS BR1057 NC_004310.3 1025909 1026703 R identified by similarity to OMNI:NTL02ML3729; match to protein family HMM PF00990; match to protein family HMM TIGR00254; GGDEF domain-containing protein complement(1025909..1026703) Brucella suis 1330 1166731 NP_698063.1 CDS BR1058 NC_004310.3 1027268 1028758 R identified by match to protein family HMM PF02550; acetyl-CoA hydrolase/transferase complement(1027268..1028758) Brucella suis 1330 1166732 NP_698064.1 CDS BR1059 NC_004310.3 1029023 1030564 R identified by match to protein family HMM PF00083; match to protein family HMM TIGR00711; EmrB/QacA family drug resistance transporter complement(1029023..1030564) Brucella suis 1330 1166733 NP_698065.1 CDS BR1060 NC_004310.3 1030564 1031664 R identified by match to protein family HMM PF00529; HlyD family secretion protein complement(1030564..1031664) Brucella suis 1330 1166734 NP_698066.1 CDS BR1061 NC_004310.3 1032058 1033041 D identified by similarity to SP:P42327; match to protein family HMM PF00107; alcohol dehydrogenase 1032058..1033041 Brucella suis 1330 1166735 NP_698067.1 CDS pepQ NC_004310.3 1033085 1034227 R identified by similarity to OMNI:NTL01XF00221; match to protein family HMM PF00557; proline dipeptidase complement(1033085..1034227) Brucella suis 1330 1166736 NP_698068.1 CDS BR1063 NC_004310.3 1034486 1035316 R identified by similarity to GP:15157001; match to protein family HMM PF00515; hypothetical protein complement(1034486..1035316) Brucella suis 1330 1166737 NP_698069.1 CDS BR1064 NC_004310.3 1035425 1036390 R identified by similarity to GP:2708271; match to protein family HMM PF01758; sodium/bile acid symporter family protein complement(1035425..1036390) Brucella suis 1330 1166738 NP_698070.1 CDS BR1065 NC_004310.3 1036418 1036570 R hypothetical protein complement(1036418..1036570) Brucella suis 1330 1166739 NP_698071.1 CDS galE-1 NC_004310.3 1036519 1037526 R identified by similarity to EGAD:45971; match to protein family HMM PF01370; match to protein family HMM TIGR01179; UDP-glucose 4-epimerase complement(1036519..1037526) Brucella suis 1330 1166740 NP_698072.1 CDS mazG NC_004310.3 1037671 1038495 D functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase Era; nucleoside triphosphate pyrophosphohydrolase 1037671..1038495 Brucella suis 1330 1166741 NP_698073.1 CDS BR1068 NC_004310.3 1038504 1039115 R identified by similarity to OMNI:NTL02ML0717; hypothetical protein complement(1038504..1039115) Brucella suis 1330 1166742 NP_698074.1 CDS BR1069 NC_004310.3 1039158 1039742 R identified by match to protein family HMM PF00881; nitroreductase complement(1039158..1039742) Brucella suis 1330 1166743 NP_698075.1 CDS BR1070 NC_004310.3 1039980 1040972 D identified by similarity to OMNI:NTL02ML0719; hypothetical protein 1039980..1040972 Brucella suis 1330 1166744 NP_698076.1 CDS thrS NC_004310.3 1041027 1043003 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase complement(1041027..1043003) Brucella suis 1330 1166745 NP_698077.1 CDS BR1072 NC_004310.3 1043218 1044450 R identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase complement(1043218..1044450) Brucella suis 1330 1166746 NP_698078.1 CDS BR1073 NC_004310.3 1044557 1044928 R identified by similarity to OMNI:NTL02ML0724; match to protein family HMM PF01809; match to protein family HMM TIGR00278; hypothetical protein complement(1044557..1044928) Brucella suis 1330 1166747 NP_698079.1 CDS BR1074 NC_004310.3 1044930 1045370 R identified by match to protein family HMM PF01592; NifU-like protein complement(1044930..1045370) Brucella suis 1330 1166748 NP_698080.1 CDS folE NC_004310.3 1045634 1046275 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 1045634..1046275 Brucella suis 1330 1166749 NP_698081.2 CDS hisI NC_004310.3 1046298 1046717 D PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers; phosphoribosyl-AMP cyclohydrolase 1046298..1046717 Brucella suis 1330 1166750 NP_698082.1 CDS BR1077 NC_004310.3 1046934 1047881 D identified by similarity to OMNI:NTL02ML0729; match to protein family HMM PF01734; hypothetical protein 1046934..1047881 Brucella suis 1330 1166751 NP_698083.1 CDS BR1078 NC_004310.3 1048355 1049599 D identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1048355..1049599 Brucella suis 1330 1166753 NP_698084.1 CDS BR1079 NC_004310.3 1049738 1050142 D hypothetical protein 1049738..1050142 Brucella suis 1330 1166754 NP_698085.1 CDS BR1080 NC_004310.3 1051059 1051238 R hypothetical protein complement(1051059..1051238) Brucella suis 1330 1166755 NP_698086.1 CDS BR1081 NC_004310.3 1051826 1053190 R hypothetical protein complement(1051826..1053190) Brucella suis 1330 1166756 NP_698087.1 CDS BR1082 NC_004310.3 1053748 1054365 R identified by match to protein family HMM PF00239; resolvase site-specific recombinase complement(1053748..1054365) Brucella suis 1330 1166757 NP_698088.1 CDS BR1083 NC_004310.3 1055164 1055568 R identified by match to protein family HMM PF02498; BRO family protein complement(1055164..1055568) Brucella suis 1330 1166758 NP_698089.1 CDS BR1084 NC_004310.3 1056155 1057300 R identified by match to protein family HMM PF02515; CAIB/BAIF family protein complement(1056155..1057300) Brucella suis 1330 1166760 NP_698090.1 CDS BR1085 NC_004310.3 1057379 1058563 R identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; glutaryl-CoA dehydrogenase complement(1057379..1058563) Brucella suis 1330 1166761 NP_698091.1 CDS BR1086 NC_004310.3 1058665 1059597 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1058665..1059597 Brucella suis 1330 1166762 NP_698092.1 CDS BR1087 NC_004310.3 1059567 1060550 R identified by match to protein family HMM PF00296; luciferase complement(1059567..1060550) Brucella suis 1330 1166763 NP_698093.1 CDS BR1088 NC_004310.3 1060631 1063720 R identified by match to protein family HMM PF00873; AcrB/AcrD/AcrF multidrug efflux protein complement(1060631..1063720) Brucella suis 1330 1166764 NP_698094.1 CDS BR1089 NC_004310.3 1063730 1064878 R identified by similarity to OMNI:VC0165; match to protein family HMM TIGR01730; hypothetical protein complement(1063730..1064878) Brucella suis 1330 1166765 NP_698095.1 CDS BR1090 NC_004310.3 1065019 1065585 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1065019..1065585 Brucella suis 1330 1166766 NP_698096.1 CDS tgt NC_004310.3 1065622 1066755 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(1065622..1066755) Brucella suis 1330 1166767 NP_698097.1 CDS queA NC_004310.3 1066752 1067843 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(1066752..1067843) Brucella suis 1330 1166768 NP_698098.1 CDS BR1093 NC_004310.3 1067965 1068471 R identified by similarity to OMNI:NTL02ML0580; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase complement(1067965..1068471) Brucella suis 1330 1166769 NP_698099.1 CDS BR1094 NC_004310.3 1068534 1069124 R identified by similarity to OMNI:CC1584; match to protein family HMM PF00160; cyclophilin type peptidyl-prolyl cis-trans isomerase complement(1068534..1069124) Brucella suis 1330 1166770 NP_698100.1 CDS coaD NC_004310.3 1069145 1069639 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1069145..1069639) Brucella suis 1330 1166771 NP_698101.1 CDS BR1096 NC_004310.3 1069855 1070094 R hypothetical protein complement(1069855..1070094) Brucella suis 1330 1166772 NP_698102.1 CDS gyrA NC_004310.3 1070150 1072918 R negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A complement(1070150..1072918) Brucella suis 1330 1166773 NP_698103.1 CDS BR1098 NC_004310.3 1073206 1073835 D identified by similarity to OMNI:NTL02ML0590; match to protein family HMM PF01914; match to protein family HMM TIGR00427; hypothetical protein 1073206..1073835 Brucella suis 1330 1166774 NP_698104.1 CDS BR1099 NC_004310.3 1073926 1074504 R guanylate kinase complement(1073926..1074504) Brucella suis 1330 1166775 NP_698105.1 CDS BR1100 NC_004310.3 1074691 1075452 D identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1074691..1075452 Brucella suis 1330 1166776 NP_698106.1 CDS BR1101 NC_004310.3 1075803 1075943 D hypothetical protein 1075803..1075943 Brucella suis 1330 1166777 NP_698107.1 CDS BR1102 NC_004310.3 1076137 1076643 R identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621; single-stranded DNA-binding protein family complement(1076137..1076643) Brucella suis 1330 1166778 NP_698108.1 CDS BR1103 NC_004310.3 1077211 1077411 D hypothetical protein 1077211..1077411 Brucella suis 1330 1166779 NP_698109.1 CDS uvrA NC_004310.3 1077542 1080466 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 1077542..1080466 Brucella suis 1330 1166780 NP_698110.1 CDS BR1105 NC_004310.3 1080652 1080927 R identified by similarity to EGAD:8582; match to protein family HMM PF00216; DNA-binding protein HU complement(1080652..1080927) Brucella suis 1330 1166781 NP_698111.1 CDS lon NC_004310.3 1081108 1083546 R identified by similarity to EGAD:18728; match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM TIGR00763; ATP-dependent protease La complement(1081108..1083546) Brucella suis 1330 1166782 NP_698112.1 CDS BR1107 NC_004310.3 1083867 1083986 D hypothetical protein 1083867..1083986 Brucella suis 1330 1166783 NP_698113.1 CDS clpX NC_004310.3 1083978 1085252 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1083978..1085252) Brucella suis 1330 1166784 NP_698114.1 CDS clpP NC_004310.3 1085634 1086263 R hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit complement(1085634..1086263) Brucella suis 1330 1166785 NP_698115.1 CDS BR1110 NC_004310.3 1086368 1087786 R GTP-binding protein complement(1086368..1087786) Brucella suis 1330 1166786 NP_698116.1 CDS hfq NC_004310.3 1087977 1088213 R Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq complement(1087977..1088213) Brucella suis 1330 1166787 NP_698117.1 CDS BR1112 NC_004310.3 1088219 1088458 R hypothetical protein complement(1088219..1088458) Brucella suis 1330 1166788 NP_698118.1 CDS BR1113 NC_004310.3 1088442 1089272 R hypothetical protein complement(1088442..1089272) Brucella suis 1330 1166789 NP_698119.1 CDS trkA NC_004310.3 1089321 1090697 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane component complement(1089321..1090697) Brucella suis 1330 1166790 NP_698120.1 CDS ntrX NC_004310.3 1090722 1092083 R identified by similarity to EGAD:5624; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; nitrogen regulation protein NtrX complement(1090722..1092083) Brucella suis 1330 1166791 NP_698121.1 CDS ntrY NC_004310.3 1092085 1094409 R identified by similarity to EGAD:10502; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR00229; nitrogen regulation protein NtrY complement(1092085..1094409) Brucella suis 1330 1166792 NP_698122.1 CDS ntrC NC_004310.3 1094500 1095975 R identified by similarity to EGAD:19665; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199; match to protein family HMM TIGR01818; nitrogen regulation protein NtrC complement(1094500..1095975) Brucella suis 1330 1166793 NP_698123.1 CDS ntrB NC_004310.3 1095972 1097075 R identified by similarity to EGAD:22187; match to protein family HMM PF00512; match to protein family HMM PF02518; nitrogen regulation protein NtrB complement(1095972..1097075) Brucella suis 1330 1166794 NP_698124.1 CDS nifR3 NC_004310.3 1097114 1098115 R identified by similarity to EGAD:30550; match to protein family HMM PF01207; match to protein family HMM TIGR00737; nitrogen regulation protein Nifr3 complement(1097114..1098115) Brucella suis 1330 1166795 NP_698125.2 CDS ispDF NC_004310.3 1098253 1099482 D bifunctional enzyme involved in formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate and 2-C-methyl-D-erythritol 2,4-cyclodiphosphate and CMP from 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; binds divalent cations; bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1098253..1099482 Brucella suis 1330 1166796 NP_698126.1 CDS cinA NC_004310.3 1099479 1099976 D identified by similarity to GP:15074388; match to protein family HMM PF02464; match to protein family HMM TIGR00199; competence/damage-inducible protein CinA 1099479..1099976 Brucella suis 1330 1166797 NP_698127.1 CDS BR1122 NC_004310.3 1100053 1100793 D identified by match to protein family HMM PF00106; short chain dehydrogenase/reductase oxidoreductase 1100053..1100793 Brucella suis 1330 1166798 NP_698128.1 CDS BR1123 NC_004310.3 1100851 1101261 R identified by similarity to OMNI:NTL02ML0302; match to protein family HMM PF03654; hypothetical protein complement(1100851..1101261) Brucella suis 1330 1166799 NP_698129.1 CDS lipA NC_004310.3 1101315 1102283 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(1101315..1102283) Brucella suis 1330 1166800 NP_698130.1 CDS BR1125 NC_004310.3 1102393 1102554 R hypothetical protein complement(1102393..1102554) Brucella suis 1330 1166801 NP_698131.1 CDS lpdA-1 NC_004310.3 1102673 1104136 R E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1102673..1104136) Brucella suis 1330 1166802 NP_698132.1 CDS aceF NC_004310.3 1104219 1105562 R identified by similarity to SP:Q9R9N3; match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR01349; branched-chain alpha-keto acid dehydrogenase subunit E2 complement(1104219..1105562) Brucella suis 1330 1166803 NP_698133.1 CDS pdhB NC_004310.3 1105580 1106965 R catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acetyltransferase within the complex. The E1 component of the pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase(E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta complement(1105580..1106965) Brucella suis 1330 1166804 NP_698134.1 CDS pdhA NC_004310.3 1106984 1108024 R identified by similarity to SP:Q9R9N5; match to protein family HMM PF00676; pyruvate dehydrogenase complex, E1 component subunit alpha complement(1106984..1108024) Brucella suis 1330 1166805 NP_698135.1 CDS BR1130 NC_004310.3 1108163 1108492 R identified by similarity to OMNI:NTL02ML0293; match to protein family HMM PF04977; hypothetical protein complement(1108163..1108492) Brucella suis 1330 1166806 NP_698136.1 CDS BR1131 NC_004310.3 1108764 1109345 R identified by similarity to OMNI:CC1925; hypothetical protein complement(1108764..1109345) Brucella suis 1330 1166807 NP_698137.1 CDS eno NC_004310.3 1109682 1110959 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1109682..1110959) Brucella suis 1330 1166808 NP_698138.1 CDS kdsA NC_004310.3 1111146 1111979 R catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis; 2-dehydro-3-deoxyphosphooctonate aldolase complement(1111146..1111979) Brucella suis 1330 1166809 NP_698139.1 CDS pyrG NC_004310.3 1112085 1113713 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(1112085..1113713) Brucella suis 1330 1166810 NP_698140.1 CDS BR1135 NC_004310.3 1113726 1113848 R hypothetical protein complement(1113726..1113848) Brucella suis 1330 1166811 NP_698141.1 CDS BR1136 NC_004310.3 1113983 1114696 R identified by similarity to GP:15157507; match to protein family HMM PF03734; hypothetical protein complement(1113983..1114696) Brucella suis 1330 1166812 NP_698142.1 CDS secG NC_004310.3 1114929 1115375 R identified by match to protein family HMM PF03840; preprotein translocase subunit SecG complement(1114929..1115375) Brucella suis 1330 1166813 NP_698143.1 CDS tpiA NC_004310.3 1115475 1116239 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1115475..1116239) Brucella suis 1330 1166814 NP_698144.1 CDS BR1139 NC_004310.3 1116458 1118344 D rotamase 1116458..1118344 Brucella suis 1330 1166815 NP_698145.1 CDS trpD NC_004310.3 1118359 1119378 D Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 1118359..1119378 Brucella suis 1330 1166816 NP_698146.1 CDS trpC NC_004310.3 1119395 1120201 D involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 1119395..1120201 Brucella suis 1330 1166817 NP_698147.1 CDS moaC NC_004310.3 1120198 1120695 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MoaC 1120198..1120695 Brucella suis 1330 1166818 NP_698148.1 CDS moeA NC_004310.3 1120791 1122005 D identified by match to protein family HMM PF00994; match to protein family HMM PF03453; match to protein family HMM PF03454; match to protein family HMM TIGR00177; molybdopterin biosynthesis protein MoeA 1120791..1122005 Brucella suis 1330 1166819 NP_698149.1 CDS lexA NC_004310.3 1122253 1122975 D Represses a number of genes involved in the response to DNA damage; LexA repressor 1122253..1122975 Brucella suis 1330 1166820 NP_698150.1 CDS BR1145 NC_004310.3 1122969 1125500 R identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360; ComEC/Rec2 family protein complement(1122969..1125500) Brucella suis 1330 1166821 NP_698151.1 CDS BR1146 NC_004310.3 1125532 1125708 R hypothetical protein complement(1125532..1125708) Brucella suis 1330 1166822 NP_698152.1 CDS gltX NC_004310.3 1125721 1127142 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 1125721..1127142 Brucella suis 1330 1166823 NP_698153.1 CDS gltA NC_004310.3 1127371 1128663 D type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; type II citrate synthase 1127371..1128663 Brucella suis 1330 1166824 NP_698154.1 CDS lpxB NC_004310.3 1128836 1130023 R catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM; lipid-A-disaccharide synthase complement(1128836..1130023) Brucella suis 1330 1166825 NP_698155.1 CDS BR1150 NC_004310.3 1130020 1130922 R identified by similarity to GP:15074439; hypothetical protein complement(1130020..1130922) Brucella suis 1330 1166826 NP_698156.1 CDS lpxA NC_004310.3 1130903 1131739 R catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis; UDP-N-acetylglucosamine acyltransferase complement(1130903..1131739) Brucella suis 1330 1166827 NP_698157.1 CDS fabZ NC_004310.3 1131748 1132221 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase complement(1131748..1132221) Brucella suis 1330 1166828 NP_698158.1 CDS lpxD NC_004310.3 1132214 1133269 R adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase complement(1132214..1133269) Brucella suis 1330 1166829 NP_698159.1 CDS BR1154 NC_004310.3 1133323 1135668 R identified by match to protein family HMM PF01103; surface antigen complement(1133323..1135668) Brucella suis 1330 1166830 NP_698160.1 CDS BR1155 NC_004310.3 1135652 1135771 R hypothetical protein complement(1135652..1135771) Brucella suis 1330 1166831 NP_698161.1 CDS BR1156 NC_004310.3 1136004 1137143 R identified by match to protein family HMM PF00595; match to protein family HMM PF02163; match to protein family HMM TIGR00054; zinc metalloprotease complement(1136004..1137143) Brucella suis 1330 1166832 NP_698162.1 CDS cdsA NC_004310.3 1137210 1138022 R identified by similarity to EGAD:108469; match to protein family HMM PF01148; phosphatidate cytidylyltransferase complement(1137210..1138022) Brucella suis 1330 1166833 NP_698163.1 CDS uppS NC_004310.3 1138127 1138891 R catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase complement(1138127..1138891) Brucella suis 1330 1166834 NP_698164.1 CDS frr NC_004310.3 1138936 1139496 R Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor complement(1138936..1139496) Brucella suis 1330 1166835 NP_698165.2 CDS pyrH NC_004310.3 1139532 1140254 R Catalyzes the phosphorylation of UMP to UDP; uridylate kinase complement(1139532..1140254) Brucella suis 1330 1166836 NP_698166.1 CDS tsf NC_004310.3 1140421 1141338 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(1140421..1141338) Brucella suis 1330 1166837 NP_698167.1 CDS rpsB NC_004310.3 1141528 1142298 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(1141528..1142298) Brucella suis 1330 1166838 NP_698168.1 CDS BR1163 NC_004310.3 1142521 1143015 R identified by similarity to GP:9107039; hypothetical protein complement(1142521..1143015) Brucella suis 1330 1166839 NP_698169.1 CDS BR1164 NC_004310.3 1143128 1143970 R identified by similarity to OMNI:NTL02ML0524; hypothetical protein complement(1143128..1143970) Brucella suis 1330 1166840 NP_698170.1 CDS BR1165 NC_004310.3 1144114 1144578 D identified by similarity to OMNI:NTL02ML0525; match to protein family HMM PF01042; hypothetical protein 1144114..1144578 Brucella suis 1330 1166841 NP_698171.1 CDS BR1166 NC_004310.3 1144580 1145320 D identified by similarity to EGAD:9938; match to protein family HMM PF03009; glycerophosphoryl diester phosphodiesterase 1144580..1145320 Brucella suis 1330 1166842 NP_698172.1 CDS BR1167 NC_004310.3 1145375 1146562 D identified by similarity to OMNI:NTL02ML0527; match to protein family HMM PF04339; hypothetical protein 1145375..1146562 Brucella suis 1330 1166843 NP_698173.1 CDS BR1168 NC_004310.3 1146634 1147056 D identified by match to protein family HMM PF01230; HIT family protein 1146634..1147056 Brucella suis 1330 1166844 NP_698174.1 CDS clpA NC_004310.3 1147163 1149637 R identified by similarity to EGAD:17776; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01967; ATP-dependent Clp protease ATP-binding subunit ClpA complement(1147163..1149637) Brucella suis 1330 1166845 NP_698175.1 CDS clpS NC_004310.3 1149644 1150054 R involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA; ATP-dependent Clp protease adaptor protein ClpS complement(1149644..1150054) Brucella suis 1330 1166846 NP_698176.1 CDS BR1171 NC_004310.3 1150055 1150246 D hypothetical protein 1150055..1150246 Brucella suis 1330 1166847 NP_698177.1 CDS BR1172 NC_004310.3 1150480 1151898 D identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase 1150480..1151898 Brucella suis 1330 1166848 NP_698178.1 CDS BR1173 NC_004310.3 1151930 1152271 D identified by similarity to GP:15074343; hypothetical protein 1151930..1152271 Brucella suis 1330 1166849 NP_698179.1 CDS BR1174 NC_004310.3 1152385 1152822 R identified by similarity to OMNI:NTL02ML0534; hypothetical protein complement(1152385..1152822) Brucella suis 1330 1166850 NP_698180.1 CDS sda NC_004310.3 1152911 1154314 R identified by similarity to SP:P42630; match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720; L-serine dehydratase complement(1152911..1154314) Brucella suis 1330 1166851 NP_698181.1 CDS BR1176 NC_004310.3 1154512 1154637 R hypothetical protein complement(1154512..1154637) Brucella suis 1330 1166852 NP_698182.1 CDS BR1177 NC_004310.3 1154836 1155642 R identified by similarity to OMNI:NTL02ML0537; match to protein family HMM PF02698; hypothetical protein complement(1154836..1155642) Brucella suis 1330 1166853 NP_698183.1 CDS BR1178 NC_004310.3 1155805 1156791 D identified by similarity to OMNI:NTL02ML1038; hypothetical protein 1155805..1156791 Brucella suis 1330 1166854 NP_698184.1 CDS BR1179 NC_004310.3 1156802 1157188 R identified by match to protein family HMM PF00376; transcriptional regulator complement(1156802..1157188) Brucella suis 1330 1166855 NP_698185.1 CDS BR1180 NC_004310.3 1157426 1157686 D hypothetical protein 1157426..1157686 Brucella suis 1330 1166856 NP_698186.1 CDS BR1181 NC_004310.3 1157807 1158154 D identified by similarity to GP:15141218; hypothetical protein 1157807..1158154 Brucella suis 1330 1166857 NP_698187.1 CDS BR1182 NC_004310.3 1158225 1158539 D identified by similarity to GP:15156035; hypothetical protein 1158225..1158539 Brucella suis 1330 1166858 NP_698188.1 CDS BR1183 NC_004310.3 1158984 1159451 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1158984..1159451 Brucella suis 1330 1166859 NP_698189.1 CDS BR1184 NC_004310.3 1159455 1159604 R hypothetical protein complement(1159455..1159604) Brucella suis 1330 1166860 NP_698190.1 CDS BR1185 NC_004310.3 1159582 1159758 D hypothetical protein 1159582..1159758 Brucella suis 1330 1166861 NP_698191.1 CDS BR1186 NC_004310.3 1159790 1160332 D identified by similarity to OMNI:CC2122; hypothetical protein 1159790..1160332 Brucella suis 1330 1166862 NP_698192.1 CDS BR1187 NC_004310.3 1160335 1161747 R identified by similarity to GP:15159740; match to protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1160335..1161747) Brucella suis 1330 1166863 NP_698193.1 CDS pccA NC_004310.3 1162752 1164755 D identified by similarity to EGAD:2033; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786; propionyl-CoA carboxylase subunit alpha 1162752..1164755 Brucella suis 1330 1166865 NP_698194.1 CDS bhbA NC_004310.3 1164816 1166954 D MDM; functions in conversion of succinate to propionate; methylmalonyl-CoA mutase 1164816..1166954 Brucella suis 1330 1166866 NP_698195.1 CDS BR1191 NC_004310.3 1167061 1167492 R identified by similarity to GP:15140764; hypothetical protein complement(1167061..1167492) Brucella suis 1330 1166867 NP_698196.1 CDS BR1192 NC_004310.3 1167610 1169658 R identified by similarity to OMNI:NTL01BH2941; match to protein family HMM TIGR02123; hypothetical protein complement(1167610..1169658) Brucella suis 1330 1166868 NP_698197.1 CDS BR1193 NC_004310.3 1169699 1169851 R hypothetical protein complement(1169699..1169851) Brucella suis 1330 1166869 NP_698198.1 CDS BR1194 NC_004310.3 1169895 1170884 R identified by similarity to EGAD:7185; match to protein family HMM TIGR02122; TRAP transporter solute receptor TAXI family protein complement(1169895..1170884) Brucella suis 1330 1166870 NP_698199.1 CDS murI NC_004310.3 1171030 1171863 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1171030..1171863) Brucella suis 1330 1166871 NP_698200.1 CDS BR1196 NC_004310.3 1171860 1172690 R identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050; RNA methyltransferase complement(1171860..1172690) Brucella suis 1330 1166872 NP_698201.1 CDS BR1197 NC_004310.3 1172870 1173454 D identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382; ThiJ/PfpI family protein 1172870..1173454 Brucella suis 1330 1166873 NP_698202.1 CDS BR1198 NC_004310.3 1173543 1173953 D identified by similarity to OMNI:NTL03PA04336; hypothetical protein 1173543..1173953 Brucella suis 1330 1166874 NP_698203.1 CDS BR1199 NC_004310.3 1174081 1175295 D Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 1174081..1175295 Brucella suis 1330 1166875 NP_698204.1 CDS phoA NC_004310.3 1175517 1176962 D identified by similarity to SP:P00634; match to protein family HMM PF00245; alkaline phosphatase 1175517..1176962 Brucella suis 1330 1166876 NP_698205.1 CDS alaS NC_004310.3 1177114 1179771 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1177114..1179771) Brucella suis 1330 1166877 NP_698206.1 CDS recA NC_004310.3 1180164 1181249 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1180164..1181249) Brucella suis 1330 1166878 NP_698207.1 CDS BR1203 NC_004310.3 1181419 1181544 R hypothetical protein complement(1181419..1181544) Brucella suis 1330 1166879 NP_698208.1 CDS BR1204 NC_004310.3 1181580 1182242 R identified by match to protein family HMM PF00691; OmpA family protein complement(1181580..1182242) Brucella suis 1330 1166880 NP_698209.1 CDS BR1205 NC_004310.3 1182329 1182913 R identified by similarity to GP:15075335; lipoprotein complement(1182329..1182913) Brucella suis 1330 1166881 NP_698210.1 CDS BR1206 NC_004310.3 1183037 1184350 R identified by match to protein family HMM PF00004; recombination factor protein RarA complement(1183037..1184350) Brucella suis 1330 1166882 NP_698211.1 CDS BR1207 NC_004310.3 1184497 1185921 R identified by similarity to EGAD:18959; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease complement(1184497..1185921) Brucella suis 1330 1166883 NP_698212.1 CDS rplQ NC_004310.3 1186201 1186629 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(1186201..1186629) Brucella suis 1330 1166884 NP_698213.1 CDS rpoA NC_004310.3 1186791 1187804 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(1186791..1187804) Brucella suis 1330 1166885 NP_698214.1 CDS rpsK NC_004310.3 1187920 1188309 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(1187920..1188309) Brucella suis 1330 1166886 NP_698215.1 CDS rpsM NC_004310.3 1188437 1188805 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(1188437..1188805) Brucella suis 1330 1166887 NP_698216.1 CDS adk NC_004310.3 1189115 1189699 R essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase complement(1189115..1189699) Brucella suis 1330 1166888 NP_698217.1 CDS secY NC_004310.3 1189696 1191036 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1189696..1191036) Brucella suis 1330 1166889 NP_698218.1 CDS rplO NC_004310.3 1191197 1191667 R late assembly protein; 50S ribosomal protein L15 complement(1191197..1191667) Brucella suis 1330 1166890 NP_698219.1 CDS rpmD NC_004310.3 1191688 1191885 R L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 complement(1191688..1191885) Brucella suis 1330 1166891 NP_698220.1 CDS rpsE NC_004310.3 1192003 1192563 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(1192003..1192563) Brucella suis 1330 1166892 NP_698221.1 CDS rplR NC_004310.3 1192605 1192967 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(1192605..1192967) Brucella suis 1330 1166893 NP_698222.1 CDS rplF NC_004310.3 1192980 1193513 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(1192980..1193513) Brucella suis 1330 1166894 NP_698223.1 CDS rpsH NC_004310.3 1193552 1193950 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(1193552..1193950) Brucella suis 1330 1166895 NP_698224.1 CDS rpsN NC_004310.3 1193961 1194266 R located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 complement(1193961..1194266) Brucella suis 1330 1166896 NP_698225.1 CDS rplE NC_004310.3 1194294 1194851 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(1194294..1194851) Brucella suis 1330 1166897 NP_698226.1 CDS rplX NC_004310.3 1194844 1195155 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(1194844..1195155) Brucella suis 1330 1166898 NP_698227.1 CDS rplN NC_004310.3 1195168 1195536 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(1195168..1195536) Brucella suis 1330 1166899 NP_698228.1 CDS rpsQ NC_004310.3 1195605 1195847 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(1195605..1195847) Brucella suis 1330 1166900 NP_698229.1 CDS rpmC NC_004310.3 1195860 1196060 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(1195860..1196060) Brucella suis 1330 1166901 NP_698230.1 CDS rplP NC_004310.3 1196073 1196486 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(1196073..1196486) Brucella suis 1330 1166902 NP_698231.1 CDS rpsC NC_004310.3 1196525 1197235 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(1196525..1197235) Brucella suis 1330 1166903 NP_698232.1 CDS rplV NC_004310.3 1197235 1197624 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(1197235..1197624) Brucella suis 1330 1166904 NP_698233.1 CDS rpsS NC_004310.3 1197627 1197905 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(1197627..1197905) Brucella suis 1330 1166905 NP_698234.1 CDS rplB NC_004310.3 1197921 1198754 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(1197921..1198754) Brucella suis 1330 1166906 NP_698235.1 CDS rplW NC_004310.3 1198776 1199069 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(1198776..1199069) Brucella suis 1330 1166907 NP_698236.1 CDS rplD NC_004310.3 1199066 1199686 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(1199066..1199686) Brucella suis 1330 1166908 NP_698237.1 CDS rplC NC_004310.3 1199686 1200399 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(1199686..1200399) Brucella suis 1330 1166909 NP_698238.1 CDS rpsJ NC_004310.3 1200429 1200737 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(1200429..1200737) Brucella suis 1330 1166910 NP_698239.1 CDS tuf NC_004310.3 1200798 1201973 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1200798..1201973) Brucella suis 1330 1166911 NP_698240.1 CDS fusA NC_004310.3 1202037 1204121 R EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G complement(1202037..1204121) Brucella suis 1330 1166912 NP_698241.1 CDS rpsG NC_004310.3 1204152 1204622 R binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 complement(1204152..1204622) Brucella suis 1330 1166913 NP_698242.1 CDS rpsL NC_004310.3 1204689 1205060 R interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 complement(1204689..1205060) Brucella suis 1330 1166914 NP_698243.1 CDS BR1239 NC_004310.3 1205150 1205284 R hypothetical protein complement(1205150..1205284) Brucella suis 1330 1166915 NP_698244.1 CDS BR1240 NC_004310.3 1205291 1205395 R hypothetical protein complement(1205291..1205395) Brucella suis 1330 1166916 NP_698245.1 CDS BR1241 NC_004310.3 1205492 1205863 D identified by similarity to GP:15074283; hypothetical protein 1205492..1205863 Brucella suis 1330 1166917 NP_698246.1 CDS rpoC NC_004310.3 1205970 1210172 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1205970..1210172) Brucella suis 1330 1166918 NP_698247.1 CDS rpoB NC_004310.3 1210321 1214454 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta complement(1210321..1214454) Brucella suis 1330 1166919 NP_698248.1 CDS BR1244 NC_004310.3 1214440 1214544 D hypothetical protein 1214440..1214544 Brucella suis 1330 1166920 NP_698249.1 CDS rplL NC_004310.3 1214662 1215036 R present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 complement(1214662..1215036) Brucella suis 1330 1166921 NP_698250.1 CDS rplJ NC_004310.3 1215088 1215606 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1215088..1215606) Brucella suis 1330 1166922 NP_698251.1 CDS rplA NC_004310.3 1215997 1216698 R in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 complement(1215997..1216698) Brucella suis 1330 1166923 NP_698252.1 CDS rplK NC_004310.3 1216703 1217131 R binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 complement(1216703..1217131) Brucella suis 1330 1166924 NP_698253.1 CDS nusG NC_004310.3 1217334 1217861 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1217334..1217861) Brucella suis 1330 1166925 NP_698254.1 CDS secE NC_004310.3 1217885 1218124 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1217885..1218124) Brucella suis 1330 1166926 NP_698255.1 CDS tuf NC_004310.3 1218758 1219933 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1218758..1219933) Brucella suis 1330 1166928 NP_698256.1 CDS BR1252 NC_004310.3 1219884 1220084 D hypothetical protein 1219884..1220084 Brucella suis 1330 1166929 NP_698257.1 CDS BR1253 NC_004310.3 1220316 1220432 R hypothetical protein complement(1220316..1220432) Brucella suis 1330 1166932 NP_698258.1 CDS BR1254 NC_004310.3 1220564 1221424 D identified by match to protein family HMM PF00588; match to protein family HMM TIGR00186; RNA methyltransferase 1220564..1221424 Brucella suis 1330 1166933 NP_698259.1 CDS BR1256 NC_004310.3 1222086 1222847 R identified by match to protein family HMM PF01694; rhomboid family protein complement(1222086..1222847) Brucella suis 1330 1166935 NP_698260.1 CDS BR1257 NC_004310.3 1222908 1223003 D hypothetical protein 1222908..1223003 Brucella suis 1330 1166936 NP_698261.1 CDS BR1258 NC_004310.3 1223185 1223847 D identified by similarity to OMNI:NTL02ML0144; hypothetical protein 1223185..1223847 Brucella suis 1330 1166937 NP_698262.1 CDS BR1259 NC_004310.3 1224091 1224696 D identified by similarity to OMNI:NTL02ML0142; hypothetical protein 1224091..1224696 Brucella suis 1330 1166938 NP_698263.1 CDS BR1260 NC_004310.3 1224775 1225302 R identified by similarity to OMNI:NTL02ML0140; match to protein family HMM PF00132; ferripyochelin-binding protein complement(1224775..1225302) Brucella suis 1330 1166939 NP_698264.1 CDS BR1261 NC_004310.3 1225573 1225827 R identified by similarity to GP:15074417; hypothetical protein complement(1225573..1225827) Brucella suis 1330 1166940 NP_698265.1 CDS cysE NC_004310.3 1226075 1226875 R identified by match to protein family HMM PF00132; match to protein family HMM TIGR01172; serine acetyltransferase complement(1226075..1226875) Brucella suis 1330 1166941 NP_698266.1 CDS BR1263 NC_004310.3 1226915 1227037 D hypothetical protein 1226915..1227037 Brucella suis 1330 1166942 NP_698267.1 CDS BR1264 NC_004310.3 1227074 1227844 R identified by match to protein family HMM PF00561; alpha/beta hydrolase complement(1227074..1227844) Brucella suis 1330 1166943 NP_698268.1 CDS BR1265 NC_004310.3 1227878 1228357 R identified by similarity to GP:14021198; match to protein family HMM PF02643; hypothetical protein complement(1227878..1228357) Brucella suis 1330 1166944 NP_698269.1 CDS BR1266 NC_004310.3 1228731 1229312 R identified by match to protein family HMM PF00313; cold-shock family protein complement(1228731..1229312) Brucella suis 1330 1166945 NP_698270.1 CDS BR1267 NC_004310.3 1229436 1229606 R hypothetical protein complement(1229436..1229606) Brucella suis 1330 1166946 NP_698271.1 CDS gloA NC_004310.3 1229675 1230115 D identified by match to protein family HMM PF00903; lactoylglutathione lyase 1229675..1230115 Brucella suis 1330 1166947 NP_698272.1 CDS BR1269 NC_004310.3 1230167 1231195 R identified by similarity to OMNI:NT01MC4682; hypothetical protein complement(1230167..1231195) Brucella suis 1330 1166948 NP_698273.1 CDS recJ NC_004310.3 1231357 1233141 R identified by match to protein family HMM PF01368; match to protein family HMM PF02272; match to protein family HMM TIGR00644; single-stranded-DNA-specific exonuclease RecJ complement(1231357..1233141) Brucella suis 1330 1166949 NP_698274.1 CDS ddl NC_004310.3 1233191 1234252 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1233191..1234252) Brucella suis 1330 1166950 NP_698275.1 CDS BR1272 NC_004310.3 1234281 1234421 D hypothetical protein 1234281..1234421 Brucella suis 1330 1166951 NP_698276.1 CDS glpX NC_004310.3 1234600 1235586 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(1234600..1235586) Brucella suis 1330 1166952 NP_698277.1 CDS hom NC_004310.3 1235979 1237298 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1235979..1237298) Brucella suis 1330 1166953 NP_698278.1 CDS BR1275 NC_004310.3 1237434 1238654 R identified by match to protein family HMM PF00155; aminotransferase complement(1237434..1238654) Brucella suis 1330 1166954 NP_698279.1 CDS BR1276 NC_004310.3 1238785 1239216 R hypothetical protein complement(1238785..1239216) Brucella suis 1330 1166955 NP_698280.1 CDS BR1277 NC_004310.3 1239621 1240901 D identified by similarity to GP:14021808; hypothetical protein 1239621..1240901 Brucella suis 1330 1166956 NP_698281.1 CDS BR1278 NC_004310.3 1241512 1241796 D identified by similarity to OMNI:NTL02ML0128; hypothetical protein 1241512..1241796 Brucella suis 1330 1166959 NP_698282.1 CDS BR1279 NC_004310.3 1241930 1242022 D hypothetical protein 1241930..1242022 Brucella suis 1330 1166960 NP_698283.1 CDS BR1280 NC_004310.3 1242019 1242111 D hypothetical protein 1242019..1242111 Brucella suis 1330 1166961 NP_698284.1 CDS sfsA NC_004310.3 1242120 1242836 D Regulatory factor involved in maltose metabolism; sugar fermentation stimulation protein A 1242120..1242836 Brucella suis 1330 1166962 NP_698285.1 CDS map NC_004310.3 1242836 1243663 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1242836..1243663 Brucella suis 1330 1166963 NP_698286.1 CDS radC NC_004310.3 1243719 1244468 D Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC 1243719..1244468 Brucella suis 1330 1166964 NP_698287.1 CDS BR1284 NC_004310.3 1244670 1245308 D identified by similarity to GP:14018349; hypothetical protein 1244670..1245308 Brucella suis 1330 1166965 NP_698288.1 CDS cobL NC_004310.3 1245597 1246802 R identified by match to protein family HMM PF00590; match to protein family HMM TIGR01468; precorrin-6Y C5,15-methyltransferase complement(1245597..1246802) Brucella suis 1330 1166966 NP_698289.1 CDS BR1286 NC_004310.3 1246876 1248171 D identified by match to protein family HMM PF01077; match to protein family HMM PF03460; nitrite reductase 1246876..1248171 Brucella suis 1330 1166967 NP_698290.1 CDS cobH NC_004310.3 1248181 1248807 D catalyzes the interconversion of precorrin-8X and hydrogenobyrinate; precorrin-8X methylmutase 1248181..1248807 Brucella suis 1330 1166968 NP_698291.1 CDS cobI NC_004310.3 1248807 1249541 D catalyzes the formation of precorrin-3 from precorrin-2; precorrin-2 C20-methyltransferase 1248807..1249541 Brucella suis 1330 1166969 NP_698292.1 CDS BR1289 NC_004310.3 1249487 1251232 D identified by match to protein family HMM PF00590; match to protein family HMM PF01890; match to protein family HMM TIGR01466; cbiG protein/precorrin-3B C17-methyltransferase 1249487..1251232 Brucella suis 1330 1166970 NP_698293.1 CDS BR1290 NC_004310.3 1251288 1251755 R hypothetical protein complement(1251288..1251755) Brucella suis 1330 1166971 NP_698294.1 CDS BR1291 NC_004310.3 1251880 1252776 R phospholipase/carboxylesterase complement(1251880..1252776) Brucella suis 1330 1166972 NP_698295.1 CDS BR1292 NC_004310.3 1252780 1253301 R identified by match to protein family HMM PF01613; monooxygenase complement(1252780..1253301) Brucella suis 1330 1166973 NP_698296.1 CDS BR1293 NC_004310.3 1253446 1254537 D identified by similarity to SP:P02917; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1253446..1254537 Brucella suis 1330 1166974 NP_698297.1 CDS cobD NC_004310.3 1254523 1255518 R CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; cobalamin biosynthesis protein complement(1254523..1255518) Brucella suis 1330 1166975 NP_698298.1 CDS cobC NC_004310.3 1255543 1256541 R identified by similarity to SP:P21633; match to protein family HMM PF00155; cobC protein complement(1255543..1256541) Brucella suis 1330 1166976 NP_698299.1 CDS cobB NC_004310.3 1256538 1257848 R responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid; cobyrinic acid a,c-diamide synthase complement(1256538..1257848) Brucella suis 1330 1166977 NP_698300.1 CDS cobA NC_004310.3 1257845 1258693 R identified by similarity to SP:P21631; match to protein family HMM PF00590; match to protein family HMM TIGR01469; uroporphyrin-III C-methyltransferase complement(1257845..1258693) Brucella suis 1330 1166978 NP_698301.1 CDS cbiD NC_004310.3 1258784 1259890 D Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A; cobalt-precorrin-6A synthase 1258784..1259890 Brucella suis 1330 1166979 NP_698302.1 CDS cobK NC_004310.3 1259877 1260623 D CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6; cobalt-precorrin-6x reductase 1259877..1260623 Brucella suis 1330 1166980 NP_698303.1 CDS cobM NC_004310.3 1260612 1261370 R identified by similarity to SP:P21922; match to protein family HMM PF00590; match to protein family HMM TIGR01465; precorrin-4 C11-methyltransferase complement(1260612..1261370) Brucella suis 1330 1166981 NP_698304.1 CDS BR1301 NC_004310.3 1261430 1261825 R precorrin-3B C17-methyltransferase complement(1261430..1261825) Brucella suis 1330 1166982 NP_698305.1 CDS BR1302 NC_004310.3 1261818 1262264 R identified by similarity to OMNI:NTL02ML0945; hypothetical protein complement(1261818..1262264) Brucella suis 1330 1166983 NP_698306.1 CDS BR1303 NC_004310.3 1262424 1263209 D identified by similarity to OMNI:NTL02ML0946; match to protein family HMM PF01925; hypothetical protein 1262424..1263209 Brucella suis 1330 1166984 NP_698307.1 CDS BR1304 NC_004310.3 1263206 1263634 R identified by match to protein family HMM PF00892; hypothetical protein complement(1263206..1263634) Brucella suis 1330 1166985 NP_698308.1 CDS cobO NC_004310.3 1263634 1264242 R catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide; cob(I)yrinic acid a,c-diamide adenosyltransferase complement(1263634..1264242) Brucella suis 1330 1166986 NP_698309.1 CDS cobN NC_004310.3 1264265 1268056 R with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; cobaltochelatase subunit CobN complement(1264265..1268056) Brucella suis 1330 1166987 NP_698310.1 CDS BR1307 NC_004310.3 1268056 1269105 R identified by match to protein family HMM PF02492; cobW protein complement(1268056..1269105) Brucella suis 1330 1166988 NP_698311.1 CDS cobU NC_004310.3 1269109 1269630 R catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP; adenosylcobinamide kinase complement(1269109..1269630) Brucella suis 1330 1166989 NP_698312.1 CDS BR1309 NC_004310.3 1269636 1270352 R identified by similarity to OMNI:NTL02ML1033; hypothetical protein complement(1269636..1270352) Brucella suis 1330 1166990 NP_698313.1 CDS BR1310 NC_004310.3 1270441 1270629 R identified by similarity to GP:14022104; hypothetical protein complement(1270441..1270629) Brucella suis 1330 1166991 NP_698314.1 CDS cobQ NC_004310.3 1270943 1272394 R catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation; cobyric acid synthase complement(1270943..1272394) Brucella suis 1330 1166992 NP_698315.1 CDS BR1312 NC_004310.3 1272405 1272554 R hypothetical protein complement(1272405..1272554) Brucella suis 1330 1166993 NP_698316.1 CDS mmsB NC_004310.3 1273859 1274749 D identified by match to protein family HMM PF03446; match to protein family HMM TIGR01692; 3-hydroxyisobutyrate dehydrogenase 1273859..1274749 Brucella suis 1330 1166995 NP_698317.1 CDS BR1315 NC_004310.3 1274985 1275152 R hypothetical protein complement(1274985..1275152) Brucella suis 1330 1166996 NP_698318.1 CDS BR1316 NC_004310.3 1275145 1275279 R identified by similarity to OMNI:CC3473; hypothetical protein complement(1275145..1275279) Brucella suis 1330 1166997 NP_698319.1 CDS BR1317 NC_004310.3 1275347 1275448 R hypothetical protein complement(1275347..1275448) Brucella suis 1330 1166998 NP_698320.1 CDS BR1319 NC_004310.3 1276826 1277824 D identified by match to protein family HMM PF00165; match to protein family HMM PF01965; AraC family transcriptional regulator 1276826..1277824 Brucella suis 1330 1167000 NP_698321.1 CDS BR1321 NC_004310.3 1280737 1281027 R identified by similarity to OMNI:NTL02ML1001; hypothetical protein complement(1280737..1281027) Brucella suis 1330 1167002 NP_698322.1 CDS BR1323 NC_004310.3 1283839 1284423 R hypothetical protein complement(1283839..1284423) Brucella suis 1330 1167004 NP_698323.1 CDS BR1324 NC_004310.3 1284475 1287012 D part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; bifunctional preprotein translocase subunit SecD/SecF 1284475..1287012 Brucella suis 1330 1167005 NP_698324.1 CDS BR1325 NC_004310.3 1287090 1288949 D identified by match to protein family HMM PF00999; match to protein family HMM PF02254; match to protein family HMM TIGR00932; potassium efflux system family protein 1287090..1288949 Brucella suis 1330 1167006 NP_698325.1 CDS BR1326 NC_004310.3 1288949 1289920 D hypothetical protein 1288949..1289920 Brucella suis 1330 1167007 NP_698326.1 CDS BR1327 NC_004310.3 1290147 1290752 D identified by similarity to GP:15074696; hypothetical protein 1290147..1290752 Brucella suis 1330 1167008 NP_698327.1 CDS cysW-2 NC_004310.3 1290798 1291628 R identified by similarity to SP:P16702; match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02140; sulfate ABC transporter permease complement(1290798..1291628) Brucella suis 1330 1167009 NP_698328.1 CDS BR1329 NC_004310.3 1291615 1292481 R identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139; sulfate ABC transporter permease complement(1291615..1292481) Brucella suis 1330 1167010 NP_698329.1 CDS BR1330 NC_004310.3 1292608 1293612 R identified by similarity to SP:P06997; match to protein family HMM PF01547; match to protein family HMM TIGR00971; sulfate ABC transporter sulfate-binding protein complement(1292608..1293612) Brucella suis 1330 1167011 NP_698330.1 CDS BR1331 NC_004310.3 1293878 1294063 R hypothetical protein complement(1293878..1294063) Brucella suis 1330 1167012 NP_698331.1 CDS BR1332 NC_004310.3 1294243 1295799 R identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741; CBS domain-containing protein complement(1294243..1295799) Brucella suis 1330 1167013 NP_698332.1 CDS BR1333 NC_004310.3 1296229 1296891 R identified by match to protein family HMM PF00597; dedA family protein complement(1296229..1296891) Brucella suis 1330 1167014 NP_698333.1 CDS BR1334 NC_004310.3 1296967 1297062 D hypothetical protein 1296967..1297062 Brucella suis 1330 1167015 NP_698334.1 CDS BR1335 NC_004310.3 1297299 1297505 D hypothetical protein 1297299..1297505 Brucella suis 1330 1167016 NP_698335.1 CDS BR1336 NC_004310.3 1297774 1298328 D identified by similarity to EGAD:154080; match to protein family HMM PF00036; acid-shock protein 1297774..1298328 Brucella suis 1330 1167018 NP_698336.1 CDS fucU NC_004310.3 1298462 1298884 R identified by match to protein family HMM PF05025; fucose operon fucU protein complement(1298462..1298884) Brucella suis 1330 1167019 NP_698337.1 CDS BR1338 NC_004310.3 1298978 1299787 R identified by similarity to OMNI:NTL02ML3842; match to protein family HMM PF00106; short chain dehydrogenase complement(1298978..1299787) Brucella suis 1330 1167020 NP_698338.1 CDS BR1339 NC_004310.3 1299802 1300581 R identified by match to protein family HMM PF00005; sugar ABC transporter ATP-binding protein complement(1299802..1300581) Brucella suis 1330 1167021 NP_698339.1 CDS BR1340 NC_004310.3 1300595 1301722 R identified by similarity to GP:6273663; match to protein family HMM PF02653; sugar ABC transporter permease complement(1300595..1301722) Brucella suis 1330 1167022 NP_698340.1 CDS BR1341 NC_004310.3 1301755 1301847 R hypothetical protein complement(1301755..1301847) Brucella suis 1330 1167023 NP_698341.1 CDS BR1342 NC_004310.3 1302009 1302938 R identified by similarity to GP:6273662; match to protein family HMM PF00532; sugar ABC transporter periplasmic sugar-binding protein complement(1302009..1302938) Brucella suis 1330 1167024 NP_698342.1 CDS BR1343 NC_004310.3 1303317 1304432 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; oxidoreductase 1303317..1304432 Brucella suis 1330 1167025 NP_698343.1 CDS BR1344 NC_004310.3 1304429 1305205 R identified by similarity to SP:P15031; match to protein family HMM PF00005; iron ABC transporter ATP-binding protein complement(1304429..1305205) Brucella suis 1330 1167026 NP_698344.1 CDS BR1345 NC_004310.3 1305202 1306203 R identified by match to protein family HMM PF01032; iron ABC transporter permease complement(1305202..1306203) Brucella suis 1330 1167027 NP_698345.1 CDS BR1346 NC_004310.3 1306196 1307035 R identified by similarity to PIR:S54437; match to protein family HMM PF01497; iron ABC transporter substrate-binding protein complement(1306196..1307035) Brucella suis 1330 1167028 NP_698346.1 CDS BR1347 NC_004310.3 1307049 1308911 R identified by similarity to SP:P06129; match to protein family HMM PF00593; iron compound TonB-dependent receptor complement(1307049..1308911) Brucella suis 1330 1167029 NP_698347.1 CDS BR1348 NC_004310.3 1309200 1309355 R hypothetical protein complement(1309200..1309355) Brucella suis 1330 1167030 NP_698348.1 CDS BR1349 NC_004310.3 1309405 1310517 R ABC transporter permease complement(1309405..1310517) Brucella suis 1330 1167031 NP_698349.1 CDS BR1350 NC_004310.3 1310519 1313287 R identified by match to protein family HMM PF00005; ABC transporter ATP binding/permease complement(1310519..1313287) Brucella suis 1330 1167032 NP_698350.1 CDS BR1351 NC_004310.3 1313284 1314351 R identified by match to protein family HMM PF00529; HlyD family secretion protein complement(1313284..1314351) Brucella suis 1330 1167033 NP_698351.1 CDS BR1352 NC_004310.3 1314331 1314510 D hypothetical protein 1314331..1314510 Brucella suis 1330 1167034 NP_698352.1 CDS BR1353 NC_004310.3 1314588 1314851 R hypothetical protein complement(1314588..1314851) Brucella suis 1330 1167035 NP_698353.1 CDS BR1354 NC_004310.3 1314896 1316191 R identified by similarity to OMNI:NTL02EC1981; match to protein family HMM PF02638; hypothetical protein complement(1314896..1316191) Brucella suis 1330 1167036 NP_698354.1 CDS BR1355 NC_004310.3 1316770 1316946 R hypothetical protein complement(1316770..1316946) Brucella suis 1330 1167037 NP_698355.1 CDS ureA NC_004310.3 1317006 1317308 D UreA, with UreB and UreC, catalyzes the hydrolysis of urea to ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 1317006..1317308 Brucella suis 1330 1167038 NP_698356.1 CDS ureB NC_004310.3 1317357 1317836 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) does not seem to be involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo; urease subunit beta 1317357..1317836 Brucella suis 1330 1167039 NP_698357.1 CDS ureC NC_004310.3 1317876 1319597 D ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 1317876..1319597 Brucella suis 1330 1167040 NP_698358.1 CDS ureE NC_004310.3 1319645 1320250 D involved in the assembly of the urease metallocenter; possible nickel donor; urease accessory protein UreE 1319645..1320250 Brucella suis 1330 1167041 NP_698359.1 CDS BR1360 NC_004310.3 1320222 1320953 D identified by similarity to EGAD:8726; match to protein family HMM PF01730; urease accessory protein UreF 1320222..1320953 Brucella suis 1330 1167042 NP_698360.1 CDS ureG-2 NC_004310.3 1320969 1321607 D identified by similarity to SP:P42871; match to protein family HMM PF01495; match to protein family HMM TIGR00101; urease accessory protein UreG 1320969..1321607 Brucella suis 1330 1167043 NP_698361.1 CDS ureD-2 NC_004310.3 1321607 1322515 D identified by similarity to EGAD:20614; match to protein family HMM PF01774; urease accessory protein UreD 1321607..1322515 Brucella suis 1330 1167044 NP_698362.1 CDS BR1363 NC_004310.3 1322525 1323577 D identified by similarity to GP:1905970; match to protein family HMM PF03253; urea transporter 1322525..1323577 Brucella suis 1330 1167045 NP_698363.1 CDS BR1364 NC_004310.3 1323604 1324362 D lipoprotein 1323604..1324362 Brucella suis 1330 1167046 NP_698364.1 CDS cbiM NC_004310.3 1324382 1325017 D catalyzes the ATP-dependent transport of cobalt; cobalt transport protein CbiM 1324382..1325017 Brucella suis 1330 1167047 NP_698365.1 CDS BR1366 NC_004310.3 1325014 1325640 D identified by similarity to EGAD:28613; hypothetical protein 1325014..1325640 Brucella suis 1330 1167048 NP_698366.1 CDS BR1367 NC_004310.3 1325637 1326401 D identified by similarity to GP:6138845; match to protein family HMM PF02361; cobalt ABC transporter permease 1325637..1326401 Brucella suis 1330 1167049 NP_698367.1 CDS BR1368 NC_004310.3 1326398 1327117 D identified by match to protein family HMM PF00005; cobalt ABC transporter ATP-binding protein 1326398..1327117 Brucella suis 1330 1167050 NP_698368.1 CDS BR1369 NC_004310.3 1327138 1327902 R identified by match to protein family HMM PF02537; match to protein family HMM PF03625; crcB family protein complement(1327138..1327902) Brucella suis 1330 1167051 NP_698369.1 CDS ccrB NC_004310.3 1327963 1328352 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1327963..1328352) Brucella suis 1330 1167052 NP_698370.1 CDS BR1371 NC_004310.3 1328621 1329646 D hypothetical protein 1328621..1329646 Brucella suis 1330 1167053 NP_698371.1 CDS BR1372 NC_004310.3 1329778 1330212 R identified by similarity to EGAD:6639; hypothetical protein complement(1329778..1330212) Brucella suis 1330 1167054 NP_698372.1 CDS BR1373 NC_004310.3 1330214 1330351 D hypothetical protein 1330214..1330351 Brucella suis 1330 1167055 NP_698373.1 CDS BR1374 NC_004310.3 1330364 1331290 R identified by similarity to EGAD:38480; match to protein family HMM PF02567; match to protein family HMM TIGR00654; PhzF family phenazine biosynthesis protein complement(1330364..1331290) Brucella suis 1330 1167056 NP_698374.1 CDS BR1375 NC_004310.3 1331395 1332057 R identified by similarity to OMNI:NTL02ML1103; hypothetical protein complement(1331395..1332057) Brucella suis 1330 1167057 NP_698375.1 CDS BR1377 NC_004310.3 1333258 1333773 D identified by similarity to GP:3236220; hypothetical protein 1333258..1333773 Brucella suis 1330 1167059 NP_698376.1 CDS BR1378 NC_004310.3 1333819 1335051 R identified by match to protein family HMM PF00155; class I aminotransferase complement(1333819..1335051) Brucella suis 1330 1167060 NP_698377.1 CDS BR1379 NC_004310.3 1335133 1335414 R hypothetical protein complement(1335133..1335414) Brucella suis 1330 1167061 NP_698378.1 CDS ilvC NC_004310.3 1335436 1336455 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(1335436..1336455) Brucella suis 1330 1167062 NP_698379.1 CDS BR1381 NC_004310.3 1336511 1337152 R identified by match to protein family HMM PF00440; TetR family transcriptional regulator complement(1336511..1337152) Brucella suis 1330 1167063 NP_698380.1 CDS BR1382 NC_004310.3 1337210 1337365 D hypothetical protein 1337210..1337365 Brucella suis 1330 1167064 NP_698381.1 CDS BR1383 NC_004310.3 1337362 1339317 R identified by similarity to SP:P30016; match to protein family HMM PF02705; potassium uptake protein complement(1337362..1339317) Brucella suis 1330 1167065 NP_698382.1 CDS BR1384 NC_004310.3 1339460 1339618 R hypothetical protein complement(1339460..1339618) Brucella suis 1330 1167066 NP_698383.1 CDS BR1385 NC_004310.3 1339687 1340427 R involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase complement(1339687..1340427) Brucella suis 1330 1167067 NP_698384.1 CDS BR1386 NC_004310.3 1340724 1341125 D hypothetical protein 1340724..1341125 Brucella suis 1330 1167068 NP_698385.1 CDS BR1387 NC_004310.3 1341126 1342247 R identified by similarity to OMNI:NTL02ML1120; hypothetical protein complement(1341126..1342247) Brucella suis 1330 1167069 NP_698386.1 CDS ilvH NC_004310.3 1342431 1343003 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit complement(1342431..1343003) Brucella suis 1330 1167070 NP_698387.1 CDS ilvB NC_004310.3 1343022 1344776 R catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; acetolactate synthase 3 catalytic subunit complement(1343022..1344776) Brucella suis 1330 1167071 NP_698388.1 CDS miaA NC_004310.3 1345093 1346025 R IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase complement(1345093..1346025) Brucella suis 1330 1167072 NP_698389.1 CDS serB NC_004310.3 1346043 1346942 D identified by match to protein family HMM PF00702; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488; phosphoserine phosphatase 1346043..1346942 Brucella suis 1330 1167073 NP_698390.1 CDS BR1392 NC_004310.3 1346983 1348164 R identified by similarity to OMNI:CC1477; match to protein family HMM PF03486; match to protein family HMM TIGR00275; hypothetical protein complement(1346983..1348164) Brucella suis 1330 1167074 NP_698391.1 CDS BR1393 NC_004310.3 1348140 1348283 R hypothetical protein complement(1348140..1348283) Brucella suis 1330 1167075 NP_698392.1 CDS BR1394 NC_004310.3 1348294 1349868 R identified by similarity to OMNI:CC2758; match to protein family HMM PF00089; match to protein family HMM PF00595; serine protease Do complement(1348294..1349868) Brucella suis 1330 1167076 NP_698393.1 CDS BR1395 NC_004310.3 1350092 1350277 R identified by similarity to GP:14022214; hypothetical protein complement(1350092..1350277) Brucella suis 1330 1167077 NP_698394.1 CDS hflC NC_004310.3 1350297 1351199 R identified by similarity to EGAD:9363; match to protein family HMM PF01145; match to protein family HMM TIGR01932; hflC protein complement(1350297..1351199) Brucella suis 1330 1167078 NP_698395.1 CDS hflK NC_004310.3 1351199 1352347 R identified by similarity to SP:Q9KV09; match to protein family HMM PF01145; match to protein family HMM TIGR01933; hflK protein complement(1351199..1352347) Brucella suis 1330 1167079 NP_698396.1 CDS folA NC_004310.3 1352472 1352990 R identified by match to protein family HMM PF00186; dihydrofolate reductase complement(1352472..1352990) Brucella suis 1330 1167080 NP_698397.1 CDS thyA NC_004310.3 1352993 1353787 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(1352993..1353787) Brucella suis 1330 1167081 NP_698398.1 CDS BR1400 NC_004310.3 1353888 1354199 R identified by similarity to OMNI:NTL02ML1156; hypothetical protein complement(1353888..1354199) Brucella suis 1330 1167082 NP_698399.1 CDS tcaB NC_004310.3 1354772 1355983 R identified by match to protein family HMM PF00083; match to protein family HMM TIGR00710; Bcr/CflA subfamily drug resistance transporter complement(1354772..1355983) Brucella suis 1330 1167083 NP_698400.1 CDS BR1402 NC_004310.3 1356000 1356146 R hypothetical protein complement(1356000..1356146) Brucella suis 1330 1167084 NP_698401.1 CDS BR1403 NC_004310.3 1356278 1357003 D identified by match to protein family HMM PF00440; TetR family transcriptional regulator 1356278..1357003 Brucella suis 1330 1167085 NP_698402.1 CDS BR1404 NC_004310.3 1357084 1357653 D identified by similarity to OMNI:NTL02ML1160; hypothetical protein 1357084..1357653 Brucella suis 1330 1167086 NP_698403.1 CDS BR1405 NC_004310.3 1357766 1357942 D hypothetical protein 1357766..1357942 Brucella suis 1330 1167087 NP_698404.1 CDS BR1406 NC_004310.3 1358034 1358234 D identified by similarity to OMNI:NTL02ML1161; hypothetical protein 1358034..1358234 Brucella suis 1330 1167088 NP_698405.1 CDS BR1407 NC_004310.3 1358231 1358482 D identified by similarity to OMNI:NTL02ML1162; hypothetical protein 1358231..1358482 Brucella suis 1330 1167089 NP_698406.1 CDS BR1408 NC_004310.3 1358510 1362253 R identified by similarity to OMNI:NTL02ML1167; match to protein family HMM PF05170; hypothetical protein complement(1358510..1362253) Brucella suis 1330 1167090 NP_698407.1 CDS BR1409 NC_004310.3 1362308 1362448 R hypothetical protein complement(1362308..1362448) Brucella suis 1330 1167091 NP_698408.1 CDS BR1410 NC_004310.3 1362445 1363851 R identified by match to protein family HMM PF01565; match to protein family HMM PF02913; FAD-binding oxidoreductase complement(1362445..1363851) Brucella suis 1330 1167092 NP_698409.1 CDS BR1411 NC_004310.3 1363876 1364385 R identified by similarity to OMNI:NTL02ML3966; hypothetical protein complement(1363876..1364385) Brucella suis 1330 1167093 NP_698410.1 CDS BR1412 NC_004310.3 1364505 1365581 D identified by similarity to OMNI:NTL01XF00279; serine/threonine protein kinase 1364505..1365581 Brucella suis 1330 1167094 NP_698411.1 CDS BR1413 NC_004310.3 1365640 1368216 D identified by similarity to EGAD:14237; match to protein family HMM PF00580; DNA helicase II 1365640..1368216 Brucella suis 1330 1167095 NP_698412.1 CDS BR1414 NC_004310.3 1368290 1368787 R identified by similarity to GP:14022272; hypothetical protein complement(1368290..1368787) Brucella suis 1330 1167096 NP_698413.1 CDS BR1415 NC_004310.3 1368852 1369541 R identified by similarity to OMNI:NTL02ML1201; match to protein family HMM PF00132; antibiotic acetyltransferase complement(1368852..1369541) Brucella suis 1330 1167097 NP_698414.1 CDS BR1416 NC_004310.3 1369650 1370240 D identified by match to protein family HMM PF02630; SCO1/SenC family protein 1369650..1370240 Brucella suis 1330 1167098 NP_698415.1 CDS prmA NC_004310.3 1370278 1371135 D methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 1370278..1371135 Brucella suis 1330 1167099 NP_698416.1 CDS BR1418 NC_004310.3 1371201 1373027 D identified by similarity to OMNI:NTL02ML1206; match to protein family HMM PF00557; aminopeptidase 1371201..1373027 Brucella suis 1330 1167100 NP_698417.1 CDS BR1419 NC_004310.3 1373028 1373732 R identified by similarity to GP:14022279; hypothetical protein complement(1373028..1373732) Brucella suis 1330 1167101 NP_698418.1 CDS ligA NC_004310.3 1373732 1375891 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1373732..1375891) Brucella suis 1330 1167102 NP_698419.1 CDS recN NC_004310.3 1376077 1377756 R identified by similarity to SP:P05824; match to protein family HMM TIGR00634; DNA repair protein RecN complement(1376077..1377756) Brucella suis 1330 1167103 NP_698420.1 CDS BR1422 NC_004310.3 1377769 1378632 R identified by similarity to EGAD:40678; match to protein family HMM PF03696; competence protein ComL complement(1377769..1378632) Brucella suis 1330 1167104 NP_698421.1 CDS BR1423 NC_004310.3 1378716 1378979 D hypothetical protein 1378716..1378979 Brucella suis 1330 1167105 NP_698422.1 CDS lpxC NC_004310.3 1379039 1379899 R zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis; UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase complement(1379039..1379899) Brucella suis 1330 1167106 NP_698423.1 CDS ftsZ NC_004310.3 1380439 1382139 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1380439..1382139) Brucella suis 1330 1167107 NP_698424.1 CDS ftsA NC_004310.3 1382236 1383558 R identified by similarity to SP:O30994; match to protein family HMM PF02491; match to protein family HMM TIGR01174; cell division protein FtsA complement(1382236..1383558) Brucella suis 1330 1167108 NP_698425.1 CDS BR1427 NC_004310.3 1383555 1384421 R identified by similarity to SP:O30993; match to protein family HMM PF03799; cell division protein FtsQ complement(1383555..1384421) Brucella suis 1330 1167109 NP_698426.1 CDS ddl NC_004310.3 1384478 1385404 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase complement(1384478..1385404) Brucella suis 1330 1167110 NP_698427.1 CDS murB NC_004310.3 1385647 1386615 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1385647..1386615) Brucella suis 1330 1167111 NP_698428.1 CDS murC NC_004310.3 1386615 1388030 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1386615..1388030) Brucella suis 1330 1167112 NP_698429.1 CDS murG NC_004310.3 1388027 1389166 R UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase complement(1388027..1389166) Brucella suis 1330 1167113 NP_698430.1 CDS ftsW NC_004310.3 1389393 1390550 R identified by similarity to EGAD:20048; match to protein family HMM PF01098; cell division protein FtsW complement(1389393..1390550) Brucella suis 1330 1167114 NP_698431.1 CDS murD NC_004310.3 1390550 1391953 R UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase complement(1390550..1391953) Brucella suis 1330 1167115 NP_698432.1 CDS mraY NC_004310.3 1391966 1393048 R First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase complement(1391966..1393048) Brucella suis 1330 1167116 NP_698433.1 CDS murF NC_004310.3 1393075 1394520 R identified by similarity to EGAD:15807; match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM TIGR01143; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase complement(1393075..1394520) Brucella suis 1330 1167117 NP_698434.1 CDS murE NC_004310.3 1394517 1395983 R involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase complement(1394517..1395983) Brucella suis 1330 1167118 NP_698435.1 CDS BR1437 NC_004310.3 1396044 1397867 R identified by match to protein family HMM PF00905; match to protein family HMM PF03717; penicillin-binding protein complement(1396044..1397867) Brucella suis 1330 1167119 NP_698436.1 CDS BR1438 NC_004310.3 1397870 1398271 R identified by similarity to GP:14022298; hypothetical protein complement(1397870..1398271) Brucella suis 1330 1167120 NP_698437.1 CDS mraW NC_004310.3 1398276 1399316 R identified by similarity to GP:15075206; match to protein family HMM PF01795; match to protein family HMM TIGR00006; S-adenosyl-methyltransferase MraW complement(1398276..1399316) Brucella suis 1330 1167121 NP_698438.1 CDS BR1440 NC_004310.3 1399294 1399563 D hypothetical protein 1399294..1399563 Brucella suis 1330 1167122 NP_698439.1 CDS BR1441 NC_004310.3 1399774 1401144 D identified by similarity to GP:17740175; match to protein family HMM PF01566; match to protein family HMM TIGR01197; manganese transport protein MntH 1399774..1401144 Brucella suis 1330 1167123 NP_698440.1 CDS BR1442 NC_004310.3 1401337 1401849 D hypothetical protein 1401337..1401849 Brucella suis 1330 1167124 NP_698441.1 CDS BR1443 NC_004310.3 1401846 1402490 R identified by match to protein family HMM PF01464; transglycosylase SLT domain-containing protein complement(1401846..1402490) Brucella suis 1330 1167125 NP_698442.1 CDS BR1444 NC_004310.3 1402831 1403637 R identified by match to protein family HMM PF01471; match to protein family HMM PF01510; N-acetylmuramoyl-L-alanine amidase complement(1402831..1403637) Brucella suis 1330 1167126 NP_698443.1 CDS BR1445 NC_004310.3 1403634 1404344 R identified by match to protein family HMM PF00226; DnaJ domain-containing protein complement(1403634..1404344) Brucella suis 1330 1167127 NP_698444.1 CDS BR1446 NC_004310.3 1404464 1404868 R hypothetical protein complement(1404464..1404868) Brucella suis 1330 1167128 NP_698445.1 CDS BR1447 NC_004310.3 1405172 1406005 D identified by match to protein family HMM PF01183; glycosyl hydrolase 1405172..1406005 Brucella suis 1330 1167129 NP_698446.1 CDS metF NC_004310.3 1408788 1409699 R identified by match to protein family HMM PF02219; match to protein family HMM TIGR00676; 5,10-methylenetetrahydrofolate reductase complement(1408788..1409699) Brucella suis 1330 1167132 NP_698447.1 CDS BR1451 NC_004310.3 1409745 1410770 R identified by match to protein family HMM PF01022; match to protein family HMM PF01209; ArsR family transcriptional regulator complement(1409745..1410770) Brucella suis 1330 1167133 NP_698448.1 CDS BR1452 NC_004310.3 1410890 1411213 D identified by similarity to OMNI:NTL02ML1250; hypothetical protein 1410890..1411213 Brucella suis 1330 1167134 NP_698449.1 CDS BR1453 NC_004310.3 1411268 1412593 R identified by match to protein family HMM PF00083; match to protein family HMM TIGR00883; metabolite-proton symporter complement(1411268..1412593) Brucella suis 1330 1167135 NP_698450.1 CDS BR1454 NC_004310.3 1412601 1412855 D hypothetical protein 1412601..1412855 Brucella suis 1330 1167136 NP_698451.1 CDS tam NC_004310.3 1413029 1413796 R catalyzes the formation of (E)-3-(methoxycarbonyl)pent-2-enedioate and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and trans-aconitate; trans-aconitate 2-methyltransferase complement(1413029..1413796) Brucella suis 1330 1167137 NP_698452.1 CDS BR1456 NC_004310.3 1413869 1415518 R ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; ABC transporter ATP-binding protein complement(1413869..1415518) Brucella suis 1330 1167138 NP_698453.1 CDS BR1457 NC_004310.3 1415598 1415777 R hypothetical protein complement(1415598..1415777) Brucella suis 1330 1167139 NP_698454.1 CDS BR1458 NC_004310.3 1416014 1416958 D identified by similarity to OMNI:NTL02ML1266; hypothetical protein 1416014..1416958 Brucella suis 1330 1167140 NP_698455.1 CDS BR1459 NC_004310.3 1416997 1417662 D hypothetical protein 1416997..1417662 Brucella suis 1330 1167141 NP_698456.1 CDS BR1460 NC_004310.3 1417756 1418442 R identified by similarity to OMNI:NTL01PM1376; hypothetical protein complement(1417756..1418442) Brucella suis 1330 1167142 NP_698457.1 CDS BR1461 NC_004310.3 1418823 1420040 D identified by match to protein family HMM PF00355; Rieske 2Fe-2S family protein 1418823..1420040 Brucella suis 1330 1167143 NP_698458.1 CDS BR1462 NC_004310.3 1420074 1421192 D identified by similarity to EGAD:91746; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; NADH oxidoreductase 1420074..1421192 Brucella suis 1330 1167144 NP_698459.1 CDS BR1463 NC_004310.3 1421206 1421415 R identified by similarity to SP:P16680; match to protein family HMM PF03831; phnA protein complement(1421206..1421415) Brucella suis 1330 1167145 NP_698460.1 CDS pncA NC_004310.3 1421553 1422182 D identified by similarity to SP:P21369; match to protein family HMM PF00857; pyrazinamidase/nicotinamidase 1421553..1422182 Brucella suis 1330 1167146 NP_698461.1 CDS BR1465 NC_004310.3 1422179 1423240 R identified by match to protein family HMM PF04332; hypothetical protein complement(1422179..1423240) Brucella suis 1330 1167147 NP_698462.1 CDS BR1466 NC_004310.3 1423587 1423853 D hypothetical protein 1423587..1423853 Brucella suis 1330 1167148 NP_698463.1 CDS BR1467 NC_004310.3 1423809 1423988 R hypothetical protein complement(1423809..1423988) Brucella suis 1330 1167149 NP_698464.1 CDS BR1468 NC_004310.3 1424051 1425052 R identified by match to protein family HMM PF02275; choloylglycine hydrolase complement(1424051..1425052) Brucella suis 1330 1167150 NP_698465.1 CDS BR1469 NC_004310.3 1425430 1426233 D identified by similarity to GP:14523684; hypothetical protein 1425430..1426233 Brucella suis 1330 1167151 NP_698466.1 CDS BR1470 NC_004310.3 1426840 1427013 D hypothetical protein 1426840..1427013 Brucella suis 1330 1167152 NP_698467.1 CDS BR1471 NC_004310.3 1427067 1427294 R hypothetical protein complement(1427067..1427294) Brucella suis 1330 1167153 NP_698468.1 CDS BR1472 NC_004310.3 1427421 1427774 D hypothetical protein 1427421..1427774 Brucella suis 1330 1167154 NP_698469.1 CDS BR1473 NC_004310.3 1427935 1428507 R hypothetical protein complement(1427935..1428507) Brucella suis 1330 1167155 NP_698470.1 CDS BR1474 NC_004310.3 1428743 1429237 D identified by match to protein family HMM PF00589; phage integrase site specific recombinase 1428743..1429237 Brucella suis 1330 1167156 NP_698471.1 CDS omp28 NC_004310.3 1429655 1430407 D identified by similarity to EGAD:40996; match to protein family HMM PF04402; hypothetical protein 1429655..1430407 Brucella suis 1330 1167158 NP_698472.1 CDS BR1476 NC_004310.3 1430582 1430926 R hypothetical protein complement(1430582..1430926) Brucella suis 1330 1167159 NP_698473.1 CDS BR1477 NC_004310.3 1431170 1431628 R identified by similarity to OMNI:NTL02ML1869; match to protein family HMM PF05779; hypothetical protein complement(1431170..1431628) Brucella suis 1330 1167160 NP_698474.1 CDS BR1478 NC_004310.3 1431820 1432110 R identified by similarity to OMNI:NTL02ML1900; hypothetical protein complement(1431820..1432110) Brucella suis 1330 1167161 NP_698475.1 CDS rpoD NC_004310.3 1432134 1434152 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD complement(1432134..1434152) Brucella suis 1330 1167162 NP_698476.1 CDS dnaG NC_004310.3 1434620 1436587 R synthesizes RNA primers at the replication forks; DNA primase complement(1434620..1436587) Brucella suis 1330 1167163 NP_698477.1 CDS BR1481 NC_004310.3 1436957 1438633 D identified by match to protein family HMM PF02690; Na/Pi-cotransporter family protein 1436957..1438633 Brucella suis 1330 1167164 NP_698478.1 CDS BR1482 NC_004310.3 1438700 1439152 R identified by similarity to GP:15075342; match to protein family HMM PF02637; hypothetical protein complement(1438700..1439152) Brucella suis 1330 1167165 NP_698479.1 CDS carA NC_004310.3 1439532 1440755 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 1439532..1440755 Brucella suis 1330 1167166 NP_698480.1 CDS BR1484 NC_004310.3 1440763 1440891 D hypothetical protein 1440763..1440891 Brucella suis 1330 1167167 NP_698481.1 CDS BR1485 NC_004310.3 1440927 1441853 R identified by similarity to GP:15074511; match to protein family HMM PF04228; hypothetical protein complement(1440927..1441853) Brucella suis 1330 1167168 NP_698482.1 CDS BR1486 NC_004310.3 1441970 1442488 R identified by similarity to GP:15157321; hypothetical protein complement(1441970..1442488) Brucella suis 1330 1167169 NP_698483.1 CDS BR1487 NC_004310.3 1442502 1443374 D identified by similarity to GP:15157322; match to protein family HMM PF04397; hypothetical protein 1442502..1443374 Brucella suis 1330 1167170 NP_698484.1 CDS carB NC_004310.3 1443609 1447097 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 1443609..1447097 Brucella suis 1330 1167171 NP_698485.1 CDS BR1489 NC_004310.3 1447418 1447756 D hypothetical protein 1447418..1447756 Brucella suis 1330 1167172 NP_698486.1 CDS BR1490 NC_004310.3 1447814 1449679 R identified by similarity to GP:2808503; transporter complement(1447814..1449679) Brucella suis 1330 1167173 NP_698487.1 CDS BR1491 NC_004310.3 1449869 1450330 D identified by match to protein family HMM PF00293; MutT/nudix family protein 1449869..1450330 Brucella suis 1330 1167174 NP_698488.1 CDS BR1492 NC_004310.3 1450523 1450732 D identified by similarity to SP:Q9Z3S6; match to protein family HMM PF00313; cold-shock family protein 1450523..1450732 Brucella suis 1330 1167175 NP_698489.1 CDS BR1493 NC_004310.3 1450862 1451473 R identified by match to protein family HMM PF00043; match to protein family HMM PF02798; glutathione S-transferase complement(1450862..1451473) Brucella suis 1330 1167176 NP_698490.1 CDS BR1494 NC_004310.3 1451596 1451724 R hypothetical protein complement(1451596..1451724) Brucella suis 1330 1167177 NP_698491.1 CDS aspC NC_004310.3 1451723 1452925 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1451723..1452925 Brucella suis 1330 1167178 NP_698492.1 CDS BR1496 NC_004310.3 1452945 1453052 D hypothetical protein 1452945..1453052 Brucella suis 1330 1167179 NP_698493.1 CDS BR1497 NC_004310.3 1453128 1453343 D hypothetical protein 1453128..1453343 Brucella suis 1330 1167180 NP_698494.1 CDS BR1498 NC_004310.3 1453395 1454300 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1453395..1454300) Brucella suis 1330 1167181 NP_698495.1 CDS trxB NC_004310.3 1454371 1455345 R identified by similarity to SP:P09625; match to protein family HMM PF00070; match to protein family HMM TIGR01292; thioredoxin reductase complement(1454371..1455345) Brucella suis 1330 1167182 NP_698496.1 CDS BR1500 NC_004310.3 1455667 1457067 D identified by similarity to GP:3288671; match to protein family HMM PF02386; cation transport protein 1455667..1457067 Brucella suis 1330 1167183 NP_698497.1 CDS BR1501 NC_004310.3 1457074 1457238 D hypothetical protein 1457074..1457238 Brucella suis 1330 1167184 NP_698498.1 CDS lrp-1 NC_004310.3 1457325 1457795 D identified by similarity to SP:P56901; match to protein family HMM PF01037; leucine-responsive regulatory protein 1457325..1457795 Brucella suis 1330 1167185 NP_698499.1 CDS lpcC NC_004310.3 1457802 1458866 R identified by similarity to SP:O68547; match to protein family HMM PF00534; lipopolysaccharide core biosynthesis mannosyltransferase LpcC complement(1457802..1458866) Brucella suis 1330 1167186 NP_698500.1 CDS greA NC_004310.3 1458873 1459346 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1458873..1459346) Brucella suis 1330 1167187 NP_698501.1 CDS BR1505 NC_004310.3 1459615 1460634 R identified by similarity to EGAD:91665; hypothetical protein complement(1459615..1460634) Brucella suis 1330 1167188 NP_698502.1 CDS BR1506 NC_004310.3 1460660 1460848 R hypothetical protein complement(1460660..1460848) Brucella suis 1330 1167189 NP_698503.1 CDS BR1507 NC_004310.3 1460826 1461737 D identified by match to protein family HMM PF00892; hypothetical protein 1460826..1461737 Brucella suis 1330 1167190 NP_698504.1 CDS BR1508 NC_004310.3 1461742 1462092 R identified by match to protein family HMM PF04342; hypothetical protein complement(1461742..1462092) Brucella suis 1330 1167191 NP_698505.1 CDS BR1509 NC_004310.3 1462370 1463281 D identified by similarity to GP:15074829; hypothetical protein 1462370..1463281 Brucella suis 1330 1167192 NP_698506.1 CDS BR1510 NC_004310.3 1463414 1463803 R identified by match to protein family HMM PF03061; long-chain acyl-CoA thioester hydrolase complement(1463414..1463803) Brucella suis 1330 1167193 NP_698507.1 CDS BR1511 NC_004310.3 1464025 1464606 D identified by similarity to GP:15162152; hypothetical protein 1464025..1464606 Brucella suis 1330 1167194 NP_698508.1 CDS uvrB NC_004310.3 1464732 1467554 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1464732..1467554 Brucella suis 1330 1167195 NP_698509.1 CDS BR1514 NC_004310.3 1468984 1469199 D identified by match to protein family HMM PF00313; cold-shock family protein 1468984..1469199 Brucella suis 1330 1167197 NP_698510.1 CDS BR1515 NC_004310.3 1469437 1469556 R hypothetical protein complement(1469437..1469556) Brucella suis 1330 1167198 NP_698511.1 CDS BR1516 NC_004310.3 1469616 1470125 D identified by similarity to GP:15075354; hypothetical protein 1469616..1470125 Brucella suis 1330 1167199 NP_698512.1 CDS BR1517 NC_004310.3 1470184 1470840 R identified by match to protein family HMM PF00753; metallo-beta-lactamase complement(1470184..1470840) Brucella suis 1330 1167200 NP_698513.1 CDS BR1518 NC_004310.3 1471054 1471335 R hypothetical protein complement(1471054..1471335) Brucella suis 1330 1167201 NP_698514.1 CDS BR1519 NC_004310.3 1471507 1471806 D hypothetical protein 1471507..1471806 Brucella suis 1330 1167202 NP_698515.1 CDS BR1520 NC_004310.3 1471857 1472396 D identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1471857..1472396 Brucella suis 1330 1167203 NP_698516.1 CDS BR1521 NC_004310.3 1472478 1473203 D identified by similarity to EGAD:19467; match to protein family HMM PF00072; match to protein family HMM PF00486; transcriptional regulatory protein OmpR 1472478..1473203 Brucella suis 1330 1167204 NP_698517.1 CDS BR1522 NC_004310.3 1473392 1474690 D identified by similarity to EGAD:163236; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; osmolarity sensor protein EnvZ 1473392..1474690 Brucella suis 1330 1167205 NP_698518.1 CDS BR1523 NC_004310.3 1475022 1475141 R hypothetical protein complement(1475022..1475141) Brucella suis 1330 1167206 NP_698519.1 CDS csaA NC_004310.3 1475122 1475469 R identified by similarity to SP:P37584; match to protein family HMM PF01588; csaA protein complement(1475122..1475469) Brucella suis 1330 1167207 NP_698520.1 CDS BR1525 NC_004310.3 1475608 1476270 R identified by similarity to OMNI:NTL02ML2065; hypothetical protein complement(1475608..1476270) Brucella suis 1330 1167208 NP_698521.1 CDS BR1526 NC_004310.3 1476537 1476857 R identified by similarity to GP:15075365; match to protein family HMM PF04380; hypothetical protein complement(1476537..1476857) Brucella suis 1330 1167209 NP_698522.1 CDS BR1527 NC_004310.3 1476875 1477027 R hypothetical protein complement(1476875..1477027) Brucella suis 1330 1167210 NP_698523.1 CDS lgt NC_004310.3 1477042 1477887 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1477042..1477887 Brucella suis 1330 1167211 NP_698524.1 CDS BR1529 NC_004310.3 1477880 1478977 D identified by similarity to OMNI:NTL02ML2069; match to protein family HMM PF02636; hypothetical protein 1477880..1478977 Brucella suis 1330 1167212 NP_698525.1 CDS BR1530 NC_004310.3 1479157 1480008 D identified by similarity to OMNI:NTL02ML2070; match to protein family HMM PF02578; match to protein family HMM TIGR00726; hypothetical protein 1479157..1480008 Brucella suis 1330 1167213 NP_698526.1 CDS BR1531 NC_004310.3 1480121 1481272 D identified by match to protein family HMM PF00557; M24 family peptidase 1480121..1481272 Brucella suis 1330 1167214 NP_698527.1 CDS BR1532 NC_004310.3 1481326 1481880 D identified by similarity to GP:15075370; lipoprotein 1481326..1481880 Brucella suis 1330 1167215 NP_698528.1 CDS prsA NC_004310.3 1482219 1483151 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1482219..1483151 Brucella suis 1330 1167216 NP_698529.1 CDS BR1534 NC_004310.3 1483299 1484840 R identified by similarity to GP:15074722; hypothetical protein complement(1483299..1484840) Brucella suis 1330 1167217 NP_698530.1 CDS BR1535 NC_004310.3 1485532 1486155 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 1485532..1486155 Brucella suis 1330 1167218 NP_698531.1 CDS pth NC_004310.3 1486184 1486936 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1486184..1486936 Brucella suis 1330 1167219 NP_698532.1 CDS BR1537 NC_004310.3 1487024 1488127 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1487024..1488127 Brucella suis 1330 1167220 NP_698533.1 CDS BR1538 NC_004310.3 1488189 1488689 D identified by match to protein family HMM PF01575; acyl dehydratase MaoC 1488189..1488689 Brucella suis 1330 1167221 NP_698534.1 CDS BR1539 NC_004310.3 1488686 1489168 D identified by match to protein family HMM PF01575; acyl dehydratase MaoC 1488686..1489168 Brucella suis 1330 1167222 NP_698535.1 CDS apt NC_004310.3 1489210 1489770 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1489210..1489770) Brucella suis 1330 1167223 NP_698536.1 CDS BR1541 NC_004310.3 1490078 1490965 R identified by match to protein family HMM PF02167; ubiquinol-cytochrome c reductase, cytochrome c1 complement(1490078..1490965) Brucella suis 1330 1167224 NP_698537.1 CDS petB NC_004310.3 1490979 1492277 R identified by similarity to EGAD:46867; match to protein family HMM PF00032; match to protein family HMM PF00033; ubiquinol-cytochrome c reductase, cytochrome b complement(1490979..1492277) Brucella suis 1330 1167225 NP_698538.1 CDS BR1543 NC_004310.3 1492299 1492862 R identified by similarity to EGAD:9907; match to protein family HMM PF00355; match to protein family HMM TIGR01409; match to protein family HMM TIGR01416; ubiquinol-cytochrome c reductase, iron-sulfur subunit complement(1492299..1492862) Brucella suis 1330 1167226 NP_698539.1 CDS BR1546 NC_004310.3 1497151 1497630 D identified by match to protein family HMM PF00588; RNA methyltransferase 1497151..1497630 Brucella suis 1330 1167229 NP_698540.1 CDS BR1548 NC_004310.3 1498780 1498881 R hypothetical protein complement(1498780..1498881) Brucella suis 1330 1167231 NP_698541.1 CDS BR1549 NC_004310.3 1498889 1499149 R identified by similarity to GP:15074760; hypothetical protein complement(1498889..1499149) Brucella suis 1330 1167232 NP_698542.1 CDS hemF NC_004310.3 1499443 1500354 D catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 1499443..1500354 Brucella suis 1330 1167233 NP_698543.1 CDS BR1551 NC_004310.3 1500388 1500882 R identified by match to protein family HMM PF00583; acetyltransferase complement(1500388..1500882) Brucella suis 1330 1167234 NP_698544.1 CDS BR1553 NC_004310.3 1501915 1503186 R identified by match to protein family HMM PF01743; poly(A) polymerase complement(1501915..1503186) Brucella suis 1330 1167236 NP_698545.1 CDS BR1554 NC_004310.3 1503183 1503689 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(1503183..1503689) Brucella suis 1330 1167237 NP_698546.1 CDS BR1555 NC_004310.3 1503803 1504468 R identified by similarity to OMNI:NTL02ML2109; hypothetical protein complement(1503803..1504468) Brucella suis 1330 1167238 NP_698547.1 CDS moxR NC_004310.3 1504588 1505595 D identified by similarity to GP:2689172; moxR protein 1504588..1505595 Brucella suis 1330 1167239 NP_698548.1 CDS BR1557 NC_004310.3 1505595 1506527 D identified by similarity to OMNI:NTL02ML2111; match to protein family HMM PF01882; hypothetical protein 1505595..1506527 Brucella suis 1330 1167240 NP_698549.1 CDS BR1558 NC_004310.3 1506524 1509373 D hypothetical protein 1506524..1509373 Brucella suis 1330 1167241 NP_698550.1 CDS BR1559 NC_004310.3 1509437 1511512 D identified by similarity to OMNI:NTL02ML2113; hypothetical protein 1509437..1511512 Brucella suis 1330 1167242 NP_698551.1 CDS BR1560 NC_004310.3 1511580 1512086 R identified by match to protein family HMM PF00583; acetyltransferase complement(1511580..1512086) Brucella suis 1330 1167243 NP_698552.1 CDS BR1561 NC_004310.3 1512390 1513373 D glutathione S-transferase domain-containing protein 1512390..1513373 Brucella suis 1330 1167244 NP_698553.1 CDS BR1562 NC_004310.3 1513521 1514204 D identified by match to protein family HMM PF03922; hypothetical protein 1513521..1514204 Brucella suis 1330 1167245 NP_698554.1 CDS BR1563 NC_004310.3 1514238 1514693 R identified by match to protein family HMM PF00293; MutT/nudix family protein complement(1514238..1514693) Brucella suis 1330 1167246 NP_698555.1 CDS BR1564 NC_004310.3 1514802 1515704 D identified by similarity to GP:14023230; match to protein family HMM PF00149; hypothetical protein 1514802..1515704 Brucella suis 1330 1167247 NP_698556.1 CDS BR1565 NC_004310.3 1515698 1515826 R hypothetical protein complement(1515698..1515826) Brucella suis 1330 1167248 NP_698557.2 CDS leuA NC_004310.3 1515905 1517572 R identified by match to protein family HMM PF00682; match to protein family HMM TIGR00970; 2-isopropylmalate synthase complement(1515905..1517572) Brucella suis 1330 1167249 NP_698558.1 CDS BR1567 NC_004310.3 1517764 1517922 R hypothetical protein complement(1517764..1517922) Brucella suis 1330 1167250 NP_698559.1 CDS BR1568 NC_004310.3 1517937 1518845 R identified by similarity to GP:14023215; match to protein family HMM PF01545; match to protein family HMM TIGR01297; cation efflux family protein complement(1517937..1518845) Brucella suis 1330 1167251 NP_698560.1 CDS BR1569 NC_004310.3 1518855 1519136 D hypothetical protein 1518855..1519136 Brucella suis 1330 1167252 NP_698561.1 CDS trpE NC_004310.3 1519315 1521510 R trpE(G); catalyzes the formation of anthranilate from chorismate and glutamine; contains both component I and II; anthranilate synthase complement(1519315..1521510) Brucella suis 1330 1167253 NP_698562.1 CDS lrp-2 NC_004310.3 1522189 1522650 D identified by similarity to SP:P19494; match to protein family HMM PF01037; leucine-responsive regulatory protein 1522189..1522650 Brucella suis 1330 1167254 NP_698563.1 CDS BR1572 NC_004310.3 1522791 1523201 D identified by match to protein family HMM PF01047; MarR family transcriptional regulator 1522791..1523201 Brucella suis 1330 1167255 NP_698564.1 CDS BR1573 NC_004310.3 1523296 1524588 D identified by similarity to GP:17430574; transporter 1523296..1524588 Brucella suis 1330 1167256 NP_698565.1 CDS BR1574 NC_004310.3 1524583 1525548 R identified by similarity to GP:14027266; hypothetical protein complement(1524583..1525548) Brucella suis 1330 1167257 NP_698566.1 CDS BR1575 NC_004310.3 1525554 1526750 R identified by similarity to OMNI:NTL02ML2131; hypothetical protein complement(1525554..1526750) Brucella suis 1330 1167258 NP_698567.1 CDS BR1576 NC_004310.3 1526747 1526896 R hypothetical protein complement(1526747..1526896) Brucella suis 1330 1167259 NP_698568.1 CDS BR1577 NC_004310.3 1526880 1527005 R hypothetical protein complement(1526880..1527005) Brucella suis 1330 1167260 NP_698569.1 CDS BR1578 NC_004310.3 1526982 1527101 D hypothetical protein 1526982..1527101 Brucella suis 1330 1167261 NP_698570.1 CDS BR1579 NC_004310.3 1527186 1528154 D identified by similarity to GP:19880073; match to protein family HMM PF04069; glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein 1527186..1528154 Brucella suis 1330 1167262 NP_698571.1 CDS BR1580 NC_004310.3 1528243 1529079 D identified by similarity to GP:17982347; match to protein family HMM PF00528; glycine betaine/L-proline ABC transporter permease 1528243..1529079 Brucella suis 1330 1167263 NP_698572.1 CDS BR1581 NC_004310.3 1529249 1530295 D identified by similarity to SP:P46920; match to protein family HMM PF00005; glycine betaine/L-proline ABC transporter ATP-binding protein 1529249..1530295 Brucella suis 1330 1167264 NP_698573.1 CDS BR1582 NC_004310.3 1530569 1531417 R identified by similarity to SP:P37313; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein complement(1530569..1531417) Brucella suis 1330 1167265 NP_698574.1 CDS BR1583 NC_004310.3 1531414 1532262 R identified by similarity to SP:P37314; match to protein family HMM PF00005; dipeptide ABC transporter ATP-binding protein complement(1531414..1532262) Brucella suis 1330 1167266 NP_698575.1 CDS BR1584 NC_004310.3 1532268 1533149 R identified by similarity to SP:P94312; match to protein family HMM PF00528; dipeptide ABC transporter permease complement(1532268..1533149) Brucella suis 1330 1167267 NP_698576.1 CDS BR1585 NC_004310.3 1533157 1534164 R identified by similarity to SP:P94311; match to protein family HMM PF00528; dipeptide ABC transporter permease complement(1533157..1534164) Brucella suis 1330 1167268 NP_698577.1 CDS BR1587 NC_004310.3 1536202 1536507 D hypothetical protein 1536202..1536507 Brucella suis 1330 1167270 NP_698578.1 CDS BR1588 NC_004310.3 1536748 1536975 R hypothetical protein complement(1536748..1536975) Brucella suis 1330 1167271 NP_698579.1 CDS BR1589 NC_004310.3 1536965 1537312 D identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1536965..1537312 Brucella suis 1330 1167272 NP_698580.1 CDS BR1590 NC_004310.3 1537342 1538172 D identified by match to protein family HMM PF00588; RNA methyltransferase 1537342..1538172 Brucella suis 1330 1167273 NP_698581.1 CDS mnmA NC_004310.3 1538394 1539590 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(1538394..1539590) Brucella suis 1330 1167274 NP_698582.1 CDS BR1592 NC_004310.3 1539628 1539786 R hypothetical protein complement(1539628..1539786) Brucella suis 1330 1167275 NP_698583.1 CDS BR1593 NC_004310.3 1539895 1540170 D identified by similarity to GP:15075739; hypothetical protein 1539895..1540170 Brucella suis 1330 1167276 NP_698584.1 CDS BR1594 NC_004310.3 1540373 1540666 D identified by similarity to GP:15075740; hypothetical protein 1540373..1540666 Brucella suis 1330 1167277 NP_698585.1 CDS BR1595 NC_004310.3 1540714 1541649 R identified by similarity to GP:14023239; hypothetical protein complement(1540714..1541649) Brucella suis 1330 1167278 NP_698586.1 CDS BR1596 NC_004310.3 1541879 1542475 R identified by similarity to GP:17740928; hypothetical protein complement(1541879..1542475) Brucella suis 1330 1167279 NP_698587.1 CDS BR1597 NC_004310.3 1542745 1542888 R hypothetical protein complement(1542745..1542888) Brucella suis 1330 1167280 NP_698588.1 CDS BR1598 NC_004310.3 1542887 1543516 D identified by similarity to OMNI:NTL02ML2168; hypothetical protein 1542887..1543516 Brucella suis 1330 1167281 NP_698589.1 CDS ctrA NC_004310.3 1543629 1544327 R identified by similarity to EGAD:41053; match to protein family HMM PF00072; match to protein family HMM PF00486; cell cycle transcriptional regulator CtrA complement(1543629..1544327) Brucella suis 1330 1167282 NP_698590.1 CDS BR1600 NC_004310.3 1544858 1545250 D identified by similarity to GP:15075741; hypothetical protein 1544858..1545250 Brucella suis 1330 1167283 NP_698591.1 CDS BR1601 NC_004310.3 1545334 1546458 R identified by match to protein family HMM PF01041; DegT/DnrJ/EryC1/StrS family protein complement(1545334..1546458) Brucella suis 1330 1167284 NP_698592.1 CDS BR1602 NC_004310.3 1546618 1547574 R identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase complement(1546618..1547574) Brucella suis 1330 1167285 NP_698593.1 CDS BR1603 NC_004310.3 1547580 1547705 R hypothetical protein complement(1547580..1547705) Brucella suis 1330 1167286 NP_698594.1 CDS BR1604 NC_004310.3 1547976 1548230 D hypothetical protein 1547976..1548230 Brucella suis 1330 1167288 NP_698595.1 CDS BR1605 NC_004310.3 1548406 1549188 R identified by match to protein family HMM PF01755; glycosyl transferase complement(1548406..1549188) Brucella suis 1330 1167289 NP_698596.1 CDS BR1606 NC_004310.3 1549933 1553040 D identified by match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229; sensory box histidine kinase 1549933..1553040 Brucella suis 1330 1167291 NP_698597.1 CDS BR1607 NC_004310.3 1553260 1553391 R hypothetical protein complement(1553260..1553391) Brucella suis 1330 1167292 NP_698598.1 CDS BR1608 NC_004310.3 1553781 1555718 D identified by similarity to EGAD:20142; match to protein family HMM PF05170; AsmA family protein 1553781..1555718 Brucella suis 1330 1167293 NP_698599.1 CDS BR1609 NC_004310.3 1555726 1556547 R identified by similarity to GP:16502083; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease complement(1555726..1556547) Brucella suis 1330 1167294 NP_698600.1 CDS BR1610 NC_004310.3 1556549 1557460 R identified by similarity to SP:P23860; match to protein family HMM PF00528; spermidine/putrescine ABC transporter permease complement(1556549..1557460) Brucella suis 1330 1167295 NP_698601.1 CDS BR1611 NC_004310.3 1557476 1558621 R identified by similarity to SP:P31134; match to protein family HMM PF00005; match to protein family HMM TIGR01187; spermidine/putrescine ABC transporter ATP-binding protein complement(1557476..1558621) Brucella suis 1330 1167296 NP_698602.1 CDS BR1612 NC_004310.3 1558863 1559966 R identified by similarity to GP:15979381; match to protein family HMM PF01547; spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein complement(1558863..1559966) Brucella suis 1330 1167297 NP_698603.1 CDS BR1613 NC_004310.3 1560188 1561600 R identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator complement(1560188..1561600) Brucella suis 1330 1167298 NP_698604.1 CDS aceA NC_004310.3 1561849 1563138 D Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates; isocitrate lyase 1561849..1563138 Brucella suis 1330 1167299 NP_698605.1 CDS BR1615 NC_004310.3 1563173 1563409 D identified by similarity to OMNI:NTL02ML5126; hypothetical protein 1563173..1563409 Brucella suis 1330 1167300 NP_698606.1 CDS BR1616 NC_004310.3 1563406 1563534 D hypothetical protein 1563406..1563534 Brucella suis 1330 1167301 NP_698607.1 CDS BR1617 NC_004310.3 1563518 1563673 R hypothetical protein complement(1563518..1563673) Brucella suis 1330 1167302 NP_698608.1 CDS BR1618 NC_004310.3 1564371 1565138 D Acts on the hydroxyl group at position 7 of the steroid frame; 7-alpha-hydroxysteroid dehydrogenase 1564371..1565138 Brucella suis 1330 1167304 NP_698609.1 CDS BR1619 NC_004310.3 1565204 1565998 D identified by similarity to EGAD:23950; match to protein family HMM PF00106; 7-alpha-hydroxysteroid dehydrogenase 1565204..1565998 Brucella suis 1330 1167305 NP_698610.1 CDS BR1620 NC_004310.3 1566008 1567765 D hypothetical protein 1566008..1567765 Brucella suis 1330 1167306 NP_698611.1 CDS BR1621 NC_004310.3 1567793 1568395 D identified by similarity to EGAD:10584; match to protein family HMM PF01914; hypothetical protein 1567793..1568395 Brucella suis 1330 1167307 NP_698612.1 CDS omp31-1 NC_004310.3 1568674 1569459 D identified by similarity to EGAD:150060; match to protein family HMM PF01389; hypothetical protein 1568674..1569459 Brucella suis 1330 1167308 NP_698613.1 CDS BR1623 NC_004310.3 1569596 1571146 R hypothetical protein complement(1569596..1571146) Brucella suis 1330 1167309 NP_698615.1 CDS BR1625 NC_004310.3 1571447 1571548 R hypothetical protein complement(1571447..1571548) Brucella suis 1330 1167311 NP_698616.1 CDS BR1626 NC_004310.3 1571699 1571980 D hypothetical protein 1571699..1571980 Brucella suis 1330 1167312 NP_698617.1 CDS BR1629 NC_004310.3 1576891 1577664 R identified by match to protein family HMM PF00106; short chain dehydrogenase complement(1576891..1577664) Brucella suis 1330 1167315 NP_698618.1 CDS BR1630 NC_004310.3 1577753 1578742 R identified by similarity to OMNI:NTL02ML0801; match to protein family HMM PF00532; LacI family sugar-binding transcriptional regulator complement(1577753..1578742) Brucella suis 1330 1167316 NP_698619.1 CDS rbsC-2 NC_004310.3 1578918 1579922 R identified by similarity to SP:P04984; match to protein family HMM PF02653; ribose ABC transporter permease complement(1578918..1579922) Brucella suis 1330 1167317 NP_698620.1 CDS rbsA-2 NC_004310.3 1580018 1581478 R identified by similarity to SP:P04983; match to protein family HMM PF00005; ribose ABC transporter ATP-binding protein complement(1580018..1581478) Brucella suis 1330 1167318 NP_698621.1 CDS BR1633 NC_004310.3 1581658 1581795 D hypothetical protein 1581658..1581795 Brucella suis 1330 1167319 NP_698622.1 CDS BR1634 NC_004310.3 1581792 1582109 D hypothetical protein 1581792..1582109 Brucella suis 1330 1167320 NP_698623.1 CDS BR1635 NC_004310.3 1582239 1582367 R hypothetical protein complement(1582239..1582367) Brucella suis 1330 1167321 NP_698624.1 CDS BR1637 NC_004310.3 1584775 1584927 D hypothetical protein 1584775..1584927 Brucella suis 1330 1167325 NP_698625.1 CDS BR1638 NC_004310.3 1587882 1588124 D hypothetical protein 1587882..1588124 Brucella suis 1330 1167327 NP_698626.1 CDS BR1639 NC_004310.3 1590825 1591646 R identified by match to protein family HMM PF01614; IclR family transcriptional regulator complement(1590825..1591646) Brucella suis 1330 1167331 NP_698627.1 CDS gabD NC_004310.3 1591764 1593215 D identified by similarity to EGAD:16804; match to protein family HMM PF00171; match to protein family HMM TIGR01780; succinate-semialdehyde dehydrogenase 1591764..1593215 Brucella suis 1330 1167332 NP_698628.1 CDS BR1641 NC_004310.3 1593332 1593922 D hypothetical protein 1593332..1593922 Brucella suis 1330 1167333 NP_698629.1 CDS BR1642 NC_004310.3 1594035 1594553 D disulfide bond formation protein B 1594035..1594553 Brucella suis 1330 1167334 NP_698630.1 CDS BR1643 NC_004310.3 1594570 1595142 R identified by match to protein family HMM PF01844; HNH endonuclease complement(1594570..1595142) Brucella suis 1330 1167335 NP_698631.1 CDS BR1644 NC_004310.3 1595139 1595231 R hypothetical protein complement(1595139..1595231) Brucella suis 1330 1167336 NP_698632.1 CDS BR1645 NC_004310.3 1595293 1595400 R hypothetical protein complement(1595293..1595400) Brucella suis 1330 1167337 NP_698633.1 CDS BR1646 NC_004310.3 1595416 1596114 R identified by match to protein family HMM PF00730; base-excision DNA repair protein complement(1595416..1596114) Brucella suis 1330 1167338 NP_698634.1 CDS BR1647 NC_004310.3 1596136 1597011 D this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu; glutamyl-Q tRNA(Asp) synthetase 1596136..1597011 Brucella suis 1330 1167339 NP_698635.1 CDS glcB NC_004310.3 1597154 1599340 D catalyzes the formation of malate from glyoxylate and acetyl-CoA; malate synthase G 1597154..1599340 Brucella suis 1330 1167340 NP_698636.1 CDS BR1649 NC_004310.3 1599645 1600139 D identified by match to protein family HMM PF00583; acetyltransferase 1599645..1600139 Brucella suis 1330 1167341 NP_698637.1 CDS BR1650 NC_004310.3 1600198 1601109 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 complement(1600198..1601109) Brucella suis 1330 1167342 YP_089634.1 CDS BR1651 NC_004310.3 1601540 1602583 R identified by match to protein family HMM PF00849; match to protein family HMM PF01479; match to protein family HMM TIGR00005; ribosomal large subunit pseudouridine synthase D complement(1601540..1602583) Brucella suis 1330 1167343 NP_698638.1 CDS BR1652 NC_004310.3 1602600 1603076 D hypothetical protein 1602600..1603076 Brucella suis 1330 1167344 NP_698639.1 CDS BR1653 NC_004310.3 1603110 1603283 D hypothetical protein 1603110..1603283 Brucella suis 1330 1167345 NP_698640.1 CDS BR1654 NC_004310.3 1603455 1603880 D identified by similarity to SP:O30976; match to protein family HMM PF01475; ferric uptake regulation protein 1603455..1603880 Brucella suis 1330 1167347 NP_698641.1 CDS BR1655 NC_004310.3 1604116 1605051 R sensor histidine kinase complement(1604116..1605051) Brucella suis 1330 1167348 NP_698642.1 CDS BR1656 NC_004310.3 1605319 1605528 R hypothetical protein complement(1605319..1605528) Brucella suis 1330 1167349 NP_698643.1 CDS BR1657 NC_004310.3 1605633 1606427 R in Caulobacter crescentus, CC3477 is differentially expressed in minimal salts media with glucose as compared to complex media; two-component response regulator complement(1605633..1606427) Brucella suis 1330 1167350 NP_698644.1 CDS BR1658 NC_004310.3 1606874 1607446 D Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor 1606874..1607446 Brucella suis 1330 1167351 NP_698645.1 CDS BR1659 NC_004310.3 1607647 1609077 D identified by match to protein family HMM PF02518; match to protein family HMM PF05227; sensor histidine kinase 1607647..1609077 Brucella suis 1330 1167352 NP_698646.1 CDS BR1660 NC_004310.3 1609138 1609569 R hypothetical protein complement(1609138..1609569) Brucella suis 1330 1167353 NP_698647.1 CDS BR1661 NC_004310.3 1609578 1609931 R identified by similarity to OMNI:NTL02ML2854; hypothetical protein complement(1609578..1609931) Brucella suis 1330 1167354 NP_698648.1 CDS BR1662 NC_004310.3 1610096 1610938 R identified by similarity to OMNI:NTL02ML2849; match to protein family HMM PF05239; hypothetical protein complement(1610096..1610938) Brucella suis 1330 1167355 NP_698649.1 CDS BR1663 NC_004310.3 1610958 1611071 R hypothetical protein complement(1610958..1611071) Brucella suis 1330 1167356 NP_698650.1 CDS BR1664 NC_004310.3 1611111 1611269 R hypothetical protein complement(1611111..1611269) Brucella suis 1330 1167357 NP_698651.1 CDS BR1665 NC_004310.3 1611400 1611603 D hypothetical protein 1611400..1611603 Brucella suis 1330 1167358 NP_698652.1 CDS exbB NC_004310.3 1611765 1612643 D identified by similarity to SP:P18783; match to protein family HMM PF01618; biopolymer transport protein ExbB 1611765..1612643 Brucella suis 1330 1167359 NP_698653.1 CDS BR1667 NC_004310.3 1612649 1613143 D identified by similarity to SP:Q05606; match to protein family HMM PF02472; TonB system transport protein ExbD 1612649..1613143 Brucella suis 1330 1167360 NP_698654.1 CDS BR1668 NC_004310.3 1613140 1614066 D identified by match to protein family HMM TIGR01352; TonB-dependent receptor 1613140..1614066 Brucella suis 1330 1167361 NP_698655.1 CDS BR1669 NC_004310.3 1614109 1614879 R identified by similarity to GP:15074996; hypothetical protein complement(1614109..1614879) Brucella suis 1330 1167362 NP_698656.1 CDS BR1671 NC_004310.3 1616853 1618079 R identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730; HlyD family secretion protein complement(1616853..1618079) Brucella suis 1330 1167364 NP_698657.1 CDS BR1672 NC_004310.3 1618176 1618487 D identified by similarity to EGAD:46813; IS711, transposase orfA 1618176..1618487 Brucella suis 1330 1167365 NP_698658.1 CDS BR1673 NC_004310.3 1618519 1618911 D identified by similarity to PIR:PN0685; match to protein family HMM PF01609; IS711, transposase orfB 1618519..1618911 Brucella suis 1330 1167366 NP_698659.1 CDS BR1674 NC_004310.3 1618925 1619050 R hypothetical protein complement(1618925..1619050) Brucella suis 1330 1167367 NP_698660.1 CDS dut NC_004310.3 1619158 1619631 R catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase complement(1619158..1619631) Brucella suis 1330 1167368 NP_698661.1 CDS BR1676 NC_004310.3 1619855 1620325 R identified by match to protein family HMM PF01037; match to protein family HMM TIGR01199; AsnC family transcriptional regulator complement(1619855..1620325) Brucella suis 1330 1167369 NP_698662.1 CDS BR1677 NC_004310.3 1620471 1620686 D identified by similarity to OMNI:NTL02ML4136; hypothetical protein 1620471..1620686 Brucella suis 1330 1167370 NP_698663.1 CDS BR1678 NC_004310.3 1620726 1621589 D identified by similarity to GP:13932326; match to protein family HMM PF00310; glutamine amidotransferase 1620726..1621589 Brucella suis 1330 1167371 NP_698664.1 CDS BR1679 NC_004310.3 1621616 1622599 R identified by match to protein family HMM PF01988; hypothetical protein complement(1621616..1622599) Brucella suis 1330 1167372 NP_698665.1 CDS BR1680 NC_004310.3 1622716 1624146 D identified by match to protein family HMM PF00083; major facilitator family transporter 1622716..1624146 Brucella suis 1330 1167373 NP_698666.1 CDS BR1681 NC_004310.3 1624356 1625753 R identified by similarity to OMNI:NTL02ML2989; hypothetical protein complement(1624356..1625753) Brucella suis 1330 1167374 NP_698667.1 CDS BR1682 NC_004310.3 1625951 1626061 R hypothetical protein complement(1625951..1626061) Brucella suis 1330 1167375 NP_698668.1 CDS purA NC_004310.3 1626066 1627355 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(1626066..1627355) Brucella suis 1330 1167376 NP_698669.1 CDS BR1684 NC_004310.3 1627673 1628182 R identified by match to protein family HMM PF00583; acetyltransferase complement(1627673..1628182) Brucella suis 1330 1167377 NP_698670.1 CDS serA-1 NC_004310.3 1628187 1629788 R catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase complement(1628187..1629788) Brucella suis 1330 1167378 NP_698671.1 CDS BR1686 NC_004310.3 1629760 1629930 R hypothetical protein complement(1629760..1629930) Brucella suis 1330 1167379 NP_698672.1 CDS serC NC_004310.3 1629942 1631117 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; phosphoserine aminotransferase complement(1629942..1631117) Brucella suis 1330 1167380 NP_698673.1 CDS BR1688 NC_004310.3 1631268 1632224 R identified by match to protein family HMM PF01758; sodium/bile acid transporter family protein complement(1631268..1632224) Brucella suis 1330 1167381 NP_698674.1 CDS BR1689 NC_004310.3 1632405 1633229 R identified by similarity to GP:17742129; outer surface protein complement(1632405..1633229) Brucella suis 1330 1167382 NP_698675.1 CDS glmM NC_004310.3 1633414 1634769 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1633414..1634769) Brucella suis 1330 1167383 NP_698676.1 CDS ftsH NC_004310.3 1635074 1637008 R identified by similarity to EGAD:13183; match to protein family HMM PF00004; match to protein family HMM PF01434; match to protein family HMM TIGR01241; cell division protein FtsH complement(1635074..1637008) Brucella suis 1330 1167384 NP_698677.1 CDS BR1692 NC_004310.3 1637144 1638490 R identified by similarity to GP:15075760; match to protein family HMM PF01171; hypothetical protein complement(1637144..1638490) Brucella suis 1330 1167385 NP_698678.1 CDS BR1693 NC_004310.3 1638506 1639972 R hypothetical protein complement(1638506..1639972) Brucella suis 1330 1167386 NP_698679.1 CDS BR1694 NC_004310.3 1640089 1640205 R hypothetical protein complement(1640089..1640205) Brucella suis 1330 1167387 NP_698680.1 CDS BR1695 NC_004310.3 1640369 1640875 R identified by similarity to EGAD:9123; match to protein family HMM PF00691; Pal family lipoprotein complement(1640369..1640875) Brucella suis 1330 1167388 NP_698681.1 CDS BR1696 NC_004310.3 1640924 1641103 R hypothetical protein complement(1640924..1641103) Brucella suis 1330 1167389 NP_698682.1 CDS tolB NC_004310.3 1641163 1642494 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(1641163..1642494) Brucella suis 1330 1167390 NP_698683.1 CDS tolA NC_004310.3 1642550 1643620 R identified by similarity to GP:13898975; tolA protein complement(1642550..1643620) Brucella suis 1330 1167391 NP_698684.1 CDS BR1699 NC_004310.3 1643628 1644080 R identified by match to protein family HMM PF02472; ExbD/TolR family TonB system transport protein complement(1643628..1644080) Brucella suis 1330 1167392 NP_698685.1 CDS tolQ NC_004310.3 1644127 1644837 R identified by match to protein family HMM PF01618; tolQ protein complement(1644127..1644837) Brucella suis 1330 1167393 NP_698686.1 CDS BR1701 NC_004310.3 1645212 1645493 R hypothetical protein complement(1645212..1645493) Brucella suis 1330 1167394 NP_698687.1 CDS ruvB NC_004310.3 1645641 1646681 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(1645641..1646681) Brucella suis 1330 1167395 NP_698688.1 CDS ruvA NC_004310.3 1646722 1647339 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(1646722..1647339) Brucella suis 1330 1167396 NP_698689.1 CDS ruvC NC_004310.3 1647344 1647865 R endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity; Holliday junction resolvase complement(1647344..1647865) Brucella suis 1330 1167397 NP_698690.1 CDS BR1705 NC_004310.3 1647967 1648473 R identified by similarity to OMNI:NTL02ML3016; hypothetical protein complement(1647967..1648473) Brucella suis 1330 1167398 NP_698691.1 CDS BR1706 NC_004310.3 1648960 1650141 R identified by similarity to GP:9961345; opgC protein complement(1648960..1650141) Brucella suis 1330 1167399 NP_698692.1 CDS BR1707 NC_004310.3 1650386 1651051 D catalyzes the formation of thiamine monophosphate from 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate and 4-methyl-5-(2-phosphono-oxyethyl)-thiazole; thiamine-phosphate pyrophosphorylase 1650386..1651051 Brucella suis 1330 1167400 NP_698693.1 CDS BR1708 NC_004310.3 1651052 1652140 D identified by similarity to GP:14024100; hypothetical protein 1651052..1652140 Brucella suis 1330 1167401 NP_698694.1 CDS BR1709 NC_004310.3 1652149 1652256 D hypothetical protein 1652149..1652256 Brucella suis 1330 1167402 NP_698695.1 CDS efp NC_004310.3 1652405 1652965 D Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 1652405..1652965 Brucella suis 1330 1167403 NP_698696.1 CDS BR1711 NC_004310.3 1653151 1653942 D identified by similarity to EGAD:15335; match to protein family HMM PF00459; inositol monophosphatase 1653151..1653942 Brucella suis 1330 1167404 NP_698697.1 CDS BR1712 NC_004310.3 1653947 1654057 D hypothetical protein 1653947..1654057 Brucella suis 1330 1167405 NP_698698.1 CDS BR1713 NC_004310.3 1654197 1655246 D identified by similarity to GP:15075801; hypothetical protein 1654197..1655246 Brucella suis 1330 1167406 NP_698699.1 CDS BR1714 NC_004310.3 1655253 1656284 D identified by match to protein family HMM PF00691; hypothetical protein 1655253..1656284 Brucella suis 1330 1167407 NP_698700.1 CDS BR1715 NC_004310.3 1656318 1658117 R identified by match to protein family HMM PF00005; match to protein family HMM PF00664; ABC transporter ATP binding/permease complement(1656318..1658117) Brucella suis 1330 1167408 NP_698701.1 CDS rpmE NC_004310.3 1658433 1658654 D RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 1658433..1658654 Brucella suis 1330 1167409 NP_698702.1 CDS BR1717 NC_004310.3 1658882 1659628 R identified by similarity to GP:15075777; match to protein family HMM PF01709; match to protein family HMM TIGR01033; hypothetical protein complement(1658882..1659628) Brucella suis 1330 1167410 NP_698703.1 CDS BR1719 NC_004310.3 1660704 1661279 D identified by match to protein family HMM PF02632; BioY family protein 1660704..1661279 Brucella suis 1330 1167412 NP_698704.1 CDS BR1720 NC_004310.3 1661290 1661718 D identified by similarity to GP:14026938; hypothetical protein 1661290..1661718 Brucella suis 1330 1167413 NP_698705.1 CDS BR1721 NC_004310.3 1661731 1662474 R identified by similarity to OMNI:NTL02ML3047; match to protein family HMM PF03741; hypothetical protein complement(1661731..1662474) Brucella suis 1330 1167414 NP_698706.1 CDS BR1722 NC_004310.3 1662685 1663509 R identified by similarity to OMNI:NTL02ML3048; match to protein family HMM PF00149; match to protein family HMM TIGR00282; hypothetical protein complement(1662685..1663509) Brucella suis 1330 1167415 NP_698707.1 CDS BR1723 NC_004310.3 1663618 1664214 R identified by match to protein family HMM PF01812; 5-formyltetrahydrofolate cyclo-ligase complement(1663618..1664214) Brucella suis 1330 1167416 NP_698708.1 CDS BR1724 NC_004310.3 1664602 1664967 R identified by similarity to OMNI:NTL02ML2891; match to protein family HMM PF05164; hypothetical protein complement(1664602..1664967) Brucella suis 1330 1167417 NP_698709.1 CDS BR1725 NC_004310.3 1664977 1665249 R hypothetical protein complement(1664977..1665249) Brucella suis 1330 1167418 NP_698710.1 CDS BR1726 NC_004310.3 1665392 1665487 R hypothetical protein complement(1665392..1665487) Brucella suis 1330 1167419 NP_698711.1 CDS tkt NC_004310.3 1665666 1667657 D catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 1665666..1667657 Brucella suis 1330 1167420 NP_698712.1 CDS gap NC_004310.3 1667798 1668805 D catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; glyceraldehyde-3-phosphate dehydrogenase 1667798..1668805 Brucella suis 1330 1167421 NP_698713.1 CDS pgk NC_004310.3 1668876 1670063 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1668876..1670063 Brucella suis 1330 1167422 NP_698714.1 CDS BR1730 NC_004310.3 1670354 1670518 R identified by similarity to GP:15075794; hypothetical protein complement(1670354..1670518) Brucella suis 1330 1167423 NP_698715.1 CDS prpE NC_004310.3 1670792 1672702 D identified by match to protein family HMM PF00501; propionate--CoA ligase 1670792..1672702 Brucella suis 1330 1167424 NP_698716.1 CDS BR1732 NC_004310.3 1672632 1672940 D identified by similarity to GP:7206791; hypothetical protein 1672632..1672940 Brucella suis 1330 1167425 NP_698717.1 CDS BR1733 NC_004310.3 1673047 1673271 D hypothetical protein 1673047..1673271 Brucella suis 1330 1167426 NP_698718.1 CDS BR1734 NC_004310.3 1673278 1673979 D transcriptional regulator 1673278..1673979 Brucella suis 1330 1167427 NP_698719.1 CDS BR1735 NC_004310.3 1674232 1674339 R hypothetical protein complement(1674232..1674339) Brucella suis 1330 1167428 NP_698720.1 CDS BR1736 NC_004310.3 1674382 1674789 D identified by similarity to OMNI:CC2103; match to protein family HMM PF03061; match to protein family HMM TIGR00369; hypothetical protein 1674382..1674789 Brucella suis 1330 1167429 NP_698721.1 CDS BR1737 NC_004310.3 1674868 1675557 R identified by similarity to GP:15076354; hypothetical protein complement(1674868..1675557) Brucella suis 1330 1167430 NP_698722.1 CDS BR1738 NC_004310.3 1675685 1676665 R identified by match to protein family HMM PF00107; alcohol dehydrogenase complement(1675685..1676665) Brucella suis 1330 1167431 NP_698723.1 CDS BR1739 NC_004310.3 1676882 1677073 D identified by similarity to GP:15075796; hypothetical protein 1676882..1677073 Brucella suis 1330 1167432 NP_698724.1 CDS BR1740 NC_004310.3 1677171 1678409 D transporter 1677171..1678409 Brucella suis 1330 1167433 NP_698725.1 CDS BR1741 NC_004310.3 1678552 1678731 R identified by match to protein family HMM PF04325; hypothetical protein complement(1678552..1678731) Brucella suis 1330 1167434 NP_698726.1 CDS BR1742 NC_004310.3 1678790 1679011 R hypothetical protein complement(1678790..1679011) Brucella suis 1330 1167435 NP_698727.1 CDS BR1743 NC_004310.3 1679125 1679328 D identified by similarity to OMNI:NTL02ML2929; match to protein family HMM PF04325; hypothetical protein 1679125..1679328 Brucella suis 1330 1167436 NP_698728.1 CDS purE NC_004310.3 1679426 1679914 D identified by similarity to SP:P09028; match to protein family HMM PF00731; match to protein family HMM TIGR01162; phosphoribosylaminoimidazole carboxylase, catalytic subunit 1679426..1679914 Brucella suis 1330 1167437 NP_698729.1 CDS purK NC_004310.3 1680006 1681019 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 1680006..1681019 Brucella suis 1330 1167438 NP_698730.1 CDS rpmJ NC_004310.3 1681255 1681380 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif; 50S ribosomal protein L36 1681255..1681380 Brucella suis 1330 1167439 NP_698731.1 CDS BR1747 NC_004310.3 1681418 1682107 D identified by match to protein family HMM PF00515; TPR domain-containing protein 1681418..1682107 Brucella suis 1330 1167440 NP_698732.1 CDS pyk NC_004310.3 1682359 1683795 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(1682359..1683795) Brucella suis 1330 1167441 NP_698733.1 CDS BR1749 NC_004310.3 1683792 1684253 R hypothetical protein complement(1683792..1684253) Brucella suis 1330 1167442 NP_698734.1 CDS BR1750 NC_004310.3 1684494 1685312 D identified by match to protein family HMM PF05013; hypothetical protein 1684494..1685312 Brucella suis 1330 1167443 NP_698735.1 CDS BR1751 NC_004310.3 1685309 1685470 D hypothetical protein 1685309..1685470 Brucella suis 1330 1167444 NP_698736.1 CDS BR1752 NC_004310.3 1685485 1685745 D hypothetical protein 1685485..1685745 Brucella suis 1330 1167445 NP_698737.1 CDS BR1753 NC_004310.3 1685837 1687654 R identified by similarity to GP:15157929; match to protein family HMM PF00005; ABC transporter ATP-binding protein complement(1685837..1687654) Brucella suis 1330 1167446 NP_698738.1 CDS BR1754 NC_004310.3 1687663 1687833 R hypothetical protein complement(1687663..1687833) Brucella suis 1330 1167447 NP_698739.1 CDS BR1755 NC_004310.3 1687802 1688086 R lipoprotein complement(1687802..1688086) Brucella suis 1330 1167448 NP_698740.1 CDS BR1756 NC_004310.3 1688220 1688876 R identified by similarity to OMNI:NTL02ML2986; match to protein family HMM PF04263; hypothetical protein complement(1688220..1688876) Brucella suis 1330 1167449 NP_698741.1 CDS tbpA NC_004310.3 1689183 1690187 D part of the thiamine and TPP transport system tbpA-thiPQ; thiamine transporter substrate binding subunit 1689183..1690187 Brucella suis 1330 1167450 NP_698742.1 CDS thiP NC_004310.3 1690184 1691815 D permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine; thiamine transporter membrane protein 1690184..1691815 Brucella suis 1330 1167451 NP_698743.1 CDS BR1759 NC_004310.3 1691812 1692537 D identified by match to protein family HMM PF00005; match to protein family HMM TIGR01277; thiamine ABC transporter ATP-binding protein 1691812..1692537 Brucella suis 1330 1167452 NP_698744.1 CDS BR1760 NC_004310.3 1692534 1692629 R hypothetical protein complement(1692534..1692629) Brucella suis 1330 1167453 NP_698745.1 CDS BR1761 NC_004310.3 1692804 1694285 D identified by match to protein family HMM PF01435; peptidase 1692804..1694285 Brucella suis 1330 1167454 NP_698746.1 CDS BR1762 NC_004310.3 1694312 1695040 D identified by similarity to OMNI:NTL03PA02229; match to protein family HMM PF03473; MOSC domain-containing protein 1694312..1695040 Brucella suis 1330 1167455 NP_698747.1 CDS rpoH2 NC_004310.3 1695128 1696063 R binds with the catalytic core of RNA polymerase to produce the holoenzyme; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma-32 is responsible for the expression of heat shock promoters; there are paralogs in Rhizobium and Sinorhizobium; the proteins in this cluster act as secondary heat shock sigma factors; the Rhizobium sigma-32 factor may also be involved in exopolysaccharide production; RNA polymerase factor sigma-32 complement(1695128..1696063) Brucella suis 1330 1167456 NP_698748.1 CDS BR1764 NC_004310.3 1696104 1696307 D hypothetical protein 1696104..1696307 Brucella suis 1330 1167457 NP_698749.1 CDS BR1765 NC_004310.3 1696227 1696436 R hypothetical protein complement(1696227..1696436) Brucella suis 1330 1167458 NP_698750.1 CDS BR1766 NC_004310.3 1696408 1696983 R identified by similarity to OMNI:NTL02ML2976; match to protein family HMM PF02559; transcriptional regulator complement(1696408..1696983) Brucella suis 1330 1167459 NP_698751.1 CDS fdxA NC_004310.3 1697501 1697839 R identified by similarity to EGAD:22805; match to protein family HMM PF00037; ferredoxin A complement(1697501..1697839) Brucella suis 1330 1167460 NP_698752.1 CDS BR1768 NC_004310.3 1697972 1698205 R hypothetical protein complement(1697972..1698205) Brucella suis 1330 1167461 NP_698753.1 CDS BR1769 NC_004310.3 1698202 1698615 R identified by match to protein family HMM PF01479; S4 domain-containing protein complement(1698202..1698615) Brucella suis 1330 1167462 NP_698754.1 CDS BR1771 NC_004310.3 1702095 1702415 R hypothetical protein complement(1702095..1702415) Brucella suis 1330 1167464 NP_698755.1 CDS phbA-1 NC_004310.3 1702399 1703583 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis; acetyl-CoA acetyltransferase complement(1702399..1703583) Brucella suis 1330 1167465 NP_698756.1 CDS BR1773 NC_004310.3 1703564 1703728 D hypothetical protein 1703564..1703728 Brucella suis 1330 1167466 NP_698757.1 CDS BR1774 NC_004310.3 1703759 1704190 D identified by similarity to OMNI:NTL02ML2916; match to protein family HMM PF03928; hypothetical protein 1703759..1704190 Brucella suis 1330 1167467 NP_698758.1 CDS rpmF NC_004310.3 1704322 1704501 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(1704322..1704501) Brucella suis 1330 1167468 NP_698759.1 CDS mtgA NC_004310.3 1704662 1705396 R glycosyltransferase; polymerizes glycan strands in the peptidoglycan; monofunctional biosynthetic peptidoglycan transglycosylase complement(1704662..1705396) Brucella suis 1330 1167469 NP_698760.1 CDS ispA NC_004310.3 1705583 1706497 D identified by similarity to SP:Q08291; match to protein family HMM PF00348; geranyltranstransferase 1705583..1706497 Brucella suis 1330 1167470 NP_698761.1 CDS ispG NC_004310.3 1706505 1707767 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(1706505..1707767) Brucella suis 1330 1167471 NP_698762.1 CDS BR1779 NC_004310.3 1707935 1708726 D identified by similarity to SP:O86034; match to protein family HMM PF00106; match to protein family HMM TIGR01963; D-beta-hydroxybutyrate dehydrogenase 1707935..1708726 Brucella suis 1330 1167472 NP_698763.1 CDS pyc NC_004310.3 1710000 1713476 R biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase complement(1710000..1713476) Brucella suis 1330 1167474 NP_698764.1 CDS BR1782 NC_004310.3 1713742 1714857 R identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein complement(1713742..1714857) Brucella suis 1330 1167475 NP_698765.1 CDS BR1783 NC_004310.3 1715000 1715131 R hypothetical protein complement(1715000..1715131) Brucella suis 1330 1167476 NP_698766.1 CDS BR1784 NC_004310.3 1715135 1715287 D hypothetical protein 1715135..1715287 Brucella suis 1330 1167477 NP_698767.1 CDS BR1785 NC_004310.3 1715478 1716593 R identified by similarity to SP:P04816; match to protein family HMM PF01094; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein complement(1715478..1716593) Brucella suis 1330 1167478 NP_698768.1 CDS BR1786 NC_004310.3 1716612 1716743 D hypothetical protein 1716612..1716743 Brucella suis 1330 1167479 NP_698769.1 CDS BR1787 NC_004310.3 1716745 1717089 R identified by similarity to OMNI:NTL02ML3062; hypothetical protein complement(1716745..1717089) Brucella suis 1330 1167480 NP_698770.1 CDS BR1789 NC_004310.3 1717843 1719165 R identified by match to protein family HMM PF00005; branched-chain amino acid ABC transporter ATP-binding protein complement(1717843..1719165) Brucella suis 1330 1167482 NP_698771.1 CDS BR1790 NC_004310.3 1719183 1720562 R identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease complement(1719183..1720562) Brucella suis 1330 1167483 NP_698772.1 CDS BR1791 NC_004310.3 1720565 1721473 R identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease complement(1720565..1721473) Brucella suis 1330 1167484 NP_698773.1 CDS BR1792 NC_004310.3 1721767 1722768 R identified by similarity to GP:9695312; match to protein family HMM PF05544; hydroxyproline-2-epimerase complement(1721767..1722768) Brucella suis 1330 1167485 NP_698774.1 CDS BR1794 NC_004310.3 1724059 1724259 D hypothetical protein 1724059..1724259 Brucella suis 1330 1167487 NP_698775.1 CDS BR1795 NC_004310.3 1724315 1725010 D identified by match to protein family HMM PF00392; GntR family transcriptional regulator 1724315..1725010 Brucella suis 1330 1167488 NP_698776.1 CDS BR1796 NC_004310.3 1725083 1725658 R identified by similarity to EGAD:16739; match to protein family HMM PF01047; MarR family transcriptional regulator complement(1725083..1725658) Brucella suis 1330 1167489 NP_698777.1 CDS BR1797 NC_004310.3 1725681 1725782 R hypothetical protein complement(1725681..1725782) Brucella suis 1330 1167490 NP_698778.1 CDS atpC NC_004310.3 1725863 1726270 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon complement(1725863..1726270) Brucella suis 1330 1167491 NP_698779.1 CDS atpD NC_004310.3 1726395 1727960 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta complement(1726395..1727960) Brucella suis 1330 1167492 NP_698780.1 CDS atpG NC_004310.3 1728088 1728966 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma complement(1728088..1728966) Brucella suis 1330 1167493 NP_698781.1 CDS atpA NC_004310.3 1728988 1730517 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha complement(1728988..1730517) Brucella suis 1330 1167494 NP_698782.1 CDS atpH NC_004310.3 1730517 1731077 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta complement(1730517..1731077) Brucella suis 1330 1167495 NP_698783.1 CDS BR1803 NC_004310.3 1731359 1731772 R identified by similarity to GP:15076063; hypothetical protein complement(1731359..1731772) Brucella suis 1330 1167496 NP_698784.1 CDS priA NC_004310.3 1731839 1734073 R binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosome assembly protein PriA complement(1731839..1734073) Brucella suis 1330 1167497 NP_698785.1 CDS BR1805 NC_004310.3 1734183 1734836 D similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 1734183..1734836 Brucella suis 1330 1167498 NP_698786.1 CDS BR1806 NC_004310.3 1734980 1735561 R identified by similarity to OMNI:NTL02ML3139; hypothetical protein complement(1734980..1735561) Brucella suis 1330 1167499 NP_698787.1 CDS leuS NC_004310.3 1735548 1738181 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase complement(1735548..1738181) Brucella suis 1330 1167500 NP_698788.1 CDS BR1808 NC_004310.3 1738304 1738984 D identified by similarity to OMNI:NTL02ML3141; match to protein family HMM PF01168; match to protein family HMM TIGR00044; hypothetical protein 1738304..1738984 Brucella suis 1330 1167501 NP_698789.1 CDS BR1809 NC_004310.3 1738997 1739527 R hypothetical protein complement(1738997..1739527) Brucella suis 1330 1167502 NP_698790.1 CDS BR1810 NC_004310.3 1739598 1739885 R identified by similarity to EGAD:13628; usg protein complement(1739598..1739885) Brucella suis 1330 1167503 NP_698791.1 CDS BR1811 NC_004310.3 1740226 1742181 D Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-CoA synthetase 1740226..1742181 Brucella suis 1330 1167504 NP_698792.1 CDS BR1812 NC_004310.3 1742337 1742564 R identified by similarity to GP:14024231; hypothetical protein complement(1742337..1742564) Brucella suis 1330 1167505 NP_698793.1 CDS htpX NC_004310.3 1742687 1743664 D metalloprotease; heat shock protein HtpX 1742687..1743664 Brucella suis 1330 1167506 NP_698794.1 CDS sun NC_004310.3 1743680 1745077 D identified by match to protein family HMM PF01029; match to protein family HMM PF01189; sun protein 1743680..1745077 Brucella suis 1330 1167507 NP_698795.1 CDS BR1815 NC_004310.3 1745309 1746940 D identified by similarity to GP:14024235; hypothetical protein 1745309..1746940 Brucella suis 1330 1167508 NP_698796.1 CDS purH NC_004310.3 1747047 1748663 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 1747047..1748663 Brucella suis 1330 1167509 NP_698797.1 CDS BR1817 NC_004310.3 1748713 1750080 R hypothetical protein complement(1748713..1750080) Brucella suis 1330 1167510 NP_698798.1 CDS BR1818 NC_004310.3 1750014 1750322 D hypothetical protein 1750014..1750322 Brucella suis 1330 1167511 NP_698799.1 CDS BR1819 NC_004310.3 1750300 1755102 R identified by similarity to GP:15076346; match to protein family HMM PF05088; match to protein family HMM TIGR01612; hypothetical protein complement(1750300..1755102) Brucella suis 1330 1167512 NP_698800.1 CDS BR1820 NC_004310.3 1755367 1756008 R identified by similarity to GP:14024253; hypothetical protein complement(1755367..1756008) Brucella suis 1330 1167513 NP_698801.1 CDS BR1821 NC_004310.3 1756021 1756824 R identified by similarity to GP:14024255; match to protein family HMM PF04536; hypothetical protein complement(1756021..1756824) Brucella suis 1330 1167514 NP_698802.1 CDS BR1822 NC_004310.3 1756905 1757528 R identified by similarity to EGAD:149857; match to protein family HMM PF04011; hypothetical protein complement(1756905..1757528) Brucella suis 1330 1167515 NP_698803.1 CDS BR1823 NC_004310.3 1757525 1757698 R hypothetical protein complement(1757525..1757698) Brucella suis 1330 1167516 NP_698804.1 CDS rpsP NC_004310.3 1757798 1758202 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(1757798..1758202) Brucella suis 1330 1167517 NP_698805.1 CDS BR1825 NC_004310.3 1758269 1758583 R catalyzes the interconversion of chorismate to prephenate; chorismate mutase complement(1758269..1758583) Brucella suis 1330 1167518 NP_698806.1 CDS ffh NC_004310.3 1758589 1760160 R identified by similarity to EGAD:6526; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM PF02978; match to protein family HMM TIGR00959; signal recognition particle protein complement(1758589..1760160) Brucella suis 1330 1167519 NP_698807.1 CDS BR1827 NC_004310.3 1760284 1760655 D hypothetical protein 1760284..1760655 Brucella suis 1330 1167520 NP_698808.1 CDS BR1828 NC_004310.3 1760595 1761422 D identified by similarity to OMNI:VC1956; lytic murein transglycosylase 1760595..1761422 Brucella suis 1330 1167521 NP_698809.1 CDS BR1829 NC_004310.3 1761486 1762127 R identified by match to protein family HMM PF00484; carbonic anhydrase complement(1761486..1762127) Brucella suis 1330 1167522 NP_698810.1 CDS BR1830 NC_004310.3 1762301 1763197 R catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal; pyridoxamine kinase complement(1762301..1763197) Brucella suis 1330 1167523 NP_698811.1 CDS BR1831 NC_004310.3 1763199 1763486 R identified by similarity to OMNI:NTL02ML3181; hypothetical protein complement(1763199..1763486) Brucella suis 1330 1167524 NP_698812.1 CDS mmsA NC_004310.3 1763859 1765355 R identified by similarity to SP:P28810; match to protein family HMM PF00171; match to protein family HMM TIGR01722; methylmalonic acid semialdehyde dehydrogenase complement(1763859..1765355) Brucella suis 1330 1167525 NP_698813.1 CDS BR1833 NC_004310.3 1765483 1766388 D identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator 1765483..1766388 Brucella suis 1330 1167526 NP_698814.1 CDS BR1834 NC_004310.3 1766599 1767243 R identified by similarity to OMNI:NTL03PA00256; hypothetical protein complement(1766599..1767243) Brucella suis 1330 1167527 NP_698815.1 CDS BR1835 NC_004310.3 1767237 1767629 D hypothetical protein 1767237..1767629 Brucella suis 1330 1167528 NP_698816.1 CDS BR1836 NC_004310.3 1767681 1768229 R hydrolyzes diadenosine polyphosphate; dinucleoside polyphosphate hydrolase complement(1767681..1768229) Brucella suis 1330 1167529 NP_698817.1 CDS BR1837 NC_004310.3 1768435 1769709 R identified by match to protein family HMM PF00595; match to protein family HMM PF03572; match to protein family HMM TIGR00225; carboxyl-terminal protease complement(1768435..1769709) Brucella suis 1330 1167530 NP_698818.1 CDS BR1838 NC_004310.3 1769753 1771102 R hypothetical protein complement(1769753..1771102) Brucella suis 1330 1167531 NP_698819.1 CDS BR1839 NC_004310.3 1771215 1772114 R hypothetical protein complement(1771215..1772114) Brucella suis 1330 1167532 NP_698820.1 CDS BR1840 NC_004310.3 1772232 1772756 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(1772232..1772756) Brucella suis 1330 1167533 NP_698821.1 CDS BR1841 NC_004310.3 1772775 1773128 R identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090; iojap-like protein complement(1772775..1773128) Brucella suis 1330 1167534 NP_698822.1 CDS nadD NC_004310.3 1773309 1773893 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1773309..1773893) Brucella suis 1330 1167535 NP_698823.1 CDS proA NC_004310.3 1773983 1775248 R Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase complement(1773983..1775248) Brucella suis 1330 1167536 NP_698824.1 CDS proB NC_004310.3 1775276 1776412 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase complement(1775276..1776412) Brucella suis 1330 1167537 NP_698825.1 CDS obgE NC_004310.3 1776440 1777465 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1776440..1777465) Brucella suis 1330 1167538 NP_698826.1 CDS BR1846 NC_004310.3 1777721 1778557 R hypothetical protein complement(1777721..1778557) Brucella suis 1330 1167539 NP_698827.1 CDS BR1847 NC_004310.3 1778966 1779523 R identified by match to protein family HMM PF00583; acetyltransferase complement(1778966..1779523) Brucella suis 1330 1167540 NP_698828.1 CDS BR1848 NC_004310.3 1779577 1780227 R identified by match to protein family HMM PF00583; acetyltransferase complement(1779577..1780227) Brucella suis 1330 1167541 NP_698829.1 CDS rpmA NC_004310.3 1780348 1780617 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1780348..1780617) Brucella suis 1330 1167542 NP_698830.1 CDS rplU NC_004310.3 1780643 1781071 R identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061; 50S ribosomal protein L21 complement(1780643..1781071) Brucella suis 1330 1167543 NP_698831.1 CDS BR1851 NC_004310.3 1781793 1782479 D transposase 1781793..1782479 Brucella suis 1330 1167545 NP_698832.1 CDS BR1852 NC_004310.3 1782720 1784648 D identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 1782720..1784648 Brucella suis 1330 1167546 NP_698833.1 CDS BR1853 NC_004310.3 1784645 1785319 D identified by match to protein family HMM PF03591; AzlC family protein 1784645..1785319 Brucella suis 1330 1167547 NP_698834.1 CDS BR1854 NC_004310.3 1785732 1785845 D hypothetical protein 1785732..1785845 Brucella suis 1330 1167548 NP_698835.1 CDS BR1855 NC_004310.3 1785878 1786564 R transposase complement(1785878..1786564) Brucella suis 1330 1167549 NP_698836.1 CDS BR1856 NC_004310.3 1786675 1788114 R identified by similarity to OMNI:CC1732; hypothetical protein complement(1786675..1788114) Brucella suis 1330 1167550 NP_698837.1 CDS BR1857 NC_004310.3 1788290 1788964 R hypothetical protein complement(1788290..1788964) Brucella suis 1330 1167551 NP_698838.1 CDS BR1858 NC_004310.3 1789282 1789449 D hypothetical protein 1789282..1789449 Brucella suis 1330 1167552 NP_698839.1 CDS BR1859 NC_004310.3 1789837 1789989 D hypothetical protein 1789837..1789989 Brucella suis 1330 1167555 NP_698840.1 CDS BR1860 NC_004310.3 1792944 1793186 D hypothetical protein 1792944..1793186 Brucella suis 1330 1167557 NP_698841.1 CDS BR1861 NC_004310.3 1796102 1798057 D identified by match to protein family HMM PF01551; M24/M37 family peptidase 1796102..1798057 Brucella suis 1330 1167561 NP_698842.1 CDS BR1862 NC_004310.3 1798125 1799351 R identified by similarity to GP:15075231; match to protein family HMM PF03734; hypothetical protein complement(1798125..1799351) Brucella suis 1330 1167562 NP_698843.1 CDS BR1863 NC_004310.3 1799400 1799525 D hypothetical protein 1799400..1799525 Brucella suis 1330 1167563 NP_698844.1 CDS clpB NC_004310.3 1800024 1802648 R identified by similarity to EGAD:20010; match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM TIGR01369; ATP-dependent Clp protease, ATP-binding subunit ClpB complement(1800024..1802648) Brucella suis 1330 1167564 NP_698845.1 CDS BR1865 NC_004310.3 1802847 1803605 R identified by similarity to GP:15159086; hypothetical protein complement(1802847..1803605) Brucella suis 1330 1167565 NP_698846.1 CDS BR1866 NC_004310.3 1803586 1803858 R hypothetical protein complement(1803586..1803858) Brucella suis 1330 1167566 NP_698847.1 CDS BR1867 NC_004310.3 1803920 1804066 D hypothetical protein 1803920..1804066 Brucella suis 1330 1167567 NP_698848.1 CDS BR1868 NC_004310.3 1804050 1804901 R identified by match to protein family HMM TIGR00536; hemK protein complement(1804050..1804901) Brucella suis 1330 1167568 NP_698849.1 CDS prfA NC_004310.3 1804934 1806013 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(1804934..1806013) Brucella suis 1330 1167569 NP_698850.1 CDS ptsP NC_004310.3 1806210 1808480 R identified by similarity to EGAD:36619; match to protein family HMM PF00391; match to protein family HMM PF01590; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417; phosphoenolpyruvate-protein phosphotransferase complement(1806210..1808480) Brucella suis 1330 1167570 NP_698851.1 CDS BR1871 NC_004310.3 1808808 1810079 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase complement(1808808..1810079) Brucella suis 1330 1167571 NP_698852.1 CDS ubiG NC_004310.3 1810297 1811043 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 1810297..1811043 Brucella suis 1330 1167572 NP_698853.1 CDS BR1873 NC_004310.3 1811049 1811930 R identified by match to protein family HMM PF00892; hypothetical protein complement(1811049..1811930) Brucella suis 1330 1167573 NP_698854.1 CDS BR1874 NC_004310.3 1811970 1812428 R identified by similarity to GP:15159831; hypothetical protein complement(1811970..1812428) Brucella suis 1330 1167574 NP_698855.1 CDS BR1875 NC_004310.3 1812401 1813255 R identified by match to protein family HMM PF00795; carbon-nitrogen hydrolase complement(1812401..1813255) Brucella suis 1330 1167575 NP_698856.1 CDS grxC NC_004310.3 1813266 1813532 R identified by similarity to SP:P37687; match to protein family HMM PF00462; glutaredoxin 3 complement(1813266..1813532) Brucella suis 1330 1167576 NP_698857.1 CDS BR1877 NC_004310.3 1813516 1813638 D hypothetical protein 1813516..1813638 Brucella suis 1330 1167577 NP_698858.1 CDS BR1878 NC_004310.3 1813616 1814404 R identified by similarity to EGAD:18112; competence protein F complement(1813616..1814404) Brucella suis 1330 1167578 NP_698859.1 CDS BR1879 NC_004310.3 1814587 1815480 D identified by similarity to GP:15075644; hypothetical protein 1814587..1815480 Brucella suis 1330 1167579 NP_698860.1 CDS BR1880 NC_004310.3 1815546 1815680 R hypothetical protein complement(1815546..1815680) Brucella suis 1330 1167580 NP_698861.1 CDS BR1882 NC_004310.3 1816884 1817363 R identified by similarity to GP:14024323; hypothetical protein complement(1816884..1817363) Brucella suis 1330 1167582 NP_698862.1 CDS BR1883 NC_004310.3 1817640 1817732 D hypothetical protein 1817640..1817732 Brucella suis 1330 1167583 NP_698863.1 CDS BR1884 NC_004310.3 1817779 1819350 R identified by similarity to GP:15076107; hypothetical protein complement(1817779..1819350) Brucella suis 1330 1167584 NP_698864.1 CDS BR1885 NC_004310.3 1819363 1820739 R identified by similarity to OMNI:NTL02ML3249; hypothetical protein complement(1819363..1820739) Brucella suis 1330 1167585 NP_698865.1 CDS hemD NC_004310.3 1820822 1821529 R catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; uroporphyrinogen-III synthase complement(1820822..1821529) Brucella suis 1330 1167586 NP_698866.1 CDS hemC NC_004310.3 1821553 1822497 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(1821553..1822497) Brucella suis 1330 1167587 NP_698867.1 CDS gcp NC_004310.3 1822616 1823695 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 1822616..1823695 Brucella suis 1330 1167588 NP_698868.1 CDS gpsA NC_004310.3 1823692 1824672 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 1823692..1824672 Brucella suis 1330 1167589 NP_698869.1 CDS BR1890 NC_004310.3 1824674 1824964 D unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity; hypothetical protein 1824674..1824964 Brucella suis 1330 1167590 NP_698870.1 CDS BR1891 NC_004310.3 1824977 1825405 D identified by similarity to GP:15157855; match to protein family HMM PF04543; hypothetical protein 1824977..1825405 Brucella suis 1330 1167591 NP_698871.1 CDS BR1892 NC_004310.3 1825405 1826061 D identified by similarity to GP:15076099; hypothetical protein 1825405..1826061 Brucella suis 1330 1167592 NP_698872.1 CDS BR1893 NC_004310.3 1826107 1826964 R identified by match to protein family HMM PF00892; hypothetical protein complement(1826107..1826964) Brucella suis 1330 1167593 NP_698873.1 CDS BR1895 NC_004310.3 1828634 1831198 R identified by similarity to EGAD:30442; match to protein family HMM PF01580; DNA translocase FtsK complement(1828634..1831198) Brucella suis 1330 1167595 NP_698874.1 CDS amt NC_004310.3 1831408 1832709 R identified by similarity to GP:3136068; match to protein family HMM PF00909; match to protein family HMM TIGR00836; ammonium transporter complement(1831408..1832709) Brucella suis 1330 1167596 NP_698875.1 CDS BR1897 NC_004310.3 1832683 1832841 D hypothetical protein 1832683..1832841 Brucella suis 1330 1167597 NP_698876.1 CDS tesB NC_004310.3 1832898 1833833 R identified by similarity to SP:P23911; match to protein family HMM PF02551; match to protein family HMM TIGR00189; acyl-CoA thioesterase complement(1832898..1833833) Brucella suis 1330 1167598 NP_698877.1 CDS BR1899 NC_004310.3 1834053 1835297 D identified by match to protein family HMM PF01360; 2-octaprenyl-6-methoxyphenyl hydroxylase 1834053..1835297 Brucella suis 1330 1167599 NP_698878.1 CDS BR1900 NC_004310.3 1835383 1835754 R identified by match to protein family HMM PF00903; glyoxalase complement(1835383..1835754) Brucella suis 1330 1167600 NP_698879.1 CDS sdhB NC_004310.3 1836001 1836780 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(1836001..1836780) Brucella suis 1330 1167601 NP_698880.1 CDS sdhA NC_004310.3 1836796 1838637 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(1836796..1838637) Brucella suis 1330 1167602 NP_698881.1 CDS BR1903 NC_004310.3 1838645 1839040 R identified by similarity to EGAD:23053; match to protein family HMM PF01127; succinate dehydrogenase, hydrophobic membrane anchor protein complement(1838645..1839040) Brucella suis 1330 1167603 NP_698882.1 CDS sdhC NC_004310.3 1839054 1839452 R identified by similarity to EGAD:15755; match to protein family HMM PF01127; succinate dehydrogenase, cytochrome b556 subunit complement(1839054..1839452) Brucella suis 1330 1167604 NP_698883.1 CDS BR1905 NC_004310.3 1839797 1840255 R identified by match to protein family HMM PF00583; acetyltransferase complement(1839797..1840255) Brucella suis 1330 1167605 NP_698884.1 CDS leuC NC_004310.3 1840512 1841921 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit complement(1840512..1841921) Brucella suis 1330 1167606 NP_698885.1 CDS rplS NC_004310.3 1842132 1842569 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1842132..1842569) Brucella suis 1330 1167607 NP_698886.1 CDS BR1908 NC_004310.3 1842861 1844324 D identified by match to protein family HMM PF02133; NCS1 nucleoside transporter family protein 1842861..1844324 Brucella suis 1330 1167608 NP_698887.1 CDS BR1910 NC_004310.3 1844725 1845135 R identified by similarity to GP:7739616; hypothetical protein complement(1844725..1845135) Brucella suis 1330 1167610 NP_698888.1 CDS BR1911 NC_004310.3 1845128 1845490 R identified by similarity to GP:15156392; match to protein family HMM PF03992; hypothetical protein complement(1845128..1845490) Brucella suis 1330 1167611 NP_698889.1 CDS BR1912 NC_004310.3 1845487 1845810 R identified by similarity to GP:15156391; hypothetical protein complement(1845487..1845810) Brucella suis 1330 1167612 NP_698890.1 CDS BR1913 NC_004310.3 1845881 1846546 D identified by match to protein family HMM PF01022; ArsR family transcriptional regulator 1845881..1846546 Brucella suis 1330 1167613 NP_698891.1 CDS trmD NC_004310.3 1846681 1847415 R methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase complement(1846681..1847415) Brucella suis 1330 1167614 NP_698892.1 CDS rimM NC_004310.3 1847412 1847981 R Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM complement(1847412..1847981) Brucella suis 1330 1167615 NP_698893.1 CDS xerC NC_004310.3 1848205 1849152 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerC 1848205..1849152 Brucella suis 1330 1167616 NP_698894.1 CDS BR1917 NC_004310.3 1849206 1850207 D identified by similarity to GP:15157831; hypothetical protein 1849206..1850207 Brucella suis 1330 1167617 NP_698895.1 CDS lpdA-2 NC_004310.3 1850411 1851814 R Catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase complement(1850411..1851814) Brucella suis 1330 1167618 NP_698896.1 CDS BR1919 NC_004310.3 1851983 1852525 R identified by similarity to GP:14024383; hypothetical protein complement(1851983..1852525) Brucella suis 1330 1167619 NP_698897.1 CDS BR1920 NC_004310.3 1852596 1853234 R identified by match to protein family HMM PF01810; amino acid transporter LysE complement(1852596..1853234) Brucella suis 1330 1167620 NP_698898.1 CDS BR1921 NC_004310.3 1853276 1853689 R identified by similarity to GP:15157838; match to protein family HMM PF01124; hypothetical protein complement(1853276..1853689) Brucella suis 1330 1167621 NP_698899.1 CDS sucB NC_004310.3 1853699 1854925 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoamide succinyltransferase complement(1853699..1854925) Brucella suis 1330 1167622 NP_698900.1 CDS sucA NC_004310.3 1854987 1858001 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 complement(1854987..1858001) Brucella suis 1330 1167623 NP_698901.1 CDS BR1924 NC_004310.3 1858138 1858287 D hypothetical protein 1858138..1858287 Brucella suis 1330 1167624 NP_698902.1 CDS sucD NC_004310.3 1858277 1859179 R Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA synthetase subunit alpha complement(1858277..1859179) Brucella suis 1330 1167625 NP_698903.1 CDS sucC NC_004310.3 1859183 1860379 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(1859183..1860379) Brucella suis 1330 1167626 NP_698904.1 CDS mdh NC_004310.3 1860486 1861448 R Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase complement(1860486..1861448) Brucella suis 1330 1167627 NP_698905.1 CDS BR1928 NC_004310.3 1861568 1861810 R hypothetical protein complement(1861568..1861810) Brucella suis 1330 1167628 NP_698906.1 CDS BR1929 NC_004310.3 1861887 1863050 R identified by similarity to GP:15076082; match to protein family HMM PF03969; hypothetical protein complement(1861887..1863050) Brucella suis 1330 1167629 NP_698907.1 CDS omp19 NC_004310.3 1863170 1863703 R identified by similarity to GP:954748; lipoprotein Omp19 complement(1863170..1863703) Brucella suis 1330 1167630 NP_698908.1 CDS BR1931 NC_004310.3 1863833 1864036 R hypothetical protein complement(1863833..1864036) Brucella suis 1330 1167631 NP_698909.1 CDS dapF NC_004310.3 1864067 1864978 D involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 1864067..1864978 Brucella suis 1330 1167632 NP_698910.1 CDS BR1933 NC_004310.3 1864978 1866261 D identified by similarity to GP:15076264; match to protein family HMM PF00919; match to protein family HMM PF04055; match to protein family HMM TIGR00089; match to protein family HMM TIGR01579; hypothetical protein 1864978..1866261 Brucella suis 1330 1167633 NP_698911.1 CDS ftsY NC_004310.3 1866289 1867680 D identified by similarity to EGAD:5681; match to protein family HMM PF00448; match to protein family HMM PF02881; match to protein family HMM TIGR00064; signal recognition particle-docking protein FtsY 1866289..1867680 Brucella suis 1330 1167634 NP_698912.1 CDS ispZ NC_004310.3 1867680 1868342 D Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 1867680..1868342 Brucella suis 1330 1167635 NP_698913.1 CDS BR1936 NC_004310.3 1868375 1869148 D identified by similarity to EGAD:35929; match to protein family HMM PF00753; hydroxyacylglutathione hydrolase 1868375..1869148 Brucella suis 1330 1167636 NP_698914.1 CDS BR1937 NC_004310.3 1869195 1869686 D hypothetical protein 1869195..1869686 Brucella suis 1330 1167637 NP_698915.1 CDS BR1938 NC_004310.3 1869751 1870056 R identified by similarity to OMNI:NTL02ML2661; hypothetical protein complement(1869751..1870056) Brucella suis 1330 1167638 NP_698916.1 CDS BR1939 NC_004310.3 1870168 1870584 R identified by similarity to EGAD:16514; match to protein family HMM PF00293; mutator mutT protein complement(1870168..1870584) Brucella suis 1330 1167639 NP_698917.1 CDS BR1940 NC_004310.3 1870581 1871372 R identified by match to protein family HMM PF00583; acetyltransferase complement(1870581..1871372) Brucella suis 1330 1167640 NP_698918.1 CDS argJ NC_004310.3 1871430 1872671 R bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; bifunctional ornithine acetyltransferase/N-acetylglutamate synthase complement(1871430..1872671) Brucella suis 1330 1167641 NP_698919.1 CDS BR1942 NC_004310.3 1872905 1873048 R hypothetical protein complement(1872905..1873048) Brucella suis 1330 1167642 NP_698920.1 CDS BR1943 NC_004310.3 1873109 1874104 R identified by similarity to EGAD:7364; match to protein family HMM PF00639; peptidyl-prolyl cis-trans isomerase complement(1873109..1874104) Brucella suis 1330 1167643 NP_698921.1 CDS BR1944 NC_004310.3 1874232 1874399 R hypothetical protein complement(1874232..1874399) Brucella suis 1330 1167644 NP_698922.1 CDS secA NC_004310.3 1874443 1877163 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1874443..1877163 Brucella suis 1330 1167645 NP_698923.1 CDS BR1946 NC_004310.3 1877191 1877331 D hypothetical protein 1877191..1877331 Brucella suis 1330 1167646 NP_698924.1 CDS BR1947 NC_004310.3 1877940 1879226 D identified by similarity to GP:14023746; hypothetical protein 1877940..1879226 Brucella suis 1330 1167647 NP_698925.1 CDS BR1948 NC_004310.3 1879395 1881029 D identified by match to protein family HMM PF00884; match to protein family HMM PF02418; hypothetical protein 1879395..1881029 Brucella suis 1330 1167648 NP_698926.1 CDS BR1949 NC_004310.3 1881383 1881484 D hypothetical protein 1881383..1881484 Brucella suis 1330 1167649 NP_698927.1 CDS BR1950 NC_004310.3 1881867 1882076 R hypothetical protein complement(1881867..1882076) Brucella suis 1330 1167651 NP_698928.1 CDS BR1951 NC_004310.3 1882197 1883180 R identified by match to protein family HMM PF00126; match to protein family HMM PF03466; LysR family transcriptional regulator complement(1882197..1883180) Brucella suis 1330 1167652 NP_698929.1 CDS BR1952 NC_004310.3 1883220 1883405 R hypothetical protein complement(1883220..1883405) Brucella suis 1330 1167653 NP_698930.1 CDS BR1953 NC_004310.3 1883471 1884316 D identified by match to protein family HMM PF00497; amino acid ABC transporter substrate-binding protein 1883471..1884316 Brucella suis 1330 1167654 NP_698931.1 CDS BR1955 NC_004310.3 1885107 1885829 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726; amino acid ABC transporter permease 1885107..1885829 Brucella suis 1330 1167656 NP_698932.1 CDS BR1956 NC_004310.3 1885826 1886641 D identified by match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1885826..1886641 Brucella suis 1330 1167657 NP_698933.1 CDS BR1957 NC_004310.3 1886662 1887675 D identified by match to protein family HMM PF00491; arginase 1886662..1887675 Brucella suis 1330 1167658 NP_698934.1 CDS aspA NC_004310.3 1887684 1889135 D catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 1887684..1889135 Brucella suis 1330 1167659 NP_698935.1 CDS BR1959 NC_004310.3 1889119 1889874 D identified by similarity to EGAD:31037; match to protein family HMM PF00005; amino acid ABC transporter ATP-binding protein 1889119..1889874 Brucella suis 1330 1167660 NP_698936.1 CDS BR1960 NC_004310.3 1889883 1890881 D identified by similarity to EGAD:14317; match to protein family HMM PF00710; L-asparaginase type II 1889883..1890881 Brucella suis 1330 1167661 NP_698937.1 CDS BR1961 NC_004310.3 1891018 1891701 R identified by match to protein family HMM PF00392; GntR family transcriptional regulator complement(1891018..1891701) Brucella suis 1330 1167662 NP_698938.1 CDS BR1962 NC_004310.3 1891725 1892714 R identified by similarity to SP:P43843; match to protein family HMM PF00710; asparaginase complement(1891725..1892714) Brucella suis 1330 1167663 NP_698939.1 CDS BR1963 NC_004310.3 1892792 1894099 D identified by match to protein family HMM PF00083; major facilitator family transporter 1892792..1894099 Brucella suis 1330 1167664 NP_698940.1 CDS BR1964 NC_004310.3 1894586 1894738 R hypothetical protein complement(1894586..1894738) Brucella suis 1330 1167665 NP_698941.1 CDS BR1965 NC_004310.3 1894785 1896068 R catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine; methionine gamma-lyase complement(1894785..1896068) Brucella suis 1330 1167666 NP_698942.1 CDS BR1966 NC_004310.3 1896248 1896697 R identified by match to protein family HMM PF00582; universal stress protein complement(1896248..1896697) Brucella suis 1330 1167667 NP_698943.1 CDS BR1968 NC_004310.3 1898009 1898257 R hypothetical protein complement(1898009..1898257) Brucella suis 1330 1167669 NP_698944.1 CDS hbd NC_004310.3 1898417 1899292 R converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; 3-hydroxybutyryl-CoA dehydrogenase complement(1898417..1899292) Brucella suis 1330 1167670 NP_698945.1 CDS etfA NC_004310.3 1899776 1900705 R identified by similarity to SP:P38974; match to protein family HMM PF00766; electron transfer flavoprotein subunit alpha complement(1899776..1900705) Brucella suis 1330 1167671 NP_698946.1 CDS etfB NC_004310.3 1900858 1901604 R identified by similarity to EGAD:17375; match to protein family HMM PF01012; electron transfer flavoprotein subunit beta complement(1900858..1901604) Brucella suis 1330 1167672 NP_698947.1 CDS BR1972 NC_004310.3 1901940 1902638 D identified by match to protein family HMM TIGR00364; exoenzyme S synthesis protein B 1901940..1902638 Brucella suis 1330 1167673 NP_698948.1 CDS BR1973 NC_004310.3 1902638 1903003 D identified by match to protein family HMM PF01242; 6-pyruvoyl tetrahydrobiopterin synthase 1902638..1903003 Brucella suis 1330 1167674 NP_698949.1 CDS BR1974 NC_004310.3 1903003 1903758 D identified by match to protein family HMM PF04055; radical activating enzyme 1903003..1903758 Brucella suis 1330 1167675 NP_698950.1 CDS BR1975 NC_004310.3 1903895 1904482 R identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; ATP:cob(I)alamin adenosyltransferase complement(1903895..1904482) Brucella suis 1330 1167676 NP_698951.1 CDS BR1976 NC_004310.3 1904484 1904651 R identified by similarity to OMNI:NTL02ML2682; hypothetical protein complement(1904484..1904651) Brucella suis 1330 1167677 NP_698952.1 CDS BR1977 NC_004310.3 1904717 1905559 R identified by match to protein family HMM PF00106; short chain dehydrogenase complement(1904717..1905559) Brucella suis 1330 1167678 NP_698953.1 CDS BR1978 NC_004310.3 1905717 1906577 D identified by match to protein family HMM PF03631; match to protein family HMM TIGR00765; ribonuclease BN 1905717..1906577 Brucella suis 1330 1167679 NP_698954.1 CDS BR1979 NC_004310.3 1906595 1907080 D identified by match to protein family HMM PF02639; hypothetical protein 1906595..1907080 Brucella suis 1330 1167680 NP_698955.1 CDS BR1980 NC_004310.3 1907088 1907804 R thiol:disulfide interchange protein complement(1907088..1907804) Brucella suis 1330 1167681 NP_698956.1 CDS argH NC_004310.3 1907858 1909258 D catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 1907858..1909258 Brucella suis 1330 1167682 NP_698957.1 CDS BR1982 NC_004310.3 1909363 1909551 D hypothetical protein 1909363..1909551 Brucella suis 1330 1167683 NP_698958.1 CDS lysA NC_004310.3 1909579 1910844 D identified by match to protein family HMM PF00278; match to protein family HMM PF02784; match to protein family HMM TIGR01048; diaminopimelate decarboxylase 1909579..1910844 Brucella suis 1330 1167684 NP_698959.1 CDS BR1984 NC_004310.3 1910943 1913588 D identified by similarity to GP:15075674; hypothetical protein 1910943..1913588 Brucella suis 1330 1167685 NP_698960.1 CDS hpt NC_004310.3 1913628 1914164 R Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively; hypoxanthine-guanine phosphoribosyltransferase complement(1913628..1914164) Brucella suis 1330 1167686 NP_698961.1 CDS BR1986 NC_004310.3 1914313 1915092 D identified by similarity to GP:15075687; hypothetical protein 1914313..1915092 Brucella suis 1330 1167687 NP_698962.1 CDS hisC NC_004310.3 1915246 1916343 D catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 1915246..1916343 Brucella suis 1330 1167688 NP_698963.1 CDS tyrC NC_004310.3 1916348 1917313 D dual function enzyme catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate and the formation of tyrosine from arogenate; cyclohexadienyl dehydrogenase 1916348..1917313 Brucella suis 1330 1167689 NP_698964.1 CDS BR1989 NC_004310.3 1917282 1918301 R identified by similarity to OMNI:NTL02ML2723; hypothetical protein complement(1917282..1918301) Brucella suis 1330 1167690 NP_698965.1 CDS BR1990 NC_004310.3 1918321 1918524 R hypothetical protein complement(1918321..1918524) Brucella suis 1330 1167691 NP_698966.1 CDS BR1991 NC_004310.3 1918513 1919073 D identified by similarity to SP:P39163; match to protein family HMM PF04752; cation transport protein 1918513..1919073 Brucella suis 1330 1167692 NP_698967.1 CDS BR1992 NC_004310.3 1919406 1919696 D identified by similarity to EGAD:140445; match to protein family HMM PF02325; hypothetical protein 1919406..1919696 Brucella suis 1330 1167694 NP_698968.1 CDS ppa NC_004310.3 1919867 1920397 R catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase complement(1919867..1920397) Brucella suis 1330 1167695 NP_698969.1 CDS BR1994 NC_004310.3 1920550 1921332 R identified by match to protein family HMM PF01553; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1920550..1921332) Brucella suis 1330 1167696 NP_698970.1 CDS BR1995 NC_004310.3 1921511 1922149 R identified by similarity to GP:15075681; hypothetical protein complement(1921511..1922149) Brucella suis 1330 1167697 NP_698971.1 CDS BR1996 NC_004310.3 1922410 1923411 R identified by similarity to OMNI:NTL02ML2714; hypothetical protein complement(1922410..1923411) Brucella suis 1330 1167698 NP_698972.1 CDS ftsE NC_004310.3 1923404 1924063 R identified by similarity to EGAD:7038; match to protein family HMM PF00005; cell division ABC transporter ATP-binding protein FtsE complement(1923404..1924063) Brucella suis 1330 1167699 NP_698973.1 CDS BR1998 NC_004310.3 1924068 1924250 R hypothetical protein complement(1924068..1924250) Brucella suis 1330 1167700 NP_698974.1 CDS BR1999 NC_004310.3 1924319 1924738 D hypothetical protein 1924319..1924738 Brucella suis 1330 1167701 NP_698975.1 CDS BR2000 NC_004310.3 1924775 1924876 R hypothetical protein complement(1924775..1924876) Brucella suis 1330 1167702 NP_698976.1 CDS aqpZ NC_004310.3 1925122 1925808 D porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure; aquaporin Z 1925122..1925808 Brucella suis 1330 1167703 NP_698977.1 CDS BR2002 NC_004310.3 1925809 1925940 R hypothetical protein complement(1925809..1925940) Brucella suis 1330 1167704 NP_698978.1 CDS BR2003 NC_004310.3 1926192 1926884 D identified by similarity to GP:15157980; hypothetical protein 1926192..1926884 Brucella suis 1330 1167705 NP_698979.1 CDS xth-2 NC_004310.3 1926987 1927793 D identified by similarity to OMNI:NTL02ML3264; match to protein family HMM PF03372; match to protein family HMM TIGR00633; exodeoxyribonuclease III 1926987..1927793 Brucella suis 1330 1167706 NP_698980.1 CDS BR2005 NC_004310.3 1927799 1928260 R identified by match to protein family HMM PF00027; cyclic nucleotide-binding protein complement(1927799..1928260) Brucella suis 1330 1167707 NP_698981.1 CDS BR2006 NC_004310.3 1928295 1928978 R identified by similarity to OMNI:NTL02ML3262; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator complement(1928295..1928978) Brucella suis 1330 1167708 NP_698982.1 CDS BR2007 NC_004310.3 1929228 1929731 D identified by similarity to GP:14024337; hypothetical protein 1929228..1929731 Brucella suis 1330 1167709 NP_698983.1 CDS BR2008 NC_004310.3 1929792 1930091 D hypothetical protein 1929792..1930091 Brucella suis 1330 1167710 NP_698984.1 CDS BR2009 NC_004310.3 1930120 1931643 R intimin/invasin family protein complement(1930120..1931643) Brucella suis 1330 1167711 NP_698985.1 CDS BR2010 NC_004310.3 1931640 1932719 R hypothetical protein complement(1931640..1932719) Brucella suis 1330 1167712 NP_698986.1 CDS BR2011 NC_004310.3 1933046 1933435 D hypothetical protein 1933046..1933435 Brucella suis 1330 1167713 NP_698987.1 CDS BR2012 NC_004310.3 1933522 1935078 R hypothetical protein complement(1933522..1935078) Brucella suis 1330 1167714 NP_698988.1 CDS BR2013 NC_004310.3 1935263 1940044 D identified by similarity to GP:15162141; match to protein family HMM PF03797; match to protein family HMM TIGR01414; match to protein family HMM TIGR01612; outer membrane autotransporter 1935263..1940044 Brucella suis 1330 1167715 NP_698989.1 CDS BR2014 NC_004310.3 1940185 1940856 R identified by similarity to GP:15075693; match to protein family HMM PF02592; match to protein family HMM TIGR00697; hypothetical protein complement(1940185..1940856) Brucella suis 1330 1167716 NP_698990.1 CDS rpmB NC_004310.3 1940936 1941229 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1940936..1941229) Brucella suis 1330 1167717 NP_698991.1 CDS BR2016 NC_004310.3 1941591 1942406 D identified by similarity to OMNI:NTL02ML2738; hypothetical protein 1941591..1942406 Brucella suis 1330 1167718 NP_698992.1 CDS BR2017 NC_004310.3 1942518 1942940 R identified by match to protein family HMM PF00376; MerR family transcriptional regulator complement(1942518..1942940) Brucella suis 1330 1167719 NP_698993.1 CDS cadA-1 NC_004310.3 1943029 1945473 D identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525; cadmium-translocating P-type ATPase 1943029..1945473 Brucella suis 1330 1167720 NP_698994.1 CDS BR2019 NC_004310.3 1945880 1946629 D identified by similarity to GP:15141324; hypothetical protein 1945880..1946629 Brucella suis 1330 1167721 NP_698995.1 CDS BR2020 NC_004310.3 1946656 1947741 D hypothetical protein 1946656..1947741 Brucella suis 1330 1167722 NP_698996.1 CDS BR2021 NC_004310.3 1947914 1949815 R identified by similarity to SP:P29934; match to protein family HMM TIGR01651; cobalamin biosynthesis protein complement(1947914..1949815) Brucella suis 1330 1167723 NP_698997.1 CDS BR2022 NC_004310.3 1949923 1950909 R identified by similarity to SP:P29933; match to protein family HMM TIGR01650; cobalamin biosynthesis protein complement(1949923..1950909) Brucella suis 1330 1167724 NP_698998.1 CDS BR2023 NC_004310.3 1950988 1951218 D hypothetical protein 1950988..1951218 Brucella suis 1330 1167725 NP_698999.1 CDS BR2024 NC_004310.3 1951196 1951825 R identified by match to protein family HMM PF00226; DnaJ domain-containing protein complement(1951196..1951825) Brucella suis 1330 1167726 NP_699000.1 CDS BR2025 NC_004310.3 1951822 1952019 R hypothetical protein complement(1951822..1952019) Brucella suis 1330 1167727 NP_699001.1 CDS bolA NC_004310.3 1952012 1952326 D identified by similarity to SP:P15298; match to protein family HMM PF01722; bolA protein 1952012..1952326 Brucella suis 1330 1167728 NP_699002.1 CDS BR2027 NC_004310.3 1952351 1953658 R identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471; CBS domain-containing protein complement(1952351..1953658) Brucella suis 1330 1167729 NP_699003.1 CDS aroB NC_004310.3 1953722 1954858 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1953722..1954858) Brucella suis 1330 1167730 NP_699004.1 CDS aroK NC_004310.3 1954951 1955553 R catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase complement(1954951..1955553) Brucella suis 1330 1167731 NP_699005.1 CDS BR2030 NC_004310.3 1955678 1955884 D hypothetical protein 1955678..1955884 Brucella suis 1330 1167732 NP_699006.1 CDS xerD NC_004310.3 1955887 1956810 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD 1955887..1956810 Brucella suis 1330 1167733 NP_699007.1 CDS accA NC_004310.3 1956949 1957902 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-CoA carboxylase carboxyltransferase subunit alpha 1956949..1957902 Brucella suis 1330 1167734 NP_699008.1 CDS BR2033 NC_004310.3 1958124 1959335 D identified by similarity to GP:15159690; lipoprotein 1958124..1959335 Brucella suis 1330 1167735 NP_699009.1 CDS BR2034 NC_004310.3 1959314 1959571 D identified by similarity to GP:15075708; match to protein family HMM PF01206; hypothetical protein 1959314..1959571 Brucella suis 1330 1167736 NP_699010.1 CDS BR2035 NC_004310.3 1959589 1960761 R identified by match to protein family HMM PF02492; cobalamin synthesis protein/P47K family protein complement(1959589..1960761) Brucella suis 1330 1167737 NP_699011.1 CDS BR2036 NC_004310.3 1960763 1961878 R identified by match to protein family HMM PF00768; D-alanyl-D-alanine carboxypeptidase complement(1960763..1961878) Brucella suis 1330 1167738 NP_699012.1 CDS BR2037 NC_004310.3 1962173 1963336 D identified by match to protein family HMM PF01546; match to protein family HMM TIGR01891; M20/M25/M40 family peptidase 1962173..1963336 Brucella suis 1330 1167739 NP_699013.1 CDS BR2038 NC_004310.3 1963333 1963467 D hypothetical protein 1963333..1963467 Brucella suis 1330 1167740 NP_699014.1 CDS BR2039 NC_004310.3 1963535 1964299 R identified by similarity to EGAD:23256; match to protein family HMM PF00106; glucose 1-dehydrogenase complement(1963535..1964299) Brucella suis 1330 1167742 NP_699015.1 CDS BR2040 NC_004310.3 1964407 1964841 D identified by similarity to GP:15157579; match to protein family HMM PF04828; hypothetical protein 1964407..1964841 Brucella suis 1330 1167743 NP_699016.1 CDS BR2041 NC_004310.3 1964991 1965335 D identified by similarity to OMNI:NTL03PA01934; hypothetical protein 1964991..1965335 Brucella suis 1330 1167744 NP_699017.1 CDS BR2042 NC_004310.3 1965405 1967039 R identified by similarity to EGAD:149670; match to protein family HMM PF00732; match to protein family HMM PF05199; L-sorbose dehydrogenase complement(1965405..1967039) Brucella suis 1330 1167745 NP_699018.1 CDS fabG NC_004310.3 1967050 1967814 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1967050..1967814) Brucella suis 1330 1167746 NP_699019.1 CDS BR2044 NC_004310.3 1967811 1969295 R GMC family oxidoreductase complement(1967811..1969295) Brucella suis 1330 1167747 NP_699020.1 CDS BR2045 NC_004310.3 1969308 1970828 R identified by similarity to EGAD:149672; match to protein family HMM PF00171; L-sorbosone dehydrogenase, NAD(P) dependent complement(1969308..1970828) Brucella suis 1330 1167748 NP_699021.1 CDS BR2046 NC_004310.3 1970822 1971598 R identified by match to protein family HMM PF00378; enoyl-CoA hydratase complement(1970822..1971598) Brucella suis 1330 1167749 NP_699022.1 CDS BR2047 NC_004310.3 1971600 1973201 R identified by match to protein family HMM PF01144; acetyl-CoA-transferase subunit complement(1971600..1973201) Brucella suis 1330 1167750 NP_699023.1 CDS BR2048 NC_004310.3 1973207 1974208 R identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase complement(1973207..1974208) Brucella suis 1330 1167751 NP_699024.1 CDS BR2049 NC_004310.3 1974187 1975245 R identified by match to protein family HMM PF00356; match to protein family HMM PF00532; LacI family transcription regulator complement(1974187..1975245) Brucella suis 1330 1167752 NP_699025.1 CDS BR2050 NC_004310.3 1975496 1976665 D identified by similarity to GP:15076333; hypothetical protein 1975496..1976665 Brucella suis 1330 1167753 NP_699026.1 CDS BR2051 NC_004310.3 1976699 1977721 R identified by match to protein family HMM PF00296; luciferase complement(1976699..1977721) Brucella suis 1330 1167754 NP_699027.1 CDS BR2052 NC_004310.3 1977718 1977927 R hypothetical protein complement(1977718..1977927) Brucella suis 1330 1167755 NP_699028.1 CDS BR2053 NC_004310.3 1977990 1978955 D identified by similarity to GP:15076239; match to protein family HMM PF04392; ABC transporter periplasmic substrate-binding protein 1977990..1978955 Brucella suis 1330 1167756 NP_699029.1 CDS BR2054 NC_004310.3 1979159 1979419 R hypothetical protein complement(1979159..1979419) Brucella suis 1330 1167757 NP_699030.1 CDS BR2055 NC_004310.3 1979599 1980483 D identified by match to protein family HMM PF02653; branched-chain amino acid ABC transporter permease 1979599..1980483 Brucella suis 1330 1167758 NP_699031.1 CDS BR2056 NC_004310.3 1980480 1981274 D identified by match to protein family HMM PF00005; ABC transporter ATP-binding protein 1980480..1981274 Brucella suis 1330 1167759 NP_699032.1 CDS holA NC_004310.3 1981436 1982479 D required for the assembly and function of the DNAX complex which are required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 1981436..1982479 Brucella suis 1330 1167760 NP_699033.1 CDS parB NC_004310.3 1982573 1983454 R identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; chromosome partitioning protein ParB complement(1982573..1983454) Brucella suis 1330 1167761 NP_699034.1 CDS parA NC_004310.3 1983498 1984295 R identified by similarity to SP:O05189; match to protein family HMM PF00991; chromosome partitioning protein ParA complement(1983498..1984295) Brucella suis 1330 1167762 NP_699035.1 CDS gidB NC_004310.3 1984348 1984989 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB complement(1984348..1984989) Brucella suis 1330 1167763 NP_699036.1 CDS gidA NC_004310.3 1984986 1986896 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA complement(1984986..1986896) Brucella suis 1330 1167764 NP_699037.1 CDS trmE NC_004310.3 1987123 1988451 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(1987123..1988451) Brucella suis 1330 1167765 NP_699038.1 CDS BR2063 NC_004310.3 1988566 1990566 D identified by similarity to GP:14024528; match to protein family HMM PF03190; hypothetical protein 1988566..1990566 Brucella suis 1330 1167766 NP_699039.1 CDS rho NC_004310.3 1990651 1991916 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(1990651..1991916) Brucella suis 1330 1167767 NP_699040.1 CDS BR2065 NC_004310.3 1992298 1992834 R identified by similarity to OMNI:NTL02ML3455; match to protein family HMM PF03653; match to protein family HMM TIGR00701; hypothetical protein complement(1992298..1992834) Brucella suis 1330 1167768 NP_699041.1 CDS hemE NC_004310.3 1992831 1993856 R catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase complement(1992831..1993856) Brucella suis 1330 1167769 NP_699042.1 CDS BR2067 NC_004310.3 1994309 1995148 D identified by similarity to GP:14024532; match to protein family HMM PF03618; hypothetical protein 1994309..1995148 Brucella suis 1330 1167770 NP_699043.1 CDS maf NC_004310.3 1995145 1995744 D Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 1995145..1995744 Brucella suis 1330 1167771 NP_699044.1 CDS aroE NC_004310.3 1995752 1996606 D AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 1995752..1996606 Brucella suis 1330 1167772 NP_699045.1 CDS coaE NC_004310.3 1996603 1997205 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 1996603..1997205 Brucella suis 1330 1167773 NP_699046.1 CDS dnaQ NC_004310.3 1997247 1997951 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 1997247..1997951 Brucella suis 1330 1167774 NP_699047.1 CDS secB NC_004310.3 1998010 1998501 R molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB complement(1998010..1998501) Brucella suis 1330 1167775 NP_699048.1 CDS fxsA NC_004310.3 1998621 1999118 R F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; FxsA complement(1998621..1999118) Brucella suis 1330 1167776 NP_699049.1 CDS BR2074 NC_004310.3 1999323 2000030 D identified by similarity to GP:15154866; hypothetical protein 1999323..2000030 Brucella suis 1330 1167777 NP_699050.1 CDS BR2075 NC_004310.3 2000094 2001203 D identified by match to protein family HMM PF03562; transglycosylase-like protein 2000094..2001203 Brucella suis 1330 1167778 NP_699051.1 CDS BR2076 NC_004310.3 2001209 2001811 D identified by match to protein family HMM PF01713; Smr family protein 2001209..2001811 Brucella suis 1330 1167779 NP_699052.1 CDS BR2077 NC_004310.3 2001808 2002188 D identified by similarity to GP:15154869; match to protein family HMM PF01381; hypothetical protein 2001808..2002188 Brucella suis 1330 1167780 NP_699053.1 CDS BR2078 NC_004310.3 2002197 2003126 R identified by similarity to GP:15154911; hypothetical protein complement(2002197..2003126) Brucella suis 1330 1167781 NP_699054.1 CDS hslU NC_004310.3 2003363 2004667 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU complement(2003363..2004667) Brucella suis 1330 1167782 NP_699055.1 CDS hslV NC_004310.3 2004741 2005295 R heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit complement(2004741..2005295) Brucella suis 1330 1167783 NP_699056.1 CDS hisB NC_004310.3 2005592 2006200 D catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 2005592..2006200 Brucella suis 1330 1167784 NP_699057.1 CDS BR2082 NC_004310.3 2006312 2006821 D identified by similarity to GP:15072982; hypothetical protein 2006312..2006821 Brucella suis 1330 1167785 NP_699058.1 CDS hisH NC_004310.3 2006824 2007474 D with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 2006824..2007474 Brucella suis 1330 1167786 NP_699059.1 CDS hisA NC_004310.3 2007479 2008210 D catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 2007479..2008210 Brucella suis 1330 1167787 NP_699060.1 CDS hisF NC_004310.3 2008207 2008992 D catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 2008207..2008992 Brucella suis 1330 1167788 NP_699061.1 CDS hisE NC_004310.3 2009128 2009451 D catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; phosphoribosyl-ATP pyrophosphatase 2009128..2009451 Brucella suis 1330 1167789 NP_699062.1 CDS coaA NC_004310.3 2009466 2010434 D catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2009466..2010434 Brucella suis 1330 1167790 NP_699063.1 CDS BR2088 NC_004310.3 2010497 2011033 R identified by match to protein family HMM PF00472; peptidyl-tRNA hydrolase domain-containing protein complement(2010497..2011033) Brucella suis 1330 1167791 NP_699064.1 CDS pckA NC_004310.3 2011046 2012656 R PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase complement(2011046..2012656) Brucella suis 1330 1167792 NP_699065.1 CDS BR2090 NC_004310.3 2013059 2013778 D identified by similarity to GP:2947107; match to protein family HMM PF00072; match to protein family HMM PF00486; DNA-binding response regulator BvrR 2013059..2013778 Brucella suis 1330 1167793 NP_699066.1 CDS BR2091 NC_004310.3 2013889 2015694 D identified by similarity to GP:2947211; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; sensor histidine kinase BvrS 2013889..2015694 Brucella suis 1330 1167794 NP_699067.1 CDS BR2092 NC_004310.3 2015720 2016199 D identified by similarity to GP:14024999; hypothetical protein 2015720..2016199 Brucella suis 1330 1167795 NP_699068.1 CDS BR2093 NC_004310.3 2016174 2016449 D hypothetical protein 2016174..2016449 Brucella suis 1330 1167796 NP_699069.1 CDS BR2094 NC_004310.3 2016451 2016852 D identified by similarity to EGAD:7066; match to protein family HMM PF03610; PTS system, IIA component 2016451..2016852 Brucella suis 1330 1167797 NP_699070.1 CDS ptsH NC_004310.3 2016856 2017170 D identified by similarity to SP:P08877; match to protein family HMM PF00381; match to protein family HMM TIGR01003; phosphocarrier protein HPr 2016856..2017170 Brucella suis 1330 1167798 NP_699071.1 CDS BR2096 NC_004310.3 2017234 2017551 D hypothetical protein 2017234..2017551 Brucella suis 1330 1167799 NP_699072.1 CDS ahcY NC_004310.3 2017548 2018948 D catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine; S-adenosyl-L-homocysteine hydrolase 2017548..2018948 Brucella suis 1330 1167800 NP_699073.1 CDS BR2098 NC_004310.3 2019136 2019345 D hypothetical protein 2019136..2019345 Brucella suis 1330 1167801 NP_699074.1 CDS BR2099 NC_004310.3 2019333 2021912 D identified by match to protein family HMM PF00512; match to protein family HMM PF02518; sensory box histidine kinase 2019333..2021912 Brucella suis 1330 1167802 NP_699075.1 CDS BR2100 NC_004310.3 2021921 2023462 D identified by similarity to OMNI:NTL02ML3919; match to protein family HMM PF02367; match to protein family HMM TIGR00150; hypothetical protein 2021921..2023462 Brucella suis 1330 1167803 NP_699076.1 CDS BR2101 NC_004310.3 2023449 2024168 D identified by similarity to GP:14024993; match to protein family HMM PF00483; nucleotidyltransferase 2023449..2024168 Brucella suis 1330 1167804 NP_699077.1 CDS BR2102 NC_004310.3 2024183 2027341 D identified by similarity to OMNI:NTL02ML3917; hypothetical protein 2024183..2027341 Brucella suis 1330 1167805 NP_699078.1 CDS BR2103 NC_004310.3 2027338 2030880 D identified by similarity to OMNI:CC3538; match to protein family HMM PF00580; UvrD/REP helicase 2027338..2030880 Brucella suis 1330 1167806 NP_699079.1 CDS BR2104 NC_004310.3 2030858 2030995 D hypothetical protein 2030858..2030995 Brucella suis 1330 1167807 NP_699080.1 CDS trx-1 NC_004310.3 2031062 2031385 D identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068; thioredoxin 2031062..2031385 Brucella suis 1330 1167808 NP_699081.1 CDS folC NC_004310.3 2031599 2032927 R identified by match to protein family HMM TIGR01499; FolC bifunctional protein complement(2031599..2032927) Brucella suis 1330 1167809 NP_699082.1 CDS accD NC_004310.3 2032930 2033835 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta complement(2032930..2033835) Brucella suis 1330 1167810 NP_699083.1 CDS trpA NC_004310.3 2033896 2034735 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(2033896..2034735) Brucella suis 1330 1167811 NP_699084.1 CDS BR2109 NC_004310.3 2034732 2035079 R hypothetical protein complement(2034732..2035079) Brucella suis 1330 1167812 NP_699085.1 CDS trpB NC_004310.3 2035202 2036422 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(2035202..2036422) Brucella suis 1330 1167813 NP_699086.1 CDS trpF NC_004310.3 2036442 2037110 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(2036442..2037110) Brucella suis 1330 1167814 NP_699087.1 CDS BR2112 NC_004310.3 2037149 2037784 R identified by similarity to OMNI:VC1698; hypothetical protein complement(2037149..2037784) Brucella suis 1330 1167815 NP_699088.1 CDS BR2113 NC_004310.3 2037781 2038542 R identified by similarity to GP:15154876; match to protein family HMM PF01863; hypothetical protein complement(2037781..2038542) Brucella suis 1330 1167816 NP_699089.1 CDS BR2114 NC_004310.3 2038651 2039097 R identified by similarity to GP:15072953; hypothetical protein complement(2038651..2039097) Brucella suis 1330 1167817 NP_699090.1 CDS BR2115 NC_004310.3 2039279 2040430 R identified by match to protein family HMM PF03594; match to protein family HMM TIGR00843; benzoate transport protein complement(2039279..2040430) Brucella suis 1330 1167818 NP_699091.1 CDS BR2116 NC_004310.3 2040444 2041235 R identified by similarity to OMNI:NTL02ML3900; hypothetical protein complement(2040444..2041235) Brucella suis 1330 1167819 NP_699092.1 CDS infC NC_004310.3 2041667 2042071 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2041667..2042071 Brucella suis 1330 1167820 NP_699093.1 CDS BR2118 NC_004310.3 2042200 2042814 D identified by similarity to EGAD:42737; nickel-cobalt-cadmium resistance protein 2042200..2042814 Brucella suis 1330 1167821 NP_699094.1 CDS rpmI NC_004310.3 2043081 2043281 D identified by similarity to SP:P55874; match to protein family HMM PF01632; match to protein family HMM TIGR00001; 50S ribosomal protein L35 2043081..2043281 Brucella suis 1330 1167822 NP_699095.1 CDS rplT NC_004310.3 2043309 2043713 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2043309..2043713 Brucella suis 1330 1167823 NP_699096.1 CDS BR2121 NC_004310.3 2043812 2044654 D identified by similarity to GP:15155150; hypothetical protein 2043812..2044654 Brucella suis 1330 1167824 NP_699097.1 CDS pheS NC_004310.3 2044743 2045852 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 2044743..2045852 Brucella suis 1330 1167825 NP_699098.1 CDS pheT NC_004310.3 2045874 2048288 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 2045874..2048288 Brucella suis 1330 1167826 NP_699099.1 CDS BR2124 NC_004310.3 2048358 2049344 D identified by match to protein family HMM PF01408; match to protein family HMM PF02894; Gfo/Idh/MocA family oxidoreductase 2048358..2049344 Brucella suis 1330 1167827 NP_699100.1 CDS dnaK NC_004310.3 2049570 2051483 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 2049570..2051483 Brucella suis 1330 1167828 NP_699101.1 CDS dnaJ NC_004310.3 2051728 2052861 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 2051728..2052861 Brucella suis 1330 1167829 NP_699102.1 CDS pmtA NC_004310.3 2052982 2053578 D identified by similarity to GP:9966391; phospholipid N-methyltransferase 2052982..2053578 Brucella suis 1330 1167830 NP_699103.1 CDS pyrF NC_004310.3 2053788 2054504 D OMP decarboxylase; OMPDCase; OMPdecase; type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 2053788..2054504 Brucella suis 1330 1167831 NP_699104.1 CDS BR2129 NC_004310.3 2054553 2054840 D identified by similarity to GP:15155195; hypothetical protein 2054553..2054840 Brucella suis 1330 1167832 NP_699105.1 CDS BR2130 NC_004310.3 2054878 2056065 R identified by similarity to OMNI:NTL02ML3653; match to protein family HMM PF03758; Smp-30/Cgr1 family protein complement(2054878..2056065) Brucella suis 1330 1167833 NP_699106.1 CDS gshb NC_004310.3 2056001 2056939 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 2056001..2056939 Brucella suis 1330 1167834 NP_699107.1 CDS BR2132 NC_004310.3 2057049 2058581 D identified by match to protein family HMM PF01078; match to protein family HMM TIGR00368; Mg chelatase-like protein 2057049..2058581 Brucella suis 1330 1167835 NP_699108.1 CDS BR2133 NC_004310.3 2058630 2059250 R identified by similarity to GP:15074346; hypothetical protein complement(2058630..2059250) Brucella suis 1330 1167836 NP_699109.1 CDS BR2134 NC_004310.3 2059511 2059624 D hypothetical protein 2059511..2059624 Brucella suis 1330 1167837 NP_699110.1 CDS BR2135 NC_004310.3 2059697 2060053 R identified by match to protein family HMM PF03330; match to protein family HMM TIGR00413; rare lipoprotein A family protein complement(2059697..2060053) Brucella suis 1330 1167838 NP_699111.1 CDS BR2136 NC_004310.3 2060209 2060430 D hypothetical protein 2060209..2060430 Brucella suis 1330 1167839 NP_699112.1 CDS BR2137 NC_004310.3 2060663 2061013 D identified by similarity to EGAD:35582; hypothetical protein 2060663..2061013 Brucella suis 1330 1167840 NP_699113.1 CDS BR2138 NC_004310.3 2061168 2062214 D phosphate ABC transporter phosphate-binding protein 2061168..2062214 Brucella suis 1330 1167841 NP_699114.1 CDS pstC NC_004310.3 2062356 2063846 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR02138; phosphate ABC transporter permease 2062356..2063846 Brucella suis 1330 1167842 NP_699115.1 CDS BR2140 NC_004310.3 2063846 2065156 D identified by match to protein family HMM PF00528; match to protein family HMM TIGR00974; phosphate ABC transporter permease 2063846..2065156 Brucella suis 1330 1167843 NP_699116.1 CDS pstB NC_004310.3 2065221 2065994 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2065221..2065994 Brucella suis 1330 1167844 NP_699117.1 CDS phoU NC_004310.3 2066060 2066782 D identified by similarity to EGAD:14202; match to protein family HMM PF01895; match to protein family HMM TIGR02135; phosphate transport system regulatory protein PhoU 2066060..2066782 Brucella suis 1330 1167845 NP_699118.1 CDS phoB NC_004310.3 2066900 2067586 D identified by similarity to EGAD:5895; match to protein family HMM PF00072; match to protein family HMM PF00486; match to protein family HMM TIGR02154; phosphate regulon transcriptional regulatory protein Phob 2066900..2067586 Brucella suis 1330 1167846 NP_699119.1 CDS BR2144 NC_004310.3 2067942 2068100 R hypothetical protein complement(2067942..2068100) Brucella suis 1330 1167847 NP_699120.1 CDS BR2145 NC_004310.3 2068172 2069152 D identified by similarity to OMNI:NTL02ML4270; lipoprotein 2068172..2069152 Brucella suis 1330 1167848 NP_699121.1 CDS BR2146 NC_004310.3 2069262 2069585 R identified by similarity to GP:15155785; lipoprotein complement(2069262..2069585) Brucella suis 1330 1167849 NP_699122.1 CDS BR2147 NC_004310.3 2069575 2069679 R hypothetical protein complement(2069575..2069679) Brucella suis 1330 1167850 NP_699123.1 CDS pepS NC_004310.3 2069662 2070915 D identified by similarity to SP:Q9X4A7; match to protein family HMM PF02073; aminopeptidase 2069662..2070915 Brucella suis 1330 1167851 NP_699124.1 CDS BR2149 NC_004310.3 2071076 2071573 R binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; DNA starvation/stationary phase protection protein Dps complement(2071076..2071573) Brucella suis 1330 1167852 NP_699125.1 CDS BR2150 NC_004310.3 2071760 2072545 D identified by match to protein family HMM PF00814; protease 2071760..2072545 Brucella suis 1330 1167853 NP_699126.1 CDS BR2151 NC_004310.3 2072550 2073050 D identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575; acetyltransferase 2072550..2073050 Brucella suis 1330 1167854 NP_699127.1 CDS BR2152 NC_004310.3 2073047 2073850 D identified by match to protein family HMM PF01553; acyltransferase 2073047..2073850 Brucella suis 1330 1167855 NP_699128.1 CDS BR2153 NC_004310.3 2073908 2075311 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 2073908..2075311 Brucella suis 1330 1167856 NP_699129.1 CDS BR2154 NC_004310.3 2075409 2075501 R hypothetical protein complement(2075409..2075501) Brucella suis 1330 1167857 NP_699130.1 CDS BR2155 NC_004310.3 2075548 2076531 D identified by match to protein family HMM PF02562; PhoH family protein 2075548..2076531 Brucella suis 1330 1167858 NP_699131.1 CDS BR2156 NC_004310.3 2076697 2077173 D identified by similarity to OMNI:NTL02ML4294; match to protein family HMM PF02130; match to protein family HMM TIGR00043; hypothetical protein 2076697..2077173 Brucella suis 1330 1167859 NP_699132.1 CDS BR2157 NC_004310.3 2077266 2078294 D identified by similarity to OMNI:VC0959; match to protein family HMM PF00571; match to protein family HMM PF03471; CBS domain-containing protein 2077266..2078294 Brucella suis 1330 1167860 NP_699133.1 CDS lnt NC_004310.3 2078291 2079889 D Transfers the fatty acyl group on membrane lipoproteins; apolipoprotein N-acyltransferase 2078291..2079889 Brucella suis 1330 1167861 NP_699134.1 CDS BR2159 NC_004310.3 2080036 2080449 D identified by match to protein family HMM PF01381; Cro/CI family transcriptional regulator 2080036..2080449 Brucella suis 1330 1167862 NP_699135.1 CDS metK NC_004310.3 2080676 2081941 D methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 2080676..2081941 Brucella suis 1330 1167863 NP_699136.1 CDS trmB NC_004310.3 2081950 2082651 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 2081950..2082651 Brucella suis 1330 1167864 NP_699137.1 CDS BR2162 NC_004310.3 2082831 2083490 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 2082831..2083490 Brucella suis 1330 1167865 NP_699138.1 CDS nusA NC_004310.3 2083543 2085156 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 2083543..2085156 Brucella suis 1330 1167866 NP_699139.1 CDS BR2164 NC_004310.3 2085538 2086140 D identified by similarity to GP:15073167; match to protein family HMM PF04296; hypothetical protein 2085538..2086140 Brucella suis 1330 1167867 NP_699140.1 CDS infB NC_004310.3 2086278 2089157 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 2086278..2089157 Brucella suis 1330 1167868 NP_699141.1 CDS rbfA NC_004310.3 2089423 2089875 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 2089423..2089875 Brucella suis 1330 1167869 YP_089635.1 CDS truB NC_004310.3 2089879 2090853 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 2089879..2090853 Brucella suis 1330 1167870 NP_699142.1 CDS rpsO NC_004310.3 2091024 2091293 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 2091024..2091293 Brucella suis 1330 1167871 NP_699143.1 CDS pnp NC_004310.3 2091577 2093721 D identified by similarity to SP:P05055; match to protein family HMM PF00013; match to protein family HMM PF00575; match to protein family HMM PF01138; match to protein family HMM PF03725; match to protein family HMM PF03726; polynucleotide phosphorylase 2091577..2093721 Brucella suis 1330 1167872 NP_699144.1 CDS BR2170 NC_004310.3 2093832 2094854 D identified by match to protein family HMM PF05175; methyltransferase 2093832..2094854 Brucella suis 1330 1167873 NP_699145.1 CDS fabI-2 NC_004310.3 2094902 2095720 R Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase complement(2094902..2095720) Brucella suis 1330 1167874 NP_699146.1 CDS fabB NC_004310.3 2095735 2096958 R FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(2095735..2096958) Brucella suis 1330 1167875 NP_699147.1 CDS fabA NC_004310.3 2097124 2097642 R catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP; 3-hydroxydecanoyl-ACP dehydratase complement(2097124..2097642) Brucella suis 1330 1167876 NP_699148.1 CDS BR2174 NC_004310.3 2097889 2098332 D identified by match to protein family HMM PF01475; ferric uptake regulator family protein 2097889..2098332 Brucella suis 1330 1167877 NP_699149.1 CDS BR2175 NC_004310.3 2098498 2099277 D identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363; YaeC family lipoprotein 2098498..2099277 Brucella suis 1330 1167878 NP_699150.1 CDS BR2176 NC_004310.3 2099322 2099867 R identified by similarity to GP:14025396; hypothetical protein complement(2099322..2099867) Brucella suis 1330 1167879 NP_699151.1 CDS BR2177 NC_004310.3 2100218 2101222 D Involved in the metabolism of aromatic amino acids; 2-hydroxyacid dehydrogenase 2100218..2101222 Brucella suis 1330 1167880 NP_699152.1 CDS BR2178 NC_004310.3 2101247 2101948 R hydrolase complement(2101247..2101948) Brucella suis 1330 1167881 NP_699153.1 CDS BR2179 NC_004310.3 2101970 2102842 R identified by match to protein family HMM PF00877; NLP/P60 family protein complement(2101970..2102842) Brucella suis 1330 1167882 NP_699154.1 CDS BR2180 NC_004310.3 2102839 2103189 R identified by similarity to GP:15073078; transcriptional regulator complement(2102839..2103189) Brucella suis 1330 1167883 NP_699155.1 CDS BR2181 NC_004310.3 2103264 2104646 R identified by match to protein family HMM PF00883; cytosol aminopeptidase complement(2103264..2104646) Brucella suis 1330 1167884 NP_699156.1 CDS BR2182 NC_004310.3 2104806 2104985 R identified by similarity to OMNI:CC2948; pilus biosynthesis protein-like protein complement(2104806..2104985) Brucella suis 1330 1167885 NP_699157.1 CDS mutM NC_004310.3 2105205 2106086 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2105205..2106086 Brucella suis 1330 1167886 NP_699158.1 CDS BR2184 NC_004310.3 2106213 2106986 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2106213..2106986 Brucella suis 1330 1167887 NP_699159.1 CDS rpsT NC_004310.3 2107322 2107588 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2107322..2107588 Brucella suis 1330 1167888 NP_699208.1 CDS repC NC_004311.2 155 1348 D identified by match to PFAM protein family HMM PF03428; replication initiation protein RepC 155..1348 Brucella suis 1330 1164437 NP_699209.1 CDS BRA0002 NC_004311.2 1413 1562 R hypothetical protein complement(1413..1562) Brucella suis 1330 1164438 NP_699210.1 CDS BRA0003 NC_004311.2 1551 1814 D hypothetical protein 1551..1814 Brucella suis 1330 1164439 NP_699211.1 CDS BRA0004 NC_004311.2 1963 2076 D hypothetical protein 1963..2076 Brucella suis 1330 1164440 NP_699212.1 CDS BRA0005 NC_004311.2 2092 3033 D similar to GB:M77016, SP:P28289, PID:339948, GB:M77016, SP:P28289, and PID:339948; identified by sequence similarity; ribokinase 2092..3033 Brucella suis 1330 1164441 NP_699213.1 CDS iunH NC_004311.2 3110 4108 R identified by match to PFAM protein family HMM PF01156; inosine-uridine preferring nucleoside hydrolase complement(3110..4108) Brucella suis 1330 1164442 NP_699214.1 CDS BRA0007 NC_004311.2 4131 5042 R identified by match to TIGR protein family HMM TIGR00023; ABC transporter permease complement(4131..5042) Brucella suis 1330 1164443 NP_699215.1 CDS BRA0008 NC_004311.2 5039 6118 R similar to GP:13022200, and GP:17134506; identified by sequence similarity; ABC transporter permease complement(5039..6118) Brucella suis 1330 1164444 NP_699216.1 CDS BRA0009 NC_004311.2 6180 7751 R similar to GP:13162075, GB:X52974, SP:P40598, and PID:48736; identified by sequence similarity; ABC transporter ATP-binding protein complement(6180..7751) Brucella suis 1330 1164445 NP_699217.1 CDS BRA0010 NC_004311.2 7754 8860 R similar to GP:11065692; identified by sequence similarity; Bmp family lipoprotein complement(7754..8860) Brucella suis 1330 1164446 NP_699218.1 CDS BRA0011 NC_004311.2 9104 9712 D similar to GP:15141208, and GP:15141208; identified by sequence similarity; hypothetical protein 9104..9712 Brucella suis 1330 1164447 NP_699219.1 CDS BRA0012 NC_004311.2 9684 10316 R similar to GP:15158815, and GP:6018425; identified by sequence similarity; enterobactin synthetase subunit D complement(9684..10316) Brucella suis 1330 1164448 NP_699220.1 CDS entA NC_004311.2 10399 11175 R catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydroxybenzoate-2,3-dehydrogenase complement(10399..11175) Brucella suis 1330 1164449 NP_699221.1 CDS entB NC_004311.2 11175 12047 R identified by match to PFAM protein family HMM PF00550; isochorismatase complement(11175..12047) Brucella suis 1330 1164450 NP_699222.1 CDS entE NC_004311.2 12099 13718 R bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate; enterobactin synthase subunit E complement(12099..13718) Brucella suis 1330 1164451 NP_699223.1 CDS entC NC_004311.2 13825 15000 R synthesizes isochorismate acid from chorismate; isochorismate synthase complement(13825..15000) Brucella suis 1330 1164452 NP_699224.1 CDS BRA0017 NC_004311.2 15072 16481 D similar to GP:13959028, and GP:1778502; identified by sequence similarity; enterobactin synthetase subunit F 15072..16481 Brucella suis 1330 1164453 NP_699225.1 CDS BRA0018 NC_004311.2 16529 17317 R identified by match to PFAM protein family HMM PF00174; molybdopterin-binding oxidoreductase complement(16529..17317) Brucella suis 1330 1164454 NP_699226.1 CDS BRA0019 NC_004311.2 17314 18123 R identified by match to PFAM protein family HMM PF01292; HupC/HyaC/HydC family protein complement(17314..18123) Brucella suis 1330 1164455 NP_699227.1 CDS BRA0020 NC_004311.2 18184 18423 R similar to GP:15157425, and GP:15157425; identified by sequence similarity; hypothetical protein complement(18184..18423) Brucella suis 1330 1164456 NP_699228.1 CDS BRA0021 NC_004311.2 18608 19132 D similar to GP:15157424; identified by sequence similarity; ECF subfamily RNA polymerase sigma factor 18608..19132 Brucella suis 1330 1164457 NP_699229.1 CDS BRA0022 NC_004311.2 19122 19757 D similar to GP:15157423, and GP:15157423; identified by sequence similarity; hypothetical protein 19122..19757 Brucella suis 1330 1164458 NP_699230.1 CDS BRA0023 NC_004311.2 19803 20543 R similar to GP:14523197; identified by sequence similarity; GntR family transcriptional regulator complement(19803..20543) Brucella suis 1330 1164459 NP_699231.1 CDS BRA0024 NC_004311.2 20661 22076 D similar to GB:Z11566, GB:J04991, GB:X53305, GB:M31303, GB:D28428, GB:X94912, SP:P16949, PID:1246757, PID:189388, PID:189426, PID:35595, and PID:57870; identified by sequence similarity; branched chain amino acid ABC transporter periplasmic amino acid-binding protein 20661..22076 Brucella suis 1330 1164460 NP_699232.1 CDS BRA0025 NC_004311.2 22118 23107 D similar to GP:15076000; identified by sequence similarity; branched-chain amino acid ABC transporter permease 22118..23107 Brucella suis 1330 1164461 NP_699233.1 CDS BRA0026 NC_004311.2 23111 24331 D similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; branched-chain amino acid ABC transporter permease 23111..24331 Brucella suis 1330 1164462 NP_699234.1 CDS BRA0027 NC_004311.2 24331 25083 D similar to GP:15159144; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 24331..25083 Brucella suis 1330 1164463 NP_699235.1 CDS BRA0028 NC_004311.2 25083 25799 D similar to GB:M93015, SP:P29916, and PID:150623; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 25083..25799 Brucella suis 1330 1164464 NP_699236.1 CDS BRA0029 NC_004311.2 25851 26333 D identified by match to PFAM protein family HMM PF00903; glyoxalase 25851..26333 Brucella suis 1330 1164465 NP_699237.1 CDS BRA0030 NC_004311.2 26337 27074 D similar to GB:L13289, SP:P47721, PID:551904, GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; 3-oxoacyl-ACP reductase 26337..27074 Brucella suis 1330 1164466 NP_699238.1 CDS BRA0031 NC_004311.2 27092 27844 D identified by match to TIGR protein family HMM TIGR01500; short chain dehydrogenase/reductase oxidoreductase 27092..27844 Brucella suis 1330 1164467 NP_699239.1 CDS BRA0032 NC_004311.2 27954 30143 D similar to SP:P27746, GB:X52592, and PID:46994; identified by sequence similarity; acetoin dehydrogenase, alpha/subunit beta 27954..30143 Brucella suis 1330 1164468 NP_699240.1 CDS BRA0033 NC_004311.2 30162 31427 D identified by match to TIGR protein family HMM TIGR01348; branched-chain alpha-keto acid dehydrogenase subunit E2 30162..31427 Brucella suis 1330 1164469 NP_699241.1 CDS BRA0034 NC_004311.2 31528 32313 D identified by match to TIGR protein family HMM TIGR00507; shikimate dehydrogenase 31528..32313 Brucella suis 1330 1164470 NP_699242.1 CDS BRA0035 NC_004311.2 32593 32886 D hypothetical protein 32593..32886 Brucella suis 1330 1164471 NP_699243.1 CDS BRA0036 NC_004311.2 32840 33121 R hypothetical protein complement(32840..33121) Brucella suis 1330 1164472 NP_699244.1 CDS BRA0037 NC_004311.2 33239 35956 D similar to GP:397973; identified by sequence similarity; magnesium ion-transporting ATPase E1-E2 family protein 33239..35956 Brucella suis 1330 1164473 NP_699245.1 CDS BRA0038 NC_004311.2 36041 36391 D hypothetical protein 36041..36391 Brucella suis 1330 1164474 NP_699246.1 CDS BRA0039 NC_004311.2 36522 36725 D hypothetical protein 36522..36725 Brucella suis 1330 1164475 NP_699247.1 CDS BRA0040 NC_004311.2 36727 37443 D similar to GB:L33799, and PID:642908; identified by sequence similarity; MgtC family protein 36727..37443 Brucella suis 1330 1164476 NP_699248.1 CDS BRA0041 NC_004311.2 37518 38588 D similar to GB:M57423, SP:P09329, SP:P11908, SP:P21108, PID:190522, and PID:2160401; identified by sequence similarity; sensor histidine kinase 37518..38588 Brucella suis 1330 1164477 NP_699249.1 CDS BRA0042 NC_004311.2 38585 39223 D similar to GB:L22075, SP:Q14344, and PID:404722; identified by sequence similarity; LuxR family transcriptional regulator 38585..39223 Brucella suis 1330 1164478 NP_699250.1 CDS BRA0043 NC_004311.2 39609 39971 R identified by match to PFAM protein family HMM PF00072; response regulator complement(39609..39971) Brucella suis 1330 1164480 NP_699251.1 CDS BRA0044 NC_004311.2 40290 41180 D formiminoglutamase 40290..41180 Brucella suis 1330 1164481 NP_699252.1 CDS BRA0045 NC_004311.2 41342 42118 D identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase 41342..42118 Brucella suis 1330 1164482 NP_699253.1 CDS BRA0046 NC_004311.2 42169 43164 R similar to GB:X15949, SP:P14316, and PID:33967; identified by sequence similarity; lysophospholipase L2 complement(42169..43164) Brucella suis 1330 1164483 NP_699254.1 CDS BRA0047 NC_004311.2 43204 43419 R hypothetical protein complement(43204..43419) Brucella suis 1330 1164484 NP_699255.1 CDS BRA0048 NC_004311.2 43514 43912 R hypothetical protein complement(43514..43912) Brucella suis 1330 1164485 NP_699256.1 CDS BRA0049 NC_004311.2 43964 44173 D hypothetical protein 43964..44173 Brucella suis 1330 1164486 NP_699257.1 CDS BRA0050 NC_004311.2 44146 44397 D hypothetical protein 44146..44397 Brucella suis 1330 1164487 NP_699258.1 CDS ibpA NC_004311.2 44476 44946 D similar to GB:X01703, GB:K00557, SP:P04687, SP:P05215, PID:340019, PID:340021, and PID:37492; identified by sequence similarity; 16 kDa heat shock protein A 44476..44946 Brucella suis 1330 1164488 NP_699259.1 CDS BRA0052 NC_004311.2 45084 46133 R threonine aldolase complement(45084..46133) Brucella suis 1330 1164489 NP_699260.1 CDS BRA0053 NC_004311.2 46402 46686 R hypothetical protein complement(46402..46686) Brucella suis 1330 1164490 NP_699261.1 CDS gltB NC_004311.2 46776 51527 D similar to SP:P04993, GB:X04581, GB:X04582, PID:42683, PID:42691, PID:882711, GB:U00096, and PID:1789182; identified by sequence similarity; glutamate synthase, large subunit 46776..51527 Brucella suis 1330 1164491 NP_699262.1 CDS gltD NC_004311.2 51609 53063 D glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase subunit beta 51609..53063 Brucella suis 1330 1164492 NP_699263.1 CDS BRA0056 NC_004311.2 53108 54511 R similar to SP:O06005, GB:M86808, SP:P29803, and PID:190790; identified by sequence similarity; amino acid permease complement(53108..54511) Brucella suis 1330 1164493 NP_699264.1 CDS BRA0057 NC_004311.2 54733 55884 R similar to GP:15075833; identified by sequence similarity; hypothetical protein complement(54733..55884) Brucella suis 1330 1164494 NP_699265.1 CDS BRA0058 NC_004311.2 56135 56653 R identified by match to PFAM protein family HMM PF00691; lipoprotein complement(56135..56653) Brucella suis 1330 1164495 NP_699266.1 CDS BRA0059 NC_004311.2 56802 57887 R similar to GP:5929876, and GP:8163894; identified by sequence similarity; type IV secretion system protein VirB11 complement(56802..57887) Brucella suis 1330 1164496 NP_699267.1 CDS BRA0060 NC_004311.2 57868 59043 R similar to GP:5929875, and GP:5929875; identified by sequence similarity; type IV secretion system protein VirB10 complement(57868..59043) Brucella suis 1330 1164497 NP_699268.1 CDS BRA0061 NC_004311.2 59040 59909 R similar to GP:5929874, and GP:5929874; identified by sequence similarity; type IV secretion system protein VirB9 complement(59040..59909) Brucella suis 1330 1164498 NP_699269.1 CDS BRA0062 NC_004311.2 59906 60625 R similar to GP:5929873, and GP:5929873; identified by sequence similarity; type IV secretion system protein VirB8 complement(59906..60625) Brucella suis 1330 1164499 NP_699270.1 CDS BRA0063 NC_004311.2 60628 60801 R similar to GP:5929872; identified by sequence similarity; type IV secretion system protein VirB7 complement(60628..60801) Brucella suis 1330 1164500 NP_699271.1 CDS BRA0064 NC_004311.2 60965 62008 R similar to GP:8163889, and GP:8163889; identified by sequence similarity; type IV secretion system protein VirB6 complement(60965..62008) Brucella suis 1330 1164501 NP_699272.1 CDS BRA0065 NC_004311.2 62192 62908 R similar to GP:5929870, and GP:5929870; identified by sequence similarity; type IV secretion system protein VirB5 complement(62192..62908) Brucella suis 1330 1164502 NP_699273.1 CDS BRA0066 NC_004311.2 62913 65408 R similar to GP:8163887, and GP:8163887; identified by sequence similarity; type IV secretion system protein VirB4 complement(62913..65408) Brucella suis 1330 1164503 NP_699274.1 CDS BRA0067 NC_004311.2 65408 65758 R similar to GP:5929868, and GP:5929868; identified by sequence similarity; type IV secretion system protein VirB3 complement(65408..65758) Brucella suis 1330 1164504 NP_699275.1 CDS BRA0068 NC_004311.2 65772 66089 R similar to GP:5929867, and GP:5929867; identified by sequence similarity; type IV secretion system protein VirB2 complement(65772..66089) Brucella suis 1330 1164505 NP_699276.1 CDS BRA0069 NC_004311.2 66525 67241 R similar to GP:5929866, and GP:5929866; identified by sequence similarity; type IV secretion system protein VirB1 complement(66525..67241) Brucella suis 1330 1164506 NP_699277.1 CDS BRA0070 NC_004311.2 67745 68971 R identified by match to PFAM protein family HMM PF01471; transglycosylase complement(67745..68971) Brucella suis 1330 1164507 NP_699278.1 CDS galU NC_004311.2 69383 70276 D identified by match to TIGR protein family HMM TIGR01208; UTP-glucose-1-phosphate uridylyltransferase 69383..70276 Brucella suis 1330 1164508 NP_699279.1 CDS BRA0072 NC_004311.2 70329 71867 R similar to GP:14023404; identified by sequence similarity; hypothetical protein complement(70329..71867) Brucella suis 1330 1164509 NP_699280.1 CDS BRA0073 NC_004311.2 72008 73009 D similar to GP:15159530; identified by sequence similarity; sugar isomerase KpsF/GutQ 72008..73009 Brucella suis 1330 1164510 NP_699281.1 CDS BRA0074 NC_004311.2 73148 73615 R hypothetical protein complement(73148..73615) Brucella suis 1330 1164511 NP_699282.1 CDS BRA0075 NC_004311.2 73636 74622 R similar to GP:15159532; identified by sequence similarity; SPFH domain-containing protein/band 7 family protein complement(73636..74622) Brucella suis 1330 1164512 NP_699283.1 CDS hemH NC_004311.2 74755 75813 R protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase complement(74755..75813) Brucella suis 1330 1164513 NP_699284.1 CDS omp10 NC_004311.2 75951 76331 R similar to GP:13877130, and GP:13877130; identified by sequence similarity; lipoprotein Omp10 complement(75951..76331) Brucella suis 1330 1164514 NP_699285.1 CDS BRA0078 NC_004311.2 76473 77918 R similar to GP:2276407; identified by sequence similarity; homospermidine synthase complement(76473..77918) Brucella suis 1330 1164515 NP_699286.1 CDS BRA0079 NC_004311.2 78030 78710 R similar to GP:14023390, and GP:14023390; identified by sequence similarity; hypothetical protein complement(78030..78710) Brucella suis 1330 1164516 NP_699287.1 CDS BRA0080 NC_004311.2 78644 79813 R catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine; aminodeoxychorismate synthase complement(78644..79813) Brucella suis 1330 1164517 NP_699288.1 CDS pepF NC_004311.2 79823 81685 R identified by match to PFAM protein family HMM PF01432; oligoendopeptidase F complement(79823..81685) Brucella suis 1330 1164518 NP_699289.1 CDS BRA0082 NC_004311.2 82033 83523 D similar to GP:15159542; identified by sequence similarity; Fis family transcriptional regulator 82033..83523 Brucella suis 1330 1164519 NP_699290.1 CDS BRA0083 NC_004311.2 83864 85777 D similar to GP:14023385; identified by sequence similarity; hypothetical protein 83864..85777 Brucella suis 1330 1164520 NP_699291.1 CDS BRA0086 NC_004311.2 87371 88297 D identified by match to PFAM protein family HMM PF00581; rhodanese family protein 87371..88297 Brucella suis 1330 1164523 NP_699292.1 CDS BRA0087 NC_004311.2 88332 88538 D hypothetical protein 88332..88538 Brucella suis 1330 1164524 NP_699293.1 CDS modA NC_004311.2 88578 89333 D similar to GP:15157753; identified by sequence similarity; molybdenum ABC transporter periplasmic molybdenum-binding protein 88578..89333 Brucella suis 1330 1164525 NP_699294.1 CDS modB NC_004311.2 89344 90030 D part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE; molybdate ABC transporter permease 89344..90030 Brucella suis 1330 1164526 NP_699295.1 CDS modC NC_004311.2 90027 91106 D similar to SP:P09833; identified by sequence similarity; molybdenum ABC transporter ATP-binding protein 90027..91106 Brucella suis 1330 1164527 NP_699296.1 CDS BRA0091 NC_004311.2 91176 91853 D identified by match to PFAM protein family HMM PF00583; acetyltransferase 91176..91853 Brucella suis 1330 1164528 NP_699297.1 CDS BRA0092 NC_004311.2 91840 92049 D hypothetical protein 91840..92049 Brucella suis 1330 1164529 NP_699298.1 CDS BRA0094 NC_004311.2 92101 92454 R hypothetical protein complement(92101..92454) Brucella suis 1330 1164530 NP_699300.1 CDS BRA0095 NC_004311.2 92511 92852 R identified by match to TIGR protein family HMM TIGR01598; hypothetical protein complement(92511..92852) Brucella suis 1330 1164532 NP_699301.1 CDS BRA0096 NC_004311.2 92994 94097 R identified by match to PFAM protein family HMM PF03741; hypothetical protein complement(92994..94097) Brucella suis 1330 1164533 NP_699302.1 CDS BRA0097 NC_004311.2 94097 94801 R similar to GP:15158721; identified by sequence similarity; hypothetical protein complement(94097..94801) Brucella suis 1330 1164534 NP_699303.1 CDS BRA0098 NC_004311.2 94841 95734 R identified by match to PFAM protein family HMM PF02492; LysR family transcriptional regulator complement(94841..95734) Brucella suis 1330 1164535 NP_699304.1 CDS BRA0099 NC_004311.2 95738 96943 R catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase complement(95738..96943) Brucella suis 1330 1164536 NP_699305.1 CDS BRA0100 NC_004311.2 97528 98661 D similar to SP:O50657; identified by sequence similarity; ornithine/DAP/arginine decarboxylase decarboxylase 2 97528..98661 Brucella suis 1330 1164537 NP_699306.1 CDS BRA0101 NC_004311.2 98737 100455 R similar to GP:15141223; identified by sequence similarity; polysaccharide accessory transport protein complement(98737..100455) Brucella suis 1330 1164538 NP_699307.1 CDS BRA0102 NC_004311.2 100472 100609 R hypothetical protein complement(100472..100609) Brucella suis 1330 1164539 NP_699308.1 CDS BRA0103 NC_004311.2 100581 101483 R similar to GP:14026189; identified by sequence similarity; hypothetical protein complement(100581..101483) Brucella suis 1330 1164540 NP_699309.1 CDS BRA0104 NC_004311.2 101441 102202 R identified by match to PFAM protein family HMM PF03808; WecB/TagA/CpsF family glycosyl transferase complement(101441..102202) Brucella suis 1330 1164541 NP_699310.1 CDS BRA0105 NC_004311.2 102203 103357 R hypothetical protein complement(102203..103357) Brucella suis 1330 1164542 NP_699311.1 CDS BRA0106 NC_004311.2 103351 103479 D hypothetical protein 103351..103479 Brucella suis 1330 1164543 NP_699312.1 CDS BRA0107 NC_004311.2 103529 104521 D identified by match to PFAM protein family HMM PF00535; glycosyl transferase group 2 family protein 103529..104521 Brucella suis 1330 1164544 NP_699313.1 CDS BRA0108 NC_004311.2 104490 105815 D exopolysaccharide production protein 104490..105815 Brucella suis 1330 1164545 NP_699314.1 CDS BRA0109 NC_004311.2 105829 106965 D similar to GP:15076091; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 105829..106965 Brucella suis 1330 1164546 NP_699315.1 CDS BRA0110 NC_004311.2 106962 108011 R similar to GP:6469270; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase complement(106962..108011) Brucella suis 1330 1164547 NP_699316.1 CDS gnd NC_004311.2 108328 109737 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 108328..109737 Brucella suis 1330 1164548 NP_699317.1 CDS BRA0112 NC_004311.2 109833 110894 R similar to GP:15157291; identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein complement(109833..110894) Brucella suis 1330 1164549 NP_699318.1 CDS BRA0113 NC_004311.2 110900 111718 R similar to GP:15075242, and GP:17740614; identified by sequence similarity; spermidine/putrescine ABC transporter permease complement(110900..111718) Brucella suis 1330 1164550 NP_699319.1 CDS BRA0114 NC_004311.2 111724 112608 R similar to GP:15075241, and GP:17740613; identified by sequence similarity; spermidine/putrescine ABC transporter permease complement(111724..112608) Brucella suis 1330 1164551 NP_699320.1 CDS BRA0115 NC_004311.2 112817 113920 R similar to GP:15075240; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein complement(112817..113920) Brucella suis 1330 1164552 NP_699321.1 CDS BRA0116 NC_004311.2 114329 115918 R identified by match to PFAM protein family HMM PF04039; Bcr/CflA subfamily drug resistance transporter complement(114329..115918) Brucella suis 1330 1164553 NP_699322.1 CDS BRA0118 NC_004311.2 117353 118096 D identified by match to PFAM protein family HMM PF00440; TetR family transcriptional regulator 117353..118096 Brucella suis 1330 1164555 NP_699323.1 CDS BRA0119 NC_004311.2 118370 119149 D similar to GP:9622950; identified by sequence similarity; LuxR family transcriptional regulator 118370..119149 Brucella suis 1330 1164556 NP_699324.1 CDS BRA0120 NC_004311.2 119218 119637 R similar to GP:15073579, and GP:15073579; identified by sequence similarity; hypothetical protein complement(119218..119637) Brucella suis 1330 1164557 NP_699325.1 CDS flhB NC_004311.2 119757 120827 R membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB complement(119757..120827) Brucella suis 1330 1164558 NP_699326.1 CDS BRA0123 NC_004311.2 121916 122236 R identified by match to PFAM protein family HMM PF01052; flagellar motor switch protein FliN complement(121916..122236) Brucella suis 1330 1164560 NP_699327.1 CDS BRA0124 NC_004311.2 122260 122721 R hypothetical protein complement(122260..122721) Brucella suis 1330 1164561 NP_699328.1 CDS BRA0125 NC_004311.2 122702 123652 R similar to SP:O54246; identified by sequence similarity; flagellar motor switch protein FliM complement(122702..123652) Brucella suis 1330 1164562 NP_699329.1 CDS motA NC_004311.2 123654 124526 R With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotA complement(123654..124526) Brucella suis 1330 1164563 NP_699330.1 CDS BRA0127 NC_004311.2 124684 125460 D similar to GP:15155497, and GP:15073585; identified by sequence similarity; hypothetical protein 124684..125460 Brucella suis 1330 1164564 NP_699331.1 CDS flgF NC_004311.2 125460 126191 D FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod protein FlgF 125460..126191 Brucella suis 1330 1164565 NP_699332.1 CDS fliI NC_004311.2 126188 127456 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 126188..127456 Brucella suis 1330 1164566 NP_699333.1 CDS BRA0130 NC_004311.2 127540 128058 D similar to GP:2916792, and GP:2459710; identified by sequence similarity; hypothetical protein 127540..128058 Brucella suis 1330 1164567 NP_699334.1 CDS BRA0131 NC_004311.2 128083 129060 R identified by match to PFAM protein family HMM PF01569; PAP2 family protein complement(128083..129060) Brucella suis 1330 1164568 NP_699335.1 CDS BRA0132 NC_004311.2 129048 129203 D hypothetical protein 129048..129203 Brucella suis 1330 1164569 NP_699336.1 CDS BRA0133 NC_004311.2 129358 129576 R hypothetical protein complement(129358..129576) Brucella suis 1330 1164570 NP_699337.1 CDS BRA0134 NC_004311.2 129604 129999 D identified by match to PFAM protein family HMM PF03751; hypothetical protein 129604..129999 Brucella suis 1330 1164571 NP_699338.1 CDS BRA0135 NC_004311.2 129996 130976 D similar to GB:Z17227, SP:Q08334, PID:393379, and PID:571296; identified by sequence similarity; glycosyl transferase group 2 family protein 129996..130976 Brucella suis 1330 1164572 NP_699339.1 CDS BRA0136 NC_004311.2 130960 131709 D identified by match to PFAM protein family HMM PF03633; hypothetical protein 130960..131709 Brucella suis 1330 1164573 NP_699340.1 CDS BRA0137 NC_004311.2 131706 133142 D similar to GP:4433524; identified by sequence similarity; dolichyl-phosphate-mannose-protein mannosyltransferase 131706..133142 Brucella suis 1330 1164574 NP_699341.1 CDS BRA0138 NC_004311.2 133264 133386 R hypothetical protein complement(133264..133386) Brucella suis 1330 1164575 NP_699342.1 CDS BRA0139 NC_004311.2 133385 134341 D similar to GP:15159134; identified by sequence similarity; AraC family transcriptional regulator 133385..134341 Brucella suis 1330 1164576 NP_699343.1 CDS BRA0140 NC_004311.2 134603 134707 D hypothetical protein 134603..134707 Brucella suis 1330 1164577 NP_699344.1 CDS BRA0141 NC_004311.2 134697 135134 D identified by match to PFAM protein family HMM PF01527; SyrB family protein 134697..135134 Brucella suis 1330 1164578 NP_699345.1 CDS BRA0142 NC_004311.2 135156 135266 D hypothetical protein 135156..135266 Brucella suis 1330 1164579 NP_699346.1 CDS BRA0143 NC_004311.2 135328 136629 R similar to GP:5281442, GB:U12431, SP:P26378, PID:521144, and PID:905387; identified by sequence similarity; phthalate transporter complement(135328..136629) Brucella suis 1330 1164580 NP_699347.1 CDS BRA0144 NC_004311.2 136655 137287 R identified by match to TIGR protein family HMM TIGR00760; aldolase complement(136655..137287) Brucella suis 1330 1164581 NP_699348.1 CDS BRA0145 NC_004311.2 137313 138278 R similar to GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, PID:825718, GB:M31651, GB:M27542, GB:X16351, GB:X05403, GB:X05792, GB:X16349, GB:X16350, SP:P04278, SP:P14689, PID:1335305, PID:36452, and PID:825718; identified by sequence similarity; hypothetical protein complement(137313..138278) Brucella suis 1330 1164582 NP_699349.1 CDS BRA0146 NC_004311.2 138278 139069 R similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; DeoR family transcriptional regulator complement(138278..139069) Brucella suis 1330 1164583 NP_699350.1 CDS BRA0147 NC_004311.2 139066 139851 R similar to GP:10197687, GB:J03799, GB:X15005, GB:S37431, GB:M14199, GB:X61156, GB:U36484, SP:P08865, PID:1125065, PID:34272, and PID:386857; identified by sequence similarity; hydroxypyruvate isomerase complement(139066..139851) Brucella suis 1330 1164584 NP_699351.1 CDS BRA0148 NC_004311.2 139851 141125 R similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; hypothetical protein complement(139851..141125) Brucella suis 1330 1164585 NP_699352.1 CDS BRA0150 NC_004311.2 142185 142322 D hypothetical protein 142185..142322 Brucella suis 1330 1164587 NP_699353.1 CDS flgB NC_004311.2 142399 142779 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Bradyrhizobium have one thick flagellum and several thin flagella; the proteins in this cluster are associated with the thin flagella; flagellar basal-body rod protein FlgB 142399..142779 Brucella suis 1330 1164588 NP_699354.1 CDS flgC NC_004311.2 142782 143204 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgC 142782..143204 Brucella suis 1330 1164589 NP_699355.1 CDS fliE NC_004311.2 143204 143539 D forms a junction between the M-ring and FlgB during flagella biosynthesis; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar hook-basal body protein FliE 143204..143539 Brucella suis 1330 1164590 NP_699356.1 CDS flgG NC_004311.2 143625 144413 D makes up the distal portion of the flagellar basal body rod; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thick flagella; flagellar basal body rod protein FlgG 143625..144413 Brucella suis 1330 1164591 NP_699357.1 CDS flgA NC_004311.2 144425 144907 D required for the assembly of the flagellar basal body P-ring; Bradyrhizobium japonicum has two types of flagella, a single thick flagella and a few thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body P-ring biosynthesis protein FlgA 144425..144907 Brucella suis 1330 1164592 NP_699358.2 CDS flgI NC_004311.2 145204 146277 D part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 145204..146277 Brucella suis 1330 1164593 NP_699359.1 CDS BRA0157 NC_004311.2 146274 146846 D similar to GP:12057224; identified by sequence similarity; hypothetical protein 146274..146846 Brucella suis 1330 1164594 NP_699360.1 CDS flgH NC_004311.2 146843 147559 D part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 146843..147559 Brucella suis 1330 1164595 NP_699361.1 CDS BRA0159 NC_004311.2 147572 148063 D similar to GP:15073597, GB:X56253, GB:X56254, GB:X56255, GB:X56256, GB:X56257, GB:M16985, SP:P20645, PID:307147, and PID:825692; identified by sequence similarity; flagellar protein FliL 147572..148063 Brucella suis 1330 1164596 NP_699362.1 CDS fliP NC_004311.2 148060 148800 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliP 148060..148800 Brucella suis 1330 1164597 NP_699363.1 CDS BRA0161 NC_004311.2 148895 149389 D hypothetical protein 148895..149389 Brucella suis 1330 1164598 NP_699364.1 CDS BRA0162 NC_004311.2 149402 149818 D similar to GP:15130936; identified by sequence similarity; hypothetical protein 149402..149818 Brucella suis 1330 1164599 NP_699365.1 CDS BRA0163 NC_004311.2 150014 150898 R similar to GP:3419687; identified by sequence similarity; LysR family transcriptional regulator complement(150014..150898) Brucella suis 1330 1164600 NP_699366.1 CDS BRA0164 NC_004311.2 150950 151081 D hypothetical protein 150950..151081 Brucella suis 1330 1164601 NP_699367.1 CDS BRA0165 NC_004311.2 150981 151079 R hypothetical protein complement(150981..151079) Brucella suis 1330 1164602 NP_699368.1 CDS BRA0166 NC_004311.2 151078 152295 D identified by match to PFAM protein family HMM PF02515; CAIB/BAIF family protein 151078..152295 Brucella suis 1330 1164603 NP_699369.1 CDS BRA0167 NC_004311.2 152363 153199 D identified by match to PFAM protein family HMM PF01524; hypothetical protein 152363..153199 Brucella suis 1330 1164604 NP_699370.1 CDS BRA0168 NC_004311.2 153193 154017 D identified by match to PFAM protein family HMM PF03328; citrate lyase subunit beta 153193..154017 Brucella suis 1330 1164605 NP_699371.1 CDS BRA0169 NC_004311.2 154212 154397 R hypothetical protein complement(154212..154397) Brucella suis 1330 1164606 NP_699372.1 CDS BRA0170 NC_004311.2 154467 155045 D similar to GB:L25675, PID:409767, and SP:P53641; identified by sequence similarity; cytochrome b561 154467..155045 Brucella suis 1330 1164607 NP_699373.1 CDS BRA0171 NC_004311.2 155544 155888 D hypothetical protein 155544..155888 Brucella suis 1330 1164608 NP_699374.1 CDS BRA0172 NC_004311.2 155836 156243 D hypothetical protein 155836..156243 Brucella suis 1330 1164609 NP_699375.1 CDS BRA0173 NC_004311.2 156288 159629 D similar to GP:15162141, and GP:15162141; identified by sequence similarity; outer membrane autotransporter 156288..159629 Brucella suis 1330 1164610 NP_699376.1 CDS cycA NC_004311.2 159865 160260 D similar to GB:L11566, SP:Q07020, PID:337493, GB:L11566, SP:Q07020, and PID:337493; identified by sequence similarity; cytochrome c2 159865..160260 Brucella suis 1330 1164611 NP_699377.1 CDS BRA0175 NC_004311.2 160484 160723 R hypothetical protein complement(160484..160723) Brucella suis 1330 1164612 NP_699378.1 CDS BRA0176 NC_004311.2 161154 161291 D hypothetical protein 161154..161291 Brucella suis 1330 1164613 NP_699379.1 CDS BRA0177 NC_004311.2 161369 162181 R similar to GP:15073704; identified by sequence similarity; GntR family transcriptional regulator complement(161369..162181) Brucella suis 1330 1164614 NP_699380.1 CDS BRA0178 NC_004311.2 162303 163223 R similar to GP:15073706; identified by sequence similarity; LysR family transcriptional regulator complement(162303..163223) Brucella suis 1330 1164615 NP_699381.1 CDS BRA0179 NC_004311.2 163383 163502 R hypothetical protein complement(163383..163502) Brucella suis 1330 1164616 NP_699382.1 CDS glcD NC_004311.2 163574 165070 D similar to SP:P32718, PID:396419, GB:U00096, and PID:1790522; identified by sequence similarity; glycolate oxidase subunit GlcD 163574..165070 Brucella suis 1330 1164617 NP_699383.1 CDS glcE NC_004311.2 165086 166318 D similar to GP:14026515, and SP:P52073; identified by sequence similarity; glycolate oxidase subunit GlcE 165086..166318 Brucella suis 1330 1164618 NP_699384.1 CDS glcF NC_004311.2 166323 167624 D similar to SP:P52074; identified by sequence similarity; glycolate oxidase, iron-sulfur subunit 166323..167624 Brucella suis 1330 1164619 NP_699385.1 CDS BRA0183 NC_004311.2 167848 168675 R similar to GP:4007669; identified by sequence similarity; aldo/keto reductase complement(167848..168675) Brucella suis 1330 1164620 NP_699386.1 CDS BRA0184 NC_004311.2 168951 169685 R similar to GP:15155625, and GP:15073711; identified by sequence similarity; hypothetical protein complement(168951..169685) Brucella suis 1330 1164621 NP_699387.1 CDS tag NC_004311.2 169925 170581 D identified by match to TIGR protein family HMM TIGR00624; DNA-3-methyladenine glycosidase I 169925..170581 Brucella suis 1330 1164622 NP_699388.1 CDS BRA0186 NC_004311.2 170700 171317 D identified by match to TIGR protein family HMM TIGR00948; amino acid transporter LysE 170700..171317 Brucella suis 1330 1164623 NP_699389.1 CDS hisS NC_004311.2 171428 172936 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 171428..172936 Brucella suis 1330 1164624 NP_699390.1 CDS hisZ NC_004311.2 172945 174075 D May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase 172945..174075 Brucella suis 1330 1164625 NP_699391.1 CDS hisG NC_004311.2 174072 174767 D short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 174072..174767 Brucella suis 1330 1164626 NP_699392.1 CDS BRA0191 NC_004311.2 176364 176765 R hypothetical protein complement(176364..176765) Brucella suis 1330 1164628 NP_699393.1 CDS fumC NC_004311.2 176868 178259 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(176868..178259) Brucella suis 1330 1164629 NP_699394.1 CDS BRA0193 NC_004311.2 178409 178696 R hypothetical protein complement(178409..178696) Brucella suis 1330 1164630 NP_699395.1 CDS BRA0194 NC_004311.2 178993 179214 R hypothetical protein complement(178993..179214) Brucella suis 1330 1164631 NP_699396.1 CDS groEL NC_004311.2 179416 181056 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL complement(179416..181056) Brucella suis 1330 1164632 NP_699397.1 CDS groES NC_004311.2 181147 181443 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(181147..181443) Brucella suis 1330 1164633 NP_699398.1 CDS BRA0197 NC_004311.2 181563 181703 D hypothetical protein 181563..181703 Brucella suis 1330 1164634 NP_699399.1 CDS BRA0198 NC_004311.2 181756 181860 R hypothetical protein complement(181756..181860) Brucella suis 1330 1164635 NP_699400.1 CDS BRA0199 NC_004311.2 181921 182772 D identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 181921..182772 Brucella suis 1330 1164636 NP_699401.1 CDS BRA0200 NC_004311.2 182808 182921 D hypothetical protein 182808..182921 Brucella suis 1330 1164637 NP_699402.1 CDS ribF NC_004311.2 182902 183849 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase 182902..183849 Brucella suis 1330 1164638 NP_699403.1 CDS ileS NC_004311.2 184193 187111 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 184193..187111 Brucella suis 1330 1164639 NP_699404.1 CDS BRA0203 NC_004311.2 187303 187974 D similar to GP:15073729; identified by sequence similarity; hypothetical protein 187303..187974 Brucella suis 1330 1164640 NP_699405.1 CDS BRA0204 NC_004311.2 188319 188879 D similar to SP:P08732; identified by sequence similarity; cytochrome b561 188319..188879 Brucella suis 1330 1164641 NP_699406.1 CDS BRA0205 NC_004311.2 188933 189406 R similar to GP:15155649; identified by sequence similarity; cytidine and deoxycytidylate deaminase complement(188933..189406) Brucella suis 1330 1164642 YP_002519390.1 CDS BRA0206 NC_004311.2 189496 191292 D RNA pseudouridylate synthase 189496..191292 Brucella suis 1330 1164643 NP_699407.1 CDS BRA0207 NC_004311.2 191273 191836 D identified by match to PFAM protein family HMM PF03602; hypothetical protein 191273..191836 Brucella suis 1330 1164644 NP_699408.1 CDS BRA0209 NC_004311.2 194810 195691 D identified by match to PFAM protein family HMM PF01734; hypothetical protein 194810..195691 Brucella suis 1330 1164646 NP_699409.1 CDS BRA0210 NC_004311.2 195704 197611 R similar to GP:15073737; identified by sequence similarity; glutathione-regulated potassium-efflux system protein complement(195704..197611) Brucella suis 1330 1164647 NP_699410.1 CDS pmbA NC_004311.2 197750 199093 D similar to GB:V00566, GB:J00299, GB:M29386, GB:D00411, SP:P01236, GB:U75583, PID:1620399, PID:1658518, PID:190354, PID:190356, PID:220018, PID:34211, PID:531101, and PID:531103; identified by sequence similarity; pmbA protein 197750..199093 Brucella suis 1330 1164648 NP_699411.1 CDS BRA0212 NC_004311.2 199125 199889 D identified by match to TIGR protein family HMM TIGR01330; inositol monophosphatase 199125..199889 Brucella suis 1330 1164649 NP_699412.1 CDS BRA0213 NC_004311.2 199928 200179 D similar to GP:15155658, and GP:15073740; identified by sequence similarity; hypothetical protein 199928..200179 Brucella suis 1330 1164650 NP_699413.1 CDS BRA0214 NC_004311.2 200243 200986 D similar to GP:14027592; identified by sequence similarity; hypothetical protein 200243..200986 Brucella suis 1330 1164651 NP_699414.1 CDS kdtA NC_004311.2 200983 202323 D catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A; 3-deoxy-D-manno-octulosonic-acid transferase 200983..202323 Brucella suis 1330 1164652 NP_699415.1 CDS lpxK NC_004311.2 202326 203351 D transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate; tetraacyldisaccharide 4'-kinase 202326..203351 Brucella suis 1330 1164653 NP_699416.1 CDS BRA0217 NC_004311.2 203365 203601 R similar to GP:15073746; identified by sequence similarity; hypothetical protein complement(203365..203601) Brucella suis 1330 1164654 NP_699417.1 CDS mutL NC_004311.2 203699 205570 R This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein complement(203699..205570) Brucella suis 1330 1164655 NP_699418.1 CDS mucK NC_004311.2 205754 207037 R similar to GB:Z25795, SP:P39118, PID:397488, PID:2293136, GB:AL009126, GB:Z25795, SP:P39118, PID:397488, PID:2293136, and GB:AL009126; identified by sequence similarity; cis,cis-muconate transport protein MucK complement(205754..207037) Brucella suis 1330 1164656 NP_699419.1 CDS BRA0220 NC_004311.2 207135 208289 R similar to SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase complement(207135..208289) Brucella suis 1330 1164657 NP_699420.1 CDS BRA0221 NC_004311.2 208346 209200 R identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator complement(208346..209200) Brucella suis 1330 1164658 NP_699421.1 CDS BRA0222 NC_004311.2 209460 210221 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 209460..210221 Brucella suis 1330 1164659 NP_699422.1 CDS BRA0223 NC_004311.2 210226 211755 D converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase 210226..211755 Brucella suis 1330 1164660 NP_699423.1 CDS BRA0224 NC_004311.2 211978 213219 D similar to GP:14587414; identified by sequence similarity; CAIB/BAIF family protein 211978..213219 Brucella suis 1330 1164661 NP_699424.1 CDS BRA0226 NC_004311.2 214457 214921 D identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator 214457..214921 Brucella suis 1330 1164663 NP_699425.1 CDS BRA0227 NC_004311.2 214967 215674 R identified by match to TIGR protein family HMM TIGR01382; ThiJ/PfpI family protein complement(214967..215674) Brucella suis 1330 1164664 NP_699426.1 CDS BRA0228 NC_004311.2 215905 217245 R similar to GP:15159266; identified by sequence similarity; sensor histidine kinase complement(215905..217245) Brucella suis 1330 1164665 NP_699427.1 CDS BRA0230 NC_004311.2 218041 218205 R hypothetical protein complement(218041..218205) Brucella suis 1330 1164667 NP_699428.1 CDS BRA0231 NC_004311.2 218177 218449 D hypothetical protein 218177..218449 Brucella suis 1330 1164668 NP_699429.1 CDS BRA0232 NC_004311.2 218617 219087 D hypothetical protein 218617..219087 Brucella suis 1330 1164669 NP_699430.1 CDS BRA0233 NC_004311.2 219098 221302 D identified by match to PFAM protein family HMM PF03929; FAD-binding oxidoreductase 219098..221302 Brucella suis 1330 1164670 NP_699431.1 CDS BRA0234 NC_004311.2 221283 222260 D similar to SP:P41780; identified by sequence similarity; ApbE family protein 221283..222260 Brucella suis 1330 1164671 NP_699432.1 CDS BRA0235 NC_004311.2 222303 223478 R similar to GP:15073890; identified by sequence similarity; GAF/GGDEF domain-containing protein complement(222303..223478) Brucella suis 1330 1164672 NP_699433.1 CDS BRA0236 NC_004311.2 223761 224654 R similar to GP:15159282; identified by sequence similarity; hypothetical protein complement(223761..224654) Brucella suis 1330 1164673 NP_699434.1 CDS BRA0237 NC_004311.2 224630 224770 D hypothetical protein 224630..224770 Brucella suis 1330 1164674 NP_699435.1 CDS BRA0238 NC_004311.2 224894 225571 D similar to GP:15140120; identified by sequence similarity; GntR family transcriptional regulator 224894..225571 Brucella suis 1330 1164675 NP_699436.1 CDS BRA0239 NC_004311.2 225672 226634 D similar to GP:15140121; identified by sequence similarity; dihydrodipicolinate synthase 225672..226634 Brucella suis 1330 1164676 NP_699437.1 CDS BRA0240 NC_004311.2 226697 227734 R similar to GP:15140123; identified by sequence similarity; malate/L-lactate dehydrogenase complement(226697..227734) Brucella suis 1330 1164677 NP_699438.1 CDS BRA0241 NC_004311.2 227748 227849 R hypothetical protein complement(227748..227849) Brucella suis 1330 1164678 NP_699439.1 CDS BRA0242 NC_004311.2 227853 227951 R hypothetical protein complement(227853..227951) Brucella suis 1330 1164679 NP_699440.1 CDS BRA0243 NC_004311.2 227971 229239 D identified by match to PFAM protein family HMM PF03772; hypothetical protein 227971..229239 Brucella suis 1330 1164680 NP_699441.1 CDS BRA0244 NC_004311.2 229247 229720 R similar to GP:6978955; identified by sequence similarity; hypothetical protein complement(229247..229720) Brucella suis 1330 1164681 NP_699442.1 CDS BRA0245 NC_004311.2 229777 229932 R similar to GP:6978956, and GP:6978956; identified by sequence similarity; hypothetical protein complement(229777..229932) Brucella suis 1330 1164682 NP_699443.1 CDS BRA0246 NC_004311.2 230036 230605 D similar to GP:6978957; identified by sequence similarity; cytochrome c oxidase subunit III 230036..230605 Brucella suis 1330 1164683 NP_699444.1 CDS norF NC_004311.2 230613 230891 D similar to GP:6978958, and GP:6978958; identified by sequence similarity; norF protein 230613..230891 Brucella suis 1330 1164684 NP_699445.1 CDS norC NC_004311.2 231051 231503 D similar to GP:6978959, and SP:Q51662; identified by sequence similarity; nitric-oxide reductase, small subunit 231051..231503 Brucella suis 1330 1164685 NP_699446.1 CDS norB NC_004311.2 231529 232878 D similar to GP:6978960, and SP:P98008; identified by sequence similarity; nitric-oxide reductase, large subunit 231529..232878 Brucella suis 1330 1164686 NP_699447.1 CDS BRA0250 NC_004311.2 232969 233781 D similar to GP:6978961, GB:U10072, SP:P98177, and PID:501087; identified by sequence similarity; CbbQ/NirQ/NorQ/GpvN family protein 232969..233781 Brucella suis 1330 1164687 NP_699448.1 CDS norD NC_004311.2 233793 235694 D similar to GP:6978962, GB:K00396, GB:M10065, GB:M12529, GB:X00199, GB:Z70760, GB:X92000, SP:P02649, PID:1263123, PID:178849, PID:178851, PID:178853, PID:579590, and PID:929610; identified by sequence similarity; norD protein 233793..235694 Brucella suis 1330 1164688 NP_699449.1 CDS BRA0252 NC_004311.2 235874 236158 D similar to GP:14523804; identified by sequence similarity; hypothetical protein 235874..236158 Brucella suis 1330 1164689 NP_699450.1 CDS BRA0253 NC_004311.2 236194 237561 D similar to GP:14523803, and GP:14523803; identified by sequence similarity; hypothetical protein 236194..237561 Brucella suis 1330 1164690 NP_699451.1 CDS BRA0254 NC_004311.2 237558 238085 D similar to GP:14523802, and GP:14523802; identified by sequence similarity; hypothetical protein 237558..238085 Brucella suis 1330 1164691 NP_699452.1 CDS BRA0255 NC_004311.2 238092 238418 D similar to GP:14523801, and GP:14523801; identified by sequence similarity; hypothetical protein 238092..238418 Brucella suis 1330 1164692 NP_699453.1 CDS BRA0256 NC_004311.2 238542 239717 D similar to GP:15156967, and GP:15156967; identified by sequence similarity; hypothetical protein 238542..239717 Brucella suis 1330 1164693 NP_699454.1 CDS BRA0257 NC_004311.2 239714 240298 D similar to GP:15074522, and GP:15074522; identified by sequence similarity; hypothetical protein 239714..240298 Brucella suis 1330 1164694 NP_699455.1 CDS BRA0258 NC_004311.2 240249 240947 D identified by match to TIGR protein family HMM TIGR01409; hypothetical protein 240249..240947 Brucella suis 1330 1164695 NP_699456.1 CDS BRA0259 NC_004311.2 241023 241172 D hypothetical protein 241023..241172 Brucella suis 1330 1164696 NP_699457.1 CDS BRA0260 NC_004311.2 241303 242433 D similar to GB:J05016, SP:P13667, PID:181508, GB:J05016, SP:P13667, and PID:181508; identified by sequence similarity; copper-containing nitrite reductase 241303..242433 Brucella suis 1330 1164697 NP_699458.1 CDS BRA0261 NC_004311.2 242566 243486 D similar to GP:14523796, and GP:2773329; identified by sequence similarity; NirV protein 242566..243486 Brucella suis 1330 1164698 NP_699459.1 CDS BRA0262 NC_004311.2 243587 244282 D similar to GP:6978954; identified by sequence similarity; Crp/Fnr family transcriptional regulator 243587..244282 Brucella suis 1330 1164699 NP_699460.1 CDS BRA0263 NC_004311.2 244365 245420 D similar to GP:15140338; identified by sequence similarity; LacI family sugar-binding transcriptional regulator 244365..245420 Brucella suis 1330 1164700 NP_699461.1 CDS BRA0264 NC_004311.2 245601 245822 R hypothetical protein complement(245601..245822) Brucella suis 1330 1164701 NP_699462.1 CDS BRA0265 NC_004311.2 245821 246873 D similar to GP:2661681; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 245821..246873 Brucella suis 1330 1164702 NP_699463.1 CDS BRA0266 NC_004311.2 247178 248038 D similar to GP:2661682, and GP:12659326; identified by sequence similarity; sugar ABC transporter ATP-binding protein 247178..248038 Brucella suis 1330 1164703 NP_699464.1 CDS BRA0267 NC_004311.2 248035 249273 D similar to GP:2661683, and GP:2661683; identified by sequence similarity; sugar ABC transporter permease 248035..249273 Brucella suis 1330 1164704 NP_699465.1 CDS BRA0268 NC_004311.2 249560 250288 D similar to GP:11036625, GB:M57506, GB:M57502, SP:P22362, PID:184506, and PID:339729; identified by sequence similarity; ribitol dehydrogenase 249560..250288 Brucella suis 1330 1164705 NP_699466.1 CDS BRA0269 NC_004311.2 250301 251905 D similar to GP:15158921; identified by sequence similarity; ribitol kinase 250301..251905 Brucella suis 1330 1164706 NP_699467.1 CDS BRA0270 NC_004311.2 252037 252702 R similar to GP:15158337, and GP:15158337; identified by sequence similarity; hypothetical protein complement(252037..252702) Brucella suis 1330 1164707 NP_699468.1 CDS BRA0271 NC_004311.2 252699 253175 R similar to SP:P08500, GB:M18576, PID:551957, PID:581499, SP:P08500, GB:M18576, PID:551957, and PID:581499; identified by sequence similarity; hypothetical protein complement(252699..253175) Brucella suis 1330 1164708 NP_699469.1 CDS BRA0273 NC_004311.2 255470 255709 D hypothetical protein 255470..255709 Brucella suis 1330 1164710 NP_699470.1 CDS BRA0274 NC_004311.2 255722 258085 D similar to GP:14523755; identified by sequence similarity; transcriptional regulator NosR 255722..258085 Brucella suis 1330 1164711 NP_699471.1 CDS nosZ NC_004311.2 258106 260025 D reduces nitrous oxide to nitrogen; nitrous-oxide reductase 258106..260025 Brucella suis 1330 1164712 NP_699472.1 CDS nosD NC_004311.2 260031 261425 D similar to SP:P19843, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; copper ABC transporter periplasmic copper-binding protein 260031..261425 Brucella suis 1330 1164713 NP_699473.1 CDS nosF NC_004311.2 261463 262413 D similar to SP:P19844, GB:X04803, SP:P02248, PID:1304128, PID:1490419, PID:340058, PID:340068, and PID:825728; identified by sequence similarity; copper ABC transporter ATP-binding protein 261463..262413 Brucella suis 1330 1164714 NP_699474.1 CDS nosY NC_004311.2 262410 263240 D similar to GP:2177176, GB:L06175, and PID:189449; identified by sequence similarity; nitrous-oxide reductase subunit NosY 262410..263240 Brucella suis 1330 1164715 NP_699475.1 CDS BRA0279 NC_004311.2 263237 263776 D similar to GP:2177177; identified by sequence similarity; protein disulfide isomerase 263237..263776 Brucella suis 1330 1164716 NP_699476.1 CDS BRA0280 NC_004311.2 263788 264780 D similar to GP:14523761, and GP:2177178; identified by sequence similarity; nosX protein 263788..264780 Brucella suis 1330 1164717 NP_699477.1 CDS nnrR NC_004311.2 264895 265593 D similar to GP:15158856, GB:L06214, PID:153222, and PID:886941; identified by sequence similarity; transcriptional regulator NnrR 264895..265593 Brucella suis 1330 1164718 YP_002519391.1 CDS BRA0282 NC_004311.2 265731 266171 D pseudoazurin 265731..266171 Brucella suis 1330 1164719 NP_699478.1 CDS BRA0283 NC_004311.2 266222 267463 D similar to GP:15158853, and GP:14523798; identified by sequence similarity; hypothetical protein 266222..267463 Brucella suis 1330 1164720 NP_699479.1 CDS BRA0284 NC_004311.2 267537 268577 R ABC transporter periplasmic binding protein complement(267537..268577) Brucella suis 1330 1164721 NP_699480.1 CDS BRA0285 NC_004311.2 268603 269394 R similar to GP:15158995; identified by sequence similarity; ABC transporter permease complement(268603..269394) Brucella suis 1330 1164722 NP_699481.1 CDS BRA0286 NC_004311.2 269391 270236 R identified by match to TIGR protein family HMM TIGR00972; ABC transporter ATP binding protein complement(269391..270236) Brucella suis 1330 1164723 NP_699482.1 CDS BRA0287 NC_004311.2 270263 270565 D hypothetical protein 270263..270565 Brucella suis 1330 1164724 NP_699483.1 CDS BRA0288 NC_004311.2 270471 270614 R hypothetical protein complement(270471..270614) Brucella suis 1330 1164725 NP_699484.1 CDS BRA0289 NC_004311.2 270663 271595 R similar to GP:15158836; identified by sequence similarity; protease complement(270663..271595) Brucella suis 1330 1164726 NP_699485.1 CDS BRA0290 NC_004311.2 271598 272575 R similar to GP:15158837; identified by sequence similarity; U32 family peptidase complement(271598..272575) Brucella suis 1330 1164727 NP_699486.1 CDS BRA0291 NC_004311.2 272566 273090 R similar to GP:15158838, and GP:15158838; identified by sequence similarity; hypothetical protein complement(272566..273090) Brucella suis 1330 1164728 NP_699487.1 CDS ubiD NC_004311.2 273204 274718 D similar to GP:14523816; identified by sequence similarity; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 273204..274718 Brucella suis 1330 1164729 NP_699488.1 CDS BRA0293 NC_004311.2 274715 275305 D catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 274715..275305 Brucella suis 1330 1164730 NP_699489.1 CDS BRA0294 NC_004311.2 275315 275851 R hypothetical protein complement(275315..275851) Brucella suis 1330 1164731 NP_699490.1 CDS BRA0295 NC_004311.2 275848 276783 R peptidyl-prolyl cis-trans isomerase complement(275848..276783) Brucella suis 1330 1164732 NP_699491.1 CDS narI NC_004311.2 276789 277514 R similar to GB:M64929, SP:Q00005, SP:Q00007, and PID:190422; identified by sequence similarity; respiratory nitrate reductase subunit gamma complement(276789..277514) Brucella suis 1330 1164733 NP_699492.1 CDS narJ NC_004311.2 277525 278232 R similar to GP:11344603, GB:L08239, and PID:950412; identified by sequence similarity; respiratory nitrate reductase subunit delta complement(277525..278232) Brucella suis 1330 1164734 NP_699493.1 CDS narH NC_004311.2 278232 279770 R similar to GB:D90359, GB:M73442, GB:M73444, GB:X07024, SP:P21675, and PID:29733; identified by sequence similarity; respiratory nitrate reductase subunit beta complement(278232..279770) Brucella suis 1330 1164735 NP_699494.1 CDS narG NC_004311.2 279767 283531 R similar to SP:P09152; identified by sequence similarity; respiratory nitrate reductase subunit alpha complement(279767..283531) Brucella suis 1330 1164736 NP_699495.1 CDS narK NC_004311.2 283555 286242 R similar to GP:14348603; identified by sequence similarity; nitrite extrusion protein complement(283555..286242) Brucella suis 1330 1164737 NP_699496.1 CDS ftrB NC_004311.2 286532 287242 D upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism; transcriptional activator FtrB 286532..287242 Brucella suis 1330 1164738 NP_699497.1 CDS BRA0302 NC_004311.2 287297 288313 R similar to GP:5802909; identified by sequence similarity; sugar-binding protein complement(287297..288313) Brucella suis 1330 1164739 NP_699498.1 CDS BRA0303 NC_004311.2 288321 288437 R hypothetical protein complement(288321..288437) Brucella suis 1330 1164740 NP_699499.1 CDS BRA0304 NC_004311.2 288664 289929 D similar to GP:5802910, and GP:2828820; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 288664..289929 Brucella suis 1330 1164741 NP_699500.1 CDS BRA0305 NC_004311.2 290006 290983 D similar to GP:5802911, and GP:2828821; identified by sequence similarity; sugar ABC transporter permease 290006..290983 Brucella suis 1330 1164742 NP_699501.1 CDS BRA0306 NC_004311.2 290986 291813 D similar to GP:5802912, and GP:13517311; identified by sequence similarity; sugar ABC transporter permease 290986..291813 Brucella suis 1330 1164743 NP_699502.1 CDS BRA0307 NC_004311.2 291820 292821 D similar to GP:5802913; identified by sequence similarity; sugar ABC transporter ATP-binding protein 291820..292821 Brucella suis 1330 1164744 NP_699503.1 CDS BRA0308 NC_004311.2 292860 293669 D similar to GP:5802914; identified by sequence similarity; hypothetical protein 292860..293669 Brucella suis 1330 1164745 NP_699504.1 CDS BRA0309 NC_004311.2 293678 294724 D similar to GP:5802915; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 293678..294724 Brucella suis 1330 1164746 NP_699505.1 CDS BRA0310 NC_004311.2 294961 295458 D hypothetical protein 294961..295458 Brucella suis 1330 1164747 NP_699506.1 CDS BRA0311 NC_004311.2 295772 297400 D similar to GP:15073164, and GP:12055084; identified by sequence similarity; transporter 295772..297400 Brucella suis 1330 1164748 NP_699507.1 CDS BRA0312 NC_004311.2 297387 297503 D hypothetical protein 297387..297503 Brucella suis 1330 1164749 NP_699508.1 CDS BRA0313 NC_004311.2 297557 297883 R hypothetical protein complement(297557..297883) Brucella suis 1330 1164750 NP_699509.1 CDS nrdH NC_004311.2 298077 298298 D similar to GP:1800061; identified by sequence similarity; glutaredoxin-like protein nrdH 298077..298298 Brucella suis 1330 1164751 NP_699510.1 CDS nrdI NC_004311.2 298312 298719 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein 298312..298719 Brucella suis 1330 1164752 NP_699511.1 CDS nrdE NC_004311.2 298770 300911 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 298770..300911 Brucella suis 1330 1164753 NP_699512.1 CDS nrdF NC_004311.2 300926 301915 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 300926..301915 Brucella suis 1330 1164754 NP_699513.1 CDS BRA0318 NC_004311.2 302085 302309 R hypothetical protein complement(302085..302309) Brucella suis 1330 1164755 NP_699514.1 CDS BRA0319 NC_004311.2 302443 302535 D hypothetical protein 302443..302535 Brucella suis 1330 1164756 NP_699515.1 CDS BRA0320 NC_004311.2 302520 302651 D hypothetical protein 302520..302651 Brucella suis 1330 1164757 NP_699516.1 CDS minC NC_004311.2 302781 303542 D blocks the formation of polar Z-ring septums; septum formation inhibitor 302781..303542 Brucella suis 1330 1164758 NP_699517.1 CDS minD NC_004311.2 303570 304385 D similar to GP:15160138, and SP:P18197; identified by sequence similarity; septum site-determining protein MinD 303570..304385 Brucella suis 1330 1164759 NP_699518.1 CDS minE NC_004311.2 304382 304654 D works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 304382..304654 Brucella suis 1330 1164760 NP_699519.1 CDS BRA0324 NC_004311.2 304698 304865 D hypothetical protein 304698..304865 Brucella suis 1330 1164761 NP_699520.1 CDS BRA0325 NC_004311.2 305194 305586 R similar to GP:15159179, and GP:15159179; identified by sequence similarity; hypothetical protein complement(305194..305586) Brucella suis 1330 1164763 NP_699521.1 CDS BRA0326 NC_004311.2 305962 307008 D similar to GP:14524112, and GP:17428750; identified by sequence similarity; spermidine/putrescine ABC transporter periplasmic spermidine/putrescine-binding protein 305962..307008 Brucella suis 1330 1164764 NP_699522.1 CDS BRA0327 NC_004311.2 307082 308149 D similar to GP:14524111; identified by sequence similarity; spermidine/putrescine ABC transporter ATP-binding protein 307082..308149 Brucella suis 1330 1164765 NP_699523.1 CDS BRA0328 NC_004311.2 308083 309321 D similar to GP:14524110, and SP:P23860; identified by sequence similarity; spermidine/putrescine ABC transporter permease 308083..309321 Brucella suis 1330 1164766 NP_699524.1 CDS BRA0329 NC_004311.2 309324 310100 D similar to GP:14524109, GB:X59932, SP:P41240, PID:30256, and PID:30315; identified by sequence similarity; spermidine/putrescine ABC transporter permease 309324..310100 Brucella suis 1330 1164767 NP_699525.1 CDS BRA0330 NC_004311.2 310412 310591 D hypothetical protein 310412..310591 Brucella suis 1330 1164768 NP_699526.1 CDS BRA0331 NC_004311.2 310588 310812 D hypothetical protein 310588..310812 Brucella suis 1330 1164769 NP_699527.1 CDS BRA0332 NC_004311.2 311049 311576 D hypothetical protein 311049..311576 Brucella suis 1330 1164770 NP_699528.1 CDS BRA0333 NC_004311.2 311718 312218 R hypothetical protein complement(311718..312218) Brucella suis 1330 1164771 NP_699529.1 CDS BRA0334 NC_004311.2 312215 315439 R similar to GP:15141215; identified by sequence similarity; hydrophobe/amphiphile efflux-1 family protein complement(312215..315439) Brucella suis 1330 1164772 NP_699530.1 CDS BRA0335 NC_004311.2 315443 316678 R similar to GP:14524048; identified by sequence similarity; HlyD family secretion protein complement(315443..316678) Brucella suis 1330 1164773 NP_699531.1 CDS BRA0336 NC_004311.2 316864 317397 R hypothetical protein complement(316864..317397) Brucella suis 1330 1164774 NP_699532.1 CDS BRA0337 NC_004311.2 317472 317645 R hypothetical protein complement(317472..317645) Brucella suis 1330 1164775 NP_699533.1 CDS BRA0340 NC_004311.2 321132 322085 D catalyzes the formation of glutamate from glutamine; glutaminase 321132..322085 Brucella suis 1330 1164778 NP_699534.1 CDS hdeA NC_004311.2 322233 322577 D inactive form; acid-resistance protein 322233..322577 Brucella suis 1330 1164779 NP_699535.1 CDS BRA0342 NC_004311.2 322740 322838 D hypothetical protein 322740..322838 Brucella suis 1330 1164780 NP_699536.1 CDS BRA0343 NC_004311.2 323090 323341 D hypothetical protein 323090..323341 Brucella suis 1330 1164781 NP_699537.1 CDS BRA0344 NC_004311.2 323418 325010 R similar to SP:P77473; identified by sequence similarity; diguanylate phosphodiesterase complement(323418..325010) Brucella suis 1330 1164782 NP_699538.1 CDS BRA0345 NC_004311.2 325305 325571 R hypothetical protein complement(325305..325571) Brucella suis 1330 1164783 NP_699539.1 CDS BRA0346 NC_004311.2 325800 326687 D identified by match to PFAM protein family HMM PF03466; LysR family transcriptional regulator 325800..326687 Brucella suis 1330 1164784 NP_699540.1 CDS BRA0347 NC_004311.2 326808 328223 R similar to GP:3510759; identified by sequence similarity; mannose-1-phosphate guanylyltransferase complement(326808..328223) Brucella suis 1330 1164785 NP_699541.1 CDS BRA0348 NC_004311.2 328220 329653 R similar to GP:2738951, SP:P06187, GB:K03551, GB:X52093, PID:154137, and PID:47739; identified by sequence similarity; phosphoglucomutase complement(328220..329653) Brucella suis 1330 1164786 NP_699542.1 CDS BRA0349 NC_004311.2 329773 330879 R similar to GP:7799513, and GP:7799513; identified by sequence similarity; hypothetical protein complement(329773..330879) Brucella suis 1330 1164787 NP_699543.1 CDS BRA0350 NC_004311.2 330903 332258 R identified by match to PFAM protein family HMM PF03595; voltage gated chloride channel family protein complement(330903..332258) Brucella suis 1330 1164788 NP_699544.1 CDS BRA0351 NC_004311.2 332317 332478 R hypothetical protein complement(332317..332478) Brucella suis 1330 1164789 NP_699545.1 CDS guaB NC_004311.2 332453 333946 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase 332453..333946 Brucella suis 1330 1164790 NP_699546.1 CDS BRA0353 NC_004311.2 334151 335224 R similar to GP:15140396; identified by sequence similarity; cytochrome c family protein complement(334151..335224) Brucella suis 1330 1164791 NP_699547.1 CDS oxyR NC_004311.2 335293 336246 R similar to GP:4098965, and GP:4098965; identified by sequence similarity; transcriptional regulator OxyR complement(335293..336246) Brucella suis 1330 1164792 NP_699548.1 CDS katA NC_004311.2 336416 337915 D similar to SP:Q59170, GB:L08666, SP:P45880, PID:190200, and PID:190201; identified by sequence similarity; catalase 336416..337915 Brucella suis 1330 1164793 NP_699549.1 CDS BRA0356 NC_004311.2 338010 338219 D similar to GP:9082308; identified by sequence similarity; hypothetical protein 338010..338219 Brucella suis 1330 1164794 NP_699550.1 CDS BRA0357 NC_004311.2 338248 338874 D identified by match to PFAM protein family HMM PF02600; disulfide bond formation protein DsbB 338248..338874 Brucella suis 1330 1164795 NP_699551.1 CDS BRA0358 NC_004311.2 339051 340340 D identified by match to TIGR protein family HMM TIGR00563; sun protein 339051..340340 Brucella suis 1330 1164796 NP_699552.1 CDS BRA0359 NC_004311.2 340631 341086 D identified by match to PFAM protein family HMM PF02584; hypothetical protein 340631..341086 Brucella suis 1330 1164797 NP_699553.1 CDS BRA0360 NC_004311.2 341083 341715 D Enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 341083..341715 Brucella suis 1330 1164798 NP_699554.1 CDS guaA NC_004311.2 341824 343386 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 341824..343386 Brucella suis 1330 1164799 NP_699555.1 CDS BRA0362 NC_004311.2 343695 344903 D identified by match to PFAM protein family HMM PF00589; phage integrase site specific recombinase 343695..344903 Brucella suis 1330 1164800 NP_699556.1 CDS BRA0363 NC_004311.2 345188 345418 D similar to SP:P37447, GB:X76902, and PID:436890; identified by sequence similarity; DNA-binding protein 345188..345418 Brucella suis 1330 1164801 NP_699557.1 CDS BRA0364 NC_004311.2 345499 346557 D similar to GP:8117186, and GP:8117186; identified by sequence similarity; repA-like protein 345499..346557 Brucella suis 1330 1164802 NP_699558.1 CDS BRA0365 NC_004311.2 347606 347932 R hypothetical protein complement(347606..347932) Brucella suis 1330 1164803 NP_699559.1 CDS BRA0366 NC_004311.2 347935 349578 R similar to GB:X72841, SP:P31149, SP:Q09028, SP:Q16576, PID:1016273, and PID:297904; identified by sequence similarity; trbL protein complement(347935..349578) Brucella suis 1330 1164804 NP_699560.1 CDS BRA0367 NC_004311.2 349581 349763 R hypothetical protein complement(349581..349763) Brucella suis 1330 1164805 NP_699561.1 CDS BRA0368 NC_004311.2 349766 350557 R similar to SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, PID:43821, SP:P03833, GB:X01007, GB:X13109, GB:X16345, GB:Y00525, and PID:43821; identified by sequence similarity; trbJ protein complement(349766..350557) Brucella suis 1330 1164806 NP_699562.1 CDS BRA0369 NC_004311.2 350655 350807 D hypothetical protein 350655..350807 Brucella suis 1330 1164807 NP_699563.1 CDS BRA0370 NC_004311.2 350825 351049 R hypothetical protein complement(350825..351049) Brucella suis 1330 1164808 NP_699564.1 CDS BRA0371 NC_004311.2 351052 351270 R similar to GP:14523605, GB:L33243, GB:L43601, GB:L43602, GB:L43604, GB:L43605, GB:L43610, GB:L43617, GB:L43618, SP:P98161, PID:799335, PID:903758, and PID:904223; identified by sequence similarity; traC protein complement(351052..351270) Brucella suis 1330 1164809 NP_699565.1 CDS BRA0372 NC_004311.2 351940 352320 D similar to SP:P17909; identified by sequence similarity; traJ protein 351940..352320 Brucella suis 1330 1164810 NP_699566.1 CDS BRA0373 NC_004311.2 352317 354269 D similar to GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, PID:587442, GB:X62949, GB:L35249, SP:P15313, SP:P21281, PID:179563, PID:37794, PID:522193, and PID:587442; identified by sequence similarity; traI protein 352317..354269 Brucella suis 1330 1164811 NP_699567.1 CDS BRA0374 NC_004311.2 354676 356100 R hypothetical protein complement(354676..356100) Brucella suis 1330 1164812 NP_699568.1 CDS BRA0375 NC_004311.2 356254 357279 R hypothetical protein complement(356254..357279) Brucella suis 1330 1164813 NP_699569.1 CDS BRA0376 NC_004311.2 357313 358038 R hypothetical protein complement(357313..358038) Brucella suis 1330 1164814 NP_699570.1 CDS BRA0377 NC_004311.2 358217 359938 R identified by match to TIGR protein family HMM TIGR00634; hypothetical protein complement(358217..359938) Brucella suis 1330 1164815 NP_699571.1 CDS BRA0378 NC_004311.2 360180 361004 R hypothetical protein complement(360180..361004) Brucella suis 1330 1164816 NP_699572.1 CDS BRA0379 NC_004311.2 361149 361343 R similar to GB:M23326, GB:X15261, GB:X13954, PID:1049195, PID:2358067, PID:312412, PID:37046, PID:37048, PID:37298, PID:37324, and PID:540457; identified by sequence similarity; DNA-damage-inducible protein J complement(361149..361343) Brucella suis 1330 1164817 NP_699573.1 CDS BRA0380 NC_004311.2 361753 361938 D hypothetical protein 361753..361938 Brucella suis 1330 1164818 NP_699574.1 CDS BRA0381 NC_004311.2 362050 362598 D similar to GB:D14695, and PID:285961; identified by sequence similarity; membrane antigen 362050..362598 Brucella suis 1330 1164819 NP_699575.1 CDS BRA0382 NC_004311.2 362602 363000 D similar to GB:M20730, SP:P16534, GB:M24197, PID:150496, and PID:150515; identified by sequence similarity; hypothetical protein 362602..363000 Brucella suis 1330 1164820 NP_699576.1 CDS BRA0383 NC_004311.2 363007 363843 D similar to GP:6469262, and GP:6469262; identified by sequence similarity; FTR1 family iron permease 363007..363843 Brucella suis 1330 1164821 NP_699577.1 CDS BRA0384 NC_004311.2 363804 365237 D similar to SP:P35097, and GB:Z47792; identified by sequence similarity; hypothetical protein 363804..365237 Brucella suis 1330 1164822 NP_699578.1 CDS xfp NC_004311.2 365495 367864 R similar to SP:Q9AEM9; identified by sequence similarity; phosphoketolase complement(365495..367864) Brucella suis 1330 1164823 NP_699579.1 CDS BRA0386 NC_004311.2 367894 369099 R Enables the production of acetyl-CoA by phosphorylating acetate in the presence of ATP and a divalent cation; acetate kinase complement(367894..369099) Brucella suis 1330 1164824 NP_699580.1 CDS BRA0387 NC_004311.2 369338 369499 D hypothetical protein 369338..369499 Brucella suis 1330 1164825 NP_699581.1 CDS BRA0388 NC_004311.2 369542 370705 D identified by match to PFAM protein family HMM PF00067; heme-thiolate monooxygenase 369542..370705 Brucella suis 1330 1164826 NP_699582.1 CDS BRA0389 NC_004311.2 370776 371453 R similar to GP:14524114; identified by sequence similarity; GntR family transcriptional regulator complement(370776..371453) Brucella suis 1330 1164827 NP_699583.1 CDS BRA0390 NC_004311.2 371511 371732 D hypothetical protein 371511..371732 Brucella suis 1330 1164828 NP_699584.1 CDS BRA0391 NC_004311.2 371725 372732 D identified by match to TIGR protein family HMM TIGR00692; alcohol dehydrogenase 371725..372732 Brucella suis 1330 1164829 NP_699585.1 CDS BRA0392 NC_004311.2 372816 374027 D similar to SP:P04816, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 372816..374027 Brucella suis 1330 1164830 NP_699586.1 CDS BRA0393 NC_004311.2 374076 374960 D similar to GP:19715091; identified by sequence similarity; branched-chain amino acid ABC transporter permease 374076..374960 Brucella suis 1330 1164831 NP_699587.1 CDS BRA0395 NC_004311.2 376794 377498 D similar to SP:P22731; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 376794..377498 Brucella suis 1330 1164833 NP_699588.1 CDS fabG NC_004311.2 377501 378298 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 377501..378298 Brucella suis 1330 1164834 NP_699589.1 CDS BRA0397 NC_004311.2 378303 379121 D identified by match to PFAM protein family HMM PF00745; shikimate dehydrogenase 378303..379121 Brucella suis 1330 1164835 NP_699590.1 CDS BRA0398 NC_004311.2 379126 380760 D identified by match to PFAM protein family HMM PF00070; GMC family oxidoreductase 379126..380760 Brucella suis 1330 1164836 NP_699591.1 CDS BRA0399 NC_004311.2 380785 382215 D similar to GP:15159844; identified by sequence similarity; aldehyde dehydrogenase 380785..382215 Brucella suis 1330 1164837 NP_699592.1 CDS BRA0400 NC_004311.2 382307 383470 D similar to SP:P02917, GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 382307..383470 Brucella suis 1330 1164838 NP_699593.1 CDS BRA0401 NC_004311.2 383533 384660 D similar to GP:15075876; identified by sequence similarity; alcohol dehydrogenase 383533..384660 Brucella suis 1330 1164839 NP_699594.1 CDS BRA0402 NC_004311.2 384865 385860 D similar to SP:P49307; identified by sequence similarity; oxidoreductase 384865..385860 Brucella suis 1330 1164840 NP_699595.1 CDS BRA0403 NC_004311.2 385848 387134 D identified by match to PFAM protein family HMM PF01408; Gfo/Idh/MocA family oxidoreductase 385848..387134 Brucella suis 1330 1164841 NP_699596.1 CDS BRA0404 NC_004311.2 386912 387865 R similar to SP:P24137, GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; peptide ABC transporter ATP-binding protein complement(386912..387865) Brucella suis 1330 1164842 NP_699597.1 CDS BRA0405 NC_004311.2 387862 388878 R similar to GB:M88627, SP:P43334, and PID:476741; identified by sequence similarity; peptide ABC transporter ATP-binding protein complement(387862..388878) Brucella suis 1330 1164843 NP_699598.1 CDS BRA0406 NC_004311.2 388889 389806 R similar to GP:12541464; identified by sequence similarity; dihydrodipicolinate synthase complement(388889..389806) Brucella suis 1330 1164844 NP_699599.1 CDS BRA0407 NC_004311.2 389826 390734 R similar to GP:15160372; identified by sequence similarity; peptide ABC transporter permease complement(389826..390734) Brucella suis 1330 1164845 NP_699600.1 CDS BRA0408 NC_004311.2 390700 391659 R similar to GB:X07820, SP:P09238, and PID:36629; identified by sequence similarity; peptide ABC transporter permease complement(390700..391659) Brucella suis 1330 1164846 NP_699601.1 CDS BRA0409 NC_004311.2 391759 393342 R similar to GP:15158790, and GP:6969001; identified by sequence similarity; peptide ABC transporter substrate-binding protein complement(391759..393342) Brucella suis 1330 1164847 NP_699602.1 CDS BRA0410 NC_004311.2 393339 394067 R identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator complement(393339..394067) Brucella suis 1330 1164848 NP_699603.1 CDS BRA0411 NC_004311.2 394227 395804 D identified by match to PFAM protein family HMM PF00218; ROK family protein 394227..395804 Brucella suis 1330 1164849 NP_699604.1 CDS BRA0413 NC_004311.2 397094 397369 D hypothetical protein 397094..397369 Brucella suis 1330 1164851 NP_699605.1 CDS BRA0414 NC_004311.2 397370 398128 R similar to GP:5478244, and GP:5478244; identified by sequence similarity; Crp/Fnr family transcriptional regulator complement(397370..398128) Brucella suis 1330 1164852 NP_699606.1 CDS BRA0415 NC_004311.2 398491 399258 D similar to GP:5478243, and GP:5478243; identified by sequence similarity; LuxR family transcriptional regulator 398491..399258 Brucella suis 1330 1164853 NP_699607.1 CDS BRA0416 NC_004311.2 399295 401484 D similar to GP:5478242, and GP:5478242; identified by sequence similarity; exopolysaccharide biosynthesis protein Bme12 399295..401484 Brucella suis 1330 1164854 NP_699608.1 CDS BRA0417 NC_004311.2 401494 402741 D similar to GP:5478241, GP:5478241, GB:M83667, SP:P49716, and PID:189176; identified by sequence similarity; exopolysaccharide biosynthesis protein Bme11 401494..402741 Brucella suis 1330 1164855 NP_699609.1 CDS BRA0418 NC_004311.2 402846 403826 R similar to GP:5478240; identified by sequence similarity; fucose synthetase complement(402846..403826) Brucella suis 1330 1164856 NP_699610.1 CDS BRA0419 NC_004311.2 403810 404880 R similar to GP:5478239, and SP:P15527; identified by sequence similarity; GDP-mannose 4,6-dehydratase Bme9 complement(403810..404880) Brucella suis 1330 1164857 NP_699611.1 CDS BRA0421 NC_004311.2 406415 407650 D similar to GP:5478237, and GP:5478237; identified by sequence similarity; group 1 glycosyl transferase 406415..407650 Brucella suis 1330 1164859 NP_699612.1 CDS BRA0422 NC_004311.2 407647 408843 D similar to GP:5478236, and GP:5478236; identified by sequence similarity; group 1 glycosyl transferase 407647..408843 Brucella suis 1330 1164860 NP_699613.1 CDS omp31-2 NC_004311.2 408914 409636 R similar to GB:X70959, SP:P42459, PID:452384, GB:X70959, SP:P42459, and PID:452384; identified by sequence similarity; hypothetical protein complement(408914..409636) Brucella suis 1330 1164861 NP_699614.1 CDS BRA0424 NC_004311.2 410033 410647 R similar to GP:5478235; identified by sequence similarity; acetyltransferase complement(410033..410647) Brucella suis 1330 1164862 NP_699615.1 CDS BRA0426 NC_004311.2 411918 412535 R similar to GP:5478233, and GP:5478233; identified by sequence similarity; Bme2 protein complement(411918..412535) Brucella suis 1330 1164864 NP_699616.1 CDS BRA0427 NC_004311.2 412532 413413 R similar to GP:5478232; identified by sequence similarity; glycosyl transferase group 2 family protein complement(412532..413413) Brucella suis 1330 1164865 NP_699617.1 CDS BRA0428 NC_004311.2 413410 414537 R similar to GP:15158359, GB:J00109, GB:K03512, GB:M28637, GB:A15601, GB:K03513, GB:A11954, GB:X15943, SP:P01258, SP:P06881, PID:1340176, PID:179799, PID:179828, PID:180466, PID:296638, and PID:457134; identified by sequence similarity; undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase complement(413410..414537) Brucella suis 1330 1164866 NP_699618.1 CDS BRA0429 NC_004311.2 414830 416323 D similar to GP:15158365; identified by sequence similarity; polysaccharide biosynthesis protein 414830..416323 Brucella suis 1330 1164867 NP_699619.1 CDS BRA0430 NC_004311.2 416339 417352 D similar to GP:15158366; identified by sequence similarity; glycosyl transferase group 2 family protein 416339..417352 Brucella suis 1330 1164868 NP_699620.1 CDS BRA0431 NC_004311.2 417308 418549 R similar to GP:15158364, and GP:15158364; identified by sequence similarity; hypothetical protein complement(417308..418549) Brucella suis 1330 1164869 NP_699621.1 CDS BRA0432 NC_004311.2 418666 420045 D similar to GP:15158361; identified by sequence similarity; group 1 glycosyl transferase 418666..420045 Brucella suis 1330 1164870 NP_699622.1 CDS BRA0433 NC_004311.2 420083 421444 D catalyzes the formation of 5-aminovulinate from (S)-4-amino-5-oxopentanoate; glutamate-1-semialdehyde 2,1-aminomutase 420083..421444 Brucella suis 1330 1164871 NP_699623.1 CDS BRA0434 NC_004311.2 421423 422757 D similar to GP:15158360, and GP:15158360; identified by sequence similarity; hypothetical protein 421423..422757 Brucella suis 1330 1164872 NP_699624.1 CDS BRA0435 NC_004311.2 422878 423939 D similar to GP:15158370; identified by sequence similarity; epimerase 422878..423939 Brucella suis 1330 1164873 NP_699625.1 CDS BRA0436 NC_004311.2 423939 425291 D similar to GP:15158371, and GP:15158371; identified by sequence similarity; hypothetical protein 423939..425291 Brucella suis 1330 1164874 NP_699626.1 CDS rfbC NC_004311.2 425254 425778 R similar to SP:P29202, and PID:148782; identified by sequence similarity; dTDP-4-dehydrorhamnose 3,5-epimerase complement(425254..425778) Brucella suis 1330 1164875 NP_699627.1 CDS BRA0438 NC_004311.2 426099 427400 D similar to GP:15158375; identified by sequence similarity; methyltransferase 426099..427400 Brucella suis 1330 1164876 NP_699628.1 CDS BRA0439 NC_004311.2 427403 428212 D similar to GP:15158376; identified by sequence similarity; nucleotidyltransferase 427403..428212 Brucella suis 1330 1164877 NP_699629.1 CDS BRA0440 NC_004311.2 428209 428865 D similar to GP:15158377, and GP:6066675; identified by sequence similarity; hypothetical protein 428209..428865 Brucella suis 1330 1164878 NP_699630.1 CDS BRA0441 NC_004311.2 428933 429064 D hypothetical protein 428933..429064 Brucella suis 1330 1164879 NP_699631.1 CDS BRA0442 NC_004311.2 429061 430341 R similar to GP:15160336; identified by sequence similarity; uracil-xanthine permease complement(429061..430341) Brucella suis 1330 1164880 NP_699632.1 CDS glpK NC_004311.2 430458 431954 R similar to SP:O66131; identified by sequence similarity; glycerol kinase complement(430458..431954) Brucella suis 1330 1164881 NP_699633.1 CDS BRA0444 NC_004311.2 432081 433382 R identified by match to PFAM protein family HMM PF04024; major facilitator family transporter complement(432081..433382) Brucella suis 1330 1164882 NP_699634.1 CDS BRA0445 NC_004311.2 433487 434374 D similar to GP:4106617; identified by sequence similarity; LysR family transcriptional regulator 433487..434374 Brucella suis 1330 1164883 NP_699635.1 CDS BRA0446 NC_004311.2 434459 434899 D this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; methionine sulfoxide reductase B 434459..434899 Brucella suis 1330 1164884 NP_699636.1 CDS BRA0447 NC_004311.2 434900 436027 R similar to GP:15159873, and SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase complement(434900..436027) Brucella suis 1330 1164885 NP_699637.1 CDS phbA-2 NC_004311.2 436027 437217 R similar to GB:X03342, SP:P02433, and PID:36132; identified by sequence similarity; acetyl-CoA acetyltransferase complement(436027..437217) Brucella suis 1330 1164886 NP_699638.1 CDS BRA0449 NC_004311.2 437286 438053 R similar to GP:9948613, GB:M29297, and SP:P20189; identified by sequence similarity; 3-hydroxyacyl-CoA dehydrogenase complement(437286..438053) Brucella suis 1330 1164887 NP_699639.1 CDS BRA0450 NC_004311.2 438066 439736 R similar to GB:M25667, GB:S66533, GB:S66534, GB:S66541, SP:P17677, and PID:182970; identified by sequence similarity; acetyl-CoA synthetase complement(438066..439736) Brucella suis 1330 1164888 NP_699640.1 CDS BRA0451 NC_004311.2 439863 440846 D similar to GP:14523919; identified by sequence similarity; AraC family transcriptional regulator 439863..440846 Brucella suis 1330 1164889 NP_699641.1 CDS BRA0452 NC_004311.2 440894 441073 D hypothetical protein 440894..441073 Brucella suis 1330 1164890 NP_699642.1 CDS serA-2 NC_004311.2 441070 442308 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 441070..442308 Brucella suis 1330 1164891 NP_699643.1 CDS def NC_004311.2 442361 442855 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(442361..442855) Brucella suis 1330 1164892 NP_699644.1 CDS BRA0455 NC_004311.2 443601 444542 R similar to GB:Z29635, SP:P46374, PID:455002, GB:Z29635, SP:P46374, and PID:455002; identified by sequence similarity; hypothetical protein complement(443601..444542) Brucella suis 1330 1164893 NP_699645.1 CDS BRA0456 NC_004311.2 444855 445178 D identified by match to PFAM protein family HMM PF01022; ArsR family transcriptional regulator 444855..445178 Brucella suis 1330 1164894 NP_699646.1 CDS BRA0457 NC_004311.2 445178 445585 D similar to GP:14523677, and GP:14523677; identified by sequence similarity; hypothetical protein 445178..445585 Brucella suis 1330 1164895 NP_699647.1 CDS BRA0458 NC_004311.2 445582 446019 D hypothetical protein 445582..446019 Brucella suis 1330 1164896 NP_699648.1 CDS BRA0459 NC_004311.2 446042 446749 R similar to GP:14524042; identified by sequence similarity; GntR family transcriptional regulator complement(446042..446749) Brucella suis 1330 1164897 NP_699649.1 CDS BRA0460 NC_004311.2 446995 448053 D identified by match to PFAM protein family HMM PF01594; hypothetical protein 446995..448053 Brucella suis 1330 1164898 NP_699650.1 CDS BRA0461 NC_004311.2 448181 448369 D hypothetical protein 448181..448369 Brucella suis 1330 1164899 NP_699651.1 CDS BRA0462 NC_004311.2 448672 449391 D identified by match to PFAM protein family HMM PF03130; TetR family transcriptional regulator 448672..449391 Brucella suis 1330 1164900 NP_699652.1 CDS BRA0463 NC_004311.2 449396 450340 D identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein 449396..450340 Brucella suis 1330 1164901 NP_699653.1 CDS BRA0465 NC_004311.2 451261 452394 D similar to GP:17427173; identified by sequence similarity; ABC transporter permease 451261..452394 Brucella suis 1330 1164903 NP_699654.1 CDS BRA0466 NC_004311.2 452432 452830 D similar to GP:15158870, and GP:15074195; identified by sequence similarity; hypothetical protein 452432..452830 Brucella suis 1330 1164904 NP_699655.1 CDS BRA0467 NC_004311.2 452837 453655 R similar to GP:13021750, and SP:Q47539; identified by sequence similarity; taurine ABC transporter permease complement(452837..453655) Brucella suis 1330 1164905 NP_699656.1 CDS BRA0468 NC_004311.2 453648 454415 R similar to SP:P37338, GB:U00096, and PID:1789018; identified by sequence similarity; ABC transporter ATP-binding protein complement(453648..454415) Brucella suis 1330 1164906 NP_699657.1 CDS BRA0469 NC_004311.2 454461 455483 R identified by match to PFAM protein family HMM PF00497; ABC transporter periplasmic substrate-binding protein complement(454461..455483) Brucella suis 1330 1164907 NP_699658.1 CDS BRA0471 NC_004311.2 456341 457972 D similar to GP:15074065; identified by sequence similarity; transporter 456341..457972 Brucella suis 1330 1164909 NP_699659.1 CDS BRA0472 NC_004311.2 457997 459046 D similar to GP:15156118; identified by sequence similarity; HlyD family secretion protein 457997..459046 Brucella suis 1330 1164910 NP_699660.1 CDS BRA0473 NC_004311.2 459118 460542 R identified by match to TIGR protein family HMM TIGR01386; osmolarity sensor protein EnvZ complement(459118..460542) Brucella suis 1330 1164911 NP_699661.1 CDS BRA0474 NC_004311.2 460539 461255 R similar to GP:14023190; identified by sequence similarity; transcriptional regulatory protein OmpR complement(460539..461255) Brucella suis 1330 1164912 NP_699662.1 CDS BRA0475 NC_004311.2 461449 461595 R hypothetical protein complement(461449..461595) Brucella suis 1330 1164913 NP_699663.1 CDS BRA0476 NC_004311.2 461579 461944 D hypothetical protein 461579..461944 Brucella suis 1330 1164914 NP_699664.1 CDS BRA0477 NC_004311.2 461956 462108 D hypothetical protein 461956..462108 Brucella suis 1330 1164915 NP_699665.1 CDS BRA0478 NC_004311.2 462368 462718 D similar to GP:14026911; identified by sequence similarity; hypothetical protein 462368..462718 Brucella suis 1330 1164916 NP_699666.1 CDS BRA0479 NC_004311.2 462841 464037 R similar to GP:15075101; identified by sequence similarity; pyridine nucleotide-disulfide oxidoreductase complement(462841..464037) Brucella suis 1330 1164917 NP_699667.1 CDS BRA0480 NC_004311.2 464120 464569 R similar to GP:15155841; identified by sequence similarity; MarR family transcriptional regulator complement(464120..464569) Brucella suis 1330 1164918 NP_699668.1 CDS BRA0481 NC_004311.2 464851 465630 D similar to GP:15075862; identified by sequence similarity; glyoxalase 464851..465630 Brucella suis 1330 1164919 NP_699669.1 CDS BRA0482 NC_004311.2 465694 465864 R hypothetical protein complement(465694..465864) Brucella suis 1330 1164920 NP_699670.1 CDS BRA0483 NC_004311.2 465911 467344 R similar to GP:15074955; identified by sequence similarity; amino acid carrier protein complement(465911..467344) Brucella suis 1330 1164921 NP_699671.1 CDS BRA0485 NC_004311.2 467328 467627 R hypothetical protein complement(467328..467627) Brucella suis 1330 1164922 NP_699672.1 CDS BRA0484 NC_004311.2 467331 467615 D hypothetical protein 467331..467615 Brucella suis 1330 1164923 NP_699673.1 CDS metA NC_004311.2 467772 468692 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 467772..468692 Brucella suis 1330 1164924 NP_699674.1 CDS BRA0487 NC_004311.2 468760 469749 R similar to GP:15140555; identified by sequence similarity; glycosyl hydrolase complement(468760..469749) Brucella suis 1330 1164925 NP_699675.1 CDS BRA0488 NC_004311.2 470102 471082 R FabF, beta-Ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-ACP synthase complement(470102..471082) Brucella suis 1330 1164926 NP_699676.1 CDS bioA NC_004311.2 471079 472353 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; adenosylmethionine-8-amino-7-oxononanoate aminotransferase complement(471079..472353) Brucella suis 1330 1164927 NP_699677.1 CDS bioD NC_004311.2 472350 472988 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; dithiobiotin synthetase complement(472350..472988) Brucella suis 1330 1164928 NP_699678.1 CDS bioF NC_004311.2 472985 474121 R catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine; 8-amino-7-oxononanoate synthase complement(472985..474121) Brucella suis 1330 1164929 NP_699679.1 CDS bioB NC_004311.2 474118 475104 R similar to GB:L05091, GB:U58682, SP:P25112, PID:1518637, and PID:337403; identified by sequence similarity; biotin synthase complement(474118..475104) Brucella suis 1330 1164930 NP_699680.1 CDS BRA0493 NC_004311.2 475376 475537 D hypothetical protein 475376..475537 Brucella suis 1330 1164931 NP_699681.1 CDS BRA0494 NC_004311.2 475515 475796 R hypothetical protein complement(475515..475796) Brucella suis 1330 1164932 NP_699682.1 CDS BRA0495 NC_004311.2 475893 476006 R hypothetical protein complement(475893..476006) Brucella suis 1330 1164933 NP_699683.1 CDS mogA NC_004311.2 476059 476577 D forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis; molybdenum cofactor biosynthesis protein MogA 476059..476577 Brucella suis 1330 1164934 NP_699684.1 CDS BRA0497 NC_004311.2 476629 477228 R hypothetical protein complement(476629..477228) Brucella suis 1330 1164935 NP_699685.1 CDS BRA0498 NC_004311.2 477295 477414 D hypothetical protein 477295..477414 Brucella suis 1330 1164936 NP_699686.1 CDS BRA0499 NC_004311.2 477552 478880 D identified by match to PFAM protein family HMM PF00070; hypothetical protein 477552..478880 Brucella suis 1330 1164937 NP_699687.1 CDS BRA0500 NC_004311.2 479321 482239 D subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+; monovalent cation/H+ antiporter subunit A 479321..482239 Brucella suis 1330 1164938 NP_699688.1 CDS BRA0501 NC_004311.2 482239 482577 D subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 482239..482577 Brucella suis 1330 1164939 NP_699689.1 CDS BRA0502 NC_004311.2 482580 484208 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 482580..484208 Brucella suis 1330 1164940 NP_699690.1 CDS BRA0503 NC_004311.2 484205 484720 D subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit E 484205..484720 Brucella suis 1330 1164941 NP_699691.1 CDS phaF NC_004311.2 484717 484998 D subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; monovalent cation/H+ antiporter subunit F 484717..484998 Brucella suis 1330 1164942 NP_699692.1 CDS BRA0505 NC_004311.2 484995 485357 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 484995..485357 Brucella suis 1330 1164943 NP_699693.1 CDS BRA0506 NC_004311.2 485374 485706 D hypothetical protein 485374..485706 Brucella suis 1330 1164944 NP_699694.1 CDS BRA0507 NC_004311.2 485782 486318 D similar to GP:15159185, GB:Z27502, GB:Z29983, SP:P04438, PID:1335182, PID:32878, PID:474960, PID:505435, and PID:563647; identified by sequence similarity; hypothetical protein 485782..486318 Brucella suis 1330 1164945 NP_699695.1 CDS cydD NC_004311.2 486426 488051 D similar to GP:9858820, GB:M24400, SP:P17538, and PID:181190; identified by sequence similarity; ABC transporter ATP-binding protein CydD 486426..488051 Brucella suis 1330 1164946 NP_699696.1 CDS BRA0509 NC_004311.2 488048 489730 D similar to GP:9858821; identified by sequence similarity; ABC transporter ATP-binding/permease 488048..489730 Brucella suis 1330 1164947 NP_699697.1 CDS cydA NC_004311.2 489874 491451 D similar to GP:9858822, and SP:P11026; identified by sequence similarity; cytochrome d ubiquinol oxidase subunit I 489874..491451 Brucella suis 1330 1164948 NP_699698.1 CDS cydB NC_004311.2 491457 492611 D similar to GB:X59066, GB:X65460, GB:D28126, GB:D14710, SP:P25705, PID:28938, PID:34468, PID:559317, and PID:559325; identified by sequence similarity; cytochrome d ubiquinol oxidase subunit II 491457..492611 Brucella suis 1330 1164949 NP_699699.1 CDS ybgT NC_004311.2 492589 492783 D similar to SP:P30858, GB:X86160, PID:769790, GB:U00096, PID:1651397, and PID:1787089; identified by sequence similarity; hypothetical protein 492589..492783 Brucella suis 1330 1164950 NP_699700.1 CDS BRA0513 NC_004311.2 492834 493607 R similar to GP:15073129; identified by sequence similarity; GntR family transcriptional regulator complement(492834..493607) Brucella suis 1330 1164951 NP_699701.1 CDS BRA0514 NC_004311.2 493604 494491 R similar to GP:15073128, and GP:15073128; identified by sequence similarity; hypothetical protein complement(493604..494491) Brucella suis 1330 1164952 NP_699702.1 CDS BRA0515 NC_004311.2 494655 494843 D hypothetical protein 494655..494843 Brucella suis 1330 1164953 NP_699703.1 CDS BRA0516 NC_004311.2 494840 496099 D similar to GP:15073126, and SP:Q00749; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 494840..496099 Brucella suis 1330 1164954 NP_699704.1 CDS BRA0517 NC_004311.2 496324 496452 R hypothetical protein complement(496324..496452) Brucella suis 1330 1164955 NP_699705.1 CDS BRA0518 NC_004311.2 496472 497416 D similar to GP:15073125, and SP:P29823; identified by sequence similarity; sugar ABC transporter permease 496472..497416 Brucella suis 1330 1164956 NP_699706.1 CDS BRA0519 NC_004311.2 497429 498268 D similar to GP:15073124; identified by sequence similarity; sugar ABC transporter permease 497429..498268 Brucella suis 1330 1164957 NP_699707.1 CDS BRA0520 NC_004311.2 498265 499335 D similar to GP:15073123; identified by sequence similarity; Gfo/Idh/MocA family oxidoreductase 498265..499335 Brucella suis 1330 1164958 NP_699708.1 CDS BRA0521 NC_004311.2 499365 500366 D similar to GP:15073122, and SP:Q01937; identified by sequence similarity; sugar ABC transporter ATP-binding protein 499365..500366 Brucella suis 1330 1164959 NP_699709.1 CDS BRA0522 NC_004311.2 500419 500670 D hypothetical protein 500419..500670 Brucella suis 1330 1164960 NP_699710.1 CDS BRA0523 NC_004311.2 500472 500639 D hypothetical protein 500472..500639 Brucella suis 1330 1164961 NP_699711.1 CDS BRA0524 NC_004311.2 500967 502199 D similar to GP:15075957, and SP:P09060; identified by sequence similarity; 2-oxoisovalerate dehydrogenase E1 component subunit alpha 500967..502199 Brucella suis 1330 1164962 NP_699712.1 CDS BRA0525 NC_004311.2 502303 503316 D identified by match to PFAM protein family HMM PF02780; 2-oxoisovalerate dehydrogenase E1 502303..503316 Brucella suis 1330 1164963 NP_699713.1 CDS BRA0526 NC_004311.2 503317 504612 D Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA; branched-chain alpha-keto acid dehydrogenase subunit E2 503317..504612 Brucella suis 1330 1164964 NP_699714.1 CDS lpdA-3 NC_004311.2 504617 506011 D E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoamide dehydrogenase 504617..506011 Brucella suis 1330 1164965 NP_699715.1 CDS BRA0528 NC_004311.2 506000 506761 R identified by match to PFAM protein family HMM PF02104; SurF1 family protein complement(506000..506761) Brucella suis 1330 1164966 NP_699716.1 CDS BRA0529 NC_004311.2 507020 507274 D hypothetical protein 507020..507274 Brucella suis 1330 1164967 NP_699717.1 CDS BRA0530 NC_004311.2 507455 509920 R similar to GB:L07807, GB:L07810, GB:L07808, GB:L07809, SP:Q05193, PID:181849, and PID:181851; identified by sequence similarity; DNA translocase FtsK complement(507455..509920) Brucella suis 1330 1164968 NP_699718.1 CDS BRA0531 NC_004311.2 510215 511237 R identified by match to PFAM protein family HMM PF03576; D-aminopeptidase complement(510215..511237) Brucella suis 1330 1164969 NP_699719.1 CDS BRA0532 NC_004311.2 511484 512794 D similar to GP:15157414; identified by sequence similarity; major facilitator family transporter 511484..512794 Brucella suis 1330 1164970 NP_699720.1 CDS alkB NC_004311.2 512953 513591 R similar to GB:J05175, SP:P16442, PID:1783208, PID:1783212, PID:1783214, PID:1783218, PID:1783226, PID:2352626, PID:340078, and PID:992596; identified by sequence similarity; alkylated DNA repair protein AlkB complement(512953..513591) Brucella suis 1330 1164971 NP_699721.1 CDS BRA0534 NC_004311.2 513673 515283 R similar to GP:15158999; identified by sequence similarity; ABC transporter ATP-binding protein complement(513673..515283) Brucella suis 1330 1164972 NP_699722.1 CDS BRA0535 NC_004311.2 515285 516445 R similar to GP:15140749; identified by sequence similarity; oligopeptide ABC transporter permease complement(515285..516445) Brucella suis 1330 1164973 NP_699723.1 CDS BRA0536 NC_004311.2 516411 517334 R similar to GP:15158997, and SP:P24138; identified by sequence similarity; oligopeptide ABC transporter permease complement(516411..517334) Brucella suis 1330 1164974 NP_699724.1 CDS BRA0537 NC_004311.2 517549 519126 R similar to GP:13235555, and SP:P77348; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein complement(517549..519126) Brucella suis 1330 1164975 NP_699725.1 CDS BRA0538 NC_004311.2 519237 520814 R similar to GP:15158996, and SP:P06202; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein complement(519237..520814) Brucella suis 1330 1164976 NP_699726.1 CDS BRA0539 NC_004311.2 520908 521078 R hypothetical protein complement(520908..521078) Brucella suis 1330 1164977 NP_699727.1 CDS BRA0540 NC_004311.2 521241 521588 R similar to GP:15074850; identified by sequence similarity; hypothetical protein complement(521241..521588) Brucella suis 1330 1164978 NP_699728.1 CDS BRA0541 NC_004311.2 521842 522066 R hypothetical protein complement(521842..522066) Brucella suis 1330 1164979 NP_699729.1 CDS BRA0542 NC_004311.2 522383 523396 D similar to GP:15140313; identified by sequence similarity; NAD-dependent epimerase/dehydratase 522383..523396 Brucella suis 1330 1164980 NP_699730.1 CDS galE-2 NC_004311.2 523396 524382 D similar to SP:P23157, GB:X55942, and PID:46921; identified by sequence similarity; UDP-glucose 4-epimerase 523396..524382 Brucella suis 1330 1164981 NP_699731.1 CDS BRA0544 NC_004311.2 524379 526223 D similar to GP:15140315; identified by sequence similarity; glycosyl transferase group 2 family protein 524379..526223 Brucella suis 1330 1164982 NP_699732.1 CDS ugd NC_004311.2 526238 527662 D identified by match to TIGR protein family HMM TIGR00745; UDP-glucose 6-dehydrogenase 526238..527662 Brucella suis 1330 1164983 NP_699733.1 CDS BRA0546 NC_004311.2 527652 528197 D similar to GP:15140316, and GP:15140316; identified by sequence similarity; hypothetical protein 527652..528197 Brucella suis 1330 1164984 NP_699734.1 CDS BRA0547 NC_004311.2 528247 529191 D similar to GP:15140317; identified by sequence similarity; endoglucanase 528247..529191 Brucella suis 1330 1164985 NP_699735.1 CDS BRA0548 NC_004311.2 529188 529805 D similar to GP:15140318, and GP:15140318; identified by sequence similarity; hypothetical protein 529188..529805 Brucella suis 1330 1164986 NP_699736.1 CDS BRA0549 NC_004311.2 529881 530207 R similar to GP:15160059; identified by sequence similarity; hypothetical protein complement(529881..530207) Brucella suis 1330 1164987 NP_699737.1 CDS BRA0550 NC_004311.2 530350 531471 R identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator complement(530350..531471) Brucella suis 1330 1164988 NP_699738.1 CDS BRA0552 NC_004311.2 532262 532573 R similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; IS711, transposase orfA complement(532262..532573) Brucella suis 1330 1164990 NP_699739.1 CDS BRA0553 NC_004311.2 532630 534594 R identified by match to PFAM protein family HMM PF02566; cell wall surface protein complement(532630..534594) Brucella suis 1330 1164991 NP_699740.1 CDS BRA0555 NC_004311.2 535170 535775 R similar to SP:P14040, GB:X15970, and PID:44784; identified by sequence similarity; IS66 family orf4 complement(535170..535775) Brucella suis 1330 1164993 NP_699741.1 CDS BRA0556 NC_004311.2 535772 537343 R similar to GP:15140549, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; IS66 family orf3 complement(535772..537343) Brucella suis 1330 1164994 NP_699742.1 CDS BRA0557 NC_004311.2 537393 537779 R similar to GP:15076151, SP:P37811, GB:Z28592, PID:433988, and GB:AL009126; identified by sequence similarity; IS66 family orf2 complement(537393..537779) Brucella suis 1330 1164995 NP_699743.1 CDS BRA0558 NC_004311.2 537743 538210 R similar to GP:15076150, and GP:15076150; identified by sequence similarity; IS66 family Orf1 complement(537743..538210) Brucella suis 1330 1164996 NP_699744.1 CDS BRA0560 NC_004311.2 539354 539827 D hypothetical protein 539354..539827 Brucella suis 1330 1164998 NP_699745.1 CDS BRA0561 NC_004311.2 540300 540758 D identified by match to TIGR protein family HMM TIGR00011; hypothetical protein 540300..540758 Brucella suis 1330 1165000 NP_699746.1 CDS rirA NC_004311.2 541004 541465 D rhizobial iron regulator; in Sinorhizobium meliloti mutations in this gene affect the expression of a number of iron-responsive operons; iron-responsive transcriptional regulator 541004..541465 Brucella suis 1330 1165001 NP_699747.1 CDS BRA0563 NC_004311.2 541582 541896 D similar to GP:13277326, and GP:13277326; identified by sequence similarity; hypothetical protein 541582..541896 Brucella suis 1330 1165002 NP_699748.1 CDS BRA0564 NC_004311.2 542353 542664 D similar to GP:15076196; identified by sequence similarity; hypothetical protein 542353..542664 Brucella suis 1330 1165003 NP_699749.1 CDS bfr NC_004311.2 542630 543115 D similar to SP:P22759; identified by sequence similarity; bacterioferritin 542630..543115 Brucella suis 1330 1165004 NP_699750.1 CDS rimO NC_004311.2 543279 544592 D catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit; ribosomal protein S12 methylthiotransferase 543279..544592 Brucella suis 1330 1165005 NP_699751.1 CDS BRA0567 NC_004311.2 544732 545799 R similar to GP:15156897; identified by sequence similarity; bmp family protein complement(544732..545799) Brucella suis 1330 1165006 NP_699752.1 CDS BRA0568 NC_004311.2 545882 546802 R similar to GP:15156898; identified by sequence similarity; ABC transporter permease complement(545882..546802) Brucella suis 1330 1165007 NP_699753.1 CDS BRA0569 NC_004311.2 546807 547889 R similar to GP:13937515; identified by sequence similarity; ABC transporter permease complement(546807..547889) Brucella suis 1330 1165008 NP_699754.1 CDS BRA0570 NC_004311.2 547889 549451 R similar to GP:13937516; identified by sequence similarity; ABC transporter ATP-binding protein complement(547889..549451) Brucella suis 1330 1165009 NP_699755.1 CDS qor NC_004311.2 549555 550529 R similar to GP:15074605; identified by sequence similarity; quinone oxidoreductase complement(549555..550529) Brucella suis 1330 1165010 NP_699756.1 CDS pcs NC_004311.2 550526 551326 R similar to GP:6739568; identified by sequence similarity; phosphatidylcholine synthase complement(550526..551326) Brucella suis 1330 1165011 NP_699757.1 CDS ubiH NC_004311.2 551542 552900 D similar to SP:P25534; identified by sequence similarity; 2-octaprenyl-6-methoxyphenyl hydroxylase 551542..552900 Brucella suis 1330 1165012 NP_699758.1 CDS BRA0574 NC_004311.2 552973 553311 D similar to GP:15074574; identified by sequence similarity; hypothetical protein 552973..553311 Brucella suis 1330 1165013 NP_699759.1 CDS BRA0575 NC_004311.2 553444 554061 R similar to GP:14021474; identified by sequence similarity; hypothetical protein complement(553444..554061) Brucella suis 1330 1165014 NP_699760.1 CDS BRA0576 NC_004311.2 554406 556253 D similar to GP:15074576; identified by sequence similarity; peptide ABC transporter substrate-binding protein 554406..556253 Brucella suis 1330 1165015 NP_699761.1 CDS BRA0577 NC_004311.2 556433 557107 D identified by match to PFAM protein family HMM PF03046; frnE protein 556433..557107 Brucella suis 1330 1165016 NP_699762.1 CDS BRA0578 NC_004311.2 557283 557681 R identified by match to PFAM protein family HMM PF00903; fosfomycin resistance family protein complement(557283..557681) Brucella suis 1330 1165017 NP_699763.1 CDS mfd NC_004311.2 557774 561142 R identified by match to TIGR protein family HMM TIGR01587; transcription-repair coupling factor complement(557774..561142) Brucella suis 1330 1165018 NP_699764.1 CDS BRA0580 NC_004311.2 561297 561584 R similar to GP:15074586, and GP:15074586; identified by sequence similarity; hypothetical protein complement(561297..561584) Brucella suis 1330 1165019 NP_699765.1 CDS recG NC_004311.2 561723 563843 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 561723..563843 Brucella suis 1330 1165020 NP_699766.1 CDS glmS NC_004311.2 563998 565821 R Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase complement(563998..565821) Brucella suis 1330 1165021 NP_699767.1 CDS glmU NC_004311.2 565925 567289 R forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase complement(565925..567289) Brucella suis 1330 1165022 NP_699768.1 CDS ccdA NC_004311.2 567371 568132 R similar to GP:6714962; identified by sequence similarity; cytochrome c-type biogenesis protein CcdA complement(567371..568132) Brucella suis 1330 1165023 NP_699769.1 CDS BRA0585 NC_004311.2 568281 570923 D similar to GP:15074112; identified by sequence similarity; hypothetical protein 568281..570923 Brucella suis 1330 1165024 NP_699770.1 CDS BRA0586 NC_004311.2 571172 572332 D similar to GP:15157711, and GP:1196970; identified by sequence similarity; hypothetical protein 571172..572332 Brucella suis 1330 1165025 NP_699771.1 CDS BRA0587 NC_004311.2 572836 573336 R similar to GP:3236220; identified by sequence similarity; hypothetical protein complement(572836..573336) Brucella suis 1330 1165027 NP_699772.1 CDS BRA0588 NC_004311.2 573654 575045 D identified by match to PFAM protein family HMM PF00989; sensory box protein 573654..575045 Brucella suis 1330 1165028 NP_699773.1 CDS lipB NC_004311.2 575173 575976 D lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein; lipoate-protein ligase B 575173..575976 Brucella suis 1330 1165029 NP_699774.1 CDS BRA0590 NC_004311.2 575980 576909 R similar to GP:15156645; identified by sequence similarity; hypothetical protein complement(575980..576909) Brucella suis 1330 1165030 NP_699775.1 CDS parE NC_004311.2 577214 579313 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 577214..579313 Brucella suis 1330 1165031 NP_699776.1 CDS BRA0592 NC_004311.2 579319 579501 R hypothetical protein complement(579319..579501) Brucella suis 1330 1165032 NP_699777.1 CDS BRA0593 NC_004311.2 579486 579710 R hypothetical protein complement(579486..579710) Brucella suis 1330 1165033 NP_699778.1 CDS gatA NC_004311.2 579735 581216 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(579735..581216) Brucella suis 1330 1165034 NP_699779.1 CDS gatC NC_004311.2 581275 581562 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(581275..581562) Brucella suis 1330 1165035 NP_699780.1 CDS BRA0596 NC_004311.2 581657 582370 R catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase complement(581657..582370) Brucella suis 1330 1165036 NP_699781.1 CDS BRA0597 NC_004311.2 582470 582958 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 582470..582958 Brucella suis 1330 1165037 NP_699782.1 CDS BRA0598 NC_004311.2 582943 584598 R identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase complement(582943..584598) Brucella suis 1330 1165038 NP_699783.1 CDS pyrB NC_004311.2 584755 585723 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 584755..585723 Brucella suis 1330 1165039 NP_699784.1 CDS pyrC-2 NC_004311.2 585720 587006 D Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; dihydroorotase 585720..587006 Brucella suis 1330 1165040 NP_699785.1 CDS BRA0601 NC_004311.2 587081 587686 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY 587081..587686 Brucella suis 1330 1165041 NP_699786.1 CDS BRA0602 NC_004311.2 587683 588864 D similar to GP:15156358; identified by sequence similarity; DNA processing protein DprA 587683..588864 Brucella suis 1330 1165042 NP_699787.1 CDS BRA0603 NC_004311.2 588874 589041 R hypothetical protein complement(588874..589041) Brucella suis 1330 1165043 NP_699788.1 CDS topA NC_004311.2 589297 591930 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 589297..591930 Brucella suis 1330 1165044 NP_699789.1 CDS BRA0605 NC_004311.2 591934 594285 D similar to SP:P21499; identified by sequence similarity; VacB/RNase II family exoribonuclease 591934..594285 Brucella suis 1330 1165045 NP_699790.1 CDS BRA0606 NC_004311.2 594285 594746 D hypothetical protein 594285..594746 Brucella suis 1330 1165046 NP_699791.1 CDS BRA0607 NC_004311.2 594755 595486 D similar to GP:6525218; identified by sequence similarity; MutT/nudix family protein 594755..595486 Brucella suis 1330 1165047 NP_699792.1 CDS BRA0608 NC_004311.2 595561 596703 D similar to GP:6525219; identified by sequence similarity; major facilitator family transporter 595561..596703 Brucella suis 1330 1165048 NP_699793.1 CDS rpmG NC_004311.2 596862 597029 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 596862..597029 Brucella suis 1330 1165049 NP_699794.1 CDS pleD NC_004311.2 597136 598521 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(597136..598521) Brucella suis 1330 1165050 NP_699795.1 CDS BRA0611 NC_004311.2 598518 598649 R hypothetical protein complement(598518..598649) Brucella suis 1330 1165051 NP_699796.1 CDS divK NC_004311.2 598642 599013 R similar to GP:6513589; identified by sequence similarity; polar differentiation response regulator complement(598642..599013) Brucella suis 1330 1165052 NP_699797.1 CDS BRA0613 NC_004311.2 599116 599481 D similar to GP:15074224; identified by sequence similarity; hypothetical protein 599116..599481 Brucella suis 1330 1165053 NP_699798.1 CDS BRA0614 NC_004311.2 599537 600046 R Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation; nucleoside diphosphate kinase regulator complement(599537..600046) Brucella suis 1330 1165054 NP_699799.1 CDS BRA0615 NC_004311.2 600497 601834 D involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 600497..601834 Brucella suis 1330 1165055 NP_699800.1 CDS BRA0616 NC_004311.2 602010 604199 D similar to GP:15156313, and GP:15074191; identified by sequence similarity; hypothetical protein 602010..604199 Brucella suis 1330 1165056 NP_699801.1 CDS BRA0617 NC_004311.2 604179 604301 R hypothetical protein complement(604179..604301) Brucella suis 1330 1165057 NP_699802.1 CDS BRA0618 NC_004311.2 604728 605450 R identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein complement(604728..605450) Brucella suis 1330 1165059 NP_699803.1 CDS BRA0619 NC_004311.2 606123 606221 R hypothetical protein complement(606123..606221) Brucella suis 1330 1165060 NP_699804.1 CDS BRA0620 NC_004311.2 606257 606370 R hypothetical protein complement(606257..606370) Brucella suis 1330 1165061 NP_699805.1 CDS BRA0621 NC_004311.2 606348 606725 R similar to SP:P09795, and PID:154350; identified by sequence similarity; endonuclease V complement(606348..606725) Brucella suis 1330 1165062 NP_699806.1 CDS BRA0622 NC_004311.2 606866 607171 D hypothetical protein 606866..607171 Brucella suis 1330 1165063 NP_699807.1 CDS BRA0623 NC_004311.2 607316 607504 D hypothetical protein 607316..607504 Brucella suis 1330 1165064 NP_699809.1 CDS BRA0625 NC_004311.2 607555 607848 D hypothetical protein 607555..607848 Brucella suis 1330 1165066 NP_699810.1 CDS BRA0626 NC_004311.2 607942 608616 D identified by match to TIGR protein family HMM TIGR01406; exonuclease 607942..608616 Brucella suis 1330 1165067 NP_699811.1 CDS BRA0627 NC_004311.2 608992 609273 D similar to GP:15074546, and GP:15074546; identified by sequence similarity; hypothetical protein 608992..609273 Brucella suis 1330 1165069 NP_699812.1 CDS BRA0628 NC_004311.2 609374 610333 R identified by match to PFAM protein family HMM PF00165; AraC family transcriptional regulator complement(609374..610333) Brucella suis 1330 1165070 NP_699813.1 CDS BRA0629 NC_004311.2 610501 610662 R hypothetical protein complement(610501..610662) Brucella suis 1330 1165071 NP_699814.1 CDS BRA0630 NC_004311.2 610688 611938 R similar to GP:15073672, and SP:Q98B75; identified by sequence similarity; amino acid dehydrogenase complement(610688..611938) Brucella suis 1330 1165072 NP_699815.1 CDS BRA0631 NC_004311.2 612027 612788 R similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; amino acid ABC transporter substrate-binding protein complement(612027..612788) Brucella suis 1330 1165073 NP_699816.1 CDS BRA0632 NC_004311.2 612944 613717 R similar to SP:P33548, PID:155324, and PID:155328; identified by sequence similarity; amino acid ABC transporter substrate-binding protein complement(612944..613717) Brucella suis 1330 1165074 NP_699817.1 CDS BRA0633 NC_004311.2 613902 615005 R identified by match to PFAM protein family HMM PF00899; hypothetical protein complement(613902..615005) Brucella suis 1330 1165075 NP_699818.1 CDS BRA0634 NC_004311.2 615107 615556 D identified by match to PFAM protein family HMM PF01047; AsnC family transcriptional regulator 615107..615556 Brucella suis 1330 1165076 NP_699819.1 CDS BRA0635 NC_004311.2 615836 617563 D identified by match to TIGR protein family HMM TIGR01409; twin-arginine translocation pathway signal sequence domain-containing protein 615836..617563 Brucella suis 1330 1165077 NP_699820.1 CDS pcaF NC_004311.2 617674 618876 R catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA; beta-ketoadipyl CoA thiolase complement(617674..618876) Brucella suis 1330 1165078 NP_699821.1 CDS pcaJ NC_004311.2 618885 619574 R similar to GP:15158666, and SP:Q01104; identified by sequence similarity; 3-oxoadipate CoA-transferase subunit B complement(618885..619574) Brucella suis 1330 1165079 NP_699822.1 CDS pcaI NC_004311.2 619571 620278 R similar to GP:15158667, and SP:Q01103; identified by sequence similarity; 3-oxoadipate CoA-transferase subunit A complement(619571..620278) Brucella suis 1330 1165080 NP_699823.1 CDS BRA0639 NC_004311.2 620462 621232 D similar to GP:15141386; identified by sequence similarity; transcriptional regulator PcaR 620462..621232 Brucella suis 1330 1165081 NP_699824.1 CDS pobR NC_004311.2 621239 622156 R similar to GP:6682325; identified by sequence similarity; pobR protein complement(621239..622156) Brucella suis 1330 1165082 NP_699825.1 CDS pobA NC_004311.2 622269 623438 D catalyzes the formation of protocatechuate from 4-hydroxybenzoate; 4-hydroxybenzoate 3-monooxygenase 622269..623438 Brucella suis 1330 1165083 NP_699826.1 CDS pcaQ NC_004311.2 623848 624756 R similar to GP:15141380, GB:D21235, SP:P54725, PID:1905912, and PID:498146; identified by sequence similarity; transcriptional regulator PcaQ complement(623848..624756) Brucella suis 1330 1165084 NP_699827.1 CDS pcaL NC_004311.2 624850 625653 D similar to GP:15141379, and SP:P00632; identified by sequence similarity; 3-oxoadipate enol-lactone hydrolase 624850..625653 Brucella suis 1330 1165085 NP_699828.1 CDS pcaC NC_004311.2 625657 626073 D similar to GP:15141378; identified by sequence similarity; 4-carboxymuconolactone decarboxylase 625657..626073 Brucella suis 1330 1165086 NP_699829.1 CDS pcaH NC_004311.2 626070 626810 D similar to GP:11037223, and SP:P00437; identified by sequence similarity; protocatechuate 3,4-dioxygenase subunit beta 626070..626810 Brucella suis 1330 1165087 NP_699830.1 CDS pcaG NC_004311.2 626812 627429 D similar to GP:11037224, GB:M12783, GB:X02811, GB:M19719, GB:X03702, GB:K01918, GB:X03493, GB:Y00389, GB:K01402, GB:X02745, GB:K01399, GB:X00560, GB:K01915, GB:K01917, GB:K01401, GB:X00562, GB:K01916, GB:K01400, GB:X00561, GB:K01913, GB:K01914, GB:J00121, GB:K01398, GB:X02744, GB:M32009, SP:P01127, PID:1335308, PID:1335309, PID:1335310, PID:1335311, PID:1621242, PID:1888419, PID:2294400, PID:2294421, PID:2294425, PID:2297379, PID:30247, PID:338199, PID:338209, PID:338211, PID:35372, PID:35375, PID:35377, PID:36481, and PID:951025; identified by sequence similarity; protocatechuate 3,4-dioxygenase subunit alpha 626812..627429 Brucella suis 1330 1165088 NP_699831.1 CDS BRA0647 NC_004311.2 627433 628497 D Catalyzes the cycloisomerization of cis,cis-muconate; 3-carboxy-cis,cis-muconate cycloisomerase 627433..628497 Brucella suis 1330 1165089 NP_699832.1 CDS BRA0648 NC_004311.2 628633 629805 D similar to GP:15158698; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 628633..629805 Brucella suis 1330 1165090 NP_699833.1 CDS BRA0649 NC_004311.2 629978 630847 D similar to GP:15158699; identified by sequence similarity; branched-chain amino acid ABC transporter permease 629978..630847 Brucella suis 1330 1165091 NP_699834.1 CDS BRA0650 NC_004311.2 630844 631830 D similar to GP:15158700; identified by sequence similarity; branched-chain amino acid ABC transporter permease 630844..631830 Brucella suis 1330 1165092 NP_699835.1 CDS BRA0651 NC_004311.2 631827 632576 D similar to GP:15158701; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 631827..632576 Brucella suis 1330 1165093 NP_699836.1 CDS BRA0652 NC_004311.2 632573 633289 D similar to GP:15158702; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 632573..633289 Brucella suis 1330 1165094 NP_699837.1 CDS ade NC_004311.2 633290 635035 R similar to GB:Y00636, GB:X06296, SP:P19256, PID:34347, PID:34350, and PID:540515; identified by sequence similarity; adenine deaminase complement(633290..635035) Brucella suis 1330 1165095 NP_699838.1 CDS BRA0654 NC_004311.2 635194 636234 D similar to GP:15157708; identified by sequence similarity; renal dipeptidase 635194..636234 Brucella suis 1330 1165096 NP_699839.1 CDS ugpB NC_004311.2 636567 637868 D similar to GP:15140275, and GP:43244; identified by sequence similarity; glycerol-3-phosphate ABC transporter periplasmic glycerol-3-phosphate-binding protein 636567..637868 Brucella suis 1330 1165097 NP_699840.1 CDS ugpA NC_004311.2 637941 638822 D similar to GP:15140276; identified by sequence similarity; glycerol-3-phosphate ABC transporter permease 637941..638822 Brucella suis 1330 1165098 NP_699841.1 CDS ugpE NC_004311.2 638834 639682 D similar to GP:15160208; identified by sequence similarity; glycerol-3-phosphate ABC transporter permease 638834..639682 Brucella suis 1330 1165099 NP_699842.1 CDS ugpC NC_004311.2 639682 640737 D part of the UgpABCE glycerol-3-phosphate uptake system; glycerol-3-phosphate transporter ATP-binding subunit 639682..640737 Brucella suis 1330 1165100 NP_699843.1 CDS BRA0659 NC_004311.2 640911 642770 D similar to GP:15075030; identified by sequence similarity; TrkA family protein 640911..642770 Brucella suis 1330 1165101 NP_699844.1 CDS BRA0660 NC_004311.2 642848 643447 R similar to GP:15074401; identified by sequence similarity; cytidine/deoxycytidylate deaminase complement(642848..643447) Brucella suis 1330 1165102 NP_699845.1 CDS BRA0661 NC_004311.2 643508 644800 R similar to GP:15140670; identified by sequence similarity; uracil-xanthine permease complement(643508..644800) Brucella suis 1330 1165103 NP_699846.1 CDS BRA0662 NC_004311.2 645069 645233 R hypothetical protein complement(645069..645233) Brucella suis 1330 1165104 NP_699847.1 CDS BRA0664 NC_004311.2 645926 646108 D hypothetical protein 645926..646108 Brucella suis 1330 1165106 NP_699848.1 CDS BRA0665 NC_004311.2 646112 646249 R similar to GP:15073153; identified by sequence similarity; hypothetical protein complement(646112..646249) Brucella suis 1330 1165107 NP_699849.1 CDS BRA0666 NC_004311.2 646508 647425 D similar to GP:15156879; identified by sequence similarity; hypothetical protein 646508..647425 Brucella suis 1330 1165108 NP_699850.1 CDS BRA0668 NC_004311.2 648385 648576 D hypothetical protein 648385..648576 Brucella suis 1330 1165110 NP_699851.1 CDS BRA0669 NC_004311.2 648573 649334 D identified by match to PFAM protein family HMM PF03647; hypothetical protein 648573..649334 Brucella suis 1330 1165111 NP_699852.1 CDS BRA0670 NC_004311.2 649406 651061 D proposed role in polysaccahride synthesis; FAD-binding dehydrogenase 649406..651061 Brucella suis 1330 1165112 NP_699853.1 CDS BRA0671 NC_004311.2 651070 651594 D hypothetical protein 651070..651594 Brucella suis 1330 1165113 NP_699855.1 CDS BRA0673 NC_004311.2 651808 653166 D similar to GP:15075528; identified by sequence similarity; aldehyde dehydrogenase 651808..653166 Brucella suis 1330 1165115 NP_699856.1 CDS BRA0674 NC_004311.2 653475 653585 D hypothetical protein 653475..653585 Brucella suis 1330 1165116 NP_699857.1 CDS BRA0675 NC_004311.2 653644 654591 D similar to GP:15157658, and SP:P15028; identified by sequence similarity; iron ABC transporter substrate-binding protein 653644..654591 Brucella suis 1330 1165117 NP_699858.1 CDS BRA0676 NC_004311.2 654648 655610 D similar to GP:15157659, and SP:P37738; identified by sequence similarity; iron ABC transporter permease 654648..655610 Brucella suis 1330 1165118 NP_699859.1 CDS BRA0677 NC_004311.2 655603 656556 D similar to GP:15157660, and SP:P37737; identified by sequence similarity; iron ABC transporter permease 655603..656556 Brucella suis 1330 1165119 NP_699860.1 CDS BRA0678 NC_004311.2 656553 657311 D similar to GP:15157661, and GP:15023678; identified by sequence similarity; iron ABC transporter ATP-binding protein 656553..657311 Brucella suis 1330 1165120 NP_699861.1 CDS BRA0679 NC_004311.2 657364 657963 R similar to GP:14023727; identified by sequence similarity; hypothetical protein complement(657364..657963) Brucella suis 1330 1165121 NP_699862.1 CDS BRA0680 NC_004311.2 657994 658089 D hypothetical protein 657994..658089 Brucella suis 1330 1165122 NP_699863.1 CDS BRA0681 NC_004311.2 658101 661697 D similar to GP:15139898; identified by sequence similarity; hydantoinase/oxoprolinase 658101..661697 Brucella suis 1330 1165123 NP_699864.1 CDS fliY NC_004311.2 661983 662756 D similar to GP:15076300; identified by sequence similarity; amino acid ABC transporter substrate-binding protein 661983..662756 Brucella suis 1330 1165124 NP_699865.1 CDS BRA0683 NC_004311.2 662936 663616 D similar to GP:15076302; identified by sequence similarity; amino acid ABC transporter permease 662936..663616 Brucella suis 1330 1165125 NP_699866.1 CDS BRA0684 NC_004311.2 663613 664374 D similar to GP:15076303, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, PID:458555, GB:J00128, GB:M58569, GB:M64982, GB:J00127, GB:K02272, GB:M26878, SP:P02671, GB:S82092, PID:182407, PID:182424, PID:182426, PID:182428, PID:458554, and PID:458555; identified by sequence similarity; amino acid ABC transporter ATP-binding protein 663613..664374 Brucella suis 1330 1165126 NP_699867.1 CDS BRA0685 NC_004311.2 664616 666112 D identified by match to TIGR protein family HMM TIGR01622; Ppx/GppA phosphatase 664616..666112 Brucella suis 1330 1165127 NP_699868.1 CDS BRA0686 NC_004311.2 666189 666836 D identified by match to TIGR protein family HMM TIGR00438; ribosomal RNA large subunit methyltransferase J 666189..666836 Brucella suis 1330 1165128 NP_699869.1 CDS BRA0687 NC_004311.2 667035 668444 R identified by match to TIGR protein family HMM TIGR00897; Bcr/CflA subfamily drug resistance transporter complement(667035..668444) Brucella suis 1330 1165129 NP_699870.1 CDS BRA0688 NC_004311.2 668488 668772 R hypothetical protein complement(668488..668772) Brucella suis 1330 1165130 NP_699871.1 CDS BRA0689 NC_004311.2 668784 668885 D hypothetical protein 668784..668885 Brucella suis 1330 1165131 NP_699872.1 CDS BRA0691 NC_004311.2 670139 671020 R similar to GP:15076325; identified by sequence similarity; sugar ABC transporter permease complement(670139..671020) Brucella suis 1330 1165133 NP_699873.1 CDS BRA0692 NC_004311.2 671017 672066 R similar to GP:13936895, and GP:2828821; identified by sequence similarity; sugar ABC transporter permease complement(671017..672066) Brucella suis 1330 1165134 NP_699874.1 CDS BRA0693 NC_004311.2 672174 673439 R similar to GP:9964068, GB:L19113, SP:P39143, PID:437318, and GB:AL009126; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein complement(672174..673439) Brucella suis 1330 1165135 NP_699875.1 CDS BRA0694 NC_004311.2 673934 674182 R hypothetical protein complement(673934..674182) Brucella suis 1330 1165136 NP_699876.1 CDS ribH NC_004311.2 674326 674802 D RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; riboflavin synthase subunit beta 674326..674802 Brucella suis 1330 1165137 NP_699877.1 CDS BRA0697 NC_004311.2 675721 676065 D identified by match to TIGR protein family HMM TIGR01244; hypothetical protein 675721..676065 Brucella suis 1330 1165139 NP_699878.1 CDS BRA0698 NC_004311.2 676032 676268 R hypothetical protein complement(676032..676268) Brucella suis 1330 1165140 NP_699879.1 CDS BRA0699 NC_004311.2 676714 678483 R similar to GP:15155325, and SP:P71338; identified by sequence similarity; iron ABC transporter permease complement(676714..678483) Brucella suis 1330 1165141 NP_699880.1 CDS BRA0700 NC_004311.2 678504 679520 R similar to GP:15155324, and SP:P35755; identified by sequence similarity; iron ABC transporter substrate-binding protein complement(678504..679520) Brucella suis 1330 1165142 NP_699881.1 CDS BRA0701 NC_004311.2 679646 680749 R similar to GP:15155323; identified by sequence similarity; iron ABC transporter ATP-binding protein complement(679646..680749) Brucella suis 1330 1165143 NP_699882.1 CDS BRA0702 NC_004311.2 680986 682314 D similar to GP:15075956; identified by sequence similarity; D-amino acid oxidase 680986..682314 Brucella suis 1330 1165144 NP_699883.1 CDS sodC NC_004311.2 682572 683093 R similar to GB:M92844, GB:M63625, GB:M92843, SP:P26651, PID:183443, PID:183445, PID:340013, SP:P20922, and PID:581487; identified by sequence similarity; superoxide dismutase, Cu-Zn complement(682572..683093) Brucella suis 1330 1165145 NP_699884.1 CDS BRA0704 NC_004311.2 683369 684973 R laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification; multicopper oxidase complement(683369..684973) Brucella suis 1330 1165146 NP_699885.1 CDS BRA0705 NC_004311.2 685033 685428 R hypothetical protein complement(685033..685428) Brucella suis 1330 1165147 NP_699886.1 CDS BRA0706 NC_004311.2 685682 686962 D similar to GP:15075195; identified by sequence similarity; major facilitator family transporter 685682..686962 Brucella suis 1330 1165148 NP_699887.1 CDS ahpD NC_004311.2 687040 687567 R similar to GP:12620484; identified by sequence similarity; alkyl hydroperoxide reductase complement(687040..687567) Brucella suis 1330 1165149 NP_699888.1 CDS ahpC NC_004311.2 687647 688201 R similar to GP:12620485, and GP:12620485; identified by sequence similarity; alkyl hydroperoxide reductase complement(687647..688201) Brucella suis 1330 1165150 NP_699889.1 CDS BRA0709 NC_004311.2 688327 689232 D similar to GB:L04510, SP:P36406, and PID:292070; identified by sequence similarity; transcriptional regulator OxyR 688327..689232 Brucella suis 1330 1165151 NP_699890.1 CDS BRA0710 NC_004311.2 689262 690329 R similar to GP:15159268, SP:P07002, GB:X66086, PID:42457, GB:U00096, PID:1742636, PID:1742642, PID:1742653, and PID:1787886; identified by sequence similarity; hypothetical protein complement(689262..690329) Brucella suis 1330 1165152 NP_699891.1 CDS idhA NC_004311.2 690427 691419 R similar to GP:15159273, and SP:O68965; identified by sequence similarity; myo-inositol 2-dehydrogenase complement(690427..691419) Brucella suis 1330 1165153 NP_699892.1 CDS BRA0712 NC_004311.2 691653 692423 D similar to GP:15158705; identified by sequence similarity; SIS domain-containing protein 691653..692423 Brucella suis 1330 1165154 NP_699893.1 CDS iolD NC_004311.2 694451 696274 D similar to GP:15158707, and GP:7209271; identified by sequence similarity; TPP-requiring enzyme IolD 694451..696274 Brucella suis 1330 1165156 NP_699894.1 CDS iolE NC_004311.2 696278 697180 D similar to GP:15158708; identified by sequence similarity; hypothetical protein 696278..697180 Brucella suis 1330 1165157 NP_699895.1 CDS BRA0717 NC_004311.2 698026 698826 R similar to GP:15140221, GB:X56692, GB:M11725, GB:M11880, GB:M35163, SP:P02741, PID:181066, PID:181068, PID:181073, and PID:30213; identified by sequence similarity; inositol monophosphatase complement(698026..698826) Brucella suis 1330 1165159 NP_699896.1 CDS BRA0718 NC_004311.2 698847 699908 R similar to GP:15140222; identified by sequence similarity; ABC transporter ATP-binding protein complement(698847..699908) Brucella suis 1330 1165160 NP_699897.1 CDS BRA0719 NC_004311.2 699905 702130 R similar to GP:15158391, and GP:17743296; identified by sequence similarity; ABC transporter permease complement(699905..702130) Brucella suis 1330 1165161 NP_699898.1 CDS BRA0720 NC_004311.2 702265 703290 R similar to GP:15140224; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein complement(702265..703290) Brucella suis 1330 1165162 NP_699899.1 CDS BRA0721 NC_004311.2 703274 703417 D hypothetical protein 703274..703417 Brucella suis 1330 1165163 YP_002519392.1 CDS putA NC_004311.2 703520 707203 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the protein from Pseudomonas does not have this domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(703520..707203) Brucella suis 1330 1165164 NP_699900.1 CDS BRA0723 NC_004311.2 707366 707860 D similar to GB:M64551, SP:P26514, PID:153527, GB:M64551, SP:P26514, and PID:153527; identified by sequence similarity; proline dehydrogenase 707366..707860 Brucella suis 1330 1165165 NP_699901.1 CDS BRA0724 NC_004311.2 707842 707955 R hypothetical protein complement(707842..707955) Brucella suis 1330 1165166 NP_699902.1 CDS gcvP NC_004311.2 708891 711689 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; glycine dehydrogenase complement(708891..711689) Brucella suis 1330 1165167 NP_699903.1 CDS gcvH NC_004311.2 711694 712062 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system protein H complement(711694..712062) Brucella suis 1330 1165168 NP_699904.1 CDS gcvT NC_004311.2 712068 713171 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; glycine cleavage system aminomethyltransferase T complement(712068..713171) Brucella suis 1330 1165169 NP_699905.1 CDS BRA0728 NC_004311.2 713813 713971 D similar to GP:15074478; identified by sequence similarity; hypothetical protein 713813..713971 Brucella suis 1330 1165170 NP_699906.1 CDS BRA0729 NC_004311.2 714153 715382 R identified by match to TIGR protein family HMM TIGR01424; pyridine nucleotide-disulfide oxidoreductase complement(714153..715382) Brucella suis 1330 1165171 NP_699907.1 CDS BRA0730 NC_004311.2 715494 716438 R similar to GP:15024826; identified by sequence similarity; transcriptional regulator complement(715494..716438) Brucella suis 1330 1165172 NP_699908.1 CDS BRA0731 NC_004311.2 716465 717262 D hypothetical protein 716465..717262 Brucella suis 1330 1165173 NP_699909.1 CDS BRA0732 NC_004311.2 717326 718693 D identified by match to PFAM protein family HMM PF00120; glutamine synthetase 717326..718693 Brucella suis 1330 1165174 NP_699910.1 CDS BRA0733 NC_004311.2 718687 718803 R hypothetical protein complement(718687..718803) Brucella suis 1330 1165175 NP_699911.1 CDS BRA0734 NC_004311.2 718794 719963 D similar to GB:M33308, SP:P18206, PID:292902, and PID:340237; identified by sequence similarity; alcohol dehydrogenase 718794..719963 Brucella suis 1330 1165176 NP_699912.1 CDS BRA0735 NC_004311.2 720145 720588 D similar to GP:3236220, and GP:3236220; identified by sequence similarity; hypothetical protein 720145..720588 Brucella suis 1330 1165177 NP_699913.1 CDS BRA0736 NC_004311.2 720718 720915 D hypothetical protein 720718..720915 Brucella suis 1330 1165178 NP_699914.1 CDS BRA0737 NC_004311.2 721051 721896 D similar to GP:15075527; identified by sequence similarity; hypothetical protein 721051..721896 Brucella suis 1330 1165179 NP_699915.1 CDS BRA0738 NC_004311.2 721942 722808 R similar to GP:19747452; identified by sequence similarity; glycine betaine/L-proline ABC transporter periplasmic glycine betaine-binding protein complement(721942..722808) Brucella suis 1330 1165180 NP_699916.1 CDS BRA0739 NC_004311.2 722862 723767 R similar to GP:6119662, and GP:6119854; identified by sequence similarity; glycine betaine/L-proline ABC transporter permease complement(722862..723767) Brucella suis 1330 1165181 NP_699917.1 CDS BRA0740 NC_004311.2 723830 724996 R similar to SP:P46920, GB:M88282, SP:P40200, and PID:338672; identified by sequence similarity; glycine betaine/L-proline ABC transporter ATP-binding protein complement(723830..724996) Brucella suis 1330 1165182 NP_699918.1 CDS BRA0741 NC_004311.2 725209 725394 R hypothetical protein complement(725209..725394) Brucella suis 1330 1165183 NP_699919.1 CDS BRA0742 NC_004311.2 725557 726030 R hypothetical protein complement(725557..726030) Brucella suis 1330 1165184 NP_699920.1 CDS BRA0743 NC_004311.2 726044 727111 R similar to GP:15140598; identified by sequence similarity; amino acid processing-like protein complement(726044..727111) Brucella suis 1330 1165185 NP_699921.1 CDS BRA0744 NC_004311.2 727116 728033 R identified by match to TIGR protein family HMM TIGR00441; RpiR family transcriptional regulator complement(727116..728033) Brucella suis 1330 1165186 NP_699922.1 CDS BRA0745 NC_004311.2 728005 729057 R similar to SP:P55604; identified by sequence similarity; sugar ABC transporter ATP-binding protein complement(728005..729057) Brucella suis 1330 1165187 NP_699923.1 CDS BRA0746 NC_004311.2 729062 729835 R similar to GP:14024269; identified by sequence similarity; short chain dehydrogenase/reductase oxidoreductase complement(729062..729835) Brucella suis 1330 1165188 NP_699924.1 CDS BRA0747 NC_004311.2 729852 729962 D hypothetical protein 729852..729962 Brucella suis 1330 1165189 NP_699925.1 CDS BRA0748 NC_004311.2 730015 731250 D similar to GP:2828820; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein 730015..731250 Brucella suis 1330 1165190 NP_699926.1 CDS BRA0749 NC_004311.2 731323 732192 D similar to GP:2828821; identified by sequence similarity; sugar ABC transporter permease 731323..732192 Brucella suis 1330 1165191 NP_699927.1 CDS BRA0750 NC_004311.2 732189 733016 D identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter permease 732189..733016 Brucella suis 1330 1165192 NP_699928.1 CDS BRA0751 NC_004311.2 733029 733400 D identified by match to TIGR protein family HMM TIGR00004; endoribonuclease L-PSP 733029..733400 Brucella suis 1330 1165193 NP_699929.1 CDS BRA0752 NC_004311.2 733427 734896 D hypothetical protein 733427..734896 Brucella suis 1330 1165194 NP_699930.1 CDS BRA0753 NC_004311.2 735057 735299 R hypothetical protein complement(735057..735299) Brucella suis 1330 1165195 NP_699931.1 CDS BRA0754 NC_004311.2 735357 736154 R similar to GP:15139930, and GP:8217385; identified by sequence similarity; iron ABC transporter ATP-binding protein complement(735357..736154) Brucella suis 1330 1165196 NP_699932.1 CDS BRA0755 NC_004311.2 736151 737194 R similar to GP:15139929; identified by sequence similarity; iron ABC transporter permease complement(736151..737194) Brucella suis 1330 1165197 NP_699933.1 CDS BRA0756 NC_004311.2 737191 738225 R similar to GP:15159961, and GP:8546929; identified by sequence similarity; iron ABC transporter substrate-binding protein complement(737191..738225) Brucella suis 1330 1165198 NP_699934.1 CDS BRA0757 NC_004311.2 738182 738598 R hypothetical protein complement(738182..738598) Brucella suis 1330 1165199 NP_699935.1 CDS BRA0758 NC_004311.2 738776 739642 R similar to GP:15162366; identified by sequence similarity; HlyD family secretion protein complement(738776..739642) Brucella suis 1330 1165200 NP_699936.1 CDS BRA0759 NC_004311.2 739639 739848 R similar to GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, PID:567108, GB:M23114, GB:M23116, GB:M23278, GB:M23115, SP:P16614, SP:P16615, PID:306850, PID:306851, and PID:567108; identified by sequence similarity; hypothetical protein complement(739639..739848) Brucella suis 1330 1165201 NP_699937.1 CDS BRA0760 NC_004311.2 739875 741971 R similar to GP:15162367; identified by sequence similarity; hypothetical protein complement(739875..741971) Brucella suis 1330 1165202 NP_699938.1 CDS BRA0761 NC_004311.2 742014 742451 R similar to GP:15074064; identified by sequence similarity; MarR family transcriptional regulator complement(742014..742451) Brucella suis 1330 1165203 NP_699939.2 CDS BRA0762 NC_004311.2 742701 743447 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 742701..743447 Brucella suis 1330 1165204 NP_699940.1 CDS BRA0763 NC_004311.2 743547 744920 D identified by match to TIGR protein family HMM TIGR01436; glutamate--cysteine ligase 743547..744920 Brucella suis 1330 1165205 NP_699941.1 CDS xseA NC_004311.2 744986 746521 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit complement(744986..746521) Brucella suis 1330 1165206 NP_699942.1 CDS BRA0765 NC_004311.2 746590 747558 R identified by match to PFAM protein family HMM PF00126; LysR family transcriptional regulator complement(746590..747558) Brucella suis 1330 1165207 NP_699943.1 CDS BRA0766 NC_004311.2 747725 748027 D hypothetical protein 747725..748027 Brucella suis 1330 1165208 NP_699944.1 CDS BRA0767 NC_004311.2 748021 748275 D hypothetical protein 748021..748275 Brucella suis 1330 1165209 NP_699945.1 CDS BRA0768 NC_004311.2 748279 749709 D identified by match to PFAM protein family HMM PF00120; glutamine synthetase 748279..749709 Brucella suis 1330 1165210 NP_699946.1 CDS BRA0769 NC_004311.2 749761 750123 D crystal structure of protein from Xanthomonas shows pentameric toroidal structure; physiological function is unknown; hypothetical protein 749761..750123 Brucella suis 1330 1165211 NP_699947.1 CDS BRA0770 NC_004311.2 750177 751463 D similar to SP:Q9Z3S3; identified by sequence similarity; D-amino acid oxidase 750177..751463 Brucella suis 1330 1165212 NP_699948.1 CDS BRA0771 NC_004311.2 751474 751890 R identified by match to PFAM protein family HMM PF01047; MarR family transcriptional regulator complement(751474..751890) Brucella suis 1330 1165213 NP_699949.1 CDS BRA0772 NC_004311.2 752200 753000 R hypothetical protein complement(752200..753000) Brucella suis 1330 1165214 NP_699950.1 CDS BRA0773 NC_004311.2 753259 753723 R identified by match to PFAM protein family HMM PF01037; AsnC family transcriptional regulator complement(753259..753723) Brucella suis 1330 1165215 NP_699951.1 CDS BRA0774 NC_004311.2 754099 754839 D similar to SP:O07942; identified by sequence similarity; AzlC family protein 754099..754839 Brucella suis 1330 1165216 NP_699952.1 CDS BRA0775 NC_004311.2 754836 755135 D hypothetical protein 754836..755135 Brucella suis 1330 1165217 NP_699953.1 CDS fabG NC_004311.2 756710 757459 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(756710..757459) Brucella suis 1330 1165219 NP_699954.1 CDS zwf NC_004311.2 757730 759205 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 757730..759205 Brucella suis 1330 1165220 NP_699955.1 CDS pgl NC_004311.2 759334 760032 D catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone; 6-phosphogluconolactonase 759334..760032 Brucella suis 1330 1165221 NP_699956.1 CDS folD NC_004311.2 761984 762883 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase complement(761984..762883) Brucella suis 1330 1165223 NP_699957.1 CDS proC NC_004311.2 763204 764019 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 763204..764019 Brucella suis 1330 1165224 NP_699958.1 CDS BRA0784 NC_004311.2 765607 766437 R similar to SP:Q53192; identified by sequence similarity; peptide ABC transporter permease complement(765607..766437) Brucella suis 1330 1165226 NP_699959.1 CDS BRA0785 NC_004311.2 766434 767432 R similar to SP:Q53191; identified by sequence similarity; peptide ABC transporter permease complement(766434..767432) Brucella suis 1330 1165227 NP_699960.1 CDS BRA0786 NC_004311.2 767450 769063 R similar to GP:17741829; identified by sequence similarity; peptide ABC transporter substrate-binding protein complement(767450..769063) Brucella suis 1330 1165228 NP_699961.1 CDS BRA0787 NC_004311.2 769418 769762 D similar to GP:15141400, and GP:15141400; identified by sequence similarity; hypothetical protein 769418..769762 Brucella suis 1330 1165229 NP_699962.1 CDS BRA0788 NC_004311.2 769911 770570 D similar to GP:14277936; identified by sequence similarity; carbonic anhydrase 769911..770570 Brucella suis 1330 1165230 NP_699963.1 CDS BRA0789 NC_004311.2 770632 771042 R identified by match to PFAM protein family HMM PF03794; hypothetical protein complement(770632..771042) Brucella suis 1330 1165231 NP_699964.1 CDS lysK NC_004311.2 771237 772892 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 771237..772892 Brucella suis 1330 1165232 NP_699965.1 CDS BRA0791 NC_004311.2 772980 773939 R similar to GP:14025443; identified by sequence similarity; hypothetical protein complement(772980..773939) Brucella suis 1330 1165233 NP_699966.1 CDS BRA0792 NC_004311.2 773940 774596 R similar to GP:15155410; identified by sequence similarity; S24 family peptidase complement(773940..774596) Brucella suis 1330 1165234 NP_699967.1 CDS fadB NC_004311.2 774834 777050 R similar to GB:X65488, SP:Q00839, PID:32358, and PID:532037; identified by sequence similarity; fatty oxidation complex subunit alpha complement(774834..777050) Brucella suis 1330 1165235 NP_699968.1 CDS BRA0794 NC_004311.2 777066 778274 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(777066..778274) Brucella suis 1330 1165236 NP_699969.1 CDS BRA0795 NC_004311.2 778339 780132 R identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase complement(778339..780132) Brucella suis 1330 1165237 NP_699970.1 CDS BRA0796 NC_004311.2 780107 780301 R hypothetical protein complement(780107..780301) Brucella suis 1330 1165238 NP_699971.1 CDS BRA0797 NC_004311.2 780298 780576 R hypothetical protein complement(780298..780576) Brucella suis 1330 1165239 NP_699972.1 CDS BRA0799 NC_004311.2 782079 783245 D identified by match to PFAM protein family HMM PF02771; acyl-CoA dehydrogenase 782079..783245 Brucella suis 1330 1165241 NP_699973.1 CDS nikE NC_004311.2 783378 784178 R with NikABCD is involved with nickel transport into the cell; nickel transporter ATP-binding protein NikE complement(783378..784178) Brucella suis 1330 1165242 NP_699974.1 CDS nikD NC_004311.2 784175 784963 R with NikABCE is involved in nickel transport into the cell; nickel transporter ATP-binding protein NikD complement(784175..784963) Brucella suis 1330 1165243 NP_699975.1 CDS nikC NC_004311.2 784960 785832 R with NikABDE is involved in nickel transport into the cell; nickel transporter permease NikC complement(784960..785832) Brucella suis 1330 1165244 NP_699976.1 CDS nikB NC_004311.2 785829 786773 R with NikACDE is involved in nickel transport into the cell; nickel transporter permease NikB complement(785829..786773) Brucella suis 1330 1165245 NP_699977.1 CDS BRA0804 NC_004311.2 786775 788355 R similar to GP:12331180, and GP:12331180; identified by sequence similarity; nickel ABC transporter nickel-binding protein complement(786775..788355) Brucella suis 1330 1165246 NP_699978.1 CDS BRA0805 NC_004311.2 788622 789020 D Inhibits transcription at high concentrations of nickel; nickel responsive regulator 788622..789020 Brucella suis 1330 1165247 NP_699979.1 CDS BRA0806 NC_004311.2 789031 790575 R similar to GP:15158051, GB:M25393, SP:P17706, and PID:804750; identified by sequence similarity; UxaA family hydrolase complement(789031..790575) Brucella suis 1330 1165248 NP_699980.1 CDS BRA0807 NC_004311.2 790653 791495 R similar to GB:U12770, GB:U12774, GB:U12775, GB:L37019, SP:P42127, PID:540073, and PID:608648; identified by sequence similarity; ABC transporter permease complement(790653..791495) Brucella suis 1330 1165249 NP_699981.1 CDS BRA0809 NC_004311.2 792403 793455 R similar to GP:9501758; identified by sequence similarity; ABC transporter ATP-binding protein complement(792403..793455) Brucella suis 1330 1165251 NP_699982.1 CDS BRA0810 NC_004311.2 793533 794714 R identified by match to TIGR protein family HMM TIGR01409; ABC transporter periplasmic substrate-binding protein complement(793533..794714) Brucella suis 1330 1165252 NP_699983.1 CDS BRA0812 NC_004311.2 796378 797778 R catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; glucuronate isomerase complement(796378..797778) Brucella suis 1330 1165254 NP_699984.1 CDS BRA0813 NC_004311.2 798107 798880 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 798107..798880 Brucella suis 1330 1165255 NP_699985.1 CDS uxuA NC_004311.2 798941 800146 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 798941..800146 Brucella suis 1330 1165256 NP_699986.1 CDS BRA0816 NC_004311.2 803432 804418 R identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein complement(803432..804418) Brucella suis 1330 1165258 NP_699987.1 CDS BRA0817 NC_004311.2 804875 805276 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 804875..805276 Brucella suis 1330 1165259 NP_699988.1 CDS BRA0818 NC_004311.2 805273 805686 D may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB 805273..805686 Brucella suis 1330 1165260 NP_699989.1 CDS BRA0819 NC_004311.2 805702 806061 D identified by match to PFAM protein family HMM PF02641; hypothetical protein 805702..806061 Brucella suis 1330 1165261 NP_699990.1 CDS BRA0820 NC_004311.2 806116 806511 R identified by match to PFAM protein family HMM PF00376; MerR family transcriptional regulator complement(806116..806511) Brucella suis 1330 1165262 NP_699991.1 CDS BRA0821 NC_004311.2 806805 806942 R hypothetical protein complement(806805..806942) Brucella suis 1330 1165263 NP_699992.1 CDS BRA0822 NC_004311.2 806941 809682 D identified by match to PFAM protein family HMM PF04012; peptidoglycan-binding protein 806941..809682 Brucella suis 1330 1165264 NP_699993.1 CDS BRA0823 NC_004311.2 809919 810869 D similar to GP:14025434, and GP:14025434; identified by sequence similarity; hypothetical protein 809919..810869 Brucella suis 1330 1165265 NP_699994.1 CDS BRA0824 NC_004311.2 810904 811695 D hypothetical protein 810904..811695 Brucella suis 1330 1165266 NP_699995.1 CDS BRA0825 NC_004311.2 811793 812509 R identified by match to TIGR protein family HMM TIGR00024; hypothetical protein complement(811793..812509) Brucella suis 1330 1165267 NP_699996.1 CDS BRA0826 NC_004311.2 812506 815061 R similar to GP:14025425; identified by sequence similarity; DEAD-box ATP dependent DNA helicase complement(812506..815061) Brucella suis 1330 1165268 NP_699997.1 CDS BRA0827 NC_004311.2 815071 815217 R hypothetical protein complement(815071..815217) Brucella suis 1330 1165269 NP_699998.1 CDS BRA0828 NC_004311.2 815313 816335 R similar to GP:15073435; identified by sequence similarity; hypothetical protein complement(815313..816335) Brucella suis 1330 1165270 NP_699999.1 CDS BRA0829 NC_004311.2 816313 816450 D hypothetical protein 816313..816450 Brucella suis 1330 1165271 NP_700000.1 CDS BRA0830 NC_004311.2 816534 816695 R hypothetical protein complement(816534..816695) Brucella suis 1330 1165272 NP_700001.1 CDS BRA0831 NC_004311.2 816842 817810 D similar to GP:15155334, and GP:15073434; identified by sequence similarity; 2-nitropropane dioxygenase 816842..817810 Brucella suis 1330 1165273 NP_700002.1 CDS BRA0832 NC_004311.2 817869 818006 D hypothetical protein 817869..818006 Brucella suis 1330 1165274 NP_700003.1 CDS BRA0833 NC_004311.2 818865 819587 D hypothetical protein 818865..819587 Brucella suis 1330 1165276 NP_700004.1 CDS BRA0834 NC_004311.2 819594 820094 R hypothetical protein complement(819594..820094) Brucella suis 1330 1165277 NP_700005.1 CDS BRA0835 NC_004311.2 820233 820349 D hypothetical protein 820233..820349 Brucella suis 1330 1165278 NP_700006.1 CDS BRA0836 NC_004311.2 820645 820842 R similar to GP:7630140; identified by sequence similarity; hypothetical protein complement(820645..820842) Brucella suis 1330 1165279 NP_700007.1 CDS BRA0837 NC_004311.2 820911 821066 D hypothetical protein 820911..821066 Brucella suis 1330 1165280 NP_700008.1 CDS BRA0838 NC_004311.2 821860 822000 R hypothetical protein complement(821860..822000) Brucella suis 1330 1165281 NP_700009.1 CDS BRA0839 NC_004311.2 822161 822793 D identified by match to PFAM protein family HMM PF01420; hypothetical protein 822161..822793 Brucella suis 1330 1165282 NP_700010.1 CDS hsdM NC_004311.2 822801 824327 D identified by match to PFAM protein family HMM PF01170; type I restriction-modification system, M subunit 822801..824327 Brucella suis 1330 1165283 NP_700011.1 CDS hsdS NC_004311.2 824317 825540 D identified by match to PFAM protein family HMM PF03809; type I restriction-modification system, S subunit 824317..825540 Brucella suis 1330 1165284 NP_700012.1 CDS hsdR NC_004311.2 825603 828506 D identified by match to PFAM protein family HMM PF03726; type I restriction-modification enzyme, R subunit 825603..828506 Brucella suis 1330 1165285 NP_700013.1 CDS BRA0843 NC_004311.2 828503 829243 D identified by match to PFAM protein family HMM PF01863; hypothetical protein 828503..829243 Brucella suis 1330 1165286 NP_700014.1 CDS BRA0844 NC_004311.2 829251 830180 D similar to GP:6900910, GB:J00153, GB:V00491, GB:V00492, GB:J00157, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, PID:537333, GB:J00153, GB:V00516, GB:V00493, GB:V00488, GB:V00489, GB:M24793, GB:M22814, SP:P01922, PID:1335076, PID:1340147, PID:1340148, PID:1817577, PID:1817578, PID:183801, PID:183805, PID:28547, PID:28558, PID:386764, PID:386765, and PID:537333; identified by sequence similarity; hypothetical protein 829251..830180 Brucella suis 1330 1165287 NP_700015.1 CDS BRA0846 NC_004311.2 832598 832909 D similar to GB:X07282, SP:P10826, PID:184477, PID:32026, PID:35883, GB:D38554, PID:1354931, and PID:559705; identified by sequence similarity; IS711, transposase orfA 832598..832909 Brucella suis 1330 1165289 NP_700016.1 CDS BRA0847 NC_004311.2 832941 833333 D similar to PIR:PN0685, GB:X07282, SP:P10826, PID:184477, PID:32026, and PID:35883; identified by sequence similarity; IS711, transposase orfB 832941..833333 Brucella suis 1330 1165290 NP_700017.1 CDS BRA0848 NC_004311.2 833347 833481 R hypothetical protein complement(833347..833481) Brucella suis 1330 1165291 NP_700018.1 CDS BRA0849 NC_004311.2 833743 834189 D hypothetical protein 833743..834189 Brucella suis 1330 1165292 NP_700019.1 CDS BRA0850 NC_004311.2 834300 835985 D identified by match to PFAM protein family HMM PF03788; hypothetical protein 834300..835985 Brucella suis 1330 1165293 NP_700020.1 CDS BRA0851 NC_004311.2 836149 837603 R identified by match to PFAM protein family HMM PF03819; aminotransferase complement(836149..837603) Brucella suis 1330 1165294 NP_700021.1 CDS BRA0852 NC_004311.2 837614 838624 R identified by match to TIGR protein family HMM TIGR01472; epimerase complement(837614..838624) Brucella suis 1330 1165295 NP_700022.1 CDS BRA0853 NC_004311.2 838673 839092 R identified by match to PFAM protein family HMM PF00893; hypothetical protein complement(838673..839092) Brucella suis 1330 1165296 NP_700023.1 CDS BRA0855 NC_004311.2 840460 841899 R identified by match to TIGR protein family HMM TIGR01668; hypothetical protein complement(840460..841899) Brucella suis 1330 1165298 NP_700024.1 CDS BRA0856 NC_004311.2 842135 842230 D hypothetical protein 842135..842230 Brucella suis 1330 1165299 NP_700025.1 CDS BRA0857 NC_004311.2 842522 843343 R identified by match to PFAM protein family HMM PF00455; DeoR family transcriptional regulator complement(842522..843343) Brucella suis 1330 1165300 NP_700026.1 CDS rbsB-2 NC_004311.2 843551 844498 R ribose ABC transporter periplasmic D-ribose-binding protein complement(843551..844498) Brucella suis 1330 1165301 NP_700027.1 CDS rbsC-3 NC_004311.2 844665 845705 R similar to GP:15140211; identified by sequence similarity; ribose ABC transporter permease complement(844665..845705) Brucella suis 1330 1165302 NP_700028.1 CDS rbsA-3 NC_004311.2 845729 847273 R identified by match to TIGR protein family HMM TIGR00972; ribose ABC transporter ATP-binding protein complement(845729..847273) Brucella suis 1330 1165303 NP_700029.1 CDS BRA0861 NC_004311.2 847270 847926 R similar to GP:15140209, and GP:15140209; identified by sequence similarity; hypothetical protein complement(847270..847926) Brucella suis 1330 1165304 NP_700030.1 CDS BRA0862 NC_004311.2 847906 848073 D hypothetical protein 847906..848073 Brucella suis 1330 1165305 NP_700031.1 CDS BRA0863 NC_004311.2 848525 848677 D hypothetical protein 848525..848677 Brucella suis 1330 1165306 NP_700032.1 CDS eryA NC_004311.2 848670 850223 D similar to GP:4204896, and GP:4204896; identified by sequence similarity; erythritol kinase 848670..850223 Brucella suis 1330 1165307 NP_700033.1 CDS eryB NC_004311.2 850236 851744 D in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane; glycerol-3-phosphate dehydrogenase 850236..851744 Brucella suis 1330 1165308 NP_700034.1 CDS eryC NC_004311.2 851752 852684 D similar to GP:4204898, and GP:4204898; identified by sequence similarity; D-erythrulose-1-phosphate dehydrogenase 851752..852684 Brucella suis 1330 1165309 NP_700035.1 CDS eryD NC_004311.2 852712 853662 D similar to GP:4204899, and GP:4204899; identified by sequence similarity; erythritol transcriptional regulator 852712..853662 Brucella suis 1330 1165310 NP_700036.1 CDS BRA0868 NC_004311.2 853750 854514 D similar to GP:4204900; identified by sequence similarity; DeoR family transcriptional regulator 853750..854514 Brucella suis 1330 1165311 NP_700037.1 CDS tpiA NC_004311.2 854527 855297 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 854527..855297 Brucella suis 1330 1165312 NP_700038.1 CDS BRA0870 NC_004311.2 855309 855764 D catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; ribose-5-phosphate isomerase B 855309..855764 Brucella suis 1330 1165313 NP_700039.1 CDS fbaA NC_004311.2 855831 856895 R class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis; fructose-1,6-bisphosphate aldolase complement(855831..856895) Brucella suis 1330 1165314 NP_700040.1 CDS fbp NC_004311.2 856926 857948 R catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate; fructose-1,6-bisphosphatase complement(856926..857948) Brucella suis 1330 1165315 NP_700041.1 CDS BRA0873 NC_004311.2 857945 858184 R hypothetical protein complement(857945..858184) Brucella suis 1330 1165316 NP_700042.1 CDS BRA0874 NC_004311.2 858382 859071 R similar to GP:15073394, and GP:15073394; identified by sequence similarity; hypothetical protein complement(858382..859071) Brucella suis 1330 1165317 NP_700043.1 CDS BRA0875 NC_004311.2 859121 860947 R similar to GP:15076115; identified by sequence similarity; GTP-binding protein TypA complement(859121..860947) Brucella suis 1330 1165318 NP_700044.1 CDS mgtE NC_004311.2 861190 862587 R similar to GP:17134323; identified by sequence similarity; magnesium transporter complement(861190..862587) Brucella suis 1330 1165319 NP_700045.1 CDS BRA0877 NC_004311.2 862654 862818 R hypothetical protein complement(862654..862818) Brucella suis 1330 1165320 NP_700046.1 CDS dcp NC_004311.2 862913 864961 D similar to SP:P24171; identified by sequence similarity; peptidyl-dipeptidase Dcp 862913..864961 Brucella suis 1330 1165321 NP_700047.1 CDS BRA0879 NC_004311.2 864990 865343 R identified by match to PFAM protein family HMM PF00903; glyoxalase complement(864990..865343) Brucella suis 1330 1165322 NP_700048.1 CDS BRA0880 NC_004311.2 865343 865549 R similar to GP:15076201, and GP:15076201; identified by sequence similarity; hypothetical protein complement(865343..865549) Brucella suis 1330 1165323 NP_700049.1 CDS BRA0882 NC_004311.2 866595 866801 D hypothetical protein 866595..866801 Brucella suis 1330 1165325 NP_700050.1 CDS leuD NC_004311.2 866866 867471 D catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 866866..867471 Brucella suis 1330 1165326 NP_700051.1 CDS BRA0884 NC_004311.2 867557 867979 D similar to GP:15076200; identified by sequence similarity; hypothetical protein 867557..867979 Brucella suis 1330 1165327 NP_700052.1 CDS ohr NC_004311.2 868030 868452 R similar to GP:15073893, and SP:O68390; identified by sequence similarity; organic hydroperoxide resistance protein complement(868030..868452) Brucella suis 1330 1165328 NP_700053.1 CDS BRA0886 NC_004311.2 868658 869113 D similar to GP:14456720; identified by sequence similarity; MarR family transcriptional regulator 868658..869113 Brucella suis 1330 1165329 NP_700054.1 CDS asd NC_004311.2 869177 870211 R catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase complement(869177..870211) Brucella suis 1330 1165330 NP_700055.1 CDS BRA0888 NC_004311.2 870734 872632 D similar to GP:15157678; identified by sequence similarity; major facilitator family transporter 870734..872632 Brucella suis 1330 1165331 NP_700056.1 CDS BRA0889 NC_004311.2 872690 873742 R similar to GP:15073366; identified by sequence similarity; ada regulatory protein complement(872690..873742) Brucella suis 1330 1165332 NP_700057.1 CDS leuB NC_004311.2 873883 874995 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(873883..874995) Brucella suis 1330 1165333 NP_700058.1 CDS BRA0891 NC_004311.2 875295 875489 R identified by match to PFAM protein family HMM PF03966; hypothetical protein complement(875295..875489) Brucella suis 1330 1165334 NP_700059.1 CDS BRA0892 NC_004311.2 875666 876370 R similar to GP:14024485; identified by sequence similarity; ATP-dependent protease La complement(875666..876370) Brucella suis 1330 1165335 NP_700060.1 CDS trx-2 NC_004311.2 876434 877408 R identified by match to PFAM protein family HMM PF03745; thioredoxin complement(876434..877408) Brucella suis 1330 1165336 NP_700061.1 CDS BRA0894 NC_004311.2 877656 878198 R hypothetical protein complement(877656..878198) Brucella suis 1330 1165337 NP_700062.1 CDS BRA0895 NC_004311.2 878206 878397 R hypothetical protein complement(878206..878397) Brucella suis 1330 1165338 NP_700063.1 CDS BRA0896 NC_004311.2 878613 879122 R hypothetical protein complement(878613..879122) Brucella suis 1330 1165340 NP_700064.1 CDS BRA0897 NC_004311.2 878874 879029 D hypothetical protein 878874..879029 Brucella suis 1330 1165341 NP_700065.1 CDS BRA0898 NC_004311.2 879194 879604 D similar to GP:15155141; identified by sequence similarity; hypothetical protein 879194..879604 Brucella suis 1330 1165342 NP_700066.1 CDS arcB NC_004311.2 879617 880693 R catalyzes the formation of L-proline from L-ornithine; ornithine cyclodeaminase complement(879617..880693) Brucella suis 1330 1165343 NP_700067.1 CDS rocF NC_004311.2 880732 881652 R similar to SP:P10366, GB:U02070, GB:X63697, PID:41022, PID:41708, PID:509817, GB:U00096, PID:1736697, and PID:1788330; identified by sequence similarity; arginase complement(880732..881652) Brucella suis 1330 1165344 NP_700068.1 CDS BRA0901 NC_004311.2 881783 882220 D identified by match to PFAM protein family HMM PF02954; AsnC family transcriptional regulator 881783..882220 Brucella suis 1330 1165345 NP_700069.1 CDS BRA0902 NC_004311.2 882258 883373 R similar to GP:15074497; identified by sequence similarity; FMN-binding oxidoreductase complement(882258..883373) Brucella suis 1330 1165346 NP_700070.1 CDS BRA0903 NC_004311.2 883417 883725 R similar to GP:15074498; identified by sequence similarity; ArsR family transcriptional regulator complement(883417..883725) Brucella suis 1330 1165347 NP_700071.1 CDS BRA0904 NC_004311.2 883943 886246 D similar to SP:P26606, GB:D11109, PID:216433, PID:466645, GB:U00096, and PID:1789924; identified by sequence similarity; tex protein 883943..886246 Brucella suis 1330 1165348 NP_700072.1 CDS BRA0905 NC_004311.2 886341 887624 R similar to GP:15157750; identified by sequence similarity; oxidoreductase complement(886341..887624) Brucella suis 1330 1165349 NP_700073.1 CDS BRA0906 NC_004311.2 887724 888656 R similar to GP:15076313; identified by sequence similarity; LysR family transcriptional regulator complement(887724..888656) Brucella suis 1330 1165350 NP_700074.1 CDS BRA0907 NC_004311.2 888804 890204 D similar to GP:15076314, and GP:15076314; identified by sequence similarity; hypothetical protein 888804..890204 Brucella suis 1330 1165351 NP_700075.1 CDS BRA0908 NC_004311.2 890278 891810 D similar to GP:15076316; identified by sequence similarity; aldehyde dehydrogenase 890278..891810 Brucella suis 1330 1165352 NP_700076.1 CDS purU NC_004311.2 892034 892918 R produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase complement(892034..892918) Brucella suis 1330 1165353 NP_700077.1 CDS BRA0910 NC_004311.2 893062 893790 R identified by match to PFAM protein family HMM PF01380; hypothetical protein complement(893062..893790) Brucella suis 1330 1165354 NP_700078.1 CDS nagA NC_004311.2 893798 894964 R similar to GB:X56652, GB:L05921, GB:M10906, GB:M23698, GB:X51443, SP:P02735, PID:36308, PID:36317, PID:758679, PID:758681, PID:758683, PID:825714, PID:825715, PID:825716, PID:825717, and PID:939926; identified by sequence similarity; N-acetylglucosamine-6-phosphate deacetylase complement(893798..894964) Brucella suis 1330 1165355 NP_700079.1 CDS nagB NC_004311.2 894961 895992 R similar to SP:Q9V249; identified by sequence similarity; glucosamine-fructose-6-phosphate aminotransferase complement(894961..895992) Brucella suis 1330 1165356 NP_700080.1 CDS BRA0913 NC_004311.2 895995 896720 R similar to GP:15073129; identified by sequence similarity; GntR family transcriptional regulator complement(895995..896720) Brucella suis 1330 1165357 NP_700081.1 CDS BRA0914 NC_004311.2 896865 899939 R similar to GP:17984539; identified by sequence similarity; AcrB/AcrD/AcrF multidrug efflux protein complement(896865..899939) Brucella suis 1330 1165358 NP_700082.1 CDS BRA0915 NC_004311.2 899936 901042 R identified by match to TIGR protein family HMM TIGR00998; secretion protein complement(899936..901042) Brucella suis 1330 1165359 NP_700083.1 CDS BRA0916 NC_004311.2 901039 902157 R identified by match to TIGR protein family HMM TIGR00998; HlyD family secretion protein complement(901039..902157) Brucella suis 1330 1165360 NP_700084.1 CDS BRA0917 NC_004311.2 902212 902427 R hypothetical protein complement(902212..902427) Brucella suis 1330 1165361 NP_700085.1 CDS BRA0918 NC_004311.2 902443 902742 R similar to GP:15156636, and GP:15156636; identified by sequence similarity; hypothetical protein complement(902443..902742) Brucella suis 1330 1165362 NP_700086.1 CDS BRA0919 NC_004311.2 902739 905051 R similar to GP:15156635; identified by sequence similarity; molybdopterin-binding oxidoreductase complement(902739..905051) Brucella suis 1330 1165363 NP_700087.1 CDS lldD NC_004311.2 905256 906401 D similar to GP:15141030; identified by sequence similarity; L-lactate dehydrogenase 905256..906401 Brucella suis 1330 1165364 NP_700088.1 CDS BRA0921 NC_004311.2 906680 907534 D similar to GP:15075757, and GP:17742129; identified by sequence similarity; outer surface protein 906680..907534 Brucella suis 1330 1165365 NP_700089.1 CDS BRA0922 NC_004311.2 907682 908149 R similar to GP:5805087, and GP:5805087; identified by sequence similarity; alanine catabolic operon transcriptional regulator complement(907682..908149) Brucella suis 1330 1165366 NP_700090.1 CDS alr NC_004311.2 908399 909589 D identified by match to PFAM protein family HMM PF00842; alanine racemase 908399..909589 Brucella suis 1330 1165367 NP_700091.1 CDS dadA NC_004311.2 909605 910855 D catalyzes the oxidative deamination of D-amino acids; D-amino acid dehydrogenase small subunit 909605..910855 Brucella suis 1330 1165368 NP_700092.1 CDS BRA0925 NC_004311.2 910898 911446 R similar to GP:15076318; identified by sequence similarity; transcriptional regulator complement(910898..911446) Brucella suis 1330 1165369 NP_700093.1 CDS BRA0926 NC_004311.2 911592 912920 D catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate; beta alanine--pyruvate transaminase 911592..912920 Brucella suis 1330 1165370 NP_700094.1 CDS hutC NC_004311.2 912991 913734 R similar to SP:P22773; identified by sequence similarity; histidine utilization repressor complement(912991..913734) Brucella suis 1330 1165371 NP_700095.1 CDS BRA0928 NC_004311.2 913746 915110 R catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate; N-formimino-L-glutamate deiminase complement(913746..915110) Brucella suis 1330 1165372 NP_700096.1 CDS hutI NC_004311.2 915241 916458 D catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 915241..916458 Brucella suis 1330 1165373 NP_700097.1 CDS hutH NC_004311.2 916483 918018 D catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 916483..918018 Brucella suis 1330 1165374 NP_700098.1 CDS hutG NC_004311.2 918020 918820 D similar to GP:15159359; identified by sequence similarity; formiminoglutamase 918020..918820 Brucella suis 1330 1165375 NP_700099.1 CDS hutU NC_004311.2 918831 920504 D catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 918831..920504 Brucella suis 1330 1165376 NP_700100.1 CDS BRA0933 NC_004311.2 920511 921134 D similar to GP:15075729, and GP:15075729; identified by sequence similarity; hypothetical protein 920511..921134 Brucella suis 1330 1165377 NP_700101.1 CDS BRA0934 NC_004311.2 921222 922103 D catalyzes the transamination of D-amino acids and their alpha-keto acids; D-amino acid aminotransferase 921222..922103 Brucella suis 1330 1165378 NP_700102.1 CDS BRA0935 NC_004311.2 922254 923444 R similar to GB:M33819; identified by sequence similarity; sugar ABC transporter permease complement(922254..923444) Brucella suis 1330 1165379 NP_700103.1 CDS BRA0936 NC_004311.2 923444 925033 R similar to GP:15485215; identified by sequence similarity; sugar ABC transporter ATP-binding protein complement(923444..925033) Brucella suis 1330 1165380 NP_700104.1 CDS BRA0937 NC_004311.2 925179 926240 R similar to GB:D14697, GB:J05262, GB:M29863, SP:P14324, PID:182399, PID:182405, PID:285965, and PID:285965; identified by sequence similarity; sugar ABC transporter periplasmic sugar-binding protein complement(925179..926240) Brucella suis 1330 1165381 NP_700105.1 CDS BRA0938 NC_004311.2 926389 927021 R catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism; 2-dehydro-3-deoxy-6-phosphogalactonate aldolase complement(926389..927021) Brucella suis 1330 1165382 NP_700106.1 CDS dgoK NC_004311.2 927018 927947 R similar to GP:15155670, GB:M38180, GB:X55997, GB:M27137, SP:P14060, SP:P26439, PID:177191, PID:177196, PID:179468, PID:23862, PID:287844, and PID:306889; identified by sequence similarity; 2-dehydro-3-deoxygalactonokinase complement(927018..927947) Brucella suis 1330 1165383 NP_700107.1 CDS BRA0940 NC_004311.2 927962 929767 R catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate; dihydroxy-acid dehydratase complement(927962..929767) Brucella suis 1330 1165384 NP_700108.1 CDS BRA0941 NC_004311.2 929864 930799 R similar to GP:15156146, GB:L09118, GB:L23205, SP:Q05940, PID:1220370, PID:1770738, PID:292335, PID:296189, and PID:349712; identified by sequence similarity; D-galactose 1-dehydrogenase complement(929864..930799) Brucella suis 1330 1165385 NP_700109.1 CDS BRA0942 NC_004311.2 930808 931800 R hypothetical protein complement(930808..931800) Brucella suis 1330 1165386 NP_700110.1 CDS BRA0943 NC_004311.2 932070 932363 D hypothetical protein 932070..932363 Brucella suis 1330 1165387 NP_700111.1 CDS BRA0945 NC_004311.2 933065 934750 R catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive; also known as acetolactate synthase large subunit; thiamine pyrophosphate protein complement(933065..934750) Brucella suis 1330 1165389 NP_700112.1 CDS BRA0946 NC_004311.2 934974 935141 D hypothetical protein 934974..935141 Brucella suis 1330 1165390 NP_700113.1 CDS BRA0947 NC_004311.2 935166 936722 D intracellular enzymes acting on low molecular weight D-amino acid amides, esters and oligopeptides containing D-amino acids; these proteases release the N-terminal D-amino acid from a peptide, and show higher affinity for D-Ala, D-Ser or D-Thr; no preference for the stereochemistry of the second amino acid; D-aminopeptidase 935166..936722 Brucella suis 1330 1165391 NP_700114.1 CDS BRA0948 NC_004311.2 936753 937772 R similar to GP:15075720, and SP:P45766; identified by sequence similarity; amino acid ABC transporter substrate-binding protein complement(936753..937772) Brucella suis 1330 1165392 NP_700115.1 CDS BRA0949 NC_004311.2 937876 940947 R similar to GP:15075719; identified by sequence similarity; hypothetical protein complement(937876..940947) Brucella suis 1330 1165393 NP_700116.1 CDS BRA0950 NC_004311.2 941041 941184 R hypothetical protein complement(941041..941184) Brucella suis 1330 1165394 NP_700117.1 CDS BRA0951 NC_004311.2 941198 941638 D similar to GP:15075718; identified by sequence similarity; AsnC family transcriptional regulator 941198..941638 Brucella suis 1330 1165395 NP_700118.1 CDS BRA0952 NC_004311.2 941854 942768 R similar to GP:15075996; identified by sequence similarity; LysR family transcriptional regulator complement(941854..942768) Brucella suis 1330 1165396 NP_700119.1 CDS BRA0953 NC_004311.2 943033 944238 D similar to GP:15159145, and GP:15075607; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 943033..944238 Brucella suis 1330 1165397 NP_700120.1 CDS BRA0954 NC_004311.2 944251 945066 D similar to GP:15159144; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 944251..945066 Brucella suis 1330 1165398 NP_700121.1 CDS BRA0955 NC_004311.2 945059 945784 D similar to GP:15075999, and SP:P22731; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein LivF 945059..945784 Brucella suis 1330 1165399 NP_700122.1 CDS BRA0956 NC_004311.2 945789 946676 D similar to GP:15076000; identified by sequence similarity; branched-chain amino acid ABC transporter permease 945789..946676 Brucella suis 1330 1165400 NP_700123.1 CDS BRA0957 NC_004311.2 946678 947673 D similar to GP:15159141; identified by sequence similarity; branched-chain amino acid ABC transporter permease 946678..947673 Brucella suis 1330 1165401 NP_700124.1 CDS BRA0958 NC_004311.2 947737 949335 D similar to GP:15076002; identified by sequence similarity; GMC family oxidoreductase 947737..949335 Brucella suis 1330 1165402 NP_700125.1 CDS BRA0959 NC_004311.2 949332 949475 D hypothetical protein 949332..949475 Brucella suis 1330 1165403 NP_700126.1 CDS BRA0960 NC_004311.2 949569 950405 D identified by match to PFAM protein family HMM PF03734; YaeC family lipoprotein 949569..950405 Brucella suis 1330 1165404 NP_700127.1 CDS BRA0961 NC_004311.2 950870 951928 D identified by match to TIGR protein family HMM TIGR00972; ABC transporter ATP-binding protein 950870..951928 Brucella suis 1330 1165405 NP_700128.1 CDS BRA0962 NC_004311.2 951909 952574 D identified by match to TIGR protein family HMM TIGR01594; ABC transporter permease 951909..952574 Brucella suis 1330 1165406 NP_700129.1 CDS BRA0963 NC_004311.2 952587 952994 R identified by match to PFAM protein family HMM PF00903; glyoxalase complement(952587..952994) Brucella suis 1330 1165407 NP_700130.1 CDS BRA0964 NC_004311.2 953086 953973 R similar to GP:15075882; identified by sequence similarity; TPR domain-containing protein complement(953086..953973) Brucella suis 1330 1165408 NP_700131.1 CDS BRA0965 NC_004311.2 954067 954228 D hypothetical protein 954067..954228 Brucella suis 1330 1165409 NP_700132.1 CDS rpsU NC_004311.2 954512 954739 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(954512..954739) Brucella suis 1330 1165410 NP_700133.1 CDS BRA0967 NC_004311.2 955092 956288 D similar to GP:15156967, and GP:15156967; identified by sequence similarity; hypothetical protein 955092..956288 Brucella suis 1330 1165411 NP_700134.1 CDS BRA0968 NC_004311.2 956363 956839 R similar to GB:X60708, GB:U13710, GB:U13711, GB:U13712, GB:U13713, GB:U13714, GB:U13715, GB:U13716, GB:U13717, GB:U13718, GB:U13719, GB:U13720, GB:U13721, GB:U13722, GB:U13723, GB:U13724, GB:U13725, GB:U13726, GB:U13727, GB:U13728, GB:U13729, GB:U13730, GB:U13731, GB:U13732, GB:U13733, GB:U13734, GB:U13735, GB:S79876, SP:P27487, PID:180083, PID:181570, PID:35336, and PID:535388; identified by sequence similarity; nodulation protein N complement(956363..956839) Brucella suis 1330 1165412 NP_700135.1 CDS BRA0969 NC_004311.2 956914 957585 R identified by match to TIGR protein family HMM TIGR01662; HAD superfamily hydrolase complement(956914..957585) Brucella suis 1330 1165413 NP_700136.1 CDS BRA0970 NC_004311.2 957781 959097 D identified by match to PFAM protein family HMM PF03447; oxidoreductase 957781..959097 Brucella suis 1330 1165414 NP_700137.1 CDS pntB NC_004311.2 959183 960583 R similar to GP:15075885, GB:M64979, GB:L14754, GB:L24544, SP:P38935, PID:401776, and PID:908917; identified by sequence similarity; NAD(P) transhydrogenase subunit beta complement(959183..960583) Brucella suis 1330 1165415 NP_700138.1 CDS pntAB NC_004311.2 960596 961015 R similar to GP:15075886, GB:V00497, GB:M25113, GB:U01317, GB:M36640, GB:M25660, GB:A01592, GB:A18171, GB:M11428, GB:M25079, GB:V00500, GB:L48213, GB:U20223, GB:V00499, GB:V00498, SP:P02023, SP:P02042, PID:1066755, PID:1066758, PID:1066761, PID:1066764, PID:1066767, PID:1066770, PID:1066773, PID:1066776, PID:1066779, and PID:455998; identified by sequence similarity; NAD(P) transhydrogenase subunit alpha complement(960596..961015) Brucella suis 1330 1165416 NP_700139.1 CDS pntA NC_004311.2 961015 962304 R similar to GB:X70218, SP:P33172, and PID:312814; identified by sequence similarity; NAD(P) transhydrogenase subunit alpha complement(961015..962304) Brucella suis 1330 1165417 NP_700140.1 CDS BRA0974 NC_004311.2 962530 962754 R similar to GP:15075888, and GP:15075888; identified by sequence similarity; hypothetical protein complement(962530..962754) Brucella suis 1330 1165418 NP_700141.1 CDS BRA0975 NC_004311.2 962784 962918 D hypothetical protein 962784..962918 Brucella suis 1330 1165419 NP_700142.1 CDS BRA0976 NC_004311.2 962958 963704 R hypothetical protein complement(962958..963704) Brucella suis 1330 1165420 NP_700143.1 CDS BRA0977 NC_004311.2 963812 963922 R hypothetical protein complement(963812..963922) Brucella suis 1330 1165421 NP_700144.1 CDS BRA0979 NC_004311.2 965445 967742 R identified by match to TIGR protein family HMM TIGR00254; GGDEF domain-containing protein complement(965445..967742) Brucella suis 1330 1165423 NP_700145.1 CDS BRA0980 NC_004311.2 967987 968127 R hypothetical protein complement(967987..968127) Brucella suis 1330 1165424 NP_700146.1 CDS BRA0981 NC_004311.2 968108 968857 R similar to GP:12698385, GB:M62800, GB:U01882, SP:P19474, PID:337485, PID:338490, PID:665918, and PID:747927; identified by sequence similarity; 2-deoxy-D-gluconate 3-dehydrogenase complement(968108..968857) Brucella suis 1330 1165425 NP_700147.1 CDS BRA0982 NC_004311.2 969092 969928 D identified by match to PFAM protein family HMM PF00117; glutamine amidotransferase, class I 969092..969928 Brucella suis 1330 1165426 NP_700148.1 CDS BRA0983 NC_004311.2 969954 970928 R Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; glycerate dehydrogenase complement(969954..970928) Brucella suis 1330 1165427 NP_700149.1 CDS BRA0984 NC_004311.2 971014 972033 R identified by match to TIGR protein family HMM TIGR01481; transcriptional regulator complement(971014..972033) Brucella suis 1330 1165428 NP_700150.1 CDS BRA0986 NC_004311.2 972850 973620 D similar to GP:15075894, GB:X74863, SP:P52954, PID:1617116, and PID:510998; identified by sequence similarity; creatinine amidohydrolase 972850..973620 Brucella suis 1330 1165430 NP_700151.1 CDS BRA0987 NC_004311.2 973856 974980 D similar to GP:15075895; identified by sequence similarity; cobalamin synthesis protein/P47K family protein 973856..974980 Brucella suis 1330 1165431 NP_700152.1 CDS BRA0988 NC_004311.2 975099 976073 D identified by match to PFAM protein family HMM PF00400; hypothetical protein 975099..976073 Brucella suis 1330 1165432 NP_700153.1 CDS BRA0989 NC_004311.2 976190 977056 R similar to GP:15075513, and GP:15075513; identified by sequence similarity; hypothetical protein complement(976190..977056) Brucella suis 1330 1165433 NP_700154.1 CDS BRA0990 NC_004311.2 977479 978438 D in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ; sulfite oxidase subunit YedY 977479..978438 Brucella suis 1330 1165434 NP_700155.1 CDS BRA0991 NC_004311.2 978440 979102 D in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme; sulfite oxidase subunit YedZ 978440..979102 Brucella suis 1330 1165435 NP_700156.1 CDS BRA0992 NC_004311.2 979310 979654 R identified by match to TIGR protein family HMM TIGR00004; hypothetical protein complement(979310..979654) Brucella suis 1330 1165436 NP_700157.1 CDS rbsC-4 NC_004311.2 979729 980682 R similar to GP:15139890; identified by sequence similarity; ribose ABC transporter permease complement(979729..980682) Brucella suis 1330 1165437 NP_700158.1 CDS rbsC-5 NC_004311.2 980679 981638 R similar to SP:P04984; identified by sequence similarity; ribose ABC transporter permease complement(980679..981638) Brucella suis 1330 1165438 NP_700159.1 CDS rbsA-4 NC_004311.2 981638 983146 R identified by match to TIGR protein family HMM TIGR00955; ribose ABC transporter ATP-binding protein complement(981638..983146) Brucella suis 1330 1165439 NP_700160.1 CDS rbsB-3 NC_004311.2 983179 984246 R similar to GP:15139893; identified by sequence similarity; ribose ABC transporter periplasmic D-ribose-binding protein complement(983179..984246) Brucella suis 1330 1165440 NP_700161.1 CDS BRA0997 NC_004311.2 984548 985342 D similar to GP:11275975; identified by sequence similarity; IclR family transcriptional regulator 984548..985342 Brucella suis 1330 1165441 NP_700162.1 CDS BRA0998 NC_004311.2 985436 986617 R similar to GP:5420003, and GP:5420003; identified by sequence similarity; hypothetical protein complement(985436..986617) Brucella suis 1330 1165442 NP_700163.1 CDS BRA0999 NC_004311.2 986785 988815 R similar to GB:M90413, PID:153311, GB:Z22551, GB:D13629, GB:L25616, PID:285985, and PID:409466; identified by sequence similarity; nosA protein complement(986785..988815) Brucella suis 1330 1165443 NP_700164.1 CDS BRA1000 NC_004311.2 988912 989319 R similar to GP:15156545, and GP:15156545; identified by sequence similarity; hypothetical protein complement(988912..989319) Brucella suis 1330 1165444 NP_700165.1 CDS BRA1001 NC_004311.2 989472 989858 R similar to SP:P47233; identified by sequence similarity; extradiol ring-cleaving dioxygenase complement(989472..989858) Brucella suis 1330 1165445 NP_700166.1 CDS BRA1002 NC_004311.2 990041 990646 R similar to SP:P81065, GB:J00117, GB:K03180, GB:K03187, GB:K03188, GB:K03189, GB:X00265, GB:X00266, GB:K03183, GB:K00092, GB:K03182, SP:P01229, SP:P01233, PID:1335012, PID:1335075, PID:180437, PID:180444, and PID:180453; identified by sequence similarity; glutathione S-transferase complement(990041..990646) Brucella suis 1330 1165446 NP_700167.1 CDS BRA1003 NC_004311.2 990750 992051 R hypothetical protein complement(990750..992051) Brucella suis 1330 1165447 NP_700168.1 CDS BRA1004 NC_004311.2 992222 993331 R identified by match to PFAM protein family HMM PF03772; GGDEF domain-containing protein complement(992222..993331) Brucella suis 1330 1165448 NP_700169.1 CDS BRA1005 NC_004311.2 993566 994798 R catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; hydroxyglutarate oxidase complement(993566..994798) Brucella suis 1330 1165449 NP_700170.1 CDS BRA1006 NC_004311.2 994954 995952 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 994954..995952 Brucella suis 1330 1165450 NP_700171.1 CDS BRA1008 NC_004311.2 997431 998279 R similar to GP:15160122; identified by sequence similarity; peptide ABC transporter ATP-binding protein complement(997431..998279) Brucella suis 1330 1165452 NP_700172.1 CDS BRA1009 NC_004311.2 998276 999301 R identified by match to TIGR protein family HMM TIGR01188; peptide ABC transporter ATP-binding protein complement(998276..999301) Brucella suis 1330 1165453 NP_700173.1 CDS BRA1010 NC_004311.2 999298 1000158 R identified by match to PFAM protein family HMM PF03772; peptide ABC transporter permease complement(999298..1000158) Brucella suis 1330 1165454 NP_700174.1 CDS BRA1011 NC_004311.2 1000155 1001108 R identified by match to PFAM protein family HMM PF00528; peptide ABC transporter permease complement(1000155..1001108) Brucella suis 1330 1165455 NP_700175.1 CDS BRA1012 NC_004311.2 1001206 1002684 R identified by match to TIGR protein family HMM TIGR01698; ABC transporter periplasmic substrate-binding protein complement(1001206..1002684) Brucella suis 1330 1165456 NP_700176.1 CDS fabG NC_004311.2 1002707 1003465 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase complement(1002707..1003465) Brucella suis 1330 1165457 NP_700177.1 CDS BRA1014 NC_004311.2 1003500 1004993 R identified by match to TIGR protein family HMM TIGR01682; aldehyde dehydrogenase complement(1003500..1004993) Brucella suis 1330 1165458 NP_700178.1 CDS BRA1015 NC_004311.2 1004977 1005663 R identified by match to PFAM protein family HMM PF01325; GntR family transcriptional regulator complement(1004977..1005663) Brucella suis 1330 1165459 NP_700179.1 CDS BRA1016 NC_004311.2 1005763 1005909 R hypothetical protein complement(1005763..1005909) Brucella suis 1330 1165460 NP_700180.1 CDS BRA1017 NC_004311.2 1006033 1007412 D similar to SP:P76269; identified by sequence similarity; transporter 1006033..1007412 Brucella suis 1330 1165461 NP_700181.1 CDS BRA1018 NC_004311.2 1007806 1008873 D hypothetical protein 1007806..1008873 Brucella suis 1330 1165463 NP_700182.1 CDS BRA1019 NC_004311.2 1008927 1009271 R identified by match to TIGR protein family HMM TIGR00004; hypothetical protein complement(1008927..1009271) Brucella suis 1330 1165464 NP_700183.1 CDS BRA1020 NC_004311.2 1009354 1009578 D hypothetical protein 1009354..1009578 Brucella suis 1330 1165465 NP_700184.1 CDS rpmH NC_004311.2 1009579 1009713 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 1009579..1009713 Brucella suis 1330 1165466 NP_700185.1 CDS rnpA NC_004311.2 1009751 1010188 D protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 1009751..1010188 Brucella suis 1330 1165467 NP_700186.1 CDS BRA1023 NC_004311.2 1010178 1012010 D functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 1010178..1012010 Brucella suis 1330 1165468 NP_700187.1 CDS engB NC_004311.2 1012052 1012855 D binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 1012052..1012855 Brucella suis 1330 1165469 NP_700188.1 CDS argB NC_004311.2 1013026 1013916 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1013026..1013916 Brucella suis 1330 1165470 NP_700189.1 CDS BRA1026 NC_004311.2 1013990 1014694 D identified by match to TIGR protein family HMM TIGR01668; HAD superfamily hydrolase 1013990..1014694 Brucella suis 1330 1165471 NP_700190.1 CDS BRA1027 NC_004311.2 1014756 1015586 R similar to GP:15073363, and GP:15073363; identified by sequence similarity; hypothetical protein complement(1014756..1015586) Brucella suis 1330 1165472 NP_700191.1 CDS dapD NC_004311.2 1015805 1016659 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1015805..1016659 Brucella suis 1330 1165473 NP_700192.1 CDS BRA1029 NC_004311.2 1016803 1017357 R hypothetical protein complement(1016803..1017357) Brucella suis 1330 1165474 NP_700193.1 CDS BRA1030 NC_004311.2 1017510 1017602 D hypothetical protein 1017510..1017602 Brucella suis 1330 1165475 NP_700194.1 CDS dapE NC_004311.2 1017642 1018829 D dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1017642..1018829 Brucella suis 1330 1165476 NP_700195.1 CDS BRA1032 NC_004311.2 1018892 1019497 D similar to GP:15073353; identified by sequence similarity; hypothetical protein 1018892..1019497 Brucella suis 1330 1165477 YP_002519393.1 CDS truA NC_004311.2 1019672 1020427 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1019672..1020427) Brucella suis 1330 1165478 NP_700196.1 CDS fmt NC_004311.2 1020431 1021351 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1020431..1021351) Brucella suis 1330 1165479 NP_700197.1 CDS def NC_004311.2 1021351 1021914 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1021351..1021914) Brucella suis 1330 1165480 NP_700198.1 CDS BRA1036 NC_004311.2 1021981 1023204 D similar to GP:14024818; identified by sequence similarity; hypothetical protein 1021981..1023204 Brucella suis 1330 1165481 NP_700199.1 CDS BRA1037 NC_004311.2 1023433 1023738 R similar to GP:15073194, and GP:15073194; identified by sequence similarity; hypothetical protein complement(1023433..1023738) Brucella suis 1330 1165482 NP_700200.1 CDS BRA1038 NC_004311.2 1023847 1024128 D hypothetical protein 1023847..1024128 Brucella suis 1330 1165483 NP_700201.1 CDS lepA NC_004311.2 1024377 1026185 R binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA complement(1024377..1026185) Brucella suis 1330 1165484 NP_700202.1 CDS BRA1040 NC_004311.2 1026182 1026313 R hypothetical protein complement(1026182..1026313) Brucella suis 1330 1165485 NP_700203.1 CDS BRA1041 NC_004311.2 1026349 1027335 D identified by match to TIGR protein family HMM TIGR01181; NADH-ubiquinone oxidoreductase 1026349..1027335 Brucella suis 1330 1165486 NP_700204.1 CDS uppP NC_004311.2 1027436 1028242 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase complement(1027436..1028242) Brucella suis 1330 1165487 NP_700205.1 CDS BRA1043 NC_004311.2 1028247 1028450 R hypothetical protein complement(1028247..1028450) Brucella suis 1330 1165488 NP_700206.1 CDS BRA1044 NC_004311.2 1028498 1029190 D identified by match to PFAM protein family HMM PF03578; glutathione S-transferase 1028498..1029190 Brucella suis 1330 1165489 NP_700207.1 CDS BRA1045 NC_004311.2 1029171 1030367 D identified by match to PFAM protein family HMM PF00037; (Fe-S)-binding protein 1029171..1030367 Brucella suis 1330 1165490 NP_700208.1 CDS BRA1046 NC_004311.2 1030369 1031238 D similar to GP:15073254; identified by sequence similarity; hypothetical protein 1030369..1031238 Brucella suis 1330 1165491 NP_700209.1 CDS mepA NC_004311.2 1031239 1032261 D D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; penicillin-insensitive murein endopeptidase 1031239..1032261 Brucella suis 1330 1165492 NP_700210.1 CDS mgsA NC_004311.2 1032414 1032791 D catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 1032414..1032791 Brucella suis 1330 1165493 NP_700211.1 CDS glk NC_004311.2 1032872 1033903 D catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate; glucokinase 1032872..1033903 Brucella suis 1330 1165494 NP_700212.1 CDS BRA1050 NC_004311.2 1034130 1035959 D similar to GB:U09086, GB:U09087, GB:U09088, GB:S76736, SP:P42166, SP:P42167, PID:508725, PID:508727, PID:508729, PID:885683, and PID:885684; identified by sequence similarity; ABC transporter ATP-binding/permease 1034130..1035959 Brucella suis 1330 1165495 NP_700213.1 CDS dapB NC_004311.2 1035989 1036795 D catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 1035989..1036795 Brucella suis 1330 1165496 NP_700214.1 CDS gpm NC_004311.2 1036832 1037452 D catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 1036832..1037452 Brucella suis 1330 1165497 NP_700215.1 CDS BRA1053 NC_004311.2 1037873 1039624 D identified by match to PFAM protein family HMM PF03663; hypothetical protein 1037873..1039624 Brucella suis 1330 1165499 NP_700216.1 CDS BRA1054 NC_004311.2 1040135 1040758 D similar to GP:3128327, GB:U05040, and PID:460152; identified by sequence similarity; nitroreductase 1040135..1040758 Brucella suis 1330 1165500 NP_700217.1 CDS BRA1055 NC_004311.2 1040956 1041402 D similar to GP:15155425; identified by sequence similarity; universal stress protein 1040956..1041402 Brucella suis 1330 1165501 NP_700218.1 CDS BRA1056 NC_004311.2 1041519 1041737 R hypothetical protein complement(1041519..1041737) Brucella suis 1330 1165502 NP_700219.1 CDS BRA1057 NC_004311.2 1041891 1042322 D hypothetical protein 1041891..1042322 Brucella suis 1330 1165503 NP_700220.1 CDS BRA1058 NC_004311.2 1042324 1043724 D similar to GP:3336914; identified by sequence similarity; aldehyde dehydrogenase 1042324..1043724 Brucella suis 1330 1165504 NP_700221.1 CDS BRA1059 NC_004311.2 1043879 1044736 D similar to GP:15074185, and GP:15074185; identified by sequence similarity; hypothetical protein 1043879..1044736 Brucella suis 1330 1165505 NP_700222.1 CDS cls NC_004311.2 1044746 1046206 R similar to GP:15157671, and SP:O66043; identified by sequence similarity; cardiolipin synthase complement(1044746..1046206) Brucella suis 1330 1165506 NP_700223.1 CDS BRA1061 NC_004311.2 1046378 1046941 D hypothetical protein 1046378..1046941 Brucella suis 1330 1165507 NP_700224.1 CDS BRA1062 NC_004311.2 1046953 1047066 R hypothetical protein complement(1046953..1047066) Brucella suis 1330 1165508 NP_700225.1 CDS prfC NC_004311.2 1047102 1048679 D identified by match to TIGR protein family HMM TIGR01393; peptide chain release factor 3 1047102..1048679 Brucella suis 1330 1165509 NP_700226.1 CDS coaBC NC_004311.2 1048676 1049896 R catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine; bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase complement(1048676..1049896) Brucella suis 1330 1165510 NP_700227.1 CDS ubiB NC_004311.2 1049927 1051510 R identified by match to PFAM protein family HMM PF00069; ubiquinone biosynthesis protein UbiB complement(1049927..1051510) Brucella suis 1330 1165511 NP_700228.1 CDS ubiE NC_004311.2 1051559 1052368 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; ubiquinone/menaquinone biosynthesis methyltransferase complement(1051559..1052368) Brucella suis 1330 1165512 NP_700229.2 CDS upp NC_004311.2 1052679 1053305 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 1052679..1053305 Brucella suis 1330 1165513 NP_700230.2 CDS BRA1068 NC_004311.2 1053416 1053622 D identified by match to PFAM protein family HMM PF03670; hypothetical protein 1053416..1053622 Brucella suis 1330 1165514 NP_700231.1 CDS msrA NC_004311.2 1053635 1054291 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; methionine sulfoxide reductase A complement(1053635..1054291) Brucella suis 1330 1165515 NP_700232.1 CDS BRA1070 NC_004311.2 1054314 1054637 R hypothetical protein complement(1054314..1054637) Brucella suis 1330 1165516 NP_700233.1 CDS BRA1071 NC_004311.2 1054615 1054767 R hypothetical protein complement(1054615..1054767) Brucella suis 1330 1165517 NP_700234.1 CDS BRA1072 NC_004311.2 1055309 1056217 R similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; IS3 family transposase orfB complement(1055309..1056217) Brucella suis 1330 1165519 NP_700235.1 CDS BRA1073 NC_004311.2 1056214 1056495 R identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA complement(1056214..1056495) Brucella suis 1330 1165520 NP_700236.1 CDS BRA1074 NC_004311.2 1056737 1057468 D identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator 1056737..1057468 Brucella suis 1330 1165521 NP_700237.1 CDS BRA1075 NC_004311.2 1057465 1057593 D hypothetical protein 1057465..1057593 Brucella suis 1330 1165522 NP_700238.1 CDS BRA1076 NC_004311.2 1057664 1059106 R similar to GP:15159844; identified by sequence similarity; aldehyde dehydrogenase complement(1057664..1059106) Brucella suis 1330 1165523 NP_700239.1 CDS BRA1077 NC_004311.2 1059118 1060380 R similar to GP:14587414; identified by sequence similarity; CAIB/BAIF family protein complement(1059118..1060380) Brucella suis 1330 1165524 NP_700240.1 CDS BRA1078 NC_004311.2 1060436 1061440 R similar to GP:3402247; identified by sequence similarity; peptide ABC transporter ATP-binding protein complement(1060436..1061440) Brucella suis 1330 1165525 NP_700241.1 CDS BRA1079 NC_004311.2 1061433 1062470 R similar to GB:M23592, GB:M23593, GB:M23594, GB:M23595, GB:M20841, GB:M74587, GB:M59316, GB:M31145, GB:X12385, GB:X15002, GB:X13405, GB:Y00856, SP:P08833, PID:183118, PID:184810, PID:184812, PID:184826, PID:32609, PID:33014, PID:35572, and PID:35575; identified by sequence similarity; peptide ABC transporter ATP-binding protein complement(1061433..1062470) Brucella suis 1330 1165526 NP_700242.1 CDS BRA1080 NC_004311.2 1062483 1063328 R similar to SP:P94312; identified by sequence similarity; peptide ABC transporter permease complement(1062483..1063328) Brucella suis 1330 1165527 NP_700243.1 CDS BRA1081 NC_004311.2 1063340 1064353 R similar to SP:P94311; identified by sequence similarity; peptide ABC transporter permease complement(1063340..1064353) Brucella suis 1330 1165528 NP_700244.1 CDS BRA1082 NC_004311.2 1064529 1065335 D identified by match to PFAM protein family HMM PF01614; IclR family transcriptional regulator 1064529..1065335 Brucella suis 1330 1165529 NP_700245.1 CDS BRA1084 NC_004311.2 1066765 1068384 R similar to GB:L17071, SP:Q07608, GB:U23753, PID:310304, and PID:763542; identified by sequence similarity; ABC transporter periplasmic substrate-binding protein complement(1066765..1068384) Brucella suis 1330 1165531 NP_700246.1 CDS BRA1086 NC_004311.2 1070601 1072106 R converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation; 3-hydroxyacyl-CoA dehydrogenase complement(1070601..1072106) Brucella suis 1330 1165533 NP_700247.1 CDS BRA1087 NC_004311.2 1072123 1072905 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(1072123..1072905) Brucella suis 1330 1165534 NP_700248.1 CDS BRA1088 NC_004311.2 1073088 1074230 D similar to SP:P45857; identified by sequence similarity; acyl-CoA dehydrogenase 1073088..1074230 Brucella suis 1330 1165535 NP_700249.1 CDS BRA1089 NC_004311.2 1074556 1076841 D similar to SP:P15558; identified by sequence similarity; penicillin amidase 1074556..1076841 Brucella suis 1330 1165536 NP_700250.1 CDS BRA1090 NC_004311.2 1076864 1078408 D similar to GP:15160115, and SP:P55669; identified by sequence similarity; peptide ABC transporter substrate-binding protein 1076864..1078408 Brucella suis 1330 1165537 NP_700251.1 CDS BRA1091 NC_004311.2 1078458 1078553 R hypothetical protein complement(1078458..1078553) Brucella suis 1330 1165538 NP_700252.1 CDS BRA1092 NC_004311.2 1078565 1079509 D similar to GP:10172641, and GP:18092570; identified by sequence similarity; peptide ABC transporter permease 1078565..1079509 Brucella suis 1330 1165539 NP_700253.1 CDS BRA1093 NC_004311.2 1079502 1080392 D similar to GP:15160117, and SP:P94312; identified by sequence similarity; peptide ABC transporter permease 1079502..1080392 Brucella suis 1330 1165540 NP_700254.1 CDS BRA1094 NC_004311.2 1080395 1081393 D similar to GP:15158781; identified by sequence similarity; peptide ABC transporter ATP-binding protein 1080395..1081393 Brucella suis 1330 1165541 NP_700255.1 CDS BRA1096 NC_004311.2 1082617 1083330 D similar to GP:14523620; identified by sequence similarity; transcriptional regulator 1082617..1083330 Brucella suis 1330 1165543 NP_700256.1 CDS BRA1097 NC_004311.2 1083396 1084952 D similar to GP:18092565; identified by sequence similarity; oligopeptide ABC transporter periplasmic oligopeptide-binding protein 1083396..1084952 Brucella suis 1330 1165544 NP_700257.1 CDS BRA1098 NC_004311.2 1084988 1085998 D similar to SP:P94311; identified by sequence similarity; peptide ABC transporter permease 1084988..1085998 Brucella suis 1330 1165545 NP_700258.1 CDS BRA1099 NC_004311.2 1085995 1086828 D similar to SP:P94312; identified by sequence similarity; peptide ABC transporter permease 1085995..1086828 Brucella suis 1330 1165546 NP_700259.1 CDS BRA1101 NC_004311.2 1087816 1088793 D similar to SP:Q53194, GB:M62834, SP:P24093, GB:X69102, PID:145801, PID:433881, PID:639970, and SP:Q57254; identified by sequence similarity; oligopeptide ABC transporter ATP-binding protein 1087816..1088793 Brucella suis 1330 1165548 NP_700260.1 CDS BRA1102 NC_004311.2 1088793 1089665 D similar to GB:M20867, GB:M18377, GB:J03248, GB:M17697, GB:M37154, GB:X07769, GB:X53146, GB:X66300, SP:P00367, SP:P49448, PID:1335082, PID:183054, PID:183056, PID:183058, PID:183060, PID:183062, PID:31707, PID:31799, PID:478988, and PID:579924; identified by sequence similarity; gluconolactonase 1088793..1089665 Brucella suis 1330 1165549 NP_700261.1 CDS BRA1103 NC_004311.2 1089680 1091098 D catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia; amidase 1089680..1091098 Brucella suis 1330 1165550 NP_700262.1 CDS BRA1105 NC_004311.2 1092218 1093021 R identified by match to TIGR protein family HMM TIGR00969; polyamine ABC transporter permease complement(1092218..1093021) Brucella suis 1330 1165552 NP_700263.1 CDS BRA1106 NC_004311.2 1093018 1093833 R similar to SP:P23860, GB:L26967, SP:P12780, PID:152249, and PID:435107; identified by sequence similarity; polyamine ABC transporter permease complement(1093018..1093833) Brucella suis 1330 1165553 NP_700264.1 CDS BRA1108 NC_004311.2 1095294 1096499 D identified by match to PFAM protein family HMM PF03781; glutamate-1-semialdehyde 2,1-aminomutase 1095294..1096499 Brucella suis 1330 1165555 NP_700265.1 CDS BRA1109 NC_004311.2 1096649 1098328 D hypothetical protein 1096649..1098328 Brucella suis 1330 1165556 NP_700266.1 CDS BRA1110 NC_004311.2 1098524 1099183 D similar to GP:15075256, GB:X12466, GB:M37716, GB:M15919, SP:P08578, PID:338267, PID:338269, and PID:35105; identified by sequence similarity; L-fuculose phosphate aldolase 1098524..1099183 Brucella suis 1330 1165557 NP_700267.1 CDS BRA1111 NC_004311.2 1099278 1100537 D similar to GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, PID:386807, GB:J00222, GB:S55273, SP:P01854, PID:184760, PID:2300106, and PID:386807; identified by sequence similarity; hypothetical protein 1099278..1100537 Brucella suis 1330 1165558 NP_700268.1 CDS BRA1112 NC_004311.2 1100515 1101027 D hypothetical protein 1100515..1101027 Brucella suis 1330 1165559 NP_700269.1 CDS BRA1113 NC_004311.2 1101036 1101320 R identified by match to PFAM protein family HMM PF02452; pemK family protein complement(1101036..1101320) Brucella suis 1330 1165560 NP_700270.1 CDS BRA1115 NC_004311.2 1102687 1102968 D identified by match to TIGR protein family HMM TIGR01199; IS3 family transposase orfA 1102687..1102968 Brucella suis 1330 1165562 NP_700271.1 CDS BRA1116 NC_004311.2 1102965 1103846 D similar to GP:581026, GB:U12707, GB:U19927, GB:U18935, and PID:622987; identified by sequence similarity; IS3 family transposase orfB 1102965..1103846 Brucella suis 1330 1165563 NP_700272.1 CDS BRA1117 NC_004311.2 1109574 1109699 R hypothetical protein complement(1109574..1109699) Brucella suis 1330 1165570 NP_700273.1 CDS BRA1118 NC_004311.2 1110339 1111205 D similar to GP:14024748, and GP:14024748; identified by sequence similarity; hypothetical protein 1110339..1111205 Brucella suis 1330 1165571 NP_700274.1 CDS BRA1119 NC_004311.2 1111521 1111916 D identified by match to PFAM protein family HMM PF02082; RrF2 family protein 1111521..1111916 Brucella suis 1330 1165572 NP_700275.1 CDS BRA1120 NC_004311.2 1111977 1113179 R similar to GP:15160214; identified by sequence similarity; cobalamin synthesis protein/P47K family protein complement(1111977..1113179) Brucella suis 1330 1165573 NP_700276.1 CDS BRA1121 NC_004311.2 1113204 1113344 D hypothetical protein 1113204..1113344 Brucella suis 1330 1165574 NP_700277.1 CDS znuA NC_004311.2 1113346 1114350 R similar to GP:15074849, and SP:P39172; identified by sequence similarity; zinc ABC transporter periplasmic zinc-binding protein complement(1113346..1114350) Brucella suis 1330 1165575 NP_700278.1 CDS znuC NC_004311.2 1114577 1115473 D similar to GP:15156606; identified by sequence similarity; zinc ABC transporter ATP-binding protein 1114577..1115473 Brucella suis 1330 1165576 NP_700279.1 CDS znuB NC_004311.2 1115427 1116287 D similar to GP:15074847, and GP:17739944; identified by sequence similarity; zinc ABC transporter permease 1115427..1116287 Brucella suis 1330 1165577 NP_700280.1 CDS BRA1125 NC_004311.2 1116284 1116721 D similar to GP:15156604; identified by sequence similarity; FUR family transcriptional regulator 1116284..1116721 Brucella suis 1330 1165578 NP_700281.1 CDS BRA1126 NC_004311.2 1116848 1117183 D hypothetical protein 1116848..1117183 Brucella suis 1330 1165579 NP_700282.1 CDS BRA1127 NC_004311.2 1117171 1117698 R hypothetical protein complement(1117171..1117698) Brucella suis 1330 1165580 NP_700283.1 CDS BRA1128 NC_004311.2 1117695 1118171 R similar to GP:15073620; identified by sequence similarity; hypothetical protein complement(1117695..1118171) Brucella suis 1330 1165581 NP_700284.1 CDS BRA1129 NC_004311.2 1118312 1118902 R similar to GP:15073619, and GP:15073619; identified by sequence similarity; hypothetical protein complement(1118312..1118902) Brucella suis 1330 1165582 NP_700285.1 CDS BRA1130 NC_004311.2 1118970 1119377 R similar to GP:3876134; identified by sequence similarity; hypothetical protein complement(1118970..1119377) Brucella suis 1330 1165583 NP_700286.1 CDS fliR NC_004311.2 1119385 1120152 R FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthesis protein FliR complement(1119385..1120152) Brucella suis 1330 1165584 NP_700287.1 CDS flhA NC_004311.2 1120168 1122339 R membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA complement(1120168..1122339) Brucella suis 1330 1165585 NP_700288.1 CDS fliQ NC_004311.2 1122419 1122685 R FliQ, with proteins FliP and FliR, forms the core of the central channel in the flagella export apparatus; Bradyrhizobium have one thick flagellum and several thin flagella; the protein in this cluster is associated with the thick flagellum; flagellar biosynthesis protein FliQ complement(1122419..1122685) Brucella suis 1330 1165586 NP_700289.1 CDS flgD NC_004311.2 1122697 1123110 R acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar basal body rod modification protein complement(1122697..1123110) Brucella suis 1330 1165587 NP_700290.1 CDS flbT NC_004311.2 1123107 1123565 R post-transcriptional repressor of flagellum biosynthesis; promotes degradation of fljK mRNA: Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis repressor FlbT complement(1123107..1123565) Brucella suis 1330 1165588 NP_700291.1 CDS flaF NC_004311.2 1123567 1123911 R acts as an activator or flagellin translation and may be required for filament secretion or assembly; Bradyrhizobium has one thick flagellum and several thin flagella; the protein in this cluster is associated with the thin flagella; flagellar biosynthesis regulatory protein FlaF complement(1123567..1123911) Brucella suis 1330 1165589 NP_700292.1 CDS flgL NC_004311.2 1124043 1125089 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Bradyrhizobium has one thick flagellum and several thin flagella; the Bradyrhizobium protein in this cluster is associated with the thin flagella; flagellar hook-associated protein FlgL complement(1124043..1125089) Brucella suis 1330 1165590 NP_700293.1 CDS flgK NC_004311.2 1125095 1126549 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein FlgK complement(1125095..1126549) Brucella suis 1330 1165591 NP_700294.1 CDS flgE NC_004311.2 1126674 1127864 R the hook connects flagellar basal body to the flagellar filament; flagellar hook protein FlgE complement(1126674..1127864) Brucella suis 1330 1165592 NP_700295.1 CDS BRA1140 NC_004311.2 1128275 1128958 R similar to GP:15073608; identified by sequence similarity; transcriptional regulator complement(1128275..1128958) Brucella suis 1330 1165593 NP_700296.1 CDS BRA1141 NC_004311.2 1129286 1129858 R similar to GP:15073607, and GP:15073607; identified by sequence similarity; hypothetical protein complement(1129286..1129858) Brucella suis 1330 1165594 NP_700297.1 CDS BRA1142 NC_004311.2 1129812 1131074 R similar to GP:15155510, and SP:Q52964; identified by sequence similarity; motD-like protein complement(1129812..1131074) Brucella suis 1330 1165595 NP_700298.1 CDS motB NC_004311.2 1132372 1133472 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; flagellar motor protein MotB complement(1132372..1133472) Brucella suis 1330 1165597 NP_700299.1 CDS BRA1145 NC_004311.2 1133469 1134149 R similar to GP:15155507, and GP:12057223; identified by sequence similarity; hypothetical protein complement(1133469..1134149) Brucella suis 1330 1165598 NP_700300.1 CDS fliF NC_004311.2 1134152 1135894 R the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein complement(1134152..1135894) Brucella suis 1330 1165599 NP_700301.1 CDS BRA1147 NC_004311.2 1136107 1136955 R similar to GP:2832232; identified by sequence similarity; flagellin family protein complement(1136107..1136955) Brucella suis 1330 1165600 NP_700302.1 CDS BRA1148 NC_004311.2 1137593 1147855 D similar to GP:15162141, and GP:15162141; identified by sequence similarity; outer membrane autotransporter 1137593..1147855 Brucella suis 1330 1165601 NP_700303.1 CDS BRA1149 NC_004311.2 1147972 1149027 R hypothetical protein complement(1147972..1149027) Brucella suis 1330 1165602 NP_700304.1 CDS xylF NC_004311.2 1149601 1150620 D similar to GB:X03656, GB:X03438, GB:M17706, SP:P09919, PID:1330309, PID:1330310, PID:183041, PID:183045, PID:296647, PID:31690, and PID:732764; identified by sequence similarity; D-xylose ABC transporter periplasmic D-xylose-binding protein 1149601..1150620 Brucella suis 1330 1165603 NP_700305.1 CDS xylG NC_004311.2 1150782 1152317 D with XylFH is part of the high affinity xylose ABC transporter; xylose transporter ATP-binding subunit 1150782..1152317 Brucella suis 1330 1165604 NP_700306.1 CDS xylH NC_004311.2 1152460 1153629 D similar to GB:L17326, and PID:306325; identified by sequence similarity; D-xylose ABC transporter permease 1152460..1153629 Brucella suis 1330 1165605 NP_700307.1 CDS BRA1153 NC_004311.2 1153673 1153876 D hypothetical protein 1153673..1153876 Brucella suis 1330 1165606 NP_700308.1 CDS BRA1154 NC_004311.2 1154187 1155155 D similar to SP:P36673, GB:U07790, PID:465107, PID:537083, GB:U00096, PID:1790689, and PID:1843456; identified by sequence similarity; AraC family transcriptional regulator 1154187..1155155 Brucella suis 1330 1165607 NP_700309.1 CDS BRA1155 NC_004311.2 1155255 1156661 D similar to GP:4566586; identified by sequence similarity; aldehyde dehydrogenase 1155255..1156661 Brucella suis 1330 1165608 NP_700310.1 CDS BRA1156 NC_004311.2 1156818 1157627 R similar to GB:M79446, SP:P24182, GB:M83198, PID:145175, PID:145893, PID:145896, PID:606196, GB:U00096, PID:1789654, GB:U03272, SP:P35556, and PID:437972; identified by sequence similarity; 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase complement(1156818..1157627) Brucella suis 1330 1165609 NP_700311.1 CDS BRA1157 NC_004311.2 1157694 1157804 R hypothetical protein complement(1157694..1157804) Brucella suis 1330 1165610 NP_700312.1 CDS hpaH NC_004311.2 1157845 1158648 R similar to GB:M98276, SP:Q04626, GB:M64046, PID:151020, PID:45360, SP:P77915, PID:1515308, GB:M13300, GB:M13301, GB:M13302, GB:M13303, GB:M13304, GB:M13305, GB:X54705, GB:X54675, GB:Z68193, SP:P04000, SP:P04001, PID:1122284, and PID:180703; identified by sequence similarity; 2-keto-4-pentenoate hydratase complement(1157845..1158648) Brucella suis 1330 1165611 NP_700313.1 CDS BRA1159 NC_004311.2 1158652 1159518 R similar to GP:14424793; identified by sequence similarity; fumarylacetoacetate hydrolase complement(1158652..1159518) Brucella suis 1330 1165612 NP_700314.1 CDS BRA1161 NC_004311.2 1160622 1162136 R similar to GB:X75771, and PID:455422; identified by sequence similarity; 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase complement(1160622..1162136) Brucella suis 1330 1165614 NP_700315.1 CDS hpcD NC_004311.2 1162206 1162598 R similar to GP:10048282, and SP:Q05354; identified by sequence similarity; 5-carboxymethyl-2-hydroxymuconate delta-isomerase complement(1162206..1162598) Brucella suis 1330 1165615 NP_700316.1 CDS BRA1163 NC_004311.2 1162764 1163255 D identified by match to PFAM protein family HMM PF03551; MarR family transcriptional regulator 1162764..1163255 Brucella suis 1330 1165616 NP_700317.1 CDS BRA1164 NC_004311.2 1163245 1164264 R similar to GP:15162021, and GP:14026357; identified by sequence similarity; hypothetical protein complement(1163245..1164264) Brucella suis 1330 1165617 NP_700318.1 CDS BRA1165 NC_004311.2 1164242 1165525 R similar to GP:14524116; identified by sequence similarity; aminotransferase complement(1164242..1165525) Brucella suis 1330 1165618 NP_700319.1 CDS BRA1166 NC_004311.2 1165527 1166885 R identified by match to TIGR protein family HMM TIGR00699; hypothetical protein complement(1165527..1166885) Brucella suis 1330 1165619 NP_700320.1 CDS BRA1167 NC_004311.2 1166898 1167542 R similar to GB:M60787, and PID:150163; identified by sequence similarity; HAD superfamily hydrolase complement(1166898..1167542) Brucella suis 1330 1165620 NP_700321.1 CDS BRA1168 NC_004311.2 1167539 1168795 R similar to GP:14271863; identified by sequence similarity; hypothetical protein complement(1167539..1168795) Brucella suis 1330 1165621 NP_700322.1 CDS BRA1169 NC_004311.2 1168795 1169577 R similar to GB:D12765, SP:P43268, PID:219611, and PID:602288; identified by sequence similarity; IclR family transcriptional regulator complement(1168795..1169577) Brucella suis 1330 1165622 NP_700323.1 CDS BRA1170 NC_004311.2 1169827 1171320 D similar to GP:5441757; identified by sequence similarity; amino acid permease 1169827..1171320 Brucella suis 1330 1165623 NP_700324.1 CDS BRA1171 NC_004311.2 1171392 1172870 D similar to GB:M11147, GB:M10119, GB:M12938, GB:X03742, GB:X03743, SP:P02792, PID:1340145, PID:1340146, PID:182514, PID:182516, PID:182518, PID:2230869, and PID:28519; identified by sequence similarity; aldehyde dehydrogenase 1171392..1172870 Brucella suis 1330 1165624 NP_700325.1 CDS BRA1172 NC_004311.2 1173029 1174711 D hypothetical protein 1173029..1174711 Brucella suis 1330 1165625 NP_700326.1 CDS BRA1173 NC_004311.2 1174778 1175959 D branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1174778..1175959 Brucella suis 1330 1165626 NP_700327.1 CDS BRA1174 NC_004311.2 1176032 1176901 D similar to GP:9716222; identified by sequence similarity; branched-chain amino acid ABC transporter permease 1176032..1176901 Brucella suis 1330 1165627 NP_700328.1 CDS BRA1175 NC_004311.2 1176888 1178600 D similar to GP:15156481; identified by sequence similarity; branched chain amino acid ABC transporter ATP-binding/permease 1176888..1178600 Brucella suis 1330 1165628 NP_700329.1 CDS BRA1176 NC_004311.2 1178597 1179301 D similar to GB:M16442, and PID:143790; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1178597..1179301 Brucella suis 1330 1165629 NP_700330.1 CDS BRA1177 NC_004311.2 1179396 1179719 R identified by match to PFAM protein family HMM PF03988; hypothetical protein complement(1179396..1179719) Brucella suis 1330 1165630 NP_700331.1 CDS BRA1178 NC_004311.2 1179734 1180603 R identified by match to PFAM protein family HMM PF03741; hypothetical protein complement(1179734..1180603) Brucella suis 1330 1165631 NP_700332.1 CDS BRA1179 NC_004311.2 1180609 1181343 R identified by match to PFAM protein family HMM PF00392; GntR family transcriptional regulator complement(1180609..1181343) Brucella suis 1330 1165632 NP_700333.1 CDS BRA1180 NC_004311.2 1181488 1182753 R sugar ABC transporter periplasmic sugar-binding protein complement(1181488..1182753) Brucella suis 1330 1165633 NP_700334.1 CDS BRA1181 NC_004311.2 1182788 1183609 R identified by match to TIGR protein family HMM TIGR00023; sugar ABC transporter permease complement(1182788..1183609) Brucella suis 1330 1165634 NP_700335.1 CDS BRA1182 NC_004311.2 1183620 1184579 R identified by match to TIGR protein family HMM TIGR00969; sugar ABC transporter permease complement(1183620..1184579) Brucella suis 1330 1165635 NP_700336.1 CDS BRA1183 NC_004311.2 1184545 1185723 R similar to SP:Q01937; identified by sequence similarity; sugar ABC transporter ATP-binding protein complement(1184545..1185723) Brucella suis 1330 1165636 NP_700337.1 CDS BRA1184 NC_004311.2 1185720 1186565 R identified by match to PFAM protein family HMM PF00149; purple acid phosphatase complement(1185720..1186565) Brucella suis 1330 1165637 NP_700338.1 CDS BRA1185 NC_004311.2 1186840 1188327 R identified by match to PFAM protein family HMM PF00884; sulfatase complement(1186840..1188327) Brucella suis 1330 1165638 NP_700339.1 CDS BRA1186 NC_004311.2 1188470 1189429 R similar to GP:7799282, and SP:Q47537; identified by sequence similarity; taurine ABC transporter taurine-binding protein complement(1188470..1189429) Brucella suis 1330 1165639 NP_700340.1 CDS BRA1187 NC_004311.2 1189445 1190227 R similar to GP:7799281; identified by sequence similarity; taurine ABC transporter ATP-binding protein complement(1189445..1190227) Brucella suis 1330 1165640 NP_700341.1 CDS BRA1188 NC_004311.2 1190224 1190976 R similar to GP:7799280, and SP:Q47539; identified by sequence similarity; taurine ABC transporter permease complement(1190224..1190976) Brucella suis 1330 1165641 NP_700342.1 CDS BRA1189 NC_004311.2 1190973 1192097 R similar to GP:2661680; identified by sequence similarity; ROK family protein complement(1190973..1192097) Brucella suis 1330 1165642 NP_700343.1 CDS BRA1190 NC_004311.2 1192353 1194338 R similar to GB:X73376, GB:X73377, GB:X73378, GB:X73379, GB:X73380, GB:X73381, GB:X73382, GB:X73384, GB:X73385, PID:475179, and PID:475185; identified by sequence similarity; TonB dependent receptor domain-containing protein complement(1192353..1194338) Brucella suis 1330 1165643 NP_700344.1 CDS BRA1191 NC_004311.2 1194335 1194457 R hypothetical protein complement(1194335..1194457) Brucella suis 1330 1165644 NP_700345.1 CDS BRA1192 NC_004311.2 1194806 1195585 D identified by match to PFAM protein family HMM PF00191; AraC family transcriptional regulator 1194806..1195585 Brucella suis 1330 1165645 NP_700346.1 CDS BRA1193 NC_004311.2 1195735 1196955 D similar to GP:151110, and SP:P04816; identified by sequence similarity; branched-chain amino acid ABC transporter periplasmic amino acid-binding protein 1195735..1196955 Brucella suis 1330 1165646 NP_700347.1 CDS BRA1194 NC_004311.2 1197157 1198020 D similar to GB:L19201, SP:P32174, PID:304996, GB:U00096, and PID:1790325; identified by sequence similarity; branched-chain amino acid ABC transporter permease 1197157..1198020 Brucella suis 1330 1165647 NP_700348.1 CDS BRA1196 NC_004311.2 1198961 1199695 D similar to GB:M59757, SP:P25993, PID:143389, and GB:AL009126; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1198961..1199695 Brucella suis 1330 1165649 NP_700349.1 CDS BRA1197 NC_004311.2 1199692 1200420 D similar to SP:P22731, GB:M16442, and PID:143790; identified by sequence similarity; branched-chain amino acid ABC transporter ATP-binding protein 1199692..1200420 Brucella suis 1330 1165650 NP_700350.1 CDS cadA-2 NC_004311.2 1200449 1202389 R similar to GP:3128316, and GP:17984226; identified by sequence similarity; cadmium-translocating P-type ATPase complement(1200449..1202389) Brucella suis 1330 1165651 NP_700351.1 CDS hemN-2 NC_004311.2 1202669 1204021 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1202669..1204021) Brucella suis 1330 1165652 NP_700352.1 CDS BRA1200 NC_004311.2 1204114 1204338 R hypothetical protein complement(1204114..1204338) Brucella suis 1330 1165653 NP_700353.1 CDS BRA1201 NC_004311.2 1204305 1204709 R hypothetical protein complement(1204305..1204709) Brucella suis 1330 1165654 NP_700354.1 CDS repA NC_004311.2 1204923 1206116 D identified by match to TIGR protein family HMM TIGR01281; replication protein RepA 1204923..1206116 Brucella suis 1330 1165655 NP_700355.1 CDS BRA1203 NC_004311.2 1206181 1207167 D similar to SP:P55392; identified by sequence similarity; replication protein RepB 1206181..1207167 Brucella suis 1330 1165656 BR_t01 tRNA BR_t01 NC_004310.3 28319 28391 R tRNA-Ala complement(28319..28391) Brucella suis 1330 3365387 BR_t02 tRNA BR_t02 NC_004310.3 207695 207768 D tRNA-Pro 207695..207768 Brucella suis 1330 3365361 BR_t03 tRNA BR_t03 NC_004310.3 258918 258990 R tRNA-Phe complement(258918..258990) Brucella suis 1330 3365406 BR_t04 tRNA BR_t04 NC_004310.3 265276 265347 D tRNA-Thr 265276..265347 Brucella suis 1330 3365362 BR_t05 tRNA BR_t05 NC_004310.3 279424 279497 R tRNA-Arg complement(279424..279497) Brucella suis 1330 3365405 BR_t06 tRNA BR_t06 NC_004310.3 513096 513167 D tRNA-Gln 513096..513167 Brucella suis 1330 3365363 BR_t07 tRNA BR_t07 NC_004310.3 631968 632055 R tRNA-Ser complement(631968..632055) Brucella suis 1330 3365404 BR_t08 tRNA BR_t08 NC_004310.3 705132 705205 D tRNA-Pro 705132..705205 Brucella suis 1330 3365371 BR_t09 tRNA BR_t09 NC_004310.3 705770 705843 D tRNA-Arg 705770..705843 Brucella suis 1330 3365372 BR_t10 tRNA BR_t10 NC_004310.3 764351 764424 R tRNA-Pro complement(764351..764424) Brucella suis 1330 3365403 BR_t11 tRNA BR_t11 NC_004310.3 777998 778070 R tRNA-Val complement(777998..778070) Brucella suis 1330 3365402 BR_t12 tRNA BR_t12 NC_004310.3 778480 778553 D tRNA-Asp 778480..778553 Brucella suis 1330 3365373 BR_t13 tRNA BR_t13 NC_004310.3 871385 871464 D tRNA-Leu 871385..871464 Brucella suis 1330 3365374 BR_t14 tRNA BR_t14 NC_004310.3 910553 910625 R tRNA-Thr complement(910553..910625) Brucella suis 1330 3365401 BR_t15 tRNA BR_t15 NC_004310.3 936382 936453 R tRNA-Val complement(936382..936453) Brucella suis 1330 3365400 BR_t16 tRNA BR_t16 NC_004310.3 936870 936943 D tRNA-Arg 936870..936943 Brucella suis 1330 3365375 BR_t17 tRNA BR_t17 NC_004310.3 937651 937721 R tRNA-Gly complement(937651..937721) Brucella suis 1330 3365399 BR_t18 tRNA BR_t18 NC_004310.3 1019437 1019519 D tRNA-Leu 1019437..1019519 Brucella suis 1330 3365376 BR_t19 tRNA BR_t19 NC_004310.3 1048185 1048266 D tRNA-Leu 1048185..1048266 Brucella suis 1330 3365377 BR_t20 tRNA BR_t20 NC_004310.3 1055930 1056011 D tRNA-Leu 1055930..1056011 Brucella suis 1330 3365378 BR_t21 tRNA BR_t21 NC_004310.3 1218578 1218650 R tRNA-Trp complement(1218578..1218650) Brucella suis 1330 3365398 BR_t22 tRNA BR_t22 NC_004310.3 1220076 1220146 R tRNA-Gly complement(1220076..1220146) Brucella suis 1330 3365397 BR_t23 tRNA BR_t23 NC_004310.3 1220174 1220255 R tRNA-Tyr complement(1220174..1220255) Brucella suis 1330 3365386 BR_t24 tRNA BR_t24 NC_004310.3 1241104 1241175 D tRNA-Glu 1241104..1241175 Brucella suis 1330 3365379 BR_t25 tRNA BR_t25 NC_004310.3 1241326 1241397 D tRNA-Glu 1241326..1241397 Brucella suis 1330 3365366 BR_t26 tRNA BR_t26 NC_004310.3 1297468 1297540 D tRNA-Lys 1297468..1297540 Brucella suis 1330 3365367 BR_t27 tRNA BR_t27 NC_004310.3 1429305 1429378 R tRNA-Met complement(1429305..1429378) Brucella suis 1330 3365385 BR_t28 tRNA BR_t28 NC_004310.3 1547758 1547831 D tRNA-Met 1547758..1547831 Brucella suis 1330 3365368 BR_t29 tRNA BR_t29 NC_004310.3 1549517 1549590 R tRNA-His complement(1549517..1549590) Brucella suis 1330 3365384 BR_t30 tRNA BR_t30 NC_004310.3 1564017 1564087 D tRNA-Gln 1564017..1564087 Brucella suis 1330 3365369 BR_t31 tRNA BR_t31 NC_004310.3 1584416 1584489 R tRNA-Met complement(1584416..1584489) Brucella suis 1330 3365383 BR_t32 tRNA BR_t32 NC_004310.3 1588158 1588230 R tRNA-Ala complement(1588158..1588230) Brucella suis 1330 3365382 BR_t33 tRNA BR_t33 NC_004310.3 1588247 1588320 R tRNA-Ile complement(1588247..1588320) Brucella suis 1330 3365381 BR_t34 tRNA BR_t34 NC_004310.3 1603269 1603340 D tRNA-Glu 1603269..1603340 Brucella suis 1330 3365370 BR_t35 tRNA BR_t35 NC_004310.3 1781424 1781510 D tRNA-Ser 1781424..1781510 Brucella suis 1330 3365407 BR_t36 tRNA BR_t36 NC_004310.3 1789478 1789551 R tRNA-Met complement(1789478..1789551) Brucella suis 1330 3365380 BR_t37 tRNA BR_t37 NC_004310.3 1793220 1793292 R tRNA-Ala complement(1793220..1793292) Brucella suis 1330 3365364 BR_t38 tRNA BR_t38 NC_004310.3 1793309 1793382 R tRNA-Ile complement(1793309..1793382) Brucella suis 1330 3365365 BR_t39 tRNA BR_t39 NC_004310.3 1881678 1881759 D tRNA-Leu 1881678..1881759 Brucella suis 1330 3365394 BR_t40 tRNA BR_t40 NC_004310.3 1919132 1919204 R tRNA-Ala complement(1919132..1919204) Brucella suis 1330 3365396 BR_t41 tRNA BR_t41 NC_004310.3 1963450 1963523 D tRNA-Arg 1963450..1963523 Brucella suis 1330 3365395 BRAt01 tRNA tRNA-Val-3 NC_004311.2 39421 39495 R tRNA-Val complement(39421..39495) Brucella suis 1330 1164479 BRAt02 tRNA tRNA-Asp-2 NC_004311.2 304982 305058 R tRNA-Asp complement(304982..305058) Brucella suis 1330 1164762 BRAt03 tRNA tRNA-Ser-4 NC_004311.2 539952 540041 R tRNA-Ser complement(539952..540041) Brucella suis 1330 1164999 BRAt04 tRNA tRNA-Lys-2 NC_004311.2 572417 572492 R tRNA-Lys complement(572417..572492) Brucella suis 1330 1165026 BRAt05 tRNA tRNA-Cys-1 NC_004311.2 604389 604462 D tRNA-Cys 604389..604462 Brucella suis 1330 1165058 BRAt06 tRNA tRNA-Asn-1 NC_004311.2 608750 608824 R tRNA-Asn complement(608750..608824) Brucella suis 1330 1165068 BRAt07 tRNA tRNA-Thr-3 NC_004311.2 818236 818311 D tRNA-Thr 818236..818311 Brucella suis 1330 1165275 BRAt08 tRNA tRNA-Gly-4 NC_004311.2 878530 878604 D tRNA-Gly 878530..878604 Brucella suis 1330 1165339 BRAt09 tRNA tRNA-Gly-3 NC_004311.2 1007558 1007632 D tRNA-Gly 1007558..1007632 Brucella suis 1330 1165462 BRAt10 tRNA tRNA-Leu-6 NC_004311.2 1037602 1037688 D tRNA-Leu 1037602..1037688 Brucella suis 1330 1165498 BRAt11 tRNA tRNA-Ser-3 NC_004311.2 1055010 1055099 D tRNA-Ser 1055010..1055099 Brucella suis 1330 1165518 BRAt12 tRNA tRNA-Met-5 NC_004311.2 1103952 1104028 R tRNA-Met complement(1103952..1104028) Brucella suis 1330 1165564 BRAt13 tRNA tRNA-Ala-5 NC_004311.2 1107694 1107769 R tRNA-Ala complement(1107694..1107769) Brucella suis 1330 1165567 BRAt14 tRNA tRNA-Ile-3 NC_004311.2 1107783 1107859 R tRNA-Ile complement(1107783..1107859) Brucella suis 1330 1165568 BR_r01 rRNA BR_r01 NC_004310.3 1584588 1584713 R 5S ribosomal RNA complement(1584588..1584713) Brucella suis 1330 3365388 BR_r02 rRNA BR_r02 NC_004310.3 1584926 1587833 R 23S ribosomal RNA complement(1584926..1587833) Brucella suis 1330 3365392 BR_r03 rRNA BR_r03 NC_004310.3 1588596 1590086 R 16S ribosomal RNA complement(1588596..1590086) Brucella suis 1330 3365390 BR_r04 rRNA BR_r04 NC_004310.3 1789650 1789775 R 5S ribosomal RNA complement(1789650..1789775) Brucella suis 1330 3365389 BR_r05 rRNA BR_r05 NC_004310.3 1789988 1792895 R 23S ribosomal RNA complement(1789988..1792895) Brucella suis 1330 3365393 BR_r06 rRNA BR_r06 NC_004310.3 1793658 1795148 R 16S ribosomal RNA complement(1793658..1795148) Brucella suis 1330 3365391 BRAr01 rRNA Bs5SD NC_004311.2 1104133 1104251 R 5S ribosomal RNA complement(1104133..1104251) Brucella suis 1330 1165565 BRAr02 rRNA Bs23SC NC_004311.2 1104564 1107372 R 23S ribosomal RNA complement(1104564..1107372) Brucella suis 1330 1165566 BRAr03 rRNA Bs16SC NC_004311.2 1108162 1109615 R 16S ribosomal RNA complement(1108162..1109615) Brucella suis 1330 1165569