-- dump date 20140619_011725 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_002467775.1 219681390 7262729 197..2083 1 NC_011833.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2083 gidA 7262729 gidA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_002467775.1 197 D 563178 CDS YP_002467776.1 219681391 7262348 2278..3102 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 3102 atpB 7262348 atpB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit A YP_002467776.1 2278 D 563178 CDS YP_002467777.1 219681392 7262349 3139..3378 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 3378 atpE 7262349 atpE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit C YP_002467777.1 3139 D 563178 CDS YP_002467778.1 219681393 7262350 3497..3982 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B 3982 atpF 7262350 atpF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit B YP_002467778.1 3497 D 563178 CDS YP_002467779.1 219681394 7262351 3982..4515 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta 4515 atpH 7262351 atpH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit delta YP_002467779.1 3982 D 563178 CDS YP_002467780.1 219681395 7262352 4530..6068 1 NC_011833.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 6068 atpA 7262352 atpA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit alpha YP_002467780.1 4530 D 563178 CDS YP_002467781.1 219681396 7262353 6101..6973 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma 6973 atpG 7262353 atpG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit gamma YP_002467781.1 6101 D 563178 CDS YP_002467782.1 219681397 7262354 6997..8394 1 NC_011833.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta 8394 atpD 7262354 atpD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit beta YP_002467782.1 6997 D 563178 CDS YP_002467783.1 219681398 7262355 8421..8837 1 NC_011833.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon 8837 atpC 7262355 atpC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) F0F1 ATP synthase subunit epsilon YP_002467783.1 8421 D 563178 CDS YP_002467784.1 219681399 7262356 complement(8911..11322) 1 NC_011833.1 DNA gyrase subunit B 11322 gyrB 7262356 gyrB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA gyrase subunit B YP_002467784.1 8911 R 563178 CDS YP_002467785.1 219681400 7262357 complement(11449..12549) 1 NC_011833.1 DNA polymerase III, beta subunit; DNA polymerase III beta chain 12549 dnaN 7262357 dnaN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III beta chain YP_002467785.1 11449 R 563178 CDS YP_002467786.1 219681401 7262358 complement(12554..13918) 1 NC_011833.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 13918 dnaA 7262358 dnaA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chromosomal replication initiation protein YP_002467786.1 12554 R 563178 CDS YP_002467787.1 219681402 7262359 14369..14512 1 NC_011833.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 14512 rpmH 7262359 rpmH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L34 YP_002467787.1 14369 D 563178 CDS YP_002467788.1 219681403 7262361 15010..16608 1 NC_011833.1 protein translocase subunit yidC; 60 kDa inner-membrane protein 16608 yidC 7262361 yidC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 60 kDa inner-membrane protein YP_002467788.1 15010 D 563178 CDS YP_002467789.1 219681404 7262362 16647..18008 1 NC_011833.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 18008 trmE 7262362 trmE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA modification GTPase TrmE YP_002467789.1 16647 D 563178 CDS YP_002467790.1 219681405 7262364 18375..18665 1 NC_011833.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 18665 groES 7262364 groES Buchnera aphidicola str. 5A (Acyrthosiphon pisum) co-chaperonin GroES YP_002467790.1 18375 D 563178 CDS YP_002467791.1 219681406 7262365 18714..20360 1 NC_011833.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 20360 groEL 7262365 groEL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chaperonin GroEL YP_002467791.1 18714 D 563178 CDS YP_002467792.1 219681407 7262366 20985..21596 1 NC_011833.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 21596 efp 7262366 efp Buchnera aphidicola str. 5A (Acyrthosiphon pisum) elongation factor P YP_002467792.1 20985 D 563178 CDS YP_002467793.1 219681408 7262367 complement(21614..22354) 1 NC_011833.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 22354 dnaC 7262367 dnaC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA replication protein DnaC YP_002467793.1 21614 R 563178 CDS YP_002467794.1 219681409 7262368 complement(22354..22848) 1 NC_011833.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 22848 dnaT 7262368 dnaT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) primosomal protein DnaI YP_002467794.1 22354 R 563178 CDS YP_002467795.1 219681410 7262369 complement(22945..23520) 1 NC_011833.1 16S rRNA m2G966 methyltransferase (YhhF) 23520 rsmD 7262369 rsmD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 16S rRNA m2G966 methyltransferase (YhhF) YP_002467795.1 22945 R 563178 CDS YP_002467796.1 219681411 7262370 23651..24787 1 NC_011833.1 signal recognition particle-docking protein FtsY; cell division protein FtsY 24787 ftsY 7262370 ftsY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsY YP_002467796.1 23651 D 563178 CDS YP_002467797.1 219681412 7262371 24950..25804 1 NC_011833.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 25804 rpoH 7262371 rpoH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) RNA polymerase factor sigma-32 YP_002467797.1 24950 D 563178 CDS YP_002467798.1 219681413 7262372 complement(25945..27774) 1 NC_011833.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 27774 glmS 7262372 glmS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glucosamine--fructose-6-phosphate aminotransferase YP_002467798.1 25945 R 563178 CDS YP_002467799.1 219681414 7262373 complement(27844..29223) 1 NC_011833.1 UDP-N-acetylglucosamine pyrophosphorylase 29223 glmU 7262373 glmU Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylglucosamine pyrophosphorylase YP_002467799.1 27844 R 563178 CDS YP_002467800.1 219681415 7262374 29403..30221 1 NC_011833.1 sugar phosphatase 30221 yigL 7262374 yigL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sugar phosphatase YP_002467800.1 29403 D 563178 CDS YP_002467801.1 219681416 7262375 31192..33468 1 NC_011833.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 33468 metE 7262375 metE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase YP_002467801.1 31192 D 563178 CDS YP_002467802.1 219681417 7262376 complement(33591..35168) 1 NC_011833.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 35168 purH 7262376 purH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase YP_002467802.1 33591 R 563178 CDS YP_002467803.1 219681418 7262377 complement(35309..35587) 1 NC_011833.1 bacterial nucleoid protein Hbs; DNA-binding protein hu-alpha 35587 hupA 7262377 hupA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA-binding protein hu-alpha YP_002467803.1 35309 R 563178 CDS YP_002467804.1 219681419 7262378 complement(36321..40544) 1 NC_011833.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 40544 rpoC 7262378 rpoC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit beta' YP_002467804.1 36321 R 563178 CDS YP_002467805.1 219681420 7262379 complement(40622..44650) 1 NC_011833.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 44650 rpoB 7262379 rpoB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit beta YP_002467805.1 40622 R 563178 CDS YP_002467806.1 219681421 7262380 complement(44870..45238) 1 NC_011833.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 45238 rplL 7262380 rplL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L7/L12 YP_002467806.1 44870 R 563178 CDS YP_002467807.1 219681422 7262381 complement(45305..45802) 1 NC_011833.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 45802 rplJ 7262381 rplJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L10 YP_002467807.1 45305 R 563178 CDS YP_002467808.1 219681423 7262382 complement(46068..46763) 1 NC_011833.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 46763 rplA 7262382 rplA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L1 YP_002467808.1 46068 R 563178 CDS YP_002467809.1 219681424 7262383 complement(46766..47194) 1 NC_011833.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 47194 rplK 7262383 rplK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L11 YP_002467809.1 46766 R 563178 CDS YP_002467810.1 219681425 7262384 complement(47242..47787) 1 NC_011833.1 transcription antitermination protein nusG; transcription antitermination protein NusG 47787 nusG 7262384 nusG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription antitermination protein NusG YP_002467810.1 47242 R 563178 CDS YP_002467811.1 219681426 7262385 complement(47790..48173) 1 NC_011833.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 48173 secE 7262385 secE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) preprotein translocase subunit SecE YP_002467811.1 47790 R 563178 CDS YP_002467812.1 219681427 7262733 complement(48978..50048) 1 NC_011833.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 50048 murB 7262733 murB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylenolpyruvoylglucosamine reductase YP_002467812.1 48978 R 563178 CDS YP_002467813.1 219681428 7262734 50164..51042 1 NC_011833.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 51042 metF 7262734 metF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 5,10-methylenetetrahydrofolate reductase YP_002467813.1 50164 D 563178 CDS YP_002467814.1 219681429 7262735 complement(51054..52199) 1 NC_011833.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 52199 argE 7262735 argE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acetylornithine deacetylase YP_002467814.1 51054 R 563178 CDS YP_002467815.1 219681430 7262736 52360..53364 1 NC_011833.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 53364 argC 7262736 argC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) N-acetyl-gamma-glutamyl-phosphate reductase YP_002467815.1 52360 D 563178 CDS YP_002467816.1 219681431 7262737 53385..54158 1 NC_011833.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 54158 argB 7262737 argB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acetylglutamate kinase YP_002467816.1 53385 D 563178 CDS YP_002467817.1 219681432 7262738 54188..55399 1 NC_011833.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 55399 argG 7262738 argG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) argininosuccinate synthase YP_002467817.1 54188 D 563178 CDS YP_002467818.1 219681433 7262739 55471..56850 1 NC_011833.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 56850 argH 7262739 argH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) argininosuccinate lyase YP_002467818.1 55471 D 563178 CDS YP_002467819.1 219681434 7262740 56932..57366 1 NC_011833.1 rhodanese-related sulfurtransferase (YibN) 57366 yibN 7262740 yibN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) rhodanese-related sulfurtransferase (YibN) YP_002467819.1 56932 D 563178 CDS YP_002467820.1 219681435 7262741 57474..57902 1 NC_011833.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 57902 secB 7262741 secB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) preprotein translocase subunit SecB YP_002467820.1 57474 D 563178 CDS YP_002467821.1 219681436 7262742 58004..58828 1 NC_011833.1 serine O-acetyltransferase; serine acetyltransferase 58828 cysE 7262742 cysE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) serine acetyltransferase YP_002467821.1 58004 D 563178 CDS YP_002467822.1 219681437 7262743 complement(58935..60773) 1 NC_011833.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 60773 rpoD 7262743 rpoD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) RNA polymerase sigma factor RpoD YP_002467822.1 58935 R 563178 CDS YP_002467823.1 219681438 7262744 complement(60941..62674) 1 NC_011833.1 DNA primase 62674 dnaG 7262744 dnaG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA primase YP_002467823.1 60941 R 563178 CDS YP_002467824.1 219681439 7262745 complement(62755..62970) 1 NC_011833.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 62970 rpsU 7262745 rpsU Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S21 YP_002467824.1 62755 R 563178 CDS YP_002467825.1 219681440 7262746 63204..64214 1 NC_011833.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 64214 ygjD 7262746 ygjD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative DNA-binding/iron metalloprotein/AP endonuclease YP_002467825.1 63204 D 563178 CDS YP_002467826.1 219681441 7262747 complement(64192..64839) 1 NC_011833.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 64839 ribB 7262747 ribB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_002467826.1 64192 R 563178 CDS YP_002467827.1 219681442 7262748 complement(65112..66059) 1 NC_011833.1 D-alpha,beta-D-heptose 7-phosphate 1-kinase; kinase 66059 yb3052 7262748 yb3052 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) kinase YP_002467827.1 65112 R 563178 CDS YP_002467828.1 219681443 7262749 66273..67517 1 NC_011833.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 67517 cca 7262749 cca Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA CCA-pyrophosphorylase YP_002467828.1 66273 D 563178 CDS YP_002467829.1 219681444 7262750 complement(67543..68340) 1 NC_011833.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 68340 bacA 7262750 bacA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) undecaprenyl pyrophosphate phosphatase YP_002467829.1 67543 R 563178 CDS YP_002467830.1 219681445 7262751 complement(68426..68911) 1 NC_011833.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 68911 crr 7262751 crr Buchnera aphidicola str. 5A (Acyrthosiphon pisum) PTS system glucose-specific transporter YP_002467830.1 68426 R 563178 CDS YP_002467831.1 219681446 7262752 complement(68961..70676) 1 NC_011833.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 70676 ptsI 7262752 ptsI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoenolpyruvate-protein phosphotransferase YP_002467831.1 68961 R 563178 CDS YP_002467832.1 219681447 7262753 complement(70825..71082) 1 NC_011833.1 phosphocarrier protein HPr 71082 ptsH 7262753 ptsH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphocarrier protein HPr YP_002467832.1 70825 R 563178 CDS YP_002467833.1 219681448 7262754 complement(71232..72179) 1 NC_011833.1 cysteine synthase; cysteine synthase A 72179 cysK 7262754 cysK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cysteine synthase A YP_002467833.1 71232 R 563178 CDS YP_002467834.1 219681449 7262755 72434..74461 1 NC_011833.1 DNA ligase 74461 lig 7262755 lig Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA ligase YP_002467834.1 72434 D 563178 CDS YP_002467835.1 219681450 7262758 74773..76176 1 NC_011833.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 76176 gltX 7262758 gltX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutamyl-tRNA synthetase YP_002467835.1 74773 D 563178 CDS YP_002467836.1 219681451 7262760 complement(76516..76812) 1 NC_011833.1 flagellar hook-basal body complex protein FliE 76812 fliE 7262760 fliE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar hook-basal body complex protein FliE YP_002467836.1 76516 R 563178 CDS YP_002467837.1 219681452 7262761 77076..78713 1 NC_011833.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 78713 fliF 7262761 fliF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar MS-ring protein YP_002467837.1 77076 D 563178 CDS YP_002467838.1 219681453 7262762 78710..79705 1 NC_011833.1 flagellar motor switch protein FliG 79705 fliG 7262762 fliG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar motor switch protein FliG YP_002467838.1 78710 D 563178 CDS YP_002467839.1 219681454 7262763 79698..80360 1 NC_011833.1 flagellar assembly protein FliH 80360 fliH 7262763 fliH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar assembly protein FliH YP_002467839.1 79698 D 563178 CDS YP_002467840.1 219681455 7262764 80318..81721 1 NC_011833.1 flagellum-specific ATP synthase 81721 fliI 7262764 fliI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellum-specific ATP synthase YP_002467840.1 80318 D 563178 CDS YP_002467841.1 219681456 7262765 81745..82188 1 NC_011833.1 flagellar FliJ protein 82188 fliJ 7262765 fliJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar FliJ protein YP_002467841.1 81745 D 563178 CDS YP_002467842.1 219681457 7262766 82197..83333 1 NC_011833.1 flagellar hook-length control protein 83333 fliK 7262766 fliK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar hook-length control protein YP_002467842.1 82197 D 563178 CDS YP_002467843.1 219681458 7262767 83394..84341 1 NC_011833.1 flagellar motor switch protein FliM 84341 fliM 7262767 fliM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar motor switch protein FliM YP_002467843.1 83394 D 563178 CDS YP_002467844.1 219681459 7262768 84334..84735 1 NC_011833.1 flagellar motor switch protein FliN 84735 fliN 7262768 fliN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar motor switch protein FliN YP_002467844.1 84334 D 563178 CDS YP_002467845.1 219681460 7262769 84747..85886 1 NC_011833.1 putative bifunctional flagellar biosynthesis protein FliO/FliP 85886 fliP 7262769 fliP Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative bifunctional flagellar biosynthesis protein FliO/FliP YP_002467845.1 84747 D 563178 CDS YP_002467846.1 219681461 7262770 85958..86227 1 NC_011833.1 flagellar biosynthetic protein FliQ 86227 fliQ 7262770 fliQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar biosynthetic protein FliQ YP_002467846.1 85958 D 563178 CDS YP_002467847.1 219681462 7262771 86227..87003 1 NC_011833.1 flagellar biosynthetic protein FliR 87003 fliR 7262771 fliR Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar biosynthetic protein FliR YP_002467847.1 86227 D 563178 CDS YP_002467848.1 219681463 7262772 complement(87156..87323) 1 NC_011833.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 87323 rpmG 7262772 rpmG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L33 YP_002467848.1 87156 R 563178 CDS YP_002467849.1 219681464 7262773 complement(87334..87561) 1 NC_011833.1 required for 70S ribosome assembly; 50S ribosomal protein L28 87561 rpmB 7262773 rpmB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L28 YP_002467849.1 87334 R 563178 CDS YP_002467850.1 219681465 7262774 87907..90819 1 NC_011833.1 hypothetical protein 90819 ytfN 7262774 ytfN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002467850.1 87907 D 563178 CDS YP_002467851.1 219681466 7262775 complement(90835..91383) 1 NC_011833.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 91383 ppa 7262775 ppa Buchnera aphidicola str. 5A (Acyrthosiphon pisum) inorganic pyrophosphatase YP_002467851.1 90835 R 563178 CDS YP_002467852.1 219681467 7262776 91577..92917 1 NC_011833.1 microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62; PmbA protein 92917 pmbA 7262776 pmbA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) PmbA protein YP_002467852.1 91577 D 563178 CDS YP_002467853.1 219681468 7262778 94382..95602 1 NC_011833.1 3-oxoacyl-[acyl-carrier-protein] synthase I; 3-oxoacyl-ACP synthase 95602 fabB 7262778 fabB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-oxoacyl-ACP synthase YP_002467853.1 94382 D 563178 CDS YP_002467854.1 219681469 7262779 95842..96792 1 NC_011833.1 transaldolase; transaldolase B 96792 talA 7262779 talA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transaldolase B YP_002467854.1 95842 D 563178 CDS YP_002467855.1 219681470 7262780 96847..98844 1 NC_011833.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 98844 tktB 7262780 tktB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transketolase YP_002467855.1 96847 D 563178 CDS YP_002467856.1 219681471 7262781 98949..100076 1 NC_011833.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 100076 dapE 7262781 dapE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) succinyl-diaminopimelate desuccinylase YP_002467856.1 98949 D 563178 CDS YP_002467857.1 219681472 7262782 complement(100466..101350) 1 NC_011833.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 101350 dapA 7262782 dapA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydrodipicolinate synthase YP_002467857.1 100466 R 563178 CDS YP_002467858.1 219681473 7262783 complement(101926..102990) 1 NC_011833.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 102990 aroC 7262783 aroC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chorismate synthase YP_002467858.1 101926 R 563178 CDS YP_002467859.1 219681474 7262784 103285..103845 1 NC_011833.1 hypothetical protein 103845 yb2331 7262784 yb2331 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002467859.1 103285 D 563178 CDS YP_002467860.1 219681475 7262785 104170..105069 1 NC_011833.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 105069 hisG 7262785 hisG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP phosphoribosyltransferase YP_002467860.1 104170 D 563178 CDS YP_002467861.1 219681476 7262786 105078..106385 1 NC_011833.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 106385 hisD 7262786 hisD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) histidinol dehydrogenase YP_002467861.1 105078 D 563178 CDS YP_002467862.1 219681477 7262787 106382..107488 1 NC_011833.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 107488 hisC 7262787 hisC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) histidinol-phosphate aminotransferase YP_002467862.1 106382 D 563178 CDS YP_002467863.1 219681478 7262788 107478..108539 1 NC_011833.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 108539 hisB 7262788 hisB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) imidazole glycerol-phosphate dehydratase/histidinol phosphatase YP_002467863.1 107478 D 563178 CDS YP_002467864.1 219681479 7262789 108539..109129 1 NC_011833.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 109129 hisH 7262789 hisH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) imidazole glycerol phosphate synthase subunit HisH YP_002467864.1 108539 D 563178 CDS YP_002467865.1 219681480 7262790 109134..109874 1 NC_011833.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 109874 hisA 7262790 hisA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase YP_002467865.1 109134 D 563178 CDS YP_002467866.1 219681481 7262791 109853..110629 1 NC_011833.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 110629 hisF 7262791 hisF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) imidazole glycerol phosphate synthase subunit HisF YP_002467866.1 109853 D 563178 CDS YP_002467867.1 219681482 7262792 110623..111270 1 NC_011833.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 111270 hisI 7262792 hisI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase YP_002467867.1 110623 D 563178 CDS YP_002467868.1 219681483 7262793 111629..113035 1 NC_011833.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 113035 gnd 7262793 gnd Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 6-phosphogluconate dehydrogenase YP_002467868.1 111629 D 563178 CDS YP_002467869.1 219681484 7262794 113198..113818 1 NC_011833.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 113818 dcd 7262794 dcd Buchnera aphidicola str. 5A (Acyrthosiphon pisum) deoxycytidine triphosphate deaminase YP_002467869.1 113198 D 563178 CDS YP_002467870.1 219681485 7262795 113966..115609 1 NC_011833.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 115609 metG 7262795 metG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) methionyl-tRNA synthetase YP_002467870.1 113966 D 563178 CDS YP_002467871.1 219681486 7262796 complement(115657..116979) 1 NC_011833.1 cell cycle protein MesJ 116979 mesJ 7262796 mesJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell cycle protein MesJ YP_002467871.1 115657 R 563178 CDS YP_002467872.1 219681487 7262798 117205..117831 1 NC_011833.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 117831 ribE 7262798 ribE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) riboflavin synthase subunit alpha YP_002467872.1 117205 D 563178 CDS YP_002467873.1 219681488 7262799 117868..118449 1 NC_011833.1 Na(+)-translocating NADH-quinone reductase subunit E 118449 rnfA 7262799 rnfA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) Na(+)-translocating NADH-quinone reductase subunit E YP_002467873.1 117868 D 563178 CDS YP_002467874.1 219681489 7262800 118452..118955 1 NC_011833.1 ferredoxin II 118955 rnfB 7262800 rnfB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ferredoxin II YP_002467874.1 118452 D 563178 CDS YP_002467875.1 219681490 7262801 119118..120539 1 NC_011833.1 membrane protein 120539 rnfC 7262801 rnfC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) membrane protein YP_002467875.1 119118 D 563178 CDS YP_002467876.1 219681491 7262802 120587..121630 1 NC_011833.1 hypothetical protein 121630 ydgO 7262802 ydgO Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002467876.1 120587 D 563178 CDS YP_002467877.1 219681492 7262803 121779..122273 1 NC_011833.1 nitrogen fixation protein 122273 rnfG 7262803 rnfG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) nitrogen fixation protein YP_002467877.1 121779 D 563178 CDS YP_002467878.1 219681493 7262804 122248..122931 1 NC_011833.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 122931 ydgQ 7262804 ydgQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) electron transport complex protein RsxE YP_002467878.1 122248 D 563178 CDS YP_002467879.1 219681494 7262805 122942..123574 1 NC_011833.1 endonuclease III 123574 nth 7262805 nth Buchnera aphidicola str. 5A (Acyrthosiphon pisum) endonuclease III YP_002467879.1 122942 D 563178 CDS YP_002467880.1 219681495 7262806 123597..125777 1 NC_011833.1 replication restart DNA helicase PriA; primosomal protein N' 125777 priA 7262806 priA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) primosomal protein N' YP_002467880.1 123597 D 563178 CDS YP_002467881.1 219681496 7262807 125937..127205 1 NC_011833.1 tyrosyl-tRNA synthetase 127205 tyrS 7262807 tyrS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tyrosyl-tRNA synthetase YP_002467881.1 125937 D 563178 CDS YP_002467882.1 219681497 7262808 complement(127213..127605) 1 NC_011833.1 integral membrane protein of SoxR-reducing complex 127605 ydiC 7262808 ydiC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) integral membrane protein of SoxR-reducing complex YP_002467882.1 127213 R 563178 CDS YP_002467883.1 219681498 7262809 127829..128911 1 NC_011833.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 128911 yb1688 7262809 yb1688 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative inner membrane protein YP_002467883.1 127829 D 563178 CDS YP_002467884.1 219681499 7262810 129263..130309 1 NC_011833.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 130309 aroH 7262810 aroH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phospho-2-dehydro-3-deoxyheptonate aldolase YP_002467884.1 129263 D 563178 CDS YP_002467885.1 219681500 7262812 130477..132405 1 NC_011833.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 132405 thrS 7262812 thrS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) threonyl-tRNA synthetase YP_002467885.1 130477 D 563178 CDS YP_002467886.1 219681501 7262634 132409..132948 1 NC_011833.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 132948 infC 7262634 infC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) translation initiation factor IF-3 YP_002467886.1 132409 D 563178 CDS YP_002467887.1 219681502 7262635 133035..133232 1 NC_011833.1 LSU ribosomal protein L35P; 50S ribosomal protein L35 133232 rpmI 7262635 rpmI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L35 YP_002467887.1 133035 D 563178 CDS YP_002467888.1 219681503 7262636 133275..133631 1 NC_011833.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 133631 rplT 7262636 rplT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L20 YP_002467888.1 133275 D 563178 CDS YP_002467889.1 219681504 7262637 133826..134815 1 NC_011833.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 134815 pheS 7262637 pheS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phenylalanyl-tRNA synthetase subunit alpha YP_002467889.1 133826 D 563178 CDS YP_002467890.1 219681505 7262638 134825..137212 1 NC_011833.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 137212 pheT 7262638 pheT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phenylalanyl-tRNA synthetase subunit beta YP_002467890.1 134825 D 563178 CDS YP_002467891.1 219681506 7262639 137217..137525 1 NC_011833.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 137525 ihfA 7262639 ihfA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) integration host factor subunit alpha YP_002467891.1 137217 D 563178 CDS YP_002467892.1 219681507 7262640 137567..138640 1 NC_011833.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 138640 queA 7262640 queA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) S-adenosylmethionine--tRNA ribosyltransferase-isomerase YP_002467892.1 137567 D 563178 CDS YP_002467893.1 219681508 7262641 138681..139793 1 NC_011833.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 139793 tgt 7262641 tgt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) queuine tRNA-ribosyltransferase YP_002467893.1 138681 D 563178 CDS YP_002467894.1 219681509 7262642 139818..140153 1 NC_011833.1 protein translocase subunit YajC; subunit of SecD-SecF-Yajc-YidC secretion complex 140153 yajC 7262642 yajC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) subunit of SecD-SecF-Yajc-YidC secretion complex YP_002467894.1 139818 D 563178 CDS YP_002467895.1 219681510 7262643 complement(140205..142277) 1 NC_011833.1 glycyl-tRNA synthetase subunit beta 142277 glyS 7262643 glyS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glycyl-tRNA synthetase subunit beta YP_002467895.1 140205 R 563178 CDS YP_002467896.1 219681511 7262644 complement(142252..143190) 1 NC_011833.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 143190 glyQ 7262644 glyQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glycyl-tRNA synthetase subunit alpha YP_002467896.1 142252 R 563178 CDS YP_002467897.1 219681512 7262645 143886..144731 1 NC_011833.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 144731 nfo 7262645 nfo Buchnera aphidicola str. 5A (Acyrthosiphon pisum) endonuclease IV YP_002467897.1 143886 D 563178 CDS YP_002467898.1 219681513 7262646 144766..145053 1 NC_011833.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 145053 rplY 7262646 rplY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L25 YP_002467898.1 144766 D 563178 CDS YP_002467899.1 219681514 7262647 complement(145123..145893) 1 NC_011833.1 hypothetical protein 145893 yabI 7262647 yabI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002467899.1 145123 R 563178 CDS YP_002467900.1 219681515 7262648 146080..147372 1 NC_011833.1 survival protein SurA 147372 surA 7262648 surA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) survival protein SurA YP_002467900.1 146080 D 563178 CDS YP_002467901.1 219681516 7262649 147426..148247 1 NC_011833.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 148247 ksgA 7262649 ksgA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dimethyladenosine transferase YP_002467901.1 147426 D 563178 CDS YP_002467902.1 219681517 7262650 148292..149116 1 NC_011833.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 149116 apaH 7262650 apaH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) diadenosine tetraphosphatase YP_002467902.1 148292 D 563178 CDS YP_002467903.1 219681518 7262651 complement(149143..149628) 1 NC_011833.1 dihydrofolate reductase 149628 folA 7262651 folA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydrofolate reductase YP_002467903.1 149143 R 563178 CDS YP_002467904.1 219681519 7262652 complement(149718..152957) 1 NC_011833.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 152957 carB 7262652 carB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) carbamoyl phosphate synthase large subunit YP_002467904.1 149718 R 563178 CDS YP_002467905.1 219681520 7262653 complement(152971..154134) 1 NC_011833.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 154134 carA 7262653 carA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) carbamoyl phosphate synthase small subunit YP_002467905.1 152971 R 563178 CDS YP_002467906.1 219681521 7262654 complement(154344..155153) 1 NC_011833.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 155153 dapB 7262654 dapB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydrodipicolinate reductase YP_002467906.1 154344 R 563178 CDS YP_002467907.1 219681522 7262655 complement(155157..156116) 1 NC_011833.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 156116 ispH 7262655 ispH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_002467907.1 155157 R 563178 CDS YP_002467908.1 219681523 7262656 complement(156181..156663) 1 NC_011833.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 156663 lspA 7262656 lspA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lipoprotein signal peptidase YP_002467908.1 156181 R 563178 CDS YP_002467909.1 219681524 7262657 complement(156663..159485) 1 NC_011833.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 159485 ileS 7262657 ileS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) isoleucyl-tRNA synthetase YP_002467909.1 156663 R 563178 CDS YP_002467910.1 219681525 7262658 complement(159502..160443) 1 NC_011833.1 FMN adenylyltransferase 160443 ribF 7262658 ribF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) FMN adenylyltransferase YP_002467910.1 159502 R 563178 CDS YP_002467911.1 219681526 7262659 160658..160927 1 NC_011833.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 160927 rpsT 7262659 rpsT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S20 YP_002467911.1 160658 D 563178 CDS YP_002467912.1 219681527 7262660 complement(160977..162110) 1 NC_011833.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 162110 dnaJ 7262660 dnaJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chaperone protein DnaJ YP_002467912.1 160977 R 563178 CDS YP_002467913.1 219681528 7262661 complement(162223..164136) 1 NC_011833.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 164136 dnaK 7262661 dnaK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) molecular chaperone DnaK YP_002467913.1 162223 R 563178 CDS YP_002467914.1 219681529 7262662 164472..164876 1 NC_011833.1 NADH dehydrogenase I subunit A 164876 nuoA 7262662 nuoA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit A YP_002467914.1 164472 D 563178 CDS YP_002467915.1 219681530 7262663 164910..165584 1 NC_011833.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 165584 nuoB 7262663 nuoB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase subunit B YP_002467915.1 164910 D 563178 CDS YP_002467916.1 219681531 7262664 165675..167477 1 NC_011833.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 167477 nuoCD 7262664 nuoCD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional NADH:ubiquinone oxidoreductase subunit C/D YP_002467916.1 165675 D 563178 CDS YP_002467917.1 219681532 7262665 167500..167988 1 NC_011833.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 167988 nuoE 7262665 nuoE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase subunit E YP_002467917.1 167500 D 563178 CDS YP_002467918.1 219681533 7262666 167985..169319 1 NC_011833.1 NADH dehydrogenase I subunit F 169319 nuoF 7262666 nuoF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit F YP_002467918.1 167985 D 563178 CDS YP_002467919.1 219681534 7262667 169413..172133 1 NC_011833.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 172133 nuoG 7262667 nuoG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase subunit G YP_002467919.1 169413 D 563178 CDS YP_002467920.1 219681535 7262668 172145..173113 1 NC_011833.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 173113 nuoH 7262668 nuoH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase subunit H YP_002467920.1 172145 D 563178 CDS YP_002467921.1 219681536 7262669 173138..173680 1 NC_011833.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 173680 nuoI 7262669 nuoI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase subunit I YP_002467921.1 173138 D 563178 CDS YP_002467922.1 219681537 7262670 173690..174202 1 NC_011833.1 NADH dehydrogenase I subunit J 174202 nuoJ 7262670 nuoJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit J YP_002467922.1 173690 D 563178 CDS YP_002467923.1 219681538 7262671 174233..174535 1 NC_011833.1 NADH dehydrogenase I subunit K 174535 nuoK 7262671 nuoK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit K YP_002467923.1 174233 D 563178 CDS YP_002467924.1 219681539 7262672 174532..176376 1 NC_011833.1 NADH dehydrogenase I subunit L 176376 nuoL 7262672 nuoL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit L YP_002467924.1 174532 D 563178 CDS YP_002467925.1 219681540 7262673 176473..177990 1 NC_011833.1 NADH dehydrogenase I subunit M 177990 nuoM 7262673 nuoM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit M YP_002467925.1 176473 D 563178 CDS YP_002467926.1 219681541 7262674 178048..179457 1 NC_011833.1 NADH dehydrogenase I subunit N 179457 nuoN 7262674 nuoN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NADH dehydrogenase I subunit N YP_002467926.1 178048 D 563178 CDS YP_002467927.1 219681542 7262675 180582..181817 1 NC_011833.1 dihydrofolate synthase 181817 folC 7262675 folC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydrofolate synthase YP_002467927.1 180582 D 563178 CDS YP_002467928.1 219681543 7262676 complement(182396..183343) 1 NC_011833.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 183343 prsA 7262676 prsA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribose-phosphate pyrophosphokinase YP_002467928.1 182396 R 563178 CDS YP_002467929.1 219681544 7262677 complement(183463..184347) 1 NC_011833.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 184347 ipk 7262677 ipk Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_002467929.1 183463 R 563178 CDS YP_002467930.1 219681545 7262678 184555..185640 1 NC_011833.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 185640 prfA 7262678 prfA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptide chain release factor 1 YP_002467930.1 184555 D 563178 CDS YP_002467931.1 219681546 7262679 185637..186470 1 NC_011833.1 HemK protein 186470 hemK 7262679 hemK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) HemK protein YP_002467931.1 185637 D 563178 CDS YP_002467932.1 219681547 7262680 186630..187439 1 NC_011833.1 transcriptional regulator; putative transcriptional regulator 187439 ychA 7262680 ychA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative transcriptional regulator YP_002467932.1 186630 D 563178 CDS YP_002467933.1 219681548 7262681 complement(187447..188253) 1 NC_011833.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 188253 nadE 7262681 nadE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) NAD synthetase YP_002467933.1 187447 R 563178 CDS YP_002467934.1 219681549 7262682 188337..189554 1 NC_011833.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 189554 ackA 7262682 ackA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acetate kinase YP_002467934.1 188337 D 563178 CDS YP_002467935.1 219681550 7262683 189599..191725 1 NC_011833.1 phosphotransacetylase; phosphate acetyltransferase 191725 pta 7262683 pta Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphate acetyltransferase YP_002467935.1 189599 D 563178 CDS YP_002467936.1 219681551 7262684 complement(191757..192020) 1 NC_011833.1 diferric-tyrosyl radical cofactor maintenance protein 192020 yfaE 7262684 yfaE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) diferric-tyrosyl radical cofactor maintenance protein YP_002467936.1 191757 R 563178 CDS YP_002467937.1 219681552 7262685 complement(192023..193153) 1 NC_011833.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 193153 nrdB 7262685 nrdB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribonucleotide-diphosphate reductase subunit beta YP_002467937.1 192023 R 563178 CDS YP_002467938.1 219681553 7262686 complement(193221..195506) 1 NC_011833.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 195506 nrdA 7262686 nrdA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribonucleotide-diphosphate reductase subunit alpha YP_002467938.1 193221 R 563178 CDS YP_002467939.1 219681554 7262687 complement(195579..198071) 1 NC_011833.1 DNA gyrase subunit A 198071 gyrA 7262687 gyrA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA gyrase subunit A YP_002467939.1 195579 R 563178 CDS YP_002467940.1 219681555 7262688 198338..199054 1 NC_011833.1 hypothetical protein 199054 yba2 7262688 yba2 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002467940.1 198338 D 563178 CDS YP_002467941.1 219681556 7262689 complement(199176..199769) 1 NC_011833.1 alkyl hydroperoxide reductase 199769 ahpC 7262689 ahpC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) alkyl hydroperoxide reductase YP_002467941.1 199176 R 563178 CDS YP_002467942.1 219681557 7262691 complement(200583..201149) 1 NC_011833.1 heat shock protein GrpE2 201149 grpE 7262691 grpE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) heat shock protein GrpE2 YP_002467942.1 200583 R 563178 CDS YP_002467943.1 219681558 7262692 201266..202144 1 NC_011833.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 202144 ppnK 7262692 ppnK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) inorganic polyphosphate/ATP-NAD kinase YP_002467943.1 201266 D 563178 CDS YP_002467944.1 219681559 7262693 202277..202585 1 NC_011833.1 small protein A 202585 smpA 7262693 smpA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) small protein A YP_002467944.1 202277 D 563178 CDS YP_002467945.1 219681944 7262695 203122..203448 1 NC_011833.1 glutaredoxin 203448 grxD 7262695 grxD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutaredoxin YP_002467945.1 203122 D 563178 CDS YP_002467946.1 219681560 7262728 complement(203592..204257) 1 NC_011833.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 204257 rnt 7262728 rnt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribonuclease T YP_002467946.1 203592 R 563178 CDS YP_002467947.1 219681561 7262696 204477..205088 1 NC_011833.1 superoxide dismutase 205088 sodA 7262696 sodA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) superoxide dismutase YP_002467947.1 204477 D 563178 CDS YP_002467948.1 219681562 7262697 205276..205809 1 NC_011833.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 205809 pth 7262697 pth Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptidyl-tRNA hydrolase YP_002467948.1 205276 D 563178 CDS YP_002467949.1 219681563 7262698 205850..206938 1 NC_011833.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 206938 ychF 7262698 ychF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP-dependent nucleic acid-binding protein EngD YP_002467949.1 205850 D 563178 CDS YP_002467950.1 219681564 7262699 complement(207014..208303) 1 NC_011833.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 208303 thrC 7262699 thrC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) threonine synthase YP_002467950.1 207014 R 563178 CDS YP_002467951.1 219681565 7262700 complement(208310..209239) 1 NC_011833.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 209239 thrB 7262700 thrB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) homoserine kinase YP_002467951.1 208310 R 563178 CDS YP_002467952.1 219681566 7262701 complement(209260..211710) 1 NC_011833.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 211710 thrA 7262701 thrA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional aspartokinase I/homoserine dehydrogenase I YP_002467952.1 209260 R 563178 CDS YP_002467953.1 219681567 7262702 212369..212905 1 NC_011833.1 hypoxanthine phosphoribosyltransferase 212905 hpt 7262702 hpt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypoxanthine phosphoribosyltransferase YP_002467953.1 212369 D 563178 CDS YP_002467954.1 219681568 7262703 complement(212913..213770) 1 NC_011833.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 213770 panC 7262703 panC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) pantoate--beta-alanine ligase YP_002467954.1 212913 R 563178 CDS YP_002467955.1 219681569 7262704 complement(213785..214576) 1 NC_011833.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 214576 panB 7262704 panB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_002467955.1 213785 R 563178 CDS YP_002467956.1 219681570 7262705 complement(214692..215147) 1 NC_011833.1 DnaK suppressor protein 215147 dksA 7262705 dksA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DnaK suppressor protein YP_002467956.1 214692 R 563178 CDS YP_002467957.1 219681571 7262706 215404..216204 1 NC_011833.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 216204 truA 7262706 truA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA pseudouridine synthase A YP_002467957.1 215404 D 563178 CDS YP_002467958.1 219681572 7262707 216276..218558 1 NC_011833.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; penicillin-binding protein 1b 218558 mrcB 7262707 mrcB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) penicillin-binding protein 1b YP_002467958.1 216276 D 563178 CDS YP_002467959.1 219681573 7262708 218788..221415 1 NC_011833.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 221415 secA 7262708 secA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) preprotein translocase subunit SecA YP_002467959.1 218788 D 563178 CDS YP_002467960.1 219681574 7262709 221491..221865 1 NC_011833.1 mutator MutT protein 221865 mutT 7262709 mutT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) mutator MutT protein YP_002467960.1 221491 D 563178 CDS YP_002467961.1 219681575 7262710 complement(221848..222501) 1 NC_011833.1 Dephospho-CoA kinase; dephospho-CoA kinase 222501 yacE 7262710 yacE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dephospho-CoA kinase YP_002467961.1 221848 R 563178 CDS YP_002467962.1 219681576 7262711 222557..223606 1 NC_011833.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 223606 guaC 7262711 guaC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) guanosine 5'-monophosphate oxidoreductase YP_002467962.1 222557 D 563178 CDS YP_002467963.1 219681577 7262712 223834..226497 1 NC_011833.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 226497 aceE 7262712 aceE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) pyruvate dehydrogenase subunit E1 YP_002467963.1 223834 D 563178 CDS YP_002467964.1 219681578 7262387 226501..227718 1 NC_011833.1 branched-chain alpha-keto acid dehydrogenase subunit E2 227718 aceF 7262387 aceF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) branched-chain alpha-keto acid dehydrogenase subunit E2 YP_002467964.1 226501 D 563178 CDS YP_002467965.1 219681579 7262469 227762..229183 1 NC_011833.1 dihydrolipoamide dehydrogenase 229183 lpdA 7262469 lpdA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydrolipoamide dehydrogenase YP_002467965.1 227762 D 563178 CDS YP_002467966.1 219681580 7262470 complement(229356..230153) 1 NC_011833.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 230153 speD 7262470 speD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) S-adenosylmethionine decarboxylase YP_002467966.1 229356 R 563178 CDS YP_002467967.1 219681581 7262471 complement(230172..231032) 1 NC_011833.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 231032 speE 7262471 speE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) spermidine synthase YP_002467967.1 230172 R 563178 CDS YP_002467968.1 219681582 7262472 complement(231308..232006) 1 NC_011833.1 methylthioadenosine nucleosidase; 5'-methylthioadenosine nucleosidase 232006 pfs 7262472 pfs Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 5'-methylthioadenosine nucleosidase YP_002467968.1 231308 R 563178 CDS YP_002467969.1 219681583 7262473 complement(232070..232414) 1 NC_011833.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 232414 yadR 7262473 yadR Buchnera aphidicola str. 5A (Acyrthosiphon pisum) iron-sulfur cluster insertion protein ErpA YP_002467969.1 232070 R 563178 CDS YP_002467970.1 219681584 7262474 complement(232648..233802) 1 NC_011833.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 233802 ftsZ 7262474 ftsZ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsZ YP_002467970.1 232648 R 563178 CDS YP_002467971.1 219681585 7262475 complement(233860..235116) 1 NC_011833.1 cell division protein FtsA 235116 ftsA 7262475 ftsA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsA YP_002467971.1 233860 R 563178 CDS YP_002467972.1 219681586 7262476 complement(236231..237685) 1 NC_011833.1 UDP-N-acetylmuramate--L-alanine ligase; UDP-N-acetylmuramate-alanine ligase 237685 murC 7262476 murC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylmuramate-alanine ligase YP_002467972.1 236231 R 563178 CDS YP_002467973.1 219681587 7262477 complement(237728..238792) 1 NC_011833.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 238792 murG 7262477 murG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase YP_002467973.1 237728 R 563178 CDS YP_002467974.1 219681588 7262478 complement(238789..239988) 1 NC_011833.1 cell division protein FtsW 239988 ftsW 7262478 ftsW Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsW YP_002467974.1 238789 R 563178 CDS YP_002467975.1 219681589 7262479 complement(239985..241307) 1 NC_011833.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 241307 murD 7262479 murD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase YP_002467975.1 239985 R 563178 CDS YP_002467976.1 219681590 7262480 complement(241307..242380) 1 NC_011833.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 242380 mraY 7262480 mraY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phospho-N-acetylmuramoyl-pentapeptide- transferase YP_002467976.1 241307 R 563178 CDS YP_002467977.1 219681591 7262481 complement(242364..243740) 1 NC_011833.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 243740 murF 7262481 murF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase YP_002467977.1 242364 R 563178 CDS YP_002467978.1 219681592 7262482 complement(243737..245233) 1 NC_011833.1 UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase 245233 murE 7262482 murE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase YP_002467978.1 243737 R 563178 CDS YP_002467979.1 219681593 7262483 complement(245234..246973) 1 NC_011833.1 peptidoglycan synthetase FtsI; cell division protein FtsI 246973 ftsI 7262483 ftsI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsI YP_002467979.1 245234 R 563178 CDS YP_002467980.1 219681594 7262484 complement(join(247038..247118,247118..247291)) 1 NC_011833.1 cell division protein 247291 ftsL 7262484 ftsL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein YP_002467980.1 247038 R 563178 CDS YP_002467981.1 219681595 7262485 complement(247294..248232) 1 NC_011833.1 S-adenosyl-methyltransferase MraW 248232 mraW 7262485 mraW Buchnera aphidicola str. 5A (Acyrthosiphon pisum) S-adenosyl-methyltransferase MraW YP_002467981.1 247294 R 563178 CDS YP_002467982.1 219681596 7262486 complement(248354..248830) 1 NC_011833.1 acetolactate synthase, small subunit; acetolactate synthase small subunit 248830 ilvH 7262486 ilvH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acetolactate synthase small subunit YP_002467982.1 248354 R 563178 CDS YP_002467983.1 219681597 7262487 complement(248835..250550) 1 NC_011833.1 acetolactate synthase, large subunit; acetolactate synthase large subunit 250550 ilvI 7262487 ilvI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acetolactate synthase large subunit YP_002467983.1 248835 R 563178 CDS YP_002467984.1 219681598 7262488 252168..253604 1 NC_011833.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 253604 htrA 7262488 htrA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) serine endoprotease YP_002467984.1 252168 D 563178 CDS YP_002467985.1 219681599 7262489 complement(253648..254472) 1 NC_011833.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 254472 dapD 7262489 dapD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_002467985.1 253648 R 563178 CDS YP_002467986.1 219681600 7262490 complement(254533..255327) 1 NC_011833.1 methionine aminopeptidase, type I; methionine aminopeptidase 255327 map 7262490 map Buchnera aphidicola str. 5A (Acyrthosiphon pisum) methionine aminopeptidase YP_002467986.1 254533 R 563178 CDS YP_002467987.1 219681601 7262491 255590..256324 1 NC_011833.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 256324 rpsB 7262491 rpsB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S2 YP_002467987.1 255590 D 563178 CDS YP_002467988.1 219681602 7262492 256401..257207 1 NC_011833.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 257207 tsf 7262492 tsf Buchnera aphidicola str. 5A (Acyrthosiphon pisum) elongation factor Ts YP_002467988.1 256401 D 563178 CDS YP_002467989.1 219681603 7262493 257258..257986 1 NC_011833.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 257986 pyrH 7262493 pyrH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) uridylate kinase YP_002467989.1 257258 D 563178 CDS YP_002467990.1 219681604 7262494 258066..258623 1 NC_011833.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 258623 frr 7262494 frr Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribosome recycling factor YP_002467990.1 258066 D 563178 CDS YP_002467991.1 219681605 7262495 258706..259902 1 NC_011833.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 259902 dxr 7262495 dxr Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_002467991.1 258706 D 563178 CDS YP_002467992.1 219681606 7262496 259995..260750 1 NC_011833.1 Undecaprenyl pyrophosphate synthetase; undecaprenyl pyrophosphate synthetase 260750 uppS 7262496 uppS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) undecaprenyl pyrophosphate synthetase YP_002467992.1 259995 D 563178 CDS YP_002467993.1 219681607 7262497 260984..263386 1 NC_011833.1 component of outer membrane protein assembly complex; YaeT 263386 yaeT 7262497 yaeT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) YaeT YP_002467993.1 260984 D 563178 CDS YP_002467994.1 219681608 7262498 263513..263968 1 NC_011833.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 263968 fabZ 7262498 fabZ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) (3R)-hydroxymyristoyl-ACP dehydratase YP_002467994.1 263513 D 563178 CDS YP_002467995.1 219681609 7262499 264005..267490 1 NC_011833.1 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 267490 dnaE 7262499 dnaE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III subunit alpha YP_002467995.1 264005 D 563178 CDS YP_002467996.1 219681610 7262500 complement(267618..269336) 1 NC_011833.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 269336 proS 7262500 proS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) prolyl-tRNA synthetase YP_002467996.1 267618 R 563178 CDS YP_002467997.1 219681611 7262501 269677..270828 1 NC_011833.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 270828 flhB 7262501 flhB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar biosynthesis protein FlhB YP_002467997.1 269677 D 563178 CDS YP_002467998.1 219681612 7262502 270821..272911 1 NC_011833.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 272911 flhA 7262502 flhA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar biosynthesis protein FlhA YP_002467998.1 270821 D 563178 CDS YP_002467999.1 219681613 7262503 complement(273035..274759) 1 NC_011833.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 274759 argS 7262503 argS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) arginyl-tRNA synthetase YP_002467999.1 273035 R 563178 CDS YP_002468000.1 219681614 7262507 complement(276943..277698) 1 NC_011833.1 hydroxyacylglutathione hydrolase 277698 gloB 7262507 gloB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hydroxyacylglutathione hydrolase YP_002468000.1 276943 R 563178 CDS YP_002468001.1 219681615 7262508 278261..278974 1 NC_011833.1 DNA polymerase III, epsilon subunit; DNA polymerase III subunit epsilon 278974 dnaQ 7262508 dnaQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III subunit epsilon YP_002468001.1 278261 D 563178 CDS YP_002468002.1 219681616 7262510 279200..279781 1 NC_011833.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 279781 gmhA 7262510 gmhA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoheptose isomerase YP_002468002.1 279200 D 563178 CDS YP_002468003.1 219681617 7262511 279888..280364 1 NC_011833.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 280364 gpt 7262511 gpt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) xanthine-guanine phosphoribosyltransferase YP_002468003.1 279888 D 563178 CDS YP_002468004.1 219681618 7262512 280466..281050 1 NC_011833.1 heat shock protein GrpE1 281050 grpE1 7262512 grpE1 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) heat shock protein GrpE1 YP_002468004.1 280466 D 563178 CDS YP_002468005.1 219681619 7262513 complement(281129..281428) 1 NC_011833.1 hypothetical protein 281428 yfjF 7262513 yfjF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468005.1 281129 R 563178 CDS YP_002468006.1 219681620 7262514 281522..282010 1 NC_011833.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 282010 smpB 7262514 smpB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) SsrA-binding protein YP_002468006.1 281522 D 563178 CDS YP_002468007.1 219681621 7262515 282019..282504 1 NC_011833.1 tRNA-adenosine deaminase; hypothetical protein YfhC 282504 yfhC 7262515 yfhC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YfhC YP_002468007.1 282019 D 563178 CDS YP_002468008.1 219681622 7262516 complement(282505..282885) 1 NC_011833.1 holo-[acyl-carrier protein] synthase 282885 acpS 7262516 acpS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) holo-[acyl-carrier protein] synthase YP_002468008.1 282505 R 563178 CDS YP_002468009.1 219681623 7262517 complement(283011..283862) 1 NC_011833.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 283862 era 7262517 era Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP-binding protein Era YP_002468009.1 283011 R 563178 CDS YP_002468010.1 219681624 7262518 complement(283859..284539) 1 NC_011833.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 284539 rnc 7262518 rnc Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribonuclease III YP_002468010.1 283859 R 563178 CDS YP_002468011.1 219681625 7262519 complement(284670..285614) 1 NC_011833.1 signal peptidase I . Serine peptidase. MEROPS family S26A; signal peptidase I 285614 lepB 7262519 lepB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) signal peptidase I YP_002468011.1 284670 R 563178 CDS YP_002468012.1 219681626 7262520 complement(285630..287462) 1 NC_011833.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 287462 lepA 7262520 lepA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP-binding protein LepA YP_002468012.1 285630 R 563178 CDS YP_002468013.1 219681627 7262521 287658..288764 1 NC_011833.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 288764 mnmA 7262521 mnmA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA-specific 2-thiouridylase MnmA YP_002468013.1 287658 D 563178 CDS YP_002468014.1 219681628 7262522 288800..289435 1 NC_011833.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 289435 ycfC 7262522 ycfC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468014.1 288800 D 563178 CDS YP_002468015.1 219681629 7262523 289474..290844 1 NC_011833.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 290844 purB 7262523 purB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) adenylosuccinate lyase YP_002468015.1 289474 D 563178 CDS YP_002468016.1 219681630 7262524 290868..291533 1 NC_011833.1 membrane-bound lytic murein transglycosylase E 291533 mltE 7262524 mltE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) membrane-bound lytic murein transglycosylase E YP_002468016.1 290868 D 563178 CDS YP_002468017.1 219681631 7262525 291647..292429 1 NC_011833.1 Enoyl-[acyl-carrier-protein] reductase [NADH]; enoyl-[acyl-carrier-protein] reductase (NADH) 292429 fabI 7262525 fabI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) enoyl-[acyl-carrier-protein] reductase (NADH) YP_002468017.1 291647 D 563178 CDS YP_002468018.1 219681632 7262526 292616..294565 1 NC_011833.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 294565 rnb 7262526 rnb Buchnera aphidicola str. 5A (Acyrthosiphon pisum) exoribonuclease II YP_002468018.1 292616 D 563178 CDS YP_002468019.1 219681633 7262527 294673..295320 1 NC_011833.1 hypothetical protein 295320 ychE 7262527 ychE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468019.1 294673 D 563178 CDS YP_002468020.1 219681634 7262528 295358..295993 1 NC_011833.1 lipoate-protein ligase B 295993 lipB 7262528 lipB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lipoate-protein ligase B YP_002468020.1 295358 D 563178 CDS YP_002468021.1 219681635 7262529 296113..297084 1 NC_011833.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 297084 lipA 7262529 lipA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lipoyl synthase YP_002468021.1 296113 D 563178 CDS YP_002468022.1 219681636 7262530 297189..297899 1 NC_011833.1 orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 297899 pyrF 7262530 pyrF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) orotidine 5'-phosphate decarboxylase YP_002468022.1 297189 D 563178 CDS YP_002468023.1 219681637 7262531 297947..298531 1 NC_011833.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 298531 ribA 7262531 ribA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP cyclohydrolase II YP_002468023.1 297947 D 563178 CDS YP_002468024.1 219681638 7262532 complement(298635..299042) 1 NC_011833.1 nucleoid protein H-NS; DNA-binding protein H-ns 299042 hns 7262532 hns Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA-binding protein H-ns YP_002468024.1 298635 R 563178 CDS YP_002468025.1 219681639 7262533 complement(299388..300848) 1 NC_011833.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 300848 cls 7262533 cls Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cardiolipin synthetase YP_002468025.1 299388 R 563178 CDS YP_002468026.1 219681640 7262534 complement(301229..301636) 1 NC_011833.1 acyl-CoA thioesterase (YciA) 301636 yciA 7262534 yciA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acyl-CoA thioesterase (YciA) YP_002468026.1 301229 R 563178 CDS YP_002468027.1 219681641 7262535 complement(301673..302206) 1 NC_011833.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 302206 yciB 7262535 yciB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) intracellular septation protein A YP_002468027.1 301673 R 563178 CDS YP_002468028.1 219681642 7262536 complement(302234..302977) 1 NC_011833.1 hypothetical protein 302977 yciC 7262536 yciC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468028.1 302234 R 563178 CDS YP_002468029.1 219681643 7262537 complement(303082..303891) 1 NC_011833.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 303891 trpA 7262537 trpA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tryptophan synthase subunit alpha YP_002468029.1 303082 R 563178 CDS YP_002468030.1 219681644 7262539 complement(305115..306476) 1 NC_011833.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 306476 trpC 7262539 trpC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase YP_002468030.1 305115 R 563178 CDS YP_002468031.1 219681645 7262540 complement(306457..307485) 1 NC_011833.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 307485 trpD 7262540 trpD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) anthranilate phosphoribosyltransferase YP_002468031.1 306457 R 563178 CDS YP_002468032.1 219681646 7262541 307720..308643 1 NC_011833.1 hypothetical protein 308643 yedA 7262541 yedA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468032.1 307720 D 563178 CDS YP_002468033.1 219681647 7262542 308672..309424 1 NC_011833.1 ribosomal large subunit pseudouridine synthase B; 23S rRNA pseudouridine synthase (YciL) 309424 yciL 7262542 yciL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 23S rRNA pseudouridine synthase (YciL) YP_002468033.1 308672 D 563178 CDS YP_002468034.1 219681648 7262543 309499..310509 1 NC_011833.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 310509 sohB 7262543 sohB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative periplasmic protease YP_002468034.1 309499 D 563178 CDS YP_002468035.1 219681649 7262544 310595..313180 1 NC_011833.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 313180 topA 7262544 topA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA topoisomerase I YP_002468035.1 310595 D 563178 CDS YP_002468036.1 219681650 7262545 complement(313232..314032) 1 NC_011833.1 extragenic suppressor protein SuhB 314032 suhB 7262545 suhB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) extragenic suppressor protein SuhB YP_002468036.1 313232 R 563178 CDS YP_002468037.1 219681651 7262546 314279..315370 1 NC_011833.1 23S rRNA m2A2503 methyltransferase (YfgB) 315370 yfgB 7262546 yfgB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 23S rRNA m2A2503 methyltransferase (YfgB) YP_002468037.1 314279 D 563178 CDS YP_002468038.1 219681652 7262547 315421..316527 1 NC_011833.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 316527 ispG 7262547 ispG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_002468038.1 315421 D 563178 CDS YP_002468039.1 219681653 7262548 316553..317824 1 NC_011833.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 317824 hisS 7262548 hisS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) histidyl-tRNA synthetase YP_002468039.1 316553 D 563178 CDS YP_002468040.1 219681654 7262549 317884..319137 1 NC_011833.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 319137 glyA 7262549 glyA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) serine hydroxymethyltransferase YP_002468040.1 317884 D 563178 CDS YP_002468041.1 219681655 7262550 complement(319225..319899) 1 NC_011833.1 dethiobiotin synthase; dethiobiotin synthetase 319899 bioD 7262550 bioD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dethiobiotin synthetase YP_002468041.1 319225 R 563178 CDS YP_002468042.1 219681656 7262295 complement(320263..321294) 1 NC_011833.1 biotin synthase; biotin synthetase 321294 bioB 7262295 bioB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) biotin synthetase YP_002468042.1 320263 R 563178 CDS YP_002468043.1 219681657 7262553 321373..322659 1 NC_011833.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 322659 bioA 7262553 bioA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_002468043.1 321373 D 563178 CDS YP_002468044.1 219681658 7262554 complement(322668..323672) 1 NC_011833.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 323672 ybhE 7262554 ybhE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 6-phosphogluconolactonase YP_002468044.1 322668 R 563178 CDS YP_002468045.1 219681659 7262555 complement(323796..326234) 1 NC_011833.1 transcription-repair coupling factor 326234 mfd 7262555 mfd Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription-repair coupling factor YP_002468045.1 323796 R 563178 CDS YP_002468046.1 219681660 7262556 326707..327906 1 NC_011833.1 LolCDE ABC lipoprotein transporter (YcfU) 327906 lolC 7262556 lolC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) LolCDE ABC lipoprotein transporter (YcfU) YP_002468046.1 326707 D 563178 CDS YP_002468047.1 219681661 7262557 327899..328585 1 NC_011833.1 LolCDE ABC lipoprotein transporter (YcfV) 328585 lolD 7262557 lolD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) LolCDE ABC lipoprotein transporter (YcfV) YP_002468047.1 327899 D 563178 CDS YP_002468048.1 219681662 7262558 329910..330920 1 NC_011833.1 glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde 3-phosphate dehydrogenase A 330920 gapA 7262558 gapA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glyceraldehyde 3-phosphate dehydrogenase A YP_002468048.1 329910 D 563178 CDS YP_002468049.1 219681663 7262559 complement(331530..332045) 1 NC_011833.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 332045 fldA 7262559 fldA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flavodoxin FldA YP_002468049.1 331530 R 563178 CDS YP_002468050.1 219681664 7262560 332252..333703 1 NC_011833.1 Deoxyribodipyrimidine photo-lyase type I; deoxyribodipyrimidine photolyase 333703 phrB 7262560 phrB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) deoxyribodipyrimidine photolyase YP_002468050.1 332252 D 563178 CDS YP_002468051.1 219681665 7262561 333700..334443 1 NC_011833.1 hypothetical protein 334443 ybgI 7262561 ybgI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468051.1 333700 D 563178 CDS YP_002468052.1 219681666 7262562 334568..337297 1 NC_011833.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 337297 sucA 7262562 sucA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 2-oxoglutarate dehydrogenase E1 component YP_002468052.1 334568 D 563178 CDS YP_002468053.1 219681667 7262563 337313..338575 1 NC_011833.1 2-oxoglutarate dehydrogenase E2 component 338575 sucB 7262563 sucB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 2-oxoglutarate dehydrogenase E2 component YP_002468053.1 337313 D 563178 CDS YP_002468054.1 219681668 7262564 338673..339368 1 NC_011833.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 339368 gpmA 7262564 gpmA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoglyceromutase YP_002468054.1 338673 D 563178 CDS YP_002468055.1 219681669 7262565 339552..340514 1 NC_011833.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 340514 pfkA 7262565 pfkA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 6-phosphofructokinase YP_002468055.1 339552 D 563178 CDS YP_002468056.1 219681670 7262566 340580..341371 1 NC_011833.1 glycerol uptake facilitator protein 341371 glpF 7262566 glpF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glycerol uptake facilitator protein YP_002468056.1 340580 D 563178 CDS YP_002468057.1 219681671 7262567 complement(341380..342147) 1 NC_011833.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 342147 tpiA 7262567 tpiA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) triosephosphate isomerase YP_002468057.1 341380 R 563178 CDS YP_002468058.1 219681672 7262568 complement(342246..342530) 1 NC_011833.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 342530 ihfB 7262568 ihfB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) integration host factor subunit beta YP_002468058.1 342246 R 563178 CDS YP_002468059.1 219681673 7262569 complement(342626..344302) 1 NC_011833.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 344302 rpsA 7262569 rpsA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S1 YP_002468059.1 342626 R 563178 CDS YP_002468060.1 219681674 7262570 complement(345141..346424) 1 NC_011833.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 346424 aroA 7262570 aroA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-phosphoshikimate 1-carboxyvinyltransferase YP_002468060.1 345141 R 563178 CDS YP_002468061.1 219681675 7262571 complement(346492..347577) 1 NC_011833.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 347577 serC 7262571 serC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoserine aminotransferase YP_002468061.1 346492 R 563178 CDS YP_002468062.1 219681676 7262572 complement(347616..348899) 1 NC_011833.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 348899 serS 7262572 serS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) seryl-tRNA synthetase YP_002468062.1 347616 R 563178 CDS YP_002468063.1 219681677 7262573 349248..350207 1 NC_011833.1 thioredoxin reductase 350207 trxB 7262573 trxB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thioredoxin reductase YP_002468063.1 349248 D 563178 CDS YP_002468064.1 219681678 7262574 350314..350532 1 NC_011833.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 350532 infA 7262574 infA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) translation initiation factor IF-1 YP_002468064.1 350314 D 563178 CDS YP_002468065.1 219681679 7262575 350702..352462 1 NC_011833.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 352462 aspS 7262575 aspS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) aspartyl-tRNA synthetase YP_002468065.1 350702 D 563178 CDS YP_002468066.1 219681680 7262576 complement(352473..353261) 1 NC_011833.1 high-affinity zinc uptake system membrane protein ZnuB 353261 znuB 7262576 znuB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) high-affinity zinc uptake system membrane protein ZnuB YP_002468066.1 352473 R 563178 CDS YP_002468067.1 219681681 7262577 complement(353319..354035) 1 NC_011833.1 high-affinity zinc uptake system ATP-binding protein ZnuC 354035 znuC 7262577 znuC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) high-affinity zinc uptake system ATP-binding protein ZnuC YP_002468067.1 353319 R 563178 CDS YP_002468068.1 219681682 7262578 complement(355353..356795) 1 NC_011833.1 pyruvate kinase 356795 pykA 7262578 pykA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) pyruvate kinase YP_002468068.1 355353 R 563178 CDS YP_002468069.1 219681683 7262579 357079..358554 1 NC_011833.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 358554 zwf 7262579 zwf Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glucose-6-phosphate 1-dehydrogenase YP_002468069.1 357079 D 563178 CDS YP_002468070.1 219681684 7262580 358739..359617 1 NC_011833.1 putative metalloprotease; heat shock protein HtpX 359617 htpX 7262580 htpX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) heat shock protein HtpX YP_002468070.1 358739 D 563178 CDS YP_002468071.1 219681685 7262581 359966..360175 1 NC_011833.1 cold-shock DNA-binding protein family; cold shock-like protein CspC 360175 cspC 7262581 cspC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cold shock-like protein CspC YP_002468071.1 359966 D 563178 CDS YP_002468072.1 219681686 7262582 360478..362043 1 NC_011833.1 inner membrane protein (YoaE) 362043 yoaE 7262582 yoaE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) inner membrane protein (YoaE) YP_002468072.1 360478 D 563178 CDS YP_002468073.1 219681687 7262583 362073..362738 1 NC_011833.1 hypothetical protein 362738 yeaZ 7262583 yeaZ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468073.1 362073 D 563178 CDS YP_002468074.1 219681688 7262584 complement(362884..363135) 1 NC_011833.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 363135 minE 7262584 minE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division topological specificity factor MinE YP_002468074.1 362884 R 563178 CDS YP_002468075.1 219681689 7262585 complement(363139..363951) 1 NC_011833.1 septum site-determining protein MinD 363951 minD 7262585 minD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) septum site-determining protein MinD YP_002468075.1 363139 R 563178 CDS YP_002468076.1 219681690 7262586 complement(363978..364691) 1 NC_011833.1 septum site-determining protein MinC; cell division inhibitor MinC 364691 minC 7262586 minC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division inhibitor MinC YP_002468076.1 363978 R 563178 CDS YP_002468077.1 219681691 7262587 365092..365934 1 NC_011833.1 16S rRNA m(2)G 1207 methyltransferase 365934 yjjT 7262587 yjjT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 16S rRNA m(2)G 1207 methyltransferase YP_002468077.1 365092 D 563178 CDS YP_002468078.1 219681692 7262591 complement(366486..367535) 1 NC_011833.1 outer membrane protein A 367535 ompA 7262591 ompA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) outer membrane protein A YP_002468078.1 366486 R 563178 CDS YP_002468079.1 219681693 7262592 complement(367691..369226) 1 NC_011833.1 virulence factor MviN-like protein 369226 mviN 7262592 mviN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) virulence factor MviN-like protein YP_002468079.1 367691 R 563178 CDS YP_002468080.1 219681694 7262593 369500..370552 1 NC_011833.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 370552 pyrC 7262593 pyrC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydroorotase YP_002468080.1 369500 D 563178 CDS YP_002468081.1 219681695 7262594 complement(370572..370979) 1 NC_011833.1 flagella synthesis protein FlgN 370979 flgN 7262594 flgN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagella synthesis protein FlgN YP_002468081.1 370572 R 563178 CDS YP_002468082.1 219681696 7262595 complement(371052..371732) 1 NC_011833.1 flagella basal-body P-ring formation protein FlgA 371732 flgA 7262595 flgA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagella basal-body P-ring formation protein FlgA YP_002468082.1 371052 R 563178 CDS YP_002468083.1 219681697 7262597 372425..372835 1 NC_011833.1 flagellar basal-body rod protein FlgC 372835 flgC 7262597 flgC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar basal-body rod protein FlgC YP_002468083.1 372425 D 563178 CDS YP_002468084.1 219681698 7262598 372847..373557 1 NC_011833.1 basal-body rod modification protein FlgD 373557 flgD 7262598 flgD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) basal-body rod modification protein FlgD YP_002468084.1 372847 D 563178 CDS YP_002468085.1 219681699 7262599 373598..374824 1 NC_011833.1 flagellar hook protein FlgE 374824 flgE 7262599 flgE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar hook protein FlgE YP_002468085.1 373598 D 563178 CDS YP_002468086.1 219681700 7262600 374851..375609 1 NC_011833.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 375609 flgF 7262600 flgF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar basal body rod protein FlgF YP_002468086.1 374851 D 563178 CDS YP_002468087.1 219681701 7262601 375627..376409 1 NC_011833.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 376409 flgG 7262601 flgG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar basal body rod protein FlgG YP_002468087.1 375627 D 563178 CDS YP_002468088.1 219681702 7262602 376493..377209 1 NC_011833.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 377209 flgH 7262602 flgH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar basal body L-ring protein YP_002468088.1 376493 D 563178 CDS YP_002468089.1 219681703 7262603 377390..378547 1 NC_011833.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring protein 378547 flgI 7262603 flgI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar basal body P-ring protein YP_002468089.1 377390 D 563178 CDS YP_002468090.1 219681704 7262604 378547..378846 1 NC_011833.1 flagellar protein FlgJ 378846 flgJ 7262604 flgJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar protein FlgJ YP_002468090.1 378547 D 563178 CDS YP_002468091.1 219681705 7262605 378947..380578 1 NC_011833.1 flagellar hook-associated protein 1 380578 flgK 7262605 flgK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) flagellar hook-associated protein 1 YP_002468091.1 378947 D 563178 CDS YP_002468092.1 219681706 7262606 complement(380743..383451) 1 NC_011833.1 RNAse E; ribonuclease E 383451 rne 7262606 rne Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribonuclease E YP_002468092.1 380743 R 563178 CDS YP_002468093.1 219681707 7262607 383786..384730 1 NC_011833.1 ribosomal large subunit pseudouridine synthase C; ribosomal large subunit pseudouridine synthase C 384730 rluC 7262607 rluC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribosomal large subunit pseudouridine synthase C YP_002468093.1 383786 D 563178 CDS YP_002468094.1 219681708 7262608 384776..384940 1 NC_011833.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 384940 rpmF 7262608 rpmF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L32 YP_002468094.1 384776 D 563178 CDS YP_002468095.1 219681709 7262609 386307..387041 1 NC_011833.1 3-oxoacyl-[acyl-carrier-protein] reductase; 3-oxoacyl-ACP reductase 387041 fabG 7262609 fabG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-oxoacyl-ACP reductase YP_002468095.1 386307 D 563178 CDS YP_002468096.1 219681710 7262610 387118..387360 1 NC_011833.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 387360 acpP 7262610 acpP Buchnera aphidicola str. 5A (Acyrthosiphon pisum) acyl carrier protein YP_002468096.1 387118 D 563178 CDS YP_002468097.1 219681711 7262611 387431..388069 1 NC_011833.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 388069 tmk 7262611 tmk Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thymidylate kinase YP_002468097.1 387431 D 563178 CDS YP_002468098.1 219681712 7262612 388066..389046 1 NC_011833.1 DNA polymerase III, delta prime subunit; DNA polymerase III subunit delta' 389046 holB 7262612 holB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III subunit delta' YP_002468098.1 388066 D 563178 CDS YP_002468099.1 219681713 7262613 389080..389874 1 NC_011833.1 metallodependent hydrolase (YcfH) 389874 ycfH 7262613 ycfH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) metallodependent hydrolase (YcfH) YP_002468099.1 389080 D 563178 CDS YP_002468100.1 219681714 7262614 389970..391403 1 NC_011833.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 391403 ptsG 7262614 ptsG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) PTS system glucose-specific transporter subunit IIBC YP_002468100.1 389970 D 563178 CDS YP_002468101.1 219681715 7262615 391423..391767 1 NC_011833.1 purine nucleoside phosphoramidase (YcfF) 391767 hinT 7262615 hinT Buchnera aphidicola str. 5A (Acyrthosiphon pisum) purine nucleoside phosphoramidase (YcfF) YP_002468101.1 391423 D 563178 CDS YP_002468102.1 219681716 7262616 391844..392353 1 NC_011833.1 outer membrane lipoprotein (YcfM) 392353 ycfM 7262616 ycfM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) outer membrane lipoprotein (YcfM) YP_002468102.1 391844 D 563178 CDS YP_002468103.1 219681717 7262617 complement(392602..393750) 1 NC_011833.1 OmpF-like porin 393750 ompF 7262617 ompF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) OmpF-like porin YP_002468103.1 392602 R 563178 CDS YP_002468104.1 219681718 7262618 complement(393890..395290) 1 NC_011833.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 395290 asnC 7262618 asnC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) asparaginyl-tRNA synthetase YP_002468104.1 393890 R 563178 CDS YP_002468105.1 219681719 7262619 complement(395438..396637) 1 NC_011833.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 396637 pncB 7262619 pncB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) nicotinate phosphoribosyltransferase YP_002468105.1 395438 R 563178 CDS YP_002468106.1 219681720 7262620 397059..397922 1 NC_011833.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 397922 pyrD 7262620 pyrD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydroorotate dehydrogenase 2 YP_002468106.1 397059 D 563178 CDS YP_002468107.1 219681721 7262621 398098..400203 1 NC_011833.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 400203 rlmL 7262621 rlmL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 23S rRNA m(2)G2445 methyltransferase YP_002468107.1 398098 D 563178 CDS YP_002468108.1 219681722 7262622 400223..402013 1 NC_011833.1 ABC transporter ATP-binding protein 402013 uup 7262622 uup Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ABC transporter ATP-binding protein YP_002468108.1 400223 D 563178 CDS YP_002468109.1 219681723 7262623 complement(402017..402991) 1 NC_011833.1 hypothetical protein 402991 yceA 7262623 yceA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468109.1 402017 R 563178 CDS YP_002468110.1 219681724 7262624 complement(403048..405915) 1 NC_011833.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 405915 valS 7262624 valS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) valyl-tRNA synthetase YP_002468110.1 403048 R 563178 CDS YP_002468111.1 219681725 7262625 complement(405992..407491) 1 NC_011833.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 407491 pepA 7262625 pepA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) leucyl aminopeptidase YP_002468111.1 405992 R 563178 CDS YP_002468112.1 219681726 7262626 407751..408767 1 NC_011833.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 408767 argF 7262626 argF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ornithine carbamoyltransferase subunit I YP_002468112.1 407751 D 563178 CDS YP_002468113.1 219681727 7262627 408886..409818 1 NC_011833.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 409818 pyrB 7262627 pyrB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) aspartate carbamoyltransferase catalytic subunit YP_002468113.1 408886 D 563178 CDS YP_002468114.1 219681728 7262628 409826..410290 1 NC_011833.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase regulatory subunit 410290 pyrI 7262628 pyrI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) aspartate carbamoyltransferase regulatory subunit YP_002468114.1 409826 D 563178 CDS YP_002468115.1 219681729 7262629 410336..410722 1 NC_011833.1 L-PSP (mRNA) endoribonuclease (YhaR) 410722 tdcF 7262629 tdcF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) L-PSP (mRNA) endoribonuclease (YhaR) YP_002468115.1 410336 D 563178 CDS YP_002468116.1 219681730 7262630 complement(410809..412614) 1 NC_011833.1 ATP-dependent RNA helicase DeaD 412614 deaD 7262630 deaD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent RNA helicase DeaD YP_002468116.1 410809 R 563178 CDS YP_002468117.1 219681731 7262631 complement(412995..415118) 1 NC_011833.1 polynucleotide phosphorylase/polyadenylase 415118 pnp 7262631 pnp Buchnera aphidicola str. 5A (Acyrthosiphon pisum) polynucleotide phosphorylase/polyadenylase YP_002468117.1 412995 R 563178 CDS YP_002468118.1 219681732 7262632 complement(415320..415589) 1 NC_011833.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 415589 rpsO 7262632 rpsO Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S15 YP_002468118.1 415320 R 563178 CDS YP_002468119.1 219681733 7262633 complement(415694..416632) 1 NC_011833.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 416632 truB 7262633 truB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA pseudouridine synthase B YP_002468119.1 415694 R 563178 CDS YP_002468120.1 219681734 7262551 complement(416670..417032) 1 NC_011833.1 ribosome-binding factor A 417032 rbfA 7262551 rbfA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribosome-binding factor A YP_002468120.1 416670 R 563178 CDS YP_002468121.1 219681735 7262388 complement(417078..419672) 1 NC_011833.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 419672 infB 7262388 infB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) translation initiation factor IF-2 YP_002468121.1 417078 R 563178 CDS YP_002468122.1 219681736 7262389 complement(419690..421180) 1 NC_011833.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 421180 nusA 7262389 nusA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription elongation factor NusA YP_002468122.1 419690 R 563178 CDS YP_002468123.1 219681737 7262391 complement(421653..421982) 1 NC_011833.1 protein translocase subunit secG; preprotein translocase subunit SecG 421982 secG 7262391 secG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) preprotein translocase subunit SecG YP_002468123.1 421653 R 563178 CDS YP_002468124.1 219681738 7262392 complement(422245..423579) 1 NC_011833.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 423579 glmM 7262392 glmM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoglucosamine mutase YP_002468124.1 422245 R 563178 CDS YP_002468125.1 219681739 7262393 complement(423799..425634) 1 NC_011833.1 membrane protease FtsH catalytic subunit; cell division protein FtsH 425634 hflB 7262393 hflB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cell division protein FtsH YP_002468125.1 423799 R 563178 CDS YP_002468126.1 219681740 7262395 complement(426393..426872) 1 NC_011833.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 426872 greA 7262395 greA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription elongation factor GreA YP_002468126.1 426393 R 563178 CDS YP_002468127.1 219681741 7262396 427396..427638 1 NC_011833.1 hypothetical protein 427638 yrbA 7262396 yrbA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468127.1 427396 D 563178 CDS YP_002468128.1 219681742 7262397 427700..428950 1 NC_011833.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 428950 murA 7262397 murA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_002468128.1 427700 D 563178 CDS YP_002468129.1 219681743 7262398 429089..429415 1 NC_011833.1 LSU ribosomal protein L21P; 50S ribosomal protein L21 429415 rplU 7262398 rplU Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L21 YP_002468129.1 429089 D 563178 CDS YP_002468130.1 219681744 7262399 429420..429674 1 NC_011833.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 429674 rpmA 7262399 rpmA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L27 YP_002468130.1 429420 D 563178 CDS YP_002468131.1 219681745 7262400 429826..430830 1 NC_011833.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 430830 obgE 7262400 obgE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTPase ObgE YP_002468131.1 429826 D 563178 CDS YP_002468132.1 219681746 7262401 complement(430898..431290) 1 NC_011833.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 431290 rpsI 7262401 rpsI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S9 YP_002468132.1 430898 R 563178 CDS YP_002468133.1 219681747 7262402 complement(431311..431739) 1 NC_011833.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 431739 rplM 7262402 rplM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L13 YP_002468133.1 431311 R 563178 CDS YP_002468134.1 219681748 7262403 431991..433148 1 NC_011833.1 chorismate mutase 433148 pheA 7262403 pheA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chorismate mutase YP_002468134.1 431991 D 563178 CDS YP_002468135.1 219681749 7262404 433330..434685 1 NC_011833.1 signal recognition particle subunit FFH/SRP54 (srp54); signal recognition particle protein 434685 ffh 7262404 ffh Buchnera aphidicola str. 5A (Acyrthosiphon pisum) signal recognition particle protein YP_002468135.1 433330 D 563178 CDS YP_002468136.1 219681750 7262405 434794..435033 1 NC_011833.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 435033 rpsP 7262405 rpsP Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S16 YP_002468136.1 434794 D 563178 CDS YP_002468137.1 219681751 7262406 435035..435565 1 NC_011833.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 435565 rimM 7262406 rimM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 16S rRNA-processing protein RimM YP_002468137.1 435035 D 563178 CDS YP_002468138.1 219681752 7262407 435580..436293 1 NC_011833.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 436293 trmD 7262407 trmD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA (guanine-N(1)-)-methyltransferase YP_002468138.1 435580 D 563178 CDS YP_002468139.1 219681753 7262408 436392..436739 1 NC_011833.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 436739 rplS 7262408 rplS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L19 YP_002468139.1 436392 D 563178 CDS YP_002468140.1 219681754 7262409 complement(436823..438274) 1 NC_011833.1 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62; TldD protein 438274 tldD 7262409 tldD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) TldD protein YP_002468140.1 436823 R 563178 CDS YP_002468141.1 219681755 7262410 438432..438884 1 NC_011833.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 438884 aroD 7262410 aroD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-dehydroquinate dehydratase YP_002468141.1 438432 D 563178 CDS YP_002468142.1 219681756 7262411 complement(439076..439372) 1 NC_011833.1 DNA-binding protein Fis; factor-for-inversion stimulation protein 439372 fis 7262411 fis Buchnera aphidicola str. 5A (Acyrthosiphon pisum) factor-for-inversion stimulation protein YP_002468142.1 439076 R 563178 CDS YP_002468143.1 219681757 7262412 complement(439541..440479) 1 NC_011833.1 ribosomal large subunit pseudouridine synthase D; ribosomal large subunit pseudouridine synthase D 440479 rluD 7262412 rluD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribosomal large subunit pseudouridine synthase D YP_002468143.1 439541 R 563178 CDS YP_002468144.1 219681758 7262413 440644..441384 1 NC_011833.1 hypothetical 27.8 kDa lipoprotein 441384 yfiO 7262413 yfiO Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical 27.8 kDa lipoprotein YP_002468144.1 440644 D 563178 CDS YP_002468145.1 219681759 7262414 441550..444186 1 NC_011833.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 444186 alaS 7262414 alaS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) alanyl-tRNA synthetase YP_002468145.1 441550 D 563178 CDS YP_002468146.1 219681760 7262415 444381..444554 1 NC_011833.1 carbon storage regulator 444554 csrA 7262415 csrA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) carbon storage regulator YP_002468146.1 444381 D 563178 CDS YP_002468147.1 219681761 7262418 445012..446568 1 NC_011833.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 446568 gshA 7262418 gshA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutamate--cysteine ligase YP_002468147.1 445012 D 563178 CDS YP_002468148.1 219681762 7262419 complement(446715..447851) 1 NC_011833.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 447851 metK 7262419 metK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) S-adenosylmethionine synthetase YP_002468148.1 446715 R 563178 CDS YP_002468149.1 219681763 7262420 448086..448838 1 NC_011833.1 endonuclease I 448838 endA 7262420 endA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) endonuclease I YP_002468149.1 448086 D 563178 CDS YP_002468150.1 219681764 7262421 448810..449571 1 NC_011833.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 449571 rsmE 7262421 rsmE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 16S ribosomal RNA methyltransferase RsmE YP_002468150.1 448810 D 563178 CDS YP_002468151.1 219681765 7262422 complement(449645..450316) 1 NC_011833.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 450316 rpiA 7262422 rpiA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribose-5-phosphate isomerase A YP_002468151.1 449645 R 563178 CDS YP_002468152.1 219681766 7262426 450943..452658 1 NC_011833.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 452658 glnS 7262426 glnS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutaminyl-tRNA synthetase YP_002468152.1 450943 D 563178 CDS YP_002468153.1 219681767 7262427 452832..454469 1 NC_011833.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 454469 pyrG 7262427 pyrG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) CTP synthetase YP_002468153.1 452832 D 563178 CDS YP_002468154.1 219681768 7262428 454499..455803 1 NC_011833.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 455803 eno 7262428 eno Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphopyruvate hydratase YP_002468154.1 454499 D 563178 CDS YP_002468155.1 219681769 7262429 complement(455959..456963) 1 NC_011833.1 lipoprotein NlpD 456963 nlpD 7262429 nlpD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lipoprotein NlpD YP_002468155.1 455959 R 563178 CDS YP_002468156.1 219681770 7262430 complement(457053..457538) 1 NC_011833.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 457538 ispF 7262430 ispF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_002468156.1 457053 R 563178 CDS YP_002468157.1 219681771 7262431 complement(457554..458267) 1 NC_011833.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 458267 ispD 7262431 ispD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_002468157.1 457554 R 563178 CDS YP_002468158.1 219681772 7262432 complement(458350..458565) 1 NC_011833.1 cell division protein FtsB (YgbQ); essential cell division protein FtsB (YgbQ) 458565 ftsB 7262432 ftsB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) essential cell division protein FtsB (YgbQ) YP_002468158.1 458350 R 563178 CDS YP_002468159.1 219681773 7262433 complement(458623..459243) 1 NC_011833.1 adenylylsulfate kinase 459243 cysC 7262433 cysC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) adenylylsulfate kinase YP_002468159.1 458623 R 563178 CDS YP_002468160.1 219681774 7262434 complement(459244..460665) 1 NC_011833.1 sulfate adenylyltransferase subunit 1; sulfate adenylyltransferase 460665 cysN 7262434 cysN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfate adenylyltransferase YP_002468160.1 459244 R 563178 CDS YP_002468161.1 219681775 7262435 complement(460684..461592) 1 NC_011833.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 461592 cysD 7262435 cysD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfate adenylyltransferase subunit 2 YP_002468161.1 460684 R 563178 CDS YP_002468162.1 219681776 7262436 complement(461602..463023) 1 NC_011833.1 uroporphyrinogen-III C-methyltransferase; ferrochelatase 463023 cysG 7262436 cysG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ferrochelatase YP_002468162.1 461602 R 563178 CDS YP_002468163.1 219681777 7262437 complement(463362..464096) 1 NC_011833.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 464096 cysH 7262437 cysH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoadenosine phosphosulfate reductase YP_002468163.1 463362 R 563178 CDS YP_002468164.1 219681778 7262438 complement(464112..465821) 1 NC_011833.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 465821 cysI 7262438 cysI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfite reductase subunit beta YP_002468164.1 464112 R 563178 CDS YP_002468165.1 219681779 7262439 complement(465821..467626) 1 NC_011833.1 sulfite reductase (NADPH) alpha subunit; sulfite reductase (NADPH) flavoprotein alpha-component 467626 cysJ 7262439 cysJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfite reductase (NADPH) flavoprotein alpha-component YP_002468165.1 465821 R 563178 CDS YP_002468166.1 219681780 7262440 complement(467817..470225) 1 NC_011833.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 470225 mutS 7262440 mutS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA mismatch repair protein MutS YP_002468166.1 467817 R 563178 CDS YP_002468167.1 219681781 7262441 470382..471020 1 NC_011833.1 thiol:disulfide interchange protein DsbA precursor 471020 dsbA 7262441 dsbA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thiol:disulfide interchange protein DsbA precursor YP_002468167.1 470382 D 563178 CDS YP_002468168.1 219681782 7262442 471141..472001 1 NC_011833.1 DNA polymerase I 472001 polA 7262442 polA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase I YP_002468168.1 471141 D 563178 CDS YP_002468169.1 219681783 7262443 complement(472064..472681) 1 NC_011833.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 472681 engB 7262443 engB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribosome biogenesis GTP-binding protein YsxC YP_002468169.1 472064 R 563178 CDS YP_002468170.1 219681784 7262444 472932..474755 1 NC_011833.1 GTP-binding protein BipA 474755 typA 7262444 typA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP-binding protein BipA YP_002468170.1 472932 D 563178 CDS YP_002468171.1 219681785 7262445 complement(474878..475501) 1 NC_011833.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 475501 gmk 7262445 gmk Buchnera aphidicola str. 5A (Acyrthosiphon pisum) guanylate kinase YP_002468171.1 474878 R 563178 CDS YP_002468172.1 219681786 7262446 complement(475601..476560) 1 NC_011833.1 folate-binding protein (YgfZ) 476560 ygfZ 7262446 ygfZ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) folate-binding protein (YgfZ) YP_002468172.1 475601 R 563178 CDS YP_002468173.1 219681787 7262447 476779..477828 1 NC_011833.1 bacterial peptide chain release factor 2 (bRF-2); peptide chain release factor 2 477828 prfB 7262447 prfB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptide chain release factor 2 YP_002468173.1 476779 D 563178 CDS YP_002468174.1 219681788 7262448 477838..479358 1 NC_011833.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 479358 lysS 7262448 lysS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lysyl-tRNA synthetase YP_002468174.1 477838 D 563178 CDS YP_002468175.1 219681789 7262449 479424..480671 1 NC_011833.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 480671 lysA 7262449 lysA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) diaminopimelate decarboxylase YP_002468175.1 479424 D 563178 CDS YP_002468176.1 219681790 7262450 480737..481582 1 NC_011833.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 481582 lgt 7262450 lgt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) prolipoprotein diacylglyceryl transferase YP_002468176.1 480737 D 563178 CDS YP_002468177.1 219681791 7262451 481596..482390 1 NC_011833.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 482390 thyA 7262451 thyA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thymidylate synthase YP_002468177.1 481596 D 563178 CDS YP_002468178.1 219681792 7262452 482458..483777 1 NC_011833.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 483777 miaB 7262452 miaB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) (dimethylallyl)adenosine tRNA methylthiotransferase YP_002468178.1 482458 D 563178 CDS YP_002468179.1 219681793 7262453 483931..484266 1 NC_011833.1 hypothetical protein 484266 ybeY 7262453 ybeY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468179.1 483931 D 563178 CDS YP_002468180.1 219681794 7262454 484347..485222 1 NC_011833.1 hypothetical protein 485222 ybeX 7262454 ybeX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468180.1 484347 D 563178 CDS YP_002468181.1 219681795 7262455 485326..487905 1 NC_011833.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 487905 leuS 7262455 leuS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) leucyl-tRNA synthetase YP_002468181.1 485326 D 563178 CDS YP_002468182.1 219681796 7262456 487945..488940 1 NC_011833.1 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 488940 holA 7262456 holA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III subunit delta YP_002468182.1 487945 D 563178 CDS YP_002468183.1 219681797 7262457 488963..489607 1 NC_011833.1 nicotinate-nucleotide adenylyltransferase; nicotinate-mononucleotide adenylyltransferase (YbeN) 489607 nadD 7262457 nadD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) nicotinate-mononucleotide adenylyltransferase (YbeN) YP_002468183.1 488963 D 563178 CDS YP_002468184.1 219681798 7262458 489668..489898 1 NC_011833.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 489898 sirA 7262458 sirA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfur transfer protein SirA YP_002468184.1 489668 D 563178 CDS YP_002468185.1 219681799 7262459 complement(490045..491160) 1 NC_011833.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 491160 asd 7262459 asd Buchnera aphidicola str. 5A (Acyrthosiphon pisum) aspartate-semialdehyde dehydrogenase YP_002468185.1 490045 R 563178 CDS YP_002468186.1 219681800 7262460 491456..492046 1 NC_011833.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 492046 yhgN 7262460 yhgN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) putative dITP- and XTP- hydrolase YP_002468186.1 491456 D 563178 CDS YP_002468187.1 219681801 7262461 492159..493331 1 NC_011833.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 493331 pgk 7262461 pgk Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphoglycerate kinase YP_002468187.1 492159 D 563178 CDS YP_002468188.1 219681802 7262462 493347..494423 1 NC_011833.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 494423 fba 7262462 fba Buchnera aphidicola str. 5A (Acyrthosiphon pisum) fructose-bisphosphate aldolase YP_002468188.1 493347 D 563178 CDS YP_002468189.1 219681803 7262463 494559..495404 1 NC_011833.1 mechanosensitive channel MscS 495404 yggB 7262463 yggB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) mechanosensitive channel MscS YP_002468189.1 494559 D 563178 CDS YP_002468190.1 219681804 7262464 495463..498687 1 NC_011833.1 DNA helicase/exodeoxyribonuclease V, gamma subunit; exodeoxyribonuclease V 125 kDa polypeptide 498687 recC 7262464 recC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) exodeoxyribonuclease V 125 kDa polypeptide YP_002468190.1 495463 D 563178 CDS YP_002468191.1 219681805 7262465 498692..502216 1 NC_011833.1 DNA helicase/exodeoxyribonuclease V, beta subunit; exodeoxyribonuclease V 135 kDa polypeptide 502216 recB 7262465 recB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) exodeoxyribonuclease V 135 kDa polypeptide YP_002468191.1 498692 D 563178 CDS YP_002468192.1 219681806 7262466 502222..504030 1 NC_011833.1 DNA helicase/exodeoxyribonuclease V, alpha subunit; exodeoxyribonuclease V 67 kDa polypeptide 504030 recD 7262466 recD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) exodeoxyribonuclease V 67 kDa polypeptide YP_002468192.1 502222 D 563178 CDS YP_002468193.1 219681807 7262467 complement(504069..505397) 1 NC_011833.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 505397 argA 7262467 argA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) N-acetylglutamate synthase YP_002468193.1 504069 R 563178 CDS YP_002468194.1 219681808 7262386 505764..506843 1 NC_011833.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 506843 mltA 7262386 mltA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) murein transglycosylase A YP_002468194.1 505764 D 563178 CDS YP_002468195.1 219681809 7262214 506882..507364 1 NC_011833.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 507364 ribH 7262214 ribH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 6,7-dimethyl-8-ribityllumazine synthase YP_002468195.1 506882 D 563178 CDS YP_002468196.1 219681810 7262215 507394..508365 1 NC_011833.1 thiamin-monophosphate kinase 508365 thiL 7262215 thiL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thiamin-monophosphate kinase YP_002468196.1 507394 D 563178 CDS YP_002468197.1 219681811 7262216 508421..508846 1 NC_011833.1 diaminohydroxyphosphoribosylaminopyrimidine deaminase; riboflavin deaminase 508846 ribD1 7262216 ribD1 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) riboflavin deaminase YP_002468197.1 508421 D 563178 CDS YP_002468198.1 219681812 7262217 508889..509512 1 NC_011833.1 5-amino-6-(5-phosphoribosylamino)uracil reductase; riboflavin reductase 509512 ribD2 7262217 ribD2 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) riboflavin reductase YP_002468198.1 508889 D 563178 CDS YP_002468199.1 219681813 7262218 509549..509980 1 NC_011833.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 509980 nusB 7262218 nusB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription antitermination protein NusB YP_002468199.1 509549 D 563178 CDS YP_002468200.1 219681814 7262219 complement(510035..511861) 1 NC_011833.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 511861 dxs 7262219 dxs Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 1-deoxy-D-xylulose-5-phosphate synthase YP_002468200.1 510035 R 563178 CDS YP_002468201.1 219681815 7262220 complement(511919..512767) 1 NC_011833.1 farnesyl-diphosphate synthase; geranyltranstransferase 512767 ispA 7262220 ispA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) geranyltranstransferase YP_002468201.1 511919 R 563178 CDS YP_002468202.1 219681816 7262221 complement(512819..513991) 1 NC_011833.1 hypothetical protein 513991 yajR 7262221 yajR Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468202.1 512819 R 563178 CDS YP_002468203.1 219681817 7262222 514065..514409 1 NC_011833.1 hypothetical protein 514409 yccK 7262222 yccK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468203.1 514065 D 563178 CDS YP_002468204.1 219681818 7262223 complement(514430..515287) 1 NC_011833.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 515287 cyoE 7262223 cyoE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) protoheme IX farnesyltransferase YP_002468204.1 514430 R 563178 CDS YP_002468205.1 219681819 7262224 complement(515315..515632) 1 NC_011833.1 cytochrome O ubiquinol oxidase subunit IV 515632 cyoD 7262224 cyoD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit IV YP_002468205.1 515315 R 563178 CDS YP_002468206.1 219681820 7262225 complement(515632..516249) 1 NC_011833.1 cytochrome O ubiquinol oxidase subunit III 516249 cyoC 7262225 cyoC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit III YP_002468206.1 515632 R 563178 CDS YP_002468207.1 219681821 7262226 complement(516246..518234) 1 NC_011833.1 cytochrome O ubiquinol oxidase subunit I 518234 cyoB 7262226 cyoB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit I YP_002468207.1 516246 R 563178 CDS YP_002468208.1 219681822 7262227 complement(518239..519129) 1 NC_011833.1 cytochrome O ubiquinol oxidase subunit II 519129 cyoA 7262227 cyoA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit II YP_002468208.1 518239 R 563178 CDS YP_002468209.1 219681823 7262228 519428..519742 1 NC_011833.1 transcriptional regulator BolA; BolA protein 519742 bolA 7262228 bolA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) BolA protein YP_002468209.1 519428 D 563178 CDS YP_002468210.1 219681824 7262229 519877..521205 1 NC_011833.1 trigger factor 521205 tig 7262229 tig Buchnera aphidicola str. 5A (Acyrthosiphon pisum) trigger factor YP_002468210.1 519877 D 563178 CDS YP_002468211.1 219681825 7262230 521340..521966 1 NC_011833.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 521966 clpP 7262230 clpP Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent Clp protease proteolytic subunit YP_002468211.1 521340 D 563178 CDS YP_002468212.1 219681826 7262231 522065..523354 1 NC_011833.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 523354 clpX 7262231 clpX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent protease ATP-binding subunit ClpX YP_002468212.1 522065 D 563178 CDS YP_002468213.1 219681827 7262232 523546..525879 1 NC_011833.1 Lon-A peptidase. Serine peptidase. MEROPS family S16; ATP-dependent protease LA 525879 lon 7262232 lon Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent protease LA YP_002468213.1 523546 D 563178 CDS YP_002468214.1 219681828 7262233 526021..527892 1 NC_011833.1 peptidyl-prolyl cis-trans isomerase D 527892 ppiD 7262233 ppiD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptidyl-prolyl cis-trans isomerase D YP_002468214.1 526021 D 563178 CDS YP_002468215.1 219681829 7262234 528859..530628 1 NC_011833.1 multidrug resistance-like ATP-binding protein Mdl 530628 mdl 7262234 mdl Buchnera aphidicola str. 5A (Acyrthosiphon pisum) multidrug resistance-like ATP-binding protein Mdl YP_002468215.1 528859 D 563178 CDS YP_002468216.1 219681830 7262235 530600..532372 1 NC_011833.1 multidrug resistance-like ATP-binding protein MdlB 532372 mdlB 7262235 mdlB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) multidrug resistance-like ATP-binding protein MdlB YP_002468216.1 530600 D 563178 CDS YP_002468217.1 219681831 7262236 532667..533752 1 NC_011833.1 DNA polymerase III, gamma subunit; DNA polymerase III subunits gamma and tau 533752 dnaX 7262236 dnaX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA polymerase III subunits gamma and tau YP_002468217.1 532667 D 563178 CDS YP_002468218.1 219681832 7262237 534072..534401 1 NC_011833.1 hypothetical protein 534401 ybaB 7262237 ybaB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468218.1 534072 D 563178 CDS YP_002468219.1 219681833 7262238 534547..536421 1 NC_011833.1 molecular chaperone; heat shock protein 90 536421 htpG 7262238 htpG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) heat shock protein 90 YP_002468219.1 534547 D 563178 CDS YP_002468220.1 219681834 7262239 536494..537141 1 NC_011833.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 537141 adk 7262239 adk Buchnera aphidicola str. 5A (Acyrthosiphon pisum) adenylate kinase YP_002468220.1 536494 D 563178 CDS YP_002468221.1 219681835 7262241 537372..538229 1 NC_011833.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 538229 folD 7262241 folD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase YP_002468221.1 537372 D 563178 CDS YP_002468222.1 219681836 7262242 complement(538226..539620) 1 NC_011833.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 539620 cysS 7262242 cysS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cysteinyl-tRNA synthetase YP_002468222.1 538226 R 563178 CDS YP_002468223.1 219681837 7262243 539881..540144 1 NC_011833.1 hypothetical protein 540144 ybeD 7262243 ybeD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468223.1 539881 D 563178 CDS YP_002468224.1 219681838 7262244 complement(540251..540460) 1 NC_011833.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 540460 cspE 7262244 cspE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cold shock protein CspE YP_002468224.1 540251 R 563178 CDS YP_002468225.1 219681839 7262248 complement(544274..545095) 1 NC_011833.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 545095 aroE 7262248 aroE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) shikimate 5-dehydrogenase YP_002468225.1 544274 R 563178 CDS YP_002468226.1 219681840 7262249 complement(545088..545615) 1 NC_011833.1 dsRNA-binding protein, putative ribosome maturation factor (YrdC) 545615 rimN 7262249 rimN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dsRNA-binding protein, putative ribosome maturation factor (YrdC) YP_002468226.1 545088 R 563178 CDS YP_002468227.1 219681841 7262250 complement(545713..546186) 1 NC_011833.1 Smg protein 546186 smg 7262250 smg Buchnera aphidicola str. 5A (Acyrthosiphon pisum) Smg protein YP_002468227.1 545713 R 563178 CDS YP_002468228.1 219681842 7262251 546430..546951 1 NC_011833.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 546951 def 7262251 def Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptide deformylase YP_002468228.1 546430 D 563178 CDS YP_002468229.1 219681843 7262252 546959..547903 1 NC_011833.1 methionyl-tRNA formyltransferase 547903 fmt 7262252 fmt Buchnera aphidicola str. 5A (Acyrthosiphon pisum) methionyl-tRNA formyltransferase YP_002468229.1 546959 D 563178 CDS YP_002468230.1 219681844 7262253 complement(548031..548423) 1 NC_011833.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 548423 rplQ 7262253 rplQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L17 YP_002468230.1 548031 R 563178 CDS YP_002468231.1 219681845 7262254 complement(548468..549457) 1 NC_011833.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 549457 rpoA 7262254 rpoA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit alpha YP_002468231.1 548468 R 563178 CDS YP_002468232.1 219681846 7262255 complement(549486..550106) 1 NC_011833.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 550106 rpsD 7262255 rpsD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S4 YP_002468232.1 549486 R 563178 CDS YP_002468233.1 219681847 7262256 complement(550132..550527) 1 NC_011833.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 550527 rpsK 7262256 rpsK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S11 YP_002468233.1 550132 R 563178 CDS YP_002468234.1 219681848 7262257 complement(550545..550901) 1 NC_011833.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 550901 rpsM 7262257 rpsM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S13 YP_002468234.1 550545 R 563178 CDS YP_002468235.1 219681849 7262258 complement(550995..551111) 1 NC_011833.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 551111 rpmJ 7262258 rpmJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L36 YP_002468235.1 550995 R 563178 CDS YP_002468236.1 219681850 7262259 complement(551137..552450) 1 NC_011833.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 552450 secY 7262259 secY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) preprotein translocase subunit SecY YP_002468236.1 551137 R 563178 CDS YP_002468237.1 219681851 7262260 complement(552461..552895) 1 NC_011833.1 late assembly protein; 50S ribosomal protein L15 552895 rplO 7262260 rplO Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L15 YP_002468237.1 552461 R 563178 CDS YP_002468238.1 219681852 7262261 complement(552900..553079) 1 NC_011833.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 553079 rpmD 7262261 rpmD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L30 YP_002468238.1 552900 R 563178 CDS YP_002468239.1 219681853 7262262 complement(553089..553592) 1 NC_011833.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 553592 rpsE 7262262 rpsE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S5 YP_002468239.1 553089 R 563178 CDS YP_002468240.1 219681854 7262263 complement(553608..553976) 1 NC_011833.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 553976 rplR 7262263 rplR Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L18 YP_002468240.1 553608 R 563178 CDS YP_002468241.1 219681855 7262264 complement(553978..554535) 1 NC_011833.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 554535 rplF 7262264 rplF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L6 YP_002468241.1 553978 R 563178 CDS YP_002468242.1 219681856 7262265 complement(554525..554917) 1 NC_011833.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 554917 rpsH 7262265 rpsH Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S8 YP_002468242.1 554525 R 563178 CDS YP_002468243.1 219681857 7262266 complement(554946..555251) 1 NC_011833.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 555251 rpsN 7262266 rpsN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S14 YP_002468243.1 554946 R 563178 CDS YP_002468244.1 219681858 7262267 complement(555269..555808) 1 NC_011833.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 555808 rplE 7262267 rplE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L5 YP_002468244.1 555269 R 563178 CDS YP_002468245.1 219681859 7262268 complement(555823..556137) 1 NC_011833.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 556137 rplX 7262268 rplX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L24 YP_002468245.1 555823 R 563178 CDS YP_002468246.1 219681860 7262269 complement(556163..556531) 1 NC_011833.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 556531 rplN 7262269 rplN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L14 YP_002468246.1 556163 R 563178 CDS YP_002468247.1 219681861 7262270 complement(556645..556896) 1 NC_011833.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 556896 rpsQ 7262270 rpsQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S17 YP_002468247.1 556645 R 563178 CDS YP_002468248.1 219681862 7262271 complement(556896..557093) 1 NC_011833.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 557093 rpmC 7262271 rpmC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L29 YP_002468248.1 556896 R 563178 CDS YP_002468249.1 219681863 7262272 complement(557093..557503) 1 NC_011833.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 557503 rplP 7262272 rplP Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L16 YP_002468249.1 557093 R 563178 CDS YP_002468250.1 219681864 7262273 complement(557524..558225) 1 NC_011833.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 558225 rpsC 7262273 rpsC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S3 YP_002468250.1 557524 R 563178 CDS YP_002468251.1 219681865 7262274 complement(558244..558576) 1 NC_011833.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 558576 rplV 7262274 rplV Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L22 YP_002468251.1 558244 R 563178 CDS YP_002468252.1 219681866 7262275 complement(558612..558890) 1 NC_011833.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 558890 rpsS 7262275 rpsS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S19 YP_002468252.1 558612 R 563178 CDS YP_002468253.1 219681867 7262276 complement(558910..559731) 1 NC_011833.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 559731 rplB 7262276 rplB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L2 YP_002468253.1 558910 R 563178 CDS YP_002468254.1 219681868 7262277 complement(559746..560048) 1 NC_011833.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 560048 rplW 7262277 rplW Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L23 YP_002468254.1 559746 R 563178 CDS YP_002468255.1 219681869 7262278 complement(560045..560650) 1 NC_011833.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 560650 rplD 7262278 rplD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L4 YP_002468255.1 560045 R 563178 CDS YP_002468256.1 219681870 7262279 complement(560668..561297) 1 NC_011833.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 561297 rplC 7262279 rplC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L3 YP_002468256.1 560668 R 563178 CDS YP_002468257.1 219681871 7262280 complement(561328..561639) 1 NC_011833.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 561639 rpsJ 7262280 rpsJ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S10 YP_002468257.1 561328 R 563178 CDS YP_002468258.1 219681872 7262281 complement(561970..563154) 1 NC_011833.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 563154 tufB 7262281 tufB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) elongation factor Tu YP_002468258.1 561970 R 563178 CDS YP_002468259.1 219681873 7262282 complement(563222..565330) 1 NC_011833.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 565330 fusA 7262282 fusA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) elongation factor G YP_002468259.1 563222 R 563178 CDS YP_002468260.1 219681874 7262283 complement(565445..565915) 1 NC_011833.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 565915 rpsG 7262283 rpsG Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S7 YP_002468260.1 565445 R 563178 CDS YP_002468261.1 219681875 7262284 complement(565957..566331) 1 NC_011833.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 566331 rpsL 7262284 rpsL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S12 YP_002468261.1 565957 R 563178 CDS YP_002468262.1 219681876 7262285 complement(566465..566752) 1 NC_011833.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 566752 yheL 7262285 yheL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfur transfer complex subunit TusB YP_002468262.1 566465 R 563178 CDS YP_002468263.1 219681877 7262286 complement(566764..567123) 1 NC_011833.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 567123 yheM 7262286 yheM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfur relay protein TusC YP_002468263.1 566764 R 563178 CDS YP_002468264.1 219681878 7262287 complement(567142..567528) 1 NC_011833.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 567528 yheN 7262287 yheN Buchnera aphidicola str. 5A (Acyrthosiphon pisum) sulfur transfer complex subunit TusD YP_002468264.1 567142 R 563178 CDS YP_002468265.1 219681879 7262288 complement(567611..568336) 1 NC_011833.1 FKBP-type peptidyl-prolyl cis-trans isomerase FkpA 568336 fkpA 7262288 fkpA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) FKBP-type peptidyl-prolyl cis-trans isomerase FkpA YP_002468265.1 567611 R 563178 CDS YP_002468266.1 219681880 7262289 complement(568798..570024) 1 NC_011833.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 570024 argD 7262289 argD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein YP_002468266.1 568798 R 563178 CDS YP_002468267.1 219681881 7262290 570341..571507 1 NC_011833.1 hypothetical protein 571507 yhfC 7262290 yhfC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468267.1 570341 D 563178 CDS YP_002468268.1 219681882 7262291 complement(571569..572576) 1 NC_011833.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 572576 trpS 7262291 trpS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tryptophanyl-tRNA synthetase YP_002468268.1 571569 R 563178 CDS YP_002468269.1 219681883 7262292 complement(572599..573285) 1 NC_011833.1 ribulose-5-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 573285 rpe 7262292 rpe Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ribulose-phosphate 3-epimerase YP_002468269.1 572599 R 563178 CDS YP_002468270.1 219681884 7262293 complement(574168..575259) 1 NC_011833.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 575259 aroB 7262293 aroB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 3-dehydroquinate synthase YP_002468270.1 574168 R 563178 CDS YP_002468271.1 219681885 7262294 complement(575277..575798) 1 NC_011833.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 575798 aroK 7262294 aroK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) shikimate kinase I YP_002468271.1 575277 R 563178 CDS YP_002468272.1 219681886 7262296 complement(576401..577105) 1 NC_011833.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 577105 deoD 7262296 deoD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) purine nucleoside phosphorylase YP_002468272.1 576401 R 563178 CDS YP_002468273.1 219681887 7262297 complement(577149..578372) 1 NC_011833.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 578372 deoB 7262297 deoB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphopentomutase YP_002468273.1 577149 R 563178 CDS YP_002468274.1 219681888 7262298 complement(578432..580012) 1 NC_011833.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 580012 prfC 7262298 prfC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) peptide chain release factor 3 YP_002468274.1 578432 R 563178 CDS YP_002468275.1 219681889 7262299 complement(581124..581702) 1 NC_011833.1 iron-sulfur cluster scaffold protein (YhgI) 581702 nfuA 7262299 nfuA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) iron-sulfur cluster scaffold protein (YhgI) YP_002468275.1 581124 R 563178 CDS YP_002468276.1 219681890 7262300 complement(582315..582830) 1 NC_011833.1 single-strand binding protein 582830 ssb 7262300 ssb Buchnera aphidicola str. 5A (Acyrthosiphon pisum) single-strand binding protein YP_002468276.1 582315 R 563178 CDS YP_002468277.1 219681891 7262301 583500..584897 1 NC_011833.1 primary replicative DNA helicase; replicative DNA helicase 584897 dnaB 7262301 dnaB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) replicative DNA helicase YP_002468277.1 583500 D 563178 CDS YP_002468278.1 219681892 7262302 585144..586106 1 NC_011833.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 586106 gshB 7262302 gshB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutathione synthetase YP_002468278.1 585144 D 563178 CDS YP_002468279.1 219681893 7262303 586117..586524 1 NC_011833.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 586524 yqgF 7262303 yqgF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) Holliday junction resolvase-like protein YP_002468279.1 586117 D 563178 CDS YP_002468280.1 219681894 7262304 586642..587244 1 NC_011833.1 hypothetical protein 587244 yggS 7262304 yggS Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468280.1 586642 D 563178 CDS YP_002468281.1 219681895 7262305 587287..588417 1 NC_011833.1 coproporphyrinogen III oxidase, anaerobic; oxidoreductase (YggW) 588417 yggW 7262305 yggW Buchnera aphidicola str. 5A (Acyrthosiphon pisum) oxidoreductase (YggW) YP_002468281.1 587287 D 563178 CDS YP_002468282.1 219681896 7262306 complement(588424..589143) 1 NC_011833.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 589143 trmB 7262306 trmB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA (guanine-N(7)-)-methyltransferase YP_002468282.1 588424 R 563178 CDS YP_002468283.1 219681897 7262307 589241..590293 1 NC_011833.1 A/G-specific DNA-adenine glycosylase; A/G-specific adenine glycosylase 590293 mutY 7262307 mutY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) A/G-specific adenine glycosylase YP_002468283.1 589241 D 563178 CDS YP_002468284.1 219681898 7262308 590265..590546 1 NC_011833.1 hypothetical protein 590546 yggX 7262308 yggX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468284.1 590265 D 563178 CDS YP_002468285.1 219681899 7262309 590640..591428 1 NC_011833.1 glutamate racemase 591428 murI 7262309 murI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glutamate racemase YP_002468285.1 590640 D 563178 CDS YP_002468286.1 219681900 7262311 592941..593249 1 NC_011833.1 hypothetical protein 593249 yeeX 7262311 yeeX Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468286.1 592941 D 563178 CDS YP_002468287.1 219681901 7262314 593630..594271 1 NC_011833.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 594271 pyrE 7262314 pyrE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) orotate phosphoribosyltransferase YP_002468287.1 593630 D 563178 CDS YP_002468288.1 219681902 7262315 complement(594283..594747) 1 NC_011833.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 594747 dut 7262315 dut Buchnera aphidicola str. 5A (Acyrthosiphon pisum) deoxyuridine 5'-triphosphate nucleotidohydrolase YP_002468288.1 594283 R 563178 CDS YP_002468289.1 219681903 7262316 complement(594791..595588) 1 NC_011833.1 CysQ protein 595588 cysQ 7262316 cysQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) CysQ protein YP_002468289.1 594791 R 563178 CDS YP_002468290.1 219681904 7262317 complement(595575..596027) 1 NC_011833.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 596027 rplI 7262317 rplI Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L9 YP_002468290.1 595575 R 563178 CDS YP_002468291.1 219681905 7262318 complement(596076..596303) 1 NC_011833.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 596303 rpsR 7262318 rpsR Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S18 YP_002468291.1 596076 R 563178 CDS YP_002468292.1 219681906 7262319 complement(596429..596770) 1 NC_011833.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 596770 rpsF 7262319 rpsF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 30S ribosomal protein S6 YP_002468292.1 596429 R 563178 CDS YP_002468293.1 219681907 7262320 complement(596936..599173) 1 NC_011833.1 RNAse R; VacB protein 599173 vacB 7262320 vacB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) VacB protein YP_002468293.1 596936 R 563178 CDS YP_002468294.1 219681908 7262321 complement(599261..600562) 1 NC_011833.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 600562 purA 7262321 purA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) adenylosuccinate synthetase YP_002468294.1 599261 R 563178 CDS YP_002468295.1 219681909 7262322 complement(600612..601544) 1 NC_011833.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 601544 hflC 7262322 hflC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) FtsH protease regulator HflC YP_002468295.1 600612 R 563178 CDS YP_002468296.1 219681910 7262323 complement(601547..602767) 1 NC_011833.1 HflK protein 602767 hflK 7262323 hflK Buchnera aphidicola str. 5A (Acyrthosiphon pisum) HflK protein YP_002468296.1 601547 R 563178 CDS YP_002468297.1 219681911 7262324 complement(602924..603832) 1 NC_011833.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 603832 miaA 7262324 miaA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) tRNA delta(2)-isopentenylpyrophosphate transferase YP_002468297.1 602924 R 563178 CDS YP_002468298.1 219681912 7262325 complement(603870..605624) 1 NC_011833.1 DNA mismatch repair protein MutL 605624 mutL 7262325 mutL Buchnera aphidicola str. 5A (Acyrthosiphon pisum) DNA mismatch repair protein MutL YP_002468298.1 603870 R 563178 CDS YP_002468299.1 219681913 7262326 complement(605724..606881) 1 NC_011833.1 D-mannitol 1-phosphate 5-dehydrogenase; mannitol-1-phosphate 5-dehydrogenase 606881 mtlD 7262326 mtlD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) mannitol-1-phosphate 5-dehydrogenase YP_002468299.1 605724 R 563178 CDS YP_002468300.1 219681914 7262327 complement(606923..608821) 1 NC_011833.1 PTS system mannitol-specific transporter subunit IIABC 608821 mtlA 7262327 mtlA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) PTS system mannitol-specific transporter subunit IIABC YP_002468300.1 606923 R 563178 CDS YP_002468301.1 219681915 7262328 complement(608995..610644) 1 NC_011833.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 610644 pgi 7262328 pgi Buchnera aphidicola str. 5A (Acyrthosiphon pisum) glucose-6-phosphate isomerase YP_002468301.1 608995 R 563178 CDS YP_002468302.1 219681916 7262329 610958..611512 1 NC_011833.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 611512 orn 7262329 orn Buchnera aphidicola str. 5A (Acyrthosiphon pisum) oligoribonuclease YP_002468302.1 610958 D 563178 CDS YP_002468303.1 219681917 7262331 611965..612678 1 NC_011833.1 N-acetylmuramoyl-L-alanine amidase 612678 amiB 7262331 amiB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) N-acetylmuramoyl-L-alanine amidase YP_002468303.1 611965 D 563178 CDS YP_002468304.1 219681918 7262332 complement(612785..613003) 1 NC_011833.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 613003 rpmE 7262332 rpmE Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 50S ribosomal protein L31 YP_002468304.1 612785 R 563178 CDS YP_002468305.1 219681919 7262333 613609..614121 1 NC_011833.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 614121 hslV 7262333 hslV Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent protease peptidase subunit YP_002468305.1 613609 D 563178 CDS YP_002468306.1 219681920 7262334 614134..615465 1 NC_011833.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 615465 hslU 7262334 hslU Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent protease ATP-binding subunit HslU YP_002468306.1 614134 D 563178 CDS YP_002468307.1 219681921 7262335 615672..616145 1 NC_011833.1 16 kDa heat shock protein A 616145 ibpA 7262335 ibpA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) 16 kDa heat shock protein A YP_002468307.1 615672 D 563178 CDS YP_002468308.1 219681922 7262336 616222..616980 1 NC_011833.1 ferredoxin-NADP reductase 616980 fpr 7262336 fpr Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ferredoxin-NADP reductase YP_002468308.1 616222 D 563178 CDS YP_002468309.1 219681923 7262337 complement(616998..617972) 1 NC_011833.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 617972 yjeA 7262337 yjeA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) lysyl-tRNA synthetase YP_002468309.1 616998 R 563178 CDS YP_002468310.1 219681924 7262338 618043..618540 1 NC_011833.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 618540 coaD 7262338 coaD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) phosphopantetheine adenylyltransferase YP_002468310.1 618043 D 563178 CDS YP_002468311.1 219681925 7262339 complement(618627..619730) 1 NC_011833.1 hypothetical protein 619730 yba3 7262339 yba3 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468311.1 618627 R 563178 CDS YP_002468312.1 219681926 7262340 complement(619723..620061) 1 NC_011833.1 hypothetical protein 620061 yba4 7262340 yba4 Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468312.1 619723 R 563178 CDS YP_002468313.1 219681927 7262341 620217..620957 1 NC_011833.1 SAM-dependent methyltransferase (YhiQ) 620957 yhiQ 7262341 yhiQ Buchnera aphidicola str. 5A (Acyrthosiphon pisum) SAM-dependent methyltransferase (YhiQ) YP_002468313.1 620217 D 563178 CDS YP_002468314.1 219681928 7262342 complement(621040..622512) 1 NC_011833.1 low-affinity inorganic phosphate transporter 622512 pitA 7262342 pitA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) low-affinity inorganic phosphate transporter YP_002468314.1 621040 R 563178 CDS YP_002468315.1 219681929 7262344 complement(623931..624785) 1 NC_011833.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 624785 dapF 7262344 dapF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) diaminopimelate epimerase YP_002468315.1 623931 R 563178 CDS YP_002468316.1 219681930 7262345 624974..625324 1 NC_011833.1 CyaY protein 625324 cyaY 7262345 cyaY Buchnera aphidicola str. 5A (Acyrthosiphon pisum) CyaY protein YP_002468316.1 624974 D 563178 CDS YP_002468317.1 219681931 7262346 625453..626397 1 NC_011833.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 626397 hemC 7262346 hemC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) porphobilinogen deaminase YP_002468317.1 625453 D 563178 CDS YP_002468318.1 219681932 7262715 complement(627635..628894) 1 NC_011833.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 628894 rho 7262715 rho Buchnera aphidicola str. 5A (Acyrthosiphon pisum) transcription termination factor Rho YP_002468318.1 627635 R 563178 CDS YP_002468319.1 219681933 7262716 complement(629024..629350) 1 NC_011833.1 thioredoxin 629350 trxA 7262716 trxA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) thioredoxin YP_002468319.1 629024 R 563178 CDS YP_002468320.1 219681934 7262717 complement(629552..631489) 1 NC_011833.1 ATP-dependent DNA helicase Rep 631489 rep 7262717 rep Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ATP-dependent DNA helicase Rep YP_002468320.1 629552 R 563178 CDS YP_002468321.1 219681935 7262718 complement(631559..633031) 1 NC_011833.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 633031 ilvC 7262718 ilvC Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ketol-acid reductoisomerase YP_002468321.1 631559 R 563178 CDS YP_002468322.1 219681936 7262719 complement(633079..634932) 1 NC_011833.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 634932 ilvD 7262719 ilvD Buchnera aphidicola str. 5A (Acyrthosiphon pisum) dihydroxy-acid dehydratase YP_002468322.1 633079 R 563178 CDS YP_002468323.1 219681937 7262721 635421..636635 1 NC_011833.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 636635 mitF 7262721 mitF Buchnera aphidicola str. 5A (Acyrthosiphon pisum) cysteine desulfurase YP_002468323.1 635421 D 563178 CDS YP_002468324.1 219681938 7262722 636666..637049 1 NC_011833.1 scaffold protein 637049 iscU 7262722 iscU Buchnera aphidicola str. 5A (Acyrthosiphon pisum) scaffold protein YP_002468324.1 636666 D 563178 CDS YP_002468325.1 219681939 7262723 637144..637668 1 NC_011833.1 chaperone protein HscB 637668 hscB 7262723 hscB Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chaperone protein HscB YP_002468325.1 637144 D 563178 CDS YP_002468326.1 219681940 7262724 637680..639515 1 NC_011833.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 639515 hscA 7262724 hscA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) chaperone protein HscA YP_002468326.1 637680 D 563178 CDS YP_002468327.1 219681941 7262725 639515..639850 1 NC_011833.1 ferredoxin 2fe-2s 639850 fdx 7262725 fdx Buchnera aphidicola str. 5A (Acyrthosiphon pisum) ferredoxin 2fe-2s YP_002468327.1 639515 D 563178 CDS YP_002468328.1 219681942 7262726 complement(639847..641208) 1 NC_011833.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 641208 engA 7262726 engA Buchnera aphidicola str. 5A (Acyrthosiphon pisum) GTP-binding protein EngA YP_002468328.1 639847 R 563178 CDS YP_002468329.1 219681943 7262727 complement(641301..641882) 1 NC_011833.1 hypothetical protein 641882 yfgM 7262727 yfgM Buchnera aphidicola str. 5A (Acyrthosiphon pisum) hypothetical protein YP_002468329.1 641301 R 563178 CDS