-- dump date 20140619_011822 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_057962.1 10957100 1109444 1..1566 1 NC_002252.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I 1566 trpE 1109444 trpE Buchnera aphidicola str. APS (Acyrthosiphon pisum) anthranilate synthase component I NP_057962.1 1 D 107806 CDS NP_057963.1 10957101 1109446 1569..2171 1 NC_002252.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 2171 trpG 1109446 trpG Buchnera aphidicola str. APS (Acyrthosiphon pisum) anthranilate synthase component II NP_057963.1 1569 D 107806 CDS NP_057964.1 10957102 1109447 5199..5801 1 NC_002252.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II 5801 trpG2 1109447 trpG2 Buchnera aphidicola str. APS (Acyrthosiphon pisum) anthranilate synthase component II NP_057964.1 5199 D 107806 CDS NP_057965.1 10957104 1109453 complement(346..1197) 1 NC_002253.1 replication-associated protein RepA1 1197 repA1 1109453 repA1 Buchnera aphidicola str. APS (Acyrthosiphon pisum) replication-associated protein RepA1 NP_057965.1 346 R 107806 CDS NP_057966.1 10957105 1109454 1514..2017 1 NC_002253.1 hypothetical protein 2017 yqhA 1109454 yqhA Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_057966.1 1514 D 107806 CDS NP_057967.1 10957106 1109448 2357..2893 1 NC_002253.1 replication-associated protein RepA2 2893 RepA2 1109448 RepA2 Buchnera aphidicola str. APS (Acyrthosiphon pisum) replication-associated protein RepA2 NP_057967.1 2357 D 107806 CDS NP_057968.1 10957107 1109449 3032..4591 1 NC_002253.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 4591 leuA 1109449 leuA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2-isopropylmalate synthase NP_057968.1 3032 D 107806 CDS NP_057969.1 10957108 1109450 4652..5743 1 NC_002253.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 5743 leuB 1109450 leuB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-isopropylmalate dehydrogenase NP_057969.1 4652 D 107806 CDS NP_057970.1 10957109 1109451 5733..7160 1 NC_002253.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; isopropylmalate isomerase large subunit 7160 leuC 1109451 leuC Buchnera aphidicola str. APS (Acyrthosiphon pisum) isopropylmalate isomerase large subunit NP_057970.1 5733 D 107806 CDS NP_057971.1 10957110 1109452 7163..7786 1 NC_002253.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; isopropylmalate isomerase small subunit 7786 leuD 1109452 leuD Buchnera aphidicola str. APS (Acyrthosiphon pisum) isopropylmalate isomerase small subunit NP_057971.1 7163 D 107806 CDS NP_239843.1 15616631 1109510 197..2083 1 NC_002528.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 2083 gidA 1109510 gidA Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA uridine 5-carboxymethylaminomethyl modification protein GidA NP_239843.1 197 D 107806 CDS NP_239844.1 15616632 1109511 2278..3102 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase F0F1 subunit A 3102 atpB 1109511 atpB Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit A NP_239844.1 2278 D 107806 CDS NP_239845.1 15616633 1109512 3139..3378 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase F0F1 subunit C 3378 atpE 1109512 atpE Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit C NP_239845.1 3139 D 107806 CDS NP_239846.1 15616634 1109513 3497..3982 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase F0F1 subunit B 3982 atpF 1109513 atpF Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit B NP_239846.1 3497 D 107806 CDS NP_239847.1 15616635 1109514 3982..4515 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase F0F1 subunit delta 4515 atpH 1109514 atpH Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit delta NP_239847.1 3982 D 107806 CDS NP_239848.1 15616636 1109515 4530..6068 1 NC_002528.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase F0F1 subunit alpha 6068 atpA 1109515 atpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit alpha NP_239848.1 4530 D 107806 CDS NP_239849.1 15616637 1109516 6101..6973 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase F0F1 subunit gamma 6973 atpG 1109516 atpG Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit gamma NP_239849.1 6101 D 107806 CDS NP_239850.1 15616638 1109517 6997..8394 1 NC_002528.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase F0F1 subunit beta 8394 atpD 1109517 atpD Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit beta NP_239850.1 6997 D 107806 CDS NP_239851.1 15616639 1109518 8421..8837 1 NC_002528.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase F0F1 subunit epsilon 8837 atpC 1109518 atpC Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP synthase F0F1 subunit epsilon NP_239851.1 8421 D 107806 CDS NP_239852.1 15616640 1109519 complement(8911..11322) 1 NC_002528.1 DNA gyrase subunit B 11322 gyrB 1109519 gyrB Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA gyrase subunit B NP_239852.1 8911 R 107806 CDS NP_239853.1 15616641 1109520 complement(11449..12549) 1 NC_002528.1 DNA polymerase III beta chain 12549 dnaN 1109520 dnaN Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III beta chain NP_239853.1 11449 R 107806 CDS NP_239854.1 15616642 1109521 complement(12554..13918) 1 NC_002528.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosome replication initiator DnaA 13918 dnaA 1109521 dnaA Buchnera aphidicola str. APS (Acyrthosiphon pisum) chromosome replication initiator DnaA NP_239854.1 12554 R 107806 CDS NP_239855.1 15616643 1109522 14369..14512 1 NC_002528.1 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 14512 rpmH 1109522 rpmH Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L34 NP_239855.1 14369 D 107806 CDS NP_239856.1 15616644 1109523 14525..14872 1 NC_002528.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P 14872 rnpA 1109523 rnpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonuclease P NP_239856.1 14525 D 107806 CDS NP_239857.1 15616645 1109524 15011..16609 1 NC_002528.1 hypothetical protein 16609 yidC 1109524 yidC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239857.1 15011 D 107806 CDS NP_239858.2 28952039 1109525 16648..18009 1 NC_002528.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 18009 trmE 1109525 trmE Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA modification GTPase TrmE NP_239858.2 16648 D 107806 CDS NP_239859.1 15616647 1109526 18376..18666 1 NC_002528.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 18666 groES 1109526 groES Buchnera aphidicola str. APS (Acyrthosiphon pisum) co-chaperonin GroES NP_239859.1 18376 D 107806 CDS NP_239860.1 15616648 1109527 18715..20361 1 NC_002528.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; molecular chaperone GroEL 20361 groEL 1109527 groEL Buchnera aphidicola str. APS (Acyrthosiphon pisum) molecular chaperone GroEL NP_239860.1 18715 D 107806 CDS NP_239861.1 15616649 1109528 20985..21596 1 NC_002528.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 21596 efp 1109528 efp Buchnera aphidicola str. APS (Acyrthosiphon pisum) elongation factor P NP_239861.1 20985 D 107806 CDS NP_239862.1 15616650 1109529 complement(21614..22354) 1 NC_002528.1 acts to load the DnaB helicase onto the initiation site during DNA replication; DNA replication protein DnaC 22354 dnaC 1109529 dnaC Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA replication protein DnaC NP_239862.1 21614 R 107806 CDS NP_239863.1 15616651 1109530 complement(22354..22848) 1 NC_002528.1 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'; primosomal protein DnaI 22848 dnaT 1109530 dnaT Buchnera aphidicola str. APS (Acyrthosiphon pisum) primosomal protein DnaI NP_239863.1 22354 R 107806 CDS NP_239864.1 15616652 1109531 complement(22945..23520) 1 NC_002528.1 hypothetical protein 23520 yhhF 1109531 yhhF Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239864.1 22945 R 107806 CDS NP_239865.1 15616653 1109532 23651..24787 1 NC_002528.1 cell division protein FtsY 24787 ftsY 1109532 ftsY Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsY NP_239865.1 23651 D 107806 CDS NP_239866.1 15616654 1109533 24950..25804 1 NC_002528.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters; RNA polymerase factor sigma-32 25804 rpoH 1109533 rpoH Buchnera aphidicola str. APS (Acyrthosiphon pisum) RNA polymerase factor sigma-32 NP_239866.1 24950 D 107806 CDS NP_239867.2 28952040 1109534 complement(25945..27774) 1 NC_002528.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 27774 glmS 1109534 glmS Buchnera aphidicola str. APS (Acyrthosiphon pisum) glucosamine--fructose-6-phosphate aminotransferase NP_239867.2 25945 R 107806 CDS NP_239868.1 15616656 1109535 complement(27844..29223) 1 NC_002528.1 UDP-N-acetylglucosamine pyrophosphorylase 29223 glmU 1109535 glmU Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylglucosamine pyrophosphorylase NP_239868.1 27844 R 107806 CDS NP_239869.1 15616657 1109536 29403..29972 1 NC_002528.1 hypothetical protein 29972 yigL 1109536 yigL Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239869.1 29403 D 107806 CDS NP_239870.1 15616658 1109537 30011..30220 1 NC_002528.1 Cof protein 30220 cof 1109537 cof Buchnera aphidicola str. APS (Acyrthosiphon pisum) Cof protein NP_239870.1 30011 D 107806 CDS NP_239871.1 15616659 1109538 31191..33467 1 NC_002528.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 33467 metE 1109538 metE Buchnera aphidicola str. APS (Acyrthosiphon pisum) 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase NP_239871.1 31191 D 107806 CDS NP_239872.1 15616660 1109539 complement(33590..35167) 1 NC_002528.1 involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 35167 purH 1109539 purH Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase NP_239872.1 33590 R 107806 CDS NP_239873.1 15616661 1109540 complement(35308..35586) 1 NC_002528.1 DNA-binding protein HU-alpha 35586 hupA 1109540 hupA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA-binding protein HU-alpha NP_239873.1 35308 R 107806 CDS NP_239874.1 15616662 1109541 complement(36321..40544) 1 NC_002528.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 40544 rpoC 1109541 rpoC Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit beta' NP_239874.1 36321 R 107806 CDS NP_239875.1 15616663 1109542 complement(40622..44650) 1 NC_002528.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 44650 rpoB 1109542 rpoB Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit beta NP_239875.1 40622 R 107806 CDS NP_239876.1 15616664 1109543 complement(44871..45239) 1 NC_002528.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 45239 rplL 1109543 rplL Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L7/L12 NP_239876.1 44871 R 107806 CDS NP_239877.1 15616665 1109544 complement(45306..45803) 1 NC_002528.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 45803 rplJ 1109544 rplJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L10 NP_239877.1 45306 R 107806 CDS NP_239878.1 15616666 1109545 complement(46069..46764) 1 NC_002528.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 46764 rplA 1109545 rplA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L1 NP_239878.1 46069 R 107806 CDS NP_239879.1 15616667 1109546 complement(46767..47195) 1 NC_002528.1 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 47195 rplK 1109546 rplK Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L11 NP_239879.1 46767 R 107806 CDS NP_239880.1 15616668 1109547 complement(47243..47788) 1 NC_002528.1 transcription antitermination protein NusG 47788 nusG 1109547 nusG Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription antitermination protein NusG NP_239880.1 47243 R 107806 CDS NP_239881.1 15616669 1109548 complement(47791..48174) 1 NC_002528.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 48174 secE 1109548 secE Buchnera aphidicola str. APS (Acyrthosiphon pisum) preprotein translocase subunit SecE NP_239881.1 47791 R 107806 CDS NP_239882.1 15616670 1109549 complement(48981..50051) 1 NC_002528.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 50051 murB 1109549 murB Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylenolpyruvoylglucosamine reductase NP_239882.1 48981 R 107806 CDS NP_239883.1 15616671 1109550 50166..51044 1 NC_002528.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor; 5,10-methylenetetrahydrofolate reductase 51044 metF 1109550 metF Buchnera aphidicola str. APS (Acyrthosiphon pisum) 5,10-methylenetetrahydrofolate reductase NP_239883.1 50166 D 107806 CDS NP_239884.1 15616672 1109551 complement(51056..52201) 1 NC_002528.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; acetylornithine deacetylase 52201 argE 1109551 argE Buchnera aphidicola str. APS (Acyrthosiphon pisum) acetylornithine deacetylase NP_239884.1 51056 R 107806 CDS NP_239885.1 15616673 1109455 52362..53366 1 NC_002528.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 53366 argC 1109455 argC Buchnera aphidicola str. APS (Acyrthosiphon pisum) N-acetyl-gamma-glutamyl-phosphate reductase NP_239885.1 52362 D 107806 CDS NP_239886.1 15616674 1109456 53387..54160 1 NC_002528.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 54160 argB 1109456 argB Buchnera aphidicola str. APS (Acyrthosiphon pisum) acetylglutamate kinase NP_239886.1 53387 D 107806 CDS NP_239887.1 15616675 1109457 54190..55401 1 NC_002528.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 55401 argG 1109457 argG Buchnera aphidicola str. APS (Acyrthosiphon pisum) argininosuccinate synthase NP_239887.1 54190 D 107806 CDS NP_239888.1 15616676 1109458 55473..56852 1 NC_002528.1 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 56852 argH 1109458 argH Buchnera aphidicola str. APS (Acyrthosiphon pisum) argininosuccinate lyase NP_239888.1 55473 D 107806 CDS NP_239889.1 15616677 1109459 56934..57368 1 NC_002528.1 hypothetical protein 57368 yibN 1109459 yibN Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239889.1 56934 D 107806 CDS NP_239890.1 15616678 1109460 57475..57903 1 NC_002528.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 57903 secB 1109460 secB Buchnera aphidicola str. APS (Acyrthosiphon pisum) preprotein translocase subunit SecB NP_239890.1 57475 D 107806 CDS NP_239891.1 15616679 1109461 58005..58829 1 NC_002528.1 serine acetyltransferase 58829 cysE 1109461 cysE Buchnera aphidicola str. APS (Acyrthosiphon pisum) serine acetyltransferase NP_239891.1 58005 D 107806 CDS NP_239892.1 15616680 1109462 complement(58935..60773) 1 NC_002528.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria; RNA polymerase sigma factor RpoD 60773 rpoD 1109462 rpoD Buchnera aphidicola str. APS (Acyrthosiphon pisum) RNA polymerase sigma factor RpoD NP_239892.1 58935 R 107806 CDS NP_239893.1 15616681 1109463 complement(60941..62674) 1 NC_002528.1 DNA primase 62674 dnaG 1109463 dnaG Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA primase NP_239893.1 60941 R 107806 CDS NP_239894.1 15616682 1109464 complement(62755..62970) 1 NC_002528.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 62970 rpsU 1109464 rpsU Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S21 NP_239894.1 62755 R 107806 CDS NP_239895.1 15616683 1109465 63204..64214 1 NC_002528.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; putative DNA-binding/iron metalloprotein/AP endonuclease 64214 ygjD 1109465 ygjD Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative DNA-binding/iron metalloprotein/AP endonuclease NP_239895.1 63204 D 107806 CDS NP_239896.1 15616684 1109466 complement(64192..64839) 1 NC_002528.1 DHBP synthase; functions during riboflavin biosynthesis; 3,4-dihydroxy-2-butanone 4-phosphate synthase 64839 ribB 1109466 ribB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3,4-dihydroxy-2-butanone 4-phosphate synthase NP_239896.1 64192 R 107806 CDS NP_239897.1 15616685 1109467 complement(65111..66058) 1 NC_002528.1 kinase 66058 yb3052 1109467 yb3052 Buchnera aphidicola str. APS (Acyrthosiphon pisum) kinase NP_239897.1 65111 R 107806 CDS NP_239898.1 15616686 1109468 66272..67516 1 NC_002528.1 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase 67516 cca 1109468 cca Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA CCA-pyrophosphorylase NP_239898.1 66272 D 107806 CDS NP_239899.1 15616687 1109469 complement(67542..68339) 1 NC_002528.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; UDP pyrophosphate phosphatase 68339 bacA 1109469 bacA Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP pyrophosphate phosphatase NP_239899.1 67542 R 107806 CDS NP_239900.1 15616688 1109470 complement(68425..68910) 1 NC_002528.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose; PTS system glucose-specific transporter 68910 crr 1109470 crr Buchnera aphidicola str. APS (Acyrthosiphon pisum) PTS system glucose-specific transporter NP_239900.1 68425 R 107806 CDS NP_239901.1 15616689 1109471 complement(68960..70675) 1 NC_002528.1 Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system; phosphoenolpyruvate-protein phosphotransferase 70675 ptsI 1109471 ptsI Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoenolpyruvate-protein phosphotransferase NP_239901.1 68960 R 107806 CDS NP_239902.1 15616690 1109472 complement(70824..71081) 1 NC_002528.1 phosphocarrier protein HPr 71081 ptsH 1109472 ptsH Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphocarrier protein HPr NP_239902.1 70824 R 107806 CDS NP_239903.1 15616691 1109473 complement(71230..72177) 1 NC_002528.1 cysteine synthase A 72177 cysK 1109473 cysK Buchnera aphidicola str. APS (Acyrthosiphon pisum) cysteine synthase A NP_239903.1 71230 R 107806 CDS NP_239904.1 15616692 1109474 72432..74459 1 NC_002528.1 DNA ligase 74459 lig 1109474 lig Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA ligase NP_239904.1 72432 D 107806 CDS NP_239905.1 15616693 1109475 74771..76174 1 NC_002528.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 76174 gltX 1109475 gltX Buchnera aphidicola str. APS (Acyrthosiphon pisum) glutamyl-tRNA synthetase NP_239905.1 74771 D 107806 CDS NP_239906.1 15616694 1109476 complement(76514..76810) 1 NC_002528.1 flagellar hook-basal body complex protein FliE 76810 fliE 1109476 fliE Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar hook-basal body complex protein FliE NP_239906.1 76514 R 107806 CDS NP_239907.1 15616695 1109477 77074..78711 1 NC_002528.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar MS-ring protein 78711 fliF 1109477 fliF Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar MS-ring protein NP_239907.1 77074 D 107806 CDS NP_239908.1 15616696 1109478 78708..79703 1 NC_002528.1 flagellar motor switch protein FliG 79703 fliG 1109478 fliG Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar motor switch protein FliG NP_239908.1 78708 D 107806 CDS NP_239909.1 15616697 1109479 79696..80358 1 NC_002528.1 flagellar assembly protein FliH 80358 fliH 1109479 fliH Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar assembly protein FliH NP_239909.1 79696 D 107806 CDS NP_239910.1 15616698 1109480 80316..81719 1 NC_002528.1 flagellum-specific ATP synthase 81719 fliI 1109480 fliI Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellum-specific ATP synthase NP_239910.1 80316 D 107806 CDS NP_239911.1 15616699 1109481 81749..82186 1 NC_002528.1 flagellar FliJ protein 82186 fliJ 1109481 fliJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar FliJ protein NP_239911.1 81749 D 107806 CDS NP_239913.1 15616701 1109483 82624..83331 1 NC_002528.1 flagellar hook-length control protein 83331 fliK 1109483 fliK Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar hook-length control protein NP_239913.1 82624 D 107806 CDS NP_239914.1 15616702 1109484 83392..84339 1 NC_002528.1 flagellar motor switch protein FliM 84339 fliM 1109484 fliM Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar motor switch protein FliM NP_239914.1 83392 D 107806 CDS NP_239915.1 15616703 1109485 84332..84733 1 NC_002528.1 flagellar motor switch protein FliN 84733 fliN 1109485 fliN Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar motor switch protein FliN NP_239915.1 84332 D 107806 CDS NP_239916.1 15616704 1109486 84745..85884 1 NC_002528.1 putative bifunctional flagellar biosynthesis protein FliO/FliP 85884 fliP 1109486 fliP Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative bifunctional flagellar biosynthesis protein FliO/FliP NP_239916.1 84745 D 107806 CDS NP_239917.1 15616705 1109487 85956..86225 1 NC_002528.1 flagellar biosynthetic protein FliQ 86225 fliQ 1109487 fliQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar biosynthetic protein FliQ NP_239917.1 85956 D 107806 CDS NP_239918.1 15616706 1109488 86225..87001 1 NC_002528.1 flagellar biosynthetic protein FliR 87001 fliR 1109488 fliR Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar biosynthetic protein FliR NP_239918.1 86225 D 107806 CDS NP_239919.1 15616707 1109489 complement(87154..87321) 1 NC_002528.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 87321 rpmG 1109489 rpmG Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L33 NP_239919.1 87154 R 107806 CDS NP_239920.1 15616708 1109490 complement(87332..87559) 1 NC_002528.1 required for 70S ribosome assembly; 50S ribosomal protein L28 87559 rpmB 1109490 rpmB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L28 NP_239920.1 87332 R 107806 CDS NP_239921.1 15616709 1109491 87905..90817 1 NC_002528.1 hypothetical protein 90817 ytfN 1109491 ytfN Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239921.1 87905 D 107806 CDS NP_239922.1 15616710 1109492 complement(90833..91381) 1 NC_002528.1 catalyzes the hydrolysis of pyrophosphate to phosphate; inorganic pyrophosphatase 91381 ppa 1109492 ppa Buchnera aphidicola str. APS (Acyrthosiphon pisum) inorganic pyrophosphatase NP_239922.1 90833 R 107806 CDS NP_239923.1 15616711 1109493 91575..92915 1 NC_002528.1 PmbA protein 92915 pmbA 1109493 pmbA Buchnera aphidicola str. APS (Acyrthosiphon pisum) PmbA protein NP_239923.1 91575 D 107806 CDS NP_239924.1 15616712 1109494 complement(93393..94241) 1 NC_002528.1 hypothetical protein 94241 yraL 1109494 yraL Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239924.1 93393 R 107806 CDS NP_239925.1 15616713 1109495 94380..95600 1 NC_002528.1 3-oxoacyl-ACP synthase 95600 fabB 1109495 fabB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-oxoacyl-ACP synthase NP_239925.1 94380 D 107806 CDS NP_239926.1 15616714 1109496 95840..96790 1 NC_002528.1 Maintains the balance of metabolites in the pentose-phosphate pathway; transaldolase B 96790 talA 1109496 talA Buchnera aphidicola str. APS (Acyrthosiphon pisum) transaldolase B NP_239926.1 95840 D 107806 CDS NP_239927.1 15616715 1109497 96845..98842 1 NC_002528.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase 98842 tktB 1109497 tktB Buchnera aphidicola str. APS (Acyrthosiphon pisum) transketolase NP_239927.1 96845 D 107806 CDS NP_239928.1 15616716 1109498 98947..100074 1 NC_002528.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 100074 dapE 1109498 dapE Buchnera aphidicola str. APS (Acyrthosiphon pisum) succinyl-diaminopimelate desuccinylase NP_239928.1 98947 D 107806 CDS NP_239929.1 15616717 1109499 complement(100464..101348) 1 NC_002528.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 101348 dapA 1109499 dapA Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydrodipicolinate synthase NP_239929.1 100464 R 107806 CDS NP_239930.1 15616718 1109500 complement(101924..102988) 1 NC_002528.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 102988 aroC 1109500 aroC Buchnera aphidicola str. APS (Acyrthosiphon pisum) chorismate synthase NP_239930.1 101924 R 107806 CDS NP_239931.1 15616719 1109501 103284..103844 1 NC_002528.1 hypothetical protein 103844 yb2331 1109501 yb2331 Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239931.1 103284 D 107806 CDS NP_239932.1 15616720 1109502 104169..105068 1 NC_002528.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors; ATP phosphoribosyltransferase 105068 hisG 1109502 hisG Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP phosphoribosyltransferase NP_239932.1 104169 D 107806 CDS NP_239933.1 15616721 1109503 105077..106384 1 NC_002528.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 106384 hisD 1109503 hisD Buchnera aphidicola str. APS (Acyrthosiphon pisum) histidinol dehydrogenase NP_239933.1 105077 D 107806 CDS NP_239934.1 15616722 1109504 106381..107487 1 NC_002528.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 107487 hisC 1109504 hisC Buchnera aphidicola str. APS (Acyrthosiphon pisum) histidinol-phosphate aminotransferase NP_239934.1 106381 D 107806 CDS NP_239935.1 15616723 1109505 107477..108538 1 NC_002528.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate; imidazole glycerol-phosphate dehydratase/histidinol phosphatase 108538 hisB 1109505 hisB Buchnera aphidicola str. APS (Acyrthosiphon pisum) imidazole glycerol-phosphate dehydratase/histidinol phosphatase NP_239935.1 107477 D 107806 CDS NP_239936.1 15616724 1109506 108538..109128 1 NC_002528.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 109128 hisH 1109506 hisH Buchnera aphidicola str. APS (Acyrthosiphon pisum) imidazole glycerol phosphate synthase subunit HisH NP_239936.1 108538 D 107806 CDS NP_239937.1 15616725 1109507 109133..109873 1 NC_002528.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 109873 hisA 1109507 hisA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NP_239937.1 109133 D 107806 CDS NP_239938.1 15616726 1109508 109852..110628 1 NC_002528.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 110628 hisF 1109508 hisF Buchnera aphidicola str. APS (Acyrthosiphon pisum) imidazole glycerol phosphate synthase subunit HisF NP_239938.1 109852 D 107806 CDS NP_239939.1 15616727 1109509 110622..111269 1 NC_002528.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase 111269 hisI 1109509 hisI Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase NP_239939.1 110622 D 107806 CDS NP_239940.1 15616728 1109552 111628..113034 1 NC_002528.1 decarboxylating; catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 113034 gnd 1109552 gnd Buchnera aphidicola str. APS (Acyrthosiphon pisum) 6-phosphogluconate dehydrogenase NP_239940.1 111628 D 107806 CDS NP_239941.2 161353757 1109553 113236..113817 1 NC_002528.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 113817 dcd 1109553 dcd Buchnera aphidicola str. APS (Acyrthosiphon pisum) deoxycytidine triphosphate deaminase NP_239941.2 113236 D 107806 CDS NP_239942.1 15616730 1109554 113965..115608 1 NC_002528.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 115608 metG 1109554 metG Buchnera aphidicola str. APS (Acyrthosiphon pisum) methionyl-tRNA synthetase NP_239942.1 113965 D 107806 CDS NP_239943.1 15616731 1109555 complement(115656..116978) 1 NC_002528.1 cell cycle protein MesJ 116978 mesJ 1109555 mesJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell cycle protein MesJ NP_239943.1 115656 R 107806 CDS NP_239944.1 15616732 1109556 117204..117830 1 NC_002528.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 117830 ribE 1109556 ribE Buchnera aphidicola str. APS (Acyrthosiphon pisum) riboflavin synthase subunit alpha NP_239944.1 117204 D 107806 CDS NP_239945.1 15616733 1109557 117867..118448 1 NC_002528.1 Na(+)-translocating NADH-quinone reductase subunit E 118448 rnfA 1109557 rnfA Buchnera aphidicola str. APS (Acyrthosiphon pisum) Na(+)-translocating NADH-quinone reductase subunit E NP_239945.1 117867 D 107806 CDS NP_239946.1 15616734 1109558 118451..118954 1 NC_002528.1 ferredoxin II 118954 rnfB 1109558 rnfB Buchnera aphidicola str. APS (Acyrthosiphon pisum) ferredoxin II NP_239946.1 118451 D 107806 CDS NP_239947.1 15616735 1109559 119117..120538 1 NC_002528.1 hypothetical protein 120538 rnfC 1109559 rnfC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239947.1 119117 D 107806 CDS NP_239948.2 28952041 1109560 120586..121629 1 NC_002528.1 hypothetical protein 121629 ydgO 1109560 ydgO Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239948.2 120586 D 107806 CDS NP_239949.1 15616737 1109561 121778..122272 1 NC_002528.1 nitrogen fixation protein 122272 rnfG 1109561 rnfG Buchnera aphidicola str. APS (Acyrthosiphon pisum) nitrogen fixation protein NP_239949.1 121778 D 107806 CDS NP_239950.1 15616738 1109562 122247..122930 1 NC_002528.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase; electron transport complex protein RsxE 122930 ydgQ 1109562 ydgQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) electron transport complex protein RsxE NP_239950.1 122247 D 107806 CDS NP_239951.1 15616739 1109563 122941..123573 1 NC_002528.1 endonuclease III 123573 nth 1109563 nth Buchnera aphidicola str. APS (Acyrthosiphon pisum) endonuclease III NP_239951.1 122941 D 107806 CDS NP_239952.2 28952042 1109564 123596..125776 1 NC_002528.1 primosomal protein N' 125776 priA 1109564 priA Buchnera aphidicola str. APS (Acyrthosiphon pisum) primosomal protein N' NP_239952.2 123596 D 107806 CDS NP_239953.1 15616741 1109565 125936..127204 1 NC_002528.1 tyrosyl-tRNA synthetase 127204 tyrS 1109565 tyrS Buchnera aphidicola str. APS (Acyrthosiphon pisum) tyrosyl-tRNA synthetase NP_239953.1 125936 D 107806 CDS NP_239954.1 15616742 1109566 complement(127212..127604) 1 NC_002528.1 hypothetical protein 127604 ydiC 1109566 ydiC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239954.1 127212 R 107806 CDS NP_239955.1 15616743 1109567 127828..128910 1 NC_002528.1 YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function; putative inner membrane protein 128910 yb1688 1109567 yb1688 Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative inner membrane protein NP_239955.1 127828 D 107806 CDS NP_239956.1 15616744 1109568 129262..130308 1 NC_002528.1 Trp-sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase 130308 aroH 1109568 aroH Buchnera aphidicola str. APS (Acyrthosiphon pisum) phospho-2-dehydro-3-deoxyheptonate aldolase NP_239956.1 129262 D 107806 CDS NP_239957.1 15616745 1109569 130460..132388 1 NC_002528.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 132388 thrS 1109569 thrS Buchnera aphidicola str. APS (Acyrthosiphon pisum) threonyl-tRNA synthetase NP_239957.1 130460 D 107806 CDS NP_239958.1 15616746 1109570 132392..132931 1 NC_002528.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 132931 infC 1109570 infC Buchnera aphidicola str. APS (Acyrthosiphon pisum) translation initiation factor IF-3 NP_239958.1 132392 D 107806 CDS NP_239959.1 15616747 1109571 133018..133215 1 NC_002528.1 50S ribosomal protein L35 133215 rpmI 1109571 rpmI Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L35 NP_239959.1 133018 D 107806 CDS NP_239960.1 15616748 1109572 133258..133614 1 NC_002528.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 133614 rplT 1109572 rplT Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L20 NP_239960.1 133258 D 107806 CDS NP_239961.1 15616749 1109573 133809..134798 1 NC_002528.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 134798 pheS 1109573 pheS Buchnera aphidicola str. APS (Acyrthosiphon pisum) phenylalanyl-tRNA synthetase subunit alpha NP_239961.1 133809 D 107806 CDS NP_239962.1 15616750 1109574 134808..137195 1 NC_002528.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 137195 pheT 1109574 pheT Buchnera aphidicola str. APS (Acyrthosiphon pisum) phenylalanyl-tRNA synthetase subunit beta NP_239962.1 134808 D 107806 CDS NP_239963.1 15616751 1109575 137200..137508 1 NC_002528.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit alpha 137508 ihfA 1109575 ihfA Buchnera aphidicola str. APS (Acyrthosiphon pisum) integration host factor subunit alpha NP_239963.1 137200 D 107806 CDS NP_239964.1 15616752 1109576 137550..138623 1 NC_002528.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 138623 queA 1109576 queA Buchnera aphidicola str. APS (Acyrthosiphon pisum) S-adenosylmethionine--tRNA ribosyltransferase-isomerase NP_239964.1 137550 D 107806 CDS NP_239965.1 15616753 1109577 138664..139776 1 NC_002528.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 139776 tgt 1109577 tgt Buchnera aphidicola str. APS (Acyrthosiphon pisum) queuine tRNA-ribosyltransferase NP_239965.1 138664 D 107806 CDS NP_239966.1 15616754 1109578 139801..140136 1 NC_002528.1 hypothetical protein 140136 yajC 1109578 yajC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239966.1 139801 D 107806 CDS NP_239967.1 15616755 1109579 complement(140188..142260) 1 NC_002528.1 glycyl-tRNA synthetase subunit beta 142260 glyS 1109579 glyS Buchnera aphidicola str. APS (Acyrthosiphon pisum) glycyl-tRNA synthetase subunit beta NP_239967.1 140188 R 107806 CDS NP_239968.2 28952043 1109580 complement(142235..143173) 1 NC_002528.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 143173 glyQ 1109580 glyQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) glycyl-tRNA synthetase subunit alpha NP_239968.2 142235 R 107806 CDS NP_239969.1 15616757 1109581 143868..144713 1 NC_002528.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 144713 nfo 1109581 nfo Buchnera aphidicola str. APS (Acyrthosiphon pisum) endonuclease IV NP_239969.1 143868 D 107806 CDS NP_239970.1 15616758 1109582 144748..145035 1 NC_002528.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25 145035 rplY 1109582 rplY Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L25 NP_239970.1 144748 D 107806 CDS NP_239971.1 15616759 1109583 complement(145105..145875) 1 NC_002528.1 hypothetical protein 145875 yabI 1109583 yabI Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_239971.1 145105 R 107806 CDS NP_239972.1 15616760 1109584 146062..147354 1 NC_002528.1 survival protein SurA 147354 surA 1109584 surA Buchnera aphidicola str. APS (Acyrthosiphon pisum) survival protein SurA NP_239972.1 146062 D 107806 CDS NP_239973.1 15616761 1109585 147408..148229 1 NC_002528.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 148229 ksgA 1109585 ksgA Buchnera aphidicola str. APS (Acyrthosiphon pisum) dimethyladenosine transferase NP_239973.1 147408 D 107806 CDS NP_239974.1 15616762 1109586 148274..149098 1 NC_002528.1 symmetrical; hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP; diadenosine tetraphosphatase 149098 apaH 1109586 apaH Buchnera aphidicola str. APS (Acyrthosiphon pisum) diadenosine tetraphosphatase NP_239974.1 148274 D 107806 CDS NP_239975.1 15616763 1109587 complement(149125..149610) 1 NC_002528.1 dihydrofolate reductase 149610 folA 1109587 folA Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydrofolate reductase NP_239975.1 149125 R 107806 CDS NP_239976.1 15616764 1109588 complement(149700..152939) 1 NC_002528.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 152939 carB 1109588 carB Buchnera aphidicola str. APS (Acyrthosiphon pisum) carbamoyl phosphate synthase large subunit NP_239976.1 149700 R 107806 CDS NP_239977.1 15616765 1109589 complement(152953..154116) 1 NC_002528.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 154116 carA 1109589 carA Buchnera aphidicola str. APS (Acyrthosiphon pisum) carbamoyl phosphate synthase small subunit NP_239977.1 152953 R 107806 CDS NP_239978.1 15616766 1109590 complement(154326..155135) 1 NC_002528.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 155135 dapB 1109590 dapB Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydrodipicolinate reductase NP_239978.1 154326 R 107806 CDS NP_239979.1 15616767 1109591 complement(155139..156098) 1 NC_002528.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 156098 ispH 1109591 ispH Buchnera aphidicola str. APS (Acyrthosiphon pisum) 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_239979.1 155139 R 107806 CDS NP_239980.1 15616768 1109592 complement(156163..156645) 1 NC_002528.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 156645 lspA 1109592 lspA Buchnera aphidicola str. APS (Acyrthosiphon pisum) lipoprotein signal peptidase NP_239980.1 156163 R 107806 CDS NP_239981.1 15616769 1109593 complement(156645..159467) 1 NC_002528.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase 159467 ileS 1109593 ileS Buchnera aphidicola str. APS (Acyrthosiphon pisum) isoleucyl-tRNA synthetase NP_239981.1 156645 R 107806 CDS NP_239982.1 15616770 1109594 complement(159484..160425) 1 NC_002528.1 riboflavin kinase; FMN adenylyltransferase 160425 ribF 1109594 ribF Buchnera aphidicola str. APS (Acyrthosiphon pisum) FMN adenylyltransferase NP_239982.1 159484 R 107806 CDS NP_239983.1 15616771 1109595 160640..160909 1 NC_002528.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 160909 rpsT 1109595 rpsT Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S20 NP_239983.1 160640 D 107806 CDS NP_239984.1 15616772 1109596 complement(160960..162093) 1 NC_002528.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; molecular chaperone DnaJ 162093 dnaJ 1109596 dnaJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) molecular chaperone DnaJ NP_239984.1 160960 R 107806 CDS NP_239985.1 15616773 1109597 complement(162206..164119) 1 NC_002528.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 164119 dnaK 1109597 dnaK Buchnera aphidicola str. APS (Acyrthosiphon pisum) molecular chaperone DnaK NP_239985.1 162206 R 107806 CDS NP_239986.1 15616774 1109598 164454..164858 1 NC_002528.1 NADH dehydrogenase I subunit A 164858 nuoA 1109598 nuoA Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit A NP_239986.1 164454 D 107806 CDS NP_239987.1 15616775 1109599 164892..165566 1 NC_002528.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 165566 nuoB 1109599 nuoB Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase subunit B NP_239987.1 164892 D 107806 CDS NP_239988.1 15616776 1109600 165657..167459 1 NC_002528.1 NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms; bifunctional NADH:ubiquinone oxidoreductase subunit C/D 167459 nuoCD 1109600 nuoCD Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional NADH:ubiquinone oxidoreductase subunit C/D NP_239988.1 165657 D 107806 CDS NP_239989.1 15616777 1109601 167482..167970 1 NC_002528.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 167970 nuoE 1109601 nuoE Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase subunit E NP_239989.1 167482 D 107806 CDS NP_239990.1 15616778 1109602 167967..169301 1 NC_002528.1 NADH dehydrogenase I subunit F 169301 nuoF 1109602 nuoF Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit F NP_239990.1 167967 D 107806 CDS NP_239991.1 15616779 1109603 169395..172115 1 NC_002528.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 172115 nuoG 1109603 nuoG Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase subunit G NP_239991.1 169395 D 107806 CDS NP_239992.1 15616780 1109604 172127..173095 1 NC_002528.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 173095 nuoH 1109604 nuoH Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase subunit H NP_239992.1 172127 D 107806 CDS NP_239993.1 15616781 1109605 173120..173662 1 NC_002528.1 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 173662 nuoI 1109605 nuoI Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase subunit I NP_239993.1 173120 D 107806 CDS NP_239994.1 15616782 1109606 173672..174184 1 NC_002528.1 NADH dehydrogenase I subunit J 174184 nuoJ 1109606 nuoJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit J NP_239994.1 173672 D 107806 CDS NP_239995.1 15616783 1109607 174215..174517 1 NC_002528.1 NADH dehydrogenase I subunit K 174517 nuoK 1109607 nuoK Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit K NP_239995.1 174215 D 107806 CDS NP_239996.1 15616784 1109608 174514..176358 1 NC_002528.1 NADH dehydrogenase I subunit L 176358 nuoL 1109608 nuoL Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit L NP_239996.1 174514 D 107806 CDS NP_239997.1 15616785 1109609 176455..177972 1 NC_002528.1 NADH dehydrogenase I subunit M 177972 nuoM 1109609 nuoM Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit M NP_239997.1 176455 D 107806 CDS NP_239998.1 15616786 1109610 178030..179439 1 NC_002528.1 NADH dehydrogenase I subunit N 179439 nuoN 1109610 nuoN Buchnera aphidicola str. APS (Acyrthosiphon pisum) NADH dehydrogenase I subunit N NP_239998.1 178030 D 107806 CDS NP_239999.1 15616787 1109611 180565..181800 1 NC_002528.1 folylpolyglutamate synthase; dihydrofolate synthase 181800 folC 1109611 folC Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydrofolate synthase NP_239999.1 180565 D 107806 CDS NP_240000.2 28952044 1109612 complement(182379..183326) 1 NC_002528.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 183326 prsA 1109612 prsA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribose-phosphate pyrophosphokinase NP_240000.2 182379 R 107806 CDS NP_240001.1 15616789 1109613 complement(183446..184330) 1 NC_002528.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 184330 ipk 1109613 ipk Buchnera aphidicola str. APS (Acyrthosiphon pisum) 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase NP_240001.1 183446 R 107806 CDS NP_240002.1 15616790 1109614 184538..185623 1 NC_002528.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 185623 prfA 1109614 prfA Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptide chain release factor 1 NP_240002.1 184538 D 107806 CDS NP_240003.1 15616791 1109615 185620..186453 1 NC_002528.1 HemK protein 186453 hemK 1109615 hemK Buchnera aphidicola str. APS (Acyrthosiphon pisum) HemK protein NP_240003.1 185620 D 107806 CDS NP_240004.1 15616792 1109616 186613..187422 1 NC_002528.1 putative transcriptional regulator 187422 ychA 1109616 ychA Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative transcriptional regulator NP_240004.1 186613 D 107806 CDS NP_240005.1 15616793 1109617 complement(187430..188236) 1 NC_002528.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase 188236 nadE 1109617 nadE Buchnera aphidicola str. APS (Acyrthosiphon pisum) NAD synthetase NP_240005.1 187430 R 107806 CDS NP_240006.1 15616794 1109618 188320..189537 1 NC_002528.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 189537 ackA 1109618 ackA Buchnera aphidicola str. APS (Acyrthosiphon pisum) acetate kinase NP_240006.1 188320 D 107806 CDS NP_240007.1 15616795 1109619 189582..191708 1 NC_002528.1 phosphate acetyltransferase 191708 pta 1109619 pta Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphate acetyltransferase NP_240007.1 189582 D 107806 CDS NP_240008.1 15616796 1109620 complement(191740..192003) 1 NC_002528.1 hypothetical protein 192003 yfaE 1109620 yfaE Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240008.1 191740 R 107806 CDS NP_240009.1 15616797 1109621 complement(192006..193136) 1 NC_002528.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA; ribonucleotide-diphosphate reductase subunit beta 193136 nrdB 1109621 nrdB Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonucleotide-diphosphate reductase subunit beta NP_240009.1 192006 R 107806 CDS NP_240010.1 15616798 1109622 complement(193204..195489) 1 NC_002528.1 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 195489 nrdA 1109622 nrdA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonucleotide-diphosphate reductase subunit alpha NP_240010.1 193204 R 107806 CDS NP_240011.1 15616799 1109623 complement(195562..198054) 1 NC_002528.1 DNA gyrase subunit A 198054 gyrA 1109623 gyrA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA gyrase subunit A NP_240011.1 195562 R 107806 CDS NP_240012.1 15616800 1109624 198321..199037 1 NC_002528.1 hypothetical protein 199037 yba2 1109624 yba2 Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240012.1 198321 D 107806 CDS NP_240013.1 15616801 1109625 complement(199160..199753) 1 NC_002528.1 alkyl hydroperoxide reductase 199753 ahpC 1109625 ahpC Buchnera aphidicola str. APS (Acyrthosiphon pisum) alkyl hydroperoxide reductase NP_240013.1 199160 R 107806 CDS NP_240014.1 15616802 1109626 199831..200493 1 NC_002528.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 200493 ung 1109626 ung Buchnera aphidicola str. APS (Acyrthosiphon pisum) uracil-DNA glycosylase NP_240014.1 199831 D 107806 CDS NP_240015.1 15616803 1109627 complement(200569..201135) 1 NC_002528.1 heat shock protein GrpE 201135 grpE 1109627 grpE Buchnera aphidicola str. APS (Acyrthosiphon pisum) heat shock protein GrpE NP_240015.1 200569 R 107806 CDS NP_240016.1 15616804 1109628 201252..202130 1 NC_002528.1 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 202130 ppnK 1109628 ppnK Buchnera aphidicola str. APS (Acyrthosiphon pisum) inorganic polyphosphate/ATP-NAD kinase NP_240016.1 201252 D 107806 CDS NP_240017.1 15616805 1109629 202263..202571 1 NC_002528.1 small protein A 202571 smpA 1109629 smpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) small protein A NP_240017.1 202263 D 107806 CDS NP_240018.1 15616806 1109630 203108..203434 1 NC_002528.1 hypothetical protein 203434 ydhD 1109630 ydhD Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240018.1 203108 D 107806 CDS NP_240019.1 15616807 1109631 complement(203578..204243) 1 NC_002528.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A); ribonuclease T 204243 rnt 1109631 rnt Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonuclease T NP_240019.1 203578 R 107806 CDS NP_240020.1 15616808 1109632 204463..205074 1 NC_002528.1 superoxide dismutase 205074 sodA 1109632 sodA Buchnera aphidicola str. APS (Acyrthosiphon pisum) superoxide dismutase NP_240020.1 204463 D 107806 CDS NP_240021.1 15616809 1109633 205262..205795 1 NC_002528.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 205795 pth 1109633 pth Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptidyl-tRNA hydrolase NP_240021.1 205262 D 107806 CDS NP_240022.1 15616810 1109634 205836..206924 1 NC_002528.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 206924 ychF 1109634 ychF Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP-dependent nucleic acid-binding protein EngD NP_240022.1 205836 D 107806 CDS NP_240023.1 15616811 1109635 complement(207000..208289) 1 NC_002528.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 208289 thrC 1109635 thrC Buchnera aphidicola str. APS (Acyrthosiphon pisum) threonine synthase NP_240023.1 207000 R 107806 CDS NP_240024.1 15616812 1109636 complement(208296..209225) 1 NC_002528.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 209225 thrB 1109636 thrB Buchnera aphidicola str. APS (Acyrthosiphon pisum) homoserine kinase NP_240024.1 208296 R 107806 CDS NP_240025.1 15616813 1109637 complement(209246..211696) 1 NC_002528.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; bifunctional aspartokinase I/homoserine dehydrogenase I 211696 thrA 1109637 thrA Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional aspartokinase I/homoserine dehydrogenase I NP_240025.1 209246 R 107806 CDS NP_240026.1 15616814 1109638 212355..212855 1 NC_002528.1 hypoxanthine phosphoribosyltransferase 212855 hpt 1109638 hpt Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypoxanthine phosphoribosyltransferase NP_240026.1 212355 D 107806 CDS NP_240027.1 15616815 1109639 complement(212899..213756) 1 NC_002528.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantoate--beta-alanine ligase 213756 panC 1109639 panC Buchnera aphidicola str. APS (Acyrthosiphon pisum) pantoate--beta-alanine ligase NP_240027.1 212899 R 107806 CDS NP_240028.1 15616816 1109640 complement(213771..214562) 1 NC_002528.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 214562 panB 1109640 panB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_240028.1 213771 R 107806 CDS NP_240029.1 15616817 1109641 complement(214678..215133) 1 NC_002528.1 DnaK suppressor protein 215133 dksA 1109641 dksA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DnaK suppressor protein NP_240029.1 214678 R 107806 CDS NP_240030.1 15616818 1109642 215390..216190 1 NC_002528.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 216190 truA 1109642 truA Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA pseudouridine synthase A NP_240030.1 215390 D 107806 CDS NP_240031.1 15616819 1109643 216262..218544 1 NC_002528.1 bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; penicillin-binding protein 1b 218544 mrcB 1109643 mrcB Buchnera aphidicola str. APS (Acyrthosiphon pisum) penicillin-binding protein 1b NP_240031.1 216262 D 107806 CDS NP_240032.1 15616820 1109644 218774..221401 1 NC_002528.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 221401 secA 1109644 secA Buchnera aphidicola str. APS (Acyrthosiphon pisum) preprotein translocase subunit SecA NP_240032.1 218774 D 107806 CDS NP_240033.1 15616821 1109645 221477..221851 1 NC_002528.1 mutator MutT protein 221851 mutT 1109645 mutT Buchnera aphidicola str. APS (Acyrthosiphon pisum) mutator MutT protein NP_240033.1 221477 D 107806 CDS NP_240034.1 15616822 1109646 complement(221834..222487) 1 NC_002528.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 222487 coaE 1109646 coaE Buchnera aphidicola str. APS (Acyrthosiphon pisum) dephospho-CoA kinase NP_240034.1 221834 R 107806 CDS NP_240035.1 15616823 1109647 222543..223592 1 NC_002528.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate; guanosine 5'-monophosphate oxidoreductase 223592 guaC 1109647 guaC Buchnera aphidicola str. APS (Acyrthosiphon pisum) guanosine 5'-monophosphate oxidoreductase NP_240035.1 222543 D 107806 CDS NP_240036.1 15616824 1109648 223819..226482 1 NC_002528.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; pyruvate dehydrogenase subunit E1 226482 aceE 1109648 aceE Buchnera aphidicola str. APS (Acyrthosiphon pisum) pyruvate dehydrogenase subunit E1 NP_240036.1 223819 D 107806 CDS NP_240037.2 28952045 1109649 226486..227703 1 NC_002528.1 branched-chain alpha-keto acid dehydrogenase subunit E2 227703 aceF 1109649 aceF Buchnera aphidicola str. APS (Acyrthosiphon pisum) branched-chain alpha-keto acid dehydrogenase subunit E2 NP_240037.2 226486 D 107806 CDS NP_240038.1 15616826 1109650 227748..229169 1 NC_002528.1 dihydrolipoamide dehydrogenase 229169 lpdA 1109650 lpdA Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydrolipoamide dehydrogenase NP_240038.1 227748 D 107806 CDS NP_240039.1 15616827 1109651 complement(229342..230139) 1 NC_002528.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase 230139 speD 1109651 speD Buchnera aphidicola str. APS (Acyrthosiphon pisum) S-adenosylmethionine decarboxylase NP_240039.1 229342 R 107806 CDS NP_240040.1 15616828 1109652 complement(230158..231018) 1 NC_002528.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 231018 speE 1109652 speE Buchnera aphidicola str. APS (Acyrthosiphon pisum) spermidine synthase NP_240040.1 230158 R 107806 CDS NP_240041.1 15616829 1109653 complement(231294..231992) 1 NC_002528.1 S-adenosylhomocysteine nucleosidase; 5'-methylthioadenosine nucleosidase 231992 pfs 1109653 pfs Buchnera aphidicola str. APS (Acyrthosiphon pisum) 5'-methylthioadenosine nucleosidase NP_240041.1 231294 R 107806 CDS NP_240042.1 15616830 1109654 complement(232056..232400) 1 NC_002528.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors; iron-sulfur cluster insertion protein ErpA 232400 yadR 1109654 yadR Buchnera aphidicola str. APS (Acyrthosiphon pisum) iron-sulfur cluster insertion protein ErpA NP_240042.1 232056 R 107806 CDS NP_240043.1 15616831 1109655 complement(232634..233788) 1 NC_002528.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 233788 ftsZ 1109655 ftsZ Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsZ NP_240043.1 232634 R 107806 CDS NP_240044.1 15616832 1109656 complement(233846..235102) 1 NC_002528.1 cell division protein FtsA 235102 ftsA 1109656 ftsA Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsA NP_240044.1 233846 R 107806 CDS NP_240045.1 15616833 1109658 complement(236217..237671) 1 NC_002528.1 UDP-N-acetylmuramate-alanine ligase 237671 murC 1109658 murC Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylmuramate-alanine ligase NP_240045.1 236217 R 107806 CDS NP_240046.1 15616834 1109659 complement(237714..238778) 1 NC_002528.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 238778 murG 1109659 murG Buchnera aphidicola str. APS (Acyrthosiphon pisum) undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase NP_240046.1 237714 R 107806 CDS NP_240047.1 15616835 1109660 complement(238775..239974) 1 NC_002528.1 cell division protein FtsW 239974 ftsW 1109660 ftsW Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsW NP_240047.1 238775 R 107806 CDS NP_240048.1 15616836 1109661 complement(239971..241293) 1 NC_002528.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 241293 murD 1109661 murD Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase NP_240048.1 239971 R 107806 CDS NP_240049.1 15616837 1109662 complement(241293..242366) 1 NC_002528.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 242366 mraY 1109662 mraY Buchnera aphidicola str. APS (Acyrthosiphon pisum) phospho-N-acetylmuramoyl-pentapeptide- transferase NP_240049.1 241293 R 107806 CDS NP_240050.1 15616838 1109663 complement(242360..243727) 1 NC_002528.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 243727 murF 1109663 murF Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase NP_240050.1 242360 R 107806 CDS NP_240051.1 15616839 1109664 complement(243724..245217) 1 NC_002528.1 UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase 245217 murE 1109664 murE Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase NP_240051.1 243724 R 107806 CDS NP_240052.1 15616840 1109665 complement(245218..246957) 1 NC_002528.1 cell division protein FtsI 246957 ftsI 1109665 ftsI Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsI NP_240052.1 245218 R 107806 CDS NP_240053.1 15617194 1109666 complement(join(247022..247093,247093..247275)) 1 NC_002528.1 cell division protein 247275 ftsL 1109666 ftsL Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein NP_240053.1 247022 R 107806 CDS NP_240054.1 15616841 1109667 complement(247278..248216) 1 NC_002528.1 S-adenosyl-methyltransferase MraW 248216 mraW 1109667 mraW Buchnera aphidicola str. APS (Acyrthosiphon pisum) S-adenosyl-methyltransferase MraW NP_240054.1 247278 R 107806 CDS NP_240055.1 15616842 1109668 complement(248338..248814) 1 NC_002528.1 acetolactate synthase small subunit 248814 ilvH 1109668 ilvH Buchnera aphidicola str. APS (Acyrthosiphon pisum) acetolactate synthase small subunit NP_240055.1 248338 R 107806 CDS NP_240056.1 15616843 1109669 complement(248819..250534) 1 NC_002528.1 acetolactate synthase large subunit 250534 ilvI 1109669 ilvI Buchnera aphidicola str. APS (Acyrthosiphon pisum) acetolactate synthase large subunit NP_240056.1 248819 R 107806 CDS NP_240057.1 15616844 1109671 252152..253588 1 NC_002528.1 protease Do; required at high temperature; degrades damaged proteins; serine endoprotease 253588 htrA 1109671 htrA Buchnera aphidicola str. APS (Acyrthosiphon pisum) serine endoprotease NP_240057.1 252152 D 107806 CDS NP_240058.1 15616845 1109672 complement(253632..254456) 1 NC_002528.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 254456 dapD 1109672 dapD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase NP_240058.1 253632 R 107806 CDS NP_240059.1 15616846 1109673 complement(254517..255311) 1 NC_002528.1 methionine aminopeptidase 255311 map 1109673 map Buchnera aphidicola str. APS (Acyrthosiphon pisum) methionine aminopeptidase NP_240059.1 254517 R 107806 CDS NP_240060.1 15616847 1109674 255574..256308 1 NC_002528.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 256308 rpsB 1109674 rpsB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S2 NP_240060.1 255574 D 107806 CDS NP_240061.1 15616848 1109675 256385..257191 1 NC_002528.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 257191 tsf 1109675 tsf Buchnera aphidicola str. APS (Acyrthosiphon pisum) elongation factor Ts NP_240061.1 256385 D 107806 CDS NP_240062.1 15616849 1109676 257242..257970 1 NC_002528.1 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 257970 pyrH 1109676 pyrH Buchnera aphidicola str. APS (Acyrthosiphon pisum) uridylate kinase NP_240062.1 257242 D 107806 CDS NP_240063.1 15616850 1109677 258051..258608 1 NC_002528.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 258608 frr 1109677 frr Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribosome recycling factor NP_240063.1 258051 D 107806 CDS NP_240064.1 15616851 1109678 258691..259887 1 NC_002528.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 259887 dxr 1109678 dxr Buchnera aphidicola str. APS (Acyrthosiphon pisum) 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_240064.1 258691 D 107806 CDS NP_240065.1 15616852 1109679 259980..260735 1 NC_002528.1 undecaprenyl pyrophosphate synthetase 260735 uppS 1109679 uppS Buchnera aphidicola str. APS (Acyrthosiphon pisum) undecaprenyl pyrophosphate synthetase NP_240065.1 259980 D 107806 CDS NP_240066.1 15616853 1109680 260969..262822 1 NC_002528.1 hypothetical protein 262822 yaeT 1109680 yaeT Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240066.1 260969 D 107806 CDS NP_240067.1 15616854 1109681 262859..266344 1 NC_002528.1 DNA polymerase III subunit alpha 266344 dnaE 1109681 dnaE Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III subunit alpha NP_240067.1 262859 D 107806 CDS NP_240068.1 15616855 1109682 complement(266472..268190) 1 NC_002528.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 268190 proS 1109682 proS Buchnera aphidicola str. APS (Acyrthosiphon pisum) prolyl-tRNA synthetase NP_240068.1 266472 R 107806 CDS NP_240069.1 15616856 1109683 268530..269681 1 NC_002528.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthesis protein FlhB 269681 flhB 1109683 flhB Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar biosynthesis protein FlhB NP_240069.1 268530 D 107806 CDS NP_240070.2 28952046 1109684 269674..271764 1 NC_002528.1 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 271764 flhA 1109684 flhA Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar biosynthesis protein FlhA NP_240070.2 269674 D 107806 CDS NP_240071.1 15616858 1109685 complement(271888..273612) 1 NC_002528.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 273612 argS 1109685 argS Buchnera aphidicola str. APS (Acyrthosiphon pisum) arginyl-tRNA synthetase NP_240071.1 271888 R 107806 CDS NP_240072.1 15616859 1109686 complement(275795..276550) 1 NC_002528.1 hydroxyacylglutathione hydrolase 276550 gloB 1109686 gloB Buchnera aphidicola str. APS (Acyrthosiphon pisum) hydroxyacylglutathione hydrolase NP_240072.1 275795 R 107806 CDS NP_240073.1 15616860 1109688 277113..277826 1 NC_002528.1 DNA polymerase III subunit epsilon 277826 dnaQ 1109688 dnaQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III subunit epsilon NP_240073.1 277113 D 107806 CDS NP_240074.1 15616861 1109689 278052..278633 1 NC_002528.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate; phosphoheptose isomerase 278633 gmhA 1109689 gmhA Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoheptose isomerase NP_240074.1 278052 D 107806 CDS NP_240075.2 28952047 1109690 278740..279216 1 NC_002528.1 catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively; xanthine-guanine phosphoribosyltransferase 279216 gpt 1109690 gpt Buchnera aphidicola str. APS (Acyrthosiphon pisum) xanthine-guanine phosphoribosyltransferase NP_240075.2 278740 D 107806 CDS NP_240076.1 15616863 1109691 279317..279901 1 NC_002528.1 heat shock protein GrpE 279901 grpE1 1109691 grpE1 Buchnera aphidicola str. APS (Acyrthosiphon pisum) heat shock protein GrpE NP_240076.1 279317 D 107806 CDS NP_240077.1 15616864 1109692 complement(279980..280279) 1 NC_002528.1 hypothetical protein 280279 yfjF 1109692 yfjF Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240077.1 279980 R 107806 CDS NP_240078.1 15616865 1109693 280373..280861 1 NC_002528.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 280861 smpB 1109693 smpB Buchnera aphidicola str. APS (Acyrthosiphon pisum) SsrA-binding protein NP_240078.1 280373 D 107806 CDS NP_240079.1 15616866 1109694 280870..281355 1 NC_002528.1 hypothetical protein 281355 yfhC 1109694 yfhC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240079.1 280870 D 107806 CDS NP_240080.1 15616867 1109695 complement(281356..281736) 1 NC_002528.1 holo-ACP synthase 281736 acpS 1109695 acpS Buchnera aphidicola str. APS (Acyrthosiphon pisum) holo-ACP synthase NP_240080.1 281356 R 107806 CDS NP_240081.1 15616868 1109696 complement(281861..282712) 1 NC_002528.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 282712 era 1109696 era Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP-binding protein Era NP_240081.1 281861 R 107806 CDS NP_240082.1 15616869 1109697 complement(282709..283389) 1 NC_002528.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 283389 rnc 1109697 rnc Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonuclease III NP_240082.1 282709 R 107806 CDS NP_240083.1 15616870 1109698 complement(283520..284464) 1 NC_002528.1 signal peptidase I 284464 lepB 1109698 lepB Buchnera aphidicola str. APS (Acyrthosiphon pisum) signal peptidase I NP_240083.1 283520 R 107806 CDS NP_240084.1 15616871 1109699 complement(284480..286312) 1 NC_002528.1 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 286312 lepA 1109699 lepA Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP-binding protein LepA NP_240084.1 284480 R 107806 CDS NP_240085.2 28952048 1109700 286508..287614 1 NC_002528.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 287614 mnmA 1109700 mnmA Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA-specific 2-thiouridylase MnmA NP_240085.2 286508 D 107806 CDS NP_240086.1 15616873 1109701 287650..288285 1 NC_002528.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis; hypothetical protein 288285 ycfC 1109701 ycfC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240086.1 287650 D 107806 CDS NP_240087.1 15616874 1109702 288324..289694 1 NC_002528.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 289694 purB 1109702 purB Buchnera aphidicola str. APS (Acyrthosiphon pisum) adenylosuccinate lyase NP_240087.1 288324 D 107806 CDS NP_240088.1 15616875 1109703 289718..290383 1 NC_002528.1 membrane-bound lytic murein transglycosylase E 290383 mltE 1109703 mltE Buchnera aphidicola str. APS (Acyrthosiphon pisum) membrane-bound lytic murein transglycosylase E NP_240088.1 289718 D 107806 CDS NP_240089.1 15616876 1109704 290497..291279 1 NC_002528.1 enoyl-ACP reductase 291279 fabI 1109704 fabI Buchnera aphidicola str. APS (Acyrthosiphon pisum) enoyl-ACP reductase NP_240089.1 290497 D 107806 CDS NP_240090.1 15616877 1109705 291466..293415 1 NC_002528.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction; exoribonuclease II 293415 rnb 1109705 rnb Buchnera aphidicola str. APS (Acyrthosiphon pisum) exoribonuclease II NP_240090.1 291466 D 107806 CDS NP_240091.1 15616878 1109706 293524..294171 1 NC_002528.1 hypothetical protein 294171 ychE 1109706 ychE Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240091.1 293524 D 107806 CDS NP_240092.1 15616879 1109707 294209..294844 1 NC_002528.1 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 294844 lipB 1109707 lipB Buchnera aphidicola str. APS (Acyrthosiphon pisum) lipoyltransferase NP_240092.1 294209 D 107806 CDS NP_240093.1 15616880 1109708 294963..295934 1 NC_002528.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 295934 lipA 1109708 lipA Buchnera aphidicola str. APS (Acyrthosiphon pisum) lipoyl synthase NP_240093.1 294963 D 107806 CDS NP_240094.1 15616881 1109709 296039..296749 1 NC_002528.1 orotidine 5'-phosphate decarboxylase 296749 pyrF 1109709 pyrF Buchnera aphidicola str. APS (Acyrthosiphon pisum) orotidine 5'-phosphate decarboxylase NP_240094.1 296039 D 107806 CDS NP_240095.1 15616882 1109710 296797..297381 1 NC_002528.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate; GTP cyclohydrolase II 297381 ribA 1109710 ribA Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP cyclohydrolase II NP_240095.1 296797 D 107806 CDS NP_240096.1 15616883 1109711 complement(297485..297892) 1 NC_002528.1 DNA-binding protein H-NS 297892 hns 1109711 hns Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA-binding protein H-NS NP_240096.1 297485 R 107806 CDS NP_240097.1 15616884 1109712 complement(298238..299698) 1 NC_002528.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol); cardiolipin synthetase 299698 cls 1109712 cls Buchnera aphidicola str. APS (Acyrthosiphon pisum) cardiolipin synthetase NP_240097.1 298238 R 107806 CDS NP_240098.1 15616885 1109713 complement(300079..300486) 1 NC_002528.1 hypothetical protein 300486 yciA 1109713 yciA Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240098.1 300079 R 107806 CDS NP_240099.1 15616886 1109714 complement(300523..301056) 1 NC_002528.1 Involved in cell division; probably involved in intracellular septation; intracellular septation protein A 301056 yciB 1109714 yciB Buchnera aphidicola str. APS (Acyrthosiphon pisum) intracellular septation protein A NP_240099.1 300523 R 107806 CDS NP_240100.1 15616887 1109715 complement(301084..301827) 1 NC_002528.1 hypothetical protein 301827 yciC 1109715 yciC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240100.1 301084 R 107806 CDS NP_240101.1 15616888 1109716 complement(301932..302741) 1 NC_002528.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha 302741 trpA 1109716 trpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) tryptophan synthase subunit alpha NP_240101.1 301932 R 107806 CDS NP_240102.1 15616889 1109717 complement(302760..303926) 1 NC_002528.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta 303926 trpB 1109717 trpB Buchnera aphidicola str. APS (Acyrthosiphon pisum) tryptophan synthase subunit beta NP_240102.1 302760 R 107806 CDS NP_240103.1 15616890 1109718 complement(303964..305325) 1 NC_002528.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate; bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase 305325 trpC 1109718 trpC Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase NP_240103.1 303964 R 107806 CDS NP_240104.1 15616891 1109719 complement(305306..306334) 1 NC_002528.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 306334 trpD 1109719 trpD Buchnera aphidicola str. APS (Acyrthosiphon pisum) anthranilate phosphoribosyltransferase NP_240104.1 305306 R 107806 CDS NP_240105.1 15616892 1109980 306569..307492 1 NC_002528.1 hypothetical protein 307492 yedA 1109980 yedA Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240105.1 306569 D 107806 CDS NP_240106.1 15616893 1109981 307521..308273 1 NC_002528.1 hypothetical protein 308273 yciL 1109981 yciL Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240106.1 307521 D 107806 CDS NP_240107.2 28952049 1109982 308348..309358 1 NC_002528.1 SohB; periplasmic protein; member of the peptidase S49 family; putative periplasmic protease 309358 sohB 1109982 sohB Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative periplasmic protease NP_240107.2 308348 D 107806 CDS NP_240108.1 15616895 1109983 309445..312030 1 NC_002528.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 312030 topA 1109983 topA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA topoisomerase I NP_240108.1 309445 D 107806 CDS NP_240109.1 15616896 1109984 complement(312083..312883) 1 NC_002528.1 extragenic suppressor protein SuhB 312883 suhB 1109984 suhB Buchnera aphidicola str. APS (Acyrthosiphon pisum) extragenic suppressor protein SuhB NP_240109.1 312083 R 107806 CDS NP_240110.1 15616897 1109985 313130..314221 1 NC_002528.1 hypothetical protein 314221 yfgB 1109985 yfgB Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240110.1 313130 D 107806 CDS NP_240111.1 15616898 1109986 314272..315378 1 NC_002528.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 315378 ispG 1109986 ispG Buchnera aphidicola str. APS (Acyrthosiphon pisum) 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_240111.1 314272 D 107806 CDS NP_240112.1 15616899 1109987 315404..316675 1 NC_002528.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 316675 hisS 1109987 hisS Buchnera aphidicola str. APS (Acyrthosiphon pisum) histidyl-tRNA synthetase NP_240112.1 315404 D 107806 CDS NP_240113.1 15616900 1109988 316735..317988 1 NC_002528.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 317988 glyA 1109988 glyA Buchnera aphidicola str. APS (Acyrthosiphon pisum) serine hydroxymethyltransferase NP_240113.1 316735 D 107806 CDS NP_240114.1 15616901 1109989 complement(318076..318750) 1 NC_002528.1 dethiobiotin synthetase 318750 bioD 1109989 bioD Buchnera aphidicola str. APS (Acyrthosiphon pisum) dethiobiotin synthetase NP_240114.1 318076 R 107806 CDS NP_240115.1 15616902 1109990 complement(319115..320146) 1 NC_002528.1 biotin synthetase 320146 bioB 1109990 bioB Buchnera aphidicola str. APS (Acyrthosiphon pisum) biotin synthetase NP_240115.1 319115 R 107806 CDS NP_240116.1 15616903 1109991 320225..321511 1 NC_002528.1 adenosylmethionine-8-amino-7-oxononanoate aminotransferase 321511 bioA 1109991 bioA Buchnera aphidicola str. APS (Acyrthosiphon pisum) adenosylmethionine-8-amino-7-oxononanoate aminotransferase NP_240116.1 320225 D 107806 CDS NP_240117.1 15616904 1109992 complement(321520..322524) 1 NC_002528.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate; 6-phosphogluconolactonase 322524 ybhE 1109992 ybhE Buchnera aphidicola str. APS (Acyrthosiphon pisum) 6-phosphogluconolactonase NP_240117.1 321520 R 107806 CDS NP_240118.1 15616905 1109993 complement(322648..325086) 1 NC_002528.1 transcription-repair coupling factor 325086 mfd 1109993 mfd Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription-repair coupling factor NP_240118.1 322648 R 107806 CDS NP_240119.1 15616906 1109994 325561..326760 1 NC_002528.1 hypothetical protein 326760 ycfU 1109994 ycfU Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240119.1 325561 D 107806 CDS NP_240120.1 15616907 1109995 326753..327439 1 NC_002528.1 ABC transporter ATP-binding protein 327439 ycfV 1109995 ycfV Buchnera aphidicola str. APS (Acyrthosiphon pisum) ABC transporter ATP-binding protein NP_240120.1 326753 D 107806 CDS NP_240121.1 15616908 1109997 328764..329774 1 NC_002528.1 glyceraldehyde 3-phosphate dehydrogenase A 329774 gapA 1109997 gapA Buchnera aphidicola str. APS (Acyrthosiphon pisum) glyceraldehyde 3-phosphate dehydrogenase A NP_240121.1 328764 D 107806 CDS NP_240122.1 15616909 1109998 complement(330105..330620) 1 NC_002528.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin FldA 330620 fldA 1109998 fldA Buchnera aphidicola str. APS (Acyrthosiphon pisum) flavodoxin FldA NP_240122.1 330105 R 107806 CDS NP_240123.1 15616910 1109999 330827..332278 1 NC_002528.1 deoxyribodipyrimidine photolyase 332278 phrB 1109999 phrB Buchnera aphidicola str. APS (Acyrthosiphon pisum) deoxyribodipyrimidine photolyase NP_240123.1 330827 D 107806 CDS NP_240124.1 15616911 1110000 332275..333018 1 NC_002528.1 hypothetical protein 333018 ybgI 1110000 ybgI Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240124.1 332275 D 107806 CDS NP_240125.1 15616912 1110001 333143..335872 1 NC_002528.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 335872 sucA 1110001 sucA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2-oxoglutarate dehydrogenase E1 NP_240125.1 333143 D 107806 CDS NP_240126.1 15616913 1110002 335888..337150 1 NC_002528.1 dihydrolipoamide succinyltransferase; 2-oxoglutarate dehydrogenase E2 component 337150 sucB 1110002 sucB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2-oxoglutarate dehydrogenase E2 component NP_240126.1 335888 D 107806 CDS NP_240127.1 15616914 1110003 337248..337943 1 NC_002528.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase 337943 gpmA 1110003 gpmA Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoglyceromutase NP_240127.1 337248 D 107806 CDS NP_240128.1 15616915 1110004 338127..339089 1 NC_002528.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 339089 pfkA 1110004 pfkA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 6-phosphofructokinase NP_240128.1 338127 D 107806 CDS NP_240129.1 15616916 1110005 339155..339946 1 NC_002528.1 glycerol uptake facilitator protein 339946 glpF 1110005 glpF Buchnera aphidicola str. APS (Acyrthosiphon pisum) glycerol uptake facilitator protein NP_240129.1 339155 D 107806 CDS NP_240130.1 15616917 1110006 complement(339955..340722) 1 NC_002528.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 340722 tpiA 1110006 tpiA Buchnera aphidicola str. APS (Acyrthosiphon pisum) triosephosphate isomerase NP_240130.1 339955 R 107806 CDS NP_240131.1 15616918 1110007 complement(340821..341105) 1 NC_002528.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control; integration host factor subunit beta 341105 ihfB 1110007 ihfB Buchnera aphidicola str. APS (Acyrthosiphon pisum) integration host factor subunit beta NP_240131.1 340821 R 107806 CDS NP_240132.1 15616919 1110008 complement(341201..342877) 1 NC_002528.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 342877 rpsA 1110008 rpsA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S1 NP_240132.1 341201 R 107806 CDS NP_240133.1 15616920 1110010 complement(343716..344999) 1 NC_002528.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 344999 aroA 1110010 aroA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-phosphoshikimate 1-carboxyvinyltransferase NP_240133.1 343716 R 107806 CDS NP_240134.1 15616921 1110011 complement(345066..346151) 1 NC_002528.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 346151 serC 1110011 serC Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoserine aminotransferase NP_240134.1 345066 R 107806 CDS NP_240135.1 15616922 1110012 complement(346190..347473) 1 NC_002528.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 347473 serS 1110012 serS Buchnera aphidicola str. APS (Acyrthosiphon pisum) seryl-tRNA synthetase NP_240135.1 346190 R 107806 CDS NP_240136.1 15616923 1110013 347821..348780 1 NC_002528.1 thioredoxin reductase 348780 trxB 1110013 trxB Buchnera aphidicola str. APS (Acyrthosiphon pisum) thioredoxin reductase NP_240136.1 347821 D 107806 CDS NP_240137.1 15616924 1110014 348887..349105 1 NC_002528.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 349105 infA 1110014 infA Buchnera aphidicola str. APS (Acyrthosiphon pisum) translation initiation factor IF-1 NP_240137.1 348887 D 107806 CDS NP_240138.1 15616925 1110015 349274..351034 1 NC_002528.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase 351034 aspS 1110015 aspS Buchnera aphidicola str. APS (Acyrthosiphon pisum) aspartyl-tRNA synthetase NP_240138.1 349274 D 107806 CDS NP_240139.1 15616926 1110016 complement(351045..351833) 1 NC_002528.1 high-affinity zinc uptake system membrane protein ZnuB 351833 znuB 1110016 znuB Buchnera aphidicola str. APS (Acyrthosiphon pisum) high-affinity zinc uptake system membrane protein ZnuB NP_240139.1 351045 R 107806 CDS NP_240140.1 15616927 1110017 complement(351891..352607) 1 NC_002528.1 high-affinity zinc uptake system ATP-binding protein ZnuC 352607 znuC 1110017 znuC Buchnera aphidicola str. APS (Acyrthosiphon pisum) high-affinity zinc uptake system ATP-binding protein ZnuC NP_240140.1 351891 R 107806 CDS NP_240141.1 15616928 1110018 complement(353925..355367) 1 NC_002528.1 pyruvate kinase 355367 pykA 1110018 pykA Buchnera aphidicola str. APS (Acyrthosiphon pisum) pyruvate kinase NP_240141.1 353925 R 107806 CDS NP_240142.1 15616929 1110019 355650..357125 1 NC_002528.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 357125 zwf 1110019 zwf Buchnera aphidicola str. APS (Acyrthosiphon pisum) glucose-6-phosphate 1-dehydrogenase NP_240142.1 355650 D 107806 CDS NP_240143.1 15616930 1110020 357310..358188 1 NC_002528.1 putative metalloprotease; heat shock protein HtpX 358188 htpX 1110020 htpX Buchnera aphidicola str. APS (Acyrthosiphon pisum) heat shock protein HtpX NP_240143.1 357310 D 107806 CDS NP_240144.1 15616931 1110021 358537..358746 1 NC_002528.1 cold shock-like protein CspC 358746 cspC 1110021 cspC Buchnera aphidicola str. APS (Acyrthosiphon pisum) cold shock-like protein CspC NP_240144.1 358537 D 107806 CDS NP_240145.1 15616932 1110022 359049..360614 1 NC_002528.1 hypothetical protein 360614 yoaE 1110022 yoaE Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240145.1 359049 D 107806 CDS NP_240146.1 15616933 1110023 360644..361309 1 NC_002528.1 hypothetical protein 361309 yeaZ 1110023 yeaZ Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240146.1 360644 D 107806 CDS NP_240147.1 15616934 1110024 complement(361455..361706) 1 NC_002528.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell; cell division topological specificity factor MinE 361706 minE 1110024 minE Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division topological specificity factor MinE NP_240147.1 361455 R 107806 CDS NP_240148.1 15616935 1110025 complement(361710..362522) 1 NC_002528.1 septum site-determining protein MinD 362522 minD 1110025 minD Buchnera aphidicola str. APS (Acyrthosiphon pisum) septum site-determining protein MinD NP_240148.1 361710 R 107806 CDS NP_240149.1 15616936 1110026 complement(362549..363262) 1 NC_002528.1 cell division inhibitor MinC 363262 minC 1110026 minC Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division inhibitor MinC NP_240149.1 362549 R 107806 CDS NP_240150.1 15616937 1110027 363663..364505 1 NC_002528.1 hypothetical protein 364505 yjjT 1110027 yjjT Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240150.1 363663 D 107806 CDS NP_240151.1 15616938 1110028 complement(365056..366105) 1 NC_002528.1 outer membrane protein OmpA 366105 ompA 1110028 ompA Buchnera aphidicola str. APS (Acyrthosiphon pisum) outer membrane protein OmpA NP_240151.1 365056 R 107806 CDS NP_240152.1 15616939 1110029 complement(366242..367777) 1 NC_002528.1 virulence factor MviN-like protein 367777 mviN 1110029 mviN Buchnera aphidicola str. APS (Acyrthosiphon pisum) virulence factor MviN-like protein NP_240152.1 366242 R 107806 CDS NP_240153.1 15616940 1110030 368052..369104 1 NC_002528.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 369104 pyrC 1110030 pyrC Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydroorotase NP_240153.1 368052 D 107806 CDS NP_240154.1 15616941 1110031 complement(369124..369531) 1 NC_002528.1 flagellar synthesis protein FlgN 369531 flgN 1110031 flgN Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar synthesis protein FlgN NP_240154.1 369124 R 107806 CDS NP_240155.1 15616942 1110032 complement(369604..370284) 1 NC_002528.1 flagella basal-body P-ring formation protein FlgA 370284 flgA 1110032 flgA Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagella basal-body P-ring formation protein FlgA NP_240155.1 369604 R 107806 CDS NP_240156.1 15616943 1110033 370621..370968 1 NC_002528.1 flagellar basal-body rod protein FlgB 370968 flgB 1110033 flgB Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal-body rod protein FlgB NP_240156.1 370621 D 107806 CDS NP_240157.1 15616944 1110034 370977..371387 1 NC_002528.1 flagellar basal body rod protein FlgC 371387 flgC 1110034 flgC Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal body rod protein FlgC NP_240157.1 370977 D 107806 CDS NP_240158.1 15616945 1110035 371399..372109 1 NC_002528.1 basal-body rod modification protein FlgD 372109 flgD 1110035 flgD Buchnera aphidicola str. APS (Acyrthosiphon pisum) basal-body rod modification protein FlgD NP_240158.1 371399 D 107806 CDS NP_240159.2 28952050 1110036 372150..373376 1 NC_002528.1 flagellar hook protein FlgE 373376 flgE 1110036 flgE Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar hook protein FlgE NP_240159.2 372150 D 107806 CDS NP_240160.2 28952051 1110037 373403..374161 1 NC_002528.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod; flagellar basal body rod protein FlgF 374161 flgF 1110037 flgF Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal body rod protein FlgF NP_240160.2 373403 D 107806 CDS NP_240161.1 15616948 1110038 374179..374961 1 NC_002528.1 makes up the distal portion of the flagellar basal body rod; flagellar basal body rod protein FlgG 374961 flgG 1110038 flgG Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal body rod protein FlgG NP_240161.1 374179 D 107806 CDS NP_240162.1 15616949 1110039 375045..375761 1 NC_002528.1 part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod; flagellar basal body L-ring protein 375761 flgH 1110039 flgH Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal body L-ring protein NP_240162.1 375045 D 107806 CDS NP_240163.1 15616950 1110040 375942..377099 1 NC_002528.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum; flagellar basal body P-ring biosynthesis protein FlgA 377099 flgI 1110040 flgI Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar basal body P-ring biosynthesis protein FlgA NP_240163.1 375942 D 107806 CDS NP_240164.1 15616951 1110041 377099..377398 1 NC_002528.1 flagellar protein FlgJ 377398 flgJ 1110041 flgJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar protein FlgJ NP_240164.1 377099 D 107806 CDS NP_240165.1 15616952 1110042 377500..379131 1 NC_002528.1 flagellar hook-associated protein 1 379131 flgK 1110042 flgK Buchnera aphidicola str. APS (Acyrthosiphon pisum) flagellar hook-associated protein 1 NP_240165.1 377500 D 107806 CDS NP_240166.1 15616953 1110043 complement(379296..382004) 1 NC_002528.1 ribonuclease E 382004 rne 1110043 rne Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribonuclease E NP_240166.1 379296 R 107806 CDS NP_240167.1 15616954 1110044 382339..383283 1 NC_002528.1 ribosomal large subunit pseudouridine synthase C 383283 rluC 1110044 rluC Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribosomal large subunit pseudouridine synthase C NP_240167.1 382339 D 107806 CDS NP_240168.1 15616955 1110045 383329..383493 1 NC_002528.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 383493 rpmF 1110045 rpmF Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L32 NP_240168.1 383329 D 107806 CDS YP_008492944.1 537727145 1110046 383914..384393 1 NC_002528.1 BU350 384393 fabD 1110046 fabD Buchnera aphidicola str. APS (Acyrthosiphon pisum) YP_008492944.1 383914 D 107806 CDS NP_240169.1 15616956 1110047 384859..385593 1 NC_002528.1 3-oxoacyl-ACP reductase 385593 fabG 1110047 fabG Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-oxoacyl-ACP reductase NP_240169.1 384859 D 107806 CDS NP_240170.1 15616957 1110048 385670..385912 1 NC_002528.1 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 385912 acpP 1110048 acpP Buchnera aphidicola str. APS (Acyrthosiphon pisum) acyl carrier protein NP_240170.1 385670 D 107806 CDS NP_240171.1 15616958 1110049 385983..386621 1 NC_002528.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 386621 tmk 1110049 tmk Buchnera aphidicola str. APS (Acyrthosiphon pisum) thymidylate kinase NP_240171.1 385983 D 107806 CDS NP_240172.1 15616959 1110050 386618..387598 1 NC_002528.1 DNA polymerase III subunit delta' 387598 holB 1110050 holB Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III subunit delta' NP_240172.1 386618 D 107806 CDS NP_240173.1 15616960 1110051 387632..388426 1 NC_002528.1 hypothetical protein 388426 ycfH 1110051 ycfH Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240173.1 387632 D 107806 CDS NP_240174.2 28952052 1110052 388523..389956 1 NC_002528.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; PTS system glucose-specific transporter subunit IIBC 389956 ptsG 1110052 ptsG Buchnera aphidicola str. APS (Acyrthosiphon pisum) PTS system glucose-specific transporter subunit IIBC NP_240174.2 388523 D 107806 CDS NP_240175.1 15616962 1110053 389976..390320 1 NC_002528.1 hypothetical protein 390320 ycfF 1110053 ycfF Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240175.1 389976 D 107806 CDS NP_240176.1 15616963 1110054 390397..390906 1 NC_002528.1 hypothetical protein 390906 ycfM 1110054 ycfM Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240176.1 390397 D 107806 CDS NP_240177.1 15616964 1110055 complement(391155..392303) 1 NC_002528.1 OmpF-like porin 392303 ompF 1110055 ompF Buchnera aphidicola str. APS (Acyrthosiphon pisum) OmpF-like porin NP_240177.1 391155 R 107806 CDS NP_240178.1 15616965 1110056 complement(392443..393843) 1 NC_002528.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase 393843 asnC 1110056 asnC Buchnera aphidicola str. APS (Acyrthosiphon pisum) asparaginyl-tRNA synthetase NP_240178.1 392443 R 107806 CDS NP_240179.1 15616966 1110057 complement(393991..395190) 1 NC_002528.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 395190 pncB 1110057 pncB Buchnera aphidicola str. APS (Acyrthosiphon pisum) nicotinate phosphoribosyltransferase NP_240179.1 393991 R 107806 CDS NP_240180.1 15616967 1110058 395612..396475 1 NC_002528.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 396475 pyrD 1110058 pyrD Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydroorotate dehydrogenase 2 NP_240180.1 395612 D 107806 CDS NP_240181.1 15616968 1110059 396651..398756 1 NC_002528.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA; 23S rRNA m(2)G2445 methyltransferase 398756 rlmL 1110059 rlmL Buchnera aphidicola str. APS (Acyrthosiphon pisum) 23S rRNA m(2)G2445 methyltransferase NP_240181.1 396651 D 107806 CDS NP_240182.1 15616969 1110060 398776..400566 1 NC_002528.1 ABC transporter ATP-binding protein 400566 uup 1110060 uup Buchnera aphidicola str. APS (Acyrthosiphon pisum) ABC transporter ATP-binding protein NP_240182.1 398776 D 107806 CDS NP_240183.1 15616970 1110061 complement(400570..401544) 1 NC_002528.1 hypothetical protein 401544 yceA 1110061 yceA Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240183.1 400570 R 107806 CDS NP_240184.1 15616971 1109720 complement(401601..404468) 1 NC_002528.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 404468 valS 1109720 valS Buchnera aphidicola str. APS (Acyrthosiphon pisum) valyl-tRNA synthetase NP_240184.1 401601 R 107806 CDS NP_240185.1 15616972 1109721 complement(404545..406044) 1 NC_002528.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 406044 pepA 1109721 pepA Buchnera aphidicola str. APS (Acyrthosiphon pisum) leucyl aminopeptidase NP_240185.1 404545 R 107806 CDS NP_240186.1 15616973 1109722 406304..407320 1 NC_002528.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.; ornithine carbamoyltransferase subunit I 407320 argF 1109722 argF Buchnera aphidicola str. APS (Acyrthosiphon pisum) ornithine carbamoyltransferase subunit I NP_240186.1 406304 D 107806 CDS NP_240187.1 15616974 1109723 407439..408371 1 NC_002528.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 408371 pyrB 1109723 pyrB Buchnera aphidicola str. APS (Acyrthosiphon pisum) aspartate carbamoyltransferase NP_240187.1 407439 D 107806 CDS NP_240188.1 15616975 1109724 408379..408843 1 NC_002528.1 involved in the allosteric regulation of aspartate carbamoyltransferase; aspartate carbamoyltransferase 408843 pyrI 1109724 pyrI Buchnera aphidicola str. APS (Acyrthosiphon pisum) aspartate carbamoyltransferase NP_240188.1 408379 D 107806 CDS NP_240189.1 15616976 1109725 408889..409275 1 NC_002528.1 hypothetical protein 409275 yhaR 1109725 yhaR Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240189.1 408889 D 107806 CDS NP_240190.1 15616977 1109726 complement(409362..411167) 1 NC_002528.1 ATP-dependent RNA helicase DeaD 411167 deaD 1109726 deaD Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent RNA helicase DeaD NP_240190.1 409362 R 107806 CDS NP_240191.1 15616978 1109727 complement(411548..413671) 1 NC_002528.1 polynucleotide phosphorylase 413671 pnp 1109727 pnp Buchnera aphidicola str. APS (Acyrthosiphon pisum) polynucleotide phosphorylase NP_240191.1 411548 R 107806 CDS NP_240192.1 15616979 1109728 complement(413873..414142) 1 NC_002528.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 414142 rpsO 1109728 rpsO Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S15 NP_240192.1 413873 R 107806 CDS NP_240193.1 15616980 1109729 complement(414247..415185) 1 NC_002528.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 415185 truB 1109729 truB Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA pseudouridine synthase B NP_240193.1 414247 R 107806 CDS NP_240194.1 15616981 1109730 complement(415223..415585) 1 NC_002528.1 ribosome-binding factor A 415585 rbfA 1109730 rbfA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribosome-binding factor A NP_240194.1 415223 R 107806 CDS NP_240195.1 15616982 1109731 complement(415631..418225) 1 NC_002528.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 418225 infB 1109731 infB Buchnera aphidicola str. APS (Acyrthosiphon pisum) translation initiation factor IF-2 NP_240195.1 415631 R 107806 CDS NP_240196.1 15616983 1109732 complement(418243..419733) 1 NC_002528.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 419733 nusA 1109732 nusA Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription elongation factor NusA NP_240196.1 418243 R 107806 CDS NP_240197.1 15616984 1109733 complement(420206..420535) 1 NC_002528.1 preprotein translocase subunit SecG 420535 secG 1109733 secG Buchnera aphidicola str. APS (Acyrthosiphon pisum) preprotein translocase subunit SecG NP_240197.1 420206 R 107806 CDS NP_240198.1 15616985 1109734 complement(420797..422131) 1 NC_002528.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 422131 glmM 1109734 glmM Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoglucosamine mutase NP_240198.1 420797 R 107806 CDS NP_240199.2 28952053 1109735 complement(422351..424186) 1 NC_002528.1 cell division protein FtsH 424186 hflB 1109735 hflB Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsH NP_240199.2 422351 R 107806 CDS NP_240200.1 15616987 1109736 complement(424252..424872) 1 NC_002528.1 cell division protein FtsJ 424872 ftsJ 1109736 ftsJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) cell division protein FtsJ NP_240200.1 424252 R 107806 CDS NP_240201.1 15616988 1109737 complement(424946..425425) 1 NC_002528.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 425425 greA 1109737 greA Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription elongation factor GreA NP_240201.1 424946 R 107806 CDS NP_240202.1 15616989 1109738 425949..426191 1 NC_002528.1 hypothetical protein 426191 yrbA 1109738 yrbA Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240202.1 425949 D 107806 CDS NP_240203.1 15616990 1109739 426253..427503 1 NC_002528.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 427503 murA 1109739 murA Buchnera aphidicola str. APS (Acyrthosiphon pisum) UDP-N-acetylglucosamine 1-carboxyvinyltransferase NP_240203.1 426253 D 107806 CDS NP_240204.1 15616991 1109740 427642..427968 1 NC_002528.1 50S ribosomal protein L21 427968 rplU 1109740 rplU Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L21 NP_240204.1 427642 D 107806 CDS NP_240205.1 15616992 1109741 427973..428227 1 NC_002528.1 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 428227 rpmA 1109741 rpmA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L27 NP_240205.1 427973 D 107806 CDS NP_240206.1 15616993 1109742 428379..429383 1 NC_002528.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 429383 obgE 1109742 obgE Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTPase ObgE NP_240206.1 428379 D 107806 CDS NP_240207.1 15616994 1109743 complement(429451..429843) 1 NC_002528.1 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 429843 rpsI 1109743 rpsI Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S9 NP_240207.1 429451 R 107806 CDS NP_240208.1 15616995 1109744 complement(429864..430292) 1 NC_002528.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 430292 rplM 1109744 rplM Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L13 NP_240208.1 429864 R 107806 CDS NP_240209.1 15616996 1109745 430544..431701 1 NC_002528.1 prephenate dehydratase; chorismate mutase 431701 pheA 1109745 pheA Buchnera aphidicola str. APS (Acyrthosiphon pisum) chorismate mutase NP_240209.1 430544 D 107806 CDS NP_240210.1 15616997 1109746 431883..433238 1 NC_002528.1 signal recognition particle protein 433238 ffh 1109746 ffh Buchnera aphidicola str. APS (Acyrthosiphon pisum) signal recognition particle protein NP_240210.1 431883 D 107806 CDS NP_240211.1 15616998 1109747 433347..433586 1 NC_002528.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 433586 rpsP 1109747 rpsP Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S16 NP_240211.1 433347 D 107806 CDS NP_240212.1 15616999 1109748 433588..434118 1 NC_002528.1 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 434118 rimM 1109748 rimM Buchnera aphidicola str. APS (Acyrthosiphon pisum) 16S rRNA-processing protein RimM NP_240212.1 433588 D 107806 CDS NP_240213.1 15617000 1109749 434133..434846 1 NC_002528.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 434846 trmD 1109749 trmD Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA (guanine-N(1)-)-methyltransferase NP_240213.1 434133 D 107806 CDS NP_240214.1 15617001 1109750 434945..435292 1 NC_002528.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 435292 rplS 1109750 rplS Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L19 NP_240214.1 434945 D 107806 CDS NP_240215.1 15617002 1109751 complement(435376..436827) 1 NC_002528.1 TldD protein 436827 tldD 1109751 tldD Buchnera aphidicola str. APS (Acyrthosiphon pisum) TldD protein NP_240215.1 435376 R 107806 CDS NP_240216.1 15617003 1109752 436985..437437 1 NC_002528.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 437437 aroD 1109752 aroD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-dehydroquinate dehydratase NP_240216.1 436985 D 107806 CDS NP_240217.1 15617004 1109753 complement(437630..437926) 1 NC_002528.1 factor-for-inversion stimulation protein 437926 fis 1109753 fis Buchnera aphidicola str. APS (Acyrthosiphon pisum) factor-for-inversion stimulation protein NP_240217.1 437630 R 107806 CDS NP_240218.1 15617005 1109754 complement(438095..439033) 1 NC_002528.1 ribosomal large subunit pseudouridine synthase D 439033 rluD 1109754 rluD Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribosomal large subunit pseudouridine synthase D NP_240218.1 438095 R 107806 CDS NP_240219.1 15617006 1109755 439198..439938 1 NC_002528.1 hypothetical protein 439938 yfiO 1109755 yfiO Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240219.1 439198 D 107806 CDS NP_240220.1 15617007 1109756 440103..442739 1 NC_002528.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 442739 alaS 1109756 alaS Buchnera aphidicola str. APS (Acyrthosiphon pisum) alanyl-tRNA synthetase NP_240220.1 440103 D 107806 CDS NP_240221.1 15617008 1109757 442934..443107 1 NC_002528.1 carbon storage regulator 443107 csrA 1109757 csrA Buchnera aphidicola str. APS (Acyrthosiphon pisum) carbon storage regulator NP_240221.1 442934 D 107806 CDS NP_240222.1 15617009 1109758 443565..445121 1 NC_002528.1 involved in the first step of glutathione biosynthesis; glutamate--cysteine ligase 445121 gshA 1109758 gshA Buchnera aphidicola str. APS (Acyrthosiphon pisum) glutamate--cysteine ligase NP_240222.1 443565 D 107806 CDS NP_240223.1 15617010 1109759 complement(445268..446404) 1 NC_002528.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 446404 metK 1109759 metK Buchnera aphidicola str. APS (Acyrthosiphon pisum) S-adenosylmethionine synthetase NP_240223.1 445268 R 107806 CDS NP_240224.1 15617011 1109760 446639..447391 1 NC_002528.1 endonuclease I 447391 endA 1109760 endA Buchnera aphidicola str. APS (Acyrthosiphon pisum) endonuclease I NP_240224.1 446639 D 107806 CDS NP_240225.1 15617012 1109761 447363..448124 1 NC_002528.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 448124 yggJ 1109761 yggJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 16S ribosomal RNA methyltransferase RsmE NP_240225.1 447363 D 107806 CDS NP_240226.1 15617013 1109762 complement(448198..448869) 1 NC_002528.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 448869 rpiA 1109762 rpiA Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribose-5-phosphate isomerase A NP_240226.1 448198 R 107806 CDS NP_240227.1 15617014 1109763 449495..451210 1 NC_002528.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; glutaminyl-tRNA synthetase 451210 glnS 1109763 glnS Buchnera aphidicola str. APS (Acyrthosiphon pisum) glutaminyl-tRNA synthetase NP_240227.1 449495 D 107806 CDS NP_240228.1 15617015 1109764 451384..453021 1 NC_002528.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 453021 pyrG 1109764 pyrG Buchnera aphidicola str. APS (Acyrthosiphon pisum) CTP synthetase NP_240228.1 451384 D 107806 CDS NP_240229.1 15617016 1109765 453051..454355 1 NC_002528.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 454355 eno 1109765 eno Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphopyruvate hydratase NP_240229.1 453051 D 107806 CDS NP_240230.1 15617017 1109766 complement(454513..455517) 1 NC_002528.1 lipoprotein NlpD 455517 nlpD 1109766 nlpD Buchnera aphidicola str. APS (Acyrthosiphon pisum) lipoprotein NlpD NP_240230.1 454513 R 107806 CDS NP_240231.1 15617018 1109767 complement(455608..456093) 1 NC_002528.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 456093 ispF 1109767 ispF Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_240231.1 455608 R 107806 CDS NP_240232.1 15617019 1109768 complement(456109..456822) 1 NC_002528.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 456822 ispD 1109768 ispD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_240232.1 456109 R 107806 CDS NP_240233.1 15617020 1109769 complement(456905..457120) 1 NC_002528.1 hypothetical protein 457120 ygbQ 1109769 ygbQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240233.1 456905 R 107806 CDS NP_240234.1 15617021 1109770 complement(457178..457798) 1 NC_002528.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis; adenylylsulfate kinase 457798 cysC 1109770 cysC Buchnera aphidicola str. APS (Acyrthosiphon pisum) adenylylsulfate kinase NP_240234.1 457178 R 107806 CDS NP_240235.1 15617022 1109771 complement(457799..459220) 1 NC_002528.1 sulfate adenylyltransferase 459220 cysN 1109771 cysN Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfate adenylyltransferase NP_240235.1 457799 R 107806 CDS NP_240236.1 15617023 1109772 complement(459239..460147) 1 NC_002528.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP; sulfate adenylyltransferase subunit 2 460147 cysD 1109772 cysD Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfate adenylyltransferase subunit 2 NP_240236.1 459239 R 107806 CDS NP_240237.1 15617024 1109773 complement(460157..461578) 1 NC_002528.1 precorrin-2 oxidase; siroheme synthase; ferrochelatase 461578 cysG 1109773 cysG Buchnera aphidicola str. APS (Acyrthosiphon pisum) ferrochelatase NP_240237.1 460157 R 107806 CDS NP_240238.1 15617025 1109774 complement(461917..462651) 1 NC_002528.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite; phosphoadenosine phosphosulfate reductase 462651 cysH 1109774 cysH Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoadenosine phosphosulfate reductase NP_240238.1 461917 R 107806 CDS NP_240239.1 15617026 1109775 complement(462667..464376) 1 NC_002528.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase subunit beta 464376 cysI 1109775 cysI Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfite reductase subunit beta NP_240239.1 462667 R 107806 CDS NP_240240.1 15617027 1109776 complement(464376..466181) 1 NC_002528.1 sulfite reductase (NADPH) flavoprotein alpha-component 466181 cysJ 1109776 cysJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfite reductase (NADPH) flavoprotein alpha-component NP_240240.1 464376 R 107806 CDS NP_240241.1 15617028 1109777 complement(466372..468780) 1 NC_002528.1 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 468780 mutS 1109777 mutS Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA mismatch repair protein MutS NP_240241.1 466372 R 107806 CDS NP_240242.1 15617029 1109778 468937..469575 1 NC_002528.1 thiol:disulfide interchange protein DsbA 469575 dsbA 1109778 dsbA Buchnera aphidicola str. APS (Acyrthosiphon pisum) thiol:disulfide interchange protein DsbA NP_240242.1 468937 D 107806 CDS NP_240243.1 15617030 1109779 469696..470556 1 NC_002528.1 DNA polymerase I 470556 polA 1109779 polA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase I NP_240243.1 469696 D 107806 CDS NP_240244.1 15617031 1109780 complement(470619..471236) 1 NC_002528.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 471236 engB 1109780 engB Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribosome biogenesis GTP-binding protein YsxC NP_240244.1 470619 R 107806 CDS NP_240245.1 15617032 1109781 471487..473310 1 NC_002528.1 GTP-binding protein TypA; GTP-binding protein BipA 473310 typA 1109781 typA Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP-binding protein BipA NP_240245.1 471487 D 107806 CDS NP_240246.1 15617033 1109782 complement(473433..474056) 1 NC_002528.1 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 474056 gmk 1109782 gmk Buchnera aphidicola str. APS (Acyrthosiphon pisum) guanylate kinase NP_240246.1 473433 R 107806 CDS NP_240247.1 15617034 1109783 complement(474156..475115) 1 NC_002528.1 hypothetical protein 475115 ygfZ 1109783 ygfZ Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240247.1 474156 R 107806 CDS NP_240248.1 15617035 1109784 475334..476383 1 NC_002528.1 peptide chain release factor 2 476383 prfB 1109784 prfB Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptide chain release factor 2 NP_240248.1 475334 D 107806 CDS NP_240249.1 15617036 1109785 476393..477913 1 NC_002528.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 477913 lysS 1109785 lysS Buchnera aphidicola str. APS (Acyrthosiphon pisum) lysyl-tRNA synthetase NP_240249.1 476393 D 107806 CDS NP_240250.1 15617037 1109786 477979..479226 1 NC_002528.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding; diaminopimelate decarboxylase 479226 lysA 1109786 lysA Buchnera aphidicola str. APS (Acyrthosiphon pisum) diaminopimelate decarboxylase NP_240250.1 477979 D 107806 CDS NP_240251.1 15617038 1109787 479292..480137 1 NC_002528.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 480137 lgt 1109787 lgt Buchnera aphidicola str. APS (Acyrthosiphon pisum) prolipoprotein diacylglyceryl transferase NP_240251.1 479292 D 107806 CDS NP_240252.1 15617039 1109788 480151..480945 1 NC_002528.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 480945 thyA 1109788 thyA Buchnera aphidicola str. APS (Acyrthosiphon pisum) thymidylate synthase NP_240252.1 480151 D 107806 CDS NP_240253.1 15617040 1109789 481012..482331 1 NC_002528.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase 482331 yleA 1109789 yleA Buchnera aphidicola str. APS (Acyrthosiphon pisum) (dimethylallyl)adenosine tRNA methylthiotransferase NP_240253.1 481012 D 107806 CDS NP_240254.1 15617041 1109790 482486..482821 1 NC_002528.1 hypothetical protein 482821 ybeY 1109790 ybeY Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240254.1 482486 D 107806 CDS NP_240255.1 15617042 1109791 482902..483777 1 NC_002528.1 hypothetical protein 483777 ybeX 1109791 ybeX Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240255.1 482902 D 107806 CDS NP_240256.1 15617043 1109792 483881..486460 1 NC_002528.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 486460 leuS 1109792 leuS Buchnera aphidicola str. APS (Acyrthosiphon pisum) leucyl-tRNA synthetase NP_240256.1 483881 D 107806 CDS NP_240257.1 15617044 1109793 486500..487495 1 NC_002528.1 DNA polymerase III subunit delta 487495 holA 1109793 holA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III subunit delta NP_240257.1 486500 D 107806 CDS NP_240258.1 15617045 1109794 487518..488162 1 NC_002528.1 hypothetical protein 488162 ybeN 1109794 ybeN Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240258.1 487518 D 107806 CDS NP_240259.1 15617046 1109795 488223..488453 1 NC_002528.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs; sulfur transfer protein SirA 488453 yhhP 1109795 yhhP Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfur transfer protein SirA NP_240259.1 488223 D 107806 CDS NP_240260.1 15617047 1109796 complement(488600..489715) 1 NC_002528.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 489715 asd 1109796 asd Buchnera aphidicola str. APS (Acyrthosiphon pisum) aspartate-semialdehyde dehydrogenase NP_240260.1 488600 R 107806 CDS NP_240261.2 28952054 1109797 490011..490601 1 NC_002528.1 YhgN; Ec0197; hydrolyzes nucleoside triphosphates with an O6 atom-containing purine base to nucleoside monophosphate and pyrophosphate; seems to play a role in the elimination of aberrant purine-derived nucleotides containing the 6-keto group; shows preference for deoxyinosine triphosphate and xanthosine triphosphate over standard nucleoside triphosphates (dATP, dCTP, dGTP, and dTTP); putative dITP- and XTP- hydrolase 490601 yhgN 1109797 yhgN Buchnera aphidicola str. APS (Acyrthosiphon pisum) putative dITP- and XTP- hydrolase NP_240261.2 490011 D 107806 CDS NP_240262.1 15617049 1109798 490715..491887 1 NC_002528.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 491887 pgk 1109798 pgk Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphoglycerate kinase NP_240262.1 490715 D 107806 CDS NP_240263.1 15617050 1109799 491903..492979 1 NC_002528.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 492979 fba 1109799 fba Buchnera aphidicola str. APS (Acyrthosiphon pisum) fructose-bisphosphate aldolase NP_240263.1 491903 D 107806 CDS NP_240264.2 28952055 1109800 493115..493960 1 NC_002528.1 hypothetical protein 493960 yggB 1109800 yggB Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240264.2 493115 D 107806 CDS NP_240265.1 15617052 1109801 494019..497231 1 NC_002528.1 exodeoxyribonuclease V 497231 recC 1109801 recC Buchnera aphidicola str. APS (Acyrthosiphon pisum) exodeoxyribonuclease V NP_240265.1 494019 D 107806 CDS NP_240266.1 15617053 1109802 497248..500772 1 NC_002528.1 exodeoxyribonuclease V 500772 recB 1109802 recB Buchnera aphidicola str. APS (Acyrthosiphon pisum) exodeoxyribonuclease V NP_240266.1 497248 D 107806 CDS NP_240267.1 15617054 1109803 500778..502586 1 NC_002528.1 exodeoxyribonuclease V 502586 recD 1109803 recD Buchnera aphidicola str. APS (Acyrthosiphon pisum) exodeoxyribonuclease V NP_240267.1 500778 D 107806 CDS NP_240268.1 15617055 1109804 complement(502625..503953) 1 NC_002528.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; N-acetylglutamate synthase 503953 argA 1109804 argA Buchnera aphidicola str. APS (Acyrthosiphon pisum) N-acetylglutamate synthase NP_240268.1 502625 R 107806 CDS NP_240269.1 15617056 1109805 504321..505400 1 NC_002528.1 membrane-bound, lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; murein transglycosylase A 505400 mltA 1109805 mltA Buchnera aphidicola str. APS (Acyrthosiphon pisum) murein transglycosylase A NP_240269.1 504321 D 107806 CDS NP_240270.1 15617057 1109806 505439..505921 1 NC_002528.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 505921 ribH 1109806 ribH Buchnera aphidicola str. APS (Acyrthosiphon pisum) 6,7-dimethyl-8-ribityllumazine synthase NP_240270.1 505439 D 107806 CDS NP_240271.1 15617058 1109807 505951..506922 1 NC_002528.1 thiamin-monophosphate kinase 506922 thiL 1109807 thiL Buchnera aphidicola str. APS (Acyrthosiphon pisum) thiamin-monophosphate kinase NP_240271.1 505951 D 107806 CDS NP_240272.1 15617059 1109808 506978..507403 1 NC_002528.1 riboflavin deaminase 507403 ribD1 1109808 ribD1 Buchnera aphidicola str. APS (Acyrthosiphon pisum) riboflavin deaminase NP_240272.1 506978 D 107806 CDS NP_240273.1 15617060 1109809 507446..508069 1 NC_002528.1 riboflavin reductase 508069 ribD2 1109809 ribD2 Buchnera aphidicola str. APS (Acyrthosiphon pisum) riboflavin reductase NP_240273.1 507446 D 107806 CDS NP_240274.1 15617061 1109810 508106..508537 1 NC_002528.1 Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB 508537 nusB 1109810 nusB Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription antitermination protein NusB NP_240274.1 508106 D 107806 CDS NP_240275.1 15617062 1109811 complement(508592..510418) 1 NC_002528.1 Dxs protein; catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 510418 dxs 1109811 dxs Buchnera aphidicola str. APS (Acyrthosiphon pisum) 1-deoxy-D-xylulose-5-phosphate synthase NP_240275.1 508592 R 107806 CDS NP_240276.1 15617063 1109812 complement(510476..511324) 1 NC_002528.1 geranyltranstransferase 511324 ispA 1109812 ispA Buchnera aphidicola str. APS (Acyrthosiphon pisum) geranyltranstransferase NP_240276.1 510476 R 107806 CDS NP_240277.1 15617064 1109813 complement(511376..512548) 1 NC_002528.1 hypothetical protein 512548 yajR 1109813 yajR Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240277.1 511376 R 107806 CDS NP_240278.1 15617065 1109814 512622..512966 1 NC_002528.1 hypothetical protein 512966 yccK 1109814 yccK Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240278.1 512622 D 107806 CDS NP_240279.1 15617066 1109815 complement(512987..513844) 1 NC_002528.1 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 513844 cyoE 1109815 cyoE Buchnera aphidicola str. APS (Acyrthosiphon pisum) protoheme IX farnesyltransferase NP_240279.1 512987 R 107806 CDS NP_240280.1 15617067 1109816 complement(513872..514189) 1 NC_002528.1 cytochrome O ubiquinol oxidase subunit IV 514189 cyoD 1109816 cyoD Buchnera aphidicola str. APS (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit IV NP_240280.1 513872 R 107806 CDS NP_240281.1 15617068 1109817 complement(514189..514806) 1 NC_002528.1 cytochrome O ubiquinol oxidase subunit III 514806 cyoC 1109817 cyoC Buchnera aphidicola str. APS (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit III NP_240281.1 514189 R 107806 CDS NP_240282.1 15617069 1109818 complement(514803..516791) 1 NC_002528.1 cytochrome O ubiquinol oxidase subunit I 516791 cyoB 1109818 cyoB Buchnera aphidicola str. APS (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit I NP_240282.1 514803 R 107806 CDS NP_240283.1 15617070 1109819 complement(516796..517686) 1 NC_002528.1 cytochrome O ubiquinol oxidase subunit II 517686 cyoA 1109819 cyoA Buchnera aphidicola str. APS (Acyrthosiphon pisum) cytochrome O ubiquinol oxidase subunit II NP_240283.1 516796 R 107806 CDS NP_240284.1 15617071 1109820 517985..518299 1 NC_002528.1 BolA protein 518299 bolA 1109820 bolA Buchnera aphidicola str. APS (Acyrthosiphon pisum) BolA protein NP_240284.1 517985 D 107806 CDS NP_240285.1 15617072 1109821 518435..519763 1 NC_002528.1 trigger factor 519763 tig 1109821 tig Buchnera aphidicola str. APS (Acyrthosiphon pisum) trigger factor NP_240285.1 518435 D 107806 CDS NP_240286.1 15617073 1109822 519898..520524 1 NC_002528.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 520524 clpP 1109822 clpP Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent Clp protease proteolytic subunit NP_240286.1 519898 D 107806 CDS NP_240287.1 15617074 1109823 520623..521912 1 NC_002528.1 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 521912 clpX 1109823 clpX Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent protease ATP-binding subunit ClpX NP_240287.1 520623 D 107806 CDS NP_240288.1 15617075 1109824 522104..524437 1 NC_002528.1 ATP-dependent protease LA 524437 lon 1109824 lon Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent protease LA NP_240288.1 522104 D 107806 CDS NP_240289.1 15617076 1109825 524579..526450 1 NC_002528.1 peptidyl-prolyl cis-trans isomerase D 526450 ppiD 1109825 ppiD Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptidyl-prolyl cis-trans isomerase D NP_240289.1 524579 D 107806 CDS NP_240290.1 15617077 1109826 527423..529192 1 NC_002528.1 multidrug resistance-like ATP-binding protein Mdl 529192 mdl 1109826 mdl Buchnera aphidicola str. APS (Acyrthosiphon pisum) multidrug resistance-like ATP-binding protein Mdl NP_240290.1 527423 D 107806 CDS NP_240291.1 15617078 1109827 529164..530936 1 NC_002528.1 multidrug resistance-like ATP-binding protein MdlB 530936 mdlB 1109827 mdlB Buchnera aphidicola str. APS (Acyrthosiphon pisum) multidrug resistance-like ATP-binding protein MdlB NP_240291.1 529164 D 107806 CDS NP_240292.1 15617079 1109828 531231..532316 1 NC_002528.1 DNA polymerase III subunits gamma and tau 532316 dnaX 1109828 dnaX Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA polymerase III subunits gamma and tau NP_240292.1 531231 D 107806 CDS NP_240293.1 15617080 1109829 532636..532965 1 NC_002528.1 hypothetical protein 532965 ybaB 1109829 ybaB Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240293.1 532636 D 107806 CDS NP_240294.1 15617081 1109830 533111..534985 1 NC_002528.1 molecular chaperone; heat shock protein 90 534985 htpG 1109830 htpG Buchnera aphidicola str. APS (Acyrthosiphon pisum) heat shock protein 90 NP_240294.1 533111 D 107806 CDS NP_240295.1 15617082 1109831 535058..535705 1 NC_002528.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 535705 adk 1109831 adk Buchnera aphidicola str. APS (Acyrthosiphon pisum) adenylate kinase NP_240295.1 535058 D 107806 CDS NP_240296.1 15617083 1109832 535936..536793 1 NC_002528.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 536793 folD 1109832 folD Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase NP_240296.1 535936 D 107806 CDS NP_240297.1 15617084 1109833 complement(536790..538184) 1 NC_002528.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 538184 cysS 1109833 cysS Buchnera aphidicola str. APS (Acyrthosiphon pisum) cysteinyl-tRNA synthetase NP_240297.1 536790 R 107806 CDS NP_240298.1 15617085 1109834 538445..538708 1 NC_002528.1 hypothetical protein 538708 ybeD 1109834 ybeD Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240298.1 538445 D 107806 CDS NP_240299.1 15617086 1109835 complement(538815..539024) 1 NC_002528.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator; cold shock protein CspE 539024 cspE 1109835 cspE Buchnera aphidicola str. APS (Acyrthosiphon pisum) cold shock protein CspE NP_240299.1 538815 R 107806 CDS NP_240300.1 15617087 1109836 complement(542838..543659) 1 NC_002528.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase 543659 aroE 1109836 aroE Buchnera aphidicola str. APS (Acyrthosiphon pisum) shikimate 5-dehydrogenase NP_240300.1 542838 R 107806 CDS NP_240301.1 15617088 1109837 complement(543652..544179) 1 NC_002528.1 hypothetical protein 544179 yrdC 1109837 yrdC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240301.1 543652 R 107806 CDS NP_240302.1 15617089 1109838 complement(544277..544750) 1 NC_002528.1 Smg protein 544750 smg 1109838 smg Buchnera aphidicola str. APS (Acyrthosiphon pisum) Smg protein NP_240302.1 544277 R 107806 CDS NP_240303.1 15617090 1109839 544994..545515 1 NC_002528.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 545515 def 1109839 def Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptide deformylase NP_240303.1 544994 D 107806 CDS NP_240304.1 15617091 1109840 545523..546467 1 NC_002528.1 methionyl-tRNA formyltransferase 546467 fmt 1109840 fmt Buchnera aphidicola str. APS (Acyrthosiphon pisum) methionyl-tRNA formyltransferase NP_240304.1 545523 D 107806 CDS NP_240305.1 15617092 1109841 complement(546594..546986) 1 NC_002528.1 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 546986 rplQ 1109841 rplQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L17 NP_240305.1 546594 R 107806 CDS NP_240306.1 15617093 1109842 complement(547031..548020) 1 NC_002528.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 548020 rpoA 1109842 rpoA Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA-directed RNA polymerase subunit alpha NP_240306.1 547031 R 107806 CDS NP_240307.1 15617094 1109843 complement(548049..548669) 1 NC_002528.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 548669 rpsD 1109843 rpsD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S4 NP_240307.1 548049 R 107806 CDS NP_240308.1 15617095 1109844 complement(548695..549090) 1 NC_002528.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 549090 rpsK 1109844 rpsK Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S11 NP_240308.1 548695 R 107806 CDS NP_240309.1 15617096 1109845 complement(549108..549464) 1 NC_002528.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 549464 rpsM 1109845 rpsM Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S13 NP_240309.1 549108 R 107806 CDS NP_240310.1 15617097 1109846 complement(549558..549674) 1 NC_002528.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 549674 rpmJ 1109846 rpmJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L36 NP_240310.1 549558 R 107806 CDS NP_240311.1 15617098 1109847 complement(549700..551013) 1 NC_002528.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 551013 secY 1109847 secY Buchnera aphidicola str. APS (Acyrthosiphon pisum) preprotein translocase subunit SecY NP_240311.1 549700 R 107806 CDS NP_240312.1 15617099 1109848 complement(551024..551458) 1 NC_002528.1 late assembly protein; 50S ribosomal protein L15 551458 rplO 1109848 rplO Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L15 NP_240312.1 551024 R 107806 CDS NP_240313.1 15617100 1109849 complement(551463..551642) 1 NC_002528.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 551642 rpmD 1109849 rpmD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L30 NP_240313.1 551463 R 107806 CDS NP_240314.1 15617101 1109850 complement(551652..552155) 1 NC_002528.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 552155 rpsE 1109850 rpsE Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S5 NP_240314.1 551652 R 107806 CDS NP_240315.1 15617102 1109851 complement(552171..552539) 1 NC_002528.1 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 552539 rplR 1109851 rplR Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L18 NP_240315.1 552171 R 107806 CDS NP_240316.3 161353756 1109852 complement(552541..553077) 1 NC_002528.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 553077 rplF 1109852 rplF Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L6 NP_240316.3 552541 R 107806 CDS NP_240317.1 15617104 1109853 complement(553088..553480) 1 NC_002528.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 553480 rpsH 1109853 rpsH Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S8 NP_240317.1 553088 R 107806 CDS NP_240318.1 15617105 1109854 complement(553509..553814) 1 NC_002528.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 553814 rpsN 1109854 rpsN Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S14 NP_240318.1 553509 R 107806 CDS NP_240319.1 15617106 1109855 complement(553832..554371) 1 NC_002528.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 554371 rplE 1109855 rplE Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L5 NP_240319.1 553832 R 107806 CDS NP_240320.1 15617107 1109856 complement(554386..554700) 1 NC_002528.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 554700 rplX 1109856 rplX Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L24 NP_240320.1 554386 R 107806 CDS NP_240321.1 15617108 1109857 complement(554726..555094) 1 NC_002528.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 555094 rplN 1109857 rplN Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L14 NP_240321.1 554726 R 107806 CDS NP_240322.1 15617109 1109858 complement(555209..555460) 1 NC_002528.1 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 555460 rpsQ 1109858 rpsQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S17 NP_240322.1 555209 R 107806 CDS NP_240323.1 15617110 1109859 complement(555460..555657) 1 NC_002528.1 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 555657 rpmC 1109859 rpmC Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L29 NP_240323.1 555460 R 107806 CDS NP_240324.1 15617111 1109860 complement(555657..556067) 1 NC_002528.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 556067 rplP 1109860 rplP Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L16 NP_240324.1 555657 R 107806 CDS NP_240325.1 15617112 1109861 complement(556088..556789) 1 NC_002528.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 556789 rpsC 1109861 rpsC Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S3 NP_240325.1 556088 R 107806 CDS NP_240326.1 15617113 1109862 complement(556808..557140) 1 NC_002528.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 557140 rplV 1109862 rplV Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L22 NP_240326.1 556808 R 107806 CDS NP_240327.1 15617114 1109863 complement(557176..557454) 1 NC_002528.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 557454 rpsS 1109863 rpsS Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S19 NP_240327.1 557176 R 107806 CDS NP_240328.1 15617115 1109864 complement(557474..558295) 1 NC_002528.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 558295 rplB 1109864 rplB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L2 NP_240328.1 557474 R 107806 CDS NP_240329.1 15617116 1109865 complement(558310..558612) 1 NC_002528.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 558612 rplW 1109865 rplW Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L23 NP_240329.1 558310 R 107806 CDS NP_240330.1 15617117 1109866 complement(558609..559214) 1 NC_002528.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 559214 rplD 1109866 rplD Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L4 NP_240330.1 558609 R 107806 CDS NP_240331.1 15617118 1109867 complement(559232..559861) 1 NC_002528.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 559861 rplC 1109867 rplC Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L3 NP_240331.1 559232 R 107806 CDS NP_240332.1 15617119 1109868 complement(559892..560203) 1 NC_002528.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 560203 rpsJ 1109868 rpsJ Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S10 NP_240332.1 559892 R 107806 CDS NP_240333.2 28952057 1109869 complement(560535..561719) 1 NC_002528.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 561719 tufB 1109869 tufB Buchnera aphidicola str. APS (Acyrthosiphon pisum) elongation factor Tu NP_240333.2 560535 R 107806 CDS NP_240334.1 15617121 1109870 complement(561787..563895) 1 NC_002528.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 563895 fusA 1109870 fusA Buchnera aphidicola str. APS (Acyrthosiphon pisum) elongation factor G NP_240334.1 561787 R 107806 CDS NP_240335.1 15617122 1109871 complement(564010..564480) 1 NC_002528.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 564480 rpsG 1109871 rpsG Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S7 NP_240335.1 564010 R 107806 CDS NP_240336.1 15617123 1109872 complement(564522..564896) 1 NC_002528.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 564896 rpsL 1109872 rpsL Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S12 NP_240336.1 564522 R 107806 CDS NP_240337.2 28952058 1109873 complement(565030..565317) 1 NC_002528.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusB 565317 yheL 1109873 yheL Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfur transfer complex subunit TusB NP_240337.2 565030 R 107806 CDS NP_240338.1 15617125 1109874 complement(565329..565688) 1 NC_002528.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur relay protein TusC 565688 yheM 1109874 yheM Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfur relay protein TusC NP_240338.1 565329 R 107806 CDS NP_240339.1 15617126 1109875 complement(565707..566093) 1 NC_002528.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs; sulfur transfer complex subunit TusD 566093 yheN 1109875 yheN Buchnera aphidicola str. APS (Acyrthosiphon pisum) sulfur transfer complex subunit TusD NP_240339.1 565707 R 107806 CDS NP_240340.1 15617127 1109876 complement(566176..566901) 1 NC_002528.1 FKBP-type peptidylprolyl isomerase 566901 fkpA 1109876 fkpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) FKBP-type peptidylprolyl isomerase NP_240340.1 566176 R 107806 CDS NP_240341.1 15617128 1109877 complement(567364..568590) 1 NC_002528.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate; bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein 568590 argD 1109877 argD Buchnera aphidicola str. APS (Acyrthosiphon pisum) bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein NP_240341.1 567364 R 107806 CDS NP_240342.1 15617129 1109878 568906..570072 1 NC_002528.1 hypothetical protein 570072 yhfC 1109878 yhfC Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240342.1 568906 D 107806 CDS NP_240343.1 15617130 1109879 complement(570134..571141) 1 NC_002528.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase 571141 trpS 1109879 trpS Buchnera aphidicola str. APS (Acyrthosiphon pisum) tryptophanyl-tRNA synthetase NP_240343.1 570134 R 107806 CDS NP_240344.1 15617131 1109880 complement(571164..571850) 1 NC_002528.1 ribulose-phosphate 3-epimerase 571850 rpe 1109880 rpe Buchnera aphidicola str. APS (Acyrthosiphon pisum) ribulose-phosphate 3-epimerase NP_240344.1 571164 R 107806 CDS NP_240345.1 15617132 1109881 complement(572734..573825) 1 NC_002528.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 573825 aroB 1109881 aroB Buchnera aphidicola str. APS (Acyrthosiphon pisum) 3-dehydroquinate synthase NP_240345.1 572734 R 107806 CDS NP_240346.1 15617133 1109882 complement(573843..574364) 1 NC_002528.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase I 574364 aroK 1109882 aroK Buchnera aphidicola str. APS (Acyrthosiphon pisum) shikimate kinase I NP_240346.1 573843 R 107806 CDS NP_240347.1 15617134 1109883 complement(574967..575671) 1 NC_002528.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 575671 deoD 1109883 deoD Buchnera aphidicola str. APS (Acyrthosiphon pisum) purine nucleoside phosphorylase NP_240347.1 574967 R 107806 CDS NP_240348.1 15617135 1109884 complement(575715..576938) 1 NC_002528.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 576938 deoB 1109884 deoB Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphopentomutase NP_240348.1 575715 R 107806 CDS NP_240349.1 15617136 1109885 complement(576996..578576) 1 NC_002528.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 578576 prfC 1109885 prfC Buchnera aphidicola str. APS (Acyrthosiphon pisum) peptide chain release factor 3 NP_240349.1 576996 R 107806 CDS NP_240350.1 15617137 1109886 complement(579687..580265) 1 NC_002528.1 hypothetical protein 580265 yhgI 1109886 yhgI Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240350.1 579687 R 107806 CDS NP_240351.1 15617138 1109887 complement(580878..581393) 1 NC_002528.1 single-strand binding protein 581393 ssb 1109887 ssb Buchnera aphidicola str. APS (Acyrthosiphon pisum) single-strand binding protein NP_240351.1 580878 R 107806 CDS NP_240352.2 28952059 1109888 582063..583460 1 NC_002528.1 replicative DNA helicase 583460 dnaB 1109888 dnaB Buchnera aphidicola str. APS (Acyrthosiphon pisum) replicative DNA helicase NP_240352.2 582063 D 107806 CDS NP_240353.1 15617140 1109889 583707..584669 1 NC_002528.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 584669 gshB 1109889 gshB Buchnera aphidicola str. APS (Acyrthosiphon pisum) glutathione synthetase NP_240353.1 583707 D 107806 CDS NP_240354.1 15617141 1109890 584680..585087 1 NC_002528.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 585087 yqgF 1109890 yqgF Buchnera aphidicola str. APS (Acyrthosiphon pisum) Holliday junction resolvase-like protein NP_240354.1 584680 D 107806 CDS NP_240355.1 15617142 1109891 585205..585807 1 NC_002528.1 hypothetical protein 585807 yggS 1109891 yggS Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240355.1 585205 D 107806 CDS NP_240356.1 15617143 1109892 585850..586980 1 NC_002528.1 hypothetical protein 586980 yggW 1109892 yggW Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240356.1 585850 D 107806 CDS NP_240357.1 15617144 1109893 complement(586987..587706) 1 NC_002528.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 587706 trmB 1109893 trmB Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA (guanine-N(7)-)-methyltransferase NP_240357.1 586987 R 107806 CDS NP_240358.1 15617145 1109894 587804..588856 1 NC_002528.1 A/G-specific adenine glycosylase 588856 mutY 1109894 mutY Buchnera aphidicola str. APS (Acyrthosiphon pisum) A/G-specific adenine glycosylase NP_240358.1 587804 D 107806 CDS NP_240359.1 15617146 1109895 588828..589109 1 NC_002528.1 hypothetical protein 589109 yggX 1109895 yggX Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240359.1 588828 D 107806 CDS NP_240360.1 15617147 1109896 589203..589991 1 NC_002528.1 glutamate racemase 589991 murI 1109896 murI Buchnera aphidicola str. APS (Acyrthosiphon pisum) glutamate racemase NP_240360.1 589203 D 107806 CDS NP_240361.1 15617148 1109897 complement(590182..591423) 1 NC_002528.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates; exonuclease I 591423 sbcB 1109897 sbcB Buchnera aphidicola str. APS (Acyrthosiphon pisum) exonuclease I NP_240361.1 590182 R 107806 CDS NP_240362.1 15617149 1109898 591503..591811 1 NC_002528.1 hypothetical protein 591811 yeeX 1109898 yeeX Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240362.1 591503 D 107806 CDS NP_240363.1 15617150 1109899 592193..592834 1 NC_002528.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 592834 pyrE 1109899 pyrE Buchnera aphidicola str. APS (Acyrthosiphon pisum) orotate phosphoribosyltransferase NP_240363.1 592193 D 107806 CDS NP_240364.1 15617151 1109900 complement(592846..593310) 1 NC_002528.1 catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 593310 dut 1109900 dut Buchnera aphidicola str. APS (Acyrthosiphon pisum) deoxyuridine 5'-triphosphate nucleotidohydrolase NP_240364.1 592846 R 107806 CDS NP_240365.1 15617152 1109901 complement(593354..594151) 1 NC_002528.1 CysQ protein 594151 cysQ 1109901 cysQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) CysQ protein NP_240365.1 593354 R 107806 CDS NP_240366.1 15617153 1109902 complement(594138..594590) 1 NC_002528.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 594590 rplI 1109902 rplI Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L9 NP_240366.1 594138 R 107806 CDS NP_240367.1 15617154 1109903 complement(594639..594866) 1 NC_002528.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 594866 rpsR 1109903 rpsR Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S18 NP_240367.1 594639 R 107806 CDS NP_240368.1 15617155 1109904 complement(594992..595333) 1 NC_002528.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 595333 rpsF 1109904 rpsF Buchnera aphidicola str. APS (Acyrthosiphon pisum) 30S ribosomal protein S6 NP_240368.1 594992 R 107806 CDS NP_240369.1 15617156 1109905 complement(595499..597736) 1 NC_002528.1 ribonuclease R; VacB protein 597736 vacB 1109905 vacB Buchnera aphidicola str. APS (Acyrthosiphon pisum) VacB protein NP_240369.1 595499 R 107806 CDS NP_240370.1 15617157 1109906 complement(597824..599125) 1 NC_002528.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 599125 purA 1109906 purA Buchnera aphidicola str. APS (Acyrthosiphon pisum) adenylosuccinate synthetase NP_240370.1 597824 R 107806 CDS NP_240371.1 15617158 1109907 complement(599175..600107) 1 NC_002528.1 with HflK inhibits proteolysis of lambda cII protein by FtsH; FtsH protease regulator HflC 600107 hflC 1109907 hflC Buchnera aphidicola str. APS (Acyrthosiphon pisum) FtsH protease regulator HflC NP_240371.1 599175 R 107806 CDS NP_240372.1 15617159 1109908 complement(600110..601330) 1 NC_002528.1 HflK protein 601330 hflK 1109908 hflK Buchnera aphidicola str. APS (Acyrthosiphon pisum) HflK protein NP_240372.1 600110 R 107806 CDS NP_240373.1 15617160 1109909 complement(601487..602395) 1 NC_002528.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 602395 miaA 1109909 miaA Buchnera aphidicola str. APS (Acyrthosiphon pisum) tRNA delta(2)-isopentenylpyrophosphate transferase NP_240373.1 601487 R 107806 CDS NP_240374.1 15617161 1109910 complement(602433..604187) 1 NC_002528.1 DNA mismatch repair protein MutL 604187 mutL 1109910 mutL Buchnera aphidicola str. APS (Acyrthosiphon pisum) DNA mismatch repair protein MutL NP_240374.1 602433 R 107806 CDS NP_240375.1 15617162 1109911 complement(604287..605444) 1 NC_002528.1 mannitol-1-phosphate 5-dehydrogenase 605444 mtlD 1109911 mtlD Buchnera aphidicola str. APS (Acyrthosiphon pisum) mannitol-1-phosphate 5-dehydrogenase NP_240375.1 604287 R 107806 CDS NP_240376.1 15617163 1109912 complement(605486..607384) 1 NC_002528.1 PTS system mannitol-specific transporter subunit IIABC 607384 mtlA 1109912 mtlA Buchnera aphidicola str. APS (Acyrthosiphon pisum) PTS system mannitol-specific transporter subunit IIABC NP_240376.1 605486 R 107806 CDS NP_240377.1 15617164 1109913 complement(607559..609208) 1 NC_002528.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 609208 pgi 1109913 pgi Buchnera aphidicola str. APS (Acyrthosiphon pisum) glucose-6-phosphate isomerase NP_240377.1 607559 R 107806 CDS NP_240378.1 15617165 1109914 609522..610076 1 NC_002528.1 3'-5' exoribonuclease specific for small oligoribonuclotides; oligoribonuclease 610076 orn 1109914 orn Buchnera aphidicola str. APS (Acyrthosiphon pisum) oligoribonuclease NP_240378.1 609522 D 107806 CDS NP_240379.1 15617166 1109915 610528..611241 1 NC_002528.1 N-acetylmuramoyl-L-alanine amidase 611241 amiB 1109915 amiB Buchnera aphidicola str. APS (Acyrthosiphon pisum) N-acetylmuramoyl-L-alanine amidase NP_240379.1 610528 D 107806 CDS NP_240380.1 15617167 1109916 complement(611349..611567) 1 NC_002528.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 611567 rpmE 1109916 rpmE Buchnera aphidicola str. APS (Acyrthosiphon pisum) 50S ribosomal protein L31 NP_240380.1 611349 R 107806 CDS NP_240381.2 228965512 1109917 612155..612685 1 NC_002528.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 612685 hslV 1109917 hslV Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent protease peptidase subunit NP_240381.2 612155 D 107806 CDS NP_240382.1 15617169 1109918 612698..614029 1 NC_002528.1 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 614029 hslU 1109918 hslU Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent protease ATP-binding subunit HslU NP_240382.1 612698 D 107806 CDS NP_240383.1 15617170 1109919 614236..614709 1 NC_002528.1 16 kDa heat shock protein A 614709 ibpA 1109919 ibpA Buchnera aphidicola str. APS (Acyrthosiphon pisum) 16 kDa heat shock protein A NP_240383.1 614236 D 107806 CDS NP_240384.1 15617171 1109920 614786..615544 1 NC_002528.1 ferredoxin-NADP reductase 615544 fpr 1109920 fpr Buchnera aphidicola str. APS (Acyrthosiphon pisum) ferredoxin-NADP reductase NP_240384.1 614786 D 107806 CDS NP_240385.1 15617172 1109921 complement(615562..616536) 1 NC_002528.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; lysyl-tRNA synthetase 616536 yjeA 1109921 yjeA Buchnera aphidicola str. APS (Acyrthosiphon pisum) lysyl-tRNA synthetase NP_240385.1 615562 R 107806 CDS NP_240386.1 15617173 1109922 616608..617105 1 NC_002528.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 617105 coaD 1109922 coaD Buchnera aphidicola str. APS (Acyrthosiphon pisum) phosphopantetheine adenylyltransferase NP_240386.1 616608 D 107806 CDS NP_240387.1 15617174 1109923 complement(617192..618295) 1 NC_002528.1 hypothetical protein 618295 yba3 1109923 yba3 Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240387.1 617192 R 107806 CDS NP_240388.1 15617175 1109924 complement(618288..618626) 1 NC_002528.1 hypothetical protein 618626 yba4 1109924 yba4 Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240388.1 618288 R 107806 CDS NP_240389.1 15617176 1109925 618781..619521 1 NC_002528.1 hypothetical protein 619521 yhiQ 1109925 yhiQ Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240389.1 618781 D 107806 CDS NP_240390.1 15617177 1109926 complement(619604..621076) 1 NC_002528.1 low-affinity inorganic phosphate transporter 621076 pitA 1109926 pitA Buchnera aphidicola str. APS (Acyrthosiphon pisum) low-affinity inorganic phosphate transporter NP_240390.1 619604 R 107806 CDS NP_240391.1 15617178 1109927 complement(621227..622459) 1 NC_002528.1 hypothetical protein 622459 ynfM 1109927 ynfM Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240391.1 621227 R 107806 CDS NP_240392.2 28952060 1109928 complement(622493..623347) 1 NC_002528.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 623347 dapF 1109928 dapF Buchnera aphidicola str. APS (Acyrthosiphon pisum) diaminopimelate epimerase NP_240392.2 622493 R 107806 CDS NP_240393.1 15617180 1109929 623535..623885 1 NC_002528.1 CyaY protein 623885 cyaY 1109929 cyaY Buchnera aphidicola str. APS (Acyrthosiphon pisum) CyaY protein NP_240393.1 623535 D 107806 CDS NP_240394.1 15617181 1109930 624014..624958 1 NC_002528.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 624958 hemC 1109930 hemC Buchnera aphidicola str. APS (Acyrthosiphon pisum) porphobilinogen deaminase NP_240394.1 624014 D 107806 CDS NP_240395.1 15617182 1109932 complement(626196..627455) 1 NC_002528.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 627455 rho 1109932 rho Buchnera aphidicola str. APS (Acyrthosiphon pisum) transcription termination factor Rho NP_240395.1 626196 R 107806 CDS NP_240396.1 15617183 1109933 complement(627585..627911) 1 NC_002528.1 thioredoxin 627911 trxA 1109933 trxA Buchnera aphidicola str. APS (Acyrthosiphon pisum) thioredoxin NP_240396.1 627585 R 107806 CDS NP_240397.1 15617184 1109934 complement(628113..630050) 1 NC_002528.1 ATP-dependent DNA helicase Rep 630050 rep 1109934 rep Buchnera aphidicola str. APS (Acyrthosiphon pisum) ATP-dependent DNA helicase Rep NP_240397.1 628113 R 107806 CDS NP_240398.1 15617185 1109935 complement(630120..631592) 1 NC_002528.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 631592 ilvC 1109935 ilvC Buchnera aphidicola str. APS (Acyrthosiphon pisum) ketol-acid reductoisomerase NP_240398.1 630120 R 107806 CDS NP_240399.1 15617186 1109936 complement(631640..633493) 1 NC_002528.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 633493 ilvD 1109936 ilvD Buchnera aphidicola str. APS (Acyrthosiphon pisum) dihydroxy-acid dehydratase NP_240399.1 631640 R 107806 CDS NP_240400.1 15617187 1109937 633980..635194 1 NC_002528.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 635194 yfhO 1109937 yfhO Buchnera aphidicola str. APS (Acyrthosiphon pisum) cysteine desulfurase NP_240400.1 633980 D 107806 CDS NP_240401.1 15617188 1109938 635225..635608 1 NC_002528.1 scaffold protein 635608 iscU 1109938 iscU Buchnera aphidicola str. APS (Acyrthosiphon pisum) scaffold protein NP_240401.1 635225 D 107806 CDS NP_240402.1 15617189 1109939 635703..636227 1 NC_002528.1 chaperone protein HscB 636227 hscB 1109939 hscB Buchnera aphidicola str. APS (Acyrthosiphon pisum) chaperone protein HscB NP_240402.1 635703 D 107806 CDS NP_240403.1 15617190 1109940 636239..638074 1 NC_002528.1 involved in the maturation of iron-sulfur cluster-containing proteins; chaperone protein HscA 638074 hscA 1109940 hscA Buchnera aphidicola str. APS (Acyrthosiphon pisum) chaperone protein HscA NP_240403.1 636239 D 107806 CDS NP_240404.1 15617191 1109941 638074..638409 1 NC_002528.1 (2Fe-2S) ferredoxin 638409 fdx 1109941 fdx Buchnera aphidicola str. APS (Acyrthosiphon pisum) (2Fe-2S) ferredoxin NP_240404.1 638074 D 107806 CDS NP_240405.1 15617192 1109942 complement(638406..639767) 1 NC_002528.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 639767 engA 1109942 engA Buchnera aphidicola str. APS (Acyrthosiphon pisum) GTP-binding protein EngA NP_240405.1 638406 R 107806 CDS NP_240406.1 15617193 1109943 complement(639860..640441) 1 NC_002528.1 hypothetical protein 640441 yfgM 1109943 yfgM Buchnera aphidicola str. APS (Acyrthosiphon pisum) hypothetical protein NP_240406.1 639860 R 107806 CDS