-- dump date 20140619_013046 -- class Genbank::CDS -- table cds_note -- id note YP_002229165.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_002229167.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002229173.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_002229174.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_002229188.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002229189.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002229194.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002229195.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002229196.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002229197.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002229198.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002229199.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002229200.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002229201.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002229204.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002229205.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_002229206.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002229213.1 catalyzes the transfer of an amino moiety YP_002229224.1 catalyzes the formation of acetaldehyde from ethanolamine YP_002229237.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002229238.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_002229239.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_002229246.1 CDS is possibly extended at the C-terminus, lacking an appropriate translational stop YP_002229275.1 C-terminus is similar to Geobacter sulfurreducens TPR domain protein gsu1547 SWALL:AAR34921 (EMBL:AE017212) (473 aa) fasta scores: E(): 3.1e-69, 47.16% id in 441 aa YP_002229280.1 structural flagella protein; Vibrio contains multiple flagellin genes usually localized into two region on the chromosome, flaAC and flaCEDB in V. cholerae, flaFBA and flaCDE in V. parahemolyticus; FlaA is sigma 54 dependent and essential for motility in V.cholerae but not in V. parahaemolyticus YP_002229281.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002229287.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_002229290.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002229291.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002229292.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002229293.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002229299.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_002229300.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002229302.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002229305.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002229306.1 membrane protein involved in the flagellar export apparatus YP_002229307.1 positive regulator of class III flagellar genes YP_002229309.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002229310.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_002229330.1 Possible alternative translational start site after codon 54 YP_002229345.1 Possible alternative translational start sites YP_002229360.1 C-terminus is similar to Escherichia coli, and Escherichia coli O6 2-hydroxy-3-oxopropionate reductase GarR or b3125 or c3880 SWALL:GARR_ECOLI (SWALL:P23523) (294 aa) fasta scores: E(): 8e-14, 27.66% id in 282 aa, and C-terminus is similar to Xanthomonas campestris dehydrogenase xcc0308 SWALL:Q8PDM7 (EMBL:AE012127) (291 aa) fasta scores: E(): 1.3e-48, 53.1% id in 290 aa YP_002229367.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_002229370.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002229371.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002229372.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_002229373.1 Similar to Burkholderia pseudomallei (strain 1710b) putative outer membrane protein UniProt:Q3JYB8 (EMBL:CP000124) (65 aa) fasta scores: E()=6.9e-06, 45.312% id in 64 aa. Possible gene remnant. Similar to the N-terminal region of Caulobacter crescentus motA/tolQ/exbB proton channel family protein SWALL:Q9A5W1 (EMBL:AE005903) (302 aa) fasta scores: E(): 6.2, 43.13% id in 51 aa YP_002229374.1 CDS is involved in the synthesis of melanin-like pigment which is capable of protecting the organism from in vitro and in vivo sources of oxidative stress YP_002229382.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_002229383.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_002229386.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002229387.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_002229388.1 Modulates Rho-dependent transcription termination YP_002229389.1 binds directly to 23S ribosomal RNA YP_002229390.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_002229391.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002229392.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_002229393.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002229394.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002229396.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_002229397.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002229398.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002229399.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_002229400.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_002229401.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_002229402.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002229403.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002229404.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_002229405.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002229406.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002229407.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002229408.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002229409.1 one of the stabilizing components for the large ribosomal subunit YP_002229410.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002229411.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002229412.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002229413.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002229414.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_002229415.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002229416.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002229417.1 binds 5S rRNA along with protein L5 and L25 YP_002229418.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002229419.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002229420.1 late assembly protein YP_002229421.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002229422.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002229423.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_002229424.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_002229425.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_002229426.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002229427.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002229428.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002229431.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002229432.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002229436.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002229437.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002229439.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002229444.1 C-terminial region is similar to the C-terminus of Francisella novicida PilQ UniProt:Q09WI1 (EMBL:DQ230372 (594 aa) fasta scores: E()=5.8e-35, 32.930% id in 413 aa YP_002229445.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002229446.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002229447.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_002229448.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002229450.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002229451.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002229452.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002229455.1 family C44 cysteine peptidase YP_002229456.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_002229464.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_002229465.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002229476.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002229477.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_002229478.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002229479.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002229480.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_002229482.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_002229483.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002229484.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_002229485.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_002229486.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_002229489.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002229518.1 subfamily M15C metallo peptidase YP_002229523.1 family M1 metallo peptidase YP_002229536.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002229539.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002229540.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002229543.1 subfamily M24B metallo peptidase YP_002229546.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_002229553.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002229556.1 family M61 metallo peptidase YP_002229560.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002229562.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_002229563.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002229564.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_002229565.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_002229567.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002229568.1 protein associated with Co2+ and Mg2+ efflux YP_002229572.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002229573.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_002229575.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002229578.1 C-terminus is similar to the N-terminus of Clostridium tetani conserved protein ctc02236 SWALL:Q891X7 (EMBL:AE015943) (384 aa) fasta scores: E(): 1.2, 30.12% id in 156 aa YP_002229583.1 negatively supercoils closed circular double-stranded DNA YP_002229584.1 binds the polymerase to DNA and acts as a sliding clamp YP_002229585.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002229586.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002229587.1 Possible alternative translational start sites YP_002229589.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002229591.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_002229601.1 involved in the first step of glutathione biosynthesis YP_002229608.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002229613.1 Similar to BCAM1186, 96.488% identity (96.488% ungapped) in 484 aa overlap (1-484:1-484), and BCAM2493, 68.153% identity (68.153% ungapped) in 471 aa overlap (14-484:12-482) YP_002229617.1 family S33 serine peptidase YP_002229624.1 decatenates replicating daughter chromosomes YP_002229627.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002229628.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002229630.1 subfamily M48B metallo peptidase YP_002229643.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002229644.1 functions in MreBCD complex in some organisms YP_002229645.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_002229646.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002229647.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_002229655.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_002229656.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002229658.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002229661.1 heat shock protein involved in degradation of misfolded proteins YP_002229662.1 heat shock protein involved in degradation of misfolded proteins YP_002229666.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002229668.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002229669.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002229670.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002229678.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002229684.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002229685.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002229686.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_002229696.1 Possible gene remnant of two-component regulatory system, sensor kinase protein. Similar to the C-terminal regions of several proteins, for example, Thiobacillus denitrificans (strain ATCC 25259) possible sensor UniProt:Q3SII8 (EMBL:CP000116) (493 aa) fasta scores: E()=1.6e-15, 35.345% id in 232 aa, and to Polaromonas sp. JS666 ATP-binding region UniProt:Q4B3W6 (EMBL:AAFQ02000002) (446 aa) fasta scores: E()=8.1e-15, 34.742% id in 213 aa YP_002229709.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002229719.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_002229724.1 required for the assembly of the flagellar basal body P-ring YP_002229725.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_002229726.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002229727.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_002229728.1 the hook connects flagellar basal body to the flagellar filament YP_002229729.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_002229730.1 makes up the distal portion of the flagellar basal body rod YP_002229731.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Burkholderia thailandensis has 2 copies of this and other flagella genes YP_002229732.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_002229733.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002229734.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002229736.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002229737.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_002229739.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002229761.1 family C26 cysteine peptidase YP_002229771.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_002229773.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002229790.1 Possible alternative translational start site after codon 5 YP_002229792.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_002229808.1 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_002229812.1 no significant database hits YP_002229818.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002229823.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_002229824.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002229825.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_002229826.1 family S9 unassigned serine peptidase YP_002229830.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002229837.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_002229845.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002229851.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_002229852.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_002229861.1 family S9 unassigned serine peptidase YP_002229862.1 family S11 serine peptidase YP_002229865.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002229867.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_002229868.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002229872.1 family T3 threonine peptidase YP_002229879.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002229880.1 involved in the transport of C4-dicarboxylates across the membrane YP_002229890.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_002229896.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_002229899.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002229900.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002229909.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_002229916.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002229927.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_002229928.1 family S33 serine peptidase YP_002229931.1 catalyzes the formation of L-proline from L-ornithine YP_002229944.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002229952.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002229954.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002229955.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002229956.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_002229957.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002229959.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002229961.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002229965.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_002229967.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_002229974.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002229977.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002229981.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_002229983.1 responsible for recognizing base lesions in the genome and initiating base excision DNA repair YP_002229986.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002229992.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002229999.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_002230003.1 subfamily M48B metallo peptidase YP_002230022.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002230023.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_002230027.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002230030.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002230034.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_002230035.1 converts dATP to dAMP and pyrophosphate YP_002230040.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002230041.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002230050.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002230051.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002230056.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_002230057.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002230058.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002230060.1 Transfers the fatty acyl group on membrane lipoproteins YP_002230063.1 contains unknown N-terminal domain/putative metalloprotease C-terminal domain YP_002230065.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002230079.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002230080.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002230084.1 family T3 threonine peptidase YP_002230101.1 Doubtful CDS YP_002230102.1 Possible gene remnant. Similar to the N-terminal region of Staphylococcus lentus plasmid recombination enzyme type 3 Pre UniProt:Q5DU99 (EMBL:AJ888003 (413 aa) fasta scores: E()=1.8e-05, 21.283% id in 343 aa YP_002230107.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_002230108.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002230110.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002230111.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002230116.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002230117.1 subfamily M48B metallo peptidase YP_002230119.1 family S33 serine peptidase YP_002230126.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002230134.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002230135.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002230142.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002230144.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002230145.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002230146.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002230148.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002230149.1 carries the fatty acid chain in fatty acid biosynthesis YP_002230150.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002230152.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002230155.1 subfamily S1B serine peptidase YP_002230157.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002230158.1 subfamily S26A serine peptidase YP_002230159.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002230160.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002230161.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002230162.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002230163.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002230164.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002230166.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002230171.1 Possible alternative translational start site after codon 17 YP_002230175.1 subfamily M24A metallo peptidase YP_002230196.1 family S33 serine peptidase YP_002230207.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_002230210.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_002230211.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_002230212.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002230251.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002230272.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002230278.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002230283.1 C-terminus is similar to C-terminal region of Rhizobium leguminosarum bv. viciae (strain 3841). putative transmembrane protein precursor. UniProt:Q1M4U2 (EMBL:AM236086 (336 aa) fasta scores: E()=8.9e-32, 39.200% id in 250 aa YP_002230284.1 N-terminus is similar to Bradyrhizobium japonicum protein bll4390 SWALL:Q89M03 (EMBL:AP005951) (192 aa) fasta scores: E(): 0.0017, 25.92% id in 162 aa YP_002230285.1 Similar to C-terminus of Chromobacterium violaceum probable transcriptional regulator cv2654 SWALL:Q7NUP3 (EMBL:AE016919) (236 aa) fasta scores: E(): 3.7e-08, 31.48% id in 162 aa YP_002230289.1 Possible alternative translational start sites YP_002230296.1 Similar to the N-terminal region of Streptomyces sp. wa46 salicyl-CoA 5-hydroxylase SdgC UniProt:Q7X281 (EMBL:AB112586 (517 aa) fasta scores: E()=1.7e-41, 34.817% id in 382 aa YP_002230316.1 Similar to C-terminus of Burkholderia cepacia fusaric acid resistance protein FusC SWALL:FUSC_BURCE (SWALL:P24128) (346 aa) fasta scores: E(): 1.5e-34, 36.54% id in 342 aa, and to entire protein of Pseudomonas syringae fusaric acid resistance protein, putative pspto1218 SWALL:Q887R8 (EMBL:AE016860) (728 aa) fasta scores: E(): 4.9e-72, 33.66% id in 695 aa YP_002230331.1 Similar to the C-terminus of Pseudomonas aeruginosa hypothetical protein cp55 SWALL:AAP22547 (EMBL:AY257538) (481 aa) fasta scores: E(): 1.7e-08, 43.18% id in 88 aa YP_002230334.1 no significant database hits YP_002230342.1 C-terminus is similar to Pseudomonas putida hypothetical protein pp2497 SWALL:Q88JZ6 (EMBL:AE016783) (109 aa) fasta scores: E(): 1.2e-08, 41.58% id in 101 aa YP_002230347.1 putative morphinone reductase YP_002230353.1 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002230356.1 catalyzes the formation of putrescine from agmatine YP_002230362.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002230379.1 acyl carrier protein of malonate decarboxylase YP_002230380.1 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A YP_002230382.1 catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein YP_002230392.1 3'-5' exonuclease of DNA polymerase III YP_002230398.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002230400.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002230401.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002230405.1 family M41 metallo peptidase YP_002230407.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002230409.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002230410.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002230411.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002230415.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002230426.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002230432.1 C-terminus is similar to the C-terminus of Serratia marcescens phospholipase phlA SWALL:Q8RKT9 (EMBL:AY091641) (320 aa) fasta scores: E(): 1.5e-08, 32.2% id in 236 aa, and to Xanthomonas campestris phospholipase A1 SWALL:Q8P3M3 (EMBL:AE012526) (729 aa) fasta scores: E(): 2.6e-09, 36.79% id in 212 aa YP_002230451.1 family C44 cysteine peptidase YP_002230459.1 Possible alternative upstream translational start sites YP_002230469.1 catalyzes the formation of 3-(2,3-dihydroxyphenyl)propionate from 3-(3-hydroxyphenyl)propionate YP_002230492.1 Possible gene remnant. Similar to the N-terminal regions of several proteins, for example, similar to CIP 106301) hypothetical protein UniProt:Q2T2T3 (EMBL:CP000085) (169 aa) fasta scores: E()=0.00037, 32.298% id in 161 aa YP_002230493.1 Possible gene remnant. Similar to the C-terminal regions of several proteins, for example, similar to Rhizobium loti (Mesorhizobium loti) MLR4844 protein UniProt:Q98D60 (EMBL:BA000012) (120 aa) fasta scores: E()=2.6e-05, 31.395% id in 86 aa YP_002230501.1 Possible alternative translational start site after codon 4 YP_002230513.1 Similar to the C-terminal region of Homo sapiens (Human) AGPAT1 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha UniProt:Q99943 (EMBL:AL662828) (283 aa) fasta scores: E()=3.4e-06, 30.500% id in 200 aa YP_002230515.1 family S33 serine peptidase YP_002230518.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_002230519.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_002230543.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002230547.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002230579.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002230581.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002230584.1 Partial matches to fusaric acid resistance proteins Burkholderia cepacia; original database entry for these fusaric acid resistance proteins are probably partial gene fragments YP_002230586.1 Partial matches to fusaric acid resistance proteins Burkholderia cepacia; original database entry for these fusaric acid resistance proteins are probably partial gene fragments YP_002230598.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002230609.1 family S33 serine peptidase YP_002230612.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_002230614.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002230615.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_002230616.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_002230617.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002230619.1 Similar to Anabaena sp. putative transposase SWALL:O68472 (EMBL:AF047044) (320 aa) fasta scores: E(): 3.2e-38, 41.8% id in 311 aa YP_002230632.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_002230635.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002230636.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_002230637.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002230638.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002230639.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002230645.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002230646.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002230647.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002230655.1 subfamily A24A aspartic peptidase YP_002230686.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_002230713.1 Codons 90 to 235 are similar to N-terminus to codon 182 of Burkholderia cepacia phage Bcep22 gp4 SWALL:AAQ54940 (EMBL:AY349011) (330 aa) fasta scores: E(): 3.8e-10, 38.99% id in 159 aa YP_002230719.1 N-terminus is similar to Streptomyces avermitilis putative peptidase sav2663 SWALL:Q82JU1 (EMBL:AP005031) (437 aa) fasta scores: E(): 3.5, 36.2% id in 58 aa YP_002230739.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_002230740.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_002230741.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_002230745.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_002230747.1 catalyzes the release of sulfite from alkanesulfonates YP_002230769.1 subfamily M20A metallo peptidase YP_002230771.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_002230775.1 involved in the export of lipooligosaccharides during nodulation YP_002230779.1 Represses a number of genes involved in the response to DNA damage YP_002230799.1 subfamily M23B metallo peptidase YP_002230800.1 MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery YP_002230801.1 MexY; AmrB; involved in resistance to antibiotics; inner membrane protein; belongs to RND (resistance, nodulation, cell division) family of transporters; functions along with MexX and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery YP_002230814.1 RNA polymerase sigma factor involved in the synthesis of the siderophores pyoverdine in Pseudomonas and malleobactin in Burkholderia; also involved in the synthesis of exotoxin and PrpL protease YP_002230818.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002230829.1 subfamily M20D metallo peptidase YP_002230831.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_002230832.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_002230833.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_002230834.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_002230835.1 This TonB-dependent receptor is associated with the cobalamin biosynthesis operon, however it has poor levels of similarity with vitamin B12 transporters associated with cobalamin biosynthesis. Another CDS, BCAM1593, is similar to vitamin B12 transporters. The function of this CDS therefore is unknown and may not be involved with the transport of vitamin B12 YP_002230837.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_002230851.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_002230852.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_002230855.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_002230856.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_002230897.1 family S9 unassigned serine peptidase. N-terminus is similar to Pseudomonas sp. (strain p51) carboxymethylenebutenolidase TcbE UniProt:P27100 (EMBL:M57629 (238 aa) fasta scores: E()=2.2e-26, 40.271% id in 221 aa YP_002230918.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_002230922.1 Weakly similar to the N-terminal region of Magnaporthe grisea Saccharopine dehydrogenase LYS3 UniProt:Q9P4R4 (EMBL:AF144424 (450 aa) fasta scores: E()=0.071, 19.597% id in 347 aa YP_002230937.1 Possible alternative translational start sites YP_002230954.1 member of the periplasmic pilus chaperone family of proteins YP_002230980.1 catalyzes the formation of L-homocysteine from cystathionine YP_002230983.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002230985.1 Possible alternative translational start site after codon 23 YP_002230988.1 catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis YP_002230989.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_002231000.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_002231001.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_002231006.1 Stimulates the elongation of poly(A) tails YP_002231007.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002231010.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_002231011.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_002231014.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002231016.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002231019.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002231022.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002231024.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_002231026.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_002231029.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002231033.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_002231036.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002231037.1 family S33 serine peptidase YP_002231053.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002231054.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_002231055.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_002231061.1 Similar to the N-terminal region of Escherichia coli bifunctional polymyxin resistance arnA protein UniProt:P77398 (EMBL:AP009048 (660 aa) fasta scores: E()=1.3e-41, 42.173% id in 313 aa YP_002231062.1 Similar to the C-terminal region of Escherichia coli bifunctional polymyxin resistance arnA protein UniProt:P77398 (EMBL:AP009048 (660 aa) fasta scores: E()=4.5e-68, 56.250% id in 336 aa YP_002231069.1 unwinds double stranded DNA YP_002231070.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002231071.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002231073.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_002231075.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002231077.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_002231091.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002231092.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002231097.1 family S9 unassigned serine peptidase. Possible alternative translational start sites YP_002231104.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002231106.1 possibly trifunctional YP_002231107.1 activates fatty acids by binding to coenzyme A YP_002231110.1 Involved in cell division; probably involved in intracellular septation YP_002231114.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002231117.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002231121.1 family S16 serine peptidase YP_002231122.1 binds and unfolds substrates as part of the ClpXP protease YP_002231123.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_002231124.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002231127.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002231138.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002231142.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_002231143.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002231145.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_002231151.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002231156.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_002231164.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_002231165.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate YP_002231171.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_002231176.1 N-terminal region is similar to Escherichia coli L-aspartate oxidase NadB UniProt:P10902 (EMBL:ECRBAB) (540 aa) fasta scores: E()=1.7e-13, 24.687% id in 559 aa. Full length CDS is similar to Mycobacterium bovis fumarate reductase flavoprotein subunit FrdA UniProt:P64175 (EMBL:BX248339) (583 aa) fasta scores: E()=3.9e-16, 27.395% id in 595 aa YP_002231188.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002231190.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002231197.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002231200.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002231203.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002231204.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_002231205.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002231206.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002231207.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002231210.1 subfamily M50B metallo peptidase YP_002231211.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002231214.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002231215.1 Catalyzes the phosphorylation of UMP to UDP YP_002231216.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002231217.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002231218.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_002231219.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002231221.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002231226.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate YP_002231227.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002231229.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_002231230.1 involved in methylation of ribosomal protein L3 YP_002231231.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002231235.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002231236.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002231249.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002231253.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002231274.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_002231276.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002231278.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002231282.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_002231288.1 This protein performs the mismatch recognition step during the DNA repair process YP_002231294.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002231296.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002231297.1 subfamily M50B metallo peptidase YP_002231305.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002231306.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002231307.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002231308.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002231316.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 YP_002231317.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_002231321.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002231322.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002231325.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002231332.1 family S11 serine peptidase YP_002231336.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002231339.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_002231340.1 subfamily M3A metallo peptidase YP_002231341.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002231343.1 Similar to Alcaligenes eutrophus putative transposase protein tnpc or phg160 SWALL:AAP85912 (EMBL:AY305378) (517 aa) fasta scores: E(): 1.3e-127, 64.52% id in 513 aa YP_002231344.1 Similar to Alcaligenes eutrophus putative transposition-related protein tnpb or phg159 SWALL:AAP85911 (EMBL:AY305378) (115 aa) fasta scores: E(): 1.5e-31, 68.96% id in 116 aa YP_002231345.1 Similar to Alcaligenes eutrophus putative transposition-related protein tnpa or phg158 SWALL:AAP85910 (EMBL:AY305378) (106 aa) fasta scores: E(): 2.6e-09, 41.12% id in 107 aa YP_002231347.1 subfamily S9A unassigned peptidase YP_002231357.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002231365.1 family C26 cysteine peptidase YP_002231367.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_002231368.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_002231370.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002231372.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002231385.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002231386.1 in Rhizobium meliloti this protein is involved in the synthesis of nodulation factors that are active on the roots of alfalfa; catalyzes formation of activated sulfate intermediate; converts ATP and sulfate to diphosphate and adenylylsulfate and then ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; the activated intermediate is transferred to the nodulation factors by NodH; may interact with NodP and NodQ; similar to the CysD and CysN proteins from EScherichia coli involved in cysteine biosynthesis YP_002231404.1 Identical to Burkholderia cepacia IS1356 transposase SWALL:Q45111 (EMBL:U44828) (419 aa) fasta scores: E(): 1.2e-169, 100% id in 419 aa YP_002231409.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002231414.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_002231427.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_002231428.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002231429.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_002231435.1 Highly similar to Burkholderia cepacia insertion element IS407 hypothetical 10.0 kDa protein SWALL:YI74_BURCE (SWALL:P24580) (87 aa) fasta scores: E(): 1e-31, 98.85% id in 87 aa YP_002231444.1 catalyzes the transfer of an amino moiety YP_002231446.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002231455.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231456.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231457.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002231458.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231459.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231460.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231461.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231462.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002231464.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231465.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231466.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231467.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002231468.1 Catalyzes the transfer of electrons from NADH to quinone YP_002231470.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002231473.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002231478.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002231480.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_002231481.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_002231482.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_002231483.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_002231484.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_002231493.1 Converts glucose to D-glucono-1,5 lactone YP_002231505.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_002231506.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002231507.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002231509.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002231511.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002231513.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002231514.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002231515.1 catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP YP_002231517.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002231518.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002231533.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002231535.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_002231539.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_002231541.1 C-terminus is similar to the C-terminal region of Escherichia coli DNA translocase FtsK UniProt:P46889 (EMBL:AP009048 (1329 aa) fasta scores: E()=8.2e-92, 41.587% id in 1046 aa YP_002231542.1 Possible alternative upstream translational start site YP_002231548.1 Involved in the electron transport chain YP_002231560.1 Possible alternative translational start site after codon 64 YP_002231566.1 molecular chaperone YP_002231578.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002231579.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002231590.1 serine protease inhibitor, inhibits trypsin and other proteases YP_002231602.1 Possible gene remnant; similarity does not extend to the N-terminus and the upstream CDS does not contain a translational stop. Similar to bacteriophage p2 lysozyme K UniProt:P51771 (EMBL:AF063097 (165 aa) fasta scores: E()=8.7e-10, 37.500% id in 144 aa YP_002231605.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002231612.1 component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent YP_002231622.1 CDS is extended at the C-terminus in comparison to orthologues, and the translation extends into an IS elementinserted after codon 395 YP_002231626.1 Similar to the C-terminus of Pseudomonas aeruginosa hypothetical protein Pa0095 pa0095 SWALL:Q9I737 (EMBL:AE004448) (741 aa) fasta scores: E(): 6.3e-65, 43.78% id in 475 aa YP_002231629.1 Similar to the C-terminus of Ralstonia solanacearum hypothetical protein rsc3216 or rs02433 SWALL:Q8XUH2 (EMBL:AL646074) (555 aa) fasta scores: E(): 3e-57, 47.1% id in 363 aa YP_002231630.1 C-terminus is similar to Pseudomonas putida hypothetical protein pp2497 SWALL:Q88JZ6 (EMBL:AE016783) (109 aa) fasta scores: E(): 9.5e-11, 46.07% id in 102 aa YP_002231635.1 no significant database hits YP_002231650.1 family S33 serine peptidase YP_002231657.1 family S33 serine peptidase; Possible gene remnant. Similar to the N-terminal region of Burkholderia xenovorans (strain LB400) putative hydrolase UniProt:Q13RJ2 (EMBL:CP000271 (387 aa) fasta scores: E()=1.1e-51, 59.004% id in 261 aa, and to the full length Streptomyces avermitilis putative hydrolase UniProt:Q82QJ4 (EMBL:BA000030 (266 aa) fasta scores: E()=2.5e-38, 48.047% id in 256 aa YP_002231663.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002231685.1 Possible alternative downstream translational start sites YP_002231692.1 Similar to the N-terminal region of Rhodococcus opacus (Nocardia opaca) 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolacton decarboxylase PcaL UniProt:O67982 (EMBL:AF003947 (400 aa) fasta scores: E()=1.1e-11, 30.739% id in 257 aa; family S33 serine peptidase YP_002231721.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002231726.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002231728.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002231731.1 family S33 serine peptidase YP_002231733.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis YP_002231734.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002231735.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002231742.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002231746.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002231750.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002231755.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002231756.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002231759.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_002231761.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_002231762.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase YP_002231765.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_002231766.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_002231773.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002231775.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002231778.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002231779.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002231783.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_002231785.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002231786.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002231803.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_002231804.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_002231814.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002231816.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002231817.1 required for 70S ribosome assembly YP_002231818.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_002231819.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002231820.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_002231821.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002231825.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002231826.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002231827.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_002231828.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002231829.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_002231830.1 catalyzes the formation of dUMP from dUTP YP_002231834.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002231839.1 Converts isocitrate to alpha ketoglutarate YP_002231842.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002231853.1 catalyzes the formation of 2-dehydropantoate from (R)-pantoate YP_002231860.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002231861.1 Transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_002231863.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002231864.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002231867.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002231869.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_002231870.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002231871.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002231872.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002231875.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002231884.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002231898.1 catalyzes the formation of benzaldehyde from benzoylformate YP_002231904.1 family S12 serine peptidase YP_002231913.1 Converts D-sorbitol to L-sorbose YP_002231918.1 family S9 unassigned serine peptidase YP_002231934.1 family S13 serine peptidase YP_002231938.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002231940.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002231941.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_002231942.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002231943.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002231946.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002231949.1 subfamily M24A metallo peptidase YP_002231953.1 Possible alternative translational start site after codon 17 YP_002231958.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002231960.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002231961.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_002231962.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002231963.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002231964.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002231965.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002231966.1 subfamily S26A serine peptidase YP_002231967.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002231969.1 subfamily S1B serine peptidase YP_002231972.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002231974.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_002231975.1 carries the fatty acid chain in fatty acid biosynthesis YP_002231976.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002231978.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002231979.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002231980.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_002231982.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002231989.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_002231990.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002231998.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002232008.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002232012.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_002232015.1 CDS is associated with trimethoprim resistance YP_002232018.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002232019.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002232020.1 subfamily M48A metallo peptidase YP_002232021.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002232025.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002232026.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002232027.1 Essential for efficient processing of 16S rRNA YP_002232028.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002232033.1 catalyzes the oxidative deamination of D-amino acids YP_002232038.1 part of the metNIQ transport system for methionine YP_002232039.1 family S33 serine peptidase YP_002232042.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_002232045.1 Similar to the N-terminal region of Salmonella typhimurium bifunctional protein hldE [Includes: D-beta-D-heptose 7-phosphate kinase; D-beta-D heptose 1-phosphate adenosyltransferase] UniProt:Q7CPR9 (EMBL:AE008847 (477 aa) fasta scores: E()=1.2e-43, 51.634% id in 306 aa YP_002232049.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_002232050.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002232051.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002232052.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002232055.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002232057.1 negatively supercoils closed circular double-stranded DNA YP_002232059.1 Involved in ubiquinone biosynthesis YP_002232064.1 Similar to C-terminus of Ralstonia solanacearum hypothetical protein rsc1870 or rs06006 SWALL:Q8XY93 (EMBL:AL646067) (413 aa) fasta scores: E(): 1.4e-11, 31.72% id in 249 aa YP_002232079.1 Similar to N-terminus of Shewanella oneidensis hypothetical protein so4261 SWALL:Q8E9L0 (EMBL:AE015859) (216 aa) fasta scores: E(): 5.9e-05, 56.81% id in 44 aa YP_002232083.1 no significant database hits YP_002232096.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002232097.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002232099.1 catalyzes the formation of inosine from adenosine YP_002232100.1 Catalyzes the deamination of guanine YP_002232103.1 family M1 metallo peptidase YP_002232104.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_002232114.1 catalyzes the interconversion of chorismate to prephenate YP_002232119.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_002232121.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002232122.1 Essential for recycling GMP and indirectly, cGMP YP_002232124.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002232125.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002232126.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002232135.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002232137.1 blocks the formation of polar Z-ring septums YP_002232140.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_002232143.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002232152.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002232154.1 glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002232159.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002232161.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002232163.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_002232164.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_002232165.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002232174.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002232179.1 catalyzes the formation of propanoyl-CoA from methylmalonyl-CoA YP_002232201.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002232202.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002232205.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002232215.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_002232216.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_002232217.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_002232221.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002232236.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002232245.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_002232247.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002232248.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002232249.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_002232250.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002232255.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_002232256.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002232263.1 Similar to codons 738 to 1690 of Rhizobium loti hypothetical glycine-rich protein Mlr0585 mlr0585 SWALL:Q98MG8 (EMBL:AP002995) (2147 aa) fasta scores: E(): 1e-32, 33.91% id in 979 aa YP_002232293.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_002232306.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002232312.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002232330.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002232334.1 Highly similar to Burkholderia cepacia insertion element IS407 hypothetical 10.0 kDa protein SWALL:YI74_BURCE (SWALL:P24580) (87 aa) fasta scores: E(): 1e-31, 98.85% id in 87 aa YP_002232335.1 C-terminus is similar to Helicobacter pylori J99 putative jhp0052 SWALL:Q9ZN08 (EMBL:AE001444) (327 aa) fasta scores: E(): 6.6e-09, 28.71% id in 310 aa YP_002232337.1 Possible alternative translational start site. C-terminal region is similar to Burkholderia phymatum stm815 fkbH like protein UniProt:A0FXR6 (EMBL:AAUG01000008 (623 aa) fasta scores: E()=1.1e-54, 37.500% id in 592 aa YP_002232348.1 C-terminus is similar to Streptococcus thermophilus EpsH or Eps1I SWALL:Q93DZ7 (EMBL:AF373595) (316 aa) fasta scores: E(): 1.4e-19, 33.2% id in 250 aa, and C-terminus is similar to Campylobacter jejuni putative sugar transferase cj1434C SWALL:Q9PMM3 (EMBL:AL139078) (445 aa) fasta scores: E(): 2.8e-21, 31.54% id in 279 aa YP_002232357.1 Similar to Rhizobium meliloti transposase for insertion sequence element isrm3 SWALL:TRA3_RHIME (SWALL:P80011) (400 aa) fasta scores: E(): 1.7e-91, 58.5% id in 400 aa YP_002232359.1 Similar to Ralstonia solanacearum isrso11- transposase OrfA protein SWALL:Q8XG34 (EMBL:AL646073) (177 aa) fasta scores: E(): 9.2e-31, 55.68% id in 176 aa YP_002232361.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002232362.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002232365.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002232371.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_002232373.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_002232374.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002232376.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002232378.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002232379.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_002232380.1 catalyzes the phosphorylation of NAD to NADP YP_002232382.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002232386.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_002232396.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002232400.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_002232403.1 Similar to BCAM2107, 76.119% identity (77.166% ungapped) in 737 aa overlap (1-728:1-736) YP_002232405.1 catalyzes branch migration in Holliday junction intermediates YP_002232406.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002232408.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002232409.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_002232410.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_002232432.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002232435.1 subfamily M24B metallo peptidase YP_002232439.1 involved in de novo purine biosynthesis YP_002232440.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002232441.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002232442.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002232446.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002232447.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002232448.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_002232449.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_002232450.1 forms a direct contact with the tRNA during translation YP_002232451.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002232455.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002232463.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002232469.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002232472.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002232473.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002232475.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_002232478.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_002232481.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_002232482.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate YP_002232483.1 involved in the transport of C4-dicarboxylates across the membrane YP_002232485.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_002232491.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_002232492.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002232494.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_002232497.1 NAD-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; does not decarboxylate oxaloacetate YP_002232498.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002232502.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_002232505.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002232506.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002232509.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_002232514.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002232515.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002232521.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002232522.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002232523.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_002232524.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002232530.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002232531.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002232536.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_002232538.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002232539.1 hydrolyzes diadenosine polyphosphate YP_002232541.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002232542.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002232543.1 involved in the peptidyltransferase reaction during translation YP_002232547.1 Possible alternative translational start after codon 4 YP_002232549.1 subfamily A24A aspartic peptidase YP_002232550.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002232554.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_002232555.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002232557.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002232559.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_002232562.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002232563.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002232564.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002232566.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002232567.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002232569.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002232573.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002232576.1 activates fatty acids by binding to coenzyme A YP_002232586.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002232588.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002232604.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002232605.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_002232606.1 Internal region is similar to Escherichia coli flagellar protein FliO UniProt:P22586 (EMBL:AP009048 (121 aa) fasta scores: E()=9.1e-07, 40.816% id in 98 aa YP_002232608.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002232609.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002232632.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001989036.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002232636.1 Similar to Ralstonia solanacearum putative partitioning protein parB SWALL:Q8XTV0 (EMBL:AL646076) (334 aa) fasta scores: E(): 4.7e-19, 28.71% id in 310 aa; homology does not extend to the N terminus YP_002232638.1 no significant database hits YP_002232639.1 Contains coiled-coiled domains, residues 112 to 296 YP_002232643.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002232644.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_002232645.1 no significant database hits YP_002232646.1 Poor database matches. C-terminal region is similar to Chromobacterium violaceum hypothetical protein SWALL:Q7NWH5 (EMBL:AE016917) (161 aa) fasta scores: E(): 8.3e-13, 35.06% id in 154 aa YP_002232651.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_002232655.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_002232656.1 converts acetoacetate to acetone and carbon dioxide YP_002232658.1 no significant database hits YP_002232660.1 Similar to Rhodopseudomonas palustris transcriptional regulator, padr family SWALL:Q6NB15 (EMBL:BX572596) (196 aa) fasta scores: E(): 1.3e-16, 42.07% id in 183 aa; homology does not extend to the N terminus YP_002232661.1 no significant database matches YP_002232662.1 no significant database matches YP_002232665.1 Similar to Streptomyces galilaeus AknN SWALL:Q9L4V1 (EMBL:AF264025) (662 aa) fasta scores: E(): 1.3e-37, 35.36% id in 673 aa; homology does not extend to termini YP_002232672.1 Similar to Pseudomonas oleovorans alcohol dehydrogenase [acceptor] alkJ SWALL:ALKJ_PSEOL (SWALL:Q00593) (558 aa) fasta scores: E(): 1.4e-76, 41.69% id in 530 aa; contains C terminal 30 amino acid truncation YP_002232674.1 Similar to Erwinia carotovora hypothetical protein SWALL:Q6D2K7 (EMBL:BX950851) (253 aa) fasta scores: E(): 2.1e-21, 37.61% id in 218 aa YP_002232676.1 Similar to Ralstonia solanacearum putative vgr-related protein rs03020 SWALL:Q8XTK5 (EMBL:AL646076) (885 aa) fasta scores: E(): 6.7e-86, 51.59% id in 814 aa; homology does not extend to C terminus YP_002232678.1 no significant database matches YP_002232679.1 Weakly similar to Chromobacterium violaceum hypothetical protein SWALL:Q7P249 (EMBL:AE016910) (512 aa) fasta scores: E(): 2.5e-11, 30.85% id in 512 aa YP_002232681.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002232682.1 Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri fumarate and nitrate reduction regulatory protein fnR SWALL:FNR_ECOLI (SWALL:P03019) (250 aa) fasta scores: E(): 4.2e-35, 42.92% id in 226 aa; homology does not extend to N terminus YP_002232688.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_002232690.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_002232693.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_002232694.1 family S33 serine peptidase YP_002232699.1 Similar to Streptomyces avermitilis hypothetical protein SWALL:Q82B80 (EMBL:BA000030) (654 aa) fasta scores: E(): 3.7e-59, 35.8% id in 648 aa; homology does not extend to far C terminus YP_002232702.1 Similar to Streptomyces parvulus hypothetical protein BorL SWALL:Q70HZ3 (EMBL:AJ580915) (556 aa) fasta scores: E(): 1.8e-57, 35.79% id in 528 aa; homology does not extend to N terminus YP_002232703.1 Similar to Streptomyces parvulus hypothetical protein BorF borF SWALL:Q70I05 (EMBL:AJ580915) (272 aa) fasta scores: E(): 8.7e-27, 35.79% id in 257 aa; homology does not extend to the N terminus YP_002232705.1 no significant database matches YP_002232706.1 Central 170 amino acids similar to Caulobacter crescentus hypothetical protein cc1419 SWALL:Q9A8D5 (EMBL:AE005816) (336 aa) fasta scores: E(): 2.3e-15, 35.59% id in 177 aa YP_002232710.1 Similar to Escherichia coli 3- mhpA SWALL:MHPA_ECOLI (SWALL:P77397) (554 aa) fasta scores: E(): 3.7e-45, 32.94% id in 510 aa; homology does not extend to far N and C termini YP_002232711.1 Similar to Burkholderia cepacia trihydroxytoluene oxygenase dntD SWALL:O87474 (EMBL:AF076848) (315 aa) fasta scores: E(): 5.8e-37, 39.33% id in 300 aa; contains extensions at the N and C termini YP_002232723.1 no significant database matches YP_002232726.1 Poor database matches to the full length CDS. N-terminal region is similar to Rhizobium meliloti heavy metal dependent transcription regulator 2 HmrR2 SWALL:HMR2_RHIME (SWALL:P58379) (147 aa) fasta scores: E(): 0.033, 31.34% id in 134 aa YP_002232729.1 Similar to Escherichia coli sn-glycerol-3-phosphate transport ATP-binding protein UgpC ugpC SWALL:UGPC_ECOLI (SWALL:P10907) (356 aa) fasta scores: E(): 1.8e-56, 48.35% id in 364 aa; contains 30 amino acid C terminal extension YP_002232732.1 Similar to Rhizobium loti sugar ABC transporter permease protein SWALL:Q98D12 (EMBL:BA000012) (290 aa) fasta scores: E(): 6.6e-68, 63.38% id in 284 aa; contains 27 amino acid N terminal extension YP_002232739.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002232745.1 Similar to the N-terminal region of Bos taurus amine oxidase [flavin-containing] A MAOA SWALL:AOFA_BOVIN (SWALL:P21398) (527 aa) fasta scores: E(): 1.4e-26, 31.33% id in 466 aa YP_002232746.1 C-terminal region is similar to Chromatium vinosum cytochrome subunit of sulfide dehydrogenase precursor FccA SWALL:CYSD_CHRVI (SWALL:Q06529) (199 aa) fasta scores: E(): 7.1e-06, 26.4% id in 178 aa YP_002232756.1 C-terminus is similar to the N-terminal region of Homo sapiens amine oxidase [flavin-containing] B MAOB SWALL:AOFB_HUMAN (SWALL:P27338) (519 aa) fasta scores: E(): 4.1e-32, 33.54% id in 462 aa YP_002232760.1 Similar to the N-terminal region of Rattus norvegicus nonspecific lipid-transfer protein, mitochondrial precursor SCP2 SWALL:NLTP_RAT (SWALL:P11915) (547 aa) fasta scores: E(): 4.8e-30, 36.54% id in 405 aa YP_002232762.1 Poor database matches YP_002232764.1 Hsp31 stabilizes early unfolding protein intermediates under severe heat stress YP_002232770.1 Similar to the N-terminal region Escherichia coli, and Escherichia coli O6 osmotically inducible protein Y precursor osmY SWALL:OSMY_ECOLI (SWALL:P27291) (201 aa) fasta scores: E(): 0.71, 28.57% id in 119 aa, and to the full length Xanthomonas campestris hypothetical protein XCC3437 SWALL:Q8P5A4 (EMBL:AE012463) (120 aa) fasta scores: E(): 5.5, 30.68% id in 88 aa YP_002232779.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_002232782.1 Similar to Ralstonia solanacearum probable phospholipase protein rs03737 SWALL:Q8XS51 (EMBL:AL646079) (652 aa) fasta scores: E(): 3.5e-85, 50.36% id in 691 aa. C-terminus is weakly similar to the C-terminal region of Arabidopsis thaliana phospholipase D beta 1 PLDbeta1 SWALL:PDB1_ARATH (SWALL:P93733) (967 aa) fasta scores: E(): 0.06, 24.01% id in 483 aa YP_002232785.1 transports degraded pectin products into the bacterial cell YP_002232786.1 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate YP_002232787.1 CDS is extending at the N-terminus in comparison to orthologues YP_002232788.1 Lack of similarity at the N-terminus in comparison to other proteins YP_002232805.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_002232807.1 malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate YP_002232813.1 subfamily M23B metallo peptidase. Weakly similar to Rhizobium loti MLR3423 protein SWALL:Q98GA2 (EMBL:AP003001) (476 aa) fasta scores: E(): 1.3e-18, 29.73% id in 454 aa. C-terminus is similar to the C-terminal region of Bordetella parapertussis hypothetical protein SWALL:Q7W3Z7 (EMBL:BX640435) (471 aa) fasta scores: E(): 9.1e-27, 39.39% id in 264 aa YP_002232816.1 Similar to the C-terminal region of Bordetella parapertussis autotransporter SWALL:Q7WC79 (EMBL:BX640424) (1616 aa) fasta scores: E(): 7.3e-42, 33.64% id in 1165 aa YP_002232817.1 No significant database matches to the full length CDS. C-terminus is similar to Chromobacterium violaceum hypothetical protein SWALL:Q7NX84 (EMBL:AE016916) (114 aa) fasta scores: E(): 3.7e-18, 56.14% id in 114 aa, and to the C-terminal region of Photorhabdus luminescens hypothetical protein SWALL:Q937N3 (EMBL:AF346497) (320 aa) fasta scores: E(): 4.5e-08, 33.51% id in 182 aa YP_002232818.1 N-terminal region is similar to Photorhabdus luminescens hypothetical membrane protein SWALL:Q7MZP1 (EMBL:BX571873) (139 aa) fasta scores: E(): 2.3e-18, 56.06% id in 132 aa. C-terminal region is similar to Chromobacterium violaceum hypothetical protein SWALL:Q7NX84 (EMBL:AE016916) (114 aa) fasta scores: E(): 1.4e-15, 51.75% id in 114 aa. Full length CDS is similar to the C-terminal region of Photorhabdus luminescens photopexin B PpxB SWALL:Q7MZN8 (EMBL:BX571873) (340 aa) fasta scores: E(): 2e-06, 28.62% id in 276 aa YP_002232821.1 Similar to Ralstonia solanacearum transcriptional activator protein SolR or rsc3287 or rs02516 SWALL:SLR1_RALSO (SWALL:P58590) (236 aa) fasta scores: E(): 7.1e-29, 38.79% id in 232 aa, and to Burkholderia stabilis N-acyl homoserine lactone transcriptional regulator cepR SWALL:Q93PF6 (EMBL:AF333005) (239 aa) fasta scores: E(): 6e-26, 38.46% id in 234 aa YP_002232826.1 homology extends only to N terminus of protein YP_002232828.1 homology does not extend to N terminus YP_002232839.1 Similar to Rhizobium meliloti (Sinorhizobium meliloti) putative glycosyltransferase. UniProt:Q92QS8 (414 aa) fasta scores: E()=1.1e-31, 35.092% id in 379 aa; homology does not extend to far N and C termini YP_002232842.1 Similar to Ralstonia solanacearum (Pseudomonas solanacearum) EPS I polysaccharide export outer membrane protein EpsA precursor UniProt:EPA2_RALSO (377 aa) fasta scores: E()=4.9e-43, 43.490% id in 361 aa; homology does not extend to N terminus YP_002232843.1 Similar to Escherichia coli WcaJ putative colanic biosynthesis UDP-glucose lipid carrier transferase UniProt:WCAJ_ECOLI (EMBL:ECD842) (464 aa) fasta scores: E()=2.8e-47, 39.348% id in 399 aa; homology does not extend to the N terminus YP_002232844.1 Similar to central region of Bacillus cereus (strain ATCC 14579/DSM 31) hypothetical protein. UniProt:Q81DW8 (384 aa) fasta scores: E()=2.9e-18, 30.403% id in 273 aa YP_002232845.1 Similar to Ralstonia solanacearum (Pseudomonas solanacearum) rs00434 hypothetical protein rsc3164. UniProt:Q8XUM3 (387 aa) fasta scores: E()=4.8e-19, 35.455% id in 330 aa; homology does not extend to N terminus YP_002232846.1 N terminus is similar to N terminus of Brucella melitensis chloride channel protein. UniProt:Q8YFS5 (555 aa) fasta scores: E()=4.9, 32.877% id in 73 aa YP_002232847.1 Similar to C terminus of Rhizobium loti (Mesorhizobium loti) mll0582 protein. UniProt:Q98MH1 (931 aa) fasta scores: E()=1.7e-15, 27.925% id in 265 aa YP_002232850.1 Similar to Yersinia pestis hypothetical protein UniProt:Q8CLT6 (74 aa) fasta scores: E()=1.1, 38.596% id in 57 aa; homology does not extend to N- and C-termini YP_002232851.1 C terminus is similar to C terminus of Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides) dors dmso/tmao-sensor kinase. UniProt:O30740 (815 aa) fasta scores: E()=1.9e-36, 33.663% id in 505 aa YP_002232852.1 Contains many Hep_Hag repeats and haemagglutinin motifs YP_002232853.1 Similar to Bordetella avium ompa outer membrane protein A precursor. UniProt:OMPA_BORAV (EMBL:A45275) (194 aa) fasta scores: E()=2.6e-08, 39.552% id in 134 aa; homology does not extend to the N terminus YP_002232856.1 Contains many Hep_Hag repeats and haemagglutinin motif YP_002232857.1 contains many Hep_Hag repeats and haemagglutinin motifs YP_002232858.1 C terminus similar to C terminus of Bordetella pertussis bvgs virulence sensor protein bvgs precursor. UniProt:BVGS_BORPE (EMBL:A40185) (1238 aa) fasta scores: E()=1.7e-42, 33.185% id in 672 aa YP_002232859.1 Similar to Bordetella parapertussis probable two-component response regulator. UniProt:Q7W2G4 (244 aa) fasta scores: E()=9e-18, 29.911% id in 224 aa; contains 50 amino acid N terminal extension YP_002232860.1 C terminus is similar to C terminus Chromobacterium violaceum probable two-component sensor, UniProt:Q7NVL8 (417 aa) fasta scores: E()=3.3e-20, 36.290% id in 248 aa YP_002232863.1 C-terminus similar to Chlamydomonas reinhardtii cgcr-4 product (fragment). UniProt:Q39598 (265 aa) fasta scores: E()=0.00014, 35.616% id in 219 aa YP_002232869.1 Similar to Xanthomonas campestris (pv. campestris) Kch ion transporter. UniProt:Q8P5Q3 (290 aa) fasta scores: E()=6.9e-43, 47.547% id in 265 aa; homology does not extend to N terminus YP_002232871.1 Similar to C-terminus of Ralstonia solanacearum (Pseudomonas solanacearum) rs06006 hypothetical protein rsc1870. UniProt:Q8XY93 (413 aa) fasta scores: E()=5.1e-11, 41.447% id in 152 aa YP_002232872.1 Similar to Ralstonia solanacearum autoinducer synthesis protein SolI or rsc3286 or rs02515 SWALL:SLI1_RALSO (SWALL:P58584) (204 aa) fasta scores: E(): 1.1e-18, 40.21% id in 184 aa, and to Burkholderia cepacia AHL synthase CepI SWALL:Q9AM52 (EMBL:AF330017) (202 aa) fasta scores: E(): 1.3e-18, 39.22% id in 181 aa. Contributes to virulence of B. cenocepacia. The CciI autoinducer synthase produces C6-HSL and smaller amounts of C8-HSL YP_002232873.1 Similar to Pseudomonas aeruginosa regulatory protein RhlR or LasM or VsmR or pa3477 SWALL:RHLR_PSEAE (SWALL:P54292) (241 aa) fasta scores: E(): 2.6e-11, 29.83% id in 238 aa. C-terminus similar to the C-terminal region of Vibrio anguillarum transcriptional activator protein VanR SWALL:VANR_VIBAN (SWALL:P74946) (240 aa) fasta scores: E(): 6.1e-14, 30.31% id in 188 aa YP_002232885.1 Similar to Geobacillus kaustophilus acyl-CoA dehydrogenase. UniProt:Q5KW71_GEOKA (EMBL:BA000043) (404 aa) fasta scores: E()=1.5e-40, 39.578% id in 379 aa; homology does not extend to far N and C termini YP_002232887.1 Similar to Bacillus licheniformis (strain DSM 13/ATCC 14580) hypothetical protein. UniProt:Q65M07_BACLD (EMBL:AE017333) (65 aa) fasta scores: E()=0.058, 40.351% id in 57 aa, and to N terminus of Bacteriophage phi-105 immunity repressor protein. UniProt:RPC_BPPH1 (EMBL:A93579) (144 aa) fasta scores: E()=0.11, 31.250% id in 80 aa YP_002232894.1 no significant database matches YP_002232897.1 Contributes to virulence of B. cenocepacia YP_002232912.1 Similar to Prochlorococcus marinus subsp. pastoris (strain CCMP 1378/MED4) putative dape gene and orf2. UniProt:Q7V091 (294 aa) fasta scores: E()=3.8e-41, 44.444% id in 252 aa; homology does not extend to N terminus YP_002232918.1 Similar to Xanthomonas campestris (pv. campestris) hrpx hrpx related protein. UniProt:Q8P9A6 (697 aa) fasta scores: E()=7.1e-23, 27.436% id in 667 aa, and C terminus is similar to Ralstonia solanacearum (Pseudomonas solanacearum) rs00623 probable transmembrane two component system sensor kinase transcription regulator protein. UniProt:Q8Y2Z0 (458 aa) fasta scores: E()=8.9e-64, 49.438% id in 445 aa YP_002232926.1 Similar to Methylobacterium extorquens PhaC poly(3-hydroxyalkanoate) polymerase UniProt:PHAC_METEX (EMBL:MEPHAC) (605 aa) fasta scores: E()=3.2e-68, 39.920% id in 501 aa; homology does not extend to N terminus YP_002232935.1 no significant database matches YP_002232937.1 Similar to Geobacter sulfurreducens hypothetical protein. UniProt:Q747B6 (165 aa) fasta scores: E()=1.5e-09, 31.429% id in 140 aa; homology does not extend to the N terminus YP_002232938.1 family M41 metallo peptidase. Similar to Shigella flexneri cell division protein FtsH . UniProt:FTSH_ECOLI (EMBL:AE015333) (644 aa) fasta scores: E()=4.1e-87, 51.005% id in 547 aa; homology does not extend to N-terminus or far C-terminus YP_002232939.1 class I; catalyzes the formation of deoxyribonucleotides from their corresponding ribonucleotides YP_002232943.1 Similar to N-terminus of Acinetobacter sp. (strain ADP1) hypothetical protein. UniProt:Q6FB16 (181 aa) fasta scores: E()=5.6e-14, 41.818% id in 110 aa YP_002232947.1 Similar to central regions of Synechocystis sp. (strain PCC 6803) ziaa zinc-transporting atpase, (zn(ii)-translocating p-type atpase). UniProt:ATZN_SYNY3 (EMBL:SSSLRG) (721 aa) fasta scores: E()=2.5e-39, 30.237% id in 549 aa, and to Chromobacterium violaceum probable cation transport p-type atpase. UniProt:Q7NUF1 (721 aa) fasta scores: E()=2.5e-113, 51.573% id in 731 aa YP_002232950.1 Similar to C-terminus of Vibrio cholerae hypothetical protein vca0893. UniProt:Q9KL55 (169 aa) fasta scores: E()=0.00016, 32.381% id in 105 aa YP_002232953.1 Similar to Brucella abortus VirB1 UniProt:Q9KIT0 (238 aa) fasta scores: E()=3e-27, 44.749% id in 219 aa; truncated by C terminal 23 amino acids; type IV secretion system YP_002232954.1 Similar to Brucella melitensis attachment mediating protein VirB2 homolog. UniProt:Q9RPY3 (105 aa) fasta scores: E()=5.1e-06, 43.478% id in 69 aa; homology does not extend to the N terminus YP_002232962.1 Similar to Rhizobium meliloti (Sinorhizobium meliloti) virb10 transmembrane type IV secretion protein. UniProt:Q92Z02 (390 aa) fasta scores: E()=8.6e-28, 37.709% id in 358 aa; homology does not extend to the N terminus YP_002232963.1 homology does not extend to far C-terminus YP_002232967.1 Similar to Bordetella bronchiseptica (Alcaligenes bronchisepticus) vird2 plasmid-related protein. UniProt:Q7WQ38 (331 aa) fasta scores: E()=1.1e-41, 43.607% id in 305 aa; homology does not extend to far C terminus YP_002232971.1 no significant database hits YP_002232979.1 Similar to Ralstonia solanacearum (Pseudomonas solanacearum) rs04417 probable composite atp-binding transmembrane abc transporter protein. UniProt:Q8Y258 (592 aa) fasta scores: E()=1.1e-40, 31.016% id in 561 aa; contains 32 amino acid C terminal truncation YP_002232985.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002232986.1 Similar to Ralstonia solanacearum (Pseudomonas solanacearum) rs04533 hypothetical protein rsc2672. UniProt:Q8XW03 (159 aa) fasta scores: E()=6.5e-13, 35.294% id in 153 aa; contains extra 26 amino acids on N terminus YP_002232987.1 Similar to Bacteroides thetaiotaomicron hypothetical protein. UniProt:Q8A0C8 (717 aa) fasta scores: E()=6.8e-40, 34.505% id in 768 aa; higher similarity at C terminus than N terminus YP_002232994.1 no significant database hits YP_002232995.1 Similar to Escherichia coli O6 hypothetical protein YebB UniProt:Q8FGR2_ECOL6 (EMBL:AE016761) (224 aa) fasta scores: E()=3.7e-29, 43.548% id in 186 aa; homology does not extend to the N terminus. YP_002233003.1 Similar to Chromobacterium violaceum probable sensor histidine kinase/response regulator. UniProt:Q7NVX8 (734 aa) fasta scores: E()=7.7e-24, 26.592% id in 628 aa; truncated by 100+ amino acids at C terminus YP_002233005.1 Similar to Chromobacterium violaceum hypothetical protein. UniProt:Q7NTP6 (287 aa) fasta scores: E()=8e-14, 29.555% id in 247 aa; homology does not extend to the C terminus YP_002233008.1 no significant database hits YP_002233009.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate YP_002233011.1 catalyzes the formation of acetate from pyruvate YP_002233019.1 Similar to middle section of Oryza sativa (japonica cultivar-group) p0640e12.104 hypothetical protein p0640e12.104. UniProt:Q84NP0 (413 aa) fasta scores: E()=1.5, 32.203% id in 118 aa YP_002233023.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_002233025.1 catalyzes the reaction of cyanate and bicarbonate to produce ammonia and carbon dioxide YP_002233032.1 Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) PlcN non-hemolytic phospholipase C precursor UniProt:Q9RGS8 (EMBL:AF107252) (700 aa) fasta scores: E()=3.1e-63, 46.788% id in 716 aa; homology does not extend to the far C-terminus YP_002233033.1 no significant database matches; doubtful CDS, but contains significant hydrophobic feature YP_002233039.1 Low level of similarity to Nitrosomonas europaea hypothetical protein. UniProt:Q82UF2 (439 aa) fasta scores: E()=1.2e-14, 25.607% id in 453 aa YP_002233045.1 N-terminus is similar to Streptomyces avermitilis hypothetical protein. UniProt:Q82K18 (511 aa) fasta scores: E()=3.3e-43, 44.631% id in 298 aa YP_002233052.1 family C45 cysteine peptidase YP_002233053.1 Contains 30 amino acid N-terminal extension in comparison to some proteins YP_002233060.1 contains 90 amino acid C terminal extension YP_002233081.1 no significant database matches YP_002233082.1 Contains additional C terminal DUF domain YP_002233097.1 no significant database matches YP_002233098.1 no significant database hits YP_002233099.1 no significant database hits YP_002233100.1 no significant database hits YP_002233101.1 family C44 cysteine peptidase YP_002233103.1 also called ketopantoate hydroxymethyltransferase YP_002233107.1 homology does not extend to far N terminus YP_002233117.1 no significant database hits YP_002233119.1 no significant database hits YP_002233134.1 family S12 serine peptidase YP_002233138.1 homology does not extend to far N terminus; Similar to Saccharomyces cerevisiae (Baker's yeast) gtt2 glutathione s-transferase ii, (gst-ii). UniProt:Q12390 (EMBL:AY557940) (233 aa) fasta scores: E()=2.1e-62, 77.670% id in 206 aa; homology does not extend to N terminal 15 amino acids YP_002233142.1 catalyzes the oxidative decarboxylation of malate to form pyruvate YP_002233161.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002233169.1 no significant database matches YP_002233170.1 no significant database matches YP_002233172.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; the rhizobia and high GC gram-positive bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the R. leguminosarum protein in this cluster is transcribed under anaerobic conditions and is not necessary for growth YP_002233173.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002233203.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_002233204.1 regulator of pathogenicity factor RpfF; involved in synthesis of a diffusible signal factor involved in the regulation of extracellular enzymes YP_002233220.1 Similar to Bacillus subtilis GbsB alcohol dehydrogenase, UniProt:P71017 (EMBL:BSU47861) (402 aa) fasta scores: E()=2.3e-19, 33.555% id in 301 aa; similarity does not extend to C terminal 90 amino acids YP_002233228.1 catalyzes the formation of L-proline from L-ornithine YP_002233238.1 Similar to Erwinia carotovora subsp. atroseptica (Pectobacterium atrosepticum) hypothetical protein. UniProt:Q6D9K2 (163 aa) fasta scores: E()=3.1e-19, 37.908% id in 153 aa; contains 30 amino acid C terminal extension YP_002233240.1 no significant database matches YP_002233254.1 Similar to Pseudomonas putida alkj alcohol dehydrogenase [acceptor]. UniProt:Q9WWW2 (EMBL:PPU233397) (552 aa) fasta scores: E()=4.6e-89, 47.159% id in 528 aa; homology does not extend to C terminal 40 amino acids YP_002233280.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_002233281.1 Similar to Escherichia coli shia shikimate transporter. UniProt:P76350 (EMBL:ECD837) (438 aa) fasta scores: E()=9.9e-54, 39.192% id in 421 aa; homology does not cover N terminal 20 amino acids YP_002233289.1 family S12 serine peptidase YP_002233308.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_002233313.1 Internal region is similar to an internal region of Homo sapiens (Human) RRBP1 ribosome-binding protein 1 UniProt:Q9P2E9 (1410 aa) fasta scores: E()=0.0023, 23.055% id in 707 aa YP_002233321.1 family S33 serine peptidase YP_002233322.1 Similar to Caulobacter crescentus monooxygenase, flavin-binding family. UniProt:Q9A588 (498 aa) fasta scores: E()=5.2e-119, 61.245% id in 498 aa; contains 20 amino acid N terminal extension YP_002233333.1 family M35 metallo peptidase YP_002233335.1 Similar to Alcaligenes eutrophus (Ralstonia eutropha) cobalt-zinc-cadmium resistance protein CzcB (cation efflux system protein czcb). UniProt:P13510 (EMBL:AECZCDRS) (520 aa) fasta scores: E()=8.5e-71, 51.131% id in 442 aa; homology does not extend to N terminus YP_002233369.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002233375.1 family S33 serine peptidase YP_002233381.1 Similar to central section of Burkholderia pseudomallei (Pseudomonas pseudomallei) hypothetical protein. UniProt:Q63VD8 (EMBL:BX571965) (148 aa) fasta scores: E()=8.1e-12, 48.673% id in 113 aa YP_002233387.1 Possible alternative upstream translational start sites YP_002233393.1 Similar to Bradyrhizobium japonicum bll5622 protein. UniProt:Q89IL2 (EMBL:BA000040) (175 aa) fasta scores: E()=1.1e-14, 41.463% id in 123 aa; contains 45 amino acid N terminus truncation YP_002233395.1 no significant database matches YP_002233402.1 central section has homology to MCP2_SALTY P02941 Methyl-accepting chemotaxis protein YP_002233404.1 no significant database matches YP_002233408.1 Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) hypothetical protein. UniProt:Q63MP8 (EMBL:BX571966) (208 aa) fasta scores: E()=6e-41, 66.667% id in 144 aa; homology does not cover N terminal 50 amino acids YP_002233422.1 Similar to Homo sapiens (Human) nqo2 ribosyldihydronicotinamide dehydrogenase [quinone], (nrh dehydrogenase [quinone] 2) (quinone reductase 2) (qr2) (nrh:quinone oxidoreductase 2). UniProt:P16083 (EMBL:AB050248) (230 aa) fasta scores: E()=4.2e-29, 40.000% id in 225 aa; homology does not extend to C terminus YP_002233428.1 no significant database matches YP_002233437.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_002233446.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002233448.1 no significant database matches YP_002233449.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_002233458.1 no significant database matches YP_002233470.1 Similar to N terminus of Porphyromonas gingivalis (Bacteroides gingivalis) rbr rubrerythrin (rr). UniProt:Q9AGG3 (EMBL:AE017172) (200 aa) fasta scores: E()=3.4e-16, 46.099% id in 141 aa YP_002233490.1 Similar to Escherichia coli zrar transcriptional regulatory protein zrar. UniProt:P14375 (EMBL:ECHYDHGA) (441 aa) fasta scores: E()=7.8e-48, 40.618% id in 421 aa YP_002233506.1 Similar to Burkholderia pseudomallei (Pseudomonas pseudomallei) hypothetical protein. UniProt:Q63JC8 (EMBL:BX571966) (685 aa) fasta scores: E()=9e-80, 51.643% id in 639 aa; contains 45 amino acid N terminal truncation YP_002233517.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_002233519.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002233522.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_002233527.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002233529.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002233530.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_002233531.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_002233533.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002233535.1 synthesizes RNA primers at the replication forks YP_002233540.1 family S53 serine peptidase YP_002233557.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002233559.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002233568.1 acts as a molecular chaperone to fold and export lipase A YP_002233575.1 family S53 serine peptidase YP_002233579.1 catalyzes the conversion of citrate to isocitrate YP_002233580.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_002233583.1 catalyzes the oxidation of malate to oxaloacetate YP_002233587.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002233588.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002233590.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_002233601.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_002233603.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002233604.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002233605.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002233606.1 the hook connects flagellar basal body to the flagellar filament YP_002233608.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_002233609.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_002233610.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002233612.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002233613.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002233617.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002233618.1 catalyzes the conversion of O-succinylhomoserine into homocysteine YP_002233631.1 streptomycin 3'-adenyltransferase YP_002233635.1 This CDS contains an in-frame opal codon, UGA, at position 197. This opal codon encodes selenocysteine, which forms the active-site of the protein YP_002233638.1 possibly involved in the formation of formate dehydrogenase YP_002233639.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_002233730.1 catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system YP_002233732.1 Contains many Hep_Hag repeats and haemagglutinin motifs YP_002233739.1 Similar to Escherichia coli taud alpha-ketoglutarate-dependent taurine dioxygenase, (2- aminoethanesulfonate dioxygenase) (sulfate starvation-induced protein 3) (ssi3). UniProt:P37610 (EMBL:ECPS1) (282 aa) fasta scores: E()=2.6e-32, 37.319% id in 276 aa; contains extra 22 amino acids at N terminus YP_002233745.1 Similar to ) bacteriophage sfii (shigella flexneri bacteriophage ii). gtrb UniProt:P68668 (EMBL:AF021347 (309 aa) fasta scores: E()=8.8e-58, 54.072% id in 307 aa; contains additional C terminal 42 amino acids YP_002233771.1 Similar to Xanthobacter autotrophicus dhlb (s)-2-haloacid dehalogenase, (2-haloalkanoic acid dehalogenase) (l-2-haloacid dehalogenase) (halocarboxylic acid halidohydrolase). UniProt:Q60099 (EMBL:XADHLB) (253 aa) fasta scores: E()=1.5e-10, 33.495% id in 206 aa; contains C terminal truncation fo 24 amino acids YP_002233778.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002233788.1 Contains extra N-terminal 40 amino acids YP_002233798.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_002233802.1 Similar to BCAL0451, 96.488% identity (96.488% ungapped) in 484 aa overlap (1-484:1-484), and BCAM2493, 68.153% identity (68.153% ungapped) in 471 aa overlap (14-484:12-482) YP_002233806.1 catalyzes the formation of fumarate from aspartate YP_002233819.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002233820.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002233824.1 similar to periplasmic-binding component of ABC transporters YP_002233825.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002233826.1 similar to ATP-binding component of ABC transporters YP_002233827.1 family C45 cysteine peptidase YP_002233837.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002233840.1 family C44 cysteine peptidase YP_002233842.1 predicted polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_002233855.1 family S33 serine peptidase YP_002233861.1 Similar over its N-terminal half to phosphoenolpyruvate phosphomutase, and over the C-terminal half to sugar nucleotidyltransferase YP_002233876.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_002233889.1 catalyzes the formation of catechol from salicylate YP_002233901.1 secondary glycine betaine transporter betu YP_002233906.1 family T2 threonine peptidase YP_002233912.1 family M55 metallo peptidase YP_002233924.1 family T3 threonine peptidase YP_002233930.1 aliphatic amidase; catalyzes the hydrolysis of short-chain aliphatic amides to their organic acids and can also transfer the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates YP_002233934.1 family C39 cysteine peptidase YP_002233935.1 Similar to an internal region of the Bordetella pertussis dermonecrotic toxin Dnt YP_002233944.1 Weakly similar to the listed database matches. YP_002233962.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_002233970.1 Similar to the C-terminal part of escherichia coli RNA 2'-phosphotransferase KptA YP_002233981.1 Similar to the N-terminal half of Escherichia coli 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG YP_002233982.1 Similar to the C-terminal half of Escherichia coli 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase HpaG YP_002234038.1 activates fatty acids by binding to coenzyme A YP_002234056.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_002234067.1 Similar over its internal region to Burkholderia cepacia (Pseudomonas cepacia) fusaric acid resistance protein FusC. YP_002234091.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002234098.1 catalyzes the formation of L-proline from L-ornithine YP_002234117.1 putative transport protein YP_002234136.1 family S9 unassigned serine peptidase YP_002234155.1 Possible gene remnant. Similar to Rhizobium sp. (strain ngr234) probable conjugal transfer protein TraC UniProt:P55419 (EMBL:U00090 (102 aa) fasta scores: E()=7.3, 32.530% id in 83 aa, and to the N-terminal region of Burkholderia pseudomallei (strain 1710b) LigA UniProt:Q3JHX0 (EMBL:CP000125 (682 aa) fasta scores: E()=1.8, 29.688% id in 128 aa YP_002234170.1 Required for efficient pilin antigenic variation YP_002234179.1 family S33 serine peptidase YP_002234186.1 family M41 metallo peptidase YP_002234189.1 Doubtful CDS YP_002234193.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_002234200.1 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates YP_002234203.1 catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine YP_002234208.1 family S9 unassigned serine peptidase YP_002234221.1 family S33 serine peptidase YP_002234226.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_002234227.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_002234230.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_002234241.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_002234244.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002234246.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002234254.1 activates fatty acids by binding to coenzyme A YP_002234272.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_002234284.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002234294.1 This gene appears to be a fusion of two adjacent genes that are separated in the burkholderiae and several other organism. YP_002234324.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_002234341.1 subfamily M20D metallo peptidase YP_002234356.1 family S9 unassigned serine peptidase YP_002234360.1 family S11 serine peptidase YP_002234381.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_002234393.1 putative cell wall lysis peptidase YP_002234403.1 family S9 unassigned serine peptidase YP_002234424.1 catalyzes the formation of putrescine from agmatine YP_002234433.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_002234440.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_002234445.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002234456.1 catalyzes the formation of L-aspartate to iminoaspartate in NAD(+) biosynthesis YP_002234460.1 family S33 serine peptidase YP_002234462.1 member of a large family of NAD or NADP-dependent oxidoreductases; paralogs occur in many bacteria YP_002234470.1 No significant database matches. YP_002234475.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_002234479.1 Almost identical to Burkholderia cepacia transcriptional activator CepR SWALL:Q9ZIU0 (EMBL:AF019654) (239 aa) fasta scores: E(): 4e-99, 99.58% id in 239 aa, and Burkholderia vietnamiensis N-acyl homoserine lactone transcriptional regulator CepR SWALL:Q93PF4 (EMBL:AF333007) (239 aa) fasta scores: E(): 5.4e-99, 99.58% id in 239 aa YP_002234481.1 Previously sequenced as Burkholderia cepacia acyl homoserine lactone synthase CepI SWALL:Q9ZIU1 (EMBL:AF019654) (202 aa) fasta scores: E(): 7.4e-86, 100% id in 202 aa. Highly similar to Burkholderia vietnamiensis AHL synthase CepI SWALL:Q9AM53 (EMBL:AF330016) (202 aa) fasta scores: E(): 1.6e-77, 90.09% id in 202 aa. The CepI autoinducer synthase produces N-hexanoyl-acylhomoserine lactone (C6-HSL) and N-octanoyl-acylhomoserine lactone (C8-HSL) signaling molecules YP_002234483.1 No significant database matches. YP_002234485.1 No significant database matches. YP_002234486.1 No significant database matches. YP_002234487.1 No significant database matches. YP_002234489.1 No significant database matches. YP_002234492.1 No significant database matches. YP_002234498.1 No significant database matches. YP_002234499.1 No significant database matches. YP_002234502.1 No significant database matches. YP_002234503.1 No significant database matches. YP_002234504.1 No significant database matches. YP_002234505.1 No significant database matches. YP_002234506.1 No significant database matches. YP_002234507.1 No significant database matches. YP_002234508.1 No significant database matches. YP_002234509.1 No significant database matches. YP_002234510.1 No significant database matches. YP_002234511.1 No significant database matches. YP_002234513.1 No significant database matches. YP_002234514.1 No significant database matches. YP_002234515.1 No significant database matches. YP_002234516.1 No significant database matches. YP_002234517.1 No significant database matches. YP_002234519.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002234520.1 No significant database matches. YP_002234521.1 No significant database matches. YP_002234522.1 No significant database matches. YP_002234523.1 No significant database matches. YP_002234524.1 No significant database matches. YP_002234529.1 No significant database matches. YP_002234530.1 No significant database matches. YP_002234533.1 transposase proposed to express due to -1 translational frameshift at the sequence 5'-AAAAAC-3' YP_002234550.1 Similar to the C-terminal region of pyruvate dehydrogenase E1 component YP_002234552.1 paralogs to the E1 component of pyruvate dehydrogenase subunit E1 YP_002234562.1 family T3 threonine peptidase YP_002234566.1 No significant database matches. YP_002234595.1 No significant database matches. YP_002234601.1 No significant database matches. YP_002234604.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_002234605.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_002234608.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002234614.1 catalyzes the conversion of carbamoyl phosphate and aspartate to form N-carbamoyl aspartate YP_002234637.1 Similar to the C-terminal region of Homo sapiens (human) UDP-glucuronic acid decarboxylase 1 UXS1 UniProt:Q8NBZ7 (EMBL:AC018878 (420 aa) fasta scores: E()=6.7e-61, 53.548% id in 310 aa YP_002234646.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_002234648.1 family C44 cysteine peptidase YP_002234656.1 N-terminus is similar to an internal region of Homo sapiens (Human) apoptosis regulator BCL-2 UniProt:P10415 (239 aa) fasta scores: E()=0.64, 37.778% id in 90 aa YP_002234678.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002234679.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002234683.1 NadM-Nudix subfamily; involved in creation of nicotanimide adenine dinucleotide NAD from either biosynthetic or salvage pathways YP_002234689.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002234696.1 Similar to codons 85 to 450 of Lycopersicon esculentum (Tomato) zeaxanthin epoxidase, chloroplast precursor. UniProt:P93236 (EMBL:LEZEAXAN) (669 aa) fasta scores: E()=5.8e-16, 27.869% id in 366 aa, and to Burkholderia cenocepacia HI2424 flavoprotein monooxygenase precursor. UniProt:Q4LP64 (EMBL:AAHL01000034) (392 aa) fasta scores: E()=1.1e-142, 96.939% id in 392 aa YP_002234707.1 family S33 serine peptidase YP_002234708.1 Similar to BCAL3299, 76.119% identity (77.166% ungapped) in 737 aa overlap (1-736:1-728) YP_002234710.1 family S33 serine peptidase YP_002234721.1 catalyzes the formation of pyruvate and acetaldehyde from 4-hydroxy-2-ketovaleric acid; involved in the degradation of phenylpropionate YP_002234722.1 catalyzes the formation of acetyl-CoA from acetalaldehyde YP_002234727.1 N-terminal region is similar to Azospirillum brasilense putative carboxymethylenebutenolidase UniProt:Q43914 (EMBL:X67216 (231 aa) fasta scores: E()=2.4e-26, 40.435% id in 230 aa YP_002234730.1 catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde in the final enzymatic step of quinolinate biosynthesis YP_002234742.1 Similar, but extended at the N-terminus, to Ralstonia solanacearum (pseudomonas solanacearum) probable typeisecretion system outer membrane efflux transmembrane protein UniProt:Q8XQP1 (EMBL:AL646053 (483 aa) fasta scores: E()=2.3e-102, 68.107% id in 486 aa YP_002234743.1 Putative alternative start site at codon 37 YP_002234749.1 subfamily M20A metallo peptidase YP_002234750.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_002234764.1 Similar C-terminus of /NCIB 9086/R18194)) hypothetical protein. UniProt:Q399I4 (EMBL:CP000152) (140 aa) fasta scores: E()=6.1e-25, 89.394% id in 66 aa, and similar to Marinobacter aquaeolei VT8 hypothetical protein. UniProt:Q36P97 (EMBL:AALG01000013) (75 aa) fasta scores: E()=6e-06, 42.188% id in 64 aa YP_002234765.1 family S11 serine peptidase YP_002234769.1 Similar to C-terminus from codon 2485 of Burkholderia pseudomallei (Pseudomonas pseudomallei) BpaA. UniProt:Q6Y660 (EMBL:AY177757) (5431 aa) fasta scores: E()=2.3e-47, 26.575% id in 2555 aa, and similar to entire protein of Burkholderia ambifaria AMMD outer membrane autotransporter barrel precursor. UniProt:Q3F6T0 (EMBL:AAJL01000009) (2371 aa) fasta scores: E()=0, 85.799% id in 2366 aa YP_002234770.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia AU 1054 hypothetical protein precursor. UniProt:Q44UI6 (EMBL:AAHI01000054) (230 aa) fasta scores: E()=4.3e-80, 95.434% id in 219 aa YP_002234776.1 catalyzes the formation of glutamate from glutamine YP_002234781.1 Similar, but truncated 18 aa to Burkholderia cenocepacia AU 1054 hypothetical protein precursor. UniProt:Q44UH4 (EMBL:AAHI01000054) (208 aa) fasta scores: E()=1.4e-59, 88.021% id in 192 aa YP_002234790.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia HI2424 regulatory protein, lysr:lysr, substrate-binding. UniProt:Q4LHC0 (EMBL:AAHL01000108) (317 aa) fasta scores: E()=7.6e-115, 99.003% id in 301 aa, and simlar to entire protein of Burkholderia ambifaria AMMD regulatory protein, lysr:lysr, substrate-binding. UniProt:Q3F6U6 (EMBL:AAJL01000009) (301 aa) fasta scores: E()=1.2e-110, 95.017% id in 301 aa YP_002234792.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002234810.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia HI2424 hypothetical protein. UniProt:Q4LVF1 (EMBL:AAHL01000012) (153 aa) fasta scores: E()=7.1e-30, 98.864% id in 88 aa, and similar to entire protein of Burkholderia cenocepacia AU 1054 putative membrane protein precursor. UniProt:Q44VA8 (EMBL:AAHI01000046) (63 aa) fasta scores: E()=1.5e-18, 98.413% id in 63 aa, and smiilar, but extended at the N-terminus, to Burkholderia ambifaria AMMD hypothetical protein. UniProt:Q3F6W7 (EMBL:AAJL01000009) (91 aa) fasta scores: E()=4.9e-26, 90.805% id in 87 aa YP_002234816.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia HI2424 hypothetical protein. UniProt:Q4LVE5 (EMBL:AAHL01000012) (367 aa) fasta scores: E()=2.3e-52, 95.238% id in 147 aa, and similar to entire protein of )/ncib 9086/r18194)). hypothetical protein. UniProt:Q399Q4 (EMBL:AR559934 (148 aa) fasta scores: E()=1.7e-48, 86.486% id in 148 aa YP_002234820.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia AU 1054 general substrate transporter:major facilitator superfamily. UniProt:Q44V97 (EMBL:AAHI01000046) (441 aa) fasta scores: E()=3.4e-128, 98.063% id in 413 aa, and smiilar to entire protein of Burkholderia ambifaria AMMD general substrate transporter:major facilitator superfamily. UniProt:Q3FHP9 (EMBL:AAJL01000001) (417 aa) fasta scores: E()=1.1e-113, 86.441% id in 413 aa YP_002234829.1 Similar to Pseudomonas aeruginosa. PchR UniProt:P40883 (EMBL:AR403595 (296 aa) fasta scores: E()=4.6e-75, 68.571% id in 280 aa, and to Burkholderia cenocepacia HI2424 helix-turn-helix, AraC type. UniProt:Q4LVD0 (EMBL:AAHL01000012) (372 aa) fasta scores: E()=7.6e-146, 97.581% id in 372 aa. Possible alternative start site at codon 60. Burkholderia genome sequencing projects predict the longer CDS, whilst experimental evidence from Pseudomonas aeruginosa predicts the shorter form of the CDS YP_002234831.1 family S33 serine peptidase YP_002234832.1 catalyzes the second reaction in the pyochelin biosynthetic pathway, the conversion of isochorismate to salicylate and pyruvate. YP_002234833.1 involved in the conversion of chorismate to salicylate YP_002234846.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002234847.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_002234853.1 Similar to, but truncated at the N-terminus to ) salmonella enterica subsp. enterica serovar typhimurium. vrgs UniProt:Q93IR3 (EMBL:AJ320483 (729 aa) fasta scores: E()=9.6e-45, 29.595% id in 740 aa, and simlar to entire protein of ) burkholderia cenocepacia hi2424. rhs element vgr protein precursor. UniProt:Q4LVA4 (EMBL:AAHL01000012 (706 aa) fasta scores: E()=0, 98.017% id in 706 aa YP_002234890.1 family S9 unassigned serine peptidase YP_002234892.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_002234896.1 Similar, but truncated at the N-terminus, to Burkholderia cenocepacia AU 1054. hypothetical protein. UniProt:Q45D44 (EMBL:AAHI01000001 (190 aa) fasta scores: E()=2.6e-45, 97.959% id in 147 aa, and similar, but truncated at the N-terminus, to Burkholderia cenocepacia hi2424. hypothetical protein. UniProt:Q4LV74 (EMBL:AAHL01000012 (190 aa) fasta scores: E()=2.6e-45, 97.959% id in 147 aa, and similar to entire protein of to )/ncib 9086/r18194)). hypothetical protein. UniProt:Q399Y9 (EMBL:CP000152 (147 aa) fasta scores: E()=2e-44, 93.197% id in 147 aa YP_002234906.1 family M4 metallo peptidase YP_002234907.1 subfamily M24B metallo peptidase YP_002234914.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002234925.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_002234927.1 C-terminus is similar to Cellvibrio mixtus. CelC UniProt:Q336L6 (EMBL:AF003697 (1050 aa) fasta scores: E()=1.4e-11, 29.915% id in 234 aa, and to Burkholderia cenocepacia hi2424. coagulation factor 5/8 type, c-terminal:coagulation factor 5/8 type, c-terminal precursor. UniProt:Q4LV43 (EMBL:AAHL01000012 (487 aa) fasta scores: E()=8.5e-175, 96.802% id in 469 aa YP_002234939.1 family S33 serine peptidase YP_002234940.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_002234941.1 catalyzes the formation of betaine from betaine aldehyde YP_002234942.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_002234944.1 no significant database hits YP_002234957.1 family S9 unassigned serine peptidase YP_002234963.1 Required in the synthesis of PPQ, but its exact function is unknown YP_002234964.1 possibly involved in transport of pyrroloquinoline quinone transport YP_002234965.1 Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis; probably provides the glutamate and tyrosine residues that are cross-linked and modified to form the coenzyme YP_002234967.1 family S33 serine peptidase YP_002234970.1 Similar, but truncated at the N-terminus, to burkholderia cenocepacia au 1054. cytochrome c, class i. UniProt:Q45DB5 (EMBL:AAHI01000001 (470 aa) fasta scores: E()=1.1e-148, 97.236% id in 398 aa YP_002234971.1 Similar, but extended at the N-terminus, to Rhodoferax fermentans hip high-potential iron-sulfur protein (hipip). UniProt:P80882 (75 aa) fasta scores: E()=1.1e-11, 48.684% id in 76 aa, and similar to entire protein of burkholderia cenocepacia hi2424. high potential iron-sulfur protein precursor. UniProt:Q4LWY0 (EMBL:AAHL01000008 (104 aa) fasta scores: E()=2.1e-42, 98.077% id in 104 aa YP_002234973.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002234978.1 catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue YP_002235001.1 Similar, but truncated at the N-terminus, to burkholderia cenocepacia au 1054. hypothetical protein precursor. UniProt:Q45DF0 (EMBL:AAHI01000001 (130 aa) fasta scores: E()=7.1e-27, 90.217% id in 92 aa, and similar, but truncated at the N-terminus, to ) burkholderia cenocepacia hi2424. hypothetical protein precursor. UniProt:Q4LWU7 (EMBL:AAHL01000008 (130 aa) fasta scores: E()=7.1e-27, 90.217% id in 92 aa, and similar to the entire protein of /ncib 9086/r18194)). hypothetical protein. UniProt:Q39AC9 (EMBL:CP000152 (92 aa) fasta scores: E()=1.2e-24, 82.609% id in 92 aa YP_002235004.1 Possible alternative translational start sites YP_002235010.1 Similar, but truncated at the N-terminus, to burkholderia cenocepacia hi2424. helix-turn-helix, arac type:thij/pfpi. UniProt:Q4LWT8 (EMBL:AAHL01000008 (355 aa) fasta scores: E()=8.7e-125, 99.398% id in 332 aa, and similar to entire protein of burkholderia cenocepacia au 1054. helix-turn-helix, arac type:thij/pfpi precursor. UniProt:Q45DF9 (EMBL:AAHI01000001 (332 aa) fasta scores: E()=1.4e-124, 99.096% id in 332 aa YP_002235020.1 This CDS is highly repetitive and contains a C-terminal YadA domain, althought the hit is before the PFam gathering threshold. YP_002235034.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002235053.1 family S33 serine peptidase YP_002235066.1 Possible alternative translational start sites YP_002235079.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002235081.1 family S53 serine peptidase YP_002235087.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002235096.1 Similar to BCAM1186, 68.153% identity (68.153% ungapped) in 471 aa overlap (12-482:14-484), and BCAL0451, 68.153% identity (68.153% ungapped) in 471 aa overlap (12-482:14-484) YP_002235102.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002235104.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002235105.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_002235115.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_002235119.1 subfamily M50B metallo peptidase YP_002235124.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002235127.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_002235143.1 Similar to Burkholderia sp. nf100. fedb UniProt:Q25C65 (EMBL:AB235840 (501 aa) fasta scores: E()=1.6e-19, 36.743% id in 479 aa, and to )/ncib 9086/r18194)). hypothetical protein. UniProt:Q394I0 (EMBL:CP000152 (436 aa) fasta scores: E()=1.7e-106, 63.014% id in 438 aa YP_002235145.1 Fenitrothion is an organophosphorous pesticide YP_002235161.1 catalyzes the formation of selenophosphate from selenide and ATP YP_002235171.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_002235177.1 subfamily M20D metallo peptidase YP_002235199.1 family S12 serine peptidase YP_002235203.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_002235208.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_002235217.1 similar to the C-terminus of Q45CY5_9BURK and similar to entire protein of Q39B13_BURS3 YP_002235218.1 Similar, but truncated at the N-terminus, to ) burkholderia cenocepacia hi2424. hypothetical protein. UniProt:Q4LQD0 (EMBL:AAHL01000028 (121 aa) fasta scores: E()=1.4e-34, 96.078% id in 102 aa, and similar to entire protein of )/ncib 9086/r18194)). hypothetical protein. UniProt:Q39B14 (EMBL:CP000152 (102 aa) fasta scores: E()=3.9e-33, 91.176% id in 102 aa YP_002235231.1 with HmuTU is involved in the import of hemin YP_002235244.1 family S12 serine peptidase YP_002235251.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_002235270.1 specific inhibitor of chromosomal initiation of replication in vitro; inds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002235277.1 This CDS overlaps 29 nt at the N-terminus with the preceding CDS YP_002235294.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_002235300.1 family S9 unassigned serine peptidase YP_002235302.1 Catalyzes the conversion of citrate to isocitrate YP_002235303.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_002235304.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_002235334.1 catalyzes the hydrolysis of acylphosphate YP_002235338.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002235364.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_002235366.1 Possible gene remnant. Similar to the C-terminal region of Pseudomonas fluorescens hypothetical protein UniProt:Q4KEN9 (EMBL:CP000076 (219 aa) fasta scores: E()=2.2e-34, 53.631% id in 179 aa YP_002235379.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002235380.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002235382.1 Similar to ) burkholderia cenocepacia hi2424. gcn5-related n-acetyltransferase. UniProt:Q4LRL3 (EMBL:AAHL01000023 (192 aa) fasta scores: E()=2.5e-59, 92.308% id in 169 aa YP_002235385.1 subfamily M20D metallo peptidase YP_002235386.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_002235391.1 catalyzes the conversion of ferulic acid to feruloyl-CoA YP_002235393.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA YP_002235396.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002235397.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_002235401.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_002235413.1 Similar, but truncated at the N-terminus, to Burkholderia ambifaria AMMD hypothetical protein UniProt:Q3FCG1 (EMBL:AAJL01000004 (179 aa) fasta scores: E()=3.8e-44, 89.552% id in 134 aa, and similar, but extended at the N-terminus, to Burkholderia cenocepacia HI2424 hypothetical protein UniProt:Q4LRQ3 (EMBL:AAHL01000023 (127 aa) fasta scores: E()=6.7e-44, 94.488% id in 127 aa YP_002235421.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_002235435.1 family S33 serine peptidase YP_002153395.1 homology to YyaA doesn't extend to N and C termini YP_002153403.1 Similar to Escherichia coli prop effector proQ SWALL:PROQ_ECOLI (SWALL:P45577) (232 aa) fasta scores: E(): 0.015, 30.66% id in 150 aa; homology doesn't extend to N and C termini YP_002153406.1 Similar to Azotobacter vinelandii potential molybdenum-pterin-binding-protein ModG SWALL:Q44529 (EMBL:Z49882) (142 aa) fasta scores: E(): 3.6e-17, 48.57% id in 140 aa, and to the C-terminal region Azotobacter vinelandii molybdenum transport protein ModE modE SWALL:MODE_AZOVI (SWALL:P37733) (270 aa) fasta scores: E(): 5.8e-15, 47.14% id in 140 aa YP_002153418.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_002153419.1 putative cyclodeaminase YP_002153420.1 C-terminal region is similar to the C-terminus of Pyrococcus furiosus Xaa-Pro dipeptidase PepQ SWALL:PEPQ_PYRFU (SWALL:P81535) (348 aa) fasta scores: E(): 1.6e-09, 24.47% id in 237 aa. Full length CDS is similar to Agrobacterium tumefaciens Xaa-Pro dipeptidase pepQ SWALL:Q8U6Q0 (EMBL:AE009404) (392 aa) fasta scores: E(): 4e-120, 74.22% id in 388 aa YP_002153436.1 potentially involved in iron uptake pathway YP_002153437.1 Potentially involved in purine nucleotide biosynthesis YP_002153438.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002153444.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_002153446.1 Similar to Pseudomonas aeruginosa fmn reductase msuE SWALL:MSUE_PSEAE (SWALL:O31038) (186 aa) fasta scores: E(): 8.7e-38, 63.21% id in 174 aa; possibly involved in sulphur utilisation YP_002153449.1 Similar to Burkholderia cepacia hth-type transcriptional regulator DgdR dgdR SWALL:DGDR_BURCE (SWALL:P16931) (294 aa) fasta scores: E(): 2.1e-22, 32.55% id in 258 aa; homology doesn't extend to C terminus YP_002153455.1 homology doesn't extend to C terminus YP_002153463.1 Possible gene remnant. Similar to the C-terminal region of Burkholderia vietnamiensis G4 ATPase-like protein UniProt:Q4BRL4 (EMBL:AAEH02000004 (704 aa) fasta scores: E()=1.4e-119, 76.850% id in 419 aa, and to the full length Burkholderia ambifaria mc40-6 histidine kinase UniProt:A0T569 (EMBL:AAUZ01000001 (472 aa) fasta scores: E()=1.4e-70, 47.511% id in 442 aa YP_002153465.1 Similar to N terminus of Pseudomonas sp. VLB120 transcriptional activator stdR SWALL:O50213 (EMBL:AF031161) (207 aa) fasta scores: E(): 5.5e-11, 37.39% id in 115 aa YP_002153466.1 Similar to Sulfolobus acidocaldarius lipolytic enzyme saL SWALL:O73957 (EMBL:AF071233) (314 aa) fasta scores: E(): 4.2e-11, 25.18% id in 278 aa; homology doesn't extend to N terminus; family S33 serine peptidase YP_002153470.1 Similar to Sulfolobus acidocaldarius lipolytic enzyme saL SWALL:O73957 (EMBL:AF071233) (314 aa) fasta scores: E(): 1.4e-17, 29.16% id in 288 aa; homology doesn't extend to N terminus; family S33 serine peptidase YP_002153472.1 family S33 serine peptidase YP_002153474.1 possibly involved in drug efflux YP_002153475.1 family S33 serine peptidase YP_002153479.1 family S9 unassigned serine peptidase YP_002153482.1 Similar to central section of Azotobacter vinelandii dihydrolipoyllysine-residue succinyltransferase component of 2- oxoglutarate dehydrogenase complex sucB SWALL:ODO2_AZOVI (SWALL:P20708) (398 aa) fasta scores: E(): 0.69, 35.36% id in 82 aa YP_002153483.1 stationary phase protein that binds TrpR repressor YP_002153494.1 Similar to Ralstonia solanacearum ExuT exuT SWALL:Q93AS8 (EMBL:AF417111) (439 aa) fasta scores: E(): 1.7e-30, 30.78% id in 445 aa; has N terminal extension YP_002153495.1 Similar to Agrobacterium tumefaciens dihydrodipicolinate synthase DapA SWALL:Q8UJS7 (EMBL:AE008961) (309 aa) fasta scores: E(): 4.7e-72, 62.91% id in 302 aa. Weakly similar to Bacillus subtilis dihydrodipicolinate synthase DapA SWALL:DAPA_BACSU (SWALL:Q04796) (290 aa) fasta scores: E(): 4.5e-11, 26.66% id in 285 aa YP_002153497.1 Similar to BCAL0113, 69.136% identity (70.000% ungapped) in 486 aa overlap (1-486:19-498) YP_002153498.1 Similar to Porphyromonas gingivalis dtdp-4-dehydrorhamnose reductase rfbD SWALL:Q7MUG2 (EMBL:AE017177) (285 aa) fasta scores: E(): 6.3e-12, 34.09% id in 264 aa; homology doesn't extend to N terminus; putative signal sequence at N terminus YP_002153501.1 Similar to Klebsiella pneumoniae citrate-proton symporter citH SWALL:CIT1_KLEPN (SWALL:P16482) (444 aa) fasta scores: E(): 1.8e-48, 36.36% id in 407 aa; homology doesn't extend to N terminus YP_002153503.1 Similar to Escherichia coli arginine-binding periplasmic protein 2 precursor artJ SWALL:ARTJ_ECOLI (SWALL:P30860) (243 aa) fasta scores: E(): 2.1e-08, 28.09% id in 267 aa; contains additional 24 amino acids in central portion of predicted protein YP_002153505.1 has 18 amino acid C terminal extension YP_002153508.1 possible histidine utilization repressor YP_002153509.1 Osa protein from pSa of Shigella is involved in suppression of oncogenic activity of Agrobacterium tumefaciens YP_002153510.1 Similar to C terminus of Myxococcus xanthus RNA-directed DNA polymerase from retron mx65 SWALL:RT65_MYXXA (SWALL:P23071) (427 aa) fasta scores: E(): 4e-22, 42.73% id in 337 aa YP_002153516.1 Similar to Pseudomonas putida pca regulon regulatory protein pcaR SWALL:PCAR_PSEPU (SWALL:Q52154) (291 aa) fasta scores: E(): 1.8e-15, 28.06% id in 253 aa; N terminus is slightly truncated YP_002153518.1 Contains 3 pentapeptide repeat units YP_002153520.1 contains predicted signal peptide YP_002153521.1 also contains 2 CBS domains YP_002153524.1 Similar to Bacillus subtilis choline transport system permease protein OpubB opubB SWALL:OPBB_BACSU (SWALL:Q45461) (217 aa) fasta scores: E(): 2e-20, 40.62% id in 192 aa; has N terminal extension of 25 amino acids YP_002153532.1 Similar to Escherichia coli, and Shigella flexneri transcriptional regulator NanR nanR SWALL:NANR_ECOLI (SWALL:P45427) (263 aa) fasta scores: E(): 1.3e-05, 24.37% id in 238 aa; slight N terminal truncation YP_002153535.1 Similar to Pseudomonas putida branched-chain amino acid ABC transporter, permease protein SWALL:Q88Q78 (EMBL:AE016776) (339 aa) fasta scores: E(): 3.3e-64, 58.8% id in 318 aa; has N terminal extension YP_002153538.1 Similar to Bacillus stearothermophilus N-carbamoyl-L-amino acid hydrolase amaB SWALL:AMB2_BACST (SWALL:Q53389) (409 aa) fasta scores: E(): 2.9e-42, 37.12% id in 404 aa; has 15 amino acid N terminal extension; family M20 unassigned metallo peptidase YP_002153543.1 no significant database hits YP_002153544.1 family S33 serine peptidase YP_002153546.1 Similar to Salmonella typhi hypothetical protein sty2347 SWALL:Q8Z5F0 (EMBL:AL627273) (235 aa) fasta scores: E(): 4.6e-36, 53.36% id in 193 aa; homology doesn't extend to N terminus YP_002153548.1 family S12 serine peptidase YP_002153567.1 family S33 serine peptidase YP_002153572.1 Similar to Escherichia coli methyl-accepting chemotaxis protein i tsR SWALL:MCP1_ECOLI (SWALL:P02942) (551 aa) fasta scores: E(): 2.6e-52, 44.72% id in 474 aa; homology doesn't extend to N terminus YP_002153587.1 Similar to Comamonas testosteroni TeiR teiR SWALL:Q6URL0 (EMBL:AY363220) (391 aa) fasta scores: E(): 3.5e-06, 26.16% id in 386 aa; slight truncation at N terminus YP_002153588.1 Similar to Agrobacterium vitis endo-polygalacturonase precursor pehA SWALL:P77818 (EMBL:U73161) (549 aa) fasta scores: E(): 1.3e-09, 31.85% id in 700 aa YP_002153590.1 has homology to DctQ component of Tripartite ATP-independent periplasmic (TRAP) transporters YP_002153609.1 no significant database hits YP_002153612.1 Probably involved in production of an antifungal agent YP_002153613.1 Probably involved in production of an antifungal agent YP_002153614.1 Possibly involved in production of an antifungal agent YP_002153616.1 family S33 serine peptidase YP_002153621.1 Similar to Escherichia coli, Escherichia coli O6, and Escherichia coli O157:H7 ribose transport system permease protein RbsC rbsC SWALL:RBSC_ECOLI (SWALL:P04984) (321 aa) fasta scores: E(): 1.8e-23, 37.45% id in 307 aa; has C terminal extension YP_002153622.1 membrane component of a putative sugar ABC transporter system YP_002153623.1 no significant database hits YP_002153624.1 Central portion similar to central portion of Escherichia coli, and Shigella flexneri aerobic respiration control sensor protein ArcB arcB SWALL:ARCB_ECOLI (SWALL:P22763) (778 aa) fasta scores: E(): 1.2e-18, 34.48% id in 261 aa YP_002153625.1 Similar to C terminus of Bacteroides thetaiotaomicron two-component system sensor histidine kinase/response regulator, hybrid SWALL:Q8AB44 (EMBL:AE016926) (1370 aa) fasta scores: E(): 2.6e-17, 32.66% id in 251 aa YP_002153626.1 Contains many weak matches to Hep_Hag repeat of bacterial haemagglutinins. Possible pseudogene. CDS lacks predicted N-terminal signal sequence, therefore it is known if this protein will be correctly processed YP_002153627.1 C terminus similar to C terminus of Bordetella avium outer membrane protein a precursor ompA SWALL:OMPA_BORAV (SWALL:Q05146) (194 aa) fasta scores: E(): 8.8e-10, 36.11% id in 144 aa YP_002153630.1 C terminus similar (with gaps) to Thermus thermophilus UvrAbc system protein a uvrA SWALL:UVRA_THETH (SWALL:Q56242) (952 aa) fasta scores: E(): 5.4e-32, 43.78% id in 1014 aa YP_002153635.1 no significant database hits YP_002153636.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002153637.1 no significant database hits YP_002153639.1 no significant database hits YP_002153646.1 Similar to Bradyrhizobium japonicum blr0485 protein SWALL:Q89X37 (EMBL:BA000040) (407 aa) fasta scores: E(): 1.3e-78, 63.46% id in 364 aa; possible 44 amino acid truncation of N terminus YP_002153652.1 no significant database hits YP_002153654.1 N terminus similar to N terminus of Rhodobacter capsulatus hydrogenase transcriptional regulatory protein Hupr1 hupr1 SWALL:HUPR_RHOCA (SWALL:P26408) (492 aa) fasta scores: E(): 9.9e-15, 32.11% id in 246 aa; contains response regulator domain and HD domain YP_002153655.1 C terminus similar to C terminus of Rhodobacter sphaeroides hydrogen uptake histidine-kinase hupT SWALL:Q53162 (EMBL:L37195) (443 aa) fasta scores: E(): 1.6e-22, 33.98% id in 356 aa YP_002153658.1 Similar to Escherichia coli, and Escherichia coli O157:H7 IcC protein icC SWALL:ICC_ECOLI (SWALL:P36650) (275 aa) fasta scores: E(): 1.6e-16, 31.33% id in 217 aa; homology does not extend to C terminus YP_002153662.1 Similar to the C-terminal region of Saccharomyces cerevisiae (baker's yeast) Urea amidolyase Dur1,2 UniProt:P32528 (EMBL:M64926 (1835 aa) fasta scores: E()=2.4e-147, 44.399% id in 1214 aa YP_002153663.1 Similar to the N-terminal region of Saccharomyces cerevisiae (baker's yeast) urea amidolyase DUR1,2 UniProt:P32528 (EMBL:M64926 (1835 aa) fasta scores: E()=1.8e-57, 41.426% id in 589 aa YP_002153664.1 C terminus is similar to C terminus of Escherichia coli taurine transport system permease protein TauC tauC SWALL:TAUC_ECOLI (SWALL:Q47539) (275 aa) fasta scores: E(): 9.4e-17, 30.83% id in 227 aa YP_002153665.1 Similar to Synechococcus sp. nitrate transport ATP-binding protein NrtD SWALL:NRTD_SYNP7 (SWALL:P38046) (274 aa) fasta scores: E(): 3.8e-38, 45.88% id in 255 aa; homology does not extend to N terminus YP_002153666.1 Similar to Bordetella bronchiseptica putative extracellular solute-binding protein SWALL:Q7WKE7 (EMBL:BX640443) (306 aa) fasta scores: E(): 5e-23, 33.61% id in 241 aa; N terminus truncated by approx 50 amino acids YP_002153672.1 no significant database hits YP_002153680.1 Similar to Photorhabdus luminescens similar to putative oxygenase SWALL:Q7N0S8 (EMBL:BX571871) (334 aa) fasta scores: E(): 5.6e-44, 39.26% id in 326 aa; has C terminal extension YP_002153683.1 Expression of aidA is regulated by the cep quorum sensing system. AidA is involved in killing of C. elegans YP_002153686.1 Similar to Chlorobium tepidum hypothetical protein ct0439 SWALL:Q8KF89 (EMBL:AE012821) (454 aa) fasta scores: E(): 2.6e-43, 36.5% id in 400 aa; homology does not extend to N terminus YP_002153691.1 subfamily A24A aspartic peptidase YP_002153694.1 Contains domain involved in protein export YP_002153701.1 contains type II secretion system protein F domain YP_002153703.1 Similar to C terminus of Pseudomonas resinovorans hypothetical protein Orf9 orf9 SWALL:Q8GI20 (EMBL:AB088420) (567 aa) fasta scores: E(): 4.4e-74, 58.03% id in 305 aa YP_002153704.1 Similar to N terminus of Acinetobacter baumannii p-hydroxyphenylacetate hydroxylase c1:reductase component c1-hpaH SWALL:Q6Q271 (EMBL:AY566613) (315 aa) fasta scores: E(): 1.4e-25, 43.86% id in 171 aa YP_002153707.1 N terminus is similar to Pseudomonas putida, and Pseudomonas sp. carboxymethylenebutenolidase clcD SWALL:CLCD_PSEPU (SWALL:P11453) (236 aa) fasta scores: E(): 1.8e-22, 36.53% id in 219 aa YP_002153709.1 may form heterodimer with product of BCAS0320 YP_002153711.1 Similar to central portion of Bombyx mori fibroin heavy chain precursor fibH SWALL:FBOH_BOMMO (SWALL:P05790) (5263 aa) fasta scores: E(): 1e-152, 31.7% id in 3908 aa YP_002153715.1 Similar to uncultured bacterium 582 ABC transporter, substrate-binding protein SWALL:Q6SF77 (EMBL:AY458649) (437 aa) fasta scores: E(): 9.3e-47, 34.39% id in 407 aa; N terminus shorter by 23 amino acids YP_002153720.1 Homology does not extend to N terminal signal peptide YP_002153725.1 Contains many weak matches to haemagglutinin and Hep_Hag repeats YP_002153728.1 Similar to N terminus of Bradyrhizobium sp. nodulation protein NolA nolA SWALL:NOLA_BRASN (SWALL:P50330) (237 aa) fasta scores: E(): 1.2e-07, 37.09% id in 124 aa YP_002153729.1 family S33 serine peptidase YP_002153731.1 C terminus similar to C terminus of Escherichia coli taurine transport system permease protein TauC tauC SWALL:TAUC_ECOLI (SWALL:Q47539) (275 aa) fasta scores: E(): 6.4e-21, 35.13% id in 222 aa YP_002153737.1 Similar to Escherichia coli taurine transport system permease protein TauC tauC SWALL:TAUC_ECOLI (SWALL:Q47539) (275 aa) fasta scores: E(): 7.3e-20, 33.46% id in 245 aa; homology does not extend to N termini YP_002153745.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002153747.1 with XylFH is part of the high affinity xylose ABC transporter YP_002153748.1 Similar to Escherichia coli, Escherichia coli O6, Escherichia coli O157:H7, and Shigella flexneri xylose transport system permease protein XylH xylH SWALL:XYLH_ECOLI (SWALL:P37389) (393 aa) fasta scores: E(): 2.7e-70, 54.98% id in 371 aa; homology does not extend to far N-terminus YP_002153749.1 no significant database hits YP_002153759.1 catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica YP_002153762.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_002153780.1 Similar to C terminus of Pseudomonas syringae peptide ABC transporter, ATP-binding protein SWALL:Q88AY1 (EMBL:AE016856) (613 aa) fasta scores: E(): 2.6e-65, 53.23% id in 387 aa YP_002153792.1 no significant database hits YP_002153794.1 Similar to C terminus of Alicyclobacillus sendaiensis kumamolisin-as scpA SWALL:Q8GB88 (EMBL:AB085855) (553 aa) fasta scores: E(): 3.2e-10, 33.01% id in 415 aa; family S53 serine peptidase YP_002153796.1 no significant database hits YP_002153797.1 family M4 metallo peptidase YP_002153799.1 no significant database hits YP_002153812.1 Similar to Xanthomonas campestris oxidoreductase SWALL:Q8PBP0 (EMBL:AE012205) (300 aa) fasta scores: E(): 1.7e-57, 59.37% id in 288 aa; contains 4 amino acid N terminal extension YP_002153813.1 no significant database hits YP_002153814.1 no significant database hits YP_002153817.1 Similar to Enterococcus faecalis sapb protein, putative SWALL:Q837S2 (EMBL:AE016949) (239 aa) fasta scores: E(): 4.8e-14, 37.22% id in 180 aa; homology does not extend to C terminus YP_002153830.1 Similar to Chelatobacter heintzii nitrilotriacetate monooxygenase component a ntaA SWALL:NTAA_CHEHE (SWALL:P54989) (453 aa) fasta scores: E(): 2.6e-34, 35.3% id in 422 aa; homology doesn't extend to N terminus YP_002153834.1 Similar to Escherichia coli nickel transport system permease protein NikB nikB SWALL:NIKB_ECOLI (SWALL:P33591) (314 aa) fasta scores: E(): 1.1e-26, 33.44% id in 299 aa; contains 30 amino acid N terminal extension; contains putative N terminal signal sequence YP_002153846.1 contains TM1410 hypothetical-related domain YP_002153852.1 Similar to Escherichia coli glucitol operon repressor srlR SWALL:SRLR_ECOLI (SWALL:P15082) (257 aa) fasta scores: E(): 4.9e-21, 35.74% id in 249 aa; contains 20 amino acid N terminal extension YP_002153854.1 no significant database hits YP_002153859.1 Similar to Ralstonia solanacearum probable multidrug resistance transport transmembrane protein rs00128 SWALL:Q8XVV1 (EMBL:AL646071) (388 aa) fasta scores: E(): 1.1e-30, 40.69% id in 376 aa; homology does not extend to N terminus; contains 60 amino acid N terminal extension YP_002153860.1 Similar to Pseudomonas putida mutt/nudix family protein SWALL:Q88HT5 (EMBL:AE016786) (132 aa) fasta scores: E(): 4.7e-08, 41.12% id in 107 aa; homology does not extend to C terminus; contains 30 amino acid N terminal extension; hydrolyses nucleoside diphosphate derivatives YP_002153863.1 Similar to Bordetella parapertussis putative membrane protein SWALL:Q7WAW6 (EMBL:BX640426) (202 aa) fasta scores: E(): 2.2e-20, 45.23% id in 168 aa; contains 20 amino acid C terminal truncation YP_002153867.1 Similar to Burkholderia pseudomallei hypothetical protein SWALL:Q63X13 (EMBL:BX571965) (278 aa) fasta scores: E(): 6.2e-32, 56.03% id in 257 aa; contains 20 amino acid C terminal truncation; contains 35 amino acid gap after codon 73 YP_002153873.1 Similar to Bacillus pseudofirmus cytochrome c oxidase polypeptide ii precursor ctaC SWALL:COX2_BACPF (SWALL:Q04441) (342 aa) fasta scores: E(): 6.6e-27, 34.39% id in 314 aa; homology does not extend to N terminus YP_002153874.1 Similar to Bacillus PS3 cytochrome c oxidase polypeptide i ctaD SWALL:COX1_BACP3 (SWALL:P16262) (615 aa) fasta scores: E(): 2.1e-89, 44.69% id in 575 aa; homology does not extend to N and C termini YP_002153876.1 Similar to Acetobacter polyoxogenes, and Acetobacter europaeus alcohol dehydrogenase cytochrome c subunit precursor adhB SWALL:CYCA_ACEPO (SWALL:Q03318) (468 aa) fasta scores: E(): 5e-57, 46.3% id in 406 aa; homology does not extend to N and C termini YP_002153888.1 possible virulence factor YP_002153889.1 Similar to Salmonella typhi bacteriophage tail fiber protein SWALL:Q8Z6S9 (EMBL:AL627270) (341 aa) fasta scores: E(): 1.1e-10, 42.6% id in 230 aa; homology does not extend to C terminus YP_002153891.1 Similar to Bacteriophage P2 baseplate assembly protein j J SWALL:VPJ_BPP2 (SWALL:P51767) (302 aa) fasta scores: E(): 2.7e-06, 33.5% id in 197 aa; homology doesn't extend to N terminus YP_002153894.1 Similar to Bacteriophage P2 gene d protein D SWALL:VPD_BPP2 (SWALL:P10312) (387 aa) fasta scores: E(): 5e-12, 28.69% id in 237 aa; homology does not extend to C terminus YP_002153898.1 alternative BcepMu42 C-termninus produced by ribosomal slippage. CDS lacks translational start YP_002153900.1 CDS is extended at the C-terminus in comparison to similar proteins, possible frameshift extends the CDS. Similar to Chromobacterium violaceum hypothetical protein UniProt:Q7NY03 (EMBL:AE016825 (88 aa) fasta scores: E()=5.5e-10, 51.899% id in 79 aa YP_002153902.1 Similar to Bacteriophage P2 major tail sheath protein fI SWALL:VPF1_BPP2 (SWALL:P22501) (395 aa) fasta scores: E(): 1.5e-17, 33.11% id in 302 aa; homology doesn't extend to N terminus YP_002153908.1 Possible alternative translational start site after codon 220 YP_002153910.1 Similar to N terminus of Bacteriophage Mu protein F SWALL:VPF_BPMU (SWALL:Q01259) (439 aa) fasta scores: E(): 6.3e-52, 50.56% id in 265 aa. possible minor head protein YP_002153911.1 Similar to Bacteriophage Mu protein gp29 29 SWALL:VG29_BPMU (SWALL:Q9T1W5) (512 aa) fasta scores: E(): 5.9e-23, 27.77% id in 450 aa; homology does not extend to N terminus YP_002153916.1 Similar to Erwinia carotovora hypothetical protein SWALL:Q6D3G6 (EMBL:BX950851) (224 aa) fasta scores: E(): 1.4e-05, 33.51% id in 182 aa. Putative lytic function YP_002153917.1 Rz1, out of frame, embedded proline-rich protein. Putative lytic function YP_002153922.1 no significant database hits YP_002153928.1 no significant database hits YP_002153931.1 no significant database hits YP_002153936.1 Similar to Clostridium acetobutylicum uncharacterized protein, mazg family SWALL:Q97HS8 (EMBL:AE007699) (123 aa) fasta scores: E(): 0.0095, 39.72% id in 73 aa; homology does not extend to N terminus YP_002153947.1 Similar to N terminus of Rhodopseudomonas palustris hypothetical protein SWALL:Q6N802 (EMBL:BX572599) (141 aa) fasta scores: E(): 1.9e-11, 62.5% id in 72 aa YP_002153949.1 Similar to N terminus of Xanthomonas campestris hypothetical protein xcc2052 SWALL:Q8P914 (EMBL:AE012311) (102 aa) fasta scores: E(): 9.2e-11, 71.69% id in 53 aa YP_002153965.1 contains putative SpoVT/AbrB-like domain - transcriptional regulator YP_002153967.1 Similar to Rhodopseudomonas palustris possible cation/heavy metal efflux pump, hlyd family secretion protein precursor ragD SWALL:Q6N8Z6 (EMBL:BX572598) (400 aa) fasta scores: E(): 5.5e-45, 44.72% id in 398 aa; contains 30 amino acid N and C terminal extensions YP_002153980.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002153982.1 no significant database hits YP_002153990.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_002153993.1 contains DNA binding motifs YP_002154006.1 no significant database hits YP_002154014.1 Similar to Anabaena sp. two-component hybrid sensor and regulator SWALL:Q8YW99 (EMBL:BA000019) (1333 aa) fasta scores: E(): 2.4e-108, 35.34% id in 1341 aa; contains 70 amino acid N terminal extension YP_002154015.1 no significant database hits YP_002154017.1 Similar to Lactobacillus plantarum manganese catalase SWALL:MCAT_LACPL (SWALL:P60355) (266 aa) fasta scores: E(): 8.8e-16, 30.99% id in 271 aa; contans 50 amino acid C terminal extension YP_002154019.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_002154021.1 no significant database hits YP_002154022.1 Similar to Alcaligenes eutrophus hypothetical protein SWALL:Q7WXF5 (EMBL:AY305378) (65 aa) fasta scores: E(): 1e-05, 49.18% id in 61 aa; contains 25 amino acid N terminal extension YP_002154025.1 no significant database hits YP_002154026.1 no significant database hits YP_002154031.1 Similar to Escherichia coli transposase insd for insertion element is2a/d/f/h/i/k SWALL:INSD_ECOLI (SWALL:P19777) (301 aa) fasta scores: E(): 1.2e-65, 60.37% id in 265 aa, and to C-terminus from codon 132 of Pseudomonas glumae transposase SWALL:O50654 (EMBL:AB011023) (401 aa) fasta scores: E(): 2.1e-98, 87.45% id in 271 aa YP_002154035.1 no significant database hits YP_002154037.1 Possible alternative translational start sites YP_002154038.1 C-terminus is similar to the C-terminus of Helicobacter hepaticus hypothetical protein hh1587 SWALL:Q7VFT8 (EMBL:AE017148) (181 aa) fasta scores: E(): 7e-05, 32.54% id in 126 aa YP_002154039.1 no significant database hits YP_002154041.1 Similar to Escherichia coli RhsB protein precursor rhsB SWALL:RHSB_ECOLI (SWALL:P16917) (1411 aa) fasta scores: E(): 1.7e-36, 28.13% id in 1276 aa; homology does not extend to the C terminus; Similar to Pseudomonas putida rhs-related protein SWALL:Q88I91 (EMBL:AE016785) (1385 aa) fasta scores: E(): 2e-149, 43.97% id in 1312 aa; homology does not extend to the C terminus YP_002154047.1 no significant database hits YP_002154048.1 no significant database hits YP_002154050.1 no significant database hits YP_002154054.1 no significant database hits YP_002154056.1 no significant database hits YP_002154057.1 no significant database hits YP_002154058.1 contains low-scoring match to TniQ domain YP_002154063.1 Similar to Rhizobium loti probable transcriptional regulator SWALL:Q98ML2 (EMBL:BA000012) (204 aa) fasta scores: E(): 2.5e-07, 30.53% id in 167 aa; homology does not extend to C terminus; N-terminus is similar to the N-terminus of Rhodopseudomonas palustris probable transcriptional regulator TetR family rpa3021 SWALL:CAE28462 (EMBL:BX572602) (195 aa) fasta scores: E(): 5.9e-08, 35.92% id in 103 aa YP_002154074.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_002154080.1 Possible alternative upstream translational start site YP_002154082.1 Similar to C-terminus of Bradyrhizobium japonicum nodulation protein v NodV or bll1715 SWALL:NODV_BRAJA (SWALL:P15939) (889 aa) fasta scores: E(): 2e-42, 35.11% id in 524 aa YP_002154085.1 paralogs to the E1 component of pyruvate dehydrogenase subunit E1 YP_002154089.1 Codons 38 to 215 are similar to codon 623 to the C-terminus of Vibrio parahaemolyticus putative transmembrane protein vp0400 SWALL:Q87SM2 (EMBL:AP005074) (271 aa) fasta scores: E(): 6.8e-07, 28.72% id in 188 aa YP_002154090.1 C-terminal region is similar to Photobacterium profundum hypothetical protein. UniProt:Q6LHQ1 (EMBL:CR378679 (715 aa) fasta scores: E()=6.7e-54, 30.143% id in 700 aa YP_002154095.1 C-terminal region is similar to Bradyrhizobium japonicum methionine sulfoxide reductase MsrB UniProt:Q89EM9 (EMBL:BA000040 (139 aa) fasta scores: E()=6.6e-26, 51.095% id in 137 aa YP_002154096.1 Similar to Rhizobium meliloti hypothetical protein smb20213 SWALL:Q92WX1 (EMBL:AL591985) (627 aa) fasta scores: E(): 7.6e-70, 61.55% id in 619 aa; N terminal 45 amino acids truncated YP_002154097.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002154098.1 contains Rieske [2Fe-2S] domain YP_002154100.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_002154102.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_002154104.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_002154105.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_002154106.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_002154108.1 contains thiolase domains YP_002154111.1 Similar to Pseudomonas aeruginosa ornithine utilization regulator oruR SWALL:ORUR_PSEAE (SWALL:P72171) (339 aa) fasta scores: E(): 4.1e-20, 35.17% id in 253 aa; homology doesn't extend to N terminus YP_002154115.1 Possible alternative translational start site after codon 12 YP_002154122.1 family T3 threonine peptidase YP_002154130.1 Similar to Burkholderia cenocepacia hypothetical protein SWALL:Q8VP11 (EMBL:AY028431) (4424 aa) fasta scores: E(): 7.1e-106, 31.65% id in 4657 aa; contains extra 550 amino acids in central section of protein YP_002154132.1 contains TonB-dependent receptor protein signature 1 YP_002154133.1 Similar to Bordetella bronchiseptica hypothetical protein SWALL:Q7WR58 (EMBL:BX640437) (128 aa) fasta scores: E(): 2.7, 40.47% id in 84 aa YP_002154138.1 Similar to Burkholderia mallei transcriptional regulator, lysr family SWALL:Q62MT9 (EMBL:CP000010) (351 aa) fasta scores: E(): 8.1e-25, 37.84% id in 288 aa; C terminal 50 amino acids truncated YP_002154145.1 no significant database hits YP_001989038.1 Similar to Pseudomonas syringae pv. maculicola putative partition protein ParA SWALL:Q93TE7 (EMBL:AF359557) (216 aa) fasta scores: E(): 1.7e-10, 28.44% id in 218 aa, and to Xanthomonas axonopodis partition protein A ParA SWALL:Q8NKZ8 (EMBL:AE008924) (208 aa) fasta scores: E(): 1.6e-11, 31.96% id in 219 aa YP_002235439.1 Weakly similar to Bacillus subtilis stage 0 sporulation protein J Spo0J SWALL:SP0J_BACSU (SWALL:P26497) (282 aa) fasta scores: E(): 1.1e-07, 29.71% id in 249 aa, and to the C-terminal region of Ralstonia solanacearum putative partitioning protein ParB or rsp0004 or rs01976 SWALL:Q8XTV0 (EMBL:AL646076) (334 aa) fasta scores: E(): 2.1e-13, 28.12% id in 256 aa YP_002235440.1 Similar to Escherichia coli p285 protein TrfA SWALL:Q52323 (EMBL:X00713) (285 aa) fasta scores: E(): 5.7e-19, 29.68% id in 283 aa, and to the C-terminal region of Escherichia coli TrfA transcriptional repressor protein SWALL:TRFA_ECOLI (SWALL:P07676) (382 aa) fasta scores: E(): 7.3e-19, 29.68% id in 283 aa YP_002235441.1 Similar to the C-terminal region of Staphylococcus aureus DNA polymerase III alpha subunit DnaE SWALL:DP3A_STAAU (SWALL:Q9F1K0) (1065 aa) fasta scores: E(): 6.9e-61, 25.64% id in 1045 aa, and to the full length Pseudomonas aeruginosa probable DNA polymerase alpha chain pa0669 SWALL:Q9I5Q2 (EMBL:AE004502) (1031 aa) fasta scores: E(): 3.6e-188, 52.96% id in 1044 aa YP_002235442.1 Similar to Ralstonia solanacearum hypothetical protein rsp0799 or rs01908 SWALL:Q8XRN2 (EMBL:AL646080) (523 aa) fasta scores: E(): 5.1e-31, 45.61% id in 524 aa, and to Xanthomonas axonopodis hypothetical protein xac1198 SWALL:Q8PN75 (EMBL:AE011749) (472 aa) fasta scores: E(): 1.8e-28, 34% id in 497 aa YP_002235443.1 Similar to N-terminal region of Ralstonia solanacearum hypothetical protein rsp0798 or rs01909 SWALL:Q8XRN3 (EMBL:AL646080) (272 aa) fasta scores: E(): 5.2e-32, 49.36% id in 235 aa. N-terminal region is similar to many proteins including: Pseudomonas putida putative cell division inhibitor SulA, pp3117 SWALL:AAN68725 (EMBL:AE016785) (206 aa) fasta scores: E(): 1.6e-20, 46.5% id in 200 aa. C-terminal region of the CDS overlaps the down stream CDS YP_002235444.1 Similar to Serratia marcescens reverse transcriptase RetA SWALL:O52209 (EMBL:AF027768) (495 aa) fasta scores: E(): 2.4e-151, 71.63% id in 497 aa, and to Bradyrhizobium japonicum Blr1915 protein blr1915 SWALL:BAC47180 (EMBL:AP005941) (491 aa) fasta scores: E(): 8.1e-128, 63.24% id in 487 aa YP_002235445.1 Poor database matches. Internal region is weakly similar to the N-terminal region of Bradyrhizobium japonicum Blr2564 protein SWALL:BAC47829 (EMBL:AP005944) (254 aa) fasta scores: E(): 0.0048, 26.25% id in 179 aa YP_002235446.1 Poor database matches. C-terminus is similar to the C-terminal region of Pseudomonas alcaligenes RepA SWALL:O30879 (EMBL:U88088) (276 aa) fasta scores: E(): 8.8e-21, 40.33% id in 238 aa YP_002235447.1 Weakly similar to Rhizobium meliloti hypothetical protein SWALL:Q91UR0 (EMBL:AJ304453) (239 aa) fasta scores: E(): 0.01, 24.28% id in 243 aa YP_002235449.1 Similar to Bradyrhizobium japonicum Blr6028 protein SWALL:Q89HG3 (EMBL:AP005957) (100 aa) fasta scores: E(): 2.5, 35.52% id in 76 aa, and to the N-terminal region of Shewanella oneidensis HlyD family secretion protein so3483 SWALL:Q8EBM7 (EMBL:AE015784) (369 aa) fasta scores: E(): 4.4, 38.02% id in 71 aa YP_002235450.1 Weakly similar to Proteus vulgaris conserved hypothetical protein Orf137 SWALL:Q8L2A0 (EMBL:AP004237) (151 aa) fasta scores: E(): 0.013, 22.51% id in 151 aa, and to Coxiella burnetii hypothetical protein cbu1865 SWALL:Q83AL8 (EMBL:AE016965) (175 aa) fasta scores: E(): 4.3, 26.75% id in 157 aa YP_002235451.1 Poor database matches. Weakly similar to the C-terminal region of Streptomyces griseoflavus hypothetical protein GilN SWALL:AAP69592 (EMBL:AY233211) (297 aa) fasta scores: E(): 6.4, 39.21% id in 51 aa YP_002235452.1 Similar to Rhizobium etli hypothetical protein yp034 SWALL:Q8KL58 (EMBL:U80928) (404 aa) fasta scores: E(): 2.7e-62, 43.21% id in 398 aa, and to Rhizobium loti hypothetical protein mlr9246 SWALL:Q981T1 (EMBL:AP003015) (412 aa) fasta scores: E(): 7.4e-54, 40% id in 395 aa. CDS is extended at the C-terminus in comparison to orthologues; none YP_002235453.1 N-terminus is similar to the N-terminal regions of Xanthomonas axonopodis hypothetical protein xacb0057 SWALL:Q8PRH5 (EMBL:AE008925) (395 aa) fasta scores: E(): 4.9e-25, 37.7% id in 313 aa, and Pseudomonas alcaligenes hypothetical protein SWALL:Q9XAX4 (EMBL:U88088) (522 aa) fasta scores: E(): 7.5e-23, 30.19% id in 414 aa YP_002235456.1 Similar to Escherichia coli TraG protein SWALL:TRG1_ECOLI (SWALL:P33790) (938 aa) fasta scores: E(): 4.6e-18, 24.34% id in 916 aa YP_002235457.1 Similar to Escherichia coli TraH protein precursor SWALL:TRH1_ECOLI (SWALL:P15069) (458 aa) fasta scores: E(): 7.9e-24, 28.44% id in 450 aa YP_002235458.1 Similar to Bacteriophage phiE125 conserved hypothetical protein Gp37 SWALL:Q8W6R4 (EMBL:AF447491) (330 aa) fasta scores: E(): 3.2e-52, 58.03% id in 336 aa, and to Sinorhizobium meliloti phage PBC5 hypothetical protein Orf76 SWALL:Q8W6F1 (EMBL:AF448724) (337 aa) fasta scores: E(): 3.9e-11, 34.67% id in 349 aa. CDS is extended at the C-terminus in comparison to orthologues YP_002235459.1 Similar to Shigella flexneri conserved hypothetical protein sf1348 SWALL:AAN42952 (EMBL:AE015160) (121 aa) fasta scores: E(): 4e-06, 39.7% id in 136 aa, and to the C-teminal region of Salmonella typhi hypothetical protein HCM1.27c SWALL:Q935R5 (EMBL:AL513383) (174 aa) fasta scores: E(): 7.3e-21, 47.36% id in 133 aa YP_002235460.1 Poor database matches. Weakly similar to an internal region of Escherichia coli DNA primase TraC SWALL:TRC4_ECOLI (SWALL:P27189) (1061 aa) fasta scores: E(): 6.9, 25.8% id in 155 aa; none YP_002235461.1 Similar to Escherichia coli TraF protein precursor SWALL:TRAF_ECOLI (SWALL:P14497) (247 aa) fasta scores: E(): 1.4e-08, 25.83% id in 240 aa, and to Sphingomonas aromaticivorans pilus assembly and synthesis protein precursor TraF SWALL:O85933 (EMBL:AF079317) (270 aa) fasta scores: E(): 3.6e-16, 31.07% id in 280 aa YP_002235464.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_002235465.1 Weakly similar to the N-terminal region of Escherichia coli TraN protein precursor SWALL:TRAN_ECOLI (SWALL:P24082) (602 aa) fasta scores: E(): 7.4, 22.18% id in 275 aa YP_002235466.1 Similar to Listeria monocytogenes hypothetical protein lmo2255 SWALL:Q8Y522 (EMBL:AL591982) (88 aa) fasta scores: E(): 0.53, 32.14% id in 84 aa, and to N-terminal region of Klebsiella pneumoniae probable cps biosynthesis glycosyltransferase SWALL:YC14_KLEPN (SWALL:Q48460) (465 aa) fasta scores: E(): 1.5, 30.69% id in 101 aa. Possible alternative translational start site YP_002235467.1 Similar to Sphingomonas aromaticivorans sex pilus assembly and mating pair formation protein precursor TrbC SWALL:O85936 (EMBL:AF079317) (254 aa) fasta scores: E(): 8.5e-08, 28.5% id in 214 aa. C-terminus is similar to the C-terminal region of Escherichia coli periplasmic protein TrbC precursor trbC SWALL:TRBC_ECOLI (SWALL:P18473) (212 aa) fasta scores: E(): 0.0006, 30.51% id in 154 aa YP_002235468.1 Similar to Escherichia coli TraU protein precursor SWALL:TRAU_ECOLI (SWALL:P18471) (330 aa) fasta scores: E(): 1.8e-56, 42.13% id in 337 aa YP_002235469.1 Similar to Escherichia coli TraW protein precursor SWALL:TRAW_ECOLI (SWALL:P18472) (210 aa) fasta scores: E(): 2.8e-17, 35.46% id in 203 aa YP_002235470.1 Similar to Rhizobium loti plasmid transfer protein, TraF mlr6188 SWALL:Q98A24 (EMBL:AP003008) (182 aa) fasta scores: E(): 0.00011, 30% id in 170 aa. C-terminus is similar to C-terminal region Bacillus subtilis signal peptidase I t sipt or bsu14410 SWALL:LEPT_BACSU (SWALL:P71013) (193 aa) fasta scores: E(): 0.0029, 32.52% id in 123 aa YP_002235471.1 Similar to Ralstonia solanacearum putative transmembrane protein rsc1615 or rs03978 SWALL:Q8XYZ1 (EMBL:AL646065) (55 aa) fasta scores: E(): 1.4, 30% id in 50 aa YP_002235472.1 Similar to Agrobacterium tumefaciens transcriptional regulator, GntR family atu3226 or agr_l_3177 SWALL:Q8UAZ1 (EMBL:AE009252) (244 aa) fasta scores: E(): 3.6e-11, 32.73% id in 223 aa, and to Rhizobium meliloti putative transcriptional regulator, GntR family protein rb1031 or smb21591 SWALL:Q92UR2 (EMBL:AL603645) (244 aa) fasta scores: E(): 7.3e-12, 33.5% id in 194 aa YP_002235473.1 Similar to Citrobacter freundii Nuc protein SWALL:Q8GFV6 (EMBL:AF550415) (183 aa) fasta scores: E(): 1.9e-18, 41.8% id in 177 aa, and to Pseudomonas putida putative nuclease SWALL:Q847E6 (EMBL:AF491307) (201 aa) fasta scores: E(): 3.4e-32, 56.42% id in 179 aa YP_002235474.1 Poor database matches. Weakly similar to an internal region of Podospora anserina NADH-ubiquinone oxidoreductase chain 2 ND2 SWALL:NU2M_PODAN (SWALL:P15578) (556 aa) fasta scores: E(): 4.9, 24.32% id in 111 aa YP_002235476.1 Weakly siimilar to Brucella suis transcriptional regulator, Ros/MucR family br0569 SWALL:Q8G1Y2 (EMBL:AE014365) (142 aa) fasta scores: E(): 1.9, 26.01% id in 123 aa, and to Brucella melitensis transcriptional regulatory protein bmei1364 SWALL:Q8YFZ8 (EMBL:AE009574) (161 aa) fasta scores: E(): 2.5, 26.01% id in 123 aa YP_002235478.1 No significant database matches. N-terminus overlaps the C-terminal region of pBS039 YP_002235479.1 Similar to Escherichia coli TraC protein SWALL:TRAC_ECOLI (SWALL:P18004) (875 aa) fasta scores: E(): 3.3e-45, 25.08% id in 849 aa, and to Sphingomonas aromaticivorans sex pilus assembly and synthesis protein TraC SWALL:O85942 (EMBL:AF079317) (856 aa) fasta scores: E(): 1.1e-66, 29% id in 855 aa YP_002235481.1 Similar to Escherichia coli, and Escherichia coli O157:H7 thiol:disulfide interchange protein dsbc precursor DsbC or XprA or b2893 or z4231 or ecs3765 SWALL:DSBC_ECOLI (SWALL:P21892) (236 aa) fasta scores: E(): 1.1e-14, 29.13% id in 230 aa; none YP_002235482.1 Similar to Escherichia coli TraB protein SWALL:TRB1_ECOLI (SWALL:P41067) (475 aa) fasta scores: E(): 9.2e-13, 26.57% id in 444 aa YP_002235483.1 Similar to Salmonella typhi TraK protein SWALL:Q8KNL8 (EMBL:AF411480) (246 aa) fasta scores: E(): 0.29, 21.9% id in 242 aa. N-terminus is similar to an internal region of Escherichia coli hypothetical protein YafA or b0239 SWALL:YAFA_ECOLI (SWALL:P04335) (414 aa) fasta scores: E(): 1.8, 30.53% id in 131 aa N-terminus overlaps the C-terminal region of pBS044 YP_002235484.1 Similar to Escherichia coli TraE protein SWALL:TRE1_ECOLI (SWALL:P08322) (188 aa) fasta scores: E(): 7e-05, 25% id in 136 aa YP_002235485.1 Weakly similar to Pseudomonas resinovorans putative pillus assembly protein TrhL SWALL:BAC41647 (EMBL:AB088420) (95 aa) fasta scores: E(): 0.017, 29.21% id in 89 aa, and to Vibrio cholerae sex pilus assembly protein TraL SWALL:Q8KQX8 (EMBL:AY055428) (95 aa) fasta scores: E(): 0.0094, 26.43% id in 87 aa YP_002235486.1 Poor database matches. Internal region is similar to the N-terminus of Pseudomonas aeruginosa hypothetical protein PA2110 SWALL:Q9I205 (EMBL:AE004638) (313 aa) fasta scores: E(): 0.8, 36.2% id in 58 aa; none YP_002235488.1 Similar to Shigella flexneri ipgF protein precursor IpgF or cp0135 SWALL:IPGF_SHIFL (SWALL:Q07568) (152 aa) fasta scores: E(): 2e-11, 35.33% id in 133 aa, and to Escherichia coli hypothetical protein SWALL:Q9AJ25 (EMBL:AF200363) (152 aa) fasta scores: E(): 6.6e-17, 40.39% id in 151 aa YP_002235489.1 Poor database matches. Similar to the C-terminal region of Xanthomonas axonopodis hypothetical protein XACB0048 SWALL:Q8PRI4 (EMBL:AE008925) (118 aa) fasta scores: E(): 0.35, 32.25% id in 62 aa YP_002235490.1 Similar to Ralstonia solanacearum hypothetical protein rsc2169 or rs01430 SWALL:Q8XXE5 (EMBL:AL646068) (247 aa) fasta scores: E(): 3.7e-41, 50% id in 244 aa, and to Yersinia pestis hypothetical protein ypo2700 or y1276 SWALL:Q8ZD89 (EMBL:AJ414153) (245 aa) fasta scores: E(): 3.6e-37, 48.01% id in 227 aa YP_002235491.1 Weakly similar to the N-terminal region of Candidatus Tremblaya princeps hypothetical protein SWALL:Q8KTR1 (EMBL:AF481102) (230 aa) fasta scores: E(): 4.3, 29.76% id in 84 aa YP_002235492.1 Similar to Bradyrhizobium japonicum Blr5140 protein SWALL:BAC50405 (EMBL:AP005953) (365 aa) fasta scores: E(): 2.2e-29, 37.1% id in 318 aa, and to Ralstonia solanacearum putative signal peptide protein rsc2510 or rs01072 SWALL:Q8XWG4 (EMBL:AL646070) (338 aa) fasta scores: E(): 1e-28, 34.53% id in 304 aa YP_002235493.1 No significant database matches to the full length CDS. C-terminal region is similar to Ralstonia solanacearum transcriptional activator protein SolR SWALL:SLR2_RALSO (SWALL:O30919) (236 aa) fasta scores: E(): 0.3, 24.35% id in 234 aa, and to Agrobacterium tumefaciens LuxR family transcriptional regulator atu2727 or agr_c_4942 SWALL:Q8UBX2 (EMBL:AE009219) (267 aa) fasta scores: E(): 0.29, 27.43% id in 277 aa. Possible alternative translational start site. YP_002235494.1 C-terminal region is weakly similar to an internal region of Bradyrhizobium japonicum Bll8156 protein SWALL:BAC53421 (EMBL:AP005964) (828 aa) fasta scores: E(): 2e-16, 24.27% id in 725 aa. Internal region is weakly similar to Ralstonia solanacearum probable transmembrane protein rsp1524 or rs04801 SWALL:Q8XPW2 (EMBL:AL646085) (505 aa) fasta scores: E(): 9e-23, 27.37% id in 453 aa YP_002235496.1 N-terminal region is similar to the N-terminal regions of Escherichia coli TraI protein SWALL:TRI2_ECOLI (SWALL:P22706) (1756 aa) fasta scores: E(): 2.4e-29, 27.03% id in 899 aa, and Escherichia coli TrwC protein SWALL:Q47673 (EMBL:X63150) (966 aa) fasta scores: E(): 1.6e-37, 33.5% id in 967 aa YP_002235497.1 Similar to N-terminal regions of Escherichia coli TraD protein SWALL:TRD2_ECOLI (SWALL:P22708) (738 aa) fasta scores: E(): 3.9e-43, 27.33% id in 633 aa, and to plasmid R100 TraD protein SWALL:BAA78884 (EMBL:AP000342) (738 aa) fasta scores: E(): 3.9e-43, 27.33% id in 633 aa YP_002235499.1 Doubtful CDS. No significant database matches YP_002235501.1 Similar to Salmonella typhi hypothetical protein r0155 SWALL:Q9L5I7 (EMBL:AF250878) (55 aa) fasta scores: E(): 0.00019, 42.59% id in 54 aa YP_002235502.1 Doubtful CDS. No significant database matches YP_002235503.1 Similar to Ralstonia solanacearum hypothetical protein rsc3357 or rs02632 SWALL:Q8XU37 (EMBL:AL646074) (75 aa) fasta scores: E(): 2.7e-08, 53.73% id in 67 aa YP_002235504.1 Poor database matches. Weakly similar to Homo sapiens prepro-alpha-1 collagen precursor COL1A1 SWALL:Q15201 (EMBL:X00820) (181 aa) fasta scores: E(): 4.4, 26.37% id in 91 aa YP_002235506.1 Similar to Ralstonia oxalatica hypothetical protein SWALL:CAD61121 (EMBL:AJ536756) (690 aa) fasta scores: E(): 4.1e-69, 39.31% id in 725 aa, and to Bradyrhizobium japonicum Bll0065 protein SWALL:BAC45330 (EMBL:AP005935) (712 aa) fasta scores: E(): 2.7e-43, 34.91% id in 676 aa YP_002235509.1 none; No significant database matches YP_002235510.1 Similar to Escherichia coli putative methyltransferase YfeA SWALL:Q9S4X2 (EMBL:AF106329) (227 aa) fasta scores: E(): 4.1e-48, 61.35% id in 207 aa, and to Yersinia pestis putative DNA methylase YPMT1.64c or y5181 or y1085 SWALL:Q9R3Z4 (EMBL:AL117211) (225 aa) fasta scores: E(): 9.7e-48, 60.87% id in 207 aa YP_002235511.1 Poor database matches. Weakly similar to the N-terminal region of Streptomyces coelicolor puative turgor pressure regulator KdpE or sco5872 or sc2e9.13 SWALL:O54138 (EMBL:AL939125) (227 aa) fasta scores: E(): 7.6, 26.11% id in 157 aa YP_002235513.1 Poor database matches. C-terminal region is weakly similar to Xylella fastidiosa hypothetical protein xf2086 SWALL:Q9PBQ4 (EMBL:AE004024) (197 aa) fasta scores: E(): 0.00084, 26.77% id in 183 aa. Possible alternative translational start site YP_002235514.1 Similar to Ralstonia oxalatica hypothetical protein SWALL:CAD61120 (EMBL:AJ536756) (275 aa) fasta scores: E(): 3.4e-72, 63.86% id in 274 aa, and to Pseudomonas aeruginosa conserved hypothetical protein SWALL:AAN62307 (EMBL:AF440524) (275 aa) fasta scores: E(): 1.9e-70, 63.86% id in 274 aa YP_002235515.1 Similar to Ralstonia solanacearum hypothetical protein rsp0728 or rs01700 SWALL:Q8XRV3 (EMBL:AL646080) (39 aa) fasta scores: E(): 5e-08, 65.71% id in 35 aa YP_002235516.1 Poor database matches. Weakly similar to the N-terminal region of Rhizobium meliloti hypothetical protein SWALL:Q9AGT8 (EMBL:AF327371) (197 aa) fasta scores: E(): 0.02, 28.83% id in 163 aa YP_002235519.1 Highly similar to Burkholderia cepacia insertion element IS407 hypothetical 10.0 kDa protein SWALL:YI74_BURCE (SWALL:P24580) (87 aa) fasta scores: E(): 7e-32, 98.85% id in 87 aa, and Ralstonia solanacearum ISRso14-transposase OrfA protein SWALL:Q8XGL4 (EMBL:AL646083) (87 aa) fasta scores: E(): 2.2e-29, 93.1% id in 87 aa YP_002235520.1 submitted as non partial; Similar to Xanthomonas campestris IS1477 transposase xcc1455 SWALL:Q8PAM6 (EMBL:AE012246) (337 aa) fasta scores: E(): 1.1e-67, 56.7% id in 328 aa. C-terminal region is similar to Ralstonia solanacearum ISRso14-transposase OrfB protein SWALL:Q8XF72 (EMBL:AL646083) (275 aa) fasta scores: E(): 3.4e-91, 87.17% id in 273 aa YP_002235521.1 Similar to Bacillus subtilis UDP-N-acetylenolpyruvoylglucosamine reductase MurB or bsu15230 SWALL:MURB_BACSU (SWALL:P18579) (303 aa) fasta scores: E(): 1.7e-17, 28.88% id in 277 aa, and to Thermoanaerobacter tengcongensis UDP-N-acetylenolpyruvoylglucosamine reductase murb or tte1836 SWALL:Q8R8Z6 (EMBL:AE013135) (302 aa) fasta scores: E(): 3.7e-22, 32.02% id in 281 aa. CDS is truncated at the N-terminus in comparison to orthologues YP_002235522.1 Similar to Bradyrhizobium japonicum Bll6480 protein SWALL:BAC51745 (EMBL:AP005958) (234 aa) fasta scores: E(): 3e-21, 33.62% id in 232 aa, and to Brucella melitensis hypothetical protein bmei0629 SWALL:Q8YI16 (EMBL:AE009505) (228 aa) fasta scores: E(): 1.1e-12, 28.89% id in 218 aa YP_002235523.1 Poor database matches. Weakly similar to the N-terminal region of Bacillus subtilis adenine deaminase AdeC or Ade or bsu14520 SWALL:ADEC_BACSU (SWALL:P39761) (577 aa) fasta scores: E(): 4.9, 22.25% id in 355 aa YP_002235524.1 Similar to Xanthomonas axonopodis hypothetical protein xaca0025 SWALL:Q8PRN3 (EMBL:AE008924) (183 aa) fasta scores: E(): 1.2e-23, 39.77% id in 176 aa, and to Pseudomonas resinovorans hypothetical protein SWALL:Q8G8R1 (EMBL:AB088420) (197 aa) fasta scores: E(): 1.3e-19, 36.95% id in 184 aa YP_002235525.1 submitted as non partial; C-terminal region is similar to Escherichia coli, and Escherichia coli O6 integrase/recombinase XerD or XprB or b2894 or c3474 SWALL:XERD_ECOLI (SWALL:P21891) (298 aa) fasta scores: E(): 0.41, 25% id in 368 aa. Full length CDS is similar to Ralstonia solanacearum putative integrase/recombinase protein rsp0902 or rs01673 SWALL:Q8XRF2 (EMBL:AL646081) (566 aa) fasta scores: E(): 4.5e-22, 31.33% id in 600 aa. Possible alternative translational start site YP_002235527.1 Poor database matches. Similar to the C-terminal region of Streptococcus pneumoniae IS630-SPN1, transposase sp2014 and sp0016 SWALL:Q97CV1 (EMBL:AE007490) (112 aa) fasta scores: E(): 6.2, 26.41% id in 106 aa YP_002235528.1 Similar to Rhizobium loti nitrogen regulatory protein NtrR mll1670 SWALL:Q98K22 (EMBL:AP002998) (132 aa) fasta scores: E(): 1.5e-21, 53.48% id in 129 aa, and to Pseudomonas syringae plasmid stability protein StbB or psptob0018 SWALL:STBB_PSESM (SWALL:Q52562) (139 aa) fasta scores: E(): 0.047, 32.37% id in 139 aa YP_002235529.1 Similar to Salmonella dublin virulence-associated protein VagC SWALL:VAGC_SALDU (SWALL:Q05459) (76 aa) fasta scores: E(): 0.0099, 39.34% id in 61 aa, and to Rhizobium meliloti NtrP protein r02417 or smc03949 SWALL:Q9L381 (EMBL:AJ277847) (90 aa) fasta scores: E(): 5e-13, 54.11% id in 85 aa YP_002235530.1 Similar to Pseudomonas putida putative ligase SWALL:Q8VMP4 (EMBL:AJ344068) (316 aa) fasta scores: E(): 3.6e-52, 45.62% id in 320 aa, and to an internal region Pseudomonas aeruginosa probable ATP-dependent DNA ligase pa2138 SWALL:Q9I1X7 (EMBL:AE004641) (840 aa) fasta scores: E(): 1.3e-53, 45.69% id in 337 aa