-- dump date 20140619_014119 -- class Genbank::CDS -- table cds_note -- id note YP_001941190.1 COG0412: Dienelactone hydrolase and related enzymes, Ralstonia solanacearum; KEGG, K01061 YP_001941191.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001941192.1 COG0104: Adenylosuccinate synthase, Caulobacter vibrioides; KEGG, K01939 YP_001941193.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001941195.1 RepA4 protein YP_001941196.1 COG1475: Predicted transcriptional regulators, Ralstonia solanacearum; ParB4 protein YP_001941197.1 COG1192: ATPases involved in chromosome partitioning, Ralstonia solanacearum; ParA4 protein YP_001941198.1 COG2220: Predicted Zn-dependent hydrolases of the beta-lactamase fold, Ralstonia solanacearum YP_001941199.1 COG1309: Transcriptional regulator, Vibrio cholerae YP_001941200.1 COG0655: Multimeric flavodoxin WrbA, Mycobacterium leprae YP_001941202.1 COG3109: Activator of osmoprotectant transporter ProP, Pseudomonas aeruginosa; KEGG, K03607 YP_001941203.1 COG0346: Lactoylglutathione lyase and related lyases, Caulobacter vibrioides YP_001941206.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001941207.1 COG1566: Multidrug resistance efflux pump, Brucella melitensis YP_001941209.1 COG1289: Predicted membrane protein, Brucella melitensis YP_001941210.1 COG1846: Transcriptional regulators, Brucella melitensis; KEGG, K06075 YP_001941211.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Agrobacterium tumefaciens strain C58 YP_001941212.1 catalyzes the formation of 2-oxobutanoate from L-threonine; involved in ectoine utilization YP_001941213.1 putative cyclodeaminase YP_001941214.1 COG0006: Xaa-Pro aminopeptidase, Agrobacterium tumefaciens strain C58; KEGG, K01271 YP_001941215.1 COG3608: Predicted deacylase, Mesorhizobium loti; KEGG, K06987 YP_001941216.1 COG1522: Transcriptional regulators, Mesorhizobium loti YP_001941217.1 COG1012: NAD-dependent aldehyde dehydrogenases, Sinorhizobium meliloti; KEGG, K00135 YP_001941218.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Sinorhizobium meliloti YP_001941219.1 in some organisms the DhaK and DhaL subunits are encoded by separate genes; in others they are fused; functions along with DhaM to phosphorylate dihydroxyacetone YP_001941220.1 COG1221: Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain, Pseudomonas aeruginosa YP_001941221.1 COG0583: Transcriptional regulator, Salmonella typhimurium LT2 YP_001941222.1 catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica YP_001941224.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2 YP_001941225.1 COG1893: Ketopantoate reductase, Pyrococcus horikoshii; KEGG, K00077 YP_001941227.1 contains MaoC domain YP_001941228.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Pseudomonas aeruginosa; KEGG, K07749 YP_001941229.1 COG0169: Shikimate 5-dehydrogenase, Pseudomonas aeruginosa; KEGG, K00014 YP_001941230.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001941231.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit, Agrobacterium tumefaciens strain C58; KEGG, K01607 YP_001941232.1 COG1457: Purine-cytosine permease and related proteins, Bacillus subtilis; KEGG, K03457 YP_001941233.1 COG1012: NAD-dependent aldehyde dehydrogenases, Sinorhizobium meliloti; KEGG, K00128 YP_001941234.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Sinorhizobium meliloti YP_001941235.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Sinorhizobium meliloti YP_001941236.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Agrobacterium tumefaciens strain C58 YP_001941239.1 COG1802: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001941240.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Agrobacterium tumefaciens strain C58; KEGG, K00492 YP_001941241.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Agrobacterium tumefaciens strain C58; KEGG, K02055 YP_001941242.1 COG1176: ABC-type spermidine/putrescine transport system, permease component I, Sinorhizobium meliloti; KEGG, K02054 YP_001941243.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Sinorhizobium meliloti; KEGG, K02053 YP_001941244.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Sinorhizobium meliloti; KEGG, K02052 YP_001941245.1 COG1802: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001941247.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Agrobacterium tumefaciens strain C58 YP_001941248.1 COG1349: Transcriptional regulators of sugar metabolism, Bacillus subtilis; KEGG, K03436 YP_001941249.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001941250.1 COG3395: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti YP_001941251.1 transports degraded pectin products into the bacterial cell YP_001941252.1 COG0431: Predicted flavoprotein, Pseudomonas aeruginosa; KEGG, K00299 YP_001941253.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Pseudomonas aeruginosa; KEGG, K04091 YP_001941254.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001941255.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti; KEGG, K07124 YP_001941256.1 COG0346: Lactoylglutathione lyase and related lyases, Mesorhizobium loti; KEGG, K07032 YP_001941258.1 COG2128: Uncharacterized conserved protein, Sinorhizobium meliloti YP_001941259.1 COG2814: Arabinose efflux permease, Mesorhizobium loti YP_001941260.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Sinorhizobium meliloti YP_001941261.1 COG3511: Phospholipase C, Mycobacterium tuberculosis CDC1551 YP_001941262.1 COG2771: DNA-binding HTH domain-containing proteins, Mesorhizobium loti YP_001941263.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum YP_001941264.1 contains ankyrin repeats YP_001941266.1 COG5435: Uncharacterized conserved protein, Salmonella typhimurium LT2 YP_001941267.1 COG3209: Rhs family protein, Salmonella typhimurium LT2 YP_001941268.1 COG1893: Ketopantoate reductase, Mycobacterium tuberculosis CDC1551; KEGG, K00077 YP_001941269.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001941270.1 COG0277: FAD/FMN-containing dehydrogenases, Salmonella typhimurium LT2; KEGG, K06911 YP_001941272.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001941273.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941274.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001941275.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001941278.1 COG1012: NAD-dependent aldehyde dehydrogenases, Bacillus halodurans; KEGG, K00128 YP_001941279.1 COG1454: Alcohol dehydrogenase, class IV, Agrobacterium tumefaciens strain C58; KEGG, K00217 YP_001941280.1 COG3485: Protocatechuate 3,4-dioxygenase beta subunit, Agrobacterium tumefaciens strain C58; KEGG, K04098 YP_001941283.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941284.1 COG1132: ABC-type multidrug transport system, ATPase and permease components, Pasteurella multocida; KEGG, K06147 YP_001941285.1 COG1309: Transcriptional regulator, Mesorhizobium loti YP_001941286.1 COG1764: Predicted redox protein, regulator of disulfide bond formation, Ralstonia solanacearum YP_001941287.1 COG0657: Esterase/lipase, Ralstonia solanacearum; KEGG, K01066 YP_001941288.1 COG1454: Alcohol dehydrogenase, class IV, Agrobacterium tumefaciens strain C58; KEGG, K00217 YP_001941289.1 COG1380: Putative effector of murein hydrolase LrgA, Ralstonia solanacearum; KEGG, K05338; LrgA protein YP_001941290.1 COG1346: Putative effector of murein hydrolase, Ralstonia solanacearum; KEGG, K05339; LrgB protein YP_001941292.1 stationary phase protein that binds TrpR repressor YP_001941293.1 COG1741: Pirin-related protein, Ralstonia solanacearum; KEGG, K06911 YP_001941294.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001941296.1 COG0591: Na+/proline symporter, Thermoplasma volcanium YP_001941297.1 COG1574: Predicted metal-dependent hydrolase with the TIM-barrel fold, Mycobacterium tuberculosis CDC1551; KEGG, K07047 YP_001941298.1 COG0523: Putative GTPases (G3E family), Sinorhizobium meliloti YP_001941299.1 COG2175: Probable taurine catabolism dioxygenase, Pseudomonas aeruginosa; KEGG, K03119 YP_001941300.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001941301.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Pseudomonas aeruginosa; KEGG, K02049 YP_001941302.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component, Pseudomonas aeruginosa; KEGG, K02050 YP_001941303.1 COG2259: Predicted membrane protein, Escherichia coli O157:H7 YP_001941304.1 COG1091: dTDP-4-dehydrorhamnose reductase, Aeropyrum pernix; KEGG, K00067 YP_001941306.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001941307.1 COG0583: Transcriptional regulator, Yersinia pestis YP_001941308.1 extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols; part of the bacterial aromatic compound degradation pathway YP_001941309.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001941310.1 KEGG, K07045 YP_001941311.1 COG0684: Demethylmenaquinone methyltransferase, Sinorhizobium meliloti YP_001941312.1 COG0725: ABC-type molybdate transport system, periplasmic component, Yersinia pestis; KEGG, K02020 YP_001941314.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941315.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941316.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli K12 YP_001941317.1 COG1414: Transcriptional regulator, Pseudomonas aeruginosa YP_001941318.1 COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Caulobacter vibrioides YP_001941319.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001941320.1 COG3653: N-acyl-D-aspartate/D-glutamate deacylase, Ralstonia solanacearum; KEGG, K06015 YP_001941321.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001941322.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941323.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Agrobacterium tumefaciens strain C58 YP_001941325.1 COG0473: Isocitrate/isopropylmalate dehydrogenase, Escherichia coli O157:H7; KEGG, K00056 YP_001941327.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Escherichia coli K12; KEGG, K00540 YP_001941328.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00135 YP_001941329.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Escherichia coli O157:H7; KEGG, K00470 YP_001941330.1 COG1457: Purine-cytosine permease and related proteins, Pseudomonas aeruginosa YP_001941331.1 COG0583: Transcriptional regulator, Escherichia coli O157:H7 YP_001941332.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001941333.1 COG0531: Amino acid transporters, Pseudomonas aeruginosa YP_001941334.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Mycobacterium tuberculosis CDC1551 YP_001941335.1 COG1012: NAD-dependent aldehyde dehydrogenases, Mesorhizobium loti; KEGG, K00128 YP_001941339.1 COG1680: Beta-lactamase class C and other penicillin binding proteins, Sinorhizobium meliloti; KEGG, K01467 YP_001941340.1 COG0251: Putative translation initiation inhibitor, yjgF family, Pseudomonas aeruginosa YP_001941341.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Mesorhizobium loti; KEGG, K00301 YP_001941342.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Sinorhizobium meliloti YP_001941344.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti YP_001941345.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Sinorhizobium meliloti; KEGG, K02053 YP_001941346.1 COG1176: ABC-type spermidine/putrescine transport system, permease component I, Mesorhizobium loti; KEGG, K02054 YP_001941347.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Mesorhizobium loti; KEGG, K02052 YP_001941348.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Sinorhizobium meliloti YP_001941349.1 COG0583: Transcriptional regulator, Escherichia coli K12 YP_001941350.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa YP_001941351.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Sinorhizobium meliloti YP_001941353.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti YP_001941354.1 COG0583: Transcriptional regulator, Salmonella typhimurium LT2 YP_001941355.1 COG1657: Squalene cyclase, Nostoc sp. PCC 7120; KEGG, K06045 YP_001941356.1 COG1309: Transcriptional regulator, Sinorhizobium meliloti YP_001941359.1 COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase, Brucella melitensis; KEGG, K01714 YP_001941360.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001941362.1 COG1802: Transcriptional regulators, Sinorhizobium meliloti YP_001941364.1 COG5434: Endopolygalacturonase, Ralstonia solanacearum YP_001941365.1 COG1638: TRAP-type C4-dicarboxylate transport system, periplasmic component, Agrobacterium tumefaciens strain C58 YP_001941367.1 COG1593: TRAP-type C4-dicarboxylate transport system, large permease component, Caulobacter vibrioides; DctM protein YP_001941368.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; KEGG, K03762 YP_001941369.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941370.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001941371.1 COG0568: DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32), Ralstonia solanacearum YP_001941374.1 COG4993: Glucose dehydrogenase, Pseudomonas aeruginosa YP_001941375.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Escherichia coli K12 YP_001941376.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum; KEGG, K01259 YP_001941377.1 COG3284: Transcriptional activator of acetoin/glycerol metabolism, Ralstonia solanacearum YP_001941378.1 possibly involved in transport of pyrroloquinoline quinone transport YP_001941379.1 Required in the synthesis of PPQ, but its exact function is unknown YP_001941380.1 KEGG, K06138 YP_001941381.1 COG0535: Predicted Fe-S oxidoreductases, Pseudomonas aeruginosa; KEGG, K06139 YP_001941382.1 COG3569: Topoisomerase IB, Pseudomonas aeruginosa YP_001941383.1 COG1879: ABC-type sugar transport system, periplasmic component, Escherichia coli O157:H7; KEGG, K02058 YP_001941384.1 COG1129: ABC-type sugar transport system, ATPase component, Sinorhizobium meliloti; KEGG, K02056 YP_001941385.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components, Escherichia coli K12; KEGG, K02057 YP_001941386.1 membrane component of a putative sugar ABC transporter system YP_001941387.1 COG1414: Transcriptional regulator, Pseudomonas aeruginosa YP_001941388.1 COG2124: Cytochrome P450, Corynebacterium glutamicum; KEGG, K00517 YP_001941389.1 COG0477: Permeases of the major facilitator superfamily, Sinorhizobium meliloti YP_001941391.1 COG2814: Arabinose efflux permease, Pseudomonas aeruginosa; KEGG, K08159 YP_001941392.1 COG3509: Poly(3-hydroxybutyrate) depolymerase, Ralstonia solanacearum YP_001941393.1 COG4804: Uncharacterized conserved protein, Ralstonia solanacearum YP_001941395.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Mycobacterium tuberculosis H37Rv YP_001941396.1 COG2124: Cytochrome P450, Mesorhizobium loti YP_001941398.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Mycobacterium tuberculosis H37Rv YP_001941401.1 COG1154: Deoxyxylulose-5-phosphate synthase, Ralstonia solanacearum; KEGG, K01662 YP_001941402.1 COG1443: Isopentenyldiphosphate isomerase, Schizosaccharomyces pombe; KEGG, K01823 YP_001941403.1 COG0574: Phosphoenolpyruvate synthase/pyruvate phosphate dikinase, Nostoc sp. PCC 7120; KEGG, K01007 YP_001941404.1 COG4553: Poly-beta-hydroxyalkanoate depolymerase, Ralstonia solanacearum; KEGG, K01066 YP_001941406.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Mycobacterium tuberculosis CDC1551 YP_001941411.1 COG2823: Predicted periplasmic or secreted lipoprotein, Ralstonia solanacearum YP_001941416.1 COG1488: Nicotinic acid phosphoribosyltransferase, Mycobacterium tuberculosis CDC1551; KEGG, K00763 YP_001941417.1 COG2187: Uncharacterized protein conserved in bacteria, Aquifex aeolicus YP_001941418.1 COG0462: Phosphoribosylpyrophosphate synthetase, Fusobacterium nucleatum; KEGG, K00948 YP_001941420.1 COG4986: ABC-type anion transport system, duplicated permease component, Xylella fastidiosa 9a5c; KEGG, K02050 YP_001941421.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Xylella fastidiosa 9a5c; KEGG, K02049 YP_001941423.1 COG0705: Uncharacterized membrane protein (homolog of Drosophila rhomboid), Ralstonia solanacearum YP_001941424.1 COG0517: FOG: CBS domain, Methanopyrus kandleri AV19; contains CBS domains YP_001941425.1 COG2187: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa; KEGG, K07028; conserved in bacteria YP_001941427.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941429.1 COG0071: Molecular chaperone (small heat shock protein), Ralstonia solanacearum YP_001941431.1 COG2823: Predicted periplasmic or secreted lipoprotein, Ralstonia solanacearum YP_001941434.1 COG1611: Predicted Rossmann fold nucleotide-binding protein, Agrobacterium tumefaciens strain C58; KEGG, K06966 YP_001941437.1 COG1064: Zn-dependent alcohol dehydrogenases, Ralstonia solanacearum; KEGG, K00001 YP_001941438.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Ralstonia solanacearum; KEGG, K01420 YP_001941439.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Ralstonia solanacearum; KEGG, K07689; UvrY protein YP_001941440.1 COG4585: Signal transduction histidine kinase, Ralstonia solanacearum YP_001941441.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941442.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941443.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941444.1 COG0282: Acetate kinase, Mesorhizobium loti; KEGG, K00925 YP_001941445.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941447.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00023 YP_001941448.1 COG3243: Poly(3-hydroxyalkanoate) synthetase, Agrobacterium tumefaciens strain C58 YP_001941449.1 COG0280: Phosphotransacetylase, Rickettsia prowazekii; KEGG, K00634 YP_001941450.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Ralstonia solanacearum; KEGG, K00001 YP_001941451.1 COG1236: Predicted exonuclease of the beta-lactamase fold involved in RNA processing, Ralstonia solanacearum; KEGG, K07576 YP_001941453.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001941454.1 KEGG, K02005 YP_001941455.1 COG1136: ABC-type antimicrobial peptide transport system, ATPase component, Caulobacter vibrioides; KEGG, K02003 YP_001941456.1 KEGG, K02004 YP_001941458.1 COG0842: ABC-type multidrug transport system, permease component, Brucella melitensis; KEGG, K01992 YP_001941459.1 COG1131: ABC-type multidrug transport system, ATPase component, Pseudomonas aeruginosa; KEGG, K01990 YP_001941460.1 COG0845: Membrane-fusion protein, Pseudomonas aeruginosa; KEGG, K01993 YP_001941461.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001941463.1 COG2823: Predicted periplasmic or secreted lipoprotein, Ralstonia solanacearum YP_001941465.1 COG0465: ATP-dependent Zn proteases, Nostoc sp. PCC 7120; FtsH protein; KEGG, K03798 YP_001941466.1 class I; catalyzes the formation of deoxyribonucleotides from their corresponding ribonucleotides YP_001941467.1 COG1105: Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB), Mycobacterium tuberculosis CDC1551; KEGG, K00882 YP_001941469.1 COG1306: Uncharacterized conserved protein, Fusobacterium nucleatum YP_001941472.1 COG3876: Uncharacterized protein conserved in bacteria, Bacillus subtilis YP_001941475.1 COG3658: Cytochrome b, Ralstonia solanacearum YP_001941476.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Pseudomonas aeruginosa; KEGG, K07666; QseB protein YP_001941477.1 COG0642: Signal transduction histidine kinase, Pseudomonas aeruginosa; KEGG, K07645 YP_001941479.1 COG2217: Cation transport ATPase, Sinorhizobium meliloti; KEGG, K01533 YP_001941484.1 COG0583: Transcriptional regulator, Vibrio cholerae YP_001941485.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001941486.1 COG3002: Uncharacterized protein conserved in bacteria, Vibrio cholerae YP_001941487.1 COG0415: Deoxyribodipyrimidine photolyase, Caulobacter vibrioides; KEGG, K01669 YP_001941489.1 COG0657: Esterase/lipase, Caulobacter vibrioides YP_001941491.1 COG3046: Uncharacterized protein related to deoxyribodipyrimidine photolyase, Vibrio cholerae; KEGG, K06876; related to deoxyribodipyrimidine photolyase YP_001941492.1 COG3380: Predicted NAD/FAD-dependent oxidoreductase, Pseudomonas aeruginosa; KEGG, K06955 YP_001941493.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti YP_001941495.1 COG2009: Succinate dehydrogenase/fumarate reductase, cytochrome b subunit, Ralstonia solanacearum; KEGG, K00241 YP_001941496.1 COG2142: Succinate dehydrogenase, hydrophobic anchor subunit, Ralstonia solanacearum; KEGG, K00242 YP_001941497.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001941498.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001941499.1 COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog, Mesorhizobium loti; KEGG, K03088 YP_001941500.1 COG0302: GTP cyclohydrolase I, Mycobacterium leprae; KEGG, K01495 YP_001941504.1 COG2230: Cyclopropane fatty acid synthase and related methyltransferases, Caulobacter vibrioides; KEGG, K00574 YP_001941505.1 COG3496: Uncharacterized conserved protein, Agrobacterium tumefaciens strain C58 YP_001941506.1 COG2907: Predicted NAD/FAD-binding protein, Agrobacterium tumefaciens strain C58; KEGG, K06954 YP_001941508.1 COG2230: Cyclopropane fatty acid synthase and related methyltransferases, Caulobacter vibrioides; KEGG, K00574 YP_001941509.1 COG3752: Predicted membrane protein, Mesorhizobium loti YP_001941510.1 Blc protein; COG3040: Bacterial lipocalin, Caulobacter vibrioides; KEGG, K03098 YP_001941511.1 COG2995: Uncharacterized paraquat-inducible protein A, Vibrio cholerae YP_001941512.1 COG3008: Paraquat-inducible protein B, Ralstonia solanacearum YP_001941515.1 KEGG, K00782 YP_001941516.1 COG1139: Uncharacterized conserved protein containing a ferredoxin-like domain, Bacillus halodurans; contains a ferredoxin-like domain YP_001941517.1 COG0247: Fe-S oxidoreductase, Bacillus halodurans YP_001941518.1 COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Pseudomonas aeruginosa; KEGG, K00426 YP_001941519.1 COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Ralstonia solanacearum; KEGG, K00425 YP_001941520.1 ArcA protein; COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Agrobacterium tumefaciens strain C58; KEGG, K07773 YP_001941522.1 COG3047: Outer membrane protein W, Ralstonia solanacearum; KEGG, K07275 YP_001941524.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Methanothermobacter thermautotrophicus YP_001941526.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Escherichia coli K12 YP_001941527.1 COG1309: Transcriptional regulator, Corynebacterium glutamicum YP_001941528.1 COG3009: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001941529.1 COG3008: Paraquat-inducible protein B, Ralstonia solanacearum; KEGG, K06192 YP_001941530.1 COG2995: Uncharacterized paraquat-inducible protein A, Vibrio cholerae; KEGG, K03808 YP_001941531.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001941533.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001941534.1 COG1620: L-lactate permease, Ralstonia solanacearum; KEGG, K03303 YP_001941535.1 COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases, Pseudomonas aeruginosa; KEGG, K00101 YP_001941536.1 COG1802: Transcriptional regulators, Brucella melitensis YP_001941537.1 COG1457: Purine-cytosine permease and related proteins, Pseudomonas aeruginosa YP_001941538.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Staphylococcus aureus N315 YP_001941539.1 COG3318: Predicted metal-binding protein related to the C-terminal domain of SecA, Neisseria meningitidis Z2491; KEGG, K07039 YP_001941543.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001941544.1 IS402 transposase is a fusion between two ORFs, (88-441) and (441-905), as suggested by comparison with other IS5 family members. At position 441, the sequence 5'-CAAAAACTGGGCC-3' is a potential site for a -1 frameshifting. YP_001941545.1 OrfB YP_001941550.1 IS402 transposase is a fusion between two ORFs, (88-441) and (441-905), as suggested by comparison with other IS5 family members. At position 441, the sequence 5'-CAAAAACTGGGCC-3' is a potential site for a -1 frameshifting. YP_001941552.1 COG0479: Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit, Ralstonia solanacearum; KEGG, K00240 YP_001941555.1 COG1814: Uncharacterized membrane protein, Pseudomonas aeruginosa YP_001941557.1 contains response regulator receiver domain YP_001941558.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001941560.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Ralstonia solanacearum YP_001941562.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa; KEGG, K00120 YP_001941564.1 COG1622: Heme/copper-type cytochrome/quinol oxidases, subunit 2, Bacillus halodurans; KEGG, K02275 YP_001941565.1 COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1, Bacillus halodurans; KEGG, K02274 YP_001941566.1 COG2863: Cytochrome c553, Vibrio cholerae YP_001941569.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00023 YP_001941572.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001941573.1 COG0845: Membrane-fusion protein, Pasteurella multocida; KEGG, K01993 YP_001941574.1 COG1131: ABC-type multidrug transport system, ATPase component, Pasteurella multocida; KEGG, K01990 YP_001941575.1 COG0842: ABC-type multidrug transport system, permease component, Pasteurella multocida; KEGG, K01992 YP_001941578.1 catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs YP_001941579.1 COG0282: Acetate kinase, Sinorhizobium meliloti; KEGG, K00925 YP_001941580.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_001941589.1 COG3501: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001941592.1 OrfA YP_001941593.1 OrfB YP_001941597.1 OrfB YP_001941598.1 OrfA YP_001941602.1 COG0431: Predicted flavoprotein, Sinorhizobium meliloti YP_001941603.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Mesorhizobium loti; KEGG, K00537 YP_001941604.1 COG0798: Arsenite efflux pump ACR3 and related permeases, Agrobacterium tumefaciens strain C58; KEGG, K03325 YP_001941605.1 COG0394: Protein-tyrosine-phosphatase, Ralstonia solanacearum; KEGG, K03741 YP_001941606.1 COG0394: Protein-tyrosine-phosphatase, Mesorhizobium loti; KEGG, K01104 YP_001941607.1 COG0346: Lactoylglutathione lyase and related lyases, Mycobacterium tuberculosis CDC1551 YP_001941608.1 COG0640: Predicted transcriptional regulators, Ralstonia solanacearum YP_001941609.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Aeropyrum pernix; KEGG, K08356 YP_001941610.1 COG0723: Rieske Fe-S protein, Aeropyrum pernix; KEGG, K08355 YP_001941615.1 KEGG, K07172 YP_001941616.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_001941620.1 IS402 transposase is a fusion between two ORFs, (88-441) and (441-905), as suggested by comparison with other IS5 family members. At position 441, the sequence 5'-CAAAAACTGGGCC-3' is a potential site for a -1 frameshifting. YP_001941623.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum; CusB protein; KEGG, K07798 YP_001941624.1 COG3696: Putative silver efflux pump, Ralstonia solanacearum; CusA protein; KEGG, K07787 YP_001941628.1 contains internal repeats YP_001941629.1 COG2863: Cytochrome c553, Neisseria meningitidis Z2491 YP_001941630.1 COG3439: Uncharacterized conserved protein, Methanosarcina acetivorans str.C2A YP_001941631.1 KEGG, K08355 YP_001941632.1 KEGG, K08356 YP_001941633.1 KEGG, K02040 YP_001941634.1 COG0640: Predicted transcriptional regulators, Mesorhizobium loti YP_001941635.1 COG0640: Predicted transcriptional regulators, Ralstonia solanacearum YP_001941636.1 COG0394: Protein-tyrosine-phosphatase, Mesorhizobium loti; KEGG, K01104 YP_001941637.1 COG0394: Protein-tyrosine-phosphatase, Ralstonia solanacearum; KEGG, K03741 YP_001941638.1 COG0798: Arsenite efflux pump ACR3 and related permeases, Agrobacterium tumefaciens strain C58; KEGG, K03325 YP_001941639.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Mesorhizobium loti; KEGG, K00537 YP_001941640.1 COG0431: Predicted flavoprotein, Sinorhizobium meliloti YP_001941642.1 COG0003: Oxyanion-translocating ATPase, Listeria innocua; KEGG, K01551 YP_001941644.1 COG2072: Predicted flavoprotein involved in K+ transport, Corynebacterium glutamicum; KEGG, K07222; involved in K+ transport YP_001941650.1 COG2865: Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen, Fusobacterium nucleatum YP_001941652.1 KEGG, K07726 YP_001941654.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001941655.1 OrfB YP_001941656.1 OrfA YP_001941659.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Agrobacterium tumefaciens strain C58 YP_001941662.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001941663.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Pseudomonas aeruginosa; KEGG, K00344 YP_001941664.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Pseudomonas aeruginosa; KEGG, K00540 YP_001941665.1 OrfA YP_001941666.1 OrfB YP_001941667.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Ralstonia solanacearum YP_001941668.1 COG0640: Predicted transcriptional regulators, Pseudomonas aeruginosa; KEGG, K03892 YP_001941669.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Mesorhizobium loti YP_001941670.1 OrfB YP_001941671.1 OrfA YP_001941673.1 COG4221: Short-chain alcohol dehydrogenase of unknown specificity, Nostoc sp. PCC 7120; KEGG, K00540 YP_001941675.1 COG1062: Zn-dependent alcohol dehydrogenases, class III, Escherichia coli O157:H7; KEGG, K00121 YP_001941676.1 COG0346: Lactoylglutathione lyase and related lyases, Vibrio cholerae YP_001941677.1 COG4949: Uncharacterized membrane-anchored protein conserved in bacteria, Mesorhizobium loti YP_001941678.1 OrfB YP_001941679.1 OrfA YP_001941682.1 COG0384: Predicted epimerase, PhzC/PhzF homolog, Corynebacterium glutamicum; KEGG, K06998 YP_001941683.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa YP_001941688.1 TraG protein YP_001941690.1 TrbL protein YP_001941691.1 TrbJ protein YP_001941692.1 COG3451: Type IV secretory pathway, VirB4 components, Mesorhizobium loti; KEGG, K03199; TrbE protein YP_001941693.1 TrbD protein YP_001941695.1 TrbB protein YP_001941696.1 COG3864: Uncharacterized protein conserved in bacteria, Deinococcus radiodurans YP_001941698.1 COG0714: MoxR-like ATPases, Deinococcus radiodurans YP_001941705.1 KEGG, K06077; SlyB protein YP_001941718.1 involved in cell morphogenesis YP_001941722.1 COG0629: Single-stranded DNA-binding protein, Ralstonia solanacearum; KEGG, K03111 YP_001941732.1 OrfB YP_001941733.1 OrfA YP_001941738.1 COG2804: Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB, Aquifex aeolicus YP_001941746.1 KEGG, K03195; TrbI protein YP_001941747.1 KEGG, K03204; TrbG protein YP_001941748.1 TrbF protein YP_001941750.1 COG0178: Excinuclease ATPase subunit, Ralstonia solanacearum; KEGG, K03701 YP_001941751.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Agrobacterium tumefaciens strain C58; KEGG, K00540 YP_001941753.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum YP_001941755.1 COG0517: FOG: CBS domain, Pseudomonas aeruginosa; contains two CBS domains YP_001941757.1 KEGG, K00754 YP_001941760.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_001941761.1 COG0693: Putative intracellular protease/amidase, Pseudomonas aeruginosa YP_001941762.1 COG3268: Uncharacterized conserved protein, Synechocystis YP_001941763.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001941764.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001941765.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001941766.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K03446 YP_001941767.1 COG1566: Multidrug resistance efflux pump, Ralstonia solanacearum; KEGG, K03543 YP_001941769.1 COG3546: Mn-containing catalase, Pseudomonas aeruginosa; KEGG, K07217 YP_001941770.1 COG3685: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001941775.1 COG5478: Predicted small integral membrane protein, Pseudomonas aeruginosa YP_001941777.1 COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Ralstonia solanacearum; KEGG, K00426 YP_001941778.1 COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Ralstonia solanacearum; KEGG, K00425 YP_001941780.1 COG2303: Choline dehydrogenase and related flavoproteins, Halobacterium sp. NRC-1 YP_001941783.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Sinorhizobium meliloti; KEGG, K01781 YP_001941784.1 COG0028: Thiamine pyrophosphate-requiring enzymes YP_001941785.1 COG3387: Glucoamylase and related glycosyl hydrolases, Ralstonia solanacearum YP_001941786.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Nostoc sp. PCC 7120 YP_001941787.1 COG1622: Heme/copper-type cytochrome/quinol oxidases, subunit 2, Sinorhizobium meliloti; KEGG, K02275 YP_001941788.1 COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1, Mesorhizobium loti; CyoB2 protein YP_001941789.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001941791.1 COG1285: Uncharacterized membrane protein, Yersinia pestis; KEGG, K07507 YP_001941793.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Sinorhizobium meliloti YP_001941794.1 COG3568: Metal-dependent hydrolase, Brucella melitensis YP_001941796.1 COG0366: Glycosidases, Ralstonia solanacearum YP_001941797.1 COG0366: Glycosidases, Ralstonia solanacearum; KEGG, K05343 YP_001941798.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001941799.1 COG1523: Type II secretory pathway, pullulanase PulA and related glycosidases, Ralstonia solanacearum; GlgX protein; KEGG, K02438 YP_001941800.1 COG0296: 1,4-alpha-glucan branching enzyme, Ralstonia solanacearum; KEGG, K01236 YP_001941801.1 COG1640: 4-alpha-glucanotransferase, Ralstonia solanacearum; KEGG, K00705 YP_001941802.1 COG3280: Maltooligosyl trehalose synthase, Ralstonia solanacearum; KEGG, K06044 YP_001941804.1 KEGG, K01613 YP_001941807.1 COG0693: Putative intracellular protease/amidase, Pseudomonas aeruginosa; KEGG, K05520 YP_001941811.1 COG0025: NhaP-type Na+/H+ and K+/H+ antiporters, Pseudomonas aeruginosa YP_001941812.1 COG1793: ATP-dependent DNA ligase, Agrobacterium tumefaciens strain C58 YP_001941813.1 COG1273: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001941817.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001941818.1 COG3685: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001941823.1 COG0517: FOG: CBS domain, Pseudomonas aeruginosa; contains CBS domains YP_001941826.1 KEGG, K02334 YP_001941827.1 COG1914: Mn2+ and Fe2+ transporters of the NRAMP family, Sinorhizobium meliloti YP_001941828.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Sinorhizobium meliloti; KEGG, K00121 YP_001941830.1 COG3652: Predicted outer membrane protein, Pseudomonas aeruginosa; KEGG, K08995 YP_001941831.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Nostoc sp. PCC 7120; KEGG, K00540 YP_001941834.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Bacillus subtilis YP_001941836.1 COG0438: Glycosyltransferase, Nostoc sp. PCC 7120 YP_001941837.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Xylella fastidiosa 9a5c; KEGG, K01710 YP_001941838.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936; contains a signal receiver domain YP_001941841.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001941842.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001941844.1 COG0859: ADP-heptose:LPS heptosyltransferase, Neisseria meningitidis Z2491 YP_001941845.1 involved in cell wall biogenesis YP_001941846.1 COG2192: Predicted carbamoyl transferase, NodU family, Ralstonia solanacearum; KEGG, K00612 YP_001941847.1 COG0859: ADP-heptose:LPS heptosyltransferase, Mesorhizobium loti YP_001941848.1 COG0241: Histidinol phosphatase and related phosphatases, Escherichia coli O157:H7; KEGG, K03273 YP_001941849.1 COG4221: Short-chain alcohol dehydrogenase of unknown specificity, Halobacterium sp. NRC-1 YP_001941851.1 COG5265: ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components, Ralstonia solanacearum; KEGG, K06147 YP_001941855.1 COG1145: Ferredoxin, Salmonella typhimurium LT2 YP_001941856.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Nostoc sp. PCC 7120; KEGG, K00001 YP_001941857.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Ralstonia solanacearum; KEGG, K02053 YP_001941858.1 COG1176: ABC-type spermidine/putrescine transport system, permease component I, Ralstonia solanacearum; KEGG, K02054 YP_001941859.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Ralstonia solanacearum; KEGG, K02055 YP_001941860.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Ralstonia solanacearum; KEGG, K02052 YP_001941861.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00375; contains aminotransferase domain YP_001941862.1 COG0160: 4-aminobutyrate aminotransferase and related aminotransferases, Sinorhizobium meliloti YP_001941863.1 COG2334: Putative homoserine kinase type II (protein kinase fold), Mesorhizobium loti YP_001941866.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Corynebacterium glutamicum; KEGG, K08232 YP_001941867.1 Catalyzes the reversible two-electron oxidation of formate to carbon dioxide. It allows the assimilation of carbon dioxide and provides energy for growth through oxidative phosphorylation coupled to the reduction of oxygen, nitrate, sulphate or fumarate YP_001941868.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00825 YP_001941873.1 COG2837: Predicted iron-dependent peroxidase, Mycobacterium tuberculosis CDC1551; KEGG, K07223 YP_001941874.1 COG1659: Uncharacterized protein, linocin/CFP29 homolog, Mycobacterium tuberculosis CDC1551 YP_001941876.1 COG0542: ATPases with chaperone activity, ATP-binding subunit, Pseudomonas aeruginosa; ClpC protein; KEGG, K03696 YP_001941877.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Caulobacter vibrioides; KEGG, K00122 YP_001941878.1 COG1457: Purine-cytosine permease and related proteins, Bacillus subtilis YP_001941879.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001941880.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001941881.1 COG3342: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001941882.1 COG0251: Putative translation initiation inhibitor, yjgF family, Pseudomonas aeruginosa YP_001941883.1 COG2072: Predicted flavoprotein involved in K+ transport, Pseudomonas aeruginosa; KEGG, K07222; involved in K+ transport YP_001941885.1 COG3781: Predicted membrane protein, Ralstonia solanacearum; KEGG, K08994 YP_001941886.1 COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Pseudomonas aeruginosa; KEGG, K00426 YP_001941887.1 COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Salmonella typhimurium LT2; KEGG, K00425 YP_001941888.1 COG1526: Uncharacterized protein required for formate dehydrogenase activity, Ralstonia solanacearum; KEGG, K02379 YP_001941889.1 COG0303: Molybdopterin biosynthesis enzyme, Pseudomonas aeruginosa; KEGG, K03750; MoeA protein YP_001941890.1 COG2896: Molybdenum cofactor biosynthesis enzyme, Ralstonia solanacearum; KEGG, K03639 YP_001941891.1 COG0314: Molybdopterin converting factor, large subunit, Ralstonia solanacearum; KEGG, K03635 YP_001941894.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa YP_001941895.1 COG1396: Predicted transcriptional regulators, Ralstonia solanacearum YP_001941896.1 COG3550: Uncharacterized protein related to capsule biosynthesis enzymes, Escherichia coli K12; related to capsule biosynthesis enzymes YP_001941897.1 involved in cell division YP_001941898.1 COG0582: Integrase, Ralstonia solanacearum YP_001941899.1 COG2223: Nitrate/nitrite transporter, Ralstonia solanacearum; KEGG, K02575 YP_001941900.1 COG0760: Parvulin-like peptidyl-prolyl isomerase, Brucella melitensis; KEGG, K03769 YP_001941901.1 COG2181: Nitrate reductase gamma subunit, Brucella melitensis; KEGG, K00374 YP_001941902.1 COG2180: Nitrate reductase delta subunit, Salmonella typhimurium LT2; KEGG, K00373 YP_001941903.1 COG1140: Nitrate reductase beta subunit, Brucella melitensis; KEGG, K00371 YP_001941904.1 COG5013: Nitrate reductase alpha subunit, Salmonella typhimurium LT2; KEGG, K00370 YP_001941906.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001941907.1 COG3971: 2-keto-4-pentenoate hydratase, Agrobacterium tumefaciens strain C58 YP_001941909.1 COG0798: Arsenite efflux pump ACR3 and related permeases, Agrobacterium tumefaciens strain C58; KEGG, K03325 YP_001941910.1 COG0394: Protein-tyrosine-phosphatase, Mesorhizobium loti; KEGG, K03741 YP_001941911.1 COG0640: Predicted transcriptional regulators, Ralstonia solanacearum YP_001941912.1 COG0828: Ribosomal protein S21, Ralstonia solanacearum; KEGG, K02970 YP_001941916.1 COG3832: Uncharacterized conserved protein, Mesorhizobium loti YP_001941917.1 COG0640: Predicted transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001941918.1 COG2017: Galactose mutarotase and related enzymes, Caulobacter vibrioides; KEGG, K01785 YP_001941919.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2 YP_001941920.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Agrobacterium tumefaciens strain C58 YP_001941921.1 COG1250: 3-hydroxyacyl-CoA dehydrogenase, Ralstonia solanacearum; KEGG, K00074 YP_001941922.1 catalyzes the formation of beta-ketovaleryl-CoA from acetyl-CoA and propionyl-CoA YP_001941923.1 COG0644: Dehydrogenases (flavoproteins), Ralstonia solanacearum; KEGG, K00311 YP_001941924.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001941925.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001941926.1 COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, Neisseria meningitidis MC58; KEGG, K01897 YP_001941927.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001941928.1 COG0642: Signal transduction histidine kinase, Bacillus subtilis YP_001941929.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Thermotoga maritima; KEGG, K07668; VicR protein YP_001941930.1 COG0229: Conserved domain frequently associated with peptide methionine sulfoxide reductase, Mesorhizobium loti; KEGG, K07305 YP_001941931.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Sinorhizobium meliloti; contains transmembrane domain YP_001941932.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_001941933.1 KEGG, K03461 YP_001941934.1 catalyzes the hydrolytic cleavage of hydantoin with aromatic side chains at the 5'position YP_001941935.1 COG1953: Cytosine/uracil/thiamine/allantoin permeases, Ralstonia solanacearum; KEGG, K03457 YP_001941936.1 catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines YP_001941937.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001941938.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001941939.1 COG1309: Transcriptional regulator, Pseudomonas aeruginosa; KEGG, K09017 YP_001941940.1 COG0183: Acetyl-CoA acetyltransferase, Brucella melitensis; KEGG, K00626 YP_001941941.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Brucella melitensis; KEGG, K00022 YP_001941942.1 COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, Brucella melitensis; KEGG, K01895 YP_001941943.1 COG2207: AraC-type DNA-binding domain-containing proteins, Brucella melitensis YP_001941945.1 contains chaperone activity YP_001941947.1 KEGG, K01139 YP_001941948.1 COG4717: Uncharacterized conserved protein, Sinorhizobium meliloti YP_001941949.1 COG0420: DNA repair exonuclease, Sinorhizobium meliloti YP_001941951.1 COG0405: Gamma-glutamyltransferase, Mycobacterium tuberculosis CDC1551; KEGG, K00681 YP_001941956.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Pseudomonas aeruginosa YP_001941957.1 repA5 protein YP_001941961.1 COG3240: Phospholipase/lecithinase/hemolysin, Ralstonia solanacearum YP_001941966.1 OrfA YP_001941968.1 COG1651: Protein-disulfide isomerase, Ralstonia solanacearum; DsbC protein; KEGG, K03981 YP_001941970.1 TraW protein YP_001941971.1 TraU protein YP_001941972.1 TrbC protein YP_001941973.1 TraE protein YP_001941974.1 TraK protein YP_001941975.1 TraB protein YP_001941977.1 COG3451: Type IV secretory pathway, VirB4 components, Salmonella typhimurium LT2; TraC protein YP_001941978.1 TrhF protein YP_001941979.1 TraF protein YP_001941980.1 TraH protein YP_001941981.1 TraG protein YP_001941983.1 KEGG, K02669; PilT protein YP_001941986.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_001941988.1 COG3501: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001941990.1 COG3209: Rhs family protein, Salmonella typhimurium LT2 YP_001941992.1 OrfB YP_001941993.1 OrfA YP_001941995.1 COG3505: Type IV secretory pathway, VirD4 components, Salmonella typhimurium LT2; TraD protein YP_001942006.1 COG1475: Predicted transcriptional regulators, Mesorhizobium loti YP_001942011.1 OrfB YP_001942012.1 OrfA YP_001942021.1 COG0428: Predicted divalent heavy-metal cations transporter, Mycobacterium tuberculosis CDC1551 YP_001942024.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001942027.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; CusS protein; KEGG, K07644 YP_001942028.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; CusR protein; KEGG, K07665 YP_001942029.1 COG3696: Putative silver efflux pump, Ralstonia solanacearum; KEGG, K07239 YP_001942030.1 COG0845: Membrane-fusion protein, Pseudomonas aeruginosa; CzcB protein YP_001942031.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001942032.1 COG2217: Cation transport ATPase, Caulobacter vibrioides YP_001942033.1 COG0640: Predicted transcriptional regulators, Ralstonia solanacearum YP_001942034.1 COG0346: Lactoylglutathione lyase and related lyases, Mycobacterium tuberculosis CDC1551 YP_001942035.1 COG0394: Protein-tyrosine-phosphatase, Mesorhizobium loti; KEGG, K01104 YP_001942036.1 COG0394: Protein-tyrosine-phosphatase, Ralstonia solanacearum; KEGG, K03741 YP_001942037.1 COG0798: Arsenite efflux pump ACR3 and related permeases, Agrobacterium tumefaciens strain C58; KEGG, K03325 YP_001942038.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001942039.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Mesorhizobium loti; KEGG, K00537 YP_001942040.1 COG0431: Predicted flavoprotein, Sinorhizobium meliloti YP_001942042.1 COG3544: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001942043.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; CusS protein; KEGG, K07644 YP_001942044.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K02483 YP_001942047.1 COG1538: Outer membrane protein, Agrobacterium tumefaciens strain C58 YP_001942048.1 COG2132: Putative multicopper oxidases, Sinorhizobium meliloti; KEGG, K00423 YP_001942050.1 KEGG, K07156 YP_001942051.1 KEGG, K07245 YP_001942053.1 COG1145: Ferredoxin, Bacillus subtilis YP_001942056.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum; CusB protein; KEGG, K07798 YP_001942057.1 COG3696: Putative silver efflux pump, Ralstonia solanacearum; CusA protein; KEGG, K07787 YP_001942059.1 COG4232: Thiol:disulfide interchange protein, Ralstonia solanacearum; DsbD protein; KEGG, K04084 YP_001942070.1 COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair, Ralstonia solanacearum; involved in DNA repair YP_001942071.1 COG0587: DNA polymerase III, alpha subunit, Ralstonia solanacearum; KEGG, K00961 YP_001942073.1 COG5534: Plasmid replication initiator protein, Ralstonia solanacearum YP_001942076.1 COG1192: ATPases involved in chromosome partitioning, Xylella fastidiosa 9a5c; ParA protein YP_001942080.1 COG0582: Integrase, Ralstonia solanacearum YP_001942084.1 COG1487: Predicted nucleic acid-binding protein, contains PIN domain, Sinorhizobium meliloti; KEGG, K07062 YP_001942086.1 ParA5 protein YP_001942087.1 ParB5 protein YP_001944522.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_001944524.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_001944525.1 COG0776: Bacterial nucleoid DNA-binding protein, Ralstonia solanacearum; KEGG, K03530 YP_001944526.1 COG0523: Putative GTPases (G3E family), Ralstonia solanacearum YP_001944527.1 COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains), Ralstonia solanacearum YP_001944528.1 COG1450: Type II secretory pathway, component PulD, Ralstonia solanacearum; KEGG, K02453 YP_001944529.1 COG2804: Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB, Ralstonia solanacearum; KEGG, K02454 YP_001944530.1 COG1459: Type II secretory pathway, component PulF, Ralstonia solanacearum; KEGG, K02455 YP_001944531.1 KEGG, K02452 YP_001944532.1 COG2165: Type II secretory pathway, pseudopilin PulG, Ralstonia solanacearum; KEGG, K02456 YP_001944533.1 COG2165: Type II secretory pathway, pseudopilin PulG, Ralstonia solanacearum; KEGG, K02457 YP_001944534.1 COG2165: Type II secretory pathway, pseudopilin PulG, Ralstonia solanacearum; KEGG, K02458 YP_001944535.1 KEGG, K02459 YP_001944536.1 COG3156: Type II secretory pathway, component PulK, Ralstonia solanacearum; KEGG, K02460 YP_001944537.1 KEGG, K02461 YP_001944538.1 COG3149: Type II secretory pathway, component PulM, Ralstonia solanacearum; KEGG, K02462 YP_001944539.1 KEGG, K02463 YP_001944540.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001944542.1 COG1846: Transcriptional regulators, Ralstonia solanacearum; KEGG, K03712 YP_001944543.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli O157:H7; KEGG, K03446 YP_001944544.1 COG0583: Transcriptional regulator, Salmonella typhimurium LT2 YP_001944545.1 COG1380: Putative effector of murein hydrolase LrgA, Pseudomonas aeruginosa; KEGG, K06518 YP_001944546.1 COG1346: Putative effector of murein hydrolase, Vibrio cholerae YP_001944547.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001944548.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001944549.1 COG1886: Flagellar motor switch/type III secretory pathway protein, Ralstonia solanacearum; FliN protein; KEGG, K02417 YP_001944550.1 FliO protein; KEGG, K02418 YP_001944551.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001944552.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_001944553.1 COG1684: Flagellar biosynthesis pathway, component FliR, Yersinia pestis; FliR protein; KEGG, K02421 YP_001944555.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components, Ralstonia solanacearum; KEGG, K02051 YP_001944556.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Mesorhizobium loti; KEGG, K02049 YP_001944557.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component, Mesorhizobium loti; KEGG, K02050 YP_001944558.1 COG0642: Signal transduction histidine kinase, Mesorhizobium loti YP_001944559.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum YP_001944560.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001944561.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Ralstonia solanacearum YP_001944562.1 COG2189: Adenine specific DNA methylase Mod, Listeria innocua; KEGG, K07316 YP_001944563.1 COG3587: Restriction endonuclease, Fusobacterium nucleatum; KEGG, K01156 YP_001944567.1 COG4301: Uncharacterized conserved protein, Nostoc sp. PCC 7120 YP_001944568.1 COG1262: Uncharacterized conserved protein, Ralstonia solanacearum YP_001944570.1 COG2128: Uncharacterized conserved protein, Sinorhizobium meliloti YP_001944571.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001944572.1 OrfA YP_001944580.1 COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog, Mesorhizobium loti; KEGG, K03088 YP_001944581.1 COG0753: Catalase, Helicobacter pylori 26695; KEGG, K00429 YP_001944583.1 COG4127: Uncharacterized conserved protein, Caulobacter vibrioides YP_001944584.1 negatively supercoils closed circular double-stranded DNA YP_001944585.1 binds the polymerase to DNA and acts as a sliding clamp YP_001944586.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001944587.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_001944588.1 COG0594: RNase P protein component, Ralstonia solanacearum; KEGG, K01164 YP_001944589.1 COG0759: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K08998 YP_001944590.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_001944592.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001944596.1 COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Listeria innocua; KEGG, K00657 YP_001944598.1 COG4681: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944599.1 COG0346: Lactoylglutathione lyase and related lyases, Pseudomonas aeruginosa YP_001944600.1 COG0350: Methylated DNA-protein cysteine methyltransferase, Ralstonia solanacearum; KEGG, K00567 YP_001944601.1 COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase, Pseudomonas aeruginosa; KEGG, K01247 YP_001944602.1 involved in the first step of glutathione biosynthesis YP_001944604.1 COG1620: L-lactate permease, Bacillus subtilis; KEGG, K03303 YP_001944605.1 COG1802: Transcriptional regulators, Deinococcus radiodurans YP_001944606.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa; KEGG, K00301 YP_001944607.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_001944608.1 COG1178: ABC-type Fe3+ transport system, permease component, Sinorhizobium meliloti; KEGG, K02011 YP_001944609.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Sinorhizobium meliloti; KEGG, K02052 YP_001944610.1 COG1840: ABC-type Fe3+ transport system, periplasmic component, Sinorhizobium meliloti; KEGG, K02012 YP_001944611.1 COG1524: Uncharacterized proteins of the AP superfamily, Sinorhizobium meliloti YP_001944612.1 COG1012: NAD-dependent aldehyde dehydrogenases, Sinorhizobium meliloti; KEGG, K00131 YP_001944616.1 COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058 YP_001944617.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001944618.1 decatenates replicating daughter chromosomes YP_001944619.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum YP_001944620.1 COG0758: Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake, Ralstonia solanacearum; KEGG, K04096 YP_001944621.1 COG0242: N-formylmethionyl-tRNA deformylase, Ralstonia solanacearum; KEGG, K01462 YP_001944622.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_001944623.1 COG1280: Putative threonine efflux protein, Ralstonia solanacearum YP_001944624.1 COG0501: Zn-dependent protease with chaperone function, Ralstonia solanacearum; HtpX protein; KEGG, K03799 YP_001944625.1 COG0144: tRNA and rRNA cytosine-C5-methylases, Ralstonia solanacearum; KEGG, K03500 YP_001944627.1 COG5000: Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation, Ralstonia solanacearum; KEGG, K00936 YP_001944628.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum; KEGG, K05971 YP_001944629.1 COG0603: Predicted PP-loop superfamily ATPase, Caulobacter vibrioides; KEGG, K06920 YP_001944630.1 COG0602: Organic radical activating enzymes, Ralstonia solanacearum YP_001944631.1 COG0720: 6-pyruvoyl-tetrahydropterin synthase, Ralstonia solanacearum; KEGG, K01737 YP_001944632.1 COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, Sinorhizobium meliloti; KEGG, K01630 YP_001944633.1 COG0790: FOG: TPR repeat, SEL1 subfamily, Ralstonia solanacearum; KEGG, K07126; contains TRP repeat YP_001944634.1 COG0772: Bacterial cell division membrane protein, Ralstonia solanacearum; KEGG, K05837; RodA protein YP_001944635.1 COG0768: Cell division protein FtsI/penicillin-binding protein 2, Ralstonia solanacearum; KEGG, K05515 YP_001944636.1 COG2891: Cell shape-determining protein, Ralstonia solanacearum; KEGG, K03571; MreD protein YP_001944637.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001944638.1 functions in MreBCD complex in some organisms YP_001944639.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001944640.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001944641.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001944642.1 COG2326: Uncharacterized conserved protein, Ralstonia solanacearum YP_001944643.1 COG0708: Exonuclease III, Ralstonia solanacearum; KEGG, K01142 YP_001944644.1 COG1064: Zn-dependent alcohol dehydrogenases, Xylella fastidiosa 9a5c; KEGG, K00002 YP_001944645.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001944646.1 COG0501: Zn-dependent protease with chaperone function, Ralstonia solanacearum; contains chaperone function YP_001944647.1 AmpG protein; COG0477: Permeases of the major facilitator superfamily, Neisseria meningitidis MC58; KEGG, K08218 YP_001944648.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum; MetW protein YP_001944649.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_001944650.1 COG3468: Type V secretory pathway, adhesin AidA, Escherichia coli O157:H7 YP_001944651.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001944652.1 COG1011: Predicted hydrolase (HAD superfamily), Ralstonia solanacearum; KEGG, K07025 YP_001944653.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001944655.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936 YP_001944656.1 COG4567: Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain, Ralstonia solanacearum YP_001944658.1 heat shock protein involved in degradation of misfolded proteins YP_001944659.1 heat shock protein involved in degradation of misfolded proteins YP_001944660.1 COG1734: DnaK suppressor protein, Ralstonia solanacearum; KEGG, K06204 YP_001944661.1 COG0523: Putative GTPases (G3E family), Ralstonia solanacearum YP_001944662.1 COG1092: Predicted SAM-dependent methyltransferases, Ralstonia solanacearum; KEGG, K06969 YP_001944663.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001944664.1 COG3159: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944665.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001944666.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_001944667.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001944669.1 COG5285: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin, Ralstonia solanacearum; KEGG, K00477 YP_001944671.1 COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases), Escherichia coli O157:H7; KEGG, K05882 YP_001944673.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Pseudomonas aeruginosa YP_001944675.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001944676.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00154 YP_001944678.1 COG2303: Choline dehydrogenase and related flavoproteins, Ralstonia solanacearum; KEGG, K00108 YP_001944679.1 COG3144: Flagellar hook-length control protein, Ralstonia solanacearum; FliK protein; KEGG, K02414 YP_001944680.1 COG2882: Flagellar biosynthesis chaperone, Ralstonia solanacearum; KEGG, K02413 YP_001944681.1 COG1157: Flagellar biosynthesis/type III secretory pathway ATPase, Salmonella typhimurium LT2; KEGG, K02412 YP_001944682.1 binds to and inhibits the function of flagella specific ATPase FliI YP_001944683.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001944684.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001944685.1 COG1677: Flagellar hook-basal body protein, Yersinia pestis; FliE protein; KEGG, K02408 YP_001944686.1 COG1516: Flagellin-specific chaperone FliS, Yersinia pestis; FliS protein; KEGG, K02422 YP_001944687.1 FliT protein; KEGG, K02423 YP_001944689.1 KEGG, K04061 YP_001944690.1 COG3295: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944691.1 COG1975: Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family, Ralstonia solanacearum; KEGG, K07402 YP_001944692.1 COG0531: Amino acid transporters, Ralstonia solanacearum; KEGG, K03294 YP_001944693.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Ralstonia solanacearum YP_001944695.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Neisseria meningitidis Z2491; KEGG, K00528 YP_001944696.1 COG3568: Metal-dependent hydrolase, Salmonella typhimurium LT2; KEGG, K06896 YP_001944698.1 COG0778: Nitroreductase, Ralstonia solanacearum YP_001944700.1 COG0579: Predicted dehydrogenase, Mesorhizobium loti; KEGG, K00301 YP_001944702.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001944703.1 COG0747: ABC-type dipeptide transport system, periplasmic component, Pseudomonas aeruginosa; KEGG, K02035 YP_001944704.1 COG0601: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components, Pseudomonas aeruginosa; KEGG, K02033 YP_001944705.1 COG1173: ABC-type dipeptide/oligopeptide/nickel transport systems, permease components, Pseudomonas aeruginosa; KEGG, K02034 YP_001944706.1 COG0444: ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component, Pseudomonas aeruginosa; KEGG, K02031 YP_001944707.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_001944709.1 COG1540: Uncharacterized proteins, homologs of lactam utilization protein B, Ralstonia solanacearum; KEGG, K07160 YP_001944710.1 COG1984: Allophanate hydrolase subunit 2, Ralstonia solanacearum; KEGG, K01457 YP_001944711.1 COG2049: Allophanate hydrolase subunit 1, Ralstonia solanacearum; KEGG, K06351 YP_001944712.1 COG5631: Predicted transcription regulator, contains HTH domain (MarR family), Ralstonia solanacearum; contains HTH domain YP_001944713.1 COG0212: 5-formyltetrahydrofolate cyclo-ligase, Ralstonia solanacearum YP_001944714.1 COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains), Ralstonia solanacearum; KEGG, K08309 YP_001944715.1 COG0702: Predicted nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K00329 YP_001944716.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K04097 YP_001944717.1 catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases YP_001944718.1 COG1396: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001944719.1 COG0006: Xaa-Pro aminopeptidase, Caulobacter vibrioides; KEGG, K01262 YP_001944720.1 FlgN protein; KEGG, K02399 YP_001944721.1 FlgM protein; KEGG, K02398 YP_001944722.1 required for the assembly of the flagellar basal body P-ring YP_001944723.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001944724.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001944725.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001944726.1 the hook connects flagellar basal body to the flagellar filament YP_001944727.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001944728.1 makes up the distal portion of the flagellar basal body rod YP_001944729.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Burkholderia thailandensis has 2 copies of this and other flagella genes YP_001944730.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001944731.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001944732.1 COG5581: Predicted glycosyltransferase, Yersinia pestis YP_001944733.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_001944734.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001944735.1 COG2233: Xanthine/uracil permeases, Escherichia coli K12; KEGG, K02824 YP_001944736.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001944737.1 COG2059: Chromate transport protein ChrA, Ralstonia solanacearum; KEGG, K07240 YP_001944738.1 COG2059: Chromate transport protein ChrA, Ralstonia solanacearum; KEGG, K07240 YP_001944740.1 COG3619: Predicted membrane protein, Methanosarcina acetivorans str.C2A YP_001944741.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001944743.1 COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes, Caulobacter vibrioides; KEGG, K00383 YP_001944744.1 COG1462: Uncharacterized protein involved in formation of curli polymers, Pseudomonas aeruginosa YP_001944745.1 COG4259: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001944746.1 COG4380: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944747.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa; KEGG, K09471 YP_001944748.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa; KEGG, K00540 YP_001944750.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Escherichia coli K12; KEGG, K02053 YP_001944751.1 COG1176: ABC-type spermidine/putrescine transport system, permease component I, Pseudomonas aeruginosa; KEGG, K02054 YP_001944752.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Neisseria meningitidis Z2491; KEGG, K02052 YP_001944753.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Pseudomonas aeruginosa; KEGG, K02055 YP_001944754.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Pseudomonas aeruginosa; KEGG, K00833 YP_001944755.1 COG0174: Glutamine synthetase, Caulobacter vibrioides; KEGG, K01915 YP_001944756.1 COG2071: Predicted glutamine amidotransferases, Pseudomonas aeruginosa; KEGG, K07010 YP_001944758.1 COG1396: Predicted transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001944759.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K09472 YP_001944762.1 COG0672: High-affinity Fe2+/Pb2+ permease, Rickettsia prowazekii; KEGG, K07243 YP_001944765.1 COG4737: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944766.1 COG2944: Predicted transcriptional regulator, Ralstonia solanacearum; KEGG, K07726 YP_001944767.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001944768.1 COG1207: N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains), Ralstonia solanacearum; KEGG, K00972 YP_001944769.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001944770.1 COG1539: Dihydroneopterin aldolase, Ralstonia solanacearum; KEGG, K01633 YP_001944771.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum YP_001944772.1 COG1565: Uncharacterized conserved protein, Ralstonia solanacearum YP_001944775.1 COG0524: Sugar kinases, ribokinase family, Deinococcus radiodurans; KEGG, K00847 YP_001944776.1 COG2942: N-acyl-D-glucosamine 2-epimerase, Xylella fastidiosa 9a5c YP_001944777.1 COG1609: Transcriptional regulators, Caulobacter vibrioides YP_001944780.1 COG0385: Predicted Na+-dependent transporter, Pseudomonas aeruginosa YP_001944782.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001944783.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001944784.1 COG2070: Dioxygenases related to 2-nitropropane dioxygenase, Ralstonia solanacearum; KEGG, K00459 YP_001944785.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum; KEGG, K01561 YP_001944786.1 COG1522: Transcriptional regulators, Mesorhizobium loti; KEGG, K03719 YP_001944787.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Sinorhizobium meliloti YP_001944788.1 KEGG, K06938 YP_001944789.1 COG2606: Uncharacterized conserved protein, Ralstonia solanacearum YP_001944790.1 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA YP_001944791.1 COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058 YP_001944792.1 COG3565: Predicted dioxygenase of extradiol dioxygenase family, Pseudomonas aeruginosa; KEGG, K06991 YP_001944793.1 COG3545: Predicted esterase of the alpha/beta hydrolase fold, Ralstonia solanacearum; KEGG, K07002 YP_001944794.1 COG3511: Phospholipase C, Ralstonia solanacearum; KEGG, K01114 YP_001944796.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Sinorhizobium meliloti; KEGG, K03518 YP_001944797.1 COG1319: Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs, Sinorhizobium meliloti; CoxM protein YP_001944798.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Sinorhizobium meliloti YP_001944799.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001944800.1 COG0625: Glutathione S-transferase, Sinorhizobium meliloti; KEGG, K00799 YP_001944801.1 COG4774: Outer membrane receptor for monomeric catechols, Pseudomonas aeruginosa YP_001944802.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001944803.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001944804.1 COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase, Ralstonia solanacearum; KEGG, K01714 YP_001944805.1 COG1613: ABC-type sulfate transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02048 YP_001944806.1 OrfB YP_001944807.1 OrfA YP_001944808.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K00799 YP_001944811.1 COG3455: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944812.1 COG3522: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944813.1 COG3521: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944815.1 COG3516: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944816.1 COG3517: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944817.1 COG3157: Hemolysin-coregulated protein (uncharacterized), Ralstonia solanacearum; KEGG, K06887 YP_001944818.1 COG3518: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944819.1 COG3519: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944820.1 COG3520: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944821.1 COG0542: ATPases with chaperone activity, ATP-binding subunit, Ralstonia solanacearum YP_001944822.1 COG3515: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944823.1 COG3501: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944835.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum; KEGG, K03286 YP_001944836.1 COG3913: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944839.1 COG0598: Mg2+ and Co2+ transporters, Pseudomonas aeruginosa; KEGG, K03284 YP_001944840.1 COG0308: Aminopeptidase N, Ralstonia solanacearum; KEGG, K01256 YP_001944843.1 COG2890: Methylase of polypeptide chain release factors, Ralstonia solanacearum YP_001944844.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum YP_001944845.1 COG3310: Uncharacterized protein conserved in bacteria, Xylella fastidiosa 9a5c YP_001944846.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001944847.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001944848.1 COG0778: Nitroreductase, Sinorhizobium meliloti YP_001944849.1 COG0443: Molecular chaperone, Ralstonia solanacearum; KEGG, K04046 YP_001944850.1 COG1278: Cold shock proteins, Ralstonia solanacearum; KEGG, K03704 YP_001944851.1 COG0531: Amino acid transporters, Ralstonia solanacearum YP_001944852.1 COG3384: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001944853.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_001944854.1 COG0278: Glutaredoxin-related protein, Ralstonia solanacearum; KEGG, K07390 YP_001944855.1 COG2890: Methylase of polypeptide chain release factors, Ralstonia solanacearum; KEGG, K02493 YP_001944856.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001944857.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001944858.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Caulobacter vibrioides YP_001944860.1 COG0006: Xaa-Pro aminopeptidase, Neisseria meningitidis Z2491; KEGG, K01262 YP_001944861.1 KEGG, K05993 YP_001944862.1 COG1011: Predicted hydrolase (HAD superfamily), Sinorhizobium meliloti; KEGG, K01560 YP_001944863.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001944865.1 COG0583: Transcriptional regulator, Mesorhizobium loti; KEGG, K03566 YP_001944866.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001944867.1 COG3801: Uncharacterized protein conserved in bacteria, Caulobacter vibrioides YP_001944868.1 COG1113: Gamma-aminobutyrate permease and related permeases, Pseudomonas aeruginosa; KEGG, K03293 YP_001944869.1 COG2850: Uncharacterized conserved protein, Neisseria meningitidis MC58 YP_001944870.1 COG4757: Predicted alpha/beta hydrolase, Ralstonia solanacearum YP_001944872.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001944873.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K03185 YP_001944874.1 COG1651: Protein-disulfide isomerase, Ralstonia solanacearum; DsbC protein; KEGG, K03981 YP_001944875.1 COG3975: Predicted protease with the C-terminal PDZ domain, Ralstonia solanacearum YP_001944876.1 COG1182: Acyl carrier protein phosphodiesterase, Pseudomonas aeruginosa; KEGG, K01118 YP_001944877.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001944878.1 COG3025: Uncharacterized conserved protein, Ralstonia solanacearum YP_001944879.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001944880.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001944881.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001944882.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001944883.1 COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091 YP_001944884.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_001944885.1 protein associated with Co2+ and Mg2+ efflux YP_001944886.1 COG2821: Membrane-bound lytic murein transglycosylase, Ralstonia solanacearum; KEGG, K08304 YP_001944887.1 COG1541: Coenzyme F390 synthetase, Ralstonia solanacearum; KEGG, K01912 YP_001944888.1 COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism, Ralstonia solanacearum; KEGG, K02614 YP_001944889.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001944890.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001944891.1 KEGG, K00128 YP_001944892.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001944893.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Ralstonia solanacearum; KEGG, K00122 YP_001944894.1 activates fatty acids by binding to coenzyme A YP_001944895.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001944896.1 COG2941: Ubiquinone biosynthesis protein COQ7, Ralstonia solanacearum; Coq7 protein; KEGG, K06134 YP_001944897.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001944898.1 COG0275: Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis, Ralstonia solanacearum; KEGG, K03438 YP_001944899.1 COG3116: Cell division protein, Ralstonia solanacearum; FtsL protein; KEGG, K03586 YP_001944900.1 COG0768: Cell division protein FtsI/penicillin-binding protein 2, Ralstonia solanacearum; FtsI protein; KEGG, K03587 YP_001944901.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001944902.1 COG0770: UDP-N-acetylmuramyl pentapeptide synthase, Ralstonia solanacearum; KEGG, K01929 YP_001944903.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001944904.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001944905.1 COG0772: Bacterial cell division membrane protein, Ralstonia solanacearum; FtsW protein; KEGG, K03588 YP_001944906.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001944907.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001944908.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001944909.1 COG1589: Cell division septal protein, Ralstonia solanacearum; FtsQ protein; KEGG, K03589 YP_001944910.1 COG0849: Actin-like ATPase involved in cell division, Ralstonia solanacearum; FtsA protein; KEGG, K03590 YP_001944911.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001944912.1 COG0678: Peroxiredoxin, Ralstonia solanacearum YP_001944913.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001944915.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001944916.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001944917.1 COG2607: Predicted ATPase (AAA+ superfamily), Ralstonia solanacearum; KEGG, K06923 YP_001944918.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum; KEGG, K03574 YP_001944920.1 COG4582: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944921.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001944922.1 COG1989: Type II secretory pathway, prepilin signal peptidase PulO and related peptidases, Ralstonia solanacearum; KEGG, K02654 YP_001944923.1 COG1459: Type II secretory pathway, component PulF, Pseudomonas aeruginosa; KEGG, K02653; PilC protein YP_001944924.1 COG2804: Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB, Ralstonia solanacearum; KEGG, K02652; PilB protein YP_001944925.1 COG4536: Putative Mg2+ and Co2+ transporter CorB, Ralstonia solanacearum YP_001944937.1 COG0142: Geranylgeranyl pyrophosphate synthase, Ralstonia solanacearum; KEGG, K00805 YP_001944938.1 COG0261: Ribosomal protein L21, Ralstonia solanacearum; KEGG, K02888 YP_001944939.1 involved in the peptidyltransferase reaction during translation YP_001944940.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001944941.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001944943.1 hydrolyzes diadenosine polyphosphate YP_001944944.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001944945.1 COG2095: Multiple antibiotic transporter, Ralstonia solanacearum YP_001944946.1 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively YP_001944947.1 COG0541: Signal recognition particle GTPase, Ralstonia solanacearum; KEGG, K03106 YP_001944948.1 COG4137: ABC-type uncharacterized transport system, permease component, Ralstonia solanacearum YP_001944949.1 KEGG, K06950 YP_001944950.1 COG3023: Negative regulator of beta-lactamase expression, Ralstonia solanacearum; KEGG, K03806 YP_001944951.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001944952.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001944955.1 COG3133: Outer membrane lipoprotein, Ralstonia solanacearum; KEGG, K06077; SlyB protein YP_001944956.1 COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00856 YP_001944957.1 COG2077: Peroxiredoxin, Ralstonia solanacearum; KEGG, K00435 YP_001944959.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001944960.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001944961.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001944962.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001944963.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum YP_001944965.1 COG0773: UDP-N-acetylmuramate-alanine ligase, Ralstonia solanacearum; KEGG, K02558 YP_001944966.1 COG3150: Predicted esterase, Ralstonia solanacearum; KEGG, K07000 YP_001944967.1 COG0557: Exoribonuclease R, Ralstonia solanacearum; KEGG, K01147 YP_001944968.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001944969.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_001944970.1 COG2939: Carboxypeptidase C (cathepsin A), Ralstonia solanacearum YP_001944972.1 COG1414: Transcriptional regulator, Bacillus halodurans YP_001944973.1 COG3734: 2-keto-3-deoxy-galactonokinase, Sinorhizobium meliloti; KEGG, K00883 YP_001944974.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_001944975.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti; KEGG, K00059 YP_001944976.1 COG1879: ABC-type sugar transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02058 YP_001944977.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001944978.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001944979.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti; KEGG, K00120 YP_001944980.1 COG2017: Galactose mutarotase and related enzymes, Ralstonia solanacearum YP_001944981.1 type 2 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001944983.1 C-terminal domain; COG1546: Uncharacterized protein (competence- and mitomycin-induced), Ralstonia solanacearum; CinA protein; KEGG, K03743 YP_001944984.1 COG1267: Phosphatidylglycerophosphatase A and related proteins, Ralstonia solanacearum; KEGG, K01095 YP_001944985.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_001944986.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001944987.1 COG4290: Guanyl-specific ribonuclease Sa, Ralstonia solanacearum; KEGG, K01167 YP_001944989.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001944990.1 COG2764: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001944991.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001944992.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001944993.1 COG0057: Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase, Pseudomonas aeruginosa; KEGG, K00134 YP_001944994.1 COG1846: Transcriptional regulators, Caulobacter vibrioides YP_001944995.1 COG1024: Enoyl-CoA hydratase/carnithine racemase, Caulobacter vibrioides; KEGG, K01692 YP_001944997.1 COG0477: Permeases of the major facilitator superfamily, Yersinia pestis YP_001944998.1 controls the expression of the cynTSX operon involved in degrading and using cyanate as a sole nitrogen source YP_001944999.1 COG2186: Transcriptional regulators, Ralstonia solanacearum; KEGG, K05799 YP_001945000.1 involved in the transport of C4-dicarboxylates across the membrane YP_001945001.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate YP_001945002.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001945003.1 COG0735: Fe2+/Zn2+ uptake regulation proteins, Ralstonia solanacearum; Fur protein; KEGG, K03711 YP_001945004.1 COG2913: Small protein A (tmRNA-binding), Ralstonia solanacearum; KEGG, K06186 YP_001945005.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001945006.1 COG0811: Biopolymer transport proteins, Ralstonia solanacearum; ExbB protein; KEGG, K03561 YP_001945007.1 COG0848: Biopolymer transport protein, Ralstonia solanacearum; ExbD protein; KEGG, K03559 YP_001945008.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001945009.1 COG2980: Rare lipoprotein B, Ralstonia solanacearum; KEGG, K03643 YP_001945010.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_001945011.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001945012.1 COG1981: Predicted membrane protein, Ralstonia solanacearum; KEGG, K08973 YP_001945013.1 OrfB YP_001945014.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001945015.1 COG0800: 2-keto-3-deoxy-6-phosphogluconate aldolase, Ralstonia solanacearum; KEGG, K01625 YP_001945016.1 COG2610: H+/gluconate symporter and related permeases, Ralstonia solanacearum; KEGG, K03299 YP_001945017.1 COG3265: Gluconate kinase, Ralstonia solanacearum; KEGG, K00851 YP_001945019.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Escherichia coli K12 YP_001945020.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001945021.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945022.1 COG0334: Glutamate dehydrogenase/leucine dehydrogenase, Ralstonia solanacearum; KEGG, K00261 YP_001945023.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Escherichia coli O157:H7; KEGG, K02030 YP_001945024.1 COG0765: ABC-type amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K02029 YP_001945025.1 COG0765: ABC-type amino acid transport system, permease component, Salmonella typhimurium LT2; KEGG, K02029 YP_001945026.1 COG1126: ABC-type polar amino acid transport system, ATPase component, Yersinia pestis; KEGG, K02028 YP_001945027.1 COG3468: Type V secretory pathway, adhesin AidA, Yersinia pestis YP_001945028.1 COG0121: Predicted glutamine amidotransferase, Ralstonia solanacearum; KEGG, K07008 YP_001945029.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001945032.1 COG1765: Predicted redox protein, regulator of disulfide bond formation, Ralstonia solanacearum; KEGG, K07397 YP_001945034.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001945035.1 forms a direct contact with the tRNA during translation YP_001945036.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001945037.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001945038.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001945039.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001945040.1 COG0406: Fructose-2,6-bisphosphatase, Ralstonia solanacearum; KEGG, K01834 YP_001945041.1 COG3662: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945042.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001945043.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001945044.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001945045.1 involved in de novo purine biosynthesis YP_001945046.1 COG2901: Factor for inversion stimulation Fis, transcriptional activator, Ralstonia solanacearum; Fis protein; KEGG, K03557 YP_001945047.1 COG0042: tRNA-dihydrouridine synthase, Ralstonia solanacearum; KEGG, K05540 YP_001945048.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K03185 YP_001945049.1 COG0006: Xaa-Pro aminopeptidase, Ralstonia solanacearum; KEGG, K01262 YP_001945050.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K00799 YP_001945051.1 COG0069: Glutamate synthase domain 2, Ralstonia solanacearum; KEGG, K00264 YP_001945052.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001945053.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum; KEGG, K01554 YP_001945054.1 COG3288: NAD/NADP transhydrogenase alpha subunit, Ralstonia solanacearum; KEGG, K00324 YP_001945055.1 COG3288: NAD/NADP transhydrogenase alpha subunit, Ralstonia solanacearum; KEGG, K00324 YP_001945056.1 COG1282: NAD/NADP transhydrogenase beta subunit, Ralstonia solanacearum; KEGG, K00325 YP_001945057.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945058.1 COG0388: Predicted amidohydrolase, Saccharomyces cerevisiae; KEGG, K01501 YP_001945059.1 COG2378: Predicted transcriptional regulator, Ralstonia solanacearum YP_001945060.1 KEGG, K06996 YP_001945061.1 COG0116: Predicted N6-adenine-specific DNA methylase, Ralstonia solanacearum; KEGG, K07444 YP_001945062.1 COG4389: Site-specific recombinase, Ralstonia solanacearum YP_001945063.1 COG3009: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945064.1 COG3008: Paraquat-inducible protein B, Ralstonia solanacearum; KEGG, K06192 YP_001945065.1 COG2995: Uncharacterized paraquat-inducible protein A, Ralstonia solanacearum; KEGG, K03808 YP_001945066.1 KEGG, K03808 YP_001945067.1 COG3038: Cytochrome B561, Ralstonia solanacearum YP_001945068.1 COG2353: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945069.1 COG2353: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945070.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K03762 YP_001945071.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001945072.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001945073.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_001945074.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001945075.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001945076.1 catalyzes branch migration in Holliday junction intermediates YP_001945077.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; KEGG, K04761 YP_001945078.1 COG0376: Catalase (peroxidase I), Methanosarcina acetivorans str.C2A; KEGG, K03782 YP_001945080.1 COG0783: DNA-binding ferritin-like protein (oxidative damage protectant), Ralstonia solanacearum; KEGG, K04047 YP_001945081.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001945082.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_001945083.1 COG0325: Predicted enzyme with a TIM-barrel fold, Ralstonia solanacearum; KEGG, K06997 YP_001945084.1 COG0247: Fe-S oxidoreductase, Ralstonia solanacearum; KEGG, K00104 YP_001945085.1 COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00104 YP_001945086.1 COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00104 YP_001945087.1 COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00102 YP_001945088.1 COG2096: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00798 YP_001945089.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Sinorhizobium meliloti; KEGG, K05916 YP_001945092.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001945093.1 COG0312: Predicted Zn-dependent proteases and their inactivated homologs, Ralstonia solanacearum; KEGG, K03568 YP_001945094.1 COG0388: Predicted amidohydrolase, Ralstonia solanacearum; KEGG, K01501 YP_001945095.1 COG3164: Predicted membrane protein, Ralstonia solanacearum YP_001945096.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001945097.1 COG0497: ATPase involved in DNA repair, Ralstonia solanacearum; KEGG, K03631; RecN protein YP_001945098.1 catalyzes the phosphorylation of NAD to NADP YP_001945099.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons YP_001945100.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001945101.1 COG1188: Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog), Ralstonia solanacearum; KEGG, K04762 YP_001945103.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001945104.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum YP_001945105.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001945106.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001945107.1 COG0147: Anthranilate/para-aminobenzoate synthases component I, Ralstonia solanacearum; KEGG, K01665 YP_001945108.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001945109.1 COG1428: Deoxynucleoside kinases, Ralstonia solanacearum; KEGG, K00904 YP_001945110.1 COG0801: 7,8-dihydro-6-hydroxymethylpterin- pyrophosphokinase, Ralstonia solanacearum; KEGG, K00950 YP_001945111.1 COG0617: tRNA nucleotidyltransferase/poly(A) polymerase, Ralstonia solanacearum; KEGG, K00970 YP_001945112.1 COG0560: Phosphoserine phosphatase, Ralstonia solanacearum YP_001945113.1 COG0593: ATPase involved in DNA replication initiation, Ralstonia solanacearum; KEGG, K02313 YP_001945114.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001945115.1 COG4319: Ketosteroid isomerase homolog, Ralstonia solanacearum YP_001945116.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001945117.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001945118.1 COG0586: Uncharacterized membrane-associated protein, Ralstonia solanacearum; KEGG, K03975 YP_001945119.1 COG0668: Small-conductance mechanosensitive channel, Nostoc sp. PCC 7120; KEGG, K03442 YP_001945120.1 COG4221: Short-chain alcohol dehydrogenase of unknown specificity, Nostoc sp. PCC 7120 YP_001945122.1 COG3563: Capsule polysaccharide export protein, Neisseria meningitidis Z2491; KEGG, K07266 YP_001945123.1 COG3562: Capsule polysaccharide export protein, Sinorhizobium meliloti; KEGG, K07265 YP_001945125.1 KEGG, K07011 YP_001945127.1 COG3524: Capsule polysaccharide export protein, Campylobacter jejuni; KEGG, K01992 YP_001945128.1 COG1596: Periplasmic protein involved in polysaccharide export, Agrobacterium tumefaciens strain C58; KEGG, K01991 YP_001945129.1 COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component, Campylobacter jejuni; KEGG, K01992 YP_001945130.1 COG1134: ABC-type polysaccharide/polyol phosphate transport system, ATPase component, Campylobacter jejuni; KEGG, K01990 YP_001945131.1 involved in cell wall biogenesis YP_001945136.1 COG0156: 7-keto-8-aminopelargonate synthetase and related enzymes, Sinorhizobium meliloti; KEGG, K00652 YP_001945137.1 COG3321: Polyketide synthase modules and related proteins, Sinorhizobium meliloti YP_001945138.1 COG1091: dTDP-4-dehydrorhamnose reductase, Ralstonia solanacearum; KEGG, K00067 YP_001945139.1 COG1898: dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes, Ralstonia solanacearum; KEGG, K01790 YP_001945140.1 COG1209: dTDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00973 YP_001945141.1 COG1088: dTDP-D-glucose 4,6-dehydratase, Ralstonia solanacearum; KEGG, K01710 YP_001945142.1 COG0121: Predicted glutamine amidotransferase, Sinorhizobium meliloti; KEGG, K07008 YP_001945143.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit, Haemophilus influenzae YP_001945144.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001945147.1 contains two PAAR domains YP_001945148.1 COG1729: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945149.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum; KEGG, K03640 YP_001945150.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001945151.1 COG3064: Membrane protein involved in colicin uptake, Haemophilus influenzae; KEGG, K03646 YP_001945152.1 COG0848: Biopolymer transport protein, Ralstonia solanacearum; KEGG, K03560; TolR protein YP_001945153.1 COG0811: Biopolymer transport proteins, Ralstonia solanacearum; KEGG, K03562; TolQ protein YP_001945154.1 COG0824: Predicted thioesterase, Ralstonia solanacearum; KEGG, K07107 YP_001945155.1 COG4221: Short-chain alcohol dehydrogenase of unknown specificity, Salmonella typhimurium LT2; KEGG, K00540 YP_001945156.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001945157.1 COG1327: Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains, Ralstonia solanacearum; KEGG, K07738 YP_001945158.1 FimT protein; KEGG, K08084 YP_001945160.1 KEGG, K02672; PilW protein YP_001945162.1 KEGG, K02655; PilE protein YP_001945164.1 COG5393: Predicted membrane protein, Ralstonia solanacearum YP_001945165.1 COG4575: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945166.1 COG0450: Peroxiredoxin, Ralstonia solanacearum; KEGG, K00430 YP_001945167.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00252 YP_001945168.1 COG1414: Transcriptional regulator, Ralstonia solanacearum YP_001945169.1 COG3791: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001945171.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K05712 YP_001945173.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08195 YP_001945174.1 An oxygenase that acts to open the ring of homogentisate formingmaleylacetoacetate as part of the catabolism of L-tyrosine and L-phenylalanine YP_001945175.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Ralstonia solanacearum; KEGG, K01555 YP_001945176.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001945177.1 COG2814: Arabinose efflux permease, Mesorhizobium loti; KEGG, K08156 YP_001945178.1 COG0778: Nitroreductase, Ralstonia solanacearum; KEGG, K04719 YP_001945179.1 COG1052: Lactate dehydrogenase and related dehydrogenases, Pseudomonas aeruginosa; KEGG, K03778 YP_001945180.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945181.1 COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase, Vibrio cholerae; KEGG, K00839 YP_001945182.1 COG2207: AraC-type DNA-binding domain-containing proteins, Ralstonia solanacearum YP_001945183.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Pseudomonas aeruginosa YP_001945184.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001945185.1 COG4630: Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A, Ralstonia solanacearum; KEGG, K00087 YP_001945186.1 COG4631: Xanthine dehydrogenase, molybdopterin-binding subunit B, Ralstonia solanacearum; KEGG, K00087 YP_001945188.1 COG4460: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001945189.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945190.1 contains DSBA-like thioredoxin domain YP_001945191.1 COG2358: TRAP-type uncharacterized transport system, periplasmic component, Pseudomonas aeruginosa YP_001945193.1 KEGG, K07518 YP_001945194.1 COG0730: Predicted permeases, Ralstonia solanacearum; KEGG, K07090 YP_001945195.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001945196.1 COG2761: Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis, Xylella fastidiosa 9a5c; involved in polyketide biosynthesis YP_001945197.1 COG2964: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001945198.1 COG2423: Predicted ornithine cyclodeaminase, mu-crystallin homolog, Pseudomonas aeruginosa YP_001945199.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa YP_001945200.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti; KEGG, K00285 YP_001945201.1 COG5295: Autotransporter adhesin, Mesorhizobium loti YP_001945202.1 COG4315: Uncharacterized protein conserved in bacteria, Agrobacterium tumefaciens strain C58 YP_001945203.1 COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog, Ralstonia solanacearum; KEGG, K03088 YP_001945204.1 COG5662: Predicted transmembrane transcriptional regulator (anti-sigma factor), Agrobacterium tumefaciens strain C58 YP_001945208.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001945209.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001945210.1 COG0351: Hydroxymethylpyrimidine/ phosphomethylpyrimidine kinase, Pseudomonas aeruginosa; KEGG, K00941 YP_001945211.1 COG1773: Rubredoxin, Ralstonia solanacearum; RubA protein YP_001945213.1 COG1678: Putative transcriptional regulator, Ralstonia solanacearum; KEGG, K07735 YP_001945214.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001945215.1 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity YP_001945216.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001945217.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_001945218.1 COG0204: 1-acyl-sn-glycerol-3-phosphate acyltransferase, Ralstonia solanacearum; KEGG, K00655 YP_001945219.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001945220.1 COG1682: ABC-type polysaccharide/polyol phosphate export systems, permease component, Pseudomonas aeruginosa; KEGG, K01992 YP_001945221.1 KEGG, K01990 YP_001945223.1 OrfB YP_001945224.1 OrfA YP_001945226.1 COG1216: Predicted glycosyltransferases, Ralstonia solanacearum; KEGG, K07011 YP_001945227.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Vibrio cholerae; KEGG, K01784 YP_001945228.1 COG0472: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase, Pseudomonas aeruginosa YP_001945229.1 COG1086: Predicted nucleoside-diphosphate sugar epimerases, Bacillus halodurans YP_001945230.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001945231.1 COG0472: UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase, Ralstonia solanacearum; KEGG, K02851 YP_001945232.1 COG1087: UDP-glucose 4-epimerase, Ralstonia solanacearum; KEGG, K01784 YP_001945233.1 COG0438: Glycosyltransferase, Sinorhizobium meliloti YP_001945235.1 COG2244: Membrane protein involved in the export of O-antigen and teichoic acid, Ralstonia solanacearum; KEGG, K03328 YP_001945236.1 COG1109: Phosphomannomutase, Ralstonia solanacearum; KEGG, K01840 YP_001945237.1 COG0859: ADP-heptose:LPS heptosyltransferase, Ralstonia solanacearum; KEGG, K02841 YP_001945239.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_001945240.1 COG0378: Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase, Ralstonia solanacearum; KEGG, K03189 YP_001945241.1 COG0830: Urease accessory protein UreF, Ralstonia solanacearum; KEGG, K03188 YP_001945242.1 COG2371: Urease accessory protein UreE, Ralstonia solanacearum; KEGG, K03187 YP_001945243.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits YP_001945244.1 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active YP_001945245.1 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter YP_001945246.1 COG0829: Urease accessory protein UreH, Ralstonia solanacearum; KEGG, K03190 YP_001945247.1 COG0410: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001945248.1 COG4674: Uncharacterized ABC-type transport system, ATPase component, Ralstonia solanacearum; KEGG, K01995 YP_001945249.1 COG4177: ABC-type branched-chain amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K01998 YP_001945250.1 COG0559: Branched-chain amino acid ABC-type transport system, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001945251.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001945252.1 catalyze the conversion of beta amino acids to the corresponding beta keto acid with pyruvate as the amine acceptor YP_001945253.1 COG0607: Rhodanese-related sulfurtransferase, Ralstonia solanacearum; KEGG, K01010 YP_001945254.1 COG2518: Protein-L-isoaspartate carboxylmethyltransferase, Ralstonia solanacearum; KEGG, K00573 YP_001945256.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001945257.1 COG0727: Predicted Fe-S-cluster oxidoreductase, Vibrio cholerae; KEGG, K06940 YP_001945259.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001945260.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001945261.1 COG1961: Site-specific recombinases, DNA invertase Pin homologs, Mesorhizobium loti YP_001945262.1 COG0582: Integrase, Escherichia coli O157:H7 YP_001945264.1 COG2267: Lysophospholipase, Ralstonia solanacearum YP_001945266.1 COG2771: DNA-binding HTH domain-containing proteins, Ralstonia solanacearum; contains extended N-terminus YP_001945267.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001945268.1 COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, Sinorhizobium meliloti; KEGG, K01897 YP_001945269.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K00492 YP_001945272.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001945274.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Mesorhizobium loti; KEGG, K01826 YP_001945275.1 COG2059: Chromate transport protein ChrA, Ralstonia solanacearum YP_001945276.1 COG2059: Chromate transport protein ChrA, Ralstonia solanacearum YP_001945277.1 COG0846: NAD-dependent protein deacetylases, SIR2 family, Aquifex aeolicus YP_001945278.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001945280.1 COG0762: Predicted integral membrane protein, Ralstonia solanacearum; KEGG, K02221 YP_001945281.1 COG5495: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945283.1 KEGG, K06895 YP_001945284.1 COG0043: 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases, Ralstonia solanacearum; KEGG, K03182; UbiD protein YP_001945285.1 COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains), Ralstonia solanacearum YP_001945286.1 COG0436: Aspartate/tyrosine/aromatic aminotransferase, Ralstonia solanacearum; KEGG, K00812 YP_001945287.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001945288.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001945289.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II-like protein; functions in riboflavin synthesis YP_001945290.1 COG3812: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001945291.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001945292.1 COG1985: Pyrimidine reductase, riboflavin biosynthesis, Ralstonia solanacearum; KEGG, K01498 YP_001945293.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001945295.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K07552 YP_001945296.1 glucokinase catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_001945297.1 COG0363: 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase, Ralstonia solanacearum; KEGG, K01057 YP_001945298.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001945299.1 COG1653: ABC-type sugar transport system, periplasmic component, Pseudomonas aeruginosa; KEGG, K02027 YP_001945300.1 COG1175: ABC-type sugar transport systems, permease components, Pseudomonas aeruginosa; KEGG, K02025 YP_001945301.1 COG0395: ABC-type sugar transport system, permease component, Brucella melitensis; KEGG, K02026 YP_001945302.1 COG3839: ABC-type sugar transport systems, ATPase components, Mesorhizobium loti; KEGG, K02023 YP_001945303.1 COG2860: Predicted membrane protein, Ralstonia solanacearum YP_001945304.1 COG2840: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945305.1 COG0492: Thioredoxin reductase, Ralstonia solanacearum; KEGG, K00384 YP_001945306.1 COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins, Ralstonia solanacearum; FtsK/SpoIIIE protein; KEGG, K03466 YP_001945307.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_001945308.1 COG2256: ATPase related to the helicase subunit of the Holliday junction resolvase, Ralstonia solanacearum; KEGG, K07478 YP_001945310.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001945311.1 KEGG, K00496 YP_001945313.1 blocks the formation of polar Z-ring septums YP_001945314.1 COG2894: Septum formation inhibitor-activating ATPase, Ralstonia solanacearum; KEGG, K03609; MinD protein YP_001945315.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_001945318.1 COG0038: Chloride channel protein EriC, Mesorhizobium loti YP_001945319.1 COG0859: ADP-heptose:LPS heptosyltransferase, Ralstonia solanacearum; KEGG, K02841 YP_001945321.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001945322.1 KEGG, K03832; TonB protein YP_001945325.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001945326.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001945327.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001945328.1 COG1561: Uncharacterized stress-induced protein, Ralstonia solanacearum YP_001945329.1 Essential for recycling GMP and indirectly, cGMP YP_001945330.1 Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001945331.1 COG0317: Guanosine polyphosphate pyrophosphohydrolases/synthetases, Ralstonia solanacearum; KEGG, K00951 YP_001945332.1 OrfB YP_001945333.1 OrfA YP_001945334.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001945335.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum; KEGG, K03285 YP_001945337.1 COG1278: Cold shock proteins, Neisseria meningitidis Z2491; KEGG, K03704 YP_001945338.1 COG0847: DNA polymerase III, epsilon subunit and related 3'-5' exonucleases, Neisseria meningitidis Z2491; KEGG, K02342 YP_001945339.1 catalyzes the interconversion of chorismate to prephenate YP_001945342.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Ralstonia solanacearum; KEGG, K02014 YP_001945345.1 COG2261: Predicted membrane protein, Mesorhizobium loti YP_001945346.1 COG0071: Molecular chaperone (small heat shock protein), Sinorhizobium meliloti YP_001945349.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001945350.1 COG0308: Aminopeptidase N, Ralstonia solanacearum; KEGG, K01256 YP_001945352.1 COG2119: Predicted membrane protein, Ralstonia solanacearum YP_001945353.1 Catalyzes the deamination of guanine YP_001945354.1 catalyzes the formation of inosine from adenosine YP_001945355.1 COG1975: Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family, Ralstonia solanacearum; KEGG, K07402 YP_001945356.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001945357.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001945358.1 COG1802: Transcriptional regulators, Caulobacter vibrioides YP_001945359.1 COG2071: Predicted glutamine amidotransferases, Fusobacterium nucleatum; KEGG, K07010 YP_001945360.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001945361.1 COG0457: FOG: TPR repeat, Ralstonia solanacearum YP_001945362.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Bacillus subtilis; KEGG, K03391 YP_001945363.1 KEGG, K00126 YP_001945364.1 COG3383: Uncharacterized anaerobic dehydrogenase, Sinorhizobium meliloti; KEGG, K00123 YP_001945365.1 COG1894: NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit, Sinorhizobium meliloti; KEGG, K05903 YP_001945366.1 COG1905: NADH:ubiquinone oxidoreductase 24 kD subunit, Sinorhizobium meliloti; KEGG, K00127 YP_001945370.1 COG5639: Uncharacterized conserved small protein, Ralstonia solanacearum; conserved among KKS102-type integrative and conjugative element YP_001945371.1 COG2948: Type IV secretory pathway, VirB10 components, Ralstonia solanacearum; KEGG, K03195; TrbI protein YP_001945372.1 COG3504: Type IV secretory pathway, VirB9 components, Ralstonia solanacearum; KEGG, K03204; TrbG protein YP_001945373.1 COG3701: Type IV secretory pathway, TrbF components, Ralstonia solanacearum; KEGG, K03200; TrbF protein YP_001945374.1 type IV secretion VirB6 family YP_001945376.1 COG5314: Conjugal transfer/entry exclusion protein, Ralstonia solanacearum; TrbJ protein YP_001945377.1 type IV secretion system VirB4 family YP_001945378.1 COG5268: Type IV secretory pathway, TrbD component, Ralstonia solanacearum; KEGG, K03198; TrbD protein YP_001945379.1 COG3838: Type IV secretory pathway, VirB2 components (pilins), Ralstonia solanacearum; KEGG, K03197; TrbC protein YP_001945380.1 COG4962: Flp pilus assembly protein, ATPase CpaF, Ralstonia solanacearum; KEGG, K03196; TrbB protein YP_001945382.1 type IV secretion VirD4 coupling protein family YP_001945384.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; TraR protein YP_001945385.1 COG2217: Cation transport ATPase, Mesorhizobium loti; KEGG, K01533 YP_001945387.1 COG2020: Putative protein-S-isoprenylcysteine methyltransferase, Nostoc sp. PCC 7120 YP_001945389.1 COG1276: Putative copper export protein, Ralstonia solanacearum; KEGG, K07245 YP_001945390.1 COG2372: Uncharacterized protein, homolog of Cu resistance protein CopC, Ralstonia solanacearum; KEGG, K07156 YP_001945391.1 COG3667: Uncharacterized protein involved in copper resistance, Ralstonia solanacearum; KEGG, K07233 YP_001945392.1 COG2132: Putative multicopper oxidases, Ralstonia solanacearum YP_001945393.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; CusR protein; KEGG, K07665 YP_001945394.1 COG0642: Signal transduction histidine kinase, Escherichia coli K12; CusS protein; KEGG, K07644 YP_001945395.1 COG3843: Type IV secretory pathway, VirD2 components (relaxase), Ralstonia solanacearum YP_001945396.1 COG4959: Type IV secretory pathway, protease TraF, Ralstonia solanacearum; TraF protein YP_001945399.1 COG1192: ATPases involved in chromosome partitioning, Ralstonia solanacearum; KEGG, K03496; ParA protein YP_001945400.1 COG5534: Plasmid replication initiator protein, Ralstonia solanacearum; conserved among KKS102-type integrative and conjugative element YP_001945402.1 COG5419: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945404.1 COG1396: Predicted transcriptional regulators, Ralstonia solanacearum YP_001945405.1 COG5489: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945408.1 conserved among KKS102-type integrative and conjugative element YP_001945411.1 COG2003: DNA repair proteins, Ralstonia solanacearum; KEGG, K03630; RadC protein YP_001945412.1 COG0640: Predicted transcriptional regulators, Ralstonia solanacearum YP_001945413.1 COG0394: Protein-tyrosine-phosphatase, Mesorhizobium loti YP_001945414.1 COG0798: Arsenite efflux pump ACR3 and related permeases, Agrobacterium tumefaciens strain C58; KEGG, K03325 YP_001945415.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Mesorhizobium loti; KEGG, K00537 YP_001945416.1 COG0431: Predicted flavoprotein, Sinorhizobium meliloti YP_001945420.1 COG3772: Phage-related lysozyme (muraminidase), Ralstonia solanacearum; KEGG, K01185 YP_001945421.1 COG0265: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain, Treponema pallidum; contains C-terminal PDZ domain YP_001945422.1 COG0501: Zn-dependent protease with chaperone function, Ralstonia solanacearum; HtpX protein; KEGG, K03799 YP_001945425.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Mesorhizobium loti; KEGG, K03672 YP_001945427.1 COG3247: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001945431.1 OrfA YP_001945432.1 COG0465: ATP-dependent Zn proteases, Nostoc sp. PCC 7120; FtsH protein; KEGG, K03798 YP_001945433.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Mesorhizobium loti; KEGG, K06131 YP_001945434.1 OrfB YP_001945435.1 OrfA YP_001945436.1 COG0071: Molecular chaperone (small heat shock protein), Thermotoga maritima YP_001945439.1 COG3727: DNA G:T-mismatch repair endonuclease, Caulobacter vibrioides; KEGG, K07458 YP_001945441.1 COG0582: Integrase, Sinorhizobium meliloti YP_001945443.1 COG0582: Integrase, Sinorhizobium meliloti YP_001945445.1 COG0863: DNA modification methylase, Ralstonia solanacearum YP_001945449.1 KEGG, K08364 YP_001945450.1 KEGG, K08363 YP_001945451.1 COG0789: Predicted transcriptional regulators, Sinorhizobium meliloti; KEGG, K08365 YP_001945452.1 COG1742: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945453.1 COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091 YP_001945454.1 Involved in ubiquinone biosynthesis YP_001945455.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum; KEGG, K03286 YP_001945457.1 negatively supercoils closed circular double-stranded DNA YP_001945459.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001945460.1 COG0077: Prephenate dehydratase, Ralstonia solanacearum; KEGG, K04093 YP_001945461.1 COG0287: Prephenate dehydrogenase, Ralstonia solanacearum; KEGG, K00210 YP_001945462.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001945463.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001945464.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001945465.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001945467.1 COG2956: Predicted N-acetylglucosaminyl transferase, Ralstonia solanacearum YP_001945468.1 COG1004: Predicted UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012 YP_001945469.1 COG2870: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase, Ralstonia solanacearum; KEGG, K03272 YP_001945470.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K03274 YP_001945471.1 ComEA protein; KEGG, K02237 YP_001945472.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_001945473.1 COG2951: Membrane-bound lytic murein transglycosylase B, Ralstonia solanacearum; KEGG, K08305 YP_001945474.1 COG0123: Deacetylases, including yeast histone deacetylase and acetoin utilization protein, Ralstonia solanacearum YP_001945475.1 COG2267: Lysophospholipase, Mycobacterium tuberculosis CDC1551; KEGG, K01054 YP_001945476.1 part of the metNIQ transport system for methionine YP_001945477.1 COG2011: ABC-type metal ion transport system, permease component, Ralstonia solanacearum; KEGG, K02072 YP_001945478.1 COG1464: ABC-type metal ion transport system, periplasmic component/surface antigen, Ralstonia solanacearum; KEGG, K02073 YP_001945479.1 COG2086: Electron transfer flavoprotein, beta subunit, Ralstonia solanacearum; KEGG, K03521 YP_001945480.1 COG2025: Electron transfer flavoprotein, alpha subunit, Ralstonia solanacearum; KEGG, K03522 YP_001945481.1 catalyzes the oxidative deamination of D-amino acids YP_001945482.1 COG1522: Transcriptional regulators, Ralstonia solanacearum; KEGG, K03719 YP_001945484.1 COG1533: DNA repair photolyase, Ralstonia solanacearum YP_001945485.1 COG2314: Predicted membrane protein, Ralstonia solanacearum YP_001945486.1 COG2133: Glucose/sorbosone dehydrogenases, Ralstonia solanacearum YP_001945487.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001945488.1 Essential for efficient processing of 16S rRNA YP_001945489.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001945490.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001945491.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum YP_001945492.1 COG1270: Cobalamin biosynthesis protein CobD/CbiB, Ralstonia solanacearum; CobD protein; KEGG, K02227 YP_001945494.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001945495.1 COG0501: Zn-dependent protease with chaperone function, Ralstonia solanacearum; KEGG, K06013 YP_001945496.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001945497.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001945498.1 COG3028: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945499.1 COG0312: Predicted Zn-dependent proteases and their inactivated homologs, Ralstonia solanacearum; KEGG, K03592 YP_001945500.1 COG0262: Dihydrofolate reductase, Ralstonia solanacearum; KEGG, K00287 YP_001945502.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001945503.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001945505.1 COG0640: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001945507.1 COG1607: Acyl-CoA hydrolase, Vibrio cholerae; KEGG, K01073 YP_001945508.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_001945509.1 COG0534: Na+-driven multidrug efflux pump, Brucella melitensis; KEGG, K03327 YP_001945510.1 COG2501: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945514.1 COG1296: Predicted branched-chain amino acid permease (azaleucine resistance), Ralstonia solanacearum YP_001945515.1 COG2207: AraC-type DNA-binding domain-containing proteins, Vibrio cholerae YP_001945516.1 COG3045: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; KEGG, K05805 YP_001945517.1 COG1146: Ferredoxin, Ralstonia solanacearum; KEGG, K05524 YP_001945518.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_001945519.1 COG1556: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00782 YP_001945520.1 COG1055: Na+/H+ antiporter NhaD and related arsenite permeases, Ralstonia solanacearum YP_001945521.1 COG1052: Lactate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00015 YP_001945522.1 COG1322: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; conserved in bacteria YP_001945523.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum YP_001945525.1 COG0303: Molybdopterin biosynthesis enzyme, Ralstonia solanacearum; KEGG, K03750; MoeA protein YP_001945526.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_001945527.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001945528.1 COG1530: Ribonucleases G and E, Ralstonia solanacearum; KEGG, K01128 YP_001945529.1 COG0564: Pseudouridylate synthases, 23S RNA-specific, Ralstonia solanacearum; KEGG, K06179 YP_001945530.1 COG0546: Predicted phosphatases, Ralstonia solanacearum; KEGG, K01091 YP_001945531.1 COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases, Ralstonia solanacearum YP_001945532.1 COG0616: Periplasmic serine proteases (ClpP class), Ralstonia solanacearum; KEGG, K04773 YP_001945533.1 COG0313: Predicted methyltransferases, Ralstonia solanacearum; KEGG, K07056 YP_001945534.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001945535.1 COG1399: Predicted metal-binding, possibly nucleic acid-binding protein, Ralstonia solanacearum; KEGG, K07040 YP_001945536.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001945537.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001945538.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001945539.1 COG0331: (acyl-carrier-protein) S-malonyltransferase, Ralstonia solanacearum; KEGG, K00645 YP_001945540.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001945541.1 carries the fatty acid chain in fatty acid biosynthesis YP_001945542.1 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001945544.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001945545.1 COG3073: Negative regulator of sigma E activity, Ralstonia solanacearum; KEGG, K03597; RseA protein YP_001945546.1 COG3026: Negative regulator of sigma E activity, Ralstonia solanacearum; KEGG, K03598; RseB protein YP_001945547.1 COG0265: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain, Ralstonia solanacearum; KEGG, K01362 YP_001945549.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001945550.1 COG0681: Signal peptidase I, Ralstonia solanacearum; KEGG, K03100 YP_001945551.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001945552.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001945553.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_001945554.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001945555.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001945556.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001945557.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001945558.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001945559.1 COG4394: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945560.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001945561.1 COG0558: Phosphatidylglycerophosphate synthase, Ralstonia solanacearum; KEGG, K00995 YP_001945562.1 COG1247: Sortase and related acyltransferases, Ralstonia solanacearum; KEGG, K03823 YP_001945563.1 COG1396: Predicted transcriptional regulators, Ralstonia solanacearum YP_001945565.1 COG0024: Methionine aminopeptidase, Yersinia pestis; KEGG, K01265 YP_001945566.1 COG1956: GAF domain-containing protein, Xylella fastidiosa 9a5c; KEGG, K07170 YP_001945567.1 COG0583: Transcriptional regulator, Yersinia pestis YP_001945568.1 COG1741: Pirin-related protein, Yersinia pestis; KEGG, K06911 YP_001945569.1 COG2153: Predicted acyltransferase, Pseudomonas aeruginosa; KEGG, K02348 YP_001945570.1 KEGG, K02351 YP_001945572.1 COG1999: Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems, Ralstonia solanacearum; KEGG, K07152; SCO1/SenC/PrrC protein YP_001945573.1 COG1877: Trehalose-6-phosphatase, Salmonella typhimurium LT2; KEGG, K01087 YP_001945574.1 COG0380: Trehalose-6-phosphate synthase, Ralstonia solanacearum; KEGG, K00697 YP_001945575.1 COG1132: ABC-type multidrug transport system, ATPase and permease components, Mesorhizobium loti; KEGG, K06147 YP_001945576.1 COG0438: Glycosyltransferase, Sinorhizobium meliloti YP_001945578.1 KEGG, K08983 YP_001945579.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Ralstonia solanacearum; KEGG, K01706 YP_001945580.1 COG2186: Transcriptional regulators, Ralstonia solanacearum; KEGG, K05799 YP_001945581.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001945582.1 COG3511: Phospholipase C, Ralstonia solanacearum; KEGG, K01114 YP_001945583.1 COG2240: Pyridoxal/pyridoxine/pyridoxamine kinase, Pseudomonas aeruginosa; KEGG, K00868 YP_001945584.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum; KEGG, K01259 YP_001945585.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Yersinia pestis; KEGG, K00494 YP_001945586.1 COG1215: Glycosyltransferases, probably involved in cell wall biogenesis, Synechocystis; KEGG, K00720 YP_001945587.1 COG1032: Fe-S oxidoreductase, Pyrococcus horikoshii; KEGG, K04035 YP_001945588.1 KEGG, K03478 YP_001945591.1 COG4215: ABC-type arginine transport system, permease component, Pseudomonas aeruginosa; KEGG, K02029 YP_001945592.1 COG4160: ABC-type arginine/histidine transport system, permease component, Yersinia pestis; KEGG, K02029 YP_001945593.1 COG4598: ABC-type histidine transport system, ATPase component, Salmonella typhimurium LT2; KEGG, K02028 YP_001945594.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Pseudomonas aeruginosa YP_001945596.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001945597.1 COG3138: Arginine/ornithine N-succinyltransferase beta subunit, Pseudomonas aeruginosa; KEGG, K00673 YP_001945598.1 COG3138: Arginine/ornithine N-succinyltransferase beta subunit, Escherichia coli O157:H7; KEGG, K00673 YP_001945599.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001945600.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001945601.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001945602.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Escherichia coli O157:H7; KEGG, K02030 YP_001945605.1 COG1225: Peroxiredoxin, Caulobacter vibrioides YP_001945606.1 COG0702: Predicted nucleoside-diphosphate-sugar epimerases, Listeria innocua YP_001945608.1 COG0346: Lactoylglutathione lyase and related lyases, Ralstonia solanacearum YP_001945609.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Ralstonia solanacearum; CoxS protein YP_001945610.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; CoxL protein YP_001945611.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001945612.1 COG2207: AraC-type DNA-binding domain-containing proteins, Mesorhizobium loti YP_001945614.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum; KEGG, K07789; MdtC protein YP_001945615.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum; KEGG, K07788; MdtB protein YP_001945616.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum; KEGG, K07799; MdtA protein YP_001945617.1 COG1414: Transcriptional regulator, Pseudomonas aeruginosa YP_001945618.1 KEGG, K07093 YP_001945619.1 COG0004: Ammonia permease, Pseudomonas aeruginosa YP_001945622.1 COG1959: Predicted transcriptional regulator, Ralstonia solanacearum YP_001945623.1 COG2910: Putative NADH-flavin reductase, Ralstonia solanacearum; KEGG, K07118 YP_001945624.1 COG1522: Transcriptional regulators, Caulobacter vibrioides; KEGG, K05800 YP_001945625.1 KEGG, K02010 YP_001945626.1 COG1178: ABC-type Fe3+ transport system, permease component, Agrobacterium tumefaciens strain C58; KEGG, K02011 YP_001945627.1 COG1840: ABC-type Fe3+ transport system, periplasmic component, Brucella melitensis; KEGG, K02012 YP_001945629.1 COG1113: Gamma-aminobutyrate permease and related permeases, Pseudomonas aeruginosa; KEGG, K03293 YP_001945630.1 COG1289: Predicted membrane protein, Ralstonia solanacearum YP_001945631.1 COG1330: Exonuclease V gamma subunit, Salmonella typhimurium LT2; KEGG, K03583 YP_001945632.1 COG1074: ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains), Vibrio cholerae; KEGG, K03582 YP_001945633.1 KEGG, K03581 YP_001945634.1 COG1186: Protein chain release factor B, Pseudomonas aeruginosa YP_001945635.1 COG2200: FOG: EAL domain, Vibrio cholerae YP_001945636.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001945639.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001945640.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Yersinia pestis; contains extended C terminal region YP_001945641.1 COG0477: Permeases of the major facilitator superfamily, Clostridium acetobutylicum YP_001945642.1 COG1409: Predicted phosphohydrolases, Ralstonia solanacearum; KEGG, K03651 YP_001945643.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Ralstonia solanacearum; KEGG, K02052 YP_001945644.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Ralstonia solanacearum; KEGG, K02053 YP_001945645.1 COG0555: ABC-type sulfate transport system, permease component, Ralstonia solanacearum; KEGG, K02053 YP_001945646.1 COG1840: ABC-type Fe3+ transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02055 YP_001945647.1 COG1609: Transcriptional regulators, Ralstonia solanacearum YP_001945650.1 COG2831: Hemolysin activation/secretion protein, Ralstonia solanacearum; KEGG, K07326 YP_001945651.1 COG2267: Lysophospholipase, Ralstonia solanacearum; KEGG, K07024 YP_001945652.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001945653.1 COG0702: Predicted nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum YP_001945654.1 COG1457: Purine-cytosine permease and related proteins, Pseudomonas aeruginosa; KEGG, K03457 YP_001945655.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001945656.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001945657.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001945658.1 AphA protein; COG0123: Deacetylases, including yeast histone deacetylase and acetoin utilization protein, Mesorhizobium loti YP_001945659.1 COG2814: Arabinose efflux permease, Escherichia coli K12; KEGG, K08156 YP_001945661.1 COG0583: Transcriptional regulator, Escherichia coli K12; KEGG, K03717 YP_001945662.1 COG0861: Membrane protein TerC, possibly involved in tellurium resistance, Agrobacterium tumefaciens strain C58 YP_001945666.1 COG1250: 3-hydroxyacyl-CoA dehydrogenase, Archaeoglobus fulgidus; KEGG, K00074 YP_001945667.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001945668.1 MdcL protein YP_001945669.1 MdcM protein YP_001945670.1 MdcA protein YP_001945671.1 acyl carrier protein of malonate decarboxylase YP_001945672.1 The beta subunit catalyzes the decarboxylation of the malonyl moiety on coenzyme A YP_001945673.1 MdcC protein YP_001945674.1 catalyzes the transfer of 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A to the apo-acyl carrier protein of malonate dehydrogenase to form holo-acyl carrier protein YP_001945675.1 COG1767: Triphosphoribosyl-dephospho-CoA synthetase, Pseudomonas aeruginosa; KEGG, K05966 YP_001945676.1 COG0331: (acyl-carrier-protein) S-malonyltransferase, Pseudomonas aeruginosa; KEGG, K00645 YP_001945678.1 COG1926: Predicted phosphoribosyltransferases, Mycobacterium tuberculosis CDC1551; KEGG, K07100 YP_001945679.1 COG4553: Poly-beta-hydroxyalkanoate depolymerase, Ralstonia solanacearum YP_001945681.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; KEGG, K03762 YP_001945682.1 COG1742: Uncharacterized conserved protein, Ralstonia solanacearum YP_001945683.1 3'-5' exonuclease of DNA polymerase III YP_001945684.1 COG0328: Ribonuclease HI, Caulobacter vibrioides; KEGG, K03469 YP_001945685.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum YP_001945686.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Ralstonia solanacearum; KEGG, K01069 YP_001945687.1 COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains), Ralstonia solanacearum; KEGG, K08307 YP_001945688.1 COG0477: Permeases of the major facilitator superfamily, Archaeoglobus fulgidus YP_001945689.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001945690.1 COG1280: Putative threonine efflux protein, Pseudomonas aeruginosa YP_001945691.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001945692.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001945694.1 COG1534: Predicted RNA-binding protein containing KH domain, possibly ribosomal protein, Ralstonia solanacearum; KEGG, K07574 YP_001945695.1 COG0293: 23S rRNA methylase, Ralstonia solanacearum; FtsJ protein; KEGG, K02427 YP_001945696.1 COG0465: ATP-dependent Zn proteases, Ralstonia solanacearum; FtsH protein; KEGG, K03798 YP_001945697.1 COG0294: Dihydropteroate synthase and related enzymes, Ralstonia solanacearum; KEGG, K00796 YP_001945698.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001945699.1 COG0226: ABC-type phosphate transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02040 YP_001945700.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001945701.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_001945702.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001945703.1 COG0704: Phosphate uptake regulator, Ralstonia solanacearum; KEGG, K02039 YP_001945704.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K07657; PhoB protein YP_001945705.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07636; PhoR protein YP_001945706.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001945707.1 COG0248: Exopolyphosphatase, Ralstonia solanacearum; KEGG, K01514 YP_001945710.1 COG0477: Permeases of the major facilitator superfamily, Neisseria meningitidis Z2491; KEGG, K08177 YP_001945714.1 COG0753: Catalase, Mesorhizobium loti; KEGG, K03781 YP_001945719.1 COG2062: Phosphohistidine phosphatase SixA, Ralstonia solanacearum; KEGG, K08296 YP_001945720.1 COG3176: Putative hemolysin, Ralstonia solanacearum YP_001945723.1 COG0534: Na+-driven multidrug efflux pump, Ralstonia solanacearum; KEGG, K03327 YP_001945724.1 COG5626: Uncharacterized conserved small protein, Pseudomonas aeruginosa YP_001945725.1 COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, Mesorhizobium loti; KEGG, K01895 YP_001945726.1 COG0739: Membrane proteins related to metalloendopeptidases, Salmonella typhimurium LT2; KEGG, K06194; NlpD protein YP_001945727.1 COG2017: Galactose mutarotase and related enzymes, Ralstonia solanacearum YP_001945728.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001945733.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001945737.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001945738.1 COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases), Mesorhizobium loti; related to aryl-alcohol dehydrogenases YP_001945740.1 COG1335: Amidases related to nicotinamidase, Salmonella typhimurium LT2 YP_001945741.1 COG0583: Transcriptional regulator, Yersinia pestis YP_001945742.1 EthD protein YP_001945744.1 COG0477: Permeases of the major facilitator superfamily, Bacillus subtilis YP_001945745.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001945746.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001945748.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Caulobacter vibrioides YP_001945749.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001945750.1 COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases, Pseudomonas aeruginosa YP_001945751.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001945752.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Ralstonia solanacearum; KEGG, K07302 YP_001945753.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; CoxL protein YP_001945754.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K00344 YP_001945756.1 COG0845: Membrane-fusion protein, Pseudomonas aeruginosa; KEGG, K02022 YP_001945757.1 COG2274: ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain, Pseudomonas aeruginosa; KEGG, K06148 YP_001945758.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa; KEGG, K03287 YP_001945761.1 COG2124: Cytochrome P450, Bacillus halodurans YP_001945762.1 COG2072: Predicted flavoprotein involved in K+ transport, Caulobacter vibrioides YP_001945763.1 COG1136: ABC-type antimicrobial peptide transport system, ATPase component, Thermotoga maritima; KEGG, K02003 YP_001945764.1 COG4591: ABC-type transport system, involved in lipoprotein release, permease component, Escherichia coli O157:H7; KEGG, K02004; involved in lipoprotein release YP_001945768.1 COG1075: Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold, Xylella fastidiosa 9a5c; KEGG, K01046 YP_001945769.1 acts as a molecular chaperone to fold and export lipase A YP_001945770.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Synechocystis YP_001945771.1 COG2200: FOG: EAL domain, Pseudomonas aeruginosa YP_001945772.1 COG5424: Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C, Pseudomonas aeruginosa YP_001945773.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum YP_001945775.1 COG0741: Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains), Ralstonia solanacearum YP_001945776.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001945777.1 COG1595: DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog, Pseudomonas aeruginosa; KEGG, K03088 YP_001945778.1 COG3712: Fe2+-dicitrate sensor, membrane component, Pseudomonas aeruginosa; KEGG, K07165 YP_001945779.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Pseudomonas aeruginosa; KEGG, K02014 YP_001945781.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Escherichia coli K12; typically associated with flavoprotein oxygenase YP_001945782.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001945783.1 COG2851: H+/citrate symporter, Bacillus subtilis; KEGG, K03300 YP_001945786.1 binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP) YP_001945787.1 catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans YP_001945788.1 COG0457: FOG: TPR repeat, Salmonella typhimurium LT2 YP_001945792.1 COG1215: Glycosyltransferases, probably involved in cell wall biogenesis, Escherichia coli K12; KEGG, K00694 YP_001945795.1 COG1741: Pirin-related protein, Ralstonia solanacearum; KEGG, K06911 YP_001945796.1 COG1765: Predicted redox protein, regulator of disulfide bond formation, Pseudomonas aeruginosa; KEGG, K07397 YP_001945797.1 COG0025: NhaP-type Na+/H+ and K+/H+ antiporters, Agrobacterium tumefaciens strain C58; KEGG, K03316 YP_001945799.1 COG3511: Phospholipase C, Mesorhizobium loti; KEGG, K01114 YP_001945800.1 COG1858: Cytochrome c peroxidase, Ralstonia solanacearum; KEGG, K00428 YP_001945802.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum YP_001945803.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001945804.1 KEGG, K04062; OsmB protein YP_001945805.1 COG3545: Predicted esterase of the alpha/beta hydrolase fold, Ralstonia solanacearum; KEGG, K07002 YP_001945806.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Ralstonia solanacearum; KEGG, K07749 YP_001945807.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001945808.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945809.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001945810.1 COG1051: ADP-ribose pyrophosphatase, Ralstonia solanacearum YP_001945811.1 COG0824: Predicted thioesterase, Pseudomonas aeruginosa; KEGG, K07107 YP_001945812.1 COG0559: Branched-chain amino acid ABC-type transport system, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001945813.1 COG4177: ABC-type branched-chain amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K01998 YP_001945814.1 COG0411: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01995 YP_001945815.1 COG0410: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001945816.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Agrobacterium tumefaciens strain C58; KEGG, K00059 YP_001945818.1 COG3718: Uncharacterized enzyme involved in inositol metabolism, Ralstonia solanacearum; IolB protein; KEGG, K03337 YP_001945819.1 COG1082: Sugar phosphate isomerases/epimerases, Ralstonia solanacearum; IolE protein; KEGG, K03335 YP_001945820.1 COG3962: Acetolactate synthase, Ralstonia solanacearum; IolD protein; KEGG, K03336 YP_001945821.1 COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K03338 YP_001945822.1 COG1879: ABC-type sugar transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02058 YP_001945823.1 COG1129: ABC-type sugar transport system, ATPase component, Ralstonia solanacearum; KEGG, K02056 YP_001945824.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components, Ralstonia solanacearum; KEGG, K02057 YP_001945825.1 COG1082: Sugar phosphate isomerases/epimerases, Ralstonia solanacearum; IolH protein; KEGG, K06605 YP_001945826.1 COG0673: Predicted dehydrogenases and related proteins, Ralstonia solanacearum; KEGG, K00010 YP_001945827.1 COG1082: Sugar phosphate isomerases/epimerases, Ralstonia solanacearum YP_001945828.1 COG0673: Predicted dehydrogenases and related proteins, Ralstonia solanacearum YP_001945829.1 COG1737: Transcriptional regulators, Ralstonia solanacearum YP_001945830.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00140 YP_001945831.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945832.1 COG0425: Predicted redox protein, regulator of disulfide bond formation, Ralstonia solanacearum YP_001945834.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Caulobacter vibrioides YP_001945835.1 COG4254: Uncharacterized protein conserved in bacteria, Caulobacter vibrioides; LysM protein YP_001945836.1 COG4252: Predicted transmembrane sensor domain, Pseudomonas aeruginosa YP_001945838.1 COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963 YP_001945839.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001945840.1 COG0210: Superfamily I DNA and RNA helicases, Ralstonia solanacearum; KEGG, K03657 YP_001945841.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_001945842.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08223 YP_001945843.1 KEGG, K03406 YP_001945844.1 COG1566: Multidrug resistance efflux pump, Pseudomonas aeruginosa YP_001945846.1 COG1289: Predicted membrane protein, Pseudomonas aeruginosa YP_001945847.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001945848.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001945851.1 COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum; KEGG, K00102 YP_001945852.1 COG3308: Predicted membrane protein, Ralstonia solanacearum YP_001945853.1 COG0655: Multimeric flavodoxin WrbA, Ralstonia solanacearum; KEGG, K03809 YP_001945860.1 KEGG, K00558 YP_001945861.1 COG3723: Recombinational DNA repair protein (RecE pathway), Escherichia coli O157:H7; KEGG, K07455; RecT protein YP_001945862.1 KEGG, K01146 YP_001945873.1 COG2932: Predicted transcriptional regulator, Pseudomonas aeruginosa YP_001945879.1 RusA protein YP_001945883.1 COG3728: Phage terminase, small subunit, Mesorhizobium loti; KEGG, K07474 YP_001945884.1 COG1783: Phage terminase large subunit, Haemophilus influenzae YP_001945885.1 COG3567: Uncharacterized protein conserved in bacteria, Xylella fastidiosa 9a5c YP_001945886.1 COG2369: Uncharacterized protein, homolog of phage Mu protein gp30, Xylella fastidiosa 9a5c YP_001945887.1 COG3566: Uncharacterized protein conserved in bacteria, Xylella fastidiosa 9a5c YP_001945907.1 COG3299: Uncharacterized homolog of phage Mu protein gp47, Xylella fastidiosa 9a5c YP_001945909.1 COG1835: Predicted acyltransferases, Agrobacterium tumefaciens strain C58 YP_001945911.1 KEGG, K01185 YP_001945914.1 COG0582: Integrase, Ralstonia solanacearum YP_001945915.1 COG1295: Predicted membrane protein, Ralstonia solanacearum; KEGG, K07058 YP_001945916.1 COG4323: Predicted membrane protein, Ralstonia solanacearum YP_001945917.1 COG0517: FOG: CBS domain, Ralstonia solanacearum; contains CBS domains YP_001945918.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K00655 YP_001945919.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001945920.1 COG0644: Dehydrogenases (flavoproteins), Ralstonia solanacearum; KEGG, K00311 YP_001945921.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00065 YP_001945922.1 COG2771: DNA-binding HTH domain-containing proteins, Ralstonia solanacearum YP_001945923.1 COG1788: Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit, Ralstonia solanacearum; KEGG, K01028 YP_001945924.1 COG2057: Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit, Deinococcus radiodurans; KEGG, K01029 YP_001945925.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum YP_001945926.1 COG0251: Putative translation initiation inhibitor, yjgF family, Pseudomonas aeruginosa YP_001945927.1 COG0317: Guanosine polyphosphate pyrophosphohydrolases/synthetases, Ralstonia solanacearum; KEGG, K00951 YP_001945928.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001945929.1 COG0290: Translation initiation factor 3 (IF-3), Ralstonia solanacearum; KEGG, K02520 YP_001945930.1 COG0291: Ribosomal protein L35, Ralstonia solanacearum; KEGG, K02916 YP_001945931.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001945932.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001945933.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001945934.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001945935.1 COG0789: Predicted transcriptional regulators, Ralstonia solanacearum YP_001945937.1 COG3317: Uncharacterized lipoprotein, Ralstonia solanacearum; KEGG, K07287 YP_001945941.1 COG1434: Uncharacterized conserved protein, Ralstonia solanacearum; conserved in bacteria YP_001945944.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001945945.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001945946.1 COG1386: Predicted transcriptional regulator containing the HTH domain, Ralstonia solanacearum; KEGG, K06024 YP_001945947.1 COG1187: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases, Ralstonia solanacearum; KEGG, K06178 YP_001945948.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001945949.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001945950.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001945951.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001945952.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001945953.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K03446 YP_001945954.1 COG1566: Multidrug resistance efflux pump, Ralstonia solanacearum; KEGG, K03543 YP_001945955.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001945956.1 COG1846: Transcriptional regulators, Ralstonia solanacearum; KEGG, K03712 YP_001945957.1 COG1217: Predicted membrane GTPase involved in stress response, Ralstonia solanacearum; KEGG, K06207 YP_001945958.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001945959.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_001945960.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001945961.1 COG1485: Predicted ATPase, Ralstonia solanacearum; KEGG, K06916 YP_001945962.1 KEGG, K07492 YP_001945963.1 COG4731: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001945964.1 OrfB YP_001945965.1 OrfA YP_001945966.1 COG2831: Hemolysin activation/secretion protein, Ralstonia solanacearum YP_001945970.1 CpaA protein; KEGG, K02278 YP_001945971.1 TadG protein YP_001945972.1 COG3745: Flp pilus assembly protein CpaB, Ralstonia solanacearum; CpaB protein; KEGG, K02279 YP_001945973.1 COG4964: Flp pilus assembly protein, secretin CpaC, Ralstonia solanacearum; CpaC protein; KEGG, K02280 YP_001945974.1 COG4963: Flp pilus assembly protein, ATPase CpaE, Ralstonia solanacearum; CpaE protein; KEGG, K02282 YP_001945975.1 COG4962: Flp pilus assembly protein, ATPase CpaF, Ralstonia solanacearum; CpaF protein; KEGG, K02283 YP_001945976.1 COG4965: Flp pilus assembly protein TadB, Ralstonia solanacearum; TadB protein YP_001945977.1 COG2064: Flp pilus assembly protein TadC, Ralstonia solanacearum; TadC protein YP_001945978.1 COG5010: Flp pilus assembly protein TadD, contains TPR repeats, Ralstonia solanacearum; TadD protein; contains TPR domain YP_001945980.1 COG4655: Predicted membrane protein, Ralstonia solanacearum YP_001945981.1 COG1221: Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain, Ralstonia solanacearum YP_001945983.1 HfqL protein YP_001945985.1 COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, Yersinia pestis; KEGG, K01897 YP_001945986.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001945987.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; KEGG, K08178 YP_001945989.1 COG4318: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001945990.1 COG0659: Sulfate permease and related transporters (MFS superfamily), Ralstonia solanacearum; contains STAS domain YP_001945991.1 COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00847 YP_001945992.1 COG1879: ABC-type sugar transport system, periplasmic component, Mesorhizobium loti; KEGG, K02058 YP_001945993.1 COG4158: Predicted ABC-type sugar transport system, permease component, Mesorhizobium loti; KEGG, K02057 YP_001945994.1 COG1129: ABC-type sugar transport system, ATPase component, Mesorhizobium loti; KEGG, K02056 YP_001945995.1 COG1940: Transcriptional regulator/sugar kinase, Agrobacterium tumefaciens strain C58; KEGG, K00885 YP_001945996.1 COG0655: Multimeric flavodoxin WrbA, Xylella fastidiosa 9a5c; WrbA protein YP_001945997.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001945999.1 COG3025: Uncharacterized conserved protein, Caulobacter vibrioides YP_001946000.1 COG0659: Sulfate permease and related transporters (MFS superfamily), Mycobacterium tuberculosis CDC1551; contains STAS domain YP_001946001.1 COG0628: Predicted permease, Mesorhizobium loti YP_001946002.1 COG2982: Uncharacterized protein involved in outer membrane biogenesis, Ralstonia solanacearum; KEGG, K07290 YP_001946003.1 COG2193: Bacterioferritin (cytochrome b1), Pseudomonas aeruginosa; KEGG, K03594 YP_001946005.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa; KEGG, K00433 YP_001946006.1 COG0789: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001946008.1 COG0789: Predicted transcriptional regulators, Brucella melitensis YP_001946009.1 COG1304: L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases, Mycobacterium leprae; KEGG, K00101 YP_001946010.1 COG0583: Transcriptional regulator, Yersinia pestis YP_001946011.1 COG0477: Permeases of the major facilitator superfamily, Yersinia pestis YP_001946012.1 COG3618: Predicted metal-dependent hydrolase of the TIM-barrel fold, Yersinia pestis; KEGG, K07046 YP_001946013.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Ralstonia solanacearum; KEGG, K07302 YP_001946014.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Ralstonia solanacearum; KEGG, K07303 YP_001946015.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001946016.1 COG2031: Short chain fatty acids transporter, Bacillus halodurans; KEGG, K02106 YP_001946017.1 COG1893: Ketopantoate reductase, Staphylococcus aureus N315; KEGG, K00077 YP_001946018.1 COG3246: Uncharacterized conserved protein, Mesorhizobium loti YP_001946019.1 COG0557: Exoribonuclease R, Ralstonia solanacearum; KEGG, K01147 YP_001946020.1 COG0566: rRNA methylases, Ralstonia solanacearum; KEGG, K03218 YP_001946021.1 COG3023: Negative regulator of beta-lactamase expression, Yersinia pestis; KEGG, K01446 YP_001946022.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001946023.1 COG2186: Transcriptional regulators, Brucella melitensis YP_001946024.1 COG0673: Predicted dehydrogenases and related proteins, Clostridium acetobutylicum; KEGG, K00010 YP_001946025.1 COG0765: ABC-type amino acid transport system, permease component, Pseudomonas aeruginosa; KEGG, K02029 YP_001946026.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001946027.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001946028.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001946029.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001946030.1 COG1051: ADP-ribose pyrophosphatase, Ralstonia solanacearum YP_001946031.1 COG4702: Uncharacterized conserved protein, Sinorhizobium meliloti YP_001946032.1 COG2076: Membrane transporters of cations and cationic drugs, Brucella melitensis; KEGG, K03297 YP_001946033.1 catalyzes the formation of 3-hydroxy-2-methylpropanoate from 3-hydroxy-2-methylpropanoyl-CoA YP_001946034.1 involved in resistance to organic solvents or Fe3+-siderophore transport YP_001946035.1 catalyzes the release of sulfite from alkanesulfonates YP_001946036.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component, Ralstonia solanacearum; KEGG, K02050 YP_001946037.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Ralstonia solanacearum; KEGG, K02049 YP_001946038.1 COG3585: Molybdopterin-binding protein, Ralstonia solanacearum YP_001946041.1 COG0042: tRNA-dihydrouridine synthase, Ralstonia solanacearum; KEGG, K05539 YP_001946047.1 COG2764: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; KEGG, K04750 YP_001946049.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Salmonella typhimurium LT2 YP_001946050.1 COG1733: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001946052.1 COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases), Pseudomonas aeruginosa; related to aryl-alcohol dehydrogenases YP_001946053.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K03762 YP_001946054.1 COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases, Mesorhizobium loti YP_001946055.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946056.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001946057.1 COG0701: Predicted permeases, Escherichia coli O157:H7; KEGG, K07089 YP_001946059.1 COG0842: ABC-type multidrug transport system, permease component, Ralstonia solanacearum; KEGG, K01992 YP_001946060.1 involved in the export of lipooligosaccharides during nodulation YP_001946064.1 Represses a number of genes involved in the response to DNA damage YP_001946065.1 COG1613: ABC-type sulfate transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02048 YP_001946066.1 COG0555: ABC-type sulfate transport system, permease component, Ralstonia solanacearum; KEGG, K02046 YP_001946067.1 COG4208: ABC-type sulfate transport system, permease component, Ralstonia solanacearum; KEGG, K02047 YP_001946068.1 COG1118: ABC-type sulfate/molybdate transport systems, ATPase component, Ralstonia solanacearum; KEGG, K02045 YP_001946069.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; Cbl protein YP_001946070.1 COG1879: ABC-type sugar transport system, periplasmic component, Pseudomonas aeruginosa; KEGG, K02058 YP_001946071.1 COG1129: ABC-type sugar transport system, ATPase component, Pseudomonas aeruginosa YP_001946072.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components, Pseudomonas aeruginosa; KEGG, K02057 YP_001946073.1 COG1609: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K02529 YP_001946074.1 COG0524: Sugar kinases, ribokinase family, Pseudomonas aeruginosa; KEGG, K00852 YP_001946076.1 COG2766: Putative Ser protein kinase, Pseudomonas aeruginosa; KEGG, K07180 YP_001946077.1 COG2718: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001946078.1 COG2719: Uncharacterized conserved protein, Pseudomonas aeruginosa; KEGG, K06415 YP_001946079.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K03761 YP_001946080.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001946081.1 COG0765: ABC-type amino acid transport system, permease component, Yersinia pestis; KEGG, K02029 YP_001946082.1 COG0765: ABC-type amino acid transport system, permease component, Pseudomonas aeruginosa; KEGG, K02029 YP_001946083.1 related to metalloendopeptidases YP_001946084.1 COG1309: Transcriptional regulator, Pseudomonas aeruginosa; KEGG, K03577 YP_001946085.1 MexX; AmrA; involved in resistance to antibiotics; periplasmic membrane fusion protein; functions along with MexY and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery YP_001946086.1 MexY; AmrB; involved in resistance to antibiotics; inner membrane protein; belongs to RND (resistance, nodulation, cell division) family of transporters; functions along with MexX and OprM; part of an inducible system that appears to respond to interference with the cellular translation machinery YP_001946087.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001946088.1 COG3539: P pilus assembly protein, pilin FimA, Escherichia coli K12; KEGG, K07345 YP_001946089.1 COG3188: P pilus assembly protein, porin PapC, Escherichia coli O157:H7; KEGG, K07347 YP_001946090.1 COG3121: P pilus assembly protein, chaperone PapD, Yersinia pestis; KEGG, K07346 YP_001946091.1 KEGG, K07345 YP_001946094.1 RNA polymerase sigma factor involved in the synthesis of the siderophores pyoverdine in Pseudomonas and malleobactin in Burkholderia; also involved in the synthesis of exotoxin and PrpL protease YP_001946095.1 COG3251: Uncharacterized protein conserved in bacteria, Agrobacterium tumefaciens strain C58; KEGG, K05375 YP_001946097.1 COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components, Nostoc sp. PCC 7120; KEGG, K02013 YP_001946098.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_001946100.1 COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component, Nostoc sp. PCC 7120; KEGG, K02016 YP_001946101.1 COG4615: ABC-type siderophore export system, fused ATPase and permease components, Pseudomonas aeruginosa; KEGG, K06160 YP_001946102.1 COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa; KEGG, K03367 YP_001946103.1 COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa YP_001946104.1 COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Sinorhizobium meliloti YP_001946105.1 COG3486: Lysine/ornithine N-monooxygenase, Pseudomonas aeruginosa; KEGG, K03897 YP_001946106.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Ralstonia solanacearum; KEGG, K02014 YP_001946108.1 COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Yersinia pestis; KEGG, K03896 YP_001946109.1 COG4849: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946110.1 COG4861: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946111.1 COG1473: Metal-dependent amidase/aminoacylase/carboxypeptidase, Pseudomonas aeruginosa; KEGG, K01451 YP_001946112.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_001946113.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001946114.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_001946115.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001946116.1 COG3376: High-affinity nickel permease, Ralstonia solanacearum; KEGG, K07241 YP_001946117.1 COG0523: Putative GTPases (G3E family), Pseudomonas aeruginosa; CobW protein; KEGG, K02234 YP_001946118.1 with CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism YP_001946119.1 COG1239: Mg-chelatase subunit ChlI, Pseudomonas aeruginosa; KEGG, K03405 YP_001946120.1 COG1240: Mg-chelatase subunit ChlD, Pseudomonas aeruginosa; KEGG, K03404 YP_001946121.1 COG1671: Uncharacterized protein conserved in bacteria, Yersinia pestis; conserved in bacteria YP_001946122.1 COG3812: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946126.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Pseudomonas aeruginosa; KEGG, K07749 YP_001946127.1 COG2851: H+/citrate symporter, Bacillus subtilis; KEGG, K03300 YP_001946128.1 COG1960: Acyl-CoA dehydrogenases, Caulobacter vibrioides; KEGG, K00249 YP_001946130.1 COG1010: Precorrin-3B methylase, Pseudomonas aeruginosa; KEGG, K00594 YP_001946131.1 catalyzes the formation of precorrin-3 from precorrin-2 YP_001946132.1 catalyzes the interconversion of precorrin-8X and hydrogenobyrinate YP_001946133.1 COG0155: Sulfite reductase, beta subunit (hemoprotein), Pseudomonas aeruginosa; KEGG, K02229 YP_001946134.1 COG2242: Precorrin-6B methylase 2, Pseudomonas aeruginosa; KEGG, K00595 YP_001946135.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_001946136.1 CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6 YP_001946137.1 COG2875: Precorrin-4 methylase, Pseudomonas aeruginosa; KEGG, K00596 YP_001946138.1 COG0625: Glutathione S-transferase, Caulobacter vibrioides; KEGG, K00799 YP_001946139.1 COG4134: ABC-type uncharacterized transport system, periplasmic component, Brucella melitensis; KEGG, K02055 YP_001946140.1 COG3839: ABC-type sugar transport systems, ATPase components, Brucella melitensis; KEGG, K06020 YP_001946141.1 COG1175: ABC-type sugar transport systems, permease components, Brucella melitensis YP_001946142.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Brucella melitensis; KEGG, K02053 YP_001946146.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Ralstonia solanacearum; KEGG, K07749 YP_001946147.1 COG0119: Isopropylmalate/homocitrate/citramalate synthases, Bacillus subtilis; KEGG, K01640 YP_001946148.1 COG0346: Lactoylglutathione lyase and related lyases, Ralstonia solanacearum YP_001946149.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946150.1 COG0477: Permeases of the major facilitator superfamily, Sulfolobus solfataricus YP_001946151.1 COG2070: Dioxygenases related to 2-nitropropane dioxygenase, Pseudomonas aeruginosa; KEGG, K00459 YP_001946152.1 COG3791: Uncharacterized conserved protein, Salmonella typhimurium LT2; GFA protein YP_001946154.1 COG1846: Transcriptional regulators, Sinorhizobium meliloti YP_001946158.1 COG1764: Predicted redox protein, regulator of disulfide bond formation, Sinorhizobium meliloti YP_001946159.1 COG2606: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946160.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001946161.1 COG0598: Mg2+ and Co2+ transporters, Ralstonia solanacearum; KEGG, K03284 YP_001946163.1 COG1748: Saccharopine dehydrogenase and related proteins, Agrobacterium tumefaciens strain C58 YP_001946164.1 COG1522: Transcriptional regulators, Mesorhizobium loti YP_001946168.1 COG4377: Predicted membrane protein, Ralstonia solanacearum YP_001946169.1 COG1609: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K02525 YP_001946170.1 COG1052: Lactate dehydrogenase and related dehydrogenases, Escherichia coli K12; KEGG, K00090 YP_001946171.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001946172.1 COG0524: Sugar kinases, ribokinase family, Pseudomonas aeruginosa; KEGG, K00874 YP_001946174.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946175.1 COG2855: Predicted membrane protein, Yersinia pestis YP_001946176.1 COG0038: Chloride channel protein EriC, Ralstonia solanacearum; KEGG, K03281 YP_001946178.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum YP_001946179.1 COG0841: Cation/multidrug efflux pump, Pseudomonas aeruginosa YP_001946180.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001946182.1 COG3829: Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains, Pseudomonas aeruginosa YP_001946183.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Ralstonia solanacearum; KEGG, K01069 YP_001946184.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Ralstonia solanacearum YP_001946185.1 COG0730: Predicted permeases, Ralstonia solanacearum; KEGG, K07090 YP_001946186.1 COG1177: ABC-type spermidine/putrescine transport system, permease component II, Escherichia coli K12; KEGG, K02053 YP_001946187.1 COG1176: ABC-type spermidine/putrescine transport system, permease component I, Pseudomonas aeruginosa; KEGG, K02054 YP_001946188.1 COG3842: ABC-type spermidine/putrescine transport systems, ATPase components, Neisseria meningitidis MC58; KEGG, K02052 YP_001946189.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Yersinia pestis; KEGG, K02055 YP_001946190.1 COG3313: Predicted Fe-S protein, Ralstonia solanacearum; KEGG, K06938 YP_001946191.1 COG3047: Outer membrane protein W, Ralstonia solanacearum; KEGG, K07275 YP_001946192.1 COG2070: Dioxygenases related to 2-nitropropane dioxygenase, Ralstonia solanacearum; KEGG, K00459 YP_001946193.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00128 YP_001946195.1 COG1522: Transcriptional regulators, Pseudomonas aeruginosa YP_001946196.1 COG1064: Zn-dependent alcohol dehydrogenases, Mesorhizobium loti; KEGG, K00001 YP_001946198.1 COG0488: ATPase components of ABC transporters with duplicated ATPase domains, Ralstonia solanacearum YP_001946199.1 COG2982: Uncharacterized protein involved in outer membrane biogenesis, Ralstonia solanacearum; KEGG, K07290 YP_001946200.1 COG4619: ABC-type uncharacterized transport system, ATPase component, Ralstonia solanacearum; KEGG, K02068 YP_001946201.1 COG0390: ABC-type uncharacterized transport system, permease component, Ralstonia solanacearum; KEGG, K02069 YP_001946204.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Bacillus halodurans; KEGG, K00344 YP_001946205.1 COG0583: Transcriptional regulator, Brucella melitensis YP_001946206.1 COG0560: Phosphoserine phosphatase, Ralstonia solanacearum; KEGG, K01079 YP_001946207.1 catalyzes the formation of L-homocysteine from cystathionine YP_001946209.1 COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00874 YP_001946210.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_001946212.1 COG5394: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; PhaR protein YP_001946213.1 catalyzes the formation of 3-hydroxybutyryl-CoA from acetoacetyl-CoA in polyhydroxyalkanoate synthesis YP_001946214.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001946215.1 COG3243: Poly(3-hydroxyalkanoate) synthetase, Ralstonia solanacearum; KEGG, K03821 YP_001946216.1 COG1496: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K05810 YP_001946217.1 COG0564: Pseudouridylate synthases, 23S RNA-specific, Ralstonia solanacearum; KEGG, K06180 YP_001946218.1 COG4105: DNA uptake lipoprotein, Ralstonia solanacearum; KEGG, K05807 YP_001946219.1 COG1199: Rad3-related DNA helicases, Ralstonia solanacearum; DinG protein; KEGG, K03722 YP_001946222.1 COG2183: Transcriptional accessory protein, Ralstonia solanacearum; KEGG, K06959 YP_001946223.1 COG3158: K+ transporter, Ralstonia solanacearum; KEGG, K03549 YP_001946224.1 COG2236: Predicted phosphoribosyltransferases, Ralstonia solanacearum; KEGG, K07101 YP_001946225.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001946226.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_001946228.1 COG0330: Membrane protease subunits, stomatin/prohibitin homologs, Ralstonia solanacearum; KEGG, K04087 YP_001946229.1 COG0330: Membrane protease subunits, stomatin/prohibitin homologs, Ralstonia solanacearum; KEGG, K04088 YP_001946230.1 COG2262: GTPases, Ralstonia solanacearum; HflX protein; KEGG, K03665 YP_001946231.1 Stimulates the elongation of poly(A) tails YP_001946232.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001946233.1 COG1520: FOG: WD40-like repeat, Ralstonia solanacearum YP_001946234.1 COG2976: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946235.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001946236.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001946237.1 COG1426: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; conserved in bacteria YP_001946238.1 COG0820: Predicted Fe-S-cluster redox enzyme, Ralstonia solanacearum; KEGG, K06941 YP_001946239.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001946240.1 COG0670: Integral membrane protein, interacts with FtsH, Ralstonia solanacearum; KEGG, K06890 YP_001946241.1 OrfA YP_001946242.1 OrfB YP_001946243.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001946244.1 COG3568: Metal-dependent hydrolase, Ralstonia solanacearum; KEGG, K06896 YP_001946245.1 COG3298: Predicted 3'-5' exonuclease related to the exonuclease domain of PolB, Neisseria meningitidis Z2491; KEGG, K07501 YP_001946246.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_001946247.1 COG0739: Membrane proteins related to metalloendopeptidases, Ralstonia solanacearum; KEGG, K06194; NlpD protein YP_001946248.1 COG2518: Protein-L-isoaspartate carboxylmethyltransferase, Ralstonia solanacearum; KEGG, K00573 YP_001946249.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001946250.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Pseudomonas aeruginosa; KEGG, K07749 YP_001946251.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001946252.1 COG0718: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946253.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA YP_001946254.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum; KEGG, K03671 YP_001946255.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001946256.1 COG0789: Predicted transcriptional regulators, Deinococcus radiodurans YP_001946257.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001946258.1 COG3228: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946259.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001946260.1 COG1807: 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family, Ralstonia solanacearum YP_001946261.1 COG0534: Na+-driven multidrug efflux pump, Ralstonia solanacearum; KEGG, K03327 YP_001946262.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001946263.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa; KEGG, K00627 YP_001946264.1 COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit, Pseudomonas aeruginosa; KEGG, K00162 YP_001946265.1 COG1071: Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit, Pseudomonas aeruginosa; KEGG, K00161 YP_001946266.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K03366 YP_001946267.1 COG3199: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001946268.1 COG3284: Transcriptional activator of acetoin/glycerol metabolism, Pseudomonas aeruginosa YP_001946269.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit, Methanothermobacter thermautotrophicus; KEGG, K01607 YP_001946270.1 COG0789: Predicted transcriptional regulators, Clostridium acetobutylicum YP_001946271.1 COG1555: DNA uptake protein and related DNA-binding proteins, Ralstonia solanacearum YP_001946273.1 COG0542: ATPases with chaperone activity, ATP-binding subunit, Ralstonia solanacearum; ClpB protein; KEGG, K03695 YP_001946274.1 COG1959: Predicted transcriptional regulator, Ralstonia solanacearum YP_001946276.1 COG0314: Molybdopterin converting factor, large subunit, Ralstonia solanacearum; KEGG, K03635 YP_001946277.1 COG1977: Molybdopterin converting factor, small subunit, Ralstonia solanacearum; KEGG, K03636 YP_001946278.1 COG0303: Molybdopterin biosynthesis enzyme, Ralstonia solanacearum; KEGG, K03750; MoeA protein YP_001946279.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001946280.1 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine YP_001946281.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001946282.1 COG3737: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09008 YP_001946283.1 COG1807: 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family, Ralstonia solanacearum; KEGG, K07264 YP_001946284.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946285.1 COG0399: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis, Ralstonia solanacearum; KEGG, K07806 YP_001946286.1 COG0463: Glycosyltransferases involved in cell wall biogenesis, Ralstonia solanacearum; KEGG, K00721 YP_001946287.1 COG0223: Methionyl-tRNA formyltransferase, Ralstonia solanacearum; KEGG, K00604 YP_001946288.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K01784 YP_001946289.1 COG0726: Predicted xylanase/chitin deacetylase, Ralstonia solanacearum YP_001946290.1 COG1225: Peroxiredoxin, Ralstonia solanacearum; KEGG, K03564 YP_001946291.1 COG1875: Predicted ATPase related to phosphate starvation-inducible protein PhoH, Ralstonia solanacearum; KEGG, K07175 YP_001946292.1 COG0791: Cell wall-associated hydrolases (invasion-associated proteins), Ralstonia solanacearum YP_001946293.1 COG0306: Phosphate/sulphate permeases, Ralstonia solanacearum; KEGG, K03306 YP_001946294.1 COG1392: Phosphate transport regulator (distant homolog of PhoU), Ralstonia solanacearum; KEGG, K07220 YP_001946295.1 unwinds double stranded DNA YP_001946296.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001946297.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001946298.1 KEGG, K02686 YP_001946299.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001946300.1 COG5662: Predicted transmembrane transcriptional regulator (anti-sigma factor), Ralstonia solanacearum YP_001946301.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001946302.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946303.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_001946304.1 COG3622: Hydroxypyruvate isomerase, Ralstonia solanacearum; KEGG, K01816 YP_001946305.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Mesorhizobium loti; KEGG, K00042 YP_001946306.1 COG1652: Uncharacterized protein containing LysM domain, Ralstonia solanacearum YP_001946307.1 COG0252: L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D, Ralstonia solanacearum; KEGG, K01424 YP_001946310.1 COG2930: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946311.1 COG0438: Glycosyltransferase, Sinorhizobium meliloti YP_001946312.1 COG4637: Predicted ATPase, Pseudomonas aeruginosa YP_001946315.1 COG0666: FOG: Ankyrin repeat, Ralstonia solanacearum; KEGG, K06867 YP_001946316.1 COG0084: Mg-dependent DNase, Ralstonia solanacearum; KEGG, K03424 YP_001946317.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_001946318.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001946319.1 COG1559: Predicted periplasmic solute-binding protein, Ralstonia solanacearum; KEGG, K07082 YP_001946320.1 COG0354: Predicted aminomethyltransferase related to GcvT, Ralstonia solanacearum; KEGG, K06980; related to GcvT YP_001946321.1 COG3332: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001946322.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum YP_001946323.1 COG0657: Esterase/lipase, Ralstonia solanacearum; KEGG, K01066 YP_001946324.1 COG2130: Putative NADP-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K07119 YP_001946325.1 COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism, Ralstonia solanacearum YP_001946328.1 COG2199: FOG: GGDEF domain, Aquifex aeolicus; contains GGDEF domain YP_001946329.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001946330.1 COG1335: Amidases related to nicotinamidase, Ralstonia solanacearum; KEGG, K01440 YP_001946331.1 COG1250: 3-hydroxyacyl-CoA dehydrogenase, Ralstonia solanacearum; KEGG, K01782 YP_001946332.1 activates fatty acids by binding to coenzyme A YP_001946333.1 COG0397: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946334.1 COG0229: Conserved domain frequently associated with peptide methionine sulfoxide reductase, Ralstonia solanacearum; KEGG, K07305 YP_001946335.1 Involved in cell division; probably involved in intracellular septation YP_001946336.1 COG0271: Stress-induced morphogen (activity unknown), Ralstonia solanacearum YP_001946337.1 COG0760: Parvulin-like peptidyl-prolyl isomerase, Ralstonia solanacearum; KEGG, K03769 YP_001946338.1 COG3153: Predicted acetyltransferase, Corynebacterium glutamicum; KEGG, K03824 YP_001946339.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001946340.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Agrobacterium tumefaciens strain C58; KEGG, K00285 YP_001946341.1 COG0063: Predicted sugar kinase, Ralstonia solanacearum YP_001946342.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001946343.1 COG4181: Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component, Ralstonia solanacearum; KEGG, K02003; involved in lysophospholipase L1 biosynthesis YP_001946344.1 COG2755: Lysophospholipase L1 and related esterases, Ralstonia solanacearum; KEGG, K01076 YP_001946345.1 COG0760: Parvulin-like peptidyl-prolyl isomerase, Ralstonia solanacearum; KEGG, K03770 YP_001946346.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K05548 YP_001946347.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001946348.1 COG0466: ATP-dependent Lon protease, bacterial type, Ralstonia solanacearum; KEGG, K01338 YP_001946349.1 binds and unfolds substrates as part of the ClpXP protease YP_001946350.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001946351.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001946352.1 COG1929: Glycerate kinase, Pseudomonas aeruginosa; KEGG, K00865 YP_001946354.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_001946355.1 COG2771: DNA-binding HTH domain-containing proteins, Pseudomonas aeruginosa YP_001946356.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001946358.1 AcuC protein; COG0123: Deacetylases, including yeast histone deacetylase and acetoin utilization protein, Pseudomonas aeruginosa; KEGG, K04768 YP_001946360.1 OrfB YP_001946361.1 OrfA YP_001946362.1 COG1562: Phytoene/squalene synthetase, Ralstonia solanacearum; KEGG, K02291 YP_001946363.1 COG4102: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946364.1 COG5267: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946366.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001946367.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; EnvZ protein; KEGG, K07638 YP_001946368.1 COG0450: Peroxiredoxin, Ralstonia solanacearum; KEGG, K03386 YP_001946369.1 COG2128: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K04756 YP_001946370.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001946371.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001946372.1 COG1197: Transcription-repair coupling factor (superfamily II helicase), Ralstonia solanacearum; KEGG, K03723 YP_001946373.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine YP_001946374.1 COG1171: Threonine dehydratase, Thermotoga maritima; KEGG, K01754 YP_001946378.1 COG5009: Membrane carboxypeptidase/penicillin-binding protein, Ralstonia solanacearum; KEGG, K05366 YP_001946379.1 COG1842: Phage shock protein A (IM30), suppresses sigma54-dependent transcription, Synechocystis; KEGG, K03969 YP_001946380.1 contains FOG: TPR repeat YP_001946381.1 homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001946383.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Pseudomonas aeruginosa; KEGG, K00042 YP_001946384.1 COG3360: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09165 YP_001946385.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946386.1 catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway. YP_001946388.1 COG2351: Transthyretin-like protein, Sinorhizobium meliloti; KEGG, K07127 YP_001946389.1 COG3748: Predicted membrane protein, Ralstonia solanacearum YP_001946390.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_001946391.1 catalyzes the formation of S-ureidoglycolate and urea from allantoate YP_001946392.1 COG3195: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946393.1 COG0726: Predicted xylanase/chitin deacetylase, Ralstonia solanacearum; KEGG, K01463 YP_001946394.1 COG4126: Hydantoin racemase, Sinorhizobium meliloti; HyuE protein; KEGG, K01797 YP_001946395.1 COG1953: Cytosine/uracil/thiamine/allantoin permeases, Yersinia pestis; KEGG, K03457 YP_001946396.1 COG1802: Transcriptional regulators, Ralstonia solanacearum YP_001946397.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_001946398.1 COG0590: Cytosine/adenosine deaminases, Ralstonia solanacearum; KEGG, K01500 YP_001946400.1 COG0477: Permeases of the major facilitator superfamily, Sinorhizobium meliloti YP_001946401.1 COG2188: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K03710 YP_001946402.1 COG1053: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, Pseudomonas aeruginosa; KEGG, K00238 YP_001946403.1 COG1146: Ferredoxin, Pseudomonas aeruginosa YP_001946404.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components, Pseudomonas aeruginosa YP_001946405.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component, Pseudomonas aeruginosa; KEGG, K02050 YP_001946406.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Pseudomonas aeruginosa; KEGG, K02049 YP_001946407.1 COG1413: FOG: HEAT repeat, Pseudomonas aeruginosa; contains FOG: HEAT repeat YP_001946408.1 COG3536: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001946409.1 COG1051: ADP-ribose pyrophosphatase, Caulobacter vibrioides YP_001946410.1 COG1514: 2'-5' RNA ligase, Ralstonia solanacearum; KEGG, K01976 YP_001946411.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Mesorhizobium loti YP_001946412.1 COG1396: Predicted transcriptional regulators, Mesorhizobium loti YP_001946413.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001946415.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001946416.1 COG5486: Predicted metal-binding integral membrane protein, Mesorhizobium loti YP_001946417.1 COG4312: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti YP_001946420.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946421.1 COG2914: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001946422.1 COG2867: Oligoketide cyclase/lipid transport protein, Ralstonia solanacearum YP_001946423.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001946424.1 COG0330: Membrane protease subunits, stomatin/prohibitin homologs, Ralstonia solanacearum YP_001946426.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001946427.1 COG1806: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; conserved in bacteria YP_001946428.1 COG0566: rRNA methylases, Ralstonia solanacearum; KEGG, K03437 YP_001946429.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001946430.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001946431.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001946432.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001946433.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001946434.1 COG2825: Outer membrane protein, Ralstonia solanacearum; KEGG, K06142 YP_001946435.1 COG4775: Outer membrane protein/protective antigen OMA87, Ralstonia solanacearum; KEGG, K07277 YP_001946436.1 COG0750: Predicted membrane-associated Zn-dependent proteases 1, Ralstonia solanacearum; KEGG, K01417 YP_001946437.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001946438.1 COG0575: CDP-diglyceride synthetase, Ralstonia solanacearum; KEGG, K00981 YP_001946439.1 COG0020: Undecaprenyl pyrophosphate synthase, Ralstonia solanacearum; KEGG, K00806 YP_001946440.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001946441.1 Catalyzes the phosphorylation of UMP to UDP YP_001946442.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001946443.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001946444.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001946445.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001946446.1 COG1187: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases, Ralstonia solanacearum; KEGG, K06182 YP_001946447.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001946448.1 COG0272: NAD-dependent DNA ligase (contains BRCT domain type II), Escherichia coli O157:H7; KEGG, K01972 YP_001946450.1 COG1196: Chromosome segregation ATPases, Pseudomonas aeruginosa; KEGG, K03529 YP_001946451.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946452.1 catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate YP_001946453.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001946454.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Ralstonia solanacearum YP_001946455.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001946456.1 involved in methylation of ribosomal protein L3 YP_001946457.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001946458.1 COG0386: Glutathione peroxidase, Ralstonia solanacearum; KEGG, K00432 YP_001946459.1 COG0488: ATPase components of ABC transporters with duplicated ATPase domains, Ralstonia solanacearum; KEGG, K06158 YP_001946461.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001946462.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001946463.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08227 YP_001946464.1 COG0351: Hydroxymethylpyrimidine/ phosphomethylpyrimidine kinase, Escherichia coli O157:H7; KEGG, K00941 YP_001946465.1 COG3782: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001946466.1 COG1573: Uracil-DNA glycosylase, Ralstonia solanacearum; KEGG, K02334 YP_001946467.1 COG0456: Acetyltransferases, Ralstonia solanacearum; KEGG, K03789 YP_001946468.1 COG1214: Inactive homolog of metal-dependent proteases, putative molecular chaperone, Ralstonia solanacearum YP_001946469.1 COG4281: Acyl-CoA-binding protein, Ralstonia solanacearum; KEGG, K08762 YP_001946470.1 COG0513: Superfamily II DNA and RNA helicases, Ralstonia solanacearum; DeaD protein; KEGG, K05592 YP_001946471.1 COG2224: Isocitrate lyase, Ralstonia solanacearum; KEGG, K01637 YP_001946472.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001946473.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946474.1 COG1011: Predicted hydrolase (HAD superfamily), Ralstonia solanacearum; KEGG, K01560 YP_001946475.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001946476.1 COG2105: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946477.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001946478.1 COG2207: AraC-type DNA-binding domain-containing proteins, Ralstonia solanacearum YP_001946480.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001946481.1 COG1752: Predicted esterase of the alpha-beta hydrolase superfamily, Ralstonia solanacearum; KEGG, K07001 YP_001946482.1 COG0791: Cell wall-associated hydrolases (invasion-associated proteins), Ralstonia solanacearum YP_001946483.1 COG4172: ABC-type uncharacterized transport system, duplicated ATPase component, Ralstonia solanacearum; KEGG, K02032 YP_001946484.1 COG4239: ABC-type uncharacterized transport system, permease component, Ralstonia solanacearum; KEGG, K02034 YP_001946485.1 COG4174: ABC-type uncharacterized transport system, permease component, Ralstonia solanacearum; KEGG, K02033 YP_001946486.1 COG4166: ABC-type oligopeptide transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02035 YP_001946488.1 COG3125: Heme/copper-type cytochrome/quinol oxidase, subunit 4, Ralstonia solanacearum; CyoD protein; KEGG, K02300 YP_001946489.1 COG1845: Heme/copper-type cytochrome/quinol oxidase, subunit 3, Pseudomonas aeruginosa; KEGG, K02299 YP_001946490.1 COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1, Ralstonia solanacearum; KEGG, K02298 YP_001946491.1 COG1622: Heme/copper-type cytochrome/quinol oxidases, subunit 2, Ralstonia solanacearum; KEGG, K02297 YP_001946492.1 COG1008: NADH:ubiquinone oxidoreductase subunit 4 (chain M), Ralstonia solanacearum; KEGG, K00342 YP_001946493.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation. YP_001946494.1 COG0037: Predicted ATPase of the PP-loop superfamily implicated in cell cycle control, Ralstonia solanacearum; KEGG, K04075; MesJ protein YP_001946495.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001946496.1 COG0122: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase, Ralstonia solanacearum; KEGG, K01247 YP_001946497.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001946498.1 COG0457: FOG: TPR repeat, Ralstonia solanacearum YP_001946499.1 COG0652: Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family, Ralstonia solanacearum; KEGG, K01802 YP_001946500.1 COG0652: Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family, Ralstonia solanacearum; KEGG, K03768 YP_001946501.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001946502.1 COG1045: Serine acetyltransferase, Ralstonia solanacearum; KEGG, K00640 YP_001946503.1 COG0565: rRNA methylase, Ralstonia solanacearum; KEGG, K02533 YP_001946504.1 COG0483: Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family, Ralstonia solanacearum; KEGG, K01092 YP_001946512.1 This protein performs the mismatch recognition step during the DNA repair process YP_001946514.1 COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2, Ralstonia solanacearum; KEGG, K03775; SlyD protein YP_001946515.1 COG2850: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946518.1 COG1235: Metal-dependent hydrolases of the beta-lactamase superfamily I, Ralstonia solanacearum YP_001946519.1 COG3317: Uncharacterized lipoprotein, Ralstonia solanacearum; KEGG, K07287 YP_001946520.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001946521.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum YP_001946522.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001946523.1 COG1994: Zn-dependent proteases, Ralstonia solanacearum YP_001946524.1 COG0009: Putative translation factor (SUA5), Ralstonia solanacearum; KEGG, K07566 YP_001946525.1 COG0613: Predicted metal-dependent phosphoesterases (PHP family), Ralstonia solanacearum; KEGG, K07053 YP_001946526.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum YP_001946527.1 COG2833: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946528.1 COG0663: Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily, Ralstonia solanacearum YP_001946529.1 COG1281: Disulfide bond chaperones of the HSP33 family, Ralstonia solanacearum; KEGG, K04083 YP_001946531.1 OrfA YP_001946533.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_001946534.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001946535.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001946536.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001946537.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum YP_001946538.1 COG0658: Predicted membrane metal-binding protein, Ralstonia solanacearum; ComEC protein; KEGG, K02238 YP_001946539.1 COG0084: Mg-dependent DNase, Ralstonia solanacearum; KEGG, K03424 YP_001946540.1 COG1136: ABC-type antimicrobial peptide transport system, ATPase component, Ralstonia solanacearum; KEGG, K02003 YP_001946541.1 COG4591: ABC-type transport system, involved in lipoprotein release, permease component, Ralstonia solanacearum; KEGG, K02004 YP_001946542.1 COG4255: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946543.1 COG0608: Single-stranded DNA-specific exonuclease, Ralstonia solanacearum; KEGG, K07462 YP_001946544.1 COG1186: Protein chain release factor B, Ralstonia solanacearum; KEGG, K02836 YP_001946545.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001946548.1 COG0633: Ferredoxin, Ralstonia solanacearum; KEGG, K04755 YP_001946549.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001946550.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001946551.1 COG0316: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946552.1 COG0822: NifU homolog involved in Fe-S cluster formation, Ralstonia solanacearum; KEGG, K04488; NifU protein YP_001946553.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001946554.1 COG1959: Predicted transcriptional regulator, Ralstonia solanacearum YP_001946555.1 COG0394: Protein-tyrosine-phosphatase, Pseudomonas aeruginosa; KEGG, K01104 YP_001946557.1 COG1139: Uncharacterized conserved protein containing a ferredoxin-like domain, Ralstonia solanacearum; contains a ferredoxin-like domain YP_001946558.1 COG0247: Fe-S oxidoreductase, Ralstonia solanacearum; KEGG, K08263 YP_001946559.1 COG1414: Transcriptional regulator, Ralstonia solanacearum YP_001946560.1 COG1686: D-alanyl-D-alanine carboxypeptidase, Ralstonia solanacearum; KEGG, K07262 YP_001946562.1 COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes, Ralstonia solanacearum; KEGG, K00382 YP_001946563.1 COG0508: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes, Ralstonia solanacearum; KEGG, K00627 YP_001946564.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001946565.1 COG2202: FOG: PAS/PAC domain, Ralstonia solanacearum; KEGG, K00936; involved in catabolite control YP_001946566.1 COG4566: Response regulator, Ralstonia solanacearum; involved in catabolite control YP_001946567.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001946568.1 COG0339: Zn-dependent oligopeptidases, Ralstonia solanacearum; KEGG, K01414 YP_001946569.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001946570.1 COG1794: Aspartate racemase, Caulobacter vibrioides; KEGG, K01779 YP_001946571.1 COG0708: Exonuclease III, Ralstonia solanacearum; KEGG, K01142 YP_001946572.1 COG1505: Serine proteases of the peptidase family S9A, Mycobacterium tuberculosis H37Rv; KEGG, K01322 YP_001946573.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum; GlnG protein; KEGG, K07712 YP_001946574.1 COG3852: Signal transduction histidine kinase, nitrogen specific, Ralstonia solanacearum; GlnL protein; KEGG, K07708 YP_001946575.1 COG0174: Glutamine synthetase, Ralstonia solanacearum; KEGG, K01915 YP_001946576.1 COG0607: Rhodanese-related sulfurtransferase, Ralstonia solanacearum YP_001946577.1 COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA, Ralstonia solanacearum YP_001946579.1 COG3000: Sterol desaturase, Ralstonia solanacearum YP_001946580.1 COG3391: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946581.1 COG1643: HrpA-like helicases, Ralstonia solanacearum; HrpA protein; KEGG, K03578 YP_001946582.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001946583.1 COG2924: Fe-S cluster protector protein, Ralstonia solanacearum YP_001946584.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001946585.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Pseudomonas aeruginosa; KEGG, K07749 YP_001946586.1 COG1960: Acyl-CoA dehydrogenases, Pseudomonas aeruginosa YP_001946587.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946588.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Pseudomonas aeruginosa; KEGG, K00833 YP_001946589.1 COG0174: Glutamine synthetase, Caulobacter vibrioides; KEGG, K01915 YP_001946590.1 COG2071: Predicted glutamine amidotransferases, Pseudomonas aeruginosa; KEGG, K07010 YP_001946592.1 COG3741: N-formylglutamate amidohydrolase, Pseudomonas aeruginosa; KEGG, K01458 YP_001946593.1 catalyzes the deimination of N-formimino-L-glutamate to ammonia and N-formyl-L-glutamate YP_001946594.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001946595.1 COG3758: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946596.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001946597.1 COG2188: Transcriptional regulators, Ralstonia solanacearum; KEGG, K05836 YP_001946598.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001946599.1 KEGG, K06133 YP_001946600.1 COG4757: Predicted alpha/beta hydrolase, Ralstonia solanacearum YP_001946601.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001946602.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001946604.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001946605.1 COG2706: 3-carboxymuconate cyclase, Salmonella typhimurium LT2; KEGG, K07404 YP_001946606.1 COG0560: Phosphoserine phosphatase, Caulobacter vibrioides YP_001946607.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Yersinia pestis; KEGG, K02014 YP_001946608.1 COG4147: Predicted symporter, Ralstonia solanacearum YP_001946610.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001946611.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946612.1 COG2862: Predicted membrane protein, Ralstonia solanacearum YP_001946613.1 COG1951: Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain, Ralstonia solanacearum; KEGG, K01676 YP_001946614.1 COG2193: Bacterioferritin (cytochrome b1), Ralstonia solanacearum; KEGG, K03594 YP_001946615.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001946616.1 KEGG, K02192 YP_001946617.1 COG0810: Periplasmic protein TonB, links inner and outer membranes, Ralstonia solanacearum; KEGG, K03832; TonB protein YP_001946618.1 COG0811: Biopolymer transport proteins, Ralstonia solanacearum; ExbB protein; KEGG, K03561 YP_001946619.1 COG0848: Biopolymer transport protein, Ralstonia solanacearum; ExbD protein; KEGG, K03559 YP_001946620.1 COG0583: Transcriptional regulator, Yersinia pestis YP_001946621.1 COG1741: Pirin-related protein, Ralstonia solanacearum; KEGG, K06911 YP_001946624.1 COG0348: Polyferredoxin, Brucella melitensis YP_001946625.1 COG0672: High-affinity Fe2+/Pb2+ permease, Brucella melitensis; KEGG, K07243 YP_001946626.1 involved in iron transport YP_001946627.1 COG3470: Uncharacterized protein probably involved in high-affinity Fe2+ transport, Brucella melitensis; KEGG, K07230; probably involved in high-affinity Fe2+ transport YP_001946628.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001946629.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001946630.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001946631.1 COG0667: Predicted oxidoreductases (related to aryl-alcohol dehydrogenases), Xylella fastidiosa 9a5c; KEGG, K05882 YP_001946632.1 COG2961: Protein involved in catabolism of external DNA, Ralstonia solanacearum; KEGG, K07115 YP_001946635.1 COG0789: Predicted transcriptional regulators, Sinorhizobium meliloti YP_001946640.1 COG2866: Predicted carboxypeptidase, Ralstonia solanacearum YP_001946641.1 COG3022: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946643.1 catalyzes the transfer of an amino moiety YP_001946644.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum YP_001946645.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001946646.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K00799 YP_001946647.1 COG2030: Acyl dehydratase, Ralstonia solanacearum YP_001946648.1 COG2030: Acyl dehydratase, Ralstonia solanacearum YP_001946649.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001946650.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001946651.1 COG5319: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946652.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum; KEGG, K01515 YP_001946654.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946655.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946656.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001946657.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946658.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946659.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946660.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946661.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_001946662.1 COG1894: NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit, Ralstonia solanacearum; KEGG, K00335 YP_001946663.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946664.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946665.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946666.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001946667.1 Catalyzes the transfer of electrons from NADH to quinone YP_001946668.1 COG1314: Preprotein translocase subunit SecG, Ralstonia solanacearum; KEGG, K03075 YP_001946669.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001946670.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K00344 YP_001946671.1 COG1185: Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase), Ralstonia solanacearum; KEGG, K00962 YP_001946672.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001946673.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001946675.1 COG0288: Carbonic anhydrase, Ralstonia solanacearum; KEGG, K01673 YP_001946676.1 COG0659: Sulfate permease and related transporters (MFS superfamily), Ralstonia solanacearum; KEGG, K01672 YP_001946677.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001946678.1 COG1183: Phosphatidylserine synthase, Ralstonia solanacearum; KEGG, K00998 YP_001946679.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001946680.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001946681.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001946682.1 acetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate YP_001946683.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates YP_001946686.1 COG1714: Predicted membrane protein/domain, Ralstonia solanacearum YP_001946687.1 COG2908: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946688.1 COG0438: Glycosyltransferase, Ralstonia solanacearum YP_001946689.1 COG0818: Diacylglycerol kinase, Ralstonia solanacearum; KEGG, K00901 YP_001946690.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001946691.1 COG1611: Predicted Rossmann fold nucleotide-binding protein, Ralstonia solanacearum; KEGG, K06966 YP_001946692.1 Converts glucose to D-glucono-1,5 lactone YP_001946693.1 COG1807: 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family, Ralstonia solanacearum YP_001946694.1 COG3803: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946695.1 COG2872: Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain, Pseudomonas aeruginosa; KEGG, K07050; contains related to alanyl-tRNA synthetase with HxxxH domain YP_001946696.1 COG2346: Truncated hemoglobins, Ralstonia solanacearum; KEGG, K06886 YP_001946697.1 COG3127: Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component, Ralstonia solanacearum; KEGG, K02004; involved in lysophospholipase L1 biosynthesis YP_001946699.1 KEGG, K03297 YP_001946701.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K07667; KdpE protein YP_001946702.1 COG2205: Osmosensitive K+ channel histidine kinase, Ralstonia solanacearum; KEGG, K07646; KdpD protein YP_001946703.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex YP_001946704.1 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001946705.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_001946707.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K00344 YP_001946708.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001946709.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00059 YP_001946710.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001946711.1 COG0217: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946712.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001946713.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001946714.1 catalyzes the formation of deamido-NAD(+) from nicotinate ribonucleotide and ATP YP_001946715.1 COG0799: Uncharacterized homolog of plant Iojap protein, Ralstonia solanacearum YP_001946716.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001946717.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_001946718.1 COG1530: Ribonucleases G and E, Ralstonia solanacearum; KEGG, K08301 YP_001946721.1 COG0477: Permeases of the major facilitator superfamily, Mycobacterium tuberculosis CDC1551 YP_001946723.1 COG5455: Predicted integral membrane protein, Ralstonia solanacearum YP_001946724.1 COG1132: ABC-type multidrug transport system, ATPase and permease components, Ralstonia solanacearum; KEGG, K06147 YP_001946726.1 COG3307: Lipid A core - O-antigen ligase and related enzymes, Ralstonia solanacearum YP_001946727.1 COG0463: Glycosyltransferases involved in cell wall biogenesis, Ralstonia solanacearum; KEGG, K01043; involved in cell wall biogenesis YP_001946728.1 KEGG, K00737 YP_001946729.1 COG0463: Glycosyltransferases involved in cell wall biogenesis, Ralstonia solanacearum; involved in cell wall biogenesis YP_001946730.1 COG0859: ADP-heptose:LPS heptosyltransferase, Yersinia pestis; KEGG, K02849 YP_001946731.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001946732.1 COG1054: Predicted sulfurtransferase, Ralstonia solanacearum; KEGG, K07146 YP_001946733.1 this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu YP_001946734.1 COG0513: Superfamily II DNA and RNA helicases, Ralstonia solanacearum; DeaD protein; KEGG, K05592 YP_001946737.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001946739.1 COG1674: DNA segregation ATPase FtsK/SpoIIIE and related proteins, Ralstonia solanacearum; FtsK/SpoIIIE protein; KEGG, K03466 YP_001946740.1 COG2706: 3-carboxymuconate cyclase, Pseudomonas aeruginosa YP_001946741.1 COG3387: Glucoamylase and related glycosyl hydrolases, Ralstonia solanacearum YP_001946742.1 COG4553: Poly-beta-hydroxyalkanoate depolymerase, Ralstonia solanacearum YP_001946743.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001946744.1 Involved in the electron transport chain YP_001946745.1 COG0177: Predicted EndoIII-related endonuclease, Ralstonia solanacearum; KEGG, K07457 YP_001946746.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946748.1 COG2863: Cytochrome c553, Ralstonia solanacearum YP_001946749.1 COG2863: Cytochrome c553, Ralstonia solanacearum YP_001946750.1 COG0714: MoxR-like ATPases, Ralstonia solanacearum YP_001946751.1 COG3825: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946752.1 COG3135: Uncharacterized protein involved in benzoate metabolism, Pseudomonas aeruginosa; KEGG, K05782 YP_001946753.1 COG0176: Transaldolase, Ralstonia solanacearum; KEGG, K00616 YP_001946754.1 COG2764: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; KEGG, K04750 YP_001946755.1 COG0591: Na+/proline symporter, Sulfolobus solfataricus; KEGG, K03307 YP_001946757.1 COG0421: Spermidine synthase, Ralstonia solanacearum; SpeE2 protein YP_001946759.1 COG4679: Phage-related protein, Xylella fastidiosa 9a5c YP_001946760.1 uncharacterized conserved small protein YP_001946761.1 COG3663: G:T/U mismatch-specific DNA glycosylase, Caulobacter vibrioides; KEGG, K01249 YP_001946762.1 KEGG, K03181 YP_001946763.1 molecular chaperone YP_001946764.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum YP_001946766.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001946767.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00837 YP_001946768.1 COG0251: Putative translation initiation inhibitor, yjgF family, Ralstonia solanacearum YP_001946769.1 COG0384: Predicted epimerase, PhzC/PhzF homolog, Agrobacterium tumefaciens strain C58; KEGG, K06998 YP_001946771.1 COG2059: Chromate transport protein ChrA, Bacillus halodurans YP_001946772.1 COG4125: Predicted membrane protein, Ralstonia solanacearum YP_001946773.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946774.1 COG5615: Predicted integral membrane protein, Pseudomonas aeruginosa YP_001946775.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001946776.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001946777.1 COG0488: ATPase components of ABC transporters with duplicated ATPase domains, Ralstonia solanacearum; KEGG, K06020 YP_001946779.1 RubA protein YP_001946781.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Bacillus halodurans; KEGG, K00034 YP_001946782.1 COG2312: Erythromycin esterase homolog, Sinorhizobium meliloti; KEGG, K00573 YP_001946783.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti YP_001946784.1 COG1309: Transcriptional regulator, Mesorhizobium loti YP_001946785.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001946789.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli K12; KEGG, K08169 YP_001946790.1 COG3911: Predicted ATPase, Mesorhizobium loti YP_001946791.1 COG0380: Trehalose-6-phosphate synthase, Ralstonia solanacearum; KEGG, K00697 YP_001946795.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component, Xylella fastidiosa 9a5c; KEGG, K02049 YP_001946796.1 COG4986: ABC-type anion transport system, duplicated permease component, Xylella fastidiosa 9a5c; KEGG, K02050 YP_001946798.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K02484 YP_001946799.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K02483 YP_001946801.1 COG1741: Pirin-related protein, Ralstonia solanacearum; KEGG, K06911 YP_001946802.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Salmonella typhimurium LT2; KEGG, K02030 YP_001946803.1 COG4215: ABC-type arginine transport system, permease component, Pseudomonas aeruginosa; KEGG, K02029 YP_001946804.1 COG4160: ABC-type arginine/histidine transport system, permease component, Yersinia pestis; KEGG, K02029 YP_001946805.1 COG4598: ABC-type histidine transport system, ATPase component, Pseudomonas aeruginosa; KEGG, K02028 YP_001946806.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Sinorhizobium meliloti; KEGG, K00657 YP_001946807.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946808.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001946809.1 COG0347: Nitrogen regulatory protein PII, Ralstonia solanacearum; KEGG, K04751 YP_001946810.1 NH(3)-dependent; catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001946811.1 COG3146: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946812.1 KEGG, K07461 YP_001946813.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001946814.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00128 YP_001946815.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001946816.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001946817.1 COG3071: Uncharacterized enzyme of heme biosynthesis, Ralstonia solanacearum; KEGG, K02498 YP_001946818.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane and the formation of precorrin-2 from uroporphyrin III and S-adenosyl-L-methionine by two sequential methylation reactions; functions in tetrapyrrole and heme biosynthesis YP_001946819.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001946820.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001946821.1 COG0500: SAM-dependent methyltransferases, Escherichia coli O157:H7 YP_001946822.1 COG1396: Predicted transcriptional regulators, Mesorhizobium loti YP_001946823.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001946824.1 COG0637: Predicted phosphatase/phosphohexomutase, Vibrio cholerae; KEGG, K01091 YP_001946826.1 COG1982: Arginine/lysine/ornithine decarboxylases, Ralstonia solanacearum; KEGG, K01582 YP_001946827.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001946828.1 KEGG, K04565 YP_001946829.1 COG0489: ATPases involved in chromosome partitioning, Ralstonia solanacearum; KEGG, K03593 YP_001946830.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum YP_001946831.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001946832.1 COG2911: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946833.1 COG0729: Outer membrane protein, Ralstonia solanacearum; KEGG, K07278 YP_001946835.1 COG1354: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K05896 YP_001946836.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001946837.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001946838.1 COG1192: ATPases involved in chromosome partitioning, Ralstonia solanacearum YP_001946840.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001946841.1 COG2087: Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase, Ralstonia solanacearum; KEGG, K02231 YP_001946842.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001946843.1 cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase YP_001946844.1 COG0614: ABC-type Fe3+-hydroxamate transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02016 YP_001946845.1 COG0406: Fructose-2,6-bisphosphatase, Ralstonia solanacearum YP_001946846.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_001946847.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001946848.1 COG1120: ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components, Ralstonia solanacearum; KEGG, K02013 YP_001946849.1 COG0609: ABC-type Fe3+-siderophore transport system, permease component, Ralstonia solanacearum; KEGG, K02015 YP_001946852.1 COG2947: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946853.1 COG3471: Predicted periplasmic/secreted protein, Ralstonia solanacearum YP_001946854.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001946855.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; IlvR protein; LysR family transcriptional regulator YP_001946856.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001946859.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_001946860.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001946861.1 COG0795: Predicted permeases, Ralstonia solanacearum; KEGG, K07091 YP_001946862.1 COG0795: Predicted permeases, Ralstonia solanacearum; KEGG, K07091 YP_001946863.1 COG2138: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K03795 YP_001946864.1 catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1 YP_001946865.1 COG2895: GTPases - Sulfate adenylate transferase subunit 1, Ralstonia solanacearum; KEGG, K00956 YP_001946866.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001946867.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001946868.1 COG3749: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001946869.1 COG0155: Sulfite reductase, beta subunit (hemoprotein), Ralstonia solanacearum; KEGG, K00381 YP_001946870.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001946871.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001946872.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti; KEGG, K00059 YP_001946873.1 COG0596: Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa YP_001946874.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946875.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946876.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa YP_001946878.1 COG2372: Uncharacterized protein, homolog of Cu resistance protein CopC, Salmonella typhimurium LT2; KEGG, K07156 YP_001946879.1 COG1187: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases, Ralstonia solanacearum; KEGG, K06183 YP_001946881.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum YP_001946882.1 catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose YP_001946883.1 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001946884.1 COG0456: Acetyltransferases, Yersinia pestis YP_001946886.1 COG0410: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001946887.1 COG0411: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01995 YP_001946888.1 COG4177: ABC-type branched-chain amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K01998 YP_001946889.1 COG0559: Branched-chain amino acid ABC-type transport system, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001946891.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001946892.1 COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2, Ralstonia solanacearum; KEGG, K03774; SlpA protein YP_001946893.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001946894.1 required for 70S ribosome assembly YP_001946895.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001946896.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001946897.1 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide YP_001946898.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001946899.1 COG1398: Fatty-acid desaturase, Ralstonia solanacearum; KEGG, K00507 YP_001946900.1 COG3264: Small-conductance mechanosensitive channel, Ralstonia solanacearum YP_001946901.1 COG0144: tRNA and rRNA cytosine-C5-methylases, Ralstonia solanacearum; KEGG, K03500 YP_001946902.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001946903.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_001946904.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001946905.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001946906.1 catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, which is then decarboxylated to form 4'-phosphopantotheine YP_001946907.1 catalyzes the formation of dUMP from dUTP YP_001946908.1 COG4705: Uncharacterized membrane-anchored protein conserved in bacteria, Ralstonia solanacearum YP_001946909.1 COG1113: Gamma-aminobutyrate permease and related permeases, Pseudomonas aeruginosa YP_001946910.1 COG0542: ATPases with chaperone activity, ATP-binding subunit, Ralstonia solanacearum; ClpA protein; KEGG, K03694 YP_001946911.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001946912.1 COG1278: Cold shock proteins, Ralstonia solanacearum; KEGG, K03704 YP_001946914.1 COG2132: Putative multicopper oxidases, Pasteurella multocida; KEGG, K08100 YP_001946916.1 COG2838: Monomeric isocitrate dehydrogenase, Xylella fastidiosa 9a5c; KEGG, K00031 YP_001946917.1 Converts isocitrate to alpha ketoglutarate YP_001946918.1 COG1187: 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases, Neisseria meningitidis MC58; KEGG, K06181 YP_001946920.1 COG1430: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09005 YP_001946921.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001946922.1 COG3376: High-affinity nickel permease, Salmonella typhimurium LT2; KEGG, K07241 YP_001946923.1 COG0656: Aldo/keto reductases, related to diketogulonate reductase, Mesorhizobium loti; KEGG, K05885 YP_001946924.1 COG2188: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K03710 YP_001946925.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Ralstonia solanacearum; KEGG, K01796 YP_001946926.1 COG0372: Citrate synthase, Agrobacterium tumefaciens strain C58 YP_001946928.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001946929.1 COG2200: FOG: EAL domain, Clostridium acetobutylicum YP_001946930.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum YP_001946931.1 COG4539: Predicted membrane protein, Pseudomonas aeruginosa YP_001946932.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Pseudomonas aeruginosa YP_001946933.1 COG2059: Chromate transport protein ChrA, Pseudomonas aeruginosa; KEGG, K07240 YP_001946934.1 COG0605: Superoxide dismutase, Ralstonia solanacearum; KEGG, K00518 YP_001946935.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001946936.1 Transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001946937.1 COG2835: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K00912 YP_001946938.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001946939.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001946940.1 COG2912: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946941.1 COG0728: Uncharacterized membrane protein, putative virulence factor, Ralstonia solanacearum; KEGG, K03980 YP_001946942.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001946944.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001946945.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001946946.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001946947.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001946948.1 COG2606: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K03976 YP_001946949.1 COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, Mesorhizobium loti; KEGG, K01911 YP_001946950.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_001946951.1 COG0350: Methylated DNA-protein cysteine methyltransferase, Ralstonia solanacearum; KEGG, K00567 YP_001946952.1 COG1600: Uncharacterized Fe-S protein, Ralstonia solanacearum YP_001946953.1 COG0802: Predicted ATPase or kinase, Ralstonia solanacearum; KEGG, K06925 YP_001946954.1 COG0860: N-acetylmuramoyl-L-alanine amidase, Ralstonia solanacearum; KEGG, K01448 YP_001946955.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum; KEGG, K03298 YP_001946956.1 COG1741: Pirin-related protein, Ralstonia solanacearum; KEGG, K06911 YP_001946957.1 COG3118: Thioredoxin domain-containing protein, Ralstonia solanacearum; KEGG, K05838 YP_001946958.1 COG1179: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1, Ralstonia solanacearum YP_001946959.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_001946960.1 COG2230: Cyclopropane fatty acid synthase and related methyltransferases, Ralstonia solanacearum; KEGG, K00574 YP_001946961.1 COG1801: Uncharacterized conserved protein, Ralstonia solanacearum YP_001946962.1 COG0225: Peptide methionine sulfoxide reductase, Ralstonia solanacearum; KEGG, K07304 YP_001946965.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Ralstonia solanacearum; KEGG, K00492 YP_001946966.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001946967.1 COG1878: Predicted metal-dependent hydrolase, Ralstonia solanacearum; KEGG, K01432 YP_001946968.1 COG3844: Kynureninase, Ralstonia solanacearum; KEGG, K01556 YP_001946969.1 COG3483: Tryptophan 2,3-dioxygenase (vermilion), Ralstonia solanacearum; KEGG, K00453 YP_001946970.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001946971.1 COG1893: Ketopantoate reductase, Salmonella typhimurium LT2; KEGG, K00077 YP_001946972.1 COG1012: NAD-dependent aldehyde dehydrogenases, Mesorhizobium loti; KEGG, K00141 YP_001946973.1 catalyzes the formation of benzaldehyde from benzoylformate YP_001946974.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946975.1 COG0246: Mannitol-1-phosphate/altronate dehydrogenases, Ralstonia solanacearum; KEGG, K00045 YP_001946976.1 COG1070: Sugar (pentulose and hexulose) kinases, Ralstonia solanacearum; KEGG, K00854 YP_001946977.1 COG2390: Transcriptional regulator, contains sigma factor-related N-terminal domain, Ralstonia solanacearum YP_001946978.1 COG2814: Arabinose efflux permease, Pseudomonas aeruginosa YP_001946979.1 COG1680: Beta-lactamase class C and other penicillin binding proteins, Pseudomonas aeruginosa YP_001946980.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001946981.1 COG3839: ABC-type sugar transport systems, ATPase components, Ralstonia solanacearum; KEGG, K02023 YP_001946982.1 COG0637: Predicted phosphatase/phosphohexomutase, Ralstonia solanacearum YP_001946983.1 COG0395: ABC-type sugar transport system, permease component, Ralstonia solanacearum; KEGG, K02026 YP_001946984.1 COG1175: ABC-type sugar transport systems, permease components, Ralstonia solanacearum; KEGG, K02025 YP_001946985.1 COG1653: ABC-type sugar transport system, periplasmic component, Ralstonia solanacearum; KEGG, K02027 YP_001946986.1 COG4573: Predicted tagatose 6-phosphate kinase, Ralstonia solanacearum; KEGG, K00917 YP_001946987.1 COG0524: Sugar kinases, ribokinase family, Ralstonia solanacearum; KEGG, K00847 YP_001946988.1 Converts D-sorbitol to L-sorbose YP_001946989.1 COG0735: Fe2+/Zn2+ uptake regulation proteins, Pseudomonas aeruginosa YP_001946990.1 COG0803: ABC-type metal ion transport system, periplasmic component/surface adhesin, Mycobacterium leprae; KEGG, K02077 YP_001946991.1 COG1121: ABC-type Mn/Zn transport systems, ATPase component, Mycobacterium leprae; KEGG, K02074 YP_001946992.1 COG1108: ABC-type Mn2+/Zn2+ transport systems, permease components, Mycobacterium leprae; KEGG, K02075 YP_001946993.1 COG0627: Predicted esterase, Ralstonia solanacearum; KEGG, K03929 YP_001946994.1 COG1062: Zn-dependent alcohol dehydrogenases, class III, Ralstonia solanacearum; KEGG, K00121 YP_001946995.1 COG1070: Sugar (pentulose and hexulose) kinases, Sinorhizobium meliloti; KEGG, K00854 YP_001946996.1 COG2233: Xanthine/uracil permeases, Ralstonia solanacearum; KEGG, K03458 YP_001946997.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001946998.1 COG0841: Cation/multidrug efflux pump, Salmonella typhimurium LT2; KEGG, K03296 YP_001946999.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum; KEGG, K03585 YP_001947000.1 COG1309: Transcriptional regulator, Ralstonia solanacearum; KEGG, K03577 YP_001947001.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Pseudomonas aeruginosa YP_001947005.1 COG0265: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain, Ralstonia solanacearum; KEGG, K01362 YP_001947006.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07645 YP_001947007.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K02483 YP_001947008.1 COG2027: D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4), Ralstonia solanacearum; KEGG, K07259 YP_001947009.1 COG3000: Sterol desaturase, Mesorhizobium loti YP_001947010.1 COG3240: Phospholipase/lecithinase/hemolysin, Ralstonia solanacearum YP_001947011.1 COG0009: Putative translation factor (SUA5), Ralstonia solanacearum; KEGG, K07566 YP_001947012.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_001947013.1 COG0041: Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase, Ralstonia solanacearum; KEGG, K01588 YP_001947014.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001947015.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001947016.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001947017.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001947018.1 COG4392: Predicted membrane protein, Ralstonia solanacearum YP_001947019.1 COG1296: Predicted branched-chain amino acid permease (azaleucine resistance), Ralstonia solanacearum YP_001947020.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001947022.1 COG0859: ADP-heptose:LPS heptosyltransferase, Ralstonia solanacearum; KEGG, K02843 YP_001947024.1 COG0429: Predicted hydrolase of the alpha/beta-hydrolase fold, Ralstonia solanacearum; KEGG, K07019 YP_001947026.1 COG4783: Putative Zn-dependent protease, contains TPR repeats, Ralstonia solanacearum; contains TPR repeats YP_001947027.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001947028.1 KEGG, K03832; TonB protein YP_001947029.1 COG3307: Lipid A core - O-antigen ligase and related enzymes, Ralstonia solanacearum YP_001947030.1 COG4969: Tfp pilus assembly protein, major pilin PilA, Ralstonia solanacearum; KEGG, K02650; PilA protein YP_001947031.1 COG0861: Membrane protein TerC, possibly involved in tellurium resistance, Pseudomonas aeruginosa YP_001947032.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_001947033.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001947035.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001947036.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001947037.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K02483 YP_001947038.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07649 YP_001947039.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947040.1 COG0582: Integrase, Sinorhizobium meliloti YP_001947046.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947047.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Pseudomonas aeruginosa YP_001947048.1 COG0693: Putative intracellular protease/amidase, Nostoc sp. PCC 7120 YP_001947049.1 COG0662: Mannose-6-phosphate isomerase, Neisseria meningitidis Z2491 YP_001947050.1 COG0744: Membrane carboxypeptidase (penicillin-binding protein), Ralstonia solanacearum YP_001947051.1 COG3791: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947052.1 COG0477: Permeases of the major facilitator superfamily, Corynebacterium glutamicum YP_001947053.1 COG3813: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti YP_001947054.1 COG2186: Transcriptional regulators, Mesorhizobium loti YP_001947055.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Sinorhizobium meliloti; KEGG, K01684 YP_001947056.1 KEGG, K07245 YP_001947057.1 COG2863: Cytochrome c553, Pseudomonas aeruginosa YP_001947058.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa YP_001947059.1 COG0513: Superfamily II DNA and RNA helicases, Ralstonia solanacearum; DeaD protein; KEGG, K05592 YP_001947062.1 COG0405: Gamma-glutamyltransferase, Ralstonia solanacearum; KEGG, K00681 YP_001947063.1 COG1349: Transcriptional regulators of sugar metabolism, Ralstonia solanacearum; KEGG, K02444 YP_001947066.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_001947067.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_001947068.1 COG0580: Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family), Thermotoga maritima; KEGG, K02440 YP_001947069.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Mesorhizobium loti; KEGG, K00529 YP_001947070.1 COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases, Mesorhizobium loti; KEGG, K05710 YP_001947071.1 COG3239: Fatty acid desaturase, Mesorhizobium loti YP_001947072.1 COG1879: ABC-type sugar transport system, periplasmic component, Sinorhizobium meliloti YP_001947074.1 COG4130: Predicted sugar epimerase, Ralstonia solanacearum; IolI protein; KEGG, K06606 YP_001947075.1 COG0673: Predicted dehydrogenases and related proteins, Caulobacter vibrioides; KEGG, K00010 YP_001947076.1 COG0637: Predicted phosphatase/phosphohexomutase, Pseudomonas aeruginosa YP_001947077.1 COG0108: 3,4-dihydroxy-2-butanone 4-phosphate synthase, Ralstonia solanacearum; KEGG, K02858 YP_001947079.1 COG1396: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001947080.1 COG2814: Arabinose efflux permease, Pseudomonas aeruginosa; KEGG, K08156 YP_001947081.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947082.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001947083.1 COG1702: Phosphate starvation-inducible protein PhoH, predicted ATPase, Ralstonia solanacearum; KEGG, K06217; PhoH protein YP_001947084.1 contains unknown N-terminal domain/putative metalloprotease C-terminal domain YP_001947085.1 COG3703: Uncharacterized protein involved in cation transport, Ralstonia solanacearum; ChaC protein; KEGG, K07232 YP_001947086.1 COG4535: Putative Mg2+ and Co2+ transporter CorC, Ralstonia solanacearum; KEGG, K06189 YP_001947087.1 Transfers the fatty acyl group on membrane lipoproteins YP_001947088.1 COG0457: FOG: TPR repeat, Ralstonia solanacearum YP_001947089.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001947090.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001947091.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001947092.1 COG0204: 1-acyl-sn-glycerol-3-phosphate acyltransferase, Ralstonia solanacearum; KEGG, K00655 YP_001947093.1 COG1451: Predicted metal-dependent hydrolase, Ralstonia solanacearum; KEGG, K07043 YP_001947094.1 COG0346: Lactoylglutathione lyase and related lyases, Neisseria meningitidis Z2491; KEGG, K01759 YP_001947095.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001947096.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001947097.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001947098.1 COG0760: Parvulin-like peptidyl-prolyl isomerase, Ralstonia solanacearum; KEGG, K03771; SurA protein YP_001947099.1 COG1452: Organic solvent tolerance protein OstA, Ralstonia solanacearum; KEGG, K04744 YP_001947100.1 COG3178: Predicted phosphotransferase related to Ser/Thr protein kinases, Ralstonia solanacearum; KEGG, K07102 YP_001947101.1 KEGG, K00966 YP_001947102.1 COG5265: ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components, Ralstonia solanacearum; KEGG, K06147 YP_001947103.1 COG1607: Acyl-CoA hydrolase, Ralstonia solanacearum; KEGG, K01076 YP_001947105.1 COG1526: Uncharacterized protein required for formate dehydrogenase activity, Ralstonia solanacearum; KEGG, K02379 YP_001947106.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001947107.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation YP_001947108.1 COG1250: 3-hydroxyacyl-CoA dehydrogenase, Ralstonia solanacearum; KEGG, K00022 YP_001947109.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001947110.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001947111.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Salmonella typhimurium LT2; KEGG, K06132 YP_001947112.1 converts dATP to dAMP and pyrophosphate YP_001947113.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001947114.1 COG2928: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947115.1 COG2331: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; conserved in bacteria YP_001947116.1 COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum YP_001947117.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_001947118.1 COG3165: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; KEGG, K03690 YP_001947119.1 COG4395: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947120.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_001947121.1 COG3536: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947122.1 COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases, Ralstonia solanacearum YP_001947123.1 COG0277: FAD/FMN-containing dehydrogenases, Ralstonia solanacearum YP_001947125.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001947126.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001947127.1 COG0251: Putative translation initiation inhibitor, yjgF family, Ralstonia solanacearum; KEGG, K07567 YP_001947128.1 COG3653: N-acyl-D-aspartate/D-glutamate deacylase, Ralstonia solanacearum; KEGG, K06015 YP_001947129.1 COG1737: Transcriptional regulators, Ralstonia solanacearum YP_001947130.1 COG3616: Predicted amino acid aldolase or racemase, Ralstonia solanacearum; KEGG, K01753 YP_001947131.1 COG0693: Putative intracellular protease/amidase, Brucella melitensis; KEGG, K05520 YP_001947132.1 COG1846: Transcriptional regulators, Ralstonia solanacearum YP_001947133.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947135.1 COG0657: Esterase/lipase, Ralstonia solanacearum YP_001947138.1 COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases, Caulobacter vibrioides YP_001947139.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Pseudomonas aeruginosa YP_001947140.1 COG0501: Zn-dependent protease with chaperone function, Yersinia pestis; KEGG, K07387 YP_001947142.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00023 YP_001947143.1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis YP_001947145.1 COG1192: ATPases involved in chromosome partitioning, Pseudomonas aeruginosa; KEGG, K03496 YP_001947146.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA YP_001947147.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947148.1 COG0178: Excinuclease ATPase subunit, Ralstonia solanacearum; KEGG, K03701 YP_001947149.1 COG0628: Predicted permease, Ralstonia solanacearum YP_001947150.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001947151.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Ralstonia solanacearum YP_001947152.1 COG1280: Putative threonine efflux protein, Ralstonia solanacearum YP_001947153.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001947154.1 COG0475: Kef-type K+ transport systems, membrane components, Ralstonia solanacearum; KEGG, K03455 YP_001947155.1 COG0794: Predicted sugar phosphate isomerase involved in capsule formation, Ralstonia solanacearum; KEGG, K06041 YP_001947156.1 COG1778: Low specificity phosphatase (HAD superfamily), Ralstonia solanacearum; KEGG, K03270 YP_001947157.1 COG3117: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947158.1 COG1934: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; conserved in bacteria YP_001947159.1 COG1137: ABC-type (unclassified) transport system, ATPase component, Ralstonia solanacearum; KEGG, K06861 YP_001947160.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001947161.1 COG1544: Ribosome-associated protein Y (PSrp-1), Ralstonia solanacearum; KEGG, K05808 YP_001947162.1 COG1762: Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type), Ralstonia solanacearum; KEGG, K02806 YP_001947163.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_001947164.1 COG1660: Predicted P-loop-containing kinase, Ralstonia solanacearum; KEGG, K06958 YP_001947165.1 COG2802: Uncharacterized protein, similar to the N-terminal domain of Lon protease, Ralstonia solanacearum; KEGG, K07157 YP_001947166.1 COG1194: A/G-specific DNA glycosylase, Ralstonia solanacearum; KEGG, K03575 YP_001947167.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001947168.1 COG0457: FOG: TPR repeat, Ralstonia solanacearum YP_001947169.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_001947170.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001947171.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001947172.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001947173.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001947174.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001947175.1 COG1145: Ferredoxin, Ralstonia solanacearum YP_001947176.1 KEGG, K01178 YP_001947182.1 contains CheY-like receiver domain YP_001947184.1 COG0582: Integrase, Ralstonia solanacearum YP_001947185.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001947186.1 COG0742: N6-adenine-specific methylase, Ralstonia solanacearum; KEGG, K00599 YP_001947187.1 COG0552: Signal recognition particle GTPase, Ralstonia solanacearum; KEGG, K03110 YP_001947188.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K01800 YP_001947189.1 COG0547: Anthranilate phosphoribosyltransferase, Ralstonia solanacearum; KEGG, K00766 YP_001947190.1 COG0119: Isopropylmalate/homocitrate/citramalate synthases, Ralstonia solanacearum; KEGG, K01649 YP_001947193.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001947195.1 COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Escherichia coli O157:H7; KEGG, K00425 YP_001947196.1 COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Agrobacterium tumefaciens strain C58; KEGG, K00426 YP_001947197.1 YbgT protein YP_001947198.1 COG1263: Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific, Pseudomonas aeruginosa; KEGG, K02803 YP_001947199.1 COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria), Pseudomonas aeruginosa; KEGG, K02766 YP_001947200.1 COG2222: Predicted phosphosugar isomerases, Pseudomonas aeruginosa; KEGG, K01504 YP_001947201.1 COG1820: N-acetylglucosamine-6-phosphate deacetylase, Pseudomonas aeruginosa; KEGG, K01443 YP_001947202.1 COG2188: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K03710 YP_001947203.1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis. It is not the major replicative DNA polymerase. YP_001947204.1 COG0389: Nucleotidyltransferase/DNA polymerase involved in DNA repair, Ralstonia solanacearum; involved in DNA repair YP_001947206.1 COG1101: ABC-type uncharacterized transport system, ATPase component, Ralstonia solanacearum; KEGG, K05833 YP_001947207.1 COG4120: ABC-type uncharacterized transport system, permease component, Ralstonia solanacearum; KEGG, K05832 YP_001947208.1 COG2984: ABC-type uncharacterized transport system, periplasmic component, Ralstonia solanacearum; KEGG, K01989 YP_001947210.1 KEGG, K02073 YP_001947211.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03406 YP_001947213.1 COG1999: Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems, Ralstonia solanacearum; KEGG, K07152; SCO1/SenC/PrrC protein YP_001947214.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001947215.1 COG1612: Uncharacterized protein required for cytochrome oxidase assembly, Ralstonia solanacearum; KEGG, K02259 YP_001947217.1 COG3346: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947218.1 COG1845: Heme/copper-type cytochrome/quinol oxidase, subunit 3, Ralstonia solanacearum; KEGG, K02276 YP_001947220.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001947222.1 COG0843: Heme/copper-type cytochrome/quinol oxidases, subunit 1, Ralstonia solanacearum; KEGG, K02274 YP_001947223.1 COG1622: Heme/copper-type cytochrome/quinol oxidases, subunit 2, Ralstonia solanacearum; KEGG, K02275 YP_001947224.1 COG5488: Integral membrane protein, Ralstonia solanacearum YP_001947225.1 BioC protein; COG0500: SAM-dependent methyltransferases, Ralstonia solanacearum; KEGG, K02169 YP_001947226.1 COG1040: Predicted amidophosphoribosyltransferases, Ralstonia solanacearum YP_001947227.1 COG0219: Predicted rRNA methylase (SpoU class), Ralstonia solanacearum; KEGG, K03216 YP_001947228.1 COG2110: Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1, Pseudomonas aeruginosa; KEGG, K00985 YP_001947229.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001947230.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001947231.1 COG0695: Glutaredoxin and related proteins, Ralstonia solanacearum; KEGG, K03676 YP_001947232.1 COG0607: Rhodanese-related sulfurtransferase, Ralstonia solanacearum; KEGG, K01010 YP_001947233.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001947234.1 COG0793: Periplasmic protease, Ralstonia solanacearum; KEGG, K03797 YP_001947235.1 COG0476: Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2, Ralstonia solanacearum; KEGG, K03751; MoeB protein YP_001947236.1 COG1080: Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria), Ralstonia solanacearum; KEGG, K02766 YP_001947237.1 COG1925: Phosphotransferase system, HPr-related proteins, Ralstonia solanacearum; KEGG, K02784 YP_001947238.1 COG2893: Phosphotransferase system, mannose/fructose-specific component IIA, Ralstonia solanacearum; KEGG, K02821 YP_001947239.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001947240.1 KEGG, K01919 YP_001947241.1 COG0004: Ammonia permease, Pseudomonas aeruginosa; KEGG, K03320 YP_001947242.1 COG0347: Nitrogen regulatory protein PII, Ralstonia solanacearum; KEGG, K04752 YP_001947243.1 COG2960: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947244.1 COG0606: Predicted ATPase with chaperone activity, Ralstonia solanacearum; KEGG, K07391 YP_001947246.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum YP_001947247.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum; KEGG, K02481 YP_001947248.1 COG4191: Signal transduction histidine kinase regulating C4-dicarboxylate transport system, Ralstonia solanacearum; DctB protein YP_001947249.1 involved in the transport of C4-dicarboxylates across the membrane YP_001947250.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_001947252.1 COG1804: Predicted acyl-CoA transferases/carnitine dehydratase, Pseudomonas aeruginosa; KEGG, K07749 YP_001947253.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001947254.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001947255.1 COG1250: 3-hydroxyacyl-CoA dehydrogenase, Ralstonia solanacearum; KEGG, K01782 YP_001947256.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947257.1 COG0405: Gamma-glutamyltransferase, Ralstonia solanacearum; KEGG, K00681 YP_001947258.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transport system, permease component, Sinorhizobium meliloti; KEGG, K02050 YP_001947259.1 COG4525: ABC-type taurine transport system, ATPase component, Sinorhizobium meliloti; KEGG, K02049 YP_001947260.1 COG4521: ABC-type taurine transport system, periplasmic component, Mesorhizobium loti; KEGG, K02051 YP_001947262.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001947263.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001947265.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001947266.1 COG2921: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09158 YP_001947267.1 COG0115: Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase, Bacillus subtilis; KEGG, K00824 YP_001947268.1 COG1686: D-alanyl-D-alanine carboxypeptidase, Ralstonia solanacearum; KEGG, K07258 YP_001947269.1 COG2945: Predicted hydrolase of the alpha/beta superfamily, Ralstonia solanacearum; KEGG, K07018 YP_001947270.1 COG3411: Ferredoxin, Ralstonia solanacearum YP_001947271.1 COG5652: Predicted integral membrane protein, Ralstonia solanacearum YP_001947273.1 COG1463: ABC-type transport system involved in resistance to organic solvents, periplasmic component, Ralstonia solanacearum; KEGG, K02067 YP_001947274.1 COG1127: ABC-type transport system involved in resistance to organic solvents, ATPase component, Ralstonia solanacearum; KEGG, K02065 YP_001947275.1 COG0767: ABC-type transport system involved in resistance to organic solvents, permease component, Ralstonia solanacearum; KEGG, K02066 YP_001947276.1 COG0737: 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases, Ralstonia solanacearum; KEGG, K01119 YP_001947277.1 COG0790: FOG: TPR repeat, SEL1 subfamily, Ralstonia solanacearum YP_001947278.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001947279.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001947281.1 COG2870: ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase, Ralstonia solanacearum; KEGG, K00992 YP_001947283.1 COG1752: Predicted esterase of the alpha-beta hydrolase superfamily, Ralstonia solanacearum; KEGG, K07001 YP_001947285.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001947286.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Ralstonia solanacearum YP_001947287.1 COG1414: Transcriptional regulator, Ralstonia solanacearum YP_001947290.1 COG0646: Methionine synthase I (cobalamin-dependent), methyltransferase domain, Ralstonia solanacearum; KEGG, K00548 YP_001947291.1 COG1410: Methionine synthase I, cobalamin-binding domain, Ralstonia solanacearum; KEGG, K00548 YP_001947293.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001947294.1 COG3087: Cell division protein, Ralstonia solanacearum YP_001947295.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Ralstonia solanacearum; DsbA protein; KEGG, K03673 YP_001947296.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00540 YP_001947297.1 COG0747: ABC-type dipeptide transport system, periplasmic component, Pseudomonas aeruginosa; KEGG, K02035 YP_001947298.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Ralstonia solanacearum YP_001947299.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_001947300.1 COG0288: Carbonic anhydrase, Ralstonia solanacearum; KEGG, K01673 YP_001947301.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00079 YP_001947302.1 COG3012: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947303.1 COG0412: Dienelactone hydrolase and related enzymes, Ralstonia solanacearum YP_001947304.1 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate YP_001947305.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_001947306.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001947307.1 COG0502: Biotin synthase and related enzymes, Ralstonia solanacearum; KEGG, K01012 YP_001947308.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947309.1 COG1540: Uncharacterized proteins, homologs of lactam utilization protein B, Pseudomonas aeruginosa; KEGG, K07160 YP_001947311.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism YP_001947312.1 COG2049: Allophanate hydrolase subunit 1, Pseudomonas aeruginosa YP_001947313.1 COG1984: Allophanate hydrolase subunit 2, Pseudomonas aeruginosa; KEGG, K06350 YP_001947316.1 COG3142: Uncharacterized protein involved in copper resistance, Listeria innocua; KEGG, K06201 YP_001947317.1 COG2200: FOG: EAL domain, Mesorhizobium loti YP_001947318.1 COG0025: NhaP-type Na+/H+ and K+/H+ antiporters, Yersinia pestis; KEGG, K03316 YP_001947319.1 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001947322.1 COG3209: Rhs family protein, Pseudomonas aeruginosa YP_001947323.1 COG3501: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947324.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001947327.1 COG2969: Stringent starvation protein B, Ralstonia solanacearum; KEGG, K03600 YP_001947328.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K03599 YP_001947329.1 COG2857: Cytochrome c1, Ralstonia solanacearum; KEGG, K00413 YP_001947330.1 COG1290: Cytochrome b subunit of the bc complex, Ralstonia solanacearum; KEGG, K00412 YP_001947331.1 COG0723: Rieske Fe-S protein, Ralstonia solanacearum; KEGG, K00411 YP_001947332.1 COG0327: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947333.1 COG0265: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain, Ralstonia solanacearum; KEGG, K01362 YP_001947334.1 COG0805: Sec-independent protein secretion pathway component TatC, Ralstonia solanacearum; KEGG, K03118; TatC protein YP_001947335.1 COG1826: Sec-independent protein secretion pathway components, Ralstonia solanacearum; KEGG, K03117; TatB protein YP_001947336.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_001947337.1 COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases, Neisseria meningitidis Z2491; KEGG, K02503; involved in cell-cycle regulation YP_001947338.1 COG3671: Predicted membrane protein, Ralstonia solanacearum YP_001947339.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis YP_001947340.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001947341.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001947342.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001947343.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001947344.1 COG2095: Multiple antibiotic transporter, Ralstonia solanacearum; KEGG, K05595 YP_001947345.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001947346.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001947347.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001947348.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_001947349.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001947350.1 COG5007: Predicted transcriptional regulator, BolA superfamily, Ralstonia solanacearum YP_001947351.1 COG0842: ABC-type multidrug transport system, permease component, Ralstonia solanacearum; KEGG, K01992 YP_001947352.1 COG1131: ABC-type multidrug transport system, ATPase component, Ralstonia solanacearum; KEGG, K01990 YP_001947353.1 KEGG, K07122 YP_001947354.1 COG2854: ABC-type transport system involved in resistance to organic solvents, auxiliary component, Ralstonia solanacearum; KEGG, K07323; involved in resistance to organic solvents YP_001947355.1 COG2853: Surface lipoprotein, Ralstonia solanacearum; KEGG, K04754 YP_001947356.1 COG1463: ABC-type transport system involved in resistance to organic solvents, periplasmic component, Ralstonia solanacearum; KEGG, K02067 YP_001947357.1 COG0767: ABC-type transport system involved in resistance to organic solvents, permease component, Ralstonia solanacearum; KEGG, K02066 YP_001947358.1 COG1127: ABC-type transport system involved in resistance to organic solvents, ATPase component, Ralstonia solanacearum; KEGG, K02065 YP_001947359.1 COG0352: Thiamine monophosphate synthase, Ralstonia solanacearum; KEGG, K00788 YP_001947360.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001947361.1 with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate YP_001947362.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Ralstonia solanacearum; KEGG, K03153; ThiO protein YP_001947363.1 COG4178: ABC-type uncharacterized transport system, permease and ATPase components, Ralstonia solanacearum; KEGG, K02471 YP_001947364.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti YP_001947365.1 COG0477: Permeases of the major facilitator superfamily, Yersinia pestis YP_001947366.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Agrobacterium tumefaciens strain C58; KEGG, K00285 YP_001947367.1 KEGG, K01975 YP_001947368.1 COG1115: Na+/alanine symporter, Vibrio cholerae; KEGG, K03310 YP_001947369.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001947370.1 COG0069: Glutamate synthase domain 2, Ralstonia solanacearum; KEGG, K00284 YP_001947371.1 COG1943: Transposase and inactivated derivatives, Ralstonia solanacearum; KEGG, K07491 YP_001947372.1 COG3047: Outer membrane protein W, Ralstonia solanacearum; KEGG, K07275 YP_001947373.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_001947374.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_001947375.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_001947376.1 COG1175: ABC-type sugar transport systems, permease components, Yersinia pestis; KEGG, K05814 YP_001947377.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_001947378.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001947379.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001947380.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001947381.1 KEGG, K02666; PilQ protein YP_001947385.1 COG5009: Membrane carboxypeptidase/penicillin-binding protein, Ralstonia solanacearum; KEGG, K05366 YP_001947386.1 OrfA YP_001947387.1 OrfB YP_001947388.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_001947390.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001947391.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001947392.1 COG0755: ABC-type transport system involved in cytochrome c biogenesis, permease component, Ralstonia solanacearum YP_001947393.1 COG1333: ResB protein required for cytochrome c biosynthesis, Ralstonia solanacearum; KEGG, K07399 YP_001947394.1 COG2863: Cytochrome c553, Ralstonia solanacearum YP_001947395.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001947396.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001947397.1 COG4232: Thiol:disulfide interchange protein, Ralstonia solanacearum; DsbD protein; KEGG, K04084 YP_001947398.1 KEGG, K03926 YP_001947399.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001947400.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001947401.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001947402.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001947403.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001947404.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001947405.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001947406.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001947407.1 late assembly protein YP_001947408.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001947409.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001947410.1 binds 5S rRNA along with protein L5 and L25 YP_001947411.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001947412.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001947413.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001947414.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001947415.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001947416.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001947417.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001947418.1 one of the stabilizing components for the large ribosomal subunit YP_001947419.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001947420.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001947421.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001947422.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001947423.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001947424.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001947425.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001947426.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001947427.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001947428.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001947429.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001947430.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001947431.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001947432.1 COG0514: Superfamily II DNA helicase, Ralstonia solanacearum; KEGG, K03654; RecQ protein YP_001947433.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001947434.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001947435.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001947436.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001947437.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001947438.1 binds directly to 23S ribosomal RNA YP_001947439.1 Modulates Rho-dependent transcription termination YP_001947440.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001947441.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001947442.1 COG2755: Lysophospholipase L1 and related esterases, Pseudomonas aeruginosa YP_001947443.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA YP_001947444.1 with PaaBCDE catalyzes the hydroxylation of phenylacetyl-CoA; involved in phenylacetate degradation YP_001947445.1 COG3396: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K02611 YP_001947446.1 COG2151: Predicted metal-sulfur cluster biosynthetic enzyme, Ralstonia solanacearum; KEGG, K02612 YP_001947447.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Ralstonia solanacearum; KEGG, K02613 YP_001947449.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001947450.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum YP_001947451.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001947452.1 COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins, Ralstonia solanacearum; KEGG, K00457 YP_001947454.1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates YP_001947455.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_001947456.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001947457.1 COG1881: Phospholipid-binding protein, Salmonella typhimurium LT2; KEGG, K06910 YP_001947458.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001947461.1 COG3047: Outer membrane protein W, Ralstonia solanacearum; KEGG, K07275 YP_001947462.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001947463.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001947464.1 COG1280: Putative threonine efflux protein, Sinorhizobium meliloti; KEGG, K05834 YP_001947465.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Pseudomonas aeruginosa; KEGG, K00020 YP_001947466.1 COG1656: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09122 YP_001947468.1 COG0845: Membrane-fusion protein, Mesorhizobium loti; KEGG, K02005 YP_001947469.1 COG1136: ABC-type antimicrobial peptide transport system, ATPase component, Methanosarcina acetivorans str.C2A; KEGG, K02003 YP_001947470.1 KEGG, K02004 YP_001947471.1 COG0577: ABC-type antimicrobial peptide transport system, permease component, Methanosarcina acetivorans str.C2A YP_001947472.1 COG3644: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001947473.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K03535 YP_001947474.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Ralstonia solanacearum; KEGG, K01706 YP_001947475.1 COG4654: Cytochrome c551/c552, Ralstonia solanacearum YP_001947476.1 COG2823: Predicted periplasmic or secreted lipoprotein, Ralstonia solanacearum YP_001947477.1 COG0279: Phosphoheptose isomerase, Pseudomonas aeruginosa; KEGG, K03271 YP_001947478.1 COG0792: Predicted endonuclease distantly related to archaeal Holliday junction resolvase, Escherichia coli O157:H7; KEGG, K07460 YP_001947479.1 COG0313: Predicted methyltransferases, Ralstonia solanacearum; KEGG, K07056 YP_001947480.1 COG0797: Lipoproteins, Ralstonia solanacearum; KEGG, K03642 YP_001947481.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Ralstonia solanacearum; KEGG, K01069 YP_001947483.1 COG1522: Transcriptional regulators, Caulobacter vibrioides YP_001947484.1 COG0053: Predicted Co/Zn/Cd cation transporters, Ralstonia solanacearum YP_001947485.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001947487.1 COG0748: Putative heme iron utilization protein, Pseudomonas aeruginosa; KEGG, K07226 YP_001947488.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947489.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947490.1 COG2070: Dioxygenases related to 2-nitropropane dioxygenase, Staphylococcus aureus N315; KEGG, K00459 YP_001947491.1 COG0412: Dienelactone hydrolase and related enzymes, Caulobacter vibrioides; KEGG, K01061 YP_001947492.1 COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Deinococcus radiodurans; KEGG, K01426 YP_001947493.1 COG0685: 5,10-methylenetetrahydrofolate reductase, Ralstonia solanacearum; KEGG, K00297 YP_001947494.1 COG1950: Predicted membrane protein, Ralstonia solanacearum; KEGG, K08972 YP_001947495.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001947496.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001947497.1 COG0455: ATPases involved in chromosome partitioning, Vibrio cholerae; FlhG protein; KEGG, K04562 YP_001947498.1 positive regulator of class III flagellar genes YP_001947499.1 membrane protein involved in the flagellar export apparatus YP_001947500.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001947503.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_001947504.1 COG0784: FOG: CheY-like receiver, Yersinia pestis; CheY protein; KEGG, K03413 YP_001947505.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001947506.1 catalyzes the conversion of glutamine residues to glutamate on methyl-accepting chemotaxis receptors YP_001947507.1 COG1352: Methylase of chemotaxis methyl-accepting proteins, Ralstonia solanacearum; CheR protein; KEGG, K00575 YP_001947508.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K05874 YP_001947509.1 COG0835: Chemotaxis signal transduction protein, Salmonella typhimurium LT2; CheW protein; KEGG, K03408 YP_001947510.1 COG0643: Chemotaxis protein histidine kinase and related kinases, Ralstonia solanacearum; CheA protein; KEGG, K03407 YP_001947511.1 COG0784: FOG: CheY-like receiver, Pseudomonas aeruginosa; CheY protein; KEGG, K03413 YP_001947512.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001947513.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_001947514.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_001947515.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_001947516.1 COG0438: Glycosyltransferase, Sinorhizobium meliloti; KEGG, K08256 YP_001947517.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001947518.1 porin involved in osmoregulation allowing water to move into and out of the cell in response to osmotic pressure YP_001947519.1 COG0561: Predicted hydrolases of the HAD superfamily, Vibrio cholerae; KEGG, K07024 YP_001947520.1 COG2971: Predicted N-acetylglucosamine kinase, Mesorhizobium loti; KEGG, K00884 YP_001947521.1 COG2818: 3-methyladenine DNA glycosylase, Ralstonia solanacearum; KEGG, K01246 YP_001947522.1 COG3182: Uncharacterized iron-regulated membrane protein, Pseudomonas aeruginosa YP_001947523.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001947524.1 COG1344: Flagellin and related hook-associated proteins, Pseudomonas aeruginosa; KEGG, K02406 YP_001947525.1 COG1345: Flagellar capping protein, Escherichia coli K12; KEGG, K02407 YP_001947528.1 COG3245: Cytochrome c5, Ralstonia solanacearum YP_001947529.1 COG0210: Superfamily I DNA and RNA helicases, Ralstonia solanacearum; KEGG, K03656; Rep protein YP_001947530.1 COG0673: Predicted dehydrogenases and related proteins, Yersinia pestis YP_001947532.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001947533.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001947534.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001947536.1 COG1760: L-serine deaminase, Ralstonia solanacearum; KEGG, K01752 YP_001947537.1 KEGG, K07062 YP_001947539.1 COG0028: Thiamine pyrophosphate-requiring enzymes; KEGG, K01652 YP_001947541.1 COG2207: AraC-type DNA-binding domain-containing proteins, Salmonella typhimurium LT2; KEGG, K04033 YP_001947543.1 COG1012: NAD-dependent aldehyde dehydrogenases, Deinococcus radiodurans; KEGG, K00128 YP_001947545.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001947546.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001947547.1 catalyzes the formation of acetaldehyde from ethanolamine YP_001947548.1 COG4303: Ethanolamine ammonia-lyase, large subunit, Ralstonia solanacearum; KEGG, K03735 YP_001947549.1 COG0531: Amino acid transporters, Clostridium acetobutylicum YP_001947551.1 KEGG, K07471 YP_001947553.1 COG2217: Cation transport ATPase, Pseudomonas aeruginosa; KEGG, K01532 YP_001947554.1 COG0789: Predicted transcriptional regulators, Pseudomonas aeruginosa YP_001947556.1 COG0277: FAD/FMN-containing dehydrogenases, Sinorhizobium meliloti; KEGG, K00102 YP_001947557.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001947558.1 catalyzes the transfer of an amino moiety YP_001947560.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K09456 YP_001947561.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947562.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_001947563.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity YP_001947564.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001947565.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Ralstonia solanacearum; KEGG, K01713 YP_001947567.1 COG0318: Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II, Ralstonia solanacearum; KEGG, K01897 YP_001947568.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001947569.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001947570.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001947571.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001947572.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001947573.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001947574.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001947575.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001947576.1 KEGG, K02116 YP_001947578.1 COG0471: Di- and tricarboxylate transporters, Ralstonia solanacearum YP_001947579.1 COG1475: Predicted transcriptional regulators, Ralstonia solanacearum; KEGG, K03497; ParB1 protein YP_001947580.1 COG1192: ATPases involved in chromosome partitioning, Ralstonia solanacearum; KEGG, K03496; ParA1 protein YP_001947581.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001947582.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001947583.1 COG0410: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001947584.1 COG4177: ABC-type branched-chain amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K01995 YP_001947585.1 COG0559: Branched-chain amino acid ABC-type transport system, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001947586.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947588.1 COG4177: ABC-type branched-chain amino acid transport system, permease component, Ralstonia solanacearum; KEGG, K01998 YP_001947589.1 COG0559: Branched-chain amino acid ABC-type transport system, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001947590.1 COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947591.1 COG0410: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001947592.1 COG0411: ABC-type branched-chain amino acid transport systems, ATPase component, Ralstonia solanacearum; KEGG, K01995 YP_001947593.1 COG2303: Choline dehydrogenase and related flavoproteins, Ralstonia solanacearum; KEGG, K00108 YP_001947594.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947595.1 COG1437: Adenylate cyclase, class 2 (thermophilic), Ralstonia solanacearum YP_001947596.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001947597.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001947598.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001947600.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Mesorhizobium loti YP_001947601.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum YP_001947602.1 COG2940: Proteins containing SET domain, Ralstonia solanacearum; KEGG, K07117 YP_001947603.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Ralstonia solanacearum; KEGG, K00219 YP_001947604.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001947607.1 COG0582: Integrase, Ralstonia solanacearum YP_001947609.1 COG1396: transcriptional regulators, Ralstonia solanacearum; contains cupin sensor domain YP_001947610.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001947611.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001947612.1 COG1309: Transcriptional regulator, Nostoc sp. PCC 7120 YP_001947613.1 COG3558: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001947614.1 COG0473: Isocitrate/isopropylmalate dehydrogenase, Ralstonia solanacearum; KEGG, K00056 YP_001947615.1 COG0583: Transcriptional regulator, Escherichia coli K12 YP_001947618.1 COG1752: esterase of the alpha-beta hydrolase superfamily, Ralstonia solanacearum; KEGG, K07001 YP_001947619.1 catalyzes the formation of acetoacetate from 3-hydroxybutyrate YP_001947620.1 converts acetoacetate to acetone and carbon dioxide YP_001947621.1 COG0671: Membrane-associated phospholipid phosphatase, Ralstonia solanacearum YP_001947623.1 COG2375: Siderophore-interacting protein, Deinococcus radiodurans; KEGG, K07229 YP_001947624.1 COG1695: transcriptional regulators, Ralstonia solanacearum YP_001947626.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00065 YP_001947627.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Pseudomonas aeruginosa; KEGG, K00008 YP_001947628.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001947630.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001947631.1 COG0667: oxidoreductases (related to aryl-alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K05882 YP_001947632.1 COG1279: Lysine efflux permease, Brucella melitensis; KEGG, K06895 YP_001947633.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001947634.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Neisseria meningitidis Z2491; KEGG, K01420 YP_001947635.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001947638.1 KEGG, K00640 YP_001947639.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum YP_001947640.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001947641.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; PcaR protein YP_001947642.1 catalyzes the formation of protocatechuate from 4-hydroxybenzoate YP_001947643.1 COG1788: Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit, Ralstonia solanacearum; KEGG, K01031 YP_001947644.1 COG2057: Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit, Ralstonia solanacearum; KEGG, K01032 YP_001947645.1 Catalyzes the cycloisomerization of cis,cis-muconate YP_001947646.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Ralstonia solanacearum; KEGG, K01055 YP_001947647.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit, Ralstonia solanacearum; KEGG, K01607 YP_001947648.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001947650.1 COG1280: threonine efflux protein, Sinorhizobium meliloti YP_001947651.1 COG1937: Uncharacterized protein conserved in bacteria, Agrobacterium tumefaciens strain C58; conserved in bacteria YP_001947652.1 COG1230: Co/Zn/Cd efflux system component, Sinorhizobium meliloti; KEGG, K03295 YP_001947655.1 COG0406: Fructose-2,6-bisphosphatase, Pseudomonas aeruginosa YP_001947656.1 COG3173: aminoglycoside phosphotransferase, Mesorhizobium loti; KEGG, K06979 YP_001947657.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00079 YP_001947658.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00059 YP_001947659.1 COG1960: Acyl-CoA dehydrogenases, Deinococcus radiodurans; KEGG, K00249 YP_001947660.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947661.1 COG1802: Transcriptional regulators, Sinorhizobium meliloti YP_001947662.1 COG3938: Proline racemase, Agrobacterium tumefaciens strain C58; KEGG, K01777 YP_001947663.1 COG1012: NAD-dependent aldehyde dehydrogenases, Bacillus subtilis; KEGG, K00130 YP_001947664.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Mesorhizobium loti; KEGG, K00285 YP_001947665.1 COG3938: Proline racemase, Mesorhizobium loti; KEGG, K01777 YP_001947666.1 COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase, Agrobacterium tumefaciens strain C58; KEGG, K01714 YP_001947667.1 COG0765: ABC-type amino acid transporter, permease component, Listeria innocua; KEGG, K02029 YP_001947668.1 COG0765: ABC-type amino acid transporter, permease component, Bacillus halodurans; KEGG, K02029 YP_001947669.1 COG1126: ABC-type polar amino acid transporter, ATPase component, Thermotoga maritima; KEGG, K02028 YP_001947671.1 contains C-terminal Zn finger domain YP_001947672.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001947673.1 COG2200: FOG: EAL domain, Nostoc sp. PCC 7120 YP_001947676.1 COG0234: Co-chaperonin GroES (HSP10), Neisseria meningitidis MC58; KEGG, K04078 YP_001947677.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth YP_001947678.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Mycobacterium tuberculosis CDC1551 YP_001947679.1 COG3546: Mn-containing catalase, Pseudomonas aeruginosa; KEGG, K07217 YP_001947680.1 COG1914: Mn2+ and Fe2+ transporters of the NRAMP family, Deinococcus radiodurans; KEGG, K03322 YP_001947682.1 COG1252: NADH dehydrogenase, FAD-containing subunit, Ralstonia solanacearum; KEGG, K00356 YP_001947683.1 COG0583: Transcriptional regulator, Synechocystis YP_001947685.1 COG2207: AraC-type DNA-binding domain-containing proteins, Mesorhizobium loti YP_001947686.1 COG0702: nucleoside-diphosphate-sugar epimerases, Mesorhizobium loti YP_001947687.1 COG3135: Uncharacterized protein involved in benzoate metabolism, Pseudomonas aeruginosa; KEGG, K05782 YP_001947688.1 COG3239: Fatty acid desaturase, Pseudomonas aeruginosa YP_001947689.1 COG3221: ABC-type phosphate/phosphonate transporter, periplasmic component, Pseudomonas aeruginosa YP_001947690.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001947693.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947694.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001947696.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Caulobacter vibrioides; KEGG, K00059 YP_001947697.1 COG0496: acid phosphatase, Brucella melitensis; KEGG, K03787 YP_001947698.1 COG4541: membrane protein, Ralstonia solanacearum YP_001947699.1 COG1296: branched-chain amino acid permease (azaleucine resistance), Ralstonia solanacearum YP_001947700.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001947702.1 COG4390: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947703.1 COG0477: Permeases of the major facilitator superfamily, Xylella fastidiosa 9a5c YP_001947704.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Bacillus halodurans; typically associated with flavoprotein oxygenase YP_001947705.1 COG0526: Thiol-disulfide isomerase and thioredoxins, Pseudomonas aeruginosa; KEGG, K03671 YP_001947706.1 COG0432: Uncharacterized conserved protein, Synechocystis YP_001947707.1 COG0642: Signal transduction histidine kinase, Mesorhizobium loti YP_001947710.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07677; RcsC protein YP_001947712.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Pseudomonas aeruginosa; KEGG, K07687; RcsB protein YP_001947713.1 KEGG, K07677; RcsC protein YP_001947714.1 catalyzes conversion of 1-aminocyclopropane-1-carboxylate to ammonia and alpha-ketobutyrate YP_001947715.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001947723.1 catalyzes the formation of acetate from pyruvate YP_001947725.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001947726.1 COG4949: Uncharacterized membrane-anchored protein conserved in bacteria, Agrobacterium tumefaciens strain C58 YP_001947728.1 COG1012: NAD-dependent aldehyde dehydrogenases, Bacillus subtilis; KEGG, K00130 YP_001947729.1 COG0010: Arginase/agmatinase/formimionoglutamate hydrolase, arginase, Pseudomonas aeruginosa; KEGG, K01480 YP_001947732.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa YP_001947733.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947734.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; KEGG, K08194 YP_001947735.1 COG2374: extracellular nuclease, Pseudomonas aeruginosa; KEGG, K07004 YP_001947736.1 COG2939: Carboxypeptidase C (cathepsin A), Ralstonia solanacearum YP_001947738.1 COG1104: Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes, Pseudomonas aeruginosa; KEGG, K04487 YP_001947739.1 COG3503: membrane protein, Pseudomonas aeruginosa YP_001947740.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001947741.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Sinorhizobium meliloti YP_001947742.1 COG4566: Response regulator, Agrobacterium tumefaciens strain C58 YP_001947743.1 COG0642: Signal transduction histidine kinase, Agrobacterium tumefaciens strain C58; HydH protein; KEGG, K07709 YP_001947746.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Mesorhizobium loti; KEGG, K00433 YP_001947748.1 COG1064: Zn-dependent alcohol dehydrogenases, Ralstonia solanacearum; KEGG, K00001 YP_001947750.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Mesorhizobium loti YP_001947751.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Pseudomonas aeruginosa YP_001947752.1 COG1249: Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes, Agrobacterium tumefaciens strain C58; KEGG, K00520 YP_001947753.1 COG1733: transcriptional regulators, Mesorhizobium loti YP_001947755.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti YP_001947757.1 COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains, Ralstonia solanacearum; KEGG, K00820 YP_001947758.1 COG1522: Transcriptional regulators, Mesorhizobium loti YP_001947759.1 COG0350: Methylated DNA-protein cysteine methyltransferase, Ralstonia solanacearum; KEGG, K00567 YP_001947760.1 COG2169: Adenosine deaminase, Ralstonia solanacearum; KEGG, K00567 YP_001947761.1 COG0477: Permeases of the major facilitator superfamily, Caulobacter vibrioides; KEGG, K08191 YP_001947762.1 COG1609: Transcriptional regulators, Vibrio cholerae YP_001947763.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum; KEGG, K01784 YP_001947764.1 COG5470: Uncharacterized conserved protein, Mesorhizobium loti YP_001947766.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa YP_001947767.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947770.1 KEGG, K04065 YP_001947772.1 COG2202: FOG: PAS/PAC domain, Pseudomonas aeruginosa; contains two PAS domains and HTH DNA-binding motif YP_001947774.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947775.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Ralstonia solanacearum; KEGG, K00301 YP_001947777.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001947778.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00825 YP_001947780.1 COG0583: Transcriptional regulator, Mesorhizobium loti; KEGG, K03566 YP_001947781.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti; KEGG, K00059 YP_001947782.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Mesorhizobium loti YP_001947784.1 COG1280: threonine efflux protein, Escherichia coli O157:H7; KEGG, K05835 YP_001947785.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947786.1 COG1473: Metal-dependent amidase/aminoacylase/carboxypeptidase, Pseudomonas aeruginosa; KEGG, K01451 YP_001947787.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001947788.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001947789.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Mesorhizobium loti YP_001947790.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001947791.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001947792.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947793.1 involved in heme utilization or adhesion YP_001947794.1 COG2831: Hemolysin activation/secretion protein, Ralstonia solanacearum YP_001947795.1 COG3119: Arylsulfatase A and related enzymes, Pseudomonas aeruginosa; KEGG, K01130 YP_001947796.1 COG1262: Uncharacterized conserved protein, Caulobacter vibrioides YP_001947797.1 COG1464: ABC-type metal ion transporter, periplasmic component/surface antigen, Ralstonia solanacearum YP_001947799.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947800.1 COG4336: Uncharacterized conserved protein, Bacillus subtilis YP_001947801.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001947802.1 COG0145: N-methylhydantoinase A/acetone carboxylase, beta subunit, Mycobacterium tuberculosis H37Rv; KEGG, K01469 YP_001947803.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_001947804.1 regulator of pathogenicity factor RpfF; involved in synthesis of a diffusible signal factor involved in the regulation of extracellular enzymes YP_001947809.1 COG1305: Transglutaminase-like enzymes, cysteine proteases, Xylella fastidiosa 9a5c YP_001947811.1 COG2207: AraC-type DNA-binding domain-containing proteins, Mesorhizobium loti YP_001947812.1 COG2814: Arabinose efflux permease, Mesorhizobium loti; KEGG, K03445 YP_001947813.1 COG2513: PEP phosphonomutase and related enzymes, Sinorhizobium meliloti YP_001947814.1 COG1846: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001947816.1 COG0625: Glutathione S-transferase, Sinorhizobium meliloti; KEGG, K00799 YP_001947818.1 COG0443: Molecular chaperone, Vibrio cholerae YP_001947819.1 COG0443: Molecular chaperone, Vibrio cholerae YP_001947820.1 COG2128: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947821.1 COG4950: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001947822.1 COG2072: flavoprotein involved in K+ transport, Ralstonia solanacearum; involved in K+ transport YP_001947823.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947824.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001947825.1 COG0559: Branched-chain amino acid ABC-type transporter, permease components, Streptococcus pneumoniae TIGR4 YP_001947826.1 COG0411: ABC-type branched-chain amino acid transporters, ATPase component, Streptococcus pneumoniae TIGR4 YP_001947827.1 COG0410: ABC-type branched-chain amino acid transporters, ATPase component, Thermotoga maritima; KEGG, K01996 YP_001947828.1 COG0642: Signal transduction histidine kinase, Xylella fastidiosa 9a5c YP_001947829.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Xylella fastidiosa 9a5c; KEGG, K07774; TctD protein YP_001947830.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Ralstonia solanacearum; KEGG, K02051 YP_001947831.1 COG0477: Permeases of the major facilitator superfamily, Caulobacter vibrioides YP_001947833.1 COG0671: Membrane-associated phospholipid phosphatase, Xylella fastidiosa 9a5c YP_001947834.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Yersinia pestis YP_001947835.1 COG0477: Permeases of the major facilitator superfamily, Sinorhizobium meliloti YP_001947836.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Pseudomonas aeruginosa; KEGG, K00484 YP_001947837.1 COG4566: Response regulator, Pseudomonas aeruginosa YP_001947838.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti YP_001947839.1 COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Pyrobaculum aerophilum; KEGG, K01426 YP_001947842.1 COG1960: Acyl-CoA dehydrogenases, Mycobacterium tuberculosis CDC1551 YP_001947843.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936 YP_001947846.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Pseudomonas aeruginosa; KEGG, K08689 YP_001947847.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2 YP_001947848.1 COG1960: Acyl-CoA dehydrogenases, Mycobacterium tuberculosis CDC1551 YP_001947849.1 COG1853: Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family, Pseudomonas aeruginosa; KEGG, K00484 YP_001947851.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947852.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947853.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Pseudomonas aeruginosa; KEGG, K07519 YP_001947854.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001947855.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001947856.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947857.1 COG2207: AraC-type DNA-binding domain-containing proteins, Ralstonia solanacearum YP_001947859.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001947860.1 COG0477: Permeases of the major facilitator superfamily, Corynebacterium glutamicum YP_001947861.1 KEGG, K02055 YP_001947862.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Mesorhizobium loti YP_001947863.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Mesorhizobium loti YP_001947864.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Mesorhizobium loti YP_001947865.1 COG1177: ABC-type spermidine/putrescine transporter, permease component II, Mesorhizobium loti; KEGG, K02053 YP_001947866.1 COG1176: ABC-type spermidine/putrescine transporter, permease component I, Mesorhizobium loti; KEGG, K02054 YP_001947867.1 COG3842: ABC-type spermidine/putrescine transporters, ATPase components, Agrobacterium tumefaciens strain C58; KEGG, K02052 YP_001947868.1 COG1414: Transcriptional regulator, Mesorhizobium loti YP_001947869.1 Enables the enzymatic reduction of mercuric ions to elemental mercury YP_001947871.1 COG1280: threonine efflux protein, Salmonella typhimurium LT2 YP_001947874.1 COG1360: Flagellar motor protein, Ralstonia solanacearum YP_001947880.1 COG0599: Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit, Pseudomonas aeruginosa; KEGG, K01607 YP_001947881.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Mesorhizobium loti; KEGG, K01259 YP_001947882.1 COG2072: flavoprotein involved in K+ transport, Caulobacter vibrioides; KEGG, K03379 YP_001947883.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K03366 YP_001947885.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001947886.1 COG0625: Glutathione S-transferase, Sinorhizobium meliloti; KEGG, K00799 YP_001947888.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Ralstonia solanacearum; KEGG, K02014 YP_001947889.1 COG3201: Nicotinamide mononucleotide transporter, Pseudomonas aeruginosa; KEGG, K03811 YP_001947891.1 COG2873: O-acetylhomoserine sulfhydrylase, Pseudomonas aeruginosa; KEGG, K01740 YP_001947892.1 COG4122: O-methyltransferase, Mesorhizobium loti; KEGG, K00599 YP_001947893.1 COG0500: SAM-dependent methyltransferases, Mesorhizobium loti YP_001947894.1 COG1280: threonine efflux protein, Mesorhizobium loti YP_001947895.1 COG2207: AraC-type DNA-binding domain-containing proteins, Mesorhizobium loti YP_001947897.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; CeoR protein YP_001947898.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947899.1 COG0473: Isocitrate/isopropylmalate dehydrogenase, Ralstonia solanacearum; KEGG, K00056 YP_001947900.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947902.1 COG1457: Purine-cytosine permease and related proteins, Pseudomonas aeruginosa YP_001947903.1 COG0388: amidohydrolase, Pseudomonas aeruginosa YP_001947907.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_001947908.1 COG1289: membrane protein, Ralstonia solanacearum YP_001947909.1 COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain YP_001947910.1 COG0833: Amino acid transporters, Ralstonia solanacearum; KEGG, K03293 YP_001947912.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Deinococcus radiodurans; KEGG, K01259 YP_001947915.1 COG1819: Glycosyl transferases, related to UDP-glucuronosyltransferase, Saccharomyces cerevisiae YP_001947916.1 COG2188: Transcriptional regulators, Ralstonia solanacearum; KEGG, K05836 YP_001947917.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Salmonella typhimurium LT2; KEGG, K02030 YP_001947918.1 COG4215: ABC-type arginine transporter, permease component, Pseudomonas aeruginosa; KEGG, K02029 YP_001947919.1 COG4160: ABC-type arginine/histidine transporter, permease component, Yersinia pestis; KEGG, K02029 YP_001947920.1 COG4598: ABC-type histidine transporter, ATPase component, Pseudomonas aeruginosa; KEGG, K02028 YP_001947923.1 COG1291: Flagellar motor component, Pseudomonas aeruginosa; KEGG, K02556 YP_001947924.1 COG1360: Flagellar motor protein, Pseudomonas aeruginosa; KEGG, K02557 YP_001947925.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03406 YP_001947926.1 COG1280: threonine efflux protein, Sinorhizobium meliloti YP_001947927.1 COG0583: Transcriptional regulator, Bacillus halodurans YP_001947928.1 COG1228: Imidazolonepropionase and related amidohydrolases, Saccharomyces cerevisiae YP_001947929.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K03762 YP_001947930.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947931.1 COG3958: Transketolase, C-terminal subunit, Mesorhizobium loti; KEGG, K00615; contains C-terminal regulatory molecule-binding domain YP_001947932.1 COG3959: Transketolase, N-terminal subunit, Mesorhizobium loti; KEGG, K00615 YP_001947933.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001947934.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti; KEGG, K00059 YP_001947935.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001947936.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947937.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Mesorhizobium loti; KEGG, K00020 YP_001947938.1 COG1012: NAD-dependent aldehyde dehydrogenases, Agrobacterium tumefaciens strain C58; KEGG, K00130 YP_001947940.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001947941.1 KEGG, K02020 YP_001947942.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2 YP_001947944.1 COG1280: threonine efflux protein, Escherichia coli O157:H7; KEGG, K05835 YP_001947945.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001947946.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001947947.1 COG1566: Multidrug resistance efflux pump, Mesorhizobium loti YP_001947949.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001947951.1 COG1679: Uncharacterized conserved protein, Mesorhizobium loti; KEGG, K09123 YP_001947952.1 COG1786: Uncharacterized conserved protein, Mesorhizobium loti; KEGG, K09128 YP_001947953.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum YP_001947955.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001947956.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Pseudomonas aeruginosa; KEGG, K00219 YP_001947958.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001947959.1 COG2249: NADPH-quinone reductase (modulator of drug activity B), Pseudomonas aeruginosa; KEGG, K00355 YP_001947960.1 COG4829: Muconolactone delta-isomerase, Pseudomonas aeruginosa; KEGG, K03464 YP_001947961.1 COG3485: Protocatechuate 3,4-dioxygenase beta subunit, Pseudomonas aeruginosa; KEGG, K03381 YP_001947962.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Pseudomonas aeruginosa; KEGG, K01856 YP_001947963.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa; CatR protein YP_001947964.1 AndR protein; COG2207: AraC-type DNA-binding domain-containing proteins, Ralstonia solanacearum YP_001947965.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Ralstonia solanacearum; KEGG, K05708 YP_001947966.1 KEGG, K05709 YP_001947967.1 COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases, Ralstonia solanacearum; KEGG, K05710 YP_001947968.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Sinorhizobium meliloti; KEGG, K00529 YP_001947969.1 COG2733: membrane protein, Salmonella typhimurium LT2 YP_001947970.1 COG3636: transcriptional regulator, Ralstonia solanacearum YP_001947971.1 COG3657: Uncharacterized protein conserved in bacteria, Xylella fastidiosa 9a5c YP_001947972.1 catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis YP_001947973.1 COG1012: NAD-dependent aldehyde dehydrogenases, Aquifex aeolicus; KEGG, K00155 YP_001947974.1 COG0025: NhaP-type Na+/H+ and K+/H+ antiporters, Agrobacterium tumefaciens strain C58; KEGG, K03316 YP_001947975.1 contains signal receiving and histidine kinase domains YP_001947976.1 COG0840: Methyl-accepting chemotaxis protein, Pseudomonas aeruginosa; KEGG, K03406 YP_001947977.1 COG0835: Chemotaxis signal transduction protein, Pseudomonas aeruginosa; CheW protein; KEGG, K03408 YP_001947978.1 COG1352: Methylase of chemotaxis methyl-accepting proteins, Ralstonia solanacearum; CheR protein; KEGG, K00575 YP_001947979.1 COG0835: Chemotaxis signal transduction protein, Mesorhizobium loti; CheW protein; KEGG, K03408 YP_001947980.1 COG0643: Chemotaxis protein histidine kinase and related kinases, Mesorhizobium loti; CheA protein; KEGG, K03407 YP_001947981.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001947982.1 COG0038: Chloride channel protein EriC, Ralstonia solanacearum YP_001947983.1 COG1132: ABC-type multidrug transporter, ATPase and permease components, Mesorhizobium loti; KEGG, K06021 YP_001947984.1 COG2837: iron-dependent peroxidase, Pseudomonas aeruginosa; KEGG, K07223 YP_001947985.1 KEGG, K07397 YP_001947987.1 COG1914: Mn2+ and Fe2+ transporters of the NRAMP family, Ralstonia solanacearum; KEGG, K03322 YP_001947989.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Caulobacter vibrioides; KEGG, K00059 YP_001947991.1 COG0628: permease, Pseudomonas aeruginosa YP_001947992.1 COG2930: Uncharacterized conserved protein, Ralstonia solanacearum YP_001947995.1 COG3795: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001947996.1 COG3607: lactoylglutathione lyase, Bacillus halodurans; KEGG, K07032 YP_001947997.1 COG4941: RNA polymerase sigma factor containing a TPR repeat domain, Ralstonia solanacearum YP_001947998.1 COG1592: Rubrerythrin, Sulfolobus solfataricus YP_001947999.1 COG0247: Fe-S oxidoreductase, Sulfolobus solfataricus; KEGG, K00113 YP_001948002.1 COG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971 YP_001948003.1 COG2148: Sugar transferases involved in lipopolysaccharide synthesis, Escherichia coli K12; KEGG, K03606 YP_001948004.1 COG1004: UDP-glucose 6-dehydrogenase, Ralstonia solanacearum; KEGG, K00012 YP_001948005.1 COG0394: Protein-tyrosine-phosphatase, Salmonella typhimurium LT2; KEGG, K01104 YP_001948006.1 COG1596: Periplasmic protein involved in polysaccharide export, Ralstonia solanacearum; KEGG, K01991 YP_001948007.1 COG3206: Uncharacterized protein involved in exopolysaccharide biosynthesis, Ralstonia solanacearum; KEGG, K00903 YP_001948008.1 COG0463: Glycosyltransferases involved in cell wall biogenesis, Nostoc sp. PCC 7120; involved in cell wall biogenesis YP_001948011.1 COG0438: Glycosyltransferase, Nostoc sp. PCC 7120 YP_001948012.1 COG0438: Glycosyltransferase, Nostoc sp. PCC 7120; KEGG, K08256 YP_001948013.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001948014.1 COG1733: transcriptional regulators, Pseudomonas aeruginosa YP_001948015.1 COG0477: Permeases of the major facilitator superfamily, Caulobacter vibrioides; KEGG, K08166 YP_001948016.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001948017.1 COG0545: FKBP-type peptidyl-prolyl cis-trans isomerases 1, Ralstonia solanacearum; KEGG, K01802 YP_001948018.1 COG3687: metal-dependent hydrolase, Pseudomonas aeruginosa; KEGG, K07044 YP_001948019.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001948021.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Salmonella typhimurium LT2; KEGG, K02030 YP_001948024.1 COG0639: Diadenosine tetraphosphatase and related serine/threonine protein phosphatases, Escherichia coli O157:H7; KEGG, K07313 YP_001948025.1 COG4291: membrane protein, Ralstonia solanacearum YP_001948026.1 COG0500: SAM-dependent methyltransferases, Agrobacterium tumefaciens strain C58 YP_001948027.1 COG0296: 1,4-alpha-glucan branching enzyme, Ralstonia solanacearum; KEGG, K01236 YP_001948028.1 COG0352: Thiamine monophosphate synthase, Ralstonia solanacearum; KEGG, K00788 YP_001948029.1 COG1253: Hemolysins and related proteins containing CBS domains, Pseudomonas aeruginosa YP_001948030.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum YP_001948031.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Pseudomonas aeruginosa YP_001948032.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001948034.1 COG3025: Uncharacterized conserved protein, Caulobacter vibrioides YP_001948035.1 COG2005: N-terminal domain of molybdenum-binding protein, Ralstonia solanacearum; KEGG, K02019 YP_001948036.1 COG1118: ABC-type sulfate/molybdate transporters, ATPase component, Ralstonia solanacearum; KEGG, K02017 YP_001948037.1 COG4149: ABC-type molybdate transporter, permease component, Ralstonia solanacearum; KEGG, K02018 YP_001948038.1 COG0725: ABC-type molybdate transporter, periplasmic component, Ralstonia solanacearum; KEGG, K02020 YP_001948040.1 COG3509: Poly(3-hydroxybutyrate) depolymerase, Ralstonia solanacearum YP_001948042.1 COG1764: redox protein, regulator of disulfide bond formation, Ralstonia solanacearum; KEGG, K04063; OsmC protein YP_001948043.1 COG1846: Transcriptional regulators, Pseudomonas aeruginosa YP_001948045.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_001948047.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_001948058.1 COG1396: transcriptional regulators, Ralstonia solanacearum YP_001948061.1 COG3500: Phage protein D, Salmonella typhimurium LT2; KEGG, K06905 YP_001948062.1 COG3499: Phage protein U, Ralstonia solanacearum; KEGG, K06906 YP_001948063.1 COG5283: Phage-related tail protein, Salmonella typhimurium LT2 YP_001948066.1 COG3498: Phage tail tube protein FII, Ralstonia solanacearum; KEGG, K06908 YP_001948067.1 COG3497: Phage tail sheath protein FI, Ralstonia solanacearum; KEGG, K06907 YP_001948068.1 COG0863: DNA modification methylase, Xylella fastidiosa 9a5c; KEGG, K07319 YP_001948072.1 COG4385: Bacteriophage P2-related tail formation protein, Xylella fastidiosa 9a5c YP_001948073.1 COG3948: Phage-related baseplate assembly protein, Ralstonia solanacearum YP_001948074.1 COG3628: Phage baseplate assembly protein W, Ralstonia solanacearum; KEGG, K06903 YP_001948075.1 COG4540: Phage P2 baseplate assembly protein gpV, Ralstonia solanacearum YP_001948080.1 COG3409: peptidoglycan-binding domain-containing protein, Ralstonia solanacearum YP_001948089.1 COG5484: Uncharacterized conserved protein, Ralstonia solanacearum YP_001948090.1 COG5518: Bacteriophage capsid portal protein, Ralstonia solanacearum YP_001948091.1 COG3344: Retron-type reverse transcriptase, Nostoc sp. PCC 7120 YP_001948092.1 COG1396: transcriptional regulators, Nostoc sp. PCC 7120 YP_001948094.1 COG1683: Uncharacterized conserved protein, Agrobacterium tumefaciens strain C58 YP_001948096.1 COG1611: Rossmann fold nucleotide-binding protein, Ralstonia solanacearum; KEGG, K06966 YP_001948097.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair YP_001948098.1 COG1252: NADH dehydrogenase, FAD-containing subunit, Ralstonia solanacearum; KEGG, K03885 YP_001948099.1 COG0412: Dienelactone hydrolase and related enzymes, Ralstonia solanacearum; KEGG, K01061 YP_001948100.1 COG2897: Rhodanese-related sulfurtransferase, Ralstonia solanacearum; KEGG, K01010 YP_001948101.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Ralstonia solanacearum; KEGG, K00499 YP_001948102.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_001948103.1 COG0142: Geranylgeranyl pyrophosphate synthase, Ralstonia solanacearum; KEGG, K00795 YP_001948104.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001948105.1 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis YP_001948106.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001948107.1 COG2081: flavoproteins, Ralstonia solanacearum; KEGG, K07007 YP_001948108.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001948109.1 COG1610: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09117 YP_001948110.1 synthesizes RNA primers at the replication forks YP_001948111.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_001948112.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Sinorhizobium meliloti YP_001948113.1 COG0477: Permeases of the major facilitator superfamily, Yersinia pestis YP_001948114.1 KEGG, K04102 YP_001948116.1 COG0157: Nicotinate-nucleotide pyrophosphorylase, Ralstonia solanacearum; KEGG, K00767 YP_001948118.1 COG0673: dehydrogenases and related proteins, Brucella melitensis; OphB protein YP_001948119.1 OphA2 protein YP_001948122.1 COG0667: oxidoreductases (related to aryl-alcohol dehydrogenases), Xylella fastidiosa 9a5c; related to aryl-alcohol dehydrogenases YP_001948123.1 COG1064: Zn-dependent alcohol dehydrogenases, Xylella fastidiosa 9a5c; KEGG, K00001 YP_001948124.1 COG2814: Arabinose efflux permease, Xylella fastidiosa 9a5c YP_001948125.1 COG0583: Transcriptional regulator, Xylella fastidiosa 9a5c YP_001948126.1 OrfA YP_001948127.1 OrfB YP_001948129.1 COG1917: Uncharacterized conserved protein, contains double-stranded beta-helix domain, Sinorhizobium meliloti YP_001948130.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948136.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948137.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transporter, ATPase component, Sinorhizobium meliloti; KEGG, K02049 YP_001948138.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transporter, permease component, Pseudomonas aeruginosa; KEGG, K02050 YP_001948140.1 COG0028: Thiamine pyrophosphate-requiring enzymes YP_001948141.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa YP_001948142.1 KEGG, K04102 YP_001948143.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948144.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K02660; PilJ protein YP_001948151.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948152.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948154.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948157.1 KEGG, K00504 YP_001948158.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum; KEGG, K01999 YP_001948159.1 COG0559: Branched-chain amino acid ABC-type transporter, permease components, Ralstonia solanacearum; KEGG, K01997 YP_001948160.1 COG4177: ABC-type branched-chain amino acid transporter, permease component, Ralstonia solanacearum; KEGG, K01998 YP_001948161.1 COG0411: ABC-type branched-chain amino acid transporters, ATPase component, Ralstonia solanacearum; KEGG, K01995 YP_001948162.1 COG0410: ABC-type branched-chain amino acid transporters, ATPase component, Ralstonia solanacearum; KEGG, K01996 YP_001948164.1 COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Ralstonia solanacearum YP_001948166.1 KEGG, K00504 YP_001948167.1 COG1113: Gamma-aminobutyrate permease and related permeases, Pseudomonas aeruginosa; KEGG, K03293 YP_001948168.1 C-terminal portion YP_001948170.1 OrfB YP_001948171.1 OrfA YP_001948177.1 OrfA YP_001948178.1 OrfB YP_001948180.1 OrfA YP_001948181.1 OrfB YP_001948182.1 OrfA YP_001948186.1 COG4422: Bacteriophage protein gp37, Mycobacterium tuberculosis CDC1551 YP_001948190.1 OrfB YP_001948192.1 OrfA YP_001948193.1 OrfB YP_001948204.1 COG1204: Superfamily II helicase, Methanosarcina acetivorans str.C2A; contains a peptidase domain YP_001948206.1 COG0684: Demethylmenaquinone methyltransferase, Agrobacterium tumefaciens strain C58 YP_001948207.1 COG0111: Phosphoglycerate dehydrogenase and related dehydrogenases, Agrobacterium tumefaciens strain C58; KEGG, K00058 YP_001948208.1 COG3386: Gluconolactonase, Ralstonia solanacearum; KEGG, K01053 YP_001948209.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948210.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948211.1 COG3618: metal-dependent hydrolase of the TIM-barrel fold, Mesorhizobium loti YP_001948212.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948213.1 COG0477: Permeases of the major facilitator superfamily, Deinococcus radiodurans YP_001948214.1 COG0477: Permeases of the major facilitator superfamily, Brucella melitensis YP_001948215.1 COG3618: metal-dependent hydrolase of the TIM-barrel fold, Yersinia pestis YP_001948216.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum YP_001948218.1 COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain YP_001948219.1 COG0415: Deoxyribodipyrimidine photolyase, Mesorhizobium loti; KEGG, K01669 YP_001948220.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Sinorhizobium meliloti; KEGG, K00121 YP_001948221.1 COG4122: O-methyltransferase, Pseudomonas aeruginosa YP_001948222.1 COG1309: Transcriptional regulator, Pseudomonas aeruginosa YP_001948226.1 COG1538: Outer membrane protein, Caulobacter vibrioides YP_001948227.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948228.1 COG1566: Multidrug resistance efflux pump, Ralstonia solanacearum; KEGG, K03543 YP_001948229.1 COG1309: Transcriptional regulator, Salmonella typhimurium LT2 YP_001948230.1 COG0668: Small-conductance mechanosensitive channel, Sinorhizobium meliloti; KEGG, K03442 YP_001948231.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Ralstonia solanacearum YP_001948232.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001948234.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001948237.1 COG0739: Membrane proteins related to metalloendopeptidases, Ralstonia solanacearum; KEGG, K06194; NlpD protein YP_001948239.1 COG3038: Cytochrome B561, Pseudomonas aeruginosa YP_001948241.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Pseudomonas aeruginosa; KEGG, K02014 YP_001948242.1 COG1075: acetyltransferases and hydrolases with the alpha/beta hydrolase fold, Xylella fastidiosa 9a5c; KEGG, K01046 YP_001948243.1 acts as a molecular chaperone to fold and export lipase A YP_001948244.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00375; contains aminotransferase domain YP_001948245.1 COG3842: ABC-type spermidine/putrescine transporters, ATPase components, Ralstonia solanacearum; KEGG, K02052 YP_001948246.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Ralstonia solanacearum; KEGG, K02055 YP_001948247.1 COG1176: ABC-type spermidine/putrescine transporter, permease component I, Ralstonia solanacearum; KEGG, K02054 YP_001948248.1 COG1177: ABC-type spermidine/putrescine transporter, permease component II, Ralstonia solanacearum; KEGG, K02053 YP_001948249.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli K12; KEGG, K08169 YP_001948250.1 COG4934: protease, Clostridium acetobutylicum; KEGG, K05998 YP_001948251.1 COG0640: transcriptional regulators, Sinorhizobium meliloti YP_001948252.1 COG3832: Uncharacterized conserved protein, Mesorhizobium loti YP_001948253.1 COG5649: Uncharacterized conserved protein, Mesorhizobium loti YP_001948254.1 catalyzes the conversion of citrate to isocitrate YP_001948255.1 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C YP_001948257.1 COG2301: Citrate lyase beta subunit, Ralstonia solanacearum; KEGG, K01644 YP_001948258.1 catalyzes the oxidation of malate to oxaloacetate YP_001948259.1 COG2188: Transcriptional regulators, Ralstonia solanacearum; KEGG, K03710 YP_001948260.1 COG2009: Succinate dehydrogenase/fumarate reductase, cytochrome b subunit, Ralstonia solanacearum; KEGG, K00241 YP_001948261.1 COG2142: Succinate dehydrogenase, hydrophobic anchor subunit, Ralstonia solanacearum; KEGG, K00242 YP_001948262.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001948263.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001948264.1 COG2938: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K09159 YP_001948265.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001948266.1 COG2207: AraC-type DNA-binding domain-containing proteins, Agrobacterium tumefaciens strain C58 YP_001948267.1 COG0346: Lactoylglutathione lyase and related lyases, Agrobacterium tumefaciens strain C58 YP_001948269.1 COG1834: N-Dimethylarginine dimethylaminohydrolase, Pseudomonas aeruginosa; KEGG, K01482 YP_001948270.1 COG1522: Transcriptional regulators, Mesorhizobium loti YP_001948271.1 COG0833: Amino acid transporters, Ralstonia solanacearum; LysP protein YP_001948272.1 KEGG, K00799 YP_001948276.1 COG1858: Cytochrome c peroxidase, Ralstonia solanacearum; KEGG, K00428 YP_001948277.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001948279.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001948280.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001948281.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_001948282.1 COG3170: Tfp pilus assembly protein FimV, Ralstonia solanacearum YP_001948283.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001948284.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis YP_001948285.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001948286.1 COG0863: DNA modification methylase, Ralstonia solanacearum; KEGG, K07319 YP_001948287.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001948288.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_001948289.1 COG0285: Folylpolyglutamate synthase, Ralstonia solanacearum; KEGG, K01930 YP_001948290.1 COG3147: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; KEGG, K03749 YP_001948291.1 COG1286: Uncharacterized membrane protein, required for colicin V production, Ralstonia solanacearum; KEGG, K03558 YP_001948292.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001948293.1 catalyzes the conversion of O-succinylhomoserine into homocysteine YP_001948294.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Xylella fastidiosa 9a5c; KEGG, K01711 YP_001948295.1 COG1089: GDP-D-mannose dehydratase, Xylella fastidiosa 9a5c; KEGG, K01711 YP_001948299.1 COG0438: Glycosyltransferase, Agrobacterium tumefaciens strain C58 YP_001948302.1 COG1210: UDP-glucose pyrophosphorylase, Ralstonia solanacearum; KEGG, K00963 YP_001948303.1 COG1835: acyltransferases, Sinorhizobium meliloti YP_001948304.1 Bph2 protein YP_001948305.1 COG3865: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti YP_001948306.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948307.1 COG1295: membrane protein, Nostoc sp. PCC 7120; KEGG, K07058 YP_001948308.1 KEGG, K00122 YP_001948309.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Escherichia coli K12; KEGG, K00123 YP_001948310.1 COG0437: Fe-S-cluster-containing hydrogenase components 1, Pseudomonas aeruginosa; KEGG, K00124 YP_001948311.1 COG2864: Cytochrome b subunit of formate dehydrogenase, Pseudomonas aeruginosa; KEGG, K00127 YP_001948312.1 COG3058: Uncharacterized protein involved in formate dehydrogenase formation, Salmonella typhimurium LT2; KEGG, K02380 YP_001948313.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_001948314.1 COG3276: Selenocysteine-specific translation elongation factor, Pseudomonas aeruginosa; KEGG, K03833 YP_001948315.1 COG1752: esterase of the alpha-beta hydrolase superfamily, Mesorhizobium loti; KEGG, K07001 YP_001948316.1 KEGG, K03654; RecQ protein YP_001948317.1 COG1801: Uncharacterized conserved protein, Bacillus halodurans YP_001948318.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001948319.1 COG0251: translation initiation inhibitor, yjgF family, Sinorhizobium meliloti YP_001948320.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948321.1 COG1609: Transcriptional regulators, Agrobacterium tumefaciens strain C58; KEGG, K06145 YP_001948322.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001948323.1 COG3970: Fumarylacetoacetate (FAA) hydrolase, Yersinia pestis YP_001948325.1 COG2233: Xanthine/uracil permeases, Pseudomonas aeruginosa; KEGG, K03458 YP_001948326.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001948327.1 COG0554: Glycerol kinase, Deinococcus radiodurans; KEGG, K00864 YP_001948328.1 COG0578: Glycerol-3-phosphate dehydrogenase, Mycobacterium tuberculosis CDC1551; KEGG, K00111 YP_001948329.1 COG0277: FAD/FMN-containing dehydrogenases, Archaeoglobus fulgidus; KEGG, K00803 YP_001948330.1 COG1954: Glycerol-3-phosphate responsive antiterminator (mRNA-binding), Bacillus subtilis; KEGG, K02443 YP_001948332.1 COG1454: Alcohol dehydrogenase, class IV, Agrobacterium tumefaciens strain C58; KEGG, K00001 YP_001948333.1 COG2814: Arabinose efflux permease, Pseudomonas aeruginosa; KEGG, K08164 YP_001948334.1 COG3554: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001948335.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001948336.1 COG2343: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti; conserved in bacteria YP_001948337.1 COG0747: ABC-type dipeptide transporter, periplasmic component, Pseudomonas aeruginosa; KEGG, K02035 YP_001948338.1 COG2175: taurine catabolism dioxygenase, Escherichia coli K12; KEGG, K03119 YP_001948339.1 COG2175: taurine catabolism dioxygenase, Pseudomonas aeruginosa; KEGG, K03119 YP_001948340.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transporter, ATPase component, Pseudomonas aeruginosa; KEGG, K02049 YP_001948342.1 KEGG, K02050 YP_001948343.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001948345.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa YP_001948346.1 COG0679: permeases, Brucella melitensis; KEGG, K07088 YP_001948347.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948349.1 contains GTPase activity YP_001948351.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948352.1 COG1846: Transcriptional regulators, Mesorhizobium loti YP_001948353.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; CoxL protein YP_001948357.1 COG3473: Maleate cis-trans isomerase, Ralstonia solanacearum; KEGG, K01799 YP_001948358.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Salmonella typhimurium LT2; KEGG, K00480 YP_001948359.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Pseudomonas aeruginosa; CoxS protein YP_001948360.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa YP_001948362.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Ralstonia solanacearum; KEGG, K00020 YP_001948363.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00140 YP_001948364.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948365.1 COG0583: Transcriptional regulator, Brucella melitensis YP_001948366.1 COG1011: hydrolase (HAD superfamily), Pseudomonas aeruginosa; KEGG, K01560 YP_001948367.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001948368.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00059 YP_001948369.1 COG2200: FOG: EAL domain, Ralstonia solanacearum YP_001948370.1 COG3706: Response regulator containing a CheY-like receiver domain and a GGDEF domain, Pseudomonas aeruginosa; KEGG, K02488 YP_001948371.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001948373.1 COG3819: membrane protein, Campylobacter jejuni YP_001948374.1 COG3817: membrane protein, Caulobacter vibrioides YP_001948376.1 COG1414: Transcriptional regulator, Escherichia coli K12 YP_001948377.1 COG2303: Choline dehydrogenase and related flavoproteins, Sinorhizobium meliloti; KEGG, K00108 YP_001948378.1 COG0477: Permeases of the major facilitator superfamily, Corynebacterium glutamicum YP_001948379.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti YP_001948380.1 COG1113: Gamma-aminobutyrate permease and related permeases, Bacillus subtilis; KEGG, K03293 YP_001948381.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Mesorhizobium loti; KEGG, K00122 YP_001948382.1 COG0437: Fe-S-cluster-containing hydrogenase components 1, Aquifex aeolicus; KEGG, K04014 YP_001948383.1 COG3302: DMSO reductase anchor subunit, Mesorhizobium loti; KEGG, K07308 YP_001948384.1 COG1414: Transcriptional regulator, Bacillus halodurans YP_001948385.1 COG0714: MoxR-like ATPases, Sinorhizobium meliloti; CobS protein; KEGG, K06050 YP_001948386.1 COG4547: Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase), Caulobacter vibrioides; CobT protein; KEGG, K06050 YP_001948388.1 COG0280: Phosphotransacetylase, Sinorhizobium meliloti; KEGG, K00625 YP_001948389.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_001948391.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Mesorhizobium loti; KEGG, K00825 YP_001948393.1 COG1012: NAD-dependent aldehyde dehydrogenases, Sinorhizobium meliloti; KEGG, K00131 YP_001948394.1 KEGG, K06999 YP_001948399.1 COG0784: FOG: CheY-like receiver, Pseudomonas aeruginosa; CheY protein; KEGG, K03413 YP_001948400.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001948401.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001948405.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Ralstonia solanacearum; KEGG, K00837 YP_001948406.1 KEGG, K01607 YP_001948407.1 COG3555: Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases, Ralstonia solanacearum; KEGG, K00476 YP_001948409.1 COG3634: Alkyl hydroperoxide reductase, large subunit, Pseudomonas aeruginosa; KEGG, K03387 YP_001948410.1 COG0450: Peroxiredoxin, Salmonella typhimurium LT2; KEGG, K03386 YP_001948412.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001948413.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum YP_001948415.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001948416.1 COG2010: Cytochrome c, mono- and diheme variants, Ralstonia solanacearum YP_001948419.1 COG0449: Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains, Ralstonia solanacearum; KEGG, K00820 YP_001948421.1 polysaccharide polymerase involved in biofilm formation; required for the synthesis of the beta-1,6-N-acetylglucosamine polysaccharide; PgaC; in Yersinia the HmsR protein is an inner membrane protein YP_001948422.1 COG0726: xylanase/chitin deacetylase, Ralstonia solanacearum YP_001948426.1 COG3188: P pilus assembly protein, porin PapC, Salmonella typhimurium LT2; PapC protein YP_001948428.1 COG3121: P pilus assembly protein, chaperone PapD, Salmonella typhimurium LT2 YP_001948431.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Sinorhizobium meliloti; KEGG, K01259 YP_001948432.1 COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase, Vibrio cholerae; KEGG, K00839 YP_001948433.1 COG0028: Thiamine pyrophosphate-requiring enzymes; KEGG, K06034; Ppd protein YP_001948434.1 COG2513: PEP phosphonomutase and related enzymes, Mesorhizobium loti; KEGG, K01841 YP_001948439.1 COG0427: Acetyl-CoA hydrolase, Caulobacter vibrioides; KEGG, K01067 YP_001948440.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti; KEGG, K03446 YP_001948441.1 COG1846: Transcriptional regulators, Mesorhizobium loti YP_001948443.1 COG0789: transcriptional regulators, Pseudomonas aeruginosa YP_001948445.1 COG0568: DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32), Ralstonia solanacearum; RpoS protein YP_001948447.1 contains a SH3 domain YP_001948448.1 OrfB YP_001948449.1 OrfA YP_001948451.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001948452.1 COG2055: Malate/L-lactate dehydrogenases, Pseudomonas aeruginosa; KEGG, K00025 YP_001948453.1 COG1012: NAD-dependent aldehyde dehydrogenases, Caulobacter vibrioides; KEGG, K00155 YP_001948454.1 COG0531: Amino acid transporters, Bacillus subtilis YP_001948455.1 COG3938: Proline racemase, Pseudomonas aeruginosa; KEGG, K01777 YP_001948456.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa YP_001948457.1 contains 2Fe-2S iron-sulfur cluster-binding domain YP_001948458.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Pseudomonas aeruginosa YP_001948459.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948460.1 COG3435: Gentisate 1,2-dioxygenase, Ralstonia solanacearum; KEGG, K00450 YP_001948461.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Ralstonia solanacearum; KEGG, K01557 YP_001948462.1 COG0625: Glutathione S-transferase, Ralstonia solanacearum; KEGG, K01800 YP_001948463.1 catalyzes the formation of catechol from salicylate YP_001948464.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08195 YP_001948466.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00825 YP_001948468.1 COG1858: Cytochrome c peroxidase, Ralstonia solanacearum YP_001948470.1 COG0500: SAM-dependent methyltransferases, Mesorhizobium loti YP_001948472.1 COG1292: Choline-glycine betaine transporter, Pasteurella multocida; KEGG, K02168 YP_001948473.1 COG1737: Transcriptional regulators, Ralstonia solanacearum YP_001948474.1 COG1446: Asparaginase, Ralstonia solanacearum; KEGG, K01424 YP_001948475.1 COG1123: ATPase components of various ABC-type transporters, contain duplicated ATPase, Ralstonia solanacearum; KEGG, K02031 YP_001948476.1 COG0747: ABC-type dipeptide transporter, periplasmic component, Ralstonia solanacearum; KEGG, K02035 YP_001948477.1 COG0601: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Ralstonia solanacearum; KEGG, K02033 YP_001948478.1 COG1173: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Ralstonia solanacearum; KEGG, K02034 YP_001948479.1 COG3191: L-aminopeptidase/D-esterase, Ralstonia solanacearum; KEGG, K01266 YP_001948480.1 COG2362: D-aminopeptidase, Ralstonia solanacearum; KEGG, K02035 YP_001948481.1 COG3485: Protocatechuate 3,4-dioxygenase beta subunit, Caulobacter vibrioides; KEGG, K00448 YP_001948482.1 COG3485: Protocatechuate 3,4-dioxygenase beta subunit, Corynebacterium glutamicum; KEGG, K00449 YP_001948483.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; KEGG, K02623 YP_001948484.1 COG0531: Amino acid transporters, Bacillus subtilis; KEGG, K03294 YP_001948485.1 COG1201: Lhr-like helicases, Pseudomonas aeruginosa; KEGG, K03724; Lhr protein YP_001948487.1 COG0405: Gamma-glutamyltransferase, Caulobacter vibrioides; KEGG, K00681 YP_001948488.1 COG2326: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001948489.1 COG1739: Uncharacterized conserved protein, Ralstonia solanacearum YP_001948490.1 COG0546: phosphatases, Sinorhizobium meliloti; KEGG, K01091 YP_001948491.1 COG1472: Beta-glucosidase-related glycosidases, Caulobacter vibrioides; KEGG, K05349 YP_001948492.1 COG1596: Periplasmic protein involved in polysaccharide export, Ralstonia solanacearum; KEGG, K01991 YP_001948493.1 COG3206: Uncharacterized protein involved in exopolysaccharide biosynthesis, Ralstonia solanacearum; KEGG, K00903 YP_001948498.1 COG2244: Membrane protein involved in the export of O-antigen and teichoic acid, Methanothermobacter thermautotrophicus; KEGG, K03328 YP_001948499.1 COG0438: Glycosyltransferase, Sinorhizobium meliloti YP_001948502.1 COG0836: Mannose-1-phosphate guanylyltransferase, Yersinia pestis; KEGG, K00971 YP_001948504.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001948505.1 COG3250: Beta-galactosidase/beta-glucuronidase, Agrobacterium tumefaciens strain C58; KEGG, K01192 YP_001948507.1 COG0172: Seryl-tRNA synthetase, Agrobacterium tumefaciens strain C58 YP_001948508.1 COG1960: Acyl-CoA dehydrogenases, Agrobacterium tumefaciens strain C58; KEGG, K00249 YP_001948509.1 Involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides YP_001948510.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Synechocystis YP_001948511.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Synechocystis YP_001948512.1 COG2148: Sugar transferases involved in lipopolysaccharide synthesis, Escherichia coli K12; KEGG, K00996 YP_001948514.1 COG1796: DNA polymerase IV (family X), Methanothermobacter thermautotrophicus; KEGG, K02347 YP_001948515.1 COG0686: Alanine dehydrogenase, Vibrio cholerae; KEGG, K00259 YP_001948517.1 KEGG, K06152 YP_001948518.1 COG2303: Choline dehydrogenase and related flavoproteins, Pseudomonas aeruginosa; KEGG, K06151 YP_001948519.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa YP_001948520.1 COG4651: Kef-type K+ transporter, NAD-binding component, Mesorhizobium loti; KEGG, K03455 YP_001948521.1 COG0768: Cell division protein FtsI/penicillin-binding protein 2, Ralstonia solanacearum; FtsI protein; KEGG, K03587 YP_001948523.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum YP_001948524.1 COG1846: Transcriptional regulators, Ralstonia solanacearum YP_001948525.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Pseudomonas aeruginosa; KEGG, K01826 YP_001948526.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Pseudomonas aeruginosa; KEGG, K01614 YP_001948527.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00151 YP_001948528.1 COG3384: Uncharacterized conserved protein, Salmonella typhimurium LT2; KEGG, K00455 YP_001948529.1 COG3232: 5-carboxymethyl-2-hydroxymuconate isomerase, Ralstonia solanacearum; KEGG, K01826 YP_001948530.1 COG3971: 2-keto-4-pentenoate hydratase, Salmonella typhimurium LT2; KEGG, K02509 YP_001948531.1 COG3836: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, Salmonella typhimurium LT2; KEGG, K02510 YP_001948533.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001948535.1 KEGG, K00344 YP_001948536.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948537.1 COG3842: ABC-type spermidine/putrescine transporters, ATPase components, Ralstonia solanacearum; KEGG, K02010 YP_001948538.1 COG1178: ABC-type Fe3+ transporter, permease component, Ralstonia solanacearum; KEGG, K02011 YP_001948539.1 COG1840: ABC-type Fe3+ transporter, periplasmic component, Ralstonia solanacearum; KEGG, K02012 YP_001948540.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; CreB protein; KEGG, K07663 YP_001948541.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001948542.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum YP_001948543.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum YP_001948545.1 BaeS protein; COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07642 YP_001948546.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum YP_001948547.1 COG2207: AraC-type DNA-binding domain-containing proteins, Salmonella typhimurium LT2 YP_001948549.1 COG2303: Choline dehydrogenase and related flavoproteins, Pseudomonas aeruginosa YP_001948550.1 KEGG, K00368 YP_001948553.1 COG1033: exporters of the RND superfamily, Pseudomonas aeruginosa; KEGG, K07003 YP_001948554.1 COG4447: Uncharacterized protein related to plant photosystem II stability/assembly factor, Pseudomonas aeruginosa YP_001948555.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00154 YP_001948556.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum; KEGG, K07774; TctD protein YP_001948557.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K07649; TctE protein YP_001948558.1 COG3217: Uncharacterized Fe-S protein, Pseudomonas aeruginosa; KEGG, K07140; contains MOSC domain YP_001948559.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001948560.1 contains mono- or di-heme YP_001948561.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transporter, ATPase component, Agrobacterium tumefaciens strain C58; KEGG, K02049 YP_001948562.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transporter, permease component, Pseudomonas aeruginosa; KEGG, K02050 YP_001948563.1 KEGG, K02051 YP_001948564.1 COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases, Nostoc sp. PCC 7120 YP_001948565.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Pseudomonas aeruginosa; KEGG, K04091 YP_001948566.1 COG1960: Acyl-CoA dehydrogenases, Pseudomonas aeruginosa; KEGG, K00248 YP_001948567.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948568.1 COG5553: metal-dependent enzyme of the double-stranded beta helix superfamily, Pseudomonas aeruginosa YP_001948569.1 COG0607: Rhodanese-related sulfurtransferase, Pseudomonas aeruginosa YP_001948570.1 COG0584: Glycerophosphoryl diester phosphodiesterase, Ralstonia solanacearum; KEGG, K01126 YP_001948572.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948574.1 COG2128: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001948575.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00375; contains aminotransferase domain YP_001948576.1 COG0693: intracellular protease/amidase, Sinorhizobium meliloti YP_001948577.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Ralstonia solanacearum; KEGG, K00354 YP_001948578.1 COG0628: permease, Sinorhizobium meliloti YP_001948579.1 OsmE protein YP_001948580.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00059 YP_001948581.1 COG2207: AraC-type DNA-binding domain-containing proteins, Sinorhizobium meliloti YP_001948582.1 COG1280: threonine efflux protein, Pseudomonas aeruginosa YP_001948583.1 COG0642: Signal transduction histidine kinase, Pseudomonas aeruginosa; CusS protein; KEGG, K07644 YP_001948584.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Pseudomonas aeruginosa; CusR protein; KEGG, K07665 YP_001948585.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001948586.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum YP_001948587.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum YP_001948588.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Ralstonia solanacearum YP_001948589.1 activates fatty acids by binding to coenzyme A YP_001948590.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum YP_001948591.1 COG1238: membrane protein, Agrobacterium tumefaciens strain C58 YP_001948592.1 COG1280: threonine efflux protein, Sinorhizobium meliloti YP_001948593.1 COG1522: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001948595.1 COG1414: Transcriptional regulator, Ralstonia solanacearum YP_001948596.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Ralstonia solanacearum; KEGG, K01467 YP_001948597.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948598.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948599.1 COG0300: Short-chain dehydrogenases of various substrate specificities, Sinorhizobium meliloti; KEGG, K07124 YP_001948600.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Sinorhizobium meliloti YP_001948601.1 KEGG, K05913 YP_001948602.1 COG1846: Transcriptional regulators, Pseudomonas aeruginosa YP_001948603.1 COG0477: Permeases of the major facilitator superfamily, Clostridium acetobutylicum YP_001948604.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948605.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001948606.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00140 YP_001948607.1 COG4315: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001948608.1 COG0412: Dienelactone hydrolase and related enzymes, Mesorhizobium loti YP_001948609.1 COG2771: DNA-binding HTH domain-containing proteins, Pseudomonas aeruginosa YP_001948610.1 COG0531: Amino acid transporters, Pseudomonas aeruginosa YP_001948611.1 COG3191: L-aminopeptidase/D-esterase, Pseudomonas aeruginosa; KEGG, K01266 YP_001948613.1 COG1289: membrane protein, Pseudomonas aeruginosa YP_001948614.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948616.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948617.1 COG2764: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001948618.1 COG0402: Cytosine deaminase and related metal-dependent hydrolases, Salmonella typhimurium LT2; KEGG, K01485 YP_001948619.1 COG0038: Chloride channel protein EriC, Neisseria meningitidis MC58 YP_001948620.1 COG2031: Short chain fatty acids transporter, Escherichia coli K12; KEGG, K02106 YP_001948621.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001948622.1 COG3246: Uncharacterized conserved protein, Mesorhizobium loti YP_001948623.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti YP_001948624.1 COG1802: Transcriptional regulators, Mesorhizobium loti YP_001948625.1 involved in ubiquinone/menaquinone biosynthesis-like protein YP_001948626.1 COG1858: Cytochrome c peroxidase, Ralstonia solanacearum; KEGG, K00428 YP_001948627.1 COG3511: Phospholipase C, Ralstonia solanacearum; KEGG, K01114 YP_001948628.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Mesorhizobium loti YP_001948629.1 COG1522: Transcriptional regulators, Ralstonia solanacearum YP_001948630.1 COG1113: Gamma-aminobutyrate permease and related permeases, Yersinia pestis; KEGG, K03293 YP_001948631.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001948632.1 COG3189: Uncharacterized conserved protein, Ralstonia solanacearum YP_001948634.1 COG0664: cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases, Ralstonia solanacearum; KEGG, K01420 YP_001948636.1 catalyzes the formation of L-proline from L-ornithine YP_001948637.1 COG2186: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001948638.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum YP_001948639.1 COG3938: Proline racemase, Mesorhizobium loti; KEGG, K01777 YP_001948640.1 COG0744: Membrane carboxypeptidase (penicillin-binding protein), Helicobacter pylori J99; KEGG, K05364 YP_001948642.1 COG3755: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948643.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Ralstonia solanacearum; KEGG, K07689; UvrY protein YP_001948644.1 COG4585: Signal transduction histidine kinase, Ralstonia solanacearum YP_001948645.1 COG0589: Universal stress protein UspA and related nucleotide-binding proteins, Ralstonia solanacearum YP_001948646.1 COG3542: Uncharacterized conserved protein, Ralstonia solanacearum YP_001948647.1 COG0586: Uncharacterized membrane-associated protein, Ralstonia solanacearum YP_001948649.1 COG1113: Gamma-aminobutyrate permease and related permeases, Bacillus subtilis; KEGG, K03293 YP_001948652.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03406 YP_001948653.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001948654.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; contains a signal receiver domain YP_001948657.1 KEGG, K08995 YP_001948660.1 COG0517: FOG: CBS domain, Pseudomonas aeruginosa; contains CBS domains YP_001948664.1 COG3713: Outer membrane protein V, Mesorhizobium loti YP_001948666.1 COG1199: Rad3-related DNA helicases, Pseudomonas aeruginosa YP_001948667.1 COG1414: Transcriptional regulator, Sinorhizobium meliloti YP_001948668.1 COG3609: transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain, Sinorhizobium meliloti; KEGG, K07746 YP_001948670.1 COG0766: UDP-N-acetylglucosamine enolpyruvyl transferase, Borrelia burgdorferi; KEGG, K00790 YP_001948671.1 KEGG, K07451 YP_001948672.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli O157:H7; KEGG, K08172 YP_001948673.1 COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins, Ralstonia solanacearum; KEGG, K00457 YP_001948674.1 COG3550: Uncharacterized protein related to capsule biosynthesis enzymes, Ralstonia solanacearum; KEGG, K07154; related to capsule biosynthesis enzymes YP_001948678.1 COG1309: Transcriptional regulator, Pseudomonas aeruginosa YP_001948679.1 COG2130: NADP-dependent oxidoreductases, Pseudomonas aeruginosa; KEGG, K07119 YP_001948681.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Ralstonia solanacearum; KEGG, K07302 YP_001948682.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; KEGG, K00256 YP_001948683.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa YP_001948684.1 COG1012: NAD-dependent aldehyde dehydrogenases, Agrobacterium tumefaciens strain C58; KEGG, K00135 YP_001948685.1 COG1801: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001948687.1 COG4214: ABC-type xylose transporter, permease component, Ralstonia solanacearum; KEGG, K02057 YP_001948688.1 with XylFH is part of the high affinity xylose ABC transporter YP_001948689.1 COG4213: ABC-type xylose transporter, periplasmic component, Ralstonia solanacearum; KEGG, K02058 YP_001948690.1 COG1070: Sugar (pentulose and hexulose) kinases, Salmonella typhimurium LT2; KEGG, K00854 YP_001948691.1 catalyzes the interconversion of D-xylose to D-xylulose YP_001948692.1 COG1609: Transcriptional regulators, Yersinia pestis; KEGG, K02529 YP_001948693.1 COG2017: Galactose mutarotase and related enzymes, Caulobacter vibrioides; KEGG, K01785 YP_001948694.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948695.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum; KEGG, K03640 YP_001948697.1 COG2010: Cytochrome c, mono- and diheme variants, Pseudomonas aeruginosa YP_001948698.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Pseudomonas aeruginosa; KEGG, K04106 YP_001948699.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; KEGG, K00087 YP_001948700.1 COG2199: FOG: GGDEF domain, Caulobacter vibrioides; contains GGDEF domain YP_001948702.1 COG3608: deacylase, Agrobacterium tumefaciens strain C58; KEGG, K06987 YP_001948703.1 COG1396: transcriptional regulators, Xylella fastidiosa 9a5c YP_001948704.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Agrobacterium tumefaciens strain C58 YP_001948705.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Agrobacterium tumefaciens strain C58; KEGG, K02030 YP_001948706.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Agrobacterium tumefaciens strain C58 YP_001948707.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Agrobacterium tumefaciens strain C58; KEGG, K00492 YP_001948708.1 COG1126: ABC-type polar amino acid transporter, ATPase component, Agrobacterium tumefaciens strain C58; KEGG, K02028 YP_001948709.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Agrobacterium tumefaciens strain C58; KEGG, K02030 YP_001948711.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Pseudomonas aeruginosa; KEGG, K02014 YP_001948712.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K05874 YP_001948713.1 COG0380: Trehalose-6-phosphate synthase, Ralstonia solanacearum; KEGG, K00697 YP_001948715.1 COG0465: ATP-dependent Zn proteases, Nostoc sp. PCC 7120; FtsH protein; KEGG, K03798 YP_001948716.1 COG3511: Phospholipase C, Mesorhizobium loti; KEGG, K01114 YP_001948717.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001948718.1 COG2964: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001948719.1 catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine YP_001948721.1 COG0500: SAM-dependent methyltransferases, Mesorhizobium loti YP_001948723.1 COG4206: Outer membrane cobalamin receptor protein, Pseudomonas aeruginosa; KEGG, K02014 YP_001948727.1 COG5486: metal-binding integral membrane protein, Mesorhizobium loti YP_001948728.1 COG5588: Uncharacterized conserved protein, Mesorhizobium loti YP_001948729.1 COG0477: Permeases of the major facilitator superfamily, Xylella fastidiosa 9a5c YP_001948730.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001948731.1 COG1278: Cold shock proteins, Ralstonia solanacearum; KEGG, K03704 YP_001948733.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001948736.1 COG1409: phosphohydrolases, Mycobacterium tuberculosis CDC1551 YP_001948739.1 contains GGDEF domain YP_001948740.1 COG0687: Spermidine/putrescine-binding periplasmic protein, Mesorhizobium loti; KEGG, K02055 YP_001948741.1 COG2186: Transcriptional regulators, Caulobacter vibrioides YP_001948742.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_001948743.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08194 YP_001948744.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00811 YP_001948745.1 COG3946: Type IV secretory pathway, VirJ component, Agrobacterium tumefaciens strain C58 YP_001948746.1 COG2898: Uncharacterized conserved protein, Ralstonia solanacearum; KEGG, K07027 YP_001948747.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Pseudomonas aeruginosa; KEGG, K00491 YP_001948748.1 COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases, Ralstonia solanacearum; KEGG, K00363 YP_001948749.1 COG1251: NAD(P)H-nitrite reductase, Ralstonia solanacearum; KEGG, K00362 YP_001948750.1 COG2223: Nitrate/nitrite transporter, Ralstonia solanacearum; KEGG, K02575 YP_001948751.1 COG0007: Uroporphyrinogen-III methylase, Pseudomonas aeruginosa; KEGG, K02302 YP_001948752.1 COG3707: Response regulator with antiterminator output domain, Pseudomonas aeruginosa; KEGG, K07183; NasT protein YP_001948753.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001948754.1 COG1573: Uracil-DNA glycosylase, Vibrio cholerae YP_001948756.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Mesorhizobium loti; KEGG, K01557 YP_001948757.1 COG0477: Permeases of the major facilitator superfamily, Agrobacterium tumefaciens strain C58 YP_001948758.1 COG0265: Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain, Ralstonia solanacearum YP_001948759.1 COG0642: Signal transduction histidine kinase, Mesorhizobium loti; contains a signal receiver domain YP_001948760.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00375; contains aminotransferase domain YP_001948761.1 COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Saccharomyces cerevisiae YP_001948763.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001948764.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Pseudomonas aeruginosa; KEGG, K00008 YP_001948766.1 COG1266: metal-dependent membrane protease, Pseudomonas aeruginosa; KEGG, K07052 YP_001948767.1 COG0667: oxidoreductases (related to aryl-alcohol dehydrogenases), Salmonella typhimurium LT2; KEGG, K05882 YP_001948768.1 COG2095: Multiple antibiotic transporter, Caulobacter vibrioides; KEGG, K05595 YP_001948769.1 COG1024: Enoyl-CoA hydratase/carnithine racemase, Ralstonia solanacearum; KEGG, K01692 YP_001948770.1 COG1541: Coenzyme F390 synthetase, Ralstonia solanacearum; KEGG, K01912 YP_001948771.1 converts 3-hydroxyadipyl-CoA to beta-ketoadipyl-CoA in phenylacetate degradation YP_001948772.1 COG0387: Ca2+/H+ antiporter, Mycobacterium tuberculosis CDC1551; KEGG, K07300 YP_001948773.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948774.1 COG1052: Lactate dehydrogenase and related dehydrogenases, Sinorhizobium meliloti; KEGG, K00015 YP_001948775.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; KEGG, K08193 YP_001948776.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948777.1 COG3448: CBS-domain-containing membrane protein, Ralstonia solanacearum; KEGG, K07168 YP_001948778.1 COG1846: Transcriptional regulators, Ralstonia solanacearum YP_001948779.1 COG0038: Chloride channel protein EriC, Ralstonia solanacearum YP_001948780.1 COG3468: Type V secretory pathway, adhesin AidA, Brucella melitensis YP_001948781.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Ralstonia solanacearum; KEGG, K07302 YP_001948782.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Ralstonia solanacearum; CoxL protein YP_001948783.1 COG1305: Transglutaminase-like enzymes, cysteine proteases, Pseudomonas aeruginosa YP_001948784.1 COG2308: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001948785.1 COG4196: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001948786.1 COG1305: Transglutaminase-like enzymes, cysteine proteases, Agrobacterium tumefaciens strain C58 YP_001948787.1 COG2307: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001948789.1 COG2308: Uncharacterized conserved protein, Mesorhizobium loti YP_001948791.1 COG3123: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001948792.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948793.1 COG1473: Metal-dependent amidase/aminoacylase/carboxypeptidase, Pseudomonas aeruginosa; KEGG, K01451 YP_001948794.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001948798.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948799.1 COG2259: membrane protein, Ralstonia solanacearum YP_001948800.1 COG2010: Cytochrome c, mono- and diheme variants, Ralstonia solanacearum YP_001948801.1 COG2303: Choline dehydrogenase and related flavoproteins, Ralstonia solanacearum; KEGG, K08261 YP_001948803.1 COG2373: Large extracellular alpha-helical protein, Nostoc sp. PCC 7120; KEGG, K06894 YP_001948804.1 COG4953: Membrane carboxypeptidase/penicillin-binding protein PbpC, Nostoc sp. PCC 7120; KEGG, K05367 YP_001948806.1 COG0477: Permeases of the major facilitator superfamily, Salmonella typhimurium LT2; EmrD protein; KEGG, K08154 YP_001948808.1 COG3665: Uncharacterized conserved protein, Schizosaccharomyces pombe YP_001948809.1 COG1802: Transcriptional regulators, Agrobacterium tumefaciens strain C58 YP_001948810.1 N-acetyldiaminobutyrate dehydratase; catalyzes the formation of the osmoprotectant ecotoine from gamma-N-acetyl-alpha,gamma-diaminobutyric acid YP_001948811.1 COG0154: Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases, Sinorhizobium meliloti; KEGG, K01426 YP_001948812.1 COG1126: ABC-type polar amino acid transporter, ATPase component, Ralstonia solanacearum YP_001948813.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Agrobacterium tumefaciens strain C58 YP_001948814.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Ralstonia solanacearum; KEGG, K02030 YP_001948815.1 COG1404: Subtilisin-like serine proteases, Ralstonia solanacearum; KEGG, K01362 YP_001948816.1 COG0474: Cation transport ATPase, Pseudomonas aeruginosa; KEGG, K01531 YP_001948819.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948821.1 COG1686: D-alanyl-D-alanine carboxypeptidase, Ralstonia solanacearum; KEGG, K01286 YP_001948824.1 COG1335: Amidases related to nicotinamidase, Bacillus subtilis; KEGG, K05993 YP_001948825.1 COG0477: Permeases of the major facilitator superfamily, Mycobacterium tuberculosis H37Rv YP_001948826.1 COG1280: threonine efflux protein, Mesorhizobium loti YP_001948827.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001948828.1 COG0668: Small-conductance mechanosensitive channel, Pseudomonas aeruginosa YP_001948829.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00825 YP_001948830.1 COG0243: Anaerobic dehydrogenases, typically selenocysteine-containing, Ralstonia solanacearum; KEGG, K00122 YP_001948831.1 COG3781: membrane protein, Ralstonia solanacearum; KEGG, K08994 YP_001948834.1 COG0747: ABC-type dipeptide transporter, periplasmic component, Sinorhizobium meliloti; KEGG, K02035 YP_001948836.1 catalyzes the hydrolysis of D-alanyl-D-alanine dipeptide: Zn dependent; involved in peptidoglycan synthesis YP_001948838.1 COG0601: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Agrobacterium tumefaciens strain C58; KEGG, K02033 YP_001948839.1 COG1173: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Sinorhizobium meliloti; KEGG, K02034 YP_001948840.1 COG0444: ABC-type dipeptide/oligopeptide/nickel transporter, ATPase component, Sinorhizobium meliloti; KEGG, K02031 YP_001948841.1 COG1124: ABC-type dipeptide/oligopeptide/nickel transporter, ATPase component, Sinorhizobium meliloti; KEGG, K02032 YP_001948842.1 COG2261: membrane protein, Pseudomonas aeruginosa YP_001948844.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa; KEGG, K03566 YP_001948845.1 COG2367: Beta-lactamase class A, Sinorhizobium meliloti; KEGG, K01467 YP_001948846.1 KEGG, K06194; NlpD protein YP_001948848.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948849.1 COG5485: ester cyclase, Mesorhizobium loti YP_001948851.1 COG0730: permeases, Mesorhizobium loti; KEGG, K07090 YP_001948852.1 COG0667: oxidoreductases (related to aryl-alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K05275 YP_001948853.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948854.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948855.1 COG4645: Uncharacterized protein conserved in bacteria, Brucella melitensis YP_001948856.1 COG0627: esterase, Agrobacterium tumefaciens strain C58 YP_001948857.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02051 YP_001948858.1 COG0600: ABC-type nitrate/sulfonate/bicarbonate transporter, permease component, Pseudomonas aeruginosa; KEGG, K02050 YP_001948859.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transporter, ATPase component, Pseudomonas aeruginosa; KEGG, K02049 YP_001948860.1 COG0654: 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases, Agrobacterium tumefaciens strain C58; KEGG, K00480 YP_001948861.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001948862.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti; KEGG, K00059 YP_001948863.1 COG1226: Kef-type K+ transporters, NAD-binding component, Mycobacterium tuberculosis CDC1551 YP_001948866.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03406 YP_001948868.1 COG1247: Sortase and related acyltransferases, Caulobacter vibrioides; KEGG, K03823 YP_001948870.1 COG0715: ABC-type nitrate/sulfonate/bicarbonate transporters, periplasmic components, Ralstonia solanacearum; KEGG, K02051 YP_001948871.1 COG3714: membrane protein, Mycobacterium tuberculosis CDC1551 YP_001948872.1 COG2072: flavoprotein involved in K+ transport, Pseudomonas aeruginosa; KEGG, K03379 YP_001948873.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00044 YP_001948874.1 COG3687: metal-dependent hydrolase, Pseudomonas aeruginosa; KEGG, K07044 YP_001948875.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa; KEGG, K01561 YP_001948876.1 COG3554: Uncharacterized protein conserved in bacteria, Sinorhizobium meliloti YP_001948877.1 COG4413: Urea transporter, Pseudomonas aeruginosa; KEGG, K08717 YP_001948878.1 COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases, Ralstonia solanacearum YP_001948879.1 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown YP_001948881.1 COG2902: NAD-specific glutamate dehydrogenase, Pseudomonas aeruginosa YP_001948882.1 COG3315: O-Methyltransferase involved in polyketide biosynthesis, Mesorhizobium loti; involved in polyketide biosynthesis YP_001948885.1 COG2162: Arylamine N-acetyltransferase, Mesorhizobium loti; KEGG, K00675 YP_001948887.1 COG3659: Carbohydrate-selective porin, Ralstonia solanacearum; KEGG, K07267 YP_001948888.1 catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia YP_001948891.1 COG1914: Mn2+ and Fe2+ transporters of the NRAMP family, Sinorhizobium meliloti YP_001948892.1 COG4320: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001948893.1 COG1661: DNA-binding protein with PD1-like DNA-binding motif, Escherichia coli O157:H7; KEGG, K06934; contains PD1-like DNA-binding motif YP_001948894.1 COG0477: Permeases of the major facilitator superfamily, Agrobacterium tumefaciens strain C58 YP_001948895.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Mesorhizobium loti; KEGG, K00529 YP_001948896.1 COG0346: Lactoylglutathione lyase and related lyases, Pseudomonas aeruginosa; KEGG, K00446 YP_001948897.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00130 YP_001948898.1 catalyzes the formation of L-aspartate to iminoaspartate in NAD(+) biosynthesis YP_001948899.1 COG0028: Thiamine pyrophosphate-requiring enzymes; KEGG, K01651 YP_001948900.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00059 YP_001948901.1 COG1414: Transcriptional regulator, Pseudomonas aeruginosa YP_001948902.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa YP_001948904.1 member of a large family of NAD or NADP-dependent oxidoreductases; paralogs occur in many bacteria YP_001948905.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Pseudomonas aeruginosa; KEGG, K03461 YP_001948907.1 COG2146: Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases, Yersinia pestis; KEGG, K05710 YP_001948908.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948909.1 COG1414: Transcriptional regulator, Pseudomonas aeruginosa YP_001948911.1 COG3145: Alkylated DNA repair protein, Pseudomonas aeruginosa YP_001948912.1 KEGG, K07098 YP_001948914.1 with MdtO and MdtP is involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride YP_001948915.1 COG1289: membrane protein, Yersinia pestis YP_001948916.1 COG1538: Outer membrane protein, Yersinia pestis YP_001948917.1 COG1285: Uncharacterized membrane protein, Pseudomonas aeruginosa; KEGG, K07507 YP_001948918.1 COG2771: DNA-binding HTH domain-containing proteins, Ralstonia solanacearum; KEGG, K07782 YP_001948920.1 COG3916: N-acyl-L-homoserine lactone synthetase, Ralstonia solanacearum YP_001948922.1 COG1473: Metal-dependent amidase/aminoacylase/carboxypeptidase, Mesorhizobium loti; KEGG, K01451 YP_001948923.1 COG1522: Transcriptional regulators, Mesorhizobium loti YP_001948924.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_001948925.1 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide YP_001948927.1 COG3220: Uncharacterized protein conserved in bacteria, Caulobacter vibrioides YP_001948929.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Escherichia coli O157:H7 YP_001948931.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001948932.1 COG0702: nucleoside-diphosphate-sugar epimerases, Mesorhizobium loti YP_001948933.1 COG1182: Acyl carrier protein phosphodiesterase, Ralstonia solanacearum; KEGG, K01118 YP_001948934.1 COG0625: Glutathione S-transferase, Caulobacter vibrioides; KEGG, K00799 YP_001948935.1 COG2128: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001948936.1 COG0778: Nitroreductase, Halobacterium sp. NRC-1; KEGG, K00540 YP_001948937.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001948938.1 COG1917: Uncharacterized conserved protein, contains double-stranded beta-helix domain, Agrobacterium tumefaciens strain C58 YP_001948939.1 Catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001948940.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Sinorhizobium meliloti YP_001948943.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Escherichia coli O157:H7; KEGG, K00375; contains aminotransferase domain YP_001948944.1 COG0807: GTP cyclohydrolase II, Chlamydia trachomatis; KEGG, K01497 YP_001948945.1 COG0517: FOG: CBS domain, Pseudomonas aeruginosa; contains CBS domains YP_001948947.1 COG0782: Transcription elongation factor, Ralstonia solanacearum; KEGG, K06140 YP_001948948.1 OrfA YP_001948949.1 OrfB YP_001948950.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001948952.1 COG1335: Amidases related to nicotinamidase, Bacillus subtilis YP_001948953.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K03762 YP_001948954.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948955.1 COG1457: Purine-cytosine permease and related proteins, Pseudomonas aeruginosa YP_001948956.1 COG1538: Outer membrane protein, Pseudomonas aeruginosa YP_001948957.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum YP_001948958.1 COG0845: Membrane-fusion protein, Pseudomonas aeruginosa YP_001948959.1 COG0789: transcriptional regulators, Mesorhizobium loti YP_001948960.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa; KEGG, K00059 YP_001948961.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001948963.1 COG1252: NADH dehydrogenase, FAD-containing subunit, Salmonella typhimurium LT2; KEGG, K03885 YP_001948966.1 COG3523: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948967.1 COG3455: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948975.1 COG3522: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948976.1 OrfA YP_001948977.1 OrfB YP_001948978.1 COG3521: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948979.1 COG3157: Hemolysin-coregulated protein (uncharacterized), Salmonella typhimurium LT2; KEGG, K06887 YP_001948980.1 COG3517: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948981.1 COG3516: Uncharacterized protein conserved in bacteria, Yersinia pestis YP_001948982.1 COG0542: ATPases with chaperone activity, ATP-binding subunit, Salmonella typhimurium LT2 YP_001948984.1 COG3518: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948985.1 COG3519: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948986.1 COG3520: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948987.1 COG3515: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001948988.1 COG1116: ABC-type nitrate/sulfonate/bicarbonate transporter, ATPase component, Xylella fastidiosa 9a5c; KEGG, K02049 YP_001948989.1 COG4986: ABC-type anion transporter, duplicated permease component, Xylella fastidiosa 9a5c; KEGG, K02050 YP_001948990.1 COG1409: phosphohydrolases, Ralstonia solanacearum YP_001948992.1 COG1752: esterase of the alpha-beta hydrolase superfamily, Mesorhizobium loti YP_001948993.1 COG0583: Transcriptional regulator, Brucella melitensis YP_001948994.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08224 YP_001948995.1 COG0640: transcriptional regulators, Pseudomonas aeruginosa; KEGG, K03892 YP_001948996.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Pseudomonas aeruginosa; KEGG, K00354 YP_001948997.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Caulobacter vibrioides YP_001948998.1 COG1961: Site-specific recombinases, DNA invertase Pin homologs, Mesorhizobium loti YP_001949002.1 KEGG, K01185 YP_001949006.1 COG4733: Phage-related protein, tail component, Ralstonia solanacearum YP_001949007.1 COG4723: Phage-related protein, tail component, Ralstonia solanacearum YP_001949008.1 COG0791: Cell wall-associated hydrolases (invasion-associated proteins), Ralstonia solanacearum YP_001949009.1 COG4672: Phage-related protein, Ralstonia solanacearum YP_001949012.1 COG5281: Phage-related minor tail protein, Ralstonia solanacearum YP_001949021.1 COG4653: phage phi-C31 gp36 major capsid-like protein, Agrobacterium tumefaciens strain C58 YP_001949022.1 COG0740: Protease subunit of ATP-dependent Clp proteases, Mesorhizobium loti; KEGG, K01358 YP_001949023.1 COG4695: Phage-related protein, Mesorhizobium loti YP_001949024.1 COG4626: Phage terminase-like protein, large subunit, Escherichia coli O157:H7 EDL933 YP_001949077.1 COG2391: transporter component, Pseudomonas aeruginosa; KEGG, K07112 YP_001949078.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001949079.1 COG2207: AraC-type DNA-binding domain-containing proteins, Escherichia coli K12 YP_001949081.1 COG0531: Amino acid transporters, Pseudomonas aeruginosa YP_001949082.1 COG0161: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase, Brucella melitensis; KEGG, K00833 YP_001949083.1 COG2771: DNA-binding HTH domain-containing proteins, Pseudomonas aeruginosa YP_001949084.1 COG2321: metalloprotease, Pseudomonas aeruginosa; KEGG, K07054 YP_001949085.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Mesorhizobium loti; KEGG, K00059 YP_001949086.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949088.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli O157:H7 YP_001949090.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Ralstonia solanacearum YP_001949091.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001949092.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001949093.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001949095.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001949096.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Halobacterium sp. NRC-1; KEGG, K00059 YP_001949097.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001949099.1 COG2207: AraC-type DNA-binding domain-containing proteins, Sinorhizobium meliloti YP_001949100.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Sinorhizobium meliloti YP_001949103.1 catalyzes the conversion of carbamoyl phosphate and aspartate to form N-carbamoyl aspartate YP_001949104.1 COG1487: nucleic acid-binding protein, contains PIN domain, Xylella fastidiosa 9a5c; KEGG, K07062 YP_001949106.1 COG4774: Outer membrane receptor for monomeric catechols, Pseudomonas aeruginosa; KEGG, K02014 YP_001949107.1 COG0790: FOG: TPR repeat, SEL1 subfamily, Pseudomonas aeruginosa; KEGG, K07126; contains TRP repeat YP_001949108.1 COG3128: Uncharacterized iron-regulated protein, Pseudomonas aeruginosa; KEGG, K00478 YP_001949110.1 COG3744: Uncharacterized protein conserved in bacteria, Nostoc sp. PCC 7120 YP_001949111.1 COG2068: Uncharacterized MobA-related protein, Ralstonia solanacearum; KEGG, K07141 YP_001949113.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Agrobacterium tumefaciens strain C58; KEGG, K00079 YP_001949114.1 COG1070: Sugar (pentulose and hexulose) kinases, Thermotoga maritima; KEGG, K00851 YP_001949115.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Yersinia pestis; KEGG, K00008 YP_001949116.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transporters, permease components, Agrobacterium tumefaciens strain C58; KEGG, K02057 YP_001949117.1 COG1129: ABC-type sugar transporter, ATPase component, Agrobacterium tumefaciens strain C58; KEGG, K02056 YP_001949118.1 COG1879: ABC-type sugar transporter, periplasmic component, Agrobacterium tumefaciens strain C58; KEGG, K02058 YP_001949119.1 COG2207: AraC-type DNA-binding domain-containing proteins, Agrobacterium tumefaciens strain C58 YP_001949120.1 COG1893: Ketopantoate reductase, Ralstonia solanacearum; KEGG, K00077 YP_001949121.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03406 YP_001949122.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Pseudomonas aeruginosa YP_001949124.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum YP_001949130.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Sinorhizobium meliloti; KEGG, K01710 YP_001949131.1 COG1087: UDP-glucose 4-epimerase, Sinorhizobium meliloti; KEGG, K01784 YP_001949132.1 COG1004: UDP-glucose 6-dehydrogenase, Sinorhizobium meliloti; KEGG, K00012 YP_001949133.1 COG1215: Glycosyltransferases, probably involved in cell wall biogenesis, Sinorhizobium meliloti; KEGG, K00694 YP_001949136.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa YP_001949137.1 Converts (S)-3-hydroxyactk-CoA to 3-oxoayl-CoA YP_001949138.1 COG2031: Short chain fatty acids transporter, Bacillus halodurans YP_001949139.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the reactions based on sequence and structure similarity YP_001949140.1 COG2207: AraC-type DNA-binding domain-containing proteins, Sinorhizobium meliloti YP_001949141.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Pseudomonas aeruginosa; KEGG, K07302 YP_001949142.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; KEGG, K07303 YP_001949145.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_001949146.1 KEGG, K03194; VirB1 protein YP_001949148.1 COG0367: Asparagine synthase (glutamine-hydrolyzing), Mesorhizobium loti; KEGG, K01953 YP_001949149.1 COG4792: Type III secretory pathway, component EscU, Yersinia pestis; FlhB protein YP_001949150.1 COG4791: Type III secretory pathway, component EscT, Ralstonia solanacearum; KEGG, K03228 YP_001949152.1 COG1157: Flagellar biosynthesis/type III secretory pathway ATPase, Pseudomonas aeruginosa; KEGG, K03224 YP_001949153.1 COG1317: Flagellar biosynthesis/type III secretory pathway protein, Yersinia pestis YP_001949155.1 COG4669: Type III secretory pathway, lipoprotein EscJ, Ralstonia solanacearum; KEGG, K03222 YP_001949159.1 COG1450: Type II secretory pathway, component PulD, Ralstonia solanacearum YP_001949161.1 COG4789: Type III secretory pathway, component EscV, Ralstonia solanacearum; KEGG, K03230 YP_001949164.1 COG1914: Mn2+ and Fe2+ transporters of the NRAMP family, Ralstonia solanacearum YP_001949167.1 COG1626: Neutral trehalase, Ralstonia solanacearum; KEGG, K01194 YP_001949168.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001949169.1 COG3214: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001949171.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum YP_001949172.1 COG0546: phosphatases, Ralstonia solanacearum; KEGG, K01091 YP_001949174.1 COG1670: Acetyltransferases, including N-acetylases of ribosomal proteins, Ralstonia solanacearum YP_001949175.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_001949176.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_001949177.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Agrobacterium tumefaciens strain C58 YP_001949178.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Mesorhizobium loti YP_001949180.1 COG0174: Glutamine synthetase, Pseudomonas aeruginosa; KEGG, K01915 YP_001949181.1 COG1396: transcriptional regulators, Pseudomonas aeruginosa YP_001949182.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Pseudomonas aeruginosa; KEGG, K09471 YP_001949184.1 COG0642: Signal transduction histidine kinase, Pseudomonas aeruginosa YP_001949185.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Vibrio cholerae; KEGG, K07685; NarP protein YP_001949188.1 COG5483: Uncharacterized conserved protein, Aeropyrum pernix YP_001949189.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum; KEGG, K02022 YP_001949190.1 COG2274: ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain, Ralstonia solanacearum; KEGG, K06148 YP_001949191.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001949192.1 AdhA protein; COG3210: Large exoproteins involved in heme utilization or adhesion, Ralstonia solanacearum YP_001949193.1 COG0730: permeases, Ralstonia solanacearum; KEGG, K07090 YP_001949194.1 COG4094: membrane protein, Sinorhizobium meliloti YP_001949196.1 COG2055: Malate/L-lactate dehydrogenases, Escherichia coli O157:H7; KEGG, K00025 YP_001949197.1 COG0624: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases, Mycobacterium tuberculosis CDC1551 YP_001949198.1 COG0531: Amino acid transporters, Salmonella typhimurium LT2; KEGG, K03759 YP_001949199.1 COG1982: Arginine/lysine/ornithine decarboxylases, Salmonella typhimurium LT2; KEGG, K01582 YP_001949201.1 upregulated by FixLJ/FixK under oxygen limitation; involved in regulation of genes involved in carbon and amino acid metabolism YP_001949202.1 COG0607: Rhodanese-related sulfurtransferase, Vibrio cholerae YP_001949204.1 KEGG, K00493 YP_001949206.1 COG2513: PEP phosphonomutase and related enzymes, Ralstonia solanacearum YP_001949207.1 COG1737: Transcriptional regulators, Mesorhizobium loti YP_001949209.1 BasR protein; COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Pseudomonas aeruginosa; KEGG, K07771 YP_001949210.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K00936 YP_001949211.1 COG2367: Beta-lactamase class A, Mycobacterium tuberculosis CDC1551; KEGG, K01467 YP_001949212.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa; PenR protein YP_001949214.1 COG3408: Glycogen debranching enzyme, Mesorhizobium loti YP_001949215.1 COG1077: Actin-like ATPase involved in cell morphogenesis, Ralstonia solanacearum; KEGG, K03569; MreB protein YP_001949216.1 COG1752: esterase of the alpha-beta hydrolase superfamily, Pseudomonas aeruginosa; KEGG, K07001 YP_001949217.1 COG4566: Response regulator, Ralstonia solanacearum YP_001949218.1 KEGG, K00936 YP_001949219.1 COG1638: TRAP-type C4-dicarboxylate transporter, periplasmic component, Pseudomonas aeruginosa YP_001949221.1 COG1593: TRAP-type C4-dicarboxylate transporter, large permease component, Pseudomonas aeruginosa; DctM protein YP_001949222.1 KEGG, K07639; RstB protein YP_001949223.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Pseudomonas aeruginosa; KEGG, K07661 YP_001949224.1 catalyzes the formation of glutamate from glutamine YP_001949226.1 COG0494: NTP pyrophosphohydrolases including oxidative damage repair enzymes, Caulobacter vibrioides; KEGG, K01515 YP_001949227.1 COG1349: Transcriptional regulators of sugar metabolism, Sinorhizobium meliloti; KEGG, K03436 YP_001949228.1 COG3268: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001949229.1 COG1073: Hydrolases of the alpha/beta superfamily, Archaeoglobus fulgidus; KEGG, K06889 YP_001949230.1 COG2072: flavoprotein involved in K+ transport, Mycobacterium tuberculosis CDC1551; involved in K+ transport YP_001949231.1 COG2207: AraC-type DNA-binding domain-containing proteins, Mycobacterium tuberculosis CDC1551 YP_001949232.1 COG1335: Amidases related to nicotinamidase, Ralstonia solanacearum YP_001949233.1 COG3719: Ribonuclease I, Sinorhizobium meliloti; KEGG, K01169 YP_001949235.1 COG1396: transcriptional regulators, Pseudomonas aeruginosa YP_001949236.1 COG1896: hydrolases of HD superfamily, Pseudomonas aeruginosa; KEGG, K07023 YP_001949237.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08170 YP_001949238.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001949239.1 COG1024: Enoyl-CoA hydratase/carnithine racemase, Ralstonia solanacearum; KEGG, K01692 YP_001949240.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001949241.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Ralstonia solanacearum; KEGG, K00020 YP_001949242.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00140 YP_001949243.1 COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases, Ralstonia solanacearum; KEGG, K01895 YP_001949244.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00257 YP_001949245.1 COG2207: AraC-type DNA-binding domain-containing proteins, Ralstonia solanacearum YP_001949246.1 COG1030: Membrane-bound serine protease (ClpP class), Ralstonia solanacearum; KEGG, K07403 YP_001949247.1 COG0330: Membrane protease subunits, stomatin/prohibitin homologs, Ralstonia solanacearum YP_001949248.1 COG4823: Abortive infection bacteriophage resistance protein, Pasteurella multocida YP_001949250.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa; KEGG, K00079 YP_001949251.1 COG3687: metal-dependent hydrolase, Pseudomonas aeruginosa; KEGG, K07044 YP_001949255.1 COG2252: Permeases, Ralstonia solanacearum; KEGG, K06901 YP_001949258.1 COG3284: Transcriptional activator of acetoin/glycerol metabolism, Pseudomonas aeruginosa YP_001949259.1 KEGG, K00529 YP_001949261.1 COG4886: Leucine-rich repeat (LRR) protein, Pseudomonas aeruginosa YP_001949264.1 COG0382: 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases, Ralstonia solanacearum; KEGG, K00810 YP_001949265.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001949266.1 COG4954: Uncharacterized protein conserved in bacteria, Agrobacterium tumefaciens strain C58 YP_001949267.1 COG0346: Lactoylglutathione lyase and related lyases, Mesorhizobium loti YP_001949268.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Mesorhizobium loti YP_001949271.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949272.1 COG0410: ABC-type branched-chain amino acid transporters, ATPase component, Salmonella typhimurium LT2; KEGG, K01996 YP_001949273.1 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001949274.1 Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine YP_001949275.1 COG0559: Branched-chain amino acid ABC-type transporter, permease components, Pseudomonas aeruginosa; KEGG, K01997 YP_001949276.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Pseudomonas aeruginosa; KEGG, K01999 YP_001949278.1 COG0075: Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase, Deinococcus radiodurans; KEGG, K00828 YP_001949281.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Yersinia pestis YP_001949282.1 COG2199: FOG: GGDEF domain, Yersinia pestis; contains GGDEF domain YP_001949284.1 COG1529: Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs, Pseudomonas aeruginosa; KEGG, K07303 YP_001949285.1 COG2080: Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs, Caulobacter vibrioides; KEGG, K00256 YP_001949286.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001949287.1 COG0583: Transcriptional regulator, Sinorhizobium meliloti YP_001949288.1 COG2159: metal-dependent hydrolase of the TIM-barrel fold, Sinorhizobium meliloti; KEGG, K07045 YP_001949289.1 COG2159: metal-dependent hydrolase of the TIM-barrel fold, Sinorhizobium meliloti; KEGG, K07045 YP_001949290.1 COG0043: 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases, Sinorhizobium meliloti YP_001949291.1 COG0163: 3-polyprenyl-4-hydroxybenzoate decarboxylase, Sinorhizobium meliloti; KEGG, K03186; UbiX protein YP_001949292.1 COG0523: GTPases (G3E family), Sinorhizobium meliloti YP_001949293.1 COG2233: Xanthine/uracil permeases, Ralstonia solanacearum YP_001949294.1 COG0402: Cytosine deaminase and related metal-dependent hydrolases, Pseudomonas aeruginosa; KEGG, K03382 YP_001949295.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti; KEGG, K00285 YP_001949296.1 COG2186: Transcriptional regulators, Caulobacter vibrioides YP_001949297.1 COG3618: metal-dependent hydrolase of the TIM-barrel fold, Agrobacterium tumefaciens strain C58; KEGG, K07046 YP_001949298.1 COG1879: ABC-type sugar transporter, periplasmic component, Sinorhizobium meliloti; KEGG, K02058 YP_001949299.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transporters, permease components, Vibrio cholerae; KEGG, K02057 YP_001949300.1 COG1129: ABC-type sugar transporter, ATPase component, Agrobacterium tumefaciens strain C58; KEGG, K02056 YP_001949301.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Campylobacter jejuni; KEGG, K00059 YP_001949302.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Brucella melitensis; KEGG, K01781 YP_001949303.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Yersinia pestis; KEGG, K01828 YP_001949304.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Yersinia pestis; KEGG, K00540 YP_001949307.1 COG0657: Esterase/lipase, Mesorhizobium loti YP_001949308.1 COG0824: thioesterase, Pseudomonas aeruginosa; KEGG, K07107 YP_001949309.1 converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA YP_001949310.1 COG3246: Uncharacterized conserved protein, Pseudomonas aeruginosa YP_001949311.1 COG2113: ABC-type proline/glycine betaine transporters, periplasmic components, Pseudomonas aeruginosa; KEGG, K02002 YP_001949312.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001949313.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00128 YP_001949316.1 KEGG, K08685 YP_001949319.1 KEGG, K08685 YP_001949320.1 COG2207: AraC-type DNA-binding domain-containing proteins, Salmonella typhimurium LT2 YP_001949321.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Pseudomonas aeruginosa YP_001949323.1 COG3295: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001949324.1 COG3128: Uncharacterized iron-regulated protein, Pseudomonas aeruginosa YP_001949325.1 COG4774: Outer membrane receptor for monomeric catechols, Pseudomonas aeruginosa YP_001949326.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001949327.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum; KEGG, K08720; OmpU protein YP_001949328.1 COG2113: ABC-type proline/glycine betaine transporters, periplasmic components, Agrobacterium tumefaciens strain C58; KEGG, K02002 YP_001949329.1 COG3119: Arylsulfatase A and related enzymes, Pseudomonas aeruginosa; KEGG, K01133 YP_001949330.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949332.1 KEGG, K01992 YP_001949333.1 KEGG, K01990 YP_001949334.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001949335.1 COG1072: Panthothenate kinase, Sinorhizobium meliloti; KEGG, K00867 YP_001949336.1 COG1082: Sugar phosphate isomerases/epimerases, Mesorhizobium loti YP_001949337.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transporters, permease components, Sinorhizobium meliloti; KEGG, K02057 YP_001949338.1 COG1172: Ribose/xylose/arabinose/galactoside ABC-type transporters, permease components, Agrobacterium tumefaciens strain C58; KEGG, K02057 YP_001949339.1 COG1129: ABC-type sugar transporter, ATPase component, Sinorhizobium meliloti; KEGG, K02056 YP_001949340.1 COG1879: ABC-type sugar transporter, periplasmic component, Agrobacterium tumefaciens strain C58; KEGG, K02058 YP_001949341.1 COG1609: Transcriptional regulators, Agrobacterium tumefaciens strain C58; KEGG, K03435 YP_001949342.1 COG0531: Amino acid transporters, Mesorhizobium loti YP_001949343.1 COG2113: ABC-type proline/glycine betaine transporters, periplasmic components, Ralstonia solanacearum; KEGG, K02002 YP_001949345.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Ralstonia solanacearum; KEGG, K00529 YP_001949346.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Ralstonia solanacearum YP_001949347.1 COG2086: Electron transfer flavoprotein, beta subunit, Ralstonia solanacearum; KEGG, K03521 YP_001949348.1 COG2025: Electron transfer flavoprotein, alpha subunit, Ralstonia solanacearum; KEGG, K03522 YP_001949349.1 COG0247: Fe-S oxidoreductase, Ralstonia solanacearum; KEGG, K08263 YP_001949350.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Ralstonia solanacearum; KEGG, K00219 YP_001949352.1 COG2355: Zn-dependent dipeptidase, microsomal dipeptidase homolog, Ralstonia solanacearum; KEGG, K01273 YP_001949353.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001949354.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Ralstonia solanacearum YP_001949355.1 COG0823: Periplasmic component of the Tol biopolymer transporter, Ralstonia solanacearum YP_001949356.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00811 YP_001949358.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Ralstonia solanacearum YP_001949359.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949360.1 COG1063: Threonine dehydrogenase and related Zn-dependent dehydrogenases, Ralstonia solanacearum; KEGG, K00148 YP_001949361.1 HTH-type; bet1; Repressor involved in choline regulation of the bet genes YP_001949362.1 catalyzes the formation of betaine from betaine aldehyde YP_001949363.1 catalyzes the oxidation of choline to betaine aldehyde and betain aldehyde to glycine betaine YP_001949364.1 COG1131: ABC-type multidrug transporter, ATPase component, Caulobacter vibrioides; KEGG, K01990 YP_001949365.1 COG0842: ABC-type multidrug transporter, permease component, Mesorhizobium loti; KEGG, K01992 YP_001949366.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K08369 YP_001949368.1 COG3795: Uncharacterized protein conserved in bacteria, Pseudomonas aeruginosa YP_001949369.1 COG0627: esterase, Pasteurella multocida YP_001949370.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Pseudomonas aeruginosa YP_001949371.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001949372.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis YP_001949373.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58 YP_001949374.1 COG2885: Outer membrane protein and related peptidoglycan-associated (lipo)proteins, Ralstonia solanacearum YP_001949376.1 COG0642: Signal transduction histidine kinase, Ralstonia solanacearum; contains an extracellular sensory domain YP_001949377.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Ralstonia solanacearum YP_001949381.1 COG1020: Non-ribosomal peptide synthetase modules and related proteins, Pseudomonas aeruginosa YP_001949382.1 COG1764: redox protein, regulator of disulfide bond formation, Vibrio cholerae YP_001949383.1 COG1052: Lactate dehydrogenase and related dehydrogenases, Ralstonia solanacearum; KEGG, K00058 YP_001949384.1 COG1732: Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transporter (osmoprotectant binding protein), Mesorhizobium loti; KEGG, K05845 YP_001949385.1 COG1174: ABC-type proline/glycine betaine transporters, permease component, Mesorhizobium loti; KEGG, K05846 YP_001949386.1 COG1125: ABC-type proline/glycine betaine transporters, ATPase components, Mesorhizobium loti; KEGG, K05847 YP_001949387.1 COG1174: ABC-type proline/glycine betaine transporters, permease component, Mesorhizobium loti; KEGG, K05846 YP_001949389.1 COG1539: Dihydroneopterin aldolase, Ralstonia solanacearum; KEGG, K01633 YP_001949390.1 COG4583: Sarcosine oxidase gamma subunit, Ralstonia solanacearum; KEGG, K00305 YP_001949391.1 COG0446: Uncharacterized NAD(FAD)-dependent dehydrogenases, Ralstonia solanacearum; KEGG, K00302 YP_001949392.1 COG4311: Sarcosine oxidase delta subunit, Ralstonia solanacearum; KEGG, K00304 YP_001949393.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Ralstonia solanacearum; KEGG, K00303 YP_001949394.1 COG1760: L-serine deaminase, Ralstonia solanacearum; KEGG, K01752 YP_001949395.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Ralstonia solanacearum YP_001949396.1 COG2186: Transcriptional regulators, Sinorhizobium meliloti YP_001949397.1 COG2084: 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases, Salmonella typhimurium LT2; KEGG, K00020 YP_001949398.1 COG3395: Uncharacterized protein conserved in bacteria, Pasteurella multocida; conserved in bacteria YP_001949399.1 COG0235: Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases, Sinorhizobium meliloti; KEGG, K01628 YP_001949400.1 COG0477: Permeases of the major facilitator superfamily, Brucella melitensis YP_001949401.1 COG3622: Hydroxypyruvate isomerase, Ralstonia solanacearum; KEGG, K01816 YP_001949402.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Yersinia pestis; KEGG, K01784 YP_001949405.1 COG3555: Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases, Mesorhizobium loti; KEGG, K00476 YP_001949409.1 COG2113: ABC-type proline/glycine betaine transporters, periplasmic components, Brucella melitensis; KEGG, K02002 YP_001949410.1 COG4977: Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, Ralstonia solanacearum YP_001949411.1 COG4176: ABC-type proline/glycine betaine transporter, permease component, Ralstonia solanacearum; KEGG, K02001 YP_001949412.1 COG4175: ABC-type proline/glycine betaine transporter, ATPase component, Ralstonia solanacearum; KEGG, K02000 YP_001949413.1 COG5373: membrane protein, Ralstonia solanacearum YP_001949415.1 KEGG, K00299 YP_001949419.1 COG5295: Autotransporter adhesin, Mesorhizobium loti; contains haemagluttinin domain YP_001949425.1 COG2200: FOG: EAL domain, Pseudomonas aeruginosa YP_001949427.1 COG4770: Acetyl/propionyl-CoA carboxylase, alpha subunit, Ralstonia solanacearum; KEGG, K01968 YP_001949428.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001949429.1 COG4799: Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta), Ralstonia solanacearum; KEGG, K01966 YP_001949430.1 COG1960: Acyl-CoA dehydrogenases, Ralstonia solanacearum; KEGG, K00253 YP_001949433.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001949435.1 COG0639: Diadenosine tetraphosphatase and related serine/threonine protein phosphatases, Sinorhizobium meliloti YP_001949436.1 COG0642: Signal transduction histidine kinase, Sinorhizobium meliloti YP_001949437.1 COG0745: Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain, Pseudomonas aeruginosa; KEGG, K02483 YP_001949439.1 COG2808: Transcriptional regulator, Ralstonia solanacearum; KEGG, K07734 YP_001949440.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00375; contains aminotransferase domain YP_001949441.1 COG5009: Membrane carboxypeptidase/penicillin-binding protein, Ralstonia solanacearum; KEGG, K05364 YP_001949443.1 COG0477: Permeases of the major facilitator superfamily, Bacillus subtilis; KEGG, K08369 YP_001949444.1 COG3264: Small-conductance mechanosensitive channel, Pseudomonas aeruginosa YP_001949445.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00128 YP_001949446.1 COG0833: Amino acid transporters, Ralstonia solanacearum; KEGG, K03293 YP_001949447.1 COG0665: Glycine/D-amino acid oxidases (deaminating), Sinorhizobium meliloti; KEGG, K00540 YP_001949448.1 COG1309: Transcriptional regulator, Ralstonia solanacearum YP_001949449.1 COG1502: Phosphatidylserine/ phosphatidylglycerophosphate/cardiolipin synthases and related enzymes, Ralstonia solanacearum YP_001949450.1 COG1349: Transcriptional regulators of sugar metabolism, Sinorhizobium meliloti YP_001949452.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Sinorhizobium meliloti YP_001949453.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001949454.1 COG2939: Carboxypeptidase C (cathepsin A), Ralstonia solanacearum; KEGG, K01423 YP_001949455.1 COG4934: protease, Clostridium acetobutylicum; KEGG, K08677 YP_001949457.1 COG1280: threonine efflux protein, Pseudomonas aeruginosa YP_001949458.1 COG1522: Transcriptional regulators, Pseudomonas aeruginosa YP_001949459.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949460.1 COG0010: Arginase/agmatinase/formimionoglutamate hydrolase, arginase, Pseudomonas aeruginosa; KEGG, K01480 YP_001949461.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001949462.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001949463.1 COG0583: Transcriptional regulator, Agrobacterium tumefaciens strain C58; KEGG, K03576 YP_001949464.1 COG0306: Phosphate/sulphate permeases, Pseudomonas aeruginosa; KEGG, K03306 YP_001949465.1 COG3826: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum YP_001949466.1 COG0477: Permeases of the major facilitator superfamily, Mesorhizobium loti YP_001949474.1 COG4341: HD phosphohydrolase, Nostoc sp. PCC 7120 YP_001949475.1 COG1012: NAD-dependent aldehyde dehydrogenases, Sinorhizobium meliloti; KEGG, K00135 YP_001949476.1 COG1524: Uncharacterized proteins of the AP superfamily, Sinorhizobium meliloti; KEGG, K01513 YP_001949477.1 COG1177: ABC-type spermidine/putrescine transporter, permease component II, Salmonella typhimurium LT2; KEGG, K02053 YP_001949478.1 COG0555: ABC-type sulfate transporter, permease component, Salmonella typhimurium LT2; KEGG, K02046 YP_001949479.1 COG3842: ABC-type spermidine/putrescine transporters, ATPase components, Brucella melitensis YP_001949480.1 COG1840: ABC-type Fe3+ transporter, periplasmic component, Salmonella typhimurium LT2; KEGG, K02012 YP_001949481.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_001949482.1 COG0477: Permeases of the major facilitator superfamily, Escherichia coli K12; KEGG, K08194 YP_001949483.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001949484.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001949485.1 COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins, Pseudomonas aeruginosa; KEGG, K00457 YP_001949487.1 COG2207: AraC-type DNA-binding domain-containing proteins, Pseudomonas aeruginosa YP_001949489.1 COG0683: ABC-type branched-chain amino acid transporters, periplasmic component, Ralstonia solanacearum YP_001949490.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa YP_001949491.1 COG2259: membrane protein, Escherichia coli O157:H7 YP_001949492.1 COG4154: Fucose dissimilation pathway protein FucU, Sinorhizobium meliloti; KEGG, K02431 YP_001949493.1 apparently involved in cell division YP_001949494.1 COG2721: Altronate dehydratase, Ralstonia solanacearum; KEGG, K01708 YP_001949495.1 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate YP_001949497.1 COG0702: nucleoside-diphosphate-sugar epimerases, Mesorhizobium loti YP_001949498.1 COG0583: Transcriptional regulator, Mesorhizobium loti YP_001949499.1 involved in polyketide biosynthesis related to monooxygenase YP_001949500.1 COG1280: threonine efflux protein, Vibrio cholerae YP_001949501.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Pseudomonas aeruginosa; KEGG, K00837 YP_001949502.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum YP_001949503.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K03535 YP_001949504.1 COG1396: transcriptional regulators, Mesorhizobium loti YP_001949505.1 COG1960: Acyl-CoA dehydrogenases, Pseudomonas aeruginosa YP_001949507.1 COG2011: ABC-type metal ion transporter, permease component, Pseudomonas aeruginosa; KEGG, K02072 YP_001949508.1 COG1135: ABC-type metal ion transporter, ATPase component, Pseudomonas aeruginosa; KEGG, K02071 YP_001949509.1 COG2141: Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases, Pseudomonas aeruginosa; KEGG, K04091 YP_001949510.1 COG1464: ABC-type metal ion transporter, periplasmic component/surface antigen, Pseudomonas aeruginosa; KEGG, K02073 YP_001949511.1 COG3493: Na+/citrate symporter, Bacillus subtilis YP_001949512.1 COG4191: Signal transduction histidine kinase regulating C4-dicarboxylate transporter, Ralstonia solanacearum YP_001949513.1 COG2204: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains, Pseudomonas aeruginosa YP_001949518.1 COG0596: hydrolases or acyltransferases (alpha/beta hydrolase superfamily) , Pseudomonas aeruginosa YP_001949519.1 COG4125: membrane protein, Pseudomonas aeruginosa YP_001949520.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949521.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001949522.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001949523.1 COG5476: Uncharacterized conserved protein, Ralstonia solanacearum YP_001949524.1 KEGG, K07172 YP_001949525.1 toxin of the ChpB-ChpS toxin-antitoxin system YP_001949526.1 COG1538: Outer membrane protein, Ralstonia solanacearum YP_001949527.1 COG0841: Cation/multidrug efflux pump, Ralstonia solanacearum YP_001949528.1 COG0845: Membrane-fusion protein, Ralstonia solanacearum YP_001949529.1 COG0657: Esterase/lipase, Ralstonia solanacearum; KEGG, K01046 YP_001949530.1 COG0583: Transcriptional regulator, Ralstonia solanacearum; CeoR protein YP_001949532.1 COG5042: Purine nucleoside permease, Ralstonia solanacearum YP_001949534.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001949535.1 COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily, Mesorhizobium loti YP_001949536.1 COG1167: Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs, Ralstonia solanacearum; KEGG, K00375; contains aminotransferase domain YP_001949537.1 COG0160: 4-aminobutyrate aminotransferase and related aminotransferases, Ralstonia solanacearum; KEGG, K00823 YP_001949538.1 COG1012: NAD-dependent aldehyde dehydrogenases, Pseudomonas aeruginosa; KEGG, K00135 YP_001949539.1 COG0840: Methyl-accepting chemotaxis protein, Ralstonia solanacearum; KEGG, K03776 YP_001949540.1 catalyzes the thiolytic cleavage of beta-ketoadipyl-CoA to succinate and acetyl-CoA YP_001949541.1 COG1414: Transcriptional regulator, Ralstonia solanacearum; KEGG, K02624 YP_001949542.1 COG0477: Permeases of the major facilitator superfamily, Pseudomonas aeruginosa; KEGG, K03762 YP_001949543.1 COG1473: Metal-dependent amidase/aminoacylase/carboxypeptidase, Pseudomonas aeruginosa; KEGG, K01451 YP_001949544.1 COG1309: Transcriptional regulator, Mesorhizobium loti YP_001949545.1 COG0604: NADPH:quinone reductase and related Zn-dependent oxidoreductases, Ralstonia solanacearum; KEGG, K00344 YP_001949546.1 COG2128: Uncharacterized conserved protein, Ralstonia solanacearum YP_001949547.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001949548.1 COG0583: Transcriptional regulator, Ralstonia solanacearum YP_001949549.1 catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid YP_001949550.1 COG1902: NADH:flavin oxidoreductases, Old Yellow Enzyme family, Pseudomonas aeruginosa; KEGG, K00540 YP_001949551.1 COG2252: Permeases, Ralstonia solanacearum; KEGG, K06901 YP_001949552.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949553.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Salmonella typhimurium LT2; KEGG, K02030 YP_001949554.1 OrfA YP_001949555.1 OrfB YP_001949556.1 COG3608: deacylase, Pseudomonas aeruginosa; KEGG, K06987 YP_001949557.1 KEGG, K02073 YP_001949558.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001949562.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Ralstonia solanacearum; KEGG, K02014 YP_001949563.1 COG3720: heme degradation protein, Ralstonia solanacearum; KEGG, K07225 YP_001949564.1 COG4558: ABC-type hemin transporter, periplasmic component, Yersinia pestis; KEGG, K02016 YP_001949565.1 COG0609: ABC-type Fe3+-siderophore transporter, permease component, Deinococcus radiodurans; KEGG, K02015 YP_001949566.1 with HmuTU is involved in the import of hemin YP_001949567.1 COG2860: membrane protein, Pseudomonas aeruginosa YP_001949568.1 COG0744: Membrane carboxypeptidase (penicillin-binding protein), Mesorhizobium loti; KEGG, K05366 YP_001949569.1 COG3570: Streptomycin 6-kinase, Sinorhizobium meliloti YP_001949570.1 COG3257: Uncharacterized protein, possibly involved in glyoxylate utilization, Pseudomonas aeruginosa YP_001949573.1 COG0537: Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases, Ralstonia solanacearum; KEGG, K02503; involved in cell-cycle regulation YP_001949574.1 COG1680: Beta-lactamase class C and other penicillin binding proteins, Sinorhizobium meliloti; KEGG, K01453 YP_001949575.1 COG0625: Glutathione S-transferase, Pseudomonas aeruginosa; KEGG, K00799 YP_001949576.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001949578.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Pseudomonas aeruginosa YP_001949582.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949583.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001949585.1 COG0625: Glutathione S-transferase, Sinorhizobium meliloti; KEGG, K00799 YP_001949586.1 COG0491: Zn-dependent hydrolases, including glyoxylases, Synechocystis; KEGG, K01069 YP_001949587.1 specific inhibitor of chromosomal initiation of replication in vitro; inds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001949589.1 COG2008: Threonine aldolase, Pseudomonas aeruginosa; KEGG, K01620 YP_001949592.1 COG1271: Cytochrome bd-type quinol oxidase, subunit 1, Pseudomonas aeruginosa; KEGG, K00425 YP_001949593.1 COG1294: Cytochrome bd-type quinol oxidase, subunit 2, Pseudomonas aeruginosa; KEGG, K00426 YP_001949596.1 involved in heme utilization or adhesion YP_001949599.1 COG5361: Uncharacterized conserved protein, Ralstonia solanacearum YP_001949600.1 COG2217: Cation transport ATPase, Pseudomonas aeruginosa; KEGG, K01533 YP_001949604.1 COG1285: Uncharacterized membrane protein, Yersinia pestis; KEGG, K07507 YP_001949605.1 COG2942: N-acyl-D-glucosamine 2-epimerase, Ralstonia solanacearum; KEGG, K01809 YP_001949606.1 COG0840: Methyl-accepting chemotaxis protein, Salmonella typhimurium LT2; KEGG, K05875 YP_001949607.1 COG2050: Uncharacterized protein, possibly involved in aromatic compounds catabolism, Deinococcus radiodurans YP_001949608.1 COG1804: acyl-CoA transferases/carnitine dehydratase, Mesorhizobium loti; KEGG, K01796 YP_001949609.1 COG2828: Uncharacterized protein conserved in bacteria, Ralstonia solanacearum; PrpF protein YP_001949610.1 Catalyzes the conversion of citrate to isocitrate YP_001949611.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_001949612.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001949613.1 COG3829: Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains, Ralstonia solanacearum; KEGG, K02688 YP_001949614.1 COG5516: Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding, Mesorhizobium loti; contains a Zn-ribbon-like motif YP_001949615.1 COG0346: Lactoylglutathione lyase and related lyases, Brucella melitensis YP_001949616.1 COG0179: 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway), Yersinia pestis; KEGG, K01828 YP_001949617.1 COG1414: Transcriptional regulator, Brucella melitensis YP_001949619.1 COG1042: Acyl-CoA synthetase (NDP forming), Mesorhizobium loti; KEGG, K09181 YP_001949620.1 COG2916: DNA-binding protein H-NS, Ralstonia solanacearum YP_001949623.1 COG3829: Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains, Pseudomonas aeruginosa YP_001949624.1 COG2610: H+/gluconate symporter and related permeases, Ralstonia solanacearum YP_001949627.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Salmonella typhimurium LT2; KEGG, K03825 YP_001949628.1 COG3511: Phospholipase C, Pseudomonas aeruginosa; KEGG, K01114 YP_001949630.1 COG0586: Uncharacterized membrane-associated protein, Ralstonia solanacearum YP_001949632.1 COG4608: ABC-type oligopeptide transporter, ATPase component, Escherichia coli O157:H7; KEGG, K02032 YP_001949633.1 COG0444: ABC-type dipeptide/oligopeptide/nickel transporter, ATPase component, Yersinia pestis; KEGG, K02031 YP_001949634.1 COG1173: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Vibrio cholerae; KEGG, K02034 YP_001949635.1 COG0601: ABC-type dipeptide/oligopeptide/nickel transporters, permease components, Yersinia pestis; KEGG, K02033 YP_001949636.1 COG4166: ABC-type oligopeptide transporter, periplasmic component, Yersinia pestis; KEGG, K02035 YP_001949637.1 COG1396: transcriptional regulators, Pseudomonas aeruginosa YP_001949638.1 COG3104: Dipeptide/tripeptide permease, Salmonella typhimurium LT2; KEGG, K03305 YP_001949640.1 COG4645: Uncharacterized protein conserved in bacteria, Mesorhizobium loti YP_001949641.1 COG2962: permeases, Pseudomonas aeruginosa; KEGG, K05786; RarD protein YP_001949642.1 catalyzes the hydrolysis of acylphosphate YP_001949643.1 COG0451: Nucleoside-diphosphate-sugar epimerases, Nostoc sp. PCC 7120; KEGG, K00091 YP_001949644.1 COG3064: Membrane protein involved in colicin uptake, Salmonella typhimurium LT2 YP_001949645.1 COG0463: Glycosyltransferases involved in cell wall biogenesis, Nostoc sp. PCC 7120; involved in cell wall biogenesis YP_001949646.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001949647.1 COG0535: Fe-S oxidoreductases, Synechocystis YP_001949650.1 COG3805: Aromatic ring-cleaving dioxygenase, Nostoc sp. PCC 7120; KEGG, K00516 YP_001949652.1 COG1272: membrane protein, hemolysin III homolog, Neisseria meningitidis Z2491; KEGG, K07036 YP_001949653.1 COG2879: Uncharacterized small protein, Ralstonia solanacearum YP_001949654.1 COG1966: Carbon starvation protein, membrane protein, Ralstonia solanacearum; KEGG, K06200 YP_001949655.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa; CatR protein YP_001949656.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum YP_001949657.1 COG0251: translation initiation inhibitor, yjgF family, Sinorhizobium meliloti; KEGG, K07567 YP_001949658.1 catalyzes the degradation of 2-hydro-1,2-dihydroxy benzoate to catechol YP_001949659.1 COG0543: 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases, Pseudomonas aeruginosa; KEGG, K05784 YP_001949660.1 COG5517: Small subunit of phenylpropionate dioxygenase, Corynebacterium glutamicum; KEGG, K08686 YP_001949661.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Pseudomonas aeruginosa; KEGG, K05549 YP_001949662.1 COG3485: Protocatechuate 3,4-dioxygenase beta subunit, Pseudomonas aeruginosa; KEGG, K03381 YP_001949663.1 COG4829: Muconolactone delta-isomerase, Pseudomonas aeruginosa; KEGG, K03464 YP_001949664.1 COG4948: L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily, Pseudomonas aeruginosa; KEGG, K01856 YP_001949666.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001949667.1 COG3132: Uncharacterized protein conserved in bacteria, Vibrio cholerae YP_001949669.1 COG1028: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases), Ralstonia solanacearum; KEGG, K00072 YP_001949670.1 COG2188: Transcriptional regulators, Pseudomonas aeruginosa; KEGG, K05836 YP_001949671.1 COG5285: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin, Mesorhizobium loti; involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin YP_001949672.1 COG0834: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain, Pseudomonas aeruginosa; KEGG, K02030 YP_001949673.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949674.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001949675.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_001949677.1 COG0454: Histone acetyltransferase HPA2 and related acetyltransferases, Ralstonia solanacearum YP_001949678.1 COG5434: Endopolygalacturonase, Ralstonia solanacearum YP_001949679.1 COG0001: Glutamate-1-semialdehyde aminotransferase, Pseudomonas aeruginosa; KEGG, K01845 YP_001949681.1 COG3203: Outer membrane protein (porin), Ralstonia solanacearum YP_001949682.1 COG0477: Permeases of the major facilitator superfamily, Ralstonia solanacearum; KEGG, K05819 YP_001949683.1 COG1846: Transcriptional regulators, Ralstonia solanacearum YP_001949684.1 COG1802: Transcriptional regulators, Agrobacterium tumefaciens strain C58; VanR protein YP_001949685.1 COG4638: Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit, Ralstonia solanacearum; KEGG, K03862 YP_001949686.1 COG1018: Flavodoxin reductases (ferredoxin-NADPH reductases) family 1, Ralstonia solanacearum; KEGG, K03863 YP_001949687.1 catalyzes the conversion of ferulic acid to feruloyl-CoA YP_001949688.1 COG1012: NAD-dependent aldehyde dehydrogenases, Ralstonia solanacearum; KEGG, K00141 YP_001949689.1 catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA YP_001949690.1 COG3386: Gluconolactonase, Ralstonia solanacearum YP_001949691.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001949692.1 Part of the ABC transporter complex AraFGH involved in the high affinity transport of arabinose YP_001949693.1 COG1879: ABC-type sugar transporter, periplasmic component, Ralstonia solanacearum YP_001949694.1 COG0673: dehydrogenases and related proteins, Agrobacterium tumefaciens strain C58; KEGG, K00035 YP_001949695.1 COG0329: Dihydrodipicolinate synthase/N-acetylneuraminate lyase, Agrobacterium tumefaciens strain C58; KEGG, K01714 YP_001949696.1 COG0477: Permeases of the major facilitator superfamily, Caulobacter vibrioides YP_001949697.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_001949698.1 COG0583: Transcriptional regulator, Pseudomonas aeruginosa YP_001949699.1 COG1629: Outer membrane receptor proteins, mostly Fe transport, Ralstonia solanacearum YP_001949700.1 COG1609: Transcriptional regulators, Ralstonia solanacearum YP_001949701.1 COG3839: ABC-type sugar transporters, ATPase components, Yersinia pestis; KEGG, K02023 YP_001949702.1 COG1874: Beta-galactosidase, Thermotoga maritima; KEGG, K01190 YP_001949703.1 COG1653: ABC-type sugar transporter, periplasmic component, Sinorhizobium meliloti YP_001949704.1 COG1175: ABC-type sugar transporters, permease components, Sinorhizobium meliloti; KEGG, K02025 YP_001949705.1 COG0395: ABC-type sugar transporter, permease component, Sinorhizobium meliloti; KEGG, K02026 YP_001949706.1 COG1352: Methylase of chemotaxis methyl-accepting proteins, Methanosarcina acetivorans str.C2A; CheR protein; KEGG, K00575 YP_001949707.1 COG2201: Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain, Sinorhizobium meliloti; CheB protein; KEGG, K03412 YP_001949708.1 COG2070: Dioxygenases related to 2-nitropropane dioxygenase, Caulobacter vibrioides YP_001949709.1 COG3193: Uncharacterized protein, possibly involved in utilization of glycolate and propanediol, Pseudomonas aeruginosa YP_001949710.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_001949711.1 COG2199: FOG: GGDEF domain, Ralstonia solanacearum; contains GGDEF domain YP_001949712.1 COG4564: Signal transduction histidine kinase, Ralstonia solanacearum; KEGG, K02480 YP_001949713.1 COG2197: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain, Brucella melitensis; KEGG, K07684; NarL protein YP_001949714.1 COG2854: ABC-type transporter involved in resistance to organic solvents, auxiliary component, Ralstonia solanacearum; involved in resistance to organic solvents YP_001949715.1 KEGG, K07003 YP_001949716.1 COG2853: Surface lipoprotein, Ralstonia solanacearum; KEGG, K04754 YP_001949717.1 COG3523: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001949718.1 COG3455: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001949720.1 COG3519: Uncharacterized protein conserved in bacteria, Salmonella typhimurium LT2 YP_001949722.1 COG1657: Squalene cyclase, Nostoc sp. PCC 7120; KEGG, K06045 YP_001949724.1 COG1562: Phytoene/squalene synthetase, Neisseria meningitidis MC58; KEGG, K02291 YP_001949727.1 contains GGDEF domain YP_001949728.1 COG1776: Chemotaxis protein CheC, inhibitor of MCP methylation, Vibrio cholerae; CheC protein; KEGG, K03410 YP_001949729.1 COG0784: FOG: CheY-like receiver, Vibrio cholerae; KEGG, K05971 YP_001949730.1 COG0642: Signal transduction histidine kinase, Caulobacter vibrioides; contains a signal receiver domain YP_001949731.1 COG0431: flavoprotein, Ralstonia solanacearum YP_001949732.1 COG1393: Arsenate reductase and related proteins, glutaredoxin family, Vibrio cholerae; KEGG, K00537 YP_001949733.1 COG1192: ATPases involved in chromosome partitioning, Ralstonia solanacearum; ParA3 protein YP_001949734.1 COG1475: transcriptional regulators, Ralstonia solanacearum; ParB protein YP_001949735.1 RepA3 protein