-- dump date 20140619_015045 -- class Genbank::misc_feature -- table misc_feature_note -- id note 272560000001 gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516 272560000002 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454 272560000003 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 4.2, E-value 2.5e-06 272560000004 11 probable transmembrane helices predicted for BPSL0002 by TMHMM2.0 at aa 26-48, 53-75, 108-130, 137-156, 171-193, 200-222, 242-274, 283-305, 315-337, 349-366 and 381-403 272560000005 bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747 272560000006 Uncharacterized conserved protein [Function unknown]; Region: COG4121 272560000007 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; Region: MnmC_Cterm; TIGR03197 272560000008 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -77.4, E-value 0.00073 272560000009 histone-like DNA-binding protein HU; Region: HU; cd13831 272560000010 dimer interface [polypeptide binding]; other site 272560000011 DNA binding site [nucleotide binding] 272560000012 Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein , score 169.4, E-value 4e-48 272560000013 PS00045 Bacterial histone-like DNA-binding proteins signature. 272560000014 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 272560000015 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 272560000016 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833 272560000017 Pfam match to entry PF02492 cobW, Cobalamin synthesis protein/P47K , score 609.9, E-value 9.9e-181 272560000018 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000019 Signal peptide predicted for BPSL0006 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.871 between residues 24 and 25; signal peptide 272560000020 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 272560000021 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560000022 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560000023 catalytic residue [active] 272560000024 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain , score 94.9, E-value 1.1e-25 272560000025 Signal peptide predicted for BPSL0007 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 28 and 29; signal peptide 272560000026 type II secretion system protein D; Region: type_II_gspD; TIGR02517 272560000027 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560000028 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560000029 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560000030 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560000031 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 27.8, E-value 1.2e-07 272560000032 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 15.2, E-value 0.00032 272560000033 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 354.6, E-value 6.9e-104 272560000034 Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157 272560000035 type II secretion system protein E; Region: type_II_gspE; TIGR02533 272560000036 PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129 272560000037 Walker A motif; other site 272560000038 ATP binding site [chemical binding]; other site 272560000039 Walker B motif; other site 272560000040 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score 625.1, E-value 2.5e-185 272560000041 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000042 PS00662 Bacterial type II secretion system protein E signature. 272560000043 type II secretion system protein F; Region: GspF; TIGR02120 272560000044 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560000045 Ceramidase; Region: Ceramidase; pfam05875 272560000046 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560000047 Pfam match to entry PF00482 GSPII_F, Bacterial type II secretion system protein F domain , score 437.9, E-value 5.9e-129 272560000048 3 probable transmembrane helices predicted for BPSL0009 by TMHMM2.0 at aa 167-189, 220-239 and 376-398 272560000049 Signal peptide predicted for BPSL0010 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.780 between residues 32 and 33; signal peptide 272560000050 Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356 272560000051 type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710 272560000052 prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532 272560000053 Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334 272560000054 PS00409 Prokaryotic N-terminal methylation site. 272560000055 1 probable transmembrane helix predicted for BPSL0011 by TMHMM2.0 at aa 17-39 272560000056 Pfam match to entry PF00114 pilin, Pilin (bacterial filament) , score 20.4, E-value 2.6e-06 272560000057 Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544 272560000058 type II secretion system protein H; Region: typeII_sec_gspH; TIGR01708 272560000059 Type II transport protein GspH; Region: GspH; pfam12019 272560000060 PS00409 Prokaryotic N-terminal methylation site. 272560000061 1 probable transmembrane helix predicted for BPSL0012 by TMHMM2.0 at aa 52-74 272560000062 type II secretion system protein I; Region: gspI; TIGR01707 272560000063 Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501 272560000064 Pfam match to entry PF02501 GSPII_IJ, Bacterial type II secretion system protein I/J , score 14.8, E-value 5.1e-06 272560000065 1 probable transmembrane helix predicted for BPSL0013 by TMHMM2.0 at aa 21-43 272560000066 Prokaryotic N-terminal methylation motif; Region: N_methyl; pfam07963 272560000067 Type II secretory pathway pseudopilin; Region: PulG; pfam11773 272560000068 1 probable transmembrane helix predicted for BPSL0014 by TMHMM2.0 at aa 31-53 272560000069 PS00409 Prokaryotic N-terminal methylation site. 272560000070 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl19066 272560000071 Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165 272560000072 Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934 272560000073 Pfam match to entry PF03934 GspK, General secretion pathway protein K , score 131.7, E-value 8.7e-37 272560000074 1 probable transmembrane helix predicted for BPSL0015 by TMHMM2.0 at aa 21-43 272560000075 type II secretion system protein L; Region: typeII_sec_gspL; TIGR01709 272560000076 Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134 272560000077 GspL periplasmic domain; Region: GspL_C; pfam12693 272560000078 1 probable transmembrane helix predicted for BPSL0016 by TMHMM2.0 at aa 332-354 272560000079 Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612 272560000080 1 probable transmembrane helix predicted for BPSL0017 by TMHMM2.0 at aa 23-45 272560000081 Type II secretion system (T2SS), protein N; Region: T2SN; pfam01203 272560000082 1 probable transmembrane helix predicted for BPSL0018 by TMHMM2.0 at aa 27-49 272560000083 Signal peptide predicted for BPSL0019 by SignalP 2.0 HMM (Signal peptide probabilty 0.963) with cleavage site probability 0.351 between residues 31 and 32; signal peptide 272560000084 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560000085 Outer membrane efflux protein; Region: OEP; pfam02321 272560000086 Outer membrane efflux protein; Region: OEP; pfam02321 272560000087 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 202.7, E-value 3.6e-58 272560000088 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 169.9, E-value 2.7e-48 272560000089 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000090 1 probable transmembrane helix predicted for BPSL0020 by TMHMM2.0 at aa 48-70 272560000091 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560000092 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 272560000093 Pfam match to entry PF01047 MarR, MarR family , score 87.7, E-value 1.5e-23 272560000094 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560000095 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560000096 putative substrate translocation pore; other site 272560000097 13 probable transmembrane helices predicted for BPSL0022 by TMHMM2.0 at aa 21-43, 63-85, 92-111, 116-138, 151-173, 178-200, 212-234, 239-261, 281-303, 313-335, 347-369, 379-401 and 490-507 272560000098 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -85.4, E-value 7.8e-05 272560000099 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560000100 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560000101 The C-terminal substrate binding domain of LysR-like transcriptional regulator CidR, contains the type 2 periplasmic binding fold; Region: PBP2_CidR; cd08438 272560000102 putative dimerization interface [polypeptide binding]; other site 272560000103 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 157.0, E-value 2e-44 272560000104 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 109.4, E-value 4.4e-30 272560000105 PS00044 Bacterial regulatory proteins, lysR family signature. 272560000106 Predicted helix-turn-helix motif with score 1861.000, SD 5.53 at aa 16-37, sequence QSFTVAAEQMHVTQPTISKMVK 272560000107 LrgA family; Region: LrgA; cl00608 272560000108 Pfam match to entry PF03788 LrgA, LrgA family , score 107.2, E-value 2e-29 272560000109 3 probable transmembrane helices predicted for BPSL0024 by TMHMM2.0 at aa 24-46, 59-81 and 91-113 272560000110 LrgB-like family; Region: LrgB; cl00596 272560000111 6 probable transmembrane helices predicted for BPSL0025 by TMHMM2.0 at aa 20-42, 55-77, 87-106, 113-135, 173-195 and 228-250 272560000112 flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021 272560000113 Pfam match to entry PF03748 FliL, Flagellar basal body-associated protein FliL , score 112.1, E-value 6.7e-31 272560000114 1 probable transmembrane helix predicted for BPSL0026 by TMHMM2.0 at aa 36-58 272560000115 flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666 272560000116 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 272560000117 Pfam match to entry PF02154 FliM, Flagellar motor switch protein FliM , score 339.4, E-value 2.5e-99 272560000118 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein , score 11.7, E-value 0.0016 272560000119 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 272560000120 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein , score 113.6, E-value 2.4e-31 272560000121 Flagellar biosynthesis protein, FliO; Region: FliO; pfam04347 272560000122 1 probable transmembrane helix predicted for BPSL0029 by TMHMM2.0 at aa 70-92 272560000123 Signal peptide predicted for BPSL0030 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.732 between residues 29 and 30; signal peptide 272560000124 flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699 272560000125 5 probable transmembrane helices predicted for BPSL0030 by TMHMM2.0 at aa 13-35, 55-77, 97-114, 191-213 and 226-245 272560000126 Pfam match to entry PF00813 FliP, FliP family , score 383.9, E-value 1e-112 272560000127 PS01060 Flagella transport protein fliP family signature 1. 272560000128 PS01061 Flagella transport protein fliP family signature 2. 272560000129 flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700 272560000130 Pfam match to entry PF01313 Bac_export_3, Bacterial export proteins, family 3 , score 134.8, E-value 1.1e-37 272560000131 2 probable transmembrane helices predicted for BPSL0031 by TMHMM2.0 at aa 15-37 and 49-71 272560000132 flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701 272560000133 Pfam match to entry PF01311 Bac_export_1, Bacterial export proteins, family 1 , score 246.3, E-value 2.8e-71 272560000134 7 probable transmembrane helices predicted for BPSL0032 by TMHMM2.0 at aa 12-34, 44-66, 71-93, 98-115, 128-150, 183-205 and 212-234 272560000135 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg6; cd04781 272560000136 Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044 272560000137 DNA binding residues [nucleotide binding] 272560000138 putative dimer interface [polypeptide binding]; other site 272560000139 putative metal binding residues [ion binding]; other site 272560000140 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 27.5, E-value 2e-05 272560000141 Predicted helix-turn-helix motif with score 1403.000, SD 3.97 at aa 4-25, sequence LDIAEVAQRSGVPASALRYYEE 272560000142 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560000143 S-adenosylmethionine binding site [chemical binding]; other site 272560000144 Signal peptide predicted for BPSL0035 by SignalP 2.0 HMM (Signal peptide probabilty 0.972) with cleavage site probability 0.571 between residues 20 and 21; signal peptide 272560000145 Protein of unknown function (DUF2938); Region: DUF2938; pfam11158 272560000146 4 probable transmembrane helices predicted for BPSL0035 by TMHMM2.0 at aa 5-27, 73-95, 102-124 and 144-166 272560000147 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 272560000148 Signal peptide predicted for BPSL0036 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 28 and 29; signal peptide 272560000149 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560000150 PS00217 Sugar transport proteins signature 2. 272560000151 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 272560000152 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 272560000153 Walker A/P-loop; other site 272560000154 ATP binding site [chemical binding]; other site 272560000155 Q-loop/lid; other site 272560000156 ABC transporter signature motif; other site 272560000157 Walker B; other site 272560000158 D-loop; other site 272560000159 H-loop/switch region; other site 272560000160 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 218.5, E-value 6.3e-63 272560000161 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000162 PS00211 ABC transporters family signature. 272560000163 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 272560000164 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560000165 dimer interface [polypeptide binding]; other site 272560000166 conserved gate region; other site 272560000167 putative PBP binding loops; other site 272560000168 ABC-ATPase subunit interface; other site 272560000169 6 probable transmembrane helices predicted for BPSL0038 by TMHMM2.0 at aa 31-50, 95-114, 121-143, 147-169, 201-223 and 246-268 272560000170 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 23.6, E-value 0.00029 272560000171 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 272560000172 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560000173 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560000174 dimer interface [polypeptide binding]; other site 272560000175 phosphorylation site [posttranslational modification] 272560000176 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560000177 ATP binding site [chemical binding]; other site 272560000178 Mg2+ binding site [ion binding]; other site 272560000179 G-X-G motif; other site 272560000180 2 probable transmembrane helices predicted for BPSL0039 by TMHMM2.0 at aa 33-50 and 190-209 272560000181 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 52.6, E-value 5.5e-13 272560000182 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 140.3, E-value 2.2e-39 272560000183 transcriptional regulatory protein TctD; Provisional; Region: PRK15479 272560000184 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560000185 active site 272560000186 phosphorylation site [posttranslational modification] 272560000187 intermolecular recognition site; other site 272560000188 dimerization interface [polypeptide binding]; other site 272560000189 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560000190 DNA binding site [nucleotide binding] 272560000191 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 150.4, E-value 2.1e-42 272560000192 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 71.4, E-value 1.3e-18 272560000193 Signal peptide predicted for BPSL0036 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 16 and 17; signal peptide 272560000194 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560000195 trimer interface [polypeptide binding]; other site 272560000196 eyelet of channel; other site 272560000197 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000198 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -115.8, E-value 0.11 272560000199 Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189 272560000200 DNA methylase; Region: N6_N4_Mtase; pfam01555 272560000201 PS00092 N-6 Adenine-specific DNA methylases signature. 272560000202 Pfam match to entry PF01555 N6_N4_Mtase, DNA methylase , score 42.5, E-value 6.4e-10 272560000203 Restriction endonuclease [Defense mechanisms]; Region: COG3587 272560000204 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560000205 ATP binding site [chemical binding]; other site 272560000206 putative Mg++ binding site [ion binding]; other site 272560000207 Signal peptide predicted for BPSL0044 by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.984 between residues 19 and 20; signal peptide 272560000208 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560000209 trimer interface [polypeptide binding]; other site 272560000210 eyelet of channel; other site 272560000211 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -118.0, E-value 0.14 272560000212 AraC-binding-like domain; Region: AraC_binding_2; pfam14525 272560000213 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560000214 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000215 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000216 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 37.4, E-value 2.1e-08 272560000217 Predicted helix-turn-helix motif with score 1253.000, SD 3.45 at aa 229-250, sequence LSIDRIARELRCSKRYLHRIFE 272560000218 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 36.7, E-value 3.4e-08 272560000219 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560000220 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560000221 Walker A/P-loop; other site 272560000222 ATP binding site [chemical binding]; other site 272560000223 Q-loop/lid; other site 272560000224 ABC transporter signature motif; other site 272560000225 Walker B; other site 272560000226 D-loop; other site 272560000227 H-loop/switch region; other site 272560000228 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 125.9, E-value 5e-35 272560000229 PS00211 ABC transporters family signature. 272560000230 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000231 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560000232 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560000233 Walker A/P-loop; other site 272560000234 ATP binding site [chemical binding]; other site 272560000235 Q-loop/lid; other site 272560000236 ABC transporter signature motif; other site 272560000237 Walker B; other site 272560000238 D-loop; other site 272560000239 H-loop/switch region; other site 272560000240 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 118.4, E-value 8.5e-33 272560000241 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000242 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560000243 TM-ABC transporter signature motif; other site 272560000244 9 probable transmembrane helices predicted for BPSL0048 by TMHMM2.0 at aa 21-43, 48-70, 75-97, 102-124, 129-151, 180-197, 231-253, 268-290 and 302-324 272560000245 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560000246 TM-ABC transporter signature motif; other site 272560000247 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 34.1, E-value 3.2e-08 272560000248 8 probable transmembrane helices predicted for BPSL0049 by TMHMM2.0 at aa 13-35, 45-67, 76-98, 120-142, 163-185, 195-217, 222-244 and 249-271 272560000249 Type I periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_7; cd06341 272560000250 putative ligand binding site [chemical binding]; other site 272560000251 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000252 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560000253 NAD(P) binding site [chemical binding]; other site 272560000254 catalytic residues [active] 272560000255 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 758.9, E-value 1.4e-225 272560000256 PS00070 Aldehyde dehydrogenases cysteine active site. 272560000257 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560000258 Ketosteroid isomerase-related protein [General function prediction only]; Region: COG3631 272560000259 Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703 272560000260 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560000261 classical (c) SDRs; Region: SDR_c; cd05233 272560000262 NAD(P) binding site [chemical binding]; other site 272560000263 active site 272560000264 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 237.6, E-value 1.1e-68 272560000265 PS00061 Short-chain dehydrogenases/reductases family signature. 272560000266 choline dehydrogenase; Validated; Region: PRK02106 272560000267 putative FAD-binding dehydrogenase; Reviewed; Region: PRK12834 272560000268 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560000269 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560000270 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score 662.7, E-value 1.2e-196 272560000271 PS00624 GMC oxidoreductases signature 2. 272560000272 PS00623 GMC oxidoreductases signature 1. 272560000273 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000274 Predicted transcriptional regulators [Transcription]; Region: COG1695 272560000275 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560000276 putative Zn2+ binding site [ion binding]; other site 272560000277 putative DNA binding site [nucleotide binding]; other site 272560000278 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family , score 93.0, E-value 3.8e-25 272560000279 Predicted membrane protein [Function unknown]; Region: COG4709 272560000280 3 probable transmembrane helices predicted for BPSL0057 by TMHMM2.0 at aa 82-104, 111-133 and 344-366 272560000281 This CD includes the dihydrorhizobitoxine fatty acid desaturase (RtxC) characterized in Bradyrhizobium japonicum USDA110, and other related proteins. Dihydrorhizobitoxine desaturase is reported to be involved in the final step of rhizobitoxine...; Region: Rhizobitoxine-FADS-like; cd03510 272560000282 putative di-iron ligands [ion binding]; other site 272560000283 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 35.3, E-value 4.3e-08 272560000284 4 probable transmembrane helices predicted for BPSL0058 by TMHMM2.0 at aa 27-49, 53-75, 197-219 and 223-240 272560000285 PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223 272560000286 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560000287 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 272560000288 conserved cys residue [active] 272560000289 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000290 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000291 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 37.8, E-value 1.6e-08 272560000292 PS00041 Bacterial regulatory proteins, araC family signature. 272560000293 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 17.1, E-value 0.028 272560000294 Predicted helix-turn-helix motif with score 1655.000, SD 4.82 at aa 245-266, sequence PTLAELAARAAMSERTLSRRFA 272560000295 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560000296 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560000297 active site 272560000298 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 107.4, E-value 1.9e-29 272560000299 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 189.9, E-value 2.7e-54 272560000300 PS00072 Acyl-CoA dehydrogenases signature 1. 272560000301 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 218.7, E-value 5.6e-63 272560000302 PS00073 Acyl-CoA dehydrogenases signature 2. 272560000303 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 177.8, E-value 1.2e-50 272560000304 acetyl-CoA acetyltransferase; Validated; Region: PRK08242 272560000305 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560000306 dimer interface [polypeptide binding]; other site 272560000307 active site 272560000308 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 202.1, E-value 5.7e-58 272560000309 PS00737 Thiolases signature 2. 272560000310 PS00099 Thiolases active site. 272560000311 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 272560000312 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560000313 substrate binding site [chemical binding]; other site 272560000314 oxyanion hole (OAH) forming residues; other site 272560000315 trimer interface [polypeptide binding]; other site 272560000316 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560000317 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560000318 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 133.1, E-value 3.4e-37 272560000319 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 248.0, E-value 8.6e-72 272560000320 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 86.0, E-value 4.9e-23 272560000321 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560000322 PS00387 Inorganic pyrophosphatase signature. 272560000323 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 196.2, E-value 3.4e-56 272560000324 Signal peptide predicted for BPSL0065 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.950 between residues 28 and 29; signal peptide 272560000325 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000326 Surface antigen [Cell envelope biogenesis, outer membrane]; Region: LipA; COG4520 272560000327 2 probable transmembrane helices predicted for BPSL0066 by TMHMM2.0 at aa 12-34 and 98-120 272560000328 Signal peptide predicted for BPSL0068 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.287 between residues 30 and 31; signal peptide 272560000329 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000330 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 272560000331 Arabinofuranosyltransferase A C terminal; Region: AftA_C; pfam12249 272560000332 1 probable transmembrane helix predicted for BPSL0069 by TMHMM2.0 at aa 83-105 272560000333 RNA polymerase sigma factor, SigM family; Region: SigM_subfam; TIGR02950 272560000334 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560000335 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560000336 DNA binding residues [nucleotide binding] 272560000337 Predicted helix-turn-helix motif with score 1218.000, SD 3.34 at aa 118-139, sequence FSYQEVAELLDIPIGTVMSRLS 272560000338 Catalase-like heme-binding proteins similar to the uncharacterized srpA; Region: srpA_like; cd08153 272560000339 putative heme binding pocket [chemical binding]; other site 272560000340 Pfam match to entry PF00199 catalase, Catalase , score -166.3, E-value 2.3e-08 272560000341 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 272560000342 4 probable transmembrane helices predicted for BPSL0072 by TMHMM2.0 at aa 12-34, 44-63, 84-106 and 141-163 272560000343 DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939 272560000344 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560000345 ATP binding site [chemical binding]; other site 272560000346 Mg2+ binding site [ion binding]; other site 272560000347 G-X-G motif; other site 272560000348 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 272560000349 anchoring element; other site 272560000350 dimer interface [polypeptide binding]; other site 272560000351 ATP binding site [chemical binding]; other site 272560000352 TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366 272560000353 active site 272560000354 putative metal-binding site [ion binding]; other site 272560000355 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 272560000356 Pfam match to entry PF00986 DNA_gyraseB_C, DNA gyrase B subunit, carboxyl terminus , score 153.8, E-value 2e-43 272560000357 Pfam match to entry PF01751 Toprim, Toprim domain , score 31.4, E-value 1.4e-06 272560000358 PS00177 DNA topoisomerase II signature. 272560000359 Pfam match to entry PF00204 DNA_gyraseB, DNA gyrase B , score 303.4, E-value 1.8e-88 272560000360 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 94.2, E-value 1.7e-25 272560000361 DNA polymerase III subunit beta; Validated; Region: PRK05643 272560000362 Beta clamp domain. The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria. The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140 272560000363 putative DNA binding surface [nucleotide binding]; other site 272560000364 dimer interface [polypeptide binding]; other site 272560000365 beta-clamp/clamp loader binding surface; other site 272560000366 beta-clamp/translesion DNA polymerase binding surface; other site 272560000367 Pfam match to entry PF02768 DNA_pol3_beta_3, DNA polymerase III beta subunit, C-terminal domain , score 141.5, E-value 9.5e-40 272560000368 Pfam match to entry PF02767 DNA_pol3_beta_2, DNA polymerase III beta subunit, central domain , score 148.4, E-value 8.4e-42 272560000369 Pfam match to entry PF00712 DNA_pol3_beta, DNA polymerase III beta subunit, N-terminal domain , score 102.8, E-value 4.2e-28 272560000370 chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149 272560000371 DnaA N-terminal domain; Region: DnaA_N; pfam11638 272560000372 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560000373 Walker A motif; other site 272560000374 ATP binding site [chemical binding]; other site 272560000375 Walker B motif; other site 272560000376 arginine finger; other site 272560000377 C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571 272560000378 DnaA box-binding interface [nucleotide binding]; other site 272560000379 Pfam match to entry PF00308 bac_dnaA, Bacterial dnaA protein , score 608.2, E-value 3.3e-180 272560000380 PS01008 DnaA protein signature. 272560000381 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000382 50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399 272560000383 Ribonuclease P; Region: Ribonuclease_P; cl00457 272560000384 Pfam match to entry PF00825 Ribonuclease_P, Ribonuclease P , score 38.0, E-value 7.1e-10 272560000385 hypothetical protein; Validated; Region: PRK00041 272560000386 Pfam match to entry PF01809 DUF37, Domain of unknown function DUF37 , score 122.8, E-value 4.2e-34 272560000387 membrane protein insertase; Provisional; Region: PRK01318 272560000388 YidC periplasmic domain; Region: YidC_periplas; pfam14849 272560000389 membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592 272560000390 4 probable transmembrane helices predicted for BPSL0078 by TMHMM2.0 at aa 7-24, 368-390, 434-456 and 510-532 272560000391 Pfam match to entry PF02096 60KD_IMP, 60Kd inner membrane protein , score 362.6, E-value 2.6e-106 272560000392 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560000393 sequence-specific DNA binding site [nucleotide binding]; other site 272560000394 salt bridge; other site 272560000395 tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291 272560000396 GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396 272560000397 trmE is a tRNA modification GTPase; Region: trmE; cd04164 272560000398 G1 box; other site 272560000399 GTP/Mg2+ binding site [chemical binding]; other site 272560000400 Switch I region; other site 272560000401 G2 box; other site 272560000402 Switch II region; other site 272560000403 G3 box; other site 272560000404 G4 box; other site 272560000405 G5 box; other site 272560000406 Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631 272560000407 Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function , score 12.8, E-value 1.5e-08 272560000408 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000409 Genomic island GI 1 272560000410 integrase; Provisional; Region: PRK09692 272560000411 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 272560000412 active site 272560000413 Int/Topo IB signature motif; other site 272560000414 Region with similarity of part of (BPSS0378 to BPSS0382) Genomic island GI 13 272560000415 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 79.6, E-value 4.1e-21 272560000416 Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707 272560000417 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643 272560000418 Domain of unknown function (DUF927); Region: DUF927; pfam06048 272560000419 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000420 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000421 CotH protein; Region: CotH; cl19892 272560000422 Predicted helix-turn-helix motif with score 1073.000, SD 2.84 at aa 144-165, sequence NVCSDIAARFGVTADHVRKLKR 272560000423 Predicted nucleotidyltransferase [General function prediction only]; Region: COG4849 272560000424 Uncharacterized protein conserved in bacteria (DUF2186); Region: DUF2186; pfam09952 272560000425 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 272560000426 HTH-like domain; Region: HTH_21; pfam13276 272560000427 Integrase core domain; Region: rve; pfam00665 272560000428 Integrase core domain; Region: rve_3; pfam13683 272560000429 Pfam match to entry PF00665 rve, Integrase core domain , score 148.5, E-value 7.5e-42 272560000430 Transposase; Region: HTH_Tnp_1; pfam01527 272560000431 Pfam match to entry PF01527 Transposase_8, Transposase , score 134.4, E-value 1.3e-37 272560000432 Signal peptide predicted for BPSL0092 by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.435 between residues 37 and 38; signal peptide 272560000433 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 272560000434 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000435 Signal peptide predicted for BPSL0093 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.369 between residues 24 and 25; signal peptide 272560000436 Domain of unknown function (DUF4382); Region: DUF4382; pfam14321 272560000437 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000438 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000439 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560000440 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560000441 Coenzyme A binding pocket [chemical binding]; other site 272560000442 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 78.6, E-value 8.6e-21 272560000443 Signal peptide predicted for BPSL0097 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.808 between residues 22 and 23; signal peptide 272560000444 YaeQ protein; Region: YaeQ; pfam07152 272560000445 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253 272560000446 dimer interface [polypeptide binding]; other site 272560000447 metal binding site [ion binding]; metal-binding site 272560000448 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 42.7, E-value 5.5e-10 272560000449 bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435 272560000450 Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805 272560000451 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000452 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870 272560000453 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 272560000454 DNA binding site [nucleotide binding] 272560000455 active site 272560000456 Pfam match to entry PF02805 Ada_Zn_binding, Metal binding domain of Ada , score 124.5, E-value 1.3e-34 272560000457 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 47.8, E-value 1.6e-11 272560000458 Predicted helix-turn-helix motif with score 1765.000, SD 5.20 at aa 99-120, sequence FTLAQLSDAVHVSPFHLQRLFK 272560000459 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 23.9, E-value 0.00024 272560000460 Pfam match to entry PF02870 Methyltransf_1N, 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain , score 31.5, E-value 1.3e-06 272560000461 Pfam match to entry PF01035 Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain , score 165.4, E-value 6.3e-47 272560000462 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 272560000463 AlkA N-terminal domain; Region: AlkA_N; pfam06029 272560000464 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122 272560000465 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 272560000466 minor groove reading motif; other site 272560000467 helix-hairpin-helix signature motif; other site 272560000468 substrate binding pocket [chemical binding]; other site 272560000469 active site 272560000470 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein , score -22.8, E-value 0.00028 272560000471 glutamate--cysteine ligase; Provisional; Region: PRK02107 272560000472 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 272560000473 RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393 272560000474 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560000475 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 272560000476 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560000477 DNA binding residues [nucleotide binding] 272560000478 PS00716 Sigma-70 factors family signature 2. 272560000479 Predicted helix-turn-helix motif with score 2239.000, SD 6.81 at aa 438-459, sequence WSYEQIAARAGVSREQVRRIEK 272560000480 PS00715 Sigma-70 factors family signature 1. 272560000481 Pfam match to entry PF00140 sigma70_r1_2, Sigma-70 factor, region 1.2 , score 31.1, E-value 1.7e-06 272560000482 Signal peptide predicted for BPSL0106 by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.632 between residues 29 and 30; signal peptide 272560000483 CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482 272560000484 dimer interface [polypeptide binding]; other site 272560000485 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560000486 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560000487 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560000488 putative effector binding pocket; other site 272560000489 dimerization interface [polypeptide binding]; other site 272560000490 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 160.9, E-value 1.4e-45 272560000491 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 75.2, E-value 8.8e-20 272560000492 Predicted helix-turn-helix motif with score 1402.000, SD 3.96 at aa 20-41, sequence GSLSQAARRLAKTPSAVTKAIA 272560000493 Signal peptide predicted for BPSL0108 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.855 between residues 21 and 22; signal peptide 272560000494 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 272560000495 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000496 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 77.3, E-value 2e-20 272560000497 Arginase-like and histone-like hydrolases; Region: Arginase_HDAC; cl17011 272560000498 active site 272560000499 metal binding site [ion binding]; metal-binding site 272560000500 Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase , score 328.0, E-value 7e-96 272560000501 N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573 272560000502 putative active site; other site 272560000503 catalytic triad [active] 272560000504 putative dimer interface [polypeptide binding]; other site 272560000505 Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase , score 274.8, E-value 7.4e-80 272560000506 Weakly similar to the N-terminal regions of Streptomyces avermitilis hypothetical protein SWALL:Q82F88 (EMBL:AP005038) (164 aa) fasta scores: E(): 2.1, 33.33% id in 96 aa, and Streptomyces coelicolor transcriptional regulator SC4C6.04 SWALL:Q9XAN6 (EMBL:AL939128) (204 aa) fasta scores: E(): 5.2, 35% id in 80 aa. CDS contains a frameshift after codon 77;conserved hypothetical protein (fragment) 272560000507 portal vertex protein; Provisional; Region: Q; PHA02536 272560000508 2 probable transmembrane helices predicted for BPSL0112 by TMHMM2.0 at aa 7-29 and 61-83 272560000509 Protein of unknown function (DUF2778); Region: DUF2778; pfam10908 272560000510 SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195 272560000511 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560000512 CoenzymeA binding site [chemical binding]; other site 272560000513 subunit interaction site [polypeptide binding]; other site 272560000514 PHB binding site; other site 272560000515 Thioesterase-like superfamily; Region: 4HBT_3; pfam13622 272560000516 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 29.1, E-value 4.5e-08 272560000517 Patatin-like phospholipase; Region: Patatin; pfam01734 272560000518 active site 272560000519 nucleophile elbow; other site 272560000520 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 6.0, E-value 6.6e-06 272560000521 Putative D-3-Phosphoglycerate Dehydrogenases; Region: PGDH_like_1; cd12169 272560000522 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 272560000523 dimerization interface [polypeptide binding]; other site 272560000524 NAD binding site [chemical binding]; other site 272560000525 ligand binding site [chemical binding]; other site 272560000526 catalytic site [active] 272560000527 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 114.8, E-value 1e-31 272560000528 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 38.9, E-value 7.4e-09 272560000529 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560000530 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560000531 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560000532 putative effector binding pocket; other site 272560000533 dimerization interface [polypeptide binding]; other site 272560000534 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 80.6, E-value 2.1e-21 272560000535 PS00044 Bacterial regulatory proteins, lysR family signature. 272560000536 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 189.6, E-value 3.2e-54 272560000537 DNA topoisomerase III; Validated; Region: PRK08173 272560000538 TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362 272560000539 active site 272560000540 putative interdomain interaction site [polypeptide binding]; other site 272560000541 putative metal-binding site [ion binding]; other site 272560000542 putative nucleotide binding site [chemical binding]; other site 272560000543 DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186 272560000544 domain I; other site 272560000545 DNA binding groove [nucleotide binding] 272560000546 phosphate binding site [ion binding]; other site 272560000547 domain II; other site 272560000548 domain III; other site 272560000549 nucleotide binding site [chemical binding]; other site 272560000550 catalytic site [active] 272560000551 domain IV; other site 272560000552 C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342 272560000553 C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342 272560000554 Pfam match to entry PF01131 Topoisom_bac, DNA topoisomerase , score 347.9, E-value 7.4e-102 272560000555 PS00396 Prokaryotic DNA topoisomerase I active site. 272560000556 Pfam match to entry PF01751 Toprim, Toprim domain , score 67.6, E-value 1.8e-17 272560000557 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 272560000558 catalytic residues [active] 272560000559 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758 272560000560 Signal peptide predicted for BPSL0120 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.446 between residues 25 and 26; signal peptide 272560000561 DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481 272560000562 Pfam match to entry PF02481 SMF, SMF family , score 311.0, E-value 9e-91 272560000563 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 272560000564 active site 272560000565 catalytic residues [active] 272560000566 metal binding site [ion binding]; metal-binding site 272560000567 Pfam match to entry PF01327 Pep_deformylase, Polypeptide deformylase , score 251.2, E-value 9.5e-73 272560000568 methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005 272560000569 Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646 272560000570 putative active site [active] 272560000571 substrate binding site [chemical binding]; other site 272560000572 putative cosubstrate binding site; other site 272560000573 catalytic site [active] 272560000574 C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704 272560000575 substrate binding site [chemical binding]; other site 272560000576 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 183.6, E-value 2.1e-52 272560000577 Pfam match to entry PF02911 formyl_trans_C, Formyl transferase, C-terminal domain , score 108.9, E-value 6.2e-30 272560000578 Signal peptide predicted for BPSL0123 by SignalP 2.0 HMM (Signal peptide probabilty 0.784) with cleavage site probability 0.761 between residues 26 and 27; signal peptide 272560000579 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560000580 5 probable transmembrane helices predicted for BPSL0123 by TMHMM2.0 at aa 10-32, 45-67, 72-94, 115-137 and 152-174 272560000581 Pfam match to entry PF01810 LysE, LysE type translocator , score 93.1, E-value 3.6e-25 272560000582 M48 family peptidase; Provisional; Region: PRK03001 272560000583 4 probable transmembrane helices predicted for BPSL0124 by TMHMM2.0 at aa 7-29, 33-52, 145-167 and 177-196 272560000584 Pfam match to entry PF01435 Peptidase_M48, Peptidase M48 , score 105.0, E-value 9.6e-29 272560000585 16S rRNA methyltransferase B; Provisional; Region: PRK10901 272560000586 RNA binding domain of NusB (N protein-Utilization Substance B) and Sun (also known as RrmB or Fmu) proteins. This family includes two orthologous groups exemplified by the transcription termination factor NusB and the N-terminal domain of the...; Region: NusB_Sun; cl00223 272560000587 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560000588 S-adenosylmethionine binding site [chemical binding]; other site 272560000589 Pfam match to entry PF01189 Nol1_Nop2_Sun, NOL1/NOP2/sun family , score 218.3, E-value 7.4e-63 272560000590 PS01153 NOL1/NOP2/sun family signature. 272560000591 Signal peptide predicted for BPSL0126 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.616 between residues 31 and 32; signal peptide 272560000592 Domain of unknown function (DUF4390); Region: DUF4390; pfam14334 272560000593 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms]; Region: NtrY; COG5000 272560000594 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560000595 dimerization interface [polypeptide binding]; other site 272560000596 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560000597 putative active site [active] 272560000598 heme pocket [chemical binding]; other site 272560000599 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560000600 dimer interface [polypeptide binding]; other site 272560000601 phosphorylation site [posttranslational modification] 272560000602 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560000603 ATP binding site [chemical binding]; other site 272560000604 Mg2+ binding site [ion binding]; other site 272560000605 G-X-G motif; other site 272560000606 5 probable transmembrane helices predicted for BPSL0127 by TMHMM2.0 at aa 12-34, 49-71, 84-106, 121-138 and 311-333 272560000607 Pfam match to entry PF00672 HAMP, HAMP domain , score 65.0, E-value 1e-16 272560000608 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 42.9, E-value 4.8e-10 272560000609 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 98.0, E-value 1.2e-26 272560000610 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560000611 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560000612 active site 272560000613 phosphorylation site [posttranslational modification] 272560000614 intermolecular recognition site; other site 272560000615 dimerization interface [polypeptide binding]; other site 272560000616 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 272560000617 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 121.4, E-value 1.1e-33 272560000618 Predicted helix-turn-helix motif with score 1577.000, SD 4.56 at aa 191-212, sequence GSMTRVAEKTGLERTHLYRKLK 272560000619 integrase; Provisional; Region: int; PHA02601 272560000620 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560000621 active site 272560000622 DNA binding site [nucleotide binding] 272560000623 Int/Topo IB signature motif; other site 272560000624 Genomic island GI 2; Prophage phiK96243. Sponaneously excisable, induced by UV 272560000625 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 91.4, E-value 1.2e-24 272560000626 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain , score -6.0, E-value 0.15 272560000627 DNA primase domain-containing protein; Region: PHA02415 272560000628 CHC2 zinc finger; Region: zf-CHC2; cl17510 272560000629 Toprim domain; Region: Toprim_3; pfam13362 272560000630 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000631 Choline sulfatase enzyme C terminal; Region: Choline_sulf_C; pfam12411 272560000632 Signal peptide predicted for BPSL0134 by SignalP 2.0 HMM (Signal peptide probabilty 0.908) with cleavage site probability 0.520 between residues 31 and 32; signal peptide 272560000633 2 probable transmembrane helices predicted for BPSL0134 by TMHMM2.0 at aa 9-31 and 44-66 272560000634 BRO family, N-terminal domain; Region: Bro-N; smart01040 272560000635 Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606 272560000636 Predicted helix-turn-helix motif with score 1012.000, SD 2.63 at aa 18-39, sequence PKRQDVQQALGWDDSQVSRFLS 272560000637 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560000638 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560000639 non-specific DNA binding site [nucleotide binding]; other site 272560000640 salt bridge; other site 272560000641 sequence-specific DNA binding site [nucleotide binding]; other site 272560000642 Predicted helix-turn-helix motif with score 1033.000, SD 2.71 at aa 32-53, sequence LSQRAFAERGGVTEKTQVLYEK 272560000643 1 probable transmembrane helix predicted for BPSL0142 by TMHMM2.0 at aa 170-187 272560000644 BRCT domain type II [General function prediction only]; Region: COG5275 272560000645 tail protein; Provisional; Region: D; PHA02561 272560000646 Region with similarity to part of Genomic island GI 15 (BPSS1089 to BPSS1160) 272560000647 Phage P2 GpU; Region: Phage_P2_GpU; pfam06995 272560000648 Phage-related tail protein [Function unknown]; Region: COG5283 272560000649 7 probable transmembrane helices predicted for BPSL0146 by TMHMM2.0 at aa 567-589, 604-623, 635-657, 667-689, 702-724, 751-773 and 780-802 272560000650 Phage P2 GpE; Region: Phage_P2_GpE; pfam06528 272560000651 Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109 272560000652 major tail tube protein; Provisional; Region: FII; PHA02600 272560000653 major tail sheath protein; Provisional; Region: FI; PHA02560 272560000654 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 272560000655 Phage Tail Collar Domain; Region: Collar; pfam07484 272560000656 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684 272560000657 baseplate assembly protein; Provisional; Region: J; PHA02568 272560000658 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 272560000659 Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540 272560000660 DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863 272560000661 PS00092 N-6 Adenine-specific DNA methylases signature. 272560000662 Pfam match to entry PF01555 N6_N4_Mtase, DNA methylase , score 36.1, E-value 5.4e-08 272560000663 Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069 272560000664 P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891 272560000665 Signal peptide predicted for BPSL0160 by SignalP 2.0 HMM (Signal peptide probabilty 0.983) with cleavage site probability 0.798 between residues 20 and 21; signal peptide 272560000666 Signal peptide predicted for BPSL0162 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.515 between residues 29 and 30; signal peptide 272560000667 phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495 272560000668 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560000669 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 272560000670 Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409 272560000671 Protein of unknown function (DUF3380); Region: DUF3380; pfam11860 272560000672 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain , score 49.5, E-value 5e-12 272560000673 Protein of unknown function (DUF754); Region: DUF754; pfam05449 272560000674 3 probable transmembrane helices predicted for BPSL0164 by TMHMM2.0 at aa 4-23, 32-54 and 59-76 272560000675 Signal peptide predicted for BPSL0165 by SignalP 2.0 HMM (Signal peptide probabilty 0.964) with cleavage site probability 0.544 between residues 24 and 25; signal peptide 272560000676 3 probable transmembrane helices predicted for BPSL0165 by TMHMM2.0 at aa 20-42, 54-76 and 81-98 272560000677 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 272560000678 hypothetical protein; Region: PHA02417 272560000679 Signal peptide predicted for BPSL0168 by SignalP 2.0 HMM (Signal peptide probabilty 0.886) with cleavage site probability 0.385 between residues 19 and 20; signal peptide 272560000680 Phage head completion protein (GPL); Region: Phage_GPL; pfam05926 272560000681 Signal peptide predicted for BPSL0169 by SignalP 2.0 HMM (Signal peptide probabilty 0.947) with cleavage site probability 0.448 between residues 29 and 30; signal peptide 272560000682 terminase endonuclease subunit; Provisional; Region: M; PHA02537 272560000683 capsid protein; Provisional; Region: N; PHA02538 272560000684 capsid-scaffolding protein; Provisional; Region: O; PHA02529 272560000685 terminase ATPase subunit; Provisional; Region: P; PHA02535 272560000686 Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056 272560000687 Phage Terminase; Region: Terminase_1; cl19862 272560000688 Predicted helix-turn-helix motif with score 1584.000, SD 4.58 at aa 26-47, sequence WRIASIARHLDIKPATVASWCR 272560000689 portal vertex protein; Provisional; Region: Q; PHA02536 272560000690 probable addiction module antidote protein; Region: dnstrm_HI1420; TIGR02684 272560000691 Predicted helix-turn-helix motif with score 1567.000, SD 4.52 at aa 48-69, sequence RGMTALARESGVKREALYRALS 272560000692 putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683 272560000693 2 probable transmembrane helices predicted for BPSL0176 by TMHMM2.0 at aa 69-91 and 189-211 272560000694 3-prime partial tRNA-Phe at end of prophage 272560000695 ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995 272560000696 Ligand Binding Site [chemical binding]; other site 272560000697 Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602 272560000698 4Fe-4S single cluster domain; Region: Fer4_14; pfam13394 272560000699 6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242 272560000700 active site 272560000701 Pfam match to entry PF01242 PTPS, 6-pyruvoyl tetrahydropterin synthase , score -7.8, E-value 4.7e-06 272560000702 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 272560000703 Pfam match to entry PF03328 HpcH_HpaI, HpcH/HpaI aldolase , score 334.0, E-value 1.1e-97 272560000704 Signal peptide predicted for BPSL0181 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.963 between residues 40 and 41; signal peptide 272560000705 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 272560000706 Sel1-like repeats; Region: SEL1; smart00671 272560000707 Sel1-like repeats; Region: SEL1; smart00671 272560000708 Sel1-like repeats; Region: SEL1; smart00671 272560000709 rod shape-determining protein RodA; Region: rodA_shape; TIGR02210 272560000710 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein , score 418.8, E-value 3.2e-123 272560000711 8 probable transmembrane helices predicted for BPSL0182 by TMHMM2.0 at aa 21-43, 73-95, 135-157, 162-181, 186-203, 286-308, 315-337 and 352-374 272560000712 PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 272560000713 penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423 272560000714 Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717 272560000715 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 272560000716 PS00583 pfkB family of carbohydrate kinases signature 1. 272560000717 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 281.2, E-value 8.9e-82 272560000718 Pfam match to entry PF03717 PBP_dimer, Penicillin-binding Protein dimerisation domain , score 164.4, E-value 1.2e-46 272560000719 1 probable transmembrane helix predicted for BPSL0183 by TMHMM2.0 at aa 20-42 272560000720 Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreD; COG2891 272560000721 3 probable transmembrane helices predicted for BPSL0184 by TMHMM2.0 at aa 13-35, 55-77 and 97-119 272560000722 rod shape-determining protein MreC; Provisional; Region: PRK13922 272560000723 1 probable transmembrane helix predicted for BPSL0185 by TMHMM2.0 at aa 15-32 272560000724 rod shape-determining protein MreB; Provisional; Region: PRK13927 272560000725 MreB and similar proteins; Region: MreB_like; cd10225 272560000726 nucleotide binding site [chemical binding]; other site 272560000727 Mg binding site [ion binding]; other site 272560000728 putative protofilament interaction site [polypeptide binding]; other site 272560000729 RodZ interaction site [polypeptide binding]; other site 272560000730 aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034 272560000731 aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012 272560000732 Pfam match to entry PF01425 Amidase, Amidase , score 642.3, E-value 1.8e-190 272560000733 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000734 PS00571 Amidases signature. 272560000735 aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477 272560000736 GatB/GatE catalytic domain; Region: GatB_N; pfam02934 272560000737 GatB domain; Region: GatB_Yqey; smart00845 272560000738 Pfam match to entry PF02934 GatB_N, PET112 family, N terminal region , score 502.1, E-value 2.7e-148 272560000739 PS01234 PET112 family signature. 272560000740 Pfam match to entry PF01162 GatB, PET112 family, C terminal region , score 122.7, E-value 4.3e-34 272560000741 Pfam match to entry PF02637 DUF186, GatB/Yqey domain , score 207.4, E-value 1.4e-59 272560000742 Polyphosphate kinase 2 (PPK2); Region: PPK2; cl11971 272560000743 Pfam match to entry PF03976 DUF344, Domain of unknown function (DUF344) , score 276.1, E-value 3e-80 272560000744 Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Nape_like_AP-endo; cd10281 272560000745 putative active site [active] 272560000746 putative catalytic site [active] 272560000747 putative DNA binding site [nucleotide binding]; other site 272560000748 putative phosphate binding site [ion binding]; other site 272560000749 metal binding site A [ion binding]; metal-binding site 272560000750 putative AP binding site [nucleotide binding]; other site 272560000751 putative metal binding site B [ion binding]; other site 272560000752 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 170.8, E-value 1.5e-48 272560000753 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 272560000754 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283 272560000755 putative NAD(P) binding site [chemical binding]; other site 272560000756 putative substrate binding site [chemical binding]; other site 272560000757 catalytic Zn binding site [ion binding]; other site 272560000758 structural Zn binding site [ion binding]; other site 272560000759 dimer interface [polypeptide binding]; other site 272560000760 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 341.3, E-value 6.8e-100 272560000761 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560000762 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560000763 PS00190 Cytochrome c family heme-binding site signature. 272560000764 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 272560000765 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000766 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560000767 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560000768 PS00041 Bacterial regulatory proteins, araC family signature. 272560000769 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 35.2, E-value 1e-07 272560000770 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 26.3, E-value 4.6e-05 272560000771 Peptidase family M48; Region: Peptidase_M48; cl12018 272560000772 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560000773 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560000774 putative substrate translocation pore; other site 272560000775 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560000776 10 probable transmembrane helices predicted for BPSL0195 by TMHMM2.0 at aa 31-53, 63-80, 100-119, 124-146, 244-266, 281-303, 310-329, 339-361, 373-395 and 400-419 272560000777 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560000778 S-adenosylmethionine binding site [chemical binding]; other site 272560000779 homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175 272560000780 homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392 272560000781 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 44.4, E-value 1.7e-10 272560000782 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560000783 division inhibitor protein; Provisional; Region: slmA; PRK09480 272560000784 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560000785 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 33.2, E-value 3.8e-07 272560000786 Predicted helix-turn-helix motif with score 1894.000, SD 5.64 at aa 54-75, sequence ITTAALAARLDVSEAALYRHFS 272560000787 haloacid dehalogenase-like hydrolase; Region: HAD; cl19137 272560000788 Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419 272560000789 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 30.4, E-value 2.7e-06 272560000790 AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250 272560000791 feedback inhibition sensing region; other site 272560000792 homohexameric interface [polypeptide binding]; other site 272560000793 nucleotide binding site [chemical binding]; other site 272560000794 N-acetyl-L-glutamate binding site [chemical binding]; other site 272560000795 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 166.0, E-value 4.1e-47 272560000796 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560000797 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560000798 dimer interface [polypeptide binding]; other site 272560000799 phosphorylation site [posttranslational modification] 272560000800 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560000801 ATP binding site [chemical binding]; other site 272560000802 Mg2+ binding site [ion binding]; other site 272560000803 G-X-G motif; other site 272560000804 5 probable transmembrane helices predicted for BPSL0201 by TMHMM2.0 at aa 16-38, 43-65, 72-94, 114-136 and 156-173 272560000805 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 28.9, E-value 7.6e-06 272560000806 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 85.7, E-value 6e-23 272560000807 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain [Signal transduction mechanisms / Transcription]; Region: COG4567 272560000808 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560000809 active site 272560000810 phosphorylation site [posttranslational modification] 272560000811 intermolecular recognition site; other site 272560000812 dimerization interface [polypeptide binding]; other site 272560000813 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560000814 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 84.8, E-value 1.2e-22 272560000815 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 41.9, E-value 9.1e-10 272560000816 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 156-177, sequence NNISATARALNMHRRTLQRKLA 272560000817 ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201 272560000818 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560000819 Walker A motif; other site 272560000820 ATP binding site [chemical binding]; other site 272560000821 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560000822 Walker B motif; other site 272560000823 arginine finger; other site 272560000824 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 272560000825 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 26.6, E-value 6.3e-07 272560000826 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000827 Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913 272560000828 active site 272560000829 HslU subunit interaction site [polypeptide binding]; other site 272560000830 RNA polymerase-binding protein DksA; Region: dksA; TIGR02420 272560000831 Pfam match to entry PF01258 zf_dskA_traR, Prokaryotic dksA/traR C4-type zinc finger , score 53.2, E-value 3.7e-13 272560000832 Putative GTPases (G3E family) [General function prediction only]; Region: COG0523 272560000833 The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112 272560000834 P-loop, Walker A motif; other site 272560000835 Base recognition motif; other site 272560000836 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 272560000837 Pfam match to entry PF02492 cobW, Cobalamin synthesis protein/P47K , score 479.6, E-value 1.7e-141 272560000838 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000839 Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092 272560000840 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359 272560000841 Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572 272560000842 putative RNA binding site [nucleotide binding]; other site 272560000843 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560000844 S-adenosylmethionine binding site [chemical binding]; other site 272560000845 site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236 272560000846 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560000847 active site 272560000848 DNA binding site [nucleotide binding] 272560000849 Int/Topo IB signature motif; other site 272560000850 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 142.6, E-value 4.5e-40 272560000851 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain , score 61.9, E-value 9.1e-16 272560000852 Protein of unknown function, DUF484; Region: DUF484; cl17449 272560000853 diaminopimelate epimerase; Provisional; Region: dapF; PRK00450 272560000854 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 272560000855 Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678 272560000856 Pfam match to entry PF01678 DAP_epimerase, Diaminopimelate epimerase , score 127.8, E-value 1.3e-35 272560000857 Pfam match to entry PF01678 DAP_epimerase, Diaminopimelate epimerase , score 164.2, E-value 1.4e-46 272560000858 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984 272560000859 putative acyl-acceptor binding pocket; other site 272560000860 Pfam match to entry PF03279 Lip_A_acyltrans, Bacterial lipid A biosynthesis acyltransferase , score 141.8, E-value 8.1e-40 272560000861 S-adenosylmethionine synthetase; Validated; Region: PRK05250 272560000862 S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438 272560000863 S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772 272560000864 S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773 272560000865 Pfam match to entry PF00438 S-AdoMet_synt, S-adenosylmethionine synthetase, N-terminal domain , score 180.7, E-value 1.6e-51 272560000866 Pfam match to entry PF02772 S-AdoMet_syntD2, S-adenosylmethionine synthetase, central domain , score 254.9, E-value 7.4e-74 272560000867 PS00376 S-adenosylmethionine synthetase signature 1. 272560000868 Pfam match to entry PF02773 S-AdoMet_syntD3, S-adenosylmethionine synthetase, C-terminal domain , score 301.2, E-value 8.1e-88 272560000869 PS00377 S-adenosylmethionine synthetase signature 2. 272560000870 phosphoribosylformylglycinamidine synthase, single chain form; Region: FGAM_synt; TIGR01735 272560000871 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 272560000872 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 272560000873 voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293 272560000874 active site 272560000875 catalytic tetrad [active] 272560000876 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase , score 256.2, E-value 2.8e-74 272560000877 2 probable transmembrane helices predicted for BPSL0216 by TMHMM2.0 at aa 5-27 and 40-59 272560000878 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560000879 EamA-like transporter family; Region: EamA; pfam00892 272560000880 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 60.0, E-value 3.4e-15 272560000881 10 probable transmembrane helices predicted for BPSL0217 by TMHMM2.0 at aa 21-43, 53-73, 86-105, 109-131, 138-157, 161-183, 190-212, 222-244, 251-273 and 277-296 272560000882 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 38.9, E-value 7.6e-09 272560000883 Signal peptide predicted for BPSL0218 by SignalP 2.0 HMM (Signal peptide probabilty 0.805) with cleavage site probability 0.785 between residues 21 and 22; signal peptide 272560000884 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560000885 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560000886 putative substrate translocation pore; other site 272560000887 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -62.5, E-value 1.3e-05 272560000888 12 probable transmembrane helices predicted for BPSL0218 by TMHMM2.0 at aa 40-62, 82-101, 114-131, 135-157, 164-186, 196-218, 249-271, 281-303, 310-332, 337-359, 372-394 and 398-420 272560000889 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025 272560000890 serine/threonine protein kinase; Provisional; Region: PRK11768 272560000891 Phosphotransferase enzyme family; Region: APH; pfam01636 272560000892 Probable gene remnant. Similar to the C-terminal regions of Ralstonia solanacearum probable transcription regulator protein rsp0823 or rs05372 SWALL:Q8XRK8 (EMBL:AL646081) (335 aa) fasta scores: E(): 1.2e-06, 63.33% id in 60 aa, and Xanthomonas campestris transcriptional regulator XCC3246 SWALL:AAM42516 (EMBL:AE012442) (289 aa) fasta scores: E(): 1.3, 42.25% id in 71 aa;conserved hypothetical protein (fragment) 272560000893 Coniferyl aldehyde dehydrogenase-like; Region: ALDH_CALDH_CalB; cd07133 272560000894 NAD(P) binding site [chemical binding]; other site 272560000895 catalytic residues [active] 272560000896 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 386.2, E-value 2.2e-113 272560000897 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560000898 isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561 272560000899 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560000900 active site 272560000901 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 166.0, E-value 4.1e-47 272560000902 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 88.8, E-value 7.4e-24 272560000903 PS00072 Acyl-CoA dehydrogenases signature 1. 272560000904 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 12.0, E-value 8.3e-05 272560000905 choline dehydrogenase; Validated; Region: PRK02106 272560000906 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560000907 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560000908 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score 668.5, E-value 2.2e-198 272560000909 PS00623 GMC oxidoreductases signature 1. 272560000910 PS00624 GMC oxidoreductases signature 2. 272560000911 Signal peptide predicted for BPSL0225 by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.310 between residues 29 and 30; signal peptide 272560000912 Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120 272560000913 Pfam match to entry PF02120 Flg_hook, Flagellar hook-length control protein , score 69.4, E-value 2.6e-19 272560000914 flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689 272560000915 Pfam match to entry PF02050 FliJ, Flagellar FliJ protein , score 40.0, E-value 3.4e-09 272560000916 flagellar protein export ATPase FliI; Region: FliI_clade1; TIGR03496 272560000917 Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136 272560000918 Walker A motif/ATP binding site; other site 272560000919 Walker B motif; other site 272560000920 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 471.3, E-value 5e-139 272560000921 PS00152 ATP synthase alpha and beta subunits signature. 272560000922 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000923 flagellar assembly protein H; Validated; Region: fliH; PRK05687 272560000924 Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811 272560000925 Flagellar assembly protein FliH; Region: FliH; pfam02108 272560000926 Pfam match to entry PF02108 FliH, Flagellar assembly protein FliH , score 53.2, E-value 3.8e-13 272560000927 flagellar motor switch protein G; Validated; Region: fliG; PRK05686 272560000928 FliG N-terminal domain; Region: FliG_N; pfam14842 272560000929 FliG middle domain; Region: FliG_M; pfam14841 272560000930 FliG C-terminal domain; Region: FliG_C; pfam01706 272560000931 Pfam match to entry PF01706 FliG-C, FliG C-terminal domain , score 194.3, E-value 1.3e-55 272560000932 flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007 272560000933 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514 272560000934 Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345 272560000935 Pfam match to entry PF01514 YscJ_FliF, Secretory protein of YscJ/FliF family , score 279.8, E-value 2.2e-81 272560000936 1 probable transmembrane helix predicted for BPSL0230 by TMHMM2.0 at aa 62-81 272560000937 Signal peptide predicted for BPSL0231 by SignalP 2.0 HMM (Signal peptide probabilty 0.867) with cleavage site probability 0.466 between residues 22 and 23; signal peptide 272560000938 Flagellar hook-basal body complex protein FliE; Region: FliE; cl09139 272560000939 Pfam match to entry PF02049 FliE, Flagellar hook-basal body complex protein FliE , score 84.6, E-value 1.3e-22 272560000940 flagellar protein FliS; Validated; Region: fliS; PRK05685 272560000941 Pfam match to entry PF02561 FliS, Flagellar protein FliS , score 97.8, E-value 1.4e-26 272560000942 Flagellar protein FliT; Region: FliT; pfam05400 272560000943 Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120 272560000944 PS00138 Serine proteases, subtilase, serine active site. 272560000945 FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167 272560000946 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family , score 35.8, E-value 1.2e-10 272560000947 PepSY-associated TM helix; Region: PepSY_TM_1; cl19400 272560000948 3 probable transmembrane helices predicted for BPSL0236 by TMHMM2.0 at aa 57-79, 199-221 and 230-247 272560000949 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975 272560000950 XdhC and CoxI family; Region: XdhC_CoxI; pfam02625 272560000951 XdhC Rossmann domain; Region: XdhC_C; pfam13478 272560000952 Pfam match to entry PF02625 DUF182, Uncharacterized BCR, COG1975 , score 99.5, E-value 4.4e-27 272560000953 amino acid transporter; Region: 2A0306; TIGR00909 272560000954 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560000955 C-terminus of AA_permease; Region: AA_permease_C; pfam13906 272560000956 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -42.4, E-value 8.4e-10 272560000957 12 probable transmembrane helices predicted for BPSL0238 by TMHMM2.0 at aa 30-52, 57-76, 83-105, 154-176, 183-205, 220-242, 255-277, 301-323, 349-371, 375-397, 410-429 and 434-453 272560000958 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560000959 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560000960 active site 272560000961 phosphorylation site [posttranslational modification] 272560000962 intermolecular recognition site; other site 272560000963 dimerization interface [polypeptide binding]; other site 272560000964 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560000965 DNA binding residues [nucleotide binding] 272560000966 dimerization interface [polypeptide binding]; other site 272560000967 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 60.5, E-value 2.4e-15 272560000968 Predicted helix-turn-helix motif with score 1402.000, SD 3.96 at aa 165-186, sequence KRLTDIAHALSLSVKTVSVYRT 272560000969 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 141.2, E-value 1.2e-39 272560000970 Possible gene remnant. Two-component regulatory system family, sensor kinase. Similar to the C-terminal regions of Streptomyces coelicolor two component system histidine kinase SCO1369 or SC10A9.11 SWALL:Q9AK93 (EMBL:AL583943) (404 aa) fasta scores: E(): 8.6e-12, 33.33% id in 285 aa, and Deinococcus radiodurans sensor histidine kinase DR0577 SWALL:Q9RWT8 (EMBL:AE001916) (590 aa) fasta scores: E(): 1.1e-10, 34.69% id in 245 aa;sensor kinase (fragment) 272560000971 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 45.2, E-value 9.7e-11 272560000972 Signal peptide predicted for BPSL0240 by SignalP 2.0 HMM (Signal peptide probabilty 0.856) with cleavage site probability 0.512 between residues 22 and 23 272560000973 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 272560000974 Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195 272560000975 FAD binding pocket [chemical binding]; other site 272560000976 FAD binding motif [chemical binding]; other site 272560000977 phosphate binding motif [ion binding]; other site 272560000978 beta-alpha-beta structure motif; other site 272560000979 NAD binding pocket [chemical binding]; other site 272560000980 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560000981 Pfam match to entry PF01810 LysE, LysE type translocator , score 30.9, E-value 1.9e-06 272560000982 5 probable transmembrane helices predicted for BPSL0242 by TMHMM2.0 at aa 4-26, 38-60, 70-89, 129-151 and 161-183 272560000983 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 272560000984 putative catalytic site [active] 272560000985 putative metal binding site [ion binding]; other site 272560000986 putative phosphate binding site [ion binding]; other site 272560000987 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 44.7, E-value 1.4e-10 272560000988 Signal peptide predicted for BPSL0244 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.867 between residues 38 and 39; signal peptide 272560000989 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560000990 Walker A motif; other site 272560000991 ATP binding site [chemical binding]; other site 272560000992 Walker B motif; other site 272560000993 arginine finger; other site 272560000994 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 53.0, E-value 4.3e-13 272560000995 PS00017 ATP/GTP-binding site motif A (P-loop). 272560000996 hydroxyglutarate oxidase; Provisional; Region: PRK11728; cl19156 272560000997 FAD dependent oxidoreductase; Region: DAO; pfam01266 272560000998 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -36.9, E-value 5.7e-06 272560000999 Signal peptide predicted for BPSL0247 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.956 between residues 33 and 34; signal peptide 272560001000 High potential iron-sulfur protein; Region: HIPIP; pfam01355 272560001001 Pfam match to entry PF01355 HIPIP, High potential iron-sulfur protein , score 94.6, E-value 1.3e-25 272560001002 PS00596 High potential iron-sulfur proteins signature. 272560001003 citrate-proton symporter; Provisional; Region: PRK15075 272560001004 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560001005 putative substrate translocation pore; other site 272560001006 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 153.8, E-value 1.9e-43 272560001007 12 probable transmembrane helices predicted for BPSL0248 by TMHMM2.0 at aa 21-43, 58-80, 92-114, 129-151, 158-180, 190-210, 242-264, 279-301, 308-328, 338-360, 373-395 and 405-422 272560001008 PS00217 Sugar transport proteins signature 2. 272560001009 PS00216 Sugar transport proteins signature 1. 272560001010 Signal peptide predicted for BPSL0249 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 39 and 40; signal peptide 272560001011 antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109 272560001012 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 272560001013 peptide binding site [polypeptide binding]; other site 272560001014 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 646.0, E-value 1.3e-191 272560001015 PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 272560001016 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 272560001017 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560001018 dimer interface [polypeptide binding]; other site 272560001019 conserved gate region; other site 272560001020 putative PBP binding loops; other site 272560001021 ABC-ATPase subunit interface; other site 272560001022 6 probable transmembrane helices predicted for BPSL0250 by TMHMM2.0 at aa 9-31, 100-122, 143-165, 195-217, 256-278 and 306-328 272560001023 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 30.2, E-value 3.1e-06 272560001024 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560001025 dipeptide transporter; Provisional; Region: PRK10913 272560001026 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560001027 dimer interface [polypeptide binding]; other site 272560001028 conserved gate region; other site 272560001029 putative PBP binding loops; other site 272560001030 ABC-ATPase subunit interface; other site 272560001031 5 probable transmembrane helices predicted for BPSL0251 by TMHMM2.0 at aa 42-64, 114-136, 151-173, 234-256 and 276-298 272560001032 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 38.6, E-value 9.6e-09 272560001033 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444 272560001034 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560001035 Walker A/P-loop; other site 272560001036 ATP binding site [chemical binding]; other site 272560001037 Q-loop/lid; other site 272560001038 ABC transporter signature motif; other site 272560001039 Walker B; other site 272560001040 D-loop; other site 272560001041 H-loop/switch region; other site 272560001042 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560001043 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 227.5, E-value 1.2e-65 272560001044 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001045 dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308 272560001046 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560001047 Walker A/P-loop; other site 272560001048 ATP binding site [chemical binding]; other site 272560001049 Q-loop/lid; other site 272560001050 ABC transporter signature motif; other site 272560001051 Walker B; other site 272560001052 D-loop; other site 272560001053 H-loop/switch region; other site 272560001054 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560001055 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 219.9, E-value 2.4e-63 272560001056 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001057 PS00211 ABC transporters family signature. 272560001058 Signal peptide predicted for BPSL0254 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.679 between residues 26 and 27; signal peptide 272560001059 TraB family; Region: TraB; pfam01963 272560001060 Protein of unknown function (DUF979); Region: DUF979; pfam06166 272560001061 9 probable transmembrane helices predicted for BPSL0255 by TMHMM2.0 at aa 5-25, 32-49, 54-76, 97-116, 131-150, 169-191, 211-233, 254-276 and 296-315 272560001062 Protein of unknown function (DUF969); Region: DUF969; pfam06149 272560001063 4 probable transmembrane helices predicted for BPSL0256 by TMHMM2.0 at aa 7-26, 61-78, 164-186 and 199-221 272560001064 Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800 272560001065 putative active site [active] 272560001066 Pfam match to entry PF03746 LamB_YcsF, LamB/YcsF family , score 483.4, E-value 1.2e-142 272560001067 Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984 272560001068 Pfam match to entry PF02626 DUF183, Uncharacterized ACR, COG1984 , score 358.2, E-value 5.7e-105 272560001069 Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049 272560001070 Pfam match to entry PF02682 DUF213, Uncharacterized ACR, COG2049 , score 314.6, E-value 7.8e-92 272560001071 MarR family; Region: MarR_2; cl17246 272560001072 5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727 272560001073 Pfam match to entry PF01812 5-FTHF_cyc-lig, 5-formyltetrahydrofolate cyclo-ligase , score 105.4, E-value 7.1e-29 272560001074 lytic murein transglycosylase; Provisional; Region: PRK11619 272560001075 Soluble lytic murein transglycosylase L domain; Region: SLT_L; pfam14718 272560001076 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560001077 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560001078 catalytic residue [active] 272560001079 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain , score 79.3, E-value 5.2e-21 272560001080 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs; Region: NDUFA9_like_SDR_a; cd05271 272560001081 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 272560001082 putative NAD(P) binding site [chemical binding]; other site 272560001083 active site 272560001084 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560001085 GST_N family, unknown subfamily 1; composed of uncharacterized proteins, predominantly from bacteria, with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with...; Region: GST_N_1; cd03043 272560001086 putative C-terminal domain interface [polypeptide binding]; other site 272560001087 putative GSH binding site (G-site) [chemical binding]; other site 272560001088 putative dimer interface [polypeptide binding]; other site 272560001089 C-terminal, alpha helical domain of an unknown subfamily 3 of Glutathione S-transferases; Region: GST_C_3; cd03194 272560001090 putative N-terminal domain interface [polypeptide binding]; other site 272560001091 putative dimer interface [polypeptide binding]; other site 272560001092 putative substrate binding pocket (H-site) [chemical binding]; other site 272560001093 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 34.1, E-value 2.1e-07 272560001094 multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885 272560001095 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 272560001096 active site 272560001097 NTP binding site [chemical binding]; other site 272560001098 metal binding triad [ion binding]; metal-binding site 272560001099 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 272560001100 CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cl17503 272560001101 Pfam match to entry PF01743 PolyA_pol, Poly A polymerase , score 154.3, E-value 1.4e-43 272560001102 Pfam match to entry PF01966 HD, HD domain , score 29.1, E-value 6.7e-06 272560001103 Killing trait; Region: RebB; pfam11747 272560001104 FlgN protein; Region: FlgN; pfam05130 272560001105 Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316 272560001106 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 272560001107 Pfam match to entry PF03240 FlgA, FlgA family , score 139.7, E-value 3.4e-39 272560001108 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001109 flagellar basal body rod protein FlgB; Provisional; Region: flgB; PRK12626 272560001110 flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680 272560001111 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 33.5, E-value 3.2e-07 272560001112 PS00588 Flagella basal body rod proteins signature. 272560001113 flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681 272560001114 flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173 272560001115 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 272560001116 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 52.3, E-value 7.2e-13 272560001117 PS00588 Flagella basal body rod proteins signature. 272560001118 flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655 272560001119 Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963 272560001120 FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861 272560001121 Pfam match to entry PF03963 FlgD, Flagellar hook capping protein , score 133.2, E-value 3e-37 272560001122 flagellar hook protein FlgE; Validated; Region: flgE; PRK05682 272560001123 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 272560001124 Flagellar basal body protein FlaE; Region: FlaE; pfam07559 272560001125 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 272560001126 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 41.2, E-value 1.5e-09 272560001127 PS00588 Flagella basal body rod proteins signature. 272560001128 flagellar basal body rod protein FlgF; Reviewed; Region: flgF; PRK12640 272560001129 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 272560001130 flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490 272560001131 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 44.6, E-value 1.5e-10 272560001132 PS00588 Flagella basal body rod proteins signature. 272560001133 flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12694 272560001134 Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460 272560001135 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 272560001136 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 59.1, E-value 6.4e-15 272560001137 PS00588 Flagella basal body rod proteins signature. 272560001138 Signal peptide predicted for BPSL0276 by SignalP 2.0 HMM (Signal peptide probabilty 0.978) with cleavage site probability 0.598 between residues 38 and 39; signal peptide 272560001139 flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK12697 272560001140 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001141 Pfam match to entry PF02107 FlgH, Flagellar L-ring protein , score 239.0, E-value 4.4e-69 272560001142 Signal peptide predicted for BPSL0277 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.399 between residues 40 and 41; signal peptide 272560001143 flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303 272560001144 Pfam match to entry PF02119 FlgI, Flagellar P-ring protein , score 634.3, E-value 4.4e-188 272560001145 flagellar rod assembly protein/muramidase FlgJ; Provisional; Region: flgJ; PRK12709 272560001146 Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951 272560001147 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361 272560001148 Pfam match to entry PF01832 Amidase_4, Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase , score 148.9, E-value 5.6e-42 272560001149 Flagellar regulator YcgR; Region: YcgR; pfam07317 272560001150 c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581 272560001151 PilZ domain; Region: PilZ; pfam07238 272560001152 Signal peptide predicted for BPSL0280 by SignalP 2.0 HMM (Signal peptide probabilty 0.732) with cleavage site probability 0.479 between residues 30 and 31; signal peptide 272560001153 flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK06945 272560001154 Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429 272560001155 Pfam match to entry PF00460 flg_bb_rod, Flagella basal body rod protein , score 22.4, E-value 3.3e-05 272560001156 flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08870 272560001157 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 272560001158 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus , score 45.2, E-value 9.8e-11 272560001159 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560001160 Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233 272560001161 Pfam match to entry PF00860 xan_ur_permease, Permease , score 388.3, E-value 5e-114 272560001162 11 probable transmembrane helices predicted for BPSL0282 by TMHMM2.0 at aa 120-142, 147-169, 179-201, 208-230, 240-257, 264-286, 310-332, 353-375, 390-412, 419-441 and 470-492 272560001163 PS01116 Xanthine/uracil permeases family signature. 272560001164 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560001165 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560001166 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560001167 dimerization interface [polypeptide binding]; other site 272560001168 substrate binding pocket [chemical binding]; other site 272560001169 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 147.9, E-value 1.1e-41 272560001170 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 94.5, E-value 1.3e-25 272560001171 PS00044 Bacterial regulatory proteins, lysR family signature. 272560001172 Predicted helix-turn-helix motif with score 1582.000, SD 4.58 at aa 21-42, sequence ESFSAAGEELHVTHGAISRQIA 272560001173 Chromate transporter; Region: Chromate_transp; pfam02417 272560001174 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 92.4, E-value 6.1e-25 272560001175 4 probable transmembrane helices predicted for BPSL0284 by TMHMM2.0 at aa 7-29, 73-95, 102-124 and 139-161 272560001176 Chromate transporter; Region: Chromate_transp; pfam02417 272560001177 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 45.8, E-value 6.4e-11 272560001178 5 probable transmembrane helices predicted for BPSL0285 by TMHMM2.0 at aa 5-27, 47-69, 76-98, 113-135 and 156-175 272560001179 PS01036 Heat shock hsp70 proteins family signature 3. 272560001180 1 probable transmembrane helix predicted for BPSL0286 by TMHMM2.0 at aa 7-26 272560001181 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824 272560001182 PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274 272560001183 PhnA protein; Region: PhnA; pfam03831 272560001184 Pfam match to entry PF03831 PhnA, PhnA protein , score 109.6, E-value 3.9e-30 272560001185 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 272560001186 6 probable transmembrane helices predicted for BPSL0288 by TMHMM2.0 at aa 12-34, 60-82, 89-111, 116-138, 173-195 and 199-216 272560001187 Similar to Pseudomonas putida glyoxalase SWALL:Q88H56 (EMBL:AE016787) (125 aa) fasta scores: E(): 5.4e-11, 41.52% id in 118 aa, and to Pseudomonas syringae pv. tomato str. DC3000 hypothetical protein SWALL:Q887D4 (EMBL:AE016860) (131 aa) fasta scores: E(): 1.5e-11, 42.99% id in 107 aa. CDS contains a nonsense mutation (amber) after codon 26, and frameshifts after codons 18, 67 and 91;conserved hypothetical protein (pseudogene) 272560001188 Signal peptide predicted for BPSL0289 by SignalP 2.0 HMM (Signal peptide probabilty 0.924) with cleavage site probability 0.919 between residues 39 and 40; signal peptide 272560001189 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560001190 trimer interface [polypeptide binding]; other site 272560001191 eyelet of channel; other site 272560001192 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -62.9, E-value 0.00089 272560001193 Signal peptide predicted for BPSL0290 by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.644 between residues 20 and 21; signal peptide 272560001194 PS00120 Lipases, serine active site. 272560001195 1 probable transmembrane helix predicted for BPSL0291 by TMHMM2.0 at aa 7-26 272560001196 putative membrane protein; Region: HpnL; TIGR03476 272560001197 4 probable transmembrane helices predicted for BPSL0292 by TMHMM2.0 at aa 35-52, 59-81, 150-172 and 179-201 272560001198 Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520 272560001199 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560001200 ligand binding site; other site 272560001201 4 probable transmembrane helices predicted for BPSL0293 by TMHMM2.0 at aa 10-32, 39-61, 331-353 and 374-393 272560001202 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 17.0, E-value 0.00071 272560001203 Signal peptide predicted for BPSL0294 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.912 between residues 38 and 39; signal peptide 272560001204 Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966 272560001205 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 272560001206 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 272560001207 13 probable transmembrane helices predicted for BPSL0295 by TMHMM2.0 at aa 79-98, 113-132, 159-181, 186-208, 221-243, 263-282, 304-326, 357-379, 400-417, 427-449, 462-484, 494-516 and 562-584 272560001208 Pfam match to entry PF01566 Nramp, Natural resistance-associated macrophage protein , score -163.5, E-value 5.4e-08 272560001209 glutathione reductase; Validated; Region: PRK06116 272560001210 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560001211 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560001212 Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852 272560001213 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 302.4, E-value 3.6e-88 272560001214 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272560001215 PS00216 Sugar transport proteins signature 1. 272560001216 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain , score 184.2, E-value 1.3e-52 272560001217 argininosuccinate synthase; Validated; Region: PRK05370 272560001218 Pfam match to entry PF00764 Arginosuc_synth, Arginosuccinate synthase , score 627.3, E-value 5.7e-186 272560001219 PS00564 Argininosuccinate synthase signature 1. 272560001220 PS00565 Argininosuccinate synthase signature 2. 272560001221 4 probable transmembrane helices predicted for BPSL0299 by TMHMM2.0 at aa 70-87, 102-124, 145-167 and 177-196 272560001222 Signal peptide predicted for BPSL0300 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.978 between residues 24 and 25; signal peptide 272560001223 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 272560001224 metal-binding site [ion binding] 272560001225 Pfam match to entry PF00403 HMA, Heavy-metal-associated domain , score 37.2, E-value 2.4e-08 272560001226 PS01047 Heavy-metal-associated domain. 272560001227 YHS domain; Region: YHS; pfam04945 272560001228 copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511 272560001229 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560001230 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 272560001231 8 probable transmembrane helices predicted for BPSL0302 by TMHMM2.0 at aa 141-163, 183-205, 217-239, 254-276, 409-431, 441-463, 753-775 and 780-802 272560001232 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 117.7, E-value 1.4e-32 272560001233 PS00154 E1-E2 ATPases phosphorylation site. 272560001234 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 298.8, E-value 4.5e-87 272560001235 Signal peptide predicted for BPSL0303 by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.434 between residues 36 and 37; signal peptide 272560001236 LemA family; Region: LemA; pfam04011 272560001237 Pfam match to entry PF04011 LemA, LemA family , score 365.1, E-value 4.8e-107 272560001238 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001239 Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512 272560001240 Signal peptide predicted for BPSL0304 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.677 between residues 24 and 25; signal peptide 272560001241 2 probable transmembrane helices predicted for BPSL0304 by TMHMM2.0 at aa 178-200 and 215-237 272560001242 TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase; Region: TPM; pfam04536 272560001243 1 probable transmembrane helix predicted for BPSL0306 by TMHMM2.0 at aa 36-58 272560001244 Signal peptide predicted for BPSL0307 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.921 between residues 34 and 35; signal peptide 272560001245 Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169 272560001246 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 272560001247 Outer membrane efflux protein; Region: OEP; pfam02321 272560001248 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 10.8, E-value 0.0003 272560001249 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 15.4, E-value 0.00015 272560001250 Signal peptide predicted for BPSL0308 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.395 between residues 42 and 43; signal peptide 272560001251 copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783 272560001252 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560001253 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 272560001254 Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696 272560001255 Signal peptide predicted for BPSL0309 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.376 between residues 32 and 33; signal peptide 272560001256 MMPL family; Region: MMPL; cl14618 272560001257 MMPL family; Region: MMPL; cl14618 272560001258 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1224.9, E-value 0 272560001259 10 probable transmembrane helices predicted for BPSL0309 by TMHMM2.0 at aa 13-30, 357-379, 386-408, 483-505, 533-555, 869-891, 898-920, 924-946, 985-1004 and 1014-1036 272560001260 Signal peptide predicted for BPSL0310 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.949 between residues 20 and 21; signal peptide 272560001261 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 272560001262 Avidin family; Region: Avidin; pfam01382 272560001263 Pfam match to entry PF01382 Avidin, Avidin family , score 41.3, E-value 1.4e-09 272560001264 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 272560001265 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 272560001266 glutaminase active site [active] 272560001267 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 272560001268 dimer interface [polypeptide binding]; other site 272560001269 active site 272560001270 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 272560001271 dimer interface [polypeptide binding]; other site 272560001272 active site 272560001273 Pfam match to entry PF01380 SIS, SIS domain , score 120.6, E-value 1.9e-33 272560001274 Pfam match to entry PF01380 SIS, SIS domain , score 127.5, E-value 1.5e-35 272560001275 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 231.7, E-value 7.1e-67 272560001276 PS00443 Glutamine amidotransferases class-II active site. 272560001277 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207 272560001278 N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540 272560001279 Substrate binding site; other site 272560001280 Mg++ binding site; other site 272560001281 N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353 272560001282 active site 272560001283 substrate binding site [chemical binding]; other site 272560001284 CoA binding site [chemical binding]; other site 272560001285 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 9.6, E-value 2.8 272560001286 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 2.2, E-value 25 272560001287 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 8.8, E-value 3.6 272560001288 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.9, E-value 0.13 272560001289 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 18.7, E-value 0.0088 272560001290 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 1.3, E-value 32 272560001291 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score -1.4, E-value 2.9e-08 272560001292 tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696 272560001293 This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This subfamily; Region: Alpha_ANH_like_II; cd01993 272560001294 Ligand Binding Site [chemical binding]; other site 272560001295 Pfam match to entry PF01171 UPF0021, Uncharacterized protein family UPF0021 , score -36.5, E-value 1.1e-06 272560001296 Dihydroneopterin aldolase; Region: FolB; pfam02152 272560001297 active site 272560001298 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560001299 NAD(P) binding site [chemical binding]; other site 272560001300 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 272560001301 active site 272560001302 PS00216 Sugar transport proteins signature 1. 272560001303 Uncharacterized conserved protein [Function unknown]; Region: COG1565 272560001304 Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636 272560001305 Pfam match to entry PF02636 DUF185, Uncharacterized ACR, COG1565 , score 144.1, E-value 1.7e-40 272560001306 Protein of unknown function (DUF2905); Region: DUF2905; pfam11146 272560001307 2 probable transmembrane helices predicted for BPSL0318 by TMHMM2.0 at aa 2-21 and 41-63 272560001308 bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed; Region: PRK06975 272560001309 Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167 272560001310 putative substrate binding site [chemical binding]; other site 272560001311 putative ATP binding site [chemical binding]; other site 272560001312 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 178.4, E-value 7.4e-51 272560001313 PS00584 pfkB family of carbohydrate kinases signature 2. 272560001314 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 174-195, sequence ARMAELADLIKVSDEDLRHLFA 272560001315 PS00583 pfkB family of carbohydrate kinases signature 1. 272560001316 AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249 272560001317 dimerization interface [polypeptide binding]; other site 272560001318 putative active cleft [active] 272560001319 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001320 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560001321 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560001322 DNA binding site [nucleotide binding] 272560001323 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 272560001324 ligand binding site [chemical binding]; other site 272560001325 dimerization interface [polypeptide binding]; other site 272560001326 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 39.0, E-value 6.9e-09 272560001327 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family , score 36.2, E-value 4.9e-08 272560001328 Predicted helix-turn-helix motif with score 2170.000, SD 6.58 at aa 3-24, sequence TTIRDVAQAANVSIGTVSRALK 272560001329 PS00356 Bacterial regulatory proteins, lacI family signature. 272560001330 Signal peptide predicted for BPSL0323 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.627 between residues 32 and 33; signal peptide 272560001331 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560001332 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050 272560001333 dimer interface [polypeptide binding]; other site 272560001334 putative CheW interface [polypeptide binding]; other site 272560001335 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 269.8, E-value 2.3e-78 272560001336 2 probable transmembrane helices predicted for BPSL0323 by TMHMM2.0 at aa 13-35 and 188-210 272560001337 SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593 272560001338 9 probable transmembrane helices predicted for BPSL0324 by TMHMM2.0 at aa 7-25, 35-52, 65-87, 97-119, 131-153, 163-185, 198-220, 233-255 and 276-298 272560001339 Pfam match to entry PF01758 SBF, Sodium Bile acid symporter family , score -7.0, E-value 0.00021 272560001340 Signal peptide predicted for BPSL0325 by SignalP 2.0 HMM (Signal peptide probabilty 0.718) with cleavage site probability 0.430 between residues 17 and 18; signal peptide 272560001341 Signal peptide predicted for BPSL0326 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.678 between residues 30 and 31; signal peptide 272560001342 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560001343 trimer interface [polypeptide binding]; other site 272560001344 eyelet of channel; other site 272560001345 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -98.8, E-value 0.024 272560001346 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560001347 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560001348 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560001349 putative effector binding pocket; other site 272560001350 dimerization interface [polypeptide binding]; other site 272560001351 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 61.0, E-value 1.7e-15 272560001352 PS00044 Bacterial regulatory proteins, lysR family signature. 272560001353 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 175.7, E-value 5e-50 272560001354 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 272560001355 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 272560001356 FMN binding site [chemical binding]; other site 272560001357 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase , score 50.3, E-value 2.7e-12 272560001358 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560001359 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560001360 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 50.1, E-value 3.2e-12 272560001361 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560001362 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560001363 dimerization interface [polypeptide binding]; other site 272560001364 putative DNA binding site [nucleotide binding]; other site 272560001365 putative Zn2+ binding site [ion binding]; other site 272560001366 AsnC family; Region: AsnC_trans_reg; pfam01037 272560001367 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 66.7, E-value 3.3e-17 272560001368 PS00519 Bacterial regulatory proteins, asnC family signature. 272560001369 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560001370 EamA-like transporter family; Region: EamA; pfam00892 272560001371 EamA-like transporter family; Region: EamA; pfam00892 272560001372 10 probable transmembrane helices predicted for BPSL0331 by TMHMM2.0 at aa 13-31, 41-63, 72-94, 99-121, 128-146, 161-178, 185-207, 217-239, 244-266 and 270-292 272560001373 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 40.1, E-value 3.2e-09 272560001374 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 69.3, E-value 5.4e-18 272560001375 This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333 272560001376 putative deacylase active site [active] 272560001377 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560001378 Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119 272560001379 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938 272560001380 active site 272560001381 catalytic residues [active] 272560001382 metal binding site [ion binding]; metal-binding site 272560001383 Pfam match to entry PF00682 HMGL-like, HMGL-like , score 262.5, E-value 3.6e-76 272560001384 PS01062 Hydroxymethylglutaryl-coenzyme A lyase active site. 272560001385 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111 272560001386 Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164 272560001387 putative ligand binding site [chemical binding]; other site 272560001388 NAD binding site [chemical binding]; other site 272560001389 dimerization interface [polypeptide binding]; other site 272560001390 catalytic site [active] 272560001391 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 68.2, E-value 1.1e-17 272560001392 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560001393 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_18; cd08357 272560001394 putative metal binding site [ion binding]; other site 272560001395 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 26.6, E-value 3.8e-05 272560001396 Serine hydrolase; Region: Ser_hydrolase; cl17834 272560001397 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_20; cd04679 272560001398 nudix motif; other site 272560001399 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 88.8, E-value 6.9e-24 272560001400 PS00893 mutT domain signature. 272560001401 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 272560001402 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560001403 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560001404 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560001405 PS00389 ATP synthase delta (OSCP) subunit signature. 272560001406 Signal peptide predicted for BPSL0339 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.561 between residues 24 and 25; signal peptide 272560001407 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001408 1 probable transmembrane helix predicted for BPSL0339 by TMHMM2.0 at aa 7-24 272560001409 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560001410 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560001411 putative DNA binding site [nucleotide binding]; other site 272560001412 putative Zn2+ binding site [ion binding]; other site 272560001413 AsnC family; Region: AsnC_trans_reg; pfam01037 272560001414 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 151.6, E-value 8.9e-43 272560001415 Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296 272560001416 5 probable transmembrane helices predicted for BPSL0341 by TMHMM2.0 at aa 21-43, 81-103, 145-167, 177-191 and 204-226 272560001417 Pfam match to entry PF03591 AzlC, AzlC protein , score 199.2, E-value 4.2e-57 272560001418 Predicted membrane protein [Function unknown]; Region: COG4541 272560001419 3 probable transmembrane helices predicted for BPSL0342 by TMHMM2.0 at aa 4-26, 39-58 and 73-95 272560001420 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560001421 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 68.8, E-value 7.3e-18 272560001422 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560001423 Signal peptide predicted for BPSL0344 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.876 between residues 24 and 25; signal peptide 272560001424 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560001425 Cu(I) binding site [ion binding]; other site 272560001426 Pfam match to entry PF02630 SCO1-SenC, SCO1/SenC , score 37.7, E-value 6.8e-10 272560001427 Glyoxal oxidase N-terminus; Region: Glyoxal_oxid_N; pfam07250 272560001428 Kelch motif; Region: Kelch_6; pfam13964 272560001429 C-terminal Early set domain associated with the catalytic domain of galactose oxidase; Region: E_set_GO_C; cd02851 272560001430 Pfam match to entry PF01344 Kelch, Kelch motif , score 27.7, E-value 1.8e-05 272560001431 Pfam match to entry PF01344 Kelch, Kelch motif , score 23.7, E-value 0.00028 272560001432 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 272560001433 dimer interface [polypeptide binding]; other site 272560001434 active site 272560001435 catalytic residue [active] 272560001436 Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase , score 198.6, E-value 6.5e-57 272560001437 PS00666 Dihydrodipicolinate synthetase signature 2. 272560001438 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560001439 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560001440 Inclusion body protein; Region: PixA; pfam12306 272560001441 Inclusion body protein; Region: PixA; pfam12306 272560001442 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944 272560001443 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score -38.8, E-value 6e-12 272560001444 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 51.4, E-value 1.3e-12 272560001445 Predicted helix-turn-helix motif with score 1299.000, SD 3.61 at aa 38-59, sequence GNLTAAANQLGIAKNTLYERVR 272560001446 Signal peptide predicted for BPSL0352 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 26 and 27; signal peptide 272560001447 ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613 272560001448 Pfam match to entry PF01100 Sulphate_bind, Prokaryotic sulphate- and thiosulphate-binding protein , score 539.7, E-value 1.3e-159 272560001449 Signal peptide predicted for BPSL0353 by SignalP 2.0 HMM (Signal peptide probabilty 0.721) with cleavage site probability 0.415 between residues 26 and 27; signal peptide 272560001450 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 272560001451 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 272560001452 Signal peptide predicted for BPSL0354 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.639 between residues 28 and 29; signal peptide 272560001453 Inward rectifier potassium channel; Region: IRK; pfam01007 272560001454 Pfam match to entry PF01007 IRK, Inward rectifier potassium channel , score -27.4, E-value 4.1e-15 272560001455 3 probable transmembrane helices predicted for BPSL0355 by TMHMM2.0 at aa 60-82, 95-114 and 124-146 272560001456 2-oxoacid ferredoxin oxidoreductase; Provisional; Region: PRK13030 272560001457 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 272560001458 dimer interface [polypeptide binding]; other site 272560001459 PYR/PP interface [polypeptide binding]; other site 272560001460 TPP binding site [chemical binding]; other site 272560001461 substrate binding site [chemical binding]; other site 272560001462 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 272560001463 TPP-binding site [chemical binding]; other site 272560001464 Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558 272560001465 Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546 272560001466 Pfam match to entry PF01558 POR, Pyruvate ferredoxin/flavodoxin oxidoreductase , score 3.8, E-value 1.3e-06 272560001467 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001468 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 272560001469 Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831 272560001470 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 295.4, E-value 4.7e-86 272560001471 11 probable transmembrane helices predicted for BPSL0357 by TMHMM2.0 at aa 87-109, 114-136, 146-163, 176-198, 203-225, 270-292, 312-334, 366-388, 403-425, 446-468 and 488-510 272560001472 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560001473 Pfam match to entry PF00563 EAL, EAL domain , score 101.4, E-value 1.2e-27 272560001474 Signal peptide predicted for BPSL0359 by SignalP 2.0 HMM (Signal peptide probabilty 0.735) with cleavage site probability 0.375 between residues 30 and 31; signal peptide 272560001475 4 probable transmembrane helices predicted for BPSL0359 by TMHMM2.0 at aa 7-29, 44-66, 73-92 and 96-113 272560001476 Signal peptide predicted for BPSL0360 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.350 between residues 33 and 34; signal peptide 272560001477 Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785 272560001478 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 272560001479 dimer interface [polypeptide binding]; other site 272560001480 active site 272560001481 Pfam match to entry PF00245 alk_phosphatase, Alkaline phosphatase , score 340.0, E-value 1.7e-99 272560001482 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001483 Signal peptide predicted for BPSL0361 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 27 and 28; signal peptide 272560001484 Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016 272560001485 active site 272560001486 dimer interface [polypeptide binding]; other site 272560001487 Pfam match to entry PF00245 alk_phosphatase, Alkaline phosphatase , score 283.6, E-value 1.6e-82 272560001488 Signal peptide predicted for BPSL0362 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 34 and 35; signal peptide 272560001489 CutC family; Region: CutC; cl01218 272560001490 Pfam match to entry PF03932 CutC, CutC family , score 157.8, E-value 1.2e-44 272560001491 biotin synthase; Region: bioB; TIGR00433 272560001492 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560001493 FeS/SAM binding site; other site 272560001494 Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876 272560001495 Pfam match to entry PF01792 Biotin_synth, Biotin synthase , score 639.9, E-value 8.9e-190 272560001496 dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090 272560001497 AAA domain; Region: AAA_26; pfam13500 272560001498 Pfam match to entry PF01656 CbiA, Cobyrinic acid a,c-diamide synthase , score 35.5, E-value 8.2e-08 272560001499 8-amino-7-oxononanoate synthase; Reviewed; Region: PRK05958 272560001500 8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858 272560001501 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560001502 catalytic residue [active] 272560001503 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 103.5, E-value 2.7e-28 272560001504 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560001505 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560001506 inhibitor-cofactor binding pocket; inhibition site 272560001507 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560001508 catalytic residue [active] 272560001509 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 401.6, E-value 4.8e-118 272560001510 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560001511 PS00436 Peroxidases active site signature. 272560001512 Signal peptide predicted for BPSL0368 by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.952 between residues 16 and 17; signal peptide 272560001513 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 272560001514 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560001515 hypothetical protein; Provisional; Region: PRK01842 272560001516 short chain dehydrogenase; Provisional; Region: PRK06953 272560001517 short chain dehydrogenase; Region: adh_short; pfam00106 272560001518 NAD(P) binding site [chemical binding]; other site 272560001519 active site 272560001520 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 41.8, E-value 5.2e-10 272560001521 acetyl-CoA acetyltransferase; Provisional; Region: PRK06954 272560001522 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560001523 dimer interface [polypeptide binding]; other site 272560001524 active site 272560001525 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 188.4, E-value 7.4e-54 272560001526 PS00099 Thiolases active site. 272560001527 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 388.0, E-value 6.1e-114 272560001528 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883 272560001529 active site clefts [active] 272560001530 zinc binding site [ion binding]; other site 272560001531 dimer interface [polypeptide binding]; other site 272560001532 Pfam match to entry PF00484 Pro_CA, Carbonic anhydrase , score 179.9, E-value 2.7e-51 272560001533 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 272560001534 bifunctional isocitrate dehydrogenase kinase/phosphatase protein; Validated; Region: aceK; PRK02946 272560001535 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 272560001536 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 34.5, E-value 1.6e-07 272560001537 ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488 272560001538 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560001539 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560001540 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560001541 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 113.0, E-value 3.6e-31 272560001542 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001543 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 104.7, E-value 1.1e-28 272560001544 PS00211 ABC transporters family signature. 272560001545 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001546 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 272560001547 The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493 272560001548 peptide binding site [polypeptide binding]; other site 272560001549 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 561.7, E-value 3.1e-166 272560001550 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 272560001551 active site 272560001552 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score -107.9, E-value 6.6e-05 272560001553 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560001554 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560001555 putative Zn2+ binding site [ion binding]; other site 272560001556 putative DNA binding site [nucleotide binding]; other site 272560001557 Pfam match to entry PF01047 MarR, MarR family , score 25.9, E-value 5.6e-06 272560001558 Predicted helix-turn-helix motif with score 1001.000, SD 2.60 at aa 71-92, sequence LPTGELATRLLLDQTTLSRTLA 272560001559 short chain dehydrogenase; Validated; Region: PRK08264 272560001560 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560001561 NAD(P) binding site [chemical binding]; other site 272560001562 active site 272560001563 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 76.3, E-value 4.1e-20 272560001564 PS00079 Multicopper oxidases signature 1. 272560001565 Signal peptide predicted for BPSL0380 by SignalP 2.0 HMM (Signal peptide probabilty 0.973) with cleavage site probability 0.969 between residues 23 and 24; signal peptide 272560001566 short chain dehydrogenase; Provisional; Region: PRK07024 272560001567 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560001568 NAD(P) binding site [chemical binding]; other site 272560001569 active site 272560001570 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 124.4, E-value 1.4e-34 272560001571 PS00061 Short-chain dehydrogenases/reductases family signature. 272560001572 Signal peptide predicted for BPSL0381 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.986 between residues 21 and 22; signal peptide 272560001573 DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019 272560001574 catalytic residues [active] 272560001575 hinge region; other site 272560001576 alpha helical domain; other site 272560001577 Pfam match to entry PF01323 DSBA, DSBA oxidoreductase , score 59.9, E-value 3.7e-15 272560001578 PS00194 Thioredoxin family active site. 272560001579 Cell division protein [Cell division and chromosome partitioning]; Region: FtsN; COG3087 272560001580 Sporulation related domain; Region: SPOR; pfam05036 272560001581 1 probable transmembrane helix predicted for BPSL0382 by TMHMM2.0 at aa 21-43 272560001582 arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611 272560001583 Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016 272560001584 catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671 272560001585 active site 272560001586 HIGH motif; other site 272560001587 KMSK motif region; other site 272560001588 Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956 272560001589 tRNA binding surface [nucleotide binding]; other site 272560001590 anticodon binding site; other site 272560001591 Pfam match to entry PF00750 tRNA-synt_1d, tRNA synthetases class I (R) , score 232.4, E-value 4.2e-67 272560001592 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560001593 Pfam match to entry PF03485 N-Arg, Arginyl tRNA synthetase N terminal domain , score 82.8, E-value 4.6e-22 272560001594 Domain of unknown function (DUF1840); Region: DUF1840; pfam08895 272560001595 Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410 272560001596 MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). Cobalamin-dependent...; Region: MeTr; cd00740 272560001597 substrate binding pocket [chemical binding]; other site 272560001598 B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069 272560001599 B12 binding site [chemical binding]; other site 272560001600 cobalt ligand [ion binding]; other site 272560001601 Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965 272560001602 Pfam match to entry PF02965 Met_synt_B12, Vitamin B12 dependent methionine synthase, activation domain , score 456.1, E-value 2e-134 272560001603 Pfam match to entry PF02310 B12-binding, B12 binding domain , score 162.4, E-value 5e-46 272560001604 Pfam match to entry PF02607 B12-binding_2, B12 binding domain , score 159.4, E-value 4.1e-45 272560001605 Pfam match to entry PF00809 Pterin_bind, Pterin binding enzyme , score 297.9, E-value 8e-87 272560001606 Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646 272560001607 Pfam match to entry PF02574 S-methyl_trans, Homocysteine S-methyltransferase , score 482.8, E-value 1.8e-142 272560001608 Protein of unknown function (DUF3567); Region: DUF3567; pfam12091 272560001609 Signal peptide predicted for BPSL0400 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.301 between residues 18 and 19; signal peptide 272560001610 Protein of unknown function (DUF3108); Region: DUF3108; pfam11306 272560001611 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560001612 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560001613 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score -5.7, E-value 7.3e-08 272560001614 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001615 PS00043 Bacterial regulatory proteins, gntR family signature. 272560001616 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 272560001617 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560001618 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score -31.2, E-value 2.4e-06 272560001619 enoyl-CoA hydratase; Provisional; Region: PRK07658 272560001620 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560001621 substrate binding site [chemical binding]; other site 272560001622 oxyanion hole (OAH) forming residues; other site 272560001623 trimer interface [polypeptide binding]; other site 272560001624 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 68.3, E-value 1e-17 272560001625 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560001626 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 272560001627 Signal peptide predicted for BPSL0393 by SignalP 2.0 HMM (Signal peptide probabilty 0.830) with cleavage site probability 0.510 between residues 17 and 18; signal peptide 272560001628 Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396 272560001629 active site 272560001630 nucleophile elbow; other site 272560001631 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 63.1, E-value 4e-16 272560001632 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264 272560001633 dinuclear metal binding motif [ion binding]; other site 272560001634 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870 272560001635 rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199 272560001636 active site 272560001637 nucleotide binding site [chemical binding]; other site 272560001638 HIGH motif; other site 272560001639 KMSKS motif; other site 272560001640 Pfam match to entry PF01467 CTP_transf_2, Cytidylyltransferase , score 122.3, E-value 6e-34 272560001641 Signal peptide predicted for BPSL0396 by SignalP 2.0 HMM (Signal peptide probabilty 0.882) with cleavage site probability 0.247 between residues 29 and 30; signal peptide 272560001642 pantothenate kinase; Reviewed; Region: PRK13328 272560001643 Pfam match to entry PF03309 Bvg_acc_factor, Bordetella pertussis Bvg accessory factor family , score 59.1, E-value 6.3e-15 272560001644 biotin--protein ligase; Provisional; Region: PRK06955 272560001645 Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057 272560001646 Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237 272560001647 Pfam match to entry PF02237 BPL_C, Biotin protein ligase C terminal domain , score 41.8, E-value 1e-09 272560001648 Pfam match to entry PF03099 BPL_LipA_LipB, Biotin/lipoate A/B protein ligase , score 39.2, E-value 6.3e-09 272560001649 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 272560001650 Sel1-like repeats; Region: SEL1; smart00671 272560001651 Sel1-like repeats; Region: SEL1; smart00671 272560001652 1 probable transmembrane helix predicted for BPSL0399 by TMHMM2.0 at aa 30-52 272560001653 Signal peptide predicted for BPSL0400 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.301 between residues 49 and 50; signal peptide 272560001654 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420 272560001655 Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410 272560001656 active site 272560001657 metal binding site [ion binding]; metal-binding site 272560001658 5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872 272560001659 Pfam match to entry PF02872 5_nucleotidaseC, 5'-nucleotidase, C-terminal domain , score 152.1, E-value 6.3e-43 272560001660 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001661 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 45.6, E-value 7e-11 272560001662 PS00786 5'-nucleotidase signature 2. 272560001663 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560001664 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001665 Permease; Region: Permease; pfam02405 272560001666 Pfam match to entry PF02405 DUF140, Domain of unknown function DUF140 , score 183.6, E-value 2.1e-52 272560001667 6 probable transmembrane helices predicted for BPSL0401 by TMHMM2.0 at aa 126-145, 166-188, 198-220, 269-291, 311-333 and 346-368 272560001668 ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127 272560001669 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560001670 Walker A/P-loop; other site 272560001671 ATP binding site [chemical binding]; other site 272560001672 Q-loop/lid; other site 272560001673 ABC transporter signature motif; other site 272560001674 Walker B; other site 272560001675 D-loop; other site 272560001676 H-loop/switch region; other site 272560001677 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 188.3, E-value 7.8e-54 272560001678 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001679 ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463 272560001680 mce related protein; Region: MCE; pfam02470 272560001681 1 probable transmembrane helix predicted for BPSL0403 by TMHMM2.0 at aa 7-29 272560001682 Pfam match to entry PF02470 mce, mce related protein , score 5.5, E-value 0.00015 272560001683 Signal peptide predicted for BPSL0404 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.602 between residues 35 and 36; signal peptide 272560001684 Protein of unknown function (DUF330); Region: DUF330; cl01135 272560001685 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001686 Predicted integral membrane protein [Function unknown]; Region: COG5652 272560001687 10 probable transmembrane helices predicted for BPSL0405 by TMHMM2.0 at aa 20-42, 62-84, 91-110, 125-147, 167-189, 231-253, 260-280, 290-312, 319-338 and 358-377 272560001688 Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980 272560001689 dimer interface [polypeptide binding]; other site 272560001690 [2Fe-2S] cluster binding site [ion binding]; other site 272560001691 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2945 272560001692 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560001693 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 272560001694 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768 272560001695 Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936 272560001696 Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase , score 357.4, E-value 1e-104 272560001697 D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558 272560001698 homodimer interface [polypeptide binding]; other site 272560001699 substrate-cofactor binding pocket; other site 272560001700 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560001701 catalytic residue [active] 272560001702 Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV , score 199.2, E-value 4.3e-57 272560001703 hypothetical protein; Provisional; Region: PRK02047 272560001704 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560001705 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560001706 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560001707 dimerization interface [polypeptide binding]; other site 272560001708 substrate binding pocket [chemical binding]; other site 272560001709 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 151.1, E-value 1.2e-42 272560001710 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 103.8, E-value 2.3e-28 272560001711 PS00044 Bacterial regulatory proteins, lysR family signature. 272560001712 Predicted helix-turn-helix motif with score 1407.000, SD 3.98 at aa 22-43, sequence ESFSRAADELSVTHGAVSHQMR 272560001713 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 272560001714 lipoate-protein ligase B; Provisional; Region: PRK14343 272560001715 Pfam match to entry PF03099 BPL_LipA_LipB, Biotin/lipoate A/B protein ligase , score 111.2, E-value 1.3e-30 272560001716 PS01313 Lipoate-protein ligase B signature. 272560001717 lipoyl synthase; Provisional; Region: PRK05481 272560001718 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560001719 FeS/SAM binding site; other site 272560001720 Pfam match to entry PF02546 Lipoate_synth, Lipoate synthase , score 612.8, E-value 1.3e-181 272560001721 Probable gene remnant. Similar to the C-terminal regions of Rhizobium meliloti probable quinone oxidoreductase ra0019 or sma0041 SWALL:Q931C5 (EMBL:AE007197) (307 aa) fasta scores: E(): 4.4e-23, 53.22% id in 124 aa, and Pasteurella multocida hypothetical protein PM1940 SWALL:Q9CJQ4 (EMBL:AE006230) (236 aa) fasta scores: E(): 3.3e-17, 47.54% id in 122 aa;zinc-binding dehydrogenase (fragment) 272560001722 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 53.8, E-value 2.1e-15 272560001723 PS00228 Tubulin-beta mRNA autoregulation signal. 272560001724 Signal peptide predicted for BPSL0416 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.592 between residues 46 and 47; signal peptide 272560001725 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 272560001726 Pfam match to entry PF01019 G_glu_transpept, Gamma-glutamyltranspeptidase , score 517.1, E-value 8.4e-153 272560001727 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001728 Signal peptide predicted for BPSL0417 by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.648 between residues 36 and 37; signal peptide 272560001729 2 probable transmembrane helices predicted for BPSL0417 by TMHMM2.0 at aa 13-35 and 76-98 272560001730 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560001731 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560001732 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560001733 putative effector binding pocket; other site 272560001734 dimerization interface [polypeptide binding]; other site 272560001735 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 143.5, E-value 2.4e-40 272560001736 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 67.8, E-value 1.5e-17 272560001737 PS00044 Bacterial regulatory proteins, lysR family signature. 272560001738 Predicted helix-turn-helix motif with score 1750.000, SD 5.15 at aa 16-37, sequence GNLSKAAQRLKMSRANVSYRLN 272560001739 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 272560001740 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560001741 substrate binding site [chemical binding]; other site 272560001742 oxyanion hole (OAH) forming residues; other site 272560001743 trimer interface [polypeptide binding]; other site 272560001744 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560001745 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560001746 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560001747 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 192.1, E-value 5.8e-55 272560001748 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 234.6, E-value 9.3e-68 272560001749 PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 272560001750 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 109.2, E-value 5.1e-30 272560001751 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 0.9, E-value 0.0004 272560001752 pimeloyl-CoA dehydrogenase, large subunit; Region: pimC_large; TIGR03204 272560001753 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560001754 active site 272560001755 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 53.7, E-value 2.7e-13 272560001756 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 54.6, E-value 1.4e-13 272560001757 pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203 272560001758 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 272560001759 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 272560001760 active site 272560001761 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 71.1, E-value 1.5e-18 272560001762 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560001763 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 242.2, E-value 4.8e-70 272560001764 PS00213 Lipocalin signature. 272560001765 Protein of unknown function, DUF485; Region: DUF485; pfam04341 272560001766 2 probable transmembrane helices predicted for BPSL0423 by TMHMM2.0 at aa 25-47 and 62-84 272560001767 Signal peptide predicted for BPSL0424 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.563 between residues 40 and 41; signal peptide 272560001768 Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480 272560001769 Na binding site [ion binding]; other site 272560001770 14 probable transmembrane helices predicted for BPSL0424 by TMHMM2.0 at aa 20-42, 52-71, 84-106, 121-143, 163-185, 195-217, 230-252, 282-304, 316-338, 388-410, 431-453, 458-480, 487-506 and 521-543 272560001771 Pfam match to entry PF00474 SSF, Sodium:solute symporter family , score 461.2, E-value 5.6e-136 272560001772 C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663 272560001773 8 probable transmembrane helices predicted for BPSL0425 by TMHMM2.0 at aa 21-43, 58-80, 93-115, 160-182, 202-224, 239-261, 330-352 and 367-389 272560001774 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 576.9, E-value 8.4e-171 272560001775 PS00713 Sodium:dicarboxylate symporter family signature 1. 272560001776 PS00714 Sodium:dicarboxylate symporter family signature 2. 272560001777 Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191 272560001778 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560001779 dimer interface [polypeptide binding]; other site 272560001780 phosphorylation site [posttranslational modification] 272560001781 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560001782 ATP binding site [chemical binding]; other site 272560001783 Mg2+ binding site [ion binding]; other site 272560001784 G-X-G motif; other site 272560001785 1 probable transmembrane helix predicted for BPSL0426 by TMHMM2.0 at aa 55-77 272560001786 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 34.5, E-value 1.6e-07 272560001787 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 125.7, E-value 5.7e-35 272560001788 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560001789 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560001790 active site 272560001791 phosphorylation site [posttranslational modification] 272560001792 intermolecular recognition site; other site 272560001793 dimerization interface [polypeptide binding]; other site 272560001794 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560001795 Walker A motif; other site 272560001796 ATP binding site [chemical binding]; other site 272560001797 Walker B motif; other site 272560001798 arginine finger; other site 272560001799 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560001800 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 126.5, E-value 3.1e-35 272560001801 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 437.8, E-value 6.1e-129 272560001802 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560001803 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560001804 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560001805 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 41.8, E-value 1e-09 272560001806 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 272560001807 catalytic residues [active] 272560001808 1 probable transmembrane helix predicted for BPSL0428 by TMHMM2.0 at aa 13-35 272560001809 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560001810 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560001811 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 109.1, E-value 5.7e-30 272560001812 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560001813 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 35.3, E-value 9.2e-08 272560001814 Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606 272560001815 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 272560001816 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560001817 Walker A motif; other site 272560001818 ATP binding site [chemical binding]; other site 272560001819 Walker B motif; other site 272560001820 arginine finger; other site 272560001821 Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335 272560001822 Pfam match to entry PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI , score 185.1, E-value 7.5e-53 272560001823 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001824 Membrane fusogenic activity; Region: BMFP; pfam04380 272560001825 Nitrogen regulatory protein PII [Amino acid transport and metabolism]; Region: GlnK; COG0347 272560001826 Pfam match to entry PF00543 P-II, Nitrogen regulatory protein P-II , score 224.5, E-value 9.9e-65 272560001827 PS00496 P-II protein urydylation site. 272560001828 PS00638 P-II protein C-terminal region signature. 272560001829 Signal peptide predicted for BPSL0435 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.459 between residues 19 and 20; signal peptide 272560001830 Ammonia permease [Inorganic ion transport and metabolism]; Region: AmtB; COG0004 272560001831 Pfam match to entry PF00909 Ammonium_transp, Ammonium Transporter Family , score 524.5, E-value 4.9e-155 272560001832 11 probable transmembrane helices predicted for BPSL0435 by TMHMM2.0 at aa 99-121, 128-150, 196-218, 223-245, 260-282, 295-314, 329-351, 356-375, 379-401, 414-433 and 443-465 272560001833 PS01219 Ammonium transporters signature. 272560001834 Glutamate-cysteine ligase; Region: GshA; pfam08886 272560001835 glutathione synthetase; Provisional; Region: PRK05246 272560001836 Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951 272560001837 Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955 272560001838 Pfam match to entry PF02951 GSH-S_N, Prokaryotic glutathione synthetase, N-terminal domain , score 100.0, E-value 3e-27 272560001839 Pfam match to entry PF02955 GSH-S_ATP, Prokaryotic glutathione synthetase, ATP-binding domain , score 149.8, E-value 3.1e-42 272560001840 PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006 272560001841 active pocket/dimerization site; other site 272560001842 active site 272560001843 phosphorylation site [posttranslational modification] 272560001844 Pfam match to entry PF03610 EIIA-man, PTS system fructose IIA component , score 60.2, E-value 2.9e-15 272560001845 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 272560001846 dimerization domain swap beta strand [polypeptide binding]; other site 272560001847 regulatory protein interface [polypeptide binding]; other site 272560001848 active site 272560001849 regulatory phosphorylation site [posttranslational modification]; other site 272560001850 Pfam match to entry PF00381 PTS-HPr, PTS HPr component phosphorylation site , score 159.6, E-value 3.4e-45 272560001851 PS00369 PTS HPR component histidine phosphorylation site signature. 272560001852 PS00589 PTS HPR component serine phosphorylation site signature. 272560001853 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 272560001854 PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524 272560001855 PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391 272560001856 PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 272560001857 Pfam match to entry PF00391 PEP-utilizers, PEP-utilizing enzyme, mobile domain , score 103.3, E-value 3e-28 272560001858 PS00370 PEP-utilizing enzymes phosphorylation site signature. 272560001859 Pfam match to entry PF02896 PEP-utilizers_C, PEP-utilizing enzyme, TIM barrel domain , score 494.7, E-value 4.6e-146 272560001860 PS00742 PEP-utilizing enzymes signature 2. 272560001861 molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690 272560001862 ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757 272560001863 ATP binding site [chemical binding]; other site 272560001864 substrate interface [chemical binding]; other site 272560001865 Pfam match to entry PF00899 ThiF, ThiF family , score 192.2, E-value 5.3e-55 272560001866 Signal peptide predicted for BPSL0442 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.563 between residues 31 and 32; signal peptide 272560001867 C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560 272560001868 C-terminal peptidase (prc); Region: prc; TIGR00225 272560001869 PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988 272560001870 protein binding site [polypeptide binding]; other site 272560001871 Catalytic dyad [active] 272560001872 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 66.5, E-value 3.7e-17 272560001873 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 272560001874 catalytic core [active] 272560001875 PS00017 ATP/GTP-binding site motif A (P-loop). 272560001876 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score 448.2, E-value 4.6e-132 272560001877 PS00175 Phosphoglycerate mutase phosphohistidine signature. 272560001878 Signal peptide predicted for BPSL0444 by SignalP 2.0 HMM (Signal peptide probabilty 0.961) with cleavage site probability 0.771 between residues 24 and 25; signal peptide 272560001879 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 272560001880 active site residue [active] 272560001881 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 57.8, E-value 1.5e-14 272560001882 Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418 272560001883 GSH binding site [chemical binding]; other site 272560001884 catalytic residues [active] 272560001885 Pfam match to entry PF00462 glutaredoxin, Glutaredoxin , score 50.1, E-value 3.1e-12 272560001886 preprotein translocase subunit SecB; Validated; Region: PRK05751 272560001887 SecA binding site; other site 272560001888 Preprotein binding site; other site 272560001889 Pfam match to entry PF02556 SecB, Preprotein translocase subunit SecB , score 137.5, E-value 1.6e-38 272560001890 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094 272560001891 Signal peptide predicted for BPSL0447 by SignalP 2.0 HMM (Signal peptide probabilty 0.907) with cleavage site probability 0.509 between residues 22 and 23; signal peptide 272560001892 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210 272560001893 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479 272560001894 Pfam match to entry PF01210 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase , score 378.4, E-value 4.9e-111 272560001895 PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 272560001896 Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908 272560001897 putative ADP-ribose binding site [chemical binding]; other site 272560001898 putative active site [active] 272560001899 Pfam match to entry PF01661 A1pp, Appr-1-p processing enzyme family , score 157.7, E-value 1.3e-44 272560001900 Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219 272560001901 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase , score 139.8, E-value 3.3e-39 272560001902 Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040 272560001903 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560001904 active site 272560001905 biotin biosynthesis protein BioC; Region: BioC; TIGR02072 272560001906 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560001907 S-adenosylmethionine binding site [chemical binding]; other site 272560001908 PS00136 Serine proteases, subtilase, aspartic acid active site. 272560001909 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 272560001910 Integral membrane protein (DUF2244); Region: DUF2244; pfam10003 272560001911 2 probable transmembrane helices predicted for BPSL0452 by TMHMM2.0 at aa 43-62 and 66-88 272560001912 Signal peptide predicted for BPSL0453 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 between residues 33 and 34; signal peptide 272560001913 Cytochrome C oxidase subunit II, transmembrane domain; Region: COX2_TM; pfam02790 272560001914 cytochrome c oxidase subunit II; Provisional; Region: COX2; MTH00140 272560001915 Cupredoxin superfamily; Region: Cupredoxin; cl19115 272560001916 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560001917 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 272560001918 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560001919 ligand binding site [chemical binding]; other site 272560001920 3 probable transmembrane helices predicted for BPSL0453 by TMHMM2.0 at aa 12-34, 64-86 and 107-129 272560001921 Pfam match to entry PF02790 COX2_TM, Cytochrome C oxidase subunit II, transmembrane domain , score 50.9, E-value 1.8e-12 272560001922 Pfam match to entry PF00116 COX2, Cytochrome C oxidase subunit II, periplasmic domain , score 161.8, E-value 7.8e-46 272560001923 PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 272560001924 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 42.2, E-value 7.7e-10 272560001925 PS00190 Cytochrome c family heme-binding site signature. 272560001926 Pfam match to entry PF00691 OmpA, OmpA family , score 55.0, E-value 1.1e-13 272560001927 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 272560001928 Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663 272560001929 Subunit I/III interface [polypeptide binding]; other site 272560001930 D-pathway; other site 272560001931 Subunit I/VIIc interface [polypeptide binding]; other site 272560001932 Subunit I/IV interface [polypeptide binding]; other site 272560001933 Subunit I/II interface [polypeptide binding]; other site 272560001934 Low-spin heme (heme a) binding site [chemical binding]; other site 272560001935 Subunit I/VIIa interface [polypeptide binding]; other site 272560001936 Subunit I/VIa interface [polypeptide binding]; other site 272560001937 Dimer interface; other site 272560001938 Putative water exit pathway; other site 272560001939 Binuclear center (heme a3/CuB) [ion binding]; other site 272560001940 K-pathway; other site 272560001941 Subunit I/Vb interface [polypeptide binding]; other site 272560001942 Putative proton exit pathway; other site 272560001943 Subunit I/VIb interface; other site 272560001944 Subunit I/VIc interface [polypeptide binding]; other site 272560001945 Electron transfer pathway; other site 272560001946 Subunit I/VIIIb interface [polypeptide binding]; other site 272560001947 Subunit I/VIIb interface [polypeptide binding]; other site 272560001948 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score 878.0, E-value 2e-261 272560001949 12 probable transmembrane helices predicted for BPSL0454 by TMHMM2.0 at aa 37-59, 79-101, 121-143, 166-188, 208-230, 255-277, 284-306, 321-343, 356-378, 393-415, 428-450 and 470-492 272560001950 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560001951 1 probable transmembrane helix predicted for BPSL0455 by TMHMM2.0 at aa 36-58 272560001952 cytochrome C oxidase assembly protein; Provisional; Region: PRK05089 272560001953 1 probable transmembrane helix predicted for BPSL0456 by TMHMM2.0 at aa 5-27 272560001954 Protein of unknown function (DUF2970); Region: DUF2970; pfam11174 272560001955 1 probable transmembrane helix predicted for BPSL0457 by TMHMM2.0 at aa 43-65 272560001956 Cytochrome c oxidase subunit III. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_III; cd01665 272560001957 Subunit III/VIIa interface [polypeptide binding]; other site 272560001958 Phospholipid binding site [chemical binding]; other site 272560001959 Subunit I/III interface [polypeptide binding]; other site 272560001960 Subunit III/VIb interface [polypeptide binding]; other site 272560001961 Subunit III/VIa interface; other site 272560001962 Subunit III/Vb interface [polypeptide binding]; other site 272560001963 Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III , score 198.1, E-value 8.9e-57 272560001964 7 probable transmembrane helices predicted for BPSL0458 by TMHMM2.0 at aa 20-37, 41-63, 84-106, 146-168, 181-203, 223-245 and 265-284 272560001965 Protein of unknown function (DUF2909); Region: DUF2909; pfam11137 272560001966 SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662 272560001967 1 probable transmembrane helix predicted for BPSL0459 by TMHMM2.0 at aa 145-164 272560001968 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 272560001969 1 probable transmembrane helix predicted for BPSL0460 by TMHMM2.0 at aa 30-52 272560001970 Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628 272560001971 Pfam match to entry PF02628 COX15-CtaA, Cytochrome oxidase assembly protein , score 55.6, E-value 7.2e-14 272560001972 8 probable transmembrane helices predicted for BPSL0461 by TMHMM2.0 at aa 13-30, 80-102, 115-137, 141-163, 184-206, 249-271, 283-305 and 310-332 272560001973 Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957 272560001974 putative active site [active] 272560001975 Pfam match to entry PF01040 UbiA, UbiA prenyltransferase , score 250.7, E-value 1.3e-72 272560001976 9 probable transmembrane helices predicted for BPSL0462 by TMHMM2.0 at aa 27-44, 48-70, 91-113, 118-138, 145-167, 171-193, 214-236, 240-259 and 272-294 272560001977 PS00943 UbiA prenyltransferase signature. 272560001978 Signal peptide predicted for BPSL0463 by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.429 between residues 32 and 33; signal peptide 272560001979 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560001980 Cu(I) binding site [ion binding]; other site 272560001981 Pfam match to entry PF02630 SCO1-SenC, SCO1/SenC , score 111.9, E-value 8e-31 272560001982 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560001983 YCII-related domain; Region: YCII; cl00999 272560001984 Pfam match to entry PF03795 YCII, YCII-related domain , score 58.3, E-value 1.1e-14 272560001985 Signal peptide predicted for BPSL0465 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.848 between residues 28 and 29; signal peptide 272560001986 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 272560001987 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050 272560001988 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560001989 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560001990 dimer interface [polypeptide binding]; other site 272560001991 putative CheW interface [polypeptide binding]; other site 272560001992 2 probable transmembrane helices predicted for BPSL0465 by TMHMM2.0 at aa 10-30 and 187-209 272560001993 Pfam match to entry PF00672 HAMP, HAMP domain , score 13.4, E-value 0.055 272560001994 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 384.8, E-value 5.7e-113 272560001995 Signal peptide predicted for BPSL0466 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.832 between residues 28 and 29; signal peptide 272560001996 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 272560001997 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein , score 453.2, E-value 1.4e-133 272560001998 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879 272560001999 Signal peptide predicted for BPSL0467 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 29 and 30; signal peptide 272560002000 Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325 272560002001 zinc binding site [ion binding]; other site 272560002002 putative ligand binding site [chemical binding]; other site 272560002003 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574 272560002004 TM-ABC transporter signature motif; other site 272560002005 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -36.7, E-value 5.1e-05 272560002006 8 probable transmembrane helices predicted for BPSL0468 by TMHMM2.0 at aa 7-29, 59-81, 88-107, 131-153, 179-201, 211-230, 235-254 and 269-286 272560002007 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101 272560002008 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560002009 Walker A/P-loop; other site 272560002010 ATP binding site [chemical binding]; other site 272560002011 Q-loop/lid; other site 272560002012 ABC transporter signature motif; other site 272560002013 Walker B; other site 272560002014 D-loop; other site 272560002015 H-loop/switch region; other site 272560002016 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 146.5, E-value 3e-41 272560002017 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002018 PS00211 ABC transporters family signature. 272560002019 Probable gene fusion. N-terminus is weakly similar to the N-terminal region of Proteus vulgaris recombinase A RecA SWALL:RECA_PROVU (SWALL:P26346) (325 aa) fasta scores: E(): 0.33, 25% id in 136 aa. Similar to the N-terminal region of Ralstonia solanacearum hypothetical protein rsp0798 or rs01909 SWALL:Q8XRN3 (EMBL:AL646080) (272 aa) fasta scores: E(): 6.8e-31, 47.98% id in 223 aa;hypothetical protein (pseudogene) 272560002020 DNA Polymerase Y-family; Region: PolY_like; cd03468 272560002021 active site 272560002022 DNA binding site [nucleotide binding] 272560002023 error-prone DNA polymerase; Validated; Region: dnaE2; PRK05672 272560002024 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at DnaE2 gene; Region: PHP_PolIIIA_DnaE2; cd07434 272560002025 putative active site [active] 272560002026 putative PHP Thumb interface [polypeptide binding]; other site 272560002027 Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733 272560002028 Helix-hairpin-helix motif; Region: HHH_6; pfam14579 272560002029 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 272560002030 generic binding surface II; other site 272560002031 generic binding surface I; other site 272560002032 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region , score 49.6, E-value 4.4e-12 272560002033 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560002034 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560002035 putative substrate translocation pore; other site 272560002036 12 probable transmembrane helices predicted for BPSL0474 by TMHMM2.0 at aa 63-82, 97-119, 126-145, 155-174, 187-209, 213-235, 261-283, 293-315, 327-345, 350-372, 384-406 and 411-433 272560002037 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -113.3, E-value 0.00073 272560002038 This CD includes the dihydrorhizobitoxine fatty acid desaturase (RtxC) characterized in Bradyrhizobium japonicum USDA110, and other related proteins. Dihydrorhizobitoxine desaturase is reported to be involved in the final step of rhizobitoxine...; Region: Rhizobitoxine-FADS-like; cd03510 272560002039 putative di-iron ligands [ion binding]; other site 272560002040 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 76.3, E-value 4.3e-20 272560002041 3 probable transmembrane helices predicted for BPSL0475 by TMHMM2.0 at aa 34-56, 71-90 and 216-238 272560002042 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560002043 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560002044 inhibitor-cofactor binding pocket; inhibition site 272560002045 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560002046 catalytic residue [active] 272560002047 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 428.0, E-value 5.4e-126 272560002048 3 probable transmembrane helices predicted for BPSL0477 by TMHMM2.0 at aa 7-29, 60-82 and 89-111 272560002049 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560002050 ABC-2 type transporter; Region: ABC2_membrane; cl17235 272560002051 6 probable transmembrane helices predicted for BPSL0478 by TMHMM2.0 at aa 21-40, 166-188, 209-231, 246-268, 281-303 and 336-358 272560002052 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152 272560002053 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560002054 Walker A/P-loop; other site 272560002055 ATP binding site [chemical binding]; other site 272560002056 Q-loop/lid; other site 272560002057 ABC transporter signature motif; other site 272560002058 Walker B; other site 272560002059 D-loop; other site 272560002060 H-loop/switch region; other site 272560002061 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 86.6, E-value 3.4e-23 272560002062 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain , score 21.0, E-value 3.8e-06 272560002063 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002064 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 272560002065 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560002066 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560002067 S-adenosylmethionine binding site [chemical binding]; other site 272560002068 PS00093 N-4 cytosine-specific DNA methylases signature. 272560002069 Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416 272560002070 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 272560002071 citrylCoA binding site [chemical binding]; other site 272560002072 oxalacetate binding site [chemical binding]; other site 272560002073 coenzyme A binding site [chemical binding]; other site 272560002074 catalytic triad [active] 272560002075 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 272560002076 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 272560002077 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560002078 active site 272560002079 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 272560002080 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 139.7, E-value 3.4e-39 272560002081 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 272560002082 active site 272560002083 PS00211 ABC transporters family signature. 272560002084 acyl-CoA ligase (AMP-forming), exosortase A-associated; Region: ligase_PEP_1; TIGR03098 272560002085 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560002086 acyl-activating enzyme (AAE) consensus motif; other site 272560002087 AMP binding site [chemical binding]; other site 272560002088 active site 272560002089 CoA binding site [chemical binding]; other site 272560002090 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 370.5, E-value 1.1e-108 272560002091 PS00455 AMP-binding domain signature. 272560002092 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Ornithine and Diaminopimelate Decarboxylases, and Related Enzymes; Region: PLPDE_III_ODC_DapDC_like; cd06810 272560002093 Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019 272560002094 dimer interface [polypeptide binding]; other site 272560002095 active site 272560002096 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560002097 catalytic residues [active] 272560002098 substrate binding site [chemical binding]; other site 272560002099 Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain , score 2.3, E-value 2.7e-06 272560002100 Pfam match to entry PF02784 Orn_Arg_deC_N, Pyridoxal-dependent decarboxylase, pyridoxal binding domain , score -22.8, E-value 9.8e-08 272560002101 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 272560002102 active site 272560002103 P-aminobenzoate N-oxygenase AurF; Region: AurF; pfam11583 272560002104 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 272560002105 dinuclear metal binding motif [ion binding]; other site 272560002106 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560002107 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560002108 acyl-CoA synthetase; Validated; Region: PRK09192 272560002109 acyl-activating enzyme (AAE) consensus motif; other site 272560002110 active site 272560002111 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 245.5, E-value 4.9e-71 272560002112 PS00455 AMP-binding domain signature. 272560002113 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560002114 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560002115 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 272560002116 dimerization interface [polypeptide binding]; other site 272560002117 substrate binding pocket [chemical binding]; other site 272560002118 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 107.5, E-value 1.7e-29 272560002119 Predicted helix-turn-helix motif with score 1279.000, SD 3.54 at aa 32-53, sequence LHFGKAAQRLHLAQPPLTRHIS 272560002120 PS00044 Bacterial regulatory proteins, lysR family signature. 272560002121 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 150.3, E-value 2.2e-42 272560002122 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 272560002123 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560002124 DNA-binding site [nucleotide binding]; DNA binding site 272560002125 UTRA domain; Region: UTRA; pfam07702 272560002126 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 60.4, E-value 2.5e-15 272560002127 N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820 272560002128 N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854 272560002129 active site 272560002130 dimer interface [polypeptide binding]; other site 272560002131 Pfam match to entry PF02612 NagA, N-acetylglucosamine-6-phosphate deacetylase , score 204.1, E-value 1.4e-58 272560002132 Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222 272560002133 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 272560002134 dimer interface [polypeptide binding]; other site 272560002135 active site 272560002136 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 272560002137 dimer interface [polypeptide binding]; other site 272560002138 active site 272560002139 Pfam match to entry PF01380 SIS, SIS domain , score 38.1, E-value 1.3e-08 272560002140 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002141 Pfam match to entry PF01380 SIS, SIS domain , score 42.2, E-value 7.6e-10 272560002142 Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190 272560002143 HPr interaction site; other site 272560002144 glycerol kinase (GK) interaction site [polypeptide binding]; other site 272560002145 active site 272560002146 phosphorylation site [posttranslational modification] 272560002147 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 272560002148 dimerization domain swap beta strand [polypeptide binding]; other site 272560002149 regulatory protein interface [polypeptide binding]; other site 272560002150 active site 272560002151 regulatory phosphorylation site [posttranslational modification]; other site 272560002152 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080 272560002153 PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524 272560002154 PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391 272560002155 PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 272560002156 Pfam match to entry PF00358 PTS_EIIA_1, phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 , score 156.1, E-value 3.9e-44 272560002157 PS00371 PTS EIIA domains phosphorylation site signature 1. 272560002158 Pfam match to entry PF00381 PTS-HPr, PTS HPr component phosphorylation site , score 48.7, E-value 8.7e-12 272560002159 PS00369 PTS HPR component histidine phosphorylation site signature. 272560002160 Pfam match to entry PF00391 PEP-utilizers, PEP-utilizing enzyme, mobile domain , score 94.6, E-value 1.3e-25 272560002161 PS00370 PEP-utilizing enzymes phosphorylation site signature. 272560002162 Pfam match to entry PF02896 PEP-utilizers_C, PEP-utilizing enzyme, TIM barrel domain , score 399.6, E-value 1.9e-117 272560002163 PS00742 PEP-utilizing enzymes signature 2. 272560002164 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263 272560002165 PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998 272560002166 PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212 272560002167 active site turn [active] 272560002168 phosphorylation site [posttranslational modification] 272560002169 Phosphotransferase system IIB components [Carbohydrate transport and metabolism]; Region: PtsG; COG1264 272560002170 active site turn [active] 272560002171 phosphorylation site [posttranslational modification] 272560002172 10 probable transmembrane helices predicted for BPSL0499 by TMHMM2.0 at aa 15-37, 50-71, 100-117, 138-160, 170-192, 197-219, 234-256, 263-282, 297-319 and 340-362 272560002173 Pfam match to entry PF02378 PTS_EIIC, Phosphotransferase system, EIIC , score 422.4, E-value 2.7e-124 272560002174 Pfam match to entry PF00367 PTS_EIIB, phosphotransferase system, EIIB , score 49.9, E-value 3.6e-12 272560002175 PS01035 PTS EIIB domains cysteine phosphorylation site signature. 272560002176 Pfam match to entry PF00367 PTS_EIIB, phosphotransferase system, EIIB , score 26.0, E-value 2.6e-05 272560002177 Signal peptide predicted for BPSL0500 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.865 between residues 25 and 26; signal peptide 272560002178 Putative carbohydrate binding domain; Region: CHB_HEX; smart01081 272560002179 N-acetyl-beta-hexosaminidase [Carbohydrate transport and metabolism]; Region: Chb; COG3525 272560002180 Glycosyl hydrolase family 20, domain 2; Region: Glyco_hydro_20b; pfam02838 272560002181 Beta-N-acetylhexosaminidases of glycosyl hydrolase family 20 (GH20) catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides; Region: GH20_hexosaminidase; cl02948 272560002182 active site 272560002183 Pfam match to entry PF00728 Glyco_hydro_20, Glycosyl hydrolase 20, catalytic domain , score 504.9, E-value 3.9e-149 272560002184 PS00018 EF-hand calcium-binding domain. 272560002185 Pfam match to entry PF02838 Glyco_hydro_20b, Glycosyl hydrolase 20, domain 2 , score 0.8, E-value 0.00032 272560002186 Pfam match to entry PF03173 CHB_HEX, carbohydrate binding domain , score 76.9, E-value 2.7e-20 272560002187 Membrane bound YbgT-like protein; Region: YbgT_YccB; pfam08173 272560002188 Cytochrome oxidase subunit II; Region: Cyto_ox_2; cl12219 272560002189 Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294 272560002190 Pfam match to entry PF02322 Cyto_ox_2, Cytochrome oxidase subunit II , score 579.8, E-value 1.2e-171 272560002191 8 probable transmembrane helices predicted for BPSL0501 by TMHMM2.0 at aa 9-31, 77-99, 120-142, 162-184, 205-227, 262-284, 291-313 and 338-360 272560002192 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; cl00562 272560002193 Pfam match to entry PF01654 Bac_Ubq_Cox, Bacterial Cytochrome Ubiquinol Oxidase , score 970.3, E-value 3.2e-289 272560002194 9 probable transmembrane helices predicted for BPSL0502 by TMHMM2.0 at aa 15-37, 56-78, 98-120, 127-149, 188-210, 217-239, 390-412, 425-447 and 470-492 272560002195 1 probable transmembrane helix predicted for BPSL0503 by TMHMM2.0 at aa 40-59 272560002196 RNA polymerase factor sigma-32; Reviewed; Region: PRK06596 272560002197 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 272560002198 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560002199 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560002200 DNA binding residues [nucleotide binding] 272560002201 PS00716 Sigma-70 factors family signature 2. 272560002202 Predicted helix-turn-helix motif with score 1683.000, SD 4.92 at aa 276-297, sequence STLHDLAAEFGVSAERIRQIEA 272560002203 PS00715 Sigma-70 factors family signature 1. 272560002204 Signal peptide predicted for BPSL0505 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.999 between residues 31 and 32; signal peptide 272560002205 Lipid A 3-O-deacylase (PagL); Region: PagL; pfam09411 272560002206 Domain of unknown function (DUF4440); Region: DUF4440; pfam14534 272560002207 2-isopropylmalate synthase; Validated; Region: PRK03739 272560002208 Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942 272560002209 active site 272560002210 catalytic residues [active] 272560002211 metal binding site [ion binding]; metal-binding site 272560002212 Pfam match to entry PF00682 HMGL-like, HMGL-like , score 329.1, E-value 3.3e-96 272560002213 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 272560002214 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 272560002215 Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; cl19151 272560002216 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560002217 Coenzyme A binding pocket [chemical binding]; other site 272560002218 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 56.5, E-value 3.7e-14 272560002219 glycosyl transferase family protein; Provisional; Region: PRK08136 272560002220 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 272560002221 Pfam match to entry PF00591 Glycos_transf_3, Glycosyl transferase, a/b domain , score -84.7, E-value 7e-05 272560002222 Pfam match to entry PF02885 Glycos_trans_3N, Glycosyl transferase, helical bundle domain , score 37.6, E-value 1.8e-08 272560002223 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754 272560002224 formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591 272560002225 [4Fe-4S] binding site [ion binding]; other site 272560002226 molybdopterin cofactor binding site; other site 272560002227 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791 272560002228 molybdopterin cofactor binding site; other site 272560002229 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 272560002230 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 86.9, E-value 2.7e-23 272560002231 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 531.4, E-value 4.1e-157 272560002232 PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 272560002233 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560002234 Small subunit of nitrite reductase (NirD) family, Rieske domain; composed of proteins similar to the Bacillus subtilis small subunit of assimilatory nitrite reductase containing a Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain...; Region: Rieske_NirD_small_Bacillus; cd03530 272560002235 [2Fe-2S] cluster binding site [ion binding]; other site 272560002236 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 66.3, E-value 4.3e-17 272560002237 NAD(P)H-nitrite reductase [Energy production and conversion]; Region: NirB; COG1251 272560002238 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560002239 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560002240 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 272560002241 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 272560002242 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560002243 Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077 272560002244 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain , score 86.2, E-value 4.5e-23 272560002245 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 272560002246 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 83.3, E-value 3.3e-22 272560002247 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 238.7, E-value 5.5e-69 272560002248 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560002249 GST_N family, Class Zeta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Zeta; cd03042 272560002250 C-terminal domain interface [polypeptide binding]; other site 272560002251 GSH binding site (G-site) [chemical binding]; other site 272560002252 putative dimer interface [polypeptide binding]; other site 272560002253 C-terminal, alpha helical domain of Class Zeta Glutathione S-transferases; Region: GST_C_Zeta; cd03191 272560002254 dimer interface [polypeptide binding]; other site 272560002255 N-terminal domain interface [polypeptide binding]; other site 272560002256 maleylacetoacetate (MAA) substrate binding site (H site) [chemical binding]; other site 272560002257 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 54.9, E-value 1.1e-13 272560002258 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 9.4, E-value 0.016 272560002259 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560002260 signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416 272560002261 SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881 272560002262 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 272560002263 P loop; other site 272560002264 GTP binding site [chemical binding]; other site 272560002265 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain , score 360.7, E-value 1e-105 272560002266 PS00300 SRP54-type proteins GTP-binding domain signature. 272560002267 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002268 Pfam match to entry PF02881 SRP54_N, SRP54-type protein, helical bundle domain , score 51.8, E-value 9.6e-13 272560002269 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560002270 S-adenosylmethionine binding site [chemical binding]; other site 272560002271 Pfam match to entry PF03602 Cons_hypoth95, Conserved hypothetical protein 95 , score 208.8, E-value 5.3e-60 272560002272 PS00092 N-6 Adenine-specific DNA methylases signature. 272560002273 Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163 272560002274 active site 272560002275 (T/H)XGH motif; other site 272560002276 Pfam match to entry PF01467 CTP_transf_2, Cytidylyltransferase , score 143.2, E-value 3.1e-40 272560002277 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 272560002278 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 26.6, E-value 1.2e-05 272560002279 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560002280 histidinol-phosphate aminotransferase; Provisional; Region: PRK05387 272560002281 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560002282 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560002283 homodimer interface [polypeptide binding]; other site 272560002284 catalytic residue [active] 272560002285 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 161.5, E-value 9.4e-46 272560002286 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 272560002287 Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462 272560002288 putative active site [active] 272560002289 catalytic residue [active] 272560002290 Pfam match to entry PF01195 Pept_tRNA_hydro, Peptidyl-tRNA hydrolase , score 283.8, E-value 1.5e-82 272560002291 PS01196 Peptidyl-tRNA hydrolase signature 2. 272560002292 PS01195 Peptidyl-tRNA hydrolase signature 1. 272560002293 50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618 272560002294 Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495 272560002295 5S rRNA interface [nucleotide binding]; other site 272560002296 CTC domain interface [polypeptide binding]; other site 272560002297 L16 interface [polypeptide binding]; other site 272560002298 Ribosomal protein TL5, C-terminal domain; Region: Ribosomal_TL5_C; pfam14693 272560002299 Pfam match to entry PF01386 Ribosomal_L25p, Ribosomal L25p family , score 95.9, E-value 5.1e-26 272560002300 ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259 272560002301 N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793 272560002302 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560002303 active site 272560002304 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 132.6, E-value 4.6e-37 272560002305 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 272560002306 PS00114 Phosphoribosyl pyrophosphate synthetase signature. 272560002307 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343 272560002308 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 272560002309 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 272560002310 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein , score 105.4, E-value 7e-29 272560002311 Signal peptide predicted for BPSL0524 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.543 between residues 39 and 40; signal peptide 272560002312 outer membrane lipoprotein LolB; Provisional; Region: lolB; PRK00022 272560002313 Pfam match to entry PF03550 LolB, Outer membrane lipoprotein LolB , score 63.2, E-value 3.6e-16 272560002314 1 probable transmembrane helix predicted for BPSL0524 by TMHMM2.0 at aa 13-35 272560002315 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560002316 Signal peptide predicted for BPSL0525 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 42 and 43; signal peptide 272560002317 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560002318 binding surface 272560002319 TPR motif; other site 272560002320 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560002321 binding surface 272560002322 TPR motif; other site 272560002323 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560002324 binding surface 272560002325 TPR motif; other site 272560002326 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560002327 binding surface 272560002328 TPR motif; other site 272560002329 Pfam match to entry PF00515 TPR, TPR Domain , score 12.6, E-value 0.13 272560002330 Pfam match to entry PF00515 TPR, TPR Domain , score 4.6, E-value 0.94 272560002331 Pfam match to entry PF00515 TPR, TPR Domain , score 3.2, E-value 1.3 272560002332 Pfam match to entry PF00515 TPR, TPR Domain , score 12.6, E-value 0.13 272560002333 formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103 272560002334 N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966 272560002335 DNA binding site [nucleotide binding] 272560002336 catalytic residue [active] 272560002337 H2TH interface [polypeptide binding]; other site 272560002338 putative catalytic residues [active] 272560002339 turnover-facilitating residue; other site 272560002340 intercalation triad [nucleotide binding]; other site 272560002341 8OG recognition residue [nucleotide binding]; other site 272560002342 putative reading head residues; other site 272560002343 Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831 272560002344 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 272560002345 Pfam match to entry PF01149 Fapy_DNA_glyco, Formamidopyrimidine-DNA glycosylase , score 381.4, E-value 5.7e-112 272560002346 PS01242 Formamidopyrimidine-DNA glycosylase signature. 272560002347 A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194 272560002348 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 272560002349 minor groove reading motif; other site 272560002350 helix-hairpin-helix signature motif; other site 272560002351 substrate binding pocket [chemical binding]; other site 272560002352 active site 272560002353 DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431 272560002354 DNA binding and oxoG recognition site [nucleotide binding] 272560002355 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein , score 191.7, E-value 7.5e-55 272560002356 ATP-dependent protease La (LON) domain; Region: LON; cl19481 272560002357 Pfam match to entry PF02190 LON, ATP-dependent protease La (LON) domain , score 9.1, E-value 9.7e-06 272560002358 glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416 272560002359 Pfam match to entry PF03668 UPF0042, Uncharacterised P-loop ATPase family (UPF0042) , score 334.9, E-value 5.9e-98 272560002360 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002361 HPr kinase/phosphorylase; Provisional; Region: PRK05428 272560002362 HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603 272560002363 HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918 272560002364 Hpr binding site; other site 272560002365 active site 272560002366 homohexamer subunit interaction site [polypeptide binding]; other site 272560002367 Pfam match to entry PF02603 Hpr_kinase, HPr Serine kinase , score 149.8, E-value 3.1e-42 272560002368 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002369 PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211 272560002370 active site 272560002371 phosphorylation site [posttranslational modification] 272560002372 Pfam match to entry PF00359 PTS_EIIA_2, Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 , score 65.4, E-value 8e-17 272560002373 PS00372 PTS EIIA domains phosphorylation site signature 2. 272560002374 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 272560002375 30S subunit binding site; other site 272560002376 Pfam match to entry PF02482 Ribosomal_S30, Sigma 54 modulation protein / S30EA ribosomal protein , score 150.4, E-value 2.1e-42 272560002377 RNA polymerase factor sigma-54; Reviewed; Region: PRK05932 272560002378 Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309 272560002379 Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963 272560002380 Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552 272560002381 Pfam match to entry PF00309 Sigma54_factors, Sigma-54 factors family , score 786.1, E-value 9.1e-234 272560002382 PS00718 Sigma-54 factors family signature 2. 272560002383 Predicted helix-turn-helix motif with score 1921.000, SD 5.73 at aa 409-430, sequence LVLREIADTLGLHESTVSRVTT 272560002384 PS00717 Sigma-54 factors family signature 1. 272560002385 PS00041 Bacterial regulatory proteins, araC family signature. 272560002386 ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137 272560002387 ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218 272560002388 Walker A/P-loop; other site 272560002389 ATP binding site [chemical binding]; other site 272560002390 Q-loop/lid; other site 272560002391 ABC transporter signature motif; other site 272560002392 Walker B; other site 272560002393 D-loop; other site 272560002394 H-loop/switch region; other site 272560002395 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 207.7, E-value 1.1e-59 272560002396 PS00211 ABC transporters family signature. 272560002397 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002398 Signal peptide predicted for BPSL0535 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.994 between residues 39 and 40; signal peptide 272560002399 lipopolysaccharide transport periplasmic protein LptA; Region: outer_YhbN_LptA; TIGR03002 272560002400 OstA-like protein; Region: OstA; pfam03968 272560002401 Pfam match to entry PF03968 OstA, OstA-like protein , score 57.5, E-value 1.9e-14 272560002402 Signal peptide predicted for BPSL0536 by SignalP 2.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.878 between residues 20 and 21; signal peptide 272560002403 Lipopolysaccharide-assembly, LptC-related; Region: LptC; pfam06835 272560002404 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560002405 active site 272560002406 motif I; other site 272560002407 motif II; other site 272560002408 D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892 272560002409 KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014 272560002410 putative active site [active] 272560002411 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein. These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604 272560002412 Pfam match to entry PF00571 CBS, CBS domain , score 49.6, E-value 4.4e-12 272560002413 Pfam match to entry PF00571 CBS, CBS domain , score 39.3, E-value 5.8e-09 272560002414 Pfam match to entry PF01380 SIS, SIS domain , score 140.5, E-value 1.9e-39 272560002415 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 272560002416 putative cation:proton antiport protein; Provisional; Region: PRK10669 272560002417 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 272560002418 TrkA-N domain; Region: TrkA_N; pfam02254 272560002419 TrkA-C domain; Region: TrkA_C; pfam02080 272560002420 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 75.6, E-value 6.8e-20 272560002421 12 probable transmembrane helices predicted for BPSL0539 by TMHMM2.0 at aa 5-22, 29-51, 56-78, 85-107, 117-139, 152-174, 184-201, 221-243, 274-293, 296-318, 328-350 and 357-379 272560002422 Pfam match to entry PF02254 TrkA-N, TrkA-N domain , score 73.4, E-value 3.1e-19 272560002423 Pfam match to entry PF02080 TrkA-C, TrkA-C domain , score 25.1, E-value 0.0001 272560002424 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560002425 active site 272560002426 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 145.4, E-value 6.5e-41 272560002427 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 272560002428 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560002429 Signal peptide predicted for BPSL0541 by SignalP 2.0 HMM (Signal peptide probabilty 0.827) with cleavage site probability 0.445 between residues 23 and 24; signal peptide 272560002430 4 probable transmembrane helices predicted for BPSL0541 by TMHMM2.0 at aa 37-59, 69-91, 112-134 and 149-171 272560002431 Pfam match to entry PF01810 LysE, LysE type translocator , score 81.3, E-value 1.3e-21 272560002432 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_hydrolase_3; cd03676 272560002433 nudix motif; other site 272560002434 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 27.6, E-value 1.9e-05 272560002435 formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027 272560002436 N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875 272560002437 Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648 272560002438 putative active site [active] 272560002439 putative substrate binding site [chemical binding]; other site 272560002440 putative cosubstrate binding site; other site 272560002441 catalytic site [active] 272560002442 PS00284 Serpins signature. 272560002443 Pfam match to entry PF01842 ACT, ACT domain , score 27.9, E-value 1.5e-05 272560002444 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 144.7, E-value 1.1e-40 272560002445 Domain of unknown function DUF20; Region: UPF0118; cl00465 272560002446 7 probable transmembrane helices predicted for BPSL0544 by TMHMM2.0 at aa 27-49, 70-92, 156-178, 212-231, 241-258, 263-285 and 312-334 272560002447 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 272560002448 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 272560002449 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 272560002450 ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271 272560002451 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 120.3, E-value 2.4e-33 272560002452 PS00211 ABC transporters family signature. 272560002453 PS00190 Cytochrome c family heme-binding site signature. 272560002454 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002455 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 11.1, E-value 4.9e-07 272560002456 PS00211 ABC transporters family signature. 272560002457 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002458 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560002459 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560002460 putative substrate translocation pore; other site 272560002461 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -62.7, E-value 1.3e-05 272560002462 12 probable transmembrane helices predicted for BPSL0546 by TMHMM2.0 at aa 21-43, 53-75, 87-104, 109-131, 143-165, 170-192, 213-235, 250-272, 279-298, 302-319, 340-362 and 366-388 272560002463 Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629 272560002464 SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496 272560002465 dimer interface [polypeptide binding]; other site 272560002466 ssDNA binding site [nucleotide binding]; other site 272560002467 tetramer (dimer of dimers) interface [polypeptide binding]; other site 272560002468 Pfam match to entry PF00436 SSB, Single-strand binding protein family , score 223.8, E-value 1.6e-64 272560002469 PS00735 Single-strand binding protein family signature 1. 272560002470 PS00736 Single-strand binding protein family signature 2. 272560002471 Genomic island GI 3 272560002472 Restriction endonuclease; Region: Mrr_cat; cl19295 272560002473 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560002474 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560002475 non-specific DNA binding site [nucleotide binding]; other site 272560002476 salt bridge; other site 272560002477 sequence-specific DNA binding site [nucleotide binding]; other site 272560002478 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560002479 non-specific DNA binding site [nucleotide binding]; other site 272560002480 salt bridge; other site 272560002481 sequence-specific DNA binding site [nucleotide binding]; other site 272560002482 Helix-turn-helix domain; Region: HTH_31; pfam13560 272560002483 Predicted helix-turn-helix motif with score 1371.000, SD 3.86 at aa 25-46, sequence ESLVSWAARLGVSVPTLMRIEA 272560002484 PAAR motif; Region: PAAR_motif; pfam05488 272560002485 Glycine zipper; Region: Gly-zipper_Omp; pfam13488 272560002486 1 probable transmembrane helix predicted for BPSL0555 by TMHMM2.0 at aa 264-286 272560002487 Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112 272560002488 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560002489 non-specific DNA binding site [nucleotide binding]; other site 272560002490 salt bridge; other site 272560002491 sequence-specific DNA binding site [nucleotide binding]; other site 272560002492 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 27.2, E-value 2.4e-05 272560002493 Predicted helix-turn-helix motif with score 1738.000, SD 5.11 at aa 46-67, sequence LSTSSMAERAGISKKTLYRLEQ 272560002494 HipA N-terminal domain; Region: Couple_hipA; cl11853 272560002495 Signal peptide predicted for BPSL0561 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.556 between residues 32 and 33; signal peptide 272560002496 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560002497 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560002498 non-specific DNA binding site [nucleotide binding]; other site 272560002499 salt bridge; other site 272560002500 sequence-specific DNA binding site [nucleotide binding]; other site 272560002501 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 54.5, E-value 1.5e-13 272560002502 Predicted helix-turn-helix motif with score 1597.000, SD 4.63 at aa 22-43, sequence LTQAAVAEQIDVDAETVSRFER 272560002503 GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cd00719 272560002504 GIY-YIG motif/motif A; other site 272560002505 active site 272560002506 catalytic site [active] 272560002507 metal binding site [ion binding]; metal-binding site 272560002508 Domain of unknown function (DUF4145); Region: DUF4145; pfam13643 272560002509 RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646 272560002510 putative active site [active] 272560002511 putative NTP binding site [chemical binding]; other site 272560002512 putative nucleic acid binding site [nucleotide binding]; other site 272560002513 Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424 272560002514 active site 272560002515 catalytic triad [active] 272560002516 Predicted helix-turn-helix motif with score 1014.000, SD 2.64 at aa 713-734, sequence LPFALVAQQLNPNPRRFGVWLA 272560002517 Pfam match to entry PF00078 rvt, Reverse transcriptase (RNA-dependent DNA polymerase) , score 18.6, E-value 3.6e-05 272560002518 AAA domain; Region: AAA_23; pfam13476 272560002519 Walker A/P-loop; other site 272560002520 ATP binding site [chemical binding]; other site 272560002521 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 272560002522 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002523 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 272560002524 Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120 272560002525 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 272560002526 active site 272560002527 ATP binding site [chemical binding]; other site 272560002528 substrate binding site [chemical binding]; other site 272560002529 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 272560002530 Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930 272560002531 generic binding surface I; other site 272560002532 1 probable transmembrane helix predicted for BPSL0571 by TMHMM2.0 at aa 597-619 272560002533 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560002534 Signal peptide predicted for BPSL0573 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.817 between residues 26 and 27; signal peptide 272560002535 Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cd00306 272560002536 active site 272560002537 catalytic residues [active] 272560002538 Pfam match to entry PF00082 Peptidase_S8, Subtilase , score -60.0, E-value 1.3e-07 272560002539 PS00138 Serine proteases, subtilase, serine active site. 272560002540 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4688 272560002541 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 272560002542 active site 272560002543 catalytic residues [active] 272560002544 DNA binding site [nucleotide binding] 272560002545 Int/Topo IB signature motif; other site 272560002546 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -15.9, E-value 0.0026 272560002547 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 272560002548 active site 272560002549 catalytic residues [active] 272560002550 Int/Topo IB signature motif; other site 272560002551 DNA binding site [nucleotide binding] 272560002552 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 5.1, E-value 6.8e-05 272560002553 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002554 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 272560002555 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560002556 Pfam match to entry PF01738 DLH, Dienelactone hydrolase , score 127.8, E-value 1.3e-35 272560002557 Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333 272560002558 RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646 272560002559 putative active site [active] 272560002560 putative NTP binding site [chemical binding]; other site 272560002561 putative nucleic acid binding site [nucleotide binding]; other site 272560002562 RT_Bac_retron_I: Reverse transcriptases (RTs) in bacterial retrotransposons or retrons. The polymerase reaction of this enzyme leads to the production of a unique RNA-DNA complex called msDNA (multicopy single-stranded (ss)DNA) in which a small ssDNA...; Region: RT_Bac_retron_I; cd01646 272560002563 putative active site [active] 272560002564 putative NTP binding site [chemical binding]; other site 272560002565 putative nucleic acid binding site [nucleotide binding]; other site 272560002566 Pfam match to entry PF00078 rvt, Reverse transcriptase (RNA-dependent DNA polymerase) , score 23.1, E-value 2e-06 272560002567 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002568 Signal peptide predicted for BPSL0584 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.938 between residues 21 and 22; signal peptide 272560002569 PS00041 Bacterial regulatory proteins, araC family signature. 272560002570 3 probable transmembrane helices predicted for BPSL0584 by TMHMM2.0 at aa 156-178, 215-237 and 247-269 272560002571 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560002572 active site 272560002573 DNA binding site [nucleotide binding] 272560002574 Int/Topo IB signature motif; other site 272560002575 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 17.8, E-value 7.5e-06 272560002576 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002577 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599 272560002578 Pfam match to entry PF02627 CMD, Carboxymuconolactone decarboxylase , score 72.3, E-value 6.8e-19 272560002579 Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534 272560002580 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; Region: VCBS; pfam13517 272560002581 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; Region: VCBS; pfam13517 272560002582 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; Region: VCBS; pfam13517 272560002583 Insecticide toxin TcdB middle/N-terminal region; Region: TcdB_toxin_midN; pfam12256 272560002584 Insecticide toxin TcdB middle/C-terminal region; Region: TcdB_toxin_midC; pfam12255 272560002585 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 272560002586 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 272560002587 Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436 272560002588 5 probable transmembrane helices predicted for BPSL0590 by TMHMM2.0 at aa 1711-1733, 1740-1759, 1774-1796, 1809-1831 and 1851-1873 272560002589 Tetratricopeptide repeat; Region: TPR_12; pfam13424 272560002590 Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060 272560002591 phosphopeptide binding site; other site 272560002592 Pfam match to entry PF00498 FHA, FHA domain , score 77.8, E-value 1.5e-20 272560002593 Predicted helix-turn-helix motif with score 1159.000, SD 3.13 at aa 243-264, sequence IELDVLARMLGLDESHINVQIH 272560002594 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 272560002595 active site 272560002596 ATP binding site [chemical binding]; other site 272560002597 substrate binding site [chemical binding]; other site 272560002598 TOMM system kinase/cyclase fusion protein; Region: TOMM_kin_cyc; TIGR03903 272560002599 activation loop (A-loop); other site 272560002600 Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967 272560002601 metal binding site [ion binding]; metal-binding site 272560002602 AAA ATPase domain; Region: AAA_16; pfam13191 272560002603 Pfam match to entry PF00069 pkinase, Protein kinase domain , score 170.8, E-value 1.5e-48 272560002604 PS00108 Serine/Threonine protein kinases active-site signature. 272560002605 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002606 ribosomal natural product, two-chain TOMM family; Region: RNP_Burkhold; TIGR03795 272560002607 ribosomal natural product, two-chain TOMM family; Region: RNP_Burkhold; TIGR03795 272560002608 bacteriocin biosynthesis cyclodehydratase domain; Region: cyclo_dehyd_2; TIGR03882 272560002609 YcaO-like family; Region: YcaO; pfam02624 272560002610 Pfam match to entry PF02624 DUF181, Uncharacterized ACR, COG1944 , score 36.9, E-value 4.3e-12 272560002611 aldolase II superfamily protein; Provisional; Region: PRK07044 272560002612 intersubunit interface [polypeptide binding]; other site 272560002613 active site 272560002614 Zn2+ binding site [ion binding]; other site 272560002615 Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain , score 180.1, E-value 2.3e-51 272560002616 Signal peptide predicted for BPSL0602 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.438 between residues 33 and 34; signal peptide 272560002617 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560002618 metal binding site [ion binding]; metal-binding site 272560002619 active site 272560002620 I-site; other site 272560002621 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560002622 2 probable transmembrane helices predicted for BPSL0602 by TMHMM2.0 at aa 4-21 and 166-188 272560002623 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 156.6, E-value 2.7e-44 272560002624 Pfam match to entry PF00563 EAL, EAL domain , score 249.7, E-value 2.6e-72 272560002625 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 272560002626 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 272560002627 8 probable transmembrane helices predicted for BPSL0603 by TMHMM2.0 at aa 7-29, 80-102, 115-137, 168-190, 216-238, 295-317, 324-346 and 382-404 272560002628 Pfam match to entry PF01943 Polysacc_synt, Polysaccharide biosynthesis protein , score 141.3, E-value 1.1e-39 272560002629 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560002630 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560002631 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 49.3, E-value 5.6e-12 272560002632 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 272560002633 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 272560002634 Substrate binding site; other site 272560002635 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 272560002636 Pfam match to entry PF01050 MannoseP_isomer, Mannose-6-phosphate isomerase , score 393.7, E-value 1.1e-115 272560002637 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 278.3, E-value 6.6e-81 272560002638 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560002639 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560002640 This family is most closely related to the GT1 family of glycosyltransferases. wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804 272560002641 putative ADP-binding pocket [chemical binding]; other site 272560002642 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 123.9, E-value 1.9e-34 272560002643 active site 272560002644 PAP2 superfamily; Region: PAP2; pfam01569 272560002645 Pfam match to entry PF01569 PAP2, PAP2 superfamily , score 37.8, E-value 1.6e-08 272560002646 6 probable transmembrane helices predicted for BPSL0608 by TMHMM2.0 at aa 13-30, 37-59, 64-86, 99-121, 125-147 and 199-221 272560002647 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560002648 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560002649 Walker A motif; other site 272560002650 ATP binding site [chemical binding]; other site 272560002651 Walker B motif; other site 272560002652 arginine finger; other site 272560002653 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560002654 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 421.7, E-value 4.2e-124 272560002655 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560002656 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560002657 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 46.9, E-value 2.9e-11 272560002658 Predicted helix-turn-helix motif with score 1966.000, SD 5.88 at aa 426-447, sequence GRLAGTARELGISRATLYRWME 272560002659 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560002660 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560002661 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560002662 PS00216 Sugar transport proteins signature 1. 272560002663 Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250 272560002664 Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703 272560002665 Pfam match to entry PF00703 Glyco_hydro_2, Glycosyl hydrolases family 2, immunoglobulin-like beta-sandwich domain , score -13.5, E-value 0.034 272560002666 Domain of unknown function (DUF1839); Region: DUF1839; pfam08893 272560002667 Gly_His_Pro_Ser_Thr_tRNA synthetase class II core domain. This domain is the core catalytic domain of tRNA synthetases of the subgroup containing glycyl, histidyl, prolyl, seryl and threonyl tRNA synthetases. It is primarily responsible for ATP-dependent...; Region: Gly_His_Pro_Ser_Thr_tRS_core; cd00670 272560002668 dimer interface [polypeptide binding]; other site 272560002669 motif 1; other site 272560002670 active site 272560002671 motif 2; other site 272560002672 motif 3; other site 272560002673 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560002674 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560002675 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560002676 active site 272560002677 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560002678 active site 272560002679 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 16.2, E-value 3.6e-05 272560002680 acyl carrier protein; Provisional; Region: PRK07081 272560002681 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 30.4, E-value 2.6e-06 272560002682 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560002683 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560002684 ligand binding site [chemical binding]; other site 272560002685 flexible hinge region; other site 272560002686 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 272560002687 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560002688 Cyclic nucleotide-monophosphate binding domain; Region: cNMP; smart00100 272560002689 ligand binding site [chemical binding]; other site 272560002690 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 272560002691 non-specific DNA interactions [nucleotide binding]; other site 272560002692 DNA binding site [nucleotide binding] 272560002693 sequence specific DNA binding site [nucleotide binding]; other site 272560002694 putative cAMP binding site [chemical binding]; other site 272560002695 Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023 272560002696 CoA-binding domain; Region: CoA_binding_3; pfam13727 272560002697 Bacterial sugar transferase; Region: Bac_transf; pfam02397 272560002698 5 probable transmembrane helices predicted for BPSL0618 by TMHMM2.0 at aa 13-35, 50-72, 84-101, 116-138 and 287-309 272560002699 Pfam match to entry PF02397 Bact_transf, Bacterial sugar transferase , score 139.7, E-value 3.3e-39 272560002700 polysaccharide export protein Wza; Provisional; Region: PRK15078 272560002701 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 272560002702 SLBB domain; Region: SLBB; pfam10531 272560002703 Pfam match to entry PF02563 Poly_export, Polysaccharide biosynthesis/export protein , score 25.2, E-value 5.5e-09 272560002704 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 272560002705 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560002706 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 122.9, E-value 3.8e-34 272560002707 Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505 272560002708 Signal peptide predicted for BPSL0622 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 23 and 24; signal peptide 272560002709 CHRD domain; Region: CHRD; pfam07452 272560002710 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560002711 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560002712 PS01173 Lipolytic enzymes G-D-X-G family, histidine active site. 272560002713 EcsC protein family; Region: EcsC; pfam12787 272560002714 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002715 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560002716 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560002717 putative substrate translocation pore; other site 272560002718 14 probable transmembrane helices predicted for BPSL0625 by TMHMM2.0 at aa 38-60, 75-97, 106-128, 138-160, 167-189, 194-216, 229-251, 256-275, 295-317, 332-354, 361-383, 388-410, 430-452 and 508-530 272560002719 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -119.9, E-value 0.0012 272560002720 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560002721 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 272560002722 putative DNA binding site [nucleotide binding]; other site 272560002723 putative Zn2+ binding site [ion binding]; other site 272560002724 Pfam match to entry PF01047 MarR, MarR family , score 87.0, E-value 2.6e-23 272560002725 intracellular protease, PfpI family; Region: PfpI; TIGR01382 272560002726 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_1; cd03169 272560002727 conserved cys residue [active] 272560002728 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 193.3, E-value 2.5e-55 272560002729 Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616 272560002730 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Bacterial Cryptic D-Serine Dehydratase; Region: PLPDE_III_cryptic_DSD; cd06818 272560002731 dimer interface [polypeptide binding]; other site 272560002732 active site 272560002733 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560002734 substrate binding site [chemical binding]; other site 272560002735 catalytic residue [active] 272560002736 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560002737 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560002738 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560002739 putative active site [active] 272560002740 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 35.6, E-value 2e-09 272560002741 Predicted helix-turn-helix motif with score 982.000, SD 2.53 at aa 44-65, sequence ASIGALAARADVSVATVTRFAK 272560002742 Pfam match to entry PF01380 SIS, SIS domain , score 64.1, E-value 2e-16 272560002743 N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653 272560002744 D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297 272560002745 active site 272560002746 putative substrate binding pocket [chemical binding]; other site 272560002747 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 272560002748 homotrimer interaction site [polypeptide binding]; other site 272560002749 putative active site [active] 272560002750 Pfam match to entry PF01042 UPF0076, YjgF family , score 107.6, E-value 1.5e-29 272560002751 7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792 272560002752 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term; Region: QueF_N; pfam14819 272560002753 Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780 272560002754 Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I , score 36.4, E-value 4.2e-08 272560002755 threonine dehydratase; Reviewed; Region: PRK09224 272560002756 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 272560002757 tetramer interface [polypeptide binding]; other site 272560002758 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560002759 catalytic residue [active] 272560002760 First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906 272560002761 putative Ile/Val binding site [chemical binding]; other site 272560002762 Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907 272560002763 putative Ile/Val binding site [chemical binding]; other site 272560002764 Pfam match to entry PF00585 Thr_dehydrat_C, C-terminal regulatory domain of Threonine dehydratase , score 148.8, E-value 6.4e-42 272560002765 Pfam match to entry PF00585 Thr_dehydrat_C, C-terminal regulatory domain of Threonine dehydratase , score 145.8, E-value 4.9e-41 272560002766 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 348.2, E-value 5.8e-102 272560002767 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 272560002768 Protein of unknown function (DUF3683); Region: DUF3683; pfam12447 272560002769 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560002770 FAD binding domain; Region: FAD_binding_4; pfam01565 272560002771 FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913 272560002772 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560002773 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 272560002774 Cysteine-rich domain; Region: CCG; pfam02754 272560002775 Domain of unknown function (DUF3400); Region: DUF3400; pfam11880 272560002776 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 133.7, E-value 2.2e-37 272560002777 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 6.4, E-value 1.9e-06 272560002778 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002779 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560002780 PS00190 Cytochrome c family heme-binding site signature. 272560002781 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560002782 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 17.3, E-value 0.0016 272560002783 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537 272560002784 nucleotide binding site/active site [active] 272560002785 HIT family signature motif; other site 272560002786 catalytic residue [active] 272560002787 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3536 272560002788 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226 272560002789 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560002790 S-adenosylmethionine binding site [chemical binding]; other site 272560002791 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560002792 Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase , score 408.3, E-value 4.7e-120 272560002793 PS01183 ubiE/COQ5 methyltransferase signature 1. 272560002794 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4395 272560002795 Tim44-like domain; Region: Tim44; pfam04280 272560002796 2 probable transmembrane helices predicted for BPSL0638 by TMHMM2.0 at aa 51-73 and 77-99 272560002797 SCP-2 sterol transfer family; Region: SCP2; cl01225 272560002798 putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750 272560002799 2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982 272560002800 Pfam match to entry PF03109 ABC1, ABC1 family , score 160.8, E-value 1.5e-45 272560002801 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560002802 S-adenosylmethionine binding site [chemical binding]; other site 272560002803 Zinc ribbon domain; Region: Zn-ribbon_8; cl00993 272560002804 Uncharacterized conserved protein [Function unknown]; Region: COG2928 272560002805 2 probable transmembrane helices predicted for BPSL0643 by TMHMM2.0 at aa 9-31 and 51-73 272560002806 aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476 272560002807 EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317 272560002808 dimer interface [polypeptide binding]; other site 272560002809 anticodon binding site; other site 272560002810 Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777 272560002811 homodimer interface [polypeptide binding]; other site 272560002812 motif 1; other site 272560002813 active site 272560002814 motif 2; other site 272560002815 GAD domain; Region: GAD; pfam02938 272560002816 motif 3; other site 272560002817 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain , score 92.0, E-value 7.7e-25 272560002818 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N) , score 34.6, E-value 7.3e-15 272560002819 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560002820 Pfam match to entry PF02938 GAD, GAD domain , score 153.3, E-value 2.8e-43 272560002821 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560002822 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664 272560002823 nudix motif; other site 272560002824 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 64.2, E-value 1.8e-16 272560002825 Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110 272560002826 PLD-like domain; Region: PLDc_2; pfam13091 272560002827 putative active site [active] 272560002828 catalytic site [active] 272560002829 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 272560002830 PLD-like domain; Region: PLDc_2; pfam13091 272560002831 putative active site [active] 272560002832 catalytic site [active] 272560002833 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 15.4, E-value 0.029 272560002834 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 17.2, E-value 0.016 272560002835 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560002836 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560002837 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 45.3, E-value 8.7e-11 272560002838 Predicted helix-turn-helix motif with score 1038.000, SD 2.72 at aa 27-48, sequence LTIGLLAERMQMSKSGVFAHFG 272560002839 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 272560002840 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 272560002841 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560002842 active site 272560002843 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 272560002844 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 58.2, E-value 1.1e-14 272560002845 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 192.8, E-value 3.6e-55 272560002846 Signal peptide predicted for BPSL0649 by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.781 between residues 28 and 29; signal peptide 272560002847 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism]; Region: FadB; COG1250 272560002848 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560002849 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560002850 Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024 272560002851 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560002852 substrate binding site [chemical binding]; other site 272560002853 oxyanion hole (OAH) forming residues; other site 272560002854 trimer interface [polypeptide binding]; other site 272560002855 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 93.5, E-value 2.8e-25 272560002856 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 45.3, E-value 8.7e-11 272560002857 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 17.2, E-value 1.4e-09 272560002858 acetyl-CoA acetyltransferase; Provisional; Region: PRK09052 272560002859 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560002860 dimer interface [polypeptide binding]; other site 272560002861 active site 272560002862 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 321.9, E-value 4.8e-94 272560002863 PS00098 Thiolases acyl-enzyme intermediate signature. 272560002864 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 222.4, E-value 4.3e-64 272560002865 PS00737 Thiolases signature 2. 272560002866 PS00099 Thiolases active site. 272560002867 enoyl-CoA hydratase; Provisional; Region: PRK06688 272560002868 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560002869 substrate binding site [chemical binding]; other site 272560002870 oxyanion hole (OAH) forming residues; other site 272560002871 trimer interface [polypeptide binding]; other site 272560002872 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cl18948 272560002873 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 151.7, E-value 8.1e-43 272560002874 FdhD/NarQ family; Region: FdhD-NarQ; cl00659 272560002875 Pfam match to entry PF02634 FdhD-NarQ, FdhD/NarQ family , score 238.6, E-value 5.9e-69 272560002876 conserved hypothetical protein; Region: nitr_red_assoc; TIGR02664 272560002877 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 272560002878 Pfam match to entry PF01662 Acyl-CoA_hydro, Cytosolic long-chain acyl-CoA thioester hydrolase , score 110.1, E-value 2.8e-30 272560002879 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560002880 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265 272560002881 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560002882 Walker A/P-loop; other site 272560002883 ATP binding site [chemical binding]; other site 272560002884 Q-loop/lid; other site 272560002885 ABC transporter signature motif; other site 272560002886 Walker B; other site 272560002887 D-loop; other site 272560002888 H-loop/switch region; other site 272560002889 6 probable transmembrane helices predicted for BPSL0655 by TMHMM2.0 at aa 36-58, 78-100, 166-188, 193-215, 273-295 and 310-332 272560002890 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 119.6, E-value 3.8e-33 272560002891 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 222.9, E-value 3.1e-64 272560002892 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002893 PS00211 ABC transporters family signature. 272560002894 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208 272560002895 NTP_transferase_like_1 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_1; cd06422 272560002896 Substrate binding site; other site 272560002897 metal-binding site 272560002898 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 41.2, E-value 6.3e-11 272560002899 PS00092 N-6 Adenine-specific DNA methylases signature. 272560002900 Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only]; Region: COG3178 272560002901 Phosphotransferase enzyme family; Region: APH; pfam01636 272560002902 Signal peptide predicted for BPSL0658 by SignalP 2.0 HMM (Signal peptide probabilty 0.893) with cleavage site probability 0.780 between residues 39 and 40; signal peptide 272560002903 Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452 272560002904 Organic solvent tolerance protein; Region: OstA_C; pfam04453 272560002905 Signal peptide predicted for BPSL0659 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.817 between residues 29 and 30; signal peptide 272560002906 peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770 272560002907 SurA N-terminal domain; Region: SurA_N; pfam09312 272560002908 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560002909 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560002910 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain , score 57.9, E-value 1.4e-14 272560002911 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain , score 118.0, E-value 1.2e-32 272560002912 4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK01909 272560002913 16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274 272560002914 Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylase , score 198.8, E-value 5.5e-57 272560002915 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560002916 EamA-like transporter family; Region: EamA; pfam00892 272560002917 EamA-like transporter family; Region: EamA; pfam00892 272560002918 10 probable transmembrane helices predicted for BPSL0662 by TMHMM2.0 at aa 13-35, 45-63, 76-98, 103-125, 138-155, 165-187, 200-222, 232-254, 261-280 and 284-306 272560002919 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 67.3, E-value 2.2e-17 272560002920 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 50.5, E-value 2.3e-12 272560002921 Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233 272560002922 dimer interface [polypeptide binding]; other site 272560002923 active site 272560002924 metal binding site [ion binding]; metal-binding site 272560002925 glutathione binding site [chemical binding]; other site 272560002926 PS00934 Glyoxalase I signature 1. 272560002927 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 149.8, E-value 3.1e-42 272560002928 Protein of unknown function DUF45; Region: DUF45; pfam01863 272560002929 Pfam match to entry PF01863 DUF45, Protein of unknown function DUF45 , score 59.8, E-value 3.8e-15 272560002930 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 272560002931 putative acyl-acceptor binding pocket; other site 272560002932 Pfam match to entry PF01553 Acyltransferase, Acyltransferase , score 116.7, E-value 2.9e-32 272560002933 1 probable transmembrane helix predicted for BPSL0665 by TMHMM2.0 at aa 7-29 272560002934 D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942 272560002935 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560002936 active site 272560002937 motif I; other site 272560002938 motif II; other site 272560002939 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 7.1, E-value 0.0022 272560002940 glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233 272560002941 Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092 272560002942 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 272560002943 Pfam match to entry PF02092 tRNA_synt_2f, Glycyl-tRNA synthetase beta subunit , score 603.2, E-value 1e-178 272560002944 PS00237 G-protein coupled receptors signature. 272560002945 Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733 272560002946 dimer interface [polypeptide binding]; other site 272560002947 motif 1; other site 272560002948 active site 272560002949 motif 2; other site 272560002950 motif 3; other site 272560002951 Pfam match to entry PF02091 tRNA_synt_2e, Glycyl-tRNA synthetase alpha subunit , score 744.5, E-value 2.9e-221 272560002952 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560002953 apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302 272560002954 Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571 272560002955 putative active site [active] 272560002956 catalytic triad [active] 272560002957 putative dimer interface [polypeptide binding]; other site 272560002958 6 probable transmembrane helices predicted for BPSL0669 by TMHMM2.0 at aa 71-93, 108-130, 151-173, 188-210, 254-276 and 538-560 272560002959 Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism]; Region: CorC; COG4535 272560002960 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 272560002961 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 272560002962 Transporter associated domain; Region: CorC_HlyC; smart01091 272560002963 Pfam match to entry PF03471 CorC_HlyC, Transporter associated domain , score 105.5, E-value 6.9e-29 272560002964 Pfam match to entry PF00571 CBS, CBS domain , score 39.5, E-value 5.1e-09 272560002965 Pfam match to entry PF00571 CBS, CBS domain , score 29.9, E-value 4e-06 272560002966 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 272560002967 putative active site pocket [active] 272560002968 dimerization interface [polypeptide binding]; other site 272560002969 putative catalytic residue [active] 272560002970 unkown domain/putative metalloprotease fusion protein; Provisional; Region: PRK13963 272560002971 Pfam match to entry PF02130 UPF0054, Uncharacterized protein family UPF0054 , score 100.0, E-value 3e-27 272560002972 Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702 272560002973 PhoH-like protein; Region: PhoH; pfam02562 272560002974 Pfam match to entry PF02562 PhoH, PhoH-like protein , score 511.8, E-value 3.3e-151 272560002975 PS00017 ATP/GTP-binding site motif A (P-loop). 272560002976 (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325 272560002977 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 272560002978 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560002979 FeS/SAM binding site; other site 272560002980 TRAM domain; Region: TRAM; pfam01938 272560002981 Pfam match to entry PF01938 TRAM, TRAM domain , score 63.7, E-value 2.6e-16 272560002982 PS01278 Uncharacterized protein family UPF0004 signature. 272560002983 Pfam match to entry PF00919 UPF0004, Uncharacterized protein family UPF0004 , score 159.1, E-value 4.9e-45 272560002984 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560002985 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560002986 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560002987 putative effector binding pocket; other site 272560002988 dimerization interface [polypeptide binding]; other site 272560002989 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 150.0, E-value 2.7e-42 272560002990 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 61.4, E-value 1.3e-15 272560002991 PS00044 Bacterial regulatory proteins, lysR family signature. 272560002992 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 9-30, sequence GSLSAAGRKLNLTPAAASARLA 272560002993 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560002994 Signal peptide predicted for BPSL0676 by SignalP 2.0 HMM (Signal peptide probabilty 0.821) with cleavage site probability 0.394 between residues 14 and 15; signal peptide 272560002995 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560002996 putative substrate translocation pore; other site 272560002997 12 probable transmembrane helices predicted for BPSL0676 by TMHMM2.0 at aa 5-27, 42-61, 73-95, 99-121, 128-150, 160-179, 200-222, 237-256, 263-282, 287-309, 329-351 and 355-377 272560002998 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -74.9, E-value 3.4e-05 272560002999 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560003000 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560003001 non-specific DNA binding site [nucleotide binding]; other site 272560003002 salt bridge; other site 272560003003 sequence-specific DNA binding site [nucleotide binding]; other site 272560003004 Cupin domain; Region: Cupin_2; pfam07883 272560003005 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 54.1, E-value 2e-13 272560003006 Predicted helix-turn-helix motif with score 1281.000, SD 3.55 at aa 49-70, sequence LSLDALARLSGVSRAMLAQIES 272560003007 3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353 272560003008 Pfam match to entry PF00926 DHBP_synthase, 3,4-dihydroxy-2-butanone 4-phosphate synthase , score 359.7, E-value 2e-105 272560003009 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 272560003010 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560003011 motif II; other site 272560003012 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 67.0, E-value 2.6e-17 272560003013 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560003014 EamA-like transporter family; Region: EamA; pfam00892 272560003015 9 probable transmembrane helices predicted for BPSL0680 by TMHMM2.0 at aa 29-51, 61-83, 88-110, 114-131, 144-166, 170-192, 204-226, 230-252 and 259-281 272560003016 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 36.6, E-value 3.7e-08 272560003017 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 45.7, E-value 6.8e-11 272560003018 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 272560003019 Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712 272560003020 active site 272560003021 asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536 272560003022 dimer interface [polypeptide binding]; other site 272560003023 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 272560003024 Ligand Binding Site [chemical binding]; other site 272560003025 Molecular Tunnel; other site 272560003026 Pfam match to entry PF00733 Asn_synthase, Asparagine synthase , score 110.1, E-value 2.7e-30 272560003027 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 36.7, E-value 9.2e-11 272560003028 3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427 272560003029 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 272560003030 hinge; other site 272560003031 active site 272560003032 Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) , score 156.4, E-value 3.3e-44 272560003033 5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128 272560003034 This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288 272560003035 putative active site [active] 272560003036 Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) , score -26.4, E-value 1.4e-12 272560003037 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_6; cd06154 272560003038 homotrimer interaction site [polypeptide binding]; other site 272560003039 putative active site [active] 272560003040 Pfam match to entry PF01042 UPF0076, YjgF family , score 43.7, E-value 2.6e-10 272560003041 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) [Carbohydrate transport and metabolism]; Region: GlpF; COG0580 272560003042 Signal peptide predicted for BPSL0686 by SignalP 2.0 HMM (Signal peptide probabilty 0.862) with cleavage site probability 0.719 between residues 23 and 24; signal peptide 272560003043 amphipathic channel; other site 272560003044 Asn-Pro-Ala signature motifs; other site 272560003045 6 probable transmembrane helices predicted for BPSL0686 by TMHMM2.0 at aa 5-27, 40-62, 82-104, 134-153, 163-185 and 212-234 272560003046 Pfam match to entry PF00230 MIP, Major intrinsic protein , score 161.7, E-value 7.9e-46 272560003047 glycerol kinase; Provisional; Region: glpK; PRK00047 272560003048 Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786 272560003049 N- and C-terminal domain interface [polypeptide binding]; other site 272560003050 active site 272560003051 MgATP binding site [chemical binding]; other site 272560003052 catalytic site [active] 272560003053 metal binding site [ion binding]; metal-binding site 272560003054 glycerol binding site [chemical binding]; other site 272560003055 homotetramer interface [polypeptide binding]; other site 272560003056 homodimer interface [polypeptide binding]; other site 272560003057 FBP binding site [chemical binding]; other site 272560003058 protein IIAGlc interface [polypeptide binding]; other site 272560003059 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 300.5, E-value 1.4e-87 272560003060 PS00445 FGGY family of carbohydrate kinases signature 2. 272560003061 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 390.4, E-value 1.1e-114 272560003062 PS00933 FGGY family of carbohydrate kinases signature 1. 272560003063 Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578 272560003064 glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266 272560003065 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score 334.1, E-value 1e-97 272560003066 PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 272560003067 Signal peptide predicted for BPSL0689 by SignalP 2.0 HMM (Signal peptide probabilty 0.839) with cleavage site probability 0.837 between residues 21 and 22; signal peptide 272560003068 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 272560003069 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220 272560003070 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 272560003071 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family , score 311.5, E-value 6.7e-91 272560003072 Predicted helix-turn-helix motif with score 1572.000, SD 4.54 at aa 45-66, sequence VTVDDLAAHFNVTPQTIRRDVN 272560003073 PS00894 Bacterial regulatory proteins, deoR family signature. 272560003074 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 272560003075 Pfam match to entry PF01019 G_glu_transpept, Gamma-glutamyltranspeptidase , score 574.2, E-value 5.3e-170 272560003076 PS00678 Trp-Asp (WD) repeats signature. 272560003077 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 272560003078 dinuclear metal binding motif [ion binding]; other site 272560003079 ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590 272560003080 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 272560003081 ATP binding site [chemical binding]; other site 272560003082 Mg++ binding site [ion binding]; other site 272560003083 motif III; other site 272560003084 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560003085 nucleotide binding region [chemical binding]; other site 272560003086 ATP-binding site [chemical binding]; other site 272560003087 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 119.4, E-value 4.4e-33 272560003088 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 275.7, E-value 4e-80 272560003089 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 272560003090 Predicted helix-turn-helix motif with score 1033.000, SD 2.71 at aa 83-104, sequence TPTRELAAQVEESVRAYSKYVK 272560003091 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003092 Signal peptide predicted for BPSL0696 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.333 between residues 19 and 20; signal peptide 272560003093 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560003094 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560003095 Cytochrome c; Region: Cytochrom_C; pfam00034 272560003096 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 23.5, E-value 0.00011 272560003097 PS00190 Cytochrome c family heme-binding site signature. 272560003098 PS00190 Cytochrome c family heme-binding site signature. 272560003099 PS00190 Cytochrome c family heme-binding site signature. 272560003100 Signal peptide predicted for BPSL0697 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 between residues 31 and 32; signal peptide 272560003101 Cytochrome c; Region: Cytochrom_C; cl11414 272560003102 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560003103 Cytochrome c; Region: Cytochrom_C; cl11414 272560003104 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 10.1, E-value 0.0025 272560003105 PS00190 Cytochrome c family heme-binding site signature. 272560003106 PS00190 Cytochrome c family heme-binding site signature. 272560003107 Signal peptide predicted for BPSL0698 by SignalP 2.0 HMM (Signal peptide probabilty 0.713) with cleavage site probability 0.464 between residues 24 and 25; signal peptide 272560003108 Copper resistance protein D; Region: CopD; cl00563 272560003109 8 probable transmembrane helices predicted for BPSL0698 by TMHMM2.0 at aa 13-35, 56-78, 98-120, 127-149, 169-191, 204-226, 241-263 and 284-306 272560003110 PS00211 ABC transporters family signature. 272560003111 galactonate dehydratase; Provisional; Region: PRK14017 272560003112 D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325 272560003113 putative active site pocket [active] 272560003114 putative metal binding site [ion binding]; other site 272560003115 Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain , score 279.1, E-value 3.7e-81 272560003116 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 272560003117 Pfam match to entry PF02746 MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain , score 167.7, E-value 1.2e-47 272560003118 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 272560003119 Uncharacterized conserved protein [Function unknown]; Region: COG3791 272560003120 Signal peptide predicted for BPSL0701 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.157 between residues 39 and 40; signal peptide 272560003121 Domain of unknown function (DUF4377); Region: DUF4377; pfam14302 272560003122 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 272560003123 active site 272560003124 metal binding site [ion binding]; metal-binding site 272560003125 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 47.9, E-value 1.5e-11 272560003126 MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300 272560003127 Signal peptide predicted for BPSL0703 by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.417 between residues 23 and 24; signal peptide 272560003128 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 272560003129 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 272560003130 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 272560003131 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560003132 Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176 272560003133 linker region; other site 272560003134 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560003135 dimer interface [polypeptide binding]; other site 272560003136 phosphorylation site [posttranslational modification] 272560003137 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560003138 ATP binding site [chemical binding]; other site 272560003139 Mg2+ binding site [ion binding]; other site 272560003140 G-X-G motif; other site 272560003141 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 141.7, E-value 8.7e-40 272560003142 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 15.0, E-value 0.0011 272560003143 Pfam match to entry PF03707 SPNTR, Bacterial signalling protein N terminal repeat , score 20.4, E-value 2.2e-06 272560003144 7 probable transmembrane helices predicted for BPSL0703 by TMHMM2.0 at aa 10-32, 44-66, 76-94, 107-126, 141-163, 176-198 and 213-235 272560003145 PS00213 Lipocalin signature. 272560003146 Pfam match to entry PF03707 SPNTR, Bacterial signalling protein N terminal repeat , score 65.9, E-value 5.6e-17 272560003147 Pfam match to entry PF03707 SPNTR, Bacterial signalling protein N terminal repeat , score 84.0, E-value 2.1e-22 272560003148 Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437 272560003149 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560003150 active site 272560003151 phosphorylation site [posttranslational modification] 272560003152 intermolecular recognition site; other site 272560003153 dimerization interface [polypeptide binding]; other site 272560003154 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560003155 Zn2+ binding site [ion binding]; other site 272560003156 Mg2+ binding site [ion binding]; other site 272560003157 Pfam match to entry PF01966 HD, HD domain , score 22.5, E-value 0.00016 272560003158 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 112.3, E-value 6.1e-31 272560003159 Domain of unknown function (DUF4142); Region: DUF4142; pfam13628 272560003160 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560003161 PAS fold; Region: PAS_3; pfam08447 272560003162 putative active site [active] 272560003163 heme pocket [chemical binding]; other site 272560003164 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560003165 dimerization interface [polypeptide binding]; other site 272560003166 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560003167 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560003168 dimer interface [polypeptide binding]; other site 272560003169 putative CheW interface [polypeptide binding]; other site 272560003170 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 330.1, E-value 1.7e-96 272560003171 Pfam match to entry PF00672 HAMP, HAMP domain , score 26.6, E-value 3.9e-05 272560003172 1 probable transmembrane helix predicted for BPSL0706 by TMHMM2.0 at aa 172-194 272560003173 Pfam match to entry PF00785 PAC, PAC motif , score 25.3, E-value 9.3e-05 272560003174 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560003175 FAD binding domain; Region: FAD_binding_4; pfam01565 272560003176 Cholesterol oxidase, substrate-binding; Region: Chol_subst-bind; pfam09129 272560003177 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 65.0, E-value 1.1e-16 272560003178 Probable gene remnant. Similar to internal regions of Escherichia coli aerobic C4-dicarboxylate transport protein DctA SWALL:DCTA_ECOLI (SWALL:P37312) (428 aa) fasta scores: E(): 5.5e-14, 38.02% id in 142 aa, and Ralstonia solanacearum C4-dicarboxylate transport protein 3 rsp0995 or rs02327 SWALL:DTA3_RALSO (SWALL:Q8XR66) (447 aa) fasta scores: E(): 3.7e-14, 38.46% id in 143 aa; transport protein (fragment) 272560003179 2 probable transmembrane helices predicted for BPSL0708 by TMHMM2.0 at aa 27-49 and 97-119 272560003180 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 52.8, E-value 2.8e-14 272560003181 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560003182 dimerization interface [polypeptide binding]; other site 272560003183 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 121.1, E-value 1.4e-33 272560003184 tRNA 2-selenouridine synthase; Provisional; Region: PRK11784 272560003185 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 272560003186 active site residue [active] 272560003187 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003188 1 probable transmembrane helix predicted for BPSL0711 by TMHMM2.0 at aa 44-66 272560003189 Signal peptide predicted for BPSL0712 by SignalP 2.0 HMM (Signal peptide probabilty 0.868) with cleavage site probability 0.501 between residues 24 and 25; signal peptide 272560003190 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 272560003191 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 272560003192 Walker A/P-loop; other site 272560003193 ATP binding site [chemical binding]; other site 272560003194 Q-loop/lid; other site 272560003195 ABC transporter signature motif; other site 272560003196 Walker B; other site 272560003197 D-loop; other site 272560003198 H-loop/switch region; other site 272560003199 C-terminal AAA-associated domain; Region: AAA_assoc_C; pfam09821 272560003200 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 174.6, E-value 1e-49 272560003201 PS00211 ABC transporters family signature. 272560003202 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003203 ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986 272560003204 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560003205 dimer interface [polypeptide binding]; other site 272560003206 conserved gate region; other site 272560003207 putative PBP binding loops; other site 272560003208 ABC-ATPase subunit interface; other site 272560003209 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560003210 dimer interface [polypeptide binding]; other site 272560003211 conserved gate region; other site 272560003212 putative PBP binding loops; other site 272560003213 ABC-ATPase subunit interface; other site 272560003214 12 probable transmembrane helices predicted for BPSL0713 by TMHMM2.0 at aa 67-89, 113-135, 167-189, 231-253, 260-279, 283-305, 379-401, 421-443, 455-477, 487-509, 530-552 and 585-607 272560003215 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 21.8, E-value 0.00043 272560003216 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 31.5, E-value 1.3e-06 272560003217 Possible gene remnant. Similar to the C-terminal region of Mycobacterium tuberculosis hypothetical protein RV2030c rv2030c or mtv018.17c or mt2089 SWALL:O53475 (EMBL:AL021899) (681 aa) fasta scores: E(): 3.9e-62, 44.94% id in 465 aa, and to the full length Neurospora crassa conserved hypothetical protein 13E11.380 SWALL:Q9P6X8 (EMBL:AL353820) (474 aa) fasta scores: E(): 2.4e-33, 36.42% id in 464 aa. Contains a frameshift after codon 304. Frameshift possibly occurs at a polymeric repeat (GCG x4);hypothetical protein (pseudogene) 272560003218 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560003219 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 272560003220 nicotinate phosphoribosyltransferase; Validated; Region: PRK09243 272560003221 Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570 272560003222 active site 272560003223 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560003224 active site 272560003225 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 30.9, E-value 1.9e-06 272560003226 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 272560003227 Transglycosylase; Region: Transgly; cl19357 272560003228 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560003229 1 probable transmembrane helix predicted for BPSL0719 by TMHMM2.0 at aa 21-43 272560003230 Signal peptide predicted for BPSL0720 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.892 between residues 32 and 33; signal peptide 272560003231 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560003232 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560003233 Cytochrome c; Region: Cytochrom_C; pfam00034 272560003234 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 8.0, E-value 0.0042 272560003235 PS00190 Cytochrome c family heme-binding site signature. 272560003236 PS00190 Cytochrome c family heme-binding site signature. 272560003237 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560003238 Signal peptide predicted for BPSL0721 by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.699 between residues 52 and 53; signal peptide 272560003239 3 probable transmembrane helices predicted for BPSL0721 by TMHMM2.0 at aa 22-44, 72-94 and 180-202 272560003240 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 272560003241 cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891 272560003242 Heme-copper oxidase subunit III subfamily. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane; Region: Heme_Cu_Oxidase_III_2; cd02865 272560003243 Subunit I/III interface [polypeptide binding]; other site 272560003244 Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III , score -99.1, E-value 2.6e-11 272560003245 19 probable transmembrane helices predicted for BPSL0722 by TMHMM2.0 at aa 60-82, 102-124, 136-158, 185-207, 228-250, 270-292, 305-327, 342-364, 376-398, 413-435, 447-469, 492-514, 605-622, 627-644, 760-782, 802-821, 834-856, 871-893 and 914-936 272560003246 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score 624.8, E-value 3.2e-185 272560003247 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560003248 Signal peptide predicted for BPSL0723 by SignalP 2.0 HMM (Signal peptide probabilty 0.903) with cleavage site probability 0.339 between residues 39 and 40; signal peptide 272560003249 cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866 272560003250 The cupredoxin domain of Caa3 type Cytochrome c oxidase subunit II; Region: CuRO_CcO_Caa3_II; cd04213 272560003251 oligomer interface [polypeptide binding]; other site 272560003252 CuA binuclear center [ion binding]; other site 272560003253 Cytochrome c; Region: Cytochrom_C; pfam00034 272560003254 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 35.3, E-value 9.3e-08 272560003255 PS00190 Cytochrome c family heme-binding site signature. 272560003256 Pfam match to entry PF00116 COX2, Cytochrome C oxidase subunit II, periplasmic domain , score 62.5, E-value 5.8e-16 272560003257 PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 272560003258 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003259 2 probable transmembrane helices predicted for BPSL0723 by TMHMM2.0 at aa 86-108 and 121-143 272560003260 thiamine pyrophosphate protein; Provisional; Region: PRK08273 272560003261 Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039 272560003262 PYR/PP interface [polypeptide binding]; other site 272560003263 dimer interface [polypeptide binding]; other site 272560003264 tetramer interface [polypeptide binding]; other site 272560003265 TPP binding site [chemical binding]; other site 272560003266 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560003267 Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014 272560003268 TPP-binding site [chemical binding]; other site 272560003269 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 98.1, E-value 1.2e-26 272560003270 PS00187 Thiamine pyrophosphate enzymes signature. 272560003271 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 73.0, E-value 4.2e-19 272560003272 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 186.5, E-value 2.8e-53 272560003273 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 272560003274 Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 3. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_3; cd03328 272560003275 putative active site pocket [active] 272560003276 putative metal binding site [ion binding]; other site 272560003277 Pfam match to entry PF02746 MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain , score 38.4, E-value 1.1e-08 272560003278 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 272560003279 Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain , score 39.0, E-value 6.9e-09 272560003280 Signal peptide predicted for BPSL0726 by SignalP 2.0 HMM (Signal peptide probabilty 0.986) with cleavage site probability 0.886 between residues 22 and 23; signal peptide 272560003281 6 probable transmembrane helices predicted for BPSL0726 by TMHMM2.0 at aa 90-107, 122-141, 153-175, 195-217, 224-246 and 261-278 272560003282 Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618 272560003283 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 272560003284 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560003285 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560003286 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score -194.1, E-value 7.4e-06 272560003287 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560003288 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 272560003289 Protein related to penicillin acylase [General function prediction only]; Region: COG2366 272560003290 Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747 272560003291 active site 272560003292 1 probable transmembrane helix predicted for BPSL0730 by TMHMM2.0 at aa 51-73 272560003293 Pfam match to entry PF01804 Penicil_amidase, Penicillin amidase , score 246.9, E-value 1.9e-71 272560003294 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560003295 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560003296 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 272560003297 putative effector binding pocket; other site 272560003298 putative dimerization interface [polypeptide binding]; other site 272560003299 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 71.3, E-value 1.3e-18 272560003300 Predicted helix-turn-helix motif with score 1115.000, SD 2.98 at aa 101-122, sequence NSFTRAAETLGMPRASVTTIIQ 272560003301 PS00044 Bacterial regulatory proteins, lysR family signature. 272560003302 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 153.9, E-value 1.8e-43 272560003303 Signal peptide predicted for BPSL0732 by SignalP 2.0 HMM (Signal peptide probabilty 0.828) with cleavage site probability 0.729 between residues 27 and 28; signal peptide 272560003304 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560003305 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560003306 dimer interface [polypeptide binding]; other site 272560003307 phosphorylation site [posttranslational modification] 272560003308 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560003309 ATP binding site [chemical binding]; other site 272560003310 Mg2+ binding site [ion binding]; other site 272560003311 G-X-G motif; other site 272560003312 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560003313 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560003314 active site 272560003315 phosphorylation site [posttranslational modification] 272560003316 intermolecular recognition site; other site 272560003317 dimerization interface [polypeptide binding]; other site 272560003318 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 25.7, E-value 5.6e-06 272560003319 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 133.3, E-value 2.8e-37 272560003320 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 53.1, E-value 3.9e-13 272560003321 1 probable transmembrane helix predicted for BPSL0732 by TMHMM2.0 at aa 183-205 272560003322 Signal peptide predicted for BPSL0733 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 30 and 31; signal peptide 272560003323 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 272560003324 BetR domain; Region: BetR; pfam08667 272560003325 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560003326 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560003327 active site 272560003328 phosphorylation site [posttranslational modification] 272560003329 intermolecular recognition site; other site 272560003330 dimerization interface [polypeptide binding]; other site 272560003331 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 1.2, E-value 0.00043 272560003332 Low G+C region, possible genomic island 272560003333 Protein of unknown function (DUF2971); Region: DUF2971; pfam11185 272560003334 2 probable transmembrane helices predicted for BPSL0742 by TMHMM2.0 at aa 19-36 and 40-62 272560003335 Abortive infection C-terminus; Region: Abi_C; pfam14355 272560003336 INT_SG2, DNA breaking-rejoining enzymes, integrase/recombinases subgroup 2, C-terminal catalytic domain. The CD contains mainly predicted integrase/recombinases and phage-related integrases. Some have N-terminal domains, which show little sequence...; Region: INT_SG2_C; cd01184 272560003337 Int/Topo IB signature motif; other site 272560003338 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 17.0, E-value 8.7e-06 272560003339 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain , score 1.4, E-value 0.028 272560003340 Genomic island GI 4 272560003341 Restriction endonuclease; Region: Mrr_cat; cl19295 272560003342 TIGR02680 family protein; Region: TIGR02680 272560003343 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003344 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 272560003345 Weakly similar to the C-terminal regions of Escherichia coli integrase/recombinase XerD or XprB or b2894 SWALL:XERD_ECOLI (SWALL:P21891) (298 aa) fasta scores: E(): 2.2, 26.39% id in 197 aa, and Chlamydia muridarum integrase/recombinase TC0255 SWALL:Q9PL53 (EMBL:AE002292) (301 aa) fasta scores: E(): 0.2, 26.66% id in 135 aa; integrase/recombinase (fragment) 272560003346 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -21.3, E-value 0.0066 272560003347 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560003348 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560003349 non-specific DNA binding site [nucleotide binding]; other site 272560003350 salt bridge; other site 272560003351 sequence-specific DNA binding site [nucleotide binding]; other site 272560003352 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 63.9, E-value 2.3e-16 272560003353 Predicted helix-turn-helix motif with score 1904.000, SD 5.67 at aa 29-50, sequence ISQEELGDRAGLHRTYISQVER 272560003354 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560003355 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 272560003356 active site 272560003357 metal binding site [ion binding]; metal-binding site 272560003358 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 47.8, E-value 1.6e-11 272560003359 Malonate decarboxylase delta subunit (MdcD); Region: ACP; cl06082 272560003360 RNA 2'-phosphotransferase, Tpt1 / KptA family; Region: PTS_2-RNA; pfam01885 272560003361 Pfam match to entry PF01885 DUF60, Domain of unknown function DUF60 , score 200.5, E-value 1.7e-57 272560003362 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560003363 ATP binding site [chemical binding]; other site 272560003364 putative Mg++ binding site [ion binding]; other site 272560003365 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560003366 nucleotide binding region [chemical binding]; other site 272560003367 ATP-binding site [chemical binding]; other site 272560003368 Pfam match to entry PF00176 SNF2_N, SNF2 family N-terminal domain , score -36.0, E-value 8e-08 272560003369 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 58.9, E-value 7e-15 272560003370 PS00092 N-6 Adenine-specific DNA methylases signature. 272560003371 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560003372 ATP-binding site [chemical binding]; other site 272560003373 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 16.9, E-value 0.00055 272560003374 Domain of unknown function (DUF1998); Region: DUF1998; pfam09369 272560003375 Putative catalytic domain of uncharacterized phospholipase D-like proteins; Region: PLDc_unchar4; cd09132 272560003376 PLD-like domain; Region: PLDc_2; pfam13091 272560003377 putative active site [active] 272560003378 putative catalytic site [active] 272560003379 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 30.4, E-value 2.7e-06 272560003380 Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416 272560003381 Predicted ATPase [General function prediction only]; Region: COG5293 272560003382 Protein of unknown function (DUF3732); Region: DUF3732; pfam12532 272560003383 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003384 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560003385 active site 272560003386 Int/Topo IB signature motif; other site 272560003387 DNA binding site [nucleotide binding] 272560003388 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -34.9, E-value 0.071 272560003389 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560003390 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560003391 putative substrate translocation pore; other site 272560003392 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 109.1, E-value 5.4e-30 272560003393 12 probable transmembrane helices predicted for BPSL0773 by TMHMM2.0 at aa 24-46, 61-83, 96-118, 128-150, 163-185, 195-217, 252-274, 289-311, 318-335, 459-481, 494-516 and 526-544 272560003394 PS00217 Sugar transport proteins signature 2. 272560003395 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 272560003396 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560003397 HAMP domain; Region: HAMP; pfam00672 272560003398 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560003399 dimer interface [polypeptide binding]; other site 272560003400 phosphorylation site [posttranslational modification] 272560003401 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920 272560003402 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560003403 ATP binding site [chemical binding]; other site 272560003404 Mg2+ binding site [ion binding]; other site 272560003405 G-X-G motif; other site 272560003406 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 127.3, E-value 1.8e-35 272560003407 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 65.5, E-value 7.1e-17 272560003408 Pfam match to entry PF00672 HAMP, HAMP domain , score 37.9, E-value 1.6e-08 272560003409 2 probable transmembrane helices predicted for BPSL0774 by TMHMM2.0 at aa 54-76 and 207-229 272560003410 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560003411 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560003412 active site 272560003413 phosphorylation site [posttranslational modification] 272560003414 intermolecular recognition site; other site 272560003415 dimerization interface [polypeptide binding]; other site 272560003416 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560003417 DNA binding site [nucleotide binding] 272560003418 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 79.6, E-value 4.2e-21 272560003419 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 144.9, E-value 9.3e-41 272560003420 recombinase A; Provisional; Region: recA; PRK09354 272560003421 RecA is a bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response. RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983 272560003422 hexamer interface [polypeptide binding]; other site 272560003423 Walker A motif; other site 272560003424 ATP binding site [chemical binding]; other site 272560003425 Walker B motif; other site 272560003426 Pfam match to entry PF00154 recA, recA bacterial DNA recombination protein , score 825.4, E-value 1.3e-245 272560003427 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003428 PS00321 recA signature. 272560003429 recombination regulator RecX; Provisional; Region: recX; PRK14136 272560003430 Pfam match to entry PF02631 RecX, RecX family , score 23.6, E-value 8.2e-07 272560003431 Protein of unknown function (DUF2889); Region: DUF2889; pfam11136 272560003432 succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696 272560003433 ATP-grasp domain; Region: ATP-grasp_2; pfam08442 272560003434 CoA-ligase; Region: Ligase_CoA; pfam00549 272560003435 Pfam match to entry PF02222 ATP-grasp, ATP-grasp domain , score 160.5, E-value 1.9e-45 272560003436 PS00063 Aldo/keto reductase active site signature. 272560003437 Pfam match to entry PF00549 ligase-CoA, CoA-ligase , score 245.2, E-value 5.9e-71 272560003438 PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 272560003439 succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678 272560003440 CoA binding domain; Region: CoA_binding; smart00881 272560003441 CoA-ligase; Region: Ligase_CoA; pfam00549 272560003442 Pfam match to entry PF02629 CoA_binding, CoA binding domain , score 193.0, E-value 3.2e-55 272560003443 Pfam match to entry PF00549 ligase-CoA, CoA-ligase , score 154.7, E-value 1.1e-43 272560003444 PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 272560003445 PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 272560003446 integral membrane protein, YjbE family; Region: R_switched_YjbE; TIGR03717 272560003447 Pfam match to entry PF03741 TerC, Integral membrane protein TerC family , score 168.9, E-value 5.4e-48 272560003448 5 probable transmembrane helices predicted for BPSL0781 by TMHMM2.0 at aa 44-66, 79-101, 174-196, 203-222 and 237-257 272560003449 Tfp pilus assembly protein, major pilin PilA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilA; COG4969 272560003450 prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532 272560003451 Pilin (bacterial filament); Region: Pilin; pfam00114 272560003452 Pfam match to entry PF00114 pilin, Pilin (bacterial filament) , score 71.9, E-value 8.6e-19 272560003453 Signal peptide predicted for BPSL0783 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.868 between residues 25 and 26; signal peptide 272560003454 Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307 272560003455 O-Antigen ligase; Region: Wzy_C; pfam04932 272560003456 Domain of unknown function (DUF3366); Region: DUF3366; pfam11846 272560003457 12 probable transmembrane helices predicted for BPSL0783 by TMHMM2.0 at aa 13-35, 45-67, 74-96, 106-125, 138-160, 182-204, 211-229, 233-250, 263-285, 364-386, 393-415 and 435-457 272560003458 hypothetical protein; Provisional; Region: PRK11667 272560003459 Signal peptide predicted for BPSL0784 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.992 between residues 26 and 27; signal peptide 272560003460 Signal peptide predicted for BPSL0785 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.597 between residues 28 and 29; signal peptide 272560003461 Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; cl10048 272560003462 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560003463 MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420 272560003464 trimer interface [polypeptide binding]; other site 272560003465 dimer interface [polypeptide binding]; other site 272560003466 putative active site [active] 272560003467 Pfam match to entry PF01967 MoaC, MoaC family , score 276.9, E-value 1.7e-80 272560003468 Signal peptide predicted for BPSL0787 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.982 between residues 25 and 26; signal peptide 272560003469 Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783 272560003470 Peptidase family M48; Region: Peptidase_M48; pfam01435 272560003471 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560003472 Protein of unknown function (DUF2946); Region: DUF2944; pfam11161 272560003473 Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429 272560003474 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560003475 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 27.3, E-value 2.4e-05 272560003476 PS00120 Lipases, serine active site. 272560003477 SnoaL-like domain; Region: SnoaL_3; pfam13474 272560003478 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560003479 putative active site [active] 272560003480 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 303.1, E-value 2.2e-88 272560003481 Zinc-finger domain; Region: zf-CHCC; cl01821 272560003482 branched-chain amino acid aminotransferase; Provisional; Region: PRK13357 272560003483 BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557 272560003484 homodimer interface [polypeptide binding]; other site 272560003485 substrate-cofactor binding pocket; other site 272560003486 catalytic residue [active] 272560003487 Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV , score 376.2, E-value 2.2e-110 272560003488 PS00770 Aminotransferases class-IV signature. 272560003489 AzlC protein; Region: AzlC; cl00570 272560003490 6 probable transmembrane helices predicted for BPSL0794 by TMHMM2.0 at aa 20-38, 53-75, 88-110, 138-160, 167-186 and 210-232 272560003491 Pfam match to entry PF03591 AzlC, AzlC protein , score 79.1, E-value 5.7e-21 272560003492 Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437 272560003493 2 probable transmembrane helices predicted for BPSL0795 by TMHMM2.0 at aa 4-26 and 83-105 272560003494 phosphoglycerate kinase; Provisional; Region: pgk; PRK00073 272560003495 substrate binding site [chemical binding]; other site 272560003496 hinge regions; other site 272560003497 ADP binding site [chemical binding]; other site 272560003498 catalytic site [active] 272560003499 Pfam match to entry PF00162 PGK, Phosphoglycerate kinase , score 614.7, E-value 3.4e-182 272560003500 PS00111 Phosphoglycerate kinase signature. 272560003501 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003502 pyruvate kinase; Provisional; Region: PRK05826 272560003503 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288 272560003504 domain interfaces; other site 272560003505 active site 272560003506 Pfam match to entry PF00224 PK, Pyruvate kinase, barrel domain , score 491.4, E-value 4.7e-145 272560003507 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003508 Pfam match to entry PF02887 PK_C, Pyruvate kinase, alpha/beta domain , score 105.9, E-value 5.2e-29 272560003509 Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947 272560003510 intersubunit interface [polypeptide binding]; other site 272560003511 active site 272560003512 zinc binding site [ion binding]; other site 272560003513 Na+ binding site [ion binding]; other site 272560003514 Pfam match to entry PF01116 F_bP_aldolase, Fructose-bisphosphate aldolase class-II , score 561.2, E-value 4.4e-166 272560003515 PS00602 Fructose-bisphosphate aldolase class-II signature 1. 272560003516 PS00806 Fructose-bisphosphate aldolase class-II signature 2. 272560003517 non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414 272560003518 ATP binding site [chemical binding]; other site 272560003519 active site 272560003520 phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional; Region: PRK13959 272560003521 substrate binding site [chemical binding]; other site 272560003522 Pfam match to entry PF01259 SAICAR_synt, SAICAR synthetase , score 424.9, E-value 4.7e-125 272560003523 PS01058 SAICAR synthetase signature 2. 272560003524 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041 272560003525 Pfam match to entry PF00731 AIRC, AIR carboxylase , score 269.3, E-value 3.4e-78 272560003526 phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019 272560003527 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560003528 Pfam match to entry PF02222 ATP-grasp, ATP-grasp domain , score 72.8, E-value 4.7e-19 272560003529 Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009 272560003530 Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481 272560003531 Pfam match to entry PF01300 Sua5_yciO_yrdC, yrdC domain , score 190.7, E-value 1.5e-54 272560003532 PS01147 SUA5/yciO/yrdC family signature. 272560003533 Pfam match to entry PF03481 SUA5, SUA5 domain , score 39.0, E-value 6.8e-09 272560003534 Triacylglycerol lipase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: Triacylglycerol_lipase_like; cd01847 272560003535 active site 272560003536 catalytic triad [active] 272560003537 oxyanion hole [active] 272560003538 Pfam match to entry PF00657 Lipase_GDSL, Lipase/Acylhydrolase with GDSL-like motif , score -2.8, E-value 0.02 272560003539 Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000 272560003540 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116 272560003541 4 probable transmembrane helices predicted for BPSL0804 by TMHMM2.0 at aa 5-27, 58-77, 81-100 and 132-154 272560003542 Signal peptide predicted for BPSL0805 by SignalP 2.0 HMM (Signal peptide probabilty 0.970) with cleavage site probability 0.563 between residues 12 and 13; signal peptide 272560003543 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027 272560003544 D-Ala-D-Ala carboxypeptidase 3 (S13) family; Region: Peptidase_S13; cl17429 272560003545 Pfam match to entry PF02113 Peptidase_S13, D-Ala-D-Ala carboxypeptidase 3 (S13) family , score 257.8, E-value 9.6e-75 272560003546 DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643 272560003547 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560003548 active site 272560003549 phosphorylation site [posttranslational modification] 272560003550 intermolecular recognition site; other site 272560003551 dimerization interface [polypeptide binding]; other site 272560003552 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560003553 DNA binding site [nucleotide binding] 272560003554 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 152.0, E-value 6.6e-43 272560003555 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 95.3, E-value 7.8e-26 272560003556 Signal peptide predicted for BPSL0807 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.639 between residues 33 and 34; signal peptide 272560003557 sensor protein QseC; Provisional; Region: PRK10337 272560003558 HAMP domain; Region: HAMP; pfam00672 272560003559 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560003560 dimer interface [polypeptide binding]; other site 272560003561 phosphorylation site [posttranslational modification] 272560003562 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560003563 ATP binding site [chemical binding]; other site 272560003564 Mg2+ binding site [ion binding]; other site 272560003565 G-X-G motif; other site 272560003566 2 probable transmembrane helices predicted for BPSL0807 by TMHMM2.0 at aa 10-32 and 138-160 272560003567 Pfam match to entry PF00672 HAMP, HAMP domain , score 35.4, E-value 8.4e-08 272560003568 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 59.3, E-value 5.5e-15 272560003569 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 118.3, E-value 9.5e-33 272560003570 Signal peptide predicted for BPSL0808 by SignalP 2.0 HMM (Signal peptide probabilty 0.642) with cleavage site probability 0.522 between residues 26 and 27; signal peptide 272560003571 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 272560003572 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 272560003573 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560003574 protein binding site [polypeptide binding]; other site 272560003575 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560003576 protein binding site [polypeptide binding]; other site 272560003577 Pfam match to entry PF00089 trypsin, Trypsin , score 91.7, E-value 9.7e-25 272560003578 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 67.7, E-value 1.6e-17 272560003579 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 50.4, E-value 2.6e-12 272560003580 Signal peptide predicted for BPSL0809 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 25 and 26; signal peptide 272560003581 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 272560003582 Domain of unknown function (DUF427); Region: DUF427; pfam04248 272560003583 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 272560003584 hydrophobic ligand binding site; other site 272560003585 1 probable transmembrane helix predicted for BPSL0811 by TMHMM2.0 at aa 219-241 272560003586 DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668 272560003587 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560003588 MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361 272560003589 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 83.3, E-value 3.2e-22 272560003590 PS01081 Bacterial regulatory proteins, tetR family signature. 272560003591 Predicted helix-turn-helix motif with score 2122.000, SD 6.41 at aa 32-53, sequence TSLADIAQHAGVTRGAIYWHFA 272560003592 Signal peptide predicted for BPSL0814 by SignalP 2.0 HMM (Signal peptide probabilty 0.689) with cleavage site probability 0.589 between residues 28 and 29; signal peptide 272560003593 multidrug efflux system transporter AcrA; Provisional; Region: PRK15030 272560003594 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560003595 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560003596 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560003597 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 212.2, E-value 5e-61 272560003598 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915 272560003599 Signal peptide predicted for BPSL0815 by SignalP 2.0 HMM (Signal peptide probabilty 0.970) with cleavage site probability 0.751 between residues 25 and 26; signal peptide 272560003600 MMPL family; Region: MMPL; cl14618 272560003601 MMPL family; Region: MMPL; cl14618 272560003602 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1839.6, E-value 0 272560003603 12 probable transmembrane helices predicted for BPSL0815 by TMHMM2.0 at aa 13-35, 340-359, 366-388, 392-414, 438-460, 470-492, 540-559, 869-891, 898-920, 925-947, 968-990 and 1000-1022 272560003604 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003605 Signal peptide predicted for BPSL0816 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.298 between residues 24 and 25; signal peptide 272560003606 copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837 272560003607 Outer membrane efflux protein; Region: OEP; pfam02321 272560003608 Outer membrane efflux protein; Region: OEP; pfam02321 272560003609 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560003610 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 175.2, E-value 7e-50 272560003611 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 184.1, E-value 1.4e-52 272560003612 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560003613 xanthine permease; Region: pbuX; TIGR03173 272560003614 11 probable transmembrane helices predicted for BPSL0817 by TMHMM2.0 at aa 46-68, 75-97, 127-149, 156-178, 193-210, 215-237, 268-290, 343-365, 370-392, 404-421 and 431-453 272560003615 Pfam match to entry PF00860 xan_ur_permease, Permease , score 471.8, E-value 3.7e-139 272560003616 PS01116 Xanthine/uracil permeases family signature. 272560003617 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070 272560003618 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 272560003619 nucleotide binding site [chemical binding]; other site 272560003620 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 172.2, E-value 5.7e-49 272560003621 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 89.0, E-value 6.3e-24 272560003622 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560003623 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560003624 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 272560003625 conserved cys residue [active] 272560003626 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560003627 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.3, E-value 1.1e-08 272560003628 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 30.5, E-value 2.5e-06 272560003629 Predicted helix-turn-helix motif with score 991.000, SD 2.56 at aa 212-233, sequence LSIAQLARRAAMSERNFIRVFV 272560003630 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 30.2, E-value 3.1e-06 272560003631 Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062 272560003632 class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300 272560003633 substrate binding site [chemical binding]; other site 272560003634 catalytic Zn binding site [ion binding]; other site 272560003635 NAD binding site [chemical binding]; other site 272560003636 structural Zn binding site [ion binding]; other site 272560003637 dimer interface [polypeptide binding]; other site 272560003638 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 464.6, E-value 5.3e-137 272560003639 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560003640 Predicted esterase [General function prediction only]; Region: COG0627 272560003641 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187 272560003642 Pfam match to entry PF00756 Esterase, esterase , score 255.6, E-value 4.5e-74 272560003643 ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108 272560003644 ABC-ATPase subunit interface; other site 272560003645 dimer interface [polypeptide binding]; other site 272560003646 putative PBP binding regions; other site 272560003647 Pfam match to entry PF00950 ABC-3, ABC 3 transport family , score 144.1, E-value 1.6e-40 272560003648 7 probable transmembrane helices predicted for BPSL0822 by TMHMM2.0 at aa 10-30, 43-65, 85-107, 120-142, 171-193, 214-236 and 241-258 272560003649 ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121 272560003650 ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235 272560003651 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 150.5, E-value 1.8e-42 272560003652 PS00211 ABC transporters family signature. 272560003653 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003654 Signal peptide predicted for BPSL0824 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.972 between residues 22 and 23; signal peptide 272560003655 ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803 272560003656 Metal binding protein TroA_b. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: TroA_b; cd01020 272560003657 metal binding site [ion binding]; metal-binding site 272560003658 Pfam match to entry PF01297 SBP_bac_9, Periplasmic solute binding protein family , score 45.8, E-value 6.3e-11 272560003659 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 272560003660 metal binding site 2 [ion binding]; metal-binding site 272560003661 putative DNA binding helix; other site 272560003662 metal binding site 1 [ion binding]; metal-binding site 272560003663 dimer interface [polypeptide binding]; other site 272560003664 structural Zn2+ binding site [ion binding]; other site 272560003665 Pfam match to entry PF01475 FUR, Ferric uptake regulator family , score 4.5, E-value 6.6e-06 272560003666 sorbitol dehydrogenase; Provisional; Region: PRK07067 272560003667 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560003668 NAD(P) binding site [chemical binding]; other site 272560003669 active site 272560003670 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 285.0, E-value 6.1e-83 272560003671 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560003672 PS00061 Short-chain dehydrogenases/reductases family signature. 272560003673 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 272560003674 substrate binding site [chemical binding]; other site 272560003675 ATP binding site [chemical binding]; other site 272560003676 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 151.6, E-value 9e-43 272560003677 Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211 272560003678 Signal peptide predicted for BPSL0829 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.699 between residues 28 and 29; signal peptide 272560003679 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560003680 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 272560003681 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 298.0, E-value 7.4e-87 272560003682 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560003683 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560003684 dimer interface [polypeptide binding]; other site 272560003685 conserved gate region; other site 272560003686 putative PBP binding loops; other site 272560003687 ABC-ATPase subunit interface; other site 272560003688 6 probable transmembrane helices predicted for BPSL0830 by TMHMM2.0 at aa 33-55, 92-114, 121-143, 173-195, 231-253 and 279-301 272560003689 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 57.3, E-value 2.1e-14 272560003690 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560003691 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 272560003692 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560003693 dimer interface [polypeptide binding]; other site 272560003694 conserved gate region; other site 272560003695 putative PBP binding loops; other site 272560003696 ABC-ATPase subunit interface; other site 272560003697 6 probable transmembrane helices predicted for BPSL0831 by TMHMM2.0 at aa 27-49, 81-103, 120-142, 157-176, 197-219 and 251-273 272560003698 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 53.2, E-value 3.7e-13 272560003699 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560003700 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560003701 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 272560003702 active site 272560003703 motif I; other site 272560003704 motif II; other site 272560003705 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 87.8, E-value 1.5e-23 272560003706 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 272560003707 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 272560003708 Walker A/P-loop; other site 272560003709 ATP binding site [chemical binding]; other site 272560003710 Q-loop/lid; other site 272560003711 ABC transporter signature motif; other site 272560003712 Walker B; other site 272560003713 D-loop; other site 272560003714 H-loop/switch region; other site 272560003715 TOBE domain; Region: TOBE; pfam03459 272560003716 TOBE domain; Region: TOBE_2; pfam08402 272560003717 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 223.3, E-value 2.3e-64 272560003718 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003719 PS00211 ABC transporters family signature. 272560003720 Pfam match to entry PF03459 TOBE, TOBE domain , score 43.6, E-value 2.8e-10 272560003721 Signal peptide predicted for BPSL0834 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.623 between residues 29 and 30; signal peptide 272560003722 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 272560003723 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560003724 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560003725 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_7; cd08476 272560003726 putative effector binding pocket; other site 272560003727 putative dimerization interface [polypeptide binding]; other site 272560003728 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 180.6, E-value 1.7e-51 272560003729 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 79.2, E-value 5.4e-21 272560003730 PS00044 Bacterial regulatory proteins, lysR family signature. 272560003731 Predicted helix-turn-helix motif with score 1362.000, SD 3.83 at aa 17-38, sequence RSFVAAARALGVSASAVGKRIA 272560003732 Beta-lactamase; Region: Beta-lactamase; pfam00144 272560003733 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560003734 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560003735 putative substrate translocation pore; other site 272560003736 12 probable transmembrane helices predicted for BPSL0837 by TMHMM2.0 at aa 23-45, 60-82, 89-111, 115-137, 149-171, 181-200, 221-243, 258-280, 287-309, 313-335, 347-366 and 371-390 272560003737 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -101.9, E-value 0.00029 272560003738 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 272560003739 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 272560003740 Predicted helix-turn-helix motif with score 1214.000, SD 3.32 at aa 23-44, sequence DTQNEIAEKLQVSRPVAQRLVA 272560003741 Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808 272560003742 N- and C-terminal domain interface [polypeptide binding]; other site 272560003743 D-xylulose kinase; Region: XylB; TIGR01312 272560003744 active site 272560003745 MgATP binding site [chemical binding]; other site 272560003746 catalytic site [active] 272560003747 metal binding site [ion binding]; metal-binding site 272560003748 xylulose binding site [chemical binding]; other site 272560003749 homodimer interface [polypeptide binding]; other site 272560003750 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 196.4, E-value 3e-56 272560003751 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 319.7, E-value 2.2e-93 272560003752 PS00933 FGGY family of carbohydrate kinases signature 1. 272560003753 Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246 272560003754 Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232 272560003755 Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125 272560003756 Pfam match to entry PF01232 Mannitol_dh, Mannitol dehydrogenase , score 516.0, E-value 1.9e-152 272560003757 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560003758 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560003759 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560003760 dimerization interface [polypeptide binding]; other site 272560003761 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 107.5, E-value 1.6e-29 272560003762 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 101.8, E-value 8.9e-28 272560003763 PS00044 Bacterial regulatory proteins, lysR family signature. 272560003764 Predicted helix-turn-helix motif with score 1976.000, SD 5.92 at aa 14-35, sequence GSLGRAADALHVTQPALSRILK 272560003765 benzoylformate decarboxylase; Reviewed; Region: PRK07092 272560003766 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560003767 PYR/PP interface [polypeptide binding]; other site 272560003768 dimer interface [polypeptide binding]; other site 272560003769 TPP binding site [chemical binding]; other site 272560003770 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560003771 Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of...; Region: TPP_BFDC; cd02002 272560003772 TPP-binding site [chemical binding]; other site 272560003773 dimer interface [polypeptide binding]; other site 272560003774 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 171.2, E-value 1.1e-48 272560003775 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 28.9, E-value 1.2e-07 272560003776 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 111.4, E-value 1.2e-30 272560003777 PS00187 Thiamine pyrophosphate enzymes signature. 272560003778 Salicylaldehyde dehydrogenase, DoxF-like; Region: ALDH_SaliADH; cd07105 272560003779 NAD(P) binding site [chemical binding]; other site 272560003780 catalytic residues [active] 272560003781 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 453.4, E-value 1.3e-133 272560003782 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560003783 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 272560003784 Signal peptide predicted for BPSL0844 by SignalP 2.0 HMM (Signal peptide probabilty 0.781) with cleavage site probability 0.524 between residues 20 and 21; signal peptide 272560003785 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 272560003786 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 272560003787 Pfam match to entry PF03721 UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain , score 31.1, E-value 5.7e-08 272560003788 Pfam match to entry PF02558 ApbA, Ketopantoate reductase PanE/ApbA , score 141.2, E-value 1.2e-39 272560003789 benzoate transport; Region: 2A0115; TIGR00895 272560003790 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560003791 putative substrate translocation pore; other site 272560003792 12 probable transmembrane helices predicted for BPSL0845 by TMHMM2.0 at aa 49-71, 86-108, 115-137, 141-163, 175-197, 202-224, 287-309, 324-343, 350-369, 373-392, 413-435 and 439-461 272560003793 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 81.2, E-value 1.4e-21 272560003794 PS00216 Sugar transport proteins signature 1. 272560003795 tryptophan 2,3-dioxygenase; Region: trp_2_3_diox; TIGR03036 272560003796 Pfam match to entry PF03301 Trp_dioxygenase, Tryptophan 2,3-dioxygenase , score 344.6, E-value 6.9e-101 272560003797 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560003798 Kynureninase [Amino acid transport and metabolism]; Region: COG3844 272560003799 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560003800 catalytic residue [active] 272560003801 Putative cyclase; Region: Cyclase; cl00814 272560003802 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560003803 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560003804 putative DNA binding site [nucleotide binding]; other site 272560003805 putative Zn2+ binding site [ion binding]; other site 272560003806 AsnC family; Region: AsnC_trans_reg; pfam01037 272560003807 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 116.5, E-value 3.3e-32 272560003808 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 272560003809 Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain , score 197.3, E-value 1.5e-56 272560003810 methionine sulfoxide reductase A; Provisional; Region: PRK14054 272560003811 Pfam match to entry PF01625 PMSR, Peptide methionine sulfoxide reductase , score 281.0, E-value 9.6e-82 272560003812 Protein of unknown function DUF72; Region: DUF72; pfam01904 272560003813 Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230 272560003814 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560003815 S-adenosylmethionine binding site [chemical binding]; other site 272560003816 Pfam match to entry PF02353 CMAS, Cyclopropane-fatty-acyl-phospholipid synthase , score 224.9, E-value 7.8e-65 272560003817 pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679 272560003818 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243 272560003819 Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; Region: PNPOx_C; pfam10590 272560003820 Pfam match to entry PF01243 Pyridox_oxidase, Pyridoxamine 5'-phosphate oxidase , score 377.9, E-value 6.9e-111 272560003821 PS01064 Pyridoxamine 5'-phosphate oxidase signature. 272560003822 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179 272560003823 Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755 272560003824 putative ATP binding site [chemical binding]; other site 272560003825 putative substrate interface [chemical binding]; other site 272560003826 Pfam match to entry PF00899 ThiF, ThiF family , score 151.6, E-value 9.1e-43 272560003827 Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118 272560003828 ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956 272560003829 Tetratricopeptide repeat; Region: TPR_20; pfam14561 272560003830 Pfam match to entry PF00085 thiored, Thioredoxin , score 104.8, E-value 1.1e-28 272560003831 PS00194 Thioredoxin family active site. 272560003832 Pirin-related protein [General function prediction only]; Region: COG1741 272560003833 Pirin; Region: Pirin; pfam02678 272560003834 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 272560003835 Pfam match to entry PF02678 DUF209, Uncharacterized BCR, YhhW family COG1741 , score -72.7, E-value 4.1e-06 272560003836 O-acetylserine/cysteine export protein; Provisional; Region: PRK11453 272560003837 EamA-like transporter family; Region: EamA; pfam00892 272560003838 EamA-like transporter family; Region: EamA; pfam00892 272560003839 10 probable transmembrane helices predicted for BPSL0858 by TMHMM2.0 at aa 54-71, 81-99, 108-130, 135-157, 164-181, 185-207, 216-238, 253-275, 282-304 and 309-330 272560003840 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 44.9, E-value 1.2e-10 272560003841 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 75.6, E-value 6.9e-20 272560003842 Signal peptide predicted for BPSL0859 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.953 between residues 48 and 49; signal peptide 272560003843 AMIN domain; Region: AMIN; pfam11741 272560003844 N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696 272560003845 active site 272560003846 metal binding site [ion binding]; metal-binding site 272560003847 Pfam match to entry PF01520 Amidase_3, N-acetylmuramoyl-L-alanine amidase , score 214.4, E-value 1.1e-61 272560003848 Predicted ATPase or kinase [General function prediction only]; Region: COG0802 272560003849 Pfam match to entry PF02367 UPF0079, Uncharacterised P-loop hydrolase UPF0079 , score 134.3, E-value 1.4e-37 272560003850 PS00017 ATP/GTP-binding site motif A (P-loop). 272560003851 epoxyqueuosine reductase; Region: TIGR00276 272560003852 Domain of unknown function (DUF1730); Region: DUF1730; pfam08331 272560003853 4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484 272560003854 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 14.9, E-value 0.00081 272560003855 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560003856 Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350 272560003857 The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445 272560003858 DNA binding site [nucleotide binding] 272560003859 active site 272560003860 Pfam match to entry PF01035 Methyltransf_1, 6-O-methylguanine DNA methyltransferase, DNA binding domain , score 112.8, E-value 4.3e-31 272560003861 Predicted helix-turn-helix motif with score 1100.000, SD 2.93 at aa 107-128, sequence LTYGQIAKQIGSAPRAVGQACG 272560003862 PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 272560003863 site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283 272560003864 XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798 272560003865 active site 272560003866 Int/Topo IB signature motif; other site 272560003867 Pfam match to entry PF02899 Phage_integr_N, Phage integrase, N-terminal SAM-like domain , score 71.3, E-value 1.3e-18 272560003868 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 205.6, E-value 5.1e-59 272560003869 Predicted helix-turn-helix motif with score 1086.000, SD 2.89 at aa 265-286, sequence RHAQQADVRVHLSPHTLRHAFA 272560003870 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 272560003871 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560003872 acyl-activating enzyme (AAE) consensus motif; other site 272560003873 AMP binding site [chemical binding]; other site 272560003874 active site 272560003875 CoA binding site [chemical binding]; other site 272560003876 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 388.4, E-value 4.8e-114 272560003877 PS00455 AMP-binding domain signature. 272560003878 This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002 272560003879 putative deacylase active site [active] 272560003880 putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220 272560003881 6 probable transmembrane helices predicted for BPSL0866 by TMHMM2.0 at aa 26-48, 75-94, 103-122, 137-159, 164-183 and 187-201 272560003882 Pfam match to entry PF02660 DUF205, Domain of unknown function DUF , score 209.4, E-value 3.4e-60 272560003883 Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740 272560003884 UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046 272560003885 FAD binding domain; Region: FAD_binding_4; pfam01565 272560003886 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873 272560003887 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 14.3, E-value 2.5e-05 272560003888 Pfam match to entry PF02873 MurB_C, UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain , score 151.3, E-value 1.1e-42 272560003889 ornithine carbamoyltransferase; Provisional; Region: PRK00779 272560003890 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 272560003891 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 272560003892 Pfam match to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain , score 197.5, E-value 1.4e-56 272560003893 Pfam match to entry PF02729 OTCace_N, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain , score 230.5, E-value 1.6e-66 272560003894 PS00097 Aspartate and ornithine carbamoyltransferases signature. 272560003895 Protein of unknown function (DUF3579); Region: DUF3579; pfam12112 272560003896 30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239 272560003897 Pfam match to entry PF01649 Ribosomal_S20p, Ribosomal protein S20 , score 105.6, E-value 6.3e-29 272560003898 Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728 272560003899 MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123 272560003900 Pfam match to entry PF03023 MVIN, Virulence factor MVIN , score 510.7, E-value 7.3e-151 272560003901 12 probable transmembrane helices predicted for BPSL0872 by TMHMM2.0 at aa 167-189, 204-226, 233-255, 260-279, 317-339, 354-376, 389-408, 428-450, 463-485, 490-509, 522-544 and 559-581 272560003902 Uncharacterized conserved protein [Function unknown]; Region: COG2912 272560003903 Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369 272560003904 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217 272560003905 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560003906 NAD(P) binding site [chemical binding]; other site 272560003907 active site 272560003908 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 144.2, E-value 1.5e-40 272560003909 PS00061 Short-chain dehydrogenases/reductases family signature. 272560003910 adenylate kinase; Reviewed; Region: adk; PRK00279 272560003911 Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428 272560003912 AMP-binding site [chemical binding]; other site 272560003913 ATP-AMP (Ap5A)-binding site [chemical binding]; other site 272560003914 Pfam match to entry PF00406 adenylatekinase, Adenylate kinase , score 420.7, E-value 8.5e-124 272560003915 PS00113 Adenylate kinase signature. 272560003916 CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517 272560003917 Ligand binding site; other site 272560003918 oligomer interface; other site 272560003919 Pfam match to entry PF02348 CTP_transf_3, Cytidylyltransferase , score 244.9, E-value 7.5e-71 272560003920 Uncharacterized conserved protein [Function unknown]; Region: COG2835 272560003921 Pfam match to entry PF03966 DUF343, Protein of unknown function (DUF343) , score 101.6, E-value 1e-27 272560003922 tetraacyldisaccharide 4'-kinase; Provisional; Region: PRK01906 272560003923 Signal peptide predicted for BPS0878 by SignalP 2.0 HMM (Signal peptide probability: 1.000) with cleavage site probability: 0.797 between residues 22 and 23; signal peptide 272560003924 Pfam match to entry PF02606 LpxK, Tetraacyldisaccharide-1-P 4'-kinase , score 244.3, E-value 1.1e-70 272560003925 exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286 272560003926 ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489 272560003927 generic binding surface II; other site 272560003928 generic binding surface I; other site 272560003929 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain , score 39.4, E-value 5.5e-09 272560003930 Pfam match to entry PF02601 Exonuc_VII_L, Exonuclease VII, large subunit , score 131.1, E-value 1.4e-36 272560003931 superoxide dismutase; Provisional; Region: PRK10543 272560003932 Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081 272560003933 Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777 272560003934 Pfam match to entry PF00081 sodfe, Iron/manganese superoxide dismutases, alpha-hairpin domain , score 178.1, E-value 9.4e-51 272560003935 Predicted helix-turn-helix motif with score 1020.000, SD 2.66 at aa 8-29, sequence LPYAEDALAPHISQETIQFHYG 272560003936 Pfam match to entry PF02777 sodfe_C, Iron/manganese superoxide dismutases, C-terminal domain , score 248.2, E-value 7.2e-72 272560003937 PS00088 Manganese and iron superoxide dismutases signature. 272560003938 Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059 272560003939 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 272560003940 Chromate transporter; Region: Chromate_transp; pfam02417 272560003941 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 3.1, E-value 1.1e-05 272560003942 10 probable transmembrane helices predicted for BPSL0882 by TMHMM2.0 at aa 12-34, 84-106, 113-135, 150-181, 202-224, 239-261, 268-290, 300-322, 335-357 and 377-399 272560003943 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 78.2, E-value 1.1e-20 272560003944 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560003945 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560003946 ligand binding site [chemical binding]; other site 272560003947 flexible hinge region; other site 272560003948 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 272560003949 putative switch regulator; other site 272560003950 non-specific DNA interactions [nucleotide binding]; other site 272560003951 DNA binding site [nucleotide binding] 272560003952 sequence specific DNA binding site [nucleotide binding]; other site 272560003953 putative cAMP binding site [chemical binding]; other site 272560003954 Predicted helix-turn-helix motif with score 1544.000, SD 4.45 at aa 180-201, sequence LSQERLGAMLSLTRQTANQLLK 272560003955 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 73.9, E-value 2.2e-19 272560003956 Protein of unknown function (DUF962); Region: DUF962; cl01879 272560003957 4 probable transmembrane helices predicted for BPSL0884 by TMHMM2.0 at aa 21-40, 45-67, 97-116 and 131-153 272560003958 2-dehydropantoate 2-reductase; Provisional; Region: PRK08229 272560003959 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 272560003960 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 272560003961 Pfam match to entry PF02558 ApbA, Ketopantoate reductase PanE/ApbA , score 74.0, E-value 2.1e-19 272560003962 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560003963 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560003964 S-adenosylmethionine binding site [chemical binding]; other site 272560003965 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560003966 Pfam match to entry PF00563 EAL, EAL domain , score -4.6, E-value 2.2e-10 272560003967 putative transporter; Provisional; Region: PRK10504 272560003968 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560003969 putative substrate translocation pore; other site 272560003970 14 probable transmembrane helices predicted for BPSL0888 by TMHMM2.0 at aa 17-39, 54-76, 83-105, 109-131, 143-165, 170-192, 205-222, 232-254, 261-283, 298-320, 333-355, 365-387, 400-422 and 437-459 272560003971 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 16.4, E-value 3.5e-05 272560003972 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 272560003973 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560003974 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 272560003975 DNA binding residues [nucleotide binding] 272560003976 Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate...; Region: citrate_synt_like_2; cd06102 272560003977 dimer interface [polypeptide binding]; other site 272560003978 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 272560003979 active site 272560003980 oxalacetate/citrate binding site [chemical binding]; other site 272560003981 citrylCoA binding site [chemical binding]; other site 272560003982 coenzyme A binding site [chemical binding]; other site 272560003983 catalytic triad [active] 272560003984 Pfam match to entry PF00285 citrate_synt, Citrate synthase , score -1.9, E-value 3e-12 272560003985 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 272560003986 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560003987 DNA-binding site [nucleotide binding]; DNA binding site 272560003988 UTRA domain; Region: UTRA; pfam07702 272560003989 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 75.6, E-value 6.8e-20 272560003990 PS00043 Bacterial regulatory proteins, gntR family signature. 272560003991 Predicted helix-turn-helix motif with score 1047.000, SD 2.75 at aa 46-67, sequence PSERLLAESLGVSRITARKAIA 272560003992 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 272560003993 active site 272560003994 catalytic tetrad [active] 272560003995 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase , score 206.1, E-value 3.5e-59 272560003996 elongation factor G; Reviewed; Region: PRK00007 272560003997 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 272560003998 G1 box; other site 272560003999 putative GEF interaction site [polypeptide binding]; other site 272560004000 GTP/Mg2+ binding site [chemical binding]; other site 272560004001 Switch I region; other site 272560004002 G2 box; other site 272560004003 G3 box; other site 272560004004 Switch II region; other site 272560004005 G4 box; other site 272560004006 G5 box; other site 272560004007 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 272560004008 Elongation Factor G, domain II; Region: EFG_II; pfam14492 272560004009 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 272560004010 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 272560004011 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus , score 171.4, E-value 1e-48 272560004012 Pfam match to entry PF03764 EFG_IV, Elongation factor G, domain IV , score 235.8, E-value 4.1e-68 272560004013 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 96.7, E-value 2.9e-26 272560004014 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 367.1, E-value 1.2e-107 272560004015 PS00301 GTP-binding elongation factors signature. 272560004016 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004017 Signal peptide predicted for BPSL0894 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 34 and 35; signal peptide 272560004018 Uncharacterized ACR, COG1430; Region: DUF192; pfam02643 272560004019 Pfam match to entry PF02643 DUF192, Uncharacterized ACR, COG1430 , score 70.3, E-value 2.7e-18 272560004020 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 272560004021 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 272560004022 active site 272560004023 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 86.4, E-value 3.8e-23 272560004024 PS01149 Rsu family of pseudouridine synthase signature. 272560004025 isocitrate dehydrogenase; Reviewed; Region: PRK07006 272560004026 Pfam match to entry PF00180 isodh, Isocitrate/isopropylmalate dehydrogenase , score 499.2, E-value 2e-147 272560004027 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 272560004028 Signal peptide predicted for BPSL0897 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 25 and 26; signal peptide 272560004029 Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132 272560004030 Cupredoxin superfamily; Region: Cupredoxin; cl19115 272560004031 The second cupredoxin domain of a multicopper oxidase McoC and similar proteins; Region: CuRO_2_McoC_like; cd13881 272560004032 Domain 1 interface [polypeptide binding]; other site 272560004033 Domain 3 interface [polypeptide binding]; other site 272560004034 Cupredoxin superfamily; Region: Cupredoxin; cl19115 272560004035 Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase , score 1.7, E-value 0.0053 272560004036 PS00080 Multicopper oxidases signature 2. 272560004037 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 272560004038 DNA-binding site [nucleotide binding]; DNA binding site 272560004039 RNA-binding motif; other site 272560004040 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain , score 149.8, E-value 3.1e-42 272560004041 PS00352 'Cold-shock' DNA-binding domain signature. 272560004042 Uncharacterized conserved protein [Function unknown]; Region: COG2127 272560004043 ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639 272560004044 Clp amino terminal domain; Region: Clp_N; pfam02861 272560004045 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560004046 Walker A motif; other site 272560004047 ATP binding site [chemical binding]; other site 272560004048 Walker B motif; other site 272560004049 arginine finger; other site 272560004050 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560004051 Walker A motif; other site 272560004052 ATP binding site [chemical binding]; other site 272560004053 Walker B motif; other site 272560004054 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 272560004055 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain , score 62.2, E-value 7.5e-16 272560004056 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 40.9, E-value 1.8e-09 272560004057 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004058 PS00870 Chaperonins clpA/B signature 1. 272560004059 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 22.4, E-value 1.4e-06 272560004060 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004061 PS00871 Chaperonins clpA/B signature 2. 272560004062 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 272560004063 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 272560004064 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 387.4, E-value 9.1e-114 272560004065 12 probable transmembrane helices predicted for BPSL0900 by TMHMM2.0 at aa 21-43, 47-69, 100-122, 137-159, 172-194, 209-231, 252-271, 291-313, 334-356, 366-385, 405-427 and 431-453 272560004066 PS00218 Amino acid permeases signature. 272560004067 1 probable transmembrane helix predicted for BPSL0901 by TMHMM2.0 at aa 30-52 272560004068 Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4705 272560004069 Signal peptide predicted for BPSL0902 by SignalP 2.0 HMM (Signal peptide probabilty 0.625) with cleavage site probability 0.481 between residues 22 and 23; signal peptide 272560004070 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560004071 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560004072 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560004073 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560004074 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 51.9, E-value 9.3e-13 272560004075 7 probable transmembrane helices predicted for BPSL0902 by TMHMM2.0 at aa 35-57, 64-83, 88-110, 130-149, 154-176, 183-205 and 215-237 272560004076 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 32.1, E-value 8.2e-07 272560004077 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 56.3, E-value 4.4e-14 272560004078 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 272560004079 trimer interface [polypeptide binding]; other site 272560004080 active site 272560004081 Pfam match to entry PF00692 dUTPase, dUTPase , score 159.1, E-value 5e-45 272560004082 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579 272560004083 Flavoprotein; Region: Flavoprotein; cl19190 272560004084 DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127 272560004085 Pfam match to entry PF02441 Flavoprotein, Flavoprotein , score 151.4, E-value 1e-42 272560004086 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004087 lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376 272560004088 Pfam match to entry PF01252 Peptidase_A8, Signal peptidase (SPase) II , score 178.9, E-value 5.3e-51 272560004089 5 probable transmembrane helices predicted for BPSL0905 by TMHMM2.0 at aa 10-26, 33-55, 70-92, 99-121 and 134-156 272560004090 PS00855 Signal peptidases II signature. 272560004091 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743 272560004092 catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818 272560004093 active site 272560004094 HIGH motif; other site 272560004095 KMSKS motif; other site 272560004096 Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960 272560004097 tRNA binding surface [nucleotide binding]; other site 272560004098 anticodon binding site; other site 272560004099 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 272560004100 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score 838.4, E-value 1.6e-249 272560004101 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560004102 bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627 272560004103 FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064 272560004104 active site 272560004105 Riboflavin kinase; Region: Flavokinase; smart00904 272560004106 Pfam match to entry PF01687 FAD_Synth, Riboflavin kinase / FAD synthetase , score 132.6, E-value 4.5e-37 272560004107 Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645 272560004108 active site 272560004109 substrate binding site [chemical binding]; other site 272560004110 cosubstrate binding site; other site 272560004111 catalytic site [active] 272560004112 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 256.7, E-value 2.1e-74 272560004113 16S rRNA methyltransferase B; Provisional; Region: PRK14901 272560004114 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560004115 S-adenosylmethionine binding site [chemical binding]; other site 272560004116 Pfam match to entry PF01189 Nol1_Nop2_Sun, NOL1/NOP2/sun family , score 204.9, E-value 8e-59 272560004117 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 272560004118 Mechanosensitive ion channel; Region: MS_channel; pfam00924 272560004119 6 probable transmembrane helices predicted for BPSL0910 by TMHMM2.0 at aa 20-39, 59-81, 91-113, 126-148, 173-195 and 221-243 272560004120 Pfam match to entry PF00924 MS_channel, Mechanosensitive ion channel , score 178.9, E-value 5.4e-51 272560004121 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560004122 The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505 272560004123 Di-iron ligands [ion binding]; other site 272560004124 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560004125 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 29.3, E-value 1e-07 272560004126 3 probable transmembrane helices predicted for BPSL0911 by TMHMM2.0 at aa 18-40, 142-164 and 169-188 272560004127 Signal peptide predicted for BPSL0912 by SignalP 2.0 HMM (Signal peptide probability 0.642) with cleavage site probability 0.641 between residues 27 and 28; signal peptide 272560004128 quinolinate synthetase; Provisional; Region: PRK09375 272560004129 Pfam match to entry PF02445 NadA, Quinolinate synthetase A protein , score 520.8, E-value 6.5e-154 272560004130 nicotinate-nucleotide pyrophosphorylase; Provisional; Region: PRK06978 272560004131 Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572 272560004132 dimerization interface [polypeptide binding]; other site 272560004133 active site 272560004134 Pfam match to entry PF02749 QRPTase_N, Quinolinate phosphoribosyl transferase, N-terminal domain , score 114.9, E-value 1e-31 272560004135 Pfam match to entry PF01729 QRPTase, Quinolinate phosphoribosyl transferase, C-terminal domain , score 253.0, E-value 2.7e-73 272560004136 L-aspartate oxidase; Provisional; Region: PRK09077 272560004137 L-aspartate oxidase; Provisional; Region: PRK06175 272560004138 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 272560004139 Pfam match to entry PF02910 succ_DH_flav_C, Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain , score 35.2, E-value 3.7e-11 272560004140 Pfam match to entry PF00890 FAD_binding_2, FAD binding domain , score 517.2, E-value 7.8e-153 272560004141 50S ribosomal protein L33; Validated; Region: rpmG; PRK00595 272560004142 Pfam match to entry PF00471 Ribosomal_L33, Ribosomal protein L33 , score 83.0, E-value 4e-22 272560004143 PS00582 Ribosomal protein L33 signature. 272560004144 50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359 272560004145 Pfam match to entry PF00830 Ribosomal_L28, Ribosomal L28 family , score 109.3, E-value 4.7e-30 272560004146 hypothetical protein; Reviewed; Region: PRK00024 272560004147 Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071 272560004148 MPN+ (JAMM) motif; other site 272560004149 Zinc-binding site [ion binding]; other site 272560004150 Pfam match to entry PF04002 RadC, RadC, DNA repair protein , score 209.4, E-value 3.4e-60 272560004151 PS01302 DNA repair protein radC family signature. 272560004152 FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047 272560004153 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl19519 272560004154 Pfam match to entry PF00254 FKBP, FKBP-type peptidyl-prolyl cis-trans isomerase , score 27.7, E-value 1.8e-05 272560004155 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944 272560004156 Fe-S cluster binding site [ion binding]; other site 272560004157 substrate binding site [chemical binding]; other site 272560004158 catalytic site [active] 272560004159 Pfam match to entry PF02401 LYTB, LytB protein , score 549.5, E-value 1.5e-162 272560004160 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560004161 TM-ABC transporter signature motif; other site 272560004162 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 190.0, E-value 2.4e-54 272560004163 7 probable transmembrane helices predicted for BPSL0920 by TMHMM2.0 at aa 13-35, 66-88, 101-123, 153-175, 203-225, 245-267 and 280-302 272560004164 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560004165 TM-ABC transporter signature motif; other site 272560004166 7 probable transmembrane helices predicted for BPSL0921 by TMHMM2.0 at aa 27-49, 56-75, 80-102, 115-137, 205-224, 255-277 and 292-314 272560004167 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 140.0, E-value 2.7e-39 272560004168 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560004169 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560004170 Walker A/P-loop; other site 272560004171 ATP binding site [chemical binding]; other site 272560004172 Q-loop/lid; other site 272560004173 ABC transporter signature motif; other site 272560004174 Walker B; other site 272560004175 D-loop; other site 272560004176 H-loop/switch region; other site 272560004177 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 191.7, E-value 7.3e-55 272560004178 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004179 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560004180 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560004181 Walker A/P-loop; other site 272560004182 ATP binding site [chemical binding]; other site 272560004183 Q-loop/lid; other site 272560004184 ABC transporter signature motif; other site 272560004185 Walker B; other site 272560004186 D-loop; other site 272560004187 H-loop/switch region; other site 272560004188 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 178.3, E-value 8e-51 272560004189 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004190 PS00211 ABC transporters family signature. 272560004191 Uncharacterized conserved protein (DUF2278); Region: DUF2278; pfam10042 272560004192 putative acetyltransferase; Provisional; Region: PRK03624 272560004193 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560004194 Coenzyme A binding pocket [chemical binding]; other site 272560004195 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 90.5, E-value 2.2e-24 272560004196 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560004197 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560004198 inhibitor-cofactor binding pocket; inhibition site 272560004199 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560004200 catalytic residue [active] 272560004201 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 417.2, E-value 9.9e-123 272560004202 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560004203 CDP-6-deoxy-delta-3,4-glucoseen reductase; Validated; Region: PRK07609 272560004204 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560004205 catalytic loop [active] 272560004206 iron binding site [ion binding]; other site 272560004207 NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189 272560004208 FAD binding pocket [chemical binding]; other site 272560004209 FAD binding motif [chemical binding]; other site 272560004210 phosphate binding motif [ion binding]; other site 272560004211 beta-alpha-beta structure motif; other site 272560004212 NAD binding pocket [chemical binding]; other site 272560004213 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 124.3, E-value 1.5e-34 272560004214 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 98.9, E-value 6.6e-27 272560004215 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 81.3, E-value 1.3e-21 272560004216 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560004217 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560004218 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560004219 NAD(P) binding site [chemical binding]; other site 272560004220 active site 272560004221 2 probable transmembrane helices predicted for BPSL0929 by TMHMM2.0 at aa 34-56 and 69-88 272560004222 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560004223 RNA binding surface [nucleotide binding]; other site 272560004224 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 272560004225 Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553 272560004226 active site 272560004227 uracil binding [chemical binding]; other site 272560004228 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 75.8, E-value 6e-20 272560004229 PS01149 Rsu family of pseudouridine synthase signature. 272560004230 Pfam match to entry PF01479 S4, S4 domain , score 21.4, E-value 0.0014 272560004231 Signal peptide predicted for BPSL0931 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.512 between residues 27 and 28; signal peptide 272560004232 CopC domain; Region: CopC; cl01012 272560004233 LysR family transcriptional regulator; Provisional; Region: PRK14997 272560004234 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004235 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560004236 dimerization interface [polypeptide binding]; other site 272560004237 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 158.5, E-value 7.6e-45 272560004238 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 74.1, E-value 1.9e-19 272560004239 PS00044 Bacterial regulatory proteins, lysR family signature. 272560004240 Predicted helix-turn-helix motif with score 1401.000, SD 3.96 at aa 20-41, sequence CGFSAAGRRLDMTPSAISKFVQ 272560004241 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560004242 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004243 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560004244 dimerization interface [polypeptide binding]; other site 272560004245 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 117.8, E-value 1.3e-32 272560004246 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 75.7, E-value 6.1e-20 272560004247 PS00044 Bacterial regulatory proteins, lysR family signature. 272560004248 Predicted helix-turn-helix motif with score 1310.000, SD 3.65 at aa 31-52, sequence RGFAPAAERLALTPSAVSGHIK 272560004249 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560004250 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 31.6, E-value 1.2e-06 272560004251 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258 272560004252 MOSC domain; Region: MOSC; pfam03473 272560004253 3-alpha domain; Region: 3-alpha; pfam03475 272560004254 Pfam match to entry PF03473 MOSC, MOSC domain , score 152.8, E-value 3.8e-43 272560004255 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 272560004256 inhibitor site; inhibition site 272560004257 active site 272560004258 dimer interface [polypeptide binding]; other site 272560004259 catalytic residue [active] 272560004260 Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase , score 181.3, E-value 1e-51 272560004261 class II aldolase/adducin domain protein; Provisional; Region: PRK07090 272560004262 intersubunit interface [polypeptide binding]; other site 272560004263 active site 272560004264 Zn2+ binding site [ion binding]; other site 272560004265 Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain , score 180.1, E-value 2.4e-51 272560004266 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004267 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560004268 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560004269 non-specific DNA binding site [nucleotide binding]; other site 272560004270 salt bridge; other site 272560004271 sequence-specific DNA binding site [nucleotide binding]; other site 272560004272 Cupin domain; Region: Cupin_2; pfam07883 272560004273 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 53.1, E-value 4e-13 272560004274 Predicted helix-turn-helix motif with score 1637.000, SD 4.76 at aa 7-28, sequence WTLDVLAEATGLTKSYLSKVER 272560004275 Low G+C region, possible genomic island region 272560004276 Predicted transcriptional regulator [Transcription]; Region: COG2378 272560004277 HTH domain; Region: HTH_11; pfam08279 272560004278 WYL domain; Region: WYL; pfam13280 272560004279 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family , score 20.7, E-value 6.9e-06 272560004280 Predicted helix-turn-helix motif with score 1213.000, SD 3.32 at aa 32-53, sequence VTIAELMVHLEVSRATLKRDFD 272560004281 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 272560004282 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 272560004283 HTH-like domain; Region: HTH_21; pfam13276 272560004284 Integrase core domain; Region: rve; pfam00665 272560004285 Integrase core domain; Region: rve_3; pfam13683 272560004286 Pfam match to entry PF00665 rve, Integrase core domain , score 138.4, E-value 8.6e-39 272560004287 Genomic island GI 5 272560004288 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560004289 active site 272560004290 DNA binding site [nucleotide binding] 272560004291 Int/Topo IB signature motif; other site 272560004292 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -36.5, E-value 0.092 272560004293 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610 272560004294 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313 272560004295 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560004296 ATP binding site [chemical binding]; other site 272560004297 putative Mg++ binding site [ion binding]; other site 272560004298 Protein of unknown function DUF91; Region: DUF91; cl00709 272560004299 Uncharacterized conserved protein [Function unknown]; Region: COG3586 272560004300 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 272560004301 Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732 272560004302 Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420 272560004303 Pfam match to entry PF01420 Methylase_S, Type I restriction modification DNA specificity domain , score 49.0, E-value 6.8e-12 272560004304 Pfam match to entry PF01420 Methylase_S, Type I restriction modification DNA specificity domain , score 28.2, E-value 3.9e-08 272560004305 Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286 272560004306 HsdM N-terminal domain; Region: HsdM_N; pfam12161 272560004307 Methyltransferase domain; Region: Methyltransf_26; pfam13659 272560004308 Pfam match to entry PF02384 N6_Mtase, N-6 DNA Methylase , score 40.2, E-value 1.2e-09 272560004309 PS00092 N-6 Adenine-specific DNA methylases signature. 272560004310 Pfam match to entry PF02506 Methylase_M, Type I restriction modification system, M protein , score -8.4, E-value 1.5e-10 272560004311 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 272560004312 DNA binding site [nucleotide binding] 272560004313 active site 272560004314 Int/Topo IB signature motif; other site 272560004315 catalytic residues [active] 272560004316 Transposase; Region: HTH_Tnp_1; pfam01527 272560004317 Pfam match to entry PF01527 Transposase_8, Transposase , score 134.4, E-value 1.3e-37 272560004318 Similar to the N-terminal regions of Ralstonia solanacearum ISRso14-transposase orfB protein SWALL:Q8XF72 (EMBL:AL646083) (275 aa) fasta scores: E(): 4.4e-14, 75.47% id in 53 aa, and Pseudomonas aeruginosa hypothetical protein PA0987 SWALL:Q9I4Y2 (EMBL:AE004531) (280 aa) fasta scores: E(): 6e-08, 54.9% id in 51 aa. Probable gene remnant;insertion element hypothetical protein (fragment) 272560004319 Replication initiator protein A; Region: RPA; cl19398 272560004320 Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523 272560004321 transcriptional regulator CysB-like protein; Reviewed; Region: PRK12684 272560004322 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004323 The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413 272560004324 substrate binding site [chemical binding]; other site 272560004325 dimerization interface [polypeptide binding]; other site 272560004326 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 159.0, E-value 5.2e-45 272560004327 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 60.8, E-value 1.9e-15 272560004328 PS00044 Bacterial regulatory proteins, lysR family signature. 272560004329 Predicted helix-turn-helix motif with score 1416.000, SD 4.01 at aa 17-38, sequence FNLTEAAKALYTSQPGVSKAII 272560004330 Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155 272560004331 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560004332 Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077 272560004333 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560004334 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560004335 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 62.8, E-value 4.7e-16 272560004336 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 53.8, E-value 2.5e-13 272560004337 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain , score 66.0, E-value 5.2e-17 272560004338 Bacterial protein of unknown function (DUF934); Region: DUF934; pfam06073 272560004339 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175 272560004340 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 272560004341 Active Sites [active] 272560004342 Pfam match to entry PF01507 PAPS_reduct, Phosphoadenosine phosphosulfate reductase , score 212.8, E-value 3.5e-61 272560004343 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175 272560004344 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 272560004345 Active Sites [active] 272560004346 Pfam match to entry PF01507 PAPS_reduct, Phosphoadenosine phosphosulfate reductase , score 167.4, E-value 1.5e-47 272560004347 GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895 272560004348 CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166 272560004349 CysD dimerization site [polypeptide binding]; other site 272560004350 G1 box; other site 272560004351 putative GEF interaction site [polypeptide binding]; other site 272560004352 GTP/Mg2+ binding site [chemical binding]; other site 272560004353 Switch I region; other site 272560004354 G2 box; other site 272560004355 G3 box; other site 272560004356 Switch II region; other site 272560004357 G4 box; other site 272560004358 G5 box; other site 272560004359 CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695 272560004360 TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095 272560004361 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 206.6, E-value 2.4e-59 272560004362 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004363 PS00301 GTP-binding elongation factors signature. 272560004364 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 30.9, E-value 1.9e-06 272560004365 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 272560004366 active site 272560004367 SAM binding site [chemical binding]; other site 272560004368 homodimer interface [polypeptide binding]; other site 272560004369 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 217.8, E-value 1e-62 272560004370 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 272560004371 PS00840 Uroporphyrin-III C-methyltransferase signature 2. 272560004372 Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416 272560004373 putative active site [active] 272560004374 Pfam match to entry PF01903 CbiX, CbiX , score 0.5, E-value 1e-05 272560004375 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 272560004376 6 probable transmembrane helices predicted for BPSL0963 by TMHMM2.0 at aa 12-34, 61-78, 99-121, 300-319, 326-348 and 358-380 272560004377 Pfam match to entry PF03739 YjgP_YjgQ, Predicted permease YjgP/YjgQ family , score 165.4, E-value 6.2e-47 272560004378 Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739 272560004379 Pfam match to entry PF03739 YjgP_YjgQ, Predicted permease YjgP/YjgQ family , score 161.4, E-value 9.8e-46 272560004380 6 probable transmembrane helices predicted for BPSL0964 by TMHMM2.0 at aa 13-35, 50-72, 102-124, 264-286, 295-314 and 324-346 272560004381 multifunctional aminopeptidase A; Provisional; Region: PRK00913 272560004382 Cytosol aminopeptidase family, N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases ( EC 3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433 272560004383 interface (dimer of trimers) [polypeptide binding]; other site 272560004384 Substrate-binding/catalytic site; other site 272560004385 Zn-binding sites [ion binding]; other site 272560004386 Pfam match to entry PF02789 Peptidase_M17_N, Cytosol aminopeptidase, N-terminal domain , score 81.2, E-value 1.4e-21 272560004387 Pfam match to entry PF00883 Peptidase_M17, Cytosol aminopeptidase, catalytic domain , score 630.7, E-value 5.4e-187 272560004388 PS00631 Cytosol aminopeptidase signature. 272560004389 DNA polymerase III subunit chi; Validated; Region: PRK05728 272560004390 Protein of unknown function (DUF2486); Region: DUF2486; pfam10667 272560004391 Cytochrome c; Region: Cytochrom_C; cl11414 272560004392 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 42.2, E-value 7.8e-10 272560004393 PS00190 Cytochrome c family heme-binding site signature. 272560004394 dihydroxy-acid dehydratase; Provisional; Region: PRK00911 272560004395 Pfam match to entry PF00920 ILVD_EDD, Dehydratase , score 964.9, E-value 1.3e-287 272560004396 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 272560004397 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 272560004398 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004399 The C-terminal substrate binding domain of LysR-type transcriptional regulator, IlvR, involved in the biosynthesis of isoleucine, leucine and valine; contains type 2 periplasmic binding fold; Region: PBP2_IlvR; cd08453 272560004400 putative dimerization interface [polypeptide binding]; other site 272560004401 putative substrate binding pocket [chemical binding]; other site 272560004402 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 111.0, E-value 1.5e-30 272560004403 Predicted helix-turn-helix motif with score 1485.000, SD 4.24 at aa 32-53, sequence RHFGRAAERLSMTQPPLSQAIR 272560004404 PS00044 Bacterial regulatory proteins, lysR family signature. 272560004405 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 159.1, E-value 4.8e-45 272560004406 prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052 272560004407 Pfam match to entry PF01790 LGT, Prolipoprotein diacylglyceryl transferase , score 355.6, E-value 3.5e-104 272560004408 5 probable transmembrane helices predicted for BPSL0971 by TMHMM2.0 at aa 17-39, 60-79, 94-116, 231-248 and 263-285 272560004409 PS01311 Prolipoprotein diacylglyceryl transferase signature. 272560004410 Signal peptide predicted for BPSL0972 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.816 between residues 30 and 31; signal peptide 272560004411 Protein of unknown function (DUF541); Region: SIMPL; cl01077 272560004412 EVE domain; Region: EVE; cl00728 272560004413 Cell division protein ZapA; Region: ZapA; pfam05164 272560004414 UV radiation resistance protein and autophagy-related subunit 14; Region: Atg14; pfam10186 272560004415 Signal peptide predicted for BPSL0976 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.211 between residues 22 and 23; signal peptide 272560004416 Outer membrane cobalamin receptor protein [Coenzyme metabolism]; Region: BtuB; COG4206 272560004417 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560004418 N-terminal plug; other site 272560004419 ligand-binding site [chemical binding]; other site 272560004420 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 46.8, E-value 3.2e-11 272560004421 Signal peptide predicted for BPSL0977 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.555 between residues 22 and 23; signal peptide 272560004422 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 272560004423 ABC-ATPase subunit interface; other site 272560004424 dimer interface [polypeptide binding]; other site 272560004425 putative PBP binding regions; other site 272560004426 9 probable transmembrane helices predicted for BPSL0977 by TMHMM2.0 at aa 7-29, 62-84, 91-110, 114-136, 152-174, 198-220, 241-263, 278-300 and 307-329 272560004427 Pfam match to entry PF01032 FecCD, FecCD transport family , score 237.6, E-value 1.2e-68 272560004428 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 272560004429 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 272560004430 Walker A/P-loop; other site 272560004431 ATP binding site [chemical binding]; other site 272560004432 Q-loop/lid; other site 272560004433 ABC transporter signature motif; other site 272560004434 Walker B; other site 272560004435 D-loop; other site 272560004436 H-loop/switch region; other site 272560004437 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 168.9, E-value 5.5e-48 272560004438 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004439 PS00211 ABC transporters family signature. 272560004440 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439 272560004441 putative dimer interface [polypeptide binding]; other site 272560004442 active site pocket [active] 272560004443 putative cataytic base [active] 272560004444 Pfam match to entry PF02277 DBI_PRT, Phosphoribosyltransferase , score 397.2, E-value 1e-116 272560004445 cobalamin synthase; Reviewed; Region: cobS; PRK00235 272560004446 Pfam match to entry PF02654 CobS, Cobalamin-5-phosphate synthase , score 58.3, E-value 1.1e-14 272560004447 5 probable transmembrane helices predicted for BPSL0980 by TMHMM2.0 at aa 36-58, 112-134, 139-161, 174-196 and 200-219 272560004448 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 272560004449 catalytic core [active] 272560004450 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score 3.1, E-value 9.5e-12 272560004451 2 probable transmembrane helices predicted for BPSL0982 by TMHMM2.0 at aa 205-227 and 237-256 272560004452 Signal peptide predicted for BPSL0983 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.339 between residues 25 and 26; signal peptide 272560004453 Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144 272560004454 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 272560004455 cobalamin binding residues [chemical binding]; other site 272560004456 putative BtuC binding residues; other site 272560004457 dimer interface [polypeptide binding]; other site 272560004458 Pfam match to entry PF01497 Peripla_BP_2, Periplasmic binding protein , score 107.4, E-value 1.8e-29 272560004459 putative threonine-phosphate decarboxylase; Provisional; Region: PRK06959 272560004460 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560004461 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560004462 catalytic residue [active] 272560004463 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 22.6, E-value 1.9e-06 272560004464 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560004465 cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209 272560004466 3 probable transmembrane helices predicted for BPSL0985 by TMHMM2.0 at aa 54-76, 154-176 and 288-310 272560004467 Pfam match to entry PF03186 CobD_Cbib, CobD/Cbib protein , score 282.2, E-value 4.2e-82 272560004468 Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544 272560004469 homotrimer interface [polypeptide binding]; other site 272560004470 Walker A motif; other site 272560004471 GTP binding site [chemical binding]; other site 272560004472 Walker B motif; other site 272560004473 Pfam match to entry PF02283 CobU, Cobinamide kinase / cobinamide phosphate guanyltransferase , score 215.9, E-value 3.9e-62 272560004474 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004475 Pfam match to entry PF01656 CbiA, Cobyrinic acid a,c-diamide synthase , score 333.4, E-value 1.7e-97 272560004476 cobyric acid synthase; Provisional; Region: PRK00784 272560004477 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560004478 Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750 272560004479 catalytic triad [active] 272560004480 Predicted membrane protein [Function unknown]; Region: COG2259 272560004481 4 probable transmembrane helices predicted for BPSL0988 by TMHMM2.0 at aa 7-29, 33-55, 62-79 and 94-116 272560004482 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 272560004483 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 272560004484 P-loop; other site 272560004485 Magnesium ion binding site [ion binding]; other site 272560004486 Pfam match to entry PF00991 ParA, ParA family ATPase , score 16.2, E-value 6e-05 272560004487 Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919 272560004488 tetramerization interface [polypeptide binding]; other site 272560004489 active site 272560004490 Pfam match to entry PF02261 Asp_decarbox, Aspartate decarboxylase , score 264.9, E-value 7.1e-77 272560004491 Pantoate-beta-alanine ligase; Region: PanC; cd00560 272560004492 active site 272560004493 ATP-binding site [chemical binding]; other site 272560004494 pantoate-binding site; other site 272560004495 HXXH motif; other site 272560004496 Pfam match to entry PF02569 Pantoate_ligase, Pantoate-beta-alanine ligase , score 376.5, E-value 1.8e-110 272560004497 Rec8/ScpA/Scc1-like protein (kleisin family) [Replication, recombination, and repair]; Region: scpA; COG1354 272560004498 Pfam match to entry PF02616 DUF173, Uncharacterized ACR, COG1354 , score 106.0, E-value 4.9e-29 272560004499 Protein of unknown function (DUF3460); Region: DUF3460; pfam11943 272560004500 Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729 272560004501 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560004502 Surface antigen; Region: Bac_surface_Ag; pfam01103 272560004503 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911 272560004504 Family of unknown function (DUF490); Region: DUF490; pfam04357 272560004505 1 probable transmembrane helix predicted for BPSL0995 by TMHMM2.0 at aa 38-60 272560004506 O-methyltransferase; Region: Methyltransf_2; pfam00891 272560004507 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560004508 S-adenosylmethionine binding site [chemical binding]; other site 272560004509 Pfam match to entry PF00891 Methyltransf_2, O-methyltransferase , score 66.9, E-value 2.8e-17 272560004510 methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133 272560004511 catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814 272560004512 active site 272560004513 HIGH motif; other site 272560004514 KMSKS motif; other site 272560004515 Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957 272560004516 tRNA binding surface [nucleotide binding]; other site 272560004517 anticodon binding site; other site 272560004518 tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins. This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties. MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800 272560004519 dimer interface [polypeptide binding]; other site 272560004520 putative tRNA-binding site [nucleotide binding]; other site 272560004521 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain , score 126.9, E-value 2.5e-35 272560004522 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score -210.7, E-value 6.9e-08 272560004523 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560004524 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 272560004525 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560004526 ligand binding site [chemical binding]; other site 272560004527 Pfam match to entry PF00691 OmpA, OmpA family , score 137.1, E-value 2.1e-38 272560004528 2 probable transmembrane helices predicted for BPSL0999 by TMHMM2.0 at aa 5-27 and 42-64 272560004529 Domain of unknown function DUF59; Region: DUF59; cl00941 272560004530 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149 272560004531 MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037 272560004532 Walker A motif; other site 272560004533 Pfam match to entry PF01883 DUF59, Domain of unknown function DUF59 , score -8.2, E-value 0.0026 272560004534 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004535 Pfam match to entry PF00991 ParA, ParA family ATPase , score 8.5, E-value 0.00031 272560004536 PS01215 Mrp family signature. 272560004537 Signal peptide predicted for BPSL1001 by SignalP 2.0 HMM (Signal peptide probabilty 0.934) with cleavage site probability 0.782 between residues 21 and 22; signal peptide 272560004538 Copper/zinc superoxide dismutase (SODC); Region: Sod_Cu; pfam00080 272560004539 E-class dimer interface [polypeptide binding]; other site 272560004540 P-class dimer interface [polypeptide binding]; other site 272560004541 active site 272560004542 Cu2+ binding site [ion binding]; other site 272560004543 Zn2+ binding site [ion binding]; other site 272560004544 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004545 Pfam match to entry PF00080 sodcu, Copper/zinc superoxide dismutase (SODC) , score 50.8, E-value 1e-12 272560004546 Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557 272560004547 trimer interface [polypeptide binding]; other site 272560004548 active site 272560004549 Pfam match to entry PF00692 dUTPase, dUTPase , score -9.7, E-value 0.0017 272560004550 Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709 272560004551 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982 272560004552 Orn/Lys/Arg decarboxylase, major domain; Region: OKR_DC_1; pfam01276 272560004553 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560004554 catalytic residue [active] 272560004555 Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711 272560004556 Pfam match to entry PF01276 OKR_DC_1, Orn/Lys/Arg decarboxylase, major domain , score 617.2, E-value 6e-183 272560004557 PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 272560004558 Pfam match to entry PF03711 OKR_DC_1_C, Orn/Lys/Arg decarboxylase, C-terminal domain , score 111.5, E-value 1.1e-30 272560004559 Signal peptide predicted for BPSL1004 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.987 between residues 30 and 31; signal peptide 272560004560 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 272560004561 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 272560004562 Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637 272560004563 haloacid dehalogenase-like hydrolase; Region: HAD; cl19137 272560004564 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560004565 motif II; other site 272560004566 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 108.1, E-value 1.1e-29 272560004567 argininosuccinate lyase; Provisional; Region: PRK00855 272560004568 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 272560004569 active sites [active] 272560004570 tetramer interface [polypeptide binding]; other site 272560004571 Pfam match to entry PF00206 lyase_1, Lyase , score 355.7, E-value 3.3e-104 272560004572 PS00163 Fumarate lyases signature. 272560004573 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560004574 Outer membrane usher protein; Region: Usher; pfam00577 272560004575 PapC C-terminal domain; Region: PapC_C; pfam13953 272560004576 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score -203.3, E-value 1.3e-11 272560004577 Signal peptide predicted for BPSL1008 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.863 between residues 23 and 24; signal peptide 272560004578 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 272560004579 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560004580 Signal peptide predicted for BPSL1009 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.959 between residues 41 and 42; signal peptide 272560004581 Uncharacterized secreted protein [Function unknown]; Region: COG5430 272560004582 Signal peptide predicted for BPSL1010 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 33 and 34; signal peptide 272560004583 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560004584 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560004585 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004586 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560004587 salt bridge; other site 272560004588 non-specific DNA binding site [nucleotide binding]; other site 272560004589 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560004590 sequence-specific DNA binding site [nucleotide binding]; other site 272560004591 Predicted helix-turn-helix motif with score 1733.000, SD 5.09 at aa 48-69, sequence LRREEVAQLCGVSPTWYTWIEQ 272560004592 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560004593 S-adenosylmethionine binding site [chemical binding]; other site 272560004594 Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase , score -82.4, E-value 4e-07 272560004595 phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009 272560004596 Pfam match to entry PF00311 PEPcase, Phosphoenolpyruvate carboxylase , score 300.0, E-value 1.9e-87 272560004597 PS00393 Phosphoenolpyruvate carboxylase active site 2. 272560004598 PS00781 Phosphoenolpyruvate carboxylase active site 1. 272560004599 porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072 272560004600 Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494 272560004601 domain interfaces; other site 272560004602 active site 272560004603 Pfam match to entry PF01379 Porphobil_deam, Porphobilinogen deaminase, dipyromethane cofactor binding domain , score 402.0, E-value 3.7e-118 272560004604 Pfam match to entry PF03900 Porphobil_deamC, Porphobilinogen deaminase, C-terminal domain , score 52.5, E-value 6e-13 272560004605 PS00533 Porphobilinogen deaminase cofactor-binding site. 272560004606 bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed; Region: PRK06975 272560004607 Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578 272560004608 active site 272560004609 HemX; Region: HemX; cl19375 272560004610 Pfam match to entry PF02602 HEM4, Uroporphyrinogen-III synthase HemD , score 41.8, E-value 9.8e-10 272560004611 1 probable transmembrane helix predicted for BPSL1016 by TMHMM2.0 at aa 328-350 272560004612 heme biosynthesis-associated TPR protein; Region: TPR_hemY_coli; TIGR00540 272560004613 HemY protein N-terminus; Region: HemY_N; pfam07219 272560004614 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560004615 TPR motif; other site 272560004616 binding surface 272560004617 2 probable transmembrane helices predicted for BPSL1017 by TMHMM2.0 at aa 5-27 and 42-64 272560004618 Pfam match to entry PF00515 TPR, TPR Domain , score 6.7, E-value 0.56 272560004619 Pfam match to entry PF00515 TPR, TPR Domain , score 12.3, E-value 0.14 272560004620 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 272560004621 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560004622 putative substrate translocation pore; other site 272560004623 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -54.9, E-value 6.8e-06 272560004624 12 probable transmembrane helices predicted for BPSL1018 by TMHMM2.0 at aa 24-41, 63-85, 98-120, 124-146, 153-175, 190-209, 253-275, 285-307, 320-337, 341-363, 370-392 and 407-429 272560004625 PS00778 Histidine acid phosphatases active site signature. 272560004626 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560004627 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 272560004628 NAD(P) binding site [chemical binding]; other site 272560004629 active site 272560004630 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 242.3, E-value 4.3e-70 272560004631 Uncharacterized Saccharopolyspora spinosa aldehyde dehydrogenase (AAS00426)-like; Region: ALDH_AAS00426; cd07109 272560004632 NAD(P) binding site [chemical binding]; other site 272560004633 catalytic residues [active] 272560004634 catalytic residues [active] 272560004635 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 555.4, E-value 2.5e-164 272560004636 PS00070 Aldehyde dehydrogenases cysteine active site. 272560004637 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560004638 Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412 272560004639 dimer interface [polypeptide binding]; other site 272560004640 substrate binding site [chemical binding]; other site 272560004641 metal binding sites [ion binding]; metal-binding site 272560004642 Pfam match to entry PF00719 Pyrophosphatase, Inorganic pyrophosphatase , score 209.7, E-value 2.9e-60 272560004643 PS00387 Inorganic pyrophosphatase signature. 272560004644 The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456 272560004645 GIY-YIG motif/motif A; other site 272560004646 putative active site [active] 272560004647 putative metal binding site [ion binding]; other site 272560004648 Similar to parts of Caulobacter crescentus beta-D-glucosidase cc0968 SWALL:Q9A9L2 (EMBL:AE005774) (758 aa) fasta scores: E(): 2.3e-19, 42.42% id in 165 aa, and of Agrobacterium tumefaciens beta-glucosidase Cbg-1 SWALL:BGLS_AGRTU (SWALL:P27034) (818 aa) fasta scores: E(): 9.6e-12, 36.58% id in 164 aa; beta-glucosidase (fragment) 272560004649 Pfam match to entry PF01915 Glyco_hydro_3_C, Glycosyl hydrolase 3 C terminal domain , score 43.9, E-value 1.9e-12 272560004650 Protein of unknown function, DUF482; Region: DUF482; pfam04339 272560004651 NAD synthetase; Provisional; Region: PRK13981 272560004652 Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570 272560004653 multimer interface [polypeptide binding]; other site 272560004654 active site 272560004655 catalytic triad [active] 272560004656 protein interface 1 [polypeptide binding]; other site 272560004657 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 272560004658 homodimer interface [polypeptide binding]; other site 272560004659 NAD binding pocket [chemical binding]; other site 272560004660 ATP binding pocket [chemical binding]; other site 272560004661 Mg binding site [ion binding]; other site 272560004662 active-site loop [active] 272560004663 Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase , score 12.9, E-value 2.2e-10 272560004664 Pfam match to entry PF02540 NAD_synthase, NAD synthase , score 248.4, E-value 6.4e-72 272560004665 Nitrogen regulatory protein P-II; Region: P-II; pfam00543 272560004666 Pfam match to entry PF00543 P-II, Nitrogen regulatory protein P-II , score 218.1, E-value 8.5e-63 272560004667 PS00496 P-II protein urydylation site. 272560004668 PS00638 P-II protein C-terminal region signature. 272560004669 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560004670 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560004671 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560004672 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560004673 Pfam match to entry PF01610 Transposase_12, Transposase , score 376.8, E-value 1.4e-110 272560004674 Signal peptide predicted for BPSL1029 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.978 between residues 23 and 24; signal peptide 272560004675 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560004676 trimer interface [polypeptide binding]; other site 272560004677 eyelet of channel; other site 272560004678 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -110.4, E-value 0.069 272560004679 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 272560004680 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560004681 Walker A/P-loop; other site 272560004682 ATP binding site [chemical binding]; other site 272560004683 Q-loop/lid; other site 272560004684 ABC transporter signature motif; other site 272560004685 Walker B; other site 272560004686 D-loop; other site 272560004687 H-loop/switch region; other site 272560004688 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 214.8, E-value 8.2e-62 272560004689 PS00211 ABC transporters family signature. 272560004690 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004691 ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160 272560004692 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560004693 dimer interface [polypeptide binding]; other site 272560004694 conserved gate region; other site 272560004695 putative PBP binding loops; other site 272560004696 ABC-ATPase subunit interface; other site 272560004697 4 probable transmembrane helices predicted for BPSL1031 by TMHMM2.0 at aa 20-42, 57-79, 167-189 and 199-221 272560004698 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 32.1, E-value 8.6e-07 272560004699 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560004700 Predicted helix-turn-helix motif with score 1241.000, SD 3.41 at aa 130-151, sequence YGEIEAARAYGMSTFTLYRRIV 272560004701 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 272560004702 Signal peptide predicted for BPSL1032 by SignalP 2.0 HMM (Signal peptide probabilty 0.794) with cleavage site probability 0.327 between residues 37 and 38; signal peptide 272560004703 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560004704 dimer interface [polypeptide binding]; other site 272560004705 conserved gate region; other site 272560004706 putative PBP binding loops; other site 272560004707 ABC-ATPase subunit interface; other site 272560004708 5 probable transmembrane helices predicted for BPSL1032 by TMHMM2.0 at aa 15-37, 49-71, 91-109, 150-172 and 192-214 272560004709 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 62.2, E-value 7.2e-16 272560004710 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560004711 Signal peptide predicted for BPSL1033 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 19 and 20; signal peptide 272560004712 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 272560004713 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560004714 substrate binding pocket [chemical binding]; other site 272560004715 membrane-bound complex binding site; other site 272560004716 hinge residues; other site 272560004717 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 291.7, E-value 6e-85 272560004718 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560004719 Pirin-related protein [General function prediction only]; Region: COG1741 272560004720 Pirin; Region: Pirin; pfam02678 272560004721 Pfam match to entry PF02678 DUF209, Uncharacterized BCR, YhhW family COG1741 , score 381.1, E-value 7.4e-112 272560004722 CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cl01482 272560004723 Predicted helix-turn-helix motif with score 1012.000, SD 2.63 at aa 99-120, sequence MMMQRIHDKLNLSAAQEQQWQA 272560004724 osmolarity response regulator; Provisional; Region: ompR; PRK09468 272560004725 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560004726 active site 272560004727 phosphorylation site [posttranslational modification] 272560004728 intermolecular recognition site; other site 272560004729 dimerization interface [polypeptide binding]; other site 272560004730 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560004731 DNA binding site [nucleotide binding] 272560004732 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 154.8, E-value 9.7e-44 272560004733 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 87.8, E-value 1.5e-23 272560004734 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560004735 dimerization interface [polypeptide binding]; other site 272560004736 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920 272560004737 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560004738 dimer interface [polypeptide binding]; other site 272560004739 phosphorylation site [posttranslational modification] 272560004740 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560004741 ATP binding site [chemical binding]; other site 272560004742 Mg2+ binding site [ion binding]; other site 272560004743 G-X-G motif; other site 272560004744 2 probable transmembrane helices predicted for BPSL1037 by TMHMM2.0 at aa 10-31 and 146-168 272560004745 Pfam match to entry PF00672 HAMP, HAMP domain , score 55.0, E-value 1.1e-13 272560004746 Predicted helix-turn-helix motif with score 1006.000, SD 2.61 at aa 197-218, sequence RELRQLTHGFNQMVQQVSRAEN 272560004747 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 56.1, E-value 5e-14 272560004748 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 92.1, E-value 7.4e-25 272560004749 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 272560004750 ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986 272560004751 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560004752 dimer interface [polypeptide binding]; other site 272560004753 conserved gate region; other site 272560004754 putative PBP binding loops; other site 272560004755 ABC-ATPase subunit interface; other site 272560004756 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560004757 dimer interface [polypeptide binding]; other site 272560004758 conserved gate region; other site 272560004759 putative PBP binding loops; other site 272560004760 ABC-ATPase subunit interface; other site 272560004761 13 probable transmembrane helices predicted for BPSL1039 by TMHMM2.0 at aa 26-43, 73-95, 110-132, 137-159, 190-212, 219-238, 242-264, 343-365, 385-407, 419-441, 451-473, 494-516 and 552-571 272560004762 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 36.6, E-value 3.6e-08 272560004763 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 22.5, E-value 0.00037 272560004764 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 272560004765 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 272560004766 Walker A/P-loop; other site 272560004767 ATP binding site [chemical binding]; other site 272560004768 Q-loop/lid; other site 272560004769 ABC transporter signature motif; other site 272560004770 Walker B; other site 272560004771 D-loop; other site 272560004772 H-loop/switch region; other site 272560004773 C-terminal AAA-associated domain; Region: AAA_assoc_C; pfam09821 272560004774 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 204.3, E-value 1.2e-58 272560004775 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004776 PS00211 ABC transporters family signature. 272560004777 Signal peptide predicted for BPSL1042 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.561 between residues 43 and 44; signal peptide 272560004778 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004779 Signal peptide predicted for BPSL1043 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.343 between residues 37 and 38; signal peptide 272560004780 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004781 alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400 272560004782 Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788 272560004783 active site 272560004784 homotetramer interface [polypeptide binding]; other site 272560004785 Pfam match to entry PF00982 Glyco_transf_20, Glycosyltransferase 20 , score 603.6, E-value 7.7e-179 272560004786 AAA domain; Region: AAA_28; pfam13521 272560004787 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004788 Glycine zipper; Region: Gly-zipper_Omp; pfam13488 272560004789 2 probable transmembrane helices predicted for BPSL1046 by TMHMM2.0 at aa 144-163 and 167-186 272560004790 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560004791 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560004792 putative substrate translocation pore; other site 272560004793 14 probable transmembrane helices predicted for BPSL1048 by TMHMM2.0 at aa 31-53, 68-90, 99-121, 126-145, 158-180, 185-207, 219-236, 246-263, 283-305, 320-342, 349-371, 377-394, 415-437 and 442-464 272560004794 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 15.8, E-value 5.3e-05 272560004795 PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865 272560004796 substrate binding site [chemical binding]; other site 272560004797 Possible gene remnant. Similar to N-terminal region of Agrobacterium tumefaciens hypothetical protein atu1777 or agr_c_3266 SWALL:Q8UEI0 (EMBL:AE009133) (114 aa) fasta scores: E(): 2.8, 33.82% id in 68 aa; membrane protein (fragment) 272560004798 2 probable transmembrane helices predicted for BPSL1051 by TMHMM2.0 at aa 5-22 and 26-48 272560004799 Signal peptide predicted for BPSL1053 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.933 between residues 19 and 20; signal peptide 272560004800 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560004801 Signal peptide predicted for BPSL1054 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.568 between residues 25 and 26; signal peptide 272560004802 ecotin; Provisional; Region: PRK03719 272560004803 secondary substrate binding site; other site 272560004804 primary substrate binding site; other site 272560004805 inhibition loop; other site 272560004806 dimerization interface [polypeptide binding]; other site 272560004807 Pfam match to entry PF03974 Ecotin, Ecotin , score 189.2, E-value 4.2e-54 272560004808 Signal peptide predicted for BPSL1055 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 38 and 39; signal peptide 272560004809 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191 272560004810 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 272560004811 PS00294 Prenyl group binding site (CAAX box). 272560004812 Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase , score 191.6, E-value 8.1e-55 272560004813 Partial CDS. Similar to the N-terminal region of Xanthomonas axonopodis hypothetical protein xac3889 SWALL:Q8PFT4 (EMBL:AE012038) (141 aa) fasta scores: E(): 2.8, 36.5% id in 63 aa; membrane protein (fragment) 272560004814 2 probable transmembrane helices predicted for BPSL1056 by TMHMM2.0 at aa 19-41 and 51-73 272560004815 Signal peptide predicted for BPSL1057 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 between residues 28 and 29; signal peptide 272560004816 Inhibitor of vertebrate lysozyme (Ivy); Region: Ivy; pfam08816 272560004817 Gene remnant. Similar to the C-terminal regions of Bradyrhizobium japonicum ID49 rsbeta5 SWALL:Q9ANP4 (EMBL:AF322012) (275 aa) fasta scores: E(): 3.4e-22, 58% id in 100 aa, and to Rhizobium meliloti transposase r03101 or smc03248 SWALL:Q92LG0 (EMBL:AL591792) (276 aa) fasta scores: E(): 2.4e-20, 55.44% id in 101 aa; transposase (fragment) 272560004818 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 272560004819 rRNA binding site [nucleotide binding]; other site 272560004820 predicted 30S ribosome binding site; other site 272560004821 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 30.4, E-value 2.8e-06 272560004822 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560004823 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560004824 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 43.0, E-value 4.5e-10 272560004825 Predicted membrane protein (DUF2306); Region: DUF2306; cl02232 272560004826 12 probable transmembrane helices predicted for BPSL1065 by TMHMM2.0 at aa 29-51, 126-148, 161-183, 193-215, 228-250, 260-282, 312-331, 364-386, 399-421, 431-450, 463-484 and 499-521 272560004827 Rubredoxin [Energy production and conversion]; Region: COG1773 272560004828 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 272560004829 iron binding site [ion binding]; other site 272560004830 Pfam match to entry PF00301 rubredoxin, Rubredoxin , score 98.8, E-value 6.9e-27 272560004831 PS00202 Rubredoxin signature. 272560004832 Domain of unknown function (DUF4399); Region: DUF4399; pfam14347 272560004833 ABC transporter ATPase component; Reviewed; Region: PRK11147 272560004834 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560004835 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560004836 Walker A/P-loop; other site 272560004837 ATP binding site [chemical binding]; other site 272560004838 Q-loop/lid; other site 272560004839 ABC transporter signature motif; other site 272560004840 Walker B; other site 272560004841 D-loop; other site 272560004842 ABC transporter; Region: ABC_tran_2; pfam12848 272560004843 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560004844 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 174.7, E-value 1e-49 272560004845 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004846 PS00211 ABC transporters family signature. 272560004847 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 150.8, E-value 1.5e-42 272560004848 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004849 PS00211 ABC transporters family signature. 272560004850 DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559 272560004851 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560004852 ATP binding site [chemical binding]; other site 272560004853 Mg2+ binding site [ion binding]; other site 272560004854 G-X-G motif; other site 272560004855 TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822 272560004856 anchoring element; other site 272560004857 dimer interface [polypeptide binding]; other site 272560004858 ATP binding site [chemical binding]; other site 272560004859 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 272560004860 active site 272560004861 metal binding site [ion binding]; metal-binding site 272560004862 DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986 272560004863 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 86.2, E-value 4.3e-23 272560004864 Pfam match to entry PF00204 DNA_gyraseB, DNA gyrase B , score 104.0, E-value 1.9e-28 272560004865 PS00177 DNA topoisomerase II signature. 272560004866 Pfam match to entry PF00986 DNA_gyraseB_C, DNA gyrase B subunit, carboxyl terminus , score 74.6, E-value 1.4e-19 272560004867 DNA topoisomerase IV subunit A; Validated; Region: PRK05561 272560004868 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 272560004869 CAP-like domain; other site 272560004870 active site 272560004871 primary dimer interface [polypeptide binding]; other site 272560004872 Pfam match to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A , score 778.6, E-value 1.6e-231 272560004873 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 10.9, E-value 0.077 272560004874 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 20.8, E-value 0.0022 272560004875 Predicted integral membrane protein [Function unknown]; Region: COG5615 272560004876 4 probable transmembrane helices predicted for BPSL1071 by TMHMM2.0 at aa 5-22, 43-65, 76-98 and 119-141 272560004877 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004878 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560004879 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560004880 dimerization interface [polypeptide binding]; other site 272560004881 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 83.6, E-value 2.7e-22 272560004882 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 66.8, E-value 3e-17 272560004883 Predicted helix-turn-helix motif with score 1527.000, SD 4.39 at aa 18-39, sequence GSFSAAARKLGKRQSTVSEAIA 272560004884 Predicted membrane protein [Function unknown]; Region: COG4125 272560004885 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 272560004886 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 272560004887 4 probable transmembrane helices predicted for BPSL1073 by TMHMM2.0 at aa 21-43, 47-69, 90-112 and 119-141 272560004888 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560004889 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560004890 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560004891 dimerization interface [polypeptide binding]; other site 272560004892 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 104.0, E-value 1.9e-28 272560004893 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 84.3, E-value 1.6e-22 272560004894 PS00044 Bacterial regulatory proteins, lysR family signature. 272560004895 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 39-60, sequence RSVSRAAARLHVTQPAVSQALK 272560004896 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560004897 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560004898 putative substrate translocation pore; other site 272560004899 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 42.7, E-value 5.6e-10 272560004900 10 probable transmembrane helices predicted for BPSL1075 by TMHMM2.0 at aa 7-25, 35-57, 78-100, 128-150, 163-185, 213-235, 247-269, 311-333, 346-368 and 373-395 272560004901 allantoate amidohydrolase; Reviewed; Region: PRK12893 272560004902 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 272560004903 active site 272560004904 metal binding site [ion binding]; metal-binding site 272560004905 dimer interface [polypeptide binding]; other site 272560004906 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 65.4, E-value 7.8e-17 272560004907 Histone deacetylase class IIa; Region: HDAC_classII_APAH; cd10001 272560004908 active site 272560004909 Zn binding site [ion binding]; other site 272560004910 Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase , score 180.7, E-value 1.5e-51 272560004911 Chromate transporter; Region: Chromate_transp; pfam02417 272560004912 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 272560004913 Chromate transporter; Region: Chromate_transp; pfam02417 272560004914 10 probable transmembrane helices predicted for BPSL1079 by TMHMM2.0 at aa 12-34, 84-106, 113-135, 150-181, 202-221, 231-253, 265-287, 291-313, 333-350 and 374-396 272560004915 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 0.4, E-value 1.5e-05 272560004916 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 16.1, E-value 1.9e-06 272560004917 Signal peptide predicted for BPSL1080 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.343 between residues 39 and 40; signal peptide 272560004918 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560004919 metal binding site [ion binding]; metal-binding site 272560004920 active site 272560004921 I-site; other site 272560004922 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560004923 Pfam match to entry PF00563 EAL, EAL domain , score 380.8, E-value 9.2e-112 272560004924 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 169.3, E-value 4.1e-48 272560004925 2 probable transmembrane helices predicted for BPSL1080 by TMHMM2.0 at aa 27-49 and 300-322 272560004926 Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384 272560004927 Diaminopimelate epimerase; Region: DAP_epimerase; cl19724 272560004928 Pfam match to entry PF02567 PhzC-PhzF, Phenazine biosynthesis-like protein , score 210.7, E-value 1.5e-60 272560004929 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_1; cd02199 272560004930 homotrimer interaction site [polypeptide binding]; other site 272560004931 putative active site [active] 272560004932 Pfam match to entry PF01042 UPF0076, YjgF family , score 69.5, E-value 4.5e-18 272560004933 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436 272560004934 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560004935 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560004936 homodimer interface [polypeptide binding]; other site 272560004937 catalytic residue [active] 272560004938 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 8.6, E-value 4.2e-07 272560004939 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560004940 EamA-like transporter family; Region: EamA; pfam00892 272560004941 EamA-like transporter family; Region: EamA; pfam00892 272560004942 10 probable transmembrane helices predicted for BPSL1084 by TMHMM2.0 at aa 7-29, 39-56, 69-89, 94-116, 123-140, 145-167, 180-202, 217-239, 246-265 and 270-292 272560004943 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 45.0, E-value 1.1e-10 272560004944 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 50.5, E-value 2.4e-12 272560004945 Glyoxalase-like domain; Region: Glyoxalase_3; pfam13468 272560004946 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560004947 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560004948 DNA-binding site [nucleotide binding]; DNA binding site 272560004949 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560004950 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560004951 homodimer interface [polypeptide binding]; other site 272560004952 catalytic residue [active] 272560004953 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 53.0, E-value 4.2e-13 272560004954 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 30.8, E-value 9.8e-09 272560004955 heat shock protein 90; Provisional; Region: PRK05218 272560004956 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560004957 ATP binding site [chemical binding]; other site 272560004958 Mg2+ binding site [ion binding]; other site 272560004959 G-X-G motif; other site 272560004960 Hsp90 protein; Region: HSP90; pfam00183 272560004961 PS00298 Heat shock hsp90 proteins family signature. 272560004962 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 44.2, E-value 2e-10 272560004963 Pfam match to entry PF00183 HSP90, Hsp90 protein , score 626.4, E-value 1.1e-185 272560004964 Chorismate lyase; Region: Chor_lyase; cl01230 272560004965 MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032 272560004966 putative active site [active] 272560004967 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560004968 Protein of unknown function (DUF3311); Region: DUF3311; pfam11755 272560004969 2 probable transmembrane helices predicted for BPSL1092 by TMHMM2.0 at aa 13-31 and 41-63 272560004970 Na+/proline symporter [Amino acid transport and metabolism / General function prediction only]; Region: PutP; COG0591 272560004971 Na binding site [ion binding]; other site 272560004972 13 probable transmembrane helices predicted for BPSL1093 by TMHMM2.0 at aa 4-26, 47-69, 79-101, 122-144, 159-181, 194-216, 236-258, 279-301, 337-359, 380-402, 406-428, 435-454 and 474-496 272560004973 Pfam match to entry PF00474 SSF, Sodium:solute symporter family , score -100.5, E-value 1.8e-05 272560004974 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 272560004975 dimer interface [polypeptide binding]; other site 272560004976 transaldolase-like protein; Provisional; Region: PTZ00411 272560004977 Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957 272560004978 active site 272560004979 dimer interface [polypeptide binding]; other site 272560004980 catalytic residue [active] 272560004981 Pfam match to entry PF00923 Transaldolase, Transaldolase , score 480.9, E-value 6.8e-142 272560004982 PS00958 Transaldolase active site. 272560004983 PS01054 Transaldolase signature 1. 272560004984 Benzoate membrane transport protein; Region: BenE; pfam03594 272560004985 Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135 272560004986 Pfam match to entry PF03594 BenE, Benzoate membrane transport protein , score 735.9, E-value 1.1e-218 272560004987 12 probable transmembrane helices predicted for BPSL1096 by TMHMM2.0 at aa 26-48, 63-80, 87-106, 111-130, 137-155, 160-178, 185-207, 217-239, 269-291, 306-328, 335-357 and 372-394 272560004988 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3825 272560004989 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 272560004990 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560004991 Walker A motif; other site 272560004992 ATP binding site [chemical binding]; other site 272560004993 Walker B motif; other site 272560004994 arginine finger; other site 272560004995 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 31.8, E-value 2.4e-07 272560004996 PS00017 ATP/GTP-binding site motif A (P-loop). 272560004997 Signal peptide predicted for BPSL1099 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.976 between residues 23 and 24; signal peptide 272560004998 Cytochrome c553 [Energy production and conversion]; Region: COG2863 272560004999 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 30.3, E-value 3e-06 272560005000 PS00190 Cytochrome c family heme-binding site signature. 272560005001 Signal peptide predicted for BPSL1100 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 27 and 28; signal peptide 272560005002 Cytochrome c; Region: Cytochrom_C; cl11414 272560005003 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 26.6, E-value 3.8e-05 272560005004 PS00190 Cytochrome c family heme-binding site signature. 272560005005 Domain of unknown function (DUF1841); Region: DUF1841; pfam08897 272560005006 Signal peptide predicted for BPSL1102 by SignalP 2.0 HMM (Signal peptide probabilty 0.956) with cleavage site probability 0.857 between residues 37 and 38; signal peptide 272560005007 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560005008 EamA-like transporter family; Region: EamA; pfam00892 272560005009 EamA-like transporter family; Region: EamA; pfam00892 272560005010 10 probable transmembrane helices predicted for BPSL1102 by TMHMM2.0 at aa 13-32, 42-61, 74-96, 101-123, 130-149, 154-173, 186-208, 218-240, 253-270 and 274-293 272560005011 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 72.5, E-value 5.8e-19 272560005012 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 85.7, E-value 6.3e-23 272560005013 Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177 272560005014 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 272560005015 minor groove reading motif; other site 272560005016 helix-hairpin-helix signature motif; other site 272560005017 substrate binding pocket [chemical binding]; other site 272560005018 active site 272560005019 iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525 272560005020 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein , score 254.0, E-value 1.4e-73 272560005021 PS01155 Endonuclease III family signature. 272560005022 ferredoxin; Provisional; Region: PRK06991 272560005023 Putative Fe-S cluster; Region: FeS; cl17515 272560005024 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560005025 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 22.7, E-value 4.9e-05 272560005026 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560005027 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 37.4, E-value 2.1e-08 272560005028 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560005029 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560005030 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560005031 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 61.0, E-value 1.7e-15 272560005032 Poly-beta-hydroxyalkanoate depolymerase [Lipid metabolism]; Region: DepA; COG4553 272560005033 Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387 272560005034 Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723 272560005035 Signal peptide predicted for BPSL1108 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 37 and 38; signal peptide 272560005036 Lactonase, 7-bladed beta-propeller; Region: Lactonase; pfam10282 272560005037 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 272560005038 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 272560005039 AAA-like domain; Region: AAA_10; pfam12846 272560005040 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 272560005041 Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family , score 315.3, E-value 4.8e-92 272560005042 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005043 3 probable transmembrane helices predicted for BPSL1109 by TMHMM2.0 at aa 5-24, 39-61 and 81-103 272560005044 sortase-like anchoring sequence 272560005045 signal peptide sequence 272560005046 META domain; Region: META; pfam03724 272560005047 Pfam match to entry PF03724 DUF306, Domain of unknown function (306) , score 27.8, E-value 2.3e-06 272560005048 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005049 phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288 272560005050 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560005051 ATP-grasp domain; Region: ATP-grasp; pfam02222 272560005052 Pfam match to entry PF02222 ATP-grasp, ATP-grasp domain , score 158.7, E-value 6.4e-45 272560005053 Signal peptide predicted for BPSL1112 by SignalP 2.0 HMM (Signal peptide probabilty 0.711) with cleavage site probability 0.426 between residues 47 and 48; signal peptide 272560005054 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005055 Signal peptide predicted for BPSL1113 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 23 and 24; signal peptide 272560005056 Membrane-bound lysozyme-inhibitor of c-type lysozyme; Region: MliC; pfam09864 272560005057 PS00099 Thiolases active site. 272560005058 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560005059 ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837 272560005060 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 272560005061 ATP binding site [chemical binding]; other site 272560005062 Mg++ binding site [ion binding]; other site 272560005063 motif III; other site 272560005064 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560005065 nucleotide binding region [chemical binding]; other site 272560005066 ATP-binding site [chemical binding]; other site 272560005067 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 298.2, E-value 6.6e-87 272560005068 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005069 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 272560005070 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 123.3, E-value 3e-34 272560005071 glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710 272560005072 active site 272560005073 nucleotide binding site [chemical binding]; other site 272560005074 HIGH motif; other site 272560005075 KMSKS motif; other site 272560005076 Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q), catalytic domain , score 17.5, E-value 2e-16 272560005077 rhodanese superfamily protein; Provisional; Region: PRK05320 272560005078 Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518 272560005079 active site residue [active] 272560005080 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 30.2, E-value 3.2e-06 272560005081 DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673 272560005082 Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433 272560005083 putative active site [active] 272560005084 putative PHP Thumb interface [polypeptide binding]; other site 272560005085 Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733 272560005086 Helix-hairpin-helix motif; Region: HHH_6; pfam14579 272560005087 DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485 272560005088 generic binding surface II; other site 272560005089 generic binding surface I; other site 272560005090 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region , score 84.2, E-value 1.8e-22 272560005091 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region , score 63.7, E-value 2.6e-16 272560005092 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain , score 48.4, E-value 1e-11 272560005093 lipid A export permease/ATP-binding protein MsbA; Region: MsbA_lipidA; TIGR02203 272560005094 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560005095 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560005096 Walker A/P-loop; other site 272560005097 ATP binding site [chemical binding]; other site 272560005098 Q-loop/lid; other site 272560005099 ABC transporter signature motif; other site 272560005100 Walker B; other site 272560005101 D-loop; other site 272560005102 H-loop/switch region; other site 272560005103 6 probable transmembrane helices predicted for BPSL1118 by TMHMM2.0 at aa 34-56, 76-98, 135-157, 172-194, 259-281 and 291-313 272560005104 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 154.8, E-value 9.9e-44 272560005105 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 215.2, E-value 6.5e-62 272560005106 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005107 PS00211 ABC transporters family signature. 272560005108 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560005109 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560005110 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 35.9, E-value 6.2e-08 272560005111 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560005112 putative active site [active] 272560005113 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 39.4, E-value 4.7e-09 272560005114 Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307 272560005115 O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425 272560005116 10 probable transmembrane helices predicted for BPSL1121 by TMHMM2.0 at aa 11-28, 32-51, 58-77, 92-109, 116-138, 153-171, 178-200, 215-237, 345-367 and 396-415 272560005117 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560005118 This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811 272560005119 putative ADP-binding pocket [chemical binding]; other site 272560005120 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 137.5, E-value 1.6e-38 272560005121 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560005122 putative active site [active] 272560005123 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 41.4, E-value 1.3e-09 272560005124 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 272560005125 UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511 272560005126 putative metal binding site; other site 272560005127 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 61.8, E-value 9.9e-16 272560005128 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560005129 Domain of unknown function (DUF3315); Region: DUF3315; cl02275 272560005130 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 272560005131 3 probable transmembrane helices predicted for BPSL1126 by TMHMM2.0 at aa 98-120, 133-155 and 165-187 272560005132 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560005133 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560005134 putative substrate translocation pore; other site 272560005135 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -57.8, E-value 8.6e-06 272560005136 12 probable transmembrane helices predicted for BPSL1127 by TMHMM2.0 at aa 20-37, 47-69, 81-103, 107-129, 142-164, 168-185, 226-248, 258-280, 292-314, 324-343, 350-372 and 377-399 272560005137 Signal peptide predicted for BPSL1128 by SignalP 2.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.384 between residues 43 and 44; signal peptide 272560005138 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005139 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 272560005140 Uncharacterized conserved protein [Function unknown]; Region: COG2128 272560005141 RNA polymerase sigma-70 factor, TIGR02957 family; Region: SigX4 272560005142 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560005143 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 272560005144 DNA binding residues [nucleotide binding] 272560005145 Predicted helix-turn-helix motif with score 1153.000, SD 3.11 at aa 150-171, sequence RDYAEIAQLLDKSEAACRQLVH 272560005146 Pseudogene. Similar to Yersinia pestis hypothetical protein ypo0904 SWALL:Q8ZHI9 (EMBL:AJ414145) (145 aa) fasta scores: E(): 2.4e-11, 34.78% id in 138 aa;conserved hypothetical protein (pseudogene) 272560005147 phospholipase C accessory protein PlcR; Region: plc_access_R; TIGR03398 272560005148 Pectinacetylesterase; Region: PAE; pfam03283 272560005149 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560005150 xanthine permease; Region: pbuX; TIGR03173 272560005151 12 probable transmembrane helices predicted for BPSL1136 by TMHMM2.0 at aa 44-64, 69-86, 91-113, 128-150, 157-179, 194-213, 218-240, 260-282, 353-375, 379-401, 408-425 and 435-457 272560005152 Pfam match to entry PF00860 xan_ur_permease, Permease , score 428.9, E-value 3e-126 272560005153 PS01116 Xanthine/uracil permeases family signature. 272560005154 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 272560005155 Genomic island GI 6; integrated phage 272560005156 VirC1 protein; Region: VirC1; cl17401 272560005157 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 272560005158 CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656 272560005159 P-loop; other site 272560005160 Magnesium ion binding site [ion binding]; other site 272560005161 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983 272560005162 Pfam match to entry PF00991 ParA, ParA family ATPase , score 18.8, E-value 2.8e-05 272560005163 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 272560005164 synthetase active site [active] 272560005165 NTP binding site [chemical binding]; other site 272560005166 metal binding site [ion binding]; metal-binding site 272560005167 Head-Tail Connector Protein gp6 of Bacteriophage HK97 and similar proteins; Region: gp6; cd08054 272560005168 oligomerization interface [polypeptide binding]; other site 272560005169 Phage portal protein; Region: Phage_portal; pfam04860 272560005170 Caudovirus prohead protease; Region: Peptidase_U35; pfam04586 272560005171 phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554 272560005172 Phage capsid family; Region: Phage_capsid; pfam05065 272560005173 Phage Terminase; Region: Terminase_1; cl19862 272560005174 Pfam match to entry PF03354 Phage_terminase, Phage Terminase , score 125.0, E-value 9.2e-35 272560005175 Signal peptide predicted for BPSL1144 by SignalP 2.0 HMM (Signal peptide probabilty 0.916) with cleavage site probability 0.483 between residues 22 and 23; signal peptide 272560005176 HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085 272560005177 active site 272560005178 Pfam match to entry PF01844 HNH, HNH endonuclease , score 38.0, E-value 1.4e-08 272560005179 Histidyl-tRNA synthetase; Region: PLN02972 272560005180 Helix-turn-helix domain; Region: HTH_39; pfam14090 272560005181 Helix-turn-helix domain; Region: HTH_17; cl17695 272560005182 integrase; Provisional; Region: PRK09692 272560005183 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560005184 active site 272560005185 DNA binding site [nucleotide binding] 272560005186 Int/Topo IB signature motif; other site 272560005187 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 29.6, E-value 9.7e-07 272560005188 ribonuclease G; Provisional; Region: PRK11712 272560005189 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 272560005190 homodimer interface [polypeptide binding]; other site 272560005191 oligonucleotide binding site [chemical binding]; other site 272560005192 Ribonuclease E/G family; Region: RNase_E_G; pfam10150 272560005193 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 36.7, E-value 3.4e-08 272560005194 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 272560005195 active site 272560005196 dimer interface [polypeptide binding]; other site 272560005197 Pfam match to entry PF02545 Maf, Maf-like protein , score 167.6, E-value 1.3e-47 272560005198 rRNA large subunit methyltransferase; Provisional; Region: PRK00103 272560005199 Pfam match to entry PF02590 DUF163, Uncharacterized ACR, COG1576 , score 187.1, E-value 1.8e-53 272560005200 iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090 272560005201 Pfam match to entry PF02410 DUF143, Domain of unknown function DUF143 , score 122.9, E-value 3.9e-34 272560005202 Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165 272560005203 active site 272560005204 (T/H)XGH motif; other site 272560005205 Pfam match to entry PF01467 CTP_transf_2, Cytidylyltransferase , score 21.9, E-value 8.3e-06 272560005206 coproporphyrinogen III oxidase; Provisional; Region: PRK05330 272560005207 Pfam match to entry PF01218 Coprogen_oxidas, Coproporphyrinogen III oxidase , score 592.2, E-value 2.1e-175 272560005208 PS01021 Coproporphyrinogen III oxidase signature. 272560005209 phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885 272560005210 Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844 272560005211 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071 272560005212 Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843 272560005213 Pfam match to entry PF02843 GARS_C, Phosphoribosylglycinamide synthetase, C domain , score 157.3, E-value 1.7e-44 272560005214 Pfam match to entry PF01071 GARS, Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain , score 275.5, E-value 4.6e-80 272560005215 Pfam match to entry PF02842 GARS_B, Phosphoribosylglycinamide synthetase, B domain , score 163.6, E-value 2.2e-46 272560005216 Pfam match to entry PF02844 GARS_N, Phosphoribosylglycinamide synthetase, N domain , score 198.3, E-value 7.7e-57 272560005217 hypothetical protein; Validated; Region: PRK00110 272560005218 Pfam match to entry PF01709 DUF28, Domain of unknown function DUF28 , score 413.4, E-value 1.4e-121 272560005219 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560005220 active site 272560005221 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 35.2, E-value 9.6e-08 272560005222 putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)-like, SDR; Region: BKR_like_SDR_like; cd05344 272560005223 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK12825 272560005224 putative NAD(P) binding site [chemical binding]; other site 272560005225 putative active site [active] 272560005226 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 177.8, E-value 1.1e-50 272560005227 Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422 272560005228 active site 272560005229 dimer interfaces [polypeptide binding]; other site 272560005230 catalytic residues [active] 272560005231 Pfam match to entry PF02142 MGS, MGS-like domain , score 85.2, E-value 8.9e-23 272560005232 PS01335 Methylglyoxal synthase active site. 272560005233 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 272560005234 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 272560005235 NADP binding site [chemical binding]; other site 272560005236 dimer interface [polypeptide binding]; other site 272560005237 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 297.1, E-value 1.4e-86 272560005238 1 probable transmembrane helix predicted for BPSL1170 by TMHMM2.0 at aa 5-24 272560005239 potassium-transporting ATPase subunit A; Provisional; Region: PRK05482 272560005240 10 probable transmembrane helices predicted for BPSL1171 by TMHMM2.0 at aa 5-27, 67-89, 133-155, 176-198, 285-307, 312-329, 412-434, 455-477, 522-544 and 565-587 272560005241 Pfam match to entry PF03814 KdpA, Potassium-transporting ATPase A subunit , score 1058.4, E-value 0 272560005242 PS00107 Protein kinases ATP-binding region signature. 272560005243 potassium-transporting ATPase subunit B; Provisional; Region: PRK01122 272560005244 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560005245 Soluble P-type ATPase [General function prediction only]; Region: COG4087 272560005246 7 probable transmembrane helices predicted for BPSL1172 by TMHMM2.0 at aa 59-81, 86-108, 247-269, 284-306, 612-634, 649-671 and 691-713 272560005247 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 206.5, E-value 2.7e-59 272560005248 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 114.0, E-value 1.9e-31 272560005249 PS00154 E1-E2 ATPases phosphorylation site. 272560005250 PS00018 EF-hand calcium-binding domain. 272560005251 potassium-transporting ATPase subunit C; Reviewed; Region: PRK00315 272560005252 Pfam match to entry PF02669 KdpC, K+-transporting ATPase, c chain , score 280.7, E-value 1.2e-81 272560005253 1 probable transmembrane helix predicted for BPSL1173 by TMHMM2.0 at aa 7-29 272560005254 sensor protein KdpD; Provisional; Region: PRK10490 272560005255 Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702 272560005256 USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987 272560005257 Ligand Binding Site [chemical binding]; other site 272560005258 Domain of unknown function (DUF4118); Region: DUF4118; pfam13493 272560005259 GAF domain; Region: GAF_3; pfam13492 272560005260 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560005261 dimer interface [polypeptide binding]; other site 272560005262 phosphorylation site [posttranslational modification] 272560005263 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560005264 ATP binding site [chemical binding]; other site 272560005265 Mg2+ binding site [ion binding]; other site 272560005266 G-X-G motif; other site 272560005267 Pfam match to entry PF02702 KdpD, Osmosensitive K+ channel His kinase sensor domain , score 584.2, E-value 5.2e-173 272560005268 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005269 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 67.9, E-value 1.4e-17 272560005270 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 105.3, E-value 7.5e-29 272560005271 DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529 272560005272 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560005273 active site 272560005274 phosphorylation site [posttranslational modification] 272560005275 intermolecular recognition site; other site 272560005276 dimerization interface [polypeptide binding]; other site 272560005277 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560005278 DNA binding site [nucleotide binding] 272560005279 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 133.5, E-value 2.4e-37 272560005280 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 95.9, E-value 5e-26 272560005281 Domain of unknown function (DUF333); Region: DUF333; pfam03891 272560005282 Pfam match to entry PF03891 DUF333, Domain of unknown function (DUF333) , score 46.6, E-value 3.6e-11 272560005283 Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910 272560005284 Pfam match to entry PF00893 DUF7, Integral membrane protein DUF7 , score 126.5, E-value 3.2e-35 272560005285 4 probable transmembrane helices predicted for BPSL1177 by TMHMM2.0 at aa 7-24, 34-53, 60-82 and 87-109 272560005286 Domain of unknown function (DUF4126); Region: DUF4126; pfam13548 272560005287 3 probable transmembrane helices predicted for BPSL1178 by TMHMM2.0 at aa 15-34, 41-63 and 148-170 272560005288 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127 272560005289 FtsX-like permease family; Region: FtsX; pfam02687 272560005290 10 probable transmembrane helices predicted for BPSL1179 by TMHMM2.0 at aa 35-57, 306-328, 349-371, 397-419, 440-462, 467-489, 517-539, 754-776, 808-830 and 843-865 272560005291 Pfam match to entry PF02687 DUF214, Predicted permease , score 50.0, E-value 3.5e-12 272560005292 Pfam match to entry PF02687 DUF214, Predicted permease , score 55.6, E-value 6.9e-14 272560005293 Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454 272560005294 apolar tunnel; other site 272560005295 heme binding site [chemical binding]; other site 272560005296 dimerization interface [polypeptide binding]; other site 272560005297 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872 272560005298 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469 272560005299 Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A) , score 23.6, E-value 2e-07 272560005300 Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A) , score 25.3, E-value 6.5e-08 272560005301 Bacterial protein of unknown function (DUF924); Region: DUF924; pfam06041 272560005302 amidase; Provisional; Region: PRK07042 272560005303 Pfam match to entry PF01425 Amidase, Amidase , score 280.4, E-value 1.6e-81 272560005304 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005305 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560005306 citrate-proton symporter; Provisional; Region: PRK15075 272560005307 putative substrate translocation pore; other site 272560005308 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 121.3, E-value 1.2e-33 272560005309 12 probable transmembrane helices predicted for BPSL1184 by TMHMM2.0 at aa 30-52, 62-84, 97-116, 121-143, 163-185, 200-217, 249-266, 281-303, 315-334, 344-366, 379-401 and 411-428 272560005310 PS00216 Sugar transport proteins signature 1. 272560005311 PS00217 Sugar transport proteins signature 2. 272560005312 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158 272560005313 13 probable transmembrane helices predicted for BPSL1185 by TMHMM2.0 at aa 61-83, 145-167, 174-193, 203-225, 237-254, 258-275, 282-304, 341-363, 375-394, 398-415, 428-449, 469-491 and 504-526 272560005314 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557 272560005315 classical (c) SDRs; Region: SDR_c; cd05233 272560005316 NAD(P) binding site [chemical binding]; other site 272560005317 active site 272560005318 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 238.4, E-value 6.8e-69 272560005319 PS00061 Short-chain dehydrogenases/reductases family signature. 272560005320 DNA recombination-mediator protein A; Region: DNA_processg_A; cl00695 272560005321 Pfam match to entry PF03641 Lysine_decarbox, Lysine decarboxylase , score 190.0, E-value 2.4e-54 272560005322 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560005323 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560005324 Bacterial transcriptional repressor; Region: TetR; pfam13972 272560005325 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 53.5, E-value 3.1e-13 272560005326 Predicted helix-turn-helix motif with score 1665.000, SD 4.86 at aa 29-50, sequence VTTTTIAEEMEISPGNLYYHFR 272560005327 Integral membrane diacylglycerol kinase; Region: DAGK_IM; cd14264 272560005328 putative active site [active] 272560005329 trimer interface [polypeptide binding]; other site 272560005330 putative active site [active] 272560005331 Zn binding site [ion binding]; other site 272560005332 1 probable transmembrane helix predicted for BPSL1189 by TMHMM2.0 at aa 154-176 272560005333 Pfam match to entry PF01219 DAGK_prokar, Prokaryotic diacylglycerol kinase , score 114.2, E-value 1.6e-31 272560005334 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560005335 This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814 272560005336 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 69.6, E-value 4.4e-18 272560005337 Signal peptide predicted for BPSL1191 by SignalP 2.0 HMM (Signal peptide probabilty 0.924) with cleavage site probability 0.754 between residues 30 and 31; signal peptide 272560005338 Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398 272560005339 putative active site [active] 272560005340 putative metal binding site [ion binding]; other site 272560005341 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 31.7, E-value 1.1e-06 272560005342 RDD family; Region: RDD; pfam06271 272560005343 4 probable transmembrane helices predicted for BPSL1192 by TMHMM2.0 at aa 7-29, 39-61, 82-104 and 108-130 272560005344 Signal peptide predicted for BPSL1193 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.942 between residues 22 and 23; signal peptide 272560005345 Protein of unknown function (DUF3106); Region: DUF3106; pfam11304 272560005346 Protein of unknown function (DUF3619); Region: DUF3619; pfam12279 272560005347 2 probable transmembrane helices predicted for BPSL1194 by TMHMM2.0 at aa 51-68 and 83-101 272560005348 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560005349 RNA polymerase factor sigma-70; Validated; Region: PRK09047 272560005350 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560005351 DNA binding residues [nucleotide binding] 272560005352 acetolactate synthase 3 catalytic subunit; Validated; Region: PRK06965 272560005353 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560005354 PYR/PP interface [polypeptide binding]; other site 272560005355 dimer interface [polypeptide binding]; other site 272560005356 TPP binding site [chemical binding]; other site 272560005357 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560005358 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 272560005359 TPP-binding site [chemical binding]; other site 272560005360 dimer interface [polypeptide binding]; other site 272560005361 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 317.8, E-value 8.2e-93 272560005362 PS00044 Bacterial regulatory proteins, lysR family signature. 272560005363 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 215.4, E-value 5.7e-62 272560005364 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 290.4, E-value 1.5e-84 272560005365 acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895 272560005366 N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878 272560005367 putative valine binding site [chemical binding]; other site 272560005368 dimer interface [polypeptide binding]; other site 272560005369 Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369 272560005370 PS00430 TonB-dependent receptor proteins signature 1. 272560005371 Pfam match to entry PF01842 ACT, ACT domain , score 64.3, E-value 1.7e-16 272560005372 ketol-acid reductoisomerase; Provisional; Region: PRK05479 272560005373 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991 272560005374 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 272560005375 Pfam match to entry PF01450 IlvC, Acetohydroxy acid isomeroreductase, catalytic domain , score 292.1, E-value 4.5e-85 272560005376 phosphatidylserine decarboxylase; Provisional; Region: PRK05305 272560005377 1 probable transmembrane helix predicted for BPSL1199 by TMHMM2.0 at aa 21-43 272560005378 Pfam match to entry PF02666 PS_Dcarbxylase, Phosphatidylserine decarboxylase , score 135.3, E-value 7e-38 272560005379 Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183 272560005380 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453 272560005381 6 probable transmembrane helices predicted for BPSL1200 by TMHMM2.0 at aa 48-70, 138-155, 167-189, 199-221, 233-250 and 254-276 272560005382 Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase , score 71.1, E-value 1.5e-18 272560005383 PS00379 CDP-alcohol phosphatidyltransferases signature. 272560005384 2-isopropylmalate synthase; Validated; Region: PRK00915 272560005385 2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940 272560005386 active site 272560005387 catalytic residues [active] 272560005388 metal binding site [ion binding]; metal-binding site 272560005389 LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917 272560005390 Pfam match to entry PF00682 HMGL-like, HMGL-like , score 431.9, E-value 3.7e-127 272560005391 PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 272560005392 PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 272560005393 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 272560005394 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 272560005395 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560005396 Pfam match to entry PF00916 Sulfate_transp, Sulfate transporter family , score 94.0, E-value 2e-25 272560005397 11 probable transmembrane helices predicted for BPSL1202 by TMHMM2.0 at aa 15-34, 41-63, 83-105, 110-132, 147-169, 182-204, 247-269, 289-308, 323-345, 352-371 and 386-408 272560005398 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883 272560005399 active site clefts [active] 272560005400 zinc binding site [ion binding]; other site 272560005401 dimer interface [polypeptide binding]; other site 272560005402 Pfam match to entry PF00484 Pro_CA, Carbonic anhydrase , score 151.9, E-value 7e-43 272560005403 PS00705 Prokaryotic-type carbonic anhydrases signature 2. 272560005404 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 272560005405 Signal peptide predicted for BPSL1204 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.653 between residues 28 and 29; signal peptide 272560005406 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005407 Signal peptide predicted for BPSL1205 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.631 between residues 28 and 29; signal peptide 272560005408 Periplasmic solute-binding domain of active transport proteins; Region: PBP1_SBP_like_3; cd06329 272560005409 putative ligand binding site [chemical binding]; other site 272560005410 Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353 272560005411 16S/18S rRNA binding site [nucleotide binding]; other site 272560005412 S13e-L30e interaction site [polypeptide binding]; other site 272560005413 25S rRNA binding site [nucleotide binding]; other site 272560005414 Pfam match to entry PF00312 Ribosomal_S15, Ribosomal protein S15 , score 139.0, E-value 5.4e-39 272560005415 PS00362 Ribosomal protein S15 signature. 272560005416 polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824 272560005417 Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363 272560005418 RNase E interface [polypeptide binding]; other site 272560005419 trimer interface [polypeptide binding]; other site 272560005420 Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726 272560005421 Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364 272560005422 RNase E interface [polypeptide binding]; other site 272560005423 trimer interface [polypeptide binding]; other site 272560005424 active site 272560005425 Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393 272560005426 putative nucleic acid binding region [nucleotide binding]; other site 272560005427 G-X-X-G motif; other site 272560005428 S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472 272560005429 RNA binding site [nucleotide binding]; other site 272560005430 domain interface; other site 272560005431 Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease, domain 1 , score 126.0, E-value 4.5e-35 272560005432 Pfam match to entry PF03725 RNase_PH_C, 3' exoribonuclease, domain 2 , score 61.4, E-value 1.3e-15 272560005433 Pfam match to entry PF03726 PNPase, Polyribonucleotide nucleotidyltransferase, RNA binding domain , score 92.8, E-value 4.5e-25 272560005434 Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease, domain 1 , score 185.3, E-value 6.3e-53 272560005435 Pfam match to entry PF03725 RNase_PH_C, 3' exoribonuclease, domain 2 , score 76.6, E-value 3.3e-20 272560005436 Pfam match to entry PF00013 KH, KH domain , score 47.3, E-value 2.2e-11 272560005437 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 78.9, E-value 7e-21 272560005438 putative NAD(P)H quinone oxidoreductase, PIG3 family; Region: quinone_pig3; TIGR02824 272560005439 PIG3 p53-inducible quinone oxidoreductase; Region: p53_inducible_oxidoreductase; cd05276 272560005440 NAD(P) binding site [chemical binding]; other site 272560005441 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 238.5, E-value 6.3e-69 272560005442 Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311 272560005443 substrate binding site [chemical binding]; other site 272560005444 dimer interface [polypeptide binding]; other site 272560005445 catalytic triad [active] 272560005446 Pfam match to entry PF00121 TIM, Triosephosphate isomerase , score 369.6, E-value 2.1e-108 272560005447 PS00171 Triosephosphate isomerase active site. 272560005448 PS00107 Protein kinases ATP-binding region signature. 272560005449 Preprotein translocase SecG subunit; Region: SecG; pfam03840 272560005450 Pfam match to entry PF03840 SecG, Preprotein translocase SecG subunit , score 99.8, E-value 3.5e-27 272560005451 2 probable transmembrane helices predicted for BPSL1210 by TMHMM2.0 at aa 2-19 and 48-70 272560005452 NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602 272560005453 3 probable transmembrane helices predicted for BPSL1211 by TMHMM2.0 at aa 2-24, 50-72 and 79-101 272560005454 Pfam match to entry PF00507 oxidored_q4, NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 , score 138.4, E-value 8.1e-39 272560005455 NADH dehydrogenase subunit B; Validated; Region: PRK06411 272560005456 Pfam match to entry PF01058 oxidored_q6, NADH ubiquinone oxidoreductase, 20 Kd subunit , score 218.1, E-value 8.4e-63 272560005457 PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 272560005458 NADH dehydrogenase subunit C; Provisional; Region: PRK06074 272560005459 Pfam match to entry PF00329 complex1_30Kd, Respiratory-chain NADH dehydrogenase, 30 Kd subunit , score 161.9, E-value 7.3e-46 272560005460 NADH dehydrogenase subunit D; Validated; Region: PRK06075 272560005461 Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261 272560005462 PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 272560005463 Pfam match to entry PF00346 complex1_49Kd, Respiratory-chain NADH dehydrogenase, 49 Kd subunit , score 520.1, E-value 1e-153 272560005464 NADH-quinone oxidoreductase, E subunit; Region: nuoE_fam; TIGR01958 272560005465 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064 272560005466 putative dimer interface [polypeptide binding]; other site 272560005467 [2Fe-2S] cluster binding site [ion binding]; other site 272560005468 Pfam match to entry PF01257 complex1_24kD, Respiratory-chain NADH dehydrogenase 24 Kd subunit , score 201.3, E-value 9.5e-58 272560005469 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894 272560005470 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 272560005471 SLBB domain; Region: SLBB; pfam10531 272560005472 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928 272560005473 Pfam match to entry PF01512 Complex1_51K, Respiratory-chain NADH dehydrogenase 51 Kd subunit , score 468.4, E-value 3.9e-138 272560005474 PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 272560005475 NADH dehydrogenase subunit G; Validated; Region: PRK09129 272560005476 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560005477 catalytic loop [active] 272560005478 iron binding site [ion binding]; other site 272560005479 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588 272560005480 MopB_NDH-1_NuoG2: The second domain of the NuoG subunit of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1), found in beta- and gammaproteobacteria. The NDH-1 is the first energy-transducting complex in the respiratory chain and functions as...; Region: MopB_NDH-1_NuoG2; cd02772 272560005481 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 44.5, E-value 1.6e-10 272560005482 PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 272560005483 PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 272560005484 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score -106.6, E-value 3.1e-10 272560005485 NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076 272560005486 Pfam match to entry PF00146 NADHdh, NADH dehydrogenase , score 503.6, E-value 9.7e-149 272560005487 8 probable transmembrane helices predicted for BPSL1218 by TMHMM2.0 at aa 23-45, 89-111, 126-148, 168-190, 205-224, 255-277, 287-309 and 330-352 272560005488 PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 272560005489 NADH dehydrogenase subunit I; Provisional; Region: PRK05888 272560005490 4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484 272560005491 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 26.8, E-value 1.1e-05 272560005492 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560005493 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 33.7, E-value 2.8e-07 272560005494 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560005495 NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638 272560005496 Pfam match to entry PF00499 oxidored_q3, NADH-ubiquinone/plastoquinone oxidoreductase chain 6 , score 80.4, E-value 2.5e-21 272560005497 5 probable transmembrane helices predicted for BPSL1220 by TMHMM2.0 at aa 4-23, 30-49, 53-75, 88-110 and 147-169 272560005498 NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715 272560005499 Pfam match to entry PF00420 oxidored_q2, NADH-ubiquinone/plastoquinone oxidoreductase chain 4L , score 130.2, E-value 2.5e-36 272560005500 3 probable transmembrane helices predicted for BPSL1221 by TMHMM2.0 at aa 5-24, 29-51 and 61-83 272560005501 NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590 272560005502 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662 272560005503 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 272560005504 16 probable transmembrane helices predicted for BPSL1222 by TMHMM2.0 at aa 10-32, 39-61, 81-103, 116-135, 140-162, 175-197, 212-234, 255-277, 287-309, 316-338, 342-364, 385-404, 424-446, 488-510, 553-575 and 654-676 272560005505 Pfam match to entry PF00662 oxidored_q1_N, NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus , score 105.0, E-value 9.7e-29 272560005506 Pfam match to entry PF00361 oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains , score 359.4, E-value 2.5e-105 272560005507 NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846 272560005508 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 272560005509 14 probable transmembrane helices predicted for BPSL1223 by TMHMM2.0 at aa 4-26, 33-55, 86-108, 115-133, 137-159, 166-188, 203-221, 241-263, 273-295, 302-324, 329-351, 372-394, 404-426 and 447-469 272560005510 Pfam match to entry PF00361 oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains , score 344.6, E-value 7.3e-101 272560005511 NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777 272560005512 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 272560005513 14 probable transmembrane helices predicted for BPSL1224 by TMHMM2.0 at aa 5-24, 36-55, 70-92, 105-122, 126-148, 161-183, 203-225, 238-260, 275-292, 299-321, 334-356, 376-398, 413-435 and 457-479 272560005514 Pfam match to entry PF00361 oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains , score 259.8, E-value 2.4e-75 272560005515 Protein of unknown function (DUF2818); Region: DUF2818; pfam10993 272560005516 3 probable transmembrane helices predicted for BPSL1225 by TMHMM2.0 at aa 4-21, 42-61 and 76-98 272560005517 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 272560005518 dimer interface [polypeptide binding]; other site 272560005519 ADP-ribose binding site [chemical binding]; other site 272560005520 active site 272560005521 nudix motif; other site 272560005522 metal binding site [ion binding]; metal-binding site 272560005523 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 75.1, E-value 9.8e-20 272560005524 PS00893 mutT domain signature. 272560005525 Protein of unknown function (DUF1178); Region: DUF1178; pfam06676 272560005526 pimeloyl-CoA dehydrogenase, large subunit; Region: pimC_large; TIGR03204 272560005527 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560005528 active site 272560005529 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 86.0, E-value 5e-23 272560005530 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 57.0, E-value 2.7e-14 272560005531 pimeloyl-CoA dehydrogenase, small subunit; Region: pimD_small; TIGR03203 272560005532 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 272560005533 active site 272560005534 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 20.9, E-value 1.3e-05 272560005535 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 74.1, E-value 1.9e-19 272560005536 YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454 272560005537 putative active site [active] 272560005538 putative catalytic site [active] 272560005539 Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain , score 43.8, E-value 2.5e-10 272560005540 NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their...; Region: NodN; cd03450 272560005541 putative active site [active] 272560005542 putative catalytic site [active] 272560005543 Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain , score 108.5, E-value 8.2e-30 272560005544 Signal peptide predicted for BPSL1232 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.970 between residues 51 and 52; signal peptide 272560005545 Pectate lyase superfamily protein; Region: Pectate_lyase_3; cl19188 272560005546 Right handed beta helix region; Region: Beta_helix; pfam13229 272560005547 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005548 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560005549 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560005550 active site 272560005551 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 195.0, E-value 7.4e-56 272560005552 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560005553 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 46.2, E-value 4.8e-11 272560005554 Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154 272560005555 putative active site [active] 272560005556 putative substrate binding site [chemical binding]; other site 272560005557 ATP binding site [chemical binding]; other site 272560005558 Pfam match to entry PF01636 APH, Phosphotransferase enzyme family , score 194.5, E-value 1.1e-55 272560005559 PS00109 Tyrosine protein kinases specific active-site signature. 272560005560 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 272560005561 catalytic core [active] 272560005562 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score 3.4, E-value 9e-12 272560005563 enoyl-CoA hydratase; Provisional; Region: PRK07511 272560005564 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560005565 substrate binding site [chemical binding]; other site 272560005566 oxyanion hole (OAH) forming residues; other site 272560005567 trimer interface [polypeptide binding]; other site 272560005568 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 149.9, E-value 2.9e-42 272560005569 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560005570 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560005571 Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570 272560005572 C-terminal domain interface [polypeptide binding]; other site 272560005573 GSH binding site (G-site) [chemical binding]; other site 272560005574 dimer interface [polypeptide binding]; other site 272560005575 C-terminal, alpha helical domain of an unknown subfamily 9 of Glutathione S-transferases; Region: GST_C_9; cd10424 272560005576 putative N-terminal domain interface [polypeptide binding]; other site 272560005577 putative dimer interface [polypeptide binding]; other site 272560005578 putative substrate binding pocket (H-site) [chemical binding]; other site 272560005579 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 28.0, E-value 1.4e-05 272560005580 methionine aminotransferase; Validated; Region: PRK09082 272560005581 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560005582 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560005583 homodimer interface [polypeptide binding]; other site 272560005584 catalytic residue [active] 272560005585 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 85.7, E-value 6.3e-23 272560005586 PIN domain; Region: PIN_3; pfam13470 272560005587 PIN domain; Region: PIN_3; cl17397 272560005588 Pfam match to entry PF01850 PIN, PIN domain , score 14.3, E-value 0.00048 272560005589 hypothetical protein; Validated; Region: PRK02101 272560005590 Pfam match to entry PF03883 DUF328, Protein of unknown function (DUF328) , score 478.0, E-value 4.9e-141 272560005591 Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866 272560005592 Peptidase M14-like domain of ATP/GTP binding proteins and cytosolic carboxypeptidases; uncharacterized bacterial subgroup; Region: M14_Nna1_like_1; cd06234 272560005593 putative active site [active] 272560005594 Zn binding site [ion binding]; other site 272560005595 Signal peptide predicted for BPSL1243 by SignalP 2.0 HMM (Signal peptide probabilty 0.929) with cleavage site probability 0.925 between residues 47 and 48; signal peptide 272560005596 DNA topoisomerase III; Validated; Region: PRK08173 272560005597 Predicted membrane protein [Function unknown]; Region: COG3235 272560005598 6 probable transmembrane helices predicted for BPSL1244 by TMHMM2.0 at aa 10-29, 41-63, 78-100, 107-126, 146-168 and 181-203 272560005599 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560005600 active site 272560005601 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078 272560005602 phosphorylation site [posttranslational modification] 272560005603 intermolecular recognition site; other site 272560005604 dimerization interface [polypeptide binding]; other site 272560005605 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560005606 DNA binding residues [nucleotide binding] 272560005607 dimerization interface [polypeptide binding]; other site 272560005608 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 59.6, E-value 4.5e-15 272560005609 Predicted helix-turn-helix motif with score 1512.000, SD 4.34 at aa 197-218, sequence STNKMIARTLGISEGTVKIHLA 272560005610 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score -6.5, E-value 0.0017 272560005611 Protein of unknown function (DUF2863); Region: DUF2863; pfam11062 272560005612 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 272560005613 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 272560005614 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279 272560005615 active site 272560005616 Pfam match to entry PF00557 Peptidase_M24, metallopeptidase M24 , score 67.0, E-value 2.7e-17 272560005617 PS00491 Aminopeptidase P and proline dipeptidase signature. 272560005618 PS00294 Prenyl group binding site (CAAX box). 272560005619 Fatty acid desaturase [Lipid metabolism]; Region: DesA; COG3239 272560005620 The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cd01060 272560005621 putative di-iron ligands [ion binding]; other site 272560005622 5 probable transmembrane helices predicted for BPSL1248 by TMHMM2.0 at aa 40-62, 99-116, 207-229, 244-266 and 287-309 272560005623 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 272560005624 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560005625 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560005626 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 11.7, E-value 0.14 272560005627 Predicted helix-turn-helix motif with score 1549.000, SD 4.46 at aa 264-285, sequence PSLDALARELHLSERTLKRKLS 272560005628 PS00041 Bacterial regulatory proteins, araC family signature. 272560005629 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 54.2, E-value 1.9e-13 272560005630 D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790 272560005631 Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176 272560005632 ligand binding site [chemical binding]; other site 272560005633 NAD binding site [chemical binding]; other site 272560005634 tetramer interface [polypeptide binding]; other site 272560005635 catalytic site [active] 272560005636 C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901 272560005637 L-serine binding site [chemical binding]; other site 272560005638 ACT domain interface; other site 272560005639 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 48.5, E-value 9.6e-12 272560005640 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 233.8, E-value 1.5e-67 272560005641 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560005642 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 272560005643 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 272560005644 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560005645 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560005646 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 272560005647 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560005648 substrate binding pocket [chemical binding]; other site 272560005649 membrane-bound complex binding site; other site 272560005650 hinge residues; other site 272560005651 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 272560005652 Coiled-coil domain-containing protein 50 N-terminus; Region: CCDC50_N; pfam15295 272560005653 Histidine kinase; Region: HisKA_3; pfam07730 272560005654 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560005655 ATP binding site [chemical binding]; other site 272560005656 Mg2+ binding site [ion binding]; other site 272560005657 G-X-G motif; other site 272560005658 8 probable transmembrane helices predicted for BPSL1253 by TMHMM2.0 at aa 24-46, 56-78, 85-107, 122-144, 157-179, 199-218, 225-247 and 257-276 272560005659 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 60.9, E-value 1.8e-15 272560005660 Bacterial aspartate proteases, retropepsin-like protease family; Region: retropepsin_like_bacteria; cd05483 272560005661 catalytic motif [active] 272560005662 Catalytic residue [active] 272560005663 Aspartyl protease; Region: Asp_protease_2; pfam13650 272560005664 PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117 272560005665 Signal peptide predicted for BPSL1256 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 24 and 25; signal peptide 272560005666 Cytochrome c; Region: Cytochrom_C; cl11414 272560005667 Cytochrome c; Region: Cytochrom_C; cl11414 272560005668 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560005669 PS00190 Cytochrome c family heme-binding site signature. 272560005670 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score -0.1, E-value 0.028 272560005671 PS00190 Cytochrome c family heme-binding site signature. 272560005672 Signal peptide predicted for BPSL1257 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 36 and 37; signal peptide 272560005673 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560005674 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560005675 Cytochrome c; Region: Cytochrom_C; pfam00034 272560005676 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 6.4, E-value 0.0061 272560005677 PS00190 Cytochrome c family heme-binding site signature. 272560005678 PS00190 Cytochrome c family heme-binding site signature. 272560005679 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 37.0, E-value 2.8e-08 272560005680 PS00190 Cytochrome c family heme-binding site signature. 272560005681 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005682 1 probable transmembrane helix predicted for BPSL1258 by TMHMM2.0 at aa 32-54 272560005683 Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622 272560005684 Cupredoxin superfamily; Region: Cupredoxin; cl19115 272560005685 1 probable transmembrane helix predicted for BPSL1259 by TMHMM2.0 at aa 23-45 272560005686 PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 272560005687 ba3-like heme-copper oxidase subunit I. The ba3 family of heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and some archaea which catalyze the reduction of O2 and simultaneously pump protons across the...; Region: ba3-like_Oxidase_I; cd01660 272560005688 Putative D-pathway homolog; other site 272560005689 Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115 272560005690 Low-spin heme binding site [chemical binding]; other site 272560005691 Subunit I/II interface [polypeptide binding]; other site 272560005692 Putative Q-pathway; other site 272560005693 Putative alternate electron transfer pathway; other site 272560005694 Putative water exit pathway; other site 272560005695 Binuclear center (active site) [active] 272560005696 Putative K-pathway homolog; other site 272560005697 Putative proton exit pathway; other site 272560005698 Subunit I/IIa interface [polypeptide binding]; other site 272560005699 Electron transfer pathway; other site 272560005700 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score -68.0, E-value 1.1e-10 272560005701 13 probable transmembrane helices predicted for BPSL1260 by TMHMM2.0 at aa 7-29, 56-78, 91-113, 128-150, 171-193, 208-230, 251-268, 283-305, 325-347, 362-384, 405-427, 447-469 and 502-524 272560005702 Cytochrome c553 [Energy production and conversion]; Region: COG2863 272560005703 Cytochrome c; Region: Cytochrom_C; cl11414 272560005704 1 probable transmembrane helix predicted for BPSL1261 by TMHMM2.0 at aa 13-35 272560005705 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 26.9, E-value 3.1e-05 272560005706 PS00190 Cytochrome c family heme-binding site signature. 272560005707 PS00190 Cytochrome c family heme-binding site signature. 272560005708 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215 272560005709 PAS domain; Region: PAS_9; pfam13426 272560005710 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560005711 putative active site [active] 272560005712 heme pocket [chemical binding]; other site 272560005713 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560005714 metal binding site [ion binding]; metal-binding site 272560005715 active site 272560005716 I-site; other site 272560005717 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560005718 Pfam match to entry PF00563 EAL, EAL domain , score 391.4, E-value 5.9e-115 272560005719 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 124.8, E-value 1.1e-34 272560005720 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 272560005721 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 272560005722 catalytic triad [active] 272560005723 2 probable transmembrane helices predicted for BPSL1264 by TMHMM2.0 at aa 5-24 and 57-79 272560005724 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 87.2, E-value 2.2e-23 272560005725 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702 272560005726 atypical (a) SDRs, subgroup 5; Region: SDR_a5; cd05243 272560005727 NAD(P) binding site [chemical binding]; other site 272560005728 putative active site [active] 272560005729 multidrug efflux system subunit MdtC; Provisional; Region: PRK10614 272560005730 MMPL family; Region: MMPL; cl14618 272560005731 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1171.2, E-value 0 272560005732 10 probable transmembrane helices predicted for BPSL1266 by TMHMM2.0 at aa 7-29, 336-353, 360-382, 434-456, 463-485, 527-549, 922-944, 964-986, 1016-1038 and 1053-1075 272560005733 multidrug efflux system subunit MdtB; Provisional; Region: PRK10503 272560005734 MMPL family; Region: MMPL; cl14618 272560005735 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1249.4, E-value 0 272560005736 10 probable transmembrane helices predicted for BPSL1267 by TMHMM2.0 at aa 7-29, 334-353, 360-382, 431-453, 460-482, 529-548, 858-880, 900-922, 953-975 and 990-1012 272560005737 PS00152 ATP synthase alpha and beta subunits signature. 272560005738 multidrug efflux system subunit MdtA; Provisional; Region: PRK11556 272560005739 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560005740 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560005741 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 96.6, E-value 3.3e-26 272560005742 1 probable transmembrane helix predicted for BPSL1268 by TMHMM2.0 at aa 28-45 272560005743 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560005744 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560005745 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560005746 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 59.9, E-value 3.7e-15 272560005747 Predicted helix-turn-helix motif with score 1795.000, SD 5.30 at aa 41-62, sequence VSNRELAELTGIPKPTVSRITA 272560005748 Signal peptide predicted for BPSL1270 by SignalP 2.0 HMM (Signal peptide probabilty 0.877) with cleavage site probability 0.640 between residues 60 and 61; signal peptide 272560005749 Bacterial protein of unknown function (DUF839); Region: DUF839; pfam05787 272560005750 Predicted transcriptional regulator [Transcription]; Region: COG1959 272560005751 Rrf2 family protein; Region: rrf2_super; TIGR00738 272560005752 Pfam match to entry PF02082 UPF0074, Uncharacterized protein family UPF0074 , score 25.0, E-value 4.6e-08 272560005753 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560005754 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560005755 Signal peptide predicted for BPSL1273 by SignalP 2.0 HMM (Signal peptide probabilty 0.953) with cleavage site probability 0.865 between residues 17 and 18; signal peptide 272560005756 NAD(P) binding site [chemical binding]; other site 272560005757 active site 272560005758 Cysteine dioxygenase type I; Region: CDO_I; pfam05995 272560005759 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560005760 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560005761 putative DNA binding site [nucleotide binding]; other site 272560005762 putative Zn2+ binding site [ion binding]; other site 272560005763 AsnC family; Region: AsnC_trans_reg; pfam01037 272560005764 Predicted helix-turn-helix motif with score 1519.000, SD 4.36 at aa 34-55, sequence LPIAELAQRVNLSQTPCWKRIQ 272560005765 PS00519 Bacterial regulatory proteins, asnC family signature. 272560005766 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 155.6, E-value 5.4e-44 272560005767 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 272560005768 sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968 272560005769 Walker A/P-loop; other site 272560005770 ATP binding site [chemical binding]; other site 272560005771 Q-loop/lid; other site 272560005772 ABC transporter signature motif; other site 272560005773 Walker B; other site 272560005774 D-loop; other site 272560005775 H-loop/switch region; other site 272560005776 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 204.4, E-value 1.1e-58 272560005777 PS00211 ABC transporters family signature. 272560005778 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005779 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 272560005780 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560005781 dimer interface [polypeptide binding]; other site 272560005782 conserved gate region; other site 272560005783 putative PBP binding loops; other site 272560005784 ABC-ATPase subunit interface; other site 272560005785 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560005786 dimer interface [polypeptide binding]; other site 272560005787 conserved gate region; other site 272560005788 putative PBP binding loops; other site 272560005789 ABC-ATPase subunit interface; other site 272560005790 11 probable transmembrane helices predicted for BPSL1277 by TMHMM2.0 at aa 38-60, 80-102, 114-136, 168-190, 210-232, 264-286, 307-329, 356-378, 399-421, 436-455 and 544-566 272560005791 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 25.3, E-value 9e-05 272560005792 PS00216 Sugar transport proteins signature 1. 272560005793 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 61.5, E-value 1.1e-15 272560005794 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560005795 Signal peptide predicted for BPSL1278 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 32 and 33; signal peptide 272560005796 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 272560005797 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 22.7, E-value 2.5e-06 272560005798 1 probable transmembrane helix predicted for BPSL1279 by TMHMM2.0 at aa 12-34 272560005799 putative proline-specific permease; Provisional; Region: proY; PRK10580 272560005800 Spore germination protein; Region: Spore_permease; cl17796 272560005801 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 478.8, E-value 2.9e-141 272560005802 12 probable transmembrane helices predicted for BPSL1280 by TMHMM2.0 at aa 37-54, 58-80, 118-140, 145-167, 174-196, 216-238, 266-288, 308-330, 353-375, 379-401, 421-443 and 448-470 272560005803 PS00218 Amino acid permeases signature. 272560005804 Predicted membrane protein [Function unknown]; Region: COG1289 272560005805 FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805 272560005806 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 272560005807 8 probable transmembrane helices predicted for BPSL1281 by TMHMM2.0 at aa 15-37, 42-59, 69-86, 91-113, 133-155, 414-436, 451-468 and 489-511 272560005808 Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; pfam04257 272560005809 exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450 272560005810 exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609 272560005811 UvrD-like helicase C-terminal domain; Region: UvrD_C_2; cl19402 272560005812 PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705 272560005813 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase , score 211.1, E-value 1.1e-60 272560005814 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005815 AAA domain; Region: AAA_30; pfam13604 272560005816 UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538 272560005817 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005818 PS00583 pfkB family of carbohydrate kinases signature 1. 272560005819 Pfam match to entry PF01443 Viral_helicase1, Viral (Superfamily 1) RNA helicase , score 24.2, E-value 1.8e-07 272560005820 hypothetical protein; Provisional; Region: PRK09256 272560005821 Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain , score 91.7, E-value 9.9e-25 272560005822 PS00745 Prokaryotic-type class I peptide chain release factors signature. 272560005823 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560005824 Pfam match to entry PF00563 EAL, EAL domain , score 122.0, E-value 7.1e-34 272560005825 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560005826 EamA-like transporter family; Region: EamA; pfam00892 272560005827 EamA-like transporter family; Region: EamA; pfam00892 272560005828 10 probable transmembrane helices predicted for BPSL1287 by TMHMM2.0 at aa 5-27, 37-56, 69-91, 95-117, 122-141, 156-178, 191-213, 218-240, 247-269 and 274-296 272560005829 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 80.8, E-value 1.9e-21 272560005830 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 73.3, E-value 3.2e-19 272560005831 Signal peptide predicted for BPSL1288 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.468 between residues 32 and 33; signal peptide 272560005832 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005833 Signal peptide predicted for BPSL1289 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.861 between residues 22 and 23; signal peptide 272560005834 1 probable transmembrane helix predicted for BPSL1289 by TMHMM2.0 at aa 33-55 272560005835 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005836 thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284 272560005837 ThiC-associated domain; Region: ThiC-associated; pfam13667 272560005838 ThiC family; Region: ThiC; pfam01964 272560005839 Pfam match to entry PF01964 ThiC, ThiC family , score 1138.8, E-value 0 272560005840 Signal peptide predicted for BPSL1291 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 between residues 23 and 24; signal peptide 272560005841 pentapeptide MXKDX repeat protein; Region: penta_MxKDx; TIGR02953 272560005842 4 probable transmembrane helices predicted for BPSL1293 by TMHMM2.0 at aa 92-114, 141-163, 208-227 and 247-269 272560005843 Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041 272560005844 Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199 272560005845 Moco binding site; other site 272560005846 metal coordination site [ion binding]; other site 272560005847 Pfam match to entry PF00174 oxidored_molyb, Oxidoreductase molybdopterin binding domain , score -87.8, E-value 2e-05 272560005848 putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272 272560005849 EamA-like transporter family; Region: EamA; pfam00892 272560005850 EamA-like transporter family; Region: EamA; pfam00892 272560005851 10 probable transmembrane helices predicted for BPSL1295 by TMHMM2.0 at aa 26-48, 53-72, 85-107, 111-133, 140-159, 169-191, 196-218, 228-250, 257-279 and 284-303 272560005852 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 60.0, E-value 3.5e-15 272560005853 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 59.7, E-value 4e-15 272560005854 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560005855 putative substrate translocation pore; other site 272560005856 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560005857 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -77.1, E-value 4e-05 272560005858 12 probable transmembrane helices predicted for BPSL1296 by TMHMM2.0 at aa 13-35, 55-77, 84-103, 107-129, 142-164, 168-190, 224-246, 256-278, 285-302, 306-325, 345-367 and 371-393 272560005859 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560005860 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560005861 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560005862 Repeat of Unknown Function (DUF347); Region: DUF347; pfam03988 272560005863 8 probable transmembrane helices predicted for BPSL1297 by TMHMM2.0 at aa 7-29, 44-66, 73-92, 102-124, 143-162, 167-189, 196-215 and 230-252 272560005864 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 44.7, E-value 1.4e-10 272560005865 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 61.4, E-value 1.3e-15 272560005866 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 28.1, E-value 1.3e-05 272560005867 Pfam match to entry PF03988 DUF347, Repeat of Unknown Function (DUF347) , score 69.3, E-value 5.3e-18 272560005868 signal peptide - predicted by PSORT 272560005869 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560005870 Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402 272560005871 active site 272560005872 metal binding site [ion binding]; metal-binding site 272560005873 hexamer interface [polypeptide binding]; other site 272560005874 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 68.1, E-value 1.3e-17 272560005875 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 272560005876 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560005877 Walker A/P-loop; other site 272560005878 ATP binding site [chemical binding]; other site 272560005879 Q-loop/lid; other site 272560005880 ABC transporter signature motif; other site 272560005881 Walker B; other site 272560005882 D-loop; other site 272560005883 H-loop/switch region; other site 272560005884 TOBE domain; Region: TOBE_2; pfam08402 272560005885 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 236.3, E-value 2.9e-68 272560005886 PS00211 ABC transporters family signature. 272560005887 PS00017 ATP/GTP-binding site motif A (P-loop). 272560005888 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560005889 dimer interface [polypeptide binding]; other site 272560005890 conserved gate region; other site 272560005891 putative PBP binding loops; other site 272560005892 ABC-ATPase subunit interface; other site 272560005893 6 probable transmembrane helices predicted for BPSL1301 by TMHMM2.0 at aa 36-58, 96-118, 131-150, 160-182, 218-240 and 265-287 272560005894 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 36.2, E-value 5e-08 272560005895 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560005896 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560005897 dimer interface [polypeptide binding]; other site 272560005898 conserved gate region; other site 272560005899 putative PBP binding loops; other site 272560005900 ABC-ATPase subunit interface; other site 272560005901 6 probable transmembrane helices predicted for BPSL1302 by TMHMM2.0 at aa 12-34, 63-85, 94-116, 136-158, 198-220 and 240-262 272560005902 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 44.3, E-value 1.8e-10 272560005903 Signal peptide predicted for BPSL1303 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 41 and 42; signal peptide 272560005904 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560005905 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 272560005906 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 50.8, E-value 2e-12 272560005907 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560005908 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560005909 DNA binding site [nucleotide binding] 272560005910 domain linker motif; other site 272560005911 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 272560005912 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 69.4, E-value 4.8e-18 272560005913 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family , score 40.6, E-value 2.3e-09 272560005914 Predicted helix-turn-helix motif with score 1716.000, SD 5.03 at aa 3-24, sequence PTIKDVAALAGFSIATVSRAIN 272560005915 Signal peptide predicted for BPSL1303 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 34 and 35; signal peptide 272560005916 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 272560005917 4 probable transmembrane helices predicted for BPSL1305 by TMHMM2.0 at aa 40-62, 94-116, 129-151 and 166-188 272560005918 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560005919 metal binding site [ion binding]; metal-binding site 272560005920 active site 272560005921 I-site; other site 272560005922 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 206.1, E-value 3.4e-59 272560005923 8 probable transmembrane helices predicted for BPSL1306 by TMHMM2.0 at aa 9-31, 46-68, 73-95, 100-122, 143-165, 175-192, 199-218 and 228-250 272560005924 Protein of unknown function (DUF1326); Region: DUF1326; pfam07040 272560005925 Predicted metal-binding integral membrane protein (DUF2182); Region: DUF2182; pfam09948 272560005926 5 probable transmembrane helices predicted for BPSL1308 by TMHMM2.0 at aa 57-79, 92-114, 129-151, 199-221 and 231-253 272560005927 Transcriptional regulator [Transcription]; Region: PaiB; COG2808 272560005928 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560005929 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560005930 DNA-binding site [nucleotide binding]; DNA binding site 272560005931 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560005932 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560005933 homodimer interface [polypeptide binding]; other site 272560005934 catalytic residue [active] 272560005935 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 51.7, E-value 1e-12 272560005936 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 22.3, E-value 2.3e-06 272560005937 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560005938 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560005939 putative DNA binding site [nucleotide binding]; other site 272560005940 putative Zn2+ binding site [ion binding]; other site 272560005941 AsnC family; Region: AsnC_trans_reg; pfam01037 272560005942 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 96.7, E-value 2.9e-26 272560005943 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 272560005944 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 272560005945 glutaminase active site [active] 272560005946 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 272560005947 dimer interface [polypeptide binding]; other site 272560005948 active site 272560005949 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 272560005950 dimer interface [polypeptide binding]; other site 272560005951 active site 272560005952 PS00443 Glutamine amidotransferases class-II active site. 272560005953 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 204.5, E-value 1.1e-58 272560005954 Pfam match to entry PF01380 SIS, SIS domain , score 117.7, E-value 1.5e-32 272560005955 Pfam match to entry PF01380 SIS, SIS domain , score 96.6, E-value 3.1e-26 272560005956 Retinal pigment epithelial membrane protein; Region: RPE65; pfam03055 272560005957 Pfam match to entry PF03055 RPE65, Retinal pigment epithelial membrane protein , score 332.9, E-value 2.3e-97 272560005958 Uncharacterized protein conserved in bacteria (DUF2239); Region: DUF2239; pfam09998 272560005959 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560005960 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560005961 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 272560005962 putative effector binding pocket; other site 272560005963 putative dimerization interface [polypeptide binding]; other site 272560005964 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 160.0, E-value 2.6e-45 272560005965 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 74.1, E-value 1.9e-19 272560005966 PS00044 Bacterial regulatory proteins, lysR family signature. 272560005967 Predicted helix-turn-helix motif with score 1468.000, SD 4.19 at aa 45-66, sequence ANFTRAADTLGMPRSSVSAAIQ 272560005968 short chain dehydrogenase; Provisional; Region: PRK12744 272560005969 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560005970 NAD(P) binding site [chemical binding]; other site 272560005971 active site 272560005972 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 78.1, E-value 1.2e-20 272560005973 Signal peptide predicted for BPSL1317 by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.525 between residues 29 and 30; signal peptide 272560005974 Uncharacterized protein conserved in bacteria (DUF2242); Region: DUF2242; pfam10001 272560005975 region rich in alanine, proline, serine and threonine amino acid residues. Also high G+C content (81.23%) 272560005976 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560005977 Bacterial protein of unknown function (DUF934); Region: DUF934; pfam06073 272560005978 Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155 272560005979 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560005980 Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077 272560005981 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560005982 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560005983 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain , score 62.7, E-value 5.1e-16 272560005984 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 51.2, E-value 1.4e-12 272560005985 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 57.0, E-value 2.7e-14 272560005986 Protein of unknown function (DUF2970); Region: DUF2970; pfam11174 272560005987 1 probable transmembrane helix predicted for BPSL1320 by TMHMM2.0 at aa 34-56 272560005988 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560005989 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560005990 DNA-binding site [nucleotide binding]; DNA binding site 272560005991 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560005992 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560005993 homodimer interface [polypeptide binding]; other site 272560005994 catalytic residue [active] 272560005995 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 49.4, E-value 5.2e-12 272560005996 Predicted helix-turn-helix motif with score 974.000, SD 2.50 at aa 423-444, sequence LEFPDAIDAMGLHREAIRRGVS 272560005997 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 37.1, E-value 2.5e-08 272560005998 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 272560005999 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 272560006000 putative dimer interface [polypeptide binding]; other site 272560006001 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family , score 71.7, E-value 1e-18 272560006002 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 272560006003 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 272560006004 putative dimer interface [polypeptide binding]; other site 272560006005 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family , score 71.8, E-value 9.1e-19 272560006006 Cysteine-rich 4 helical bundle widely conserved in bacteria; Region: DUF326; cd08026 272560006007 dimerization interface [polypeptide binding]; other site 272560006008 Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819 272560006009 active site 272560006010 substrate-binding site [chemical binding]; other site 272560006011 metal-binding site [ion binding] 272560006012 GTP binding site [chemical binding]; other site 272560006013 Pfam match to entry PF00821 PEPCK, Phosphoenolpyruvate carboxykinase , score 1295.7, E-value 0 272560006014 PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 272560006015 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK07066 272560006016 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560006017 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560006018 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 83.0, E-value 3.9e-22 272560006019 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 37.5, E-value 2e-08 272560006020 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560006021 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560006022 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560006023 dimerization interface [polypeptide binding]; other site 272560006024 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 108.7, E-value 7.3e-30 272560006025 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 88.6, E-value 8.2e-24 272560006026 PS00044 Bacterial regulatory proteins, lysR family signature. 272560006027 Predicted helix-turn-helix motif with score 2034.000, SD 6.11 at aa 58-79, sequence GSFTAASERVSLSQSTVSQHIR 272560006028 Malonate transporter MadL subunit; Region: MadL; cl04273 272560006029 Pfam match to entry PF03817 MadL, Malonate transporter MadL subunit , score 240.8, E-value 1.3e-69 272560006030 4 probable transmembrane helices predicted for BPSL1327 by TMHMM2.0 at aa 7-29, 33-50, 63-80 and 90-112 272560006031 Malonate/sodium symporter MadM subunit; Region: MadM; cl04274 272560006032 Pfam match to entry PF03818 MadM, Malonate/sodium symporter MadM subunit , score 83.7, E-value 2.5e-22 272560006033 8 probable transmembrane helices predicted for BPSL1328 by TMHMM2.0 at aa 5-27, 34-56, 66-88, 101-123, 133-155, 162-184, 194-213 and 220-242 272560006034 malonate decarboxylase, alpha subunit; Region: mdcA; TIGR01110 272560006035 Coenzyme A transferase; Region: CoA_trans; cl17247 272560006036 malonate decarboxylase subunit delta; Provisional; Region: PRK02103 272560006037 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189 272560006038 malonate decarboxylase, gamma subunit; Region: malonate_gamma; TIGR03134 272560006039 phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK02098 272560006040 ATP:dephospho-CoA triphosphoribosyl transferase; Region: CitG; cl00768 272560006041 Pfam match to entry PF01874 CitG, ATP:dephospho-CoA triphosphoribosyl transferase , score 119.6, E-value 3.9e-33 272560006042 malonate decarboxylase, epsilon subunit; Region: malonate_mdcH; TIGR03131 272560006043 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score -7.6, E-value 1.1e-10 272560006044 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 272560006045 PLD-like domain; Region: PLDc_2; pfam13091 272560006046 putative active site [active] 272560006047 catalytic site [active] 272560006048 Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757 272560006049 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560006050 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560006051 Glutathione S-transferase, N-terminal domain; Region: GST_N_3; pfam13417 272560006052 C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205 272560006053 dimer interface [polypeptide binding]; other site 272560006054 N-terminal domain interface [polypeptide binding]; other site 272560006055 putative substrate binding pocket (H-site) [chemical binding]; other site 272560006056 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 29.9, E-value 3.8e-06 272560006057 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 32.4, E-value 6.9e-07 272560006058 proline/glycine betaine transporter; Provisional; Region: PRK10642 272560006059 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560006060 putative substrate translocation pore; other site 272560006061 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 205.4, E-value 5.8e-59 272560006062 11 probable transmembrane helices predicted for BPSL1339 by TMHMM2.0 at aa 76-98, 110-127, 142-164, 177-199, 209-228, 267-289, 304-326, 333-355, 365-387, 394-416 and 426-445 272560006063 PS00216 Sugar transport proteins signature 1. 272560006064 PS00217 Sugar transport proteins signature 2. 272560006065 hypothetical protein; Provisional; Region: PRK02237 272560006066 Pfam match to entry PF02694 UPF0060, Uncharacterized BCR, YnfA/UPF0060 family , score 151.6, E-value 8.9e-43 272560006067 4 probable transmembrane helices predicted for BPSL1340 by TMHMM2.0 at aa 7-29, 34-56, 63-81 and 91-108 272560006068 DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406 272560006069 DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131 272560006070 active site 272560006071 catalytic site [active] 272560006072 substrate binding site [chemical binding]; other site 272560006073 Pfam match to entry PF00929 Exonuclease, Exonuclease , score 132.7, E-value 4.4e-37 272560006074 RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278 272560006075 RNA/DNA hybrid binding site [nucleotide binding]; other site 272560006076 active site 272560006077 Pfam match to entry PF00075 rnaseH, RNase H , score 206.3, E-value 3.1e-59 272560006078 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226 272560006079 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560006080 hydroxyacylglutathione hydrolase; Region: GSH_gloB; TIGR03413 272560006081 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 153.4, E-value 2.6e-43 272560006082 Signal peptide predicted for BPSL1345 by SignalP 2.0 HMM (Signal peptide probabilty 0.976) with cleavage site probability 0.542 between residues 40 and 41; signal peptide 272560006083 membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783 272560006084 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560006085 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560006086 catalytic residue [active] 272560006087 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560006088 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560006089 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain , score 99.8, E-value 3.5e-27 272560006090 PS00922 Prokaryotic transglycosylases signature. 272560006091 Pfam match to entry PF01476 LysM, LysM domain , score 26.1, E-value 5.2e-05 272560006092 Pfam match to entry PF01476 LysM, LysM domain , score 28.2, E-value 1.3e-05 272560006093 Predicted helix-turn-helix motif with score 1312.000, SD 3.66 at aa 442-463, sequence QSMEALASRYGVSVAQLRGWNR 272560006094 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560006095 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560006096 putative substrate translocation pore; other site 272560006097 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -77.5, E-value 4.2e-05 272560006098 12 probable transmembrane helices predicted for BPSL1346 by TMHMM2.0 at aa 29-51, 66-88, 95-112, 116-138, 150-169, 179-201, 231-253, 268-290, 297-319, 329-351, 363-385 and 400-417 272560006099 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 272560006100 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560006101 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560006102 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 5.4, E-value 0.45 272560006103 Predicted helix-turn-helix motif with score 1520.000, SD 4.36 at aa 256-277, sequence PTMDVLAAELGVSPRTLRRRLA 272560006104 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 49.9, E-value 3.7e-12 272560006105 carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564 272560006106 Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097 272560006107 Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744 272560006108 catalytic site [active] 272560006109 subunit interface [polypeptide binding]; other site 272560006110 Pfam match to entry PF00988 CPSase_sm_chain, Carbamoyl-phosphate synthase small chain, CPSase domain , score 295.5, E-value 4.4e-86 272560006111 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 233.9, E-value 1.5e-67 272560006112 PS00442 Glutamine amidotransferases class-I active site. 272560006113 leucine export protein LeuE; Provisional; Region: PRK10958 272560006114 6 probable transmembrane helices predicted for BPSL1350 by TMHMM2.0 at aa 13-35, 48-70, 74-96, 127-149, 160-182 and 195-217 272560006115 Pfam match to entry PF01810 LysE, LysE type translocator , score 136.5, E-value 3.1e-38 272560006116 carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294 272560006117 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560006118 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 272560006119 Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096 272560006120 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560006121 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560006122 Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424 272560006123 IMP binding site; other site 272560006124 dimer interface [polypeptide binding]; other site 272560006125 interdomain contacts; other site 272560006126 partial ornithine binding site; other site 272560006127 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 208.5, E-value 6.8e-60 272560006128 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006129 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 408.4, E-value 4.5e-120 272560006130 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560006131 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560006132 Pfam match to entry PF02787 CPSase_L_D3, Carbamoyl-phosphate synthetase large chain, oligomerisation domain , score 212.9, E-value 3.1e-61 272560006133 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 91.0, E-value 1.5e-24 272560006134 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 71.9, E-value 8.7e-19 272560006135 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560006136 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560006137 Pfam match to entry PF02142 MGS, MGS-like domain , score 116.1, E-value 4.4e-32 272560006138 transcription elongation factor GreA; Reviewed; Region: greA; PRK00226 272560006139 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 272560006140 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 272560006141 Pfam match to entry PF03449 GreA_GreB_N, Prokaryotic transcription elongation factor, GreA/GreB, N-terminal domain , score 140.6, E-value 1.8e-39 272560006142 PS00829 Prokaryotic transcription elongation factors signature 1. 272560006143 Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain , score 112.1, E-value 6.9e-31 272560006144 PS00830 Prokaryotic transcription elongation factors signature 2. 272560006145 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006146 Domain of unknown function (DUF4149); Region: DUF4149; pfam13664 272560006147 4 probable transmembrane helices predicted for BPSL1353 by TMHMM2.0 at aa 5-22, 37-59, 72-94 and 114-136 272560006148 Escherichia coli YhbY is associated with pre-50S ribosomal subunits, which implies a function in ribosome assembly; Region: CRS1_YhbY; smart01103 272560006149 23S rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: FtsJ; COG0293 272560006150 Pfam match to entry PF01728 FtsJ, FtsJ-like methyltransferase , score 199.7, E-value 3e-57 272560006151 ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465 272560006152 FtsH Extracellular; Region: FtsH_ext; pfam06480 272560006153 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006154 Walker A motif; other site 272560006155 ATP binding site [chemical binding]; other site 272560006156 Walker B motif; other site 272560006157 arginine finger; other site 272560006158 Peptidase family M41; Region: Peptidase_M41; pfam01434 272560006159 2 probable transmembrane helices predicted for BPSL1356 by TMHMM2.0 at aa 5-23 and 100-122 272560006160 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006161 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 335.1, E-value 5e-98 272560006162 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006163 PS00674 AAA-protein family signature. 272560006164 Pfam match to entry PF01434 Peptidase_M41, Peptidase M41 , score 360.7, E-value 1e-105 272560006165 Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294 272560006166 DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739 272560006167 substrate binding pocket [chemical binding]; other site 272560006168 dimer interface [polypeptide binding]; other site 272560006169 inhibitor binding site; inhibition site 272560006170 PS00792 Dihydropteroate synthase signature 1. 272560006171 Pfam match to entry PF00809 Pterin_bind, Pterin binding enzyme , score 354.9, E-value 5.7e-104 272560006172 PS00793 Dihydropteroate synthase signature 2. 272560006173 phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887 272560006174 GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802 272560006175 active site 272560006176 substrate binding site [chemical binding]; other site 272560006177 metal binding site [ion binding]; metal-binding site 272560006178 Pfam match to entry PF02878 PGM_PMM_I, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I , score 195.0, E-value 7.7e-56 272560006179 PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 272560006180 Pfam match to entry PF02879 PGM_PMM_II, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II , score 132.2, E-value 6.2e-37 272560006181 Pfam match to entry PF02880 PGM_PMM_III, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III , score 81.8, E-value 9e-22 272560006182 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006183 Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase, C-terminal domain , score 33.8, E-value 2.6e-07 272560006184 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560006185 Signal peptide predicted for BPSL1359 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 22 and 23; signal peptide 272560006186 Pfam match to entry PF01449 PstS, Phosphate-binding protein , score 452.3, E-value 2.6e-133 272560006187 ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573 272560006188 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560006189 dimer interface [polypeptide binding]; other site 272560006190 conserved gate region; other site 272560006191 putative PBP binding loops; other site 272560006192 ABC-ATPase subunit interface; other site 272560006193 6 probable transmembrane helices predicted for BPSL1360 by TMHMM2.0 at aa 36-58, 87-109, 121-143, 175-197, 236-258 and 297-319 272560006194 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 36.3, E-value 4.7e-08 272560006195 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560006196 phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268 272560006197 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560006198 dimer interface [polypeptide binding]; other site 272560006199 conserved gate region; other site 272560006200 putative PBP binding loops; other site 272560006201 ABC-ATPase subunit interface; other site 272560006202 6 probable transmembrane helices predicted for BPSL1361 by TMHMM2.0 at aa 25-47, 85-107, 120-142, 147-166, 198-220 and 261-283 272560006203 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 57.2, E-value 2.4e-14 272560006204 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560006205 phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744 272560006206 ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260 272560006207 Walker A/P-loop; other site 272560006208 ATP binding site [chemical binding]; other site 272560006209 Q-loop/lid; other site 272560006210 ABC transporter signature motif; other site 272560006211 Walker B; other site 272560006212 D-loop; other site 272560006213 H-loop/switch region; other site 272560006214 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 237.9, E-value 9.6e-69 272560006215 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006216 PS00211 ABC transporters family signature. 272560006217 phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135 272560006218 PhoU domain; Region: PhoU; pfam01895 272560006219 PhoU domain; Region: PhoU; pfam01895 272560006220 Pfam match to entry PF01895 PhoU, PhoU family , score 104.7, E-value 1.2e-28 272560006221 Pfam match to entry PF01895 PhoU, PhoU family , score 86.0, E-value 5.1e-23 272560006222 phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154 272560006223 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560006224 active site 272560006225 phosphorylation site [posttranslational modification] 272560006226 intermolecular recognition site; other site 272560006227 dimerization interface [polypeptide binding]; other site 272560006228 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560006229 DNA binding site [nucleotide binding] 272560006230 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 105.6, E-value 6.1e-29 272560006231 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 109.7, E-value 3.7e-30 272560006232 Signal peptide predicted for BPSL1365 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.693 between residues 38 and 39; signal peptide 272560006233 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 272560006234 PAS domain; Region: PAS; smart00091 272560006235 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560006236 dimer interface [polypeptide binding]; other site 272560006237 phosphorylation site [posttranslational modification] 272560006238 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560006239 ATP binding site [chemical binding]; other site 272560006240 Mg2+ binding site [ion binding]; other site 272560006241 G-X-G motif; other site 272560006242 Pfam match to entry PF00989 PAS, PAS domain , score 17.9, E-value 0.00016 272560006243 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 93.6, E-value 2.5e-25 272560006244 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 152.1, E-value 6.3e-43 272560006245 polyphosphate kinase; Provisional; Region: PRK05443 272560006246 Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089 272560006247 Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503 272560006248 Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165 272560006249 putative domain interface [polypeptide binding]; other site 272560006250 putative active site [active] 272560006251 catalytic site [active] 272560006252 Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168 272560006253 putative domain interface [polypeptide binding]; other site 272560006254 putative active site [active] 272560006255 catalytic site [active] 272560006256 Pfam match to entry PF02503 PP_kinase, Polyphosphate kinase , score 1129.9, E-value 0 272560006257 Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248 272560006258 exopolyphosphatase; Region: exo_poly_only; TIGR03706 272560006259 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 272560006260 nucleotide binding site [chemical binding]; other site 272560006261 Pfam match to entry PF02541 Ppx-GppA, Ppx/GppA phosphatase , score 245.8, E-value 3.9e-71 272560006262 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 272560006263 active site 272560006264 8 probable transmembrane helices predicted for BPSL1369 by TMHMM2.0 at aa 25-47, 52-74, 95-117, 154-176, 185-207, 241-263, 268-287 and 291-313 272560006265 Pfam match to entry PF01569 PAP2, PAP2 superfamily , score 6.0, E-value 0.00075 272560006266 Probable gene remnant. Similar to the N-terminal region of Bordetella bronchiseptica phage-related integrase SWALL:Q7WFY2 (EMBL:BX640449) (424 aa) fasta scores: E(): 0.68, 25.64% id in 78 aa, and Xanthomonas axonopodis pv. citri str. 306 phage-related integrase Int SWALL:Q8PKF1 (EMBL:AE011860) (399 aa) fasta scores: E(): 0.76, 29.11% id in 79 aa; phage-related integrase (fragment) 272560006267 Probable gene remnant. Similar to the C-terminal regions of Burkholderia thailandensis GP33 SWALL:Q8VP93 (EMBL:AY063741) (223 aa) fasta scores: E(): 1.5e-22, 84.41% id in 77 aa, and Chromobacterium violaceum hypothetical protein SWALL:Q7NVB7 (EMBL:AE016918) (214 aa) fasta scores: E(): 4.6e-07, 42.66% id in 75 aa. CDS contains a frameshift after codon 32;conserved hypothetical protein (fragment) 272560006268 2 probable transmembrane helices predicted for BPSL1372 by TMHMM2.0 at aa 7-24 and 58-77 272560006269 Protein of unknown function (DUF2778); Region: DUF2778; pfam10908 272560006270 Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040 272560006271 catalytic core [active] 272560006272 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score -77.9, E-value 4.6e-05 272560006273 Acetyltransferase (GNAT) domain; Region: Acetyltransf_5; cl17496 272560006274 1 probable transmembrane helix predicted for BPSL1376 by TMHMM2.0 at aa 37-56 272560006275 NlpB/DapX lipoprotein; Region: Lipoprotein_18; cl19507 272560006276 Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139 272560006277 Signal peptide predicted for BPSL1377 by SignalP 2.0 HMM (Signal peptide probabilty 0.963) with cleavage site probability 0.546 between residues 18 and 19; signal peptide 272560006278 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006279 DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136 272560006280 DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367 272560006281 11 probable transmembrane helices predicted for BPSL1378 by TMHMM2.0 at aa 26-43, 58-80, 109-131, 146-168, 173-195, 205-227, 256-274, 294-316, 329-351, 371-393 and 406-428 272560006282 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 45.1, E-value 1e-10 272560006283 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 99.6, E-value 4e-27 272560006284 Protein of unknown function (DUF2288); Region: DUF2288; pfam10052 272560006285 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 272560006286 Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS); Region: MACS_like_3; cd05971 272560006287 active site 272560006288 acyl-activating enzyme (AAE) consensus motif; other site 272560006289 putative CoA binding site [chemical binding]; other site 272560006290 AMP binding site [chemical binding]; other site 272560006291 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 380.6, E-value 1.1e-111 272560006292 PS00455 AMP-binding domain signature. 272560006293 Signal peptide predicted for BPSL1381 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.624 between residues 30 and 31; signal peptide 272560006294 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560006295 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 272560006296 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560006297 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 128.3, E-value 9.1e-36 272560006298 Pfam match to entry PF01476 LysM, LysM domain , score 60.7, E-value 2.1e-15 272560006299 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006300 aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648 272560006301 active site 272560006302 catalytic residues [active] 272560006303 Pfam match to entry PF01263 Aldose_epim, Aldose 1-epimerase , score 20.0, E-value 2.3e-07 272560006304 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK12554 272560006305 7 probable transmembrane helices predicted for BPSL1383 by TMHMM2.0 at aa 5-27, 42-64, 89-108, 118-135, 193-210, 220-242 and 249-271 272560006306 Pfam match to entry PF02673 BacA, Bacitracin resistance protein BacA , score 81.9, E-value 8.3e-22 272560006307 Genomic island GI 7; possible prophage remnant 272560006308 Partial CDS. Similar to the C-terminal region of Escherichia coli prophage dlp12 integrase IntD or Int or b0537 SWALL:INTD_ECOLI (SWALL:P24218) (387 aa) fasta scores: E(): 5.3e-15, 50% id in 94 aa, and of Bacteriophage P22 Integrase Int SWALL:VINT_BPP22 (SWALL:P04890) (387 aa) fasta scores: E(): 4.8e-13, 46.31% id in 95 aa; phage-related protein (fragment) 272560006309 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -27.8, E-value 0.021 272560006310 Probable gene remnant. C-terminal region is similar to the C-terminus of Burkholderia thailandensis temperate bacteriophage protein Gp27 SWALL:Q8VP99 (EMBL:AY063741) (146 aa) fasta scores: E(): 6.9e-14, 86.66% id in 45 aa, and to bacteriophage phiE125 protein Gp27 SWALL:Q8W6S4 (EMBL:AF447491) (262 aa) fasta scores: E(): 1.1e-13, 86.66% id in 45 aa; phage-related protein (fragment) 272560006311 Immunity protein 32; Region: Imm32; pfam15579 272560006312 Restriction endonuclease fold toxin 5; Region: Tox-REase-5; pfam15648 272560006313 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 272560006314 Partial CDS. Similar to the N-terminal region of Bacteriophage phiE125 gp29 SWALL:Q8W6S2 (EMBL:AF447491) (186 aa) fasta scores: E(): 6.5e-11, 41.73% id in 115 aa, and N-terminal region similar to Pseudomonas aeruginosa hypothetical protein pa1508 SWALL:Q9I3K4 (EMBL:AE004579) (86 aa) fasta scores: E(): 7.2e-09, 50% id in 88 aa; phage related protein (fragment) 272560006315 Partial CDS. Similar to the C-terminal region of Bacteriophage phiE125 gp27 SWALL:Q8W6S4 (EMBL:AF447491) (262 aa) fasta scores: E(): 2.3e-17, 75.75% id in 66 aa; phage related protein (fragment) 272560006316 Immunity protein 32; Region: Imm32; pfam15579 272560006317 Signal peptide predicted for BPSL1393 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 35 and 36; signal peptide 272560006318 Avidin family; Region: Avidin; pfam01382 272560006319 Pfam match to entry PF01382 Avidin, Avidin family , score 35.4, E-value 8.3e-08 272560006320 Signal peptide predicted for BPSL1394 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 between residues 25 and 26; signal peptide 272560006321 Catalytic domain of EDTA-resistant nuclease Nuc from Salmonella typhimurium and similar proteins; Region: PLDc_Nuc; cd09170 272560006322 PLD-like domain; Region: PLDc_2; pfam13091 272560006323 putative active site [active] 272560006324 catalytic site [active] 272560006325 Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_1; cd09996 272560006326 active site 272560006327 Zn binding site [ion binding]; other site 272560006328 Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase , score 271.6, E-value 6.8e-79 272560006329 12 probable transmembrane helices predicted for BPSL1396 by TMHMM2.0 at aa 28-50, 65-87, 94-116, 121-143, 150-169, 179-201, 221-243, 258-280, 287-304, 314-336, 343-365 and 370-392 272560006330 PS00044 Bacterial regulatory proteins, lysR family signature. 272560006331 Signal peptide predicted for BPSL1397 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 32 and 33; signal peptide 272560006332 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560006333 trimer interface [polypeptide binding]; other site 272560006334 eyelet of channel; other site 272560006335 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -99.7, E-value 0.026 272560006336 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560006337 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560006338 DNA binding residues [nucleotide binding] 272560006339 dimerization interface [polypeptide binding]; other site 272560006340 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 35.5, E-value 7.8e-08 272560006341 Predicted helix-turn-helix motif with score 1800.000, SD 5.32 at aa 325-346, sequence RSHKEVAQQMEIAPATVRHYLR 272560006342 2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522 272560006343 Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558 272560006344 Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546 272560006345 Pfam match to entry PF02558 ApbA, Ketopantoate reductase PanE/ApbA , score 47.0, E-value 2.8e-11 272560006346 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560006347 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560006348 Pfam match to entry PF01047 MarR, MarR family , score 86.6, E-value 3.2e-23 272560006349 Predicted helix-turn-helix motif with score 1229.000, SD 3.37 at aa 78-99, sequence FSIMELARRANLDKSQASRAAE 272560006350 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 272560006351 Pfam match to entry PF02595 DUF168, Uncharacterized BCR, COG1929 , score 252.0, E-value 5.3e-73 272560006352 trigger factor; Provisional; Region: tig; PRK01490 272560006353 Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697 272560006354 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 272560006355 Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698 272560006356 Pfam match to entry PF00254 FKBP, FKBP-type peptidyl-prolyl cis-trans isomerase , score 30.6, E-value 2.4e-06 272560006357 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006358 Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017 272560006359 oligomer interface [polypeptide binding]; other site 272560006360 active site residues [active] 272560006361 Pfam match to entry PF00574 CLP_protease, Clp protease , score 421.8, E-value 4.2e-124 272560006362 PS00381 Endopeptidase Clp serine active site. 272560006363 PS00382 Endopeptidase Clp histidine active site. 272560006364 ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342 272560006365 ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689 272560006366 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006367 Walker A motif; other site 272560006368 ATP binding site [chemical binding]; other site 272560006369 Walker B motif; other site 272560006370 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 272560006371 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 91.4, E-value 1.2e-24 272560006372 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006373 ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466 272560006374 ATP-dependent protease La (LON) domain; Region: LON; pfam02190 272560006375 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 272560006376 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006377 Walker A motif; other site 272560006378 ATP binding site [chemical binding]; other site 272560006379 Walker B motif; other site 272560006380 arginine finger; other site 272560006381 Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362 272560006382 Pfam match to entry PF02190 LON, ATP-dependent protease La (LON) domain , score 157.7, E-value 1.3e-44 272560006383 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 161.4, E-value 1e-45 272560006384 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006385 PS01046 ATP-dependent serine proteases, lon family, serine active site. 272560006386 RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY, is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552 272560006387 30S subunit binding site; other site 272560006388 Partial CDS. Similar to the N-terminal region of Bacillus subtilis ydaT protein YdaT SWALL:P96595 (EMBL:AB001488) (150 aa) fasta scores: E(): 0.017, 46.8% id in 47 aa;conserved hypothetical protein (fragment) 272560006389 periplasmic folding chaperone; Provisional; Region: PRK10788 272560006390 SurA N-terminal domain; Region: SurA_N_3; cl07813 272560006391 Signal peptide predicted for BPSL1410 by SignalP 2.0 HMM (Signal peptide probabilty 0.607) with cleavage site probability 0.330 between residues 44 and 45; signal peptide 272560006392 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560006393 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain , score 100.4, E-value 2.3e-27 272560006394 Signal peptide predicted for BPSL1411 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.951 between residues 25 and 26; signal peptide 272560006395 Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822 272560006396 active site 272560006397 catalytic triad [active] 272560006398 oxyanion hole [active] 272560006399 switch loop; other site 272560006400 Pfam match to entry PF00657 Lipase_GDSL, Lipase/Acylhydrolase with GDSL-like motif , score 44.4, E-value 1.6e-10 272560006401 Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181 272560006402 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 272560006403 Walker A/P-loop; other site 272560006404 ATP binding site [chemical binding]; other site 272560006405 Q-loop/lid; other site 272560006406 ABC transporter signature motif; other site 272560006407 Walker B; other site 272560006408 D-loop; other site 272560006409 H-loop/switch region; other site 272560006410 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 201.4, E-value 8.8e-58 272560006411 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006412 PS00211 ABC transporters family signature. 272560006413 glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179 272560006414 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015 272560006415 active site 272560006416 dimer interface [polypeptide binding]; other site 272560006417 Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016 272560006418 dimer interface [polypeptide binding]; other site 272560006419 active site 272560006420 Pfam match to entry PF00342 PGI, Phosphoglucose isomerase , score 795.5, E-value 1.3e-236 272560006421 PS00765 Phosphoglucose isomerase signature 1. 272560006422 Uncharacterized conserved protein [Function unknown]; Region: COG0062 272560006423 B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171 272560006424 putative substrate binding site [chemical binding]; other site 272560006425 putative ATP binding site [chemical binding]; other site 272560006426 Pfam match to entry PF01256 UPF0031, Uncharacterized protein family UPF0031 , score 181.5, E-value 9.2e-52 272560006427 Pfam match to entry PF03853 YjeF_N, YjeF-related protein N-terminus , score 126.1, E-value 4.2e-35 272560006428 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 272560006429 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560006430 phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297 272560006431 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203 272560006432 dimerization interface [polypeptide binding]; other site 272560006433 ATP binding site [chemical binding]; other site 272560006434 PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204 272560006435 dimerization interface [polypeptide binding]; other site 272560006436 ATP binding site [chemical binding]; other site 272560006437 Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740 272560006438 putative active site [active] 272560006439 catalytic triad [active] 272560006440 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain , score 65.3, E-value 8.2e-17 272560006441 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain , score 125.3, E-value 7.1e-35 272560006442 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain , score 79.7, E-value 3.8e-21 272560006443 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 272560006444 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560006445 Coenzyme A binding pocket [chemical binding]; other site 272560006446 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 44.1, E-value 2e-10 272560006447 Signal peptide predicted for BPSL1418 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 22 and 23; signal peptide 272560006448 SurA N-terminal domain; Region: SurA_N_3; cl07813 272560006449 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560006450 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain , score 137.3, E-value 1.8e-38 272560006451 BolA-like protein; Region: BolA; pfam01722 272560006452 Pfam match to entry PF01722 BolA, BolA-like protein , score 92.6, E-value 5.1e-25 272560006453 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006454 intracellular septation protein A; Reviewed; Region: PRK00259 272560006455 6 probable transmembrane helices predicted for BPSL1420 by TMHMM2.0 at aa 27-49, 53-75, 82-101, 111-129, 151-173 and 183-202 272560006456 methionine sulfoxide reductase B; Provisional; Region: PRK00222 272560006457 Pfam match to entry PF01641 SelR, SelR domain , score 282.3, E-value 4.1e-82 272560006458 hypothetical protein; Validated; Region: PRK00029 272560006459 Pfam match to entry PF02696 UPF0061, Uncharacterized ACR, YdiU/UPF0061 family , score 383.4, E-value 1.5e-112 272560006460 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07008 272560006461 Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles; Region: ttLC_FACS_AlkK_like; cd12119 272560006462 dimer interface [polypeptide binding]; other site 272560006463 acyl-activating enzyme (AAE) consensus motif; other site 272560006464 putative active site [active] 272560006465 AMP binding site [chemical binding]; other site 272560006466 putative CoA binding site [chemical binding]; other site 272560006467 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 319.0, E-value 3.7e-93 272560006468 PS00455 AMP-binding domain signature. 272560006469 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006470 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560006471 multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154 272560006472 substrate binding site [chemical binding]; other site 272560006473 oxyanion hole (OAH) forming residues; other site 272560006474 trimer interface [polypeptide binding]; other site 272560006475 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560006476 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560006477 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560006478 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 177.7, E-value 1.2e-50 272560006479 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 271.0, E-value 1e-78 272560006480 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 134.6, E-value 1.2e-37 272560006481 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 2.1, E-value 0.00031 272560006482 Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011 272560006483 catalytic triad [active] 272560006484 metal binding site [ion binding]; metal-binding site 272560006485 conserved cis-peptide bond; other site 272560006486 Pfam match to entry PF00857 Isochorismatase, Isochorismatase , score 76.1, E-value 4.8e-20 272560006487 acetyl-CoA acetyltransferase; Provisional; Region: PRK07108 272560006488 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560006489 dimer interface [polypeptide binding]; other site 272560006490 active site 272560006491 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 266.5, E-value 2.3e-77 272560006492 PS00098 Thiolases acyl-enzyme intermediate signature. 272560006493 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560006494 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 213.5, E-value 2.1e-61 272560006495 PS00737 Thiolases signature 2. 272560006496 Stress responsive A/B Barrel Domain; Region: Dabb; smart00886 272560006497 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560006498 CoenzymeA binding site [chemical binding]; other site 272560006499 subunit interaction site [polypeptide binding]; other site 272560006500 PHB binding site; other site 272560006501 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 48.7, E-value 8.3e-12 272560006502 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 272560006503 Prostaglandin dehydrogenases; Region: PGDH; cd05288 272560006504 NAD(P) binding site [chemical binding]; other site 272560006505 substrate binding site [chemical binding]; other site 272560006506 dimer interface [polypeptide binding]; other site 272560006507 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 139.7, E-value 3.5e-39 272560006508 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560006509 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560006510 Pfam match to entry PF00135 COesterase, Carboxylesterase , score 14.1, E-value 0.00016 272560006511 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 272560006512 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560006513 Coenzyme A binding pocket [chemical binding]; other site 272560006514 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 44.2, E-value 2e-10 272560006515 NRDE protein; Region: NRDE; cl01315 272560006516 Predicted aminomethyltransferase related to GcvT [General function prediction only]; Region: COG0354 272560006517 Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571 272560006518 folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317 272560006519 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 272560006520 Signal peptide predicted for BPSL1435 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.602 between residues 37 and 38; signal peptide 272560006521 proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010 272560006522 dimerization interface [polypeptide binding]; other site 272560006523 Pfam match to entry PF02618 DUF175, Uncharacterized BCR, YceG family COG1559 , score 290.0, E-value 2e-84 272560006524 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006525 PS00904 Protein prenyltransferases alpha subunit repeat signature. 272560006526 thymidylate kinase; Validated; Region: tmk; PRK00698 272560006527 Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672 272560006528 TMP-binding site; other site 272560006529 ATP-binding site [chemical binding]; other site 272560006530 Pfam match to entry PF02223 Thymidylate_kin, Thymidylate kinase , score 168.0, E-value 1e-47 272560006531 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006532 DNA polymerase III subunit delta'; Validated; Region: PRK06964 272560006533 DNA polymerase III subunit delta'; Validated; Region: PRK08485 272560006534 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560006535 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560006536 Coenzyme A binding pocket [chemical binding]; other site 272560006537 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 73.2, E-value 3.5e-19 272560006538 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 272560006539 active site 272560006540 PS01137 Uncharacterized protein family UPF0006 signature 1. 272560006541 Pfam match to entry PF01026 TatD_DNase, TatD related DNase , score 273.8, E-value 1.5e-79 272560006542 PS01091 Uncharacterized protein family UPF0006 signature 3. 272560006543 Signal peptide predicted for BPSL1440 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.995 between residues 38 and 39; signal peptide 272560006544 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 272560006545 ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204 272560006546 Ankyrin repeats (3 copies); Region: Ank_2; pfam12796 272560006547 Pfam match to entry PF00023 ank, Ankyrin repeat , score 1.6, E-value 12 272560006548 Pfam match to entry PF00023 ank, Ankyrin repeat , score 11.8, E-value 0.59 272560006549 Pfam match to entry PF00023 ank, Ankyrin repeat , score 34.4, E-value 1.7e-07 272560006550 Pfam match to entry PF00023 ank, Ankyrin repeat , score 37.5, E-value 2e-08 272560006551 Signal peptide predicted for BPSL1441 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.433 between residues 20 and 21; signal peptide 272560006552 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668 272560006553 Mechanosensitive ion channel; Region: MS_channel; pfam00924 272560006554 4 probable transmembrane helices predicted for BPSL1442 by TMHMM2.0 at aa 15-37, 50-72, 87-109 and 140-162 272560006555 Pfam match to entry PF00924 MS_channel, Mechanosensitive ion channel , score 49.0, E-value 6.9e-12 272560006556 Predicted ATPase [General function prediction only]; Region: COG4637 272560006557 AAA domain; Region: AAA_23; pfam13476 272560006558 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560006559 Walker A/P-loop; other site 272560006560 ATP binding site [chemical binding]; other site 272560006561 AAA domain; Region: AAA_21; pfam13304 272560006562 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain , score 17.4, E-value 3.8e-05 272560006563 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006564 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 272560006565 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560006566 putative ADP-binding pocket [chemical binding]; other site 272560006567 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 88.7, E-value 7.7e-24 272560006568 Signal peptide predicted for BPSL1445 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.603 between residues 34 and 35; signal peptide 272560006569 The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524 272560006570 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006571 Domain of unknown function DUF221; Region: DUF221; pfam02714 272560006572 2 probable transmembrane helices predicted for BPSL1446 by TMHMM2.0 at aa 20-42 and 120-142 272560006573 hypothetical protein; Provisional; Region: PRK11505 272560006574 Signal peptide predicted for BPSL1447 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 22 and 23; signal peptide 272560006575 psiF repeat; Region: PsiF_repeat; pfam07769 272560006576 psiF repeat; Region: PsiF_repeat; pfam07769 272560006577 Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964 272560006578 active site 272560006579 homotetramer interface [polypeptide binding]; other site 272560006580 homodimer interface [polypeptide binding]; other site 272560006581 PS00144 Asparaginase / glutaminase active site signature 1. 272560006582 Pfam match to entry PF00710 Asparaginase, Asparaginase , score 436.7, E-value 1.3e-128 272560006583 PS00917 Asparaginase / glutaminase active site signature 2. 272560006584 LysM domain/BON superfamily protein; Provisional; Region: PRK11198 272560006585 BON domain; Region: BON; pfam04972 272560006586 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560006587 Pfam match to entry PF01476 LysM, LysM domain , score 55.5, E-value 7.4e-14 272560006588 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006589 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560006590 tartronate semialdehyde reductase; Provisional; Region: PRK15059 272560006591 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560006592 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score -46.3, E-value 3.2e-06 272560006593 Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622 272560006594 hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234 272560006595 glyoxylate carboligase; Provisional; Region: PRK11269 272560006596 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560006597 PYR/PP interface [polypeptide binding]; other site 272560006598 dimer interface [polypeptide binding]; other site 272560006599 TPP binding site [chemical binding]; other site 272560006600 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560006601 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 272560006602 TPP-binding site [chemical binding]; other site 272560006603 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 115.0, E-value 9e-32 272560006604 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 118.8, E-value 6.7e-33 272560006605 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 201.1, E-value 1.1e-57 272560006606 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560006607 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560006608 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560006609 putative effector binding pocket; other site 272560006610 dimerization interface [polypeptide binding]; other site 272560006611 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 52.4, E-value 6.4e-13 272560006612 Predicted helix-turn-helix motif with score 1009.000, SD 2.62 at aa 17-38, sequence GSLAAAALEEGVSPVVLGRRID 272560006613 PS00044 Bacterial regulatory proteins, lysR family signature. 272560006614 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 161.4, E-value 9.8e-46 272560006615 Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116 272560006616 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560006617 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 272560006618 active site 272560006619 metal binding site [ion binding]; metal-binding site 272560006620 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 48.8, E-value 7.9e-12 272560006621 RNA polymerase sigma factor; Provisional; Region: PRK12533 272560006622 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560006623 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560006624 DNA binding residues [nucleotide binding] 272560006625 PS01063 Sigma-70 factors ECF subfamily signature. 272560006626 Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 166-187, sequence MSYREIAAIADLPVGTVMSRLA 272560006627 Putative zinc-finger; Region: zf-HC2; pfam13490 272560006628 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 272560006629 30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453 272560006630 Pfam match to entry PF01250 Ribosomal_S6, Ribosomal protein S6 , score 152.1, E-value 6.4e-43 272560006631 Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930 272560006632 30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391 272560006633 Pfam match to entry PF01084 Ribosomal_S18, Ribosomal protein S18 , score 103.4, E-value 2.9e-28 272560006634 50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137 272560006635 Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281 272560006636 Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948 272560006637 Pfam match to entry PF01281 Ribosomal_L9_N, Ribosomal protein L9, N-terminal domain , score 94.2, E-value 1.7e-25 272560006638 PS00651 Ribosomal protein L9 signature. 272560006639 Pfam match to entry PF03948 Ribosomal_L9_C, Ribosomal protein L9, C-terminal domain , score 91.0, E-value 1.6e-24 272560006640 replicative DNA helicase; Provisional; Region: PRK07004 272560006641 DnaB-like helicase N terminal domain; Region: DnaB; pfam00772 272560006642 DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984 272560006643 Walker A motif; other site 272560006644 ATP binding site [chemical binding]; other site 272560006645 Walker B motif; other site 272560006646 DNA binding loops [nucleotide binding] 272560006647 Pfam match to entry PF00772 DnaB, DnaB-like helicase N terminal domain , score 160.8, E-value 1.6e-45 272560006648 Pfam match to entry PF03796 DnaB_C, DnaB-like helicase C terminal domain , score 432.6, E-value 2.3e-127 272560006649 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006650 Predicted helix-turn-helix motif with score 1297.000, SD 3.60 at aa 354-375, sequence RSLKSLAKELDVPVIALSQLNR 272560006651 Phosphate transport regulator (distant homolog of PhoU) [Inorganic ion transport and metabolism]; Region: COG1392 272560006652 TIGR00153 family protein; Region: TIGR00153 272560006653 Pfam match to entry PF01865 DUF47, Protein of unknown function DUF47 , score 65.6, E-value 6.8e-17 272560006654 Phosphate transporter family; Region: PHO4; pfam01384 272560006655 8 probable transmembrane helices predicted for BPSL1464 by TMHMM2.0 at aa 7-26, 46-63, 83-105, 143-165, 200-217, 222-244, 257-279 and 310-332 272560006656 Pfam match to entry PF01384 PHO4, Phosphate transporter family , score 325.0, E-value 5.6e-95 272560006657 outer membrane lipoprotein; Provisional; Region: spr; PRK10838 272560006658 Signal peptide predicted for BPSL1465 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.542 between residues 32 and 33; signal peptide 272560006659 NlpC/P60 family; Region: NLPC_P60; pfam00877 272560006660 Pfam match to entry PF00877 NLPC_P60, NLP/P60 family , score 159.6, E-value 3.5e-45 272560006661 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006662 NYN ribonuclease and ATPase of PhoH family domains [General function prediction only]; Region: COG1875 272560006663 PIN domain of bacterial Smg6-like homologs with PhoH-like ATPase domains; Region: PIN_PhoHL-ATPase; cd09883 272560006664 putative active site [active] 272560006665 PhoH-like protein; Region: PhoH; pfam02562 272560006666 Pfam match to entry PF02562 PhoH, PhoH-like protein , score -32.8, E-value 9.7e-13 272560006667 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006668 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 272560006669 Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017 272560006670 catalytic triad [active] 272560006671 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 132.5, E-value 5.2e-37 272560006672 Predicted helix-turn-helix motif with score 1131.000, SD 3.04 at aa 57-78, sequence KFKKAGAEIVGVSRDSLRSHEN 272560006673 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394 272560006674 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 272560006675 Similar to Salmonella typhimurium hypothetical protein YfbG or stm2299 SWALL:YFBG_SALTY (SWALL:O52325) (660 aa) fasta scores: E(): 3.5e-115, 48.5% id in 668 aa, and to Escherichia coli hypothetical protein YfbG or b2255 SWALL:YFBG_ECOLI (SWALL:P77398) (660 aa) fasta scores: E(): 1.2e-112, 46.31% id in 665 aa. CDS contains a frameshift after codon 315;conserved hypothetical protein (pseudogene) 272560006676 Pfam match to entry PF02911 formyl_trans_C, Formyl transferase, C-terminal domain , score 60.8, E-value 1.9e-15 272560006677 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 65.3, E-value 8.7e-17 272560006678 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 272560006679 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 272560006680 Ligand binding site; other site 272560006681 Putative Catalytic site; other site 272560006682 DXD motif; other site 272560006683 2 probable transmembrane helices predicted for BPSL1471 by TMHMM2.0 at aa 237-259 and 271-293 272560006684 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 104.1, E-value 1.8e-28 272560006685 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 272560006686 inhibitor-cofactor binding pocket; inhibition site 272560006687 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560006688 catalytic residue [active] 272560006689 Pfam match to entry PF01041 DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase , score 472.1, E-value 2.9e-139 272560006690 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971 272560006691 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 10.8, E-value 0.015 272560006692 4 probable transmembrane helices predicted for BPSL1473 by TMHMM2.0 at aa 5-27, 47-69, 76-98 and 102-121 272560006693 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 272560006694 Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158 272560006695 11 probable transmembrane helices predicted for BPSL1474 by TMHMM2.0 at aa 21-40, 97-119, 126-148, 188-210, 223-245, 272-294, 307-329, 334-356, 363-385, 400-418 and 425-447 272560006696 Pfam match to entry PF02366 PMT, Dolichyl-phosphate-mannose-protein mannosyltransferase , score 55.0, E-value 1e-13 272560006697 Xcc1710_like family, specific to proteobacteria. Xcc1710 is a hypothetical protein from Xanthomonas campestris pv. campestris str. ATCC 33913, similar to Mth938, a hypothetical protein encoded by the Methanobacterium thermoautotrophicum (Mth) genome; Region: Xcc1710_like; cd05560 272560006698 aminotransferase AlaT; Validated; Region: PRK09265 272560006699 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560006700 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560006701 homodimer interface [polypeptide binding]; other site 272560006702 catalytic residue [active] 272560006703 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 130.7, E-value 1.8e-36 272560006704 homoserine dehydrogenase; Provisional; Region: PRK06349 272560006705 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 272560006706 Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742 272560006707 ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881 272560006708 Pfam match to entry PF03447 NAD_binding_3, Homoserine dehydrogenase, NAD binding domain , score 179.0, E-value 5e-51 272560006709 Pfam match to entry PF00742 Homoserine_dh, Homoserine dehydrogenase , score 340.8, E-value 9.9e-100 272560006710 PS01042 Homoserine dehydrogenase signature. 272560006711 Pfam match to entry PF01842 ACT, ACT domain , score 51.6, E-value 1.2e-12 272560006712 threonine synthase; Validated; Region: PRK09225 272560006713 Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560 272560006714 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560006715 catalytic residue [active] 272560006716 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 96.0, E-value 5e-26 272560006717 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 272560006718 Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303 272560006719 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 272560006720 dimer interface [polypeptide binding]; other site 272560006721 putative functional site; other site 272560006722 putative MPT binding site; other site 272560006723 Pfam match to entry PF03453 MoeA_N, MoeA N-terminal region (domain I and II) , score 221.7, E-value 6.9e-64 272560006724 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain , score 165.1, E-value 7.6e-47 272560006725 PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 272560006726 Pfam match to entry PF03454 MoeA_C, MoeA C-terminal region (domain IV) , score 26.7, E-value 3.5e-05 272560006727 Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754 272560006728 MoaE interaction surface [polypeptide binding]; other site 272560006729 MoeB interaction surface [polypeptide binding]; other site 272560006730 thiocarboxylated glycine; other site 272560006731 Pfam match to entry PF02597 DUF170, ThiS family , score 25.8, E-value 6.5e-05 272560006732 MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756 272560006733 MoaE homodimer interface [polypeptide binding]; other site 272560006734 MoaD interaction [polypeptide binding]; other site 272560006735 active site residues [active] 272560006736 Pfam match to entry PF02391 MoaE, MoaE protein , score 161.0, E-value 1.4e-45 272560006737 Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454 272560006738 apolar tunnel; other site 272560006739 heme binding site [chemical binding]; other site 272560006740 dimerization interface [polypeptide binding]; other site 272560006741 Transcriptional regulator; Region: Rrf2; cl17282 272560006742 Rrf2 family protein; Region: rrf2_super; TIGR00738 272560006743 Pfam match to entry PF02082 UPF0074, Uncharacterized protein family UPF0074 , score 136.6, E-value 2.9e-38 272560006744 Predicted helix-turn-helix motif with score 1427.000, SD 4.05 at aa 25-46, sequence STIQEISDAYGISKNHLMKVVQ 272560006745 ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346 272560006746 Clp amino terminal domain; Region: Clp_N; pfam02861 272560006747 Clp amino terminal domain; Region: Clp_N; pfam02861 272560006748 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006749 Walker A motif; other site 272560006750 ATP binding site [chemical binding]; other site 272560006751 Walker B motif; other site 272560006752 arginine finger; other site 272560006753 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006754 Walker A motif; other site 272560006755 ATP binding site [chemical binding]; other site 272560006756 Walker B motif; other site 272560006757 arginine finger; other site 272560006758 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560006759 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain , score 46.0, E-value 5.5e-11 272560006760 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain , score 41.4, E-value 1.3e-09 272560006761 Predicted helix-turn-helix motif with score 1089.000, SD 2.90 at aa 131-152, sequence GEAGKLARQHGLTRRALESAIA 272560006762 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 50.2, E-value 3e-12 272560006763 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006764 PS00870 Chaperonins clpA/B signature 1. 272560006765 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 1.4, E-value 6.8e-05 272560006766 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006767 PS00871 Chaperonins clpA/B signature 2. 272560006768 Bacterial protein of unknown function (DUF937); Region: DUF937; cl01528 272560006769 Predicted helix-turn-helix motif with score 1096.000, SD 2.92 at aa 76-97, sequence DTIGALAQKVGIDPQQASGILA 272560006770 Helix-hairpin-helix motif; Region: HHH_3; pfam12836 272560006771 1 probable transmembrane helix predicted for BPSL1486 by TMHMM2.0 at aa 34-53 272560006772 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560006773 Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109 272560006774 DNA binding residues [nucleotide binding] 272560006775 putative dimer interface [polypeptide binding]; other site 272560006776 Predicted helix-turn-helix motif with score 1915.000, SD 5.71 at aa 13-34, sequence LTIGQVAALVGVSTHTLRYYEQ 272560006777 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 57.4, E-value 2.1e-14 272560006778 PS00552 Bacterial regulatory proteins, merR family signature. 272560006779 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599 272560006780 Pfam match to entry PF02627 CMD, Carboxymuconolactone decarboxylase , score 93.6, E-value 2.5e-25 272560006781 multidrug efflux protein; Reviewed; Region: PRK01766 272560006782 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 272560006783 cation binding site [ion binding]; other site 272560006784 12 probable transmembrane helices predicted for BPSL1489 by TMHMM2.0 at aa 12-34, 44-66, 87-109, 124-143, 155-177, 192-214, 235-257, 272-294, 314-336, 346-363, 380-402 and 417-439 272560006785 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 121.2, E-value 1.3e-33 272560006786 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 121.8, E-value 8.2e-34 272560006787 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807 272560006788 11 probable transmembrane helices predicted for BPSL1490 by TMHMM2.0 at aa 44-63, 128-150, 200-217, 232-254, 267-289, 324-343, 348-365, 375-392, 405-427, 447-466 and 479-501 272560006789 50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678 272560006790 Pfam match to entry PF01197 Ribosomal_L31, Ribosomal protein L31 , score 69.4, E-value 5e-18 272560006791 Glucose-regulated metallo-peptidase M90; Region: Peptidase_M90; pfam06167 272560006792 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560006793 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560006794 putative substrate translocation pore; other site 272560006795 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560006796 11 probable transmembrane helices predicted for BPSL1493 by TMHMM2.0 at aa 20-42, 57-79, 92-114, 146-168, 175-194, 209-228, 235-257, 277-299, 344-363, 378-400 and 490-512 272560006797 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560006798 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 272560006799 DNA binding residues [nucleotide binding] 272560006800 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 37.8, E-value 1.6e-08 272560006801 Predicted helix-turn-helix motif with score 1919.000, SD 5.72 at aa 10-31, sequence LTVRDAAERLGVTPRTLKYYEE 272560006802 transcription termination factor Rho; Provisional; Region: rho; PRK09376 272560006803 Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498 272560006804 Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459 272560006805 RNA binding site [nucleotide binding]; other site 272560006806 Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128 272560006807 multimer interface [polypeptide binding]; other site 272560006808 Walker A motif; other site 272560006809 ATP binding site [chemical binding]; other site 272560006810 Walker B motif; other site 272560006811 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 275.7, E-value 3.9e-80 272560006812 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006813 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 272560006814 catalytic residues [active] 272560006815 Pfam match to entry PF00085 thiored, Thioredoxin , score 167.9, E-value 1.1e-47 272560006816 PS00194 Thioredoxin family active site. 272560006817 DNA polymerase III subunits gamma and tau; Validated; Region: PRK07003 272560006818 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560006819 Walker A motif; other site 272560006820 ATP binding site [chemical binding]; other site 272560006821 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944 272560006822 Walker B motif; other site 272560006823 arginine finger; other site 272560006824 DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169 272560006825 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 24.4, E-value 9.6e-07 272560006826 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006827 High concentration of arginine and proline amino acid residues. Also high G+C content (82.26%) 272560006828 hypothetical protein; Validated; Region: PRK00153 272560006829 Pfam match to entry PF02575 DUF149, Uncharacterized BCR, YbaB family COG0718 , score 170.4, E-value 2e-48 272560006830 recombination protein RecR; Reviewed; Region: recR; PRK00076 272560006831 RecR protein; Region: RecR; pfam02132 272560006832 TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR. RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025 272560006833 putative active site [active] 272560006834 putative metal-binding site [ion binding]; other site 272560006835 tetramer interface [polypeptide binding]; other site 272560006836 Pfam match to entry PF02132 RecR, RecR protein , score 52.0, E-value 8.5e-13 272560006837 Pfam match to entry PF01751 Toprim, Toprim domain , score 40.2, E-value 3e-09 272560006838 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560006839 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 248.3, E-value 6.8e-72 272560006840 5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346 272560006841 Pfam match to entry PF01975 SurE, Survival protein SurE , score 272.5, E-value 3.6e-79 272560006842 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560006843 S-adenosylmethionine binding site [chemical binding]; other site 272560006844 Pfam match to entry PF01135 PCMT, Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) , score 228.2, E-value 7.7e-66 272560006845 Signal peptide predicted for BPSL1504 by SignalP 2.0 HMM (Signal peptide probabilty 0.969) with cleavage site probability 0.253 between residues 40 and 41; signal peptide 272560006846 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 272560006847 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560006848 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560006849 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560006850 Pfam match to entry PF01476 LysM, LysM domain , score 57.4, E-value 2e-14 272560006851 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 141.6, E-value 8.9e-40 272560006852 RNA polymerase sigma factor RpoS; Validated; Region: PRK05657 272560006853 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 272560006854 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560006855 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 272560006856 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560006857 DNA binding residues [nucleotide binding] 272560006858 Pfam match to entry PF00140 sigma70_r1_2, Sigma-70 factor, region 1.2 , score 42.9, E-value 4.6e-10 272560006859 PS00715 Sigma-70 factors family signature 1. 272560006860 Predicted helix-turn-helix motif with score 1993.000, SD 5.97 at aa 317-338, sequence ATLEELADEMGLTRERVRQIQQ 272560006861 PS00716 Sigma-70 factors family signature 2. 272560006862 Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782 272560006863 active site 272560006864 catalytic site [active] 272560006865 substrate binding site [chemical binding]; other site 272560006866 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108 272560006867 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 272560006868 putative catalytic site [active] 272560006869 putative metal binding site [ion binding]; other site 272560006870 putative phosphate binding site [ion binding]; other site 272560006871 putative catalytic site [active] 272560006872 putative phosphate binding site [ion binding]; other site 272560006873 putative metal binding site [ion binding]; other site 272560006874 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 63.9, E-value 2.3e-16 272560006875 23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168 272560006876 TRAM domain; Region: TRAM; cl01282 272560006877 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560006878 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560006879 S-adenosylmethionine binding site [chemical binding]; other site 272560006880 Pfam match to entry PF02475 Met_10, Met-10+ like-protein , score 20.4, E-value 4.1e-06 272560006881 YccA-like proteins; Region: YccA_like; cd10433 272560006882 Pfam match to entry PF01027 UPF0005, Uncharacterized protein family UPF0005 , score 95.5, E-value 6.9e-26 272560006883 7 probable transmembrane helices predicted for BPSL1509 by TMHMM2.0 at aa 33-55, 59-81, 88-110, 120-142, 149-171, 175-194 and 207-229 272560006884 Nucleoside diphosphate kinase; Region: NDK; pfam00334 272560006885 Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413 272560006886 active site 272560006887 multimer interface [polypeptide binding]; other site 272560006888 Pfam match to entry PF00334 NDK, Nucleoside diphosphate kinase , score 234.8, E-value 8.1e-68 272560006889 PS00469 Nucleoside diphosphate kinases active site. 272560006890 Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820 272560006891 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560006892 FeS/SAM binding site; other site 272560006893 Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426 272560006894 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560006895 non-specific DNA binding site [nucleotide binding]; other site 272560006896 salt bridge; other site 272560006897 sequence-specific DNA binding site [nucleotide binding]; other site 272560006898 Domain of unknown function (DUF4115); Region: DUF4115; pfam13464 272560006899 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366 272560006900 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612 272560006901 histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037 272560006902 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 272560006903 dimer interface [polypeptide binding]; other site 272560006904 motif 1; other site 272560006905 active site 272560006906 motif 2; other site 272560006907 motif 3; other site 272560006908 HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859 272560006909 anticodon binding site; other site 272560006910 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T) , score 152.8, E-value 3.8e-43 272560006911 Pfam match to entry PF03129 HGTP_anticodon, Anticodon binding domain , score 63.5, E-value 3e-16 272560006912 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976 272560006913 1 probable transmembrane helix predicted for BPSL1515 by TMHMM2.0 at aa 20-42 272560006914 outer membrane assembly lipoprotein YfgL; Region: assembly_YfgL; TIGR03300 272560006915 PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493 272560006916 Trp docking motif [polypeptide binding]; other site 272560006917 active site 272560006918 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 26.5, E-value 4.1e-05 272560006919 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 11.7, E-value 0.11 272560006920 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 22.6, E-value 0.00061 272560006921 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 14.6, E-value 0.039 272560006922 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 18.4, E-value 0.01 272560006923 Pfam match to entry PF01011 Bacterial_PQQ, PQQ enzyme repeat , score 6.1, E-value 0.71 272560006924 GTP-binding protein Der; Reviewed; Region: PRK00093 272560006925 EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894 272560006926 G1 box; other site 272560006927 GTP/Mg2+ binding site [chemical binding]; other site 272560006928 Switch I region; other site 272560006929 G2 box; other site 272560006930 Switch II region; other site 272560006931 G3 box; other site 272560006932 G4 box; other site 272560006933 G5 box; other site 272560006934 EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895 272560006935 G1 box; other site 272560006936 GTP/Mg2+ binding site [chemical binding]; other site 272560006937 Switch I region; other site 272560006938 G2 box; other site 272560006939 G3 box; other site 272560006940 Switch II region; other site 272560006941 G4 box; other site 272560006942 G5 box; other site 272560006943 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714 272560006944 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006945 Pfam match to entry PF01926 MMR_HSR1, GTPase of unknown function , score 219.0, E-value 4.5e-63 272560006946 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006947 bacterial Hfq-like; Region: Hfq; cd01716 272560006948 hexamer interface [polypeptide binding]; other site 272560006949 Sm1 motif; other site 272560006950 RNA binding site [nucleotide binding]; other site 272560006951 Sm2 motif; other site 272560006952 Pfam match to entry PF03329 Hfq, Host factor Hfq , score 140.9, E-value 1.5e-39 272560006953 GTP-binding protein HflX; Region: GTP_HflX; TIGR03156 272560006954 GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167 272560006955 HflX GTPase family; Region: HflX; cd01878 272560006956 G1 box; other site 272560006957 GTP/Mg2+ binding site [chemical binding]; other site 272560006958 Switch I region; other site 272560006959 G2 box; other site 272560006960 G3 box; other site 272560006961 Switch II region; other site 272560006962 G4 box; other site 272560006963 G5 box; other site 272560006964 PS00017 ATP/GTP-binding site motif A (P-loop). 272560006965 Bacterial membrane protein N terminal; Region: HflK_N; pfam12221 272560006966 High frequency of lysogenization K (HflK) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflK; cd03404 272560006967 HflK protein; Region: hflK; TIGR01933 272560006968 1 probable transmembrane helix predicted for BPSL1520 by TMHMM2.0 at aa 95-117 272560006969 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family , score 102.9, E-value 4.1e-28 272560006970 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 272560006971 High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflC; cd03405 272560006972 1 probable transmembrane helix predicted for BPSL1521 by TMHMM2.0 at aa 5-24 272560006973 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family , score 111.3, E-value 1.2e-30 272560006974 Uncharacterized protein conserved in bacteria (DUF2065); Region: DUF2065; pfam09838 272560006975 2 probable transmembrane helices predicted for BPSL1522 by TMHMM2.0 at aa 7-29 and 44-62 272560006976 ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: PRK12421 272560006977 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773 272560006978 dimer interface [polypeptide binding]; other site 272560006979 motif 1; other site 272560006980 active site 272560006981 motif 2; other site 272560006982 motif 3; other site 272560006983 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T) , score -3.5, E-value 6.8e-05 272560006984 Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108 272560006985 GDP-binding site [chemical binding]; other site 272560006986 ACT binding site; other site 272560006987 IMP binding site; other site 272560006988 Pfam match to entry PF00709 Adenylsucc_synt, Adenylosuccinate synthetase , score 899.4, E-value 6.8e-268 272560006989 PS01266 Adenylosuccinate synthetase GTP-binding site. 272560006990 PS00513 Adenylosuccinate synthetase active site. 272560006991 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560006992 active site 272560006993 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 31.8, E-value 1e-06 272560006994 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 272560006995 K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158 272560006996 11 probable transmembrane helices predicted for BPSL1526 by TMHMM2.0 at aa 13-35, 55-77, 105-127, 142-164, 176-198, 218-240, 253-275, 341-363, 370-392, 402-424 and 431-448 272560006997 Pfam match to entry PF02705 K_trans, K+ potassium transporter , score 566.2, E-value 1.3e-167 272560006998 Transcriptional accessory protein [Transcription]; Region: Tex; COG2183 272560006999 Tex-like protein N-terminal domain; Region: Tex_N; pfam09371 272560007000 Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732 272560007001 Uncharacterized protein family (UPF0081); Region: UPF0081; cl17278 272560007002 Helix-hairpin-helix motif; Region: HHH_3; pfam12836 272560007003 S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685 272560007004 RNA binding site [nucleotide binding]; other site 272560007005 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 96.4, E-value 3.7e-26 272560007006 Signal peptide predicted for BPSL1531 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.461 between residues 36 and 37; signal peptide 272560007007 MAEBL; Provisional; Region: PTZ00121 272560007008 Protein of unknown function (DUF465); Region: DUF465; pfam04325 272560007009 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 272560007010 CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cd09708 272560007011 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 272560007012 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007013 Signal peptide predicted for BPSL1531 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.695 between residues 30 and 31; signal peptide 272560007014 outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302 272560007015 Pfam match to entry PF03696 UPF0169, Uncharacterised protein family (UPF0169) , score 276.3, E-value 2.5e-80 272560007016 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007017 23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180 272560007018 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560007019 RNA binding surface [nucleotide binding]; other site 272560007020 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 272560007021 active site 272560007022 Protein of unknown function (DUF3073); Region: DUF3073; pfam11273 272560007023 Pfam match to entry PF01479 S4, S4 domain , score 31.7, E-value 1.1e-06 272560007024 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 211.9, E-value 6.4e-61 272560007025 PS01129 Rlu family of pseudouridine synthase signature. 272560007026 Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; cl00650 272560007027 Pfam match to entry PF02578 DUF152, Uncharacterized ACR, YfiH family COG1496 , score 232.3, E-value 4.5e-67 272560007028 poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838 272560007029 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167 272560007030 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 59.4, E-value 5.1e-15 272560007031 putative acyltransferase; Provisional; Region: PRK05790 272560007032 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560007033 dimer interface [polypeptide binding]; other site 272560007034 active site 272560007035 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 568.7, E-value 2.4e-168 272560007036 PS00098 Thiolases acyl-enzyme intermediate signature. 272560007037 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 277.5, E-value 1.1e-80 272560007038 PS00737 Thiolases signature 2. 272560007039 PS00099 Thiolases active site. 272560007040 acetyacetyl-CoA reductase; Provisional; Region: PRK12938 272560007041 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 272560007042 NAD(P) binding site [chemical binding]; other site 272560007043 homotetramer interface [polypeptide binding]; other site 272560007044 homodimer interface [polypeptide binding]; other site 272560007045 active site 272560007046 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 339.9, E-value 1.8e-99 272560007047 PS00061 Short-chain dehydrogenases/reductases family signature. 272560007048 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5394 272560007049 PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879 272560007050 PHB accumulation regulatory domain; Region: PHB_acc; pfam05233 272560007051 PHB accumulation regulatory domain; Region: PHB_acc; pfam05233 272560007052 ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862 272560007053 Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919 272560007054 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560007055 FeS/SAM binding site; other site 272560007056 TRAM domain; Region: TRAM; cl01282 272560007057 Pfam match to entry PF00919 UPF0004, Uncharacterized protein family UPF0004 , score 123.1, E-value 3.5e-34 272560007058 PS01278 Uncharacterized protein family UPF0004 signature. 272560007059 Pfam match to entry PF01938 TRAM, TRAM domain , score 13.2, E-value 0.018 272560007060 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 272560007061 substrate binding site [chemical binding]; other site 272560007062 ATP binding site [chemical binding]; other site 272560007063 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 234.6, E-value 9.1e-68 272560007064 beta-ketothiolase; Provisional; Region: PRK09051 272560007065 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560007066 dimer interface [polypeptide binding]; other site 272560007067 active site 272560007068 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 428.0, E-value 5.5e-126 272560007069 PS00098 Thiolases acyl-enzyme intermediate signature. 272560007070 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 236.3, E-value 2.9e-68 272560007071 PS00099 Thiolases active site. 272560007072 Signal peptide predicted for BPSL1541 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.509 between residues 32 and 33; signal peptide 272560007073 cystathionine beta-lyase; Provisional; Region: PRK07050 272560007074 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560007075 catalytic residue [active] 272560007076 Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme , score 267.9, E-value 8.8e-78 272560007077 Domain of unknown function (DUF4072); Region: DUF4072; pfam13284 272560007078 haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702 272560007079 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560007080 motif II; other site 272560007081 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 93.9, E-value 2.1e-25 272560007082 Signal peptide predicted for BPSL1544 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 26 and 27; signal peptide 272560007083 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG0390 272560007084 Pfam match to entry PF03649 UPF0014, Uncharacterised protein family (UPF0014) , score 184.2, E-value 1.4e-52 272560007085 7 probable transmembrane helices predicted for BPSL1545 by TMHMM2.0 at aa 10-32, 39-61, 65-87, 99-121, 126-148, 191-213 and 223-245 272560007086 ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4619 272560007087 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560007088 Walker A/P-loop; other site 272560007089 ATP binding site [chemical binding]; other site 272560007090 Q-loop/lid; other site 272560007091 ABC transporter signature motif; other site 272560007092 Walker B; other site 272560007093 D-loop; other site 272560007094 H-loop/switch region; other site 272560007095 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 163.1, E-value 3.1e-46 272560007096 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007097 Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982 272560007098 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 272560007099 1 probable transmembrane helix predicted for BPSL1547 by TMHMM2.0 at aa 12-34 272560007100 ABC transporter ATP-binding protein; Provisional; Region: PRK15064 272560007101 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560007102 ABC transporter; Region: ABC_tran_2; pfam12848 272560007103 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560007104 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 132.3, E-value 5.7e-37 272560007105 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007106 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 125.0, E-value 9e-35 272560007107 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007108 Burkholderia Lethal Factor 1; Region: BPSL1549; cd12812 272560007109 Rhodococcus ruber 6-oxolauric acid dehydrogenase-like; Region: ALDH_CddD_SSP0762; cd07138 272560007110 NAD binding site [chemical binding]; other site 272560007111 catalytic residues [active] 272560007112 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 589.9, E-value 9.9e-175 272560007113 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007114 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560007115 PS00070 Aldehyde dehydrogenases cysteine active site. 272560007116 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 272560007117 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 272560007118 FMN binding site [chemical binding]; other site 272560007119 substrate binding site [chemical binding]; other site 272560007120 putative catalytic residue [active] 272560007121 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase , score 31.2, E-value 3.8e-10 272560007122 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 272560007123 Pfam match to entry PF03922 OmpW, OmpW family , score 175.6, E-value 5.4e-50 272560007124 Predicted Fe-S protein [General function prediction only]; Region: COG3313 272560007125 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845 272560007126 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 272560007127 11 probable transmembrane helices predicted for BPSL1554 by TMHMM2.0 at aa 24-43, 58-80, 106-128, 133-155, 162-184, 208-227, 255-277, 303-325, 345-367, 372-394 and 407-429 272560007128 Pfam match to entry PF01566 Nramp, Natural resistance-associated macrophage protein , score 412.6, E-value 2.4e-121 272560007129 Signal peptide predicted for BPSL1555 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.896 between residues 23 and 24; signal peptide 272560007130 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 272560007131 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 70.6, E-value 2.2e-18 272560007132 putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607 272560007133 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560007134 Walker A/P-loop; other site 272560007135 ATP binding site [chemical binding]; other site 272560007136 Q-loop/lid; other site 272560007137 ABC transporter signature motif; other site 272560007138 Walker B; other site 272560007139 D-loop; other site 272560007140 H-loop/switch region; other site 272560007141 TOBE domain; Region: TOBE_2; pfam08402 272560007142 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 232.5, E-value 3.9e-67 272560007143 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007144 PS00211 ABC transporters family signature. 272560007145 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560007146 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560007147 dimer interface [polypeptide binding]; other site 272560007148 conserved gate region; other site 272560007149 putative PBP binding loops; other site 272560007150 ABC-ATPase subunit interface; other site 272560007151 6 probable transmembrane helices predicted for BPSL1557 by TMHMM2.0 at aa 21-43, 85-107, 127-149, 176-198, 219-241 and 277-299 272560007152 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 68.1, E-value 1.2e-17 272560007153 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560007154 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560007155 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560007156 dimer interface [polypeptide binding]; other site 272560007157 conserved gate region; other site 272560007158 putative PBP binding loops; other site 272560007159 ABC-ATPase subunit interface; other site 272560007160 6 probable transmembrane helices predicted for BPSL1558 by TMHMM2.0 at aa 7-29, 65-87, 100-122, 137-159, 180-202 and 239-261 272560007161 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 49.5, E-value 4.8e-12 272560007162 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560007163 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 272560007164 8 probable transmembrane helices predicted for BPSL1559 by TMHMM2.0 at aa 10-32, 44-66, 70-89, 96-113, 152-174, 186-208, 218-237 and 244-266 272560007165 Pfam match to entry PF01925 DUF81, Domain of unknown function DUF81 , score 30.9, E-value 2e-06 272560007166 Putative phosphatase (DUF442); Region: DUF442; cl17385 272560007167 pyridine nucleotide-disulfide oxidoreductase family protein; Region: Nterm_to_SelD; TIGR03169 272560007168 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 272560007169 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 90.5, E-value 2.2e-24 272560007170 PAS fold; Region: PAS_4; pfam08448 272560007171 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560007172 putative active site [active] 272560007173 heme pocket [chemical binding]; other site 272560007174 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560007175 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560007176 Walker A motif; other site 272560007177 ATP binding site [chemical binding]; other site 272560007178 Walker B motif; other site 272560007179 arginine finger; other site 272560007180 Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cl17393 272560007181 DNA-binding interface [nucleotide binding]; DNA binding site 272560007182 Pfam match to entry PF00989 PAS, PAS domain , score 17.2, E-value 0.00024 272560007183 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 374.0, E-value 9.7e-110 272560007184 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560007185 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560007186 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560007187 Predicted helix-turn-helix motif with score 2314.000, SD 7.07 at aa 437-458, sequence GTRRALAERVGMSERTLYRRLR 272560007188 4 probable transmembrane helices predicted for BPSL1563 by TMHMM2.0 at aa 13-35, 71-93, 118-139 and 154-173 272560007189 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007190 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560007191 sequence-specific DNA binding site [nucleotide binding]; other site 272560007192 salt bridge; other site 272560007193 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 16-37, sequence VRSKDLAAAVGITEQNLSLLKQ 272560007194 DNA polymerase III subunits gamma and tau; Provisional; Region: PRK12323 272560007195 Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047 272560007196 Helix-Turn-Helix DNA binding domain of the transcription regulators NolA and AlbR; Region: HTH_NolA-AlbR; cd04788 272560007197 DNA binding residues [nucleotide binding] 272560007198 putative dimer interface [polypeptide binding]; other site 272560007199 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 272560007200 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 272560007201 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 66.9, E-value 2.8e-17 272560007202 PS00552 Bacterial regulatory proteins, merR family signature. 272560007203 Predicted helix-turn-helix motif with score 1618.000, SD 4.70 at aa 9-30, sequence LKIGELAKRCGLTVRTLHHYDA 272560007204 Signal peptide predicted for BPSL1566 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.650 between residues 25 and 26; signal peptide 272560007205 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560007206 Outer membrane efflux protein; Region: OEP; pfam02321 272560007207 Outer membrane efflux protein; Region: OEP; pfam02321 272560007208 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 132.8, E-value 4.1e-37 272560007209 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 78.6, E-value 8.4e-21 272560007210 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007211 Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841 272560007212 MMPL family; Region: MMPL; cl14618 272560007213 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 251.8, E-value 6.1e-73 272560007214 11 probable transmembrane helices predicted for BPSL1567 by TMHMM2.0 at aa 21-43, 348-370, 375-394, 404-426, 438-460, 480-502, 553-575, 912-934, 936-958, 986-1008 and 1015-1037 272560007215 PS00589 PTS HPR component serine phosphorylation site signature. 272560007216 PS00152 ATP synthase alpha and beta subunits signature. 272560007217 Signal peptide predicted for BPSL1568 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.463 between residues 23 and 24; signal peptide 272560007218 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 272560007219 Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169 272560007220 Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169 272560007221 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560007222 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007223 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560007224 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560007225 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 62.3, E-value 6.9e-16 272560007226 putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862 272560007227 CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400 272560007228 Cl- selectivity filter; other site 272560007229 Cl- binding residues [ion binding]; other site 272560007230 pore gating glutamate residue; other site 272560007231 dimer interface [polypeptide binding]; other site 272560007232 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205 272560007233 Pfam match to entry PF00571 CBS, CBS domain , score 22.3, E-value 0.00076 272560007234 Pfam match to entry PF00571 CBS, CBS domain , score 27.4, E-value 2.1e-05 272560007235 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007236 Pfam match to entry PF00654 voltage_CLC, Voltage gated chloride channel , score 118.9, E-value 6e-33 272560007237 9 probable transmembrane helices predicted for BPSL1570 by TMHMM2.0 at aa 57-74, 105-122, 225-247, 262-284, 305-327, 342-364, 371-393, 403-425 and 432-454 272560007238 Predicted membrane protein [Function unknown]; Region: COG2855 272560007239 8 probable transmembrane helices predicted for BPSL1571 by TMHMM2.0 at aa 20-37, 42-64, 105-127, 137-159, 166-188, 235-252, 273-295 and 329-351 272560007240 Pfam match to entry PF03601 Cons_hypoth698, Conserved hypothetical protein 698 , score 348.7, E-value 4.1e-102 272560007241 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560007242 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560007243 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560007244 dimerization interface [polypeptide binding]; other site 272560007245 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 89.7, E-value 3.9e-24 272560007246 Predicted helix-turn-helix motif with score 1090.000, SD 2.90 at aa 7-28, sequence ITFAAVAEHRNISRAALALHLS 272560007247 Predicted helix-turn-helix motif with score 1556.000, SD 4.49 at aa 16-37, sequence RNISRAALALHLSQPAVSGQLR 272560007248 Predicted helix-turn-helix motif with score 1090.000, SD 2.90 at aa 16-28, sequence RNISRAALALHLS 272560007249 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 167.1, E-value 2e-47 272560007250 SdpI/YhfL protein family; Region: SdpI; pfam13630 272560007251 3 probable transmembrane helices predicted for BPSL1573 by TMHMM2.0 at aa 32-54, 78-95 and 108-130 272560007252 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 272560007253 substrate binding site [chemical binding]; other site 272560007254 ATP binding site [chemical binding]; other site 272560007255 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 246.3, E-value 2.7e-71 272560007256 PS00584 pfkB family of carbohydrate kinases signature 2. 272560007257 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560007258 D-galactonate transporter; Region: 2A0114; TIGR00893 272560007259 putative substrate translocation pore; other site 272560007260 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -48.3, E-value 4e-06 272560007261 12 probable transmembrane helices predicted for BPSL1576 by TMHMM2.0 at aa 7-26, 50-72, 79-101, 105-127, 140-162, 166-188, 231-253, 263-285, 298-317, 322-344, 357-379 and 389-408 272560007262 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 272560007263 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 272560007264 dimerization interface [polypeptide binding]; other site 272560007265 ligand binding site [chemical binding]; other site 272560007266 NADP binding site [chemical binding]; other site 272560007267 catalytic site [active] 272560007268 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 73.8, E-value 2.4e-19 272560007269 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 255.9, E-value 3.7e-74 272560007270 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007271 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560007272 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 272560007273 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560007274 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560007275 DNA binding site [nucleotide binding] 272560007276 domain linker motif; other site 272560007277 Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; Region: PBP1_RegR_EndR_KdgR_like; cd06283 272560007278 putative dimerization interface [polypeptide binding]; other site 272560007279 putative ligand binding site [chemical binding]; other site 272560007280 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family , score 34.6, E-value 1.5e-07 272560007281 Predicted helix-turn-helix motif with score 1673.000, SD 4.89 at aa 12-33, sequence ATISDVAREAGTGKTSVSRYLN 272560007282 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 2.4, E-value 1.1e-05 272560007283 Putative membrane peptidase family (DUF2324); Region: DUF2324; pfam10086 272560007284 7 probable transmembrane helices predicted for BPSL1579 by TMHMM2.0 at aa 6-28, 41-63, 76-98, 118-140, 176-198, 207-226 and 236-255 272560007285 Protein of unknown function (DUF3022); Region: DUF3022; pfam11226 272560007286 PGDYG protein; Region: PGDYG; pfam14083 272560007287 Signal peptide predicted for BPSL1583 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.896 between residues 27 and 28; signal peptide 272560007288 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560007289 1 probable transmembrane helix predicted for BPSL1582 by TMHMM2.0 at aa 13-35 272560007290 Signal peptide predicted for BPSL1583 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.673 between residues 21 and 22; signal peptide 272560007291 LTXXQ motif family protein; Region: LTXXQ; pfam07813 272560007292 Predicted helix-turn-helix motif with score 1272.000, SD 3.52 at aa 47-68, sequence ERITYLHNQLKITPEQESQWKT 272560007293 Similar to internal regions of Streptomyces verticillus peptide synthetase NRPS12 SWALL:Q9FB39 (EMBL:AF210249) (578 aa) fasta scores: E(): 7.3e-19, 41.29% id in 201 aa, and Streptomyces lavendulae peptide synthetase SWALL:Q93N89 (EMBL:AF386507) (2116 aa) fasta scores: E(): 3.3e-18, 45.4% id in 174 aa; peptide synthetase (fragment) 272560007294 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 103.6, E-value 8e-29 272560007295 Similar to the C-terminal region of Pseudomonas aeruginosa probable nonribosomal peptide synthetase pa4078 SWALL:Q9HWV0 (EMBL:AE004823) (991 aa) fasta scores: E(): 3.6e-61, 60.9% id in 266 aa, and Myxococcus xanthus saframycin MX1 synthetase A SafA SWALL:Q50858 (EMBL:U24657) (2605 aa) fasta scores: E(): 5e-16, 32.35% id in 272 aa; nonribosomal peptide synthase (fragment) 272560007296 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007297 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560007298 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560007299 Predicted helix-turn-helix motif with score 1041.000, SD 2.73 at aa 26-47, sequence ASVADLARQLGVARTTVLARIA 272560007300 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 43.7, E-value 2.6e-10 272560007301 Double zinc ribbon; Region: DZR; pfam12773 272560007302 4 probable transmembrane helices predicted for BPSL1589 by TMHMM2.0 at aa 13-35, 183-205, 212-234 and 239-261 272560007303 1 probable transmembrane helix predicted for BPSL1590 by TMHMM2.0 at aa 62-84 272560007304 Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748 272560007305 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560007306 AAA domain; Region: AAA_17; cl19128 272560007307 AAA domain; Region: AAA_33; pfam13671 272560007308 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007309 pseudogene. Similar to Vibrio cholerae hypothetical protein vc1842 SWALL:Q9KR05 (EMBL:AE004260) (35 aa) fasta scores: E(): 7.6e-06, 61.29% id in 31 aa, and to Brucella melitensis protein bmeii0758 SWALL:Q8YBX8 (EMBL:AE009710) (51 aa) fasta scores: E(): 4.8e-05, 51.35% id in 37 aa;conserved hypothetical protein (pseudogene) 272560007310 CorA-like Mg2+ transporter protein; Region: CorA; pfam01544 272560007311 Mycobacterium tuberculosis CorA-like subfamily; Region: MtCorA-like; cd12830 272560007312 oligomer interface [polypeptide binding]; other site 272560007313 metal binding site [ion binding]; metal-binding site 272560007314 metal binding site [ion binding]; metal-binding site 272560007315 putative Cl binding site [ion binding]; other site 272560007316 basic sphincter; other site 272560007317 hydrophobic gate; other site 272560007318 periplasmic entrance; other site 272560007319 Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein , score 210.3, E-value 1.9e-60 272560007320 2 probable transmembrane helices predicted for BPSL1593 by TMHMM2.0 at aa 279-298 and 308-327 272560007321 YciI-like protein; Reviewed; Region: PRK12866 272560007322 Pfam match to entry PF03795 YCII, YCII-related domain , score 53.0, E-value 4.3e-13 272560007323 Signal peptide predicted for BPSL1595 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.871 between residues 24 and 25; signal peptide 272560007324 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558 272560007325 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007326 Signal peptide predicted for BPSL1596 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.985 between residues 34 and 35; signal peptide 272560007327 2 probable transmembrane helices predicted for BPSL1597 by TMHMM2.0 at aa 33-55 and 65-87 272560007328 Signal peptide predicted for BPSL1598 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.987 between residues 28 and 29; signal peptide 272560007329 Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: COG3264 272560007330 Protein of unknown function (DUF3772); Region: DUF3772; pfam12607 272560007331 Mechanosensitive ion channel; Region: MS_channel; pfam00924 272560007332 Pfam match to entry PF00924 MS_channel, Mechanosensitive ion channel , score 162.3, E-value 5.3e-46 272560007333 9 probable transmembrane helices predicted for BPSL1598 by TMHMM2.0 at aa 261-283, 336-358, 371-393, 413-435, 442-464, 499-521, 546-568, 588-610 and 617-636 272560007334 Signal peptide predicted for BPSL1599 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.844 between residues 25 and 26; signal peptide 272560007335 Regulator of nitric oxide reductase transcription [Transcription]; Region: NosR; COG3901 272560007336 ferredoxin-type protein, NapH/MauN family; Region: napH_; TIGR02163 272560007337 4Fe-4S binding domain; Region: Fer4_5; pfam12801 272560007338 4Fe-4S binding domain; Region: Fer4_5; pfam12801 272560007339 4Fe-4S dicluster domain; Region: Fer4_7; pfam12838 272560007340 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560007341 PS00190 Cytochrome c family heme-binding site signature. 272560007342 5 probable transmembrane helices predicted for BPSL1599 by TMHMM2.0 at aa 408-425, 446-468, 483-505, 552-569 and 584-606 272560007343 Signal peptide predicted for BPSL1600 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.716 between residues 34 and 35; signal peptide 272560007344 Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245 272560007345 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 21.7, E-value 0.00017 272560007346 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007347 Signal peptide predicted for BPSL1603 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.384 between residues 20 and 21; signal peptide 272560007348 NosL; Region: NosL; pfam05573 272560007349 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007350 ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679 272560007351 6 probable transmembrane helices predicted for BPSL1604 by TMHMM2.0 at aa 29-51, 62-84, 114-136, 151-173, 186-208 and 250-272 272560007352 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 272560007353 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560007354 Walker A/P-loop; other site 272560007355 ATP binding site [chemical binding]; other site 272560007356 Q-loop/lid; other site 272560007357 ABC transporter signature motif; other site 272560007358 Walker B; other site 272560007359 D-loop; other site 272560007360 H-loop/switch region; other site 272560007361 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 194.0, E-value 1.5e-55 272560007362 PS00211 ABC transporters family signature. 272560007363 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007364 nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247 272560007365 parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804 272560007366 parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804 272560007367 nitrous-oxide reductase; Validated; Region: PRK02888 272560007368 The C-terminal cupredoxin domain of Nitrous-oxide reductase; Region: N2OR_C; cd04223 272560007369 dimer interface [polypeptide binding]; other site 272560007370 CuA binuclear site [ion binding]; other site 272560007371 Signal peptide predicted for BPSL1608 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.364 between residues 33 and 34; signal peptide 272560007372 ApbE family; Region: ApbE; pfam02424 272560007373 Pfam match to entry PF02424 ApbE, ApbE family , score 192.0, E-value 6.2e-55 272560007374 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 272560007375 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560007376 Walker A/P-loop; other site 272560007377 ATP binding site [chemical binding]; other site 272560007378 Q-loop/lid; other site 272560007379 ABC transporter signature motif; other site 272560007380 Walker B; other site 272560007381 D-loop; other site 272560007382 H-loop/switch region; other site 272560007383 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 195.8, E-value 4.5e-56 272560007384 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007385 PS00211 ABC transporters family signature. 272560007386 ABC-2 type transporter; Region: ABC2_membrane; cl17235 272560007387 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560007388 6 probable transmembrane helices predicted for BPSL1610 by TMHMM2.0 at aa 20-39, 54-76, 97-116, 131-153, 160-182 and 223-242 272560007389 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560007390 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560007391 dimerization interface [polypeptide binding]; other site 272560007392 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560007393 dimer interface [polypeptide binding]; other site 272560007394 putative CheW interface [polypeptide binding]; other site 272560007395 2 probable transmembrane helices predicted for BPSL1611 by TMHMM2.0 at aa 10-32 and 172-194 272560007396 Pfam match to entry PF00672 HAMP, HAMP domain , score 50.5, E-value 2.4e-12 272560007397 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 280.5, E-value 1.4e-81 272560007398 dihydroxyacetone kinase; Provisional; Region: PRK14479 272560007399 Dak1 domain; Region: Dak1; cl10557 272560007400 DAK2 domain; Region: Dak2; pfam02734 272560007401 Pfam match to entry PF02733 Dak1, Dak1 domain , score 468.9, E-value 2.7e-138 272560007402 Pfam match to entry PF02734 Dak2, DAK2 domain , score 106.5, E-value 3.4e-29 272560007403 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560007404 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560007405 iron-sulfur cluster [ion binding]; other site 272560007406 [2Fe-2S] cluster binding site [ion binding]; other site 272560007407 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 93.4, E-value 2.9e-25 272560007408 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 272560007409 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 13.3, E-value 1.4e-06 272560007410 13 probable transmembrane helices predicted for BPSL1616 by TMHMM2.0 at aa 15-37, 50-72, 82-101, 114-136, 146-168, 180-202, 217-239, 246-265, 269-286, 298-317, 327-349, 361-383 and 387-409 272560007411 PS00436 Peroxidases active site signature. 272560007412 geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032 272560007413 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560007414 Pfam match to entry PF01494 FAD_binding_3, FAD binding domain , score 17.4, E-value 7.8e-07 272560007415 Similar to Bacillus methanolicus NAD-dependent methanol dehydrogenase Mdh SWALL:MEDH_BACMT (SWALL:P31005) (380 aa) fasta scores: E(): 1.3e-79, 56.46% id in 379 aa, and to Klebsiella pneumoniae 1,3-propanediol dehydrogenase DhaT SWALL:DHAT_KLEPN (SWALL:Q59477) (387 aa) fasta scores: E(): 1.2e-74, 54.3% id in 383 aa. CDS contains a frameshift after codon 285; alcohol dehydrogenase (pseudogene) 272560007416 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase , score 359.5, E-value 2.4e-105 272560007417 PS00913 Iron-containing alcohol dehydrogenases signature 1. 272560007418 PS00060 Iron-containing alcohol dehydrogenases signature 2. 272560007419 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase , score 100.4, E-value 3.1e-29 272560007420 Signal peptide predicted for BPSL1622 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 29 and 30; signal peptide 272560007421 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560007422 MEKHLA domain; Region: MEKHLA; pfam08670 272560007423 Signal peptide predicted for BPSL1626 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.872 between residues 25 and 26; signal peptide 272560007424 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 272560007425 Pfam match to entry PF00419 Fimbrial, Fimbrial protein , score 117.1, E-value 2.2e-32 272560007426 Signal peptide predicted for BPSL1627 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 24 and 25; signal peptide 272560007427 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 272560007428 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560007429 Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753 272560007430 Pfam match to entry PF00345 pili_assembly, Gram-negative pili assembly chaperone, N-terminal domain , score 136.7, E-value 2.8e-38 272560007431 Pfam match to entry PF02753 pili_assembly_C, Gram-negative pili assembly chaperone, C-terminal domain , score 41.4, E-value 1.3e-09 272560007432 Signal peptide predicted for BPSL1628 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.485 between residues 30 and 31; signal peptide 272560007433 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560007434 PapC N-terminal domain; Region: PapC_N; pfam13954 272560007435 Outer membrane usher protein; Region: Usher; pfam00577 272560007436 PapC C-terminal domain; Region: PapC_C; pfam13953 272560007437 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score 969.6, E-value 5.1e-289 272560007438 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 272560007439 PS01151 Fimbrial biogenesis outer membrane usher protein signature. 272560007440 PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 272560007441 Signal peptide predicted for BPSL1629 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.936 between residues 32 and 33; signal peptide 272560007442 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 272560007443 Pfam match to entry PF00419 Fimbrial, Fimbrial protein , score 72.2, E-value 6.9e-19 272560007444 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560007445 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560007446 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560007447 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007448 trimer interface [polypeptide binding]; other site 272560007449 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007450 trimer interface [polypeptide binding]; other site 272560007451 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007452 trimer interface [polypeptide binding]; other site 272560007453 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007454 trimer interface [polypeptide binding]; other site 272560007455 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007456 trimer interface [polypeptide binding]; other site 272560007457 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560007458 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560007459 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 25.6, E-value 5.2e-06 272560007460 2 probable transmembrane helices predicted for BPSL1632 by TMHMM2.0 at aa 30-52 and 58-80 272560007461 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560007462 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560007463 active site 272560007464 phosphorylation site [posttranslational modification] 272560007465 intermolecular recognition site; other site 272560007466 dimerization interface [polypeptide binding]; other site 272560007467 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560007468 DNA binding residues [nucleotide binding] 272560007469 dimerization interface [polypeptide binding]; other site 272560007470 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 48.9, E-value 7.3e-12 272560007471 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 47.2, E-value 2.4e-11 272560007472 Predicted helix-turn-helix motif with score 1495.000, SD 4.28 at aa 176-197, sequence MSLTDIARTLNRSLGTVSTQKR 272560007473 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 272560007474 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560007475 dimer interface [polypeptide binding]; other site 272560007476 phosphorylation site [posttranslational modification] 272560007477 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560007478 ATP binding site [chemical binding]; other site 272560007479 Mg2+ binding site [ion binding]; other site 272560007480 G-X-G motif; other site 272560007481 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560007482 active site 272560007483 phosphorylation site [posttranslational modification] 272560007484 intermolecular recognition site; other site 272560007485 dimerization interface [polypeptide binding]; other site 272560007486 2 probable transmembrane helices predicted for BPSL1634 by TMHMM2.0 at aa 31-53 and 323-345 272560007487 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 80.1, E-value 3e-21 272560007488 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 151.8, E-value 8e-43 272560007489 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 122.3, E-value 5.7e-34 272560007490 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560007491 Pfam match to entry PF00563 EAL, EAL domain , score 142.3, E-value 5.7e-40 272560007492 H-NS histone family; Region: Histone_HNS; pfam00816 272560007493 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560007494 Genomic island GI 8 272560007495 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 272560007496 nucleophilic elbow; other site 272560007497 catalytic triad; other site 272560007498 Pfam match to entry PF01764 Lipase_3, Lipase (class 3) , score 47.8, E-value 1.6e-11 272560007499 PS00120 Lipases, serine active site. 272560007500 Similarity to an internal region of Bacteriophage phiE125 protein GP31 SWALL:Q8W6S0 (EMBL:AF447491) (363 aa) fasta scores: E(): 2e-10, 45% id in 100 aa; phage-related protein (fragment) 272560007501 Similar to the N-terminal regions of Rhizobium meliloti transposase for insertion sequence element ISRm3 SWALL:TRA3_RHIME (SWALL:P80011) (400 aa) fasta scores: E(): 6e-29, 45.77% id in 225 aa, and Alcaligenes eutrophus insertion sequence IS1090 SWALL:Q9RBF5 (EMBL:AJ010060) (416 aa) fasta scores: E(): 9.2e-37, 51.23% id in 244 aa. CDS is truncated at the C-terminus and contains several nonsense mutations; transposase (fragment) 272560007502 Pfam match to entry PF00872 Transpo_mutator, Transposase, Mutator family , score 111.6, E-value 4.6e-32 272560007503 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560007504 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560007505 DNA-binding site [nucleotide binding]; DNA binding site 272560007506 FCD domain; Region: FCD; pfam07729 272560007507 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 62.3, E-value 6.8e-16 272560007508 PS00043 Bacterial regulatory proteins, gntR family signature. 272560007509 Amino acid synthesis; Region: AA_synth; pfam06684 272560007510 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560007511 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560007512 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 80.7, E-value 2e-21 272560007513 PS00221 MIP family signature. 272560007514 Flavin reductase like domain; Region: Flavin_Reduct; smart00903 272560007515 Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain , score 190.5, E-value 1.7e-54 272560007516 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 272560007517 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases [Energy production and conversion]; Region: COG2141 272560007518 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score 119.6, E-value 3.8e-33 272560007519 Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114 272560007520 NAD(P) binding site [chemical binding]; other site 272560007521 catalytic residues [active] 272560007522 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 589.5, E-value 1.3e-174 272560007523 PS00213 Lipocalin signature. 272560007524 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560007525 PS00070 Aldehyde dehydrogenases cysteine active site. 272560007526 NIPSNAP; Region: NIPSNAP; pfam07978 272560007527 Signal peptide predicted for BPSL1649 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.975 between residues 15 and 16; signal peptide 272560007528 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 272560007529 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 43.7, E-value 2.7e-10 272560007530 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560007531 dimer interface [polypeptide binding]; other site 272560007532 putative PBP binding loops; other site 272560007533 ABC-ATPase subunit interface; other site 272560007534 6 probable transmembrane helices predicted for BPSL1650 by TMHMM2.0 at aa 27-49, 78-100, 107-129, 153-175, 215-237 and 257-279 272560007535 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 68.6, E-value 8.8e-18 272560007536 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560007537 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560007538 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560007539 dimer interface [polypeptide binding]; other site 272560007540 conserved gate region; other site 272560007541 putative PBP binding loops; other site 272560007542 ABC-ATPase subunit interface; other site 272560007543 6 probable transmembrane helices predicted for BPSL1651 by TMHMM2.0 at aa 13-35, 73-95, 107-129, 139-161, 192-214 and 238-260 272560007544 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 42.2, E-value 7.4e-10 272560007545 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 272560007546 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560007547 Walker A/P-loop; other site 272560007548 ATP binding site [chemical binding]; other site 272560007549 Q-loop/lid; other site 272560007550 ABC transporter signature motif; other site 272560007551 Walker B; other site 272560007552 D-loop; other site 272560007553 H-loop/switch region; other site 272560007554 TOBE domain; Region: TOBE_2; pfam08402 272560007555 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 225.9, E-value 3.9e-65 272560007556 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007557 PS00211 ABC transporters family signature. 272560007558 Pfam match to entry PF03459 TOBE, TOBE domain , score 23.3, E-value 3e-06 272560007559 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560007560 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560007561 DNA-binding site [nucleotide binding]; DNA binding site 272560007562 FCD domain; Region: FCD; pfam07729 272560007563 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 50.4, E-value 2.5e-12 272560007564 PS00043 Bacterial regulatory proteins, gntR family signature. 272560007565 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 272560007566 tetramerization interface [polypeptide binding]; other site 272560007567 NAD(P) binding site [chemical binding]; other site 272560007568 catalytic residues [active] 272560007569 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 686.0, E-value 1.2e-203 272560007570 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560007571 PS00070 Aldehyde dehydrogenases cysteine active site. 272560007572 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560007573 trimer interface [polypeptide binding]; other site 272560007574 eyelet of channel; other site 272560007575 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -54.3, E-value 0.00041 272560007576 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 272560007577 HTH-like domain; Region: HTH_21; pfam13276 272560007578 Integrase core domain; Region: rve; pfam00665 272560007579 Integrase core domain; Region: rve_3; pfam13683 272560007580 Pfam match to entry PF00665 rve, Integrase core domain , score 148.5, E-value 7.5e-42 272560007581 Transposase; Region: HTH_Tnp_1; pfam01527 272560007582 Pfam match to entry PF01527 Transposase_8, Transposase , score 134.4, E-value 1.3e-37 272560007583 H-NS histone family; Region: Histone_HNS; pfam00816 272560007584 Chorismate mutase type II; Region: CM_2; cl00693 272560007585 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560007586 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 272560007587 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560007588 ligand binding site [chemical binding]; other site 272560007589 1 probable transmembrane helix predicted for BPSL1659 by TMHMM2.0 at aa 12-34 272560007590 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560007591 Pfam match to entry PF00691 OmpA, OmpA family , score 48.9, E-value 7.6e-12 272560007592 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 272560007593 Outer membrane efflux protein; Region: OEP; pfam02321 272560007594 Outer membrane efflux protein; Region: OEP; pfam02321 272560007595 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 52.8, E-value 4.9e-13 272560007596 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 13.1, E-value 0.00021 272560007597 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007598 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007599 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007600 Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753 272560007601 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007602 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007603 Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753 272560007604 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007605 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007606 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007607 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007608 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007609 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007610 Bacterial Ig-like domain (group 3); Region: Big_3_4; pfam13754 272560007611 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella; Region: VCBS; pfam13517 272560007612 Pfam match to entry PF00353 hemolysinCabind, Hemolysin-type calcium-binding repeat (2 copies) , score 24.5, E-value 0.00016 272560007613 PS00330 Hemolysin-type calcium-binding region signature. 272560007614 Pfam match to entry PF00353 hemolysinCabind, Hemolysin-type calcium-binding repeat (2 copies) , score 15.5, E-value 0.081 272560007615 Sulfotransferase family; Region: Sulfotransfer_3; pfam13469 272560007616 Pfam match to entry PF00685 Sulfotransfer, Sulfotransferase , score -92.1, E-value 0.044 272560007617 type I secretion system ATPase, LssB family; Region: type_I_sec_LssB; TIGR03375 272560007618 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560007619 ATP-binding cassette domain of bacteriocin exporters, subfamily C; Region: ABCC_bacteriocin_exporters; cd03245 272560007620 Walker A/P-loop; other site 272560007621 ATP binding site [chemical binding]; other site 272560007622 Q-loop/lid; other site 272560007623 ABC transporter signature motif; other site 272560007624 Walker B; other site 272560007625 D-loop; other site 272560007626 H-loop/switch region; other site 272560007627 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 43.0, E-value 4.3e-10 272560007628 5 probable transmembrane helices predicted for BPSL1664 by TMHMM2.0 at aa 206-228, 238-260, 315-337, 342-360 and 427-449 272560007629 PS00012 Phosphopantetheine attachment site. 272560007630 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 167.2, E-value 1.8e-47 272560007631 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007632 PS00136 Serine proteases, subtilase, aspartic acid active site. 272560007633 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 272560007634 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560007635 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560007636 1 probable transmembrane helix predicted for BPSL1665 by TMHMM2.0 at aa 58-80 272560007637 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 50.1, E-value 3.1e-12 272560007638 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007639 PS00543 HlyD family secretion proteins signature. 272560007640 Methyltransferase domain; Region: Methyltransf_23; pfam13489 272560007641 TPR repeat; Region: TPR_11; pfam13414 272560007642 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560007643 binding surface 272560007644 TPR motif; other site 272560007645 Tetratricopeptide repeat; Region: TPR_19; pfam14559 272560007646 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560007647 TPR repeat; Region: TPR_11; pfam13414 272560007648 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560007649 binding surface 272560007650 TPR motif; other site 272560007651 TPR repeat; Region: TPR_11; pfam13414 272560007652 TPR repeat; Region: TPR_11; pfam13414 272560007653 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560007654 TPR motif; other site 272560007655 binding surface 272560007656 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560007657 ADP-heptose:LPS heptosyl transferase I; Provisional; Region: PRK10964; cl15782 272560007658 Pfam match to entry PF00515 TPR, TPR Domain , score 37.2, E-value 2.5e-08 272560007659 Pfam match to entry PF00515 TPR, TPR Domain , score 22.1, E-value 0.00088 272560007660 Pfam match to entry PF00515 TPR, TPR Domain , score 3.3, E-value 1.3 272560007661 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007662 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007663 Pfam match to entry PF00515 TPR, TPR Domain , score 18.8, E-value 0.0085 272560007664 Pfam match to entry PF00515 TPR, TPR Domain , score 11.3, E-value 0.18 272560007665 Pfam match to entry PF00515 TPR, TPR Domain , score 22.4, E-value 0.00071 272560007666 Pfam match to entry PF00515 TPR, TPR Domain , score 33.5, E-value 3.2e-07 272560007667 Pfam match to entry PF00515 TPR, TPR Domain , score 21.3, E-value 0.0015 272560007668 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 21.6, E-value 4.8e-06 272560007669 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560007670 TPR motif; other site 272560007671 binding surface 272560007672 Tetratricopeptide repeat; Region: TPR_19; pfam14559 272560007673 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 20.9, E-value 7.3e-06 272560007674 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560007675 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 272560007676 ligand-binding site [chemical binding]; other site 272560007677 Pfam match to entry PF01583 APS_kinase, Adenylylsulfate kinase , score 312.5, E-value 3.3e-91 272560007678 PS00017 ATP/GTP-binding site motif A (P-loop). 272560007679 Similar to internal regions of Ralstonia solanacearum ISRso5-transposase TISRso5 SWALL:Q8Y371 (EMBL:AL646057) (363 aa) fasta scores: E(): 4.4e-07, 79.41% id in 34 aa, and to Agrobacterium tumefaciens transposase Orf1 SWALL:Q44454 (EMBL:Z18270) (366 aa) fasta scores: E(): 0.18, 54.54% id in 33 aa; transposase (fragment) 272560007680 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560007681 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560007682 active site 272560007683 phosphorylation site [posttranslational modification] 272560007684 intermolecular recognition site; other site 272560007685 dimerization interface [polypeptide binding]; other site 272560007686 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560007687 DNA binding site [nucleotide binding] 272560007688 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 105.4, E-value 7.4e-29 272560007689 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 58.3, E-value 1.1e-14 272560007690 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560007691 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560007692 Signal peptide predicted for BPSL1671 by SignalP 2.0 HMM (Signal peptide probabilty 0.986) with cleavage site probability 0.596 between residues 29 and 30; signal peptide 272560007693 Protein of unknown function (DUF2844); Region: DUF2844; pfam11005 272560007694 Protein of unknown function (DUF3443); Region: DUF3443; pfam11925 272560007695 Similar to the N-terminal regions of Bacteriophage phiE125 TnpB SWALL:Q8W6R2 (EMBL:AF447491) (284 aa) fasta scores: E(): 1.9e-30, 88.76% id in 89 aa, and Xanthomonas axonopodis transposase xac2432 SWALL:AAM37283 (EMBL:AE011880) (301 aa) fasta scores: E(): 3.4e-15, 56.18% id in 89 aa; tranposase (fragment) 272560007696 Signal peptide predicted for BPSL1674 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.890 between residues 18 and 19; signal peptide 272560007697 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560007698 trimer interface [polypeptide binding]; other site 272560007699 eyelet of channel; other site 272560007700 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -69.2, E-value 0.0016 272560007701 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560007702 Signal peptide predicted for BPSL1676 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 22 and 23; signal peptide 272560007703 Aromatic amino acid lyase; Region: Lyase_aromatic; pfam00221 272560007704 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 272560007705 active sites [active] 272560007706 tetramer interface [polypeptide binding]; other site 272560007707 Pfam match to entry PF00221 PAL, Phenylalanine and histidine ammonia-lyase , score 44.4, E-value 5.9e-18 272560007708 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560007709 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560007710 putative substrate translocation pore; other site 272560007711 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 158.4, E-value 8.2e-45 272560007712 12 probable transmembrane helices predicted for BPSL1677 by TMHMM2.0 at aa 21-38, 53-75, 82-104, 119-138, 151-173, 183-202, 240-262, 277-299, 306-326, 336-358, 371-393 and 403-422 272560007713 PS00216 Sugar transport proteins signature 1. 272560007714 PS00217 Sugar transport proteins signature 2. 272560007715 urocanate hydratase; Provisional; Region: PRK05414 272560007716 Pfam match to entry PF01175 Urocanase, Urocanase , score 763.9, E-value 4.2e-227 272560007717 Protein of unknown function (DUF917); Region: DUF917; pfam06032 272560007718 DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013 272560007719 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560007720 The C-terminal substrate-domain of LysR-type transcriptional regulators involved in the catabolism of opines and that of related regulators, contains the type 2 periplasmic binding fold; Region: PBP2_LysR_opines_like; cd08415 272560007721 putative dimerization interface [polypeptide binding]; other site 272560007722 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 166.2, E-value 3.6e-47 272560007723 PS00847 MCM family signature. 272560007724 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 78.6, E-value 8.3e-21 272560007725 Predicted helix-turn-helix motif with score 1926.000, SD 5.75 at aa 18-39, sequence GSISGAAKLLHVSQPAVSRLIS 272560007726 allantoinase; Provisional; Region: PRK06189 272560007727 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560007728 active site 272560007729 Pfam match to entry PF00744 Dihydroorotase, Dihydroorotase-like , score 66.6, E-value 3.5e-17 272560007730 allantoate amidohydrolase; Reviewed; Region: PRK12890 272560007731 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 272560007732 active site 272560007733 metal binding site [ion binding]; metal-binding site 272560007734 dimer interface [polypeptide binding]; other site 272560007735 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 20.8, E-value 3.8e-08 272560007736 Similar to the C-terminal regions of Mycobacterium tuberculosis hypothetical 23.8 kDa protein rv1674c or mtv047.09c or mt1712 SWALL:O53921 (EMBL:AL022002) (218 aa) fasta scores: E(): 3.8e-21, 59.81% id in 107 aa, and Mycobacterium tuberculosis hypothetical protein rv0324 or mt0339 or mtcy63.29 SWALL:O08446 (EMBL:Z96800) (226 aa) fasta scores: E(): 1.9e-17, 51.92% id in 104 aa;conserved hypothetical protein (fragment) 272560007737 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 61.9, E-value 8.7e-16 272560007738 PS00380 Rhodanese signature 1. 272560007739 Similar to the C-terminal regions of Shigella sonnei transposase for insertion sequence element IS629 SWALL:T629_SHISO (SWALL:P16942) (296 aa) fasta scores: E(): 5.2e-31, 60.26% id in 151 aa, and bacteriophage phiE125 hypothetical protein TnpB SWALL:Q8W6R2 (EMBL:AF447491) (284 aa) fasta scores: E(): 2.3e-50, 85.52% id in 152 aa; transposase (fragment) 272560007740 Pfam match to entry PF00665 rve, Integrase core domain , score 42.4, E-value 3.1e-12 272560007741 Pfam match to entry PF00665 rve, Integrase core domain , score 21.8, E-value 2.8e-06 272560007742 Gene remnant, similar to internal regions of Rhizobium meliloti transposase for insertion sequence element ISRm3 SWALL:TRA3_RHIME (SWALL:P80011) (400 aa) fasta scores: E(): 6.5e-09, 39.47% id in 114 aa, and Ralstonia solanacearum ISRso7-transposase rsp0478 or rs00356 or rsc0252 or rs00687 SWALL:Q8XEN1 (EMBL:AL646078) (416 aa) fasta scores: E(): 3.8e-11, 55.88% id in 68 aa; transposase (fragment) 272560007743 RNA polymerase sigma factor; Provisional; Region: PRK12536 272560007744 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560007745 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 272560007746 DNA binding residues [nucleotide binding] 272560007747 Protein of unknown function (DUF1109); Region: DUF1109; pfam06532 272560007748 6 probable transmembrane helices predicted for BPSL1687 by TMHMM2.0 at aa 27-49, 59-81, 94-116, 131-153, 160-179 and 189-211 272560007749 Protein of unknown function (DUF1109); Region: DUF1109; pfam06532 272560007750 5 probable transmembrane helices predicted for BPSL1688 by TMHMM2.0 at aa 48-70, 77-99, 114-136, 180-202 and 212-234 272560007751 Predicted membrane protein [Function unknown]; Region: COG2259 272560007752 2 probable transmembrane helices predicted for BPSL1689 by TMHMM2.0 at aa 100-122 and 137-156 272560007753 Uncharacterized protein conserved in bacteria (DUF2063); Region: DUF2063; pfam09836 272560007754 hypothetical protein; Provisional; Region: PRK05409 272560007755 Predicted integral membrane protein [Function unknown]; Region: COG5572 272560007756 Signal peptide predicted for BPSL1692 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 42 and 43; signal peptide 272560007757 Gene remnant, similar to internal regions of Ralstonia solanacearum ISRso14-transposase OrfB protein SWALL:Q8XF72 (EMBL:AL646083) (275 aa) fasta scores: E(): 1.1e-14, 44.64% id in 112 aa, and Pseudomonas aeruginosa hypothetical protein PA0987 SWALL:Q9I4Y2 (EMBL:AE004531) (280 aa) fasta scores: E(): 3.2e-15, 45.37% id in 119 aa;insertion element hypothetical protein (fragment) 272560007758 Pfam match to entry PF00665 rve, Integrase core domain , score 21.1, E-value 4.4e-06 272560007759 Gene remnant, similar to the C-terminal regions of Rhodobacter capsulatus hypothetical protein SWALL:O68059 (EMBL:AF010496) (440 aa) fasta scores: E(): 1.1e-27, 57.89% id in 133 aa, and Rhizobium etli hypothetical protein SWALL:AAM54798 (EMBL:U80928) (419 aa) fasta scores: E(): 9.8e-26, 58.53% id in 123 aa; transposase (fragment) 272560007760 Pfam match to entry PF02371 Transposase_20, Transposase IS116/IS110/IS902 family , score 56.9, E-value 2.2e-17 272560007761 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560007762 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560007763 DNA-binding site [nucleotide binding]; DNA binding site 272560007764 FCD domain; Region: FCD; pfam07729 272560007765 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 47.3, E-value 2.2e-11 272560007766 Predicted helix-turn-helix motif with score 1181.000, SD 3.21 at aa 33-54, sequence LSEAALSENLQISRNTLREIFR 272560007767 multiple promoter invertase; Provisional; Region: mpi; PRK13413 272560007768 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 272560007769 catalytic residues [active] 272560007770 catalytic nucleophile [active] 272560007771 Presynaptic Site I dimer interface [polypeptide binding]; other site 272560007772 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 272560007773 Synaptic Flat tetramer interface [polypeptide binding]; other site 272560007774 Synaptic Site I dimer interface [polypeptide binding]; other site 272560007775 DNA binding site [nucleotide binding] 272560007776 Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569 272560007777 DNA-binding interface [nucleotide binding]; DNA binding site 272560007778 Pfam match to entry PF00239 resolvase, Resolvase, N terminal domain , score 214.3, E-value 1.2e-61 272560007779 PS00397 Site-specific recombinases active site. 272560007780 PS00398 Site-specific recombinases signature 2. 272560007781 Predicted helix-turn-helix motif with score 2052.000, SD 6.18 at aa 169-190, sequence RSIAAVAKEFGVHPQTLRRLWA 272560007782 Similar to parts of Ralstonia solanacearum integrase/recombinase rsp0902 or rs01673 SWALL:Q8XRF2 (EMBL:AL646081) (566 aa) fasta scores: E(): 4.4e-54, 58.68% id in 259 aa. Note: Contains frameshifts at residues 46 and 116 and lack an appropriate start codon; recombinase (fragment) 272560007783 1 probable transmembrane helix predicted for BPSL1698 by TMHMM2.0 at aa 30-48 272560007784 Similar to the N-terminal regions of Ralstonia solanacearum lipoprotein rsp0564 or rs03914 SWALL:Q8XSB4 (EMBL:AL646079) (347 aa) fasta scores: E(): 2e-44, 65.04% id in 226 aa, and Ralstonia solanacearum hypothetical protein rsc2288 or rs01268 SWALL:Q8XX30 (EMBL:AL646069) (353 aa) fasta scores: E(): 4.4e-43, 62.44% id in 221 aa. Note: Contains an in-frame stop codon and various rframeshitfs at residues 30, 76, 126 and 188. Lacks an appropriate start codon;conserved hypothetical protein (fragment) 272560007785 multiple promoter invertase; Provisional; Region: mpi; PRK13413 272560007786 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 272560007787 catalytic residues [active] 272560007788 catalytic nucleophile [active] 272560007789 Presynaptic Site I dimer interface [polypeptide binding]; other site 272560007790 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 272560007791 Synaptic Flat tetramer interface [polypeptide binding]; other site 272560007792 Synaptic Site I dimer interface [polypeptide binding]; other site 272560007793 DNA binding site [nucleotide binding] 272560007794 Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cl17393 272560007795 DNA-binding interface [nucleotide binding]; DNA binding site 272560007796 Predicted helix-turn-helix motif with score 1788.000, SD 5.28 at aa 159-180, sequence QPIKCVAKQFNVHPRTLQRLQK 272560007797 Pfam match to entry PF00239 resolvase, Resolvase, N terminal domain , score 210.4, E-value 1.7e-60 272560007798 PS00398 Site-specific recombinases signature 2. 272560007799 PS00397 Site-specific recombinases active site. 272560007800 Gene remnant, similar to internal regions of Escherichia coli transposase InsD for insertion element IS2 SWALL:INSD_ECOLI (SWALL:P19777) (301 aa) fasta scores: E(): 2e-18, 51.93% id in 129 aa, and Ralstonia solanacearum ISRso10-transposase OrfB protein rsc1830 or rs04263 SWALL:Q8XYC8 (EMBL:AL646066) (282 aa) fasta scores: E(): 8e-32, 67.66% id in 133 aa;transposase (fragment) 272560007801 Transposase; Region: HTH_Tnp_1; cl17663 272560007802 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 272560007803 Pfam match to entry PF01527 Transposase_8, Transposase , score 88.6, E-value 7.9e-24 272560007804 Signal peptide predicted for BPSL1705 by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 1.000 between residues 23 and 24; signal peptide 272560007805 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560007806 trimer interface [polypeptide binding]; other site 272560007807 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560007808 trimer interface [polypeptide binding]; other site 272560007809 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007810 trimer interface [polypeptide binding]; other site 272560007811 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007812 trimer interface [polypeptide binding]; other site 272560007813 Protein of unknown function (DUF515); Region: DUF515; cl19548 272560007814 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560007815 trimer interface [polypeptide binding]; other site 272560007816 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560007817 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 43.7, E-value 2.6e-10 272560007818 H-NS histone family; Region: Histone_HNS; pfam00816 272560007819 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560007820 Signal peptide predicted for BPSL1707 by SignalP 2.0 HMM (Signal peptide probabilty 0.918) with cleavage site probability 0.560 between residues 26 and 27; signal peptide 272560007821 Glyoxal oxidase N-terminus; Region: Glyoxal_oxid_N; pfam07250 272560007822 Kelch domain; Region: Kelch; smart00612 272560007823 C-terminal Early set domain associated with the catalytic domain of galactose oxidase; Region: E_set_GO_C; cd02851 272560007824 SGNH_hydrolase subfamily, similar to Ruminococcus flavefaciens XynB. Most likely a secreted hydrolase with xylanase activity. SGNH hydrolases are a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from...; Region: XynB_like; cd01833 272560007825 active site 272560007826 catalytic triad [active] 272560007827 oxyanion hole [active] 272560007828 Pfam match to entry PF01344 Kelch, Kelch motif , score 20.6, E-value 0.0024 272560007829 Signal peptide predicted for BPSL1708 by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.577 between residues 29 and 30; signal peptide 272560007830 Pfam match to entry PF00036 efhand, EF hand , score 18.1, E-value 0.014 272560007831 Similar to parts of Caulobacter crescentus insertion sequence IS511 ORFA and ORFB genes, complete CDS cc2742 and cc0515 and cc2290 and cc2690 SWALL:Q45993 (EMBL:U39501) (308 aa) fasta scores: E(): 2.8e-10, 48.75% id in 80 aa, and of Rhizobium loti transposase for insertion sequence MSI240 SWALL:CAD31272 (EMBL:AL672114) (309 aa) fasta scores: E(): 1.8e-09, 46.25% id in 80 aa; insertion element (fragment) 272560007832 Partial CDS. Similar to parts of Streptomyces coelicolor non-ribosomal peptide synthase sco7682 or sc4c2.17 SWALL:Q9EWP5 (EMBL:AL450432) (2229 aa) fasta scores: E(): 1.5e-07, 44.66% id in 103 aa, and to Bacillus subtilis surfactin synthetase subunit 3 SrfAC or SrfA3 SWALL:SRF3_BACSU (SWALL:Q08787) (1274 aa) fasta scores: E(): 7.4e-06, 32.43% id in 148 aa, and to Pseudomonas aeruginosa pyochelin synthetase PchF or pa4225 SWALL:Q9HWG4 (EMBL:AE004839) (1809 aa) fasta scores: E(): 8.6e-06, 43.61% id in 94 aa; non-ribosomal peptide synthase (fragment) 272560007833 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 22.6, E-value 8e-06 272560007834 PS00012 Phosphopantetheine attachment site. 272560007835 1 probable transmembrane helix predicted for BPSL1709 by TMHMM2.0 at aa 105-127 272560007836 Signal peptide predicted for BPSL1710 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.394 between residues 30 and 31; signal peptide 272560007837 Protein related to penicillin acylase [General function prediction only]; Region: COG2366 272560007838 Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747 272560007839 active site 272560007840 Pfam match to entry PF01804 Penicil_amidase, Penicillin amidase , score 224.6, E-value 9.2e-65 272560007841 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560007842 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 272560007843 Pfam match to entry PF02543 CmcH_NodU, Carbamoyltransferase , score 351.7, E-value 5.2e-103 272560007844 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560007845 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07769 272560007846 acyl-activating enzyme (AAE) consensus motif; other site 272560007847 active site 272560007848 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007849 Condensation domain; Region: Condensation; cl19241 272560007850 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560007851 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560007852 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560007853 acyl-activating enzyme (AAE) consensus motif; other site 272560007854 AMP binding site [chemical binding]; other site 272560007855 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007856 Condensation domain; Region: Condensation; pfam00668 272560007857 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560007858 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560007859 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560007860 acyl-activating enzyme (AAE) consensus motif; other site 272560007861 AMP binding site [chemical binding]; other site 272560007862 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007863 Condensation domain; Region: Condensation; pfam00668 272560007864 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560007865 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560007866 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560007867 acyl-activating enzyme (AAE) consensus motif; other site 272560007868 AMP binding site [chemical binding]; other site 272560007869 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007870 Condensation domain; Region: Condensation; pfam00668 272560007871 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560007872 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560007873 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560007874 acyl-activating enzyme (AAE) consensus motif; other site 272560007875 AMP binding site [chemical binding]; other site 272560007876 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007877 Condensation domain; Region: Condensation; cl19241 272560007878 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560007879 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560007880 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560007881 acyl-activating enzyme (AAE) consensus motif; other site 272560007882 AMP binding site [chemical binding]; other site 272560007883 AMP-binding enzyme C-terminal domain; Region: AMP-binding_C; pfam13193 272560007884 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007885 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 67.7, E-value 1.6e-17 272560007886 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 475.5, E-value 2.8e-140 272560007887 PS00455 AMP-binding domain signature. 272560007888 Pfam match to entry PF00668 Condensation, Condensation domain , score 145.4, E-value 6.5e-41 272560007889 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 71.4, E-value 1.2e-18 272560007890 PS00012 Phosphopantetheine attachment site. 272560007891 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 425.9, E-value 2.4e-125 272560007892 PS00455 AMP-binding domain signature. 272560007893 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560007894 Pfam match to entry PF00668 Condensation, Condensation domain , score 287.3, E-value 1.3e-83 272560007895 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 71.1, E-value 1.5e-18 272560007896 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 406.2, E-value 2e-119 272560007897 PS00697 ATP-dependent DNA ligase AMP-binding site. 272560007898 PS00455 AMP-binding domain signature. 272560007899 Pfam match to entry PF00668 Condensation, Condensation domain , score 248.0, E-value 8.3e-72 272560007900 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 52.8, E-value 5e-13 272560007901 PS00012 Phosphopantetheine attachment site. 272560007902 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 437.7, E-value 6.7e-129 272560007903 PS00455 AMP-binding domain signature. 272560007904 Pfam match to entry PF00668 Condensation, Condensation domain , score 245.3, E-value 5.5e-71 272560007905 Predicted helix-turn-helix motif with score 1083.000, SD 2.88 at aa 2080-2101, sequence RNVRAVAARWGVTESTVYLAAY 272560007906 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 56.6, E-value 3.6e-14 272560007907 PS00012 Phosphopantetheine attachment site. 272560007908 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 435.2, E-value 3.8e-128 272560007909 Pfam match to entry PF00668 Condensation, Condensation domain , score 174.6, E-value 1.1e-49 272560007910 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 17.3, E-value 0.00024 272560007911 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560007912 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 287.9, E-value 8.3e-84 272560007913 PS00455 AMP-binding domain signature. 272560007914 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560007915 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560007916 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 41.2, E-value 1.5e-09 272560007917 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560007918 Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212 272560007919 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560007920 catalytic residue [active] 272560007921 argininosuccinate lyase; Provisional; Region: PRK02186 272560007922 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 272560007923 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 272560007924 active sites [active] 272560007925 tetramer interface [polypeptide binding]; other site 272560007926 Pfam match to entry PF00206 lyase_1, Lyase , score 68.5, E-value 9.3e-18 272560007927 PS00163 Fumarate lyases signature. 272560007928 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560007929 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 272560007930 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560007931 catalytic residue [active] 272560007932 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 28.4, E-value 1.4e-09 272560007933 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560007934 putative substrate translocation pore; other site 272560007935 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560007936 12 probable transmembrane helices predicted for BPSL1718 by TMHMM2.0 at aa 29-48, 58-80, 87-104, 108-129, 150-172, 177-199, 228-250, 265-282, 289-311, 321-340, 352-374 and 378-400 272560007937 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542 272560007938 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 272560007939 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein , score -24.2, E-value 0.0011 272560007940 PS00627 GHMP kinases ATP-binding domain. 272560007941 argininosuccinate lyase; Provisional; Region: PRK00855 272560007942 Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359 272560007943 active sites [active] 272560007944 tetramer interface [polypeptide binding]; other site 272560007945 Pfam match to entry PF00206 lyase_1, Lyase , score 276.7, E-value 2e-80 272560007946 PS00163 Fumarate lyases signature. 272560007947 Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate . In...; Region: Argininosuccinate_Synthase; cd01999 272560007948 ANP binding site [chemical binding]; other site 272560007949 Substrate Binding Site II [chemical binding]; other site 272560007950 Substrate Binding Site I [chemical binding]; other site 272560007951 Pfam match to entry PF00764 Arginosuc_synth, Arginosuccinate synthase , score 495.2, E-value 3.3e-146 272560007952 PS00565 Argininosuccinate synthase signature 2. 272560007953 PS00564 Argininosuccinate synthase signature 1. 272560007954 Formyltransferase, catalytic core domain; Region: FMT_core; cd08369 272560007955 active site 272560007956 substrate binding site [chemical binding]; other site 272560007957 cosubstrate binding site; other site 272560007958 catalytic site [active] 272560007959 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 12.9, E-value 1.6e-08 272560007960 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560007961 S-adenosylmethionine binding site [chemical binding]; other site 272560007962 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560007963 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079 272560007964 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560007965 homodimer interface [polypeptide binding]; other site 272560007966 catalytic residue [active] 272560007967 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 63.3, E-value 3.3e-16 272560007968 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560007969 Cupin-like domain; Region: Cupin_8; pfam13621 272560007970 Pfam match to entry PF02373 jmjC, jmjC domain , score 18.0, E-value 1.5e-05 272560007971 MbtH-like protein; Region: MbtH; cl01279 272560007972 Pfam match to entry PF03621 MbtH, MbtH-like protein , score 81.8, E-value 9.2e-22 272560007973 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560007974 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560007975 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560007976 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 30.0, E-value 3.5e-06 272560007977 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 53.8, E-value 2.5e-13 272560007978 Signal peptide predicted for BPSL1728 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 between residues 37 and 38; signal peptide 272560007979 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560007980 trimer interface [polypeptide binding]; other site 272560007981 eyelet of channel; other site 272560007982 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -48.6, E-value 0.00024 272560007983 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560007984 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560007985 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560007986 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 30.7, E-value 2.2e-06 272560007987 Predicted helix-turn-helix motif with score 1294.000, SD 3.59 at aa 183-204, sequence VSLAELASLAGVSRFQLLRGFA 272560007988 PS00041 Bacterial regulatory proteins, araC family signature. 272560007989 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 35.0, E-value 1.1e-07 272560007990 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560007991 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560007992 EamA-like transporter family; Region: EamA; pfam00892 272560007993 EamA-like transporter family; Region: EamA; pfam00892 272560007994 10 probable transmembrane helices predicted for BPSL1730 by TMHMM2.0 at aa 5-27, 37-55, 68-90, 100-117, 126-148, 153-172, 179-201, 216-238, 245-267 and 277-291 272560007995 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 65.0, E-value 1e-16 272560007996 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 61.2, E-value 1.4e-15 272560007997 CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732 272560007998 putative CheA interaction surface; other site 272560007999 Pfam match to entry PF01584 CheW, CheW-like domain , score 152.9, E-value 3.6e-43 272560008000 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560008001 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560008002 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560008003 dimer interface [polypeptide binding]; other site 272560008004 putative CheW interface [polypeptide binding]; other site 272560008005 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 336.0, E-value 2.8e-98 272560008006 2 probable transmembrane helices predicted for BPSL1732 by TMHMM2.0 at aa 13-35 and 194-216 272560008007 Protein of unknown function (DUF3562); Region: DUF3562; pfam12085 272560008008 AMP-binding domain protein; Validated; Region: PRK07529 272560008009 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560008010 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560008011 acyl-activating enzyme (AAE) consensus motif; other site 272560008012 acyl-activating enzyme (AAE) consensus motif; other site 272560008013 AMP binding site [chemical binding]; other site 272560008014 active site 272560008015 CoA binding site [chemical binding]; other site 272560008016 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 281.2, E-value 8.5e-82 272560008017 PS00455 AMP-binding domain signature. 272560008018 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560008019 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560008020 putative substrate translocation pore; other site 272560008021 11 probable transmembrane helices predicted for BPSL1735 by TMHMM2.0 at aa 38-60, 75-97, 131-153, 163-185, 198-217, 222-241, 254-276, 286-308, 328-350, 400-422 and 429-451 272560008022 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 18.2, E-value 1.1e-05 272560008023 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560008024 S-adenosylmethionine binding site [chemical binding]; other site 272560008025 Signal peptide predicted for BPSL1737 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.957 between residues 30 and 31; signal peptide 272560008026 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732 272560008027 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008028 dimer interface [polypeptide binding]; other site 272560008029 conserved gate region; other site 272560008030 putative PBP binding loops; other site 272560008031 ABC-ATPase subunit interface; other site 272560008032 11 probable transmembrane helices predicted for BPSL1738 by TMHMM2.0 at aa 13-30, 45-67, 74-96, 111-133, 140-162, 182-204, 217-239, 259-281, 302-321, 326-348 and 355-377 272560008033 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 65.5, E-value 7.4e-17 272560008034 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560008035 ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125 272560008036 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560008037 Walker A/P-loop; other site 272560008038 ATP binding site [chemical binding]; other site 272560008039 Q-loop/lid; other site 272560008040 ABC transporter signature motif; other site 272560008041 Walker B; other site 272560008042 D-loop; other site 272560008043 H-loop/switch region; other site 272560008044 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 234.0, E-value 1.4e-67 272560008045 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008046 PS00211 ABC transporters family signature. 272560008047 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008048 dimer interface [polypeptide binding]; other site 272560008049 conserved gate region; other site 272560008050 putative PBP binding loops; other site 272560008051 ABC-ATPase subunit interface; other site 272560008052 6 probable transmembrane helices predicted for BPSL1740 by TMHMM2.0 at aa 28-47, 76-98, 111-133, 138-160, 181-203 and 235-257 272560008053 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 56.4, E-value 4e-14 272560008054 arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810 272560008055 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -260.3, E-value 0.0032 272560008056 12 probable transmembrane helices predicted for BPSL1742 by TMHMM2.0 at aa 41-60, 70-92, 126-148, 158-175, 182-204, 231-253, 266-288, 314-336, 357-379, 389-411, 431-453 and 483-505 272560008057 arginine deiminase; Provisional; Region: PRK01388 272560008058 Pfam match to entry PF02274 Amidinotransf, Amidinotransferase , score 627.7, E-value 4.2e-186 272560008059 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560008060 ornithine carbamoyltransferase; Validated; Region: PRK02102 272560008061 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 272560008062 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 272560008063 Pfam match to entry PF02729 OTCace_N, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain , score 281.2, E-value 8.7e-82 272560008064 PS00097 Aspartate and ornithine carbamoyltransferases signature. 272560008065 Pfam match to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain , score 316.3, E-value 2.4e-92 272560008066 AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235 272560008067 putative substrate binding site [chemical binding]; other site 272560008068 nucleotide binding site [chemical binding]; other site 272560008069 nucleotide binding site [chemical binding]; other site 272560008070 homodimer interface [polypeptide binding]; other site 272560008071 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 314.9, E-value 6.2e-92 272560008072 short chain dehydrogenase; Provisional; Region: PRK09291 272560008073 17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374 272560008074 NADP binding site [chemical binding]; other site 272560008075 active site 272560008076 steroid binding site; other site 272560008077 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 167.8, E-value 1.2e-47 272560008078 PS00061 Short-chain dehydrogenases/reductases family signature. 272560008079 Domain of unknown function (DUF336); Region: DUF336; cl01249 272560008080 Pfam match to entry PF03928 DUF336, Domain of unknown function (DUF336) , score 118.7, E-value 7.2e-33 272560008081 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560008082 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560008083 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560008084 dimerization interface [polypeptide binding]; other site 272560008085 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 91.2, E-value 1.4e-24 272560008086 Predicted helix-turn-helix motif with score 1378.000, SD 3.88 at aa 21-42, sequence GNFTRAAAALGLTPAAVSLAIG 272560008087 PS00044 Bacterial regulatory proteins, lysR family signature. 272560008088 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 135.8, E-value 5e-38 272560008089 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 272560008090 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 272560008091 C-terminal domain interface [polypeptide binding]; other site 272560008092 GSH binding site (G-site) [chemical binding]; other site 272560008093 dimer interface [polypeptide binding]; other site 272560008094 C-terminal, alpha helical domain of Ure2p and related Glutathione S-transferase-like proteins; Region: GST_C_Ure2p_like; cd03178 272560008095 dimer interface [polypeptide binding]; other site 272560008096 N-terminal domain interface [polypeptide binding]; other site 272560008097 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 55.9, E-value 5.8e-14 272560008098 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 40.1, E-value 3.3e-09 272560008099 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560008100 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560008101 Pfam match to entry PF01047 MarR, MarR family , score 52.0, E-value 8.4e-13 272560008102 Signal peptide predicted for BPSL1751 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.983 between residues 20 and 21; signal peptide 272560008103 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560008104 dimerization interface [polypeptide binding]; other site 272560008105 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560008106 ligand binding site [chemical binding]; other site 272560008107 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 23.6, E-value 1.7e-06 272560008108 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560008109 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 272560008110 Pfam match to entry PF01047 MarR, MarR family , score 96.6, E-value 3.2e-26 272560008111 Signal peptide predicted for BPSL1753 by SignalP 2.0 HMM (Signal peptide probabilty 0.984) with cleavage site probability 0.983 between residues 26 and 27; signal peptide 272560008112 putative cyanate transporter; Provisional; Region: cynX; PRK09705 272560008113 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560008114 putative substrate translocation pore; other site 272560008115 12 probable transmembrane helices predicted for BPSL1753 by TMHMM2.0 at aa 7-26, 46-68, 75-94, 99-121, 133-155, 159-181, 202-224, 239-261, 268-290, 294-316, 328-350 and 360-379 272560008116 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -117.3, E-value 0.001 272560008117 Signal peptide predicted for BPSL1754 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.668 between residues 29 and 30; signal peptide 272560008118 Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893 272560008119 Pfam match to entry PF02638 DUF187, Uncharacterized BCR, COG1649 , score 444.2, E-value 7.2e-131 272560008120 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008121 Pfam match to entry PF00041 fn3, Fibronectin type III domain , score 12.8, E-value 0.01 272560008122 Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641 272560008123 active site 272560008124 SAM binding site [chemical binding]; other site 272560008125 homodimer interface [polypeptide binding]; other site 272560008126 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 206.7, E-value 2.2e-59 272560008127 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 272560008128 cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057 272560008129 Pfam match to entry PF02571 CbiJ, Precorrin-6x reductase CbiJ/CobK , score 112.9, E-value 4e-31 272560008130 cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075 272560008131 Pfam match to entry PF01888 CbiD, CbiD , score 270.4, E-value 1.6e-78 272560008132 Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644 272560008133 active site 272560008134 putative homodimer interface [polypeptide binding]; other site 272560008135 SAM binding site [chemical binding]; other site 272560008136 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560008137 S-adenosylmethionine binding site [chemical binding]; other site 272560008138 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 49.3, E-value 5.5e-12 272560008139 PS00211 ABC transporters family signature. 272560008140 precorrin-3B synthase; Region: CobG; TIGR02435 272560008141 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560008142 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 44.3, E-value 1.8e-10 272560008143 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 54.9, E-value 1.1e-13 272560008144 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain , score 32.5, E-value 6.5e-07 272560008145 precorrin-8X methylmutase; Reviewed; Region: cobH; PRK08285 272560008146 Pfam match to entry PF02570 CbiC, Precorrin-8X methylmutase , score 229.1, E-value 4.2e-66 272560008147 Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645 272560008148 active site 272560008149 SAM binding site [chemical binding]; other site 272560008150 homodimer interface [polypeptide binding]; other site 272560008151 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 120.2, E-value 2.6e-33 272560008152 PS00840 Uroporphyrin-III C-methyltransferase signature 2. 272560008153 PS00215 Mitochondrial energy transfer proteins signature. 272560008154 Cobalamin biosynthesis protein CbiG [Coenzyme metabolism]; Region: CbiG; COG2073 272560008155 Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760 272560008156 Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646 272560008157 active site 272560008158 SAM binding site [chemical binding]; other site 272560008159 homodimer interface [polypeptide binding]; other site 272560008160 Pfam match to entry PF01890 CbiG, CbiG , score -81.9, E-value 0.0018 272560008161 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 132.1, E-value 6.8e-37 272560008162 Signal peptide predicted for BPSL1763 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.983 between residues 32 and 33; signal peptide 272560008163 PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain. Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543 272560008164 active site 272560008165 Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704 272560008166 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 272560008167 aromatic chitin/cellulose binding site residues [chemical binding]; other site 272560008168 Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215 272560008169 aromatic chitin/cellulose binding site residues [chemical binding]; other site 272560008170 Pfam match to entry PF00704 Glyco_hydro_18, Glycosyl hydrolases family 18 , score -12.2, E-value 0.00022 272560008171 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain , score 65.3, E-value 8.5e-17 272560008172 Pfam match to entry PF02839 CBM_5_12, Carbohydrate binding domain , score 65.9, E-value 5.6e-17 272560008173 Signal peptide predicted for BPSL1764 by SignalP 2.0 HMM (Signal peptide probabilty 0.807) with cleavage site probability 0.804 between residues 44 and 45; signal peptide 272560008174 Predicted esterase [General function prediction only]; Region: COG0400 272560008175 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560008176 Pfam match to entry PF02230 abhydrolase_2, Phospholipase/Carboxylesterase , score 200.3, E-value 2e-57 272560008177 Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057 272560008178 metal ion-dependent adhesion site (MIDAS); other site 272560008179 Mg-chelatase subunit ChlI [Coenzyme metabolism]; Region: ChlI; COG1239 272560008180 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560008181 Walker A motif; other site 272560008182 ATP binding site [chemical binding]; other site 272560008183 Walker B motif; other site 272560008184 arginine finger; other site 272560008185 Immediate early response protein (IER); Region: IER; pfam05760 272560008186 Pfam match to entry PF01078 Mg_chelatase, Magnesium chelatase, subunit ChlI , score 283.7, E-value 1.6e-82 272560008187 cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989 272560008188 CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150 272560008189 Pfam match to entry PF02514 cobN-Mg_chel, CobN/Magnesium Chelatase , score 1238.2, E-value 0 272560008190 cobalamin biosynthesis protein CobW; Region: CobW; TIGR02475 272560008191 CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492 272560008192 Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683 272560008193 Pfam match to entry PF02492 cobW, Cobalamin synthesis protein/P47K , score 485.4, E-value 3e-143 272560008194 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008195 High-affinity nickel permease [Inorganic ion transport and metabolism]; Region: HoxN; COG3376 272560008196 8 probable transmembrane helices predicted for BPSL1770 by TMHMM2.0 at aa 43-65, 70-87, 110-132, 152-174, 209-231, 251-270, 298-320 and 340-362 272560008197 Pfam match to entry PF03824 NicO, High-affinity nickel-transport protein , score 543.2, E-value 1.2e-160 272560008198 cobalamin biosynthesis protein CbiG; Provisional; Region: PRK07027 272560008199 Pfam match to entry PF01890 CbiG, CbiG , score 33.5, E-value 8.4e-10 272560008200 Pfam match to entry PF01890 CbiG, CbiG , score 27.8, E-value 3.4e-08 272560008201 ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109 272560008202 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561 272560008203 homodimer interface [polypeptide binding]; other site 272560008204 Walker A motif; other site 272560008205 ATP binding site [chemical binding]; other site 272560008206 hydroxycobalamin binding site [chemical binding]; other site 272560008207 Walker B motif; other site 272560008208 Pfam match to entry PF02572 CobA_CobO_BtuR, ATP:corrinoid adenosyltransferase BtuR/CobO/CobP , score 306.5, E-value 2.1e-89 272560008209 cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077 272560008210 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560008211 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 272560008212 conserved cys residue [active] 272560008213 Pfam match to entry PF01656 CbiA, Cobyrinic acid a,c-diamide synthase , score 65.4, E-value 7.8e-17 272560008214 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008215 Formyltransferase, catalytic core domain; Region: FMT_core; cl00395 272560008216 active site 272560008217 cosubstrate binding site; other site 272560008218 substrate binding site [chemical binding]; other site 272560008219 catalytic site [active] 272560008220 Signal peptide predicted for BPSL1775 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.764 between residues 45 and 46; signal peptide 272560008221 ferrichrome outer membrane transporter; Provisional; Region: PRK10044 272560008222 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560008223 N-terminal plug; other site 272560008224 ligand-binding site [chemical binding]; other site 272560008225 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 73.8, E-value 2.4e-19 272560008226 L-lysine 6-monooxygenase (NADPH-requiring); Region: K_oxygenase; pfam13434 272560008227 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560008228 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560008229 Condensation domain; Region: Condensation; cl19241 272560008230 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560008231 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560008232 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560008233 acyl-activating enzyme (AAE) consensus motif; other site 272560008234 AMP binding site [chemical binding]; other site 272560008235 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560008236 Condensation domain; Region: Condensation; cl19241 272560008237 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560008238 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560008239 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 10.6, E-value 0.017 272560008240 Pfam match to entry PF00668 Condensation, Condensation domain , score 149.4, E-value 4.1e-42 272560008241 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 68.0, E-value 1.3e-17 272560008242 PS00012 Phosphopantetheine attachment site. 272560008243 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 433.7, E-value 1.1e-127 272560008244 PS00455 AMP-binding domain signature. 272560008245 Pfam match to entry PF00668 Condensation, Condensation domain , score 212.4, E-value 4.4e-61 272560008246 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560008247 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560008248 acyl-activating enzyme (AAE) consensus motif; other site 272560008249 AMP binding site [chemical binding]; other site 272560008250 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560008251 Condensation domain; Region: Condensation; pfam00668 272560008252 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560008253 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560008254 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560008255 acyl-activating enzyme (AAE) consensus motif; other site 272560008256 AMP binding site [chemical binding]; other site 272560008257 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560008258 Condensation domain; Region: Condensation; cl19241 272560008259 non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261 272560008260 Condensation domain; Region: Condensation; pfam00668 272560008261 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560008262 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560008263 acyl-activating enzyme (AAE) consensus motif; other site 272560008264 AMP binding site [chemical binding]; other site 272560008265 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 46.9, E-value 3e-11 272560008266 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 525.1, E-value 3.3e-155 272560008267 PS00455 AMP-binding domain signature. 272560008268 Pfam match to entry PF00668 Condensation, Condensation domain , score 200.5, E-value 1.7e-57 272560008269 Pfam match to entry PF00668 Condensation, Condensation domain , score 106.8, E-value 2.8e-29 272560008270 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 68.8, E-value 7.2e-18 272560008271 PS00012 Phosphopantetheine attachment site. 272560008272 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 436.5, E-value 1.5e-128 272560008273 PS00455 AMP-binding domain signature. 272560008274 Pfam match to entry PF00668 Condensation, Condensation domain , score 254.2, E-value 1.1e-73 272560008275 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 22.8, E-value 7.3e-06 272560008276 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 428.3, E-value 4.6e-126 272560008277 PS00455 AMP-binding domain signature. 272560008278 cyclic peptide transporter; Region: cyc_pep_trnsptr; TIGR01194 272560008279 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 272560008280 Walker A/P-loop; other site 272560008281 ATP binding site [chemical binding]; other site 272560008282 Q-loop/lid; other site 272560008283 ABC transporter signature motif; other site 272560008284 Walker B; other site 272560008285 D-loop; other site 272560008286 H-loop/switch region; other site 272560008287 6 probable transmembrane helices predicted for BPSL1779 by TMHMM2.0 at aa 37-59, 74-96, 141-163, 167-189, 255-277 and 287-309 272560008288 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 138.3, E-value 9.2e-39 272560008289 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008290 Domain of unknown function (DUF1993); Region: DUF1993; pfam09351 272560008291 Fe3+-siderophore binding domain FhuD. These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146 272560008292 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 272560008293 siderophore binding site; other site 272560008294 Pfam match to entry PF01497 Peripla_BP_2, Periplasmic binding protein , score 74.0, E-value 2e-19 272560008295 1 probable transmembrane helix predicted for BPSL1781 by TMHMM2.0 at aa 66-88 272560008296 siderophore-iron reductase FhuF; Region: Fe_III_red_FhuF; TIGR03951 272560008297 Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276 272560008298 FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575 272560008299 1 probable transmembrane helix predicted for BPSL1782 by TMHMM2.0 at aa 87-104 272560008300 iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577 272560008301 FecCD transport family; Region: FecCD; pfam01032 272560008302 ABC-ATPase subunit interface; other site 272560008303 dimer interface [polypeptide binding]; other site 272560008304 putative PBP binding regions; other site 272560008305 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 272560008306 ABC-ATPase subunit interface; other site 272560008307 dimer interface [polypeptide binding]; other site 272560008308 putative PBP binding regions; other site 272560008309 18 probable transmembrane helices predicted for BPSL1783 by TMHMM2.0 at aa 29-51, 77-99, 112-134, 138-159, 166-188, 258-280, 293-313, 323-345, 375-397, 428-450, 463-485, 489-508, 515-537, 559-581, 594-616, 620-642, 649-671 and 676-698 272560008310 Pfam match to entry PF01032 FecCD, FecCD transport family , score 235.0, E-value 6.9e-68 272560008311 Pfam match to entry PF01032 FecCD, FecCD transport family , score 141.6, E-value 9.3e-40 272560008312 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 272560008313 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 272560008314 Walker A/P-loop; other site 272560008315 ATP binding site [chemical binding]; other site 272560008316 Q-loop/lid; other site 272560008317 ABC transporter signature motif; other site 272560008318 Walker B; other site 272560008319 D-loop; other site 272560008320 H-loop/switch region; other site 272560008321 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 191.0, E-value 1.2e-54 272560008322 PS00211 ABC transporters family signature. 272560008323 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008324 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560008325 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560008326 MbtH-like protein; Region: MbtH; cl01279 272560008327 Pfam match to entry PF03621 MbtH, MbtH-like protein , score 124.1, E-value 1.7e-34 272560008328 extracytoplasmic-function sigma-70 factor; Validated; Region: PRK07037 272560008329 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560008330 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 272560008331 DNA binding residues [nucleotide binding] 272560008332 Predicted helix-turn-helix motif with score 1268.000, SD 3.51 at aa 146-167, sequence ETLQSAARALNVSQTLVHFMVR 272560008333 short chain dehydrogenase; Provisional; Region: PRK07060 272560008334 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560008335 NAD(P) binding site [chemical binding]; other site 272560008336 active site 272560008337 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 216.0, E-value 3.6e-62 272560008338 PS00061 Short-chain dehydrogenases/reductases family signature. 272560008339 Pseudogene. Similar to Thermotoga maritima sugar kinase, FggY family tm0284 SWALL:Q9WYC0 (EMBL:AE001710) (506 aa) fasta scores: E(): 2.1e-90, 45.54% id in 505 aa, and to Yersinia pestis KIM xylulose kinase y2893 SWALL:AAM86444 (EMBL:AE013892) (517 aa) fasta scores: E(): 1.3e-38, 32.38% id in 528 aa. Contains a frameshift after residue 455; sugar kinase (pseudogene) 272560008340 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 115.8, E-value 5.3e-32 272560008341 PS00445 FGGY family of carbohydrate kinases signature 2. 272560008342 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 184.7, E-value 9.4e-53 272560008343 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560008344 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560008345 NAD(P) binding site [chemical binding]; other site 272560008346 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 232.4, E-value 4.2e-67 272560008347 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560008348 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560008349 TM-ABC transporter signature motif; other site 272560008350 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -44.0, E-value 0.00011 272560008351 8 probable transmembrane helices predicted for BPSL1791 by TMHMM2.0 at aa 40-62, 74-93, 108-130, 137-159, 186-208, 238-260, 275-305 and 312-334 272560008352 Signal peptide predicted for BPSL1793 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 35 and 36; signal peptide 272560008353 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321 272560008354 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560008355 putative ligand binding site [chemical binding]; other site 272560008356 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -29.7, E-value 0.0012 272560008357 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560008358 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560008359 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560008360 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 37.1, E-value 2.7e-08 272560008361 PS00041 Bacterial regulatory proteins, araC family signature. 272560008362 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 22.0, E-value 0.00092 272560008363 Predicted helix-turn-helix motif with score 1656.000, SD 4.83 at aa 207-228, sequence LRETDLARLAGQSVSAFSHYFR 272560008364 Transglutaminase-like superfamily; Region: Transglut_core3; pfam13471 272560008365 Glutamine amidotransferases class-II (GATase). The glutaminase domain catalyzes an amide nitrogen transfer from glutamine to the appropriate substrate. In this process, glutamine is hydrolyzed to glutamic acid and ammonia. This domain is related to...; Region: Gn_AT_II; cl00319 272560008366 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 272560008367 Ligand Binding Site [chemical binding]; other site 272560008368 Molecular Tunnel; other site 272560008369 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 272560008370 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560008371 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560008372 Walker A/P-loop; other site 272560008373 ATP binding site [chemical binding]; other site 272560008374 Q-loop/lid; other site 272560008375 ABC transporter signature motif; other site 272560008376 Walker B; other site 272560008377 D-loop; other site 272560008378 H-loop/switch region; other site 272560008379 6 probable transmembrane helices predicted for BPSL1797 by TMHMM2.0 at aa 26-48, 68-90, 142-164, 168-187, 248-270 and 285-307 272560008380 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score -32.7, E-value 0.0086 272560008381 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 132.6, E-value 4.5e-37 272560008382 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008383 Signal peptide predicted for BPSL1798 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.555 between residues 33 and 34; signal peptide 272560008384 Fimbrial protein; Region: Fimbrial; pfam00419 272560008385 Signal peptide predicted for BPSL1799 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 31 and 32; signal peptide 272560008386 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 272560008387 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560008388 Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753 272560008389 Pfam match to entry PF02753 pili_assembly_C, Gram-negative pili assembly chaperone, C-terminal domain , score 24.9, E-value 3e-07 272560008390 Pfam match to entry PF00345 pili_assembly, Gram-negative pili assembly chaperone, N-terminal domain , score 164.4, E-value 1.3e-46 272560008391 PS00635 Gram-negative pili assembly chaperone signature. 272560008392 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560008393 Signal peptide predicted for BPSL1800 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.738 between residues 21 and 22; signal peptide 272560008394 PapC N-terminal domain; Region: PapC_N; pfam13954 272560008395 Outer membrane usher protein; Region: Usher; pfam00577 272560008396 PapC C-terminal domain; Region: PapC_C; pfam13953 272560008397 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score 717.8, E-value 3.2e-213 272560008398 PS01151 Fimbrial biogenesis outer membrane usher protein signature. 272560008399 Fimbrial protein; Region: Fimbrial; cl01416 272560008400 Signal peptide predicted for BPSL1801 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 60 and 61; signal peptide 272560008401 Pfam match to entry PF00419 Fimbrial, Fimbrial protein , score 137.0, E-value 2.2e-38 272560008402 Signal peptide predicted for BPSL1802 by SignalP 2.0 HMM (Signal peptide probabilty 0.760) with cleavage site probability 0.305 between residues 43 and 44; signal peptide 272560008403 copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837 272560008404 Outer membrane efflux protein; Region: OEP; pfam02321 272560008405 Outer membrane efflux protein; Region: OEP; pfam02321 272560008406 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 155.9, E-value 4.5e-44 272560008407 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 129.7, E-value 3.4e-36 272560008408 multidrug efflux protein; Reviewed; Region: PRK09577 272560008409 MMPL family; Region: MMPL; cl14618 272560008410 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1543.0, E-value 0 272560008411 12 probable transmembrane helices predicted for BPSL1803 by TMHMM2.0 at aa 9-31, 339-358, 365-387, 391-413, 437-459, 469-491, 538-560, 864-886, 893-915, 920-942, 963-985 and 1000-1022 272560008412 Signal peptide predicted for BPSL1804 by SignalP 2.0 HMM (Signal peptide probabilty 0.981) with cleavage site probability 0.484 between residues 24 and 25; signal peptide 272560008413 periplasmic multidrug efflux lipoprotein precursor; Reviewed; Region: PRK09578 272560008414 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560008415 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560008416 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 241.5, E-value 7.6e-70 272560008417 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008418 DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668 272560008419 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560008420 MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361 272560008421 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 57.2, E-value 2.3e-14 272560008422 Predicted helix-turn-helix motif with score 1624.000, SD 4.72 at aa 32-53, sequence TAMADIAEAAGMSRGAVYGHFN 272560008423 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 272560008424 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560008425 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 127.2, E-value 2e-35 272560008426 ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765 272560008427 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008428 dimer interface [polypeptide binding]; other site 272560008429 conserved gate region; other site 272560008430 putative PBP binding loops; other site 272560008431 ABC-ATPase subunit interface; other site 272560008432 4 probable transmembrane helices predicted for BPSL1807 by TMHMM2.0 at aa 32-54, 61-83, 93-115 and 197-216 272560008433 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 62.2, E-value 7.1e-16 272560008434 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560008435 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 272560008436 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008437 dimer interface [polypeptide binding]; other site 272560008438 conserved gate region; other site 272560008439 putative PBP binding loops; other site 272560008440 ABC-ATPase subunit interface; other site 272560008441 3 probable transmembrane helices predicted for BPSL1808 by TMHMM2.0 at aa 15-37, 58-80 and 205-227 272560008442 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 46.8, E-value 3.1e-11 272560008443 Signal peptide predicted for BPSL1809 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.820 between residues 24 and 25; signal peptide 272560008444 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560008445 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560008446 substrate binding pocket [chemical binding]; other site 272560008447 membrane-bound complex binding site; other site 272560008448 hinge residues; other site 272560008449 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 251.6, E-value 7.2e-73 272560008450 1 probable transmembrane helix predicted for BPSL1810 by TMHMM2.0 at aa 2-19 272560008451 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 272560008452 TadE-like protein; Region: TadE; pfam07811 272560008453 2 probable transmembrane helices predicted for BPSL1811 by TMHMM2.0 at aa 13-35 and 117-139 272560008454 tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795 272560008455 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560008456 TPR motif; other site 272560008457 binding surface 272560008458 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560008459 binding surface 272560008460 TPR motif; other site 272560008461 1 probable transmembrane helix predicted for BPSL1812 by TMHMM2.0 at aa 13-35 272560008462 Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064 272560008463 4 probable transmembrane helices predicted for BPSL1813 by TMHMM2.0 at aa 5-24, 99-121, 136-158 and 289-311 272560008464 Type II secretion system (T2SS), protein F; Region: T2SF; cl19503 272560008465 5 probable transmembrane helices predicted for BPSL1814 by TMHMM2.0 at aa 4-26, 101-123, 128-147, 270-289 and 304-321 272560008466 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 272560008467 ATP binding site [chemical binding]; other site 272560008468 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 272560008469 Walker A motif; other site 272560008470 hexamer interface [polypeptide binding]; other site 272560008471 Walker B motif; other site 272560008472 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score -27.1, E-value 3e-08 272560008473 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008474 PS00227 Tubulin subunits alpha, beta, and gamma signature. 272560008475 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078 272560008476 AAA domain; Region: AAA_31; pfam13614 272560008477 CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656 272560008478 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score -15.3, E-value 0.0081 272560008479 Predicted helix-turn-helix motif with score 1033.000, SD 2.71 at aa 83-104, sequence MPLSDLARLADVCDPSVNVIVI 272560008480 Signal peptide predicted for BPSL1817 by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.571 between residues 37 and 38; signal peptide 272560008481 Type IV pili component [Cell motility and secretion]; Region: COG5461; cl19894 272560008482 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008483 Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964 272560008484 Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629 272560008485 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560008486 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 230.1, E-value 2.1e-66 272560008487 Signal peptide predicted for BPSL1819 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.386 between residues 28 and 29; signal peptide 272560008488 Domains similar to fish antifreeze type III protein; Region: SAF; cl00555 272560008489 Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960 272560008490 5 probable transmembrane helices predicted for BPSL1820 by TMHMM2.0 at aa 7-29, 39-61, 66-88, 108-130 and 142-164 272560008491 Flp/Fap pilin component; Region: Flp_Fap; cl01585 272560008492 1 probable transmembrane helix predicted for BPSL1821 by TMHMM2.0 at aa 20-42 272560008493 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 272560008494 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008495 dimer interface [polypeptide binding]; other site 272560008496 conserved gate region; other site 272560008497 putative PBP binding loops; other site 272560008498 ABC-ATPase subunit interface; other site 272560008499 6 probable transmembrane helices predicted for BPSL1822 by TMHMM2.0 at aa 128-150, 160-182, 187-209, 229-251, 256-278 and 288-307 272560008500 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 21.2, E-value 0.0005 272560008501 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 272560008502 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 272560008503 Walker A/P-loop; other site 272560008504 ATP binding site [chemical binding]; other site 272560008505 Q-loop/lid; other site 272560008506 ABC transporter signature motif; other site 272560008507 Walker B; other site 272560008508 D-loop; other site 272560008509 H-loop/switch region; other site 272560008510 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 193.9, E-value 1.7e-55 272560008511 PS00211 ABC transporters family signature. 272560008512 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008513 Signal peptide predicted for BPSL1824 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.714 between residues 32 and 33; signal peptide 272560008514 NMT1-like family; Region: NMT1_2; pfam13379 272560008515 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 272560008516 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 272560008517 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560008518 putative substrate translocation pore; other site 272560008519 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 232.5, E-value 4.1e-67 272560008520 12 probable transmembrane helices predicted for BPSL1825 by TMHMM2.0 at aa 20-39, 59-81, 93-115, 119-138, 158-180, 195-212, 242-264, 279-301, 308-330, 335-357, 370-392 and 402-419 272560008521 PS00217 Sugar transport proteins signature 2. 272560008522 SpoVR family protein; Provisional; Region: PRK11767 272560008523 hypothetical protein; Provisional; Region: PRK05325 272560008524 PrkA family serine protein kinase; Provisional; Region: PRK15455 272560008525 PrkA AAA domain; Region: AAA_PrkA; pfam08298 272560008526 Walker A motif; other site 272560008527 ATP binding site [chemical binding]; other site 272560008528 PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798 272560008529 PS00107 Protein kinases ATP-binding region signature. 272560008530 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008531 Signal peptide predicted for BPSL1829 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.702 between residues 45 and 46; signal peptide 272560008532 methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041 272560008533 Tar ligand binding domain homologue; Region: TarH; pfam02203 272560008534 dimer interface [polypeptide binding]; other site 272560008535 ligand binding site [chemical binding]; other site 272560008536 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560008537 dimerization interface [polypeptide binding]; other site 272560008538 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560008539 dimer interface [polypeptide binding]; other site 272560008540 putative CheW interface [polypeptide binding]; other site 272560008541 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 355.4, E-value 3.9e-104 272560008542 Pfam match to entry PF00672 HAMP, HAMP domain , score 41.8, E-value 1e-09 272560008543 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 272560008544 substrate binding site [chemical binding]; other site 272560008545 dimer interface [polypeptide binding]; other site 272560008546 ATP binding site [chemical binding]; other site 272560008547 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 262.6, E-value 3.4e-76 272560008548 PS00584 pfkB family of carbohydrate kinases signature 2. 272560008549 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008550 PS00583 pfkB family of carbohydrate kinases signature 1. 272560008551 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560008552 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560008553 DNA binding site [nucleotide binding] 272560008554 domain linker motif; other site 272560008555 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 272560008556 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 116.8, E-value 2.7e-32 272560008557 Pfam match to entry PF00356 lacI, Bacterial regulatory proteins, lacI family , score 39.1, E-value 6.4e-09 272560008558 Predicted helix-turn-helix motif with score 1728.000, SD 5.07 at aa 2-23, sequence ATIKDVAAIAGVSFTTVSHVVN 272560008559 PS00356 Bacterial regulatory proteins, lacI family signature. 272560008560 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560008561 TM-ABC transporter signature motif; other site 272560008562 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -38.2, E-value 5.9e-05 272560008563 PS00307 Legume lectins beta-chain signature. 272560008564 6 probable transmembrane helices predicted for BPSL1832 by TMHMM2.0 at aa 29-51, 80-102, 114-136, 179-201, 232-251 and 286-308 272560008565 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 272560008566 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560008567 Walker A/P-loop; other site 272560008568 ATP binding site [chemical binding]; other site 272560008569 Q-loop/lid; other site 272560008570 ABC transporter signature motif; other site 272560008571 Walker B; other site 272560008572 D-loop; other site 272560008573 H-loop/switch region; other site 272560008574 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560008575 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 62.6, E-value 5.5e-16 272560008576 PS00211 ABC transporters family signature. 272560008577 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 179.7, E-value 3.1e-51 272560008578 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008579 Signal peptide predicted for BPSL1834 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.347 between residues 29 and 30; signal peptide 272560008580 Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536 272560008581 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560008582 ligand binding site [chemical binding]; other site 272560008583 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 28.2, E-value 2.5e-07 272560008584 1 probable transmembrane helix predicted for BPSL1834 by TMHMM2.0 at aa 9-28 272560008585 transcriptional regulator CysB-like protein; Reviewed; Region: PRK12683 272560008586 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560008587 The C-terminal substrate domain of LysR-type transcriptional regulators CysB-like contains type 2 periplasmic binding fold; Region: PBP2_CysB_like; cd08413 272560008588 substrate binding site [chemical binding]; other site 272560008589 dimerization interface [polypeptide binding]; other site 272560008590 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 177.5, E-value 1.4e-50 272560008591 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 60.8, E-value 2e-15 272560008592 PS00044 Bacterial regulatory proteins, lysR family signature. 272560008593 Predicted helix-turn-helix motif with score 1606.000, SD 4.66 at aa 17-38, sequence MNLTEVANVLYTSQSGVSKQIK 272560008594 ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118 272560008595 ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296 272560008596 Walker A/P-loop; other site 272560008597 ATP binding site [chemical binding]; other site 272560008598 Q-loop/lid; other site 272560008599 ABC transporter signature motif; other site 272560008600 Walker B; other site 272560008601 D-loop; other site 272560008602 H-loop/switch region; other site 272560008603 TOBE-like domain; Region: TOBE_3; pfam12857 272560008604 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 239.5, E-value 3.1e-69 272560008605 PS00211 ABC transporters family signature. 272560008606 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008607 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008608 dimer interface [polypeptide binding]; other site 272560008609 conserved gate region; other site 272560008610 putative PBP binding loops; other site 272560008611 ABC-ATPase subunit interface; other site 272560008612 6 probable transmembrane helices predicted for BPSL1837 by TMHMM2.0 at aa 9-31, 59-81, 94-116, 129-151, 190-212 and 235-257 272560008613 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 37.0, E-value 2.7e-08 272560008614 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560008615 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560008616 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008617 dimer interface [polypeptide binding]; other site 272560008618 conserved gate region; other site 272560008619 putative PBP binding loops; other site 272560008620 ABC-ATPase subunit interface; other site 272560008621 6 probable transmembrane helices predicted for BPSL1838 by TMHMM2.0 at aa 21-43, 75-97, 110-132, 147-169, 199-221 and 253-275 272560008622 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 72.1, E-value 7.9e-19 272560008623 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560008624 Signal peptide predicted for BPSL1839 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.979 between residues 35 and 36; signal peptide 272560008625 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560008626 substrate binding pocket [chemical binding]; other site 272560008627 membrane-bound complex binding site; other site 272560008628 Pfam match to entry PF01100 Sulphate_bind, Prokaryotic sulphate- and thiosulphate-binding protein , score 635.4, E-value 2.1e-188 272560008629 PS00757 Prokaryotic sulfate-binding proteins signature 2. 272560008630 LexA repressor; Validated; Region: PRK00215 272560008631 LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726 272560008632 Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529 272560008633 Catalytic site [active] 272560008634 Pfam match to entry PF01726 LexA_DNA_bind, LexA DNA binding domain , score 123.6, E-value 2.5e-34 272560008635 Pfam match to entry PF00717 Peptidase_S24, Peptidase S24 , score 156.1, E-value 3.8e-44 272560008636 Protein of unknown function (DUF2939); Region: DUF2939; pfam11159 272560008637 2 probable transmembrane helices predicted for BPSL1842 by TMHMM2.0 at aa 15-37 and 87-109 272560008638 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560008639 Ligand Binding Site [chemical binding]; other site 272560008640 Pfam match to entry PF00582 Usp, Universal stress protein family , score 39.4, E-value 5.4e-09 272560008641 nodulation ABC transporter NodI; Provisional; Region: PRK13537 272560008642 ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263 272560008643 Walker A/P-loop; other site 272560008644 ATP binding site [chemical binding]; other site 272560008645 Q-loop/lid; other site 272560008646 ABC transporter signature motif; other site 272560008647 Walker B; other site 272560008648 D-loop; other site 272560008649 H-loop/switch region; other site 272560008650 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 233.4, E-value 2e-67 272560008651 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008652 PS00211 ABC transporters family signature. 272560008653 ABC-2 type transporter; Region: ABC2_membrane; cl17235 272560008654 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560008655 Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter , score -52.1, E-value 8.5e-05 272560008656 6 probable transmembrane helices predicted for BPSL1845 by TMHMM2.0 at aa 46-68, 78-100, 134-156, 166-188, 193-215 and 250-272 272560008657 Predicted permease; Region: DUF318; cl17795 272560008658 9 probable transmembrane helices predicted for BPSL1847 by TMHMM2.0 at aa 10-32, 81-103, 113-135, 147-169, 173-192, 236-255, 265-287, 292-314 and 329-351 272560008659 Pfam match to entry PF03773 DUF318, Predicted permease , score 146.6, E-value 2.8e-41 272560008660 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 272560008661 voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293 272560008662 active site 272560008663 catalytic tetrad [active] 272560008664 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase , score 171.6, E-value 8.6e-49 272560008665 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560008666 CoenzymeA binding site [chemical binding]; other site 272560008667 subunit interaction site [polypeptide binding]; other site 272560008668 PHB binding site; other site 272560008669 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 5.1, E-value 2.6e-05 272560008670 Predicted transcriptional regulators [Transcription]; Region: COG1733 272560008671 Pfam match to entry PF01638 DUF24, Transcriptional regulator , score 100.8, E-value 1.8e-27 272560008672 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 272560008673 Signal peptide predicted for BPSL1851 by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.508 between residues 35 and 36; signal peptide 272560008674 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 378.7, E-value 3.8e-111 272560008675 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008676 6 probable transmembrane helices predicted for BPSL1851 by TMHMM2.0 at aa 49-71, 84-106, 154-171, 192-214, 227-249 and 315-337 272560008677 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 272560008678 Dihydrouridine synthase (Dus); Region: Dus; pfam01207 272560008679 FMN binding site [chemical binding]; other site 272560008680 active site 272560008681 catalytic residues [active] 272560008682 substrate binding site [chemical binding]; other site 272560008683 Pfam match to entry PF01207 UPF0034, Uncharacterized protein family UPF0034 , score 333.7, E-value 1.3e-97 272560008684 PS01136 Uncharacterized protein family UPF0034 signature. 272560008685 Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585 272560008686 Pfam match to entry PF03459 TOBE, TOBE domain , score 52.0, E-value 8.6e-13 272560008687 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116 272560008688 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560008689 Walker A/P-loop; other site 272560008690 ATP binding site [chemical binding]; other site 272560008691 Q-loop/lid; other site 272560008692 ABC transporter signature motif; other site 272560008693 Walker B; other site 272560008694 D-loop; other site 272560008695 H-loop/switch region; other site 272560008696 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 187.5, E-value 1.4e-53 272560008697 PS00211 ABC transporters family signature. 272560008698 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008699 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 272560008700 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008701 dimer interface [polypeptide binding]; other site 272560008702 conserved gate region; other site 272560008703 putative PBP binding loops; other site 272560008704 ABC-ATPase subunit interface; other site 272560008705 5 probable transmembrane helices predicted for BPSL1857 by TMHMM2.0 at aa 78-100, 110-132, 139-158, 187-209 and 229-246 272560008706 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 40.8, E-value 2e-09 272560008707 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 272560008708 active site 272560008709 dimer interface [polypeptide binding]; other site 272560008710 non-prolyl cis peptide bond; other site 272560008711 insertion regions; other site 272560008712 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score -59.7, E-value 0.00019 272560008713 4 probable transmembrane helices predicted for BPSL1859 by TMHMM2.0 at aa 7-29, 56-78, 85-107 and 122-144 272560008714 3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617 272560008715 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560008716 substrate binding site [chemical binding]; other site 272560008717 oxyanion hole (OAH) forming residues; other site 272560008718 trimer interface [polypeptide binding]; other site 272560008719 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 272560008720 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 77.5, E-value 1.8e-20 272560008721 Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076 272560008722 4 probable transmembrane helices predicted for BPSL1861 by TMHMM2.0 at aa 5-22, 32-51, 58-80 and 84-106 272560008723 Pfam match to entry PF00893 DUF7, Integral membrane protein DUF7 , score 136.4, E-value 3.5e-38 272560008724 hypothetical protein; Provisional; Region: PRK02487 272560008725 Nudix N-terminal; Region: Nudix_N_2; pfam14803 272560008726 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_4; cd04511 272560008727 nudix motif; other site 272560008728 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 72.9, E-value 4.4e-19 272560008729 PS00893 mutT domain signature. 272560008730 leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301 272560008731 Pfam match to entry PF03588 Leu_Phe_trans, Leucyl/phenylalanyl-tRNA protein transferase , score 285.1, E-value 6e-83 272560008732 arginyl-tRNA-protein transferase; Provisional; Region: PRK01305 272560008733 Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376 272560008734 Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377 272560008735 dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286 272560008736 Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738 272560008737 quinone interaction residues [chemical binding]; other site 272560008738 active site 272560008739 catalytic residues [active] 272560008740 FMN binding site [chemical binding]; other site 272560008741 substrate binding site [chemical binding]; other site 272560008742 Pfam match to entry PF01180 DHOdehase, Dihydroorotate dehydrogenase , score 457.9, E-value 5.5e-135 272560008743 PS00911 Dihydroorotate dehydrogenase signature 1. 272560008744 PS00912 Dihydroorotate dehydrogenase signature 2. 272560008745 cystine transporter subunit; Provisional; Region: PRK11260 272560008746 Signal peptide predicted for BPSL1867 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.996 between residues 46 and 47; signal peptide 272560008747 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560008748 substrate binding pocket [chemical binding]; other site 272560008749 membrane-bound complex binding site; other site 272560008750 hinge residues; other site 272560008751 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 281.6, E-value 6.5e-82 272560008752 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560008753 ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765 272560008754 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560008755 dimer interface [polypeptide binding]; other site 272560008756 conserved gate region; other site 272560008757 putative PBP binding loops; other site 272560008758 ABC-ATPase subunit interface; other site 272560008759 3 probable transmembrane helices predicted for BPSL1868 by TMHMM2.0 at aa 45-67, 79-101 and 198-220 272560008760 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 63.1, E-value 4e-16 272560008761 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 272560008762 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 272560008763 Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase, NAD-binding Rossmann fold , score 99.7, E-value 3.7e-27 272560008764 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560008765 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 272560008766 DNA-binding site [nucleotide binding]; DNA binding site 272560008767 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 272560008768 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 31.8, E-value 1.1e-06 272560008769 RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398 272560008770 tetramer (dimer of dimers) interface [polypeptide binding]; other site 272560008771 active site 272560008772 dimer interface [polypeptide binding]; other site 272560008773 PS00063 Aldo/keto reductase active site signature. 272560008774 Signal peptide predicted for BPSL1872 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.588 between residues 19 and 20; signal peptide 272560008775 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 272560008776 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 272560008777 amidase catalytic site [active] 272560008778 Zn binding residues [ion binding]; other site 272560008779 substrate binding site [chemical binding]; other site 272560008780 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 272560008781 Pfam match to entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase , score 152.2, E-value 5.9e-43 272560008782 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008783 RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032 272560008784 23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181 272560008785 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 272560008786 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase , score 193.5, E-value 2.2e-55 272560008787 ribonuclease R; Region: RNase_R; TIGR02063 272560008788 Ribonuclease B OB domain; Region: OB_RNB; pfam08206 272560008789 This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955 272560008790 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560008791 S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471 272560008792 RNA binding site [nucleotide binding]; other site 272560008793 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 56.8, E-value 3.2e-14 272560008794 PS01175 Ribonuclease II family signature. 272560008795 Pfam match to entry PF00773 RNB, RNB-like protein , score 430.5, E-value 9.7e-127 272560008796 Signal peptide predicted for BPSL1875 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.547 between residues 23 and 24; signal peptide 272560008797 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560008798 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560008799 dimerization interface [polypeptide binding]; other site 272560008800 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560008801 dimer interface [polypeptide binding]; other site 272560008802 putative CheW interface [polypeptide binding]; other site 272560008803 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 285.6, E-value 4.2e-83 272560008804 Pfam match to entry PF00672 HAMP, HAMP domain , score 29.5, E-value 4.9e-06 272560008805 2 probable transmembrane helices predicted for BPSL1875 by TMHMM2.0 at aa 15-34 and 230-252 272560008806 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560008807 Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876 272560008808 metal binding site [ion binding]; metal-binding site 272560008809 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 272560008810 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 272560008811 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560008812 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 272560008813 Pfam match to entry PF01740 STAS, STAS domain , score 33.3, E-value 3.6e-07 272560008814 Pfam match to entry PF00916 Sulfate_transp, Sulfate transporter family , score 152.2, E-value 5.9e-43 272560008815 9 probable transmembrane helices predicted for BPSL1878 by TMHMM2.0 at aa 37-59, 64-86, 107-129, 184-206, 213-230, 265-287, 299-321, 336-353 and 392-414 272560008816 PS00131 Serine carboxypeptidases, serine active site. 272560008817 Putative ParB-like nuclease; Region: ParBc_2; pfam08857 272560008818 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560008819 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 272560008820 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 44.2, E-value 1.9e-10 272560008821 putative sialic acid transporter; Region: 2A0112; TIGR00891 272560008822 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560008823 putative substrate translocation pore; other site 272560008824 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 85.0, E-value 9.8e-23 272560008825 8 probable transmembrane helices predicted for BPSL1881 by TMHMM2.0 at aa 12-31, 46-68, 81-103, 159-181, 210-227, 247-269, 278-300 and 365-387 272560008826 PS00217 Sugar transport proteins signature 2. 272560008827 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560008828 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560008829 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 73.6, E-value 2.8e-19 272560008830 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974 272560008831 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 272560008832 acyl-activating enzyme (AAE) consensus motif; other site 272560008833 putative AMP binding site [chemical binding]; other site 272560008834 putative active site [active] 272560008835 putative CoA binding site [chemical binding]; other site 272560008836 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 453.8, E-value 9.6e-134 272560008837 PS00455 AMP-binding domain signature. 272560008838 Signal peptide predicted for BPSL1884 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.973 between residues 40 and 41; signal peptide 272560008839 Protein of unknown function (DUF1571); Region: DUF1571; pfam07608 272560008840 Signal peptide predicted for BPSL1885 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.862 between residues 26 and 27; signal peptide 272560008841 PXPV repeat (3 copies); Region: PXPV; pfam12778 272560008842 bacterial Hfq-like; Region: Hfq; cd01716 272560008843 hexamer interface [polypeptide binding]; other site 272560008844 Sm1 motif; other site 272560008845 RNA binding site [nucleotide binding]; other site 272560008846 Sm2 motif; other site 272560008847 Signal peptide predicted for BPSL1886 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.497 between residues 27 and 28; signal peptide 272560008848 Protein of unknown function (DUF2968); Region: DUF2968; pfam11180 272560008849 Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113 272560008850 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221 272560008851 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560008852 Walker A motif; other site 272560008853 ATP binding site [chemical binding]; other site 272560008854 Walker B motif; other site 272560008855 arginine finger; other site 272560008856 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560008857 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 53.1, E-value 4e-13 272560008858 Predicted helix-turn-helix motif with score 1200.000, SD 3.27 at aa 427-448, sequence WRRQDTAQHLGISRKVLWEKMR 272560008859 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560008860 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 302.0, E-value 4.7e-88 272560008861 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560008862 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560008863 Predicted membrane protein [Function unknown]; Region: COG4655 272560008864 Putative Tad-like Flp pilus-assembly; Region: Tad_C; pfam09977 272560008865 1 probable transmembrane helix predicted for BPSL1888 by TMHMM2.0 at aa 25-47 272560008866 Signal peptide predicted for BPSL1889 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.894 between residues 38 and 39; signal peptide 272560008867 Protein of unknown function (DUF3613); Region: DUF3613; pfam12266 272560008868 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008869 Signal peptide predicted for BPSL1890 by SignalP 2.0 HMM (Signal peptide probabilty 0.988) with cleavage site probability 0.604 between residues 38 and 39; signal peptide 272560008870 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560008871 TPR repeat; Region: TPR_11; pfam13414 272560008872 binding surface 272560008873 TPR motif; other site 272560008874 Pfam match to entry PF00515 TPR, TPR Domain , score 8.9, E-value 0.33 272560008875 Pfam match to entry PF00515 TPR, TPR Domain , score 17.5, E-value 0.02 272560008876 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008877 Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064 272560008878 4 probable transmembrane helices predicted for BPSL1891 by TMHMM2.0 at aa 10-32, 132-154, 159-178 and 310-332 272560008879 Type II secretion system (T2SS), protein F; Region: T2SF; cl19503 272560008880 5 probable transmembrane helices predicted for BPSL1892 by TMHMM2.0 at aa 4-23, 105-127, 131-153, 277-296 and 311-329 272560008881 sortase-recognition anchor site (LDPTG) 272560008882 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 272560008883 ATP binding site [chemical binding]; other site 272560008884 Walker A motif; other site 272560008885 hexamer interface [polypeptide binding]; other site 272560008886 Walker B motif; other site 272560008887 PS00387 Inorganic pyrophosphatase signature. 272560008888 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score -38.5, E-value 1.1e-07 272560008889 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008890 Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963 272560008891 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078 272560008892 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 272560008893 Signal peptide predicted for BPSL1895 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.988 between residues 22 and 23; signal peptide 272560008894 Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964 272560008895 Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629 272560008896 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560008897 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 203.2, E-value 2.6e-58 272560008898 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 272560008899 1 probable transmembrane helix predicted for BPSL1896 by TMHMM2.0 at aa 5-27 272560008900 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 272560008901 TadE-like protein; Region: TadE; pfam07811 272560008902 1 probable transmembrane helix predicted for BPSL1897 by TMHMM2.0 at aa 20-42 272560008903 Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960 272560008904 3 probable transmembrane helices predicted for BPSL1898 by TMHMM2.0 at aa 4-26, 47-69 and 89-111 272560008905 Pfam match to entry PF01478 Peptidase_C20, Type IV leader peptidase , score 9.2, E-value 0.011 272560008906 Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion]; Region: Flp; COG3847 272560008907 1 probable transmembrane helix predicted for BPSL1899 by TMHMM2.0 at aa 21-43 272560008908 TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920 272560008909 Signal peptide predicted for BPSL1903 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 23 and 24; signal peptide 272560008910 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 272560008911 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 272560008912 Signal peptide predicted for BPSL1904 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.658 between residues 35 and 36; signal peptide 272560008913 Uncharacterized protein conserved in bacteria (DUF2147); Region: DUF2147; pfam09917 272560008914 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008915 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560008916 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560008917 Predicted ATPase [General function prediction only]; Region: COG1485 272560008918 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267 272560008919 Walker B; other site 272560008920 D-loop; other site 272560008921 H-loop/switch region; other site 272560008922 Pfam match to entry PF03969 AFG1_ATPase, AFG1-like ATPase , score 471.8, E-value 3.6e-139 272560008923 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008924 dihydrolipoamide dehydrogenase; Validated; Region: PRK06327 272560008925 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560008926 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560008927 Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852 272560008928 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain , score 199.5, E-value 3.3e-57 272560008929 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 345.4, E-value 4.1e-101 272560008930 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272560008931 dihydrolipoamide succinyltransferase; Validated; Region: PRK05704 272560008932 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 272560008933 E3 interaction surface; other site 272560008934 lipoyl attachment site [posttranslational modification]; other site 272560008935 e3 binding domain; Region: E3_binding; pfam02817 272560008936 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 272560008937 Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain) , score 491.9, E-value 3.3e-145 272560008938 Pfam match to entry PF02817 e3_binding, e3 binding domain , score 48.8, E-value 7.7e-12 272560008939 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 106.8, E-value 2.7e-29 272560008940 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560008941 2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404 272560008942 Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016 272560008943 TPP-binding site [chemical binding]; other site 272560008944 Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779 272560008945 PS00904 Protein prenyltransferases alpha subunit repeat signature. 272560008946 Pfam match to entry PF02779 transket_pyr, Transketolase, pyridine binding domain , score 255.6, E-value 4.5e-74 272560008947 Pfam match to entry PF00676 E1_dehydrog, Dehydrogenase E1 component , score 125.0, E-value 9e-35 272560008948 Transposase domain (DUF772); Region: DUF772; pfam05598 272560008949 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 272560008950 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560008951 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score -2.6, E-value 0.0072 272560008952 Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217 272560008953 Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891 272560008954 G1 box; other site 272560008955 putative GEF interaction site [polypeptide binding]; other site 272560008956 GTP/Mg2+ binding site [chemical binding]; other site 272560008957 Switch I region; other site 272560008958 G2 box; other site 272560008959 G3 box; other site 272560008960 Switch II region; other site 272560008961 G4 box; other site 272560008962 G5 box; other site 272560008963 BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu. BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691 272560008964 Elongation Factor G, domain II; Region: EFG_II; pfam14492 272560008965 BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants. BipA is a highly...; Region: BipA_TypA_C; cd03710 272560008966 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus , score 120.0, E-value 2.9e-33 272560008967 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 47.9, E-value 1.5e-11 272560008968 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 242.9, E-value 3e-70 272560008969 PS00301 GTP-binding elongation factors signature. 272560008970 PS00017 ATP/GTP-binding site motif A (P-loop). 272560008971 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560008972 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 272560008973 putative Zn2+ binding site [ion binding]; other site 272560008974 putative DNA binding site [nucleotide binding]; other site 272560008975 Pfam match to entry PF01047 MarR, MarR family , score 97.9, E-value 1.3e-26 272560008976 Predicted helix-turn-helix motif with score 1289.000, SD 3.58 at aa 64-85, sequence STAAELAREYGIDASAITRLLD 272560008977 Signal peptide predicted for BPSL1913 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.310 between residues 23 and 24; signal peptide 272560008978 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560008979 Outer membrane efflux protein; Region: OEP; pfam02321 272560008980 Outer membrane efflux protein; Region: OEP; pfam02321 272560008981 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560008982 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 117.5, E-value 1.6e-32 272560008983 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 143.1, E-value 3.2e-40 272560008984 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 272560008985 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560008986 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560008987 1 probable transmembrane helix predicted for BPSL1914 by TMHMM2.0 at aa 23-45 272560008988 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 262.1, E-value 4.8e-76 272560008989 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560008990 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560008991 putative substrate translocation pore; other site 272560008992 13 probable transmembrane helices predicted for BPSL1915 by TMHMM2.0 at aa 7-29, 54-76, 83-105, 110-132, 144-166, 171-193, 205-222, 232-254, 273-295, 310-332, 339-356, 371-393 and 478-500 272560008993 tRNA pseudouridine synthase B; Provisional; Region: truB; PRK01851 272560008994 Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573 272560008995 RNA binding site [nucleotide binding]; other site 272560008996 active site 272560008997 Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157 272560008998 Pfam match to entry PF01509 TruB_N, TruB family pseudouridylate synthase (N terminal domain) , score 265.5, E-value 4.5e-77 272560008999 ribosome-binding factor A; Validated; Region: rbfA; PRK00521 272560009000 Pfam match to entry PF02033 RBFA, Ribosome-binding factor A , score 85.7, E-value 6.2e-23 272560009001 Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364 272560009002 translation initiation factor IF-2; Region: IF-2; TIGR00487 272560009003 Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760 272560009004 Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887 272560009005 G1 box; other site 272560009006 putative GEF interaction site [polypeptide binding]; other site 272560009007 GTP/Mg2+ binding site [chemical binding]; other site 272560009008 Switch I region; other site 272560009009 G2 box; other site 272560009010 G3 box; other site 272560009011 Switch II region; other site 272560009012 G4 box; other site 272560009013 G5 box; other site 272560009014 This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702 272560009015 Translation-initiation factor 2; Region: IF-2; pfam11987 272560009016 mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692 272560009017 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 47.7, E-value 1.6e-11 272560009018 PS01176 Initiation factor 2 signature. 272560009019 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 57.8, E-value 1.6e-14 272560009020 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 191.5, E-value 8.4e-55 272560009021 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009022 transcription elongation factor NusA; Validated; Region: nusA; PRK09202 272560009023 NusA N-terminal domain; Region: NusA_N; pfam08529 272560009024 S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455 272560009025 RNA binding site [nucleotide binding]; other site 272560009026 homodimer interface [polypeptide binding]; other site 272560009027 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 272560009028 G-X-X-G motif; other site 272560009029 NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134 272560009030 G-X-X-G motif; other site 272560009031 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 272560009032 transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954 272560009033 Pfam match to entry PF00013 KH, KH domain , score 32.3, E-value 7.4e-07 272560009034 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 42.7, E-value 5.3e-10 272560009035 Sm and related proteins; Region: Sm_like; cl00259 272560009036 Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734 272560009037 putative oligomer interface [polypeptide binding]; other site 272560009038 putative RNA binding site [nucleotide binding]; other site 272560009039 Pfam match to entry PF02576 DUF150, Uncharacterized BCR, YhbC family COG0779 , score 107.0, E-value 2.3e-29 272560009040 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 272560009041 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560009042 RNA binding surface [nucleotide binding]; other site 272560009043 Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556 272560009044 probable active site [active] 272560009045 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 32.9, E-value 9.6e-10 272560009046 PS01149 Rsu family of pseudouridine synthase signature. 272560009047 Pfam match to entry PF01479 S4, S4 domain , score 33.8, E-value 2.5e-07 272560009048 Chromosome segregation and condensation protein B [DNA replication, recombination and repair]; Region: scpB; COG1386 272560009049 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560009050 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009051 TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440 272560009052 putative dimerization interface [polypeptide binding]; other site 272560009053 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 189.5, E-value 3.4e-54 272560009054 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 92.3, E-value 6.3e-25 272560009055 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009056 Predicted helix-turn-helix motif with score 1548.000, SD 4.46 at aa 18-39, sequence KSFSRAGDEIGLTQSAVSRSVR 272560009057 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560009058 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560009059 Predicted helix-turn-helix motif with score 979.000, SD 2.52 at aa 76-97, sequence GTLAEVVKRLGTSGRQISLRGR 272560009060 Signal peptide predicted for BPSL1927 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.593 between residues 50 and 51; signal peptide 272560009061 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 272560009062 putative active site [active] 272560009063 Pfam match to entry PF02698 DUF218, Uncharacterized ACR, COG1434 , score -12.4, E-value 2.7e-06 272560009064 outer membrane protein A; Reviewed; Region: PRK10808 272560009065 Antibiotic biosynthesis monooxygenase; Region: ABM; cl10022 272560009066 Pfam match to entry PF02619 DUF176, Uncharacterized ACR, YneC family COG1359 , score 71.6, E-value 1.1e-18 272560009067 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560009068 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560009069 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560009070 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560009071 Pfam match to entry PF01610 Transposase_12, Transposase , score 371.8, E-value 4.5e-109 272560009072 Signal peptide predicted for BPSL1933 by SignalP 2.0 HMM (Signal peptide probabilty 0.892) with cleavage site probability 0.388 between residues 36 and 37; signal peptide 272560009073 NlpB/DapX lipoprotein; Region: Lipoprotein_18; cl19507 272560009074 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009075 Signal peptide predicted for BPSL1934 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.920 between residues 31 and 32; signal peptide 272560009076 Protein of unknown function (DUF2844); Region: DUF2844; pfam11005 272560009077 Protein of unknown function (DUF3443); Region: DUF3443; pfam11925 272560009078 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560009079 10 probable transmembrane helices predicted for BPSL1936 by TMHMM2.0 at aa 21-40, 50-72, 103-122, 142-164, 176-198, 203-225, 238-260, 265-287, 300-319 and 334-356 272560009080 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 36.6, E-value 3.7e-08 272560009081 Signal peptide predicted for BPSL1937 by SignalP 2.0 HMM (Signal peptide probabilty 0.979) with cleavage site probability 0.373 between residues 21 and 22; signal peptide 272560009082 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009083 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560009084 Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg2; cd04765 272560009085 DNA binding residues [nucleotide binding] 272560009086 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 25.6, E-value 7.7e-05 272560009087 Predicted helix-turn-helix motif with score 1686.000, SD 4.93 at aa 19-40, sequence FTIGEVSELCGVKPHVLRYWEQ 272560009088 Alpha subunit of integration host factor (IHFA); Region: IHF_A; cd13835 272560009089 DNA binding site [nucleotide binding] 272560009090 dimer interface [polypeptide binding]; other site 272560009091 Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein , score 166.7, E-value 2.5e-47 272560009092 PS00045 Bacterial histone-like DNA-binding proteins signature. 272560009093 phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629 272560009094 tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain. PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796 272560009095 putative tRNA-binding site [nucleotide binding]; other site 272560009096 B3/4 domain; Region: B3_4; pfam03483 272560009097 tRNA synthetase B5 domain; Region: B5; smart00874 272560009098 Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an...; Region: PheRS_beta_core; cd00769 272560009099 dimer interface [polypeptide binding]; other site 272560009100 motif 1; other site 272560009101 motif 3; other site 272560009102 motif 2; other site 272560009103 Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896 272560009104 Pfam match to entry PF03147 FDX-ACB, Ferredoxin-fold anticodon binding domain , score 82.6, E-value 5.2e-22 272560009105 Pfam match to entry PF03484 B5, tRNA synthetase B5 domain , score 115.5, E-value 6.4e-32 272560009106 Pfam match to entry PF03483 B3_4, B3/4 domain , score 219.3, E-value 3.8e-63 272560009107 Pfam match to entry PF01588 tRNA_bind, tRNA binding domain , score 130.6, E-value 1.8e-36 272560009108 phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488 272560009109 Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912 272560009110 Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496 272560009111 dimer interface [polypeptide binding]; other site 272560009112 motif 1; other site 272560009113 active site 272560009114 motif 2; other site 272560009115 motif 3; other site 272560009116 Pfam match to entry PF01409 tRNA-synt_2d, tRNA synthetases class II core domain (F) , score 405.9, E-value 2.5e-119 272560009117 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560009118 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560009119 Pfam match to entry PF02912 Phe_tRNA-synt_N, Aminoacyl tRNA synthetase class II, N-terminal domain , score 83.3, E-value 3.2e-22 272560009120 Ribosomal protein L20; Region: Ribosomal_L20; cd07026 272560009121 23S rRNA binding site [nucleotide binding]; other site 272560009122 L21 binding site [polypeptide binding]; other site 272560009123 L13 binding site [polypeptide binding]; other site 272560009124 Pfam match to entry PF00453 Ribosomal_L20, Ribosomal protein L20 , score 202.8, E-value 3.5e-58 272560009125 PS00937 Ribosomal protein L20 signature. 272560009126 50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172 272560009127 Pfam match to entry PF01632 Ribosomal_L35p, Ribosomal protein L35 , score 95.5, E-value 6.9e-26 272560009128 translation initiation factor IF-3; Reviewed; Region: infC; PRK00028 272560009129 Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198 272560009130 Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707 272560009131 Pfam match to entry PF00707 IF3, Translation initiation factor IF-3 , score 289.8, E-value 2.3e-84 272560009132 PS00938 Initiation factor 3 signature. 272560009133 threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413 272560009134 TGS _ThrRS_N: ThrRS (threonyl-tRNA Synthetase) is a class II tRNA synthetase that couples threonine to its cognate tRNA. In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667 272560009135 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 272560009136 Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771 272560009137 active site 272560009138 dimer interface [polypeptide binding]; other site 272560009139 motif 1; other site 272560009140 motif 2; other site 272560009141 motif 3; other site 272560009142 ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860 272560009143 anticodon binding site; other site 272560009144 Pfam match to entry PF03129 HGTP_anticodon, Anticodon binding domain , score 102.4, E-value 5.9e-28 272560009145 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560009146 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T) , score 213.0, E-value 3e-61 272560009147 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560009148 Pfam match to entry PF02824 TGS, TGS domain , score 31.1, E-value 1.7e-06 272560009149 HD domain; Region: HD_4; pfam13328 272560009150 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 272560009151 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 272560009152 synthetase active site [active] 272560009153 NTP binding site [chemical binding]; other site 272560009154 metal binding site [ion binding]; metal-binding site 272560009155 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 272560009156 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 272560009157 Pfam match to entry PF01842 ACT, ACT domain , score 33.3, E-value 3.7e-07 272560009158 Pfam match to entry PF02824 TGS, TGS domain , score 96.9, E-value 2.6e-26 272560009159 This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150 272560009160 homotrimer interaction site [polypeptide binding]; other site 272560009161 putative active site [active] 272560009162 Pfam match to entry PF01042 UPF0076, YjgF family , score 98.8, E-value 6.9e-27 272560009163 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560009164 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560009165 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 45.6, E-value 7.3e-11 272560009166 Partial CDS. Similar to the N-terminal region of Pseudomonas aeruginosa hypothetical protein pa2566 SWALL:Q9I0R9 (EMBL:AE004684) (395 aa) fasta scores: E(): 2.4e-60, 59.09% id in 264 aa, and of Pyrobaculum aerophilum flavoprotein reductase, conjectural pae2618 SWALL:Q8ZUT5 (EMBL:AE009886) (380 aa) fasta scores: E(): 6.5e-19, 30.11% id in 259 aa. Note: CDS lacks a stop codon;conserved hypothetical protein (fragment) 272560009167 LysR family transcriptional regulator; Provisional; Region: PRK14997 272560009168 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009169 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560009170 putative effector binding pocket; other site 272560009171 dimerization interface [polypeptide binding]; other site 272560009172 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 172.0, E-value 6.4e-49 272560009173 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 63.1, E-value 4e-16 272560009174 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009175 Predicted helix-turn-helix motif with score 1423.000, SD 4.03 at aa 19-40, sequence GSLSAAARELDLSLSVVSKRLA 272560009176 Signal peptide predicted for BPSL1951 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 30 and 31; signal peptide 272560009177 SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366 272560009178 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 272560009179 putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212 272560009180 1 probable transmembrane helix predicted for BPSL1952 by TMHMM2.0 at aa 23-45 272560009181 Pfam match to entry PF01522 Polysacc_deacet, Polysaccharide deacetylase , score 71.8, E-value 9.6e-19 272560009182 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560009183 short chain dehydrogenase; Provisional; Region: PRK07041 272560009184 NAD(P) binding site [chemical binding]; other site 272560009185 active site 272560009186 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 102.7, E-value 4.6e-28 272560009187 3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428 272560009188 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase , score 233.8, E-value 1.6e-67 272560009189 PS01274 CoA transferases signature 2. 272560009190 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788 272560009191 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase , score 418.1, E-value 5.2e-123 272560009192 PS01273 CoA transferases signature 1. 272560009193 PAS domain; Region: PAS_9; pfam13426 272560009194 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560009195 putative active site [active] 272560009196 heme pocket [chemical binding]; other site 272560009197 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560009198 DNA binding residues [nucleotide binding] 272560009199 dimerization interface [polypeptide binding]; other site 272560009200 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 53.6, E-value 2.7e-13 272560009201 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009202 PS00622 Bacterial regulatory proteins, luxR family signature. 272560009203 Signal peptide predicted for BPSL1957 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 25 and 26; signal peptide 272560009204 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009205 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 272560009206 active site 272560009207 Pfam match to entry PF03061 4HBT, 4-hydroxybenzoyl-CoA thioesterase , score 50.6, E-value 2.3e-12 272560009208 short chain dehydrogenase; Provisional; Region: PRK06949 272560009209 classical (c) SDRs; Region: SDR_c; cd05233 272560009210 NAD(P) binding site [chemical binding]; other site 272560009211 active site 272560009212 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 274.4, E-value 9.9e-80 272560009213 PS00061 Short-chain dehydrogenases/reductases family signature. 272560009214 Dehydrogenases (flavoproteins) [Energy production and conversion]; Region: FixC; COG0644 272560009215 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560009216 Electron transfer flavoprotein-ubiquinone oxidoreductase; Region: ETF_QO; pfam05187 272560009217 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560009218 Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304 272560009219 Tetramer interface [polypeptide binding]; other site 272560009220 active site 272560009221 FMN-binding site [chemical binding]; other site 272560009222 Pfam match to entry PF01264 Chorismate_synt, Chorismate synthase , score 663.4, E-value 7.6e-197 272560009223 PS00789 Chorismate synthase signature 3. 272560009224 PS00787 Chorismate synthase signature 1. 272560009225 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009226 putative substrate translocation pore; other site 272560009227 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 272560009228 putative acyl-acceptor binding pocket; other site 272560009229 Pfam match to entry PF01553 Acyltransferase, Acyltransferase , score 95.3, E-value 8e-26 272560009230 9 probable transmembrane helices predicted for BPSL1963 by TMHMM2.0 at aa 71-93, 114-136, 165-187, 245-267, 282-301, 308-330, 355-377, 390-412 and 417-439 272560009231 FOG: CBS domain [General function prediction only]; Region: COG0517 272560009232 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 272560009233 Pfam match to entry PF00571 CBS, CBS domain , score 39.9, E-value 3.8e-09 272560009234 Pfam match to entry PF00571 CBS, CBS domain , score 47.5, E-value 2e-11 272560009235 Protein of unknown function (DUF962); Region: DUF962; cl01879 272560009236 2 probable transmembrane helices predicted for BPSL1965 by TMHMM2.0 at aa 31-48 and 52-74 272560009237 Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918 272560009238 Pfam match to entry PF03631 Ribonuclease_BN, Ribonuclease BN-like family , score 206.3, E-value 3e-59 272560009239 5 probable transmembrane helices predicted for BPSL1966 by TMHMM2.0 at aa 27-49, 99-121, 134-156, 176-198 and 238-260 272560009240 NADPH-dependent FMN reductase; Region: FMN_red; cl00438 272560009241 Pfam match to entry PF00258 flavodoxin, Flavodoxin , score 16.3, E-value 0.0001 272560009242 PS00201 Flavodoxin signature. 272560009243 Predicted membrane protein (DUF2069); Region: DUF2069; pfam09842 272560009244 3 probable transmembrane helices predicted for BPSL1968 by TMHMM2.0 at aa 10-32, 39-58 and 93-115 272560009245 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560009246 FAD binding domain; Region: FAD_binding_4; pfam01565 272560009247 FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913 272560009248 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 204.0, E-value 1.5e-58 272560009249 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 232.2, E-value 4.7e-67 272560009250 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560009251 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 272560009252 active site 272560009253 metal binding site [ion binding]; metal-binding site 272560009254 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 60.5, E-value 2.3e-15 272560009255 transcriptional regulator; Provisional; Region: PRK10632 272560009256 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009257 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560009258 putative effector binding pocket; other site 272560009259 dimerization interface [polypeptide binding]; other site 272560009260 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 167.5, E-value 1.5e-47 272560009261 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 65.9, E-value 5.6e-17 272560009262 Predicted helix-turn-helix motif with score 1142.000, SD 3.08 at aa 17-38, sequence GSFTAAAQQLNSTTAYASRAVS 272560009263 Signal peptide predicted for BPSL1972 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.554 between residues 28 and 29; signal peptide 272560009264 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560009265 Outer membrane efflux protein; Region: OEP; pfam02321 272560009266 Outer membrane efflux protein; Region: OEP; pfam02321 272560009267 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009268 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 146.9, E-value 2.4e-41 272560009269 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 130.7, E-value 1.8e-36 272560009270 PS00216 Sugar transport proteins signature 1. 272560009271 Pfam match to entry PF01391 Collagen, Collagen triple helix repeat (20 copies) , score 41.7, E-value 1.1e-09 272560009272 Fusaric acid resistance protein family; Region: FUSC; pfam04632 272560009273 Fusaric acid resistance protein-like; Region: FUSC_2; cl19401 272560009274 11 probable transmembrane helices predicted for BPSL1973 by TMHMM2.0 at aa 32-54, 81-103, 107-125, 132-149, 164-186, 395-417, 421-438, 445-467, 472-489, 496-513 and 528-550 272560009275 Protein of unknown function (DUF1656); Region: DUF1656; pfam07869 272560009276 2 probable transmembrane helices predicted for BPSL1974 by TMHMM2.0 at aa 7-29 and 44-66 272560009277 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 272560009278 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560009279 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560009280 1 probable transmembrane helix predicted for BPSL1975 by TMHMM2.0 at aa 10-32 272560009281 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 86.4, E-value 3.8e-23 272560009282 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560009283 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560009284 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560009285 dimer interface [polypeptide binding]; other site 272560009286 putative CheW interface [polypeptide binding]; other site 272560009287 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 331.7, E-value 5.6e-97 272560009288 2 probable transmembrane helices predicted for BPSL1976 by TMHMM2.0 at aa 40-62 and 225-247 272560009289 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009290 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560009291 putative substrate translocation pore; other site 272560009292 9 probable transmembrane helices predicted for BPSL1977 by TMHMM2.0 at aa 112-134, 155-177, 183-205, 231-253, 268-290, 297-316, 320-342, 351-373 and 383-405 272560009293 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584 272560009294 Pfam match to entry PF01048 PNP_UDP_1, Phosphorylase , score 142.4, E-value 5.4e-40 272560009295 DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773 272560009296 Part of AAA domain; Region: AAA_19; pfam13245 272560009297 UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538 272560009298 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase , score 655.6, E-value 1.7e-194 272560009299 PS00579 Ribosomal protein L29 signature. 272560009300 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009301 valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729 272560009302 catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817 272560009303 active site 272560009304 HIGH motif; other site 272560009305 Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603 272560009306 KMSKS motif; other site 272560009307 Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962 272560009308 tRNA binding surface [nucleotide binding]; other site 272560009309 anticodon binding site; other site 272560009310 Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458 272560009311 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score 920.1, E-value 4.1e-274 272560009312 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560009313 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009314 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 272560009315 dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209 272560009316 active site 272560009317 tetramer interface; other site 272560009318 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 68.0, E-value 1.3e-17 272560009319 Signal peptide predicted for BPSL1982 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.741 between residues 29 and 30; signal peptide 272560009320 Domain of unknown function (DUF4136); Region: DUF4136; pfam13590 272560009321 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009322 CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria; Region: CHASE2; smart01080 272560009323 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 272560009324 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560009325 dimer interface [polypeptide binding]; other site 272560009326 phosphorylation site [posttranslational modification] 272560009327 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560009328 ATP binding site [chemical binding]; other site 272560009329 Mg2+ binding site [ion binding]; other site 272560009330 G-X-G motif; other site 272560009331 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 115.8, E-value 5.2e-32 272560009332 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 20.9, E-value 0.00024 272560009333 4 probable transmembrane helices predicted for BPSL1983 by TMHMM2.0 at aa 15-37, 305-327, 331-353 and 358-377 272560009334 Signal peptide predicted for BPSL1984 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.920 between residues 23 and 24; signal peptide 272560009335 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4254 272560009336 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560009337 FecR protein; Region: FecR; pfam04773 272560009338 Pfam match to entry PF01476 LysM, LysM domain , score 28.7, E-value 8.9e-06 272560009339 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560009340 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009341 active site 272560009342 phosphorylation site [posttranslational modification] 272560009343 intermolecular recognition site; other site 272560009344 dimerization interface [polypeptide binding]; other site 272560009345 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560009346 DNA binding site [nucleotide binding] 272560009347 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 54.0, E-value 2.2e-13 272560009348 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 90.9, E-value 1.7e-24 272560009349 SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291 272560009350 CPxP motif; other site 272560009351 Pfam match to entry PF01206 UPF0033, Uncharacterized protein family UPF0033 , score 75.7, E-value 6.2e-20 272560009352 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 272560009353 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 272560009354 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 272560009355 Pfam match to entry PF02894 GFO_IDH_MocA_C, Oxidoreductase, C-terminal alpha/beta domain , score 26.2, E-value 5.1e-05 272560009356 Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase, NAD-binding Rossmann fold , score 110.7, E-value 1.9e-30 272560009357 Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673 272560009358 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 272560009359 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 272560009360 Pfam match to entry PF02894 GFO_IDH_MocA_C, Oxidoreductase, C-terminal alpha/beta domain , score 31.9, E-value 9.6e-07 272560009361 Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase, NAD-binding Rossmann fold , score 77.1, E-value 2.3e-20 272560009362 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560009363 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560009364 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560009365 putative active site [active] 272560009366 Pfam match to entry PF01380 SIS, SIS domain , score 10.4, E-value 0.00078 272560009367 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 33.6, E-value 7.2e-09 272560009368 Predicted helix-turn-helix motif with score 1157.000, SD 3.13 at aa 47-68, sequence DRTSDIAQRCGVHPSAVVRFAQ 272560009369 Signal peptide predicted for BPSL1991 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.908 between residues 32 and 33; signal peptide 272560009370 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312 272560009371 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560009372 putative ligand binding site [chemical binding]; other site 272560009373 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -53.4, E-value 0.037 272560009374 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560009375 TM-ABC transporter signature motif; other site 272560009376 9 probable transmembrane helices predicted for BPSL1992 by TMHMM2.0 at aa 41-60, 70-92, 97-116, 121-143, 150-172, 223-245, 274-296, 311-342 and 355-374 272560009377 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560009378 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560009379 Walker A/P-loop; other site 272560009380 ATP binding site [chemical binding]; other site 272560009381 Q-loop/lid; other site 272560009382 ABC transporter signature motif; other site 272560009383 Walker B; other site 272560009384 D-loop; other site 272560009385 H-loop/switch region; other site 272560009386 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 160.9, E-value 1.5e-45 272560009387 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009388 PS00211 ABC transporters family signature. 272560009389 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166 272560009390 substrate binding site [chemical binding]; other site 272560009391 ATP binding site [chemical binding]; other site 272560009392 Uncharacterized protein conserved in bacteria (DUF2090); Region: DUF2090; pfam09863 272560009393 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 183.6, E-value 2.1e-52 272560009394 PS00584 pfkB family of carbohydrate kinases signature 2. 272560009395 Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962 272560009396 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560009397 PYR/PP interface [polypeptide binding]; other site 272560009398 dimer interface [polypeptide binding]; other site 272560009399 TPP binding site [chemical binding]; other site 272560009400 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560009401 Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003 272560009402 TPP-binding site; other site 272560009403 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 55.0, E-value 1.1e-13 272560009404 1 probable transmembrane helix predicted for BPSL1995 by TMHMM2.0 at aa 112-134 272560009405 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 88.4, E-value 9.2e-24 272560009406 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009407 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 85.8, E-value 5.6e-23 272560009408 PS00187 Thiamine pyrophosphate enzymes signature. 272560009409 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 272560009410 Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261 272560009411 KduI/IolB family; Region: KduI; cl01508 272560009412 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560009413 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560009414 Walker A/P-loop; other site 272560009415 ATP binding site [chemical binding]; other site 272560009416 Q-loop/lid; other site 272560009417 ABC transporter signature motif; other site 272560009418 Walker B; other site 272560009419 D-loop; other site 272560009420 H-loop/switch region; other site 272560009421 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 167.0, E-value 2.1e-47 272560009422 PS00211 ABC transporters family signature. 272560009423 Signal peptide predicted for BPSL1999 by SignalP 2.0 HMM (Signal peptide probabilty 0.844) with cleavage site probability 0.748 between residues 32 and 33; signal peptide 272560009424 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560009425 TM-ABC transporter signature motif; other site 272560009426 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560009427 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560009428 Walker A/P-loop; other site 272560009429 ATP binding site [chemical binding]; other site 272560009430 Q-loop/lid; other site 272560009431 ABC transporter signature motif; other site 272560009432 Walker B; other site 272560009433 D-loop; other site 272560009434 H-loop/switch region; other site 272560009435 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 149.6, E-value 3.4e-42 272560009436 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009437 11 probable transmembrane helices predicted for BPSL1999 by TMHMM2.0 at aa 13-32, 37-59, 64-81, 91-113, 120-139, 167-189, 216-238, 253-285, 292-314, 334-356 and 377-399 272560009438 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -12.4, E-value 4e-06 272560009439 Signal peptide predicted for BPSL2000 by SignalP 2.0 HMM (Signal peptide probabilty 0.929) with cleavage site probability 0.788 between residues 54 and 55; signal peptide 272560009440 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560009441 TM-ABC transporter signature motif; other site 272560009442 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 72.2, E-value 7.2e-19 272560009443 6 probable transmembrane helices predicted for BPSL2000 by TMHMM2.0 at aa 12-34, 54-76, 137-159, 191-213, 225-247 and 276-298 272560009444 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 272560009445 active site 272560009446 Pfam match to entry PF03061 4HBT, 4-hydroxybenzoyl-CoA thioesterase , score 100.1, E-value 2.8e-27 272560009447 Iron-containing alcohol dehydrogenases-like, involved in the linear alkylbenzenesulfonate (LAS) degradation pathway; Region: Fe-ADH7; cd08192 272560009448 putative active site [active] 272560009449 metal binding site [ion binding]; metal-binding site 272560009450 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase , score 215.1, E-value 7e-62 272560009451 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009452 PS00913 Iron-containing alcohol dehydrogenases signature 1. 272560009453 Putative heavy-metal-binding; Region: YbjQ_1; pfam01906 272560009454 Pfam match to entry PF01906 DUF74, Domain of unknown function DUF74 , score 85.2, E-value 8.9e-23 272560009455 Nudix N-terminal; Region: Nudix_N_2; pfam14803 272560009456 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447 272560009457 nudix motif; other site 272560009458 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 62.8, E-value 4.9e-16 272560009459 PS00893 mutT domain signature. 272560009460 Signal peptide predicted for BPSL2006 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.881 between residues 33 and 34; signal peptide 272560009461 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 272560009462 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 272560009463 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560009464 protein binding site [polypeptide binding]; other site 272560009465 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560009466 protein binding site [polypeptide binding]; other site 272560009467 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 24.9, E-value 0.00013 272560009468 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 25.1, E-value 0.00011 272560009469 Pfam match to entry PF00089 trypsin, Trypsin , score 22.9, E-value 6.3e-08 272560009470 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009471 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009472 putative substrate translocation pore; other site 272560009473 12 probable transmembrane helices predicted for BPSL2007 by TMHMM2.0 at aa 28-50, 65-87, 94-116, 121-143, 150-172, 177-199, 377-399, 414-436, 441-460, 465-484, 497-519 and 529-551 272560009474 high content in Ala, Asp and Thr amino acid residues 272560009475 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560009476 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009477 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560009478 dimerization interface [polypeptide binding]; other site 272560009479 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 95.1, E-value 9.2e-26 272560009480 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009481 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 159.3, E-value 4.2e-45 272560009482 alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252 272560009483 Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673 272560009484 motif 1; other site 272560009485 active site 272560009486 motif 2; other site 272560009487 motif 3; other site 272560009488 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863 272560009489 DHHA1 domain; Region: DHHA1; pfam02272 272560009490 Pfam match to entry PF02272 DHHA1, DHHA1 domain , score 76.2, E-value 4.4e-20 272560009491 Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A) , score 1431.1, E-value 0 272560009492 PS00087 Copper/Zinc superoxide dismutase signature 1. 272560009493 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560009494 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560009495 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 285.9, E-value 3.3e-83 272560009496 Signal peptide predicted for BPSL2011 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.718 between residues 24 and 25; signal peptide 272560009497 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009498 glutaminyl-tRNA synthetase; Provisional; Region: PRK05347 272560009499 catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807 272560009500 active site 272560009501 HIGH motif; other site 272560009502 KMSKS motif; other site 272560009503 tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950 272560009504 Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q), catalytic domain , score 459.5, E-value 1.8e-135 272560009505 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560009506 Pfam match to entry PF03950 tRNA-synt_1c_C, tRNA synthetases class I (E and Q), anti-codon binding domain , score 259.4, E-value 3.1e-75 272560009507 Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883 272560009508 nudix motif; other site 272560009509 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 76.1, E-value 4.7e-20 272560009510 PS00893 mutT domain signature. 272560009511 Signal peptide predicted for BPSL2014 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 28 and 29; signal peptide 272560009512 Signal peptide predicted for BPSL2015 by SignalP 2.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.432 between residues 40 and 41; signal peptide 272560009513 Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472 272560009514 Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; cl08459 272560009515 Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase 3 N terminal domain , score 227.0, E-value 1.7e-65 272560009516 PS00775 Glycosyl hydrolases family 3 active site. 272560009517 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009518 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539 272560009519 Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150 272560009520 di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039 272560009521 PS00190 Cytochrome c family heme-binding site signature. 272560009522 Pfam match to entry PF03150 CCP_MauG, Di-haem cytochrome c peroxidase , score 99.2, E-value 5.1e-27 272560009523 PS00190 Cytochrome c family heme-binding site signature. 272560009524 Phospholipase C [Cell envelope biogenesis, outer membrane]; Region: PlcC; COG3511 272560009525 acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397 272560009526 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560009527 trans-2-enoyl-CoA reductase; Provisional; Region: PRK13656 272560009528 NAD(P)H binding domain of trans-2-enoyl-CoA reductase; Region: Eno-Rase_NADH_b; pfam12242 272560009529 Trans-2-enoyl-CoA reductase catalytic region; Region: Enoyl_reductase; pfam12241 272560009530 Enoyl reductase FAD binding domain; Region: Eno-Rase_FAD_bd; pfam07055 272560009531 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 272560009532 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560009533 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560009534 1 probable transmembrane helix predicted for BPSL2020 by TMHMM2.0 at aa 57-79 272560009535 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 139.3, E-value 4.5e-39 272560009536 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560009537 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009538 putative substrate translocation pore; other site 272560009539 13 probable transmembrane helices predicted for BPSL2021 by TMHMM2.0 at aa 32-54, 69-91, 104-126, 158-180, 187-204, 219-241, 254-276, 291-313, 320-342, 352-371, 392-409, 419-441 and 503-525 272560009540 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -91.6, E-value 0.00013 272560009541 PS00092 N-6 Adenine-specific DNA methylases signature. 272560009542 Signal peptide predicted for BPSL2022 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.793 between residues 22 and 23; signal peptide 272560009543 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560009544 Outer membrane efflux protein; Region: OEP; pfam02321 272560009545 Outer membrane efflux protein; Region: OEP; pfam02321 272560009546 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 75.8, E-value 6e-20 272560009547 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 152.3, E-value 5.3e-43 272560009548 Gene remnant. Similar to the C-terminal region of Escherichia coli trans-aconitate 2-methyltransferase Tam or b1519 SWALL:TAM_ECOLI (SWALL:P76145) (251 aa) fasta scores: E(): 0.014, 31.42% id in 70 aa, and of Pseudomonas aeruginosa trans-aconitate 2-methyltransferase pa2564 SWALL:TAM_PSEAE (SWALL:Q9I0S1) (275 aa) fasta scores: E(): 1.2e-11, 52.85% id in 70 aa. Note: This CDS lack both, start and stop codons; trans-aconitase (fragment) 272560009549 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560009550 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009551 active site 272560009552 phosphorylation site [posttranslational modification] 272560009553 intermolecular recognition site; other site 272560009554 dimerization interface [polypeptide binding]; other site 272560009555 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560009556 DNA binding residues [nucleotide binding] 272560009557 dimerization interface [polypeptide binding]; other site 272560009558 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 75.0, E-value 1e-19 272560009559 Predicted helix-turn-helix motif with score 1332.000, SD 3.72 at aa 161-182, sequence MTMTDIANRYGRSIKTVSTHKH 272560009560 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 78.8, E-value 7.6e-21 272560009561 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560009562 dimer interface [polypeptide binding]; other site 272560009563 phosphorylation site [posttranslational modification] 272560009564 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560009565 ATP binding site [chemical binding]; other site 272560009566 Mg2+ binding site [ion binding]; other site 272560009567 G-X-G motif; other site 272560009568 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009569 active site 272560009570 phosphorylation site [posttranslational modification] 272560009571 intermolecular recognition site; other site 272560009572 dimerization interface [polypeptide binding]; other site 272560009573 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 98.9, E-value 6.4e-27 272560009574 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 125.1, E-value 8.6e-35 272560009575 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 54.2, E-value 1.8e-13 272560009576 1 probable transmembrane helix predicted for BPSL2025 by TMHMM2.0 at aa 13-32 272560009577 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560009578 Signal peptide predicted for BPSL2026 by SignalP 2.0 HMM (Signal peptide probabilty 0.924) with cleavage site probability 0.540 between residues 17 and 18; signal peptide 272560009579 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560009580 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560009581 PapC N-terminal domain; Region: PapC_N; pfam13954 272560009582 Outer membrane usher protein; Region: Usher; pfam00577 272560009583 PapC C-terminal domain; Region: PapC_C; pfam13953 272560009584 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score -235.1, E-value 1e-10 272560009585 Signal peptide predicted for BPSL2028 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 between residues 37 and 38; signal peptide 272560009586 P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121 272560009587 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560009588 Signal peptide predicted for BPSL2029 by SignalP 2.0 HMM (Signal peptide probabilty 0.995) with cleavage site probability 0.688 between residues 22 and 23; signal peptide 272560009589 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560009590 Signal peptide predicted for BPSL2030 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.964 between residues 22 and 23; signal peptide 272560009591 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560009592 Signal peptide predicted for BPSL2031 by SignalP 2.0 HMM (Signal peptide probabilty 0.816) with cleavage site probability 0.752 between residues 41 and 42; signal peptide 272560009593 Spore Coat Protein U domain; Region: SCPU; pfam05229 272560009594 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560009595 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009596 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 272560009597 dimerization interface [polypeptide binding]; other site 272560009598 substrate binding pocket [chemical binding]; other site 272560009599 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 103.2, E-value 3.2e-28 272560009600 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 99.4, E-value 4.7e-27 272560009601 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009602 Predicted helix-turn-helix motif with score 1617.000, SD 4.69 at aa 16-37, sequence GSLTHAAIRLGVAQPALSHALT 272560009603 benzoate transport; Region: 2A0115; TIGR00895 272560009604 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009605 putative substrate translocation pore; other site 272560009606 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 87.1, E-value 2.4e-23 272560009607 9 probable transmembrane helices predicted for BPSL2033 by TMHMM2.0 at aa 50-72, 141-163, 168-187, 226-248, 263-285, 298-317, 322-344, 357-379 and 384-406 272560009608 PS00217 Sugar transport proteins signature 2. 272560009609 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560009610 active site 272560009611 H-NS histone family; Region: Histone_HNS; pfam00816 272560009612 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560009613 Signal peptide predicted for BPSL2036 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.558 between residues 19 and 20; signal peptide 272560009614 3 probable transmembrane helices predicted for BPSL2039 by TMHMM2.0 at aa 820-842, 854-873 and 877-899 272560009615 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 272560009616 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560009617 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560009618 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560009619 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 272560009620 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 272560009621 Signal peptide predicted for BPSL2043 by SignalP 2.0 HMM (Signal peptide probabilty 0.857) with cleavage site probability 0.528 between residues 38 and 39; signal peptide 272560009622 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009623 Signal peptide predicted for BPSL2045 by SignalP 2.0 HMM (Signal peptide probabilty 0.969) with cleavage site probability 0.562 between residues 21 and 22; signal peptide 272560009624 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560009625 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 272560009626 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560009627 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560009628 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 272560009629 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 272560009630 Uncharacterized alpha/beta hydrolase domain (DUF2235); Region: DUF2235; cl01480 272560009631 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 272560009632 Protein of unknown function (DUF3304); Region: DUF3304; pfam11745 272560009633 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 272560009634 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 272560009635 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560009636 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560009637 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 272560009638 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; pfam10106 272560009639 PS00047 Histone H4 signature. 272560009640 PAAR motif; Region: PAAR_motif; pfam05488 272560009641 1 probable transmembrane helix predicted for BPSL2052 by TMHMM2.0 at aa 20-37 272560009642 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 272560009643 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560009644 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560009645 PS00120 Lipases, serine active site. 272560009646 Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652 272560009647 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 272560009648 putative sugar binding sites [chemical binding]; other site 272560009649 Q-X-W motif; other site 272560009650 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 272560009651 putative sugar binding sites [chemical binding]; other site 272560009652 Q-X-W motif; other site 272560009653 Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652 272560009654 Ricin-type beta-trefoil lectin domain-like; Region: RicinB_lectin_2; pfam14200 272560009655 Kelch domain; Region: Kelch; smart00612 272560009656 Kelch motif; Region: Kelch_6; pfam13964 272560009657 C-terminal Early set domain associated with the catalytic domain of galactose oxidase; Region: E_set_GO_C; cd02851 272560009658 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 4.7, E-value 1.2 272560009659 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 40.8, E-value 2e-09 272560009660 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 2.1, E-value 2.8 272560009661 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 26.0, E-value 5.7e-05 272560009662 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 10.5, E-value 0.18 272560009663 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 18.0, E-value 0.015 272560009664 Pfam match to entry PF01344 Kelch, Kelch motif , score 11.5, E-value 0.11 272560009665 Pfam match to entry PF01344 Kelch, Kelch motif , score 15.9, E-value 0.035 272560009666 Signal peptide predicted for BPSL2057 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.957 between residues 35 and 36; signal peptide 272560009667 PS00190 Cytochrome c family heme-binding site signature. 272560009668 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560009669 Cu(I) binding site [ion binding]; other site 272560009670 Signal peptide predicted for BPSL2059 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.552 between residues 18 and 19; signal peptide 272560009671 H-NS histone family; Region: Histone_HNS; pfam00816 272560009672 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560009673 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560009674 TPR repeat; Region: TPR_11; pfam13414 272560009675 binding surface 272560009676 TPR motif; other site 272560009677 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560009678 binding surface 272560009679 TPR motif; other site 272560009680 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009681 Pfam match to entry PF00515 TPR, TPR Domain , score 6.6, E-value 0.57 272560009682 Pfam match to entry PF00515 TPR, TPR Domain , score 20.5, E-value 0.0027 272560009683 Pfam match to entry PF00515 TPR, TPR Domain , score 5.6, E-value 0.73 272560009684 Pfam match to entry PF00515 TPR, TPR Domain , score 9.5, E-value 0.28 272560009685 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560009686 ligand binding site [chemical binding]; other site 272560009687 Pfam match to entry PF00691 OmpA, OmpA family , score 61.2, E-value 1.4e-15 272560009688 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560009689 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560009690 trimer interface [polypeptide binding]; other site 272560009691 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560009692 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560009693 trimer interface [polypeptide binding]; other site 272560009694 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560009695 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 43.0, E-value 4.3e-10 272560009696 1 probable transmembrane helix predicted for BPSL2063 by TMHMM2.0 at aa 36-58 272560009697 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560009698 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009699 active site 272560009700 phosphorylation site [posttranslational modification] 272560009701 intermolecular recognition site; other site 272560009702 dimerization interface [polypeptide binding]; other site 272560009703 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560009704 DNA binding site [nucleotide binding] 272560009705 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 49.6, E-value 4.7e-12 272560009706 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 106.7, E-value 3e-29 272560009707 Signal peptide predicted for BPSL2066 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 between residues 22 and 23; signal peptide 272560009708 Fels-1 Prophage Protein-like; Region: Fels1; pfam05666 272560009709 Fels-1 Prophage Protein-like; Region: Fels1; pfam05666 272560009710 Protein of unknown function (DUF3955); Region: DUF3955; pfam13127 272560009711 2 probable transmembrane helices predicted for BPSL2067 by TMHMM2.0 at aa 5-23 and 38-60 272560009712 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560009713 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009714 active site 272560009715 phosphorylation site [posttranslational modification] 272560009716 intermolecular recognition site; other site 272560009717 dimerization interface [polypeptide binding]; other site 272560009718 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560009719 DNA binding site [nucleotide binding] 272560009720 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 59.6, E-value 4.5e-15 272560009721 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 101.6, E-value 9.7e-28 272560009722 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560009723 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009724 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560009725 dimerization interface [polypeptide binding]; other site 272560009726 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 102.4, E-value 5.7e-28 272560009727 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 96.3, E-value 4e-26 272560009728 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009729 Predicted helix-turn-helix motif with score 1551.000, SD 4.47 at aa 33-54, sequence GSFTAAAGALCLTQSTLTKTIR 272560009730 Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891 272560009731 Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; cl01412 272560009732 1 probable transmembrane helix predicted for BPSL2071 by TMHMM2.0 at aa 4-23 272560009733 Signal peptide predicted for BPSL2073 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.924 between residues 30 and 31; signal peptide 272560009734 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560009735 Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063 272560009736 Interdomain contacts; other site 272560009737 Cytokine receptor motif; other site 272560009738 Pfam match to entry PF00041 fn3, Fibronectin type III domain , score 37.1, E-value 2.6e-08 272560009739 Domain of unknown function (DUF3416); Region: DUF3416; pfam11896 272560009740 Alpha amylase catalytic domain found in GlgE-like proteins; Region: AmyAc_GlgE_like; cd11344 272560009741 Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366 272560009742 active site 272560009743 homodimer interface [polypeptide binding]; other site 272560009744 catalytic site [active] 272560009745 acceptor binding site [chemical binding]; other site 272560009746 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score -72.2, E-value 2.5e-06 272560009747 trehalose synthase; Region: treS_nterm; TIGR02456 272560009748 Alpha amylase catalytic domain found in Trehalose synthetase; Region: AmyAc_TreS; cd11334 272560009749 active site 272560009750 catalytic site [active] 272560009751 trehalose synthase-fused probable maltokinase; Region: TreS_Cterm; TIGR02457 272560009752 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score 226.5, E-value 2.5e-65 272560009753 glycogen branching enzyme; Provisional; Region: PRK05402 272560009754 N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855 272560009755 Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322 272560009756 active site 272560009757 catalytic site [active] 272560009758 Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806 272560009759 Pfam match to entry PF02922 isoamylase_N, Isoamylase N-terminal domain , score 96.9, E-value 2.7e-26 272560009760 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score -75.5, E-value 4.1e-06 272560009761 glycogen debranching enzyme GlgX; Region: glgX_debranch; TIGR02100 272560009762 N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856 272560009763 Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326 272560009764 active site 272560009765 catalytic site [active] 272560009766 Pfam match to entry PF02922 isoamylase_N, Isoamylase N-terminal domain , score 101.4, E-value 1.2e-27 272560009767 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score 13.2, E-value 8e-12 272560009768 N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853 272560009769 malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402 272560009770 Alpha amylase catalytic domain found in Glycosyltrehalose trehalohydrolase (also called Maltooligosyl trehalose Trehalohydrolase); Region: AmyAc_GTHase; cd11325 272560009771 active site 272560009772 catalytic site [active] 272560009773 Domain of unknown function (DUF3459); Region: DUF3459; pfam11941 272560009774 Pfam match to entry PF02922 isoamylase_N, Isoamylase N-terminal domain , score 4.5, E-value 0.0036 272560009775 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score 24.1, E-value 1.6e-12 272560009776 4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052 272560009777 4-alpha-glucanotransferase [Carbohydrate transport and metabolism]; Region: MalQ; COG1640 272560009778 Pfam match to entry PF02446 4A_glucanotrans, 4-alpha-glucanotransferase , score 216.3, E-value 3.1e-62 272560009779 maltooligosyl trehalose synthase; Provisional; Region: PRK14511 272560009780 Alpha amylase catalytic domain found in maltooligosyl trehalose synthase (MTSase); Region: AmyAc_MTSase; cd11336 272560009781 active site 272560009782 catalytic site [active] 272560009783 Pfam match to entry PF00128 alpha-amylase, Alpha amylase, catalytic domain , score -46.3, E-value 5.4e-08 272560009784 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 272560009785 Putative lumazine-binding; Region: Lumazine_bd_2; pfam12893 272560009786 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560009787 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560009788 DNA-binding site [nucleotide binding]; DNA binding site 272560009789 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560009790 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560009791 homodimer interface [polypeptide binding]; other site 272560009792 catalytic residue [active] 272560009793 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 44.7, E-value 1.3e-10 272560009794 Predicted helix-turn-helix motif with score 974.000, SD 2.50 at aa 45-66, sequence PSSRALALHLRVSRNTVCAAIE 272560009795 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560009796 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 272560009797 DNA binding residues [nucleotide binding] 272560009798 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 272560009799 TipAS antibiotic-recognition domain; Region: TipAS; pfam07739 272560009800 O-Methyltransferase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3315 272560009801 Pfam match to entry PF02409 DUF142, Domain of unknown function DUF142 , score -11.4, E-value 9.2e-07 272560009802 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 62.1, E-value 7.8e-16 272560009803 PS00552 Bacterial regulatory proteins, merR family signature. 272560009804 Predicted helix-turn-helix motif with score 1482.000, SD 4.23 at aa 32-53, sequence LKIGELAKKVGLSVRALHHYDA 272560009805 Probable gene remnant. Similar to the C-terminal region of Ralstonia solanacearum ISRso14-transposase OrfB protein SWALL:Q8XF72 (EMBL:AL646083) (275 aa) fasta scores: E(): 2.3e-11, 43.61% id in 94 aa, and to Oligotropha carboxidovorans transposase B SWALL:Q6LB76 (EMBL:X82447) (241 aa) fasta scores: E(): 1.1e-12, 46.15% id in 104 aa;putaive transposase (fragment) 272560009806 Partial CDS. Similar to the N-terminal region of Bacteriophage phiE125 gp29 29 SWALL:Q8W6S2 (EMBL:AF447491) (186 aa) fasta scores: E(): 3e-12, 50.57% id in 87 aa, and to the full length of Pseudomonas aeruginosa hypothetical protein Pa1508 pa1508 SWALL:Q9I3K4 (EMBL:AE004579) (86 aa) fasta scores: E(): 5.9e-11, 50% id in 88 aa. Note: This CDS lacks a stop codon;conserved hypothetical protein (fragment) 272560009807 Domain of unknown function (DUF4123); Region: DUF4123; pfam13503 272560009808 Possible partial CDS. Similar to the C-terminal region of Pseudomonas aeruginosa hypothetical protein Pa3906 pa3906 SWALL:Q9HXA7 (EMBL:AE004808) (127 aa) fasta scores: E(): 6.2e-05, 35.39% id in 113 aa. Note: This CDS lacks of an appropriate stop codon;conserved hypothetical protein (fragment) 272560009809 Restriction endonuclease fold toxin 5; Region: Tox-REase-5; pfam15648 272560009810 Immunity protein 32; Region: Imm32; pfam15579 272560009811 Partial CDS. Similar to the C-terminal region of bacteriophage phiE125 gp27 SWALL:Q8W6S4 (EMBL:AF447491) (262 aa) fasta scores: E(): 2.5e-41, 82.22% id in 135 aa; phage protein (fragment) 272560009812 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 272560009813 active site lid residues [active] 272560009814 substrate binding pocket [chemical binding]; other site 272560009815 catalytic residues [active] 272560009816 substrate-Mg2+ binding site; other site 272560009817 aspartate-rich region 1; other site 272560009818 aspartate-rich region 2; other site 272560009819 Pfam match to entry PF00494 SQS_PSY, Squalene/phytoene synthase , score -14.6, E-value 2.5e-10 272560009820 Protein of unknown function (DUF1501); Region: DUF1501; cl19855 272560009821 Signal peptide predicted for BPSL2091 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.980 between residues 34 and 35 272560009822 Protein of unknown function (DUF1800); Region: DUF1800; pfam08811 272560009823 Signal peptide predicted for BPSL2093 by SignalP 2.0 HMM (Signal peptide probabilty 0.873) with cleavage site probability 0.718 between residues 39 and 40; signal peptide 272560009824 osmolarity response regulator; Provisional; Region: ompR; PRK09468 272560009825 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560009826 active site 272560009827 phosphorylation site [posttranslational modification] 272560009828 intermolecular recognition site; other site 272560009829 dimerization interface [polypeptide binding]; other site 272560009830 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560009831 DNA binding site [nucleotide binding] 272560009832 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 157.1, E-value 2e-44 272560009833 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 121.2, E-value 1.2e-33 272560009834 Signal peptide predicted for BPSL2095 by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.887 between residues 32 and 33; signal peptide 272560009835 osmolarity sensor protein; Provisional; Region: envZ; PRK09467 272560009836 HAMP domain; Region: HAMP; pfam00672 272560009837 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560009838 dimer interface [polypeptide binding]; other site 272560009839 phosphorylation site [posttranslational modification] 272560009840 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560009841 ATP binding site [chemical binding]; other site 272560009842 Mg2+ binding site [ion binding]; other site 272560009843 G-X-G motif; other site 272560009844 Pfam match to entry PF00672 HAMP, HAMP domain , score 39.1, E-value 6.7e-09 272560009845 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 41.4, E-value 1.4e-09 272560009846 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 112.9, E-value 4e-31 272560009847 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 272560009848 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 272560009849 dimer interface [polypeptide binding]; other site 272560009850 decamer (pentamer of dimers) interface [polypeptide binding]; other site 272560009851 catalytic triad [active] 272560009852 peroxidatic and resolving cysteines [active] 272560009853 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 136.4, E-value 3.4e-38 272560009854 alkylhydroperoxidase, AhpD family; Region: ahpD; TIGR00777 272560009855 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 272560009856 MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554 272560009857 homotrimer interaction site [polypeptide binding]; other site 272560009858 zinc binding site [ion binding]; other site 272560009859 CDP-binding sites; other site 272560009860 Pfam match to entry PF02542 YgbB, YgbB family , score 302.2, E-value 4.2e-88 272560009861 CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516 272560009862 substrate binding site; other site 272560009863 dimer interface; other site 272560009864 Pfam match to entry PF01128 IspD, Uncharacterized protein family UPF0007 , score 180.9, E-value 1.3e-51 272560009865 PS01295 Uncharacterized protein family UPF0007 signature. 272560009866 Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197 272560009867 Bifunctional transglycosylase second domain; Region: UB2H; pfam14814 272560009868 CarD-like/TRCF domain; Region: CarD_TRCF; smart01058 272560009869 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560009870 ATP binding site [chemical binding]; other site 272560009871 putative Mg++ binding site [ion binding]; other site 272560009872 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560009873 nucleotide binding region [chemical binding]; other site 272560009874 ATP-binding site [chemical binding]; other site 272560009875 This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982 272560009876 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 125.2, E-value 7.8e-35 272560009877 PS00017 ATP/GTP-binding site motif A (P-loop). 272560009878 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 72.9, E-value 4.4e-19 272560009879 Pfam match to entry PF03461 TRCF, TRCF domain , score 122.4, E-value 5.3e-34 272560009880 acetylornithine deacetylase; Provisional; Region: PRK07522 272560009881 M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894 272560009882 metal binding site [ion binding]; metal-binding site 272560009883 putative dimer interface [polypeptide binding]; other site 272560009884 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 203.3, E-value 2.5e-58 272560009885 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 272560009886 tetramer interface [polypeptide binding]; other site 272560009887 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560009888 catalytic residue [active] 272560009889 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 191.7, E-value 7.5e-55 272560009890 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 272560009891 Signal peptide predicted for BPSL2103 by SignalP 2.0 HMM (Signal peptide probabilty 0.634) with cleavage site probability 0.541 between residues 19 and 20; signal peptide 272560009892 Protein of unknown function (DUF3574); Region: DUF3574; pfam12098 272560009893 Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009 272560009894 Transglycosylase; Region: Transgly; pfam00912 272560009895 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560009896 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 63.8, E-value 2.5e-16 272560009897 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 353.6, E-value 1.4e-103 272560009898 1 probable transmembrane helix predicted for BPSL2104 by TMHMM2.0 at aa 71-93 272560009899 Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842 272560009900 Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113 272560009901 Pfam match to entry PF04012 PspA_IM30, PspA/IM30 family , score 97.8, E-value 1.4e-26 272560009902 Signal peptide predicted for BPSL2106 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 21 and 22; signal peptide 272560009903 Tetratricopeptide repeat; Region: TPR_16; pfam13432 272560009904 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560009905 TPR motif; other site 272560009906 1 probable transmembrane helix predicted for BPSL2106 by TMHMM2.0 at aa 156-173 272560009907 large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952 272560009908 Pfam match to entry PF01741 MscL, Large-conductance mechanosensitive channel, MscL , score 190.2, E-value 2.2e-54 272560009909 1 probable transmembrane helix predicted for BPSL2107 by TMHMM2.0 at aa 141-163 272560009910 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 272560009911 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560009912 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560009913 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score -72.4, E-value 0.0003 272560009914 Dodecin; Region: Dodecin; pfam07311 272560009915 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560009916 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560009917 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_4; cd08463 272560009918 putative substrate binding pocket [chemical binding]; other site 272560009919 putative dimerization interface [polypeptide binding]; other site 272560009920 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 71.5, E-value 1.2e-18 272560009921 Predicted helix-turn-helix motif with score 1334.000, SD 3.73 at aa 50-71, sequence RSVTRAAVKLNQSQPAISAALR 272560009922 PS00044 Bacterial regulatory proteins, lysR family signature. 272560009923 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 78.2, E-value 1.1e-20 272560009924 hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203 272560009925 TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298 272560009926 active site 272560009927 putative substrate binding pocket [chemical binding]; other site 272560009928 Pfam match to entry PF01685 ATZ_TRZ, Chlorohydrolase , score 317.2, E-value 1.3e-92 272560009929 HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822 272560009930 active site 272560009931 homotetramer interface [polypeptide binding]; other site 272560009932 Predicted membrane protein [Function unknown]; Region: COG3748 272560009933 Protein of unknown function (DUF989); Region: DUF989; pfam06181 272560009934 Cytochrome c; Region: Cytochrom_C; pfam00034 272560009935 8 probable transmembrane helices predicted for BPSL2114 by TMHMM2.0 at aa 15-34, 89-111, 121-138, 151-173, 177-199, 226-248, 253-272 and 279-298 272560009936 PS00190 Cytochrome c family heme-binding site signature. 272560009937 ureidoglycolate hydrolase; Provisional; Region: PRK03606 272560009938 allantoicase; Provisional; Region: PRK13257 272560009939 Allantoicase repeat; Region: Allantoicase; pfam03561 272560009940 Allantoicase repeat; Region: Allantoicase; pfam03561 272560009941 Pfam match to entry PF03561 Allantoicase, Allantoicase repeat , score 259.8, E-value 2.3e-75 272560009942 Pfam match to entry PF03561 Allantoicase, Allantoicase repeat , score 280.1, E-value 1.9e-81 272560009943 OHCU decarboxylase; Region: OHCU_decarbox; cl01251 272560009944 putative urate catabolism protein; Region: uraD_N-term-dom; TIGR03212 272560009945 Catalytic domain of bacterial PuuE allantoinases, Schizosaccharomyces pombe chitin deacetylase 1 (SpCDA1), and similar proteins; Region: CE4_PuuE_SpCDA1; cd10977 272560009946 active site 272560009947 catalytic site [active] 272560009948 tetramer interface [polypeptide binding]; other site 272560009949 Pfam match to entry PF01522 Polysacc_deacet, Polysaccharide deacetylase , score -1.1, E-value 4.4e-05 272560009950 Hydantoin racemase [Amino acid transport and metabolism]; Region: COG4126 272560009951 uncharacterized nucleobase-cation-symport-1 (NCS1) transporter subfamily; solute-binding domain; Region: SLC-NCS1sbd_u1; cd11555 272560009952 Na binding site [ion binding]; other site 272560009953 putative substrate binding site [chemical binding]; other site 272560009954 12 probable transmembrane helices predicted for BPSL2120 by TMHMM2.0 at aa 69-91, 96-118, 150-172, 187-209, 221-243, 263-285, 305-327, 347-369, 382-404, 414-436, 465-487 and 491-508 272560009955 Pfam match to entry PF02133 Transp_cyt_pur, Permease for cytosine/purines, uracil, thiamine, allantoin , score 281.9, E-value 5.2e-82 272560009956 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560009957 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560009958 DNA-binding site [nucleotide binding]; DNA binding site 272560009959 FCD domain; Region: FCD; pfam07729 272560009960 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 50.6, E-value 2.3e-12 272560009961 PS00043 Bacterial regulatory proteins, gntR family signature. 272560009962 Predicted helix-turn-helix motif with score 1347.000, SD 3.77 at aa 38-59, sequence LTEAQLCEVFGVKRGAIRQALA 272560009963 LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025 272560009964 dimer interface [polypeptide binding]; other site 272560009965 catalytic triad [active] 272560009966 Pfam match to entry PF02016 UPF0094, Uncharacterized protein family UPF0094 , score 243.8, E-value 1.5e-70 272560009967 Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285 272560009968 nucleoside/Zn binding site; other site 272560009969 dimer interface [polypeptide binding]; other site 272560009970 catalytic motif [active] 272560009971 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region , score 137.7, E-value 1.4e-38 272560009972 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 272560009973 Domain of unknown function (DUF1992); Region: DUF1992; cl08096 272560009974 Domain of unknown function (DUF1993); Region: DUF1993; pfam09351 272560009975 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560009976 putative substrate translocation pore; other site 272560009977 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560009978 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -117.5, E-value 0.001 272560009979 10 probable transmembrane helices predicted for BPSL2126 by TMHMM2.0 at aa 28-50, 65-87, 100-122, 154-176, 183-200, 233-255, 262-284, 308-330, 356-378 and 383-405 272560009980 GMP synthase; Reviewed; Region: guaA; PRK00074 272560009981 Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742 272560009982 AMP/PPi binding site [chemical binding]; other site 272560009983 candidate oxyanion hole; other site 272560009984 catalytic triad [active] 272560009985 potential glutamine specificity residues [chemical binding]; other site 272560009986 The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997 272560009987 ATP Binding subdomain [chemical binding]; other site 272560009988 Ligand Binding sites [chemical binding]; other site 272560009989 Dimerization subdomain; other site 272560009990 Pfam match to entry PF00958 GMP_synt_C, GMP synthase C terminal domain , score 206.1, E-value 3.5e-59 272560009991 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 134.9, E-value 9.4e-38 272560009992 PS00442 Glutamine amidotransferases class-I active site. 272560009993 4 probable transmembrane helices predicted for BPSL2128 by TMHMM2.0 at aa 7-28, 43-65, 78-95 and 105-127 272560009994 inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567 272560009995 IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381 272560009996 active site 272560009997 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein. IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601 272560009998 Pfam match to entry PF00478 IMPDH, IMP dehydrogenase / GMP reductase , score 736.1, E-value 9.9e-219 272560009999 PS00487 IMP dehydrogenase / GMP reductase signature. 272560010000 Pfam match to entry PF00571 CBS, CBS domain , score 44.6, E-value 1.4e-10 272560010001 Pfam match to entry PF00571 CBS, CBS domain , score 56.0, E-value 5.2e-14 272560010002 Bacterial protein of unknown function (DUF899); Region: DUF899; pfam05988 272560010003 Pseudogene. Similar to Rhizobium loti hypothetical protein mll1909 SWALL:Q98JK0 (EMBL:AP002998) (406 aa) fasta scores: E(): 1.8e-56, 54.7% id in 404 aa, and to Rhizobium meliloti hypothetical protein r00749 or smc00804 SWALL:Q92KM5 (EMBL:AL591784) (407 aa) fasta scores: E(): 3e-55, 52.82% id in 407 aa. CDS contains a frameshift mutation (Amber) after codon 211. In comparison to orthologues the CDS also appears to contain an internal deletion after codon 253;conserved hypothetical protein (pseudogene) 272560010004 Glutamine cyclotransferase; Region: Glu_cyclase_2; cl19848 272560010005 Glutamine cyclotransferase; Region: Glu_cyclase_2; cl19848 272560010006 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560010007 10 probable transmembrane helices predicted for BPSL2134 by TMHMM2.0 at aa 5-24, 39-58, 65-84, 89-111, 123-145, 155-177, 190-212, 227-249, 256-278 and 283-302 272560010008 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 22.0, E-value 0.0009 272560010009 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 16.4, E-value 0.0078 272560010010 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2914 272560010011 Pfam match to entry PF03658 UPF0125, Uncharacterised protein family (UPF0125) , score 138.3, E-value 8.8e-39 272560010012 Pfam match to entry PF02824 TGS, TGS domain , score -0.9, E-value 0.022 272560010013 Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813 272560010014 putative coenzyme Q binding site [chemical binding]; other site 272560010015 Pfam match to entry PF03654 UPF0083, Uncharacterised protein family (UPF0083) , score 176.3, E-value 3.3e-50 272560010016 Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294 272560010017 SmpB-tmRNA interface; other site 272560010018 Pfam match to entry PF01668 SmpB, SmpB protein , score 132.1, E-value 6.5e-37 272560010019 PS01317 Protein smpB signature. 272560010020 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 272560010021 Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_paraslipin; cd08829 272560010022 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family , score 251.8, E-value 6e-73 272560010023 1 probable transmembrane helix predicted for BPSL2138 by TMHMM2.0 at aa 4-26 272560010024 NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686 272560010025 2 probable transmembrane helices predicted for BPSL2139 by TMHMM2.0 at aa 7-29 and 44-66 272560010026 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560010027 phosphoenolpyruvate synthase; Validated; Region: PRK06464 272560010028 Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326 272560010029 PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391 272560010030 PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896 272560010031 Pfam match to entry PF02896 PEP-utilizers_C, PEP-utilizing enzyme, TIM barrel domain , score 381.6, E-value 5.2e-112 272560010032 PS00742 PEP-utilizing enzymes signature 2. 272560010033 Pfam match to entry PF00391 PEP-utilizers, PEP-utilizing enzyme, mobile domain , score 147.9, E-value 1.2e-41 272560010034 PS00370 PEP-utilizing enzymes phosphorylation site signature. 272560010035 Pfam match to entry PF01326 PPDK_N_term, Pyruvate phosphate dikinase, PEP/pyruvate binding domain , score 478.8, E-value 2.9e-141 272560010036 Phytochelatin synthase; Region: Phytochelatin; pfam05023 272560010037 Signal peptide predicted for BPSL2142 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.740 between residues 38 and 39; signal peptide 272560010038 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 272560010039 peptidase domain interface [polypeptide binding]; other site 272560010040 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 272560010041 active site 272560010042 catalytic triad [active] 272560010043 calcium binding site [ion binding]; other site 272560010044 PS00138 Serine proteases, subtilase, serine active site. 272560010045 PEP synthetase regulatory protein; Provisional; Region: PRK05339 272560010046 Pfam match to entry PF03618 DUF299, Domain of unknown function (DUF299) , score 394.5, E-value 6.6e-116 272560010047 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010048 rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566 272560010049 SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588 272560010050 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase , score 92.7, E-value 4.7e-25 272560010051 Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182 272560010052 RNA/DNA hybrid binding site [nucleotide binding]; other site 272560010053 active site 272560010054 Pfam match to entry PF01351 RNase_HII, Ribonuclease HII , score 285.7, E-value 3.8e-83 272560010055 lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025 272560010056 ipid-A-disaccharide synthase; Provisional; Region: PRK14089 272560010057 Pfam match to entry PF02684 LpxB, Lipid-A-disaccharide synthetase , score 372.7, E-value 2.4e-109 272560010058 UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289 272560010059 UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351 272560010060 active site 272560010061 PS00101 Hexapeptide-repeat containing-transferases signature. 272560010062 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 7.7, E-value 4.9 272560010063 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 6.7, E-value 6.6 272560010064 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.5, E-value 1.3 272560010065 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 6.0, E-value 8.2 272560010066 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.4, E-value 0.18 272560010067 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 18.8, E-value 0.0086 272560010068 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 8.3, E-value 4.1 272560010069 FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288 272560010070 Pfam match to entry PF01377 Thioester_dehyd, Thioester dehydrase , score 237.9, E-value 9.2e-69 272560010071 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892 272560010072 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613 272560010073 UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352 272560010074 trimer interface [polypeptide binding]; other site 272560010075 active site 272560010076 UDP-GlcNAc binding site [chemical binding]; other site 272560010077 lipid binding site [chemical binding]; lipid-binding site 272560010078 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 2.8, E-value 21 272560010079 PS00101 Hexapeptide-repeat containing-transferases signature. 272560010080 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.2, E-value 0.21 272560010081 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.4, E-value 1.4 272560010082 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 10.7, E-value 2.1 272560010083 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 17.3, E-value 0.024 272560010084 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 17.0, E-value 0.029 272560010085 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 15.5, E-value 0.082 272560010086 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.0, E-value 0.24 272560010087 PS00101 Hexapeptide-repeat containing-transferases signature. 272560010088 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 8.3, E-value 4.2 272560010089 Signal peptide predicted for BPSL2150 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.974 between residues 27 and 28; signal peptide 272560010090 Outer membrane protein (OmpH-like); Region: OmpH; smart00935 272560010091 Pfam match to entry PF03938 OmpH, Outer membrane protein (OmpH-like) , score 108.8, E-value 6.7e-30 272560010092 Signal peptide predicted for BPSL2151 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.983 between residues 27 and 28; signal peptide 272560010093 outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303 272560010094 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560010095 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560010096 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560010097 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560010098 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560010099 Surface antigen; Region: Bac_surface_Ag; pfam01103 272560010100 Pfam match to entry PF01103 Bac_surface_Ag, Bacterial surface antigen , score 726.2, E-value 9.5e-216 272560010101 zinc metallopeptidase RseP; Provisional; Region: PRK10779 272560010102 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 272560010103 active site 272560010104 PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989 272560010105 protein binding site [polypeptide binding]; other site 272560010106 RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163 272560010107 putative substrate binding region [chemical binding]; other site 272560010108 4 probable transmembrane helices predicted for BPSL2152 by TMHMM2.0 at aa 7-29, 100-122, 389-411 and 435-454 272560010109 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 26.0, E-value 5.7e-05 272560010110 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670 272560010111 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK12464 272560010112 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436 272560010113 DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288 272560010114 Pfam match to entry PF02670 DXP_reductoisom, 1-deoxy-D-xylulose 5-phosphate reductoisomerase , score 661.5, E-value 2.8e-196 272560010115 CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575 272560010116 Signal peptide predicted for BPSL2154 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.562 between residues 29 and 30; signal peptide 272560010117 Pfam match to entry PF01148 CTP_transf_1, Phosphatidate cytidylyltransferase , score 173.9, E-value 1.7e-49 272560010118 PS01315 Phosphatidate cytidylyltransferase signature. 272560010119 7 probable transmembrane helices predicted for BPSL2154 by TMHMM2.0 at aa 5-27, 42-64, 71-88, 98-120, 127-146, 166-188 and 195-217 272560010120 Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475 272560010121 active site 272560010122 dimer interface [polypeptide binding]; other site 272560010123 Pfam match to entry PF01255 UPP_synthetase, undecaprenyl diphosphate synthase , score 382.1, E-value 3.5e-112 272560010124 PS01066 Undecaprenyl pyrophosphate synthetase signature. 272560010125 Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation. Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520 272560010126 hinge region; other site 272560010127 Pfam match to entry PF01765 RRF, Ribosome recycling factor , score 298.9, E-value 4.1e-87 272560010128 UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254 272560010129 putative nucleotide binding site [chemical binding]; other site 272560010130 uridine monophosphate binding site [chemical binding]; other site 272560010131 homohexameric interface [polypeptide binding]; other site 272560010132 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 222.6, E-value 3.8e-64 272560010133 elongation factor Ts; Provisional; Region: tsf; PRK09377 272560010134 UBA/TS-N domain; Region: UBA; pfam00627 272560010135 Pfam match to entry PF00889 EF_TS, Elongation factor TS , score 326.8, E-value 1.6e-95 272560010136 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010137 PS01127 Elongation factor Ts signature 2. 272560010138 Pfam match to entry PF00627 UBA, UBA/TS-N domain , score 38.4, E-value 1.1e-08 272560010139 Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425 272560010140 rRNA interaction site [nucleotide binding]; other site 272560010141 S8 interaction site; other site 272560010142 putative laminin-1 binding site; other site 272560010143 Pfam match to entry PF00318 Ribosomal_S2, Ribosomal protein S2 , score 336.0, E-value 2.7e-98 272560010144 PS00962 Ribosomal protein S2 signature 1. 272560010145 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 272560010146 active site 272560010147 Pfam match to entry PF00557 Peptidase_M24, metallopeptidase M24 , score 285.2, E-value 5.5e-83 272560010148 PS00680 Methionine aminopeptidase subfamily 1 signature. 272560010149 PII uridylyl-transferase; Provisional; Region: PRK03059 272560010150 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 272560010151 metal binding triad; other site 272560010152 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 272560010153 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560010154 Zn2+ binding site [ion binding]; other site 272560010155 Mg2+ binding site [ion binding]; other site 272560010156 ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900 272560010157 C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899 272560010158 Pfam match to entry PF01909 NTP_transf_2, Nucleotidyltransferase domain , score 47.9, E-value 1.4e-11 272560010159 Pfam match to entry PF01966 HD, HD domain , score 48.3, E-value 1.1e-11 272560010160 Pfam match to entry PF01842 ACT, ACT domain , score 17.4, E-value 0.022 272560010161 Pfam match to entry PF01842 ACT, ACT domain , score 24.5, E-value 0.00016 272560010162 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187 272560010163 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560010164 RNA binding surface [nucleotide binding]; other site 272560010165 Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130 272560010166 active site 272560010167 Pfam match to entry PF01479 S4, S4 domain , score 45.3, E-value 8.8e-11 272560010168 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 18.3, E-value 2.5e-08 272560010169 Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487 272560010170 active site 272560010171 catalytic residues [active] 272560010172 metal binding site [ion binding]; metal-binding site 272560010173 Pfam match to entry PF01327 Pep_deformylase, Polypeptide deformylase , score 146.8, E-value 2.5e-41 272560010174 PS00430 TonB-dependent receptor proteins signature 1. 272560010175 NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956 272560010176 NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114 272560010177 nucleotide binding pocket [chemical binding]; other site 272560010178 K-X-D-G motif; other site 272560010179 catalytic site [active] 272560010180 NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120 272560010181 NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119 272560010182 Helix-hairpin-helix domain; Region: HHH_5; pfam14520 272560010183 Helix-hairpin-helix motif; Region: HHH_2; pfam12826 272560010184 Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027 272560010185 Dimer interface [polypeptide binding]; other site 272560010186 Pfam match to entry PF00533 BRCT, BRCA1 C Terminus (BRCT) domain , score 59.7, E-value 4e-15 272560010187 Pfam match to entry PF03119 DNA_ligase_ZBD, NAD-dependent DNA ligase C4 zinc finger domain , score 50.3, E-value 2.8e-12 272560010188 Pfam match to entry PF03120 DNA_ligase_OB, NAD-dependent DNA ligase OB-fold domain , score 180.9, E-value 1.3e-51 272560010189 PS01056 NAD-dependent DNA ligase signature 2. 272560010190 Pfam match to entry PF01653 DNA_ligase_N, NAD-dependent DNA ligase adenylation domain , score 554.8, E-value 3.7e-164 272560010191 ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cl12038 272560010192 1 probable transmembrane helix predicted for BPSL2165 by TMHMM2.0 at aa 9-31 272560010193 chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168 272560010194 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 272560010195 Walker A/P-loop; other site 272560010196 ATP binding site [chemical binding]; other site 272560010197 Q-loop/lid; other site 272560010198 SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968 272560010199 Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits...; Region: Prefoldin; cl09111 272560010200 ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278 272560010201 Q-loop/lid; other site 272560010202 ABC transporter signature motif; other site 272560010203 Walker B; other site 272560010204 D-loop; other site 272560010205 H-loop/switch region; other site 272560010206 Pfam match to entry PF02483 SMC_C, SMC family, C-terminal domain , score 261.7, E-value 6.2e-76 272560010207 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560010208 Pfam match to entry PF02463 SMC_N, RecF/RecN/SMC N terminal domain , score 184.4, E-value 1.2e-52 272560010209 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010210 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560010211 EamA-like transporter family; Region: EamA; pfam00892 272560010212 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 53.5, E-value 3e-13 272560010213 9 probable transmembrane helices predicted for BPSL2167 by TMHMM2.0 at aa 7-29, 34-56, 69-91, 95-117, 124-141, 156-173, 186-205, 220-238 and 250-269 272560010214 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 19.9, E-value 0.0039 272560010215 succinyldiaminopimelate transaminase; Provisional; Region: PRK09147 272560010216 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560010217 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560010218 homodimer interface [polypeptide binding]; other site 272560010219 catalytic residue [active] 272560010220 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 45.2, E-value 9.2e-11 272560010221 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830 272560010222 Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805 272560010223 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350 272560010224 trimer interface [polypeptide binding]; other site 272560010225 active site 272560010226 substrate binding site [chemical binding]; other site 272560010227 CoA binding site [chemical binding]; other site 272560010228 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 5.3, E-value 10 272560010229 PS00101 Hexapeptide-repeat containing-transferases signature. 272560010230 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 13.3, E-value 0.39 272560010231 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.0, E-value 1.9 272560010232 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 13.1, E-value 0.44 272560010233 Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035 272560010234 putative catalytic residues [active] 272560010235 Pfam match to entry PF03960 ArsC, ArsC family , score 94.8, E-value 1.1e-25 272560010236 succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009 272560010237 M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891 272560010238 metal binding site [ion binding]; metal-binding site 272560010239 dimer interface [polypeptide binding]; other site 272560010240 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 285.3, E-value 5.2e-83 272560010241 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 272560010242 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK11805 272560010243 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560010244 S-adenosylmethionine binding site [chemical binding]; other site 272560010245 PS00092 N-6 Adenine-specific DNA methylases signature. 272560010246 cardiolipin synthetase; Reviewed; Region: cls; PRK01642 272560010247 Putative catalytic domain, repeat 1, of Pseudomonas aeruginosa cardiolipin synthase and similar proteins; Region: PLDc_PaCLS_like_1; cd09155 272560010248 putative active site [active] 272560010249 catalytic site [active] 272560010250 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 272560010251 putative active site [active] 272560010252 catalytic site [active] 272560010253 2 probable transmembrane helices predicted for BPSL2174 by TMHMM2.0 at aa 6-28 and 35-57 272560010254 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 38.0, E-value 1.4e-08 272560010255 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 31.2, E-value 1.6e-06 272560010256 Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340 272560010257 catalytic residues [active] 272560010258 dimer interface [polypeptide binding]; other site 272560010259 Pfam match to entry PF00255 GSHPx, Glutathione peroxidase , score 210.5, E-value 1.6e-60 272560010260 PS00763 Glutathione peroxidases signature 2. 272560010261 PS00460 Glutathione peroxidases selenocysteine active site. 272560010262 putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636 272560010263 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560010264 ABC transporter; Region: ABC_tran_2; pfam12848 272560010265 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560010266 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 155.7, E-value 5.2e-44 272560010267 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010268 PS00211 ABC transporters family signature. 272560010269 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 120.3, E-value 2.4e-33 272560010270 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010271 PS00211 ABC transporters family signature. 272560010272 Protein of unknown function (DUF2866); Region: DUF2866; pfam11065 272560010273 DNA repair protein RadA; Provisional; Region: PRK11823 272560010274 Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121 272560010275 Walker A motif/ATP binding site; other site 272560010276 ATP binding site [chemical binding]; other site 272560010277 Walker B motif; other site 272560010278 Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541 272560010279 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010280 alanine racemase; Reviewed; Region: dadX; PRK03646 272560010281 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 272560010282 active site 272560010283 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560010284 substrate binding site [chemical binding]; other site 272560010285 catalytic residues [active] 272560010286 dimer interface [polypeptide binding]; other site 272560010287 Pfam match to entry PF00842 Ala_racemase, Alanine racemase , score 477.9, E-value 5.3e-141 272560010288 lysophospholipid transporter LplT; Provisional; Region: PRK11195 272560010289 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560010290 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560010291 putative substrate translocation pore; other site 272560010292 10 probable transmembrane helices predicted for BPSL2180 by TMHMM2.0 at aa 13-30, 40-62, 83-105, 170-189, 223-245, 260-282, 289-311, 326-348, 369-391 and 395-414 272560010293 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score -78.0, E-value 0.068 272560010294 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 272560010295 dimer interface [polypeptide binding]; other site 272560010296 substrate binding site [chemical binding]; other site 272560010297 ATP binding site [chemical binding]; other site 272560010298 Domain of unknown function (DUF1853); Region: DUF1853; pfam08907 272560010299 Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030 272560010300 Fe-S cluster binding site [ion binding]; other site 272560010301 active site 272560010302 Pfam match to entry PF03167 UDG, Uracil DNA glycosylase superfamily , score 109.1, E-value 5.7e-30 272560010303 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 272560010304 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560010305 Coenzyme A binding pocket [chemical binding]; other site 272560010306 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560010307 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 72.7, E-value 5e-19 272560010308 tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725 272560010309 Glycoprotease family; Region: Peptidase_M22; pfam00814 272560010310 Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; Region: ACBP; cl00221 272560010311 acyl-CoA binding pocket [chemical binding]; other site 272560010312 CoA binding site [chemical binding]; other site 272560010313 Pfam match to entry PF00887 ACBP, Acyl CoA binding protein , score 142.5, E-value 4.9e-40 272560010314 ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590 272560010315 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 272560010316 ATP binding site [chemical binding]; other site 272560010317 Mg++ binding site [ion binding]; other site 272560010318 motif III; other site 272560010319 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560010320 nucleotide binding region [chemical binding]; other site 272560010321 ATP-binding site [chemical binding]; other site 272560010322 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 260.9, E-value 1.1e-75 272560010323 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 272560010324 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 121.8, E-value 8.4e-34 272560010325 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 272560010326 tetramer interface [polypeptide binding]; other site 272560010327 active site 272560010328 Mg2+/Mn2+ binding site [ion binding]; other site 272560010329 Pfam match to entry PF00463 ICL, Isocitrate lyase , score 819.3, E-value 9.2e-244 272560010330 PS00161 Isocitrate lyase signature. 272560010331 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 272560010332 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560010333 Ligand Binding Site [chemical binding]; other site 272560010334 Pfam match to entry PF00582 Usp, Universal stress protein family , score 39.3, E-value 5.6e-09 272560010335 Signal peptide predicted for BPSL2190 by SignalP 2.0 HMM (Signal peptide probabilty 0.993) with cleavage site probability 0.975 between residues 25 and 26; signal peptide 272560010336 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560010337 transcriptional activator TtdR; Provisional; Region: PRK09801 272560010338 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560010339 putative effector binding pocket; other site 272560010340 dimerization interface [polypeptide binding]; other site 272560010341 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 168.1, E-value 9.8e-48 272560010342 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 61.5, E-value 1.2e-15 272560010343 2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428 272560010344 Haloacid dehalogenase superfamily, subfamily IA, variant 2 with 3rd motif like haloacid dehalogenase; Region: HAD-SF-IA-v2; TIGR01493 272560010345 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560010346 motif II; other site 272560010347 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 86.8, E-value 2.8e-23 272560010348 Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727 272560010349 active site 272560010350 Pfam match to entry PF01274 Malate_synthase, Malate synthase , score 1004.9, E-value 1.2e-299 272560010351 PS00510 Malate synthase signature. 272560010352 Predicted helix-turn-helix motif with score 1613.000, SD 4.68 at aa 442-463, sequence HNLMEDAATAEISRSQVWQWIR 272560010353 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 272560010354 putative active site pocket [active] 272560010355 dimerization interface [polypeptide binding]; other site 272560010356 putative catalytic residue [active] 272560010357 ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372 272560010358 Pfam match to entry PF03737 Methyltransf_6, Dimethylmenaquinone methyltransferase , score 203.4, E-value 2.2e-58 272560010359 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560010360 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560010361 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560010362 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560010363 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 21.0, E-value 0.0018 272560010364 Predicted helix-turn-helix motif with score 1241.000, SD 3.41 at aa 183-204, sequence ESLEHWAAGVGASTRTIARLFK 272560010365 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 31.3, E-value 1.5e-06 272560010366 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560010367 Coenzyme A binding pocket [chemical binding]; other site 272560010368 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 45.8, E-value 6.2e-11 272560010369 glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406 272560010370 catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808 272560010371 active site 272560010372 HIGH motif; other site 272560010373 KMSKS motif; other site 272560010374 Pfam match to entry PF00749 tRNA-synt_1c, tRNA synthetases class I (E and Q), catalytic domain , score 459.7, E-value 1.6e-135 272560010375 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560010376 Signal peptide predicted for BPSL2198 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.458 between residues 28 and 29; signal peptide 272560010377 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 272560010378 Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205 272560010379 active site 272560010380 nucleophile elbow; other site 272560010381 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560010382 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 160.7, E-value 1.6e-45 272560010383 Signal peptide predicted for BPSL2199 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 31 and 32; signal peptide 272560010384 Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791 272560010385 NlpC/P60 family; Region: NLPC_P60; pfam00877 272560010386 Pfam match to entry PF00877 NLPC_P60, NLP/P60 family , score 190.9, E-value 1.3e-54 272560010387 ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only]; Region: COG4172 272560010388 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560010389 Walker A/P-loop; other site 272560010390 ATP binding site [chemical binding]; other site 272560010391 Q-loop/lid; other site 272560010392 ABC transporter signature motif; other site 272560010393 Walker B; other site 272560010394 D-loop; other site 272560010395 H-loop/switch region; other site 272560010396 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560010397 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560010398 Walker A/P-loop; other site 272560010399 ATP binding site [chemical binding]; other site 272560010400 Q-loop/lid; other site 272560010401 ABC transporter signature motif; other site 272560010402 Walker B; other site 272560010403 D-loop; other site 272560010404 H-loop/switch region; other site 272560010405 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560010406 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 221.8, E-value 6.4e-64 272560010407 PS00211 ABC transporters family signature. 272560010408 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010409 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 208.0, E-value 9.3e-60 272560010410 PS00211 ABC transporters family signature. 272560010411 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010412 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4239 272560010413 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560010414 dimer interface [polypeptide binding]; other site 272560010415 conserved gate region; other site 272560010416 putative PBP binding loops; other site 272560010417 ABC-ATPase subunit interface; other site 272560010418 4 probable transmembrane helices predicted for BPSL2201 by TMHMM2.0 at aa 34-56, 161-183, 204-226 and 321-343 272560010419 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 77.5, E-value 1.8e-20 272560010420 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560010421 ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174 272560010422 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560010423 dimer interface [polypeptide binding]; other site 272560010424 conserved gate region; other site 272560010425 putative PBP binding loops; other site 272560010426 ABC-ATPase subunit interface; other site 272560010427 6 probable transmembrane helices predicted for BPSL2202 by TMHMM2.0 at aa 54-76, 163-185, 197-219, 249-271, 308-330 and 358-380 272560010428 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 42.7, E-value 5.5e-10 272560010429 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 272560010430 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 272560010431 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497 272560010432 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score -35.7, E-value 6.6e-13 272560010433 PS01310 ATP1G1 / PLM / MAT8 family signature. 272560010434 1 probable transmembrane helix predicted for BPSL2203 by TMHMM2.0 at aa 46-68 272560010435 enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK06997 272560010436 Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372 272560010437 NAD binding site [chemical binding]; other site 272560010438 homotetramer interface [polypeptide binding]; other site 272560010439 homodimer interface [polypeptide binding]; other site 272560010440 substrate binding site [chemical binding]; other site 272560010441 active site 272560010442 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 53.8, E-value 2.5e-13 272560010443 Signal peptide predicted for BPSL2205 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 24 and 25; signal peptide 272560010444 2 probable transmembrane helices predicted for BPSL2205 by TMHMM2.0 at aa 13-35 and 55-77 272560010445 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 272560010446 The MopB_1 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members belong to...; Region: MopB_1; cd02762 272560010447 putative [Fe4-S4] binding site [ion binding]; other site 272560010448 putative molybdopterin cofactor binding site [chemical binding]; other site 272560010449 The MopB_CT_1 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_1; cd02782 272560010450 putative molybdopterin cofactor binding site; other site 272560010451 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 53.5, E-value 3e-13 272560010452 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 173.8, E-value 1.8e-49 272560010453 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 272560010454 Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195 272560010455 FAD binding pocket [chemical binding]; other site 272560010456 FAD binding motif [chemical binding]; other site 272560010457 phosphate binding motif [ion binding]; other site 272560010458 beta-alpha-beta structure motif; other site 272560010459 NAD binding pocket [chemical binding]; other site 272560010460 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 21.1, E-value 8.6e-06 272560010461 molybdenum cofactor biosynthesis protein A; Provisional; Region: PRK13361 272560010462 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560010463 FeS/SAM binding site; other site 272560010464 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 272560010465 Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / nifB / pqqE family , score 190.5, E-value 1.7e-54 272560010466 Ferredoxin [Energy production and conversion]; Region: COG1146 272560010467 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560010468 Domain of unknown function (DUF3470); Region: DUF3470; pfam11953 272560010469 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 32.1, E-value 8.4e-07 272560010470 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560010471 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560010472 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560010473 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 41.5, E-value 1.2e-09 272560010474 Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086 272560010475 active site 272560010476 Pfam match to entry PF00557 Peptidase_M24, metallopeptidase M24 , score 271.4, E-value 7.7e-79 272560010477 PS00680 Methionine aminopeptidase subfamily 1 signature. 272560010478 Protein of unknown function (DUF3423); Region: DUF3423; pfam11903 272560010479 argininosuccinate lyase; Provisional; Region: PRK02186 272560010480 ATP-grasp domain; Region: ATP-grasp_4; pfam13535 272560010481 Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013 272560010482 tetramer interface [polypeptide binding]; other site 272560010483 Pfam match to entry PF00206 lyase_1, Lyase , score 61.9, E-value 8.7e-16 272560010484 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560010485 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 272560010486 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560010487 catalytic residue [active] 272560010488 dimer interface [polypeptide binding]; other site 272560010489 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 49.0, E-value 6.8e-12 272560010490 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170 272560010491 G1 box; other site 272560010492 GTP/Mg2+ binding site [chemical binding]; other site 272560010493 Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542 272560010494 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 272560010495 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein , score -24.7, E-value 0.0011 272560010496 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175 272560010497 This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713 272560010498 Active Sites [active] 272560010499 Pfam match to entry PF01507 PAPS_reduct, Phosphoadenosine phosphosulfate reductase , score 167.4, E-value 1.5e-47 272560010500 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560010501 active site 272560010502 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 19.7, E-value 0.00045 272560010503 phosphoserine aminotransferase; Provisional; Region: PRK12462 272560010504 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560010505 catalytic residue [active] 272560010506 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 117.3, E-value 1.9e-32 272560010507 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560010508 10 probable transmembrane helices predicted for BPSL2220 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 153-175, 180-199, 204-226, 239-256, 260-282, 295-317 and 332-354 272560010509 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 10.4, E-value 1.2e-06 272560010510 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 272560010511 Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958 272560010512 PYR/PP interface [polypeptide binding]; other site 272560010513 dimer interface [polypeptide binding]; other site 272560010514 TPP binding site [chemical binding]; other site 272560010515 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 272560010516 Pfam match to entry PF02780 transketolase_C, Transketolase, C-terminal domain , score -1.2, E-value 0.00083 272560010517 Pfam match to entry PF02779 transket_pyr, Transketolase, pyridine binding domain , score 94.5, E-value 1.4e-25 272560010518 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 272560010519 TPP-binding site [chemical binding]; other site 272560010520 dimer interface [polypeptide binding]; other site 272560010521 Pfam match to entry PF00456 transketolase, Transketolase, thiamine diphosphate binding domain , score 40.6, E-value 1.4e-18 272560010522 PS00801 Transketolase signature 1. 272560010523 TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305 272560010524 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560010525 S-adenosylmethionine binding site [chemical binding]; other site 272560010526 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560010527 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 272560010528 active site 272560010529 iron coordination sites [ion binding]; other site 272560010530 substrate binding pocket [chemical binding]; other site 272560010531 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 206.5, E-value 2.7e-59 272560010532 Sulfotransferase family; Region: Sulfotransfer_2; cl19526 272560010533 Condensation domain; Region: Condensation; cl19241 272560010534 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560010535 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560010536 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560010537 acyl-activating enzyme (AAE) consensus motif; other site 272560010538 AMP binding site [chemical binding]; other site 272560010539 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560010540 Condensation domain; Region: Condensation; cl19241 272560010541 non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261 272560010542 Condensation domain; Region: Condensation; cl19241 272560010543 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560010544 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560010545 acyl-activating enzyme (AAE) consensus motif; other site 272560010546 AMP binding site [chemical binding]; other site 272560010547 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560010548 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560010549 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560010550 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 53.9, E-value 2.3e-13 272560010551 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 432.2, E-value 3e-127 272560010552 PS00455 AMP-binding domain signature. 272560010553 Pfam match to entry PF00668 Condensation, Condensation domain , score 190.0, E-value 2.5e-54 272560010554 Pfam match to entry PF00668 Condensation, Condensation domain , score 123.9, E-value 1.9e-34 272560010555 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 71.3, E-value 1.3e-18 272560010556 PS00012 Phosphopantetheine attachment site. 272560010557 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 483.9, E-value 8.3e-143 272560010558 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560010559 PS00455 AMP-binding domain signature. 272560010560 Pfam match to entry PF00668 Condensation, Condensation domain , score 203.8, E-value 1.7e-58 272560010561 Signal peptide predicted for BPSL2230 by SignalP 2.0 HMM (Signal peptide probabilty 0.677) with cleavage site probability 0.556 between residues 19 and 20; signal peptide 272560010562 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529 272560010563 FAD-NAD(P)-binding; Region: NAD_binding_9; pfam13454 272560010564 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560010565 H+ Antiporter protein; Region: 2A0121; TIGR00900 272560010566 putative substrate translocation pore; other site 272560010567 10 probable transmembrane helices predicted for BPSL2231 by TMHMM2.0 at aa 34-56, 66-88, 100-122, 182-204, 244-266, 276-298, 305-327, 331-353, 366-388 and 393-415 272560010568 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560010569 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560010570 acyl-activating enzyme (AAE) consensus motif; other site 272560010571 AMP binding site [chemical binding]; other site 272560010572 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560010573 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 83.9, E-value 2.2e-22 272560010574 PS00012 Phosphopantetheine attachment site. 272560010575 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 333.6, E-value 1.5e-97 272560010576 PS00455 AMP-binding domain signature. 272560010577 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560010578 S-adenosylmethionine binding site [chemical binding]; other site 272560010579 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 272560010580 ligand-binding site [chemical binding]; other site 272560010581 Pfam match to entry PF01583 APS_kinase, Adenylylsulfate kinase , score 266.0, E-value 3.2e-77 272560010582 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010583 Signal peptide predicted for BPSL2234 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.667 between residues 36 and 37; signal peptide 272560010584 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 272560010585 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560010586 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560010587 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 68.5, E-value 9.3e-18 272560010588 multidrug efflux system subunit MdtB; Provisional; Region: PRK10503 272560010589 MMPL family; Region: MMPL; cl14618 272560010590 hypothetical protein; Validated; Region: PRK07668 272560010591 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1080.8, E-value 0 272560010592 10 probable transmembrane helices predicted for BPSL2235 by TMHMM2.0 at aa 7-29, 333-355, 362-384, 437-459, 466-488, 529-551, 863-885, 905-927, 958-980 and 995-1017 272560010593 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560010594 8 probable transmembrane helices predicted for BPSL2236 by TMHMM2.0 at aa 119-141, 189-211, 241-263, 273-295, 306-323, 327-349, 362-384 and 394-416 272560010595 Fatty acyltransferase-like subfamily of the SGNH hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its...; Region: fatty_acyltransferase_like; cd01846 272560010596 active site 272560010597 catalytic triad [active] 272560010598 oxyanion hole [active] 272560010599 Autotransporter beta-domain; Region: Autotransporter; smart00869 272560010600 1 probable transmembrane helix predicted for BPSL2237 by TMHMM2.0 at aa 56-75 272560010601 single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644 272560010602 aspartate kinase; Reviewed; Region: PRK06635 272560010603 AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261 272560010604 putative nucleotide binding site [chemical binding]; other site 272560010605 putative catalytic residues [active] 272560010606 putative Mg ion binding site [ion binding]; other site 272560010607 putative aspartate binding site [chemical binding]; other site 272560010608 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913 272560010609 putative allosteric regulatory site; other site 272560010610 ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923 272560010611 Pfam match to entry PF01842 ACT, ACT domain , score 39.8, E-value 4.2e-09 272560010612 Pfam match to entry PF01842 ACT, ACT domain , score 42.4, E-value 6.8e-10 272560010613 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 224.2, E-value 1.2e-64 272560010614 N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992 272560010615 tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660 272560010616 Ligand Binding Site [chemical binding]; other site 272560010617 TilS substrate binding domain; Region: TilS; pfam09179 272560010618 TilS substrate C-terminal domain; Region: TilS_C; pfam11734 272560010619 acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724 272560010620 Pfam match to entry PF03255 ACCA, Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit , score 305.9, E-value 3.2e-89 272560010621 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122 272560010622 endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056 272560010623 minor groove reading motif; other site 272560010624 helix-hairpin-helix signature motif; other site 272560010625 substrate binding pocket [chemical binding]; other site 272560010626 active site 272560010627 Pfam match to entry PF00730 HhH-GPD, HhH-GPD superfamily base excision DNA repair protein , score -13.9, E-value 5.2e-05 272560010628 cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260 272560010629 catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672 272560010630 active site 272560010631 HIGH motif; other site 272560010632 KMSKS motif; other site 272560010633 Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963 272560010634 tRNA binding surface [nucleotide binding]; other site 272560010635 anticodon binding site; other site 272560010636 Pfam match to entry PF01406 tRNA-synt_1e, tRNA synthetases class I (C) , score 731.4, E-value 2.6e-217 272560010637 Signal peptide predicted for BPSL2244 by SignalP 2.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.471 between residues 15 and 16; signal peptide 272560010638 TPR repeat; Region: TPR_11; pfam13414 272560010639 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560010640 binding surface 272560010641 TPR motif; other site 272560010642 Pfam match to entry PF00515 TPR, TPR Domain , score 7.7, E-value 0.44 272560010643 Pfam match to entry PF00515 TPR, TPR Domain , score 25.0, E-value 0.00011 272560010644 Signal peptide predicted for BPSL2245 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.982 between residues 21 and 22; signal peptide 272560010645 cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197 272560010646 active site 272560010647 Pfam match to entry PF00160 pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase , score 194.0, E-value 1.6e-55 272560010648 PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 272560010649 cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920 272560010650 substrate binding site [chemical binding]; other site 272560010651 Pfam match to entry PF00160 pro_isomerase, Cyclophilin type peptidyl-prolyl cis-trans isomerase , score 199.0, E-value 4.9e-57 272560010652 PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 272560010653 Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398 272560010654 putative active site [active] 272560010655 putative metal binding site [ion binding]; other site 272560010656 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 48.9, E-value 7.2e-12 272560010657 serine O-acetyltransferase; Region: cysE; TIGR01172 272560010658 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 272560010659 trimer interface [polypeptide binding]; other site 272560010660 active site 272560010661 substrate binding site [chemical binding]; other site 272560010662 CoA binding site [chemical binding]; other site 272560010663 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 7.6, E-value 5.1 272560010664 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.8, E-value 1.1 272560010665 PS00047 Histone H4 signature. 272560010666 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 20.7, E-value 0.0023 272560010667 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 8.3, E-value 4.2 272560010668 rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565 272560010669 SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307 272560010670 Pfam match to entry PF00588 SpoU_methylase, SpoU rRNA Methylase , score 70.8, E-value 1.9e-18 272560010671 IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639 272560010672 active site 272560010673 dimerization interface [polypeptide binding]; other site 272560010674 Pfam match to entry PF00459 inositol_P, Inositol monophosphatase , score 311.7, E-value 5.8e-91 272560010675 PS00629 Inositol monophosphatase signature 1. 272560010676 PS00630 Inositol monophosphatase signature 2. 272560010677 Uncharacterized protein conserved in bacteria (DUF2057); Region: DUF2057; cl11437 272560010678 Signal peptide predicted for BPSL2251 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 21 and 22; signal peptide 272560010679 DNA mismatch repair protein MutS; Provisional; Region: PRK05399 272560010680 MutS domain I; Region: MutS_I; pfam01624 272560010681 MutS domain II; Region: MutS_II; pfam05188 272560010682 MutS domain III; Region: MutS_III; pfam05192 272560010683 ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284 272560010684 Walker A/P-loop; other site 272560010685 ATP binding site [chemical binding]; other site 272560010686 Q-loop/lid; other site 272560010687 ABC transporter signature motif; other site 272560010688 Walker B; other site 272560010689 D-loop; other site 272560010690 H-loop/switch region; other site 272560010691 Pfam match to entry PF01624 MutS_N, MutS family, N-terminal DNA binding domain , score 564.4, E-value 5e-167 272560010692 Pfam match to entry PF00488 MutS_C, DNA mismatch repair proteins, mutS family , score 503.9, E-value 7.7e-149 272560010693 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010694 PS00486 DNA mismatch repair proteins mutS family signature. 272560010695 Signal peptide predicted for BPSL2253 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.904 between residues 36 and 37; signal peptide 272560010696 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; cl19519 272560010697 FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047 272560010698 Uncharacterized conserved protein [Function unknown]; Region: COG2850 272560010699 Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235 272560010700 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 14.5, E-value 0.00014 272560010701 NlpB/DapX lipoprotein; Region: Lipoprotein_18; cl19507 272560010702 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560010703 Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950 272560010704 dimer interface [polypeptide binding]; other site 272560010705 active site 272560010706 catalytic residue [active] 272560010707 Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase , score 461.6, E-value 4.4e-136 272560010708 PS00666 Dihydrodipicolinate synthetase signature 2. 272560010709 Methyltransferase domain; Region: Methyltransf_18; pfam12847 272560010710 tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927 272560010711 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 272560010712 active site 272560010713 HIGH motif; other site 272560010714 dimer interface [polypeptide binding]; other site 272560010715 KMSKS motif; other site 272560010716 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y) , score 272.5, E-value 3.6e-79 272560010717 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560010718 Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158 272560010719 Peptidase family M50; Region: Peptidase_M50; pfam02163 272560010720 active site 272560010721 putative substrate binding region [chemical binding]; other site 272560010722 6 probable transmembrane helices predicted for BPSL2261 by TMHMM2.0 at aa 12-34, 54-76, 97-119, 129-151, 172-194 and 198-220 272560010723 Telomere recombination; Region: Sua5_yciO_yrdC; cl00305 272560010724 Pfam match to entry PF01300 Sua5_yciO_yrdC, yrdC domain , score 201.1, E-value 1.2e-57 272560010725 Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613 272560010726 Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438 272560010727 active site 272560010728 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region , score 15.1, E-value 0.051 272560010729 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region , score 57.1, E-value 2.6e-14 272560010730 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560010731 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560010732 Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303 272560010733 catalytic site [active] 272560010734 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 69.7, E-value 4e-18 272560010735 PS00120 Lipases, serine active site. 272560010736 Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657 272560010737 dinuclear metal binding motif [ion binding]; other site 272560010738 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663 272560010739 Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645 272560010740 trimer interface [polypeptide binding]; other site 272560010741 putative metal binding site [ion binding]; other site 272560010742 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 6.7, E-value 6.6 272560010743 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 3.5, E-value 17 272560010744 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 3.4, E-value 4 272560010745 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 13.7, E-value 0.28 272560010746 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 18.4, E-value 0.011 272560010747 Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114 272560010748 Heat shock protein 33 (Hsp33): Cytosolic protein that acts as a molecular chaperone under oxidative conditions. In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498 272560010749 dimerization interface [polypeptide binding]; other site 272560010750 domain crossover interface; other site 272560010751 redox-dependent activation switch; other site 272560010752 Pfam match to entry PF01430 HSP33, Hsp33 protein , score 148.8, E-value 6.2e-42 272560010753 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560010754 cell division protein FtsB; Reviewed; Region: ftsB; PRK00888 272560010755 1 probable transmembrane helix predicted for BPSL2269 by TMHMM2.0 at aa 5-27 272560010756 enolase; Provisional; Region: eno; PRK00077 272560010757 Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313 272560010758 dimer interface [polypeptide binding]; other site 272560010759 metal binding site [ion binding]; metal-binding site 272560010760 substrate binding pocket [chemical binding]; other site 272560010761 Pfam match to entry PF00113 enolase, Enolase, C-terminal TIM barrel domain , score 575.9, E-value 1.7e-170 272560010762 PS00164 Enolase signature. 272560010763 Pfam match to entry PF03952 enolase_N, Enolase, N-terminal domain , score 223.8, E-value 1.6e-64 272560010764 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198 272560010765 Pfam match to entry PF00793 DAHP_synth_1, DAHP synthetase I family , score 345.8, E-value 3.1e-101 272560010766 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010767 PS00284 Serpins signature. 272560010768 CTP synthetase; Validated; Region: pyrG; PRK05380 272560010769 CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113 272560010770 Catalytic site [active] 272560010771 active site 272560010772 UTP binding site [chemical binding]; other site 272560010773 Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746 272560010774 active site 272560010775 putative oxyanion hole; other site 272560010776 catalytic triad [active] 272560010777 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 231.1, E-value 1.1e-66 272560010778 PS00442 Glutamine amidotransferases class-I active site. 272560010779 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560010780 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560010781 Lipase. Lipases are esterases that can hydrolyze long-chain acyl-triglycerides into di- and monoglycerides, glycerol, and free fatty acids at a water/lipid interface. A typical feature of lipases is "interfacial activation", the process of...; Region: Lipase; cl14883 272560010782 nucleophilic elbow; other site 272560010783 catalytic triad; other site 272560010784 PS00120 Lipases, serine active site. 272560010785 Domain of unknown function (DUF4131); Region: DUF4131; pfam13567 272560010786 DNA internalization-related competence protein ComEC/Rec2; Region: ComEC_Rec2; TIGR00361 272560010787 Competence protein; Region: Competence; pfam03772 272560010788 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 272560010789 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 14.2, E-value 0.00015 272560010790 Pfam match to entry PF03772 Competence, Competence protein , score 153.6, E-value 2.3e-43 272560010791 9 probable transmembrane helices predicted for BPSL2274 by TMHMM2.0 at aa 37-59, 64-86, 271-293, 313-335, 342-364, 379-398, 458-480, 495-517 and 538-560 272560010792 TatD like proteins; E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310 272560010793 active site 272560010794 Pfam match to entry PF01026 TatD_DNase, TatD related DNase , score 166.7, E-value 2.5e-47 272560010795 PS01091 Uncharacterized protein family UPF0006 signature 3. 272560010796 lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211 272560010797 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 272560010798 Walker A/P-loop; other site 272560010799 ATP binding site [chemical binding]; other site 272560010800 Q-loop/lid; other site 272560010801 ABC transporter signature motif; other site 272560010802 Walker B; other site 272560010803 D-loop; other site 272560010804 H-loop/switch region; other site 272560010805 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 218.8, E-value 5.2e-63 272560010806 PS00211 ABC transporters family signature. 272560010807 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010808 lipoprotein releasing system, transmembrane protein, LolC/E family; Region: lolCE; TIGR02212 272560010809 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 272560010810 FtsX-like permease family; Region: FtsX; pfam02687 272560010811 Pfam match to entry PF02687 DUF214, Predicted permease , score 135.6, E-value 5.6e-38 272560010812 4 probable transmembrane helices predicted for BPSL2277 by TMHMM2.0 at aa 24-46, 274-296, 329-351 and 378-400 272560010813 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4255 272560010814 ssDNA exonuclease RecJ; Provisional; Region: PRK11070 272560010815 DHH family; Region: DHH; pfam01368 272560010816 DHHA1 domain; Region: DHHA1; pfam02272 272560010817 Pfam match to entry PF01368 DHH, DHH family , score 173.7, E-value 2e-49 272560010818 Pfam match to entry PF02272 DHHA1, DHHA1 domain , score 44.2, E-value 1.9e-10 272560010819 peptide chain release factor 2; Validated; Region: prfB; PRK00578 272560010820 This domain is found in peptide chain release factors; Region: PCRF; smart00937 272560010821 RF-1 domain; Region: RF-1; pfam00472 272560010822 Pfam match to entry PF03462 PCRF, PCRF domain , score 105.3, E-value 7.6e-29 272560010823 Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain , score 237.8, E-value 1e-68 272560010824 lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484 272560010825 LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322 272560010826 dimer interface [polypeptide binding]; other site 272560010827 putative anticodon binding site; other site 272560010828 Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775 272560010829 motif 1; other site 272560010830 active site 272560010831 motif 2; other site 272560010832 motif 3; other site 272560010833 Pfam match to entry PF01336 tRNA_anti, OB-fold nucleic acid binding domain , score 71.7, E-value 1e-18 272560010834 Pfam match to entry PF00152 tRNA-synt_2, tRNA synthetases class II (D, K and N) , score 549.5, E-value 1.5e-162 272560010835 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560010836 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560010837 1 probable transmembrane helix predicted for BPSL2282 by TMHMM2.0 at aa 17-39 272560010838 FeS assembly protein IscX; Region: iscX_yfhJ; TIGR03412 272560010839 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560010840 catalytic loop [active] 272560010841 iron binding site [ion binding]; other site 272560010842 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 69.6, E-value 4.4e-18 272560010843 PS00190 Cytochrome c family heme-binding site signature. 272560010844 PS00814 Adrenodoxin family, iron-sulfur binding region signature. 272560010845 chaperone protein HscA; Provisional; Region: hscA; PRK05183 272560010846 Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236 272560010847 nucleotide binding site [chemical binding]; other site 272560010848 putative NEF/HSP70 interaction site [polypeptide binding]; other site 272560010849 SBD interface [polypeptide binding]; other site 272560010850 Pfam match to entry PF00012 HSP70, Hsp70 protein , score 734.9, E-value 2.2e-218 272560010851 PS01036 Heat shock hsp70 proteins family signature 3. 272560010852 PS00329 Heat shock hsp70 proteins family signature 2. 272560010853 PS00297 Heat shock hsp70 proteins family signature 1. 272560010854 co-chaperone HscB; Provisional; Region: hscB; PRK03578 272560010855 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 272560010856 HSP70 interaction site [polypeptide binding]; other site 272560010857 HSCB C-terminal oligomerization domain; Region: HSCB_C; pfam07743 272560010858 Pfam match to entry PF00226 DnaJ, DnaJ domain , score 38.2, E-value 1.2e-08 272560010859 Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400 272560010860 Pfam match to entry PF01521 HesB-like, HesB-like domain , score 199.2, E-value 4e-57 272560010861 PS01152 Hypothetical hesB/yadR/yfhF family signature. 272560010862 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 272560010863 trimerization site [polypeptide binding]; other site 272560010864 active site 272560010865 Pfam match to entry PF01592 NifU_N, NifU-like N terminal domain , score 272.5, E-value 3.6e-79 272560010866 cysteine desulfurase; Provisional; Region: PRK14012 272560010867 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560010868 catalytic residue [active] 272560010869 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 412.2, E-value 3.1e-121 272560010870 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 272560010871 iron-sulfur cluster assembly transcription factor IscR; Region: IscR; TIGR02010 272560010872 Rrf2 family protein; Region: rrf2_super; TIGR00738 272560010873 Pfam match to entry PF02082 UPF0074, Uncharacterized protein family UPF0074 , score 193.2, E-value 2.6e-55 272560010874 Low molecular weight phosphatase family; Region: LMWPc; cd00115 272560010875 active site 272560010876 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase , score 198.4, E-value 7.3e-57 272560010877 1 probable transmembrane helix predicted for BPSL2292 by TMHMM2.0 at aa 15-37 272560010878 Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139 272560010879 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 272560010880 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560010881 Domain of unknown function (DUF3390); Region: DUF3390; pfam11870 272560010882 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 15.6, E-value 0.00062 272560010883 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560010884 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 272560010885 Cysteine-rich domain; Region: CCG; pfam02754 272560010886 Cysteine-rich domain; Region: CCG; pfam02754 272560010887 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 36.2, E-value 4.8e-08 272560010888 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 62.3, E-value 6.7e-16 272560010889 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560010890 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560010891 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560010892 Predicted helix-turn-helix motif with score 1773.000, SD 5.23 at aa 32-53, sequence VSLKELAQRTELHPSTAHRILN 272560010893 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 190.8, E-value 1.4e-54 272560010894 Transposase domain (DUF772); Region: DUF772; pfam05598 272560010895 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 272560010896 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560010897 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score -2.6, E-value 0.0072 272560010898 Signal peptide predicted for BPSL2297 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.433 between residues 27 and 28; signal peptide 272560010899 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 272560010900 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191 272560010901 Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase , score 239.3, E-value 3.6e-69 272560010902 Phasin protein; Region: Phasin_2; pfam09361 272560010903 PS00017 ATP/GTP-binding site motif A (P-loop). 272560010904 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 272560010905 E3 interaction surface; other site 272560010906 lipoyl attachment site [posttranslational modification]; other site 272560010907 dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467 272560010908 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560010909 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560010910 Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852 272560010911 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain , score 167.1, E-value 2e-47 272560010912 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 298.7, E-value 4.5e-87 272560010913 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272560010914 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 96.5, E-value 3.3e-26 272560010915 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560010916 dihydrolipoamide acetyltransferase; Reviewed; Region: PRK11855 272560010917 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 272560010918 E3 interaction surface; other site 272560010919 lipoyl attachment site [posttranslational modification]; other site 272560010920 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 272560010921 E3 interaction surface; other site 272560010922 lipoyl attachment site [posttranslational modification]; other site 272560010923 e3 binding domain; Region: E3_binding; pfam02817 272560010924 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 272560010925 Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain) , score 429.8, E-value 1.6e-126 272560010926 Pfam match to entry PF02817 e3_binding, e3 binding domain , score 65.7, E-value 6.3e-17 272560010927 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 95.6, E-value 6.5e-26 272560010928 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560010929 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 97.2, E-value 2.2e-26 272560010930 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560010931 pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405 272560010932 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 272560010933 dimer interface [polypeptide binding]; other site 272560010934 TPP-binding site [chemical binding]; other site 272560010935 Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410 272560010936 Pfam match to entry PF00456 transketolase, Transketolase, thiamine diphosphate binding domain , score -130.7, E-value 1.2e-07 272560010937 PAS domain S-box; Region: sensory_box; TIGR00229 272560010938 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560010939 putative active site [active] 272560010940 heme pocket [chemical binding]; other site 272560010941 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560010942 dimer interface [polypeptide binding]; other site 272560010943 phosphorylation site [posttranslational modification] 272560010944 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560010945 ATP binding site [chemical binding]; other site 272560010946 Mg2+ binding site [ion binding]; other site 272560010947 G-X-G motif; other site 272560010948 2 probable transmembrane helices predicted for BPSL2302 by TMHMM2.0 at aa 45-67 and 292-311 272560010949 Pfam match to entry PF00989 PAS, PAS domain , score 34.8, E-value 1.3e-07 272560010950 Pfam match to entry PF00785 PAC, PAC motif , score 48.5, E-value 9.5e-12 272560010951 Pfam match to entry PF00989 PAS, PAS domain , score 6.0, E-value 0.33 272560010952 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 43.6, E-value 2.9e-10 272560010953 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 115.9, E-value 5.1e-32 272560010954 Response regulator [Signal transduction mechanisms]; Region: TtrR; COG4566 272560010955 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560010956 active site 272560010957 phosphorylation site [posttranslational modification] 272560010958 intermolecular recognition site; other site 272560010959 dimerization interface [polypeptide binding]; other site 272560010960 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560010961 DNA binding residues [nucleotide binding] 272560010962 dimerization interface [polypeptide binding]; other site 272560010963 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 138.7, E-value 6.7e-39 272560010964 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 74.1, E-value 1.9e-19 272560010965 PS00622 Bacterial regulatory proteins, luxR family signature. 272560010966 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14189 272560010967 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763 272560010968 NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080 272560010969 homodimer interface [polypeptide binding]; other site 272560010970 NADP binding site [chemical binding]; other site 272560010971 substrate binding site [chemical binding]; other site 272560010972 Pfam match to entry PF00763 THF_DHG_CYH, Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain , score 215.0, E-value 7.2e-62 272560010973 PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 272560010974 Pfam match to entry PF02882 THF_DHG_CYH_C, Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain , score 339.5, E-value 2.4e-99 272560010975 PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 272560010976 Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339 272560010977 Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456 272560010978 active site 272560010979 Zn binding site [ion binding]; other site 272560010980 Pfam match to entry PF01432 Peptidase_M3, Peptidase M3 , score 608.6, E-value 2.4e-180 272560010981 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560010982 DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586 272560010983 active site 272560010984 DNA polymerase IV; Validated; Region: PRK02406 272560010985 DNA binding site [nucleotide binding] 272560010986 Pfam match to entry PF00817 IMS, impB/mucB/samB family , score 324.4, E-value 8.3e-95 272560010987 Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223 272560010988 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560010989 putative substrate translocation pore; other site 272560010990 12 probable transmembrane helices predicted for BPSL2307 by TMHMM2.0 at aa 17-39, 54-76, 83-103, 108-130, 143-165, 170-192, 223-240, 250-272, 285-307, 322-344, 357-379 and 389-411 272560010991 Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223 272560010992 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560010993 putative substrate translocation pore; other site 272560010994 12 probable transmembrane helices predicted for BPSL2308 by TMHMM2.0 at aa 29-51, 66-88, 95-114, 124-146, 167-189, 204-226, 252-274, 284-303, 310-332, 342-364, 398-416 and 431-453 272560010995 Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013 272560010996 Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710 272560010997 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750 272560010998 [4Fe-4S] binding site [ion binding]; other site 272560010999 molybdopterin cofactor binding site [chemical binding]; other site 272560011000 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776 272560011001 molybdopterin cofactor binding site; other site 272560011002 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560011003 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 417.7, E-value 7.1e-123 272560011004 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011005 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 132.2, E-value 6e-37 272560011006 PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 272560011007 Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140 272560011008 4Fe-4S dicluster domain; Region: Fer4_11; pfam13247 272560011009 Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711 272560011010 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 9.4, E-value 0.0059 272560011011 PS00190 Cytochrome c family heme-binding site signature. 272560011012 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 8.7, E-value 0.0074 272560011013 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560011014 Nitrate reductase delta subunit [Energy production and conversion]; Region: NarJ; COG2180 272560011015 Pfam match to entry PF02613 Nitrate_red_del, Nitrate reductase delta subunit , score 145.9, E-value 4.6e-41 272560011016 Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665 272560011017 Pfam match to entry PF02665 Nitrate_red_gam, Nitrate reductase gamma subunit , score 190.1, E-value 2.4e-54 272560011018 5 probable transmembrane helices predicted for BPSL2312 by TMHMM2.0 at aa 4-26, 53-75, 90-109, 129-151 and 189-211 272560011019 Signal transduction histidine kinase, nitrate/nitrite-specific [Signal transduction mechanisms]; Region: NarQ; COG3850 272560011020 Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675 272560011021 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560011022 dimerization interface [polypeptide binding]; other site 272560011023 GAF domain; Region: GAF_2; pfam13185 272560011024 Histidine kinase; Region: HisKA_3; pfam07730 272560011025 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560011026 ATP binding site [chemical binding]; other site 272560011027 Mg2+ binding site [ion binding]; other site 272560011028 G-X-G motif; other site 272560011029 Pfam match to entry PF00672 HAMP, HAMP domain , score 60.8, E-value 1.9e-15 272560011030 1 probable transmembrane helix predicted for BPSL2313 by TMHMM2.0 at aa 150-172 272560011031 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 72.6, E-value 5.4e-19 272560011032 transcriptional regulator NarL; Provisional; Region: PRK10651 272560011033 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560011034 active site 272560011035 phosphorylation site [posttranslational modification] 272560011036 intermolecular recognition site; other site 272560011037 dimerization interface [polypeptide binding]; other site 272560011038 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560011039 DNA binding residues [nucleotide binding] 272560011040 dimerization interface [polypeptide binding]; other site 272560011041 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 136.5, E-value 3.1e-38 272560011042 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 82.4, E-value 6.1e-22 272560011043 PS00622 Bacterial regulatory proteins, luxR family signature. 272560011044 Predicted helix-turn-helix motif with score 1463.000, SD 4.17 at aa 181-202, sequence ASNKEIAREFDVAESTVKIHVQ 272560011045 Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086 272560011046 putative catalytic site [active] 272560011047 putative phosphate binding site [ion binding]; other site 272560011048 active site 272560011049 metal binding site A [ion binding]; metal-binding site 272560011050 DNA binding site [nucleotide binding] 272560011051 putative AP binding site [nucleotide binding]; other site 272560011052 putative metal binding site B [ion binding]; other site 272560011053 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 168.1, E-value 9.8e-48 272560011054 PS00728 AP endonucleases family 1 signature 3. 272560011055 nitrogen regulation protein NR(I); Region: ntrC; TIGR01818 272560011056 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560011057 active site 272560011058 phosphorylation site [posttranslational modification] 272560011059 intermolecular recognition site; other site 272560011060 dimerization interface [polypeptide binding]; other site 272560011061 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560011062 Walker A motif; other site 272560011063 ATP binding site [chemical binding]; other site 272560011064 Walker B motif; other site 272560011065 arginine finger; other site 272560011066 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560011067 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 48.7, E-value 8.6e-12 272560011068 Predicted helix-turn-helix motif with score 1720.000, SD 5.05 at aa 484-505, sequence GRKVEAAERLGIGRNTITRKIQ 272560011069 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560011070 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 461.6, E-value 4.4e-136 272560011071 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560011072 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560011073 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 119.1, E-value 5.5e-33 272560011074 Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852 272560011075 PAS domain; Region: PAS; smart00091 272560011076 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560011077 dimer interface [polypeptide binding]; other site 272560011078 phosphorylation site [posttranslational modification] 272560011079 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560011080 ATP binding site [chemical binding]; other site 272560011081 Mg2+ binding site [ion binding]; other site 272560011082 G-X-G motif; other site 272560011083 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 101.6, E-value 1e-27 272560011084 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 63.4, E-value 3.1e-16 272560011085 glutamine synthetase; Provisional; Region: glnA; PRK09469 272560011086 Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951 272560011087 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 272560011088 PS00182 Glutamine synthetase class-I adenylation site. 272560011089 Pfam match to entry PF00120 gln-synt, Glutamine synthetase, catalytic domain , score 561.4, E-value 3.9e-166 272560011090 PS00181 Glutamine synthetase ATP-binding region signature. 272560011091 Pfam match to entry PF03951 gln-synt_N, Glutamine synthetase, beta-Grasp domain , score 156.8, E-value 2.3e-44 272560011092 PS00180 Glutamine synthetase signature 1. 272560011093 Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522 272560011094 active site residue [active] 272560011095 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058 272560011096 Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885 272560011097 putative MPT binding site; other site 272560011098 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain , score 31.9, E-value 5.4e-09 272560011099 Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264 272560011100 7 probable transmembrane helices predicted for BPSL2321 by TMHMM2.0 at aa 50-72, 85-107, 111-133, 154-176, 181-200, 227-249 and 259-281 272560011101 Sterol desaturase [Lipid metabolism]; Region: ERG3; COG3000 272560011102 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; pfam04116 272560011103 4 probable transmembrane helices predicted for BPSL2322 by TMHMM2.0 at aa 44-63, 84-106, 131-153 and 190-212 272560011104 Signal peptide predicted for BPSL2323 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.995 between residues 25 and 26; signal peptide 272560011105 PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866 272560011106 WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200 272560011107 ATP-dependent helicase HrpA; Region: DEAH_box_HrpA; TIGR01967 272560011108 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560011109 ATP binding site [chemical binding]; other site 272560011110 putative Mg++ binding site [ion binding]; other site 272560011111 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560011112 nucleotide binding region [chemical binding]; other site 272560011113 ATP-binding site [chemical binding]; other site 272560011114 Helicase associated domain (HA2); Region: HA2; pfam04408 272560011115 Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717 272560011116 Domain of unknown function (DUF3418); Region: DUF3418; pfam11898 272560011117 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 54.3, E-value 1.7e-13 272560011118 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011119 N-acetylglutamate synthase; Validated; Region: PRK05279 272560011120 AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237 272560011121 putative feedback inhibition sensing region; other site 272560011122 putative nucleotide binding site [chemical binding]; other site 272560011123 putative substrate binding site [chemical binding]; other site 272560011124 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560011125 Coenzyme A binding pocket [chemical binding]; other site 272560011126 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 53.7, E-value 2.6e-13 272560011127 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 54.3, E-value 1.8e-13 272560011128 oxidative damage protection protein; Provisional; Region: PRK05408 272560011129 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560011130 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560011131 putative substrate translocation pore; other site 272560011132 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 76.9, E-value 2.6e-20 272560011133 12 probable transmembrane helices predicted for BPSL2327 by TMHMM2.0 at aa 21-43, 63-85, 97-119, 129-151, 163-185, 200-219, 250-269, 284-306, 313-335, 340-362, 375-397 and 407-429 272560011134 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560011135 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 221.4, E-value 8.7e-64 272560011136 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560011137 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560011138 active site 272560011139 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 165.3, E-value 6.5e-47 272560011140 PS00073 Acyl-CoA dehydrogenases signature 2. 272560011141 PS00215 Mitochondrial energy transfer proteins signature. 272560011142 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 15.2, E-value 9.3e-08 272560011143 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 272560011144 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560011145 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560011146 dimerization interface [polypeptide binding]; other site 272560011147 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 102.7, E-value 4.7e-28 272560011148 Predicted helix-turn-helix motif with score 1247.000, SD 3.43 at aa 16-37, sequence LHFGRAAKRLFISQPALSFDIR 272560011149 PS00044 Bacterial regulatory proteins, lysR family signature. 272560011150 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 166.2, E-value 3.7e-47 272560011151 Protein of unknown function (DUF2971); Region: DUF2971; pfam11185 272560011152 Plasmid stabilization system protein [General function prediction only]; Region: ParE; COG3668 272560011153 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560011154 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560011155 inhibitor-cofactor binding pocket; inhibition site 272560011156 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560011157 catalytic residue [active] 272560011158 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 335.4, E-value 4.1e-98 272560011159 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560011160 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 272560011161 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 272560011162 Pfam match to entry PF00120 gln-synt, Glutamine synthetase, catalytic domain , score 370.3, E-value 1.3e-108 272560011163 Pfam match to entry PF03951 gln-synt_N, Glutamine synthetase, beta-Grasp domain , score 9.8, E-value 0.0083 272560011164 Peptidase C26; Region: Peptidase_C26; pfam07722 272560011165 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 272560011166 catalytic triad [active] 272560011167 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score -27.9, E-value 2.2e-05 272560011168 N-formylglutamate amidohydrolase; Region: FGase; cl01522 272560011169 N-formimino-L-glutamate deiminase; Validated; Region: PRK09229 272560011170 Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_E; cd01313 272560011171 active site 272560011172 Pfam match to entry PF01685 ATZ_TRZ, Chlorohydrolase , score 133.5, E-value 2.6e-37 272560011173 imidazolonepropionase; Validated; Region: PRK09356 272560011174 Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296 272560011175 active site 272560011176 PS00296 Chaperonins cpn60 signature. 272560011177 HutD; Region: HutD; pfam05962 272560011178 urocanate hydratase; Provisional; Region: PRK05414 272560011179 Pfam match to entry PF01175 Urocanase, Urocanase , score 1267.8, E-value 0 272560011180 PS01233 Urocanase active site. 272560011181 histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018 272560011182 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560011183 DNA-binding site [nucleotide binding]; DNA binding site 272560011184 UTRA domain; Region: UTRA; pfam07702 272560011185 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 89.7, E-value 3.7e-24 272560011186 Predicted helix-turn-helix motif with score 1354.000, SD 3.80 at aa 29-50, sequence PSENELAREFKVARMTVNRALR 272560011187 Aromatic amino acid lyase; Region: Lyase_aromatic; pfam00221 272560011188 Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332 272560011189 active sites [active] 272560011190 tetramer interface [polypeptide binding]; other site 272560011191 Pfam match to entry PF00221 PAL, Phenylalanine and histidine ammonia-lyase , score 777.8, E-value 2.8e-231 272560011192 PS00488 Phenylalanine and histidine ammonia-lyases signature. 272560011193 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 272560011194 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 272560011195 Pfam match to entry PF01648 ACPS, 4'-phosphopantetheinyl transferase superfamily , score 6.3, E-value 0.0012 272560011196 Predicted alpha/beta hydrolase [General function prediction only]; Region: COG4757 272560011197 DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188 272560011198 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560011199 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560011200 DNA binding residues [nucleotide binding] 272560011201 dimerization interface [polypeptide binding]; other site 272560011202 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 59.4, E-value 5.1e-15 272560011203 PS00622 Bacterial regulatory proteins, luxR family signature. 272560011204 Pfam match to entry PF03472 Autoind_bind, Autoinducer binding domain , score 123.5, E-value 2.5e-34 272560011205 Pseudogene. Similar to Escherichia coli, and Escherichia coli O157:H7 adenylylsulfate kinase CysC SWALL:CYSC_ECOLI (SWALL:P23846) (200 aa) fasta scores: E(): 9e-23, 49.37% id in 160 aa, and to Pseudomonas aeruginosa adenylylsulfate kinase CysC or pa1393 SWALL:CYC1_PSEAE (SWALL:P57702) (196 aa) fasta scores: E(): 2.5e-25, 45.69% id in 186 aa. CDS is extended at the C-terminus in comparison to orthologues. CDS contains 2 frameshift mutations after residues 19 and 29, and a nonsense mutation (opal) after codon 11;adenylylsulfate kinase (pseudogene) 272560011206 Pfam match to entry PF01583 APS_kinase, Adenylylsulfate kinase , score 278.0, E-value 8.1e-81 272560011207 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011208 Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415 272560011209 DNA photolyase; Region: DNA_photolyase; pfam00875 272560011210 FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441 272560011211 Pfam match to entry PF03441 FAD_binding_7, FAD binding domain of DNA photolyase , score 407.9, E-value 6.5e-120 272560011212 PS00691 DNA photolyases class 1 signature 2. 272560011213 Pfam match to entry PF00875 DNA_photolyase, DNA photolyase , score 134.1, E-value 1.6e-37 272560011214 Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes...; Region: Alkane-hydroxylase; cd03512 272560011215 Di-iron ligands [ion binding]; other site 272560011216 6 probable transmembrane helices predicted for BPSL2350 by TMHMM2.0 at aa 17-39, 43-65, 86-108, 112-134, 235-257 and 330-352 272560011217 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 138.5, E-value 7.8e-39 272560011218 Signal peptide predicted for BPSL2351 by SignalP 2.0 HMM (Signal peptide probabilty 0.987) with cleavage site probability 0.772 between residues 20 and 21; signal peptide 272560011219 Nitric oxide reductase large subunit [Inorganic ion transport and metabolism]; Region: NorB; COG3256 272560011220 Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115 272560011221 14 probable transmembrane helices predicted for BPSL2351 by TMHMM2.0 at aa 7-26, 229-251, 286-308, 334-356, 368-387, 413-435, 447-469, 484-506, 519-541, 546-568, 589-611, 631-653, 666-688 and 717-739 272560011222 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560011223 Pseudogene. Similar to Thermoplasma volcanium hypothetical protein tv1419 or tvg1466613 SWALL:Q978J6 (EMBL:AP000996) (100 aa) fasta scores: E(): 7.2e-13, 46.06% id in 89 aa, and to the C-terminal region of Corynebacterium glutamicum aromatic ring hydroxylating enzyme cgl1559 SWALL:Q8NQ80 (EMBL:AP005278) (141 aa) fasta scores: E(): 2.8e-11, 40.56% id in 106 aa. CDS contains a frameshift after codon 65;conserved hypothetical protein (pseudogene) 272560011224 Pfam match to entry PF01883 DUF59, Domain of unknown function DUF59 , score 44.2, E-value 2e-10 272560011225 12 probable transmembrane helices predicted for BPSL2354 by TMHMM2.0 at aa 20-42, 52-69, 76-98, 103-122, 127-149, 153-170, 183-205, 209-226, 239-261, 276-298, 311-330 and 340-362 272560011226 NnrS protein; Region: NnrS; pfam05940 272560011227 12 probable transmembrane helices predicted for BPSL2355 by TMHMM2.0 at aa 64-86, 101-123, 135-152, 156-178, 185-207, 222-241, 254-276, 280-299, 312-334, 338-357, 377-399 and 403-425 272560011228 Anaerobic ribonucleoside-triphosphate reductase; Region: NRDD; pfam13597 272560011229 Class III ribonucleotide reductase; Region: RNR_III; cd01675 272560011230 effector binding site; other site 272560011231 active site 272560011232 Zn binding site [ion binding]; other site 272560011233 Glycine radical; Region: Gly_radical; cl19199 272560011234 anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG2; TIGR02495 272560011235 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560011236 FeS/SAM binding site; other site 272560011237 Pfam match to entry PF02143 Radical_activat, Radical activating enzyme , score 50.0, E-value 3.4e-12 272560011238 PS00190 Cytochrome c family heme-binding site signature. 272560011239 DGC domain; Region: DGC; pfam08859 272560011240 SCP-2 sterol transfer family; Region: SCP2; cl01225 272560011241 putative protease; Provisional; Region: PRK15447 272560011242 Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826 272560011243 Pfam match to entry PF01136 Peptidase_U32, Peptidase U32 , score 391.1, E-value 7e-115 272560011244 PS01276 Peptidase U32 signature. 272560011245 Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070 272560011246 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 272560011247 FMN binding site [chemical binding]; other site 272560011248 substrate binding site [chemical binding]; other site 272560011249 putative catalytic residue [active] 272560011250 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase , score 59.5, E-value 4.7e-15 272560011251 PS00912 Dihydroorotate dehydrogenase signature 2. 272560011252 12 probable transmembrane helices predicted for BPSL2364 by TMHMM2.0 at aa 35-57, 67-89, 102-124, 134-156, 176-198, 208-230, 243-265, 275-295, 308-330, 335-357, 395-414 and 419-438 272560011253 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560011254 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560011255 ligand binding site [chemical binding]; other site 272560011256 flexible hinge region; other site 272560011257 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 272560011258 Predicted helix-turn-helix motif with score 1483.000, SD 4.24 at aa 180-201, sequence TGKKAIASRLNLTPEHFSRVLR 272560011259 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 74.7, E-value 1.2e-19 272560011260 coproporphyrinogen III oxidase; Provisional; Region: PRK09249 272560011261 Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729 272560011262 HemN C-terminal domain; Region: HemN_C; pfam06969 272560011263 Pfam match to entry PF02473 Coprogen_an_ox, Oxygen-independent Coproporphyrinogen III oxidase , score 475.6, E-value 2.6e-140 272560011264 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560011265 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560011266 dimerization interface [polypeptide binding]; other site 272560011267 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560011268 dimer interface [polypeptide binding]; other site 272560011269 putative CheW interface [polypeptide binding]; other site 272560011270 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 310.0, E-value 1.9e-90 272560011271 Pfam match to entry PF00672 HAMP, HAMP domain , score 29.6, E-value 4.6e-06 272560011272 2 probable transmembrane helices predicted for BPSL2367 by TMHMM2.0 at aa 23-45 and 315-337 272560011273 NnrS protein; Region: NnrS; pfam05940 272560011274 10 probable transmembrane helices predicted for BPSL2368 by TMHMM2.0 at aa 34-56, 71-93, 100-122, 127-149, 156-178, 188-210, 279-301, 311-333, 346-363 and 373-395 272560011275 cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814 272560011276 Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458 272560011277 Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051) , score 432.7, E-value 2.1e-127 272560011278 FeS assembly ATPase SufC; Region: sufC; TIGR01978 272560011279 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217 272560011280 Walker A/P-loop; other site 272560011281 ATP binding site [chemical binding]; other site 272560011282 Q-loop/lid; other site 272560011283 ABC transporter signature motif; other site 272560011284 Walker B; other site 272560011285 D-loop; other site 272560011286 H-loop/switch region; other site 272560011287 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 109.3, E-value 4.9e-30 272560011288 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011289 PS00211 ABC transporters family signature. 272560011290 FeS assembly protein SufD; Region: sufD; TIGR01981 272560011291 Pfam match to entry PF01458 UPF0051, Uncharacterized protein family (UPF0051) , score -5.0, E-value 4.9e-08 272560011292 Signal peptide predicted for BPSL2372 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.552 between residues 21 and 22; signal peptide 272560011293 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 272560011294 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560011295 catalytic residue [active] 272560011296 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 33.3, E-value 3.6e-10 272560011297 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 272560011298 Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664 272560011299 trimerization site [polypeptide binding]; other site 272560011300 active site 272560011301 Pfam match to entry PF01592 NifU_N, NifU-like N terminal domain , score 80.4, E-value 2.4e-21 272560011302 probable FeS assembly SUF system protein SufT; Region: FeS_long_SufT; TIGR03406 272560011303 Pfam match to entry PF01883 DUF59, Domain of unknown function DUF59 , score 76.1, E-value 4.7e-20 272560011304 PS00092 N-6 Adenine-specific DNA methylases signature. 272560011305 Uncharacterized conserved protein (DUF2249); Region: DUF2249; cl17719 272560011306 Predicted transcriptional regulator [Transcription]; Region: COG1959 272560011307 Rrf2 family protein; Region: rrf2_super; TIGR00738 272560011308 Pfam match to entry PF02082 UPF0074, Uncharacterized protein family UPF0074 , score 127.8, E-value 1.3e-35 272560011309 Predicted helix-turn-helix motif with score 1623.000, SD 4.71 at aa 28-49, sequence ITIAELAERHDVSKNHLTKIVN 272560011310 Hemerythrin; Region: Hemerythrin; cd12107 272560011311 Fe binding site [ion binding]; other site 272560011312 Signal peptide predicted for BPSL2378 by SignalP 2.0 HMM (Signal peptide probabilty 0.829) with cleavage site probability 0.327 between residues 29 and 30; signal peptide 272560011313 cytochrome o ubiquinol oxidase subunit II; Region: CyoA; TIGR01433 272560011314 The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212 272560011315 COX Aromatic Rich Motif; Region: COX_ARM; pfam06481 272560011316 3 probable transmembrane helices predicted for BPSL2378 by TMHMM2.0 at aa 12-30, 45-67 and 86-108 272560011317 Pfam match to entry PF00116 COX2, Cytochrome C oxidase subunit II, periplasmic domain , score 18.4, E-value 3.2e-05 272560011318 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 272560011319 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 272560011320 D-pathway; other site 272560011321 Putative ubiquinol binding site [chemical binding]; other site 272560011322 Low-spin heme (heme b) binding site [chemical binding]; other site 272560011323 Putative water exit pathway; other site 272560011324 Binuclear center (heme o3/CuB) [ion binding]; other site 272560011325 K-pathway; other site 272560011326 Putative proton exit pathway; other site 272560011327 15 probable transmembrane helices predicted for BPSL2379 by TMHMM2.0 at aa 15-37, 57-79, 104-126, 139-161, 190-212, 232-254, 274-296, 309-331, 346-368, 380-402, 417-439, 456-478, 493-512, 587-609 and 613-632 272560011328 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score 870.6, E-value 3.2e-259 272560011329 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560011330 Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863 272560011331 Subunit I/III interface [polypeptide binding]; other site 272560011332 Subunit III/IV interface [polypeptide binding]; other site 272560011333 Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III , score -169.2, E-value 4.1e-06 272560011334 5 probable transmembrane helices predicted for BPSL2380 by TMHMM2.0 at aa 22-44, 64-86, 93-110, 135-157 and 178-200 272560011335 cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847 272560011336 Pfam match to entry PF03626 COX4_pro, Prokaryotic Cytochrome C oxidase subunit IV , score 125.3, E-value 7.5e-35 272560011337 3 probable transmembrane helices predicted for BPSL2381 by TMHMM2.0 at aa 20-42, 47-69 and 79-101 272560011338 The membrane fatty acid desaturase (Membrane_FADS)-like CD includes membrane FADSs, alkane hydroxylases, beta carotene ketolases (CrtW-like), hydroxylases (CrtR-like), and other related proteins. They are present in all groups of organisms with the...; Region: Membrane-FADS-like; cl00615 272560011339 putative di-iron ligands [ion binding]; other site 272560011340 5 probable transmembrane helices predicted for BPSL2382 by TMHMM2.0 at aa 62-84, 88-110, 226-243, 253-275 and 295-317 272560011341 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 56.9, E-value 2.8e-14 272560011342 Signal peptide predicted for BPSL2383 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 26 and 27; signal peptide 272560011343 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 272560011344 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560011345 substrate binding pocket [chemical binding]; other site 272560011346 membrane-bound complex binding site; other site 272560011347 hinge residues; other site 272560011348 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 286.9, E-value 1.7e-83 272560011349 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560011350 Probable gene remnant. Similar to the C-terminal regions of Escherichia coli, and Escherichia coli O157:H7 glutathione S-transferase Gst SWALL:GT_ECOLI (SWALL:P39100) (201 aa) fasta scores: E(): 1.5e-14, 37.5% id in 152 aa, and Ralstonia solanacearum probable glutathione S-transferase rsc3309 or rs02538 SWALL:Q8XU84 (EMBL:AL646074) (202 aa) fasta scores: E(): 2.4e-27, 55.55% id in 144 aa; glutathione S-transferase (fragment) 272560011351 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 54.9, E-value 1.1e-13 272560011352 Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855 272560011353 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 272560011354 putative active site [active] 272560011355 Zn binding site [ion binding]; other site 272560011356 succinylarginine dihydrolase; Provisional; Region: PRK13281 272560011357 N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095 272560011358 NAD(P) binding site [chemical binding]; other site 272560011359 catalytic residues [active] 272560011360 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 306.8, E-value 1.7e-89 272560011361 PS00070 Aldehyde dehydrogenases cysteine active site. 272560011362 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560011363 arginine N-succinyltransferase; Region: arg_catab_AstA; TIGR03244 272560011364 arginine/ornithine succinyltransferase, alpha subunit; Region: arg_AOST_alph; TIGR03245 272560011365 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560011366 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560011367 inhibitor-cofactor binding pocket; inhibition site 272560011368 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560011369 catalytic residue [active] 272560011370 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 551.6, E-value 3.4e-163 272560011371 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560011372 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560011373 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 272560011374 conserved cys residue [active] 272560011375 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560011376 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560011377 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 44.9, E-value 1.2e-10 272560011378 PS00041 Bacterial regulatory proteins, araC family signature. 272560011379 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 41.1, E-value 1.6e-09 272560011380 Predicted helix-turn-helix motif with score 1646.000, SD 4.79 at aa 239-260, sequence LTTDEIAGLVGVSRRQLERLFR 272560011381 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 272560011382 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560011383 Walker A/P-loop; other site 272560011384 ATP binding site [chemical binding]; other site 272560011385 Q-loop/lid; other site 272560011386 ABC transporter signature motif; other site 272560011387 Walker B; other site 272560011388 D-loop; other site 272560011389 H-loop/switch region; other site 272560011390 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 219.4, E-value 3.5e-63 272560011391 PS00211 ABC transporters family signature. 272560011392 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011393 ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160 272560011394 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560011395 dimer interface [polypeptide binding]; other site 272560011396 conserved gate region; other site 272560011397 putative PBP binding loops; other site 272560011398 ABC-ATPase subunit interface; other site 272560011399 5 probable transmembrane helices predicted for BPSL2393 by TMHMM2.0 at aa 22-44, 64-86, 106-128, 160-182 and 197-219 272560011400 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 38.4, E-value 1e-08 272560011401 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560011402 Predicted helix-turn-helix motif with score 1141.000, SD 3.07 at aa 130-151, sequence HGEVEAARAYGMSPFTMYRRVI 272560011403 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 272560011404 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560011405 dimer interface [polypeptide binding]; other site 272560011406 conserved gate region; other site 272560011407 putative PBP binding loops; other site 272560011408 ABC-ATPase subunit interface; other site 272560011409 6 probable transmembrane helices predicted for BPSL2394 by TMHMM2.0 at aa 13-35, 45-64, 77-99, 114-132, 179-201 and 214-236 272560011410 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 56.2, E-value 4.7e-14 272560011411 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011412 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560011413 SmpA / OmlA family; Region: SmpA_OmlA; cl19285 272560011414 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560011415 Uncharacterized protein family (UPF0104); Region: UPF0104; cl04219 272560011416 5 probable transmembrane helices predicted for BPSL2396 by TMHMM2.0 at aa 7-26, 31-53, 118-140, 144-166 and 212-234 272560011417 Catalytic domain of glycoside hydrolase (GH) families 38 and 57, lactam utilization protein LamB/YcsF family proteins, YdjC-family proteins, and similar proteins; Region: GH38-57_N_LamB_YdjC_SF; cl17191 272560011418 hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471 272560011419 B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293 272560011420 B12 binding site [chemical binding]; other site 272560011421 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560011422 FeS/SAM binding site; other site 272560011423 Glucosylceramide synthase catalyzes the first glycosylation step of glycosphingolipid synthesis; Region: Glucosylceramide_synthase; cd02520 272560011424 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560011425 ligand binding site; other site 272560011426 3 probable transmembrane helices predicted for BPSL2399 by TMHMM2.0 at aa 10-32, 284-306 and 311-330 272560011427 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 25.1, E-value 0.00011 272560011428 probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858 272560011429 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cd00347 272560011430 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score 151.8, E-value 7.6e-43 272560011431 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560011432 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560011433 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 69.5, E-value 4.5e-18 272560011434 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score -58.6, E-value 0.0051 272560011435 Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173 272560011436 dimer interface [polypeptide binding]; other site 272560011437 pyridoxal binding site [chemical binding]; other site 272560011438 ATP binding site [chemical binding]; other site 272560011439 Weakly similar to the C-terminal region of Burkholderia glumae hypothetical protein SWALL:Q7X299 (EMBL:AB112549) (205 aa) fasta scores: E(): 1.5, 28.31% id in 166 aa. CDS contains a possible frameshift after codon 27. Without the framesift there is no available translational start site for this CDS;hypothetical protein (pseudogene) 272560011440 Signal peptide predicted for BPSL2403 by SignalP 2.0 HMM (Signal peptide probabilty 0.774) with cleavage site probability 0.258 between residues 34 and 35; signal peptide 272560011441 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 272560011442 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560011443 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560011444 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560011445 Signal peptide predicted for BPSL2404 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.971 between residues 26 and 27; signal peptide 272560011446 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560011447 dimerization interface [polypeptide binding]; other site 272560011448 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560011449 ligand binding site [chemical binding]; other site 272560011450 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560011451 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 8.0, E-value 8.6e-06 272560011452 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 272560011453 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560011454 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -41.0, E-value 9.4e-06 272560011455 Predicted membrane protein (DUF2214); Region: DUF2214; pfam09980 272560011456 4 probable transmembrane helices predicted for BPSL2406 by TMHMM2.0 at aa 4-23, 50-69, 89-108 and 129-151 272560011457 3 probable transmembrane helices predicted for BPSL2407 by TMHMM2.0 at aa 28-50, 71-93 and 98-120 272560011458 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560011459 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 272560011460 putative ADP-binding pocket [chemical binding]; other site 272560011461 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 87.0, E-value 2.5e-23 272560011462 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 272560011463 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560011464 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560011465 Walker A/P-loop; other site 272560011466 ATP binding site [chemical binding]; other site 272560011467 Q-loop/lid; other site 272560011468 ABC transporter signature motif; other site 272560011469 Walker B; other site 272560011470 D-loop; other site 272560011471 H-loop/switch region; other site 272560011472 5 probable transmembrane helices predicted for BPSL2409 by TMHMM2.0 at aa 37-59, 74-96, 153-175, 179-198 and 263-285 272560011473 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 22.7, E-value 3.4e-05 272560011474 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 230.2, E-value 1.9e-66 272560011475 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011476 PS00211 ABC transporters family signature. 272560011477 Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788 272560011478 alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400 272560011479 active site 272560011480 homotetramer interface [polypeptide binding]; other site 272560011481 Pfam match to entry PF00982 Glyco_transf_20, Glycosyltransferase 20 , score 510.1, E-value 1.1e-150 272560011482 trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105 272560011483 HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484 272560011484 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560011485 active site 272560011486 motif I; other site 272560011487 motif II; other site 272560011488 Pfam match to entry PF02358 Trehalose_PPase, Trehalose-phosphatase , score 197.1, E-value 1.7e-56 272560011489 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560011490 Cu(I) binding site [ion binding]; other site 272560011491 Pfam match to entry PF02630 SCO1-SenC, SCO1/SenC , score 96.5, E-value 3.3e-26 272560011492 Signal peptide predicted for BPSL2413 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.938 between residues 22 and 23; signal peptide 272560011493 Protein of unknown function (DUF461); Region: DUF461; pfam04314 272560011494 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678 272560011495 7 probable transmembrane helices predicted for BPSL2414 by TMHMM2.0 at aa 10-29, 42-59, 79-101, 122-141, 156-175, 188-210 and 236-258 272560011496 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560011497 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 25.9, E-value 6e-05 272560011498 Pirin-related protein [General function prediction only]; Region: COG1741 272560011499 Pirin; Region: Pirin; pfam02678 272560011500 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 272560011501 Pfam match to entry PF02678 DUF209, Uncharacterized BCR, YhhW family COG1741 , score -29.3, E-value 2.8e-09 272560011502 LysR family transcriptional regulator; Provisional; Region: PRK14997 272560011503 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560011504 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473 272560011505 putative effector binding pocket; other site 272560011506 putative dimerization interface [polypeptide binding]; other site 272560011507 PS00228 Tubulin-beta mRNA autoregulation signal. 272560011508 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 63.5, E-value 3e-16 272560011509 Predicted helix-turn-helix motif with score 1026.000, SD 2.68 at aa 17-38, sequence GGFAPAGRALNLPKSKLSRRIA 272560011510 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 124.6, E-value 1.2e-34 272560011511 GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956 272560011512 Pfam match to entry PF01590 GAF, GAF domain , score 22.8, E-value 4.1e-06 272560011513 PS01320 Uncharacterized protein family UPF0067 signature. 272560011514 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453 272560011515 Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase , score 142.1, E-value 6.4e-40 272560011516 4 probable transmembrane helices predicted for BPSL2419 by TMHMM2.0 at aa 21-43, 100-122, 143-165 and 185-207 272560011517 PS00379 CDP-alcohol phosphatidyltransferases signature. 272560011518 excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558 272560011519 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 272560011520 GIY-YIG motif/motif A; other site 272560011521 active site 272560011522 catalytic site [active] 272560011523 putative DNA binding site [nucleotide binding]; other site 272560011524 metal binding site [ion binding]; metal-binding site 272560011525 UvrB/uvrC motif; Region: UVR; pfam02151 272560011526 UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459 272560011527 Helix-hairpin-helix domain; Region: HHH_5; pfam14520 272560011528 Pfam match to entry PF00633 HHH, Helix-hairpin-helix motif , score 30.3, E-value 2.8e-06 272560011529 Pfam match to entry PF02151 UVR, UvrB/uvrC motif , score 31.9, E-value 9.5e-07 272560011530 Pfam match to entry PF01541 Exci_endo_N, Endo/excinuclease amino terminal domain , score 115.7, E-value 5.6e-32 272560011531 Uncharacterized protein conserved in bacteria (DUF2331); Region: DUF2331; pfam10093 272560011532 elongation factor P; Validated; Region: PRK00529 272560011533 Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207 272560011534 S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470 272560011535 RNA binding site [nucleotide binding]; other site 272560011536 S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794 272560011537 RNA binding site [nucleotide binding]; other site 272560011538 Pfam match to entry PF01132 EFP, Elongation factor P (EF-P) , score 215.3, E-value 5.8e-62 272560011539 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560011540 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560011541 active site 272560011542 phosphorylation site [posttranslational modification] 272560011543 intermolecular recognition site; other site 272560011544 dimerization interface [polypeptide binding]; other site 272560011545 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560011546 Walker A motif; other site 272560011547 ATP binding site [chemical binding]; other site 272560011548 Walker B motif; other site 272560011549 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560011550 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 120.6, E-value 1.9e-33 272560011551 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 249.2, E-value 3.6e-72 272560011552 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 53.5, E-value 3.1e-13 272560011553 Predicted helix-turn-helix motif with score 1795.000, SD 5.30 at aa 439-460, sequence GTRHRAATLLGISPKTLYNKLQ 272560011554 beta-hexosaminidase; Provisional; Region: PRK05337 272560011555 Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase 3 N terminal domain , score 135.9, E-value 4.6e-38 272560011556 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560011557 4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070 272560011558 Pfam match to entry PF01648 ACPS, 4'-phosphopantetheinyl transferase superfamily , score 77.9, E-value 1.3e-20 272560011559 Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003 272560011560 active site 272560011561 hydrophilic channel; other site 272560011562 dimerization interface [polypeptide binding]; other site 272560011563 catalytic residues [active] 272560011564 active site lid [active] 272560011565 Pfam match to entry PF03740 PdxJ, Pyridoxal phosphate biosynthesis protein PdxJ , score 471.3, E-value 5.2e-139 272560011566 DNA repair protein RecO; Reviewed; Region: recO; PRK00085 272560011567 Recombination protein O N terminal; Region: RecO_N; pfam11967 272560011568 Recombination protein O C terminal; Region: RecO_C; pfam02565 272560011569 Pfam match to entry PF02565 RecO, Recombination protein O , score 49.0, E-value 7e-12 272560011570 GTPase Era; Reviewed; Region: era; PRK00089 272560011571 E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163 272560011572 G1 box; other site 272560011573 GTP/Mg2+ binding site [chemical binding]; other site 272560011574 Switch I region; other site 272560011575 G2 box; other site 272560011576 Switch II region; other site 272560011577 G3 box; other site 272560011578 G4 box; other site 272560011579 G5 box; other site 272560011580 KH domain; Region: KH_2; pfam07650 272560011581 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011582 ribonuclease III; Provisional; Region: PRK14718 272560011583 RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593 272560011584 dimerization interface [polypeptide binding]; other site 272560011585 active site 272560011586 metal binding site [ion binding]; metal-binding site 272560011587 Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048 272560011588 Pfam match to entry PF00035 dsrm, Double-stranded RNA binding motif , score 72.0, E-value 8.3e-19 272560011589 Pfam match to entry PF00636 Ribonuclease_3, RNase3 domain , score 149.2, E-value 4.7e-42 272560011590 PS00517 Ribonuclease III family signature. 272560011591 signal peptidase I; Provisional; Region: PRK10861 272560011592 The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530 272560011593 Catalytic site [active] 272560011594 conjugal transfer pilin processing protease TraF; Provisional; Region: PRK13838 272560011595 Pfam match to entry PF00461 Peptidase_S26, Signal peptidase I , score 212.0, E-value 5.9e-61 272560011596 PS00761 Signal peptidases I signature 3. 272560011597 PS00760 Signal peptidases I lysine active site. 272560011598 PS00501 Signal peptidases I serine active site. 272560011599 2 probable transmembrane helices predicted for BPSL2430 by TMHMM2.0 at aa 4-26 and 72-94 272560011600 GTP-binding protein LepA; Provisional; Region: PRK05433 272560011601 LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890 272560011602 G1 box; other site 272560011603 putative GEF interaction site [polypeptide binding]; other site 272560011604 GTP/Mg2+ binding site [chemical binding]; other site 272560011605 Switch I region; other site 272560011606 G2 box; other site 272560011607 G3 box; other site 272560011608 Switch II region; other site 272560011609 G4 box; other site 272560011610 G5 box; other site 272560011611 lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699 272560011612 Elongation Factor G, domain II; Region: EFG_II; pfam14492 272560011613 lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane. LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709 272560011614 GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421 272560011615 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus , score 129.6, E-value 3.8e-36 272560011616 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 43.3, E-value 3.5e-10 272560011617 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 241.7, E-value 6.5e-70 272560011618 PS00301 GTP-binding elongation factors signature. 272560011619 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011620 Glutaredoxin-like domain (DUF836); Region: DUF836; pfam05768 272560011621 periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037 272560011622 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 272560011623 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560011624 protein binding site [polypeptide binding]; other site 272560011625 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560011626 protein binding site [polypeptide binding]; other site 272560011627 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 15.8, E-value 0.0018 272560011628 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 52.1, E-value 8.2e-13 272560011629 Pfam match to entry PF00089 trypsin, Trypsin , score 75.0, E-value 1e-19 272560011630 Signal peptide predicted for BPSL2434 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.987 between residues 35 and 36; signal peptide 272560011631 Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl19192 272560011632 Pfam match to entry PF03888 MucB_RseB, MucB/RseB family , score 77.2, E-value 2.1e-20 272560011633 Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872 272560011634 1 probable transmembrane helix predicted for BPSL2435 by TMHMM2.0 at aa 111-130 272560011635 Pfam match to entry PF03872 RseA_N, Anti sigma-E protein RseA, N-terminal domain , score 23.4, E-value 1.7e-06 272560011636 RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939 272560011637 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560011638 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560011639 DNA binding residues [nucleotide binding] 272560011640 Predicted helix-turn-helix motif with score 1461.000, SD 4.16 at aa 156-177, sequence LSYEEIAEMMGCPIGTVRSRIF 272560011641 PS01063 Sigma-70 factors ECF subfamily signature. 272560011642 2 probable transmembrane helices predicted for BPSL2437 by TMHMM2.0 at aa 21-40 and 45-64 272560011643 3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314 272560011644 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 272560011645 dimer interface [polypeptide binding]; other site 272560011646 active site 272560011647 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 229.7, E-value 2.7e-66 272560011648 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 290.9, E-value 1.1e-84 272560011649 PS00606 Beta-ketoacyl synthases active site. 272560011650 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011651 acyl carrier protein; Provisional; Region: acpP; PRK00982 272560011652 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 85.7, E-value 5.9e-23 272560011653 PS00012 Phosphopantetheine attachment site. 272560011654 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 272560011655 3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830 272560011656 NAD(P) binding site [chemical binding]; other site 272560011657 homotetramer interface [polypeptide binding]; other site 272560011658 homodimer interface [polypeptide binding]; other site 272560011659 active site 272560011660 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 319.9, E-value 1.9e-93 272560011661 PS00061 Short-chain dehydrogenases/reductases family signature. 272560011662 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331 272560011663 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 212.5, E-value 4e-61 272560011664 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 272560011665 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 272560011666 dimer interface [polypeptide binding]; other site 272560011667 active site 272560011668 CoA binding pocket [chemical binding]; other site 272560011669 putative phosphate acyltransferase; Provisional; Region: PRK05331 272560011670 Pfam match to entry PF02504 FA_synthesis, Fatty acid synthesis protein , score 474.0, E-value 7.9e-140 272560011671 PS00196 Type-1 copper (blue) proteins signature. 272560011672 50S ribosomal protein L32; Validated; Region: rpmF; PRK01110 272560011673 Uncharacterized ACR, COG1399; Region: DUF177; pfam02620 272560011674 Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555 272560011675 active site 272560011676 dimer interface [polypeptide binding]; other site 272560011677 Pfam match to entry PF02545 Maf, Maf-like protein , score 180.7, E-value 1.5e-51 272560011678 Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649 272560011679 putative SAM binding site [chemical binding]; other site 272560011680 homodimer interface [polypeptide binding]; other site 272560011681 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score -3.7, E-value 1.3e-05 272560011682 Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616 272560011683 Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023 272560011684 tandem repeat interface [polypeptide binding]; other site 272560011685 oligomer interface [polypeptide binding]; other site 272560011686 active site residues [active] 272560011687 Pfam match to entry PF01343 Peptidase_U7, Peptidase U7 , score 145.6, E-value 5.9e-41 272560011688 1 probable transmembrane helix predicted for BPSL2448 by TMHMM2.0 at aa 21-43 272560011689 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cd03467 272560011690 iron-sulfur cluster [ion binding]; other site 272560011691 [2Fe-2S] cluster binding site [ion binding]; other site 272560011692 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 30.5, E-value 4.4e-07 272560011693 Predicted phosphatases [General function prediction only]; Region: Gph; COG0546 272560011694 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560011695 active site 272560011696 motif I; other site 272560011697 motif II; other site 272560011698 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 118.5, E-value 8e-33 272560011699 23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025 272560011700 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560011701 RNA binding surface [nucleotide binding]; other site 272560011702 Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869 272560011703 active site 272560011704 Pfam match to entry PF00849 PseudoU_synth_2, RNA pseudouridylate synthase , score 149.9, E-value 2.8e-42 272560011705 PS01129 Rlu family of pseudouridine synthase signature. 272560011706 Pfam match to entry PF01479 S4, S4 domain , score 35.5, E-value 8e-08 272560011707 Ribonucleases G and E [Translation, ribosomal structure and biogenesis]; Region: CafA; COG1530 272560011708 S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453 272560011709 homodimer interface [polypeptide binding]; other site 272560011710 oligonucleotide binding site [chemical binding]; other site 272560011711 Ribonuclease E/G family; Region: RNase_E_G; pfam10150 272560011712 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 56.1, E-value 5e-14 272560011713 molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164 272560011714 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560011715 FeS/SAM binding site; other site 272560011716 Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463 272560011717 PS01305 moaA / nifB / pqqE family signature. 272560011718 Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / nifB / pqqE family , score 178.0, E-value 1e-50 272560011719 MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503 272560011720 GTP binding site; other site 272560011721 Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303 272560011722 MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887 272560011723 dimer interface [polypeptide binding]; other site 272560011724 putative functional site; other site 272560011725 putative MPT binding site; other site 272560011726 Pfam match to entry PF03453 MoeA_N, MoeA N-terminal region (domain I and II) , score 205.4, E-value 5.8e-59 272560011727 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain , score 173.4, E-value 2.4e-49 272560011728 Pfam match to entry PF03454 MoeA_C, MoeA C-terminal region (domain IV) , score 70.1, E-value 3.1e-18 272560011729 2 probable transmembrane helices predicted for BPSL2456 by TMHMM2.0 at aa 16-38 and 48-70 272560011730 Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673 272560011731 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560011732 Coenzyme A binding pocket [chemical binding]; other site 272560011733 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 83.2, E-value 3.4e-22 272560011734 Signal peptide predicted for BPSL2458 by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.682 between residues 20 and 21; signal peptide 272560011735 RmuC family; Region: RmuC; pfam02646 272560011736 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 272560011737 D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301 272560011738 dimerization interface [polypeptide binding]; other site 272560011739 ligand binding site [chemical binding]; other site 272560011740 NADP binding site [chemical binding]; other site 272560011741 catalytic site [active] 272560011742 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 185.8, E-value 4.5e-53 272560011743 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560011744 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 77.8, E-value 1.4e-20 272560011745 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 272560011746 transmembrane helices; other site 272560011747 12 probable transmembrane helices predicted for BPSL2460 by TMHMM2.0 at aa 4-26, 33-55, 70-92, 99-116, 131-153, 166-188, 203-225, 260-282, 329-351, 372-394, 409-431 and 451-473 272560011748 Uncharacterized conserved protein [Function unknown]; Region: COG1556 272560011749 Pfam match to entry PF02589 DUF162, Uncharacterized ACR, YkgG family COG1556 , score 37.7, E-value 1.7e-08 272560011750 PS00191 Cytochrome b5 family, heme-binding domain signature. 272560011751 nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514 272560011752 Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401 272560011753 active site 272560011754 PS00213 Lipocalin signature. 272560011755 Ferredoxin [Energy production and conversion]; Region: COG1146 272560011756 4Fe-4S binding domain; Region: Fer4; pfam00037 272560011757 Domain of unknown function (DUF3470); Region: DUF3470; pfam11953 272560011758 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 13.0, E-value 0.0016 272560011759 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 32.9, E-value 4.9e-07 272560011760 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560011761 Signal peptide predicted for BPSL2464 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.881 between residues 24 and 25; signal peptide 272560011762 CreA protein; Region: CreA; pfam05981 272560011763 Protein of unknown function (DUF4088); Region: DUF4088; pfam13317 272560011764 Signal peptide predicted for BPSL2466 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 28 and 29; signal peptide 272560011765 Pfam match to entry PF02987 LEA, Late embryogenesis abundant protein , score 1.4, E-value 0.12 272560011766 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560011767 RNA binding surface [nucleotide binding]; other site 272560011768 multidrug efflux protein; Reviewed; Region: PRK01766 272560011769 Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131 272560011770 cation binding site [ion binding]; other site 272560011771 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 76.2, E-value 4.5e-20 272560011772 11 probable transmembrane helices predicted for BPSL2468 by TMHMM2.0 at aa 62-84, 105-127, 147-169, 178-200, 210-232, 253-275, 285-307, 328-350, 365-387, 406-428 and 438-457 272560011773 Pfam match to entry PF01554 UPF0013, Uncharacterized membrane protein family UPF0013 , score 134.7, E-value 1.1e-37 272560011774 PS00012 Phosphopantetheine attachment site. 272560011775 fumarate hydratase; Reviewed; Region: fumC; PRK00485 272560011776 Class II fumarases; Region: Fumarase_classII; cd01362 272560011777 active site 272560011778 tetramer interface [polypeptide binding]; other site 272560011779 Pfam match to entry PF00206 lyase_1, Lyase , score 741.3, E-value 2.8e-220 272560011780 PS00163 Fumarate lyases signature. 272560011781 Brown fat-inducible thioesterase (BFIT). Brain acyl-CoA hydrolase (BACH). These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442 272560011782 Pfam match to entry PF01662 Acyl-CoA_hydro, Cytosolic long-chain acyl-CoA thioester hydrolase , score 152.7, E-value 4.1e-43 272560011783 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560011784 dimerization interface [polypeptide binding]; other site 272560011785 putative DNA binding site [nucleotide binding]; other site 272560011786 putative Zn2+ binding site [ion binding]; other site 272560011787 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 52.4, E-value 6.3e-13 272560011788 Predicted helix-turn-helix motif with score 1041.000, SD 2.73 at aa 44-65, sequence RPAGELTMIAGLSPSAASAHLA 272560011789 Signal peptide predicted for BPSL2472 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.916 between residues 34 and 35; signal peptide 272560011790 FecR protein; Region: FecR; pfam04773 272560011791 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 272560011792 dimerization interface [polypeptide binding]; other site 272560011793 active site 272560011794 Pfam match to entry PF00303 thymidylat_synt, Thymidylate synthase , score 321.5, E-value 6.4e-94 272560011795 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560011796 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560011797 Walker A motif; other site 272560011798 ATP binding site [chemical binding]; other site 272560011799 Walker B motif; other site 272560011800 arginine finger; other site 272560011801 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560011802 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 43.5, E-value 3.1e-10 272560011803 Predicted helix-turn-helix motif with score 2260.000, SD 6.88 at aa 418-439, sequence GRLADAARELGVSRVTLYRLLC 272560011804 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560011805 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 406.2, E-value 2e-119 272560011806 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560011807 Signal peptide predicted for BPSL2472 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.906 between residues 31 and 32; signal peptide 272560011808 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560011809 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560011810 Walker A motif; other site 272560011811 ATP binding site [chemical binding]; other site 272560011812 Walker B motif; other site 272560011813 arginine finger; other site 272560011814 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 272560011815 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 408.8, E-value 3.4e-120 272560011816 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560011817 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560011818 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 32.4, E-value 6.8e-07 272560011819 Predicted helix-turn-helix motif with score 1646.000, SD 4.79 at aa 439-460, sequence NRLTEAAAELGVSRATLYRLMV 272560011820 Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209 272560011821 folate binding site [chemical binding]; other site 272560011822 NADP+ binding site [chemical binding]; other site 272560011823 Pfam match to entry PF00186 DiHfolate_red, Dihydrofolate reductase , score 201.0, E-value 1.2e-57 272560011824 PS00075 Dihydrofolate reductase signature. 272560011825 Transposase domain (DUF772); Region: DUF772; pfam05598 272560011826 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560011827 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score -1.8, E-value 0.0062 272560011828 Putative modulator of DNA gyrase; Region: PmbA_TldD; cl19356 272560011829 Pfam match to entry PF01523 PmbA_TldD, modulator of DNA gyrase , score 184.9, E-value 8.2e-53 272560011830 hypothetical protein; Provisional; Region: PRK05255 272560011831 MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886 272560011832 MPT binding site; other site 272560011833 trimer interface [polypeptide binding]; other site 272560011834 Pfam match to entry PF00994 MoCF_biosynth, Probable molybdopterin binding domain , score 124.6, E-value 1.2e-34 272560011835 PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 272560011836 DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135 272560011837 catalytic site [active] 272560011838 putative active site [active] 272560011839 putative substrate binding site [chemical binding]; other site 272560011840 dimer interface [polypeptide binding]; other site 272560011841 Pfam match to entry PF00929 Exonuclease, Exonuclease , score 129.5, E-value 4e-36 272560011842 Peptidase family M48; Region: Peptidase_M48; cl12018 272560011843 7 probable transmembrane helices predicted for BPSL2482 by TMHMM2.0 at aa 4-26, 67-89, 104-126, 148-170, 174-196, 294-316 and 331-353 272560011844 Pfam match to entry PF01435 Peptidase_M48, Peptidase M48 , score 200.1, E-value 2.2e-57 272560011845 GTPase RsgA; Reviewed; Region: PRK00098 272560011846 S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466 272560011847 RNA binding site [nucleotide binding]; other site 272560011848 homodimer interface [polypeptide binding]; other site 272560011849 Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854 272560011850 GTPase/Zn-binding domain interface [polypeptide binding]; other site 272560011851 GTP/Mg2+ binding site [chemical binding]; other site 272560011852 G4 box; other site 272560011853 G5 box; other site 272560011854 G1 box; other site 272560011855 Switch I region; other site 272560011856 G2 box; other site 272560011857 G3 box; other site 272560011858 Switch II region; other site 272560011859 Pfam match to entry PF03193 DUF258, Protein of unknown function, DUF258 , score 171.1, E-value 1.2e-48 272560011860 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011861 Domain of unknown function (DUF2007); Region: DUF2007; pfam09413 272560011862 CobD/CbiB family protein; Provisional; Region: PRK07630 272560011863 5 probable transmembrane helices predicted for BPSL2485 by TMHMM2.0 at aa 13-35, 65-87, 89-111, 166-188 and 306-328 272560011864 Pfam match to entry PF03186 CobD_Cbib, CobD/Cbib protein , score -92.6, E-value 8.8e-07 272560011865 Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426 272560011866 putative active site [active] 272560011867 putative CoA binding site [chemical binding]; other site 272560011868 nudix motif; other site 272560011869 metal binding site [ion binding]; metal-binding site 272560011870 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 36.4, E-value 4.3e-08 272560011871 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560011872 Coenzyme A binding pocket [chemical binding]; other site 272560011873 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 33.5, E-value 3.2e-07 272560011874 PF1610 272560011875 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560011876 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560011877 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560011878 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560011879 Pfam match to entry PF01610 Transposase_12, Transposase , score 371.8, E-value 4.5e-109 272560011880 50S ribosomal protein L19; Provisional; Region: rplS; PRK05338 272560011881 Pfam match to entry PF01245 Ribosomal_L19, Ribosomal protein L19 , score 215.6, E-value 4.9e-62 272560011882 PS01015 Ribosomal protein L19 signature. 272560011883 tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026 272560011884 Pfam match to entry PF01746 tRNA_m1G_MT, tRNA (Guanine-1)-methyltransferase , score 364.2, E-value 8.8e-107 272560011885 16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122 272560011886 RimM N-terminal domain; Region: RimM; pfam01782 272560011887 PRC-barrel domain; Region: PRC; pfam05239 272560011888 Pfam match to entry PF01782 RimM, RimM , score 72.9, E-value 4.3e-19 272560011889 30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040 272560011890 Pfam match to entry PF00886 Ribosomal_S16, Ribosomal protein S16 , score 103.8, E-value 2.1e-28 272560011891 Signal peptide predicted for BPSL2493 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.780 between residues 26 and 27; signal peptide 272560011892 Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133 272560011893 dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; cl19645 272560011894 TM2 domain; Region: TM2; pfam05154 272560011895 Domain of unknown function (DUF373); Region: DUF373; cl12079 272560011896 4 probable transmembrane helices predicted for BPSL2494 by TMHMM2.0 at aa 15-34, 41-60, 70-92 and 113-135 272560011897 DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533 272560011898 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560011899 FeS/SAM binding site; other site 272560011900 Pfam match to entry PF01932 DUF85, Domain of unknown function DUF85 , score 159.1, E-value 5e-45 272560011901 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 272560011902 leucine-responsive transcriptional regulator; Provisional; Region: PRK11169 272560011903 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560011904 putative DNA binding site [nucleotide binding]; other site 272560011905 putative Zn2+ binding site [ion binding]; other site 272560011906 AsnC family; Region: AsnC_trans_reg; pfam01037 272560011907 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 173.9, E-value 1.7e-49 272560011908 PS00519 Bacterial regulatory proteins, asnC family signature. 272560011909 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 272560011910 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560011911 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560011912 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -82.8, E-value 0.0014 272560011913 acyl-CoA dehydrogenase; Provisional; Region: PTZ00456 272560011914 Acyl-CoA dehydrogenase N terminal; Region: AcylCoA_DH_N; pfam12418 272560011915 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560011916 active site 272560011917 Acetyl-CoA dehydrogenase C-terminal like; Region: Acyl-CoA_dh_C; pfam12806 272560011918 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 194.3, E-value 1.3e-55 272560011919 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 27.5, E-value 6.9e-09 272560011920 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715 272560011921 electron transfer flavoprotein subunit alpha; Provisional; Region: PLN00022 272560011922 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 272560011923 PS00696 Electron transfer flavoprotein alpha-subunit signature. 272560011924 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit , score 408.5, E-value 4e-120 272560011925 The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714 272560011926 Ligand binding site [chemical binding]; other site 272560011927 Pfam match to entry PF01012 ETF_beta, Electron transfer flavoprotein beta subunit , score 389.3, E-value 2.5e-114 272560011928 PS01065 Electron transfer flavoprotein beta-subunit signature. 272560011929 Signal peptide predicted for BPSL2501 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.986 between residues 38 and 39; signal peptide 272560011930 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 272560011931 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein , score 453.2, E-value 1.4e-133 272560011932 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560011933 dimer interface [polypeptide binding]; other site 272560011934 conserved gate region; other site 272560011935 putative PBP binding loops; other site 272560011936 ABC-ATPase subunit interface; other site 272560011937 5 probable transmembrane helices predicted for BPSL2502 by TMHMM2.0 at aa 18-40, 60-82, 86-108, 146-168 and 188-210 272560011938 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 77.5, E-value 1.8e-20 272560011939 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560011940 DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153 272560011941 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 272560011942 Walker A/P-loop; other site 272560011943 ATP binding site [chemical binding]; other site 272560011944 Q-loop/lid; other site 272560011945 ABC transporter signature motif; other site 272560011946 Walker B; other site 272560011947 D-loop; other site 272560011948 H-loop/switch region; other site 272560011949 This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930 272560011950 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 235.4, E-value 5.4e-68 272560011951 PS00211 ABC transporters family signature. 272560011952 PS00017 ATP/GTP-binding site motif A (P-loop). 272560011953 Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267 272560011954 Putative lysophospholipase; Region: Hydrolase_4; pfam12146 272560011955 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 46.0, E-value 5.3e-11 272560011956 PS00120 Lipases, serine active site. 272560011957 Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII_2; cd11599 272560011958 putative active site [active] 272560011959 Zn binding site [ion binding]; other site 272560011960 Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase , score 316.9, E-value 1.5e-92 272560011961 Signal peptide predicted for BPSL2506 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.979 between residues 53 and 54; signal peptide 272560011962 Transglycosylase SLT domain; Region: SLT_2; cl19381 272560011963 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560011964 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560011965 catalytic residue [active] 272560011966 cysteine synthase; Region: PLN02565 272560011967 CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561 272560011968 dimer interface [polypeptide binding]; other site 272560011969 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560011970 catalytic residue [active] 272560011971 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 339.2, E-value 3e-99 272560011972 PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 272560011973 Signal peptide predicted for BPSL2508 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.759 between residues 20 and 21; signal peptide 272560011974 Helix-hairpin-helix motif; Region: HHH_3; pfam12836 272560011975 ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248 272560011976 ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197 272560011977 NADP binding site [chemical binding]; other site 272560011978 homopentamer interface [polypeptide binding]; other site 272560011979 substrate binding site [chemical binding]; other site 272560011980 active site 272560011981 ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870 272560011982 RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172 272560011983 putative ribose interaction site [chemical binding]; other site 272560011984 putative ADP binding site [chemical binding]; other site 272560011985 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 154.0, E-value 1.7e-43 272560011986 PS00583 pfkB family of carbohydrate kinases signature 1. 272560011987 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 272560011988 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721 272560011989 Signal peptide predicted for BPSL2511 by SignalP 2.0 HMM (Signal peptide probabilty 0.760) with cleavage site probability 0.751 between residues 20 and 21; signal peptide 272560011990 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 272560011991 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 272560011992 Pfam match to entry PF03720 UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain , score 123.6, E-value 2.4e-34 272560011993 Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase, central domain , score 180.7, E-value 1.5e-51 272560011994 Pfam match to entry PF03721 UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain , score 300.5, E-value 1.3e-87 272560011995 tetratricopeptide repeat protein; Provisional; Region: PRK11788 272560011996 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560011997 binding surface 272560011998 TPR motif; other site 272560011999 Pfam match to entry PF00515 TPR, TPR Domain , score 8.6, E-value 0.35 272560012000 Pfam match to entry PF00515 TPR, TPR Domain , score 12.6, E-value 0.13 272560012001 Pfam match to entry PF00515 TPR, TPR Domain , score 7.5, E-value 0.46 272560012002 Pfam match to entry PF00515 TPR, TPR Domain , score 9.6, E-value 0.27 272560012003 1 probable transmembrane helix predicted for BPSL2512 by TMHMM2.0 at aa 5-22 272560012004 Protein of unknown function (DUF1049); Region: DUF1049; pfam06305 272560012005 2 probable transmembrane helices predicted for BPSL2513 by TMHMM2.0 at aa 79-101 and 116-138 272560012006 Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836 272560012007 dimer interface [polypeptide binding]; other site 272560012008 DNA binding site [nucleotide binding] 272560012009 Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein , score 153.9, E-value 1.8e-43 272560012010 30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299 272560012011 S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687 272560012012 RNA binding site [nucleotide binding]; other site 272560012013 S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465 272560012014 RNA binding site [nucleotide binding]; other site 272560012015 S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688 272560012016 RNA binding site [nucleotide binding]; other site 272560012017 S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689 272560012018 RNA binding site [nucleotide binding]; other site 272560012019 S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927 272560012020 RNA binding site [nucleotide binding]; other site 272560012021 S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691 272560012022 RNA binding site [nucleotide binding]; other site 272560012023 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 73.6, E-value 2.7e-19 272560012024 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 81.6, E-value 1e-21 272560012025 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 100.1, E-value 2.8e-27 272560012026 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 115.3, E-value 7.4e-32 272560012027 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 63.8, E-value 2.5e-16 272560012028 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 36.6, E-value 3.8e-08 272560012029 cytidylate kinase; Provisional; Region: cmk; PRK00023 272560012030 Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020 272560012031 CMP-binding site; other site 272560012032 The sites determining sugar specificity; other site 272560012033 Pfam match to entry PF02224 Cytidylate_kin, Cytidylate kinase , score 224.5, E-value 1e-64 272560012034 bifunctional prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK11861 272560012035 prephenate dehydrogenase; Validated; Region: PRK08507 272560012036 EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556 272560012037 hinge; other site 272560012038 active site 272560012039 Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) , score 585.0, E-value 3e-173 272560012040 PS00885 EPSP synthase signature 2. 272560012041 PS00104 EPSP synthase signature 1. 272560012042 Pfam match to entry PF02153 PDH, Prephenate dehydrogenase , score 274.7, E-value 7.8e-80 272560012043 1 probable transmembrane helix predicted for BPSL2517 by TMHMM2.0 at aa 7-29 272560012044 Chorismate mutase type II; Region: CM_2; smart00830 272560012045 Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077 272560012046 Prephenate dehydratase; Region: PDT; pfam00800 272560012047 C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905 272560012048 putative L-Phe binding site [chemical binding]; other site 272560012049 Pfam match to entry PF01842 ACT, ACT domain , score 51.8, E-value 9.5e-13 272560012050 Pfam match to entry PF00800 PDT, Prephenate dehydratase , score 262.6, E-value 3.4e-76 272560012051 Pfam match to entry PF01817 Chorismate_mut, Chorismate mutase , score 52.2, E-value 7.2e-13 272560012052 Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT). PSAT is active as...; Region: PSAT_like; cd00611 272560012053 homodimer interface [polypeptide binding]; other site 272560012054 substrate-cofactor binding pocket; other site 272560012055 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560012056 catalytic residue [active] 272560012057 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 246.4, E-value 2.5e-71 272560012058 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 272560012059 Signal peptide predicted for BPSL2520 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.684 between residues 34 and 35; signal peptide 272560012060 Uncharacterized protein conserved in bacteria (DUF2059); Region: DUF2059; pfam09832 272560012061 DNA gyrase subunit A; Validated; Region: PRK05560 272560012062 DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187 272560012063 CAP-like domain; other site 272560012064 active site 272560012065 primary dimer interface [polypeptide binding]; other site 272560012066 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012067 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012068 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012069 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012070 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012071 DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989 272560012072 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 60.2, E-value 3e-15 272560012073 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 60.8, E-value 2e-15 272560012074 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 49.8, E-value 3.8e-12 272560012075 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 42.0, E-value 9e-10 272560012076 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 55.7, E-value 6.4e-14 272560012077 Pfam match to entry PF03989 DNA_gyraseA_C, DNA gyrase C-terminal domain, beta-propeller , score 57.5, E-value 1.8e-14 272560012078 Pfam match to entry PF00521 DNA_topoisoIV, DNA gyrase/topoisomerase IV, subunit A , score 1037.2, E-value 0 272560012079 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560012080 ligand binding site [chemical binding]; other site 272560012081 Pfam match to entry PF00691 OmpA, OmpA family , score 135.4, E-value 6.6e-38 272560012082 Signal peptide predicted for BPSL2523 by SignalP 2.0 HMM (Signal peptide probabilty 0.719) with cleavage site probability 0.299 between residues 18 and 19 272560012083 bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134 272560012084 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560012085 S-adenosylmethionine binding site [chemical binding]; other site 272560012086 phosphoglycolate phosphatase; Provisional; Region: PRK13222 272560012087 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560012088 trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187; cl17105 272560012089 active site 272560012090 motif I; other site 272560012091 motif II; other site 272560012092 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 124.3, E-value 1.5e-34 272560012093 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560012094 S-adenosylmethionine binding site [chemical binding]; other site 272560012095 Signal peptide predicted for BPSL2526 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.988 between residues 26 and 27; signal peptide 272560012096 PS00294 Prenyl group binding site (CAAX box). 272560012097 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549 272560012098 aminoethylphosphonate catabolism associated LysR family transcriptional regulator; Region: phn_lysR; TIGR03339 272560012099 PBP superfamily domain; Region: PBP_like; pfam12727 272560012100 Pfam match to entry PF02573 HTH_9, N-terminal HTH domain of molybdenum-binding protein , score 38.3, E-value 1.2e-08 272560012101 Predicted helix-turn-helix motif with score 1002.000, SD 2.60 at aa 36-57, sequence GSIAQAAHAKGLSYRHAWGLLR 272560012102 Thioredoxin-like [2Fe-2S] ferredoxin; Region: 2Fe-2S_thioredx; pfam01257 272560012103 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily, NAD-dependent formate dehydrogenase (FDH) gamma subunit; composed of proteins similar to the gamma subunit of NAD-linked FDH of Ralstonia eutropha, a...; Region: TRX_Fd_NuoE_FDH_gamma; cd03081 272560012104 putative dimer interface [polypeptide binding]; other site 272560012105 [2Fe-2S] cluster binding site [ion binding]; other site 272560012106 TRX-like [2Fe-2S] Ferredoxin (Fd) family, NAD-dependent formate dehydrogenase (FDH) beta subunit; composed of proteins similar to the beta subunit of NAD-linked FDH of Ralstonia eutropha, a soluble enzyme that catalyzes the irreversible oxidation of...; Region: TRX_Fd_FDH_beta; cd03063 272560012107 putative dimer interface [polypeptide binding]; other site 272560012108 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894 272560012109 Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512 272560012110 SLBB domain; Region: SLBB; pfam10531 272560012111 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928 272560012112 Pfam match to entry PF01512 Complex1_51K, Respiratory-chain NADH dehydrogenase 51 Kd subunit , score 356.7, E-value 1.6e-104 272560012113 PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 272560012114 PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 272560012115 Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383 272560012116 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560012117 catalytic loop [active] 272560012118 iron binding site [ion binding]; other site 272560012119 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; smart00929 272560012120 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560012121 Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753 272560012122 [4Fe-4S] binding site [ion binding]; other site 272560012123 molybdopterin cofactor binding site; other site 272560012124 This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508 272560012125 molybdopterin cofactor binding site; other site 272560012126 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 39.4, E-value 5.3e-09 272560012127 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 10.6, E-value 0.0038 272560012128 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560012129 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 23.6, E-value 3.5e-05 272560012130 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560012131 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 472.7, E-value 1.9e-139 272560012132 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560012133 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 110.2, E-value 2.6e-30 272560012134 PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 272560012135 NADH-dependant formate dehydrogenase delta subunit FdsD; Region: FdsD; pfam11390 272560012136 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560012137 hypothetical protein; Provisional; Region: PRK06184 272560012138 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 161.5, E-value 9.5e-46 272560012139 Pfam match to entry PF01494 FAD_binding_3, FAD binding domain , score 75.1, E-value 9.7e-20 272560012140 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560012141 binding surface 272560012142 Tetratricopeptide repeat; Region: TPR_16; pfam13432 272560012143 TPR motif; other site 272560012144 TPR repeat; Region: TPR_11; pfam13414 272560012145 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560012146 binding surface 272560012147 TPR motif; other site 272560012148 TPR repeat; Region: TPR_11; pfam13414 272560012149 TPR repeat; Region: TPR_11; pfam13414 272560012150 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560012151 binding surface 272560012152 TPR motif; other site 272560012153 TPR repeat; Region: TPR_11; pfam13414 272560012154 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560012155 binding surface 272560012156 TPR motif; other site 272560012157 TPR repeat; Region: TPR_11; pfam13414 272560012158 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560012159 Pfam match to entry PF00515 TPR, TPR Domain , score 6.6, E-value 0.58 272560012160 Pfam match to entry PF00515 TPR, TPR Domain , score 16.6, E-value 0.038 272560012161 Pfam match to entry PF00515 TPR, TPR Domain , score 29.4, E-value 5.4e-06 272560012162 Pfam match to entry PF00515 TPR, TPR Domain , score 42.9, E-value 4.8e-10 272560012163 Pfam match to entry PF00515 TPR, TPR Domain , score 47.5, E-value 2e-11 272560012164 Pfam match to entry PF00515 TPR, TPR Domain , score 35.6, E-value 7.3e-08 272560012165 citrate-proton symporter; Provisional; Region: PRK15075 272560012166 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560012167 putative substrate translocation pore; other site 272560012168 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 241.5, E-value 7.5e-70 272560012169 12 probable transmembrane helices predicted for BPSL2534 by TMHMM2.0 at aa 39-61, 76-98, 107-129, 139-161, 182-199, 209-226, 258-280, 295-317, 324-346, 356-375, 388-410 and 420-438 272560012170 PS00216 Sugar transport proteins signature 1. 272560012171 PS00217 Sugar transport proteins signature 2. 272560012172 Signal peptide predicted for BPSL2535 by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.497 between residues 27 and 28; signal peptide 272560012173 Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071 272560012174 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 272560012175 catalytic triad [active] 272560012176 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score -20.5, E-value 4.6e-06 272560012177 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012178 amidase; Provisional; Region: PRK07056 272560012179 Pfam match to entry PF01425 Amidase, Amidase , score 336.6, E-value 1.8e-98 272560012180 PS00571 Amidases signature. 272560012181 Signal peptide predicted for BPSL2537 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.410 between residues 29 and 30; signal peptide 272560012182 disulfide bond formation protein B; Provisional; Region: PRK02110 272560012183 Pfam match to entry PF02600 DsbB, Disulfide bond formation protein DsbB , score 61.5, E-value 1.2e-15 272560012184 4 probable transmembrane helices predicted for BPSL2537 by TMHMM2.0 at aa 13-35, 50-72, 77-94 and 140-162 272560012185 XdhC and CoxI family; Region: XdhC_CoxI; pfam02625 272560012186 xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964 272560012187 XdhC Rossmann domain; Region: XdhC_C; pfam13478 272560012188 Pfam match to entry PF02625 DUF182, Uncharacterized BCR, COG1975 , score -42.5, E-value 1.1e-05 272560012189 Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320 272560012190 active site 272560012191 purine riboside binding site [chemical binding]; other site 272560012192 Pfam match to entry PF00962 A_deaminase, Adenosine/AMP deaminase , score 264.9, E-value 6.8e-77 272560012193 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 272560012194 Pfam match to entry PF00860 xan_ur_permease, Permease , score 70.6, E-value 2.2e-18 272560012195 12 probable transmembrane helices predicted for BPSL2540 by TMHMM2.0 at aa 45-67, 72-94, 99-116, 121-143, 156-175, 190-212, 219-238, 281-303, 323-345, 355-374, 376-398 and 418-440 272560012196 guanine deaminase; Provisional; Region: PRK09228 272560012197 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560012198 active site 272560012199 Pfam match to entry PF01685 ATZ_TRZ, Chlorohydrolase , score 211.6, E-value 7.8e-61 272560012200 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560012201 Predicted membrane protein [Function unknown]; Region: COG2119 272560012202 Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169 272560012203 Uncharacterized protein family UPF0016; Region: UPF0016; pfam01169 272560012204 5 probable transmembrane helices predicted for BPSL2542 by TMHMM2.0 at aa 35-57, 67-86, 98-115, 135-157 and 164-186 272560012205 Pfam match to entry PF01169 UPF0016, Uncharacterized protein family UPF0016 , score 57.2, E-value 2.3e-14 272560012206 Domain of unknown function (DUF4136); Region: DUF4136; pfam13590 272560012207 aminopeptidase N; Provisional; Region: pepN; PRK14015 272560012208 Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600 272560012209 active site 272560012210 Zn binding site [ion binding]; other site 272560012211 Pfam match to entry PF01433 Peptidase_M1, Peptidase M1 , score 198.7, E-value 6.1e-57 272560012212 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560012213 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222 272560012214 CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312 272560012215 THF binding site; other site 272560012216 CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311 272560012217 substrate binding site [chemical binding]; other site 272560012218 THF binding site; other site 272560012219 zinc-binding site [ion binding]; other site 272560012220 Pfam match to entry PF01717 Methionine_synt, Methionine synthase, vitamin-B12 independent , score 653.7, E-value 6.2e-194 272560012221 DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421 272560012222 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560012223 The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441 272560012224 putative dimerization interface [polypeptide binding]; other site 272560012225 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 97.2, E-value 2.1e-26 272560012226 Predicted helix-turn-helix motif with score 1799.000, SD 5.31 at aa 21-42, sequence GNLSRAAQVLCLTQSALSHQLK 272560012227 PS00044 Bacterial regulatory proteins, lysR family signature. 272560012228 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 140.7, E-value 1.7e-39 272560012229 Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354 272560012230 AMP binding site [chemical binding]; other site 272560012231 metal binding site [ion binding]; metal-binding site 272560012232 active site 272560012233 Pfam match to entry PF00316 FBPase, Fructose-1-6-bisphosphatase , score 583.0, E-value 1.2e-172 272560012234 Predicted membrane protein [Function unknown]; Region: COG2261 272560012235 3 probable transmembrane helices predicted for BPSL2550 by TMHMM2.0 at aa 31-53, 60-82 and 87-109 272560012236 Signal peptide predicted for BPSL2551 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.609 between residues 22 and 23; signal peptide 272560012237 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 272560012238 catalytic residues [active] 272560012239 Signal peptide predicted for BPSL2552 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.838 between residues 22 and 23; signal peptide 272560012240 BNR repeat-like domain; Region: BNR_2; pfam13088 272560012241 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 13.4, E-value 0.36 272560012242 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 13.1, E-value 0.44 272560012243 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 12.5, E-value 0.65 272560012244 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 1.0, E-value 20 272560012245 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012246 Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629 272560012247 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560012248 N-terminal plug; other site 272560012249 ligand-binding site [chemical binding]; other site 272560012250 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 61.5, E-value 1.2e-15 272560012251 Protein of unknown function (DUF2946); Region: DUF2946; pfam11162 272560012252 1 probable transmembrane helix predicted for BPSL2554 by TMHMM2.0 at aa 38-60 272560012253 chorismate mutase; Provisional; Region: PRK09269 272560012254 Signal peptide predicted for BPSL2555 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.507 between residues 25 and 26; signal peptide 272560012255 Chorismate mutase type II; Region: CM_2; cl00693 272560012256 Pfam match to entry PF01817 Chorismate_mut, Chorismate mutase , score 34.0, E-value 2.3e-07 272560012257 exonuclease, DNA polymerase III, epsilon subunit family; Region: dnaq; TIGR00573 272560012258 DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127 272560012259 active site 272560012260 catalytic site [active] 272560012261 substrate binding site [chemical binding]; other site 272560012262 Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434 272560012263 GIY-YIG motif/motif A; other site 272560012264 active site 272560012265 catalytic site [active] 272560012266 putative DNA binding site [nucleotide binding]; other site 272560012267 metal binding site [ion binding]; metal-binding site 272560012268 Pfam match to entry PF00929 Exonuclease, Exonuclease , score 129.7, E-value 3.5e-36 272560012269 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 272560012270 DNA-binding site [nucleotide binding]; DNA binding site 272560012271 RNA-binding motif; other site 272560012272 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain , score 137.5, E-value 1.6e-38 272560012273 PS00352 'Cold-shock' DNA-binding domain signature. 272560012274 Signal peptide predicted for BPSL2559 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 20 and 21; signal peptide 272560012275 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560012276 trimer interface [polypeptide binding]; other site 272560012277 eyelet of channel; other site 272560012278 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -55.3, E-value 0.00044 272560012279 transcription elongation factor GreB; Reviewed; Region: greB; PRK01885 272560012280 Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449 272560012281 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 272560012282 Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain , score 69.0, E-value 6.6e-18 272560012283 PS00830 Prokaryotic transcription elongation factors signature 2. 272560012284 Pfam match to entry PF03449 GreA_GreB_N, Prokaryotic transcription elongation factor, GreA/GreB, N-terminal domain , score 121.5, E-value 1e-33 272560012285 PS00829 Prokaryotic transcription elongation factors signature 1. 272560012286 Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317 272560012287 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560012288 Zn2+ binding site [ion binding]; other site 272560012289 Mg2+ binding site [ion binding]; other site 272560012290 Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399 272560012291 synthetase active site [active] 272560012292 NTP binding site [chemical binding]; other site 272560012293 metal binding site [ion binding]; metal-binding site 272560012294 TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668 272560012295 ACT domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876 272560012296 Pfam match to entry PF01842 ACT, ACT domain , score 21.5, E-value 0.0013 272560012297 Pfam match to entry PF02824 TGS, TGS domain , score 92.6, E-value 5.1e-25 272560012298 Pfam match to entry PF01966 HD, HD domain , score 55.6, E-value 6.9e-14 272560012299 DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392 272560012300 Pfam match to entry PF01192 RNA_pol_Rpb6, RNA polymerase Rpb6 , score 55.0, E-value 1.1e-13 272560012301 Guanylate kinase; Region: Guanylate_kin; pfam00625 272560012302 Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071 272560012303 catalytic site [active] 272560012304 G-X2-G-X-G-K; other site 272560012305 Pfam match to entry PF00625 Guanylate_kin, Guanylate kinase , score 129.0, E-value 5.8e-36 272560012306 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012307 hypothetical protein; Provisional; Region: PRK11820 272560012308 YicC-like family, N-terminal region; Region: YicC_N; pfam03755 272560012309 Domain of unknown function (DUF1732); Region: DUF1732; pfam08340 272560012310 Pfam match to entry PF03755 YicC_N-term, YicC-like family, N-terminal region , score 131.4, E-value 1.1e-36 272560012311 ribonuclease PH; Reviewed; Region: rph; PRK00173 272560012312 Ribonuclease PH; Region: RNase_PH_bact; cd11362 272560012313 hexamer interface [polypeptide binding]; other site 272560012314 active site 272560012315 Pfam match to entry PF01138 RNase_PH, 3' exoribonuclease, domain 1 , score 174.9, E-value 8.9e-50 272560012316 PS01277 Ribonuclease PH signature. 272560012317 Pfam match to entry PF03725 RNase_PH_C, 3' exoribonuclease, domain 2 , score 81.3, E-value 1.3e-21 272560012318 NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515 272560012319 active site 272560012320 dimerization interface [polypeptide binding]; other site 272560012321 Pfam match to entry PF01725 Ham1p_like, Ham1 family , score 237.4, E-value 1.3e-68 272560012322 coproporphyrinogen III oxidase; Provisional; Region: PRK08898 272560012323 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560012324 FeS/SAM binding site; other site 272560012325 HemN C-terminal domain; Region: HemN_C; pfam06969 272560012326 Pfam match to entry PF02473 Coprogen_an_ox, Oxygen-independent Coproporphyrinogen III oxidase , score -18.9, E-value 2.9e-14 272560012327 Genomic island GI 9; Prophage-like region 272560012328 lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222 272560012329 Signal peptide predicted for BPSL2569 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 18 and 19; signal peptide 272560012330 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 272560012331 Helix-turn-helix domain; Region: HTH_36; pfam13730 272560012332 Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523 272560012333 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 272560012334 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 272560012335 active site 272560012336 Int/Topo IB signature motif; other site 272560012337 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 44.2, E-value 1.9e-10 272560012338 Gene remnant. Similar to internal regions of Ralstonia solanacearum integrase prophage protein rsc1896 or rs03460 SWALL:Q8XY67 (EMBL:AL646067) (411 aa) fasta scores: E(): 3.3e-11, 40.76% id in 157 aa, and Xanthomonas axonopodis phage-related integrase IntA or xac1664 SWALL:Q8PLX5 (EMBL:AE011798) (396 aa) fasta scores: E(): 1.8e-09, 39.74% id in 156 aa; integrase prophage protein (fragment) 272560012339 putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830 272560012340 Signal peptide predicted for BPSL2589 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.321 between residues 38 and 39; signal peptide 272560012341 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012342 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560012343 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560012344 putative substrate translocation pore; other site 272560012345 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 180.5, E-value 1.8e-51 272560012346 11 probable transmembrane helices predicted for BPSL2590 by TMHMM2.0 at aa 33-55, 75-97, 104-126, 175-197, 204-226, 259-281, 294-316, 326-345, 352-374, 384-406 and 413-435 272560012347 PS00216 Sugar transport proteins signature 1. 272560012348 2 probable transmembrane helices predicted for BPSL2591 by TMHMM2.0 at aa 12-31 and 36-58 272560012349 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560012350 putative active site [active] 272560012351 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 126.2, E-value 3.8e-35 272560012352 ClC chloride channel family. These protein sequences, closely related to the ClC Eric family, are putative halogen ion (Cl-, Br- and I-) transport proteins found in eubacteria. They belong to the ClC superfamily of chloride ion channels, which share a...; Region: EriC_like; cd01034 272560012353 putative ion selectivity filter; other site 272560012354 putative pore gating glutamate residue; other site 272560012355 putative H+/Cl- coupling transport residue; other site 272560012356 9 probable transmembrane helices predicted for BPSL2593 by TMHMM2.0 at aa 21-42, 57-74, 161-183, 198-220, 233-255, 275-297, 318-340, 355-377 and 384-406 272560012357 Pfam match to entry PF00654 voltage_CLC, Voltage gated chloride channel , score 79.7, E-value 3.9e-21 272560012358 PS00044 Bacterial regulatory proteins, lysR family signature. 272560012359 Signal peptide predicted for BPSL2594 by SignalP 2.0 HMM (Signal peptide probabilty 0.983) with cleavage site probability 0.847 between residues 45 and 46; signal peptide 272560012360 cell division topological specificity factor MinE; Provisional; Region: PRK13989 272560012361 Pfam match to entry PF03776 MinE, Septum formation topological specificity factor MinE , score 119.7, E-value 3.5e-33 272560012362 Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894 272560012363 Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036 272560012364 P-loop; other site 272560012365 ADP binding residues [chemical binding]; other site 272560012366 Switch I; other site 272560012367 Switch II; other site 272560012368 Pfam match to entry PF00991 ParA, ParA family ATPase , score 29.5, E-value 3.5e-06 272560012369 septum formation inhibitor; Reviewed; Region: PRK01973 272560012370 Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209 272560012371 Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775 272560012372 Pfam match to entry PF03775 MinC, Septum formation inhibitor MinC , score 163.2, E-value 2.8e-46 272560012373 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560012374 Coenzyme A binding pocket [chemical binding]; other site 272560012375 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 56.0, E-value 5.3e-14 272560012376 seryl-tRNA synthetase; Provisional; Region: PRK05431 272560012377 Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403 272560012378 Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770 272560012379 dimer interface [polypeptide binding]; other site 272560012380 active site 272560012381 motif 1; other site 272560012382 motif 2; other site 272560012383 motif 3; other site 272560012384 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T) , score 189.7, E-value 3e-54 272560012385 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560012386 Pfam match to entry PF02403 Seryl_tRNA_N, Seryl-tRNA synthetase N-terminal domain , score 48.1, E-value 1.3e-11 272560012387 Uncharacterized conserved protein (DUF2164); Region: DUF2164; pfam09932 272560012388 recombination factor protein RarA; Reviewed; Region: PRK13342 272560012389 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560012390 Walker A motif; other site 272560012391 ATP binding site [chemical binding]; other site 272560012392 Walker B motif; other site 272560012393 arginine finger; other site 272560012394 MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002 272560012395 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 55.9, E-value 5.5e-14 272560012396 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012397 Signal peptide predicted for BPSL2603 by SignalP 2.0 HMM (Signal peptide probabilty 0.870) with cleavage site probability 0.837 between residues 44 and 45; signal peptide 272560012398 lipoprotein chaperone; Reviewed; Region: lolA; PRK00031 272560012399 Pfam match to entry PF03548 LolA, Outer membrane lipoprotein carrier protein LolA , score 145.3, E-value 7.1e-41 272560012400 Domain of unknown function (DUF4117); Region: DUF4117; pfam13491 272560012401 DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674 272560012402 FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580 272560012403 Ftsk gamma domain; Region: Ftsk_gamma; pfam09397 272560012404 Pfam match to entry PF01580 FtsK_SpoIIIE, FtsK/SpoIIIE family , score 274.6, E-value 8.6e-80 272560012405 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012406 3 probable transmembrane helices predicted for BPSL2604 by TMHMM2.0 at aa 80-97, 122-144 and 218-240 272560012407 Signal peptide predicted for BPSL2605 by SignalP 2.0 HMM (Signal peptide probabilty 0.966) with cleavage site probability 0.906 between residues 25 and 26; signal peptide 272560012408 thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292 272560012409 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560012410 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560012411 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 254.6, E-value 8.7e-74 272560012412 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 272560012413 Smr domain; Region: Smr; cl02619 272560012414 Pfam match to entry PF01713 Smr, Smr domain , score 100.0, E-value 3e-27 272560012415 Signal peptide predicted for BPSL2607 by SignalP 2.0 HMM (Signal peptide probabilty 0.897) with cleavage site probability 0.713 between residues 21 and 22; signal peptide 272560012416 Predicted membrane protein [Function unknown]; Region: COG2860 272560012417 UPF0126 domain; Region: UPF0126; pfam03458 272560012418 UPF0126 domain; Region: UPF0126; pfam03458 272560012419 7 probable transmembrane helices predicted for BPSL2607 by TMHMM2.0 at aa 4-26, 33-52, 67-89, 96-118, 123-145, 158-175 and 179-198 272560012420 Pfam match to entry PF03458 UPF0126, UPF0126 domain , score 47.8, E-value 1.6e-11 272560012421 Pfam match to entry PF03458 UPF0126, UPF0126 domain , score 102.8, E-value 4.2e-28 272560012422 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 272560012423 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 272560012424 Walker A/P-loop; other site 272560012425 ATP binding site [chemical binding]; other site 272560012426 Q-loop/lid; other site 272560012427 ABC transporter signature motif; other site 272560012428 Walker B; other site 272560012429 D-loop; other site 272560012430 H-loop/switch region; other site 272560012431 TOBE domain; Region: TOBE_2; pfam08402 272560012432 Pfam match to entry PF03459 TOBE, TOBE domain , score 24.9, E-value 1e-06 272560012433 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 218.4, E-value 6.8e-63 272560012434 PS00211 ABC transporters family signature. 272560012435 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012436 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 272560012437 Signal peptide predicted for BPSL2609 by SignalP 2.0 HMM (Signal peptide probabilty 0.763) with cleavage site probability 0.338 between residues 36 and 37; signal peptide 272560012438 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560012439 dimer interface [polypeptide binding]; other site 272560012440 conserved gate region; other site 272560012441 putative PBP binding loops; other site 272560012442 ABC-ATPase subunit interface; other site 272560012443 7 probable transmembrane helices predicted for BPSL2609 by TMHMM2.0 at aa 7-29, 84-106, 113-131, 146-165, 186-208, 218-240 and 253-275 272560012444 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 49.9, E-value 3.6e-12 272560012445 PS00070 Aldehyde dehydrogenases cysteine active site. 272560012446 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560012447 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560012448 dimer interface [polypeptide binding]; other site 272560012449 conserved gate region; other site 272560012450 putative PBP binding loops; other site 272560012451 ABC-ATPase subunit interface; other site 272560012452 6 probable transmembrane helices predicted for BPSL2610 by TMHMM2.0 at aa 32-54, 90-112, 124-146, 175-197, 231-253 and 281-303 272560012453 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 46.6, E-value 3.5e-11 272560012454 Signal peptide predicted for BPSL2611 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.944 between residues 24 and 25; signal peptide 272560012455 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560012456 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 272560012457 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 127.6, E-value 1.4e-35 272560012458 glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722 272560012459 Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479 272560012460 Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781 272560012461 Pfam match to entry PF00479 G6PD, Glucose-6-phosphate dehydrogenase, NAD binding domain , score 207.2, E-value 1.6e-59 272560012462 PS00069 Glucose-6-phosphate dehydrogenase active site. 272560012463 Pfam match to entry PF02781 G6PD_C, Glucose-6-phosphate dehydrogenase, C-terminal domain , score 489.5, E-value 1.7e-144 272560012464 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400 272560012465 putative active site [active] 272560012466 bifunctional glucokinase/RpiR family transcriptional regulator; Provisional; Region: PRK14101 272560012467 Glucokinase; Region: Glucokinase; pfam02685 272560012468 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560012469 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560012470 putative active site [active] 272560012471 Pfam match to entry PF02685 Glucokinase, Glucokinase , score 395.2, E-value 4.1e-116 272560012472 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 80.9, E-value 1.7e-21 272560012473 Predicted helix-turn-helix motif with score 1301.000, SD 3.62 at aa 375-396, sequence DPIVDIARKADVSQPTVIRFCR 272560012474 PS00356 Bacterial regulatory proteins, lacI family signature. 272560012475 Pfam match to entry PF01380 SIS, SIS domain , score 77.5, E-value 1.8e-20 272560012476 Signal peptide predicted for BPSL2615 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 26 and 27; signal peptide 272560012477 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560012478 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560012479 substrate binding pocket [chemical binding]; other site 272560012480 membrane-bound complex binding site; other site 272560012481 hinge residues; other site 272560012482 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 267.6, E-value 1.1e-77 272560012483 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560012484 ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765 272560012485 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560012486 dimer interface [polypeptide binding]; other site 272560012487 conserved gate region; other site 272560012488 putative PBP binding loops; other site 272560012489 ABC-ATPase subunit interface; other site 272560012490 3 probable transmembrane helices predicted for BPSL2616 by TMHMM2.0 at aa 20-42, 49-71 and 181-203 272560012491 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 60.5, E-value 2.4e-15 272560012492 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 272560012493 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560012494 Walker A/P-loop; other site 272560012495 ATP binding site [chemical binding]; other site 272560012496 Q-loop/lid; other site 272560012497 ABC transporter signature motif; other site 272560012498 Walker B; other site 272560012499 D-loop; other site 272560012500 H-loop/switch region; other site 272560012501 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 9.9, E-value 0.018 272560012502 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 216.0, E-value 3.6e-62 272560012503 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012504 PS00211 ABC transporters family signature. 272560012505 D-cysteine desulfhydrase; Validated; Region: PRK03910 272560012506 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560012507 catalytic residue [active] 272560012508 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score -14.6, E-value 3.7e-07 272560012509 Protein of unknown function (DUF3088); Region: DUF3088; pfam11287 272560012510 Signal peptide predicted for BPSL2620 by SignalP 2.0 HMM (Signal peptide probabilty 0.983) with cleavage site probability 0.587 between residues 39 and 40; signal peptide 272560012511 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 272560012512 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560012513 putative substrate translocation pore; other site 272560012514 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -82.7, E-value 6.3e-05 272560012515 12 probable transmembrane helices predicted for BPSL2620 by TMHMM2.0 at aa 13-32, 52-71, 78-100, 104-126, 138-160, 165-187, 216-238, 253-270, 283-305, 310-332, 345-367 and 372-394 272560012516 PS00456 Sodium:solute symporter family signature 1. 272560012517 4 probable transmembrane helices predicted for BPSL2621 by TMHMM2.0 at aa 52-70, 82-104, 132-154 and 161-183 272560012518 PS00211 ABC transporters family signature. 272560012519 glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062 272560012520 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560012521 inhibitor-cofactor binding pocket; inhibition site 272560012522 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560012523 catalytic residue [active] 272560012524 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 386.4, E-value 1.8e-113 272560012525 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560012526 riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326 272560012527 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 272560012528 catalytic motif [active] 272560012529 Zn binding site [ion binding]; other site 272560012530 Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985 272560012531 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region , score 133.9, E-value 1.9e-37 272560012532 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 272560012533 Pfam match to entry PF01872 RibD_C, RibD C-terminal domain , score 208.6, E-value 6.2e-60 272560012534 riboflavin synthase subunit alpha; Provisional; Region: PRK09289 272560012535 Lumazine binding domain; Region: Lum_binding; pfam00677 272560012536 Lumazine binding domain; Region: Lum_binding; pfam00677 272560012537 Pfam match to entry PF00677 Lum_binding, Lumazine binding domain , score 40.0, E-value 3.5e-09 272560012538 Pfam match to entry PF00677 Lum_binding, Lumazine binding domain , score 92.7, E-value 4.9e-25 272560012539 PS00693 Riboflavin synthase alpha chain family signature. 272560012540 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II-like protein; Provisional; Region: PRK14019 272560012541 3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926 272560012542 GTP cyclohydrolase II; Region: GTP_cyclohydro2; pfam00925 272560012543 dimerization interface [polypeptide binding]; other site 272560012544 active site 272560012545 Pfam match to entry PF00926 DHBP_synthase, 3,4-dihydroxy-2-butanone 4-phosphate synthase , score 392.2, E-value 3.2e-115 272560012546 Pfam match to entry PF00925 GTP_cyclohydro2, GTP cyclohydrolase II , score 34.5, E-value 1.2e-11 272560012547 lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209 272560012548 homopentamer interface [polypeptide binding]; other site 272560012549 active site 272560012550 Pfam match to entry PF00885 DMRL_synthase, 6,7-dimethyl-8-ribityllumazine synthase , score 187.5, E-value 1.4e-53 272560012551 transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202 272560012552 putative RNA binding site [nucleotide binding]; other site 272560012553 Pfam match to entry PF01029 NusB, NusB family , score 108.1, E-value 1.1e-29 272560012554 aminotransferase; Validated; Region: PRK07337 272560012555 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560012556 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560012557 homodimer interface [polypeptide binding]; other site 272560012558 catalytic residue [active] 272560012559 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 106.7, E-value 2.9e-29 272560012560 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560012561 Predicted helix-turn-helix motif with score 1129.000, SD 3.03 at aa 279-300, sequence GTFEKLAQNLFICPSALAQHAA 272560012562 Signal peptide predicted for BPSL2630 by SignalP 2.0 HMM (Signal peptide probabilty 0.974) with cleavage site probability 0.418 between residues 29 and 30; signal peptide 272560012563 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 272560012564 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560012565 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560012566 catalytic residue [active] 272560012567 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain , score 46.0, E-value 5.3e-11 272560012568 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012569 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311 272560012570 Pfam match to entry PF01977 UPF0096, VdcC family , score 633.4, E-value 8.4e-188 272560012571 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560012572 LysE type translocator; Region: LysE; cl00565 272560012573 6 probable transmembrane helices predicted for BPSL2632 by TMHMM2.0 at aa 13-35, 42-64, 74-93, 126-148, 158-180 and 193-215 272560012574 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 272560012575 tetramer interface [polypeptide binding]; other site 272560012576 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560012577 catalytic residue [active] 272560012578 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 255.0, E-value 6.8e-74 272560012579 Signal peptide predicted for BPSL2634 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.732 between residues 23 and 24; signal peptide 272560012580 2 probable transmembrane helices predicted for BPSL2634 by TMHMM2.0 at aa 20-42 and 57-79 272560012581 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126 272560012582 Rossmann-like domain; Region: Rossmann-like; pfam10727 272560012583 Domain of unknown function (DUF2520); Region: DUF2520; pfam10728 272560012584 YGGT family; Region: YGGT; pfam02325 272560012585 YGGT family; Region: YGGT; pfam02325 272560012586 Pfam match to entry PF02325 YGGT, YGGT family , score 12.1, E-value 0.00064 272560012587 4 probable transmembrane helices predicted for BPSL2636 by TMHMM2.0 at aa 31-53, 88-110, 123-145 and 188-210 272560012588 Pfam match to entry PF02325 YGGT, YGGT family , score 68.2, E-value 1.2e-17 272560012589 Uncharacterized ACR, COG1993; Region: DUF190; cl00872 272560012590 Pfam match to entry PF02641 DUF190, Uncharacterized ACR, COG1993 , score 25.2, E-value 4.7e-06 272560012591 chromosome condensation membrane protein; Provisional; Region: PRK14196 272560012592 Pfam match to entry PF02537 CRCB, CrcB-like protein , score 107.3, E-value 1.9e-29 272560012593 4 probable transmembrane helices predicted for BPSL2638 by TMHMM2.0 at aa 2-24, 34-56, 65-87 and 97-119 272560012594 Signal peptide predicted for BPSL2639 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.632 between residues 20 and 21; signal peptide 272560012595 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 272560012596 active site 272560012597 catalytic triad [active] 272560012598 calcium binding site [ion binding]; other site 272560012599 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 272560012600 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560012601 S-adenosylmethionine binding site [chemical binding]; other site 272560012602 SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195 272560012603 Pfam match to entry PF02146 SIR2, Sir2 family , score 2.5, E-value 4.8e-11 272560012604 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560012605 S-adenosylmethionine binding site [chemical binding]; other site 272560012606 Pfam match to entry PF02390 Methyltransf_4, methyltransferase , score 282.3, E-value 4.1e-82 272560012607 undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281 272560012608 5 probable transmembrane helices predicted for BPSL2643 by TMHMM2.0 at aa 83-102, 107-129, 187-209, 219-241 and 253-275 272560012609 Pfam match to entry PF02673 BacA, Bacitracin resistance protein BacA , score 138.4, E-value 8.6e-39 272560012610 Pfam match to entry PF02673 BacA, Bacitracin resistance protein BacA , score 17.5, E-value 8.5e-05 272560012611 Signal peptide predicted for BPSL2644 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.759 between residues 30 and 31; signal peptide 272560012612 Protein of unknown function (DUF1439); Region: DUF1439; cl06345 272560012613 Putative zinc- or iron-chelating domain; Region: CxxCxxCC; cl00497 272560012614 Pfam match to entry PF03692 UPF0153, Uncharacterised protein family (UPF0153) , score 156.8, E-value 2.3e-44 272560012615 coproporphyrinogen III oxidase; Provisional; Region: PRK09249 272560012616 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560012617 FeS/SAM binding site; other site 272560012618 HemN C-terminal domain; Region: HemN_C; pfam06969 272560012619 Pfam match to entry PF02473 Coprogen_an_ox, Oxygen-independent Coproporphyrinogen III oxidase , score 490.3, E-value 9.7e-145 272560012620 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560012621 S-adenosylmethionine binding site [chemical binding]; other site 272560012622 Pfam match to entry PF01135 PCMT, Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) , score 65.5, E-value 7.5e-17 272560012623 Pfam match to entry PF00398 RrnaAD, Ribosomal RNA adenine dimethylase , score 33.4, E-value 8.3e-11 272560012624 PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 272560012625 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 272560012626 active site residue [active] 272560012627 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 49.5, E-value 4.8e-12 272560012628 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560012629 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560012630 inhibitor-cofactor binding pocket; inhibition site 272560012631 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560012632 catalytic residue [active] 272560012633 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 424.8, E-value 5.2e-125 272560012634 Signal peptide predicted for BPSL2651 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 between residues 39 and 40; signal peptide 272560012635 Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355 272560012636 putative ligand binding site [chemical binding]; other site 272560012637 Signal peptide predicted for BPSL2652 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.690 between residues 29 and 30; signal peptide 272560012638 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560012639 TM-ABC transporter signature motif; other site 272560012640 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 122.1, E-value 6.6e-34 272560012641 8 probable transmembrane helices predicted for BPSL2652 by TMHMM2.0 at aa 243-265, 270-292, 307-326, 339-361, 385-407, 439-461, 476-498 and 505-524 272560012642 Signal peptide predicted for BPSL2653 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.662 between residues 23 and 24; signal peptide 272560012643 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560012644 TM-ABC transporter signature motif; other site 272560012645 9 probable transmembrane helices predicted for BPSL2653 by TMHMM2.0 at aa 49-71, 81-103, 110-132, 164-186, 193-212, 242-264, 289-311, 331-353 and 366-388 272560012646 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 121.1, E-value 1.4e-33 272560012647 urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411 272560012648 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560012649 Walker A/P-loop; other site 272560012650 ATP binding site [chemical binding]; other site 272560012651 Q-loop/lid; other site 272560012652 ABC transporter signature motif; other site 272560012653 Walker B; other site 272560012654 D-loop; other site 272560012655 H-loop/switch region; other site 272560012656 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 153.6, E-value 2.2e-43 272560012657 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012658 PS00211 ABC transporters family signature. 272560012659 urea ABC transporter, ATP-binding protein UrtE; Region: urea_trans_UrtE; TIGR03410 272560012660 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560012661 Walker A/P-loop; other site 272560012662 ATP binding site [chemical binding]; other site 272560012663 Q-loop/lid; other site 272560012664 ABC transporter signature motif; other site 272560012665 Walker B; other site 272560012666 D-loop; other site 272560012667 H-loop/switch region; other site 272560012668 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 154.1, E-value 1.6e-43 272560012669 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012670 Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones]; Region: UreH; COG0829 272560012671 Pfam match to entry PF01774 UreD, UreD urease accessory protein , score 221.9, E-value 6.1e-64 272560012672 Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390 272560012673 alpha-gamma subunit interface [polypeptide binding]; other site 272560012674 beta-gamma subunit interface [polypeptide binding]; other site 272560012675 Pfam match to entry PF00547 urease_gamma, Urease, gamma subunit , score 235.4, E-value 5.4e-68 272560012676 Urease beta-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use of...; Region: Urease_beta; cd00407 272560012677 gamma-beta subunit interface [polypeptide binding]; other site 272560012678 alpha-beta subunit interface [polypeptide binding]; other site 272560012679 Pfam match to entry PF00699 Urease_beta, Urease beta subunit , score 220.2, E-value 2e-63 272560012680 urease subunit alpha; Reviewed; Region: ureC; PRK13207 272560012681 Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375 272560012682 subunit interactions [polypeptide binding]; other site 272560012683 active site 272560012684 flap region; other site 272560012685 Pfam match to entry PF00449 urease, Urease alpha-subunit, N-terminal domain , score 302.8, E-value 2.7e-88 272560012686 PS01120 Urease nickel ligands signature. 272560012687 Pfam match to entry PF02802 urease_C, Urease alpha-subunit, catalytic domain , score 1172.5, E-value 0 272560012688 PS00145 Urease active site. 272560012689 Signal peptide predicted for BPSL2660 by SignalP 2.0 HMM (Signal peptide probabilty 0.932) with cleavage site probability 0.893 between residues 28 and 29; signal peptide 272560012690 Urease accessory protein UreE [Posttranslational modification, protein turnover, chaperones]; Region: UreE; COG2371 272560012691 UreE urease accessory protein. UreE is a metallochaperone assisting the insertion of a Ni2+ ion in the active site of urease, an important step in the in vivo assembly of urease, an enzyme that hydrolyses urea into ammonia and carbamic acid. The...; Region: UreE; cd00571 272560012692 dimer interface [polypeptide binding]; other site 272560012693 catalytic residues [active] 272560012694 Pfam match to entry PF02814 UreE, UreE urease accessory protein , score 94.1, E-value 1.8e-25 272560012695 UreF; Region: UreF; cl19817 272560012696 Pfam match to entry PF01730 UreF, UreF , score 133.0, E-value 3.5e-37 272560012697 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560012698 Pfam match to entry PF01495 HypB_UreG, HypB/UreG nucleotide-binding domain , score 260.8, E-value 1.2e-75 272560012699 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012700 3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749 272560012701 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413 272560012702 Glycosyl transferases group 1; Region: Glycos_transf_1; cl19138 272560012703 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 24.9, E-value 7.7e-07 272560012704 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase; Region: Kdo_hydroxy; pfam11004 272560012705 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560012706 putative active site [active] 272560012707 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 172.4, E-value 4.8e-49 272560012708 Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109 272560012709 The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089 272560012710 active site 272560012711 substrate binding site [chemical binding]; other site 272560012712 metal binding site [ion binding]; metal-binding site 272560012713 Pfam match to entry PF00408 PGM_PMM, Phosphoglucomutase/phosphomannomutase, C-terminal domain , score 69.1, E-value 6.1e-18 272560012714 Pfam match to entry PF02880 PGM_PMM_III, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III , score 159.0, E-value 5.2e-45 272560012715 Pfam match to entry PF02879 PGM_PMM_II, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II , score 164.8, E-value 9.6e-47 272560012716 Pfam match to entry PF02878 PGM_PMM_I, Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I , score 151.3, E-value 1.1e-42 272560012717 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 272560012718 12 probable transmembrane helices predicted for BPSL2667 by TMHMM2.0 at aa 46-68, 78-100, 113-135, 145-167, 180-202, 207-226, 242-264, 293-312, 325-347, 362-384, 391-411 and 416-438 272560012719 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560012720 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560012721 active site 272560012722 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 55.3, E-value 8.5e-14 272560012723 This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808 272560012724 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560012725 putative ADP-binding pocket [chemical binding]; other site 272560012726 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 117.0, E-value 2.3e-32 272560012727 UDP-glucose 4-epimerase; Region: PLN02240 272560012728 UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247 272560012729 NAD binding site [chemical binding]; other site 272560012730 homodimer interface [polypeptide binding]; other site 272560012731 active site 272560012732 substrate binding site [chemical binding]; other site 272560012733 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 521.1, E-value 5.1e-154 272560012734 This subfamily is composed of uncharacterized bacterial glycosyltransferases in the MraY-like family. This family contains both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases, which...; Region: GT_MraY_like; cd06912 272560012735 Mg++ binding site [ion binding]; other site 272560012736 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380 272560012737 putative catalytic motif [active] 272560012738 11 probable transmembrane helices predicted for BPSL2671 by TMHMM2.0 at aa 5-24, 45-64, 69-91, 100-122, 132-154, 161-183, 193-215, 217-235, 240-262, 306-325 and 329-351 272560012739 Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase , score 46.0, E-value 5.4e-11 272560012740 Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086 272560012741 CoA binding domain; Region: CoA_binding; cl17356 272560012742 UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237 272560012743 NAD(P) binding site [chemical binding]; other site 272560012744 homodimer interface [polypeptide binding]; other site 272560012745 substrate binding site [chemical binding]; other site 272560012746 active site 272560012747 Pfam match to entry PF02719 Polysacc_synt_2, Polysaccharide biosynthesis protein , score 1209.8, E-value 0 272560012748 5 probable transmembrane helices predicted for BPSL2672 by TMHMM2.0 at aa 12-34, 49-68, 81-103, 108-130 and 137-159 272560012749 Signal peptide predicted for BPSL2673 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.537 between residues 23 and 24; signal peptide 272560012750 Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571 272560012751 Mg++ binding site [ion binding]; other site 272560012752 putative catalytic motif [active] 272560012753 10 probable transmembrane helices predicted for BPSL2673 by TMHMM2.0 at aa 13-35, 67-89, 102-119, 124-143, 150-169, 174-193, 200-222, 226-248, 281-303 and 308-330 272560012754 Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase , score 45.1, E-value 1e-10 272560012755 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560012756 UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs; Region: UDP_G4E_4_SDR_e; cd05232 272560012757 putative NAD(P) binding site [chemical binding]; other site 272560012758 active site 272560012759 putative substrate binding site [chemical binding]; other site 272560012760 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560012761 Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186 272560012762 Probable Catalytic site; other site 272560012763 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560012764 metal-binding site 272560012765 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 36.6, E-value 3.7e-08 272560012766 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560012767 Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186 272560012768 Probable Catalytic site; other site 272560012769 metal-binding site 272560012770 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 272560012771 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 272560012772 active site 272560012773 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 98.4, E-value 9.3e-27 272560012774 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 25.5, E-value 8.1e-05 272560012775 Methyltransferase domain; Region: Methyltransf_23; pfam13489 272560012776 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560012777 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 272560012778 active site 272560012779 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 31.3, E-value 1.5e-06 272560012780 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 272560012781 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560012782 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560012783 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560012784 NAD(P) binding site [chemical binding]; other site 272560012785 active site 272560012786 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 120.2, E-value 2.5e-33 272560012787 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560012788 8 probable transmembrane helices predicted for BPSL2680 by TMHMM2.0 at aa 47-69, 84-101, 121-143, 198-220, 227-249, 286-317, 337-356 and 360-382 272560012789 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 26.8, E-value 2.3e-07 272560012790 ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134 272560012791 ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220 272560012792 Walker A/P-loop; other site 272560012793 ATP binding site [chemical binding]; other site 272560012794 Q-loop/lid; other site 272560012795 ABC transporter signature motif; other site 272560012796 Walker B; other site 272560012797 D-loop; other site 272560012798 H-loop/switch region; other site 272560012799 C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147 272560012800 putative carbohydrate binding site [chemical binding]; other site 272560012801 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 149.4, E-value 4e-42 272560012802 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012803 ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682 272560012804 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560012805 Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter , score 372.1, E-value 3.8e-109 272560012806 6 probable transmembrane helices predicted for BPSL2682 by TMHMM2.0 at aa 44-66, 81-100, 121-143, 158-180, 192-214 and 247-266 272560012807 dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254 272560012808 RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321 272560012809 NADP binding site [chemical binding]; other site 272560012810 active site 272560012811 putative substrate binding site [chemical binding]; other site 272560012812 dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; cl17405 272560012813 Pfam match to entry PF00908 dTDP_sugar_isom, dTDP-4-dehydrorhamnose 3,5-epimerase , score 371.4, E-value 6.1e-109 272560012814 G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538 272560012815 glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207 272560012816 substrate binding site; other site 272560012817 tetramer interface; other site 272560012818 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 389.6, E-value 2e-114 272560012819 dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088 272560012820 dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246 272560012821 NAD binding site [chemical binding]; other site 272560012822 substrate binding site [chemical binding]; other site 272560012823 homodimer interface [polypeptide binding]; other site 272560012824 active site 272560012825 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 620.2, E-value 7.9e-184 272560012826 1 probable transmembrane helix predicted for BPSL2686 by TMHMM2.0 at aa 13-32 272560012827 diadenosine tetraphosphatase; Reviewed; Region: apaH; PRK00166 272560012828 Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422 272560012829 active site 272560012830 metal binding site [ion binding]; metal-binding site 272560012831 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 54.5, E-value 1.5e-13 272560012832 Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989 272560012833 putative acyl-acceptor binding pocket; other site 272560012834 Pfam match to entry PF01553 Acyltransferase, Acyltransferase , score 145.6, E-value 5.6e-41 272560012835 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012836 dihydroorotase; Provisional; Region: PRK07627 272560012837 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560012838 Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317 272560012839 active site 272560012840 Pfam match to entry PF00744 Dihydroorotase, Dihydroorotase-like , score 157.9, E-value 1.1e-44 272560012841 aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856 272560012842 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 272560012843 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 272560012844 Pfam match to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain , score 79.0, E-value 6.5e-21 272560012845 Pfam match to entry PF02729 OTCace_N, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain , score 122.2, E-value 6.2e-34 272560012846 PS00097 Aspartate and ornithine carbamoyltransferases signature. 272560012847 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560012848 active site 272560012849 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 33.1, E-value 4.1e-07 272560012850 Holliday junction resolvase-like protein; Reviewed; Region: PRK00109 272560012851 Pfam match to entry PF03652 UPF0081, Uncharacterised protein family (UPF0081) , score 143.0, E-value 3.4e-40 272560012852 hypothetical protein; Validated; Region: PRK00228 272560012853 Pfam match to entry PF02622 DUF179, Uncharacterized ACR, COG1678 , score 205.8, E-value 4.4e-59 272560012854 Rubredoxin [Energy production and conversion]; Region: COG1773 272560012855 Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730 272560012856 iron binding site [ion binding]; other site 272560012857 Pfam match to entry PF00301 rubredoxin, Rubredoxin , score 94.0, E-value 1.9e-25 272560012858 PS00202 Rubredoxin signature. 272560012859 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 272560012860 dimer interface [polypeptide binding]; other site 272560012861 substrate binding site [chemical binding]; other site 272560012862 ATP binding site [chemical binding]; other site 272560012863 chaperonin GroEL; Reviewed; Region: groEL; PRK12850 272560012864 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 272560012865 ring oligomerisation interface [polypeptide binding]; other site 272560012866 ATP/Mg binding site [chemical binding]; other site 272560012867 stacking interactions; other site 272560012868 hinge regions; other site 272560012869 Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family , score 658.4, E-value 2.4e-195 272560012870 PS00296 Chaperonins cpn60 signature. 272560012871 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 272560012872 oligomerisation interface [polypeptide binding]; other site 272560012873 mobile loop; other site 272560012874 roof hairpin; other site 272560012875 Pfam match to entry PF00166 cpn10, Chaperonin 10 Kd subunit , score 214.5, E-value 1e-61 272560012876 PS00681 Chaperonins cpn10 signature. 272560012877 Signal peptide predicted for BPSL2699 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.952 between residues 28 and 29; signal peptide 272560012878 hypothetical protein; Validated; Region: PRK09169 272560012879 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 4.4, E-value 1.9 272560012880 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 4.5, E-value 1.8 272560012881 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 4.5, E-value 1.8 272560012882 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 4.8, E-value 1.7 272560012883 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 3.3, E-value 2.6 272560012884 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 4.5, E-value 1.8 272560012885 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 6.0, E-value 1.2 272560012886 Pfam match to entry PF00514 Armadillo_seg, Armadillo/beta-catenin-like repeat , score 8.8, E-value 0.57 272560012887 Predicted transcriptional regulators [Transcription]; Region: COG1733 272560012888 Pfam match to entry PF01638 DUF24, Transcriptional regulator , score 166.9, E-value 2.3e-47 272560012889 Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR7; cd08276 272560012890 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 272560012891 putative NAD(P) binding site [chemical binding]; other site 272560012892 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 244.1, E-value 1.3e-70 272560012893 1 probable transmembrane helix predicted for BPSL2702 by TMHMM2.0 at aa 244-266 272560012894 Signal peptide predicted for BPSL2703 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.993 between residues 25 and 26; signal peptide 272560012895 Signal peptide predicted for BPSL2704 by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.952 between residues 46 and 47; signal peptide 272560012896 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 272560012897 Pfam match to entry PF03922 OmpW, OmpW family , score 35.8, E-value 8.4e-09 272560012898 Signal peptide predicted for BPSL2705 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.274 between residues 18 and 19; signal peptide 272560012899 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 272560012900 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012901 Signal peptide predicted for BPSL2706 by SignalP 2.0 HMM (Signal peptide probabilty 0.901) with cleavage site probability 0.567 between residues 24 and 25; signal peptide 272560012902 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 272560012903 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012904 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560012905 dimerization interface [polypeptide binding]; other site 272560012906 putative DNA binding site [nucleotide binding]; other site 272560012907 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560012908 putative Zn2+ binding site [ion binding]; other site 272560012909 Pfam match to entry PF01638 DUF24, Transcriptional regulator , score 94.2, E-value 1.7e-25 272560012910 Signal peptide predicted for BPSL2708 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.996 between residues 24 and 25; signal peptide 272560012911 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 272560012912 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 17.2, E-value 8.8e-05 272560012913 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 272560012914 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560012915 non-specific DNA binding site [nucleotide binding]; other site 272560012916 salt bridge; other site 272560012917 sequence-specific DNA binding site [nucleotide binding]; other site 272560012918 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 58.2, E-value 1.2e-14 272560012919 Predicted helix-turn-helix motif with score 1356.000, SD 3.81 at aa 20-41, sequence YSLDALAERSKVSRSNISLIER 272560012920 ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575 272560012921 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560012922 Coenzyme A binding pocket [chemical binding]; other site 272560012923 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 57.0, E-value 2.7e-14 272560012924 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012925 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560012926 Signal peptide predicted for BPSL2711 by SignalP 2.0 HMM (Signal peptide probabilty 0.910) with cleavage site probability 0.794 between residues 25 and 26; signal peptide 272560012927 4 probable transmembrane helices predicted for BPSL2711 by TMHMM2.0 at aa 7-28, 43-65, 149-171 and 186-205 272560012928 Pfam match to entry PF01810 LysE, LysE type translocator , score 38.3, E-value 1.2e-08 272560012929 Signal peptide predicted for BPSL2712 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.453 between residues 23 and 24; signal peptide 272560012930 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 272560012931 Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins; Region: GDPD_ScGlpQ1_like; cd08602 272560012932 putative active site [active] 272560012933 catalytic site [active] 272560012934 putative metal binding site [ion binding]; other site 272560012935 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase , score 184.1, E-value 1.4e-52 272560012936 Signal peptide predicted for BPSL2713 by SignalP 2.0 HMM (Signal peptide probabilty 0.721) with cleavage site probability 0.485 between residues 33 and 34; signal peptide 272560012937 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560012938 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560012939 putative substrate translocation pore; other site 272560012940 14 probable transmembrane helices predicted for BPSL2713 by TMHMM2.0 at aa 12-34, 49-68, 80-102, 106-128, 140-162, 166-188, 200-222, 227-249, 270-292, 302-324, 331-353, 363-385, 398-420 and 440-462 272560012941 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 272560012942 Pfam match to entry PF01925 DUF81, Domain of unknown function DUF81 , score 52.4, E-value 5.3e-15 272560012943 6 probable transmembrane helices predicted for BPSL2714 by TMHMM2.0 at aa 13-35, 74-96, 109-131, 146-180, 193-210 and 215-237 272560012944 Pfam match to entry PF01925 DUF81, Domain of unknown function DUF81 , score 58.7, E-value 8.5e-15 272560012945 Signal peptide predicted for BPSL2715 by SignalP 2.0 HMM (Signal peptide probabilty 0.992) with cleavage site probability 0.439 between residues 48 and 49; signal peptide 272560012946 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 272560012947 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 272560012948 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012949 Signal peptide predicted for BPSL2716 by SignalP 2.0 HMM (Signal peptide probabilty 0.985) with cleavage site probability 0.965 between residues 29 and 30; signal peptide 272560012950 3HB-oligomer hydrolase (3HBOH); Region: 3HBOH; pfam10605 272560012951 Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073 272560012952 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012953 Signal peptide predicted for BPSL2717 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.811 between residues 24 and 25; signal peptide 272560012954 BON domain; Region: BON; pfam04972 272560012955 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560012956 Signal peptide predicted for BPSL2718 by SignalP 2.0 HMM (Signal peptide probabilty 0.891) with cleavage site probability 0.476 between residues 25 and 26; signal peptide 272560012957 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560012958 2 probable transmembrane helices predicted for BPSL2718 by TMHMM2.0 at aa 52-74 and 378-400 272560012959 DsbA family, 2-hydroxychromene-2-carboxylate (HCCA) isomerase subfamily; HCCA isomerase is a glutathione (GSH) dependent enzyme involved in the naphthalene catabolic pathway. It converts HCCA, a hemiketal formed spontaneously after ring cleavage of 1; Region: DsbA_HCCA_Iso; cd03022 272560012960 putative catalytic residue [active] 272560012961 Pfam match to entry PF03046 HCCA_isomerase, 2-hydroxychromene-2-carboxylate isomerase , score 58.8, E-value 7.7e-15 272560012962 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560012963 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560012964 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560012965 dimerization interface [polypeptide binding]; other site 272560012966 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 70.2, E-value 2.8e-18 272560012967 Predicted helix-turn-helix motif with score 1448.000, SD 4.12 at aa 26-47, sequence RSVTQAALRLNQTQPAISAALR 272560012968 PS00044 Bacterial regulatory proteins, lysR family signature. 272560012969 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 76.5, E-value 3.5e-20 272560012970 Signal peptide predicted for BPSL2721 by SignalP 2.0 HMM (Signal peptide probabilty 0.960) with cleavage site probability 0.910 between residues 42 and 43; signal peptide 272560012971 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 272560012972 ABC-ATPase subunit interface; other site 272560012973 dimer interface [polypeptide binding]; other site 272560012974 putative PBP binding regions; other site 272560012975 Pfam match to entry PF01032 FecCD, FecCD transport family , score 290.2, E-value 1.7e-84 272560012976 8 probable transmembrane helices predicted for BPSL2721 by TMHMM2.0 at aa 20-42, 94-116, 129-151, 155-174, 186-208, 226-248, 279-301 and 345-362 272560012977 Signal peptide predicted for BPSL2722 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.800 between residues 39 and 40; signal peptide 272560012978 Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and...; Region: TroA_a; cd01148 272560012979 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 272560012980 putative ligand binding residues [chemical binding]; other site 272560012981 Pfam match to entry PF01497 Peripla_BP_2, Periplasmic binding protein , score 25.0, E-value 4.1e-07 272560012982 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120 272560012983 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 272560012984 Walker A/P-loop; other site 272560012985 ATP binding site [chemical binding]; other site 272560012986 Q-loop/lid; other site 272560012987 ABC transporter signature motif; other site 272560012988 Walker B; other site 272560012989 D-loop; other site 272560012990 H-loop/switch region; other site 272560012991 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 177.1, E-value 1.9e-50 272560012992 PS00211 ABC transporters family signature. 272560012993 PS00017 ATP/GTP-binding site motif A (P-loop). 272560012994 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 272560012995 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560012996 N-terminal plug; other site 272560012997 ligand-binding site [chemical binding]; other site 272560012998 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 57.7, E-value 1.7e-14 272560012999 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460 272560013000 Signal peptide predicted for BPSL2726 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.955 between residues 25 and 26; signal peptide 272560013001 Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531 272560013002 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 21.0, E-value 1.3e-06 272560013003 xanthine dehydrogenase, molybdopterin binding subunit; Region: xanthine_xdhB; TIGR02965 272560013004 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 272560013005 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 272560013006 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain , score 760.8, E-value 3.8e-226 272560013007 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain , score 146.6, E-value 2.8e-41 272560013008 xanthine dehydrogenase, small subunit; Region: xanthine_xdhA; TIGR02963 272560013009 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560013010 catalytic loop [active] 272560013011 iron binding site [ion binding]; other site 272560013012 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 272560013013 FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941 272560013014 CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450 272560013015 Pfam match to entry PF03450 CO_deh_flav_C, CO dehydrogenase flavoprotein C-terminal domain , score 87.7, E-value 1.6e-23 272560013016 Pfam match to entry PF00941 FAD_binding_5, FAD binding domain in molybdopterin dehydrogenase , score 130.5, E-value 2e-36 272560013017 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain , score 144.6, E-value 1.2e-40 272560013018 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 14.6, E-value 0.0011 272560013019 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560013020 major facilitator superfamily transporter; Provisional; Region: PRK05122 272560013021 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560013022 putative substrate translocation pore; other site 272560013023 12 probable transmembrane helices predicted for BPSL2729 by TMHMM2.0 at aa 21-43, 53-75, 88-110, 125-147, 154-176, 181-203, 224-246, 256-275, 282-304, 314-336, 345-367 and 372-394 272560013024 Signal peptide predicted for BPSL2730 by SignalP 2.0 HMM (Signal peptide probabilty 0.965) with cleavage site probability 0.889 between residues 27 and 28; signal peptide 272560013025 putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272 272560013026 EamA-like transporter family; Region: EamA; pfam00892 272560013027 EamA-like transporter family; Region: EamA; pfam00892 272560013028 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 50.9, E-value 1.9e-12 272560013029 10 probable transmembrane helices predicted for BPSL2730 by TMHMM2.0 at aa 12-34, 54-71, 84-106, 110-132, 139-157, 167-189, 202-224, 234-256, 263-281 and 286-305 272560013030 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 80.5, E-value 2.2e-21 272560013031 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560013032 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560013033 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560013034 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 31.1, E-value 1.7e-06 272560013035 Predicted helix-turn-helix motif with score 1336.000, SD 3.74 at aa 244-265, sequence MTLGELAQFASLSEYHFSRMFS 272560013036 PS00041 Bacterial regulatory proteins, araC family signature. 272560013037 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 42.5, E-value 6.3e-10 272560013038 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075 272560013039 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560013040 catalytic residue [active] 272560013041 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 9.2, E-value 6.4e-09 272560013042 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 272560013043 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560013044 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560013045 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560013046 putative effector binding pocket; other site 272560013047 dimerization interface [polypeptide binding]; other site 272560013048 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 69.9, E-value 3.6e-18 272560013049 Predicted helix-turn-helix motif with score 1121.000, SD 3.00 at aa 17-38, sequence QSFRRAARKLGVSNALVTRSIA 272560013050 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 160.0, E-value 2.7e-45 272560013051 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 272560013052 D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183 272560013053 putative ligand binding site [chemical binding]; other site 272560013054 putative NAD binding site [chemical binding]; other site 272560013055 catalytic site [active] 272560013056 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 97.2, E-value 2.1e-26 272560013057 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 324.8, E-value 6.5e-95 272560013058 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013059 PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 272560013060 PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 272560013061 Predicted helix-turn-helix motif with score 1437.000, SD 4.08 at aa 300-321, sequence FTREALAEIAHTTLSNIRAWQD 272560013062 Subfamily of the nitroreductase family that includes BluB protein in Rhodobacter capsulatus is involved in the conversion of cobinamide to cobalamin in Cobalamin (vitamin B12) biosynthesis. Nitroreductases typically reduce their substrates by using NAD(P)...; Region: BluB; cd02145 272560013063 putative FMN binding site [chemical binding]; other site 272560013064 Pfam match to entry PF00881 Nitroreductase, Nitroreductase , score 134.5, E-value 1.3e-37 272560013065 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560013066 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560013067 putative substrate translocation pore; other site 272560013068 12 probable transmembrane helices predicted for BPSL2736 by TMHMM2.0 at aa 5-27, 37-59, 72-94, 99-121, 128-150, 160-179, 200-222, 237-259, 264-286, 291-313, 332-354 and 358-377 272560013069 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -95.1, E-value 0.00017 272560013070 Signal peptide predicted for BPSL2737 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.934 between residues 42 and 43; signal peptide 272560013071 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560013072 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560013073 putative substrate translocation pore; other site 272560013074 12 probable transmembrane helices predicted for BPSL2737 by TMHMM2.0 at aa 20-42, 52-74, 83-102, 107-129, 142-164, 169-188, 214-236, 246-268, 277-296, 301-323, 330-352 and 362-384 272560013075 fumarylacetoacetase; Region: PLN02856 272560013076 Fumarylacetoacetase N-terminal; Region: FAA_hydrolase_N; pfam09298 272560013077 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560013078 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 282.2, E-value 4.3e-82 272560013079 homogentisate 1,2-dioxygenase; Provisional; Region: PRK05341 272560013080 benzoate transport; Region: 2A0115; TIGR00895 272560013081 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560013082 putative substrate translocation pore; other site 272560013083 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 37.1, E-value 4.3e-09 272560013084 12 probable transmembrane helices predicted for BPSL2740 by TMHMM2.0 at aa 28-50, 65-87, 94-116, 120-142, 154-176, 181-203, 263-285, 295-317, 324-343, 348-370, 391-413 and 417-439 272560013085 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 272560013086 PS00217 Sugar transport proteins signature 2. 272560013087 PS00216 Sugar transport proteins signature 1. 272560013088 Protein of unknown function (DUF2783); Region: DUF2783; pfam10932 272560013089 FAD-dependent oxidoreductase; Provisional; Region: PRK08132 272560013090 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560013091 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 127.3, E-value 1.8e-35 272560013092 Pfam match to entry PF01494 FAD_binding_3, FAD binding domain , score 37.3, E-value 1.2e-08 272560013093 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 272560013094 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 49.0, E-value 6.7e-12 272560013095 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cl00290 272560013096 Pfam match to entry PF00563 EAL, EAL domain , score -110.4, E-value 0.001 272560013097 Uncharacterized conserved protein [Function unknown]; Region: COG3791 272560013098 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560013099 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560013100 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560013101 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 51.6, E-value 1.1e-12 272560013102 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 272560013103 Predicted helix-turn-helix motif with score 1019.000, SD 2.66 at aa 48-69, sequence LGNRDFAERTGLPKATVNRLAY 272560013104 Glutaryl-CoA dehydrogenase; Region: GCD; cd01151 272560013105 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560013106 FAD binding site [chemical binding]; other site 272560013107 substrate binding pocket [chemical binding]; other site 272560013108 catalytic base [active] 272560013109 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 95.4, E-value 7.6e-26 272560013110 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 82.3, E-value 6.4e-22 272560013111 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 173.0, E-value 3.3e-49 272560013112 PS00073 Acyl-CoA dehydrogenases signature 2. 272560013113 Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450 272560013114 Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016 272560013115 dimer interface [polypeptide binding]; other site 272560013116 decamer (pentamer of dimers) interface [polypeptide binding]; other site 272560013117 catalytic triad [active] 272560013118 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 215.6, E-value 4.8e-62 272560013119 Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957 272560013120 1 probable transmembrane helix predicted for BPSL2749 by TMHMM2.0 at aa 80-97 272560013121 Predicted membrane protein [Function unknown]; Region: COG5393 272560013122 2 probable transmembrane helices predicted for BPSL2750 by TMHMM2.0 at aa 47-69 and 79-98 272560013123 Protein of unknown function (DUF3318); Region: DUF3318; pfam11780 272560013124 Signal peptide predicted for BPSL2752 by SignalP 2.0 HMM (Signal peptide probability 0.836) with cleavage site probability 0.816 between residues 32 and 33; signal peptide 272560013125 Tfp pilus assembly protein PilE [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilE; COG4968 272560013126 1 probable transmembrane helix predicted for BPSL2752 by TMHMM2.0 at aa 13-35 272560013127 PS00409 Prokaryotic N-terminal methylation site. 272560013128 Tfp pilus assembly protein PilX [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilX; COG4726 272560013129 1 probable transmembrane helix predicted for BPSL2753 by TMHMM2.0 at aa 36-58 272560013130 Tfp pilus assembly protein PilW [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilW; COG4966 272560013131 1 probable transmembrane helix predicted for BPSL2754 by TMHMM2.0 at aa 12-34 272560013132 Signal peptide predicted for BPSL2755 by SignalP 2.0 HMM (Signal peptide probabilty 0.978) with cleavage site probability 0.819 between residues 36 and 37; signal peptide 272560013133 Signal peptide predicted for BPSL2739 by SignalP 2.0 HMM (Signal peptide probability 0.880) with cleavage site probability 0.623 between residues 37 and 38); signal peptide 272560013134 Type II transport protein GspH; Region: GspH; pfam12019 272560013135 transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464 272560013136 ATP cone domain; Region: ATP-cone; pfam03477 272560013137 Pfam match to entry PF03477 ATP-cone, ATP cone domain , score 101.8, E-value 9e-28 272560013138 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 272560013139 dimer interface [polypeptide binding]; other site 272560013140 Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212 272560013141 active site 272560013142 glycine-pyridoxal phosphate binding site [chemical binding]; other site 272560013143 folate binding site [chemical binding]; other site 272560013144 Pfam match to entry PF00464 SHMT, Serine hydroxymethyltransferase , score 864.8, E-value 1.8e-257 272560013145 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 272560013146 malonic semialdehyde reductase; Provisional; Region: PRK10538 272560013147 classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346 272560013148 Signal peptide predicted for BPSL2759 by SignalP 2.0 HMM (Signal peptide probabilty 0.813) with cleavage site probability 0.368 between residues 19 and 20; signal peptide 272560013149 putative NAD(P) binding site [chemical binding]; other site 272560013150 homodimer interface [polypeptide binding]; other site 272560013151 homotetramer interface [polypeptide binding]; other site 272560013152 active site 272560013153 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 197.8, E-value 1.1e-56 272560013154 PS00061 Short-chain dehydrogenases/reductases family signature. 272560013155 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 272560013156 active site 272560013157 Pfam match to entry PF03061 4HBT, 4-hydroxybenzoyl-CoA thioesterase , score 140.0, E-value 2.7e-39 272560013158 TolQ protein; Region: tolQ; TIGR02796 272560013159 3 probable transmembrane helices predicted for BPSL2761 by TMHMM2.0 at aa 54-76, 168-190 and 210-232 272560013160 Pfam match to entry PF01618 MotA_ExbB, MotA/TolQ/ExbB proton channel family , score 176.1, E-value 3.7e-50 272560013161 TolR protein; Region: tolR; TIGR02801 272560013162 Pfam match to entry PF02472 ExbD, Biopolymer transport protein ExbD/TolR , score 83.7, E-value 2.4e-22 272560013163 TolA protein; Region: tolA_full; TIGR02794 272560013164 TonB C terminal; Region: TonB_2; pfam13103 272560013165 1 probable transmembrane helix predicted for BPSL2763 by TMHMM2.0 at aa 21-43 272560013166 translocation protein TolB; Provisional; Region: tolB; PRK02889 272560013167 Signal peptide predicted for BPSL2764 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27; signal peptide 272560013168 TolB amino-terminal domain; Region: TolB_N; pfam04052 272560013169 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 272560013170 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 272560013171 WD40-like Beta Propeller Repeat; Region: PD40; pfam07676 272560013172 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 272560013173 Signal peptide predicted for BPSL2765 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.442 between residues 19 and 20; signal peptide 272560013174 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560013175 ligand binding site [chemical binding]; other site 272560013176 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013177 Pfam match to entry PF00691 OmpA, OmpA family , score 144.3, E-value 1.4e-40 272560013178 PS01068 OmpA-like domain. 272560013179 Signal peptide predicted for BPSL2766 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 28 and 29; signal peptide 272560013180 Bacterial protein of unknown function (DUF881); Region: DUF881; cl19849 272560013181 tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795 272560013182 Tetratricopeptide repeat; Region: TPR_6; pfam13174 272560013183 Probable gene remnant. Similar to Shigella flexneri orf, partial conserved hypothetical protein sf2566 SWALL:Q83K41 (EMBL:AE015272) (138 aa) fasta scores: E(): 3.4e-12, 72.3% id in 65 aa, and to Escherichia coli IS110 transposase s0055 SWALL:Q8GA45 (EMBL:AJ488511) (398 aa) fasta scores: E(): 4.1e-12, 72.3% id in 65 aa; transposase (fragment) 272560013184 Partial CDS. Similar to Escherichia coli, and Escherichia coli O6 flagellar transcriptional activator FlhD or FlbB or b1892 or c2308 SWALL:FLHD_ECOLI (SWALL:P11164) (119 aa) fasta scores: E(): 0.00099, 37.31% id in 67 aa, and to Ralstonia solanacearum probable flagellar transcriptional activator transcription regulator protein FlhD or rsp1413 or rs03127 SWALL:Q8XQ73 (EMBL:AL646084) (105 aa) fasta scores: E(): 6.4e-05, 42.25% id in 71 aa. The CDS is truncated at the C-terminus; flagellar transcriptional activator (fragment) 272560013185 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 272560013186 active site 272560013187 tetramer interface; other site 272560013188 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 55.1, E-value 1e-13 272560013189 D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892 272560013190 KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014 272560013191 putative active site [active] 272560013192 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 272560013193 Pfam match to entry PF00571 CBS, CBS domain , score 15.4, E-value 0.039 272560013194 Pfam match to entry PF00571 CBS, CBS domain , score 21.6, E-value 0.0012 272560013195 Pfam match to entry PF01380 SIS, SIS domain , score 143.3, E-value 2.9e-40 272560013196 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560013197 active site 272560013198 motif I; other site 272560013199 motif II; other site 272560013200 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 18.4, E-value 6.9e-05 272560013201 2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK12457 272560013202 Pfam match to entry PF00793 DAHP_synth_1, DAHP synthetase I family , score 377.0, E-value 1.2e-110 272560013203 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560013204 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560013205 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 82.3, E-value 6.5e-22 272560013206 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560013207 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560013208 putative acyl transferase; Provisional; Region: PRK10191 272560013209 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 272560013210 trimer interface [polypeptide binding]; other site 272560013211 active site 272560013212 substrate binding site [chemical binding]; other site 272560013213 CoA binding site [chemical binding]; other site 272560013214 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 5.5, E-value 9.4 272560013215 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 22.8, E-value 0.00053 272560013216 1 probable transmembrane helix predicted for BPSL2775 by TMHMM2.0 at aa 43-65 272560013217 Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; cl19502 272560013218 Polysaccharide biosynthesis C-terminal domain; Region: Polysacc_synt_C; cl10513 272560013219 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 272560013220 12 probable transmembrane helices predicted for BPSL2777 by TMHMM2.0 at aa 7-29, 39-61, 73-95, 100-122, 134-153, 163-185, 205-227, 242-261, 281-303, 318-340, 353-375 and 385-407 272560013221 tyrosine kinase; Provisional; Region: PRK11519 272560013222 Chain length determinant protein; Region: Wzz; pfam02706 272560013223 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 272560013224 AAA domain; Region: AAA_31; pfam13614 272560013225 Pfam match to entry PF02706 wzz, Chain length determinant protein , score 175.2, E-value 7.2e-50 272560013226 1 probable transmembrane helix predicted for BPSL2778 by TMHMM2.0 at aa 32-51 272560013227 Low molecular weight phosphatase family; Region: LMWPc; cd00115 272560013228 active site 272560013229 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase , score 137.9, E-value 1.2e-38 272560013230 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 272560013231 polysaccharide export protein EpsE; Region: EpsE; TIGR03028 272560013232 Pfam match to entry PF02563 Poly_export, Polysaccharide biosynthesis/export protein , score 93.2, E-value 3.3e-25 272560013233 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013234 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025 272560013235 CoA binding domain; Region: CoA_binding; cl17356 272560013236 Bacterial sugar transferase; Region: Bac_transf; pfam02397 272560013237 Pfam match to entry PF02397 Bact_transf, Bacterial sugar transferase , score 422.7, E-value 2.1e-124 272560013238 5 probable transmembrane helices predicted for BPSL2781 by TMHMM2.0 at aa 21-42, 52-74, 86-108, 123-145 and 182-203 272560013239 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560013240 Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020 272560013241 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560013242 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560013243 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 35.2, E-value 9.4e-08 272560013244 PS00041 Bacterial regulatory proteins, araC family signature. 272560013245 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.0, E-value 1.4e-08 272560013246 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 272560013247 active site 272560013248 Pfam match to entry PF01569 PAP2, PAP2 superfamily , score 12.1, E-value 0.00026 272560013249 5 probable transmembrane helices predicted for BPSL2783 by TMHMM2.0 at aa 10-32, 45-67, 72-90, 99-116 and 126-148 272560013250 10 probable transmembrane helices predicted for BPSL2784 by TMHMM2.0 at aa 52-74, 78-97, 104-123, 133-152, 164-186, 217-239, 248-270, 285-302, 364-386 and 406-425 272560013251 Signal peptide predicted for BPSL2785 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.559 between residues 21 and 22; signal peptide 272560013252 BNR repeat-like domain; Region: BNR_2; pfam13088 272560013253 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 14.1, E-value 0.22 272560013254 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 17.3, E-value 0.024 272560013255 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560013256 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 22.5, E-value 7.6e-08 272560013257 8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858 272560013258 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 272560013259 substrate-cofactor binding pocket; other site 272560013260 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560013261 catalytic residue [active] 272560013262 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 83.0, E-value 4.1e-22 272560013263 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: PRK13187 272560013264 UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331 272560013265 Pfam match to entry PF03331 LpxC, UDP-3-O-acyl N-acetylglycosamine deacetylase , score 131.8, E-value 8e-37 272560013266 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 272560013267 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560013268 active site 272560013269 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 272560013270 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560013271 Methyltransferase domain; Region: Methyltransf_12; pfam08242 272560013272 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560013273 enoyl reductase of polyketide synthase; Region: enoyl_red; cd05195 272560013274 Enoylreductase; Region: PKS_ER; smart00829 272560013275 NAD(P) binding site [chemical binding]; other site 272560013276 short chain dehydrogenase; Region: adh_short; pfam00106 272560013277 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560013278 NAD(P) binding site [chemical binding]; other site 272560013279 active site 272560013280 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560013281 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 29.8, E-value 4.2e-06 272560013282 PS00012 Phosphopantetheine attachment site. 272560013283 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 256.5, E-value 2.3e-74 272560013284 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 265.8, E-value 3.8e-77 272560013285 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 259.5, E-value 2.9e-75 272560013286 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 414.8, E-value 5.3e-122 272560013287 PS00606 Beta-ketoacyl synthases active site. 272560013288 Signal peptide predicted for BPSL2790 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.720 between residues 18 and 19; signal peptide 272560013289 Sulfatase; Region: Sulfatase; pfam00884 272560013290 5 probable transmembrane helices predicted for BPSL2790 by TMHMM2.0 at aa 7-29, 34-53, 60-82, 107-129 and 142-161 272560013291 short chain dehydrogenase; Provisional; Region: PRK07024 272560013292 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560013293 NAD(P) binding site [chemical binding]; other site 272560013294 active site 272560013295 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 85.1, E-value 9.6e-23 272560013296 PS00061 Short-chain dehydrogenases/reductases family signature. 272560013297 Signal peptide predicted for BPSL2792 by SignalP 2.0 HMM (Signal peptide probabilty 0.872) with cleavage site probability 0.793 between residues 20 and 21; signal peptide 272560013298 Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562 272560013299 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560013300 active site 272560013301 motif I; other site 272560013302 motif II; other site 272560013303 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208 272560013304 WcbM_like is a subfamily of nucleotidyl transferases; Region: NTP_transferase_WcbM_like; cd06915 272560013305 Substrate binding site; other site 272560013306 Mg++ binding site; other site 272560013307 metal-binding site 272560013308 Mg++ binding site; other site 272560013309 metal-binding site 272560013310 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 40.9, E-value 6.5e-11 272560013311 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560013312 Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006 272560013313 dimer interface [polypeptide binding]; other site 272560013314 active site 272560013315 Pfam match to entry PF01380 SIS, SIS domain , score 94.6, E-value 1.3e-25 272560013316 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013317 Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605 272560013318 GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288 272560013319 GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544 272560013320 Pfam match to entry PF00288 GHMP_kinases, GHMP kinases ATP-binding protein , score 97.3, E-value 1.9e-26 272560013321 GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089 272560013322 GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260 272560013323 NADP-binding site; other site 272560013324 homotetramer interface [polypeptide binding]; other site 272560013325 substrate binding site [chemical binding]; other site 272560013326 homodimer interface [polypeptide binding]; other site 272560013327 active site 272560013328 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 49.0, E-value 2.4e-16 272560013329 PS00061 Short-chain dehydrogenases/reductases family signature. 272560013330 dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091 272560013331 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560013332 NAD(P) binding site [chemical binding]; other site 272560013333 active site 272560013334 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560013335 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560013336 Domain of unknown function (DUF4214); Region: DUF4214; pfam13946 272560013337 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 46.8, E-value 3.2e-11 272560013338 Sulfotransferase family; Region: Sulfotransfer_2; cl19526 272560013339 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 272560013340 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560013341 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 63.0, E-value 4.2e-16 272560013342 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 272560013343 ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220 272560013344 Walker A/P-loop; other site 272560013345 ATP binding site [chemical binding]; other site 272560013346 Q-loop/lid; other site 272560013347 ABC transporter signature motif; other site 272560013348 Walker B; other site 272560013349 D-loop; other site 272560013350 H-loop/switch region; other site 272560013351 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 89.6, E-value 4.2e-24 272560013352 PS00211 ABC transporters family signature. 272560013353 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013354 ABC-2 type transporter; Region: ABC2_membrane; cl17235 272560013355 ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698 272560013356 Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter , score 130.2, E-value 2.5e-36 272560013357 6 probable transmembrane helices predicted for BPSL2805 by TMHMM2.0 at aa 23-45, 50-72, 101-123, 138-160, 173-195 and 221-243 272560013358 PS00890 ABC-2 type transport system integral membrane proteins signature. 272560013359 Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsE; COG3524 272560013360 Chain length determinant protein; Region: Wzz; cl19730 272560013361 2 probable transmembrane helices predicted for BPSL2806 by TMHMM2.0 at aa 158-180 and 488-510 272560013362 Gene remnant. Similar to C-terminal reion of Salmonella typhimurium phosphomannomutase ManB or CpsG or RfbL SWALL:MANB_SALTY (SWALL:P26341) (456 aa) fasta scores: E(): 0.8, 30.55% id in 72 aa;phosphomannomutase (fragment) 272560013363 Signal peptide predicted for BPSL2807 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.467 between residues 39 and 40; signal peptide 272560013364 Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596 272560013365 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 272560013366 Pfam match to entry PF02563 Poly_export, Polysaccharide biosynthesis/export protein , score -29.3, E-value 5.8e-06 272560013367 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013368 This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809 272560013369 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560013370 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 45.1, E-value 1e-10 272560013371 Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563 272560013372 Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; cl19502 272560013373 Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159 272560013374 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560013375 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 272560013376 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 272560013377 Substrate binding site; other site 272560013378 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 272560013379 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 357.9, E-value 7.1e-105 272560013380 Pfam match to entry PF01050 MannoseP_isomer, Mannose-6-phosphate isomerase , score 414.0, E-value 8.9e-122 272560013381 Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908 272560013382 putative active site [active] 272560013383 putative dimer interface [polypeptide binding]; other site 272560013384 mechanosensitive channel MscS; Provisional; Region: PRK10334 272560013385 Mechanosensitive ion channel; Region: MS_channel; pfam00924 272560013386 3 probable transmembrane helices predicted for BPSL2812 by TMHMM2.0 at aa 32-54, 75-97 and 102-124 272560013387 Pfam match to entry PF00924 MS_channel, Mechanosensitive ion channel , score 149.9, E-value 2.9e-42 272560013388 SNARE associated Golgi protein; Region: SNARE_assoc; cl00429 272560013389 4 probable transmembrane helices predicted for BPSL2813 by TMHMM2.0 at aa 48-70, 90-112, 180-202 and 212-234 272560013390 Pfam match to entry PF00597 DedA, DedA family , score 114.3, E-value 1.5e-31 272560013391 DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095 272560013392 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560013393 ATP binding site [chemical binding]; other site 272560013394 Mg2+ binding site [ion binding]; other site 272560013395 G-X-G motif; other site 272560013396 MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL. EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482 272560013397 ATP binding site [chemical binding]; other site 272560013398 MutL C terminal dimerization domain; Region: MutL_C; pfam08676 272560013399 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 36.3, E-value 4.4e-08 272560013400 PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 272560013401 Pfam match to entry PF01119 DNA_mis_repair, DNA mismatch repair protein, C-terminal domain , score 117.4, E-value 1.7e-32 272560013402 tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091 272560013403 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013404 Pfam match to entry PF01715 IPPT, IPP transferase , score 385.7, E-value 3.1e-113 272560013405 Ketosteroid isomerase homolog [Function unknown]; Region: COG4319 272560013406 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560013407 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560013408 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560013409 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560013410 Pfam match to entry PF01610 Transposase_12, Transposase , score 371.8, E-value 4.5e-109 272560013411 phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385 272560013412 PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196 272560013413 dimerization interface [polypeptide binding]; other site 272560013414 putative ATP binding site [chemical binding]; other site 272560013415 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain , score 182.9, E-value 3.3e-52 272560013416 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain , score 243.3, E-value 2.2e-70 272560013417 ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593 272560013418 DnaA regulatory inactivator Hda; Validated; Region: PRK08903 272560013419 Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560 272560013420 poly(A) polymerase; Region: pcnB; TIGR01942 272560013421 Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398 272560013422 active site 272560013423 NTP binding site [chemical binding]; other site 272560013424 metal binding triad [ion binding]; metal-binding site 272560013425 Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627 272560013426 Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626 272560013427 Pfam match to entry PF01743 PolyA_pol, Poly A polymerase , score 192.0, E-value 6.3e-55 272560013428 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483 272560013429 catalytic center binding site [active] 272560013430 ATP binding site [chemical binding]; other site 272560013431 Pfam match to entry PF01288 HPPK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) , score 155.4, E-value 6.6e-44 272560013432 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013433 PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 272560013434 Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428 272560013435 Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673 272560013436 Substrate-binding site [chemical binding]; other site 272560013437 Substrate specificity [chemical binding]; other site 272560013438 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013439 Pfam match to entry PF01712 dNK, Deoxynucleoside kinase , score 49.8, E-value 3.9e-12 272560013440 Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557 272560013441 oligomerization interface [polypeptide binding]; other site 272560013442 active site 272560013443 metal binding site [ion binding]; metal-binding site 272560013444 Pfam match to entry PF02548 Pantoate_transf, Ketopantoate hydroxymethyltransferase , score 467.5, E-value 7.3e-138 272560013445 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013446 aminodeoxychorismate synthase, component I, clade 2; Region: PabB-clade2; TIGR01824 272560013447 chorismate binding enzyme; Region: Chorismate_bind; cl10555 272560013448 PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224 272560013449 homodimer interface [polypeptide binding]; other site 272560013450 substrate-cofactor binding pocket; other site 272560013451 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560013452 catalytic residue [active] 272560013453 Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV , score 18.6, E-value 3.4e-05 272560013454 Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme , score 251.9, E-value 5.9e-73 272560013455 chaperone protein DnaJ; Provisional; Region: PRK10767 272560013456 DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257 272560013457 HSP70 interaction site [polypeptide binding]; other site 272560013458 C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747 272560013459 substrate binding site [polypeptide binding]; other site 272560013460 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719 272560013461 Zn binding sites [ion binding]; other site 272560013462 dimer interface [polypeptide binding]; other site 272560013463 Pfam match to entry PF01556 DnaJ_C, DnaJ C terminal region , score 266.7, E-value 2.1e-77 272560013464 Pfam match to entry PF00684 DnaJ_CXXCXGXG, DnaJ central domain (4 repeats) , score 145.3, E-value 7.2e-41 272560013465 PS00190 Cytochrome c family heme-binding site signature. 272560013466 PS00637 CXXCXGXG dnaJ domain signature. 272560013467 PS00190 Cytochrome c family heme-binding site signature. 272560013468 Pfam match to entry PF00226 DnaJ, DnaJ domain , score 143.1, E-value 3.2e-40 272560013469 PS00636 Nt-dnaJ domain signature. 272560013470 molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290 272560013471 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 272560013472 nucleotide binding site [chemical binding]; other site 272560013473 Pfam match to entry PF00012 HSP70, Hsp70 protein , score 1343.8, E-value 0 272560013474 PS01036 Heat shock hsp70 proteins family signature 3. 272560013475 PS00329 Heat shock hsp70 proteins family signature 2. 272560013476 PS00297 Heat shock hsp70 proteins family signature 1. 272560013477 Possible pseudogene. Similar to Ralstonia solanacearum thioredoxin protein rsc2638 or rs04583 SWALL:Q8XW37 (EMBL:AL646071) to codon 106 (140 aa) fasta scores: E(): 1.6e-26, 60% id in 120 aa. CDS may be truncated at this codon. A stop codon (TGA) is present at codon 107. CDS may continue past the stop codon to codon 143;conserved hypothetical protein (pseudogene) 272560013478 GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446 272560013479 dimer interface [polypeptide binding]; other site 272560013480 hsp70 (ATPase domain) interactions [polypeptide binding]; other site 272560013481 Pfam match to entry PF01025 GrpE, GrpE , score 191.4, E-value 9.4e-55 272560013482 PS01071 grpE protein signature. 272560013483 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560013484 RNA binding surface [nucleotide binding]; other site 272560013485 Pfam match to entry PF01479 S4, S4 domain , score 48.6, E-value 9e-12 272560013486 ferrochelatase; Reviewed; Region: hemH; PRK00035 272560013487 Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411 272560013488 C-terminal domain interface [polypeptide binding]; other site 272560013489 active site 272560013490 Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419 272560013491 active site 272560013492 N-terminal domain interface [polypeptide binding]; other site 272560013493 Pfam match to entry PF00762 Ferrochelatase, Ferrochelatase , score 411.1, E-value 6.7e-121 272560013494 PS00534 Ferrochelatase signature. 272560013495 heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082 272560013496 Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444 272560013497 HrcA protein C terminal domain; Region: HrcA; pfam01628 272560013498 Pfam match to entry PF01628 HrcA, HrcA protein C terminal domain , score 175.9, E-value 4.3e-50 272560013499 NAD(+)/NADH kinase family protein; Provisional; Region: ppnK; PRK02155 272560013500 Pfam match to entry PF01513 NAD_kinase, ATP-NAD kinase , score 258.6, E-value 5.4e-75 272560013501 ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497 272560013502 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 272560013503 Walker A/P-loop; other site 272560013504 ATP binding site [chemical binding]; other site 272560013505 Q-loop/lid; other site 272560013506 ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241 272560013507 ABC transporter signature motif; other site 272560013508 Walker B; other site 272560013509 D-loop; other site 272560013510 H-loop/switch region; other site 272560013511 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013512 bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072 272560013513 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 272560013514 metal binding triad; other site 272560013515 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335 272560013516 Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401 272560013517 metal binding triad; other site 272560013518 GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; cl19627 272560013519 Pfam match to entry PF03710 GlnE, Glutamate-ammonia ligase adenylyltransferase , score 261.1, E-value 9.9e-76 272560013520 Pfam match to entry PF03710 GlnE, Glutamate-ammonia ligase adenylyltransferase , score 267.4, E-value 1.2e-77 272560013521 TIGR02099 family protein; Region: TIGR02099 272560013522 Protein of unknown function; Region: DUF3971; pfam13116 272560013523 AsmA-like C-terminal region; Region: AsmA_2; pfam13502 272560013524 1 probable transmembrane helix predicted for BPSL2836 by TMHMM2.0 at aa 30-52 272560013525 Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572 272560013526 putative active site [active] 272560013527 catalytic triad [active] 272560013528 dimer interface [polypeptide binding]; other site 272560013529 Pfam match to entry PF00795 CN_hydrolase, Carbon-nitrogen hydrolase , score 257.0, E-value 1.6e-74 272560013530 Putative modulator of DNA gyrase; Region: PmbA_TldD; cl19356 272560013531 Pfam match to entry PF01523 PmbA_TldD, modulator of DNA gyrase , score 305.2, E-value 5.3e-89 272560013532 phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261 272560013533 Pfam match to entry PF00793 DAHP_synth_1, DAHP synthetase I family , score 546.4, E-value 1.3e-161 272560013534 bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289 272560013535 Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040 272560013536 heme-binding site [chemical binding]; other site 272560013537 FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184 272560013538 FAD binding pocket [chemical binding]; other site 272560013539 FAD binding motif [chemical binding]; other site 272560013540 phosphate binding motif [ion binding]; other site 272560013541 beta-alpha-beta structure motif; other site 272560013542 NAD binding pocket [chemical binding]; other site 272560013543 Heme binding pocket [chemical binding]; other site 272560013544 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 47.3, E-value 2.3e-11 272560013545 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 10.9, E-value 7.4e-05 272560013546 Pfam match to entry PF00042 globin, Globin , score 72.3, E-value 6.8e-19 272560013547 PS00211 ABC transporters family signature. 272560013548 ATP:cob(I)alamin adenosyltransferase; Region: PduO_Nterm; TIGR00636 272560013549 Pfam match to entry PF01923 DUF80, Protein of unknown function DUF80 , score 234.4, E-value 1.1e-67 272560013550 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560013551 FAD binding domain; Region: FAD_binding_4; pfam01565 272560013552 FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913 272560013553 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 227.0, E-value 1.8e-65 272560013554 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 270.5, E-value 1.5e-78 272560013555 glycolate oxidase subunit GlcD; Provisional; Region: PRK11230 272560013556 FAD binding domain; Region: FAD_binding_4; pfam01565 272560013557 FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913 272560013558 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 209.1, E-value 4.4e-60 272560013559 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 235.0, E-value 7e-68 272560013560 FAD binding domain; Region: FAD_binding_4; pfam01565 272560013561 glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282 272560013562 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 93.9, E-value 2.1e-25 272560013563 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 19.4, E-value 1.4e-05 272560013564 glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274 272560013565 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560013566 Cysteine-rich domain; Region: CCG; pfam02754 272560013567 Cysteine-rich domain; Region: CCG; pfam02754 272560013568 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 13.4, E-value 0.0014 272560013569 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560013570 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 13.7, E-value 0.0012 272560013571 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560013572 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 41.9, E-value 9.1e-10 272560013573 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 52.0, E-value 8.5e-13 272560013574 Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824 272560013575 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560013576 catalytic residue [active] 272560013577 Pfam match to entry PF01168 UPF0001, Uncharacterized protein family UPF0001 , score 435.6, E-value 2.8e-128 272560013578 PS01211 Uncharacterized protein family UPF0001 signature. 272560013579 pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880 272560013580 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807 272560013581 Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748 272560013582 Pfam match to entry PF01089 P5CR, Delta 1-pyrroline-5-carboxylate reductase , score 307.6, E-value 1e-89 272560013583 PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 272560013584 phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097 272560013585 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560013586 dimer interface [polypeptide binding]; other site 272560013587 conserved gate region; other site 272560013588 putative PBP binding loops; other site 272560013589 ABC-ATPase subunit interface; other site 272560013590 6 probable transmembrane helices predicted for BPSL2848 by TMHMM2.0 at aa 27-44, 82-104, 133-155, 191-208, 215-237 and 247-266 272560013591 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 34.7, E-value 1.3e-07 272560013592 Signal peptide predicted for BPSL2849 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 22 and 23; signal peptide 272560013593 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560013594 ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221 272560013595 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013596 ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638 272560013597 ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256 272560013598 Walker A/P-loop; other site 272560013599 ATP binding site [chemical binding]; other site 272560013600 Q-loop/lid; other site 272560013601 ABC transporter signature motif; other site 272560013602 Walker B; other site 272560013603 D-loop; other site 272560013604 H-loop/switch region; other site 272560013605 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 188.1, E-value 8.9e-54 272560013606 PS00211 ABC transporters family signature. 272560013607 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013608 phosphonate metabolism protein PhnM; Provisional; Region: PRK15446 272560013609 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560013610 PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306 272560013611 active site 272560013612 phosphonate C-P lyase system protein PhnL; Region: CP_lyasePhnL; TIGR02324 272560013613 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560013614 Walker A/P-loop; other site 272560013615 ATP binding site [chemical binding]; other site 272560013616 Q-loop/lid; other site 272560013617 ABC transporter signature motif; other site 272560013618 Walker B; other site 272560013619 D-loop; other site 272560013620 H-loop/switch region; other site 272560013621 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 157.4, E-value 1.6e-44 272560013622 PS00211 ABC transporters family signature. 272560013623 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013624 phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701 272560013625 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560013626 Walker A/P-loop; other site 272560013627 ATP binding site [chemical binding]; other site 272560013628 Q-loop/lid; other site 272560013629 ABC transporter signature motif; other site 272560013630 Walker B; other site 272560013631 D-loop; other site 272560013632 H-loop/switch region; other site 272560013633 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560013634 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 172.6, E-value 4.1e-49 272560013635 PS00211 ABC transporters family signature. 272560013636 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013637 Phosphonate metabolizm protein PhnJ; Region: PhnJ; pfam06007 272560013638 Bacterial phosphonate metabolizm protein (PhnI); Region: PhnI; pfam05861 272560013639 carbon-phosphorus lyase complex subunit; Validated; Region: phnH; PRK10147 272560013640 Phosphonate metabolizm protein PhnG; Region: PhnG; pfam06754 272560013641 phosphonates metabolism transcriptional regulator PhnF; Region: C_P_lyase_phnF; TIGR02325 272560013642 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560013643 DNA-binding site [nucleotide binding]; DNA binding site 272560013644 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 272560013645 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 73.5, E-value 2.8e-19 272560013646 PS00043 Bacterial regulatory proteins, gntR family signature. 272560013647 putative phosphonate metabolism protein; Region: Phn_opern_protn; TIGR03223 272560013648 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 272560013649 active site 272560013650 4-Hydroxybenzoate polyprenyltransferase; Region: PT_UbiA_COQ2; cd13959 272560013651 putative active site [active] 272560013652 6 probable transmembrane helices predicted for BPSL2861 by TMHMM2.0 at aa 120-142, 162-184, 188-207, 236-258, 263-280 and 293-315 272560013653 Pfam match to entry PF01040 UbiA, UbiA prenyltransferase , score 215.3, E-value 6e-62 272560013654 PS00943 UbiA prenyltransferase signature. 272560013655 Predicted transcriptional regulators [Transcription]; Region: COG1733 272560013656 Pfam match to entry PF01638 DUF24, Transcriptional regulator , score 102.8, E-value 4.5e-28 272560013657 DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043 272560013658 Ferritin-like domain; Region: Ferritin; pfam00210 272560013659 dimerization interface [polypeptide binding]; other site 272560013660 DPS ferroxidase diiron center [ion binding]; other site 272560013661 ion pore; other site 272560013662 Pfam match to entry PF00210 ferritin, Ferritin-like domain , score 122.7, E-value 4.4e-34 272560013663 PS00819 Dps protein family signature 2. 272560013664 PS00818 Dps protein family signature 1. 272560013665 catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061 272560013666 N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649 272560013667 dimer interface [polypeptide binding]; other site 272560013668 active site 272560013669 heme binding site [chemical binding]; other site 272560013670 C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200 272560013671 Pfam match to entry PF00141 peroxidase, Peroxidase , score 322.1, E-value 4.3e-94 272560013672 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013673 PS00435 Peroxidases proximal heme-ligand signature. 272560013674 PS00436 Peroxidases active site signature. 272560013675 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560013676 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560013677 The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411 272560013678 dimerization interface [polypeptide binding]; other site 272560013679 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 171.6, E-value 8.7e-49 272560013680 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 85.4, E-value 7.6e-23 272560013681 PS00044 Bacterial regulatory proteins, lysR family signature. 272560013682 ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917 272560013683 RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488 272560013684 generic binding surface II; other site 272560013685 ssDNA binding site; other site 272560013686 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560013687 ATP binding site [chemical binding]; other site 272560013688 putative Mg++ binding site [ion binding]; other site 272560013689 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560013690 nucleotide binding region [chemical binding]; other site 272560013691 ATP-binding site [chemical binding]; other site 272560013692 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 72.7, E-value 5.1e-19 272560013693 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 112.1, E-value 7.1e-31 272560013694 PS00435 Peroxidases proximal heme-ligand signature. 272560013695 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013696 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147 272560013697 Pfam match to entry PF02547 Queuosine_synth, Queuosine biosynthesis protein , score 253.5, E-value 1.9e-73 272560013698 queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112 272560013699 Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343 272560013700 Pfam match to entry PF01702 TGT, Queuine tRNA-ribosyltransferase , score 443.0, E-value 1.7e-130 272560013701 preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585 272560013702 Pfam match to entry PF02699 DUF219, Uncharacterized secreted proteins, YajC family COG1862 , score 131.6, E-value 9.6e-37 272560013703 1 probable transmembrane helix predicted for BPSL2870 by TMHMM2.0 at aa 20-38 272560013704 SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721 272560013705 Signal peptide predicted for BPSL2871 by SignalP 2.0 HMM (Signal peptide probabilty 0.728) with cleavage site probability 0.219 between residues 33 and 34; signal peptide 272560013706 preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812 272560013707 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 272560013708 protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916 272560013709 Uncharacterized conserved protein [Function unknown]; Region: COG1615; cl09133 272560013710 Pfam match to entry PF02355 SecD_SecF, Protein export membrane protein , score -37.8, E-value 3.6e-07 272560013711 5 probable transmembrane helices predicted for BPSL2871 by TMHMM2.0 at aa 447-469, 471-493, 497-519, 540-562 and 572-594 272560013712 preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022 272560013713 SecD/SecF GG Motif; Region: Sec_GG; pfam07549 272560013714 Protein export membrane protein; Region: SecD_SecF; pfam02355 272560013715 6 probable transmembrane helices predicted for BPSL2872 by TMHMM2.0 at aa 17-39, 133-155, 160-182, 186-208, 248-266 and 270-292 272560013716 Pfam match to entry PF02355 SecD_SecF, Protein export membrane protein , score 327.5, E-value 9.6e-96 272560013717 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560013718 6 probable transmembrane helices predicted for BPSL2873 by TMHMM2.0 at aa 19-41, 56-78, 90-112, 116-138, 151-173 and 183-200 272560013719 Signal peptide predicted for BPSL2874 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 22 and 23; signal peptide 272560013720 Uncharacterized conserved protein [Function unknown]; Region: COG2353 272560013721 Signal peptide predicted for BPSL2875 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.997 between residues 26 and 27; signal peptide 272560013722 YceI-like domain; Region: YceI; smart00867 272560013723 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 272560013724 3 probable transmembrane helices predicted for BPSL2876 by TMHMM2.0 at aa 23-45, 65-87 and 121-138 272560013725 Paraquat-inducible protein A; Region: PqiA; pfam04403 272560013726 4 probable transmembrane helices predicted for BPSL2877 by TMHMM2.0 at aa 47-66, 96-118, 139-161 and 166-188 272560013727 Paraquat-inducible protein A; Region: PqiA; pfam04403 272560013728 4 probable transmembrane helices predicted for BPSL2878 by TMHMM2.0 at aa 56-78, 111-133, 154-173 and 177-199 272560013729 Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008 272560013730 mce related protein; Region: MCE; pfam02470 272560013731 mce related protein; Region: MCE; pfam02470 272560013732 mce related protein; Region: MCE; pfam02470 272560013733 The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013 272560013734 1 probable transmembrane helix predicted for BPSL2879 by TMHMM2.0 at aa 38-60 272560013735 Signal peptide predicted for BPSL2880 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.260 between residues 49 and 50; signal peptide 272560013736 Protein of unknown function (DUF330); Region: DUF330; pfam03886 272560013737 Pfam match to entry PF03886 DUF330, Protein of unknown function (DUF330) , score 27.5, E-value 1.8e-07 272560013738 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013739 Site-specific recombinase; Region: SpecificRecomb; pfam10136 272560013740 6 probable transmembrane helices predicted for BPSL2881 by TMHMM2.0 at aa 376-398, 408-430, 472-494, 514-536, 580-602 and 634-656 272560013741 Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116 272560013742 THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715 272560013743 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560013744 Pfam match to entry PF02926 THUMP, THUMP domain , score 44.2, E-value 1.9e-10 272560013745 Pfam match to entry PF01170 UPF0020, RNA methylase UPF0020 , score 196.0, E-value 3.9e-56 272560013746 PS00092 N-6 Adenine-specific DNA methylases signature. 272560013747 N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247 272560013748 Predicted transcriptional regulator [Transcription]; Region: COG2378 272560013749 HTH domain; Region: HTH_11; pfam08279 272560013750 WYL domain; Region: WYL; pfam13280 272560013751 NAD/NADP transhydrogenase beta subunit [Energy production and conversion]; Region: PntB; COG1282 272560013752 Pfam match to entry PF02233 PNTB, NAD(P) transhydrogenase beta subunit , score 879.0, E-value 9.6e-262 272560013753 8 probable transmembrane helices predicted for BPSL2885 by TMHMM2.0 at aa 4-21, 34-53, 63-85, 97-116, 143-165, 185-204, 209-231 and 252-274 272560013754 Domain of unknown function (DUF3814); Region: DUF3814; pfam12769 272560013755 3 probable transmembrane helices predicted for BPSL2886 by TMHMM2.0 at aa 4-26, 38-60 and 65-84 272560013756 Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304 272560013757 NAD/NADP transhydrogenase alpha subunit [Energy production and conversion]; Region: PntA; COG3288 272560013758 ligand binding site [chemical binding]; other site 272560013759 homodimer interface [polypeptide binding]; other site 272560013760 NAD(P) binding site [chemical binding]; other site 272560013761 trimer interface B [polypeptide binding]; other site 272560013762 trimer interface A [polypeptide binding]; other site 272560013763 Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase , score 112.4, E-value 5.6e-31 272560013764 Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675 272560013765 nudix motif; other site 272560013766 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 64.4, E-value 1.5e-16 272560013767 PS00893 mutT domain signature. 272560013768 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482 272560013769 tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998 272560013770 Ligand Binding Site [chemical binding]; other site 272560013771 Pfam match to entry PF03054 tRNA_Me_trans, tRNA methyl transferase , score 665.9, E-value 1.4e-197 272560013772 Glutamate synthase domain 2 [Amino acid transport and metabolism]; Region: GltB; COG0069 272560013773 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 272560013774 active site 272560013775 FMN binding site [chemical binding]; other site 272560013776 substrate binding site [chemical binding]; other site 272560013777 3Fe-4S cluster binding site [ion binding]; other site 272560013778 3 probable transmembrane helices predicted for BPSL2890 by TMHMM2.0 at aa 28-45, 50-69 and 174-196 272560013779 Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase , score 281.3, E-value 8.2e-82 272560013780 PS00881 Protein splicing signature. 272560013781 putative glutathione S-transferase; Provisional; Region: PRK10357 272560013782 GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049 272560013783 putative C-terminal domain interface [polypeptide binding]; other site 272560013784 putative GSH binding site (G-site) [chemical binding]; other site 272560013785 putative dimer interface [polypeptide binding]; other site 272560013786 C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205 272560013787 dimer interface [polypeptide binding]; other site 272560013788 N-terminal domain interface [polypeptide binding]; other site 272560013789 putative substrate binding pocket (H-site) [chemical binding]; other site 272560013790 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 27.7, E-value 1.7e-05 272560013791 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 37.2, E-value 2.4e-08 272560013792 Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195 272560013793 proline aminopeptidase P II; Provisional; Region: PRK10879 272560013794 Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087 272560013795 active site 272560013796 Pfam match to entry PF00557 Peptidase_M24, metallopeptidase M24 , score 259.0, E-value 4e-75 272560013797 PS00491 Aminopeptidase P and proline dipeptidase signature. 272560013798 hypothetical protein; Provisional; Region: PRK06996 272560013799 2-polyprenyl-6-methoxyphenol 4-hydroxylase; Region: UbiH; TIGR01984 272560013800 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 55.2, E-value 9.4e-14 272560013801 PS01304 ubiH/COQ6 monooxygenase signature. 272560013802 tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415 272560013803 Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801 272560013804 FMN binding site [chemical binding]; other site 272560013805 active site 272560013806 catalytic residues [active] 272560013807 substrate binding site [chemical binding]; other site 272560013808 Pfam match to entry PF01207 UPF0034, Uncharacterized protein family UPF0034 , score 421.8, E-value 4e-124 272560013809 PS01136 Uncharacterized protein family UPF0034 signature. 272560013810 DNA-binding protein Fis; Provisional; Region: PRK01905 272560013811 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 59.0, E-value 6.8e-15 272560013812 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881 272560013813 Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal ATIC formylase domain that formylates...; Region: IMPCH; cd01421 272560013814 purine monophosphate binding site [chemical binding]; other site 272560013815 dimer interface [polypeptide binding]; other site 272560013816 putative catalytic residues [active] 272560013817 AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798 272560013818 Pfam match to entry PF02142 MGS, MGS-like domain , score 208.0, E-value 9.2e-60 272560013819 Pfam match to entry PF01808 AICARFT_IMPCHas, AICARFT/IMPCHase bienzyme , score 543.9, E-value 7e-161 272560013820 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 272560013821 Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529 272560013822 active site 272560013823 putative DNA-binding cleft [nucleotide binding]; other site 272560013824 dimer interface [polypeptide binding]; other site 272560013825 Pfam match to entry PF02075 RuvC, Crossover junction endodeoxyribonuclease RuvC , score 248.1, E-value 7.9e-72 272560013826 Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116 272560013827 RuvA N terminal domain; Region: RuvA_N; pfam01330 272560013828 Helix-hairpin-helix domain; Region: HHH_5; pfam14520 272560013829 RuvA, C-terminal domain; Region: RuvA_C; pfam07499 272560013830 Pfam match to entry PF01330 RuvA, RuvA N terminal domain , score 106.9, E-value 2.6e-29 272560013831 Pfam match to entry PF02904 RuvA_II, RuvA central domain II , score 117.5, E-value 1.6e-32 272560013832 Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080 272560013833 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560013834 Walker A motif; other site 272560013835 ATP binding site [chemical binding]; other site 272560013836 Walker B motif; other site 272560013837 arginine finger; other site 272560013838 Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491 272560013839 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 113.1, E-value 3.5e-31 272560013840 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013841 Uncharacterized protein conserved in bacteria (DUF2236); Region: DUF2236; cl01472 272560013842 Signal peptide predicted for BPSL2901 by SignalP 2.0 HMM (Signal peptide probabilty 0.990) with cleavage site probability 0.510 between residues 33 and 34; signal peptide 272560013843 Putative ParB-like nuclease; Region: ParBc_2; cl17538 272560013844 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560013845 Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067 272560013846 catalytic core [active] 272560013847 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score 157.3, E-value 1.7e-44 272560013848 D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563 272560013849 putative active site [active] 272560013850 dimerization interface [polypeptide binding]; other site 272560013851 putative tRNAtyr binding site [nucleotide binding]; other site 272560013852 Pfam match to entry PF02580 DUF154, Uncharacterized ACR, COG1490 , score 182.0, E-value 6.1e-52 272560013853 tyrosyl-tRNA synthetase; Validated; Region: PRK05912 272560013854 catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805 272560013855 active site 272560013856 HIGH motif; other site 272560013857 dimer interface [polypeptide binding]; other site 272560013858 KMSKS motif; other site 272560013859 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560013860 RNA binding surface [nucleotide binding]; other site 272560013861 Pfam match to entry PF01479 S4, S4 domain , score 25.4, E-value 8.5e-05 272560013862 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y) , score 338.5, E-value 4.8e-99 272560013863 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560013864 anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585 272560013865 Pfam match to entry PF03702 UPF0075, Uncharacterised protein family (UPF0075) , score 523.1, E-value 1.4e-154 272560013866 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 272560013867 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 272560013868 C-terminal domain interface [polypeptide binding]; other site 272560013869 GSH binding site (G-site) [chemical binding]; other site 272560013870 dimer interface [polypeptide binding]; other site 272560013871 C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291 272560013872 N-terminal domain interface [polypeptide binding]; other site 272560013873 putative dimer interface [polypeptide binding]; other site 272560013874 active site 272560013875 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 46.2, E-value 4.7e-11 272560013876 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 62.5, E-value 5.8e-16 272560013877 GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972 272560013878 GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048 272560013879 C-terminal domain interface [polypeptide binding]; other site 272560013880 GSH binding site (G-site) [chemical binding]; other site 272560013881 dimer interface [polypeptide binding]; other site 272560013882 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 272560013883 N-terminal domain interface [polypeptide binding]; other site 272560013884 dimer interface [polypeptide binding]; other site 272560013885 substrate binding pocket (H-site) [chemical binding]; other site 272560013886 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 28.5, E-value 1e-05 272560013887 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 68.3, E-value 1e-17 272560013888 Cupin; Region: Cupin_6; pfam12852 272560013889 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560013890 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560013891 PS00041 Bacterial regulatory proteins, araC family signature. 272560013892 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 22.7, E-value 0.00056 272560013893 PS00041 Bacterial regulatory proteins, araC family signature. 272560013894 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 28.6, E-value 9.7e-06 272560013895 iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623 272560013896 Pfam match to entry PF01521 HesB-like, HesB-like domain , score 181.9, E-value 6.6e-52 272560013897 PS01152 Hypothetical hesB/yadR/yfhF family signature. 272560013898 30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132 272560013899 Pfam match to entry PF00380 Ribosomal_S9, Ribosomal protein S9/S16 , score 199.6, E-value 3.1e-57 272560013900 PS00360 Ribosomal protein S9 signature. 272560013901 Ribosomal protein L13. Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392 272560013902 23S rRNA interface [nucleotide binding]; other site 272560013903 L3 interface [polypeptide binding]; other site 272560013904 Pfam match to entry PF00572 Ribosomal_L13, Ribosomal protein L13 , score 252.3, E-value 4.4e-73 272560013905 OsmC-like protein; Region: OsmC; cl00767 272560013906 Pfam match to entry PF02566 OsmC, OsmC-like protein , score 142.0, E-value 6.8e-40 272560013907 Protein of unknown function (DUF3025); Region: DUF3025; pfam11227 272560013908 Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294 272560013909 active site 272560013910 substrate binding pocket [chemical binding]; other site 272560013911 dimer interface [polypeptide binding]; other site 272560013912 PS00483 Dihydroorotase signature 2. 272560013913 PS00482 Dihydroorotase signature 1. 272560013914 Glutamine amidotransferases class-II (Gn-AT)_YafJ-type. YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea. YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908 272560013915 putative active site [active] 272560013916 Glutamine amidotransferases class-II; Region: GATase_2; pfam00310 272560013917 putative dimer interface [polypeptide binding]; other site 272560013918 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 272560013919 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 272560013920 putative dimer interface [polypeptide binding]; other site 272560013921 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family , score 57.1, E-value 2.5e-14 272560013922 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 272560013923 Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464 272560013924 putative dimer interface [polypeptide binding]; other site 272560013925 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family , score 87.4, E-value 1.9e-23 272560013926 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 272560013927 oligomerisation interface [polypeptide binding]; other site 272560013928 mobile loop; other site 272560013929 roof hairpin; other site 272560013930 Pfam match to entry PF00166 cpn10, Chaperonin 10 Kd subunit , score 191.0, E-value 1.3e-54 272560013931 PS00681 Chaperonins cpn10 signature. 272560013932 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 272560013933 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560013934 Walker A/P-loop; other site 272560013935 ATP binding site [chemical binding]; other site 272560013936 Q-loop/lid; other site 272560013937 ABC transporter signature motif; other site 272560013938 Walker B; other site 272560013939 D-loop; other site 272560013940 H-loop/switch region; other site 272560013941 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 222.0, E-value 5.8e-64 272560013942 PS00211 ABC transporters family signature. 272560013943 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 13.0, E-value 0.0025 272560013944 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013945 ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765 272560013946 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560013947 dimer interface [polypeptide binding]; other site 272560013948 conserved gate region; other site 272560013949 putative PBP binding loops; other site 272560013950 ABC-ATPase subunit interface; other site 272560013951 5 probable transmembrane helices predicted for BPSL2922 by TMHMM2.0 at aa 15-37, 58-80, 95-112, 155-177 and 197-219 272560013952 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 79.5, E-value 4.6e-21 272560013953 ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765 272560013954 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560013955 dimer interface [polypeptide binding]; other site 272560013956 conserved gate region; other site 272560013957 putative PBP binding loops; other site 272560013958 ABC-ATPase subunit interface; other site 272560013959 4 probable transmembrane helices predicted for BPSL2923 by TMHMM2.0 at aa 32-54, 67-89, 104-126 and 211-233 272560013960 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 73.1, E-value 3.7e-19 272560013961 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560013962 Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062 272560013963 substrate binding pocket [chemical binding]; other site 272560013964 membrane-bound complex binding site; other site 272560013965 hinge residues; other site 272560013966 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 190.7, E-value 1.5e-54 272560013967 Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334 272560013968 Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812 272560013969 NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076 272560013970 NAD(P) binding site [chemical binding]; other site 272560013971 Pfam match to entry PF00208 GLFV_dehydrog, Glutamate/Leucine/Phenylalanine/Valine dehydrogenase , score 331.3, E-value 7e-97 272560013972 Pfam match to entry PF02812 GLFV_dehydrog_N, Glu/Leu/Phe/Val dehydrogenase, dimerisation domain , score 222.9, E-value 3e-64 272560013973 PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 272560013974 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560013975 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560013976 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560013977 dimerization interface [polypeptide binding]; other site 272560013978 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 53.6, E-value 2.8e-13 272560013979 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 70.0, E-value 3.2e-18 272560013980 PS00044 Bacterial regulatory proteins, lysR family signature. 272560013981 Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223 272560013982 lysophospholipid transporter LplT; Provisional; Region: PRK11195; cl19150 272560013983 14 probable transmembrane helices predicted for BPSL2927 by TMHMM2.0 at aa 32-54, 64-86, 98-117, 122-144, 157-179, 189-208, 221-243, 248-267, 279-301, 316-333, 340-362, 366-388, 401-423 and 433-452 272560013984 adenylosuccinate lyase; Provisional; Region: PRK09285 272560013985 PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598 272560013986 tetramer interface [polypeptide binding]; other site 272560013987 active site 272560013988 Pfam match to entry PF00206 lyase_1, Lyase , score 289.4, E-value 3e-84 272560013989 PS00163 Fumarate lyases signature. 272560013990 Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021 272560013991 AAA domain; Region: AAA_33; pfam13671 272560013992 ATP-binding site [chemical binding]; other site 272560013993 Gluconate-6-phosphate binding site [chemical binding]; other site 272560013994 PS00017 ATP/GTP-binding site motif A (P-loop). 272560013995 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 272560013996 GntP family permease; Region: GntP_permease; pfam02447 272560013997 12 probable transmembrane helices predicted for BPSL2930 by TMHMM2.0 at aa 7-25, 29-46, 59-78, 107-129, 142-161, 181-203, 232-254, 277-296, 309-328, 338-360, 367-389 and 430-452 272560013998 Pfam match to entry PF02447 GntP_permease, GntP family permease , score 729.2, E-value 1.2e-216 272560013999 Entner-Doudoroff aldolase; Region: eda; TIGR01182 272560014000 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 272560014001 active site 272560014002 intersubunit interface [polypeptide binding]; other site 272560014003 catalytic residue [active] 272560014004 Pfam match to entry PF01081 Aldolase, KDPG and KHG aldolase , score 264.3, E-value 1e-76 272560014005 PS00160 KDPG and KHG aldolases Schiff-base forming residue. 272560014006 PS00159 KDPG and KHG aldolases active site. 272560014007 phosphogluconate dehydratase; Validated; Region: PRK09054 272560014008 Pfam match to entry PF00920 ILVD_EDD, Dehydratase , score 907.9, E-value 1.9e-270 272560014009 PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 272560014010 PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 272560014011 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 104.2, E-value 1.6e-28 272560014012 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560014013 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560014014 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560014015 putative active site [active] 272560014016 Pfam match to entry PF01380 SIS, SIS domain , score 97.7, E-value 1.5e-26 272560014017 Uncharacterized protein family (UPF0093); Region: UPF0093; cl00863 272560014018 Pfam match to entry PF03653 UPF0093, Uncharacterised protein family (UPF0093) , score 127.5, E-value 1.6e-35 272560014019 4 probable transmembrane helices predicted for BPSL2934 by TMHMM2.0 at aa 15-37, 57-79, 94-112 and 125-144 272560014020 Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079 272560014021 putative catalytic cysteine [active] 272560014022 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score -194.5, E-value 6.6e-07 272560014023 PS01223 Gamma-glutamyl phosphate reductase signature. 272560014024 DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574 272560014025 DNA polymerase III, delta subunit; Region: DNA_pol3_delta; cl19912 272560014026 Processivity clamp loader gamma complex DNA pol III C-term; Region: DNA_pol3_delt_C; pfam14840 272560014027 Lipopolysaccharide-assembly; Region: LptE; cl01125 272560014028 PS00237 G-protein coupled receptors signature. 272560014029 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560014030 1 probable transmembrane helix predicted for BPSL2937 by TMHMM2.0 at aa 21-40 272560014031 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014032 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 272560014033 catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812 272560014034 active site 272560014035 HIGH motif; other site 272560014036 KMSKS motif; other site 272560014037 Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958 272560014038 tRNA binding surface [nucleotide binding]; other site 272560014039 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 272560014040 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score 500.3, E-value 9.8e-148 272560014041 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560014042 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 272560014043 Pfam match to entry PF02472 ExbD, Biopolymer transport protein ExbD/TolR , score 71.6, E-value 1e-18 272560014044 1 probable transmembrane helix predicted for BPSL2939 by TMHMM2.0 at aa 43-65 272560014045 Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811 272560014046 Pfam match to entry PF01618 MotA_ExbB, MotA/TolQ/ExbB proton channel family , score 154.8, E-value 9.5e-44 272560014047 3 probable transmembrane helices predicted for BPSL2940 by TMHMM2.0 at aa 20-42, 130-152 and 176-198 272560014048 dihydrodipicolinate reductase; Provisional; Region: PRK00048 272560014049 Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113 272560014050 Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173 272560014051 Pfam match to entry PF01113 DapB, Dihydrodipicolinate reductase , score 287.9, E-value 8.4e-84 272560014052 PS01298 Dihydrodipicolinate reductase signature. 272560014053 Signal peptide predicted for BPSL2942 by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.462 between residues 41 and 42; signal peptide 272560014054 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 272560014055 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014056 Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153 272560014057 metal binding site 2 [ion binding]; metal-binding site 272560014058 putative DNA binding helix; other site 272560014059 metal binding site 1 [ion binding]; metal-binding site 272560014060 dimer interface [polypeptide binding]; other site 272560014061 structural Zn2+ binding site [ion binding]; other site 272560014062 Pfam match to entry PF01475 FUR, Ferric uptake regulator family , score 234.0, E-value 1.4e-67 272560014063 ureidoglycolate hydrolase; Provisional; Region: PRK13395 272560014064 allantoicase; Provisional; Region: PRK13257 272560014065 Allantoicase repeat; Region: Allantoicase; pfam03561 272560014066 Allantoicase repeat; Region: Allantoicase; pfam03561 272560014067 Pfam match to entry PF03561 Allantoicase, Allantoicase repeat , score 245.5, E-value 4.7e-71 272560014068 Pfam match to entry PF03561 Allantoicase, Allantoicase repeat , score 243.8, E-value 1.6e-70 272560014069 C4-dicarboxylate transporter DctA; Reviewed; Region: PRK13027 272560014070 Signal peptide predicted for BPSL2946 by SignalP 2.0 HMM (Signal peptide probabilty 0.994) with cleavage site probability 0.711 between residues 32 and 33; signal peptide 272560014071 8 probable transmembrane helices predicted for BPSL2946 by TMHMM2.0 at aa 7-29, 44-63, 76-98, 150-167, 184-206, 219-241, 351-373 and 379-401 272560014072 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 470.7, E-value 7.6e-139 272560014073 PS00713 Sodium:dicarboxylate symporter family signature 1. 272560014074 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560014075 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560014076 DNA-binding site [nucleotide binding]; DNA binding site 272560014077 FCD domain; Region: FCD; pfam07729 272560014078 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 79.0, E-value 6.3e-21 272560014079 PS00043 Bacterial regulatory proteins, gntR family signature. 272560014080 DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242 272560014081 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560014082 The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425 272560014083 dimerization interface [polypeptide binding]; other site 272560014084 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 191.4, E-value 9.3e-55 272560014085 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 114.7, E-value 1.1e-31 272560014086 PS00044 Bacterial regulatory proteins, lysR family signature. 272560014087 Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884 272560014088 active site clefts [active] 272560014089 zinc binding site [ion binding]; other site 272560014090 dimer interface [polypeptide binding]; other site 272560014091 Pfam match to entry PF00484 Pro_CA, Carbonic anhydrase , score 347.8, E-value 7.7e-102 272560014092 PS00704 Prokaryotic-type carbonic anhydrases signature 1. 272560014093 PS00705 Prokaryotic-type carbonic anhydrases signature 2. 272560014094 cyanate hydratase; Validated; Region: PRK02866 272560014095 Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate. It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559 272560014096 oligomer interface [polypeptide binding]; other site 272560014097 active site 272560014098 Pfam match to entry PF02560 Cyanate_lyase, Cyanate lyase C-terminal domain , score 170.4, E-value 1.9e-48 272560014099 Signal peptide predicted for BPSL2951 by SignalP 2.0 HMM (Signal peptide probabilty 0.881) with cleavage site probability 0.804 between residues 38 and 39; signal peptide 272560014100 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560014101 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560014102 12 probable transmembrane helices predicted for BPSL2951 by TMHMM2.0 at aa 9-31, 51-73, 80-99, 104-126, 138-160, 164-186, 215-237, 252-274, 281-300, 304-323, 343-365 and 370-389 272560014103 PS00211 ABC transporters family signature. 272560014104 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057 272560014105 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846 272560014106 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800 272560014107 Pfam match to entry PF02800 gpdh_C, Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain , score 338.5, E-value 4.8e-99 272560014108 PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 272560014109 Pfam match to entry PF00044 gpdh, Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain , score 326.8, E-value 1.6e-95 272560014110 transketolase; Reviewed; Region: PRK12753 272560014111 Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012 272560014112 TPP-binding site [chemical binding]; other site 272560014113 dimer interface [polypeptide binding]; other site 272560014114 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 272560014115 PYR/PP interface [polypeptide binding]; other site 272560014116 dimer interface [polypeptide binding]; other site 272560014117 TPP binding site [chemical binding]; other site 272560014118 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 272560014119 Pfam match to entry PF02780 transketolase_C, Transketolase, C-terminal domain , score 50.1, E-value 3.1e-12 272560014120 Pfam match to entry PF02779 transket_pyr, Transketolase, pyridine binding domain , score 206.7, E-value 2.3e-59 272560014121 Pfam match to entry PF00456 transketolase, Transketolase, thiamine diphosphate binding domain , score 777.5, E-value 3.4e-231 272560014122 PS00801 Transketolase signature 1. 272560014123 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560014124 S-adenosylmethionine binding site [chemical binding]; other site 272560014125 Pfam match to entry PF01564 Spermine_synth, Spermine/spermidine synthase , score 181.4, E-value 9.4e-52 272560014126 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246 272560014127 putative dimer interface [polypeptide binding]; other site 272560014128 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 36.6, E-value 3.7e-08 272560014129 16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713 272560014130 Barstar (barnase inhibitor); Region: Barstar; pfam01337 272560014131 RNAase interaction site [polypeptide binding]; other site 272560014132 Pfam match to entry PF01337 Barstar, Barstar (barnase inhibitor) , score 1.6, E-value 0.002 272560014133 Signal peptide predicted for BPSL2958 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.657 between residues 36 and 37; signal peptide 272560014134 RNase_Sa. Ribonucleases first isolated from Streptomyces aureofaciens. In general, ribonucleases cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing. RNAse Sa is a guanylate...; Region: RNase_Sa; cd00607 272560014135 active site 272560014136 barstar interaction site; other site 272560014137 Pfam match to entry PF00545 ribonuclease, ribonuclease , score 55.0, E-value 1.1e-13 272560014138 1 probable transmembrane helix predicted for BPSL2958 by TMHMM2.0 at aa 10-32 272560014139 malic enzyme; Reviewed; Region: PRK12862 272560014140 Malic enzyme, N-terminal domain; Region: malic; pfam00390 272560014141 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 272560014142 putative NAD(P) binding site [chemical binding]; other site 272560014143 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 272560014144 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase , score 397.8, E-value 6.7e-117 272560014145 Pfam match to entry PF03949 malic_N, Malic enzyme, NAD binding domain , score 398.2, E-value 5.2e-117 272560014146 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014147 Pfam match to entry PF00390 malic, Malic enzyme, N-terminal domain , score 240.8, E-value 1.3e-69 272560014148 thiamine monophosphate kinase; Provisional; Region: PRK05731 272560014149 ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194 272560014150 ATP binding site [chemical binding]; other site 272560014151 dimerization interface [polypeptide binding]; other site 272560014152 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain , score 16.3, E-value 0.0002 272560014153 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain , score 14.3, E-value 0.00027 272560014154 Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971 272560014155 tetramer interfaces [polypeptide binding]; other site 272560014156 binuclear metal-binding site [ion binding]; other site 272560014157 4 probable transmembrane helices predicted for BPSL2961 by TMHMM2.0 at aa 15-37, 49-66, 86-108 and 129-151 272560014158 Competence-damaged protein; Region: CinA; pfam02464 272560014159 Pfam match to entry PF02464 CinA, Competence-damaged protein , score 250.6, E-value 1.4e-72 272560014160 Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725 272560014161 active site 272560014162 dimer interface [polypeptide binding]; other site 272560014163 Pfam match to entry PF00215 OMPdecase, Orotidine 5'-phosphate decarboxylase / HUMPS family , score 114.6, E-value 1.2e-31 272560014164 PS00156 Orotidine 5'-phosphate decarboxylase active site. 272560014165 aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021 272560014166 active site 272560014167 catalytic residues [active] 272560014168 Pfam match to entry PF01263 Aldose_epim, Aldose 1-epimerase , score 102.7, E-value 4.8e-28 272560014169 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560014170 classical (c) SDRs; Region: SDR_c; cd05233 272560014171 NAD(P) binding site [chemical binding]; other site 272560014172 active site 272560014173 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 185.9, E-value 4.3e-53 272560014174 PS00061 Short-chain dehydrogenases/reductases family signature. 272560014175 1 probable transmembrane helix predicted for BPSL2965 by TMHMM2.0 at aa 21-43 272560014176 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560014177 TM-ABC transporter signature motif; other site 272560014178 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -23.5, E-value 1.3e-05 272560014179 8 probable transmembrane helices predicted for BPSL2966 by TMHMM2.0 at aa 47-64, 74-96, 101-120, 124-146, 151-170, 190-212, 244-266 and 298-320 272560014180 L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288 272560014181 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560014182 Walker A/P-loop; other site 272560014183 ATP binding site [chemical binding]; other site 272560014184 Q-loop/lid; other site 272560014185 ABC transporter signature motif; other site 272560014186 Walker B; other site 272560014187 D-loop; other site 272560014188 H-loop/switch region; other site 272560014189 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560014190 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 95.7, E-value 5.8e-26 272560014191 PS00211 ABC transporters family signature. 272560014192 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 185.3, E-value 6.4e-53 272560014193 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014194 Signal peptide predicted for BPSL2968 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 24 and 25; signal peptide 272560014195 Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540 272560014196 Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532 272560014197 ligand binding site [chemical binding]; other site 272560014198 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 112.0, E-value 7.5e-31 272560014199 short chain dehydrogenase; Provisional; Region: PRK07063 272560014200 classical (c) SDRs; Region: SDR_c; cd05233 272560014201 NAD(P) binding site [chemical binding]; other site 272560014202 active site 272560014203 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 277.7, E-value 1e-80 272560014204 PS00061 Short-chain dehydrogenases/reductases family signature. 272560014205 KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452 272560014206 active site 272560014207 intersubunit interface [polypeptide binding]; other site 272560014208 catalytic residue [active] 272560014209 Pfam match to entry PF01081 Aldolase, KDPG and KHG aldolase , score 32.5, E-value 1.2e-11 272560014210 2-keto-3-deoxy-galactonokinase; Region: DGOK; pfam05035 272560014211 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560014212 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560014213 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560014214 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 144.1, E-value 1.6e-40 272560014215 Signal peptide predicted for BPSL2973 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 36 and 37; signal peptide 272560014216 PS00018 EF-hand calcium-binding domain. 272560014217 Signal peptide predicted for BPSL2974 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.416 between residues 33 and 34; signal peptide 272560014218 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 272560014219 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 272560014220 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014221 Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744 272560014222 monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056 272560014223 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 175.8, E-value 4.6e-50 272560014224 1 probable transmembrane helix predicted for BPSL2975 by TMHMM2.0 at aa 26-48 272560014225 shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258 272560014226 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 272560014227 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 272560014228 shikimate binding site; other site 272560014229 NAD(P) binding site [chemical binding]; other site 272560014230 Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase , score 298.8, E-value 4.2e-87 272560014231 Exoribonuclease R [Transcription]; Region: VacB; COG0557 272560014232 RNB domain; Region: RNB; pfam00773 272560014233 Pfam match to entry PF00773 RNB, RNB-like protein , score -12.9, E-value 6.2e-09 272560014234 Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886 272560014235 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560014236 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081 272560014237 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 272560014238 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560014239 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560014240 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 59.6, E-value 4.3e-15 272560014241 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 187.1, E-value 1.9e-53 272560014242 1 probable transmembrane helix predicted for BPSL2979 by TMHMM2.0 at aa 27-49 272560014243 TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966 272560014244 catalytic residues [active] 272560014245 Pfam match to entry PF00085 thiored, Thioredoxin , score 16.2, E-value 9.8e-05 272560014246 PS00194 Thioredoxin family active site. 272560014247 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 272560014248 trimer interface [polypeptide binding]; other site 272560014249 active site 272560014250 dimer interface [polypeptide binding]; other site 272560014251 Pfam match to entry PF01220 DHquinase_II, Dehydroquinase class II , score 305.6, E-value 3.9e-89 272560014252 acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302 272560014253 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 272560014254 carboxyltransferase (CT) interaction site; other site 272560014255 biotinylation site [posttranslational modification]; other site 272560014256 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 138.1, E-value 1.1e-38 272560014257 PS00188 Biotin-requiring enzymes attachment site. 272560014258 acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591 272560014259 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560014260 Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786 272560014261 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 272560014262 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 188.4, E-value 7.2e-54 272560014263 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 383.0, E-value 2e-112 272560014264 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560014265 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560014266 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain , score 213.0, E-value 3e-61 272560014267 ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517 272560014268 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560014269 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560014270 S-adenosylmethionine binding site [chemical binding]; other site 272560014271 MJ0042 family finger-like domain; Region: MJ0042_CXXC; TIGR02098 272560014272 Protein of unknown function (DUF3426); Region: DUF3426; pfam11906 272560014273 1 probable transmembrane helix predicted for BPSL2986 by TMHMM2.0 at aa 314-336 272560014274 Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014 272560014275 dimer interface [polypeptide binding]; other site 272560014276 catalytic triad [active] 272560014277 peroxidatic and resolving cysteines [active] 272560014278 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 112.4, E-value 5.7e-31 272560014279 PS01265 Tpx family signature. 272560014280 PS00659 Glycosyl hydrolases family 5 signature. 272560014281 Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time; Region: ribokinase_group_A; cd01942 272560014282 substrate binding site [chemical binding]; other site 272560014283 ATP binding site [chemical binding]; other site 272560014284 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 131.8, E-value 8e-37 272560014285 PS00583 pfkB family of carbohydrate kinases signature 1. 272560014286 Signal peptide predicted for BPSL2989 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.933 between residues 29 and 30; signal peptide 272560014287 Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470 272560014288 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014289 Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049 272560014290 dimer interface [polypeptide binding]; other site 272560014291 putative radical transfer pathway; other site 272560014292 diiron center [ion binding]; other site 272560014293 tyrosyl radical; other site 272560014294 Pfam match to entry PF00268 ribonuc_red_sm, Ribonucleotide reductase, small chain , score 150.5, E-value 1.9e-42 272560014295 1 probable transmembrane helix predicted for BPSL2991 by TMHMM2.0 at aa 213-235 272560014296 ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07207 272560014297 ATP cone domain; Region: ATP-cone; pfam03477 272560014298 Class I ribonucleotide reductase; Region: RNR_I; cd01679 272560014299 active site 272560014300 dimer interface [polypeptide binding]; other site 272560014301 catalytic residues [active] 272560014302 effector binding site; other site 272560014303 R2 peptide binding site; other site 272560014304 Pfam match to entry PF02867 ribonuc_red_lgC, Ribonucleotide reductase, barrel domain , score 602.0, E-value 2.3e-178 272560014305 PS00089 Ribonucleotide reductase large subunit signature. 272560014306 PS00185 Isopenicillin N synthetase signature 1. 272560014307 Pfam match to entry PF00317 ribonuc_red_lg, Ribonucleotide reductase, all-alpha domain , score 109.3, E-value 4.7e-30 272560014308 Pfam match to entry PF03477 ATP-cone, ATP cone domain , score 78.0, E-value 1.3e-20 272560014309 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 272560014310 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 272560014311 amidase catalytic site [active] 272560014312 Zn binding residues [ion binding]; other site 272560014313 substrate binding site [chemical binding]; other site 272560014314 Pfam match to entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase , score 170.2, E-value 2.3e-48 272560014315 Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191 272560014316 Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504 272560014317 8 probable transmembrane helices predicted for BPSL2994 by TMHMM2.0 at aa 4-21, 52-74, 78-100, 112-134, 144-166, 204-226, 241-258 and 271-290 272560014318 signal recognition particle protein; Provisional; Region: PRK10867 272560014319 SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963 272560014320 The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115 272560014321 P loop; other site 272560014322 GTP binding site [chemical binding]; other site 272560014323 Signal peptide binding domain; Region: SRP_SPB; pfam02978 272560014324 Pfam match to entry PF02881 SRP54_N, SRP54-type protein, helical bundle domain , score 98.6, E-value 7.8e-27 272560014325 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain , score 376.9, E-value 1.3e-110 272560014326 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014327 Pfam match to entry PF02978 SRP_SPB, Signal peptide binding domain , score 148.6, E-value 7.2e-42 272560014328 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560014329 active site 272560014330 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 50.1, E-value 3.2e-12 272560014331 Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095 272560014332 Pfam match to entry PF01914 MarC, MarC family integral membrane protein , score 187.5, E-value 1.4e-53 272560014333 6 probable transmembrane helices predicted for BPSL2997 by TMHMM2.0 at aa 5-27, 40-59, 74-91, 108-130, 140-158 and 171-193 272560014334 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560014335 prolyl-tRNA synthetase; Provisional; Region: PRK09194 272560014336 Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779 272560014337 dimer interface [polypeptide binding]; other site 272560014338 motif 1; other site 272560014339 active site 272560014340 motif 2; other site 272560014341 INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334 272560014342 putative deacylase active site [active] 272560014343 motif 3; other site 272560014344 ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861 272560014345 anticodon binding site; other site 272560014346 Pfam match to entry PF03129 HGTP_anticodon, Anticodon binding domain , score 101.7, E-value 9.6e-28 272560014347 Pfam match to entry PF00587 tRNA-synt_2b, tRNA synthetase class II core domain (G, H, P, S and T) , score 193.6, E-value 2.1e-55 272560014348 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560014349 Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671 272560014350 putative active site [active] 272560014351 Ap4A binding site [chemical binding]; other site 272560014352 nudix motif; other site 272560014353 putative metal binding site [ion binding]; other site 272560014354 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 80.2, E-value 2.8e-21 272560014355 PS00893 mutT domain signature. 272560014356 Signal peptide predicted for BPSL3000 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.883 between residues 33 and 34; signal peptide 272560014357 CNP1-like family; Region: CNP1; pfam08750 272560014358 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014359 Transposase domain (DUF772); Region: DUF772; pfam05598 272560014360 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 272560014361 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560014362 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score -2.6, E-value 0.0072 272560014363 gamma-glutamyl kinase; Provisional; Region: PRK05429 272560014364 AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242 272560014365 nucleotide binding site [chemical binding]; other site 272560014366 homotetrameric interface [polypeptide binding]; other site 272560014367 putative phosphate binding site [ion binding]; other site 272560014368 putative allosteric binding site; other site 272560014369 PUA domain; Region: PUA; pfam01472 272560014370 Pfam match to entry PF01472 PUA, PUA domain , score 56.3, E-value 4.4e-14 272560014371 Pfam match to entry PF00696 aakinase, Amino acid kinase , score 214.2, E-value 1.3e-61 272560014372 PS00902 Glutamate 5-kinase signature. 272560014373 GTPase CgtA; Reviewed; Region: obgE; PRK12298 272560014374 GTP1/OBG; Region: GTP1_OBG; pfam01018 272560014375 Obg GTPase; Region: Obg; cd01898 272560014376 G1 box; other site 272560014377 GTP/Mg2+ binding site [chemical binding]; other site 272560014378 Switch I region; other site 272560014379 G2 box; other site 272560014380 G3 box; other site 272560014381 Switch II region; other site 272560014382 G4 box; other site 272560014383 G5 box; other site 272560014384 Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG family , score 382.9, E-value 2.2e-112 272560014385 PS00905 GTP1/OBG family signature. 272560014386 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014387 50S ribosomal protein L27; Validated; Region: rpmA; PRK05435 272560014388 Pfam match to entry PF01016 Ribosomal_L27, Ribosomal L27 protein , score 176.3, E-value 3.3e-50 272560014389 PS00831 Ribosomal protein L27 signature. 272560014390 50S ribosomal protein L21; Validated; Region: rplU; PRK05573 272560014391 Pfam match to entry PF00829 Ribosomal_L21p, Ribosomal prokaryotic L21 protein , score 152.1, E-value 6.4e-43 272560014392 PS01169 Ribosomal protein L21 signature. 272560014393 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 272560014394 substrate binding pocket [chemical binding]; other site 272560014395 chain length determination region; other site 272560014396 substrate-Mg2+ binding site; other site 272560014397 catalytic residues [active] 272560014398 aspartate-rich region 1; other site 272560014399 active site lid residues [active] 272560014400 aspartate-rich region 2; other site 272560014401 Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetase , score 290.1, E-value 1.8e-84 272560014402 PS00723 Polyprenyl synthetases signature 1. 272560014403 Signal peptide predicted for BPSL3007 by SignalP 2.0 HMM (Signal peptide probabilty 0.901) with cleavage site probability 0.318 between residues 26 and 27; signal peptide 272560014404 Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism]; Region: CorB; COG4536 272560014405 Domain of unknown function DUF21; Region: DUF21; pfam01595 272560014406 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 272560014407 Transporter associated domain; Region: CorC_HlyC; smart01091 272560014408 4 probable transmembrane helices predicted for BPSL3007 by TMHMM2.0 at aa 4-26, 62-84, 94-113 and 126-148 272560014409 Pfam match to entry PF01595 DUF21, Domain of unknown function DUF21 , score 150.3, E-value 2.2e-42 272560014410 Pfam match to entry PF00571 CBS, CBS domain , score 24.4, E-value 0.00017 272560014411 Pfam match to entry PF00571 CBS, CBS domain , score 41.5, E-value 1.3e-09 272560014412 Pfam match to entry PF03471 CorC_HlyC, Transporter associated domain , score 45.8, E-value 6.4e-11 272560014413 PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129 272560014414 Walker A motif; other site 272560014415 ATP binding site [chemical binding]; other site 272560014416 Walker B motif; other site 272560014417 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score 498.1, E-value 4.4e-147 272560014418 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014419 PS00662 Bacterial type II secretion system protein E signature. 272560014420 Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459 272560014421 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560014422 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560014423 Pfam match to entry PF00482 GSPII_F, Bacterial type II secretion system protein F domain , score 308.5, E-value 5e-90 272560014424 4 probable transmembrane helices predicted for BPSL3009 by TMHMM2.0 at aa 131-150, 171-193, 213-235 and 377-399 272560014425 PS00874 Bacterial type II secretion system protein F signature. 272560014426 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989 272560014427 Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750 272560014428 Type IV leader peptidase family; Region: Peptidase_A24; pfam01478 272560014429 Pfam match to entry PF01478 Peptidase_C20, Type IV leader peptidase , score 397.7, E-value 7.2e-117 272560014430 7 probable transmembrane helices predicted for BPSL3010 by TMHMM2.0 at aa 33-55, 128-150, 155-172, 179-201, 205-227, 248-270 and 285-307 272560014431 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560014432 Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237 272560014433 Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022 272560014434 CoA-binding site [chemical binding]; other site 272560014435 ATP-binding [chemical binding]; other site 272560014436 Pfam match to entry PF01121 CoaE, Dephospho-CoA kinase , score 260.1, E-value 1.9e-75 272560014437 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014438 hypothetical protein; Provisional; Region: PRK05287 272560014439 Domain of unknown function (DUF329); Region: DUF329; pfam03884 272560014440 The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425 272560014441 active site 272560014442 8-oxo-dGMP binding site [chemical binding]; other site 272560014443 nudix motif; other site 272560014444 metal binding site [ion binding]; metal-binding site 272560014445 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 80.1, E-value 2.9e-21 272560014446 PS00893 mutT domain signature. 272560014447 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560014448 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 272560014449 Walker A motif; other site 272560014450 ATP binding site [chemical binding]; other site 272560014451 Walker B motif; other site 272560014452 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014453 Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152 272560014454 heterotetramer interface [polypeptide binding]; other site 272560014455 active site pocket [active] 272560014456 cleavage site 272560014457 Pfam match to entry PF01960 ArgJ, ArgJ family , score 609.5, E-value 1.3e-180 272560014458 preprotein translocase subunit SecA; Reviewed; Region: PRK12904 272560014459 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251 272560014460 SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958 272560014461 SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516 272560014462 SEC-C motif; Region: SEC-C; pfam02810 272560014463 Pfam match to entry PF02810 SEC-C, SEC-C motif , score 45.6, E-value 7.1e-11 272560014464 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 0.4, E-value 0.015 272560014465 PS01312 Protein secA signatures. 272560014466 Pfam match to entry PF01043 SecA_protein, SecA protein, amino terminal region , score 1020.9, E-value 1.8e-304 272560014467 Protein of unknown function (DUF721); Region: DUF721; pfam05258 272560014468 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186 272560014469 UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331 272560014470 Pfam match to entry PF03331 LpxC, UDP-3-O-acyl N-acetylglycosamine deacetylase , score 522.2, E-value 2.5e-154 272560014471 Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5...; Region: PRX5_like; cd03013 272560014472 catalytic triad [active] 272560014473 dimer interface [polypeptide binding]; other site 272560014474 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 49.7, E-value 4.1e-12 272560014475 cell division protein FtsZ; Validated; Region: PRK09330 272560014476 FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes. FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201 272560014477 nucleotide binding site [chemical binding]; other site 272560014478 SulA interaction site; other site 272560014479 Pfam match to entry PF03953 tubulin_C, Tubulin/FtsZ family, C-terminal domain , score 108.2, E-value 1e-29 272560014480 Pfam match to entry PF00091 tubulin, Tubulin/FtsZ family, GTPase domain , score 280.3, E-value 1.6e-81 272560014481 PS01135 FtsZ protein signature 2. 272560014482 Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849 272560014483 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 272560014484 nucleotide binding site [chemical binding]; other site 272560014485 SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491 272560014486 Cell division protein FtsA; Region: FtsA; pfam14450 272560014487 Pfam match to entry PF02491 FtsA, Cell division protein FtsA , score 192.8, E-value 3.5e-55 272560014488 Pfam match to entry PF02491 FtsA, Cell division protein FtsA , score 194.2, E-value 1.4e-55 272560014489 Signal peptide predicted for BPSL3022 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.590 between residues 24 and 25; signal peptide 272560014490 Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589 272560014491 POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478 272560014492 Cell division protein FtsQ; Region: FtsQ; pfam03799 272560014493 Pfam match to entry PF03799 FtsQ, Cell division protein FtsQ , score 111.3, E-value 1.2e-30 272560014494 1 probable transmembrane helix predicted for BPSL3022 by TMHMM2.0 at aa 10-32 272560014495 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014496 D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372 272560014497 D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820 272560014498 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560014499 Pfam match to entry PF01820 Dala_Dala_ligas, D-ala D-ala ligase , score 357.9, E-value 7.3e-105 272560014500 UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421 272560014501 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 272560014502 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560014503 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560014504 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 88.0, E-value 1.3e-23 272560014505 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 217.1, E-value 1.8e-62 272560014506 undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726 272560014507 MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785 272560014508 active site 272560014509 homodimer interface [polypeptide binding]; other site 272560014510 Pfam match to entry PF03033 Glyco_transf_28, Glycosyltransferase 28 , score 341.5, E-value 6.3e-100 272560014511 1 probable transmembrane helix predicted for BPSL3025 by TMHMM2.0 at aa 126-145 272560014512 cell division protein FtsW; Region: ftsW; TIGR02614 272560014513 Pfam match to entry PF01098 FTSW_RODA_SPOVE, Cell cycle protein , score 422.5, E-value 2.5e-124 272560014514 10 probable transmembrane helices predicted for BPSL3026 by TMHMM2.0 at aa 60-82, 97-116, 129-146, 161-183, 195-212, 216-235, 240-257, 318-340, 360-378 and 393-415 272560014515 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK02006 272560014516 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560014517 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560014518 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 33.8, E-value 2.5e-07 272560014519 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 130.6, E-value 1.8e-36 272560014520 Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852 272560014521 Mg++ binding site [ion binding]; other site 272560014522 putative catalytic motif [active] 272560014523 putative substrate binding site [chemical binding]; other site 272560014524 10 probable transmembrane helices predicted for BPSL3028 by TMHMM2.0 at aa 22-44, 65-87, 97-114, 134-153, 194-216, 223-242, 257-279, 286-308, 312-334 and 367-386 272560014525 Pfam match to entry PF00953 Glycos_transf_4, Glycosyl transferase , score 193.3, E-value 2.5e-55 272560014526 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560014527 UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770 272560014528 Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225 272560014529 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560014530 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560014531 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 51.6, E-value 1.2e-12 272560014532 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 173.3, E-value 2.6e-49 272560014533 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139 272560014534 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560014535 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560014536 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 116.5, E-value 3.3e-32 272560014537 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 172.0, E-value 6.6e-49 272560014538 Signal peptide predicted for BPSL3031 by SignalP 2.0 HMM (Signal peptide probabilty 0.630) with cleavage site probability 0.456 between residues 43 and 44; signal peptide 272560014539 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 272560014540 Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717 272560014541 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 272560014542 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 341.8, E-value 5.1e-100 272560014543 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014544 Pfam match to entry PF03717 PBP_dimer, Penicillin-binding Protein dimerisation domain , score 169.3, E-value 4.1e-48 272560014545 1 probable transmembrane helix predicted for BPSL3031 by TMHMM2.0 at aa 30-49 272560014546 cell division protein FtsL; Region: ftsL_broad; TIGR02209 272560014547 Signal peptide predicted for BPSL3032 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.578 between residues 21 and 22; signal peptide 272560014548 1 probable transmembrane helix predicted for BPSL3032 by TMHMM2.0 at aa 4-21 272560014549 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014550 16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050 272560014551 Pfam match to entry PF01795 Methyltransf_5, MraW methylase , score 451.3, E-value 5.4e-133 272560014552 cell division protein MraZ; Reviewed; Region: PRK00326 272560014553 MraZ protein; Region: MraZ; pfam02381 272560014554 MraZ protein; Region: MraZ; pfam02381 272560014555 Pfam match to entry PF02381 UPF0040, Domain of unknown function UPF0040 family , score 58.3, E-value 1.1e-14 272560014556 Pfam match to entry PF02381 UPF0040, Domain of unknown function UPF0040 family , score 45.9, E-value 5.7e-11 272560014557 Demethoxyubiquinone hydroxylase, ferritin-like diiron-binding domain; Region: DMQH; cd01042 272560014558 diiron binding motif [ion binding]; other site 272560014559 Signal peptide predicted for BPSL3036 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 20 and 21; signal peptide 272560014560 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560014561 trimer interface [polypeptide binding]; other site 272560014562 eyelet of channel; other site 272560014563 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -56.9, E-value 0.00051 272560014564 Long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07059 272560014565 Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936 272560014566 acyl-activating enzyme (AAE) consensus motif; other site 272560014567 putative AMP binding site [chemical binding]; other site 272560014568 putative active site [active] 272560014569 putative CoA binding site [chemical binding]; other site 272560014570 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 422.2, E-value 3e-124 272560014571 1 probable transmembrane helix predicted for BPSL3037 by TMHMM2.0 at aa 253-275 272560014572 PS00455 AMP-binding domain signature. 272560014573 The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766 272560014574 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 272560014575 putative [4Fe-4S] binding site [ion binding]; other site 272560014576 putative molybdopterin cofactor binding site [chemical binding]; other site 272560014577 The MopB_CT_3 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_3; cd02786 272560014578 putative molybdopterin cofactor binding site; other site 272560014579 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 76.1, E-value 4.9e-20 272560014580 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 244.2, E-value 1.2e-70 272560014581 PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 272560014582 enoyl-CoA hydratase; Provisional; Region: PRK05862 272560014583 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560014584 substrate binding site [chemical binding]; other site 272560014585 oxyanion hole (OAH) forming residues; other site 272560014586 trimer interface [polypeptide binding]; other site 272560014587 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 252.8, E-value 3.1e-73 272560014588 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560014589 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560014590 NAD(P) binding site [chemical binding]; other site 272560014591 catalytic residues [active] 272560014592 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score -151.0, E-value 6e-09 272560014593 beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050 272560014594 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560014595 dimer interface [polypeptide binding]; other site 272560014596 active site 272560014597 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 333.1, E-value 2e-97 272560014598 PS00098 Thiolases acyl-enzyme intermediate signature. 272560014599 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 207.0, E-value 1.9e-59 272560014600 PS00737 Thiolases signature 2. 272560014601 PS00099 Thiolases active site. 272560014602 enoyl-CoA hydratase; Provisional; Region: PRK08140 272560014603 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560014604 substrate binding site [chemical binding]; other site 272560014605 oxyanion hole (OAH) forming residues; other site 272560014606 trimer interface [polypeptide binding]; other site 272560014607 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 205.7, E-value 4.6e-59 272560014608 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560014609 CoenzymeA binding site [chemical binding]; other site 272560014610 subunit interaction site [polypeptide binding]; other site 272560014611 PHB binding site; other site 272560014612 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 106.8, E-value 2.7e-29 272560014613 Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913 272560014614 phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155 272560014615 active site 272560014616 AMP binding site [chemical binding]; other site 272560014617 homodimer interface [polypeptide binding]; other site 272560014618 acyl-activating enzyme (AAE) consensus motif; other site 272560014619 CoA binding site [chemical binding]; other site 272560014620 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 9.6, E-value 0.0082 272560014621 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 31.8, E-value 5.9e-09 272560014622 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 17.8, E-value 4.3e-05 272560014623 Membrane-bound lytic murein transglycosylase [Cell envelope biogenesis, outer membrane]; Region: MltA; COG2821 272560014624 MltA specific insert domain; Region: MltA; smart00925 272560014625 3D domain; Region: 3D; pfam06725 272560014626 Pfam match to entry PF03562 MltA, MltA family , score 383.1, E-value 1.8e-112 272560014627 CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461 272560014628 Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429 272560014629 substrate binding site [chemical binding]; other site 272560014630 hexamer interface [polypeptide binding]; other site 272560014631 metal binding site [ion binding]; metal-binding site 272560014632 Pfam match to entry PF00834 Ribul_P_3_epim, Ribulose-phosphate 3 epimerase , score 462.9, E-value 1.7e-136 272560014633 PS01085 Ribulose-phosphate 3-epimerase signature 1. 272560014634 PS01086 Ribulose-phosphate 3-epimerase signature 2. 272560014635 phosphoglycolate phosphatase; Provisional; Region: PRK13222 272560014636 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560014637 motif II; other site 272560014638 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 133.1, E-value 3.3e-37 272560014639 anthranilate synthase component I; Provisional; Region: PRK13565 272560014640 Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715 272560014641 chorismate binding enzyme; Region: Chorismate_bind; pfam00425 272560014642 Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme , score 516.1, E-value 1.6e-152 272560014643 para-aminobenzoate synthase component II; Provisional; Region: PRK08857 272560014644 Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743 272560014645 glutamine binding [chemical binding]; other site 272560014646 catalytic triad [active] 272560014647 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 313.2, E-value 1.9e-91 272560014648 PS00442 Glutamine amidotransferases class-I active site. 272560014649 anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188 272560014650 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 272560014651 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 272560014652 Pfam match to entry PF02885 Glycos_trans_3N, Glycosyl transferase, helical bundle domain , score 41.4, E-value 1.3e-09 272560014653 Pfam match to entry PF00591 Glycos_transf_3, Glycosyl transferase, a/b domain , score 418.2, E-value 4.9e-123 272560014654 Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331 272560014655 active site 272560014656 ribulose/triose binding site [chemical binding]; other site 272560014657 phosphate binding site [ion binding]; other site 272560014658 substrate (anthranilate) binding pocket [chemical binding]; other site 272560014659 product (indole) binding pocket [chemical binding]; other site 272560014660 Pfam match to entry PF00218 IGPS, Indole-3-glycerol phosphate synthase , score 443.0, E-value 1.7e-130 272560014661 PS00614 Indole-3-glycerol phosphate synthase signature. 272560014662 Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756 272560014663 putative active site [active] 272560014664 putative metal binding residues [ion binding]; other site 272560014665 signature motif; other site 272560014666 putative triphosphate binding site [ion binding]; other site 272560014667 Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027 272560014668 ligand binding site [chemical binding]; other site 272560014669 active site 272560014670 UGI interface [polypeptide binding]; other site 272560014671 catalytic site [active] 272560014672 Pfam match to entry PF03167 UDG, Uracil DNA glycosylase superfamily , score 258.1, E-value 7.5e-75 272560014673 PS00130 Uracil-DNA glycosylase signature. 272560014674 NADPH-dependent FMN reductase; Region: FMN_red; cl00438 272560014675 Pfam match to entry PF02525 Flavodoxin_2, Flavodoxin-like fold , score 146.8, E-value 2.4e-41 272560014676 Predicted protease with the C-terminal PDZ domain [General function prediction only]; Region: COG3975 272560014677 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 272560014678 M61 glycyl aminopeptidase; Region: Peptidase_M61; pfam05299 272560014679 Zn binding site [ion binding]; other site 272560014680 PDZ domain; Region: PDZ_2; pfam13180 272560014681 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 17.2, E-value 0.0013 272560014682 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560014683 Signal peptide predicted for BPSL3058 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.968 between residues 28 and 29; signal peptide 272560014684 protein disulfide isomerase II DsbC; Provisional; Region: PRK10877 272560014685 DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020 272560014686 dimerization domain [polypeptide binding]; other site 272560014687 dimer interface [polypeptide binding]; other site 272560014688 catalytic residues [active] 272560014689 PS00194 Thioredoxin family active site. 272560014690 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014691 ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608 272560014692 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988 272560014693 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 118.3, E-value 9.5e-33 272560014694 PS01304 ubiH/COQ6 monooxygenase signature. 272560014695 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014696 1 probable transmembrane helix predicted for BPSL3060 by TMHMM2.0 at aa 17-39 272560014697 GTP-binding protein YchF; Reviewed; Region: PRK09601 272560014698 YchF GTPase; Region: YchF; cd01900 272560014699 G1 box; other site 272560014700 GTP/Mg2+ binding site [chemical binding]; other site 272560014701 Switch I region; other site 272560014702 G2 box; other site 272560014703 Switch II region; other site 272560014704 G3 box; other site 272560014705 G4 box; other site 272560014706 G5 box; other site 272560014707 TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867 272560014708 Pfam match to entry PF01018 GTP1_OBG, GTP1/OBG family , score 15.6, E-value 0.00018 272560014709 NADH dehydrogenase subunit B; Validated; Region: PRK06411 272560014710 Pfam match to entry PF01058 oxidored_q6, NADH ubiquinone oxidoreductase, 20 Kd subunit , score 216.7, E-value 2.3e-62 272560014711 PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 272560014712 Tryptophan 2,3-dioxygenase; Region: Trp_dioxygenase; cl03994 272560014713 Helix-turn-helix domain; Region: HTH_18; pfam12833 272560014714 gamma-aminobutyrate permease; Region: GABAperm; TIGR01773 272560014715 Spore germination protein; Region: Spore_permease; cl17796 272560014716 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 620.2, E-value 7.6e-184 272560014717 12 probable transmembrane helices predicted for BPSL3065 by TMHMM2.0 at aa 30-52, 57-76, 97-119, 134-156, 168-190, 205-227, 251-273, 298-320, 347-366, 370-392, 412-434 and 439-456 272560014718 PS00218 Amino acid permeases signature. 272560014719 Signal peptide predicted for BPSL3066 by SignalP 2.0 HMM (Signal peptide probabilty 0.788) with cleavage site probability 0.295 between residues 27 and 28; signal peptide 272560014720 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 272560014721 Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580 272560014722 putative active site [active] 272560014723 catalytic site [active] 272560014724 putative metal binding site [ion binding]; other site 272560014725 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase , score 91.0, E-value 1.6e-24 272560014726 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014727 putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819 272560014728 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560014729 ABC transporter; Region: ABC_tran_2; pfam12848 272560014730 ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221 272560014731 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 178.8, E-value 5.6e-51 272560014732 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014733 PS00211 ABC transporters family signature. 272560014734 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 159.1, E-value 4.8e-45 272560014735 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014736 haloacid dehalogenase-like hydrolase; Region: HAD; cl19137 272560014737 Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419 272560014738 REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252 272560014739 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 41.8, E-value 1e-09 272560014740 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220 272560014741 catalytic triad [active] 272560014742 conserved cis-peptide bond; other site 272560014743 Pfam match to entry PF00857 Isochorismatase, Isochorismatase , score 33.2, E-value 1.5e-07 272560014744 Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321 272560014745 Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006 272560014746 X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085 272560014747 active site 272560014748 Pfam match to entry PF00557 Peptidase_M24, metallopeptidase M24 , score 47.4, E-value 2.1e-11 272560014749 3 probable transmembrane helices predicted for BPSL3071 by TMHMM2.0 at aa 44-66, 76-98 and 105-127 272560014750 glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045 272560014751 NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213 272560014752 tRNA; other site 272560014753 putative tRNA binding site [nucleotide binding]; other site 272560014754 putative NADP binding site [chemical binding]; other site 272560014755 Glutamyl-tRNAGlu reductase, dimerization domain; Region: GlutR_dimer; pfam00745 272560014756 Pfam match to entry PF00745 GlutR, Glutamyl-tRNAGlu reductase , score 578.7, E-value 2.3e-171 272560014757 peptide chain release factor 1; Validated; Region: prfA; PRK00591 272560014758 This domain is found in peptide chain release factors; Region: PCRF; smart00937 272560014759 RF-1 domain; Region: RF-1; pfam00472 272560014760 Pfam match to entry PF03462 PCRF, PCRF domain , score 218.0, E-value 9.1e-63 272560014761 Pfam match to entry PF00472 RF-1, Peptidyl-tRNA hydrolase domain , score 241.9, E-value 5.7e-70 272560014762 N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328 272560014763 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560014764 S-adenosylmethionine binding site [chemical binding]; other site 272560014765 Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028 272560014766 putative GSH binding site [chemical binding]; other site 272560014767 catalytic residues [active] 272560014768 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029 272560014769 Pfam match to entry PF02441 Flavoprotein, Flavoprotein , score 162.9, E-value 3.6e-46 272560014770 The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363 272560014771 putative active site [active] 272560014772 metal binding site [ion binding]; metal-binding site 272560014773 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 272560014774 Signal peptide predicted for BPSL3078 by SignalP 2.0 HMM (Signal peptide probabilty 0.925) with cleavage site probability 0.469 between residues 33 and 34; signal peptide 272560014775 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560014776 14 probable transmembrane helices predicted for BPSL3078 by TMHMM2.0 at aa 9-31, 46-68, 81-103, 129-151, 164-183, 198-220, 240-262, 277-299, 339-361, 366-388, 400-422, 426-445, 458-477 and 487-509 272560014777 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -124.0, E-value 2.5e-07 272560014778 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 272560014779 DNA-binding site [nucleotide binding]; DNA binding site 272560014780 RNA-binding motif; other site 272560014781 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain , score 145.9, E-value 4.5e-41 272560014782 PS00352 'Cold-shock' DNA-binding domain signature. 272560014783 putative chaperone; Provisional; Region: PRK11678 272560014784 Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231 272560014785 nucleotide binding site [chemical binding]; other site 272560014786 putative NEF/HSP70 interaction site [polypeptide binding]; other site 272560014787 SBD interface [polypeptide binding]; other site 272560014788 Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138 272560014789 putative FMN binding site [chemical binding]; other site 272560014790 Pfam match to entry PF00881 Nitroreductase, Nitroreductase , score 45.0, E-value 1.1e-10 272560014791 Signal peptide predicted for BPSL3082 by SignalP 2.0 HMM (Signal peptide probabilty 0.982) with cleavage site probability 0.485 between residues 34 and 35; signal peptide 272560014792 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560014793 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560014794 putative substrate translocation pore; other site 272560014795 12 probable transmembrane helices predicted for BPSL3082 by TMHMM2.0 at aa 12-34, 54-76, 83-105, 109-131, 144-166, 171-193, 241-263, 278-297, 304-326, 331-353, 365-387 and 391-413 272560014796 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560014797 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560014798 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 68.6, E-value 8.8e-18 272560014799 Protein of unknown function (DUF1415); Region: DUF1415; pfam07209 272560014800 Methyltransferase domain; Region: Methyltransf_32; pfam13679 272560014801 Methylase of polypeptide chain release factors [Translation, ribosomal structure and biogenesis]; Region: HemK; COG2890 272560014802 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560014803 S-adenosylmethionine binding site [chemical binding]; other site 272560014804 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560014805 9 probable transmembrane helices predicted for BPSL3087 by TMHMM2.0 at aa 81-103, 116-138, 167-189, 196-215, 225-239, 260-282, 292-311, 318-340 and 355-372 272560014806 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 27.9, E-value 2.1e-07 272560014807 Water Stress and Hypersensitive response; Region: WHy; smart00769 272560014808 Signal peptide predicted for BPSL3089 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.259 between residues 47 and 48; signal peptide 272560014809 Aminopeptidase N [Amino acid transport and metabolism]; Region: PepN; COG0308 272560014810 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 272560014811 Zn binding site [ion binding]; other site 272560014812 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014813 Pfam match to entry PF01433 Peptidase_M1, Peptidase M1 , score 197.6, E-value 1.3e-56 272560014814 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560014815 1 probable transmembrane helix predicted for BPSL3091 by TMHMM2.0 at aa 10-32 272560014816 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 272560014817 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560014818 Monopolin complex subunit LRS4; Region: LRS4; pfam10422 272560014819 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560014820 1 probable transmembrane helix predicted for BPSL3092 by TMHMM2.0 at aa 30-52 272560014821 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274 272560014822 A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39C; cd02419 272560014823 putative active site [active] 272560014824 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560014825 ATP-binding cassette domain of PrtD, subfamily C; Region: ABCC_Protease_Secretion; cd03246 272560014826 Walker A/P-loop; other site 272560014827 ATP binding site [chemical binding]; other site 272560014828 Q-loop/lid; other site 272560014829 ABC transporter signature motif; other site 272560014830 Walker B; other site 272560014831 D-loop; other site 272560014832 H-loop/switch region; other site 272560014833 Pfam match to entry PF03412 Peptidase_C39, Peptidase C39 family , score 140.6, E-value 1.8e-39 272560014834 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 117.6, E-value 1.5e-32 272560014835 5 probable transmembrane helices predicted for BPSL3093 by TMHMM2.0 at aa 173-195, 210-232, 283-305, 309-328 and 398-417 272560014836 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 202.3, E-value 4.8e-58 272560014837 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014838 PS00211 ABC transporters family signature. 272560014839 Signal peptide predicted for BPSL3094 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.989 between residues 26 and 27; signal peptide 272560014840 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 272560014841 Outer membrane efflux protein; Region: OEP; pfam02321 272560014842 Outer membrane efflux protein; Region: OEP; pfam02321 272560014843 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 98.2, E-value 1.1e-26 272560014844 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 137.7, E-value 1.3e-38 272560014845 D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557 272560014846 D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539 272560014847 Type VI protein secretion system component VasK [Intracellular trafficking, secretion, and vesicular transport]; Region: IcmF; COG3523 272560014848 Signal peptide predicted for BPSL3097 by SignalP 2.0 HMM (Signal peptide probabilty 0.997) with cleavage site probability 0.706 between residues 40 and 41; signal peptide 272560014849 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560014850 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 272560014851 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560014852 3 probable transmembrane helices predicted for BPSL3097 by TMHMM2.0 at aa 13-30, 35-57 and 440-462 272560014853 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014854 Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; cl01611 272560014855 Signal peptide predicted for BPSL3099 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.973 between residues 29 and 30; signal peptide 272560014856 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 272560014857 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560014858 ligand binding site [chemical binding]; other site 272560014859 Pfam match to entry PF00691 OmpA, OmpA family , score 132.9, E-value 3.7e-37 272560014860 type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363 272560014861 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 272560014862 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560014863 Clp amino terminal domain; Region: Clp_N; pfam02861 272560014864 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560014865 Walker A motif; other site 272560014866 ATP binding site [chemical binding]; other site 272560014867 Walker B motif; other site 272560014868 arginine finger; other site 272560014869 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560014870 Walker A motif; other site 272560014871 ATP binding site [chemical binding]; other site 272560014872 Walker B motif; other site 272560014873 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560014874 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014875 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 29.7, E-value 3.6e-07 272560014876 PS00870 Chaperonins clpA/B signature 1. 272560014877 PS00017 ATP/GTP-binding site motif A (P-loop). 272560014878 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain , score 25.4, E-value 8.5e-05 272560014879 type VI secretion protein, VC_A0111 family; Region: VI_chp_1; TIGR03347 272560014880 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 272560014881 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3518 272560014882 Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion, and vesicular transport]; Region: Hcp; COG3157 272560014883 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 272560014884 Protein of unknown function (DUF770); Region: DUF770; pfam05591 272560014885 Signal peptide predicted for BPSL3108 by SignalP 2.0 HMM (Signal peptide probabilty 0.952) with cleavage site probability 0.654 between residues 24 and 25; signal peptide 272560014886 Tetratricopeptide repeat; Region: TPR_16; pfam13432 272560014887 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560014888 TPR motif; other site 272560014889 binding surface 272560014890 Pfam match to entry PF00515 TPR, TPR Domain , score 24.2, E-value 0.0002 272560014891 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014892 Signal peptide predicted for BPSL3109 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.361 between residues 24 and 25; signal peptide 272560014893 type VI secretion lipoprotein, VC_A0113 family; Region: VI_chp_3; TIGR03352 272560014894 1 probable transmembrane helix predicted for BPSL3109 by TMHMM2.0 at aa 7-29 272560014895 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560014896 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 272560014897 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560014898 1 probable transmembrane helix predicted for BPSL3111 by TMHMM2.0 at aa 210-232 272560014899 Partial CDS, probable gene remnant. Similar to the C-terminal regions of Escherichia coli CP4-like integrase Int or Intl or z5087 or ecs4534 SWALL:O85610 (EMBL:AF071034) (393 aa) fasta scores: E(): 1.7e-13, 47.52% id in 101 aa, and Bacteriophage P4 Integrase Int SWALL:VINT_BPP4 (SWALL:P08320) (439 aa) fasta scores: E(): 3.8e-09, 47.12% id in 87 aa; integrase (fragment) 272560014900 Genomic island GI 10 272560014901 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560014902 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560014903 non-specific DNA binding site [nucleotide binding]; other site 272560014904 salt bridge; other site 272560014905 sequence-specific DNA binding site [nucleotide binding]; other site 272560014906 Predicted Zn peptidase [Amino acid transport and metabolism]; Region: COG2856 272560014907 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 58.8, E-value 7.6e-15 272560014908 Transposase; Region: HTH_Tnp_1; pfam01527 272560014909 Pfam match to entry PF01527 Transposase_8, Transposase , score 134.4, E-value 1.3e-37 272560014910 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801 272560014911 HTH-like domain; Region: HTH_21; pfam13276 272560014912 Integrase core domain; Region: rve; pfam00665 272560014913 Integrase core domain; Region: rve_3; pfam13683 272560014914 Pfam match to entry PF00665 rve, Integrase core domain , score 148.5, E-value 7.5e-42 272560014915 Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958 272560014916 Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286 272560014917 Methyltransferase domain; Region: Methyltransf_26; pfam13659 272560014918 PS00092 N-6 Adenine-specific DNA methylases signature. 272560014919 Pfam match to entry PF02506 Methylase_M, Type I restriction modification system, M protein , score -77.6, E-value 1.8e-05 272560014920 ClpXP protease specificity-enhancing factor; Provisional; Region: PRK11798 272560014921 stringent starvation protein A; Provisional; Region: sspA; PRK09481 272560014922 GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059 272560014923 C-terminal domain interface [polypeptide binding]; other site 272560014924 putative GSH binding site (G-site) [chemical binding]; other site 272560014925 dimer interface [polypeptide binding]; other site 272560014926 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 272560014927 N-terminal domain interface [polypeptide binding]; other site 272560014928 dimer interface [polypeptide binding]; other site 272560014929 substrate binding pocket (H-site) [chemical binding]; other site 272560014930 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 15.0, E-value 0.00041 272560014931 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 70.2, E-value 2.8e-18 272560014932 Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857 272560014933 Signal peptide predicted for BPSL3121 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.965 between residues 25 and 26; signal peptide 272560014934 Cytochrome C1 family; Region: Cytochrom_C1; pfam02167 272560014935 Pfam match to entry PF02167 Cytochrome_C1, Cytochrome C1 family , score -68.3, E-value 4.2e-08 272560014936 1 probable transmembrane helix predicted for BPSL3121 by TMHMM2.0 at aa 224-246 272560014937 PS00190 Cytochrome c family heme-binding site signature. 272560014938 Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290 272560014939 Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284 272560014940 Qi binding site; other site 272560014941 intrachain domain interface; other site 272560014942 interchain domain interface [polypeptide binding]; other site 272560014943 heme bH binding site [chemical binding]; other site 272560014944 heme bL binding site [chemical binding]; other site 272560014945 Qo binding site; other site 272560014946 interchain domain interface [polypeptide binding]; other site 272560014947 intrachain domain interface; other site 272560014948 Qi binding site; other site 272560014949 Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032 272560014950 Qo binding site; other site 272560014951 11 probable transmembrane helices predicted for BPSL3122 by TMHMM2.0 at aa 42-64, 89-111, 126-148, 160-179, 194-216, 254-276, 311-333, 340-357, 361-380, 393-413 and 423-445 272560014952 Pfam match to entry PF00032 cytochrome_b_C, Cytochrome b(C-terminal)/b6/petD , score 25.3, E-value 8.8e-07 272560014953 Pfam match to entry PF00033 cytochrome_b_N, Cytochrome b(N-terminal)/b6/petB , score 294.9, E-value 6.6e-86 272560014954 PS00192 Cytochrome b/b6 heme-ligand signature. 272560014955 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal; Region: UCR_Fe-S_N; pfam10399 272560014956 ubiquinol-cytochrome c reductase, iron-sulfur subunit; Region: Rieske_proteo; TIGR01416 272560014957 Signal peptide predicted for BPSL3123 by SignalP 2.0 HMM (Signal peptide probabilty 0.885) with cleavage site probability 0.878 between residues 16 and 17; signal peptide 272560014958 Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470 272560014959 [2Fe-2S] cluster binding site [ion binding]; other site 272560014960 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 15.2, E-value 2.7e-05 272560014961 PS00200 Rieske iron-sulfur protein signature 2. 272560014962 PS00199 Rieske iron-sulfur protein signature 1. 272560014963 NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371 272560014964 Pfam match to entry PF01784 DUF34, Domain of unknown function DUF34 , score 276.3, E-value 2.7e-80 272560014965 Signal peptide predicted for BPSL3125 by SignalP 2.0 HMM (Signal peptide probabilty 0.916) with cleavage site probability 0.312 between residues 26 and 27; signal peptide 272560014966 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265 272560014967 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 272560014968 PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987 272560014969 protein binding site [polypeptide binding]; other site 272560014970 1 probable transmembrane helix predicted for BPSL3125 by TMHMM2.0 at aa 5-24 272560014971 Pfam match to entry PF00089 trypsin, Trypsin , score 81.1, E-value 1.5e-21 272560014972 Pfam match to entry PF00595 PDZ, PDZ domain (Also known as DHR or GLGF) , score 58.9, E-value 7.1e-15 272560014973 Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805 272560014974 6 probable transmembrane helices predicted for BPSL3126 by TMHMM2.0 at aa 27-49, 81-103, 123-145, 165-187, 200-218 and 223-245 272560014975 Pfam match to entry PF00902 UPF0032, MttB family UPF0032 , score 286.1, E-value 3e-83 272560014976 sec-independent translocase; Provisional; Region: tatB; PRK01919 272560014977 sec-independent translocase; Provisional; Region: tatB; PRK00404 272560014978 Pfam match to entry PF02416 MttA_Hcf106, mttA/Hcf106 family , score 13.6, E-value 0.00014 272560014979 twin arginine translocase protein A; Provisional; Region: tatA; PRK02958 272560014980 Pfam match to entry PF02416 MttA_Hcf106, mttA/Hcf106 family , score 36.5, E-value 3.9e-08 272560014981 1 probable transmembrane helix predicted for BPSL3128 by TMHMM2.0 at aa 4-21 272560014982 Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276 272560014983 nucleotide binding site/active site [active] 272560014984 HIT family signature motif; other site 272560014985 catalytic residue [active] 272560014986 Pfam match to entry PF01230 HIT, HIT family , score 152.9, E-value 3.5e-43 272560014987 Predicted membrane protein [Function unknown]; Region: COG3671 272560014988 2 probable transmembrane helices predicted for BPSL3130 by TMHMM2.0 at aa 38-60 and 89-111 272560014989 Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534 272560014990 metal binding site [ion binding]; metal-binding site 272560014991 Pfam match to entry PF01503 PRA-PH, Phosphoribosyl-ATP pyrophosphohydrolase , score 132.3, E-value 5.6e-37 272560014992 phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051 272560014993 Pfam match to entry PF01502 PRA-CH, Phosphoribosyl-AMP cyclohydrolase , score 186.0, E-value 3.9e-53 272560014994 The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731 272560014995 substrate binding site [chemical binding]; other site 272560014996 glutamase interaction surface [polypeptide binding]; other site 272560014997 Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein , score 483.5, E-value 1.1e-142 272560014998 HisA. Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732 272560014999 catalytic residues [active] 272560015000 Pfam match to entry PF00977 His_biosynth, Histidine biosynthesis protein , score 332.7, E-value 2.7e-97 272560015001 Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748 272560015002 imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142 272560015003 putative active site [active] 272560015004 oxyanion strand; other site 272560015005 catalytic triad [active] 272560015006 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 113.0, E-value 3.7e-31 272560015007 PS00442 Glutamine amidotransferases class-I active site. 272560015008 Signal peptide predicted for BPSL3136 by SignalP 2.0 HMM (Signal peptide probabilty 0.969) with cleavage site probability 0.505 between residues 28 and 29; signal peptide 272560015009 MarC family integral membrane protein; Region: MarC; cl00919 272560015010 Pfam match to entry PF01914 MarC, MarC family integral membrane protein , score 231.8, E-value 6.5e-67 272560015011 6 probable transmembrane helices predicted for BPSL3136 by TMHMM2.0 at aa 4-26, 39-61, 65-87, 111-133, 143-160 and 173-195 272560015012 Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914 272560015013 putative active site pocket [active] 272560015014 4-fold oligomerization interface [polypeptide binding]; other site 272560015015 metal binding residues [ion binding]; metal-binding site 272560015016 3-fold/trimer interface [polypeptide binding]; other site 272560015017 Pfam match to entry PF00475 IGPD, Imidazoleglycerol-phosphate dehydratase , score 311.7, E-value 5.8e-91 272560015018 PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 272560015019 PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 272560015020 histidinol-phosphate aminotransferase; Region: hisC; TIGR01141 272560015021 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560015022 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560015023 homodimer interface [polypeptide binding]; other site 272560015024 catalytic residue [active] 272560015025 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 103.3, E-value 3.1e-28 272560015026 Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141 272560015027 Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572 272560015028 NAD binding site [chemical binding]; other site 272560015029 dimerization interface [polypeptide binding]; other site 272560015030 product binding site; other site 272560015031 substrate binding site [chemical binding]; other site 272560015032 zinc binding site [ion binding]; other site 272560015033 catalytic residues [active] 272560015034 Pfam match to entry PF00815 Histidinol_dh, Histidinol dehydrogenase , score 621.3, E-value 3.7e-184 272560015035 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560015036 ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686 272560015037 ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040 272560015038 Pfam match to entry PF01634 HisG, ATP phosphoribosyltransferase , score 182.6, E-value 4.2e-52 272560015039 PS01316 ATP phosphoribosyltransferase signature. 272560015040 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275 272560015041 UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555 272560015042 hinge; other site 272560015043 active site 272560015044 Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) , score 511.4, E-value 4.4e-151 272560015045 BolA-like protein; Region: BolA; pfam01722 272560015046 Pfam match to entry PF01722 BolA, BolA-like protein , score 83.6, E-value 2.7e-22 272560015047 ABC-2 type transporter; Region: ABC2_membrane; cl17235 272560015048 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560015049 Pfam match to entry PF01061 ABC2_membrane, ABC-2 type transporter , score -26.6, E-value 5.4e-06 272560015050 7 probable transmembrane helices predicted for BPSL3143 by TMHMM2.0 at aa 15-37, 50-72, 87-106, 113-132, 136-158, 165-187 and 222-244 272560015051 PS00890 ABC-2 type transport system integral membrane proteins signature. 272560015052 ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131 272560015053 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 272560015054 Walker A/P-loop; other site 272560015055 ATP binding site [chemical binding]; other site 272560015056 Q-loop/lid; other site 272560015057 ABC transporter signature motif; other site 272560015058 Walker B; other site 272560015059 D-loop; other site 272560015060 H-loop/switch region; other site 272560015061 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 204.9, E-value 8.1e-59 272560015062 PS00211 ABC transporters family signature. 272560015063 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015064 Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043 272560015065 anti sigma factor interaction site; other site 272560015066 regulatory phosphorylation site [posttranslational modification]; other site 272560015067 Pfam match to entry PF01740 STAS, STAS domain , score 14.4, E-value 0.00033 272560015068 Signal peptide predicted for BPSL3146 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.968 between residues 23 and 24; signal peptide 272560015069 Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494 272560015070 Signal peptide predicted for BPSL3147 by SignalP 2.0 HMM (Signal peptide probabilty 0.933) with cleavage site probability 0.809 between residues 42 and 43; signal peptide 272560015071 VacJ like lipoprotein; Region: VacJ; cl01073 272560015072 1 probable transmembrane helix predicted for BPSL3147 by TMHMM2.0 at aa 21-43 272560015073 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015074 Signal peptide predicted for BPSL3148 by SignalP 2.0 HMM (Signal peptide probabilty 0.934) with cleavage site probability 0.387 between residues 43 and 44; signal peptide 272560015075 ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463 272560015076 mce related protein; Region: MCE; pfam02470 272560015077 Pfam match to entry PF02470 mce, mce related protein , score 139.1, E-value 5.1e-39 272560015078 1 probable transmembrane helix predicted for BPSL3148 by TMHMM2.0 at aa 7-28 272560015079 ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767 272560015080 Pfam match to entry PF02405 DUF140, Domain of unknown function DUF140 , score 317.2, E-value 1.3e-92 272560015081 5 probable transmembrane helices predicted for BPSL3149 by TMHMM2.0 at aa 46-68, 83-105, 153-175, 195-215 and 235-254 272560015082 ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127 272560015083 ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261 272560015084 Walker A/P-loop; other site 272560015085 ATP binding site [chemical binding]; other site 272560015086 Q-loop/lid; other site 272560015087 ABC transporter signature motif; other site 272560015088 Walker B; other site 272560015089 D-loop; other site 272560015090 H-loop/switch region; other site 272560015091 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 178.8, E-value 5.8e-51 272560015092 PS00211 ABC transporters family signature. 272560015093 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015094 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 272560015095 thiamine phosphate binding site [chemical binding]; other site 272560015096 active site 272560015097 pyrophosphate binding site [ion binding]; other site 272560015098 Pfam match to entry PF02581 TMP-TENI, Thiamine monophosphate synthase/TENI , score 162.5, E-value 4.7e-46 272560015099 Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728 272560015100 ThiS interaction site; other site 272560015101 putative active site [active] 272560015102 tetramer interface [polypeptide binding]; other site 272560015103 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 272560015104 ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565 272560015105 thiS-thiF/thiG interaction site; other site 272560015106 Pfam match to entry PF02597 DUF170, ThiS family , score 50.6, E-value 2.2e-12 272560015107 FAD dependent oxidoreductase; Region: DAO; pfam01266 272560015108 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560015109 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -54.2, E-value 4.5e-05 272560015110 ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178 272560015111 ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549 272560015112 ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223 272560015113 5 probable transmembrane helices predicted for BPSL3155 by TMHMM2.0 at aa 57-79, 99-121, 182-201, 211-233 and 304-326 272560015114 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 106.0, E-value 4.9e-29 272560015115 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015116 2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258 272560015117 LigT like Phosphoesterase; Region: LigT_PEase; pfam02834 272560015118 Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115 272560015119 Pfam match to entry PF01235 Na_Ala_symp, Sodium:alanine symporter family , score 640.3, E-value 7.1e-190 272560015120 9 probable transmembrane helices predicted for BPSL3157 by TMHMM2.0 at aa 15-34, 77-99, 143-165, 177-199, 209-231, 300-322, 349-371, 383-405 and 415-437 272560015121 PS00873 Sodium:alanine symporter family signature. 272560015122 glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810 272560015123 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691 272560015124 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560015125 Pfam match to entry PF01593 Amino_oxidase, Flavin containing amine oxidoreductase , score -21.8, E-value 5.7e-05 272560015126 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 118.0, E-value 1.2e-32 272560015127 glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750 272560015128 Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713 272560015129 active site 272560015130 dimer interface [polypeptide binding]; other site 272560015131 Glutamate synthase central domain; Region: Glu_syn_central; pfam04898 272560015132 Glutamate synthase (GltS) FMN-binding domain. GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808 272560015133 active site 272560015134 FMN binding site [chemical binding]; other site 272560015135 substrate binding site [chemical binding]; other site 272560015136 3Fe-4S cluster binding site [ion binding]; other site 272560015137 gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982 272560015138 domain interface; other site 272560015139 Pfam match to entry PF01493 DUF14, Domain of unknown function DUF14 , score 319.0, E-value 3.5e-93 272560015140 Pfam match to entry PF01645 Glu_synthase, Conserved region in glutamate synthase , score 780.7, E-value 3.6e-232 272560015141 Transposase IS200 like; Region: Y1_Tnp; cl00848 272560015142 Signal peptide predicted for BPSL3161 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.990 between residues 24 and 25; signal peptide 272560015143 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 272560015144 Pfam match to entry PF03922 OmpW, OmpW family , score 71.8, E-value 9.5e-19 272560015145 cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454 272560015146 Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562 272560015147 putative active site [active] 272560015148 catalytic site [active] 272560015149 putative metal binding site [ion binding]; other site 272560015150 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase , score 211.9, E-value 6.4e-61 272560015151 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 272560015152 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 272560015153 Walker A/P-loop; other site 272560015154 ATP binding site [chemical binding]; other site 272560015155 Q-loop/lid; other site 272560015156 ABC transporter signature motif; other site 272560015157 Walker B; other site 272560015158 D-loop; other site 272560015159 H-loop/switch region; other site 272560015160 TOBE domain; Region: TOBE_2; pfam08402 272560015161 Pfam match to entry PF03459 TOBE, TOBE domain , score 25.4, E-value 7.3e-07 272560015162 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 213.8, E-value 1.7e-61 272560015163 PS00211 ABC transporters family signature. 272560015164 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015165 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 272560015166 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560015167 dimer interface [polypeptide binding]; other site 272560015168 conserved gate region; other site 272560015169 putative PBP binding loops; other site 272560015170 ABC-ATPase subunit interface; other site 272560015171 7 probable transmembrane helices predicted for BPSL3164 by TMHMM2.0 at aa 10-32, 81-103, 113-132, 145-167, 187-209, 216-234 and 244-266 272560015172 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 70.4, E-value 2.4e-18 272560015173 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560015174 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560015175 dimer interface [polypeptide binding]; other site 272560015176 conserved gate region; other site 272560015177 putative PBP binding loops; other site 272560015178 ABC-ATPase subunit interface; other site 272560015179 6 probable transmembrane helices predicted for BPSL3165 by TMHMM2.0 at aa 38-60, 100-122, 135-155, 170-192, 231-253 and 291-313 272560015180 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 68.2, E-value 1.2e-17 272560015181 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560015182 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560015183 Signal peptide predicted for BPSL3166 by SignalP 2.0 HMM (Signal peptide probabilty 0.932) with cleavage site probability 0.703 between residues 43 and 44; signal peptide 272560015184 glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974 272560015185 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 219.3, E-value 3.8e-63 272560015186 PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 272560015187 deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286 272560015188 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560015189 Zn2+ binding site [ion binding]; other site 272560015190 Mg2+ binding site [ion binding]; other site 272560015191 Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286 272560015192 Pfam match to entry PF01966 HD, HD domain , score 65.0, E-value 1.1e-16 272560015193 Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195 272560015194 active site 272560015195 dimer interface [polypeptide binding]; other site 272560015196 metal binding site [ion binding]; metal-binding site 272560015197 Pfam match to entry PF01761 DHQ_synthase, 3-dehydroquinate synthase , score 592.4, E-value 1.8e-175 272560015198 Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703 272560015199 Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464 272560015200 ADP binding site [chemical binding]; other site 272560015201 magnesium binding site [ion binding]; other site 272560015202 putative shikimate binding site; other site 272560015203 Pfam match to entry PF01202 SKI, Shikimate kinase , score 209.5, E-value 3.2e-60 272560015204 PS01128 Shikimate kinase signature. 272560015205 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015206 type IV pilus secretin (or competence protein) PilQ; Region: IV_pilus_PilQ; TIGR02515 272560015207 Secretin and TonB N terminus short domain; Region: STN; smart00965 272560015208 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560015209 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560015210 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 269.9, E-value 2.1e-78 272560015211 1 probable transmembrane helix predicted for BPSL3172 by TMHMM2.0 at aa 40-62 272560015212 Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972 272560015213 Membrane carboxypeptidase/penicillin-binding protein [Cell envelope biogenesis, outer membrane]; Region: MrcA; COG5009 272560015214 Transglycosylase; Region: Transgly; pfam00912 272560015215 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560015216 1 probable transmembrane helix predicted for BPSL3174 by TMHMM2.0 at aa 28-50 272560015217 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 356.8, E-value 1.5e-104 272560015218 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 53.3, E-value 6.9e-14 272560015219 Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503 272560015220 putative iron binding site [ion binding]; other site 272560015221 Pfam match to entry PF01491 Frataxin_Cyay, Frataxin-like domain , score 129.6, E-value 3.6e-36 272560015222 Prokaryotic lipoprotein-attachment site; Region: LPAM_2; pfam13627 272560015223 diaminopimelate decarboxylase; Region: lysA; TIGR01048 272560015224 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828 272560015225 active site 272560015226 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560015227 substrate binding site [chemical binding]; other site 272560015228 catalytic residues [active] 272560015229 dimer interface [polypeptide binding]; other site 272560015230 Pfam match to entry PF02784 Orn_Arg_deC_N, Pyridoxal-dependent decarboxylase, pyridoxal binding domain , score 326.0, E-value 2.9e-95 272560015231 PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 272560015232 Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain , score 159.0, E-value 5.2e-45 272560015233 putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419 272560015234 6 probable transmembrane helices predicted for BPSL3177 by TMHMM2.0 at aa 37-59, 79-98, 111-128, 148-170, 183-200 and 210-227 272560015235 Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041 272560015236 YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107 272560015237 Moco binding site; other site 272560015238 metal coordination site [ion binding]; other site 272560015239 cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144 272560015240 11 probable transmembrane helices predicted for BPSL3179 by TMHMM2.0 at aa 34-56, 60-78, 85-102, 122-144, 156-175, 190-209, 216-238, 258-280, 301-323, 338-357 and 364-386 272560015241 Pfam match to entry PF01578 CytC_asm, Cytochrome C assembly protein , score 68.7, E-value 8.1e-18 272560015242 ResB-like family; Region: ResB; pfam05140 272560015243 Signal peptide predicted for BPSL3180 by SignalP 2.0 HMM (Signal peptide probabilty 0.926) with cleavage site probability 0.907 between residues 41 and 42; signal peptide 272560015244 4 probable transmembrane helices predicted for BPSL3180 by TMHMM2.0 at aa 20-42, 69-91, 167-189 and 636-654 272560015245 Cytochrome c553 [Energy production and conversion]; Region: COG2863 272560015246 Cytochrome c; Region: Cytochrom_C; cl11414 272560015247 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 7.3, E-value 0.0049 272560015248 PS00190 Cytochrome c family heme-binding site signature. 272560015249 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 50.8, E-value 2e-12 272560015250 PS00190 Cytochrome c family heme-binding site signature. 272560015251 Predicted GTPase [General function prediction only]; Region: COG0218 272560015252 YihA (EngB) GTPase family; Region: YihA_EngB; cd01876 272560015253 G1 box; other site 272560015254 GTP/Mg2+ binding site [chemical binding]; other site 272560015255 Switch I region; other site 272560015256 G2 box; other site 272560015257 G3 box; other site 272560015258 Switch II region; other site 272560015259 G4 box; other site 272560015260 G5 box; other site 272560015261 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015262 Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823 272560015263 dimer interface [polypeptide binding]; other site 272560015264 allosteric magnesium binding site [ion binding]; other site 272560015265 active site 272560015266 aspartate-rich active site metal binding site; other site 272560015267 Schiff base residues; other site 272560015268 Pfam match to entry PF00490 ALAD, Delta-aminolevulinic acid dehydratase , score 668.5, E-value 2.3e-198 272560015269 PS00169 Delta-aminolevulinic acid dehydratase active site. 272560015270 Signal peptide predicted for BPSL3184 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.846 between residues 35 and 36; signal peptide 272560015271 thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293 272560015272 Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412 272560015273 Sulfite exporter TauE/SafE; Region: TauE; cl19196 272560015274 DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953 272560015275 DsbD alpha interface [polypeptide binding]; other site 272560015276 catalytic residues [active] 272560015277 PS00194 Thioredoxin family active site. 272560015278 Pfam match to entry PF00085 thiored, Thioredoxin , score 17.1, E-value 5.5e-05 272560015279 9 probable transmembrane helices predicted for BPSL3184 by TMHMM2.0 at aa 13-35, 197-231, 244-266, 276-298, 331-353, 363-385, 398-417, 422-439 and 452-474 272560015280 Pfam match to entry PF02683 DsbD, Cytochrome C biogenesis protein transmembrane region , score 12.9, E-value 8.5e-07 272560015281 Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324 272560015282 Pfam match to entry PF03091 CutA1, CutA1 divalent ion tolerance protein , score 71.3, E-value 1.3e-18 272560015283 50S ribosomal protein L17; Validated; Region: rplQ; PRK05591 272560015284 Pfam match to entry PF01196 Ribosomal_L17, Ribosomal protein L17 , score 187.8, E-value 1.1e-53 272560015285 PS01167 Ribosomal protein L17 signature. 272560015286 DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182 272560015287 N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928 272560015288 alphaNTD homodimer interface [polypeptide binding]; other site 272560015289 alphaNTD - beta interaction site [polypeptide binding]; other site 272560015290 alphaNTD - beta' interaction site [polypeptide binding]; other site 272560015291 Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118 272560015292 Pfam match to entry PF03118 RNA_pol_A_CTD, Bacterial RNA polymerase, alpha chain C terminal domain , score 102.8, E-value 4.4e-28 272560015293 Pfam match to entry PF01000 RNA_pol_A_bac, Bacterial RNA polymerase, alpha chain, N terminal domain , score 338.3, E-value 5.6e-99 272560015294 30S ribosomal protein S4; Validated; Region: rpsD; PRK05327 272560015295 Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163 272560015296 S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site; Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165 272560015297 RNA binding surface [nucleotide binding]; other site 272560015298 Pfam match to entry PF01479 S4, S4 domain , score 83.6, E-value 2.7e-22 272560015299 PS00632 Ribosomal protein S4 signature. 272560015300 Pfam match to entry PF00163 Ribosomal_S4, Ribosomal protein S4/S9 N-terminal domain , score 116.2, E-value 4.1e-32 272560015301 30S ribosomal protein S11; Validated; Region: PRK05309 272560015302 Pfam match to entry PF00411 Ribosomal_S11, Ribosomal protein S11 , score 244.8, E-value 7.6e-71 272560015303 PS00054 Ribosomal protein S11 signature. 272560015304 30S ribosomal protein S13; Validated; Region: rpsM; PRK05179 272560015305 Pfam match to entry PF00416 Ribosomal_S13, Ribosomal protein S13/S18 , score 189.5, E-value 3.4e-54 272560015306 PS00646 Ribosomal protein S13 signature. 272560015307 Ribosomal protein L36; Region: Ribosomal_L36; pfam00444 272560015308 Pfam match to entry PF00444 Ribosomal_L36, Ribosomal protein L36 , score 62.6, E-value 5.5e-16 272560015309 PS00828 Ribosomal protein L36 signature. 272560015310 S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451 272560015311 rRNA binding site [nucleotide binding]; other site 272560015312 predicted 30S ribosome binding site; other site 272560015313 Pfam match to entry PF00575 S1, S1 RNA binding domain , score 38.6, E-value 9.5e-09 272560015314 preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204 272560015315 SecY translocase; Region: SecY; pfam00344 272560015316 Pfam match to entry PF00344 secY, eubacterial secY protein , score 563.4, E-value 9.8e-167 272560015317 10 probable transmembrane helices predicted for BPSL3193 by TMHMM2.0 at aa 32-51, 82-104, 125-147, 157-179, 186-208, 218-240, 276-298, 324-346, 377-399 and 404-426 272560015318 PS00756 Protein secY signature 2. 272560015319 PS00755 Protein secY signature 1. 272560015320 50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592 272560015321 Pfam match to entry PF00256 L15, Ribosomal protein L15 , score 36.8, E-value 3.2e-08 272560015322 PS00475 Ribosomal protein L15 signature. 272560015323 Pfam match to entry PF01305 Ribosomal_L15, Ribosomal protein L15 amino terminal region , score 169.8, E-value 3e-48 272560015324 Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658 272560015325 23S rRNA binding site [nucleotide binding]; other site 272560015326 Pfam match to entry PF00327 Ribosomal_L30, Ribosomal protein L30p/L7e , score 55.1, E-value 9.7e-14 272560015327 30S ribosomal protein S5; Validated; Region: rpsE; PRK00550 272560015328 Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333 272560015329 Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719 272560015330 Pfam match to entry PF03719 Ribosomal_S5_C, Ribosomal protein S5, C-terminal domain , score 109.5, E-value 4.1e-30 272560015331 Pfam match to entry PF00333 Ribosomal_S5, Ribosomal protein S5, N-terminal domain , score 115.4, E-value 6.8e-32 272560015332 PS00585 Ribosomal protein S5 signature. 272560015333 Ribosomal L18/L5e: L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432 272560015334 5S rRNA interface [nucleotide binding]; other site 272560015335 L27 interface [polypeptide binding]; other site 272560015336 23S rRNA interface [nucleotide binding]; other site 272560015337 L5 interface [polypeptide binding]; other site 272560015338 Pfam match to entry PF00861 Ribosomal_L18p, Ribosomal L18p/L5e family , score 138.3, E-value 8.7e-39 272560015339 50S ribosomal protein L6; Validated; Region: rplF; PRK05498 272560015340 Ribosomal protein L6; Region: Ribosomal_L6; pfam00347 272560015341 Pfam match to entry PF00347 Ribosomal_L6, Ribosomal protein L6 , score 119.8, E-value 3.3e-33 272560015342 PS00525 Ribosomal protein L6 signature 1. 272560015343 Pfam match to entry PF00347 Ribosomal_L6, Ribosomal protein L6 , score 53.3, E-value 3.5e-13 272560015344 30S ribosomal protein S8; Validated; Region: rpsH; PRK00136 272560015345 Pfam match to entry PF00410 Ribosomal_S8, Ribosomal protein S8 , score 231.9, E-value 5.9e-67 272560015346 PS00053 Ribosomal protein S8 signature. 272560015347 30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881 272560015348 Pfam match to entry PF00253 Ribosomal_S14, Ribosomal protein S14p/S29e , score 151.4, E-value 1e-42 272560015349 50S ribosomal protein L5; Validated; Region: rplE; PRK00010 272560015350 Ribosomal protein L5; Region: Ribosomal_L5; pfam00281 272560015351 ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673 272560015352 Pfam match to entry PF00673 Ribosomal_L5_C, ribosomal L5P family C-terminus , score 176.5, E-value 2.8e-50 272560015353 Pfam match to entry PF00281 Ribosomal_L5, Ribosomal protein L5 , score 113.6, E-value 2.5e-31 272560015354 PS00358 Ribosomal protein L5 signature. 272560015355 KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089 272560015356 RNA binding site [nucleotide binding]; other site 272560015357 Pfam match to entry PF00467 KOW, KOW motif , score 32.0, E-value 8.9e-07 272560015358 PS01108 Ribosomal protein L24 signature. 272560015359 50S ribosomal protein L14; Validated; Region: rplN; PRK05483 272560015360 Pfam match to entry PF00238 Ribosomal_L14, Ribosomal protein L14p/L23e , score 263.6, E-value 1.7e-76 272560015361 PS00049 Ribosomal protein L14 signature. 272560015362 30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610 272560015363 Pfam match to entry PF00366 Ribosomal_S17, Ribosomal protein S17 , score 128.2, E-value 1e-35 272560015364 PS00056 Ribosomal protein S17 signature. 272560015365 Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427 272560015366 23S rRNA interface [nucleotide binding]; other site 272560015367 putative translocon interaction site; other site 272560015368 signal recognition particle (SRP54) interaction site; other site 272560015369 L23 interface [polypeptide binding]; other site 272560015370 trigger factor interaction site; other site 272560015371 Pfam match to entry PF00831 Ribosomal_L29, Ribosomal L29 protein , score 58.5, E-value 9.1e-15 272560015372 PS00579 Ribosomal protein L29 signature. 272560015373 Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433 272560015374 23S rRNA interface [nucleotide binding]; other site 272560015375 5S rRNA interface [nucleotide binding]; other site 272560015376 putative antibiotic binding site [chemical binding]; other site 272560015377 L25 interface [polypeptide binding]; other site 272560015378 L27 interface [polypeptide binding]; other site 272560015379 Pfam match to entry PF00252 Ribosomal_L16, Ribosomal protein L16 , score 303.4, E-value 1.8e-88 272560015380 PS00586 Ribosomal protein L16 signature 1. 272560015381 30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310 272560015382 K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3 is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH...; Region: 30S_S3_KH; cd02412 272560015383 G-X-X-G motif; other site 272560015384 Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189 272560015385 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015386 Pfam match to entry PF00189 Ribosomal_S3_C, Ribosomal protein S3, C-terminal domain , score 183.2, E-value 2.7e-52 272560015387 PS00548 Ribosomal protein S3 signature. 272560015388 Pfam match to entry PF00013 KH, KH domain , score 39.4, E-value 5.2e-09 272560015389 Pfam match to entry PF00417 Ribosomal_S3_N, Ribosomal protein S3, N-terminal domain , score 99.0, E-value 6.3e-27 272560015390 Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336 272560015391 putative translocon binding site; other site 272560015392 protein-rRNA interface [nucleotide binding]; other site 272560015393 Pfam match to entry PF00237 Ribosomal_L22, Ribosomal protein L22p/L17e , score 159.0, E-value 5.1e-45 272560015394 PS00464 Ribosomal protein L22 signature. 272560015395 30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357 272560015396 Pfam match to entry PF00203 Ribosomal_S19, Ribosomal protein S19 , score 183.7, E-value 1.9e-52 272560015397 PS00323 Ribosomal protein S19 signature. 272560015398 50S ribosomal protein L2; Validated; Region: rplB; PRK09374 272560015399 Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181 272560015400 Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947 272560015401 Pfam match to entry PF03947 Ribosomal_L2_C, Ribosomal Proteins L2, C-terminal domain , score 290.3, E-value 1.6e-84 272560015402 PS00467 Ribosomal protein L2 signature. 272560015403 Pfam match to entry PF00181 Ribosomal_L2, Ribosomal Proteins L2, RNA binding domain , score 162.4, E-value 4.9e-46 272560015404 50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738 272560015405 Pfam match to entry PF00276 Ribosomal_L23, Ribosomal protein L23 , score 103.0, E-value 3.8e-28 272560015406 50S ribosomal protein L4; Provisional; Region: rplD; PRK05319 272560015407 Pfam match to entry PF00573 Ribosomal_L4, Ribosomal protein L4/L1 family , score 165.4, E-value 6.2e-47 272560015408 50S ribosomal protein L3; Validated; Region: rplC; PRK00001 272560015409 Pfam match to entry PF00297 Ribosomal_L3, Ribosomal protein L3 , score 275.2, E-value 5.6e-80 272560015410 PS00474 Ribosomal protein L3 signature. 272560015411 30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596 272560015412 Pfam match to entry PF00338 Ribosomal_S10, Ribosomal protein S10p/S20e , score 185.8, E-value 4.5e-53 272560015413 PS00361 Ribosomal protein S10 signature. 272560015414 elongation factor Tu; Reviewed; Region: PRK00049 272560015415 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 272560015416 G1 box; other site 272560015417 GEF interaction site [polypeptide binding]; other site 272560015418 GTP/Mg2+ binding site [chemical binding]; other site 272560015419 Switch I region; other site 272560015420 G2 box; other site 272560015421 G3 box; other site 272560015422 Switch II region; other site 272560015423 G4 box; other site 272560015424 G5 box; other site 272560015425 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 272560015426 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 272560015427 Antibiotic Binding Site [chemical binding]; other site 272560015428 Pfam match to entry PF03143 GTP_EFTU_D3, Elongation factor Tu C-terminal domain , score 219.8, E-value 2.6e-63 272560015429 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 109.2, E-value 5.3e-30 272560015430 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 343.4, E-value 1.6e-100 272560015431 PS00301 GTP-binding elongation factors signature. 272560015432 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015433 elongation factor G; Reviewed; Region: PRK00007 272560015434 Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886 272560015435 G1 box; other site 272560015436 putative GEF interaction site [polypeptide binding]; other site 272560015437 GTP/Mg2+ binding site [chemical binding]; other site 272560015438 Switch I region; other site 272560015439 G2 box; other site 272560015440 G3 box; other site 272560015441 Switch II region; other site 272560015442 G4 box; other site 272560015443 G5 box; other site 272560015444 EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088 272560015445 Elongation Factor G, domain II; Region: EFG_II; pfam14492 272560015446 EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434 272560015447 EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G. Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713 272560015448 Pfam match to entry PF00679 EFG_C, Elongation factor G C-terminus , score 176.1, E-value 3.8e-50 272560015449 Pfam match to entry PF03764 EFG_IV, Elongation factor G, domain IV , score 242.6, E-value 3.5e-70 272560015450 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 96.2, E-value 4.3e-26 272560015451 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 373.0, E-value 2e-109 272560015452 PS00301 GTP-binding elongation factors signature. 272560015453 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015454 30S ribosomal protein S7; Validated; Region: PRK05302 272560015455 Pfam match to entry PF00177 Ribosomal_S7, Ribosomal protein S7p/S5e , score 304.3, E-value 9.8e-89 272560015456 PS00052 Ribosomal protein S7 signature. 272560015457 S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368 272560015458 S17 interaction site [polypeptide binding]; other site 272560015459 S8 interaction site; other site 272560015460 16S rRNA interaction site [nucleotide binding]; other site 272560015461 streptomycin interaction site [chemical binding]; other site 272560015462 23S rRNA interaction site [nucleotide binding]; other site 272560015463 aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site 272560015464 Pfam match to entry PF00164 Ribosomal_S12, Ribosomal protein S12 , score 198.3, E-value 7.8e-57 272560015465 PS00055 Ribosomal protein S12 signature. 272560015466 ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389 272560015467 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560015468 ATP binding site [chemical binding]; other site 272560015469 putative Mg++ binding site [ion binding]; other site 272560015470 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560015471 nucleotide binding region [chemical binding]; other site 272560015472 ATP-binding site [chemical binding]; other site 272560015473 RQC domain; Region: RQC; pfam09382 272560015474 HRDC domain; Region: HRDC; pfam00570 272560015475 Pfam match to entry PF00570 HRDC, HRDC domain , score 80.0, E-value 3.1e-21 272560015476 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 92.9, E-value 4.3e-25 272560015477 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 120.8, E-value 1.6e-33 272560015478 DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566 272560015479 Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609 272560015480 beta and beta' interface [polypeptide binding]; other site 272560015481 beta' and sigma factor interface [polypeptide binding]; other site 272560015482 Zn-binding [ion binding]; other site 272560015483 active site region [active] 272560015484 catalytic site [active] 272560015485 Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655 272560015486 Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site 272560015487 Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site 272560015488 G-loop; other site 272560015489 DNA binding site [nucleotide binding] 272560015490 Pfam match to entry PF01854 RNA_pol_A2, RNA polymerase A/beta'/A subunit , score 40.9, E-value 5.1e-12 272560015491 Pfam match to entry PF01854 RNA_pol_A2, RNA polymerase A/beta'/A subunit , score 43.0, E-value 1.3e-12 272560015492 Pfam match to entry PF00623 RNA_pol_A, RNA polymerase alpha subunit , score 926.4, E-value 5.2e-276 272560015493 DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405 272560015494 RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653 272560015495 RPB12 interaction site [polypeptide binding]; other site 272560015496 RPB1 interaction site [polypeptide binding]; other site 272560015497 RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385 272560015498 RPB10 interaction site [polypeptide binding]; other site 272560015499 RPB11 interaction site [polypeptide binding]; other site 272560015500 RPB3 interaction site [polypeptide binding]; other site 272560015501 Pfam match to entry PF00562 RNA_pol_B, RNA polymerase beta subunit , score 2028.4, E-value 0 272560015502 PS01166 RNA polymerases beta chain signature. 272560015503 Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387 272560015504 Signal peptide predicted for BPSL3222 by SignalP 2.0 HMM (Signal peptide probabilty 0.851) with cleavage site probability 0.458 between residues 37 and 38; signal peptide 272560015505 core dimer interface [polypeptide binding]; other site 272560015506 L10 interface [polypeptide binding]; other site 272560015507 L11 interface [polypeptide binding]; other site 272560015508 putative EF-Tu interaction site [polypeptide binding]; other site 272560015509 putative EF-G interaction site [polypeptide binding]; other site 272560015510 Pfam match to entry PF00542 Ribosomal_L12, Ribosomal protein L7/L12 C-terminal domain , score 136.5, E-value 3.1e-38 272560015511 Pfam match to entry PF00428 60s_ribosomal, 60s Acidic ribosomal protein , score 19.2, E-value 1.4e-05 272560015512 Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797 272560015513 23S rRNA interface [nucleotide binding]; other site 272560015514 Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site 272560015515 Pfam match to entry PF00466 Ribosomal_L10, Ribosomal protein L10 , score 79.7, E-value 3.9e-21 272560015516 Ribosomal protein L1. The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA. In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403 272560015517 mRNA/rRNA interface [nucleotide binding]; other site 272560015518 Pfam match to entry PF00687 Ribosomal_L1, Ribosomal protein L1p/L10e family , score 401.7, E-value 4.7e-118 272560015519 PS01199 Ribosomal protein L1 signature. 272560015520 50S ribosomal protein L11; Validated; Region: rplK; PRK00140 272560015521 Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349 272560015522 23S rRNA interface [nucleotide binding]; other site 272560015523 L7/L12 interface [polypeptide binding]; other site 272560015524 putative thiostrepton binding site; other site 272560015525 L25 interface [polypeptide binding]; other site 272560015526 PS00359 Ribosomal protein L11 signature. 272560015527 Pfam match to entry PF00298 Ribosomal_L11, Ribosomal protein L11, RNA binding domain , score 128.4, E-value 8.6e-36 272560015528 Pfam match to entry PF03946 Ribosomal_L11_N, Ribosomal protein L11, N-terminal domain , score 128.5, E-value 8.1e-36 272560015529 transcription antitermination protein NusG; Validated; Region: nusG; PRK05609 272560015530 Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891 272560015531 putative homodimer interface [polypeptide binding]; other site 272560015532 NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091 272560015533 heterodimer interface [polypeptide binding]; other site 272560015534 homodimer interface [polypeptide binding]; other site 272560015535 PS01014 Transcription termination factor nusG signature. 272560015536 Pfam match to entry PF00467 KOW, KOW motif , score 42.9, E-value 4.7e-10 272560015537 Pfam match to entry PF02357 NusG, Transcription termination factor nusG , score 71.4, E-value 1.2e-18 272560015538 preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740 272560015539 Pfam match to entry PF00584 SecE, SecE/Sec61-gamma subunits of protein translocation complex , score 61.8, E-value 9.5e-16 272560015540 3 probable transmembrane helices predicted for BPSL3227 by TMHMM2.0 at aa 15-37, 44-63 and 90-109 272560015541 elongation factor Tu; Reviewed; Region: PRK00049 272560015542 Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884 272560015543 G1 box; other site 272560015544 GEF interaction site [polypeptide binding]; other site 272560015545 GTP/Mg2+ binding site [chemical binding]; other site 272560015546 Switch I region; other site 272560015547 G2 box; other site 272560015548 G3 box; other site 272560015549 Switch II region; other site 272560015550 G4 box; other site 272560015551 G5 box; other site 272560015552 EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697 272560015553 Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707 272560015554 Antibiotic Binding Site [chemical binding]; other site 272560015555 Pfam match to entry PF03143 GTP_EFTU_D3, Elongation factor Tu C-terminal domain , score 219.8, E-value 2.6e-63 272560015556 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 109.2, E-value 5.3e-30 272560015557 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 343.4, E-value 1.6e-100 272560015558 PS00301 GTP-binding elongation factors signature. 272560015559 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015560 Signal peptide predicted for BPSL3229 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.714 between residues 24 and 25; signal peptide 272560015561 SGNH_hydrolase subfamily, similar to the putative arylesterase/acylhydrolase from the rumen anaerobe Prevotella bryantii XynE. The P. bryantii XynE gene is located in a xylanase gene cluster. SGNH hydrolases are a diverse family of lipases and esterases; Region: XynE_like; cd01830 272560015562 active site 272560015563 catalytic triad [active] 272560015564 oxyanion hole [active] 272560015565 phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778 272560015566 phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781 272560015567 Phenylacetic acid catabolic protein; Region: PaaA_PaaC; pfam05138 272560015568 Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151 272560015569 phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159 272560015570 Pfam match to entry PF01883 DUF59, Domain of unknown function DUF59 , score 65.6, E-value 6.7e-17 272560015571 phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160 272560015572 NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214 272560015573 FAD binding pocket [chemical binding]; other site 272560015574 FAD binding motif [chemical binding]; other site 272560015575 phosphate binding motif [ion binding]; other site 272560015576 beta-alpha-beta structure motif; other site 272560015577 NAD(p) ribose binding residues [chemical binding]; other site 272560015578 NAD binding pocket [chemical binding]; other site 272560015579 NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site 272560015580 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560015581 catalytic loop [active] 272560015582 iron binding site [ion binding]; other site 272560015583 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 62.1, E-value 8e-16 272560015584 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 36.5, E-value 4e-08 272560015585 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 76.6, E-value 3.4e-20 272560015586 Domain of unknown function (DUF1835); Region: DUF1835; pfam08874 272560015587 Protein of unknown function; Region: DUF3658; pfam12395 272560015588 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560015589 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560015590 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 44.8, E-value 1.2e-10 272560015591 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560015592 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560015593 Coenzyme A binding pocket [chemical binding]; other site 272560015594 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 37.5, E-value 1.9e-08 272560015595 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560015596 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560015597 putative DNA binding site [nucleotide binding]; other site 272560015598 putative Zn2+ binding site [ion binding]; other site 272560015599 AsnC family; Region: AsnC_trans_reg; pfam01037 272560015600 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 139.4, E-value 4.2e-39 272560015601 PS00519 Bacterial regulatory proteins, asnC family signature. 272560015602 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [Amino acid transport and metabolism / General function prediction only]; Region: COG3185 272560015603 N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342 272560015604 dimer interface [polypeptide binding]; other site 272560015605 C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250 272560015606 active site 272560015607 Fe binding site [ion binding]; other site 272560015608 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 27.7, E-value 1.8e-05 272560015609 Signal peptide predicted for BPSL3240 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.954 between residues 25 and 26; signal peptide 272560015610 indolepyruvate ferredoxin oxidoreductase; Validated; Region: PRK09193 272560015611 Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034 272560015612 dimer interface [polypeptide binding]; other site 272560015613 PYR/PP interface [polypeptide binding]; other site 272560015614 TPP binding site [chemical binding]; other site 272560015615 substrate binding site [chemical binding]; other site 272560015616 Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008 272560015617 TPP-binding site; other site 272560015618 Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558 272560015619 Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546 272560015620 Pfam match to entry PF01558 POR, Pyruvate ferredoxin/flavodoxin oxidoreductase , score -24.4, E-value 0.00018 272560015621 bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232 272560015622 Malic enzyme, N-terminal domain; Region: malic; pfam00390 272560015623 NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311 272560015624 putative NAD(P) binding site [chemical binding]; other site 272560015625 Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280 272560015626 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase , score 382.0, E-value 4e-112 272560015627 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560015628 Pfam match to entry PF03949 malic_N, Malic enzyme, NAD binding domain , score 427.4, E-value 8.5e-126 272560015629 Pfam match to entry PF00390 malic, Malic enzyme, N-terminal domain , score 269.9, E-value 2.2e-78 272560015630 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560015631 active site 272560015632 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 73.7, E-value 2.5e-19 272560015633 Signal peptide predicted for BPSL3244 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.965 between residues 37 and 38; signal peptide 272560015634 PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865 272560015635 substrate binding site [chemical binding]; other site 272560015636 Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655 272560015637 Pfam match to entry PF00258 flavodoxin, Flavodoxin , score 22.8, E-value 3e-05 272560015638 PS00201 Flavodoxin signature. 272560015639 N-acetyl-gamma-glutamyl-phosphate reductase; Provisional; Region: PRK11863 272560015640 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859 272560015641 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 272560015642 Signal peptide predicted for BPSL3248 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.219 between residues 22 and 23; signal peptide 272560015643 Protein of unknown function (DUF2957); Region: DUF2957; pfam11170 272560015644 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015645 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 272560015646 Signal peptide predicted for BPSL3249 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 between residues 21 and 22; signal peptide 272560015647 Pfam match to entry PF03922 OmpW, OmpW family , score 34.4, E-value 1e-08 272560015648 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560015649 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560015650 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560015651 dimerization interface [polypeptide binding]; other site 272560015652 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 116.5, E-value 3.3e-32 272560015653 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 94.6, E-value 1.3e-25 272560015654 PS00044 Bacterial regulatory proteins, lysR family signature. 272560015655 Signal peptide predicted for BPSL3251 by SignalP 2.0 HMM (Signal peptide probabilty 0.752) with cleavage site probability 0.631 between residues 16 and 17; signal peptide 272560015656 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560015657 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560015658 12 probable transmembrane helices predicted for BPSL3251 by TMHMM2.0 at aa 7-25, 35-57, 64-83, 88-110, 123-142, 152-174, 205-227, 237-256, 269-291, 295-317, 338-360 and 364-386 272560015659 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560015660 6 probable transmembrane helices predicted for BPSL3252 by TMHMM2.0 at aa 35-57, 78-100, 104-121, 162-184, 194-216 and 228-250 272560015661 Pfam match to entry PF01810 LysE, LysE type translocator , score 77.8, E-value 1.5e-20 272560015662 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 272560015663 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560015664 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560015665 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score 13.5, E-value 0.00033 272560015666 Mut7-C ubiquitin; Region: Ub-Mut7C; pfam14451 272560015667 Mut7-C RNAse domain; Region: Mut7-C; pfam01927 272560015668 Pfam match to entry PF01927 DUF82, Protein of unknown function DUF82 , score 129.4, E-value 4.2e-36 272560015669 RNAse P Rpr2/Rpp21/SNM1 subunit domain; Region: Rpr2; cl00887 272560015670 3 probable transmembrane helices predicted for BPSL3255 by TMHMM2.0 at aa 10-32, 44-63 and 78-100 272560015671 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 272560015672 Spore germination protein; Region: Spore_permease; cl17796 272560015673 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 602.2, E-value 2.1e-178 272560015674 12 probable transmembrane helices predicted for BPSL3256 by TMHMM2.0 at aa 21-40, 44-66, 99-121, 126-145, 157-179, 199-221, 242-264, 284-306, 338-355, 359-381, 403-425 and 430-449 272560015675 PS00218 Amino acid permeases signature. 272560015676 Genomic island GI 11; integrated plasmid 272560015677 Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582 272560015678 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560015679 active site 272560015680 DNA binding site [nucleotide binding] 272560015681 Int/Topo IB signature motif; other site 272560015682 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 88.7, E-value 7.6e-24 272560015683 AAA domain; Region: AAA_13; pfam13166 272560015684 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560015685 Walker B; other site 272560015686 D-loop; other site 272560015687 H-loop/switch region; other site 272560015688 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015689 Pfam match to entry PF02370 M, M protein repeat , score 8.4, E-value 3.4 272560015690 Pfam match to entry PF02370 M, M protein repeat , score 0.0, E-value 48 272560015691 Pfam match to entry PF02370 M, M protein repeat , score 2.6, E-value 21 272560015692 Pfam match to entry PF02370 M, M protein repeat , score 8.6, E-value 3.2 272560015693 hypothetical protein; Provisional; Region: PRK08999 272560015694 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200 272560015695 Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877 272560015696 Toxin of toxin-antitoxin type 1 system; Region: plasmid_Toxin; pfam12703 272560015697 TrbL/VirB6 plasmid conjugal transfer protein; Region: TrbL; cl01503 272560015698 7 probable transmembrane helices predicted for BPSL3262 by TMHMM2.0 at aa 62-81, 101-123, 144-166, 212-234, 236-258, 268-290 and 327-349 272560015699 Signal peptide predicted for BPSL3263 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 1.000 between residues 27 and 28; signal peptide 272560015700 conjugal transfer protein TrbJ; Provisional; Region: PRK13879 272560015701 conjugal transfer relaxase TraI; Provisional; Region: PRK13878 272560015702 Pfam match to entry PF03432 Relaxase, Relaxase/Mobilization nuclease domain , score 241.5, E-value 7.9e-70 272560015703 conjugal transfer relaxosome component TraJ; Provisional; Region: PRK13877 272560015704 degenerin; Region: deg-1; TIGR00867 272560015705 2 probable transmembrane helices predicted for BPSL3268 by TMHMM2.0 at aa 82-101 and 106-125 272560015706 Plasmid encoded RepA protein; Region: RepA_C; pfam04796 272560015707 Signal peptide predicted for BPSL3271 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.978 between residues 33 and 34; signal peptide 272560015708 Cytochrome c; Region: Cytochrom_C; cl11414 272560015709 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 37.1, E-value 2.5e-08 272560015710 PS00190 Cytochrome c family heme-binding site signature. 272560015711 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015712 Signal peptide predicted for BPSL3272 by SignalP 2.0 HMM (Signal peptide probabilty 0.998) with cleavage site probability 0.247 between residues 35 and 36; signal peptide 272560015713 Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823 272560015714 BON domain; Region: BON; pfam04972 272560015715 BON domain; Region: BON; pfam04972 272560015716 1 probable transmembrane helix predicted for BPSL3272 by TMHMM2.0 at aa 13-35 272560015717 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015718 Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006 272560015719 dimer interface [polypeptide binding]; other site 272560015720 active site 272560015721 Pfam match to entry PF01380 SIS, SIS domain , score 32.1, E-value 8.6e-07 272560015722 hypothetical protein; Provisional; Region: PRK14673 272560015723 Pfam match to entry PF02021 UPF0102, Uncharacterised protein family UPF0102 , score 89.8, E-value 3.5e-24 272560015724 Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648 272560015725 putative SAM binding site [chemical binding]; other site 272560015726 putative homodimer interface [polypeptide binding]; other site 272560015727 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 141.4, E-value 1.1e-39 272560015728 PS01296 Uncharacterized protein family UPF0011 signature. 272560015729 Signal peptide predicted for BPSL3276 by SignalP 2.0 HMM (Signal peptide probabilty 0.991) with cleavage site probability 0.281 between residues 27 and 28; signal peptide 272560015730 Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797 272560015731 Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330 272560015732 Pfam match to entry PF03330 Lipoprotein_13, Rare lipoprotein A (RlpA) family , score 216.6, E-value 2.5e-62 272560015733 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015734 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 272560015735 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 161.5, E-value 9.1e-46 272560015736 active site 272560015737 catalytic site [active] 272560015738 substrate binding site [chemical binding]; other site 272560015739 DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012 272560015740 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560015741 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560015742 putative DNA binding site [nucleotide binding]; other site 272560015743 putative Zn2+ binding site [ion binding]; other site 272560015744 AsnC family; Region: AsnC_trans_reg; pfam01037 272560015745 PS00519 Bacterial regulatory proteins, asnC family signature. 272560015746 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 145.5, E-value 6e-41 272560015747 Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053 272560015748 Pfam match to entry PF01545 Cation_efflux, Cation efflux family , score 260.7, E-value 1.2e-75 272560015749 4 probable transmembrane helices predicted for BPSL3280 by TMHMM2.0 at aa 20-42, 90-109, 119-141 and 170-192 272560015750 H-NS histone family; Region: Histone_HNS; pfam00816 272560015751 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560015752 Pyridoxamine 5'-phosphate oxidase; Region: Pyrid_oxidase_2; pfam13883 272560015753 Pfam match to entry PF03774 DUF319, Protein of unknown function (DUF319) , score 35.7, E-value 1.2e-09 272560015754 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560015755 Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738 272560015756 putative substrate translocation pore; other site 272560015757 11 probable transmembrane helices predicted for BPSL3283 by TMHMM2.0 at aa 26-48, 55-77, 104-126, 153-175, 180-202, 223-242, 252-274, 286-308, 313-335, 348-370 and 375-397 272560015758 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560015759 dimerization interface [polypeptide binding]; other site 272560015760 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560015761 ligand binding site [chemical binding]; other site 272560015762 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 65.8, E-value 6.1e-17 272560015763 Signal peptide predicted for BPSL3284 by SignalP 2.0 HMM (Signal peptide probabilty 0.996) with cleavage site probability 0.678 between residues 44 and 45 272560015764 Nitronate monooxygenase; Region: NMO; pfam03060 272560015765 2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730 272560015766 FMN binding site [chemical binding]; other site 272560015767 substrate binding site [chemical binding]; other site 272560015768 putative catalytic residue [active] 272560015769 Pfam match to entry PF03060 NPD, 2-nitropropane dioxygenase , score 287.0, E-value 1.6e-83 272560015770 Dienelactone hydrolase family; Region: DLH; pfam01738 272560015771 Pfam match to entry PF01738 DLH, Dienelactone hydrolase , score 238.9, E-value 4.7e-69 272560015772 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cl18951 272560015773 Pfam match to entry PF01425 Amidase, Amidase , score 278.6, E-value 5.3e-81 272560015774 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015775 PS00571 Amidases signature. 272560015776 Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537 272560015777 FAD binding site [chemical binding]; other site 272560015778 Pfam match to entry PF02219 MTHFR, Methylenetetrahydrofolate reductase , score 360.1, E-value 1.5e-105 272560015779 Membrane protein of unknown function; Region: DUF360; pfam04020 272560015780 4 probable transmembrane helices predicted for BPSL3289 by TMHMM2.0 at aa 4-26, 33-55, 59-81 and 88-110 272560015781 S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476 272560015782 S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401 272560015783 homotetramer interface [polypeptide binding]; other site 272560015784 ligand binding site [chemical binding]; other site 272560015785 catalytic site [active] 272560015786 NAD binding site [chemical binding]; other site 272560015787 Pfam match to entry PF00670 AdoHcyase, S-adenosyl-L-homocysteine hydrolase , score 1090.3, E-value 0 272560015788 PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 272560015789 PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 272560015790 flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986 272560015791 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560015792 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 272560015793 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560015794 DNA binding residues [nucleotide binding] 272560015795 PS00716 Sigma-70 factors family signature 2. 272560015796 PS00715 Sigma-70 factors family signature 1. 272560015797 Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455 272560015798 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560015799 flagellar biosynthesis regulator FlhF; Provisional; Region: flhF; PRK14722 272560015800 SRP54-type protein, GTPase domain; Region: SRP54; smart00962 272560015801 Pfam match to entry PF00448 SRP54, SRP54-type protein, GTPase domain , score 83.7, E-value 2.5e-22 272560015802 PS00017 ATP/GTP-binding site motif A (P-loop). 272560015803 flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012 272560015804 Pfam match to entry PF00771 FHIPEP, FHIPEP family , score 1172.2, E-value 0 272560015805 7 probable transmembrane helices predicted for BPSL3294 by TMHMM2.0 at aa 20-39, 43-65, 77-99, 119-141, 210-232, 252-274 and 287-309 272560015806 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 272560015807 PS00994 Bacterial export FHIPEP family signature. 272560015808 flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702 272560015809 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family , score 457.8, E-value 5.9e-135 272560015810 4 probable transmembrane helices predicted for BPSL3295 by TMHMM2.0 at aa 36-58, 99-121, 150-169 and 189-211 272560015811 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 272560015812 dimer interface [polypeptide binding]; other site 272560015813 Signal peptide predicted for BPSL3297 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.605 between residues 26 and 27; signal peptide 272560015814 Protein of unknown function (DUF3443); Region: DUF3443; pfam11925 272560015815 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015816 Signal peptide predicted for BPSL3298 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.998 between residues 27 and 28; signal peptide 272560015817 Protein of unknown function (DUF2844); Region: DUF2844; pfam11005 272560015818 chemotaxis regulator CheZ; Provisional; Region: PRK11166 272560015819 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560015820 active site 272560015821 phosphorylation site [posttranslational modification] 272560015822 intermolecular recognition site; other site 272560015823 dimerization interface [polypeptide binding]; other site 272560015824 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 151.9, E-value 7.4e-43 272560015825 chemotaxis-specific methylesterase; Provisional; Region: PRK00742 272560015826 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560015827 active site 272560015828 phosphorylation site [posttranslational modification] 272560015829 intermolecular recognition site; other site 272560015830 dimerization interface [polypeptide binding]; other site 272560015831 CheB methylesterase; Region: CheB_methylest; pfam01339 272560015832 Pfam match to entry PF01339 CheB_methylest, CheB methylesterase , score 376.2, E-value 2.2e-110 272560015833 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 117.0, E-value 2.3e-32 272560015834 chemoreceptor glutamine deamidase CheD; Provisional; Region: PRK13489 272560015835 Pfam match to entry PF03975 CheD, CheD , score 147.7, E-value 1.3e-41 272560015836 chemotaxis methyltransferase CheR; Provisional; Region: PRK10611 272560015837 CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705 272560015838 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560015839 Pfam match to entry PF01739 CheR, CheR methyltransferase, SAM binding domain , score 257.0, E-value 1.6e-74 272560015840 Pfam match to entry PF03705 CheR_N, CheR methyltransferase, all-alpha domain , score 63.1, E-value 3.9e-16 272560015841 methyl-accepting protein IV; Provisional; Region: PRK09793 272560015842 Signal peptide predicted for BPSL3304 by SignalP 2.0 HMM (Signal peptide probabilty 0.983) with cleavage site probability 0.364 between residues 34 and 35; signal peptide 272560015843 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 272560015844 dimer interface [polypeptide binding]; other site 272560015845 ligand binding site [chemical binding]; other site 272560015846 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560015847 dimerization interface [polypeptide binding]; other site 272560015848 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560015849 dimer interface [polypeptide binding]; other site 272560015850 putative CheW interface [polypeptide binding]; other site 272560015851 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 353.0, E-value 2e-103 272560015852 Pfam match to entry PF00672 HAMP, HAMP domain , score 42.2, E-value 7.5e-10 272560015853 2 probable transmembrane helices predicted for BPSL3304 by TMHMM2.0 at aa 10-32 and 190-212 272560015854 CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732 272560015855 putative CheA interaction surface; other site 272560015856 Pfam match to entry PF01584 CheW, CheW-like domain , score 206.5, E-value 2.7e-59 272560015857 chemotaxis protein CheA; Provisional; Region: PRK10547 272560015858 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 272560015859 putative binding surface; other site 272560015860 active site 272560015861 CheY binding; Region: CheY-binding; pfam09078 272560015862 Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895 272560015863 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560015864 ATP binding site [chemical binding]; other site 272560015865 Mg2+ binding site [ion binding]; other site 272560015866 G-X-G motif; other site 272560015867 CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731 272560015868 Pfam match to entry PF01584 CheW, CheW-like domain , score 100.8, E-value 1.8e-27 272560015869 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 99.3, E-value 4.9e-27 272560015870 Pfam match to entry PF02895 H-kinase_dim, Signal transducing histidine kinase, homodimeric domain , score 85.5, E-value 7.1e-23 272560015871 Pfam match to entry PF01627 Hpt, Hpt domain , score 134.6, E-value 1.2e-37 272560015872 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560015873 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560015874 active site 272560015875 phosphorylation site [posttranslational modification] 272560015876 intermolecular recognition site; other site 272560015877 dimerization interface [polypeptide binding]; other site 272560015878 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 88.1, E-value 1.2e-23 272560015879 flagellar motor protein MotB; Validated; Region: motB; PRK09041 272560015880 Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677 272560015881 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560015882 ligand binding site [chemical binding]; other site 272560015883 Pfam match to entry PF00691 OmpA, OmpA family , score 96.5, E-value 3.5e-26 272560015884 1 probable transmembrane helix predicted for BPSL3308 by TMHMM2.0 at aa 28-50 272560015885 flagellar motor protein MotA; Validated; Region: PRK09110 272560015886 Signal peptide predicted for BPSL3309 by SignalP 2.0 HMM (Signal peptide probabilty 0.989) with cleavage site probability 0.967 between residues 21 and 22; signal peptide 272560015887 4 probable transmembrane helices predicted for BPSL3309 by TMHMM2.0 at aa 2-24, 34-51, 171-190 and 205-227 272560015888 PS01307 Flagellar motor protein motA family signature. 272560015889 transcriptional activator FlhC; Provisional; Region: PRK12722 272560015890 transcriptional activator FlhD; Provisional; Region: PRK02909 272560015891 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560015892 This family is most closely related to the GT1 family of glycosyltransferases. aviGT4 in Streptomyces viridochromogenes has been shown to be involved in biosynthesis of oligosaccharide antibiotic avilamycin A. Inactivation of aviGT4 resulted in a mutant...; Region: GT1_AviGT4_like; cd03802 272560015893 putative ADP-binding pocket [chemical binding]; other site 272560015894 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 94.2, E-value 1.7e-25 272560015895 H-NS histone family; Region: Histone_HNS; pfam00816 272560015896 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560015897 Signal peptide predicted for BPSL3314 by SignalP 2.0 HMM (Signal peptide probabilty 0.974) with cleavage site probability 0.630 between residues 28 and 29; signal peptide 272560015898 Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333 272560015899 amphipathic channel; other site 272560015900 Asn-Pro-Ala signature motifs; other site 272560015901 Pfam match to entry PF00230 MIP, Major intrinsic protein , score 148.0, E-value 1.1e-41 272560015902 6 probable transmembrane helices predicted for BPSL3314 by TMHMM2.0 at aa 7-29, 34-56, 83-105, 131-153, 160-182 and 207-229 272560015903 PS00221 MIP family signature. 272560015904 putative hydrolase; Provisional; Region: PRK10976 272560015905 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560015906 haloacid dehalogenase-like hydrolase; Region: HAD; cl19137 272560015907 active site 272560015908 motif I; other site 272560015909 motif II; other site 272560015910 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 47.7, E-value 1.7e-11 272560015911 PS01229 Hypothetical cof family signature 2. 272560015912 PS01228 Hypothetical cof family signature 1. 272560015913 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 272560015914 Methyladenine glycosylase; Region: Adenine_glyco; pfam03352 272560015915 Pfam match to entry PF03352 Adenine_glyco, Methyladenine glycosylase , score 329.4, E-value 2.7e-96 272560015916 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 272560015917 Pfam match to entry PF01165 Ribosomal_S21, Ribosomal protein S21 , score 116.6, E-value 3e-32 272560015918 flagellin; Reviewed; Region: PRK08869 272560015919 Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669 272560015920 Flagellin structural protein; Region: FliC_SP; pfam12613 272560015921 Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700 272560015922 Pfam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus , score 209.3, E-value 3.8e-60 272560015923 Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus , score 63.5, E-value 3e-16 272560015924 Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465 272560015925 flagellar capping protein; Reviewed; Region: fliD; PRK08032 272560015926 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 272560015927 Pfam match to entry PF02465 FliD, Flagellar hook-associated protein 2 , score 183.9, E-value 1.7e-52 272560015928 Flagellar protein FliT; Region: FliT; pfam05400 272560015929 FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457 272560015930 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560015931 TPR motif; other site 272560015932 binding surface 272560015933 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560015934 binding surface 272560015935 TPR motif; other site 272560015936 Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones]; Region: Spy; COG3914 272560015937 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560015938 TPR motif; other site 272560015939 binding surface 272560015940 Glycosyl transferases group 1; Region: Glycos_transf_1; cl19138 272560015941 Pfam match to entry PF00515 TPR, TPR Domain , score 5.5, E-value 0.75 272560015942 Pfam match to entry PF00515 TPR, TPR Domain , score 13.3, E-value 0.11 272560015943 Pfam match to entry PF00515 TPR, TPR Domain , score 11.3, E-value 0.18 272560015944 Pfam match to entry PF00515 TPR, TPR Domain , score 15.5, E-value 0.063 272560015945 Pfam match to entry PF00515 TPR, TPR Domain , score 29.0, E-value 7.3e-06 272560015946 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 272560015947 inhibitor-cofactor binding pocket; inhibition site 272560015948 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560015949 catalytic residue [active] 272560015950 Pfam match to entry PF01041 DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase , score 377.4, E-value 9.7e-111 272560015951 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 272560015952 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 272560015953 dimer interface [polypeptide binding]; other site 272560015954 active site 272560015955 CoA binding pocket [chemical binding]; other site 272560015956 Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236 272560015957 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 272560015958 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352 272560015959 dimer interface [polypeptide binding]; other site 272560015960 active site 272560015961 CoA binding pocket [chemical binding]; other site 272560015962 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560015963 classical (c) SDRs; Region: SDR_c; cd05233 272560015964 NAD(P) binding site [chemical binding]; other site 272560015965 active site 272560015966 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 140.2, E-value 2.5e-39 272560015967 PS00061 Short-chain dehydrogenases/reductases family signature. 272560015968 Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360 272560015969 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570 272560015970 putative trimer interface [polypeptide binding]; other site 272560015971 putative CoA binding site [chemical binding]; other site 272560015972 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 9.9, E-value 2.6 272560015973 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 4.2, E-value 14 272560015974 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 0.9, E-value 36 272560015975 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 6.5, E-value 7.1 272560015976 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 17.0, E-value 0.029 272560015977 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 272560015978 [2Fe-2S] cluster binding site [ion binding]; other site 272560015979 C-terminal catalytic domain of the oxygenase alpha subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C; cd00680 272560015980 alpha subunit interface [polypeptide binding]; other site 272560015981 active site 272560015982 substrate binding site [chemical binding]; other site 272560015983 Fe binding site [ion binding]; other site 272560015984 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 73.5, E-value 2.9e-19 272560015985 Methyltransferase domain; Region: Methyltransf_23; pfam13489 272560015986 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560015987 5 probable transmembrane helices predicted for BPSL3332 by TMHMM2.0 at aa 7-29, 70-92, 113-135, 150-172 and 185-204 272560015988 Pfam match to entry PF01810 LysE, LysE type translocator , score 49.1, E-value 6.5e-12 272560015989 Phospholipase C [Cell envelope biogenesis, outer membrane]; Region: PlcC; COG3511 272560015990 acid phosphatase, Burkholderia-type; Region: acid_phos_Burk; TIGR03397 272560015991 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560015992 Signal peptide predicted for BPSL3334 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.699 between residues 27 and 28; signal peptide 272560015993 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4380 272560015994 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015995 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4259 272560015996 Signal peptide predicted for BPSL3335 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.624 between residues 26 and 27; signal peptide 272560015997 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560015998 Signal peptide predicted for BPSL3336 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.397 between residues 23 and 24; signal peptide 272560015999 Uncharacterized protein involved in formation of curli polymers [Cell envelope biogenesis, outer membrane]; Region: CsgG; COG1462 272560016000 Pfam match to entry PF03783 CsgG, Curli production assembly/transport component CsgG , score 207.8, E-value 1e-59 272560016001 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016002 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560016003 3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427 272560016004 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560016005 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 79.3, E-value 5.1e-21 272560016006 Cache domain; Region: Cache_1; pfam02743 272560016007 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560016008 dimerization interface [polypeptide binding]; other site 272560016009 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560016010 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560016011 dimer interface [polypeptide binding]; other site 272560016012 putative CheW interface [polypeptide binding]; other site 272560016013 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 352.1, E-value 4e-103 272560016014 Pfam match to entry PF00672 HAMP, HAMP domain , score 67.0, E-value 2.5e-17 272560016015 2 probable transmembrane helices predicted for BPSL3338 by TMHMM2.0 at aa 13-35 and 277-299 272560016016 Pfam match to entry PF02743 Cache, Cache domain , score 53.5, E-value 3.1e-13 272560016017 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560016018 FAD binding domain; Region: FAD_binding_4; cl19922 272560016019 Berberine and berberine like; Region: BBE; pfam08031 272560016020 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 64.8, E-value 1.2e-16 272560016021 Chitin binding domain; Region: Chitin_bind_3; pfam03067 272560016022 Pfam match to entry PF03067 Chitin_bind_3, Chitin binding domain , score -7.7, E-value 6.5e-08 272560016023 Signal peptide predicted for BPSL3341 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.901 between residues 23 and 24; signal peptide 272560016024 Genomic island GI 12; Possible prophage 272560016025 AAA domain; Region: AAA_23; pfam13476 272560016026 AAA ATPase domain; Region: AAA_15; pfam13175 272560016027 Walker A/P-loop; other site 272560016028 ATP binding site [chemical binding]; other site 272560016029 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267 272560016030 Walker B; other site 272560016031 D-loop; other site 272560016032 H-loop/switch region; other site 272560016033 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016034 Phage derived protein Gp49-like (DUF891); Region: Gp49; pfam05973 272560016035 Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974 272560016036 DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213 272560016037 active site 272560016038 DNA binding site [nucleotide binding] 272560016039 Int/Topo IB signature motif; other site 272560016040 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 130.7, E-value 1.7e-36 272560016041 Signal peptide predicted for BPSL3347 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.480 between residues 22 and 23; signal peptide 272560016042 pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519 272560016043 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560016044 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 96.1, E-value 4.4e-26 272560016045 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560016046 ATPases associated with a variety of cellular activities; Region: AAA; smart00382 272560016047 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560016048 Walker A motif; other site 272560016049 ATP binding site [chemical binding]; other site 272560016050 Walker B motif; other site 272560016051 arginine finger; other site 272560016052 1 probable transmembrane helix predicted for BPSL3348 by TMHMM2.0 at aa 264-286 272560016053 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016054 Signal peptide predicted for BPSL3349 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.992 between residues 33 and 34; signal peptide 272560016055 Neisseria meningitidis TspB protein; Region: Neisseria_TspB; pfam05616 272560016056 3 probable transmembrane helices predicted for BPSL3349 by TMHMM2.0 at aa 12-34, 92-114 and 558-575 272560016057 1 probable transmembrane helix predicted for BPSL3350 by TMHMM2.0 at aa 67-89 272560016058 Signal peptide predicted for BPSL3351 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.866 between residues 18 and 19; signal peptide 272560016059 2 probable transmembrane helices predicted for BPSL3351 by TMHMM2.0 at aa 5-22 and 37-59 272560016060 Weakly similar to the N-terminal region of Haemophilus influenzae HTH-type transcriptional regulator HI1476 SWALL:YE76_HAEIN (SWALL:P44207) (239 aa) fasta scores: E(): 0.8, 27.13% id in 129 aa. N-terminal region is similar to Streptomyces coelicolor transcriptional regulator sco5614 or sc2e1.31 SWALL:O69902 (EMBL:AL939124) (63 aa) fasta scores: E(): 8, 31.48% id in 54 aa. Possible gene remnant; DNA-binding protein (fragment) 272560016061 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 25.0, E-value 0.00011 272560016062 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560016063 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 272560016064 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560016065 Cytochrome c5 [Energy production and conversion]; Region: CycB; COG3245 272560016066 1 probable transmembrane helix predicted for BPSL3354 by TMHMM2.0 at aa 15-37 272560016067 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 23.6, E-value 0.00011 272560016068 PS00190 Cytochrome c family heme-binding site signature. 272560016069 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 30.0, E-value 3.6e-06 272560016070 PS00190 Cytochrome c family heme-binding site signature. 272560016071 ATP-dependent DNA helicase Rep; Region: rep; TIGR01074 272560016072 Part of AAA domain; Region: AAA_19; pfam13245 272560016073 UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538 272560016074 Pfam match to entry PF00580 UvrD-helicase, UvrD/REP helicase , score 626.7, E-value 8.5e-186 272560016075 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016076 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016077 6 probable transmembrane helices predicted for BPSL3356 by TMHMM2.0 at aa 15-34, 41-63, 73-95, 102-121, 182-204 and 217-239 272560016078 SGNH_hydrolase subfamily, FeeA, FeeB and similar esterases/lipases. FeeA and FeeB are part of a biosynthetic gene cluster and may participate in the biosynthesis of long-chain N-acyltyrosines by providing saturated and unsaturated fatty acids, which it...; Region: FeeA_FeeB_like; cd01836 272560016079 active site 272560016080 catalytic triad [active] 272560016081 oxyanion hole [active] 272560016082 Pfam match to entry PF00657 Lipase_GDSL, Lipase/Acylhydrolase with GDSL-like motif , score 1.6, E-value 0.0074 272560016083 Signal peptide predicted for BPSL3358 by SignalP 2.0 HMM (Signal peptide probabilty 0.930) with cleavage site probability 0.299 between residues 38 and 39; signal peptide 272560016084 putative oxidoreductase; Provisional; Region: PRK11579 272560016085 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408 272560016086 LabA_like proteins; Region: LabA_like; cd06167 272560016087 Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894 272560016088 1 probable transmembrane helix predicted for BPSL3358 by TMHMM2.0 at aa 20-42 272560016089 Pfam match to entry PF01408 GFO_IDH_MocA, Oxidoreductase, NAD-binding Rossmann fold , score 117.0, E-value 2.3e-32 272560016090 Pfam match to entry PF02894 GFO_IDH_MocA_C, Oxidoreductase, C-terminal alpha/beta domain , score 75.7, E-value 6.4e-20 272560016091 glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389 272560016092 Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571 272560016093 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 272560016094 Pfam match to entry PF01571 GCV_T, Glycine cleavage T-protein (aminomethyl transferase) , score 407.0, E-value 1.2e-119 272560016095 Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848 272560016096 lipoyl attachment site [posttranslational modification]; other site 272560016097 Pfam match to entry PF01597 GCV_H, Glycine cleavage H-protein , score 188.5, E-value 7.2e-54 272560016098 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560016099 glycine dehydrogenase; Provisional; Region: PRK05367 272560016100 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 272560016101 tetramer interface [polypeptide binding]; other site 272560016102 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560016103 catalytic residue [active] 272560016104 Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613 272560016105 tetramer interface [polypeptide binding]; other site 272560016106 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560016107 catalytic residue [active] 272560016108 Pfam match to entry PF02347 GDC-P, Glycine cleavage system P-protein , score 828.4, E-value 1.7e-246 272560016109 Alginate lyase; Region: Alginate_lyase; pfam05426 272560016110 1 probable transmembrane helix predicted for BPSL3363 by TMHMM2.0 at aa 17-39 272560016111 L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720 272560016112 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 272560016113 Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313 272560016114 Pfam match to entry PF03315 SDH_beta, Serine dehydratase beta chain , score 199.4, E-value 3.6e-57 272560016115 Pfam match to entry PF03313 SDH_alpha, Serine dehydratase alpha chain , score 586.3, E-value 1.2e-173 272560016116 HemX; Region: HemX; cl19375 272560016117 1 probable transmembrane helix predicted for BPSL3365 by TMHMM2.0 at aa 326-346 272560016118 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016119 thiamine pyrophosphate protein; Validated; Region: PRK08199 272560016120 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560016121 PYR/PP interface [polypeptide binding]; other site 272560016122 dimer interface [polypeptide binding]; other site 272560016123 TPP binding site [chemical binding]; other site 272560016124 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560016125 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568 272560016126 TPP-binding site [chemical binding]; other site 272560016127 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 180.3, E-value 2.1e-51 272560016128 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 36.9, E-value 3e-08 272560016129 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 164.1, E-value 1.5e-46 272560016130 PS00187 Thiamine pyrophosphate enzymes signature. 272560016131 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560016132 Helix-turn-helix domain; Region: HTH_18; pfam12833 272560016133 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 20.6, E-value 0.0024 272560016134 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 25.9, E-value 6.2e-05 272560016135 Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like; Region: ALDH_ACDHII-AcoD; cd07116 272560016136 NAD(P) binding site [chemical binding]; other site 272560016137 catalytic residues [active] 272560016138 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 806.3, E-value 7.1e-240 272560016139 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560016140 PS00070 Aldehyde dehydrogenases cysteine active site. 272560016141 1 probable transmembrane helix predicted for BPSL3370 by TMHMM2.0 at aa 29-51 272560016142 ethanolamine ammonia-lyase small subunit; Provisional; Region: PRK05465 272560016143 ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067 272560016144 ethanolamine permease; Region: 2A0305; TIGR00908 272560016145 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560016146 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -109.8, E-value 9.1e-08 272560016147 12 probable transmembrane helices predicted for BPSL3373 by TMHMM2.0 at aa 45-67, 71-93, 120-142, 157-179, 186-208, 223-245, 257-279, 309-331, 359-376, 391-413, 426-448 and 452-471 272560016148 Acyltransferase family; Region: Acyl_transf_3; pfam01757 272560016149 10 probable transmembrane helices predicted for BPSL3374 by TMHMM2.0 at aa 13-35, 40-62, 83-105, 125-147, 180-202, 206-228, 241-263, 268-285, 306-328 and 338-360 272560016150 Signal peptide predicted for BPSL3375 by SignalP 2.0 HMM (Signal peptide probabilty 0.963) with cleavage site probability 0.849 between residues 27 and 28; signal peptide 272560016151 Conserved TM helix; Region: TM_helix; pfam05552 272560016152 Conserved TM helix; Region: TM_helix; pfam05552 272560016153 Conserved TM helix; Region: TM_helix; pfam05552 272560016154 11 probable transmembrane helices predicted for BPSL3376 by TMHMM2.0 at aa 32-54, 88-110, 125-147, 178-195, 210-232, 265-287, 302-324, 361-380, 395-417, 437-456 and 460-482 272560016155 Double zinc ribbon; Region: DZR; pfam12773 272560016156 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 272560016157 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560016158 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 272560016159 6 probable transmembrane helices predicted for BPSL3378 by TMHMM2.0 at aa 231-253, 273-295, 434-456, 471-493, 784-806 and 810-832 272560016160 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 109.3, E-value 4.7e-30 272560016161 PS00154 E1-E2 ATPases phosphorylation site. 272560016162 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 316.5, E-value 2e-92 272560016163 Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047 272560016164 Helix-Turn-Helix DNA binding domain of the CadR and PbrR transcription regulators; Region: HTH_CadR-PbrR; cd04784 272560016165 DNA binding residues [nucleotide binding] 272560016166 dimer interface [polypeptide binding]; other site 272560016167 putative metal binding site [ion binding]; other site 272560016168 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 67.3, E-value 2.1e-17 272560016169 PS00552 Bacterial regulatory proteins, merR family signature. 272560016170 Predicted transcriptional regulators [Transcription]; Region: COG1695 272560016171 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family , score 32.1, E-value 2e-07 272560016172 Probable gene remnant. Similar to the C-terminal regions of Rhizobium meliloti oxidoreductase rb0708 or smb21129 SWALL:Q92VJ3 (EMBL:AL603644) (442 aa) fasta scores: E(): 2e-29, 41.43% id in 251 aa, and Bradyrhizobium japonicum oxidoreductase blr7970 SWALL:Q89C28 (EMBL:AP005964) (470 aa) fasta scores: E(): 1.8e-21, 36.39% id in 261 aa. CDS contains frameshift mutations after codons 71 and 161; oxidoreductase (fragment) 272560016173 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 82.2, E-value 3.9e-23 272560016174 Signal peptide predicted for BPSL3383 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.817 between residues 34 and 35; signal peptide 272560016175 lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096 272560016176 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560016177 substrate binding pocket [chemical binding]; other site 272560016178 membrane-bound complex binding site; other site 272560016179 hinge residues; other site 272560016180 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 243.7, E-value 1.7e-70 272560016181 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560016182 methionine aminotransferase; Validated; Region: PRK09082 272560016183 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560016184 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560016185 homodimer interface [polypeptide binding]; other site 272560016186 catalytic residue [active] 272560016187 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 77.7, E-value 1.6e-20 272560016188 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560016189 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560016190 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 52.3, E-value 6.9e-13 272560016191 PS01081 Bacterial regulatory proteins, tetR family signature. 272560016192 isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561 272560016193 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560016194 active site 272560016195 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 18.9, E-value 4.5e-05 272560016196 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 67.0, E-value 2.7e-17 272560016197 PS00072 Acyl-CoA dehydrogenases signature 1. 272560016198 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 165.0, E-value 8.5e-47 272560016199 PS00073 Acyl-CoA dehydrogenases signature 2. 272560016200 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 272560016201 Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929 272560016202 acyl-activating enzyme (AAE) consensus motif; other site 272560016203 putative AMP binding site [chemical binding]; other site 272560016204 putative active site [active] 272560016205 putative CoA binding site [chemical binding]; other site 272560016206 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 407.2, E-value 1e-119 272560016207 PS00455 AMP-binding domain signature. 272560016208 Signal peptide predicted for BPSL3388 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.999 between residues 25 and 26; signal peptide 272560016209 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560016210 dimerization interface [polypeptide binding]; other site 272560016211 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560016212 ligand binding site [chemical binding]; other site 272560016213 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 10.5, E-value 6.7e-06 272560016214 trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809 272560016215 Predicted transcriptional regulator [Transcription]; Region: COG3905 272560016216 DNA-binding domain of Proline dehydrogenase; Region: Pro_dh-DNA_bdg; pfam14850 272560016217 Proline dehydrogenase; Region: Pro_dh; pfam01619 272560016218 Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125 272560016219 Glutamate binding site [chemical binding]; other site 272560016220 NAD binding site [chemical binding]; other site 272560016221 catalytic residues [active] 272560016222 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 305.2, E-value 5.3e-89 272560016223 PS00070 Aldehyde dehydrogenases cysteine active site. 272560016224 Pfam match to entry PF01619 Pro_dh, Proline dehydrogenase , score 592.2, E-value 2.1e-175 272560016225 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560016226 primosome assembly protein PriA; Validated; Region: PRK05580 272560016227 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560016228 ATP binding site [chemical binding]; other site 272560016229 putative Mg++ binding site [ion binding]; other site 272560016230 helicase superfamily c-terminal domain; Region: HELICc; smart00490 272560016231 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 32.2, E-value 7.7e-07 272560016232 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016233 Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717 272560016234 substrate binding site [chemical binding]; other site 272560016235 active site 272560016236 Pfam match to entry PF01208 URO-D, Uroporphyrinogen decarboxylase (URO-D) , score 552.1, E-value 2.4e-163 272560016237 PS00907 Uroporphyrinogen decarboxylase signature 2. 272560016238 PS00906 Uroporphyrinogen decarboxylase signature 1. 272560016239 Signal peptide predicted for BPSL3392 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.991 between residues 19 and 20; signal peptide 272560016240 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560016241 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560016242 substrate binding pocket [chemical binding]; other site 272560016243 membrane-bound complex binding site; other site 272560016244 hinge residues; other site 272560016245 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 133.5, E-value 2.5e-37 272560016246 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560016247 CoA binding domain; Region: CoA_binding; cl17356 272560016248 AMP-binding domain protein; Validated; Region: PRK08315 272560016249 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_2; cd05917 272560016250 acyl-activating enzyme (AAE) consensus motif; other site 272560016251 putative AMP binding site [chemical binding]; other site 272560016252 putative active site [active] 272560016253 putative CoA binding site [chemical binding]; other site 272560016254 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 439.3, E-value 2.3e-129 272560016255 PS00455 AMP-binding domain signature. 272560016256 F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571 272560016257 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 272560016258 gamma subunit interface [polypeptide binding]; other site 272560016259 epsilon subunit interface [polypeptide binding]; other site 272560016260 LBP interface [polypeptide binding]; other site 272560016261 Pfam match to entry PF00401 ATP-synt_DE, ATP synthase, Delta/Epsilon chain, long alpha-helix domain , score 21.3, E-value 0.0015 272560016262 Pfam match to entry PF02823 ATP-synt_DE_N, ATP synthase, Delta/Epsilon chain, beta-sandwich domain , score 119.7, E-value 3.5e-33 272560016263 F0F1 ATP synthase subunit beta; Validated; Region: PRK09280 272560016264 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560016265 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 272560016266 alpha subunit interaction interface [polypeptide binding]; other site 272560016267 Walker A motif; other site 272560016268 ATP binding site [chemical binding]; other site 272560016269 Walker B motif; other site 272560016270 inhibitor binding site; inhibition site 272560016271 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 272560016272 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain , score 181.3, E-value 1e-51 272560016273 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 471.8, E-value 3.6e-139 272560016274 PS00152 ATP synthase alpha and beta subunits signature. 272560016275 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016276 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 90.8, E-value 1.8e-24 272560016277 mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151 272560016278 core domain interface [polypeptide binding]; other site 272560016279 delta subunit interface [polypeptide binding]; other site 272560016280 epsilon subunit interface [polypeptide binding]; other site 272560016281 Pfam match to entry PF00231 ATP-synt, ATP synthase , score 470.0, E-value 1.3e-138 272560016282 PS00153 ATP synthase gamma subunit signature. 272560016283 F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281 272560016284 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560016285 F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132 272560016286 beta subunit interaction interface [polypeptide binding]; other site 272560016287 Walker A motif; other site 272560016288 ATP binding site [chemical binding]; other site 272560016289 Walker B motif; other site 272560016290 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 272560016291 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain , score 113.2, E-value 3.2e-31 272560016292 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 528.1, E-value 4e-156 272560016293 PS00152 ATP synthase alpha and beta subunits signature. 272560016294 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016295 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 75.4, E-value 7.5e-20 272560016296 F0F1 ATP synthase subunit delta; Validated; Region: PRK05758 272560016297 Pfam match to entry PF00213 OSCP, ATP synthase delta (OSCP) subunit , score 130.7, E-value 1.8e-36 272560016298 F0F1 ATP synthase subunit B; Validated; Region: PRK05759 272560016299 F0F1 ATP synthase subunit B; Provisional; Region: PRK14471; cl17192 272560016300 Pfam match to entry PF00430 ATP-synt_B, ATP synthase B/B' CF(0) , score 94.9, E-value 1.1e-25 272560016301 F0F1 ATP synthase subunit C; Validated; Region: PRK06876 272560016302 Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C , score 70.6, E-value 2.2e-18 272560016303 2 probable transmembrane helices predicted for BPSL3401 by TMHMM2.0 at aa 15-37 and 58-80 272560016304 PS00605 ATP synthase c subunit signature. 272560016305 F0F1 ATP synthase subunit A; Validated; Region: PRK05815 272560016306 Pfam match to entry PF00119 ATP-synt_A, ATP synthase A chain , score 133.7, E-value 2.2e-37 272560016307 5 probable transmembrane helices predicted for BPSL3402 by TMHMM2.0 at aa 47-66, 95-117, 152-171, 218-240 and 260-282 272560016308 PS00449 ATP synthase a subunit signature. 272560016309 ATP synthase I chain; Region: ATP_synt_I; pfam03899 272560016310 Signal peptide predicted for BPSL3403 by SignalP 2.0 HMM (Signal peptide probabilty 0.975) with cleavage site probability 0.783 between residues 20 and 21; signal peptide 272560016311 3 probable transmembrane helices predicted for BPSL3403 by TMHMM2.0 at aa 20-39, 51-73 and 77-99 272560016312 Anion permease ArsB/NhaD. These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life. A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221 272560016313 Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471 272560016314 transmembrane helices; other site 272560016315 10 probable transmembrane helices predicted for BPSL3404 by TMHMM2.0 at aa 28-50, 60-82, 95-117, 137-154, 174-196, 226-248, 260-282, 297-319, 326-348 and 358-380 272560016316 ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180 272560016317 ParB-like nuclease domain; Region: ParBc; pfam02195 272560016318 Pfam match to entry PF02195 ParBc, ParB-like nuclease domain , score 125.9, E-value 5e-35 272560016319 ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192 272560016320 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 272560016321 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560016322 P-loop; other site 272560016323 Magnesium ion binding site [ion binding]; other site 272560016324 Pfam match to entry PF00991 ParA, ParA family ATPase , score 126.1, E-value 4.3e-35 272560016325 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357 272560016326 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560016327 S-adenosylmethionine binding site [chemical binding]; other site 272560016328 Pfam match to entry PF02527 GidB, Glucose inhibited division protein , score 199.3, E-value 3.9e-57 272560016329 PS00044 Bacterial regulatory proteins, lysR family signature. 272560016330 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192 272560016331 NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206 272560016332 GidA associated domain 3; Region: GIDA_assoc_3; pfam13932 272560016333 Pfam match to entry PF01134 GIDA, Glucose inhibited division protein A , score 1408.2, E-value 0 272560016334 PS01281 Glucose inhibited division protein A family signature 2. 272560016335 PS01280 Glucose inhibited division protein A family signature 1. 272560016336 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560016337 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560016338 Walker A/P-loop; other site 272560016339 ATP binding site [chemical binding]; other site 272560016340 Q-loop/lid; other site 272560016341 ABC transporter signature motif; other site 272560016342 Walker B; other site 272560016343 D-loop; other site 272560016344 H-loop/switch region; other site 272560016345 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 148.5, E-value 7.5e-42 272560016346 PS00211 ABC transporters family signature. 272560016347 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016348 Signal peptide predicted for BPSL3410 by SignalP 2.0 HMM (Signal peptide probabilty 0.999) with cleavage site probability 0.843 between residues 27 and 28; signal peptide 272560016349 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560016350 TM-ABC transporter signature motif; other site 272560016351 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560016352 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560016353 Walker A/P-loop; other site 272560016354 ATP binding site [chemical binding]; other site 272560016355 Q-loop/lid; other site 272560016356 ABC transporter signature motif; other site 272560016357 Walker B; other site 272560016358 D-loop; other site 272560016359 H-loop/switch region; other site 272560016360 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 206.4, E-value 2.9e-59 272560016361 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016362 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 67.7, E-value 1.6e-17 272560016363 9 probable transmembrane helices predicted for BPSL3410 by TMHMM2.0 at aa 9-26, 36-58, 65-82, 86-108, 115-137, 161-183, 207-229, 249-271 and 284-306 272560016364 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560016365 TM-ABC transporter signature motif; other site 272560016366 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 4.4, E-value 7e-07 272560016367 9 probable transmembrane helices predicted for BPSL3411 by TMHMM2.0 at aa 17-39, 61-83, 96-113, 123-145, 157-179, 199-221, 255-277, 287-309 and 316-338 272560016368 Signal peptide predicted for BPSL3412 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.975 between residues 24 and 25; signal peptide 272560016369 Type I periplasmic binding component of ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in uptake of amino acids; Region: PBP1_ABC-type_HAAT_like; cd06333 272560016370 putative ligand binding site [chemical binding]; other site 272560016371 Signal peptide predicted for BPSL3414 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.403 between residues 23 and 24; signal peptide 272560016372 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560016373 TM-ABC transporter signature motif; other site 272560016374 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 35.9, E-value 2.6e-08 272560016375 8 probable transmembrane helices predicted for BPSL3414 by TMHMM2.0 at aa 7-29, 44-66, 79-101, 105-123, 152-174, 204-226, 239-261 and 291-313 272560016376 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560016377 TM-ABC transporter signature motif; other site 272560016378 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 142.6, E-value 4.6e-40 272560016379 8 probable transmembrane helices predicted for BPSL3415 by TMHMM2.0 at aa 15-37, 39-61, 65-87, 100-122, 148-167, 197-219, 229-251 and 264-286 272560016380 Signal peptide predicted for BPSL3416 by SignalP 2.0 HMM (Signal peptide probabilty 1.000) with cleavage site probability 0.994 between residues 24 and 25; signal peptide 272560016381 Periplasmic solute-binding domain of active transport proteins that belong to the type I periplasmic binding fold protein family; Region: PBP1_SBP_like_1; cd06327 272560016382 putative ligand binding site [chemical binding]; other site 272560016383 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560016384 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560016385 Walker A/P-loop; other site 272560016386 ATP binding site [chemical binding]; other site 272560016387 Q-loop/lid; other site 272560016388 ABC transporter signature motif; other site 272560016389 Walker B; other site 272560016390 D-loop; other site 272560016391 H-loop/switch region; other site 272560016392 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 145.4, E-value 6.6e-41 272560016393 PS00211 ABC transporters family signature. 272560016394 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560016395 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560016396 Walker A/P-loop; other site 272560016397 ATP binding site [chemical binding]; other site 272560016398 Q-loop/lid; other site 272560016399 ABC transporter signature motif; other site 272560016400 Walker B; other site 272560016401 D-loop; other site 272560016402 H-loop/switch region; other site 272560016403 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 160.3, E-value 2.2e-45 272560016404 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016405 choline dehydrogenase; Validated; Region: PRK02106 272560016406 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560016407 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560016408 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score 622.2, E-value 1.9e-184 272560016409 PS00624 GMC oxidoreductases signature 2. 272560016410 PS00623 GMC oxidoreductases signature 1. 272560016411 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 272560016412 tetrameric interface [polypeptide binding]; other site 272560016413 NAD binding site [chemical binding]; other site 272560016414 catalytic residues [active] 272560016415 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 584.2, E-value 5.1e-173 272560016416 PS00070 Aldehyde dehydrogenases cysteine active site. 272560016417 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560016418 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560016419 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560016420 dimerization interface [polypeptide binding]; other site 272560016421 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 102.2, E-value 6.5e-28 272560016422 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 103.1, E-value 3.4e-28 272560016423 Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890 272560016424 putative active site [active] 272560016425 putative metal binding residues [ion binding]; other site 272560016426 signature motif; other site 272560016427 putative triphosphate binding site [ion binding]; other site 272560016428 dimer interface [polypeptide binding]; other site 272560016429 Pfam match to entry PF01928 Adenylate_cyc_2, Adenylate cyclase , score 1.0, E-value 1.5e-07 272560016430 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560016431 helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344 272560016432 putative DNA binding site [nucleotide binding]; other site 272560016433 putative Zn2+ binding site [ion binding]; other site 272560016434 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 125.9, E-value 5e-35 272560016435 Prokaryotic phenylalanine-4-hydroxylase (pro_PheOH); a member of the biopterin-dependent aromatic amino acid hydroxylase family of non-heme, iron(II)-dependent enzymes that also includes the eukaryotic proteins, phenylalanine-4-hydroxylase (eu_PheOH); Region: pro_PheOH; cd03348 272560016436 cofactor binding site; other site 272560016437 metal binding site [ion binding]; metal-binding site 272560016438 Pfam match to entry PF00351 biopterin_H, Biopterin-dependent aromatic amino acid hydroxylase , score -86.8, E-value 2.7e-10 272560016439 PS00367 Biopterin-dependent aromatic amino acid hydroxylases signature. 272560016440 Pfam match to entry PF01329 Pterin_4a, Pterin 4 alpha carbinolamine dehydratase , score 131.9, E-value 7.6e-37 272560016441 PCD_DCoH: The bifunctional protein pterin-4alpha-carbinolamine dehydratase (PCD), also known as DCoH (dimerization cofactor of hepatocyte nuclear factor-1), is both a transcription activator and a metabolic enzyme. DCoH stimulates gene expression by...; Region: PCD_DCoH_subfamily_b; cd00914 272560016442 aromatic arch; other site 272560016443 DCoH dimer interaction site [polypeptide binding]; other site 272560016444 DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site 272560016445 DCoH tetramer interaction site [polypeptide binding]; other site 272560016446 substrate binding site [chemical binding]; other site 272560016447 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560016448 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560016449 active site 272560016450 phosphorylation site [posttranslational modification] 272560016451 intermolecular recognition site; other site 272560016452 dimerization interface [polypeptide binding]; other site 272560016453 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560016454 DNA binding site [nucleotide binding] 272560016455 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 135.4, E-value 6.6e-38 272560016456 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 71.5, E-value 1.2e-18 272560016457 Signal peptide predicted for BPSL3427 by SignalP 2.0 HMM (Signal peptide probabilty 0.871) with cleavage site probability 0.792 between residues 33 and 34; signal peptide 272560016458 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 272560016459 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560016460 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560016461 dimer interface [polypeptide binding]; other site 272560016462 phosphorylation site [posttranslational modification] 272560016463 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560016464 ATP binding site [chemical binding]; other site 272560016465 Mg2+ binding site [ion binding]; other site 272560016466 G-X-G motif; other site 272560016467 2 probable transmembrane helices predicted for BPSL3427 by TMHMM2.0 at aa 15-37 and 160-182 272560016468 Pfam match to entry PF00672 HAMP, HAMP domain , score 31.1, E-value 1.7e-06 272560016469 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 62.6, E-value 5.4e-16 272560016470 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 124.1, E-value 1.7e-34 272560016471 Proteins containing SET domain [General function prediction only]; Region: COG2940 272560016472 SET domain; Region: SET; pfam00856 272560016473 Pfam match to entry PF00856 SET, SET domain , score 105.6, E-value 6.2e-29 272560016474 Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932 272560016475 active site 272560016476 FMN binding site [chemical binding]; other site 272560016477 substrate binding site [chemical binding]; other site 272560016478 homotetramer interface [polypeptide binding]; other site 272560016479 catalytic residue [active] 272560016480 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 225.5, E-value 5e-65 272560016481 GMP synthase - Glutamine amidotransferase domain [Nucleotide transport and metabolism]; Region: GuaA; COG0518 272560016482 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_1; cd01741 272560016483 catalytic triad [active] 272560016484 Pfam match to entry PF00117 GATase, Glutamine amidotransferase class-I , score 37.0, E-value 2.9e-11 272560016485 PS00442 Glutamine amidotransferases class-I active site. 272560016486 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560016487 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560016488 putative DNA binding site [nucleotide binding]; other site 272560016489 putative Zn2+ binding site [ion binding]; other site 272560016490 Pfam match to entry PF01047 MarR, MarR family , score 39.7, E-value 4.3e-09 272560016491 Plasmid replication region DNA-binding N-term; Region: KfrA_N; pfam11740 272560016492 Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974 272560016493 DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182 272560016494 active site 272560016495 Int/Topo IB signature motif; other site 272560016496 catalytic residues [active] 272560016497 DNA binding site [nucleotide binding] 272560016498 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score -12.1, E-value 0.0013 272560016499 Protein of unknown function (DUF2471); Region: DUF2471; pfam10616 272560016500 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560016501 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560016502 non-specific DNA binding site [nucleotide binding]; other site 272560016503 salt bridge; other site 272560016504 sequence-specific DNA binding site [nucleotide binding]; other site 272560016505 Cupin domain; Region: Cupin_2; pfam07883 272560016506 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016507 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 66.0, E-value 5.3e-17 272560016508 Predicted helix-turn-helix motif with score 1501.000, SD 4.30 at aa 38-59, sequence LTLDDLSRAAGVSKSMLSEIER 272560016509 8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858 272560016510 KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454 272560016511 substrate-cofactor binding pocket; other site 272560016512 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560016513 catalytic residue [active] 272560016514 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 202.1, E-value 5.7e-58 272560016515 PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 272560016516 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016517 L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396 272560016518 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560016519 NAD(P) binding site [chemical binding]; other site 272560016520 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 336.5, E-value 2e-98 272560016521 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560016522 Uncharacterized conserved protein [Function unknown]; Region: COG2353 272560016523 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560016524 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560016525 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 58.8, E-value 7.6e-15 272560016526 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016527 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3558 272560016528 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_7; cd06910 272560016529 putative active site [active] 272560016530 Zn binding site [ion binding]; other site 272560016531 Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445 272560016532 Pfam match to entry PF00180 isodh, Isocitrate/isopropylmalate dehydrogenase , score 337.8, E-value 7.8e-99 272560016533 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 272560016534 transcriptional activator TtdR; Provisional; Region: PRK09801 272560016535 Signal peptide predicted for BPSS0012 by SignalP 2.0 HMM (Signal peptide probability 0.835) with cleavage site probability 0.740 between residues 26 and 27; signal peptide 272560016536 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560016537 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479 272560016538 putative effector binding pocket; other site 272560016539 putative dimerization interface [polypeptide binding]; other site 272560016540 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 78.7, E-value 7.7e-21 272560016541 Predicted helix-turn-helix motif with score 1138.000, SD 3.06 at aa 20-41, sequence ASFSAAAEQLAVSPAYVSKRVA 272560016542 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 156.7, E-value 2.5e-44 272560016543 Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020 272560016544 6 probable transmembrane helices predicted for BPSS0013 by TMHMM2.0 at aa 13-30, 35-54, 75-97, 112-134, 155-174 and 179-196 272560016545 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560016546 GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047 272560016547 putative C-terminal domain interface [polypeptide binding]; other site 272560016548 putative GSH binding site (G-site) [chemical binding]; other site 272560016549 putative dimer interface [polypeptide binding]; other site 272560016550 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 272560016551 N-terminal domain interface [polypeptide binding]; other site 272560016552 dimer interface [polypeptide binding]; other site 272560016553 substrate binding pocket (H-site) [chemical binding]; other site 272560016554 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 66.8, E-value 3e-17 272560016555 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 26.9, E-value 3e-05 272560016556 2 probable transmembrane helices predicted for BPSS0015 by TMHMM2.0 at aa 2-21 and 31-53 272560016557 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 272560016558 Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209 272560016559 active site 272560016560 nucleophile elbow; other site 272560016561 Patatin phospholipase; Region: DUF3734; pfam12536 272560016562 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 86.3, E-value 4.2e-23 272560016563 3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK13394 272560016564 classical (c) SDRs; Region: SDR_c; cd05233 272560016565 NAD(P) binding site [chemical binding]; other site 272560016566 active site 272560016567 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 237.9, E-value 9.2e-69 272560016568 PS00061 Short-chain dehydrogenases/reductases family signature. 272560016569 acetoacetate decarboxylase; Provisional; Region: PRK02265 272560016570 Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671 272560016571 PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385 272560016572 active site 272560016573 6 probable transmembrane helices predicted for BPSS0019 by TMHMM2.0 at aa 19-41, 45-62, 69-91, 111-130, 137-154 and 159-181 272560016574 Pfam match to entry PF01569 PAP2, PAP2 superfamily , score 93.1, E-value 3.6e-25 272560016575 1 probable transmembrane helix predicted for BPSS0020 by TMHMM2.0 at aa 34-56 272560016576 Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375 272560016577 Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193 272560016578 FAD binding pocket [chemical binding]; other site 272560016579 FAD binding motif [chemical binding]; other site 272560016580 phosphate binding motif [ion binding]; other site 272560016581 NAD binding pocket [chemical binding]; other site 272560016582 Transcriptional regulator PadR-like family; Region: PadR; pfam03551 272560016583 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family , score 89.5, E-value 4.3e-24 272560016584 Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124 272560016585 Pfam match to entry PF00067 p450, Cytochrome P450 , score 36.8, E-value 8.6e-11 272560016586 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 272560016587 This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa; Region: ACD_sHsps_p23-like; cd00298 272560016588 Protein of unknown function (DUF692); Region: DUF692; cl01263 272560016589 B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293 272560016590 B12 binding site [chemical binding]; other site 272560016591 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560016592 Radical SAM superfamily; Region: Radical_SAM; pfam04055 272560016593 FeS/SAM binding site; other site 272560016594 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560016595 S-adenosylmethionine binding site [chemical binding]; other site 272560016596 Lysine efflux permease [General function prediction only]; Region: COG1279 272560016597 6 probable transmembrane helices predicted for BPSS0029 by TMHMM2.0 at aa 5-27, 40-62, 67-89, 122-144, 154-176 and 183-205 272560016598 Pfam match to entry PF01810 LysE, LysE type translocator , score 84.9, E-value 1.1e-22 272560016599 chromosome replication initiation inhibitor protein; Validated; Region: PRK03635 272560016600 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560016601 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560016602 dimerization interface [polypeptide binding]; other site 272560016603 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 66.2, E-value 4.5e-17 272560016604 Predicted helix-turn-helix motif with score 2067.000, SD 6.23 at aa 17-38, sequence GSFERAAKALNVSPSAVSQRVK 272560016605 PS00044 Bacterial regulatory proteins, lysR family signature. 272560016606 PS00070 Aldehyde dehydrogenases cysteine active site. 272560016607 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 53.1, E-value 4e-13 272560016608 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 272560016609 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560016610 ligand binding site [chemical binding]; other site 272560016611 flexible hinge region; other site 272560016612 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 272560016613 putative switch regulator; other site 272560016614 non-specific DNA interactions [nucleotide binding]; other site 272560016615 DNA binding site [nucleotide binding] 272560016616 sequence specific DNA binding site [nucleotide binding]; other site 272560016617 putative cAMP binding site [chemical binding]; other site 272560016618 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family , score 56.8, E-value 3e-14 272560016619 PS00042 Bacterial regulatory proteins, crp family signature. 272560016620 Predicted helix-turn-helix motif with score 1625.000, SD 4.72 at aa 204-225, sequence MTREDIGSYLGMTLETVSRTLS 272560016621 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 72.4, E-value 6.2e-19 272560016622 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560016623 Ligand Binding Site [chemical binding]; other site 272560016624 Pfam match to entry PF00582 Usp, Universal stress protein family , score 78.3, E-value 1.1e-20 272560016625 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 272560016626 dimer interface [polypeptide binding]; other site 272560016627 NADP binding site [chemical binding]; other site 272560016628 catalytic residues [active] 272560016629 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score -92.4, E-value 1.1e-11 272560016630 Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386 272560016631 Strictosidine synthase; Region: Str_synth; cl19733 272560016632 Pfam match to entry PF03758 SMP-30, Senescence marker protein-30 (SMP-30) , score -6.2, E-value 2.2e-11 272560016633 Protein of unknown function (DUF3005); Region: DUF3005; pfam11448 272560016634 Transcriptional activator HlyU; Region: HlyU; cl02273 272560016635 Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762 272560016636 serine O-acetyltransferase; Region: cysE; TIGR01172 272560016637 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 272560016638 trimer interface [polypeptide binding]; other site 272560016639 active site 272560016640 substrate binding site [chemical binding]; other site 272560016641 CoA binding site [chemical binding]; other site 272560016642 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 2.1, E-value 9.2 272560016643 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.0, E-value 0.24 272560016644 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 9.0, E-value 3.4 272560016645 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 10.2, E-value 2.4 272560016646 short chain dehydrogenase; Provisional; Region: PRK09134 272560016647 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560016648 NAD(P) binding site [chemical binding]; other site 272560016649 active site 272560016650 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 77.6, E-value 1.7e-20 272560016651 GTP cyclohydrolase I; Provisional; Region: folE; PRK09347 272560016652 active site 272560016653 Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I , score 166.5, E-value 2.9e-47 272560016654 PS00859 GTP cyclohydrolase I signature 1. 272560016655 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560016656 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560016657 The C-terminal substrate binding domain of LysR-type transcriptional regulators that are involved in the catabolism of dinitrotoluene, naphthalene and gamma-hexachlorohexane; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_NahR_LinR_like; cd08459 272560016658 substrate binding pocket [chemical binding]; other site 272560016659 dimerization interface [polypeptide binding]; other site 272560016660 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 86.4, E-value 3.9e-23 272560016661 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 75.1, E-value 9.5e-20 272560016662 Predicted helix-turn-helix motif with score 1352.000, SD 3.79 at aa 20-41, sequence RNVSRAGELLGVSQPRVSAALG 272560016663 4-hydroxybenzoate 3-monooxygenase; Validated; Region: PRK08243 272560016664 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiH; COG0654 272560016665 Pfam match to entry PF01494 FAD_binding_3, FAD binding domain , score 117.0, E-value 2.3e-32 272560016666 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 158.2, E-value 9e-45 272560016667 3-oxoacid CoA-transferase, A subunit; Region: pcaI_scoA_fam; TIGR02429 272560016668 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase , score 366.6, E-value 1.7e-107 272560016669 PS01273 CoA transferases signature 1. 272560016670 3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428 272560016671 Pfam match to entry PF01144 CoA_trans, Coenzyme A transferase , score 222.5, E-value 4e-64 272560016672 PS01274 CoA transferases signature 2. 272560016673 3-carboxy-cis,cis-muconate cycloisomerase; Provisional; Region: PRK09053 272560016674 prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597 272560016675 tetramer interface [polypeptide binding]; other site 272560016676 active site 272560016677 Pfam match to entry PF00206 lyase_1, Lyase , score 182.0, E-value 6.1e-52 272560016678 PS00163 Fumarate lyases signature. 272560016679 3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427 272560016680 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560016681 TAP-like protein; Region: Abhydrolase_4; pfam08386 272560016682 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 104.6, E-value 1.3e-28 272560016683 4-carboxymuconolactone decarboxylase; Region: decarb_PcaC; TIGR02425 272560016684 Pfam match to entry PF02627 CMD, Carboxymuconolactone decarboxylase , score 130.4, E-value 2.2e-36 272560016685 benzoate transport; Region: 2A0115; TIGR00895 272560016686 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560016687 putative substrate translocation pore; other site 272560016688 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 51.8, E-value 1e-12 272560016689 12 probable transmembrane helices predicted for BPSS0048 by TMHMM2.0 at aa 25-47, 62-84, 91-113, 117-139, 151-173, 177-199, 263-285, 295-317, 324-346, 350-372, 385-407 and 411-433 272560016690 PS00216 Sugar transport proteins signature 1. 272560016691 PS00217 Sugar transport proteins signature 2. 272560016692 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560016693 5 probable transmembrane helices predicted for BPSS0050 by TMHMM2.0 at aa 59-78, 98-120, 127-149, 201-223 and 236-255 272560016694 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560016695 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560016696 9 probable transmembrane helices predicted for BPSS0051 by TMHMM2.0 at aa 33-55, 60-82, 97-119, 157-179, 189-208, 235-257, 267-286, 307-329 and 369-391 272560016697 Chromate resistance exported protein; Region: Chrome_Resist; pfam09828 272560016698 Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059 272560016699 chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937 272560016700 Chromate transporter; Region: Chromate_transp; pfam02417 272560016701 11 probable transmembrane helices predicted for BPSS0053 by TMHMM2.0 at aa 20-39, 59-81, 88-110, 115-137, 150-181, 191-213, 225-247, 267-289, 294-316, 331-348 and 378-395 272560016702 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 55.6, E-value 7e-14 272560016703 Pfam match to entry PF02417 Chromate_transp, Chromate transporter , score 271.3, E-value 8.2e-79 272560016704 Signal peptide predicted for BPSS0054 by SignalP 2.0 HMM (Signal peptide probability 0.935) with cleavage site probability 0.761 between residues 24 and 25; signal peptide 272560016705 Chromate resistance exported protein; Region: Chrome_Resist; pfam09828 272560016706 Signal peptide predicted for BPSS0055 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23; signal peptide 272560016707 Domain of unknown function (DUF4142); Region: DUF4142; pfam13628 272560016708 Amicyanin is a type I blue copper protein that plays an essential role in electron transfer; Region: Amicyanin; cd13921 272560016709 Type 1 (T1) Cu binding site [ion binding]; other site 272560016710 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560016711 RNA polymerase sigma factor; Provisional; Region: PRK11922 272560016712 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560016713 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560016714 DNA binding residues [nucleotide binding] 272560016715 Predicted helix-turn-helix motif with score 1151.000, SD 3.11 at aa 171-192, sequence LSVEETAQCLGIPEATVRSRHF 272560016716 Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178 272560016717 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560016718 Walker A/P-loop; other site 272560016719 ATP binding site [chemical binding]; other site 272560016720 Q-loop/lid; other site 272560016721 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560016722 ABC transporter signature motif; other site 272560016723 Walker B; other site 272560016724 D-loop; other site 272560016725 H-loop/switch region; other site 272560016726 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560016727 Walker A/P-loop; other site 272560016728 ATP binding site [chemical binding]; other site 272560016729 Q-loop/lid; other site 272560016730 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048 272560016731 ABC transporter signature motif; other site 272560016732 Walker B; other site 272560016733 D-loop; other site 272560016734 H-loop/switch region; other site 272560016735 excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349 272560016736 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560016737 Walker A/P-loop; other site 272560016738 ATP binding site [chemical binding]; other site 272560016739 Q-loop/lid; other site 272560016740 ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270 272560016741 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560016742 Walker A/P-loop; other site 272560016743 ATP binding site [chemical binding]; other site 272560016744 Q-loop/lid; other site 272560016745 Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048 272560016746 ABC transporter signature motif; other site 272560016747 Walker B; other site 272560016748 D-loop; other site 272560016749 H-loop/switch region; other site 272560016750 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 36.2, E-value 6.4e-09 272560016751 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016752 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 62.7, E-value 5.2e-16 272560016753 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016754 PS00211 ABC transporters family signature. 272560016755 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 29.7, E-value 2e-08 272560016756 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016757 PS00211 ABC transporters family signature. 272560016758 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 63.5, E-value 2.9e-16 272560016759 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016760 PS00190 Cytochrome c family heme-binding site signature. 272560016761 PS00211 ABC transporters family signature. 272560016762 Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383 272560016763 H-NS histone family; Region: Histone_HNS; pfam00816 272560016764 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560016765 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 272560016766 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560016767 putative substrate translocation pore; other site 272560016768 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 215.4, E-value 5.6e-62 272560016769 12 probable transmembrane helices predicted for BPSS0061 by TMHMM2.0 at aa 66-83, 93-115, 122-141, 146-168, 189-211, 224-246, 275-297, 312-334, 341-363, 368-390, 403-425 and 435-454 272560016770 PS00216 Sugar transport proteins signature 1. 272560016771 PS00217 Sugar transport proteins signature 2. 272560016772 PS00216 Sugar transport proteins signature 1. 272560016773 Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms]; Region: COG4191 272560016774 PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524 272560016775 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560016776 dimer interface [polypeptide binding]; other site 272560016777 phosphorylation site [posttranslational modification] 272560016778 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560016779 ATP binding site [chemical binding]; other site 272560016780 Mg2+ binding site [ion binding]; other site 272560016781 G-X-G motif; other site 272560016782 2 probable transmembrane helices predicted for BPSS0062 by TMHMM2.0 at aa 12-34 and 316-338 272560016783 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 33.1, E-value 4.2e-07 272560016784 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 121.1, E-value 1.4e-33 272560016785 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560016786 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560016787 active site 272560016788 phosphorylation site [posttranslational modification] 272560016789 intermolecular recognition site; other site 272560016790 dimerization interface [polypeptide binding]; other site 272560016791 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560016792 Walker A motif; other site 272560016793 ATP binding site [chemical binding]; other site 272560016794 Walker B motif; other site 272560016795 arginine finger; other site 272560016796 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560016797 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 122.4, E-value 5.4e-34 272560016798 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 272560016799 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 413.7, E-value 1.1e-121 272560016800 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560016801 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560016802 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560016803 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 48.8, E-value 7.6e-12 272560016804 Predicted helix-turn-helix motif with score 1000.000, SD 2.59 at aa 415-436, sequence GQVAKAAELLGLPRKTLYDKIT 272560016805 2 probable transmembrane helices predicted for BPSS0064 by TMHMM2.0 at aa 83-105 and 109-131 272560016806 Signal peptide predicted for BPSS0065 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.834 between residues 31 and 32; signal peptide 272560016807 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 272560016808 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016809 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560016810 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560016811 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 4.5, E-value 0.87 272560016812 Predicted helix-turn-helix motif with score 1342.000, SD 3.76 at aa 100-121, sequence PSLARLASKLFLSERTLKRRLQ 272560016813 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.7, E-value 1.4e-07 272560016814 Signal peptide predicted for BPSS0067 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.782 between residues 33 and 34; signal peptide 272560016815 phospholipase C, phosphocholine-specific, Pseudomonas-type; Region: PC_PLC; TIGR03396 272560016816 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560016817 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560016818 Domain of unknown function (DUF756); Region: DUF756; pfam05506 272560016819 Pseudogene. Similar to Bacteriophage phiE125 TnpB SWALL:Q8W6R2 (EMBL:AF447491) (284 aa) fasta scores: E(): 4.2e-95, 85.21% id in 284 aa, and to Xanthomonas axonopodis transposase xac2432 SWALL:Q8PJU8 (EMBL:AE011880) (301 aa) fasta scores: E(): 4.2e-77, 68.12% id in 298 aa. CDS contains nonsense and frameshift mutations is distrupted by the integration of an IS element;transposase (pseudogene) 272560016820 Pfam match to entry PF00665 rve, Integrase core domain , score 36.6, E-value 1.5e-10 272560016821 Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826 272560016822 Helix-turn-helix domain; Region: HTH_38; pfam13936 272560016823 Integrase core domain; Region: rve; pfam00665 272560016824 Predicted helix-turn-helix motif with score 1119.000, SD 3.00 at aa 1-170, sequence METEAAALACNVSQPLGPRWLREAGGVAPIDLAPHSGRYLPFSEREEIALLWAQDCS VREISRRLQRSPSTISRELRRNAATRGGTLVYRATVAQWKAEGAAERPNASKLAEND QLRTYVQDRLAGTVTDYRGEPIPGPNVPWKGRRQGRHADRRWATCWSPEQISRRIQ 272560016825 Predicted helix-turn-helix motif with score 1216.000, SD 3.33 at aa 1-22, sequence METEAAALACNVSQPLGPRWLR 272560016826 Predicted helix-turn-helix motif with score 1216.000, SD 3.33 at aa 56-22, sequence REAGGVAPIDLAPHSGRYLPFSEREEIALLWAQDC 272560016827 Predicted helix-turn-helix motif with score 1216.000, SD 3.33 at aa 56-77, sequence CSVREISRRLQRSPSTISRELR 272560016828 Predicted helix-turn-helix motif with score 1119.000, SD 3.00 at aa 149-170, sequence GRHADRRWATCWSPEQISRRIQ 272560016829 Pfam match to entry PF00665 rve, Integrase core domain , score 72.5, E-value 5.7e-19 272560016830 PS01043 Transposases, IS30 family, signature. 272560016831 Pfam match to entry PF00665 rve, Integrase core domain , score 18.5, E-value 2.5e-05 272560016832 Pseudogene. Similar to Burkholderia cepacia insertion element IS401 hypothetical 12.4 kDa protein SWALL:YISX_BURCE (SWALL:Q51647) (107 aa) fasta scores: E(): 2.6e-25, 72.22% id in 108 aa, and to Bacteriophage phiE125 TnpA SWALL:Q8W6R1 (EMBL:AF447491) (92 aa) fasta scores: E(): 8.6e-25, 84.78% id in 92 aa. CDS contains frameshift mutation after codon 77;IS element hypothetical protein (pseudogene) 272560016833 Partial CDS. Similar to the C-terminal region of Ralstonia solanacearum hypothetical protein rsc3358 or rs02633 SWALL:Q8XU36 (EMBL:AL646074) (179 aa) fasta scores: E(): 0.00013, 46.51% id in 43 aa, and of Neurospora crassa histone H3 methyltransferase Dim-5 SWALL:Q8X225 (EMBL:AF419248) (318 aa) fasta scores: E(): 0.49, 37.5% id in 48 aa;conserved hypothetical protein (fragment) 272560016834 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 272560016835 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560016836 Spectrin repeat; Region: Spectrin; cl02488 272560016837 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560016838 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560016839 dimer interface [polypeptide binding]; other site 272560016840 conserved gate region; other site 272560016841 putative PBP binding loops; other site 272560016842 ABC-ATPase subunit interface; other site 272560016843 6 probable transmembrane helices predicted for BPSS0075 by TMHMM2.0 at aa 21-43, 88-110, 119-141, 170-192, 213-235 and 270-292 272560016844 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 40.4, E-value 2.7e-09 272560016845 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560016846 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560016847 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560016848 dimer interface [polypeptide binding]; other site 272560016849 conserved gate region; other site 272560016850 putative PBP binding loops; other site 272560016851 ABC-ATPase subunit interface; other site 272560016852 6 probable transmembrane helices predicted for BPSS0076 by TMHMM2.0 at aa 12-34, 70-92, 105-127, 133-155, 208-227 and 237-259 272560016853 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 53.3, E-value 3.6e-13 272560016854 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 272560016855 Signal peptide predicted for BPSS0077 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 18 and 19; signal peptide 272560016856 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 36.7, E-value 3.6e-08 272560016857 H-NS histone family; Region: Histone_HNS; pfam00816 272560016858 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560016859 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 272560016860 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560016861 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560016862 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 272560016863 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253 272560016864 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016865 Protein of unknown function (DUF3274); Region: DUF3274; pfam11678 272560016866 PS00120 Lipases, serine active site. 272560016867 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016868 Protein of unknown function (DUF2875); Region: DUF2875; pfam11394 272560016869 Uncharacterized conserved protein [Function unknown]; Region: COG4104 272560016870 Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894 272560016871 Pfam match to entry PF01894 UPF0047, Uncharacterised protein family UPF0047 , score 198.4, E-value 7.2e-57 272560016872 TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947 272560016873 catalytic residues [active] 272560016874 Signal peptide predicted for BPSS0083 by SignalP 2.0 HMM (Signal peptide probability 0.684) with cleavage site probability 0.590 between residues 49 and 50; signal peptide 272560016875 Gene remnant. Similar to internal region of Burkholderia cepacia OpcP1 SWALL:Q45106 (EMBL:D63823) (361 aa) fasta scores: E(): 1.9e-05, 58.06% id in 31 aa, and Ralstonia solanacearum probable porin signal peptide protein rsc2108 or rs01496 SWALL:Q8XXK5 (EMBL:AL646068) (381 aa) fasta scores: E(): 0.00028, 61.29% id in 31 aa. Feature lacks translational stop and start codons; porin-related protein (fragment) 272560016876 Integral membrane protein (DUF2244); Region: DUF2244; pfam10003 272560016877 2 probable transmembrane helices predicted for BPSS0085 by TMHMM2.0 at aa 85-104 and 108-130 272560016878 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 272560016879 Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of...; Region: Cyt_c_Oxidase_I; cd01663 272560016880 Subunit I/III interface [polypeptide binding]; other site 272560016881 D-pathway; other site 272560016882 Subunit I/VIIc interface [polypeptide binding]; other site 272560016883 Subunit I/IV interface [polypeptide binding]; other site 272560016884 Subunit I/II interface [polypeptide binding]; other site 272560016885 Low-spin heme (heme a) binding site [chemical binding]; other site 272560016886 Subunit I/VIIa interface [polypeptide binding]; other site 272560016887 Subunit I/VIa interface [polypeptide binding]; other site 272560016888 Dimer interface; other site 272560016889 Putative water exit pathway; other site 272560016890 Binuclear center (heme a3/CuB) [ion binding]; other site 272560016891 K-pathway; other site 272560016892 Subunit I/Vb interface [polypeptide binding]; other site 272560016893 Putative proton exit pathway; other site 272560016894 Subunit I/VIb interface; other site 272560016895 Subunit I/VIc interface [polypeptide binding]; other site 272560016896 Electron transfer pathway; other site 272560016897 Subunit I/VIIIb interface [polypeptide binding]; other site 272560016898 Subunit I/VIIb interface [polypeptide binding]; other site 272560016899 12 probable transmembrane helices predicted for BPSS0086 by TMHMM2.0 at aa 54-76, 102-121, 141-163, 183-205, 225-247, 272-294, 301-323, 338-360, 373-395, 410-432, 445-467 and 487-509 272560016900 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score 830.6, E-value 3.5e-247 272560016901 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560016902 1 probable transmembrane helix predicted for BPSS0087 by TMHMM2.0 at aa 48-70 272560016903 Signal peptide predicted for BPSS0088 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.962 between residues 21 and 22; signal peptide 272560016904 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560016905 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560016906 trimer interface [polypeptide binding]; other site 272560016907 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560016908 trimer interface [polypeptide binding]; other site 272560016909 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560016910 trimer interface [polypeptide binding]; other site 272560016911 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560016912 trimer interface [polypeptide binding]; other site 272560016913 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560016914 trimer interface [polypeptide binding]; other site 272560016915 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560016916 trimer interface [polypeptide binding]; other site 272560016917 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560016918 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 0.1, E-value 1.7e+02 272560016919 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 0.1, E-value 1.7e+02 272560016920 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 2.6, E-value 56 272560016921 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 0.1, E-value 1.7e+02 272560016922 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 1.9, E-value 76 272560016923 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 1.9, E-value 76 272560016924 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 1.3, E-value 1e+02 272560016925 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 2.6, E-value 56 272560016926 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 2.6, E-value 56 272560016927 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 0.1, E-value 1.7e+02 272560016928 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 1.9, E-value 76 272560016929 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 2.6, E-value 56 272560016930 Pfam match to entry PF02339 SGXXSG, Aggrecan core protein repeat , score 2.6, E-value 56 272560016931 PhoPQ-activated pathogenicity-related protein; Region: PhoPQ_related; cl01750 272560016932 Signal peptide predicted for BPSS0089 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.917 between residues 23 and 24; signal peptide 272560016933 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560016934 Signal peptide predicted for BPSS0090 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.995 between residues 40 and 41; signal peptide 272560016935 YfaZ precursor; Region: YfaZ; pfam07437 272560016936 PS00107 Protein kinases ATP-binding region signature. 272560016937 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 272560016938 1 probable transmembrane helix predicted for BPSS0091 by TMHMM2.0 at aa 5-24 272560016939 Pfam match to entry PF00419 Fimbrial, Fimbrial protein , score 98.8, E-value 6.7e-27 272560016940 Signal peptide predicted for BPSS0092 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.975 between residues 18 and 19; signal peptide 272560016941 putative chaperone protein EcpD; Provisional; Region: PRK09926 272560016942 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560016943 Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753 272560016944 Pfam match to entry PF00345 pili_assembly, Gram-negative pili assembly chaperone, N-terminal domain , score 228.2, E-value 7.9e-66 272560016945 PS00635 Gram-negative pili assembly chaperone signature. 272560016946 Pfam match to entry PF02753 pili_assembly_C, Gram-negative pili assembly chaperone, C-terminal domain , score 37.7, E-value 1.8e-08 272560016947 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560016948 PapC N-terminal domain; Region: PapC_N; pfam13954 272560016949 Outer membrane usher protein; Region: Usher; pfam00577 272560016950 PapC C-terminal domain; Region: PapC_C; pfam13953 272560016951 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score 976.4, E-value 4.7e-291 272560016952 PS00107 Protein kinases ATP-binding region signature. 272560016953 Signal peptide predicted for BPSS0094 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.724 between residues 33 and 34; signal peptide 272560016954 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 272560016955 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560016956 Pfam match to entry PF00419 Fimbrial, Fimbrial protein , score 83.4, E-value 3e-22 272560016957 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560016958 Signal peptide predicted for BPSS0096 by SignalP 2.0 HMM (Signal peptide probability 0.802) with cleavage site probability 0.294 between residues 28 and 29; signal peptide 272560016959 Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885 272560016960 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560016961 ligand binding site [chemical binding]; other site 272560016962 3 probable transmembrane helices predicted for BPSS0096 by TMHMM2.0 at aa 7-29, 33-52 and 332-354 272560016963 Pfam match to entry PF00691 OmpA, OmpA family , score 81.5, E-value 1.1e-21 272560016964 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3516 272560016965 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3517 272560016966 Protein of unknown function (DUF796); Region: DUF796; pfam05638 272560016967 Signal peptide predicted for BPSS0100 by SignalP 2.0 HMM (Signal peptide probability 0.913) with cleavage site probability 0.767 between residues 19 and 20; signal peptide 272560016968 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 272560016969 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016970 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3522 272560016971 hypothetical protein; Provisional; Region: PRK08126 272560016972 type IV / VI secretion system protein, DotU family; Region: IV_VI_DotU; TIGR03349 272560016973 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560016974 ligand binding site [chemical binding]; other site 272560016975 1 probable transmembrane helix predicted for BPSS0102 by TMHMM2.0 at aa 245-264 272560016976 Pfam match to entry PF00691 OmpA, OmpA family , score 96.9, E-value 2.6e-26 272560016977 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 272560016978 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560016979 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 272560016980 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560016981 5 probable transmembrane helices predicted for BPSS0103 by TMHMM2.0 at aa 12-34, 44-66, 73-91, 101-123 and 533-552 272560016982 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016983 PS00501 Signal peptidases I serine active site. 272560016984 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560016985 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560016986 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560016987 5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694 272560016988 PS00147 Arginase signature 1. 272560016989 Pseudogene. Similar to Salmonella typhi Rhs-family protein sty0321 SWALL:Q8Z953 (EMBL:AL627266) (1354 aa) fasta scores: E(): 7e-85, 33.22% id in 1222 aa, and to Yersinia pestis Rhs-like protein y0266 SWALL:AAM83860 (EMBL:AE013626) (963 aa) fasta scores: E(): 3.5e-63, 28.91% id in 875 aa. CDS contains a nonsense mutation (ochre) after codon 91; Rhs-like protein (pseudogene) 272560016990 PS00017 ATP/GTP-binding site motif A (P-loop). 272560016991 Glycosyltransferase (GlcNAc); Region: GlcNAc; pfam11397 272560016992 Signal peptide predicted for BPSS0109 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.812 between residues 23 and 24; signal peptide 272560016993 Fimbrial protein; Region: Fimbrial; pfam00419 272560016994 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 272560016995 ImpA-related N-terminal; Region: ImpA-rel_N; cl19907 272560016996 type VI secretion protein, VC_A0111 family; Region: VI_chp_1; TIGR03347 272560016997 Type VI protein secretion system component VasA [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3519 272560016998 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 272560016999 Protein of avirulence locus involved in temperature-dependent protein secretion [General function prediction only]; Region: ImpE; COG4455 272560017000 ImpE protein; Region: ImpE; pfam07024 272560017001 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560017002 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560017003 Walker A motif; other site 272560017004 ATP binding site [chemical binding]; other site 272560017005 Walker B motif; other site 272560017006 arginine finger; other site 272560017007 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560017008 Walker A motif; other site 272560017009 ATP binding site [chemical binding]; other site 272560017010 Walker B motif; other site 272560017011 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560017012 PS00213 Lipocalin signature. 272560017013 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 27.8, E-value 5.1e-07 272560017014 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017015 PS00870 Chaperonins clpA/B signature 1. 272560017016 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017017 hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841 272560017018 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560017019 dimer interface [polypeptide binding]; other site 272560017020 phosphorylation site [posttranslational modification] 272560017021 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560017022 ATP binding site [chemical binding]; other site 272560017023 Mg2+ binding site [ion binding]; other site 272560017024 G-X-G motif; other site 272560017025 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560017026 active site 272560017027 phosphorylation site [posttranslational modification] 272560017028 intermolecular recognition site; other site 272560017029 dimerization interface [polypeptide binding]; other site 272560017030 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 110.1, E-value 2.8e-30 272560017031 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 130.5, E-value 2e-36 272560017032 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 98.4, E-value 9.2e-27 272560017033 2 probable transmembrane helices predicted for BPSS0117 by TMHMM2.0 at aa 32-54 and 361-383 272560017034 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560017035 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560017036 active site 272560017037 phosphorylation site [posttranslational modification] 272560017038 intermolecular recognition site; other site 272560017039 dimerization interface [polypeptide binding]; other site 272560017040 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560017041 DNA binding residues [nucleotide binding] 272560017042 dimerization interface [polypeptide binding]; other site 272560017043 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 77.6, E-value 1.7e-20 272560017044 PS00622 Bacterial regulatory proteins, luxR family signature. 272560017045 Predicted helix-turn-helix motif with score 1137.000, SD 3.06 at aa 169-190, sequence LSVNEIANRLKRSKQTISSQKA 272560017046 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 82.7, E-value 4.9e-22 272560017047 P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188 272560017048 Signal peptide predicted for BPSS0120 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.520 between residues 34 and 35; signal peptide 272560017049 PapC N-terminal domain; Region: PapC_N; pfam13954 272560017050 Outer membrane usher protein; Region: Usher; pfam00577 272560017051 PapC C-terminal domain; Region: PapC_C; pfam13953 272560017052 Pfam match to entry PF00577 Usher, Fimbrial Usher protein , score 159.6, E-value 3.5e-45 272560017053 PS01151 Fimbrial biogenesis outer membrane usher protein signature. 272560017054 Signal peptide predicted for BPSS0121 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 33 and 34; signal peptide 272560017055 putative fimbrial chaperone protein; Provisional; Region: PRK09918 272560017056 Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345 272560017057 Pfam match to entry PF00345 pili_assembly, Gram-negative pili assembly chaperone, N-terminal domain , score 34.5, E-value 5.6e-10 272560017058 Signal peptide predicted for BPSS0122 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.973 between residues 24 and 25; signal peptide 272560017059 Protein of unknown function (DUF1120); Region: DUF1120; cl05856 272560017060 Signal peptide predicted for BPSS0123 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 36 and 37; signal peptide 272560017061 Protein of unknown function (DUF1120); Region: DUF1120; cl05856 272560017062 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560017063 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560017064 active site 272560017065 phosphorylation site [posttranslational modification] 272560017066 intermolecular recognition site; other site 272560017067 dimerization interface [polypeptide binding]; other site 272560017068 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560017069 DNA binding residues [nucleotide binding] 272560017070 dimerization interface [polypeptide binding]; other site 272560017071 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 82.4, E-value 6.2e-22 272560017072 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 59.4, E-value 5.2e-15 272560017073 H-NS histone family; Region: Histone_HNS; pfam00816 272560017074 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560017075 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 272560017076 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560017077 putative substrate translocation pore; other site 272560017078 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -90.8, E-value 0.00012 272560017079 12 probable transmembrane helices predicted for BPSS0126 by TMHMM2.0 at aa 23-40, 63-85, 92-111, 117-139, 152-174, 187-209, 261-283, 293-312, 324-341, 346-368, 373-395 and 415-432 272560017080 PS00107 Protein kinases ATP-binding region signature. 272560017081 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017082 Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929 272560017083 Pfam match to entry PF02595 DUF168, Uncharacterized BCR, COG1929 , score 650.6, E-value 5.3e-193 272560017084 pyruvate kinase; Provisional; Region: PRK06247 272560017085 Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288 272560017086 domain interfaces; other site 272560017087 active site 272560017088 Pfam match to entry PF00224 PK, Pyruvate kinase, barrel domain , score 472.9, E-value 1.6e-139 272560017089 PS00110 Pyruvate kinase active site signature. 272560017090 Pfam match to entry PF02887 PK_C, Pyruvate kinase, alpha/beta domain , score 40.1, E-value 3.4e-09 272560017091 Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835 272560017092 Putative sugar diacid recognition; Region: Diacid_rec; pfam05651 272560017093 PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556 272560017094 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 26.5, E-value 8.2e-07 272560017095 Predicted helix-turn-helix motif with score 1256.000, SD 3.46 at aa 368-389, sequence GHPSATAQALGIHRNTLDYRLQ 272560017096 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 272560017097 The adenylation domain (A domain) of a family of nonribosomal peptide synthetases (NRPSs) synthesizing toxins and antitumor agents; Region: A_NRPS_TubE_like; cd05906 272560017098 acyl-activating enzyme (AAE) consensus motif; other site 272560017099 putative AMP binding site [chemical binding]; other site 272560017100 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560017101 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560017102 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 272560017103 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 288.3, E-value 6.1e-84 272560017104 PS00455 AMP-binding domain signature. 272560017105 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 40.8, E-value 2e-09 272560017106 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 82.5, E-value 5.6e-22 272560017107 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560017108 extended (e) SDRs; Region: SDR_e; cd08946 272560017109 NAD(P) binding site [chemical binding]; other site 272560017110 active site 272560017111 substrate binding site [chemical binding]; other site 272560017112 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560017113 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560017114 O-methyltransferase; Region: Methyltransf_2; pfam00891 272560017115 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560017116 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560017117 S-adenosylmethionine binding site [chemical binding]; other site 272560017118 Pfam match to entry PF00891 Methyltransf_2, O-methyltransferase , score 203.3, E-value 2.4e-58 272560017119 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560017120 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017121 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560017122 dimerization interface [polypeptide binding]; other site 272560017123 substrate binding pocket [chemical binding]; other site 272560017124 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 106.9, E-value 2.6e-29 272560017125 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 79.2, E-value 5.6e-21 272560017126 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017127 Predicted helix-turn-helix motif with score 1665.000, SD 4.86 at aa 42-63, sequence GSLSKAAAHLCRTQGAVSRQIQ 272560017128 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560017129 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560017130 metal binding site [ion binding]; metal-binding site 272560017131 active site 272560017132 I-site; other site 272560017133 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 223.3, E-value 2.3e-64 272560017134 8 probable transmembrane helices predicted for BPSS0136 by TMHMM2.0 at aa 12-34, 44-66, 79-101, 116-135, 148-170, 190-212, 219-241 and 256-278 272560017135 Signal peptide predicted for BPSS0137 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 46 and 47; signal peptide 272560017136 1 probable transmembrane helix predicted for BPSS0138 by TMHMM2.0 at aa 29-51 272560017137 mercuric reductase; Validated; Region: PRK06370 272560017138 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560017139 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560017140 Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852 272560017141 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 232.8, E-value 3.1e-67 272560017142 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272560017143 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain , score 91.8, E-value 8.9e-25 272560017144 Signal peptide predicted for BPSS0140 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 26 and 27; signal peptide 272560017145 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_11; cd06321 272560017146 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560017147 putative ligand binding site [chemical binding]; other site 272560017148 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -4.6, E-value 3e-05 272560017149 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017150 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560017151 TM-ABC transporter signature motif; other site 272560017152 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -20.3, E-value 9.1e-06 272560017153 9 probable transmembrane helices predicted for BPSS0141 by TMHMM2.0 at aa 35-57, 67-89, 94-116, 120-142, 147-164, 184-206, 237-259, 274-305 and 310-332 272560017154 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 272560017155 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560017156 Walker A/P-loop; other site 272560017157 ATP binding site [chemical binding]; other site 272560017158 Q-loop/lid; other site 272560017159 ABC transporter signature motif; other site 272560017160 Walker B; other site 272560017161 D-loop; other site 272560017162 H-loop/switch region; other site 272560017163 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560017164 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 109.1, E-value 5.6e-30 272560017165 PS00211 ABC transporters family signature. 272560017166 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 189.9, E-value 2.7e-54 272560017167 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017168 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 272560017169 Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940 272560017170 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012 272560017171 Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037 272560017172 Pfam match to entry PF00480 ROK, ROK family , score 23.7, E-value 2.8e-08 272560017173 Predicted helix-turn-helix motif with score 998.000, SD 2.59 at aa 33-54, sequence ASKADLARLANLTGTAVGSIIA 272560017174 Signal peptide predicted for BPSS0144 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.422 between residues 22 and 23; signal peptide 272560017175 Glycoside hydrolase family 15, N-terminal domain; Region: GH15_N; cd07430 272560017176 Domain interface; other site 272560017177 glucan 1,4-alpha-glucosidase; Region: glucan_glucosid; TIGR01535 272560017178 Glycosyl hydrolases family 15; Region: Glyco_hydro_15; pfam00723 272560017179 Alpha-amylase, C-terminal CBM20 (carbohydrate-binding module, family 20) domain. This domain is found in several bacterial and fungal alpha-amylases including the maltopentaose-forming amylases (G5-amylases). Most alpha-amylases have, in addition to the...; Region: CBM20_alpha_amylase; cd05808 272560017180 starch-binding site 2 [chemical binding]; other site 272560017181 starch-binding site 1 [chemical binding]; other site 272560017182 Pfam match to entry PF00686 CBM_20, Starch binding domain , score 118.9, E-value 6.2e-33 272560017183 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 272560017184 ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776 272560017185 DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif; Region: DEADc; cd00268 272560017186 ATP binding site [chemical binding]; other site 272560017187 Mg++ binding site [ion binding]; other site 272560017188 motif III; other site 272560017189 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560017190 nucleotide binding region [chemical binding]; other site 272560017191 ATP-binding site [chemical binding]; other site 272560017192 RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501 272560017193 putative RNA binding site [nucleotide binding]; other site 272560017194 Pfam match to entry PF03880 DbpA, DbpA RNA binding domain , score 108.4, E-value 9e-30 272560017195 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 108.5, E-value 8.5e-30 272560017196 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 265.3, E-value 5.4e-77 272560017197 PS00039 DEAD-box subfamily ATP-dependent helicases signature. 272560017198 PS01070 DNA/RNA non-specific endonucleases active site. 272560017199 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017200 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560017201 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560017202 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560017203 putative substrate translocation pore; other site 272560017204 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 80.2, E-value 2.8e-21 272560017205 12 probable transmembrane helices predicted for BPSS0147 by TMHMM2.0 at aa 46-68, 88-110, 123-145, 150-172, 193-215, 220-237, 272-294, 304-326, 338-356, 366-388, 401-423 and 433-450 272560017206 PS00217 Sugar transport proteins signature 2. 272560017207 PS00216 Sugar transport proteins signature 1. 272560017208 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 272560017209 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 272560017210 metal binding site [ion binding]; metal-binding site 272560017211 putative dimer interface [polypeptide binding]; other site 272560017212 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 291.7, E-value 5.8e-85 272560017213 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 272560017214 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017215 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560017216 dimerization interface [polypeptide binding]; other site 272560017217 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 90.5, E-value 2.2e-24 272560017218 Predicted helix-turn-helix motif with score 1745.000, SD 5.13 at aa 16-37, sequence GSIRAAARRLNVSPAALTKAVK 272560017219 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017220 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 123.7, E-value 2.2e-34 272560017221 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560017222 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560017223 Fatty acid desaturase protein family subgroup, a delta-12 acyl-lipid desaturase-like, DesA-like, yet uncharacterized subgroup of membrane fatty acid desaturase proteins found in alpha-, beta-, and gamma-proteobacteria. Sequences of this domain family...; Region: DesA_FADS-like; cd03509 272560017224 putative di-iron ligands [ion binding]; other site 272560017225 1 probable transmembrane helix predicted for BPSS0151 by TMHMM2.0 at aa 107-129 272560017226 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 20.6, E-value 3.6e-07 272560017227 Signal peptide predicted for BPSS0152 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 24 and 25; signal peptide 272560017228 4 probable transmembrane helices predicted for BPSS0152 by TMHMM2.0 at aa 5-25, 40-62, 75-97 and 102-119 272560017229 Signal peptide predicted for BPSS0153 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 23 and 24; signal peptide 272560017230 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560017231 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560017232 substrate binding pocket [chemical binding]; other site 272560017233 membrane-bound complex binding site; other site 272560017234 hinge residues; other site 272560017235 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 202.5, E-value 4.4e-58 272560017236 D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711 272560017237 NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126 272560017238 Signal peptide predicted for BPSS0154 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.975 between residues 20 and 21; signal peptide 272560017239 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560017240 Pfam match to entry PF03721 UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain , score 31.7, E-value 4.2e-08 272560017241 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560017242 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017243 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560017244 dimerization interface [polypeptide binding]; other site 272560017245 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 100.5, E-value 2.1e-27 272560017246 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 77.4, E-value 1.9e-20 272560017247 Predicted helix-turn-helix motif with score 2048.000, SD 6.16 at aa 16-37, sequence GSLSKAAQLLCVSQPAVSKVLA 272560017248 short chain dehydrogenase; Provisional; Region: PRK07023 272560017249 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 272560017250 NAD(P) binding site [chemical binding]; other site 272560017251 active site 272560017252 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 42.1, E-value 5e-10 272560017253 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560017254 Signal peptide predicted for BPSS0158 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 59 and 60; signal peptide 272560017255 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 272560017256 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017257 Signal peptide predicted for BPSS0159 by SignalP 2.0 HMM (Signal peptide probability 0.943) with cleavage site probability 0.438 between residues 19 and 20; signal peptide 272560017258 Putative alpha-1,2-mannosidase [Carbohydrate transport and metabolism]; Region: COG3537 272560017259 Glycosyl hydrolase family 92; Region: Glyco_hydro_92; pfam07971 272560017260 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560017261 Pyoverdine/dityrosine biosynthesis protein; Region: DIT1_PvcA; pfam05141 272560017262 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560017263 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 272560017264 substrate binding pocket [chemical binding]; other site 272560017265 active site 272560017266 iron coordination sites [ion binding]; other site 272560017267 Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368 272560017268 4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241 272560017269 Pfam match to entry PF03241 HpaB, 4-hydroxyphenylacetate 3-hydroxylase , score 598.7, E-value 2.3e-177 272560017270 Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712 272560017271 active site 272560017272 asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536 272560017273 dimer interface [polypeptide binding]; other site 272560017274 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 272560017275 Ligand Binding Site [chemical binding]; other site 272560017276 Molecular Tunnel; other site 272560017277 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 52.0, E-value 8.3e-13 272560017278 Pfam match to entry PF00733 Asn_synthase, Asparagine synthase , score 109.8, E-value 3.5e-30 272560017279 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 272560017280 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 272560017281 NADP binding site [chemical binding]; other site 272560017282 dimer interface [polypeptide binding]; other site 272560017283 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 272.7, E-value 3.1e-79 272560017284 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 272560017285 The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370 272560017286 putative active site [active] 272560017287 putative metal binding site [ion binding]; other site 272560017288 Pfam match to entry PF02900 LigB, Catalytic LigB subunit of aromatic ring-opening dioxygenase , score 38.2, E-value 3.8e-11 272560017289 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560017290 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017291 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560017292 putative effector binding pocket; other site 272560017293 dimerization interface [polypeptide binding]; other site 272560017294 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 129.8, E-value 3.3e-36 272560017295 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 82.7, E-value 4.9e-22 272560017296 Predicted helix-turn-helix motif with score 1341.000, SD 3.75 at aa 30-51, sequence GSFTAAAECLSMSKSLVSEYLS 272560017297 Signal peptide predicted for BPSS0167 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.837 between residues 36 and 37; signal peptide 272560017298 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 272560017299 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560017300 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 272560017301 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560017302 5 probable transmembrane helices predicted for BPSS0167 by TMHMM2.0 at aa 13-35, 40-62, 69-91, 101-120 and 577-599 272560017303 PS00046 Histone H2A signature. 272560017304 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017305 hypothetical protein; Provisional; Region: PRK08126 272560017306 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560017307 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560017308 ligand binding site [chemical binding]; other site 272560017309 Pfam match to entry PF00691 OmpA, OmpA family , score 111.1, E-value 1.4e-30 272560017310 1 probable transmembrane helix predicted for BPSS0168 by TMHMM2.0 at aa 234-256 272560017311 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 272560017312 Signal peptide predicted for BPSS0170 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.290 between residues 26 and 27; signal peptide 272560017313 Type VI secretion lipoprotein; Region: T6SS-SciN; cl01405 272560017314 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017315 Protein of unknown function (DUF796); Region: DUF796; pfam05638 272560017316 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3517 272560017317 PS00237 G-protein coupled receptors signature. 272560017318 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3516 272560017319 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560017320 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560017321 Walker A motif; other site 272560017322 ATP binding site [chemical binding]; other site 272560017323 Walker B motif; other site 272560017324 arginine finger; other site 272560017325 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560017326 Walker A motif; other site 272560017327 ATP binding site [chemical binding]; other site 272560017328 Walker B motif; other site 272560017329 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560017330 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017331 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 29.8, E-value 3.5e-07 272560017332 PS00870 Chaperonins clpA/B signature 1. 272560017333 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017334 PS00213 Lipocalin signature. 272560017335 ImpE protein; Region: ImpE; pfam07024 272560017336 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 272560017337 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 272560017338 type VI secretion protein, VC_A0111 family; Region: VI_chp_1; TIGR03347 272560017339 Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport]; Region: COG3515 272560017340 ImpA-related N-terminal; Region: ImpA-rel_N; cl19907 272560017341 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560017342 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560017343 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560017344 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; pfam09937 272560017345 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017346 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017347 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 272560017348 Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576 272560017349 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017350 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017351 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 50.2, E-value 2.9e-12 272560017352 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 39.8, E-value 4.1e-09 272560017353 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 12.1, E-value 0.023 272560017354 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 37.0, E-value 2.8e-08 272560017355 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 46.2, E-value 4.9e-11 272560017356 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 272560017357 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017358 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560017359 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 17.4, E-value 0.0065 272560017360 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 4.9, E-value 0.14 272560017361 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 15.4, E-value 0.01 272560017362 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 31.3, E-value 1.5e-06 272560017363 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 22.8, E-value 0.00053 272560017364 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 42.4, E-value 6.9e-10 272560017365 Protein of unknown function (DUF3540); Region: DUF3540; pfam12059 272560017366 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 272560017367 Signal peptide predicted for BPSS0186 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 24 and 25; signal peptide 272560017368 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 272560017369 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560017370 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017371 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to DntR, which is involved in the catabolism of dinitrotoluene; contains the type 2 periplasmic binding fold; Region: PBP2_DntR_like_3; cd08461 272560017372 putative substrate binding pocket [chemical binding]; other site 272560017373 putative dimerization interface [polypeptide binding]; other site 272560017374 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 132.2, E-value 6.1e-37 272560017375 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 70.5, E-value 2.3e-18 272560017376 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017377 Predicted helix-turn-helix motif with score 1554.000, SD 4.48 at aa 22-43, sequence HNVTRAAARLNLSQPSVSIHLA 272560017378 Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249 272560017379 Pfam match to entry PF02525 Flavodoxin_2, Flavodoxin-like fold , score 308.2, E-value 6.5e-90 272560017380 Gene remnant. Similar to the C-terminal region of Streptomyces coelicolor AraC-family transcriptional regulator sco0605 or scf55.29 SWALL:Q9RJN9 (EMBL:AL939106) (311 aa) fasta scores: E(): 3e-22, 54.86% id in 144 aa, and of Mycobacterium smegmatis transcription activator SWALL:Q938B5 (EMBL:AY054120) (332 aa) fasta scores: E(): 1.2e-19, 47.26% id in 146 aa. CDS lacks an appropriate translational start codon; AraC-family transcriptional regulator (fragment) 272560017381 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.2, E-value 1.9e-07 272560017382 Predicted helix-turn-helix motif with score 1127.000, SD 3.03 at aa 40-61, sequence STRDAIARQSAMSVRTLARRFQ 272560017383 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 16.0, E-value 0.049 272560017384 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 272560017385 homodimer interface [polypeptide binding]; other site 272560017386 substrate-cofactor binding pocket; other site 272560017387 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560017388 catalytic residue [active] 272560017389 Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme , score 686.0, E-value 1.2e-203 272560017390 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245 272560017391 dimer interface [polypeptide binding]; other site 272560017392 putative metal binding site [ion binding]; other site 272560017393 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 28.0, E-value 7e-08 272560017394 Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456 272560017395 12 probable transmembrane helices predicted for BPSS0193 by TMHMM2.0 at aa 29-51, 61-83, 95-117, 137-159, 166-188, 203-220, 241-263, 273-295, 327-346, 352-374, 391-413 and 417-439 272560017396 Allophanate hydrolase subunit 2; Region: AHS2; smart00797 272560017397 Pfam match to entry PF02626 DUF183, Uncharacterized ACR, COG1984 , score 287.8, E-value 8.9e-84 272560017398 Allophanate hydrolase subunit 1; Region: AHS1; smart00796 272560017399 Pfam match to entry PF02682 DUF213, Uncharacterized ACR, COG2049 , score -1.6, E-value 3.6e-09 272560017400 acetyl-CoA carboxylase biotin carboxylase subunit; Provisional; Region: PRK12833 272560017401 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560017402 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560017403 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785 272560017404 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain , score 204.5, E-value 1e-58 272560017405 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 346.4, E-value 2.1e-101 272560017406 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560017407 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560017408 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 153.0, E-value 3.4e-43 272560017409 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 272560017410 carboxyltransferase (CT) interaction site; other site 272560017411 biotinylation site [posttranslational modification]; other site 272560017412 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 72.6, E-value 5.5e-19 272560017413 uncharacterized proteins similar to the Aspergillus nidulans lactam utilization protein LamB; Region: LamB_YcsF_like_2; cd11664 272560017414 putative active site [active] 272560017415 Pfam match to entry PF03746 LamB_YcsF, LamB/YcsF family , score 437.8, E-value 6.2e-129 272560017416 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560017417 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017418 The C-terminal substrate-binding domain of putative LysR-type transcriptional regulator PAO1-like, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_PAO1_like; cd08412 272560017419 putative substrate binding pocket [chemical binding]; other site 272560017420 dimerization interface [polypeptide binding]; other site 272560017421 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 87.4, E-value 1.9e-23 272560017422 Predicted helix-turn-helix motif with score 1374.000, SD 3.87 at aa 18-39, sequence GQISQAAIQLTISQSAVTSAIR 272560017423 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017424 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 161.7, E-value 8.2e-46 272560017425 Signal peptide predicted for BPSS0200 by SignalP 2.0 HMM (Signal peptide probability 0.980) with cleavage site probability 0.707 between residues 33 and 34; signal peptide 272560017426 Penicillin amidase; Region: Penicil_amidase; pfam01804 272560017427 Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747 272560017428 active site 272560017429 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017430 Pfam match to entry PF01804 Penicil_amidase, Penicillin amidase , score 495.7, E-value 2.4e-146 272560017431 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560017432 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560017433 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 89.9, E-value 3.2e-24 272560017434 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560017435 S-adenosylmethionine binding site [chemical binding]; other site 272560017436 Signal peptide predicted for BPSS0203 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.407 between residues 40 and 41; signal peptide 272560017437 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017438 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560017439 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560017440 dimerization interface [polypeptide binding]; other site 272560017441 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560017442 dimer interface [polypeptide binding]; other site 272560017443 putative CheW interface [polypeptide binding]; other site 272560017444 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 350.5, E-value 1.2e-102 272560017445 Pfam match to entry PF00672 HAMP, HAMP domain , score 57.7, E-value 1.7e-14 272560017446 1 probable transmembrane helix predicted for BPSS0204 by TMHMM2.0 at aa 28-50 272560017447 propionate catabolism operon regulatory protein PrpR; Region: propionate_PrpR; TIGR02329 272560017448 Propionate catabolism activator; Region: PrpR_N; pfam06506 272560017449 PAS fold; Region: PAS; pfam00989 272560017450 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560017451 putative active site [active] 272560017452 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560017453 Walker A motif; other site 272560017454 ATP binding site [chemical binding]; other site 272560017455 Walker B motif; other site 272560017456 arginine finger; other site 272560017457 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560017458 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 42.3, E-value 7e-10 272560017459 Predicted helix-turn-helix motif with score 1005.000, SD 2.61 at aa 648-669, sequence GDRDRACARLGISKTTLWRKLA 272560017460 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560017461 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 427.0, E-value 1.1e-125 272560017462 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560017463 Pfam match to entry PF00989 PAS, PAS domain , score 26.8, E-value 5.5e-07 272560017464 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 272560017465 tetramer interface [polypeptide binding]; other site 272560017466 active site 272560017467 Mg2+/Mn2+ binding site [ion binding]; other site 272560017468 Pfam match to entry PF00463 ICL, Isocitrate lyase , score 26.5, E-value 6.2e-12 272560017469 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 272560017470 Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117 272560017471 dimer interface [polypeptide binding]; other site 272560017472 active site 272560017473 citrylCoA binding site [chemical binding]; other site 272560017474 oxalacetate/citrate binding site [chemical binding]; other site 272560017475 coenzyme A binding site [chemical binding]; other site 272560017476 catalytic triad [active] 272560017477 Pfam match to entry PF00285 citrate_synt, Citrate synthase , score 331.7, E-value 5.6e-97 272560017478 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017479 PS00480 Citrate synthase signature. 272560017480 2-methylisocitrate dehydratase, Fe/S-dependent; Region: 2met_isocit_dHY; TIGR02333 272560017481 Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285 272560017482 substrate binding site [chemical binding]; other site 272560017483 ligand binding site [chemical binding]; other site 272560017484 Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215 272560017485 substrate binding site [chemical binding]; other site 272560017486 Pfam match to entry PF00330 aconitase, Aconitase (aconitate hydratase) , score 543.3, E-value 1.1e-160 272560017487 Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain , score 114.6, E-value 1.2e-31 272560017488 PrpF protein; Region: PrpF; cl19418 272560017489 1 probable transmembrane helix predicted for BPSS0209 by TMHMM2.0 at aa 318-340 272560017490 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560017491 CoenzymeA binding site [chemical binding]; other site 272560017492 subunit interaction site [polypeptide binding]; other site 272560017493 PHB binding site; other site 272560017494 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 76.1, E-value 4.7e-20 272560017495 Domain of unknown function (DUF1843); Region: DUF1843; pfam08898 272560017496 Domain of unknown function (DUF1842); Region: DUF1842; pfam08896 272560017497 Domain of unknown function (DUF1843); Region: DUF1843; pfam08898 272560017498 Domain of unknown function (DUF1842); Region: DUF1842; pfam08896 272560017499 Domain of unknown function (DUF1843); Region: DUF1843; pfam08898 272560017500 Y_X(10)_GDL-associated radical SAM protein; Region: rad_SAM_trio; TIGR03913 272560017501 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560017502 FeS/SAM binding site; other site 272560017503 radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085 272560017504 Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / nifB / pqqE family , score 68.6, E-value 8.3e-18 272560017505 methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048 272560017506 Signal peptide predicted for BPSS0215 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.770 between residues 24 and 25; signal peptide 272560017507 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 272560017508 dimer interface [polypeptide binding]; other site 272560017509 ligand binding site [chemical binding]; other site 272560017510 HAMP domain; Region: HAMP; pfam00672 272560017511 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560017512 dimer interface [polypeptide binding]; other site 272560017513 putative CheW interface [polypeptide binding]; other site 272560017514 2 probable transmembrane helices predicted for BPSS0215 by TMHMM2.0 at aa 10-32 and 186-208 272560017515 Pfam match to entry PF02203 TarH, Tar ligand binding domain homologue , score 45.1, E-value 1e-10 272560017516 PS00097 Aspartate and ornithine carbamoyltransferases signature. 272560017517 Pfam match to entry PF00672 HAMP, HAMP domain , score 37.9, E-value 1.5e-08 272560017518 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 343.0, E-value 2.2e-100 272560017519 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560017520 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560017521 putative substrate translocation pore; other site 272560017522 13 probable transmembrane helices predicted for BPSS0216 by TMHMM2.0 at aa 85-107, 114-136, 141-163, 175-197, 202-224, 237-255, 260-282, 303-325, 340-362, 369-388, 393-412, 439-461 and 515-537 272560017523 PS00216 Sugar transport proteins signature 1. 272560017524 DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986 272560017525 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017526 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414 272560017527 dimerization interface [polypeptide binding]; other site 272560017528 substrate binding pocket [chemical binding]; other site 272560017529 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 70.3, E-value 2.6e-18 272560017530 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560017531 Predicted helix-turn-helix motif with score 1289.000, SD 3.58 at aa 29-50, sequence LHFARAADELDIAPPALTRLVQ 272560017532 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 100.2, E-value 2.7e-27 272560017533 dimerization interface [polypeptide binding]; other site 272560017534 AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cl00183 272560017535 putative active cleft [active] 272560017536 Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285 272560017537 MgtC family; Region: MgtC; pfam02308 272560017538 4 probable transmembrane helices predicted for BPSS0219 by TMHMM2.0 at aa 13-35, 50-72, 84-106 and 121-143 272560017539 Pfam match to entry PF02308 MgtC, MgtC family , score 181.9, E-value 6.7e-52 272560017540 1 probable transmembrane helix predicted for BPSS0220 by TMHMM2.0 at aa 338-360 272560017541 Acetyltransferases [General function prediction only]; Region: RimI; COG0456 272560017542 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560017543 Coenzyme A binding pocket [chemical binding]; other site 272560017544 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 64.8, E-value 1.2e-16 272560017545 Protein of unknown function (DUF4087); Region: DUF4087; pfam13316 272560017546 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 272560017547 metal-binding site [ion binding] 272560017548 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 272560017549 metal-binding site [ion binding] 272560017550 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217 272560017551 Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371 272560017552 metal-binding site [ion binding] 272560017553 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560017554 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560017555 motif II; other site 272560017556 8 probable transmembrane helices predicted for BPSS0224 by TMHMM2.0 at aa 330-352, 356-378, 390-412, 417-436, 573-595, 605-627, 926-945 and 949-968 272560017557 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 110.4, E-value 2.2e-30 272560017558 PS01229 Hypothetical cof family signature 2. 272560017559 PS00154 E1-E2 ATPases phosphorylation site. 272560017560 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 323.2, E-value 2e-94 272560017561 Pfam match to entry PF00403 HMA, Heavy-metal-associated domain , score 94.5, E-value 1.4e-25 272560017562 PS01047 Heavy-metal-associated domain. 272560017563 Pfam match to entry PF00403 HMA, Heavy-metal-associated domain , score 74.5, E-value 1.5e-19 272560017564 PS01047 Heavy-metal-associated domain. 272560017565 Pfam match to entry PF00403 HMA, Heavy-metal-associated domain , score 74.8, E-value 1.1e-19 272560017566 PS01047 Heavy-metal-associated domain. 272560017567 Signal peptide predicted for BPSS0225 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.628 between residues 26 and 27; signal peptide 272560017568 Protein of unknown function (DUF1311); Region: DUF1311; pfam07007 272560017569 Signal peptide predicted for BPSS0226 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.231 between residues 27 and 28; signal peptide 272560017570 Uncharacterized conserved protein [Function unknown]; Region: COG5361 272560017571 Protein of unknown function (DUF1254); Region: DUF1254; pfam06863 272560017572 Protein of unknown function (DUF1214); Region: DUF1214; cl08447 272560017573 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017574 AsmA family; Region: AsmA; pfam05170 272560017575 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 272560017576 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 272560017577 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 272560017578 Domain of Unknown Function (DUF748); Region: DUF748; pfam05359 272560017579 1 probable transmembrane helix predicted for BPSS0227 by TMHMM2.0 at aa 59-81 272560017580 Signal peptide predicted for BPSS0229 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.900 between residues 39 and 40; signal peptide 272560017581 Sulfatase; Region: Sulfatase; cl19157 272560017582 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 272560017583 active site 272560017584 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 42.0, E-value 8.8e-10 272560017585 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 272560017586 active site lid residues [active] 272560017587 substrate binding pocket [chemical binding]; other site 272560017588 catalytic residues [active] 272560017589 substrate-Mg2+ binding site; other site 272560017590 aspartate-rich region 1; other site 272560017591 aspartate-rich region 2; other site 272560017592 Pfam match to entry PF00494 SQS_PSY, Squalene/phytoene synthase , score 27.3, E-value 4.2e-13 272560017593 PS00018 EF-hand calcium-binding domain. 272560017594 Probable gene rement. Similar to the C-terminal regions of Bordetella pertussis probable LysR-family transcriptional regulator bp1607 SWALL:Q7VXW7 (EMBL:BX640415) (300 aa) fasta scores: E(): 3.4e-41, 62.98% id in 181 aa, and Ralstonia solanacearum probable transcription regulator protein rsc1152 or rs04599 SWALL:Q8Y092 (EMBL:AL646063) (297 aa) fasta scores: E(): 5.8e-37, 59.66% id in 181 aa. CDS contains several framshift mutations;LysR-family regulatory protein (fragment) 272560017595 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 47.4, E-value 6.8e-13 272560017596 Similar to Chromobacterium violaceum hypothetical protein cv0784 SWALL:Q7NZY5 (EMBL:AE016912) (62 aa) fasta scores: E(): 1.1e-20, 82.25% id in 62 aa, and to Bordetella bronchiseptica membrane protein bb2409 SWALL:Q7WJT4 (EMBL:BX640444) (64 aa) fasta scores: E(): 1.1e-18, 74.6% id in 63 aa. CDS contains a nonsense mutation (opal) after codon 10; membrane protein (pseudogene) 272560017597 Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294 272560017598 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 272560017599 Pfam match to entry PF02322 Cyto_ox_2, Cytochrome oxidase subunit II , score 465.2, E-value 3.4e-137 272560017600 8 probable transmembrane helices predicted for BPSS0234 by TMHMM2.0 at aa 13-35, 72-94, 114-136, 156-178, 191-210, 225-244, 257-279 and 299-321 272560017601 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654 272560017602 Pfam match to entry PF01654 Bac_Ubq_Cox, Bacterial Cytochrome Ubiquinol Oxidase , score 718.0, E-value 2.8e-213 272560017603 9 probable transmembrane helices predicted for BPSS0235 by TMHMM2.0 at aa 15-37, 57-79, 99-121, 128-150, 187-209, 222-239, 323-345, 357-379 and 408-430 272560017604 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560017605 Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212 272560017606 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560017607 catalytic residue [active] 272560017608 chromosome replication initiation inhibitor protein; Provisional; Region: PRK13348 272560017609 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017610 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560017611 dimerization interface [polypeptide binding]; other site 272560017612 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 69.2, E-value 5.8e-18 272560017613 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017614 Predicted helix-turn-helix motif with score 1497.000, SD 4.29 at aa 27-48, sequence GSFEQAAARLHVTASAVTQRVR 272560017615 Transglycosylase; Region: Transgly; pfam00912 272560017616 penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074 272560017617 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560017618 1 probable transmembrane helix predicted for BPSS0238 by TMHMM2.0 at aa 38-57 272560017619 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 300.6, E-value 1.2e-87 272560017620 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 64.6, E-value 1.4e-16 272560017621 Predicted membrane protein [Function unknown]; Region: COG2860 272560017622 UPF0126 domain; Region: UPF0126; pfam03458 272560017623 UPF0126 domain; Region: UPF0126; pfam03458 272560017624 Pfam match to entry PF03458 UPF0126, UPF0126 domain , score 99.2, E-value 5.2e-27 272560017625 7 probable transmembrane helices predicted for BPSS0239 by TMHMM2.0 at aa 4-21, 28-47, 62-81, 86-108, 112-134, 146-165 and 170-187 272560017626 Pfam match to entry PF03458 UPF0126, UPF0126 domain , score 86.9, E-value 2.7e-23 272560017627 hmu cluster 272560017628 hemin importer ATP-binding subunit; Provisional; Region: hmuV; PRK13547 272560017629 ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214 272560017630 Walker A/P-loop; other site 272560017631 ATP binding site [chemical binding]; other site 272560017632 Q-loop/lid; other site 272560017633 ABC transporter signature motif; other site 272560017634 Walker B; other site 272560017635 D-loop; other site 272560017636 H-loop/switch region; other site 272560017637 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 141.9, E-value 7.2e-40 272560017638 PS00211 ABC transporters family signature. 272560017639 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017640 Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550 272560017641 ABC-ATPase subunit interface; other site 272560017642 dimer interface [polypeptide binding]; other site 272560017643 putative PBP binding regions; other site 272560017644 Pfam match to entry PF01032 FecCD, FecCD transport family , score 310.3, E-value 1.5e-90 272560017645 9 probable transmembrane helices predicted for BPSS0241 by TMHMM2.0 at aa 38-60, 97-119, 126-148, 152-174, 186-208, 228-247, 279-301, 316-333 and 346-365 272560017646 Signal peptide predicted for BPSS0242 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.843 between residues 32 and 33; signal peptide 272560017647 Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+. Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262 272560017648 Periplasmic binding protein; Region: Peripla_BP_2; pfam01497 272560017649 intersubunit interface [polypeptide binding]; other site 272560017650 Pfam match to entry PF01497 Peripla_BP_2, Periplasmic binding protein , score 128.7, E-value 6.7e-36 272560017651 1 probable transmembrane helix predicted for BPSS0242 by TMHMM2.0 at aa 13-32 272560017652 Putative heme degradation protein [Inorganic ion transport and metabolism]; Region: HemS; COG3720 272560017653 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 272560017654 Haemin-degrading HemS.ChuX domain; Region: HemS; pfam05171 272560017655 Signal peptide predicted for BPSS0244 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.852 between residues 23 and 24; signal peptide 272560017656 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 272560017657 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560017658 N-terminal plug; other site 272560017659 ligand-binding site [chemical binding]; other site 272560017660 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 63.9, E-value 2.3e-16 272560017661 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560017662 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017663 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560017664 dimerization interface [polypeptide binding]; other site 272560017665 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 117.2, E-value 2e-32 272560017666 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 87.5, E-value 1.7e-23 272560017667 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017668 Predicted helix-turn-helix motif with score 2037.000, SD 6.12 at aa 21-42, sequence LNFSYAARELGLTPSAVSRQIA 272560017669 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560017670 dimer interface [polypeptide binding]; other site 272560017671 conserved gate region; other site 272560017672 putative PBP binding loops; other site 272560017673 ABC-ATPase subunit interface; other site 272560017674 6 probable transmembrane helices predicted for BPSS0247 by TMHMM2.0 at aa 3-25, 45-67, 80-102, 107-129, 170-192 and 207-229 272560017675 PS00435 Peroxidases proximal heme-ligand signature. 272560017676 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 23.1, E-value 0.00032 272560017677 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 272560017678 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 272560017679 Walker A/P-loop; other site 272560017680 ATP binding site [chemical binding]; other site 272560017681 Q-loop/lid; other site 272560017682 ABC transporter signature motif; other site 272560017683 Walker B; other site 272560017684 D-loop; other site 272560017685 H-loop/switch region; other site 272560017686 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 229.2, E-value 3.9e-66 272560017687 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017688 PS00211 ABC transporters family signature. 272560017689 Signal peptide predicted for BPSS0249 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.894 between residues 41 and 42; signal peptide 272560017690 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 272560017691 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 45.7, E-value 6.9e-11 272560017692 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560017693 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560017694 dimer interface [polypeptide binding]; other site 272560017695 conserved gate region; other site 272560017696 putative PBP binding loops; other site 272560017697 ABC-ATPase subunit interface; other site 272560017698 6 probable transmembrane helices predicted for BPSS0250 by TMHMM2.0 at aa 21-43, 69-91, 103-125, 145-164, 213-235 and 255-277 272560017699 DNA recombination-mediator protein A; Region: DNA_processg_A; cl00695 272560017700 Pfam match to entry PF03641 Lysine_decarbox, Lysine decarboxylase , score 19.1, E-value 7.1e-06 272560017701 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560017702 trimer interface [polypeptide binding]; other site 272560017703 eyelet of channel; other site 272560017704 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -51.1, E-value 0.0003 272560017705 Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390 272560017706 Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412 272560017707 Putative sugar-binding domain; Region: Sugar-bind; pfam04198 272560017708 Predicted helix-turn-helix motif with score 1806.000, SD 5.34 at aa 18-39, sequence LTQEELAQKFAISRPKVGRLLK 272560017709 ribose-5-phosphate isomerase B; Provisional; Region: PRK05571 272560017710 Pfam match to entry PF02502 LacAB_rpiB, Ribose/Galactose Isomerase , score 163.1, E-value 3e-46 272560017711 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 272560017712 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560017713 Walker A/P-loop; other site 272560017714 ATP binding site [chemical binding]; other site 272560017715 Q-loop/lid; other site 272560017716 ABC transporter signature motif; other site 272560017717 Walker B; other site 272560017718 D-loop; other site 272560017719 H-loop/switch region; other site 272560017720 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560017721 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 157.1, E-value 2e-44 272560017722 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017723 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 113.8, E-value 2.1e-31 272560017724 PS00211 ABC transporters family signature. 272560017725 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560017726 TM-ABC transporter signature motif; other site 272560017727 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -45.1, E-value 0.00012 272560017728 8 probable transmembrane helices predicted for BPSS0256 by TMHMM2.0 at aa 29-51, 61-78, 83-102, 107-129, 136-153, 173-195, 224-246 and 280-302 272560017729 Signal peptide predicted for BPSS0257 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 32 and 33; signal peptide 272560017730 Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301 272560017731 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560017732 putative ligand binding site [chemical binding]; other site 272560017733 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -15.6, E-value 0.00015 272560017734 short chain dehydrogenase; Provisional; Region: PRK06841 272560017735 classical (c) SDRs; Region: SDR_c; cd05233 272560017736 NAD(P) binding site [chemical binding]; other site 272560017737 active site 272560017738 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 265.1, E-value 5.9e-77 272560017739 PS00061 Short-chain dehydrogenases/reductases family signature. 272560017740 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560017741 Alcohol dehydrogenases of the MDR family; Region: Zn_ADH2; cd08256 272560017742 putative NAD(P) binding site [chemical binding]; other site 272560017743 catalytic Zn binding site [ion binding]; other site 272560017744 structural Zn binding site [ion binding]; other site 272560017745 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 246.5, E-value 2.5e-71 272560017746 Dak1 domain; Region: Dak1; cl10557 272560017747 Pfam match to entry PF02733 Dak1, Dak1 domain , score 259.4, E-value 3.2e-75 272560017748 DAK2 domain; Region: Dak2; pfam02734 272560017749 Pfam match to entry PF02734 Dak2, DAK2 domain , score 97.4, E-value 1.8e-26 272560017750 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 51.3, E-value 1.3e-12 272560017751 2 probable transmembrane helices predicted for BPSS0263 by TMHMM2.0 at aa 66-85 and 89-106 272560017752 Protein of unknown function (DUF2866); Region: DUF2866; pfam11065 272560017753 Signal peptide predicted for BPSS0265 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21; signal peptide 272560017754 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560017755 trimer interface [polypeptide binding]; other site 272560017756 eyelet of channel; other site 272560017757 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -40.6, E-value 0.00012 272560017758 PS00572 Glycosyl hydrolases family 1 active site. 272560017759 ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464 272560017760 Signal peptide predicted for BPSS0266 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 23 and 24; signal peptide 272560017761 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein , score 401.9, E-value 4.1e-118 272560017762 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like subfamily; subgroup includes Pseudomonas aeruginosa AotO; Region: M14_PaAOTO_like; cd06250 272560017763 Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952 272560017764 active site 272560017765 Zn binding site [ion binding]; other site 272560017766 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560017767 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017768 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 150.9, E-value 1.5e-42 272560017769 10 probable transmembrane helices predicted for BPSS0268 by TMHMM2.0 at aa 51-73, 94-116, 126-148, 186-205, 210-232, 245-267, 271-293, 313-335, 345-362 and 379-401 272560017770 histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437 272560017771 Signal peptide predicted for BPSS0269 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 24 and 25; signal peptide 272560017772 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560017773 substrate binding pocket [chemical binding]; other site 272560017774 membrane-bound complex binding site; other site 272560017775 hinge residues; other site 272560017776 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 280.6, E-value 1.3e-81 272560017777 PS00017 ATP/GTP-binding site motif A (P-loop). 272560017778 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560017779 putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791 272560017780 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017781 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560017782 dimerization interface [polypeptide binding]; other site 272560017783 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 121.8, E-value 8.2e-34 272560017784 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 79.5, E-value 4.5e-21 272560017785 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017786 Predicted helix-turn-helix motif with score 1789.000, SD 5.28 at aa 16-37, sequence KSLRAAARALGVTQPAITHTIR 272560017787 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560017788 Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473 272560017789 M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666 272560017790 metal binding site [ion binding]; metal-binding site 272560017791 putative dimer interface [polypeptide binding]; other site 272560017792 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 283.6, E-value 1.6e-82 272560017793 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560017794 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560017795 putative substrate translocation pore; other site 272560017796 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 64.3, E-value 1.7e-16 272560017797 10 probable transmembrane helices predicted for BPSS0272 by TMHMM2.0 at aa 30-52, 67-89, 101-123, 198-217, 248-270, 285-307, 314-333, 343-365, 378-400 and 410-429 272560017798 pyrimidine utilization regulatory protein R; Region: RutR; TIGR03613 272560017799 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560017800 YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362 272560017801 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 65.4, E-value 7.9e-17 272560017802 beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431 272560017803 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 272560017804 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560017805 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 217.4, E-value 1.4e-62 272560017806 Predicted helix-turn-helix motif with score 1014.000, SD 2.64 at aa 58-79, sequence QTLTEVASATGLTRAGARRILL 272560017807 beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050 272560017808 Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751 272560017809 dimer interface [polypeptide binding]; other site 272560017810 active site 272560017811 Pfam match to entry PF00108 thiolase, Thiolase, N-terminal domain , score 332.6, E-value 2.9e-97 272560017812 PS00098 Thiolases acyl-enzyme intermediate signature. 272560017813 Pfam match to entry PF02803 thiolase_C, Thiolase, C-terminal domain , score 207.0, E-value 1.9e-59 272560017814 PS00737 Thiolases signature 2. 272560017815 PS00099 Thiolases active site. 272560017816 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560017817 PAS domain; Region: PAS_9; pfam13426 272560017818 putative active site [active] 272560017819 heme pocket [chemical binding]; other site 272560017820 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560017821 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560017822 dimer interface [polypeptide binding]; other site 272560017823 putative CheW interface [polypeptide binding]; other site 272560017824 Pfam match to entry PF00785 PAC, PAC motif , score 22.3, E-value 7.8e-06 272560017825 1 probable transmembrane helix predicted for BPSS0276 by TMHMM2.0 at aa 171-193 272560017826 Pfam match to entry PF00672 HAMP, HAMP domain , score 21.6, E-value 0.0012 272560017827 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 341.4, E-value 6.6e-100 272560017828 O-methyltransferase; Region: Methyltransf_2; pfam00891 272560017829 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560017830 S-adenosylmethionine binding site [chemical binding]; other site 272560017831 Pfam match to entry PF00891 Methyltransf_2, O-methyltransferase , score 50.1, E-value 8.8e-13 272560017832 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560017833 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 272560017834 hydrophobic ligand binding site; other site 272560017835 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560017836 iron-sulfur cluster [ion binding]; other site 272560017837 [2Fe-2S] cluster binding site [ion binding]; other site 272560017838 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 54.3, E-value 1.8e-13 272560017839 Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103 272560017840 tetramerization interface [polypeptide binding]; other site 272560017841 NAD(P) binding site [chemical binding]; other site 272560017842 catalytic residues [active] 272560017843 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 719.4, E-value 1.1e-213 272560017844 PS00070 Aldehyde dehydrogenases cysteine active site. 272560017845 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560017846 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560017847 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560017848 inhibitor-cofactor binding pocket; inhibition site 272560017849 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560017850 catalytic residue [active] 272560017851 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 550.8, E-value 6.1e-163 272560017852 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560017853 PS00636 Nt-dnaJ domain signature. 272560017854 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560017855 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560017856 DNA-binding site [nucleotide binding]; DNA binding site 272560017857 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560017858 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560017859 homodimer interface [polypeptide binding]; other site 272560017860 catalytic residue [active] 272560017861 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 48.9, E-value 7.2e-12 272560017862 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 14.5, E-value 1.9e-07 272560017863 Predicted membrane protein [Function unknown]; Region: COG1288 272560017864 10 probable transmembrane helices predicted for BPSS0283 by TMHMM2.0 at aa 40-57, 107-129, 162-184, 196-218, 238-260, 309-331, 346-364, 385-407, 435-457 and 470-492 272560017865 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560017866 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560017867 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560017868 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 123.2, E-value 3.1e-34 272560017869 PS00107 Protein kinases ATP-binding region signature. 272560017870 Predicted helix-turn-helix motif with score 1495.000, SD 4.28 at aa 24-45, sequence LGVTELASKLGINKSRTYRMLC 272560017871 N-formylglutamate amidohydrolase; Region: FGase; pfam05013 272560017872 Gene remnant. N-terminus is similar to the N-terminal region of Burkholderia pseudomallei outer membrane porin precursor Omp38 SWALL:Q7WZL2 (EMBL:AY312416) (374 aa) fasta scores: E(): 6.6e-05, 36.28% id in 113 aa. C-terminus is similar to the C-terminal region of Burkholderia pseudomallei outer membrane porin precursor Omp38 SWALL:Q7WZL2 (EMBL:AY312416) (374 aa) fasta scores: E(): 0.00059, 51.85% id in 54 aa. CDS contains frameshift and nonsense mutations and a deletion relative to the B. pseudomallei protein; outer membrane porin precursor (fragment) 272560017873 Signal peptide predicted for BPSS0286 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.435 between residues 25 and 26; signal peptide 272560017874 phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340 272560017875 EamA-like transporter family; Region: EamA; cl17759 272560017876 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 38.5, E-value 1e-08 272560017877 9 probable transmembrane helices predicted for BPSS0286 by TMHMM2.0 at aa 5-23, 30-52, 57-76, 89-108, 113-132, 139-158, 173-192, 204-226 and 231-253 272560017878 selenophosphate synthetase; Provisional; Region: PRK00943 272560017879 Selenophosphate synthetase (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195 272560017880 dimerization interface [polypeptide binding]; other site 272560017881 putative ATP binding site [chemical binding]; other site 272560017882 Pfam match to entry PF00586 AIRS, AIR synthase related protein, N-terminal domain , score 60.2, E-value 2.9e-15 272560017883 Pfam match to entry PF02769 AIRS_C, AIR synthase related protein, C-terminal domain , score 65.9, E-value 5.7e-17 272560017884 Signal peptide predicted for BPSS0288 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.945 between residues 24 and 25; signal peptide 272560017885 Purine nucleoside permease (NUP); Region: NUP; pfam06516 272560017886 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017887 Signal peptide predicted for BPSS0289 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 22 and 23; signal peptide 272560017888 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560017889 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560017890 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560017891 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 272560017892 putative effector binding pocket; other site 272560017893 putative dimerization interface [polypeptide binding]; other site 272560017894 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 160.6, E-value 1.7e-45 272560017895 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 69.9, E-value 3.4e-18 272560017896 PS00044 Bacterial regulatory proteins, lysR family signature. 272560017897 Predicted helix-turn-helix motif with score 1172.000, SD 3.18 at aa 17-38, sequence NSFTKAAETLGLPRASVTTIIQ 272560017898 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560017899 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560017900 Pfam match to entry PF00135 COesterase, Carboxylesterase , score 10.4, E-value 0.0018 272560017901 Signal peptide predicted for BPSS0292 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.518 between residues 34 and 35; signal peptide 272560017902 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 272560017903 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560017904 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560017905 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 173.1, E-value 3e-49 272560017906 AcrB/AcrD/AcrF family; Region: ACR_tran; pfam00873 272560017907 MMPL family; Region: MMPL; cl14618 272560017908 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1584.5, E-value 0 272560017909 12 probable transmembrane helices predicted for BPSS0293 by TMHMM2.0 at aa 12-34, 343-362, 369-391, 396-418, 439-461, 476-498, 550-572, 881-900, 907-929, 934-956, 982-1004 and 1014-1036 272560017910 Signal peptide predicted for BPSS0294 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.725 between residues 31 and 32; signal peptide 272560017911 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560017912 Outer membrane efflux protein; Region: OEP; pfam02321 272560017913 Outer membrane efflux protein; Region: OEP; pfam02321 272560017914 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560017915 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 163.3, E-value 2.7e-46 272560017916 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 182.3, E-value 5.1e-52 272560017917 Sodium:dicarboxylate symporter family; Region: SDF; pfam00375 272560017918 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 209.7, E-value 2.9e-60 272560017919 8 probable transmembrane helices predicted for BPSS0295 by TMHMM2.0 at aa 9-31, 41-63, 76-98, 137-159, 187-204, 219-241, 317-335 and 345-367 272560017920 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560017921 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560017922 DNA-binding site [nucleotide binding]; DNA binding site 272560017923 FCD domain; Region: FCD; pfam07729 272560017924 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 38.4, E-value 1.7e-11 272560017925 Predicted helix-turn-helix motif with score 1246.000, SD 3.43 at aa 7-28, sequence ISHRGLAHELGVGQMPVRSALQ 272560017926 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560017927 Coenzyme A binding pocket [chemical binding]; other site 272560017928 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 56.3, E-value 4.2e-14 272560017929 Membrane transport protein; Region: Mem_trans; cl09117 272560017930 8 probable transmembrane helices predicted for BPSS0298 by TMHMM2.0 at aa 4-18, 23-45, 60-82, 102-124, 184-206, 218-240, 244-266 and 273-295 272560017931 Pfam match to entry PF03547 Auxin_eff, Auxin Efflux Carrier , score 24.6, E-value 3.1e-06 272560017932 acyl-CoA synthetase; Validated; Region: PRK05850 272560017933 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560017934 acyl-activating enzyme (AAE) consensus motif; other site 272560017935 active site 272560017936 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 226.4, E-value 2.8e-65 272560017937 PS00455 AMP-binding domain signature. 272560017938 Acyl transferase domain; Region: Acyl_transf_1; cl08282 272560017939 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 69.3, E-value 5.4e-18 272560017940 3 probable transmembrane helices predicted for BPSS0301 by TMHMM2.0 at aa 34-56, 60-82 and 106-125 272560017941 Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236 272560017942 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318 272560017943 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560017944 acyl-activating enzyme (AAE) consensus motif; other site 272560017945 AMP binding site [chemical binding]; other site 272560017946 active site 272560017947 CoA binding site [chemical binding]; other site 272560017948 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 415.1, E-value 4.1e-122 272560017949 PS00455 AMP-binding domain signature. 272560017950 Diaminopimelate decarboxylase [Amino acid transport and metabolism]; Region: LysA; COG0019 272560017951 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261 272560017952 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560017953 catalytic residue [active] 272560017954 Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain , score 48.8, E-value 8e-12 272560017955 Pfam match to entry PF02784 Orn_Arg_deC_N, Pyridoxal-dependent decarboxylase, pyridoxal binding domain , score 63.3, E-value 3.4e-16 272560017956 FkbH-like domain; Region: FkbH; TIGR01686 272560017957 Ketol-acid reductoisomerase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvC; COG0059 272560017958 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991 272560017959 Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450 272560017960 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560017961 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560017962 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560017963 active site 272560017964 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560017965 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 272560017966 short chain dehydrogenase; Region: adh_short; pfam00106 272560017967 putative NADP binding site [chemical binding]; other site 272560017968 active site 272560017969 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560017970 S-adenosylmethionine binding site [chemical binding]; other site 272560017971 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560017972 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560017973 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560017974 active site 272560017975 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560017976 Condensation domain; Region: Condensation; cl19241 272560017977 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560017978 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560017979 extended (e) SDRs, subgroup 1; Region: SDR_e1; cd05235 272560017980 Male sterility protein; Region: NAD_binding_4; pfam07993 272560017981 putative NAD(P) binding site [chemical binding]; other site 272560017982 active site 272560017983 putative substrate binding site [chemical binding]; other site 272560017984 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 66.4, E-value 3.9e-17 272560017985 PS00012 Phosphopantetheine attachment site. 272560017986 Pfam match to entry PF00668 Condensation, Condensation domain , score 157.6, E-value 1.4e-44 272560017987 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 31.4, E-value 1.3e-06 272560017988 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 276.3, E-value 2.5e-80 272560017989 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 365.5, E-value 3.6e-107 272560017990 PS00606 Beta-ketoacyl synthases active site. 272560017991 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 54.0, E-value 2.1e-13 272560017992 PS00012 Phosphopantetheine attachment site. 272560017993 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 274.2, E-value 1.1e-79 272560017994 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 363.9, E-value 1.1e-106 272560017995 PS00606 Beta-ketoacyl synthases active site. 272560017996 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 32.2, E-value 7.8e-07 272560017997 Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092 272560017998 tetrameric interface [polypeptide binding]; other site 272560017999 NAD binding site [chemical binding]; other site 272560018000 catalytic residues [active] 272560018001 substrate binding site [chemical binding]; other site 272560018002 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 569.6, E-value 1.4e-168 272560018003 PS00070 Aldehyde dehydrogenases cysteine active site. 272560018004 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560018005 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018006 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560018007 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560018008 inhibitor-cofactor binding pocket; inhibition site 272560018009 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018010 catalytic residue [active] 272560018011 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 325.3, E-value 4.5e-95 272560018012 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560018013 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560018014 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317 272560018015 Cysteine-rich motif following a subset of SET domains; Region: PostSET; smart00508 272560018016 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560018017 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560018018 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560018019 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560018020 acyl-activating enzyme (AAE) consensus motif; other site 272560018021 AMP binding site [chemical binding]; other site 272560018022 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560018023 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560018024 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560018025 active site 272560018026 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 272560018027 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560018028 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560018029 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560018030 short chain dehydrogenase; Region: adh_short; pfam00106 272560018031 NAD(P) binding site [chemical binding]; other site 272560018032 active site 272560018033 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560018034 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 15.4, E-value 0.00082 272560018035 PS00012 Phosphopantetheine attachment site. 272560018036 PS00136 Serine proteases, subtilase, aspartic acid active site. 272560018037 PS00217 Sugar transport proteins signature 2. 272560018038 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 19.3, E-value 3e-05 272560018039 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 148.2, E-value 9.7e-42 272560018040 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 233.6, E-value 1.9e-67 272560018041 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 230.3, E-value 1.8e-66 272560018042 PS00606 Beta-ketoacyl synthases active site. 272560018043 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 64.3, E-value 1.6e-16 272560018044 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560018045 PS00012 Phosphopantetheine attachment site. 272560018046 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 299.2, E-value 3.2e-87 272560018047 PS00455 AMP-binding domain signature. 272560018048 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 143.8, E-value 1.9e-40 272560018049 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560018050 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560018051 DNA binding residues [nucleotide binding] 272560018052 dimerization interface [polypeptide binding]; other site 272560018053 Pfam match to entry PF03472 Autoind_bind, Autoinducer binding domain , score 109.4, E-value 4.4e-30 272560018054 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 67.6, E-value 1.7e-17 272560018055 PS00622 Bacterial regulatory proteins, luxR family signature. 272560018056 Predicted helix-turn-helix motif with score 1440.000, SD 4.09 at aa 189-210, sequence KTAWEISKILGISERTVVFHLS 272560018057 Signal peptide predicted for BPSS0313 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.954 between residues 37 and 38; signal peptide 272560018058 NLPA lipoprotein; Region: Lipoprotein_9; cl19159 272560018059 Pfam match to entry PF03180 Lipoprotein_9, NLPA lipoprotein , score 323.3, E-value 1.8e-94 272560018060 FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family; Region: FMN_nitrolo; TIGR03860 272560018061 ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258 272560018062 DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153 272560018063 Walker A/P-loop; other site 272560018064 ATP binding site [chemical binding]; other site 272560018065 Q-loop/lid; other site 272560018066 ABC transporter signature motif; other site 272560018067 Walker B; other site 272560018068 D-loop; other site 272560018069 H-loop/switch region; other site 272560018070 NIL domain; Region: NIL; pfam09383 272560018071 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 232.0, E-value 5.5e-67 272560018072 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018073 PS00211 ABC transporters family signature. 272560018074 ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Region: ectoine_ehuD; TIGR03003 272560018075 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560018076 dimer interface [polypeptide binding]; other site 272560018077 conserved gate region; other site 272560018078 putative PBP binding loops; other site 272560018079 ABC-ATPase subunit interface; other site 272560018080 5 probable transmembrane helices predicted for BPSS0316 by TMHMM2.0 at aa 20-42, 54-76, 81-103, 145-167 and 187-206 272560018081 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 60.1, E-value 3.2e-15 272560018082 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018083 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 272560018084 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560018085 active site 272560018086 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score -9.5, E-value 8.3e-05 272560018087 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560018088 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560018089 DNA-binding site [nucleotide binding]; DNA binding site 272560018090 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 272560018091 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 85.5, E-value 6.9e-23 272560018092 PS00043 Bacterial regulatory proteins, gntR family signature. 272560018093 Predicted helix-turn-helix motif with score 1149.000, SD 3.10 at aa 129-150, sequence PTERELAAQLNVSRPSLREALV 272560018094 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 272560018095 Cysteine-rich domain; Region: CCG; pfam02754 272560018096 Cysteine-rich domain; Region: CCG; pfam02754 272560018097 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 52.4, E-value 6.6e-13 272560018098 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 37.3, E-value 2.4e-08 272560018099 Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139 272560018100 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589 272560018101 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560018102 Domain of unknown function (DUF3390); Region: DUF3390; pfam11870 272560018103 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 19.2, E-value 0.00017 272560018104 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560018105 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 9.0, E-value 0.0067 272560018106 Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674 272560018107 Pfam match to entry PF02589 DUF162, Uncharacterized ACR, YkgG family COG1556 , score 47.1, E-value 2.6e-11 272560018108 L-lactate permease; Region: Lactate_perm; cl00701 272560018109 15 probable transmembrane helices predicted for BPSS0324 by TMHMM2.0 at aa 13-35, 40-62, 69-91, 128-150, 157-179, 194-213, 220-242, 252-269, 282-304, 319-336, 343-361, 388-410, 430-452, 456-478 and 549-571 272560018110 Pfam match to entry PF02652 Lactate_perm, L-lactate permease , score 964.7, E-value 1.5e-287 272560018111 Predicted membrane protein [Function unknown]; Region: COG2259 272560018112 4 probable transmembrane helices predicted for BPSS0325 by TMHMM2.0 at aa 7-26, 46-68, 75-97 and 112-131 272560018113 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560018114 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560018115 putative substrate translocation pore; other site 272560018116 12 probable transmembrane helices predicted for BPSS0326 by TMHMM2.0 at aa 21-43, 53-75, 88-110, 146-168, 175-194, 282-304, 324-346, 361-383, 390-407, 417-439, 460-477 and 487-509 272560018117 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 18.8, E-value 7.4e-06 272560018118 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560018119 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560018120 putative substrate translocation pore; other site 272560018121 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 54.9, E-value 1.1e-13 272560018122 12 probable transmembrane helices predicted for BPSS0327 by TMHMM2.0 at aa 25-47, 67-89, 102-124, 129-151, 160-182, 197-216, 251-273, 288-310, 317-339, 344-366, 379-401 and 406-425 272560018123 Malate/L-lactate dehydrogenases [Energy production and conversion]; Region: COG2055 272560018124 Pfam match to entry PF02615 ldh_2, Malate/L-lactate dehydrogenase , score 148.4, E-value 8.4e-42 272560018125 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 272560018126 dimer interface [polypeptide binding]; other site 272560018127 NADP binding site [chemical binding]; other site 272560018128 catalytic residues [active] 272560018129 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score -129.3, E-value 5.9e-10 272560018130 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 272560018131 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560018132 14 probable transmembrane helices predicted for BPSS0330 by TMHMM2.0 at aa 30-52, 62-84, 105-127, 149-171, 178-200, 220-242, 255-277, 300-322, 356-378, 383-405, 418-440, 444-461, 482-504 and 508-525 272560018133 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -147.8, E-value 1.3e-06 272560018134 Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408 272560018135 inhibitor site; inhibition site 272560018136 active site 272560018137 dimer interface [polypeptide binding]; other site 272560018138 catalytic residue [active] 272560018139 Pfam match to entry PF00701 DHDPS, Dihydrodipicolinate synthetase , score 172.3, E-value 5.2e-49 272560018140 hydroxyproline-2-epimerase; Provisional; Region: PRK13970 272560018141 Proline racemase; Region: Pro_racemase; pfam05544 272560018142 FAD dependent oxidoreductase; Region: DAO; pfam01266 272560018143 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560018144 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -27.4, E-value 1.8e-06 272560018145 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 272560018146 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 12.8, E-value 0.0018 272560018147 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 272560018148 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 69.7, E-value 4.1e-18 272560018149 PAS fold; Region: PAS_4; pfam08448 272560018150 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560018151 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018152 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018153 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 30.9, E-value 1.9e-06 272560018154 Predicted helix-turn-helix motif with score 1559.000, SD 4.50 at aa 200-221, sequence LNLKHLAGMAGMSVAQLERYFH 272560018155 PS00041 Bacterial regulatory proteins, araC family signature. 272560018156 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 46.7, E-value 3.4e-11 272560018157 Transposase; Region: DEDD_Tnp_IS110; pfam01548 272560018158 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 272560018159 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 272560018160 Pfam match to entry PF02371 Transposase_20, Transposase IS116/IS110/IS902 family , score 118.4, E-value 8.9e-33 272560018161 Pfam match to entry PF01548 Transposase_9, Transposase , score 108.4, E-value 8.9e-30 272560018162 Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082 272560018163 Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261 272560018164 4-hydroxyphenylpyruvate dioxygenase; Region: 4HPPD; TIGR01263 272560018165 N-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HPPD) and hydroxymandelate Synthase (HmaS); Region: HPPD_N_like; cd08342 272560018166 dimer interface [polypeptide binding]; other site 272560018167 C-terminal domain of 4-hydroxyphenylpyruvate dioxygenase (HppD) and hydroxymandelate Synthase (HmaS); Region: HPPD_C_like; cd07250 272560018168 active site 272560018169 Fe binding site [ion binding]; other site 272560018170 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 17.5, E-value 6.8e-05 272560018171 PS00063 Aldo/keto reductase active site signature. 272560018172 Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466 272560018173 trimer interface [polypeptide binding]; other site 272560018174 active site 272560018175 dimer interface [polypeptide binding]; other site 272560018176 Pfam match to entry PF01220 DHquinase_II, Dehydroquinase class II , score 276.9, E-value 1.7e-80 272560018177 PS01029 Dehydroquinase class II signature. 272560018178 shikimate 5-dehydrogenase; Reviewed; Region: PRK12549 272560018179 Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501 272560018180 NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065 272560018181 shikimate binding site; other site 272560018182 NAD(P) binding site [chemical binding]; other site 272560018183 Pfam match to entry PF01488 Shikimate_DH, Shikimate / quinate 5-dehydrogenase , score 158.7, E-value 6.7e-45 272560018184 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560018185 D-galactonate transporter; Region: 2A0114; TIGR00893 272560018186 putative substrate translocation pore; other site 272560018187 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -85.0, E-value 7.6e-05 272560018188 11 probable transmembrane helices predicted for BPSS0342 by TMHMM2.0 at aa 34-56, 63-85, 100-122, 162-184, 189-208, 257-279, 294-316, 328-350, 356-378, 391-413 and 418-440 272560018189 2-aminoethylphosphonate--pyruvate transaminase; Provisional; Region: PRK13479 272560018190 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560018191 catalytic residue [active] 272560018192 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score -37.2, E-value 1.6e-06 272560018193 2-aminoethylphosphonate ABC transporter, periplasmic 2-aminoethylphosphonate binding protein; Region: PhnS; TIGR03227 272560018194 2-aminoethylphosphonate ABC transporter substrate-binding protein; Provisional; Region: PRK15046 272560018195 Signal peptide predicted for BPSS0344 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.491 between residues 32 and 33; signal peptide 272560018196 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 34.3, E-value 1.8e-07 272560018197 2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT; Region: PhnT; TIGR03258 272560018198 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560018199 Walker A/P-loop; other site 272560018200 ATP binding site [chemical binding]; other site 272560018201 Q-loop/lid; other site 272560018202 ABC transporter signature motif; other site 272560018203 Walker B; other site 272560018204 D-loop; other site 272560018205 H-loop/switch region; other site 272560018206 TOBE domain; Region: TOBE_2; pfam08402 272560018207 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 213.9, E-value 1.6e-61 272560018208 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018209 PS00211 ABC transporters family signature. 272560018210 2-aminoethylphosphonate transport system permease PhnU; Provisional; Region: PRK15050 272560018211 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560018212 dimer interface [polypeptide binding]; other site 272560018213 conserved gate region; other site 272560018214 putative PBP binding loops; other site 272560018215 ABC-ATPase subunit interface; other site 272560018216 6 probable transmembrane helices predicted for BPSS0346 by TMHMM2.0 at aa 45-67, 98-120, 133-155, 175-194, 235-257 and 277-299 272560018217 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 47.7, E-value 1.7e-11 272560018218 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018219 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560018220 dimer interface [polypeptide binding]; other site 272560018221 conserved gate region; other site 272560018222 putative PBP binding loops; other site 272560018223 ABC-ATPase subunit interface; other site 272560018224 6 probable transmembrane helices predicted for BPSS0347 by TMHMM2.0 at aa 30-52, 89-111, 124-146, 156-178, 216-238 and 253-275 272560018225 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 21.2, E-value 0.0005 272560018226 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018227 Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524 272560018228 phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335 272560018229 Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146 272560018230 NAD(P) binding site [chemical binding]; other site 272560018231 catalytic residues [active] 272560018232 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 361.8, E-value 4.8e-106 272560018233 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018234 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560018235 PS00070 Aldehyde dehydrogenases cysteine active site. 272560018236 phosphonate degradation operons associated HDIG domain protein; Region: Phn-HD; TIGR03276 272560018237 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560018238 Zn2+ binding site [ion binding]; other site 272560018239 Mg2+ binding site [ion binding]; other site 272560018240 Cu(I)-responsive transcriptional regulator; Region: CueR; TIGR02044 272560018241 Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108 272560018242 DNA binding residues [nucleotide binding] 272560018243 dimer interface [polypeptide binding]; other site 272560018244 copper binding site [ion binding]; other site 272560018245 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 11-32, sequence VNIGEAAKVSGVSAKMIRYYES 272560018246 Pfam match to entry PF00376 merR, Bacterial regulatory proteins, merR family , score 57.7, E-value 1.7e-14 272560018247 PS00552 Bacterial regulatory proteins, merR family signature. 272560018248 Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961 272560018249 voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293 272560018250 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 272560018251 active site 272560018252 catalytic tetrad [active] 272560018253 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase , score 247.6, E-value 1.2e-71 272560018254 3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK13394 272560018255 classical (c) SDRs; Region: SDR_c; cd05233 272560018256 NAD(P) binding site [chemical binding]; other site 272560018257 active site 272560018258 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 236.2, E-value 3.1e-68 272560018259 PS00061 Short-chain dehydrogenases/reductases family signature. 272560018260 Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155 272560018261 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560018262 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018263 homodimer interface [polypeptide binding]; other site 272560018264 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 336.2, E-value 2.4e-98 272560018265 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560018266 excinuclease ABC subunit B; Provisional; Region: PRK05298 272560018267 Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286 272560018268 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560018269 ATP-binding site [chemical binding]; other site 272560018270 ATP binding site [chemical binding]; other site 272560018271 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560018272 nucleotide binding region [chemical binding]; other site 272560018273 ATP-binding site [chemical binding]; other site 272560018274 Ultra-violet resistance protein B; Region: UvrB; pfam12344 272560018275 UvrB/uvrC motif; Region: UVR; pfam02151 272560018276 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018277 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 70.1, E-value 3.1e-18 272560018278 Pfam match to entry PF02151 UVR, UvrB/uvrC motif , score 45.6, E-value 7.4e-11 272560018279 Signal peptide predicted for BPSS0357 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 34 and 35; signal peptide 272560018280 Fe2+ transport protein; Region: Iron_transport; pfam10634 272560018281 Signal peptide predicted for BPSS0358 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 21 and 22; signal peptide 272560018282 Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473 272560018283 PS00430 TonB-dependent receptor proteins signature 1. 272560018284 Iron permease FTR1 family; Region: FTR1; cl00475 272560018285 Pfam match to entry PF03239 FTR1, Iron permease FTR1 family , score 50.8, E-value 2e-12 272560018286 7 probable transmembrane helices predicted for BPSS0359 by TMHMM2.0 at aa 4-26, 39-61, 71-93, 114-136, 151-173, 186-203 and 248-265 272560018287 Polyferredoxin [Energy production and conversion]; Region: NapH; COG0348 272560018288 4Fe-4S binding domain; Region: Fer4_5; pfam12801 272560018289 9 probable transmembrane helices predicted for BPSS0360 by TMHMM2.0 at aa 25-47, 62-84, 117-139, 143-162, 270-292, 337-359, 372-394, 409-431 and 443-465 272560018290 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol [General function prediction only]; Region: GlcG; COG3193 272560018291 Pfam match to entry PF03928 DUF336, Domain of unknown function (DUF336) , score 160.7, E-value 1.7e-45 272560018292 Hemin uptake protein hemP; Region: hemP; pfam10636 272560018293 DUF1857, an uncharacterized ligand-binding domain of the SRPBCC domain superfamily; Region: SRPBCC_DUF1857; cd08863 272560018294 putative hydrophobic ligand binding site [chemical binding]; other site 272560018295 Pirin-related protein [General function prediction only]; Region: COG1741 272560018296 Pirin; Region: Pirin; pfam02678 272560018297 Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726 272560018298 Pfam match to entry PF02678 DUF209, Uncharacterized BCR, YhhW family COG1741 , score -43.9, E-value 3.3e-08 272560018299 LysR family transcriptional regulator; Provisional; Region: PRK14997 272560018300 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560018301 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_4; cd08473 272560018302 putative effector binding pocket; other site 272560018303 putative dimerization interface [polypeptide binding]; other site 272560018304 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 72.4, E-value 6.2e-19 272560018305 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 28-49, sequence GGFSAAERVLGISKSRLSRRLT 272560018306 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 163.8, E-value 1.9e-46 272560018307 Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848 272560018308 Pfam match to entry PF02472 ExbD, Biopolymer transport protein ExbD/TolR , score 84.2, E-value 1.7e-22 272560018309 1 probable transmembrane helix predicted for BPSS0366 by TMHMM2.0 at aa 22-44 272560018310 Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811 272560018311 Pfam match to entry PF01618 MotA_ExbB, MotA/TolQ/ExbB proton channel family , score 146.5, E-value 3e-41 272560018312 3 probable transmembrane helices predicted for BPSS0367 by TMHMM2.0 at aa 15-37, 129-151 and 178-200 272560018313 Signal peptide predicted for BPSS0368 by SignalP 2.0 HMM (Signal peptide probability 0.828) with cleavage site probability 0.315 between residues 19 and 20; signal peptide 272560018314 Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810 272560018315 Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; pfam03544 272560018316 Pfam match to entry PF03544 TonB, Gram-negative bacterial tonB protein , score 40.4, E-value 2.6e-09 272560018317 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; cl01093 272560018318 glutamate racemase; Provisional; Region: PRK00865 272560018319 Pfam match to entry PF01177 Asp_Glu_race, Asp/Glu/Hydontoin racemase , score 208.6, E-value 6.3e-60 272560018320 PS00924 Aspartate and glutamate racemases signature 2. 272560018321 PS00923 Aspartate and glutamate racemases signature 1. 272560018322 Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907 272560018323 Ferritin-like domain; Region: Ferritin; pfam00210 272560018324 heme binding site [chemical binding]; other site 272560018325 ferroxidase pore; other site 272560018326 ferroxidase diiron center [ion binding]; other site 272560018327 Pfam match to entry PF00210 ferritin, Ferritin-like domain , score 170.0, E-value 2.6e-48 272560018328 Fumarate hydratase (Fumerase); Region: Fumerase; pfam05681 272560018329 Fumarase C-terminus; Region: Fumerase_C; pfam05683 272560018330 hypothetical protein; Provisional; Region: PRK05208 272560018331 Pfam match to entry PF03350 UPF0114, Uncharacterized protein family, UPF0114 , score 244.4, E-value 1.1e-70 272560018332 3 probable transmembrane helices predicted for BPSS0373 by TMHMM2.0 at aa 29-51, 71-93 and 150-172 272560018333 Signal peptide predicted for BPSS0374 by SignalP 2.0 HMM (Signal peptide probability 0.898) with cleavage site probability 0.420 between residues 22 and 23; signal peptide 272560018334 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560018335 EamA-like transporter family; Region: EamA; pfam00892 272560018336 EamA-like transporter family; Region: EamA; pfam00892 272560018337 10 probable transmembrane helices predicted for BPSS0374 by TMHMM2.0 at aa 5-27, 31-50, 63-85, 90-112, 119-141, 151-170, 183-205, 215-234, 243-265 and 270-289 272560018338 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 79.0, E-value 6.5e-21 272560018339 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 83.8, E-value 2.3e-22 272560018340 acetyl-CoA synthetase; Provisional; Region: PRK00174 272560018341 Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966 272560018342 active site 272560018343 CoA binding site [chemical binding]; other site 272560018344 acyl-activating enzyme (AAE) consensus motif; other site 272560018345 AMP binding site [chemical binding]; other site 272560018346 acetate binding site [chemical binding]; other site 272560018347 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 445.6, E-value 2.9e-131 272560018348 PS00455 AMP-binding domain signature. 272560018349 Domain of unknown function (DUF4212); Region: DUF4212; pfam13937 272560018350 2 probable transmembrane helices predicted for BPSS0376 by TMHMM2.0 at aa 35-57 and 72-94 272560018351 Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480 272560018352 Na binding site [ion binding]; other site 272560018353 14 probable transmembrane helices predicted for BPSS0377 by TMHMM2.0 at aa 7-24, 34-56, 77-99, 104-126, 146-168, 178-200, 213-235, 366-388, 400-422, 493-515, 536-554, 564-586, 593-615 and 630-652 272560018354 Pfam match to entry PF00474 SSF, Sodium:solute symporter family , score 52.6, E-value 5.5e-13 272560018355 PS00457 Sodium:solute symporter family signature 2. 272560018356 Genomic island GI 13 272560018357 integrase; Provisional; Region: PRK09692 272560018358 Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801 272560018359 active site 272560018360 Int/Topo IB signature motif; other site 272560018361 Region with similarity of part of (BPSL0081 to BPSL0086) Genomic island GI 1 272560018362 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 27.3, E-value 1.5e-06 272560018363 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560018364 non-specific DNA binding site [nucleotide binding]; other site 272560018365 salt bridge; other site 272560018366 sequence-specific DNA binding site [nucleotide binding]; other site 272560018367 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 41.3, E-value 1.5e-09 272560018368 Predicted helix-turn-helix motif with score 1113.000, SD 2.98 at aa 30-51, sequence MSQEALADFAEIDRSHMGKIER 272560018369 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560018370 non-specific DNA binding site [nucleotide binding]; other site 272560018371 salt bridge; other site 272560018372 sequence-specific DNA binding site [nucleotide binding]; other site 272560018373 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 45.8, E-value 6.3e-11 272560018374 Predicted helix-turn-helix motif with score 1158.000, SD 3.13 at aa 30-51, sequence MSQEVLADFVEIDRSHLGKIER 272560018375 Primase C terminal 2 (PriCT-2); Region: PriCT_2; pfam08707 272560018376 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4643 272560018377 Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718 272560018378 Domain of unknown function (DUF927); Region: DUF927; pfam06048 272560018379 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018380 Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523 272560018381 Predicted helix-turn-helix motif with score 1189.000, SD 3.24 at aa 16-37, sequence VRMPALLERVGLSESEVRRRIK 272560018382 ATP-utilizing chromatin assembly and remodelling N-terminal; Region: WAC_Acf1_DNA_bd; pfam10537 272560018383 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170 272560018384 G1 box; other site 272560018385 GTP/Mg2+ binding site [chemical binding]; other site 272560018386 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018387 Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768 272560018388 multiple promoter invertase; Provisional; Region: mpi; PRK13413 272560018389 catalytic residues [active] 272560018390 catalytic nucleophile [active] 272560018391 Presynaptic Site I dimer interface [polypeptide binding]; other site 272560018392 Synaptic Antiparallel dimer interface [polypeptide binding]; other site 272560018393 Synaptic Flat tetramer interface [polypeptide binding]; other site 272560018394 Synaptic Site I dimer interface [polypeptide binding]; other site 272560018395 DNA binding site [nucleotide binding] 272560018396 Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569 272560018397 DNA-binding interface [nucleotide binding]; DNA binding site 272560018398 Pfam match to entry PF00239 resolvase, Resolvase, N terminal domain , score 198.5, E-value 6.8e-57 272560018399 PS00398 Site-specific recombinases signature 2. 272560018400 Pfam match to entry PF02796 HTH_7, Helix-turn-helix domain of resolvase , score 30.9, E-value 1.9e-06 272560018401 Predicted helix-turn-helix motif with score 975.000, SD 2.51 at aa 209-230, sequence ASVASLAKFYGTSRQTIMRVRD 272560018402 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 272560018403 This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990 272560018404 PAAR motif; Region: PAAR_motif; pfam05488 272560018405 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 272560018406 YcfA-like protein; Region: YcfA; cl00752 272560018407 Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681 272560018408 Pfam match to entry PF03681 UPF0150, Uncharacterised protein family (UPF0150) , score 52.0, E-value 8.4e-13 272560018409 Low G+C region, possible genomic island region 272560018410 Gene remnant. Similar to the C-terminal region of Escherichia coli ORF5 protein or l7094 SWALL:O53006 (EMBL:Y07545) (225 aa) fasta scores: E(): 1.5e-19, 51.78% id in 112 aa, and of Providencia rettgeri transposase Tnp391A SWALL:Q8RL20 (EMBL:AY090559) (225 aa) fasta scores: E(): 2.4e-19, 51.78% id in 112 aa;IS element hypothetical protein (fragment) 272560018411 Pfam match to entry PF00665 rve, Integrase core domain , score 88.5, E-value 1.7e-25 272560018412 Gene remnant. Similar to the N-terminal region of Bacteriophage phiE125 Gp70 SWALL:Q8W6N0 (EMBL:AF447491) (118 aa) fasta scores: E(): 1.5e-30, 89.87% id in 79 aa, and of bacteriophage SFV hypothetical 13.1 kDa protein ORF53 SWALL:Q8SBD7 (EMBL:U82619) (116 aa) fasta scores: E(): 4e-12, 49.33% id in 75 aa; bacteriophage-related protein (fragment) 272560018413 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018414 Domain of unknown function (DUF4415); Region: DUF4415; pfam14384 272560018415 PS00430 TonB-dependent receptor proteins signature 1. 272560018416 Protein of unknown function (DUF497); Region: DUF497; cl01108 272560018417 2 probable transmembrane helices predicted for BPSS0400 by TMHMM2.0 at aa 46-64 and 74-93 272560018418 1 probable transmembrane helix predicted for BPSS0401 by TMHMM2.0 at aa 20-42 272560018419 Signal peptide predicted for BPSS0402 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.687 between residues 19 and 20; signal peptide 272560018420 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 272560018421 Prohibitin family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_prohibitin; cd03401 272560018422 Integrase core domain; Region: rve; pfam00665 272560018423 Integrase core domain; Region: rve_3; pfam13683 272560018424 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family , score -4.4, E-value 0.0002 272560018425 Pfam match to entry PF00665 rve, Integrase core domain , score 82.7, E-value 4.8e-22 272560018426 Probable gene remnant. Similar to the C-terminal region of Coxiella burnetii transposase for insertion sequence element IS1111a SWALL:TRA1_COXBU (SWALL:Q45968) (339 aa) fasta scores: E(): 4.9e-23, 54.54% id in 132 aa, and to Edwardsiella ictaluri RmpB-like protein SWALL:Q6GUC9 (EMBL:AY641982) (358 aa) fasta scores: E(): 7.4e-29, 59.39% id in 133 aa;transposase (fragment) 272560018427 Probable gene remnant. Similar to the N-terminal regions of Ralstonia solanacearum ISRso16-transposase OrfA protein tisrso16A SWALL:Q8XSC1 (EMBL:AL646079) (88 aa) fasta scores: E(): 6.6e-08, 79.48% id in 39 aa, and to Xanthomonas campestris truncated transposase Tnp SWALL:Q8RJP9 (EMBL:U33548) (88 aa) fasta scores: E(): 9.8e-09, 75.61% id in 41 aa;transposase (fragment) 272560018428 Signal peptide predicted for BPSS0403 by SignalP 2.0 HMM (Signal peptide probability 0.890) with cleavage site probability 0.506 between residues 15 and 16; signal peptide 272560018429 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 272560018430 active site 272560018431 metal binding site [ion binding]; metal-binding site 272560018432 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 58.6, E-value 8.9e-15 272560018433 PS00125 Serine/threonine specific protein phosphatases signature. 272560018434 Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858 272560018435 Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150 272560018436 Pfam match to entry PF03150 CCP_MauG, Di-haem cytochrome c peroxidase , score 37.0, E-value 4.1e-13 272560018437 PS00190 Cytochrome c family heme-binding site signature. 272560018438 PS00190 Cytochrome c family heme-binding site signature. 272560018439 Signal peptide predicted for BPSS0405 by SignalP 2.0 HMM (Signal peptide probability 0.958) with cleavage site probability 0.937 between residues 19 and 20; signal peptide 272560018440 Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584 272560018441 Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial protein Rv2277c and similar proteins; Region: GDPD_Rv2277c_like; cd08580 272560018442 putative active site [active] 272560018443 catalytic site [active] 272560018444 putative metal binding site [ion binding]; other site 272560018445 Pfam match to entry PF03009 GDPD, Glycerophosphoryl diester phosphodiesterase , score 76.4, E-value 4e-20 272560018446 Integrase core domain; Region: rve; pfam00665 272560018447 Integrase core domain; Region: rve_3; pfam13683 272560018448 Predicted helix-turn-helix motif with score 1565.000, SD 4.52 at aa 23-44, sequence FGYRTLAHLLGFNKNTVQRIFR 272560018449 Pfam match to entry PF00665 rve, Integrase core domain , score 156.6, E-value 2.9e-44 272560018450 PS00294 Prenyl group binding site (CAAX box). 272560018451 Signal peptide predicted for BPSS0408 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.880 between residues 33 and 34; signal peptide 272560018452 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560018453 Bacterial Ig-like domain; Region: Big_5; pfam13205 272560018454 Pfam match to entry PF01476 LysM, LysM domain , score 2.6, E-value 2.9 272560018455 Pfam match to entry PF01476 LysM, LysM domain , score 2.4, E-value 0.32 272560018456 Pfam match to entry PF01476 LysM, LysM domain , score 11.2, E-value 0.042 272560018457 Pfam match to entry PF01476 LysM, LysM domain , score 27.8, E-value 1.6e-05 272560018458 Pfam match to entry PF01476 LysM, LysM domain , score 1.6, E-value 0.38 272560018459 Pfam match to entry PF01476 LysM, LysM domain , score 8.2, E-value 0.084 272560018460 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 185.7, E-value 4.8e-53 272560018461 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvB; COG0028 272560018462 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560018463 PYR/PP interface [polypeptide binding]; other site 272560018464 dimer interface [polypeptide binding]; other site 272560018465 TPP binding site [chemical binding]; other site 272560018466 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560018467 Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015 272560018468 TPP-binding site [chemical binding]; other site 272560018469 dimer interface [polypeptide binding]; other site 272560018470 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 78.0, E-value 1.2e-20 272560018471 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 158.4, E-value 7.9e-45 272560018472 Signal peptide predicted for BPSS0415 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.492 between residues 31 and 32; signal peptide 272560018473 Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251 272560018474 Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082 272560018475 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560018476 Signal peptide predicted for BPSS0416 by SignalP 2.0 HMM (Signal peptide probability 0.990) with cleavage site probability 0.817 between residues 25 and 26; signal peptide 272560018477 Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102 272560018478 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560018479 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 272560018480 polysaccharide export protein EpsE; Region: EpsE; TIGR03028 272560018481 SLBB domain; Region: SLBB; pfam10531 272560018482 Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251 272560018483 Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane]; Region: GumC; COG3206 272560018484 Chain length determinant protein; Region: Wzz; pfam02706 272560018485 Chain length determinant protein; Region: Wzz; cl19730 272560018486 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 272560018487 Pfam match to entry PF02706 wzz, Chain length determinant protein , score 40.0, E-value 3.4e-09 272560018488 2 probable transmembrane helices predicted for BPSS0418 by TMHMM2.0 at aa 12-34 and 325-347 272560018489 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208 272560018490 G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524 272560018491 substrate binding site; other site 272560018492 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 15.5, E-value 2.5e-09 272560018493 CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622 272560018494 CDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: CDP_GD_SDR_e; cd05252 272560018495 NAD binding site [chemical binding]; other site 272560018496 homotetramer interface [polypeptide binding]; other site 272560018497 homodimer interface [polypeptide binding]; other site 272560018498 substrate binding site [chemical binding]; other site 272560018499 active site 272560018500 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 4.3, E-value 1.1e-13 272560018501 lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407 272560018502 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 272560018503 inhibitor-cofactor binding pocket; inhibition site 272560018504 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018505 catalytic residue [active] 272560018506 Pfam match to entry PF01041 DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase , score 490.0, E-value 1.2e-144 272560018507 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560018508 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560018509 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616 272560018510 inhibitor-cofactor binding pocket; inhibition site 272560018511 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018512 catalytic residue [active] 272560018513 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 41.5, E-value 1.3e-09 272560018514 Pfam match to entry PF01041 DegT_DnrJ_EryC1, DegT/DnrJ/EryC1/StrS aminotransferase , score 503.3, E-value 1.2e-148 272560018515 Polysaccharide biosynthesis C-terminal domain; Region: Polysacc_synt_C; cl10513 272560018516 10 probable transmembrane helices predicted for BPSS0423 by TMHMM2.0 at aa 112-134, 149-171, 183-202, 207-229, 263-285, 295-317, 338-355, 365-387, 400-422 and 426-448 272560018517 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 272560018518 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 272560018519 active site 272560018520 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 93.9, E-value 2e-25 272560018521 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560018522 putative active site [active] 272560018523 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 31.4, E-value 1.4e-08 272560018524 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560018525 putative active site [active] 272560018526 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score -24.1, E-value 2.2e-05 272560018527 Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647 272560018528 trimer interface [polypeptide binding]; other site 272560018529 active site 272560018530 substrate binding site [chemical binding]; other site 272560018531 CoA binding site [chemical binding]; other site 272560018532 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 6.8, E-value 6.5 272560018533 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.1, E-value 0.22 272560018534 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.2, E-value 1.6 272560018535 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 3.9, E-value 15 272560018536 Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463 272560018537 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 272560018538 active site 272560018539 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 70.8, E-value 1.9e-18 272560018540 1 probable transmembrane helix predicted for BPSS0428 by TMHMM2.0 at aa 311-333 272560018541 8 probable transmembrane helices predicted for BPSS0429 by TMHMM2.0 at aa 2-24, 64-86, 106-128, 138-160, 172-194, 198-220, 277-299 and 314-336 272560018542 Pseudogene. Similar to Escherichia coli hypothetical 19.6 kDa protein SWALL:Q9L910 (EMBL:AF188737) (172 aa) fasta scores: E(): 2.6e-19, 40.36% id in 166 aa, and to Shewanella oneidensis conserved hypothetical protein so1764 SWALL:AAN54818 (EMBL:AE015620) (171 aa) fasta scores: E(): 2.4e-10, 29.69% id in 165 aa. CDS contains several frameshift mutations;conserved hypothetical protein (pseudogene) 272560018543 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560018544 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560018545 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560018546 putative effector binding pocket; other site 272560018547 dimerization interface [polypeptide binding]; other site 272560018548 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 193.5, E-value 2.2e-55 272560018549 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 76.1, E-value 4.8e-20 272560018550 PS00044 Bacterial regulatory proteins, lysR family signature. 272560018551 Predicted helix-turn-helix motif with score 1017.000, SD 2.65 at aa 42-63, sequence GSFTGAADKLLLSKQFVSRRVM 272560018552 Pirin-related protein [General function prediction only]; Region: COG1741 272560018553 Pirin; Region: Pirin; pfam02678 272560018554 Pfam match to entry PF02678 DUF209, Uncharacterized BCR, YhhW family COG1741 , score 403.1, E-value 1.8e-118 272560018555 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 272560018556 6 probable transmembrane helices predicted for BPSS0433 by TMHMM2.0 at aa 7-29, 44-66, 79-101, 111-130, 174-196 and 200-217 272560018557 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560018558 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560018559 ligand binding site [chemical binding]; other site 272560018560 flexible hinge region; other site 272560018561 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 22.0, E-value 0.00093 272560018562 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560018563 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018564 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018565 PS00041 Bacterial regulatory proteins, araC family signature. 272560018566 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 54.1, E-value 2e-13 272560018567 Predicted helix-turn-helix motif with score 1416.000, SD 4.01 at aa 221-242, sequence VPISQVASACGLSRSYFIKAFR 272560018568 PS00041 Bacterial regulatory proteins, araC family signature. 272560018569 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.3, E-value 1.1e-08 272560018570 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560018571 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018572 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018573 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 55.6, E-value 6.8e-14 272560018574 PS00041 Bacterial regulatory proteins, araC family signature. 272560018575 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.2, E-value 1.2e-08 272560018576 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560018577 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560018578 putative substrate translocation pore; other site 272560018579 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -109.7, E-value 0.00055 272560018580 10 probable transmembrane helices predicted for BPSS0437 by TMHMM2.0 at aa 21-43, 53-75, 87-109, 113-135, 142-164, 174-196, 257-279, 302-324, 346-368 and 373-395 272560018581 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560018582 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560018583 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560018584 putative effector binding pocket; other site 272560018585 dimerization interface [polypeptide binding]; other site 272560018586 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 73.4, E-value 3.1e-19 272560018587 Predicted helix-turn-helix motif with score 1147.000, SD 3.09 at aa 17-38, sequence GGFSKAARQLGTATSSVTRLMD 272560018588 PS00044 Bacterial regulatory proteins, lysR family signature. 272560018589 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 167.3, E-value 1.6e-47 272560018590 YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012 272560018591 catalytic triad [active] 272560018592 dimer interface [polypeptide binding]; other site 272560018593 conserved cis-peptide bond; other site 272560018594 Pfam match to entry PF00857 Isochorismatase, Isochorismatase , score -12.8, E-value 0.00011 272560018595 Protein of unknown function (DUF1427); Region: DUF1427; pfam07235 272560018596 2 probable transmembrane helices predicted for BPSS0440 by TMHMM2.0 at aa 13-35 and 50-69 272560018597 Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574 272560018598 YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300 272560018599 active site 272560018600 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018601 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587 272560018602 active site 272560018603 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 9.9, E-value 0.01 272560018604 Alginate export; Region: Alginate_exp; pfam13372 272560018605 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560018606 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560018607 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560018608 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 152.3, E-value 5.6e-43 272560018609 Probable gene remnant. Similar to the C-terminal region of Ralstonia solanacearum probable transcription regulator protein rsp1110 or rs02618 SWALL:Q8XQV8 (EMBL:AL646082) (315 aa) fasta scores: E(): 4.7e-25, 46.59% id in 176 aa, and of Burkholderia cepacia transcriptional regulator CeoR SWALL:Q8VL17 (EMBL:AY008288) (334 aa) fasta scores: E(): 7.6e-25, 48.53% id in 171 aa. CDS contains frameshift mutations after codons 7 and 138. Note, feature lacks a translational start codon; LysR-family transcriptional regulator (fragment) 272560018610 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 43.5, E-value 7.8e-12 272560018611 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018612 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560018613 Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702 272560018614 NAD(P) binding site [chemical binding]; other site 272560018615 active site 272560018616 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853 272560018617 Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain , score 16.5, E-value 1.3e-06 272560018618 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560018619 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560018620 DNA-binding site [nucleotide binding]; DNA binding site 272560018621 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560018622 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018623 homodimer interface [polypeptide binding]; other site 272560018624 catalytic residue [active] 272560018625 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 24.7, E-value 5.1e-08 272560018626 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 53.0, E-value 4.2e-13 272560018627 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 272560018628 Putative amidotransferase; Region: DUF4066; pfam13278 272560018629 conserved cys residue [active] 272560018630 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 15.5, E-value 6.2e-05 272560018631 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 272560018632 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191 272560018633 Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase , score 194.4, E-value 1.2e-55 272560018634 Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141 272560018635 hypothetical protein; Provisional; Region: PRK08609 272560018636 active site 272560018637 primer binding site [nucleotide binding]; other site 272560018638 NTP binding site [chemical binding]; other site 272560018639 metal binding triad [ion binding]; metal-binding site 272560018640 Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436 272560018641 active site 272560018642 Pfam match to entry PF02231 PHP_N, PHP domain N-terminal region , score 91.6, E-value 1e-24 272560018643 Pfam match to entry PF02811 PHP_C, PHP domain C-terminal region , score 29.4, E-value 5.4e-06 272560018644 Signal peptide predicted for BPSS0453 by SignalP 2.0 HMM (Signal peptide probability 0.984) with cleavage site probability 0.835 between residues 29 and 30; signal peptide 272560018645 Signal peptide predicted for BPSS0454 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.789 between residues 26 and 27; signal peptide 272560018646 Signal peptide predicted for BPSS0455 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.627 between residues 39 and 40; signal peptide 272560018647 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 272560018648 Outer membrane efflux protein; Region: OEP; pfam02321 272560018649 Outer membrane efflux protein; Region: OEP; pfam02321 272560018650 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560018651 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 30.9, E-value 1.9e-06 272560018652 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 36.9, E-value 3e-08 272560018653 Signal peptide predicted for BPSS0456 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.919 between residues 28 and 29 272560018654 Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132 272560018655 The first cupredoxin domain of bacteria two domain multicopper oxidase; Region: CuRO_1_2dMco_1; cd13860 272560018656 putative trimer interface [polypeptide binding]; other site 272560018657 trinuclear Cu binding site [ion binding]; other site 272560018658 The second cupredoxin domain of bacterial two domain multicopper oxidase McoN and similar proteins; Region: CuRO_D2_2dMcoN_like; cd04202 272560018659 trimer interface [polypeptide binding]; other site 272560018660 trinuclear Cu binding site [ion binding]; other site 272560018661 Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase , score 31.7, E-value 1.1e-06 272560018662 PS00080 Multicopper oxidases signature 2. 272560018663 Signal peptide predicted for BPSS0457 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23; signal peptide 272560018664 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560018665 Copper binding periplasmic protein CusF; Region: CusF_Ec; pfam11604 272560018666 Signal peptide predicted for BPSS0458 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.698 between residues 32 and 33; signal peptide 272560018667 CopC domain; Region: CopC; pfam04234 272560018668 PS00099 Thiolases active site. 272560018669 Copper resistance protein D; Region: CopD; cl00563 272560018670 8 probable transmembrane helices predicted for BPSS0459 by TMHMM2.0 at aa 10-32, 53-75, 97-116, 123-140, 160-182, 195-217, 232-254 and 285-307 272560018671 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560018672 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560018673 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560018674 dimerization interface [polypeptide binding]; other site 272560018675 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560018676 dimer interface [polypeptide binding]; other site 272560018677 putative CheW interface [polypeptide binding]; other site 272560018678 2 probable transmembrane helices predicted for BPSS0460 by TMHMM2.0 at aa 30-52 and 208-230 272560018679 Pfam match to entry PF00672 HAMP, HAMP domain , score 44.5, E-value 1.5e-10 272560018680 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 352.5, E-value 3e-103 272560018681 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 272560018682 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 272560018683 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -72.7, E-value 0.00041 272560018684 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560018685 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 272560018686 FAD dependent oxidoreductase; Region: DAO; pfam01266 272560018687 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -77.5, E-value 0.00073 272560018688 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560018689 Protein of unknown function (DUF3138); Region: DUF3138; pfam11336 272560018690 Signal peptide predicted for BPSS0463 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.859 between residues 20 and 21; signal peptide 272560018691 Signal peptide predicted for BPSS0464 by SignalP 2.0 HMM (Signal peptide probability 0.913) with cleavage site probability 0.588 between residues 31 and 32; signal peptide 272560018692 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560018693 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560018694 dimer interface [polypeptide binding]; other site 272560018695 conserved gate region; other site 272560018696 putative PBP binding loops; other site 272560018697 ABC-ATPase subunit interface; other site 272560018698 7 probable transmembrane helices predicted for BPSS0464 by TMHMM2.0 at aa 10-32, 66-88, 103-125, 138-160, 180-202, 209-231 and 241-263 272560018699 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 42.7, E-value 5.3e-10 272560018700 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018701 Signal peptide predicted for BPSS0465 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.484 between residues 21 and 22; signal peptide 272560018702 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560018703 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560018704 dimer interface [polypeptide binding]; other site 272560018705 conserved gate region; other site 272560018706 putative PBP binding loops; other site 272560018707 ABC-ATPase subunit interface; other site 272560018708 6 probable transmembrane helices predicted for BPSS0465 by TMHMM2.0 at aa 39-61, 114-136, 143-165, 195-217, 249-268 and 295-317 272560018709 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 62.9, E-value 4.6e-16 272560018710 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018711 putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607 272560018712 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560018713 Walker A/P-loop; other site 272560018714 ATP binding site [chemical binding]; other site 272560018715 Q-loop/lid; other site 272560018716 ABC transporter signature motif; other site 272560018717 Walker B; other site 272560018718 D-loop; other site 272560018719 H-loop/switch region; other site 272560018720 TOBE domain; Region: TOBE_2; pfam08402 272560018721 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 228.8, E-value 5e-66 272560018722 PS00211 ABC transporters family signature. 272560018723 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018724 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199 272560018725 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560018726 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 86.5, E-value 3.6e-23 272560018727 Signal peptide predicted for BPSS0467 by SignalP 2.0 HMM (Signal peptide probability 0.961) with cleavage site probability 0.948 between residues 64 and 65 272560018728 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560018729 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560018730 inhibitor-cofactor binding pocket; inhibition site 272560018731 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018732 catalytic residue [active] 272560018733 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 341.2, E-value 7.5e-100 272560018734 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560018735 Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174 272560018736 Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120 272560018737 Pfam match to entry PF00120 gln-synt, Glutamine synthetase, catalytic domain , score 367.0, E-value 1.3e-107 272560018738 Pfam match to entry PF03951 gln-synt_N, Glutamine synthetase, beta-Grasp domain , score 12.5, E-value 0.0013 272560018739 Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071 272560018740 Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745 272560018741 catalytic triad [active] 272560018742 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 272560018743 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560018744 non-specific DNA binding site [nucleotide binding]; other site 272560018745 salt bridge; other site 272560018746 sequence-specific DNA binding site [nucleotide binding]; other site 272560018747 Cupin domain; Region: Cupin_2; pfam07883 272560018748 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 53.9, E-value 2.2e-13 272560018749 Predicted helix-turn-helix motif with score 1970.000, SD 5.90 at aa 24-45, sequence LSQRELAKRAGVTNGTISLIEQ 272560018750 Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112 272560018751 NAD(P) binding site [chemical binding]; other site 272560018752 catalytic residues [active] 272560018753 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 751.7, E-value 2e-223 272560018754 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560018755 PS00070 Aldehyde dehydrogenases cysteine active site. 272560018756 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 272560018757 oligomer interface [polypeptide binding]; other site 272560018758 putative active site [active] 272560018759 Mn binding site [ion binding]; other site 272560018760 Pfam match to entry PF00491 arginase, Arginase , score 240.2, E-value 2e-69 272560018761 PS00147 Arginase signature 1. 272560018762 PS00148 Arginase signature 2. 272560018763 PS01053 Arginase signature 3. 272560018764 Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320 272560018765 oligomerisation interface [polypeptide binding]; other site 272560018766 mobile loop; other site 272560018767 roof hairpin; other site 272560018768 Pfam match to entry PF00166 cpn10, Chaperonin 10 Kd subunit , score 209.4, E-value 3.5e-60 272560018769 PS00681 Chaperonins cpn10 signature. 272560018770 chaperonin GroEL; Reviewed; Region: groEL; PRK12850 272560018771 GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344 272560018772 ring oligomerisation interface [polypeptide binding]; other site 272560018773 ATP/Mg binding site [chemical binding]; other site 272560018774 stacking interactions; other site 272560018775 hinge regions; other site 272560018776 Pfam match to entry PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin family , score 671.3, E-value 3.2e-199 272560018777 PS00296 Chaperonins cpn60 signature. 272560018778 Predicted membrane protein [Function unknown]; Region: COG4125 272560018779 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 272560018780 Bacterial Transmembrane Pair family; Region: BTP; pfam05232 272560018781 4 probable transmembrane helices predicted for BPSS0478 by TMHMM2.0 at aa 7-29, 34-56, 77-99 and 104-126 272560018782 ribonucleotide reductase-like protein; Provisional; Region: PRK06948 272560018783 Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317 272560018784 Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888 272560018785 active site 272560018786 dimer interface [polypeptide binding]; other site 272560018787 effector binding site; other site 272560018788 Pfam match to entry PF02867 ribonuc_red_lgC, Ribonucleotide reductase, barrel domain , score 56.3, E-value 1.9e-15 272560018789 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560018790 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 272560018791 acyl-activating enzyme (AAE) consensus motif; other site 272560018792 AMP binding site [chemical binding]; other site 272560018793 active site 272560018794 CoA binding site [chemical binding]; other site 272560018795 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 327.2, E-value 1.2e-95 272560018796 2 probable transmembrane helices predicted for BPSS0481 by TMHMM2.0 at aa 98-120 and 242-264 272560018797 PS00455 AMP-binding domain signature. 272560018798 Signal peptide predicted for BPSS0482 by SignalP 2.0 HMM (Signal peptide probability 0.989) with cleavage site probability 0.976 between residues 17 and 18; signal peptide 272560018799 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 272560018800 3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332 272560018801 Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938 272560018802 active site 272560018803 3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12879 272560018804 Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830 272560018805 dimer interface [polypeptide binding]; other site 272560018806 active site 272560018807 CoA binding pocket [chemical binding]; other site 272560018808 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 272560018809 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 49.2, E-value 5.8e-12 272560018810 acyl-CoA synthetase; Validated; Region: PRK05850 272560018811 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560018812 acyl-activating enzyme (AAE) consensus motif; other site 272560018813 active site 272560018814 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560018815 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; pfam02771 272560018816 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 272560018817 active site 272560018818 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560018819 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 300.4, E-value 1.5e-87 272560018820 PS00455 AMP-binding domain signature. 272560018821 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 3.7, E-value 1.1e-06 272560018822 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 116.0, E-value 4.7e-32 272560018823 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 39.2, E-value 5.9e-09 272560018824 PS00012 Phosphopantetheine attachment site. 272560018825 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560018826 MAPEG family; Region: MAPEG; cl09190 272560018827 3 probable transmembrane helices predicted for BPSS0488 by TMHMM2.0 at aa 54-71, 81-98 and 105-122 272560018828 Probable gene remnant. Similar to parts of Pseudomonas glumae transposase SWALL:Q9KVZ9 (EMBL:AB046460) (265 aa) fasta scores: E(): 1.1e-14, 53.02% id in 149 aa, and Burkholderia cepacia transposase for insertion sequence element IS402 SWALL:T402_BURCE (SWALL:P24536) (211 aa) fasta scores: E(): 1.4e-14, 55.7% id in 149 aa; transposase (fragment) 272560018829 Signal peptide predicted for BPSS0489 by SignalP 2.0 HMM (Signal peptide probability 0.940) with cleavage site probability 0.854 between residues 28 and 29; signal peptide 272560018830 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_2; cd08895 272560018831 putative hydrophobic ligand binding site [chemical binding]; other site 272560018832 Probable gene remnant. Similar to an internal region of Arthrobacter aurescens transposase B SWALL:AAS20166 (EMBL:AY456696) (279 aa) fasta scores: E(): 2e-06, 45.45% id in 66 aa; transposase (fragment) 272560018833 Pfam match to entry PF00665 rve, Integrase core domain , score 22.7, E-value 1.5e-06 272560018834 alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317 272560018835 Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974 272560018836 catalytic residue [active] 272560018837 TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026 272560018838 catalytic residues [active] 272560018839 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560018840 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560018841 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 234.9, E-value 7.3e-68 272560018842 PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 272560018843 peroxiredoxin; Region: AhpC; TIGR03137 272560018844 Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015 272560018845 dimer interface [polypeptide binding]; other site 272560018846 decamer (pentamer of dimers) interface [polypeptide binding]; other site 272560018847 catalytic triad [active] 272560018848 peroxidatic and resolving cysteines [active] 272560018849 Pfam match to entry PF00578 AhpC-TSA, AhpC/TSA family , score 225.6, E-value 4.6e-65 272560018850 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3397 272560018851 Chitin binding domain; Region: Chitin_bind_3; pfam03067 272560018852 Pfam match to entry PF03067 Chitin_bind_3, Chitin binding domain , score 209.6, E-value 3.2e-60 272560018853 PS00190 Cytochrome c family heme-binding site signature. 272560018854 Signal peptide predicted for BPSS0495 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.964 between residues 15 and 16; signal peptide 272560018855 Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135 272560018856 putative FMN binding site [chemical binding]; other site 272560018857 Pfam match to entry PF00881 Nitroreductase, Nitroreductase , score 45.3, E-value 9e-11 272560018858 Uncharacterized conserved protein [Function unknown]; Region: COG2308 272560018859 A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168 272560018860 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 272560018861 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 272560018862 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 272560018863 Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily , score 24.9, E-value 3.1e-05 272560018864 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 272560018865 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 272560018866 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 272560018867 Putative amidoligase enzyme (DUF2126); Region: DUF2126; pfam09899 272560018868 Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily , score 72.4, E-value 6.2e-19 272560018869 A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; pfam04174 272560018870 A predicted alpha-helical domain with a conserved ER motif; Region: Alpha-E; pfam04168 272560018871 Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305 272560018872 Bacterial transglutaminase-like N-terminal region; Region: Bact_transglu_N; pfam08379 272560018873 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 272560018874 PS00678 Trp-Asp (WD) repeats signature. 272560018875 Pfam match to entry PF01841 Transglut_core, Transglutaminase-like superfamily , score 91.1, E-value 1.5e-24 272560018876 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560018877 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560018878 DNA-binding site [nucleotide binding]; DNA binding site 272560018879 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560018880 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560018881 homodimer interface [polypeptide binding]; other site 272560018882 catalytic residue [active] 272560018883 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560018884 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 48.6, E-value 9.3e-12 272560018885 Signal peptide predicted for BPSS0503 by SignalP 2.0 HMM (Signal peptide probability 0.985) with cleavage site probability 0.964 between residues 32 and 33; signal peptide 272560018886 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560018887 drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710 272560018888 putative substrate translocation pore; other site 272560018889 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -99.3, E-value 0.00024 272560018890 12 probable transmembrane helices predicted for BPSS0503 by TMHMM2.0 at aa 5-27, 42-64, 71-92, 96-118, 131-153, 158-180, 209-228, 241-263, 270-292, 305-327, 334-356 and 366-385 272560018891 PS00216 Sugar transport proteins signature 1. 272560018892 Predicted membrane protein [Function unknown]; Region: COG1289 272560018893 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 272560018894 5 probable transmembrane helices predicted for BPSS0504 by TMHMM2.0 at aa 33-55, 59-77, 84-106, 126-148 and 160-182 272560018895 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560018896 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 272560018897 conserved cys residue [active] 272560018898 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018899 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560018900 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 37.6, E-value 1.9e-08 272560018901 PS00041 Bacterial regulatory proteins, araC family signature. 272560018902 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 23.9, E-value 0.00025 272560018903 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 84.1, E-value 1.9e-22 272560018904 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 272560018905 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 272560018906 conserved cys residue [active] 272560018907 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 48.7, E-value 8.2e-12 272560018908 2 probable transmembrane helices predicted for BPSS0506 by TMHMM2.0 at aa 35-57 and 124-143 272560018909 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560018910 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560018911 catalytic residue [active] 272560018912 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score -13.9, E-value 1e-07 272560018913 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560018914 phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297 272560018915 PYR/PP interface [polypeptide binding]; other site 272560018916 dimer interface [polypeptide binding]; other site 272560018917 TPP binding site [chemical binding]; other site 272560018918 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629 272560018919 TPP-binding site [chemical binding]; other site 272560018920 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score -20.6, E-value 2.7e-05 272560018921 PS00187 Thiamine pyrophosphate enzymes signature. 272560018922 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 272560018923 tetramer interface [polypeptide binding]; other site 272560018924 active site 272560018925 Mg2+/Mn2+ binding site [ion binding]; other site 272560018926 Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523 272560018927 active site 272560018928 metal-binding site 272560018929 Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523 272560018930 active site 272560018931 metal-binding site 272560018932 putative membrane protein; Region: HpnL; TIGR03476 272560018933 5 probable transmembrane helices predicted for BPSS0511 by TMHMM2.0 at aa 7-29, 39-61, 115-137, 147-169 and 221-243 272560018934 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 272560018935 Pfam match to entry PF03171 2OG-FeII_Oxy, 2OG-Fe(II) oxygenase superfamily , score 16.3, E-value 0.0012 272560018936 CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066 272560018937 Pfam match to entry PF01066 CDP-OH_P_transf, CDP-alcohol phosphatidyltransferase , score 22.4, E-value 1.9e-05 272560018938 4 probable transmembrane helices predicted for BPSS0513 by TMHMM2.0 at aa 50-72, 104-123, 128-150 and 188-205 272560018939 PS00379 CDP-alcohol phosphatidyltransferases signature. 272560018940 Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550 272560018941 succinate CoA transferase; Region: YgfH_subfam; TIGR03458 272560018942 Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336 272560018943 Pfam match to entry PF02550 AcetylCoA_hydro, Acetyl-CoA hydrolase/transferase , score 521.0, E-value 5.8e-154 272560018944 ImpA-related N-terminal; Region: ImpA-rel_N; cl19907 272560018945 type VI secretion protein, VC_A0107 family; Region: VI_chp_5; TIGR03358 272560018946 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 272560018947 Protein of unknown function (DUF796); Region: DUF796; pfam05638 272560018948 Gene 25-like lysozyme; Region: GPW_gp25; pfam04965 272560018949 Bacterial protein of unknown function (DUF879); Region: DUF879; pfam05947 272560018950 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560018951 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 272560018952 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560018953 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560018954 Walker A motif; other site 272560018955 ATP binding site [chemical binding]; other site 272560018956 Walker B motif; other site 272560018957 arginine finger; other site 272560018958 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944 272560018959 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560018960 Walker A motif; other site 272560018961 ATP binding site [chemical binding]; other site 272560018962 Walker B motif; other site 272560018963 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560018964 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 11.9, E-value 9.8e-06 272560018965 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018966 PS00870 Chaperonins clpA/B signature 1. 272560018967 PS00017 ATP/GTP-binding site motif A (P-loop). 272560018968 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560018969 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560018970 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560018971 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560018972 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560018973 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560018974 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; cl02212 272560018975 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 272560018976 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 272560018977 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 1.7, E-value 0.3 272560018978 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 26.3, E-value 4.8e-05 272560018979 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 272560018980 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 272560018981 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560018982 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 1.0, E-value 0.35 272560018983 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 22.5, E-value 0.00065 272560018984 Protein of unknown function (DUF3540); Region: DUF3540; pfam12059 272560018985 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 272560018986 Signal peptide predicted for BPSS0529 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.630 between residues 27 and 28; signal peptide 272560018987 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 272560018988 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560018989 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 272560018990 hypothetical protein; Provisional; Region: PRK14693 272560018991 Signal peptide predicted for BPSS0531 by SignalP 2.0 HMM (Signal peptide probability 0.831) with cleavage site probability 0.320 between residues 32 and 33; signal peptide 272560018992 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560018993 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560018994 ligand binding site [chemical binding]; other site 272560018995 1 probable transmembrane helix predicted for BPSS0531 by TMHMM2.0 at aa 295-317 272560018996 Pfam match to entry PF00691 OmpA, OmpA family , score 65.8, E-value 5.8e-17 272560018997 Signal peptide predicted for BPSS0532 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.791 between residues 26 and 27; signal peptide 272560018998 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 272560018999 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560019000 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 272560019001 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560019002 3 probable transmembrane helices predicted for BPSS0532 by TMHMM2.0 at aa 9-31, 41-60 and 435-457 272560019003 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019004 Signal peptide predicted for BPSS0535 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.979 between residues 38 and 39; signal peptide 272560019005 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560019006 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 272560019007 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 272560019008 active site 272560019009 TDP-binding site; other site 272560019010 acceptor substrate-binding pocket; other site 272560019011 homodimer interface [polypeptide binding]; other site 272560019012 Pfam match to entry PF00201 UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase , score 18.3, E-value 1.6e-05 272560019013 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560019014 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560019015 putative substrate translocation pore; other site 272560019016 14 probable transmembrane helices predicted for BPSS0538 by TMHMM2.0 at aa 34-56, 71-93, 100-119, 124-146, 159-181, 186-208, 215-237, 247-269, 289-311, 326-348, 355-377, 387-409, 422-439 and 498-515 272560019017 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -118.4, E-value 0.0011 272560019018 RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526 272560019019 L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556 272560019020 Ligand binding site; other site 272560019021 Signal peptide predicted for BPSS0540 by SignalP 2.0 HMM (Signal peptide probability 0.775) with cleavage site probability 0.489 between residues 41 and 42; signal peptide 272560019022 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560019023 Outer membrane efflux protein; Region: OEP; pfam02321 272560019024 Outer membrane efflux protein; Region: OEP; pfam02321 272560019025 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560019026 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 53.9, E-value 2.4e-13 272560019027 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 118.9, E-value 6.4e-33 272560019028 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 272560019029 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560019030 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560019031 1 probable transmembrane helix predicted for BPSS0541 by TMHMM2.0 at aa 21-43 272560019032 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 195.9, E-value 4e-56 272560019033 Glycosyl hydrolases family 32; Region: Glyco_32; smart00640 272560019034 Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996 272560019035 substrate binding [chemical binding]; other site 272560019036 active site 272560019037 Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244 272560019038 Pfam match to entry PF00251 Glyco_hydro_32, Glycosyl hydrolases family 32 , score 288.3, E-value 6.3e-84 272560019039 PS00609 Glycosyl hydrolases family 32 active site. 272560019040 Glycosyl hydrolase family 68, includes levansucrase, beta-fructofuranosidase and inulosucrase; Region: GH68; cd08997 272560019041 active site 272560019042 Pfam match to entry PF02435 Glyco_hydro_68, Levansucrase/Invertase , score 646.8, E-value 7.6e-192 272560019043 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560019044 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560019045 DNA binding site [nucleotide binding] 272560019046 domain linker motif; other site 272560019047 Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271 272560019048 ligand binding site [chemical binding]; other site 272560019049 Predicted helix-turn-helix motif with score 2157.000, SD 6.53 at aa 3-24, sequence VNLKALSEALGLSRTTVSRALN 272560019050 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 94.2, E-value 1.7e-25 272560019051 formaldehyde dehydrogenase, glutathione-independent; Region: fdhA_non_GSH; TIGR02819 272560019052 Pseudomonas putida aldehyde-dismutating formaldehyde dehydrogenase (PFDH); Region: PFDH_like; cd08282 272560019053 NAD binding site [chemical binding]; other site 272560019054 catalytic Zn binding site [ion binding]; other site 272560019055 structural Zn binding site [ion binding]; other site 272560019056 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 208.4, E-value 6.9e-60 272560019057 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560019058 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560019059 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 272560019060 conserved cys residue [active] 272560019061 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019062 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 30.5, E-value 2.5e-06 272560019063 PS00041 Bacterial regulatory proteins, araC family signature. 272560019064 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 42.9, E-value 4.6e-10 272560019065 Predicted helix-turn-helix motif with score 2286.000, SD 6.97 at aa 281-302, sequence LSREELARLANMSQRQLQRLFR 272560019066 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 30.1, E-value 3.2e-06 272560019067 Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378 272560019068 dimer interface [polypeptide binding]; other site 272560019069 active site 272560019070 glycine-pyridoxal phosphate binding site [chemical binding]; other site 272560019071 folate binding site [chemical binding]; other site 272560019072 Pfam match to entry PF00464 SHMT, Serine hydroxymethyltransferase , score 845.8, E-value 9.7e-252 272560019073 PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 272560019074 Membrane dipeptidase (Peptidase family M19); Region: Peptidase_M19; pfam01244 272560019075 active site 272560019076 Pfam match to entry PF01244 Renal_dipeptase, Renal dipeptidase , score -52.8, E-value 4.8e-07 272560019077 The V4R (vinyl 4 reductase) domain is a predicted small molecular binding domain, that may bind to hydrocarbons; Region: V4R; smart00989 272560019078 mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997 272560019079 Old yellow enzyme (OYE)-related FMN binding domain, group 3. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_3_FMN; cd04734 272560019080 putative active site [active] 272560019081 putative FMN binding site [chemical binding]; other site 272560019082 putative substrate binding site [chemical binding]; other site 272560019083 putative catalytic residue [active] 272560019084 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560019085 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 272560019086 NAD(P) binding site [chemical binding]; other site 272560019087 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 228.4, E-value 6.6e-66 272560019088 Signal peptide predicted for BPSS0551 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.952 between residues 21 and 22; signal peptide 272560019089 Domain of unknown function (DUF3483); Region: DUF3483; pfam11982 272560019090 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 272560019091 4Fe-4S dicluster domain; Region: Fer4_8; pfam13183 272560019092 Cysteine-rich domain; Region: CCG; pfam02754 272560019093 Cysteine-rich domain; Region: CCG; pfam02754 272560019094 4 probable transmembrane helices predicted for BPSS0551 by TMHMM2.0 at aa 4-23, 71-93, 97-116 and 136-158 272560019095 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 15.1, E-value 0.00075 272560019096 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560019097 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560019098 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 11.3, E-value 0.0072 272560019099 Pfam match to entry PF02754 DUF224, Domain of unknown function (DUF224) , score 61.2, E-value 1.5e-15 272560019100 PS01047 Heavy-metal-associated domain. 272560019101 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 272560019102 Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025 272560019103 Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766 272560019104 Pfam match to entry PF00766 ETF_alpha, Electron transfer flavoprotein alpha subunit , score 29.9, E-value 2.6e-12 272560019105 PS00696 Electron transfer flavoprotein alpha-subunit signature. 272560019106 Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which binds to Adenosine nucleotide; Region: AANH_like; cl00292 272560019107 Ligand Binding Site [chemical binding]; other site 272560019108 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 272560019109 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 272560019110 [2Fe-2S] cluster binding site [ion binding]; other site 272560019111 C-terminal catalytic domain of GbcA (glycine betaine catabolism A) from Pseudomonas aeruginosa PAO1 and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_GbcA-like; cd08884 272560019112 putative alpha subunit interface [polypeptide binding]; other site 272560019113 putative active site [active] 272560019114 putative substrate binding site [chemical binding]; other site 272560019115 Fe binding site [ion binding]; other site 272560019116 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 96.1, E-value 4.6e-26 272560019117 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560019118 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 272560019119 Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215 272560019120 FAD binding pocket [chemical binding]; other site 272560019121 FAD binding motif [chemical binding]; other site 272560019122 phosphate binding motif [ion binding]; other site 272560019123 beta-alpha-beta structure motif; other site 272560019124 NAD binding pocket [chemical binding]; other site 272560019125 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560019126 catalytic loop [active] 272560019127 iron binding site [ion binding]; other site 272560019128 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 88.3, E-value 9.9e-24 272560019129 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 45.3, E-value 9.2e-11 272560019130 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 74.9, E-value 1.1e-19 272560019131 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560019132 ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; COG2113 272560019133 Signal peptide predicted for BPSS0556 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.965 between residues 25 and 26; signal peptide 272560019134 Amino acid permease; Region: AA_permease_2; pfam13520 272560019135 13 probable transmembrane helices predicted for BPSS0557 by TMHMM2.0 at aa 46-68, 75-97, 107-129, 136-158, 173-195, 208-227, 258-280, 301-323, 346-368, 424-446, 461-483, 490-512 and 538-560 272560019136 formyltetrahydrofolate deformylase; Reviewed; Region: PRK13011 272560019137 N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875 272560019138 Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648 272560019139 putative active site [active] 272560019140 putative substrate binding site [chemical binding]; other site 272560019141 putative cosubstrate binding site; other site 272560019142 catalytic site [active] 272560019143 Pfam match to entry PF00551 formyl_transf, Formyl transferase , score 119.2, E-value 5.2e-33 272560019144 Pfam match to entry PF01842 ACT, ACT domain , score 16.1, E-value 0.056 272560019145 putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418 272560019146 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560019147 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560019148 substrate binding pocket [chemical binding]; other site 272560019149 dimerization interface [polypeptide binding]; other site 272560019150 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 137.5, E-value 1.6e-38 272560019151 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 89.2, E-value 5.5e-24 272560019152 Predicted helix-turn-helix motif with score 1242.000, SD 3.42 at aa 36-57, sequence ASFTAAARELGSTQPAVSQRVV 272560019153 choline-sulfatase; Region: chol_sulfatase; TIGR03417 272560019154 Sulfatase; Region: Sulfatase; pfam00884 272560019155 Choline sulfatase enzyme C terminal; Region: Choline_sulf_C; pfam12411 272560019156 Pfam match to entry PF00884 Sulfatase, Sulfatase , score 151.1, E-value 1.2e-42 272560019157 ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131 272560019158 Signal peptide predicted for BPSS0562 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.732 between residues 25 and 26; signal peptide 272560019159 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560019160 trimer interface [polypeptide binding]; other site 272560019161 eyelet of channel; other site 272560019162 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -38.5, E-value 9.5e-05 272560019163 Signal peptide predicted for BPSS0563 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 22 and 23; signal peptide 272560019164 M28 Zn-Peptidase Aeromonas (Vibrio) proteolytica aminopeptidase; Region: M28_AAP; cd03879 272560019165 active site 272560019166 metal binding site [ion binding]; metal-binding site 272560019167 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 30.0, E-value 7.8e-09 272560019168 Signal peptide predicted for BPSS0564 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27; signal peptide 272560019169 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 272560019170 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 272560019171 Peptidase M36 family also known as fungalysin family; Region: M36; cd09596 272560019172 Zn binding site [ion binding]; other site 272560019173 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560019174 Pfam match to entry PF03413 Pep_M4_propep, Thermolysin metallopeptidase, propeptide , score 33.7, E-value 2.8e-07 272560019175 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560019176 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 272560019177 conserved cys residue [active] 272560019178 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019179 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 53.9, E-value 2.3e-13 272560019180 PS00041 Bacterial regulatory proteins, araC family signature. 272560019181 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 7.0, E-value 0.47 272560019182 Predicted helix-turn-helix motif with score 1501.000, SD 4.30 at aa 250-271, sequence LSSDALAREVGITRRQLERLFS 272560019183 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 7.9, E-value 0.00021 272560019184 Signal peptide predicted for BPSS0566 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 25 and 26; signal peptide 272560019185 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 272560019186 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560019187 Uncharacterized conserved protein [Function unknown]; Region: COG3246 272560019188 3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK07066 272560019189 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737 272560019190 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725 272560019191 1 probable transmembrane helix predicted for BPSS0568 by TMHMM2.0 at aa 29-51 272560019192 Pfam match to entry PF02737 3HCDH_N, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain , score 69.3, E-value 5.2e-18 272560019193 Pfam match to entry PF00725 3HCDH, 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain , score 67.5, E-value 1.8e-17 272560019194 4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586 272560019195 active site 272560019196 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560019197 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560019198 PS01173 Lipolytic enzymes G-D-X-G family, histidine active site. 272560019199 PS01174 Lipolytic enzymes G-D-X-G family, serine active site. 272560019200 Signal peptide predicted for BPSS0571 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 22 and 23; signal peptide 272560019201 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560019202 retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327 272560019203 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 272560019204 putative NAD(P) binding site [chemical binding]; other site 272560019205 active site 272560019206 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 90.0, E-value 3e-24 272560019207 Domain of unknown function (DUF3331); Region: DUF3331; pfam11811 272560019208 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 272560019209 Squalene epoxidase; Region: SE; cl17314 272560019210 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560019211 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -75.1, E-value 0.00055 272560019212 Signal peptide predicted for BPSS0575 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.979 between residues 24 and 25; signal peptide 272560019213 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560019214 dimerization interface [polypeptide binding]; other site 272560019215 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560019216 ligand binding site [chemical binding]; other site 272560019217 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 138.8, E-value 6.2e-39 272560019218 Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582 272560019219 TM-ABC transporter signature motif; other site 272560019220 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 242.0, E-value 5.4e-70 272560019221 8 probable transmembrane helices predicted for BPSS0576 by TMHMM2.0 at aa 15-37, 46-65, 69-91, 104-126, 153-175, 206-228, 243-265 and 282-299 272560019222 leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301 272560019223 Domain of unknown function (DUF3382); Region: DUF3382; pfam11862 272560019224 Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581 272560019225 TM-ABC transporter signature motif; other site 272560019226 9 probable transmembrane helices predicted for BPSS0577 by TMHMM2.0 at aa 20-38, 53-72, 93-110, 120-151, 164-186, 263-285, 313-335, 350-372 and 384-402 272560019227 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score 225.1, E-value 6.8e-65 272560019228 leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300 272560019229 ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219 272560019230 Walker A/P-loop; other site 272560019231 ATP binding site [chemical binding]; other site 272560019232 Q-loop/lid; other site 272560019233 ABC transporter signature motif; other site 272560019234 Walker B; other site 272560019235 D-loop; other site 272560019236 H-loop/switch region; other site 272560019237 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 211.3, E-value 9.7e-61 272560019238 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019239 PS00063 Aldo/keto reductase active site signature. 272560019240 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410 272560019241 ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224 272560019242 Walker A/P-loop; other site 272560019243 ATP binding site [chemical binding]; other site 272560019244 Q-loop/lid; other site 272560019245 ABC transporter signature motif; other site 272560019246 Walker B; other site 272560019247 D-loop; other site 272560019248 H-loop/switch region; other site 272560019249 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 190.7, E-value 1.5e-54 272560019250 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019251 PS00211 ABC transporters family signature. 272560019252 Signal peptide predicted for BPSS0580 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 29 and 30; signal peptide 272560019253 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 272560019254 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560019255 Bacterial SH3 domain; Region: SH3_3; pfam08239 272560019256 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 27.9, E-value 2e-06 272560019257 salicylate biosynthesis isochorismate synthase; Validated; Region: PRK07054 272560019258 chorismate binding enzyme; Region: Chorismate_bind; cl10555 272560019259 Pfam match to entry PF00425 chorismate_bind, chorismate binding enzyme , score 282.7, E-value 3.1e-82 272560019260 isochorismate-pyruvate lyase; Reviewed; Region: PRK07075 272560019261 Pfam match to entry PF01817 Chorismate_mut, Chorismate mutase , score 95.2, E-value 8.5e-26 272560019262 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560019263 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560019264 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 203.2, E-value 2.7e-58 272560019265 Peptide arylation enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntE; COG1021 272560019266 2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920 272560019267 acyl-activating enzyme (AAE) consensus motif; other site 272560019268 active site 272560019269 AMP binding site [chemical binding]; other site 272560019270 substrate binding site [chemical binding]; other site 272560019271 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 354.6, E-value 6.8e-104 272560019272 PS00455 AMP-binding domain signature. 272560019273 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560019274 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019275 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 11.7, E-value 0.14 272560019276 PS00041 Bacterial regulatory proteins, araC family signature. 272560019277 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 41.0, E-value 1.7e-09 272560019278 Phosphopantetheine attachment site; Region: PP-binding; cl09936 272560019279 Condensation domain; Region: Condensation; cl19241 272560019280 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560019281 Nonribosomal peptide synthase; Region: NRPS; pfam08415 272560019282 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560019283 acyl-activating enzyme (AAE) consensus motif; other site 272560019284 active site 272560019285 AMP binding site [chemical binding]; other site 272560019286 CoA binding site [chemical binding]; other site 272560019287 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173 272560019288 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560019289 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560019290 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 35.3, E-value 8.9e-08 272560019291 Pfam match to entry PF00668 Condensation, Condensation domain , score 122.3, E-value 5.9e-34 272560019292 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 445.1, E-value 4e-131 272560019293 PS00455 AMP-binding domain signature. 272560019294 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 66.7, E-value 3.2e-17 272560019295 PS00012 Phosphopantetheine attachment site. 272560019296 Condensation domain; Region: Condensation; cl19241 272560019297 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560019298 Nonribosomal peptide synthase; Region: NRPS; pfam08415 272560019299 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560019300 acyl-activating enzyme (AAE) consensus motif; other site 272560019301 active site 272560019302 AMP binding site [chemical binding]; other site 272560019303 CoA binding site [chemical binding]; other site 272560019304 Methyltransferase domain; Region: Methyltransf_12; pfam08242 272560019305 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560019306 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560019307 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560019308 Pfam match to entry PF00668 Condensation, Condensation domain , score 63.8, E-value 2.4e-16 272560019309 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 464.4, E-value 6.2e-137 272560019310 PS00211 ABC transporters family signature. 272560019311 PS00455 AMP-binding domain signature. 272560019312 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 28.6, E-value 1.8e-07 272560019313 PS00012 Phosphopantetheine attachment site. 272560019314 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 17.5, E-value 3.8e-05 272560019315 thiazolinyl imide reductase; Region: thiaz-red; TIGR01761 272560019316 Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; cl19130 272560019317 Signal peptide predicted for BPSS0589 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.972 between residues 26 and 27; signal peptide 272560019318 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560019319 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560019320 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 272560019321 Walker A/P-loop; other site 272560019322 ATP binding site [chemical binding]; other site 272560019323 Q-loop/lid; other site 272560019324 ABC transporter signature motif; other site 272560019325 Walker B; other site 272560019326 D-loop; other site 272560019327 H-loop/switch region; other site 272560019328 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 15.2, E-value 7.1e-05 272560019329 5 probable transmembrane helices predicted for BPSS0589 by TMHMM2.0 at aa 12-34, 54-76, 150-172, 238-260 and 265-287 272560019330 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 194.9, E-value 8.1e-56 272560019331 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019332 PS00211 ABC transporters family signature. 272560019333 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 272560019334 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560019335 Walker A/P-loop; other site 272560019336 ATP binding site [chemical binding]; other site 272560019337 Q-loop/lid; other site 272560019338 ABC transporter signature motif; other site 272560019339 Walker B; other site 272560019340 D-loop; other site 272560019341 H-loop/switch region; other site 272560019342 5 probable transmembrane helices predicted for BPSS0590 by TMHMM2.0 at aa 20-42, 52-74, 125-147, 152-169 and 236-258 272560019343 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 174.2, E-value 1.4e-49 272560019344 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019345 PS00211 ABC transporters family signature. 272560019346 Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism]; Region: FhuE; COG4773 272560019347 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560019348 N-terminal plug; other site 272560019349 ligand-binding site [chemical binding]; other site 272560019350 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 87.5, E-value 1.7e-23 272560019351 PS01156 TonB-dependent receptor proteins signature 2. 272560019352 3 probable transmembrane helices predicted for BPSS0592 by TMHMM2.0 at aa 5-27, 39-61 and 66-85 272560019353 Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182 272560019354 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 272560019355 Pfam match to entry PF03929 DUF337, Uncharacterized iron-regulated membrane protein (DUF337) , score -17.8, E-value 7.7e-09 272560019356 8 probable transmembrane helices predicted for BPSS0593 by TMHMM2.0 at aa 12-34, 130-152, 173-195, 338-360, 373-395, 405-424, 431-453 and 463-480 272560019357 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 272560019358 siderophore transporter, RhtX/FptX family; Region: sider_RhtX_FptX; TIGR02718 272560019359 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560019360 PS00228 Tubulin-beta mRNA autoregulation signal. 272560019361 10 probable transmembrane helices predicted for BPSS0594 by TMHMM2.0 at aa 7-29, 44-66, 87-109, 144-166, 173-192, 217-239, 252-274, 279-301, 313-335 and 376-398 272560019362 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560019363 catalytic loop [active] 272560019364 iron binding site [ion binding]; other site 272560019365 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 66.0, E-value 5.4e-17 272560019366 Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription]; Region: AcoR; COG3284 272560019367 GAF domain; Region: GAF; pfam01590 272560019368 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560019369 Walker A motif; other site 272560019370 ATP binding site [chemical binding]; other site 272560019371 Walker B motif; other site 272560019372 arginine finger; other site 272560019373 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560019374 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 37.4, E-value 2.1e-08 272560019375 Predicted helix-turn-helix motif with score 1811.000, SD 5.36 at aa 619-640, sequence GNVSAAARELGLARNTVYRHLR 272560019376 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 374.1, E-value 9.2e-110 272560019377 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560019378 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560019379 Protein of unknown function (DUF2964); Region: DUF2964; pfam11177 272560019380 Signal peptide predicted for BPSS0597 by SignalP 2.0 HMM (Signal peptide probability 0.951) with cleavage site probability 0.556 between residues 25 and 26; signal peptide 272560019381 2 probable transmembrane helices predicted for BPSS0597 by TMHMM2.0 at aa 7-26 and 36-58 272560019382 Protein of unknown function (DUF1488); Region: DUF1488; pfam07369 272560019383 PS00153 ATP synthase gamma subunit signature. 272560019384 1 probable transmembrane helix predicted for BPSS0600 by TMHMM2.0 at aa 20-42 272560019385 Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism]; Region: COG2252 272560019386 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560019387 10 probable transmembrane helices predicted for BPSS0601 by TMHMM2.0 at aa 20-42, 54-76, 96-118, 135-157, 172-189, 196-218, 233-255, 324-346, 380-402 and 415-432 272560019388 Pfam match to entry PF00860 xan_ur_permease, Permease , score 136.5, E-value 3.1e-38 272560019389 PS00310 Lysosome-associated membrane glycoproteins duplicated domain signature. 272560019390 TIGR02594 family protein; Region: TIGR02594 272560019391 Protein of unknown function (DUF2917); Region: DUF2917; pfam11142 272560019392 Sulfite exporter TauE/SafE; Region: TauE; pfam01925 272560019393 5 probable transmembrane helices predicted for BPSS0605 by TMHMM2.0 at aa 7-29, 44-63, 70-92, 97-116 and 128-150 272560019394 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560019395 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560019396 Signal peptide predicted for BPSS0606 by SignalP 2.0 HMM (Signal peptide probability 0.966) with cleavage site probability 0.833 between residues 20 and 21; signal peptide 272560019397 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560019398 dimerization interface [polypeptide binding]; other site 272560019399 substrate binding pocket [chemical binding]; other site 272560019400 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 81.0, E-value 1.6e-21 272560019401 Predicted helix-turn-helix motif with score 2137.000, SD 6.47 at aa 14-35, sequence GSFTAAADELCVTHSAVSRQIQ 272560019402 PS00044 Bacterial regulatory proteins, lysR family signature. 272560019403 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 125.5, E-value 6.3e-35 272560019404 Streptomyces putative phosphonoformaldehyde dehydrogenase PhpJ-like; Region: ALDH_PhpJ; cd07146 272560019405 NAD(P) binding site [chemical binding]; other site 272560019406 catalytic residues [active] 272560019407 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 316.2, E-value 2.6e-92 272560019408 PS00070 Aldehyde dehydrogenases cysteine active site. 272560019409 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560019410 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019411 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560019412 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560019413 active site 272560019414 iron coordination sites [ion binding]; other site 272560019415 substrate binding pocket [chemical binding]; other site 272560019416 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 83.0, E-value 3.9e-22 272560019417 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560019418 phosphonopyruvate decarboxylase; Region: Ppyr-DeCO2ase; TIGR03297 272560019419 PYR/PP interface [polypeptide binding]; other site 272560019420 dimer interface [polypeptide binding]; other site 272560019421 TPP binding site [chemical binding]; other site 272560019422 Thiamine pyrophosphate (TPP) family, PpyrDC subfamily, TPP-binding module; composed of proteins similar to phosphonopyruvate decarboxylase (PpyrDC) proteins. PpyrDC is a homotrimeric enzyme which functions in the biosynthesis of C-P compounds such as...; Region: TPP_PpyrDC; cd03371 272560019423 TPP-binding site; other site 272560019424 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score -4.4, E-value 2e-06 272560019425 PS00187 Thiamine pyrophosphate enzymes signature. 272560019426 Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377 272560019427 tetramer interface [polypeptide binding]; other site 272560019428 active site 272560019429 Mg2+/Mn2+ binding site [ion binding]; other site 272560019430 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560019431 1 probable transmembrane helix predicted for BPSS0611 by TMHMM2.0 at aa 205-227 272560019432 short chain dehydrogenase; Validated; Region: PRK05855 272560019433 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560019434 classical (c) SDRs; Region: SDR_c; cd05233 272560019435 NAD(P) binding site [chemical binding]; other site 272560019436 active site 272560019437 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 208.3, E-value 7.7e-60 272560019438 PS00061 Short-chain dehydrogenases/reductases family signature. 272560019439 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 55.8, E-value 6.3e-14 272560019440 A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066 272560019441 active site 272560019442 Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330 272560019443 Uncharacterized prokaryotic subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_eoslipins_u1; cd08826 272560019444 trimer interface [polypeptide binding]; other site 272560019445 Pfam match to entry PF01145 Band_7, SPFH domain / Band 7 family , score 256.4, E-value 2.6e-74 272560019446 2 probable transmembrane helices predicted for BPSS0614 by TMHMM2.0 at aa 4-26 and 33-55 272560019447 Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones]; Region: NfeD; COG1030 272560019448 Nodulation formation efficiency D (NfeD) is a membrane-bound ClpP-class protease; Region: Clp_protease_NfeD_1; cd07020 272560019449 dimer interface [polypeptide binding]; other site 272560019450 active site residues [active] 272560019451 NfeD-like C-terminal, partner-binding; Region: NfeD; pfam01957 272560019452 Pfam match to entry PF01957 DUF107, Protein of unknown function DUF107 , score 482.2, E-value 2.6e-142 272560019453 6 probable transmembrane helices predicted for BPSS0615 by TMHMM2.0 at aa 21-43, 47-69, 286-308, 323-345, 350-372 and 382-404 272560019454 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 272560019455 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560019456 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019457 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.8, E-value 1.3e-07 272560019458 Predicted helix-turn-helix motif with score 1447.000, SD 4.12 at aa 274-295, sequence PTARALAARLHVAEATLRRKLK 272560019459 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560019460 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560019461 active site 272560019462 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 132.7, E-value 4.3e-37 272560019463 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 165.6, E-value 5.3e-47 272560019464 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 271.4, E-value 7.4e-79 272560019465 PS00073 Acyl-CoA dehydrogenases signature 2. 272560019466 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases [Lipid metabolism]; Region: Acs; COG0365 272560019467 Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS); Region: MACS_like_1; cd05974 272560019468 active site 272560019469 acyl-activating enzyme (AAE) consensus motif; other site 272560019470 putative CoA binding site [chemical binding]; other site 272560019471 AMP binding site [chemical binding]; other site 272560019472 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 361.9, E-value 4.3e-106 272560019473 PS00455 AMP-binding domain signature. 272560019474 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 272560019475 tetrameric interface [polypeptide binding]; other site 272560019476 NAD binding site [chemical binding]; other site 272560019477 catalytic residues [active] 272560019478 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 640.4, E-value 6.3e-190 272560019479 PS00070 Aldehyde dehydrogenases cysteine active site. 272560019480 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560019481 3-hydroxyisobutyrate dehydrogenase; Region: HIBADH; TIGR01692 272560019482 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560019483 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score -79.2, E-value 0.00097 272560019484 PS00895 3-hydroxyisobutyrate dehydrogenase signature. 272560019485 enoyl-CoA hydratase; Provisional; Region: PRK09076 272560019486 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560019487 substrate binding site [chemical binding]; other site 272560019488 oxyanion hole (OAH) forming residues; other site 272560019489 trimer interface [polypeptide binding]; other site 272560019490 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 187.0, E-value 2e-53 272560019491 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560019492 3-hydroxyisobutyryl-CoA hydrolase; Provisional; Region: PRK05617 272560019493 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560019494 substrate binding site [chemical binding]; other site 272560019495 oxyanion hole (OAH) forming residues; other site 272560019496 trimer interface [polypeptide binding]; other site 272560019497 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 272560019498 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 122.7, E-value 4.4e-34 272560019499 Signal peptide predicted for BPSS0623 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.452 between residues 31 and 32; signal peptide 272560019500 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560019501 Outer membrane efflux protein; Region: OEP; pfam02321 272560019502 Outer membrane efflux protein; Region: OEP; pfam02321 272560019503 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 66.9, E-value 2.8e-17 272560019504 PS00216 Sugar transport proteins signature 1. 272560019505 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 108.0, E-value 1.2e-29 272560019506 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560019507 macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535 272560019508 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 272560019509 Walker A/P-loop; other site 272560019510 ATP binding site [chemical binding]; other site 272560019511 Q-loop/lid; other site 272560019512 ABC transporter signature motif; other site 272560019513 Walker B; other site 272560019514 D-loop; other site 272560019515 H-loop/switch region; other site 272560019516 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 272560019517 FtsX-like permease family; Region: FtsX; pfam02687 272560019518 Pfam match to entry PF02687 DUF214, Predicted permease , score 145.7, E-value 5.3e-41 272560019519 4 probable transmembrane helices predicted for BPSS0624 by TMHMM2.0 at aa 275-297, 532-554, 581-603 and 613-635 272560019520 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 207.9, E-value 9.9e-60 272560019521 PS00211 ABC transporters family signature. 272560019522 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019523 macrolide transporter subunit MacA; Provisional; Region: PRK11578 272560019524 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560019525 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560019526 1 probable transmembrane helix predicted for BPSS0625 by TMHMM2.0 at aa 43-65 272560019527 Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094 272560019528 active site 272560019529 dimer interface [polypeptide binding]; other site 272560019530 non-prolyl cis peptide bond; other site 272560019531 insertion regions; other site 272560019532 probable oxidoreductase, LLM family; Region: LLM_2I7G; TIGR03858 272560019533 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score -17.7, E-value 2.9e-07 272560019534 Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far. This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases). Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062 272560019535 B1 nucleotide binding pocket [chemical binding]; other site 272560019536 B2 nucleotide binding pocket [chemical binding]; other site 272560019537 CAS motifs; other site 272560019538 active site 272560019539 Pfam match to entry PF00445 ribonuclease_T2, Ribonuclease T2 family , score -14.4, E-value 2.3e-07 272560019540 PS00530 Ribonuclease T2 family histidine active site 1. 272560019541 PS00531 Ribonuclease T2 family histidine active site 2. 272560019542 glutaminase; Provisional; Region: PRK00971 272560019543 PS00012 Phosphopantetheine attachment site. 272560019544 Signal peptide predicted for BPSS0629 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.811 between residues 32 and 33; signal peptide 272560019545 1 probable transmembrane helix predicted for BPSS0629 by TMHMM2.0 at aa 13-32 272560019546 DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701 272560019547 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560019548 active site 272560019549 phosphorylation site [posttranslational modification] 272560019550 intermolecular recognition site; other site 272560019551 dimerization interface [polypeptide binding]; other site 272560019552 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560019553 DNA binding site [nucleotide binding] 272560019554 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 118.1, E-value 1.1e-32 272560019555 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 79.7, E-value 3.8e-21 272560019556 Phosphonate metabolizm protein PhnG; Region: PhnG; cl01454 272560019557 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560019558 dimer interface [polypeptide binding]; other site 272560019559 phosphorylation site [posttranslational modification] 272560019560 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560019561 ATP binding site [chemical binding]; other site 272560019562 Mg2+ binding site [ion binding]; other site 272560019563 G-X-G motif; other site 272560019564 2 probable transmembrane helices predicted for BPSS0631 by TMHMM2.0 at aa 75-97 and 107-129 272560019565 Pfam match to entry PF00672 HAMP, HAMP domain , score 15.7, E-value 0.036 272560019566 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 59.1, E-value 6.2e-15 272560019567 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 93.4, E-value 2.9e-25 272560019568 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 272560019569 Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205 272560019570 active site 272560019571 nucleophile elbow; other site 272560019572 Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244 272560019573 Surface antigen; Region: Bac_surface_Ag; pfam01103 272560019574 1 probable transmembrane helix predicted for BPSS0632 by TMHMM2.0 at aa 737-759 272560019575 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019576 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 146.0, E-value 4.3e-41 272560019577 rod shape-determining protein MreB; Provisional; Region: PRK13930 272560019578 MreB and similar proteins; Region: MreB_like; cd10225 272560019579 nucleotide binding site [chemical binding]; other site 272560019580 Mg binding site [ion binding]; other site 272560019581 putative protofilament interaction site [polypeptide binding]; other site 272560019582 RodZ interaction site [polypeptide binding]; other site 272560019583 Probable gene remnant. Similar to the C-terminal regions of Thiobacillus ferrooxidans cytochrome c-552 precursor Cyc1 SWALL:C552_THIFE (SWALL:P74917) (230 aa) fasta scores: E(): 3.1e-07, 47.94% id in 73 aa, and to Ralstonia solanacearum cytochrome c signal peptide protein RS00629 SWALL:Q8Y2Y4 (EMBL:AL646058) (206 aa) fasta scores: E(): 1.6e-14, 74.62% id in 67 aa;cytochrome c protein (fragment) 272560019584 HD domain; Region: HD_3; pfam13023 272560019585 Pfam match to entry PF01966 HD, HD domain , score 28.4, E-value 1.1e-05 272560019586 N-terminal domain of (some) glycogen debranching enzymes; Region: GDE_N_bis; pfam14742 272560019587 Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408 272560019588 Amylo-alpha-1,6-glucosidase; Region: GDE_C; cl19168 272560019589 Similar to Streptomyces coelicolor lyase SCO5222 or SC7E4.19 SWALL:Q9K499 (EMBL:AL939123) (361 aa) fasta scores: E(): 4.3e-44, 42.35% id in 340 aa, and to Anabaena sp. hypothetical protein alr4685 SWALL:Q8YN85 (EMBL:AP003597) (322 aa) fasta scores: E(): 6.7e-07, 22.75% id in 312 aa CDS contains a frameshifts after codons 2 and 232;conserved hypothetical protein (pseudogene) 272560019590 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_8; cd07246 272560019591 putative dimer interface [polypeptide binding]; other site 272560019592 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 11.4, E-value 0.0038 272560019593 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 39.9, E-value 3.7e-09 272560019594 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560019595 Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570 272560019596 C-terminal domain interface [polypeptide binding]; other site 272560019597 GSH binding site (G-site) [chemical binding]; other site 272560019598 dimer interface [polypeptide binding]; other site 272560019599 C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776 272560019600 N-terminal domain interface [polypeptide binding]; other site 272560019601 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 21.7, E-value 5.1e-06 272560019602 Bacterial protein of unknown function (DUF899); Region: DUF899; pfam05988 272560019603 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560019604 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560019605 dimer interface [polypeptide binding]; other site 272560019606 phosphorylation site [posttranslational modification] 272560019607 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560019608 ATP binding site [chemical binding]; other site 272560019609 Mg2+ binding site [ion binding]; other site 272560019610 G-X-G motif; other site 272560019611 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 124.1, E-value 1.6e-34 272560019612 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 61.3, E-value 1.3e-15 272560019613 Pfam match to entry PF00672 HAMP, HAMP domain , score 23.4, E-value 0.00034 272560019614 1 probable transmembrane helix predicted for BPSS0642 by TMHMM2.0 at aa 20-42 272560019615 DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643 272560019616 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560019617 active site 272560019618 phosphorylation site [posttranslational modification] 272560019619 intermolecular recognition site; other site 272560019620 dimerization interface [polypeptide binding]; other site 272560019621 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560019622 DNA binding site [nucleotide binding] 272560019623 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 88.6, E-value 8.3e-24 272560019624 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 143.3, E-value 2.7e-40 272560019625 PS00217 Sugar transport proteins signature 2. 272560019626 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560019627 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560019628 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560019629 putative active site [active] 272560019630 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 31.0, E-value 3.5e-08 272560019631 Uncharacterized small protein (DUF2158); Region: DUF2158; pfam09926 272560019632 Superinfection immunity protein; Region: Imm_superinfect; pfam14373 272560019633 2 probable transmembrane helices predicted for BPSS0646 by TMHMM2.0 at aa 21-43 and 53-75 272560019634 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 272560019635 active site residue [active] 272560019636 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 42.4, E-value 6.8e-10 272560019637 PS00380 Rhodanese signature 1. 272560019638 transcriptional activator FtrA; Provisional; Region: ftrA; PRK09393 272560019639 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 272560019640 conserved cys residue [active] 272560019641 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019642 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 77.3, E-value 2.1e-20 272560019643 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 30.9, E-value 1.9e-06 272560019644 Predicted helix-turn-helix motif with score 1719.000, SD 5.04 at aa 229-250, sequence HTLASLAARAAMSPRTLQRQFR 272560019645 PS00041 Bacterial regulatory proteins, araC family signature. 272560019646 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 33.9, E-value 2.4e-07 272560019647 hypothetical protein; Provisional; Region: PRK08201 272560019648 Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_5; cd05682 272560019649 metal binding site [ion binding]; metal-binding site 272560019650 putative dimer interface [polypeptide binding]; other site 272560019651 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 54.6, E-value 1.4e-13 272560019652 TfoX N-terminal domain; Region: TfoX_N; pfam04993 272560019653 NnrU protein; Region: NnrU; pfam07298 272560019654 6 probable transmembrane helices predicted for BPSS0652 by TMHMM2.0 at aa 20-42, 59-81, 91-113, 120-139, 144-163 and 184-206 272560019655 Possible gene remnant. Similar to an internal region of Rhodobacter capsulatus insertion element protein SWALL:O68064 (EMBL:AF010496) (191 aa) fasta scores: E(): 1.3, 38.75% id in 80 aa 272560019656 Genomic island GI 14 272560019657 Probable gene remnant. Similar to the C-terminal regions of Pseudomonas aeruginosa transposase for transposon Tn501 TnpA SWALL:TNP5_PSEAE (SWALL:P06695) (988 aa) fasta scores: E(): 1.4e-08, 47.43% id in 78 aa, and to Pseudomonas putida Tn4653 transposase TnpA SWALL:Q8VMH0 (EMBL:AJ344068) (988 aa) fasta scores: E(): 5.6e-09, 48.68% id in 76 aa;transposase (fragment) 272560019658 x-prolyl-dipeptidyl aminopeptidase; Provisional; Region: PRK05371 272560019659 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530 272560019660 Pfam match to entry PF02129 Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family) , score 20.2, E-value 1.6e-07 272560019661 Pfam match to entry PF02129 Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family) , score 65.2, E-value 5e-22 272560019662 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 272560019663 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 272560019664 PS00131 Serine carboxypeptidases, serine active site. 272560019665 Probable gene remnant. Similar to the C-terminal regions of Burkholderia pseudomallei transposase B SWALL:Q9EZL2 (EMBL:AF287634) (284 aa) fasta scores: E(): 2.2e-07, 41.91% id in 136 aa, and Ralstonia solanacearum ISRSO16-transposase OrfB protein rsp0558 or rs03921 SWALL:Q8XSC0 (EMBL:AL646079) (280 aa) fasta scores: E(): 1.9e-05, 36.84% id in 133 aa;transposase (fragment) 272560019666 Signal peptide predicted for BPSS0658 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.951 between residues 30 and 31; signal peptide 272560019667 VirK protein; Region: VirK; pfam06903 272560019668 Similar to the N-terminal regions of Agrobacterium tumefaciens plasmid pTIBO542, insertion sequence IS1312 Orf1 and Orf2 genes SWALL:Q44320 (EMBL:U19148) (130 aa) fasta scores: E(): 0.89, 24.09% id in 83 aa, and Ralstonia solanacearum ISRSO10-transposase OrfA protein rsc1831 or rs04265 SWALL:Q8XYC7 (EMBL:AL646066) (121 aa) fasta scores: E(): 1.3, 25.3% id in 83 aa;insertion sequence protein (fragment) 272560019669 Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 34-55, sequence TTVAEASRAYDLSPSEIENWVD 272560019670 Similar to Ralstonia solanacearum ISRso16-transposase orfB protein rsp0558 or rs03921 SWALL:Q8XSC0 (EMBL:AL646079) (280 aa) fasta scores: E(): 1e-14, 32.33% id in 266 aa. C-terminal region is similar to Rhodobacter capsulatus insertion element SWALL:O68064 (EMBL:AF010496) (191 aa) fasta scores: E(): 2.1e-47, 66.84% id in 190 aa. Contains a frameshift after codon 191. Possible alternative translational start site; insertion element protein (pseudogene) 272560019671 Predicted helix-turn-helix motif with score 981.000, SD 2.53 at aa 32-53, sequence VSISKLCRWFEVPRRTMYYRPV 272560019672 Predicted helix-turn-helix motif with score 981.000, SD 2.53 at aa 77-53, sequence VKSEPKVQARFAEPIKALIEESPSF 272560019673 Predicted helix-turn-helix motif with score 1565.000, SD 4.52 at aa 77-98, sequence FGYRTLAHLLGFNKNTVQRIFR 272560019674 Pfam match to entry PF00665 rve, Integrase core domain , score 57.0, E-value 2e-16 272560019675 Pfam match to entry PF00665 rve, Integrase core domain , score 45.5, E-value 4.2e-13 272560019676 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560019677 Signal peptide predicted for BPSS0663 by SignalP 2.0 HMM (Signal peptide probability 0.830) with cleavage site probability 0.317 between residues 23 and 24; signal peptide 272560019678 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560019679 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078 272560019680 active site 272560019681 intermolecular recognition site; other site 272560019682 dimerization interface [polypeptide binding]; other site 272560019683 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560019684 DNA binding site [nucleotide binding] 272560019685 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score -4.4, E-value 0.0012 272560019686 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 38.3, E-value 1.2e-08 272560019687 Similar to the C-terminal region of Pseudomonas aeruginosa probable sensor/response regulator hybrid pa2824 SWALL:Q9I019 (EMBL:AE004709) (786 aa) fasta scores: E(): 4.8e-06, 31.45% id in 124 aa, and to the full length Brucella abortus response regulator DivK SWALL:Q9RHA3 (EMBL:AF051940) (123 aa) fasta scores: E(): 0.0011, 29.06% id in 117 aa; response regulator protein (fragment) 272560019688 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560019689 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 272560019690 active site 272560019691 iron coordination sites [ion binding]; other site 272560019692 substrate binding pocket [chemical binding]; other site 272560019693 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 278.0, E-value 8e-81 272560019694 Signal peptide predicted for BPSS0666 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.987 between residues 29 and 30; signal peptide 272560019695 Peptidase family M9 N-terminal; Region: Peptidase_M9_N; pfam08453 272560019696 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 272560019697 Pfam match to entry PF01752 Peptidase_M9, Collagenase , score 340.9, E-value 9e-100 272560019698 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560019699 Probable gene remnant. No significant database matches to the full length CDS. N-terminal region is similar to Xanthomonas axonopodis hypothetical protein xac2350 SWALL:Q8PK27 (EMBL:AE011872) (151 aa) fasta scores: E(): 1e-19, 48.2% id in 139 aa, and to Ralstonia solanacearum hypothetical protein rsc2436 or rs02667 SWALL:Q8XWN7 (EMBL:AL646070) (165 aa) fasta scores: E(): 6.1e-17, 43.5% id in 154 aa. CDS lacks an appropriate translational start codon.;acetyltransferase (GNAT) family protein (fragment) 272560019700 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 24.8, E-value 0.00013 272560019701 Protein of unknown function (DUF1653); Region: DUF1653; pfam07866 272560019702 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214 272560019703 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560019704 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560019705 putative substrate translocation pore; other site 272560019706 14 probable transmembrane helices predicted for BPSS0670 by TMHMM2.0 at aa 19-41, 67-89, 96-118, 122-144, 157-179, 183-205, 218-237, 247-266, 287-309, 314-333, 345-367, 371-393, 414-436 and 451-468 272560019707 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 26.0, E-value 6.3e-08 272560019708 Trehalase; Region: Trehalase; cl17346 272560019709 Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626 272560019710 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560019711 Pfam match to entry PF01204 Trehalase, Trehalase , score 604.3, E-value 4.9e-179 272560019712 PS00927 Trehalase signature 1. 272560019713 PS00928 Trehalase signature 2. 272560019714 6 probable transmembrane helices predicted for BPSS0672 by TMHMM2.0 at aa 12-34, 58-80, 87-109, 135-157, 169-190 and 200-222 272560019715 Heme-copper oxidase subunit III. Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cl00211 272560019716 Subunit I/III interface [polypeptide binding]; other site 272560019717 Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III , score -162.8, E-value 1.4e-06 272560019718 5 probable transmembrane helices predicted for BPSS0673 by TMHMM2.0 at aa 37-59, 72-94, 109-126, 147-169 and 189-208 272560019719 Prokaryotic Cytochrome C oxidase subunit IV; Region: COX4_pro; pfam03626 272560019720 3 probable transmembrane helices predicted for BPSS0674 by TMHMM2.0 at aa 21-40, 44-66 and 75-97 272560019721 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560019722 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560019723 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560019724 DNA binding residues [nucleotide binding] 272560019725 dimerization interface [polypeptide binding]; other site 272560019726 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 33.6, E-value 3e-07 272560019727 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560019728 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315 272560019729 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560019730 dimerization interface [polypeptide binding]; other site 272560019731 DNA binding residues [nucleotide binding] 272560019732 exosortase A system-associated amidotransferase 1; Region: eps_aminotran_1; TIGR03108 272560019733 Glutamine amidotransferases class-II (GATase) asparagine synthase_B type. Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a glutaminase domain and a...; Region: AsnB; cd00712 272560019734 active site 272560019735 dimer interface [polypeptide binding]; other site 272560019736 The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B catalyzes the...; Region: Asn_Synthase_B_C; cd01991 272560019737 Ligand Binding Site [chemical binding]; other site 272560019738 Molecular Tunnel; other site 272560019739 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 52.1, E-value 8e-13 272560019740 Pfam match to entry PF00733 Asn_synthase, Asparagine synthase , score 187.7, E-value 1.2e-53 272560019741 Probable gene remnant that contains additional sequence at the C-terminus. No significant database matches to the full length CDS. N-terminal region is similar to the C-terminal regions of Ralstonia solanacearum probable two-component system response regulator transcription regulator protein rsc1073 or rs04004 SWALL:Q8Y0H1 (EMBL:AL646062) (237 aa) fasta scores: E(): 1.8e-09, 38.94% id in 95 aa, and Thermoanaerobacter tengcongensis response regulators consisting of a CheY-like receiver domain and a HTH DNA-binding domain tte0774 SWALL:Q8RBP2 (EMBL:AE013044) (224 aa) fasta scores: E(): 7e-08, 41.41% id in 99 aa;response regulator protein (fragment) 272560019742 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 64.5, E-value 1.5e-16 272560019743 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529 272560019744 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 272560019745 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008 272560019746 Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738 272560019747 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain , score -140.9, E-value 1.2e-09 272560019748 Pfam match to entry PF01315 Ald_Xan_dh_C, Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain , score -17.2, E-value 0.00035 272560019749 Pfam match to entry PF02738 Ald_Xan_dh_C2, Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain , score 18.1, E-value 1.7e-05 272560019750 PS00430 TonB-dependent receptor proteins signature 1. 272560019751 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080 272560019752 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560019753 catalytic loop [active] 272560019754 iron binding site [ion binding]; other site 272560019755 [2Fe-2S] binding domain; Region: Fer2_2; pfam01799 272560019756 Pfam match to entry PF01799 fer2_2, [2Fe-2S] binding domain , score 122.9, E-value 4e-34 272560019757 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 42.0, E-value 8.8e-10 272560019758 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560019759 AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719 272560019760 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560019761 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019762 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 46.9, E-value 2.9e-11 272560019763 Predicted helix-turn-helix motif with score 1557.000, SD 4.49 at aa 233-254, sequence LRVETLAQQVNMSVSSLHHHFK 272560019764 PS00041 Bacterial regulatory proteins, araC family signature. 272560019765 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 26.6, E-value 3.7e-05 272560019766 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560019767 Protein of unknown function (DUF3564); Region: DUF3564; pfam12087 272560019768 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 272560019769 Dibenzothiophene (DBT) desulfurization enzyme C; Region: DszC; cd01163 272560019770 Flavin binding site [chemical binding]; other site 272560019771 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score -8.4, E-value 7e-05 272560019772 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 272560019773 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560019774 active site 272560019775 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score -12.0, E-value 0.00012 272560019776 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 272560019777 active site 272560019778 non-prolyl cis peptide bond; other site 272560019779 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560019780 dimerization interface [polypeptide binding]; other site 272560019781 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560019782 dimer interface [polypeptide binding]; other site 272560019783 phosphorylation site [posttranslational modification] 272560019784 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560019785 ATP binding site [chemical binding]; other site 272560019786 Mg2+ binding site [ion binding]; other site 272560019787 G-X-G motif; other site 272560019788 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 130.3, E-value 2.3e-36 272560019789 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 49.1, E-value 6.4e-12 272560019790 Pfam match to entry PF00672 HAMP, HAMP domain , score 48.7, E-value 8.5e-12 272560019791 2 probable transmembrane helices predicted for BPSS0687 by TMHMM2.0 at aa 5-27 and 133-155 272560019792 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560019793 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560019794 active site 272560019795 phosphorylation site [posttranslational modification] 272560019796 intermolecular recognition site; other site 272560019797 dimerization interface [polypeptide binding]; other site 272560019798 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560019799 DNA binding site [nucleotide binding] 272560019800 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 79.2, E-value 5.7e-21 272560019801 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 121.9, E-value 7.5e-34 272560019802 Signal peptide predicted for BPSS0689 by SignalP 2.0 HMM (Signal peptide probability 0.967) with cleavage site probability 0.937 between residues 25 and 26; signal peptide 272560019803 MltA-interacting protein MipA; Region: MipA; cl01504 272560019804 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560019805 Male sterility protein; Region: NAD_binding_4; pfam07993 272560019806 NAD(P) binding site [chemical binding]; other site 272560019807 active site 272560019808 MarR family; Region: MarR_2; cl17246 272560019809 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560019810 Pfam match to entry PF01047 MarR, MarR family , score 73.5, E-value 2.9e-19 272560019811 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 272560019812 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 59.5, E-value 4.7e-15 272560019813 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303 272560019814 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560019815 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 253.9, E-value 1.4e-73 272560019816 Human aldehyde dehydrogenase family 8 member A1-like; Region: ALDH_F8_HMSADH; cd07093 272560019817 NAD binding site [chemical binding]; other site 272560019818 catalytic residues [active] 272560019819 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 634.3, E-value 4.3e-188 272560019820 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560019821 PS00070 Aldehyde dehydrogenases cysteine active site. 272560019822 The Class III extradiol dioxygenase, homoprotocatechuate 2,3-dioxygenase, catalyzes the key ring cleavage step in the metabolism of homoprotocatechuate; Region: HPCD; cd07370 272560019823 putative active site [active] 272560019824 putative metal binding site [ion binding]; other site 272560019825 Pfam match to entry PF02900 LigB, Catalytic LigB subunit of aromatic ring-opening dioxygenase , score 221.3, E-value 9.2e-64 272560019826 5-carboxymethyl-2-hydroxymuconate isomerase (CHMI) is a trimeric enzyme catalyzing the isomerization of the unsaturated ketone 5-(carboxymethyl)-2-hydroxymuconate to 5-(carboxymethyl)-2-oxo-3-hexene-1,6-dionate. This is one step in the...; Region: CHMI; cd00580 272560019827 putative substrate binding pocket [chemical binding]; other site 272560019828 trimer interface [polypeptide binding]; other site 272560019829 Pfam match to entry PF02962 CHMI, 5-carboxymethyl-2-hydroxymuconate isomerase , score 217.3, E-value 1.5e-62 272560019830 PS00995 Chaperonins TCP-1 signature 3. 272560019831 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 272560019832 Pfam match to entry PF01689 Hyratase_decarb, Hydratase/decarboxylase , score 452.1, E-value 3.2e-133 272560019833 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 272560019834 Pfam match to entry PF03328 HpcH_HpaI, HpcH/HpaI aldolase , score 496.1, E-value 1.8e-146 272560019835 Helix-turn-helix domain; Region: HTH_18; pfam12833 272560019836 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560019837 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 37.4, E-value 2.1e-08 272560019838 PS00041 Bacterial regulatory proteins, araC family signature. 272560019839 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 11.8, E-value 0.14 272560019840 Predicted helix-turn-helix motif with score 1146.000, SD 3.09 at aa 174-195, sequence RRADEWAAWAGMAPRTLSRRFV 272560019841 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 272560019842 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560019843 NAD(P) binding site [chemical binding]; other site 272560019844 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 46.8, E-value 3.1e-11 272560019845 PS00430 TonB-dependent receptor proteins signature 1. 272560019846 Signal peptide predicted for BPSS0701 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 45 and 46; signal peptide 272560019847 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560019848 trimer interface [polypeptide binding]; other site 272560019849 eyelet of channel; other site 272560019850 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -60.7, E-value 0.00072 272560019851 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560019852 ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259 272560019853 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 272560019854 Walker A/P-loop; other site 272560019855 ATP binding site [chemical binding]; other site 272560019856 Q-loop/lid; other site 272560019857 ABC transporter signature motif; other site 272560019858 Walker B; other site 272560019859 D-loop; other site 272560019860 H-loop/switch region; other site 272560019861 TOBE domain; Region: TOBE_2; pfam08402 272560019862 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 212.6, E-value 3.8e-61 272560019863 PS00211 ABC transporters family signature. 272560019864 PS00017 ATP/GTP-binding site motif A (P-loop). 272560019865 ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178 272560019866 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560019867 dimer interface [polypeptide binding]; other site 272560019868 conserved gate region; other site 272560019869 putative PBP binding loops; other site 272560019870 ABC-ATPase subunit interface; other site 272560019871 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560019872 dimer interface [polypeptide binding]; other site 272560019873 conserved gate region; other site 272560019874 putative PBP binding loops; other site 272560019875 ABC-ATPase subunit interface; other site 272560019876 13 probable transmembrane helices predicted for BPSS0703 by TMHMM2.0 at aa 58-80, 113-135, 148-170, 190-212, 250-272, 295-317, 348-370, 409-431, 444-466, 476-493, 528-546, 551-573 and 580-602 272560019877 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 29.3, E-value 6e-06 272560019878 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560019879 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 30.8, E-value 2e-06 272560019880 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560019881 Signal peptide predicted for BPSS0704 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.789 between residues 21 and 22; signal peptide 272560019882 ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840 272560019883 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 38.5, E-value 9.9e-09 272560019884 transcriptional regulatory protein TctD; Provisional; Region: PRK15479 272560019885 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560019886 active site 272560019887 phosphorylation site [posttranslational modification] 272560019888 intermolecular recognition site; other site 272560019889 dimerization interface [polypeptide binding]; other site 272560019890 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560019891 DNA binding site [nucleotide binding] 272560019892 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 145.1, E-value 7.9e-41 272560019893 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 59.4, E-value 5.1e-15 272560019894 Two-component sensor kinase N-terminal; Region: 2CSK_N; pfam08521 272560019895 HAMP domain; Region: HAMP; pfam00672 272560019896 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560019897 dimer interface [polypeptide binding]; other site 272560019898 phosphorylation site [posttranslational modification] 272560019899 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560019900 ATP binding site [chemical binding]; other site 272560019901 Mg2+ binding site [ion binding]; other site 272560019902 G-X-G motif; other site 272560019903 2 probable transmembrane helices predicted for BPSS0706 by TMHMM2.0 at aa 10-29 and 162-184 272560019904 Pfam match to entry PF00672 HAMP, HAMP domain , score 42.5, E-value 6e-10 272560019905 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 57.9, E-value 1.4e-14 272560019906 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 117.2, E-value 2.1e-32 272560019907 Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217 272560019908 MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476 272560019909 MOSC domain; Region: MOSC; pfam03473 272560019910 Pfam match to entry PF03473 MOSC, MOSC domain , score 58.5, E-value 9.4e-15 272560019911 Pfam match to entry PF03476 MOSC_N, MOSC N-terminal beta barrel domain , score 166.4, E-value 3.1e-47 272560019912 Signal peptide predicted for BPSS0708 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.959 between residues 22 and 23; signal peptide 272560019913 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560019914 trimer interface [polypeptide binding]; other site 272560019915 eyelet of channel; other site 272560019916 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -44.1, E-value 0.00016 272560019917 Transposase domain (DUF772); Region: DUF772; pfam05598 272560019918 Transposase DDE domain; Region: DDE_Tnp_1; pfam01609 272560019919 Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751 272560019920 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score -2.6, E-value 0.0072 272560019921 enoyl-CoA hydratase; Validated; Region: PRK08139 272560019922 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560019923 substrate binding site [chemical binding]; other site 272560019924 oxyanion hole (OAH) forming residues; other site 272560019925 trimer interface [polypeptide binding]; other site 272560019926 2-enoyl-CoA Hydratase C-terminal region; Region: ECH_C; pfam13766 272560019927 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 129.7, E-value 3.4e-36 272560019928 alanine racemase; Reviewed; Region: PRK13340 272560019929 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827 272560019930 active site 272560019931 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560019932 substrate binding site [chemical binding]; other site 272560019933 catalytic residues [active] 272560019934 dimer interface [polypeptide binding]; other site 272560019935 Pfam match to entry PF00842 Ala_racemase, Alanine racemase , score 474.3, E-value 6.4e-140 272560019936 PS00395 Alanine racemase pyridoxal-phosphate attachment site. 272560019937 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2343 272560019938 ergothioneine biosynthesis protein EgtB; Region: egtB_TIGR03440 272560019939 DinB superfamily; Region: DinB_2; pfam12867 272560019940 Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582 272560019941 Pfam match to entry PF03781 DUF323, Domain of unknown function (DUF323) , score 58.0, E-value 1.3e-14 272560019942 dimethylhistidine N-methyltransferase; Region: egtD_ergothio; TIGR03438 272560019943 Histidine-specific methyltransferase, SAM-dependent; Region: Methyltransf_33; pfam10017 272560019944 Signal peptide predicted for BPSS0715 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 33 and 34; signal peptide 272560019945 Protein of unknown function (DUF3455); Region: DUF3455; pfam11937 272560019946 Esterase/lipase [General function prediction only]; Region: COG1647 272560019947 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560019948 MASE1; Region: MASE1; cl17823 272560019949 PAS fold; Region: PAS_3; pfam08447 272560019950 9 probable transmembrane helices predicted for BPSS0717 by TMHMM2.0 at aa 10-32, 39-56, 80-102, 114-136, 151-173, 186-204, 214-236, 241-258 and 273-290 272560019951 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560019952 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560019953 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 55.5, E-value 7.4e-14 272560019954 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 272560019955 Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Escherichia coli Hsp31 protein; Region: GATase1_Hsp31_like; cd03141 272560019956 potential catalytic triad [active] 272560019957 conserved cys residue [active] 272560019958 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 90.5, E-value 2.2e-24 272560019959 Old yellow enzyme (OYE) YqjM-like FMN binding domain. YqjM is involved in the oxidative stress response of Bacillus subtilis. Like the other OYE members, each monomer of YqjM contains FMN as a non-covalently bound cofactor and uses NADPH as a reducing...; Region: OYE_YqiM_FMN; cd02932 272560019960 active site 272560019961 FMN binding site [chemical binding]; other site 272560019962 substrate binding site [chemical binding]; other site 272560019963 homotetramer interface [polypeptide binding]; other site 272560019964 catalytic residue [active] 272560019965 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 243.5, E-value 2e-70 272560019966 Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623 272560019967 Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372 272560019968 NAD binding site [chemical binding]; other site 272560019969 homotetramer interface [polypeptide binding]; other site 272560019970 homodimer interface [polypeptide binding]; other site 272560019971 substrate binding site [chemical binding]; other site 272560019972 active site 272560019973 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 19.9, E-value 1.1e-08 272560019974 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560019975 Probable gene remnant. Similar to Chromobacterium violaceum probable acetyltransferase CV2792 SWALL:Q7NUB0 (EMBL:AE016919) (141 aa) fasta scores: E(): 1.7e-21, 47.05% id in 136 aa. CDS lacks appropriate translational start and stop codons. CDS is extended at the C-terminus in comparison to similar proteins; acetyltransferase (fragment) 272560019976 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 272560019977 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20 , score 61.1, E-value 1.6e-15 272560019978 8 probable transmembrane helices predicted for BPSS0723 by TMHMM2.0 at aa 20-37, 44-58, 73-95, 169-191, 222-244, 251-273, 283-305 and 318-340 272560019979 Signal peptide predicted for BPSS0724 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.374 between residues 48 and 49; signal peptide 272560019980 SmpA / OmlA family; Region: SmpA_OmlA; cl19285 272560019981 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560019982 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560019983 NAD(P) binding site [chemical binding]; other site 272560019984 active site 272560019985 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 192.5, E-value 4.4e-55 272560019986 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560019987 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560019988 DNA-binding site [nucleotide binding]; DNA binding site 272560019989 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560019990 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560019991 homodimer interface [polypeptide binding]; other site 272560019992 catalytic residue [active] 272560019993 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 33.5, E-value 3.2e-07 272560019994 Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467 272560019995 Probable gene remnant. Similar to the C-terminal regions of Burkholderia pseudomallei sensor protein IrlS SWALL:IRLS_BURPS (SWALL:O31396) (464 aa) fasta scores: E(): 5e-16, 34.37% id in 192 aa, and Pseudomonas aeruginosa probable two-component sensor pa1438 SWALL:Q9I3Q9 (EMBL:AE004573) (481 aa) fasta scores: E(): 2.1e-35, 54.63% id in 216 aa. CDS contains a frameshift mutation after codon 127;sensor kinase (fragment) 272560019996 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 29.7, E-value 2.8e-08 272560019997 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 12.7, E-value 0.0019 272560019998 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 9.4, E-value 0.005 272560019999 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664 272560020000 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560020001 ligand binding site [chemical binding]; other site 272560020002 flexible hinge region; other site 272560020003 Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545 272560020004 Predicted helix-turn-helix motif with score 1923.000, SD 5.74 at aa 184-205, sequence ISQEELGMLVGVSRQRINQALQ 272560020005 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 24.2, E-value 0.00019 272560020006 acyl-CoA synthetase; Validated; Region: PRK08162 272560020007 Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles and Arabidopsis; Region: ttLC_FACS_AEE21_like; cd12118 272560020008 acyl-activating enzyme (AAE) consensus motif; other site 272560020009 putative active site [active] 272560020010 AMP binding site [chemical binding]; other site 272560020011 putative CoA binding site [chemical binding]; other site 272560020012 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 325.9, E-value 3e-95 272560020013 PS00455 AMP-binding domain signature. 272560020014 Cache domain; Region: Cache_1; pfam02743 272560020015 HAMP domain; Region: HAMP; pfam00672 272560020016 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560020017 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560020018 dimer interface [polypeptide binding]; other site 272560020019 putative CheW interface [polypeptide binding]; other site 272560020020 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 275.3, E-value 5.2e-80 272560020021 Pfam match to entry PF00672 HAMP, HAMP domain , score 27.6, E-value 1.9e-05 272560020022 2 probable transmembrane helices predicted for BPSS0733 by TMHMM2.0 at aa 28-50 and 344-363 272560020023 Signal peptide predicted for BPSS0734 by SignalP 2.0 HMM (Signal peptide probability 0.946) with cleavage site probability 0.370 between residues 30 and 31; signal peptide 272560020024 copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837 272560020025 outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781 272560020026 Outer membrane efflux protein; Region: OEP; pfam02321 272560020027 Outer membrane efflux protein; Region: OEP; pfam02321 272560020028 Uncharacterized conserved protein [Function unknown]; Region: COG1615; cl09133 272560020029 Wnt and FGF inhibitory regulator; Region: Shisa; pfam13908 272560020030 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 135.7, E-value 5.4e-38 272560020031 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 130.0, E-value 2.8e-36 272560020032 CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421 272560020033 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560020034 DXD motif; other site 272560020035 PilZ domain; Region: PilZ; pfam07238 272560020036 8 probable transmembrane helices predicted for BPSS0735 by TMHMM2.0 at aa 5-27, 40-58, 73-95, 381-400, 410-432, 445-464, 479-501 and 513-535 272560020037 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 77.7, E-value 1.6e-20 272560020038 Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566 272560020039 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560020040 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560020041 1 probable transmembrane helix predicted for BPSS0737 by TMHMM2.0 at aa 43-65 272560020042 Predicted helix-turn-helix motif with score 1065.000, SD 2.81 at aa 96-117, sequence FILSSLAARRDIHPRTLRTIFK 272560020043 ChrR Cupin-like domain; Region: Cupin_7; pfam12973 272560020044 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560020045 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020046 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560020047 dimerization interface [polypeptide binding]; other site 272560020048 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 86.7, E-value 3e-23 272560020049 PS00030 Eukaryotic RNA-binding region RNP-1 signature. 272560020050 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 56.9, E-value 2.8e-14 272560020051 Predicted helix-turn-helix motif with score 1203.000, SD 3.28 at aa 33-54, sequence GGMAAAELELNIGISTISRHVK 272560020052 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560020053 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560020054 inhibitor-cofactor binding pocket; inhibition site 272560020055 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560020056 catalytic residue [active] 272560020057 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 431.1, E-value 6.3e-127 272560020058 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560020059 Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085 272560020060 tetrameric interface [polypeptide binding]; other site 272560020061 NAD binding site [chemical binding]; other site 272560020062 catalytic residues [active] 272560020063 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 515.8, E-value 2e-152 272560020064 Gene remnant. Similar to the N-terminal regions of Burkholderia cepacia insertion element IS402 hypothetical protein SWALL:YI22_BURCE (SWALL:P24537) (147 aa) fasta scores: E(): 5.4e-16, 59.49% id in 79 aa, and Pseudomonas glumae transposase SWALL:Q9KW00 (EMBL:AB046460) (136 aa) fasta scores: E(): 6.2e-13, 55.84% id in 77 aa;insertion element protein (fragment) 272560020065 Signal peptide predicted for BPSS0746 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 28 and 29; signal peptide 272560020066 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560020067 Secretory lipase; Region: LIP; pfam03583 272560020068 Pfam match to entry PF03583 LIP, Secretory lipase , score -0.3, E-value 4.2e-11 272560020069 Predicted helix-turn-helix motif with score 1200.000, SD 3.27 at aa 237-258, sequence RHRADDAEHSKLHRSVIHNILR 272560020070 Signal peptide predicted for BPSS0747 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 24 and 25; signal peptide 272560020071 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020072 trimer interface [polypeptide binding]; other site 272560020073 eyelet of channel; other site 272560020074 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -64.6, E-value 0.001 272560020075 Signal peptide predicted for BPSS0748 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.981 between residues 21 and 22; signal peptide 272560020076 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 272560020077 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 272560020078 Pfam match to entry PF03640 Lipoprotein_15, Secreted repeat of unknown function , score 45.4, E-value 8.4e-11 272560020079 Pfam match to entry PF03640 Lipoprotein_15, Secreted repeat of unknown function , score 40.4, E-value 2.7e-09 272560020080 RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937 272560020081 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560020082 DNA binding residues [nucleotide binding] 272560020083 dimerization interface [polypeptide binding]; other site 272560020084 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 73.8, E-value 2.3e-19 272560020085 PS00622 Bacterial regulatory proteins, luxR family signature. 272560020086 Predicted helix-turn-helix motif with score 1225.000, SD 3.36 at aa 241-262, sequence NSSKAIAERLAISPETVKVHRR 272560020087 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 272560020088 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560020089 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -222.1, E-value 0.00023 272560020090 12 probable transmembrane helices predicted for BPSS0750 by TMHMM2.0 at aa 46-68, 72-94, 115-137, 152-174, 179-201, 221-243, 264-286, 318-340, 361-383, 388-410, 423-445 and 455-472 272560020091 L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253 272560020092 homodimer interface [polypeptide binding]; other site 272560020093 homotetramer interface [polypeptide binding]; other site 272560020094 active site pocket [active] 272560020095 cleavage site 272560020096 Pfam match to entry PF03576 Peptidase_T4, Peptidase T4 , score 319.8, E-value 2.1e-93 272560020097 Signal peptide predicted for BPSS0752 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.639 between residues 25 and 26; signal peptide 272560020098 Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399 272560020099 Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cl11399 272560020100 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560020101 Fusaric acid resistance protein family; Region: FUSC; pfam04632 272560020102 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 272560020103 10 probable transmembrane helices predicted for BPSS0754 by TMHMM2.0 at aa 37-59, 86-108, 113-130, 137-159, 169-191, 406-428, 457-476, 483-505, 510-532 and 537-559 272560020104 transcriptional regulator; Provisional; Region: PRK10632 272560020105 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020106 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560020107 putative effector binding pocket; other site 272560020108 dimerization interface [polypeptide binding]; other site 272560020109 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 67.2, E-value 2.3e-17 272560020110 Predicted helix-turn-helix motif with score 1122.000, SD 3.01 at aa 17-38, sequence GSFTAAAQSLNSTTGAMSRAVS 272560020111 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 164.8, E-value 9.4e-47 272560020112 Signal peptide predicted for BPSS0756 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.989 between residues 22 and 23; signal peptide 272560020113 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560020114 Signal peptide predicted for BPSS0757 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 21 and 22; signal peptide 272560020115 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020116 trimer interface [polypeptide binding]; other site 272560020117 eyelet of channel; other site 272560020118 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -88.1, E-value 0.0089 272560020119 PS00572 Glycosyl hydrolases family 1 active site. 272560020120 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_14; cd08355 272560020121 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 10.7, E-value 0.0062 272560020122 cytosine permease; Provisional; Region: codB; PRK11017 272560020123 Na binding site [ion binding]; other site 272560020124 Pfam match to entry PF02133 Transp_cyt_pur, Permease for cytosine/purines, uracil, thiamine, allantoin , score -13.7, E-value 3.5e-07 272560020125 12 probable transmembrane helices predicted for BPSS0759 by TMHMM2.0 at aa 19-41, 56-78, 99-121, 126-148, 155-174, 189-211, 232-254, 258-280, 306-323, 327-349, 362-384 and 388-405 272560020126 Purine catabolism regulatory protein-like family; Region: PucR; pfam07905 272560020127 phosphoribosyl-dephospho-CoA transferase; Provisional; Region: PRK02098; cl07913 272560020128 PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556 272560020129 Predicted helix-turn-helix motif with score 1305.000, SD 3.63 at aa 353-374, sequence GNAIKAAEQLSIHRNTLNHRLR 272560020130 Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293 272560020131 cytosine deaminase; Provisional; Region: PRK05985 272560020132 active site 272560020133 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 272560020134 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020135 putative substrate translocation pore; other site 272560020136 12 probable transmembrane helices predicted for BPSS0762 by TMHMM2.0 at aa 23-41, 56-78, 91-113, 123-145, 152-174, 184-206, 255-277, 287-309, 322-341, 345-367, 379-401 and 411-429 272560020137 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 272560020138 short chain dehydrogenase; Provisional; Region: PRK12829 272560020139 classical (c) SDRs; Region: SDR_c; cd05233 272560020140 NAD(P) binding site [chemical binding]; other site 272560020141 active site 272560020142 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 244.9, E-value 7.3e-71 272560020143 PS00196 Type-1 copper (blue) proteins signature. 272560020144 PS00061 Short-chain dehydrogenases/reductases family signature. 272560020145 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560020146 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 272560020147 DNA-binding site [nucleotide binding]; DNA binding site 272560020148 FCD domain; Region: FCD; pfam07729 272560020149 Predicted helix-turn-helix motif with score 1092.000, SD 2.91 at aa 109-130, sequence LSLRSVAEAVGSSTMPVRAALT 272560020150 Putative ClC chloride channel. Clc proteins are putative halogen ion (Cl-, Br- and I-) transporters found in eubacteria. They belong to the ClC superfamily of halogen ion channels, which share a unique double-barreled architecture and voltage-dependent...; Region: ClC_like; cd01033 272560020151 putative ion selectivity filter; other site 272560020152 putative pore gating glutamate residue; other site 272560020153 Pfam match to entry PF00654 voltage_CLC, Voltage gated chloride channel , score -61.4, E-value 1.1e-09 272560020154 7 probable transmembrane helices predicted for BPSS0766 by TMHMM2.0 at aa 134-156, 163-185, 195-217, 238-260, 275-297, 304-326 and 367-385 272560020155 H-type lectin domain; Region: H_lectin; pfam09458 272560020156 RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169 272560020157 Signal peptide predicted for BPSS0769 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.984 between residues 26 and 27; signal peptide 272560020158 Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657 272560020159 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560020160 Pfam match to entry PF00326 Peptidase_S9, Prolyl oligopeptidase , score 12.9, E-value 0.00067 272560020161 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560020162 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560020163 active site 272560020164 phosphorylation site [posttranslational modification] 272560020165 intermolecular recognition site; other site 272560020166 dimerization interface [polypeptide binding]; other site 272560020167 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560020168 DNA binding residues [nucleotide binding] 272560020169 dimerization interface [polypeptide binding]; other site 272560020170 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 75.0, E-value 1e-19 272560020171 Predicted helix-turn-helix motif with score 1476.000, SD 4.21 at aa 164-185, sequence DTPADIAQALGISAKTVRIYKA 272560020172 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 64.7, E-value 1.3e-16 272560020173 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560020174 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560020175 Pfam match to entry PF01047 MarR, MarR family , score 58.5, E-value 9.4e-15 272560020176 Gene remnant. Similar to the C-terminal regions of Azospirillum brasilense galactose-binding protein regulator GbpR SWALL:GBPR_AZOBR (SWALL:P52661) (342 aa) fasta scores: E(): 3.4e-15, 30.36% id in 191 aa, and Xanthomonas campestris galactose-binding protein regulator xcc1748 SWALL:Q8P9U9 (EMBL:AE012276) (323 aa) fasta scores: E(): 2.1e-20, 37.3% id in 193 aa. CDS contains a frameshift mutation after codon 54;LysR family regulatory protein (fragment) 272560020177 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 53.6, E-value 1.4e-14 272560020178 Gene remnant. Similar to the C-terminal regions of Escherichia coli, and Shigella flexneri L-arabinose transport system permease AraH SWALL:ARAH_ECOLI (SWALL:P08532) (329 aa) fasta scores: E(): 7.8e-39, 48% id in 250 aa, and Ralstonia solanacearum probable L-arabinose transmembrane ABC transporter protein rsc2756 or rs00098 SWALL:Q8XVS3 (EMBL:AL646071) (335 aa) fasta scores: E(): 9.5e-40, 50.61% id in 243 aa. CDS contains a frameshift mutation after codon 116; sugar transport system permease (fragment) 272560020179 4 probable transmembrane helices predicted for BPSS0774 by TMHMM2.0 at aa 19-36, 40-62, 69-87 and 107-129 272560020180 2 probable transmembrane helices predicted for BPSS0775 by TMHMM2.0 at aa 7-29 and 39-61 272560020181 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 272560020182 Pfam match to entry PF03758 SMP-30, Senescence marker protein-30 (SMP-30) , score 243.1, E-value 2.6e-70 272560020183 Protein of unknown function (DUF861); Region: Cupin_3; cl17594 272560020184 Uncharacterized conserved protein [Function unknown]; Region: COG5649 272560020185 p-hydroxycinnamoyl CoA hydratase/lyase; Validated; Region: PRK09120 272560020186 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560020187 substrate binding site [chemical binding]; other site 272560020188 oxyanion hole (OAH) forming residues; other site 272560020189 trimer interface [polypeptide binding]; other site 272560020190 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 163.0, E-value 3.4e-46 272560020191 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560020192 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560020193 NAD(P) binding site [chemical binding]; other site 272560020194 catalytic residues [active] 272560020195 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 449.6, E-value 1.8e-132 272560020196 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560020197 feruloyl-CoA synthase; Reviewed; Region: PRK08180 272560020198 Feruloyl-CoA synthetase (FCS); Region: FCS; cd05921 272560020199 acyl-activating enzyme (AAE) consensus motif; other site 272560020200 putative AMP binding site [chemical binding]; other site 272560020201 putative active site [active] 272560020202 putative CoA binding site [chemical binding]; other site 272560020203 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 193.6, E-value 2e-55 272560020204 putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551 272560020205 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020206 putative substrate translocation pore; other site 272560020207 12 probable transmembrane helices predicted for BPSS0782 by TMHMM2.0 at aa 39-61, 76-98, 110-129, 133-155, 168-190, 195-217, 247-269, 284-306, 313-335, 339-361, 374-396 and 401-423 272560020208 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -30.3, E-value 9.5e-07 272560020209 PS00216 Sugar transport proteins signature 1. 272560020210 PS00217 Sugar transport proteins signature 2. 272560020211 Signal peptide predicted for BPSS0783 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.898 between residues 22 and 23; signal peptide 272560020212 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020213 trimer interface [polypeptide binding]; other site 272560020214 eyelet of channel; other site 272560020215 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -78.1, E-value 0.0036 272560020216 Tannase and feruloyl esterase; Region: Tannase; pfam07519 272560020217 PS01323 Phosphotriesterase signature 2. 272560020218 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560020219 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560020220 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560020221 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 10.0, E-value 3.8e-09 272560020222 Predicted helix-turn-helix motif with score 1335.000, SD 3.73 at aa 72-93, sequence LTRTEITKELGRNASEIYRMLE 272560020223 Signal peptide predicted for BPSS0786 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.970 between residues 27 and 28; signal peptide 272560020224 Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536 272560020225 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560020226 ligand binding site [chemical binding]; other site 272560020227 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -45.2, E-value 0.011 272560020228 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 272560020229 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560020230 Walker A/P-loop; other site 272560020231 ATP binding site [chemical binding]; other site 272560020232 Q-loop/lid; other site 272560020233 ABC transporter signature motif; other site 272560020234 Walker B; other site 272560020235 D-loop; other site 272560020236 H-loop/switch region; other site 272560020237 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560020238 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 151.6, E-value 8.9e-43 272560020239 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020240 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 79.8, E-value 3.7e-21 272560020241 PS00211 ABC transporters family signature. 272560020242 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560020243 TM-ABC transporter signature motif; other site 272560020244 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -44.8, E-value 0.00012 272560020245 10 probable transmembrane helices predicted for BPSS0788 by TMHMM2.0 at aa 31-53, 57-79, 91-113, 117-139, 146-163, 183-205, 234-256, 266-283, 288-310 and 315-337 272560020246 Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613 272560020247 D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295 272560020248 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560020249 active site 272560020250 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 272560020251 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560020252 NAD(P) binding site [chemical binding]; other site 272560020253 active site 272560020254 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 240.5, E-value 1.6e-69 272560020255 PS00061 Short-chain dehydrogenases/reductases family signature. 272560020256 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 272560020257 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560020258 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 271.8, E-value 5.8e-79 272560020259 short chain dehydrogenase; Provisional; Region: PRK08628 272560020260 classical (c) SDRs; Region: SDR_c; cd05233 272560020261 NAD(P) binding site [chemical binding]; other site 272560020262 active site 272560020263 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 201.5, E-value 8.4e-58 272560020264 Domain of unknown function (DUF718); Region: DUF718; pfam05336 272560020265 Signal peptide predicted for BPSS0786 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.970 between residues 18 and 19; signal peptide 272560020266 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020267 trimer interface [polypeptide binding]; other site 272560020268 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560020269 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020270 trimer interface [polypeptide binding]; other site 272560020271 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020272 trimer interface [polypeptide binding]; other site 272560020273 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560020274 trimer interface [polypeptide binding]; other site 272560020275 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560020276 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 47.8, E-value 1.6e-11 272560020277 H-NS histone family; Region: Histone_HNS; pfam00816 272560020278 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560020279 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560020280 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560020281 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560020282 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 72.4, E-value 6.2e-19 272560020283 1 probable transmembrane helix predicted for BPSS0797 by TMHMM2.0 at aa 60-82 272560020284 Predicted helix-turn-helix motif with score 1340.000, SD 3.75 at aa 24-45, sequence LGVTRLASKLGINKSRTYRMLC 272560020285 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560020286 Pfam match to entry PF00563 EAL, EAL domain , score -11.8, E-value 6.2e-10 272560020287 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560020288 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560020289 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 69.6, E-value 4.4e-18 272560020290 Predicted helix-turn-helix motif with score 1218.000, SD 3.34 at aa 38-59, sequence TTIEMIRERCDTSVGNIYHHFG 272560020291 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560020292 CoenzymeA binding site [chemical binding]; other site 272560020293 subunit interaction site [polypeptide binding]; other site 272560020294 PHB binding site; other site 272560020295 Signal peptide predicted for BPSS0802 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.866 between residues 27 and 28; signal peptide 272560020296 Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342 272560020297 dimerization interface [polypeptide binding]; other site 272560020298 Receptor family ligand binding region; Region: ANF_receptor; pfam01094 272560020299 ligand binding site [chemical binding]; other site 272560020300 Pfam match to entry PF01094 ANF_receptor, Receptor family ligand binding region , score 70.3, E-value 2.6e-18 272560020301 channel protein, hemolysin III family; Region: hlyIII; TIGR01065 272560020302 Pfam match to entry PF03006 UPF0073, Uncharacterised protein family (Hly-III / UPF0073) , score -68.6, E-value 3.8e-05 272560020303 7 probable transmembrane helices predicted for BPSS0803 by TMHMM2.0 at aa 12-34, 44-63, 83-100, 105-127, 132-154, 158-180 and 187-209 272560020304 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560020305 MHYT domain (predicted integral membrane sensor domain) [Signal transduction mechanisms]; Region: COG3300 272560020306 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 272560020307 Bacterial signalling protein N terminal repeat; Region: MHYT; pfam03707 272560020308 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560020309 metal binding site [ion binding]; metal-binding site 272560020310 active site 272560020311 I-site; other site 272560020312 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560020313 Pfam match to entry PF00563 EAL, EAL domain , score 356.7, E-value 1.7e-104 272560020314 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 227.2, E-value 1.5e-65 272560020315 7 probable transmembrane helices predicted for BPSS0805 by TMHMM2.0 at aa 5-27, 39-61, 76-98, 105-124, 139-161, 174-196 and 211-233 272560020316 Pfam match to entry PF03707 SPNTR, Bacterial signalling protein N terminal repeat , score 66.7, E-value 3.3e-17 272560020317 Pfam match to entry PF03707 SPNTR, Bacterial signalling protein N terminal repeat , score 42.5, E-value 6.1e-10 272560020318 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560020319 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560020320 putative DNA binding site [nucleotide binding]; other site 272560020321 putative Zn2+ binding site [ion binding]; other site 272560020322 AsnC family; Region: AsnC_trans_reg; pfam01037 272560020323 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 102.6, E-value 5e-28 272560020324 Predicted helix-turn-helix motif with score 1031.000, SD 2.70 at aa 32-53, sequence ISNLELAKAVGLSPAQTLRRHR 272560020325 aromatic amino acid transporter; Provisional; Region: PRK10238 272560020326 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 681.2, E-value 3.3e-202 272560020327 12 probable transmembrane helices predicted for BPSS0807 by TMHMM2.0 at aa 21-40, 44-61, 98-120, 124-146, 153-175, 198-220, 240-262, 282-304, 331-353, 357-379, 399-421 and 426-443 272560020328 PS00218 Amino acid permeases signature. 272560020329 Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155 272560020330 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560020331 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560020332 homodimer interface [polypeptide binding]; other site 272560020333 catalytic residue [active] 272560020334 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 291.6, E-value 6.2e-85 272560020335 PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 272560020336 Protein of unknown function, DUF488; Region: DUF488; cl01246 272560020337 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560020338 Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583 272560020339 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 29.7, E-value 4.4e-06 272560020340 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 272560020341 Pfam match to entry PF03171 2OG-FeII_Oxy, 2OG-Fe(II) oxygenase superfamily , score 18.5, E-value 0.0007 272560020342 Circularly permuted ATP-grasp type 2; Region: CP_ATPgrasp_2; cl17448 272560020343 Signal peptide predicted for BPSS0802 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.866 between residues 27 and 28; signal peptide 272560020344 Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852 272560020345 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560020346 putative active site [active] 272560020347 heme pocket [chemical binding]; other site 272560020348 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560020349 dimer interface [polypeptide binding]; other site 272560020350 phosphorylation site [posttranslational modification] 272560020351 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560020352 ATP binding site [chemical binding]; other site 272560020353 G-X-G motif; other site 272560020354 Pfam match to entry PF00989 PAS, PAS domain , score 29.1, E-value 1.2e-07 272560020355 PS00678 Trp-Asp (WD) repeats signature. 272560020356 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 14.1, E-value 0.0015 272560020357 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 119.4, E-value 4.4e-33 272560020358 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560020359 active site 272560020360 phosphorylation site [posttranslational modification] 272560020361 intermolecular recognition site; other site 272560020362 dimerization interface [polypeptide binding]; other site 272560020363 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 76.4, E-value 3.8e-20 272560020364 Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776 272560020365 CheC-like family; Region: CheC; pfam04509 272560020366 penicillin-binding protein 1C; Region: PBP_1c; TIGR02073 272560020367 Transglycosylase; Region: Transgly; pfam00912 272560020368 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560020369 Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832 272560020370 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score -23.6, E-value 8e-09 272560020371 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 106.9, E-value 2.5e-29 272560020372 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 0.2, E-value 5e+02 272560020373 3 probable transmembrane helices predicted for BPSS0816 by TMHMM2.0 at aa 13-35, 39-61 and 68-90 272560020374 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 2.4, E-value 2.6e+02 272560020375 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 2.4, E-value 2.6e+02 272560020376 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 2.3, E-value 2.7e+02 272560020377 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 1.0, E-value 4e+02 272560020378 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 1.2, E-value 3.8e+02 272560020379 Pfam match to entry PF03093 Nucleoporin_FG, Nucleoporin FG repeat family , score 1.2, E-value 3.8e+02 272560020380 Bacterial Ig-like domain; Region: Big_5; pfam13205 272560020381 Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373 272560020382 MG2 domain; Region: A2M_N; pfam01835 272560020383 Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703 272560020384 Alpha-2-macroglobulin family; Region: A2M; pfam00207 272560020385 This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267 272560020386 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020387 Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523 272560020388 GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661 272560020389 putative active site pocket [active] 272560020390 dimerization interface [polypeptide binding]; other site 272560020391 putative catalytic residue [active] 272560020392 leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390 272560020393 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 272560020394 active site 272560020395 nucleotide binding site [chemical binding]; other site 272560020396 HIGH motif; other site 272560020397 KMSKS motif; other site 272560020398 Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020 272560020399 tRNA binding surface [nucleotide binding]; other site 272560020400 anticodon binding site; other site 272560020401 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score 153.3, E-value 2.7e-43 272560020402 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560020403 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560020404 S-adenosylmethionine binding site [chemical binding]; other site 272560020405 P-aminobenzoate N-oxygenase AurF; Region: AurF; pfam11583 272560020406 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560020407 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560020408 substrate binding pocket [chemical binding]; other site 272560020409 active site 272560020410 iron coordination sites [ion binding]; other site 272560020411 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 135.5, E-value 6.2e-38 272560020412 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560020413 S-adenosylmethionine binding site [chemical binding]; other site 272560020414 Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520 272560020415 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560020416 catalytic residue [active] 272560020417 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score -8.3, E-value 5.1e-08 272560020418 Signal peptide predicted for BPSS0827 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.946 between residues 29 and 30; signal peptide 272560020419 Peptidase family M9 N-terminal; Region: Peptidase_M9_N; pfam08453 272560020420 Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813 272560020421 Pfam match to entry PF01752 Peptidase_M9, Collagenase , score 322.6, E-value 3e-94 272560020422 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560020423 Signal peptide predicted for BPSS0828 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 29 and 30; signal peptide 272560020424 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560020425 putative monooxygenase; Reviewed; Region: PRK07045 272560020426 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560020427 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 70.9, E-value 1.7e-18 272560020428 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560020429 salt bridge; other site 272560020430 non-specific DNA binding site [nucleotide binding]; other site 272560020431 sequence-specific DNA binding site [nucleotide binding]; other site 272560020432 Cupin domain; Region: Cupin_2; pfam07883 272560020433 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 38.7, E-value 8.6e-09 272560020434 Predicted helix-turn-helix motif with score 1258.000, SD 3.47 at aa 21-42, sequence KTLLEVATEANLSVGFLSQVER 272560020435 Protein of unknown function (DUF2964); Region: DUF2964; pfam11177 272560020436 2 probable transmembrane helices predicted for BPSS0831 by TMHMM2.0 at aa 7-29 and 34-56 272560020437 Protein of unknown function (DUF1488); Region: DUF1488; pfam07369 272560020438 PS00153 ATP synthase gamma subunit signature. 272560020439 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560020440 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560020441 active site 272560020442 phosphorylation site [posttranslational modification] 272560020443 intermolecular recognition site; other site 272560020444 dimerization interface [polypeptide binding]; other site 272560020445 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560020446 DNA binding residues [nucleotide binding] 272560020447 dimerization interface [polypeptide binding]; other site 272560020448 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 81.7, E-value 9.6e-22 272560020449 Predicted helix-turn-helix motif with score 1662.000, SD 4.85 at aa 164-185, sequence QTLTQIADELCVSAKTVSTYKT 272560020450 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 146.3, E-value 3.6e-41 272560020451 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020452 Ligand Binding Site [chemical binding]; other site 272560020453 Pfam match to entry PF00582 Usp, Universal stress protein family , score 56.0, E-value 5.2e-14 272560020454 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020455 Ligand Binding Site [chemical binding]; other site 272560020456 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020457 Ligand Binding Site [chemical binding]; other site 272560020458 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020459 Ligand Binding Site [chemical binding]; other site 272560020460 Pfam match to entry PF00582 Usp, Universal stress protein family , score 66.1, E-value 5e-17 272560020461 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020462 Ligand Binding Site [chemical binding]; other site 272560020463 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020464 Ligand Binding Site [chemical binding]; other site 272560020465 formaldehyde dehydrogenase (FDH)-like; Region: FDH_like_ADH2; cd08286 272560020466 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560020467 catalytic Zn binding site [ion binding]; other site 272560020468 structural Zn binding site [ion binding]; other site 272560020469 NAD(P) binding site [chemical binding]; other site 272560020470 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 262.9, E-value 2.8e-76 272560020471 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560020472 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 272560020473 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125 272560020474 active site residue [active] 272560020475 Pfam match to entry PF00597 DedA, DedA family , score 11.5, E-value 0.0004 272560020476 6 probable transmembrane helices predicted for BPSS0841 by TMHMM2.0 at aa 12-34, 49-71, 83-105, 137-159, 164-186 and 201-223 272560020477 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020478 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560020479 putative substrate translocation pore; other site 272560020480 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -92.5, E-value 0.00014 272560020481 9 probable transmembrane helices predicted for BPSS0842 by TMHMM2.0 at aa 34-56, 152-169, 174-193, 223-245, 255-277, 284-306, 311-333, 346-368 and 372-394 272560020482 PS00216 Sugar transport proteins signature 1. 272560020483 PS00217 Sugar transport proteins signature 2. 272560020484 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560020485 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 272560020486 NAD(P) binding site [chemical binding]; other site 272560020487 active site 272560020488 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 61.0, E-value 1.7e-15 272560020489 1 probable transmembrane helix predicted for BPSS0843 by TMHMM2.0 at aa 13-30 272560020490 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 272560020491 Spore germination protein; Region: Spore_permease; cl17796 272560020492 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 577.8, E-value 4.6e-171 272560020493 12 probable transmembrane helices predicted for BPSS0845 by TMHMM2.0 at aa 16-38, 42-64, 83-105, 125-147, 154-176, 198-220, 240-262, 282-304, 331-353, 357-379, 400-422 and 427-446 272560020494 PS00218 Amino acid permeases signature. 272560020495 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560020496 Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396 272560020497 non-specific DNA binding site [nucleotide binding]; other site 272560020498 salt bridge; other site 272560020499 sequence-specific DNA binding site [nucleotide binding]; other site 272560020500 H-NS histone family; Region: Histone_HNS; pfam00816 272560020501 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560020502 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 272560020503 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560020504 active site 272560020505 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score -29.6, E-value 0.0021 272560020506 4 probable transmembrane helices predicted for BPSS0848 by TMHMM2.0 at aa 20-42, 72-89, 96-118 and 128-150 272560020507 PS00211 ABC transporters family signature. 272560020508 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560020509 1 probable transmembrane helix predicted for BPSS0849 by TMHMM2.0 at aa 198-220 272560020510 Protein of unknown function (DUF3088); Region: DUF3088; pfam11287 272560020511 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 272560020512 active site 272560020513 non-prolyl cis peptide bond; other site 272560020514 NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These...; Region: nuc_hydro_CaPnhB; cd02650 272560020515 active site 272560020516 Pfam match to entry PF01156 IU_nuc_hydro, Inosine-uridine preferring nucleoside hydrolase , score 198.5, E-value 6.6e-57 272560020517 Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174 272560020518 substrate binding site [chemical binding]; other site 272560020519 dimer interface [polypeptide binding]; other site 272560020520 ATP binding site [chemical binding]; other site 272560020521 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 231.0, E-value 1.1e-66 272560020522 PS00583 pfkB family of carbohydrate kinases signature 1. 272560020523 Signal peptide predicted for BPSS0854 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.628 between residues 25 and 26; signal peptide 272560020524 This model contains proteins with the VRR-NUC domain; Region: VRR_NUC; smart00990 272560020525 Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199 272560020526 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560020527 ATP binding site [chemical binding]; other site 272560020528 DEAD_2; Region: DEAD_2; pfam06733 272560020529 Helicase C-terminal domain; Region: Helicase_C_2; pfam13307 272560020530 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020531 Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011 272560020532 L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196 272560020533 Similar to the N-terminal regions of Bacillus stearothermophilus N-carbamoyl-L-amino acid hydrolase AmaB SWALL:AMB1_BACST (SWALL:P37113) (409 aa) fasta scores: E(): 2.3e-18, 41.17% id in 170 aa, and to Pseudomonas putida N-carbamoyl-beta-alanine amidohydrolase PP4034 SWALL:AAN69626 (EMBL:AE016789) (427 aa) fasta scores: E(): 8.7e-35, 53.57% id in 196 aa. Contains a frameshift after codon 69;N-carbamoyl-L-amino acid hydrolase (fragment) 272560020534 Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465 272560020535 flagellar capping protein; Reviewed; Region: fliD; PRK08032 272560020536 Flagellin hook IN motif; Region: Flagellin_IN; pfam07196 272560020537 Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195 272560020538 Pfam match to entry PF02465 FliD, Flagellar hook-associated protein 2 , score 134.1, E-value 1.7e-37 272560020539 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020540 transcriptional regulator; Provisional; Region: PRK10632 272560020541 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020542 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560020543 putative effector binding pocket; other site 272560020544 dimerization interface [polypeptide binding]; other site 272560020545 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 187.1, E-value 1.8e-53 272560020546 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 60.2, E-value 2.8e-15 272560020547 PS00044 Bacterial regulatory proteins, lysR family signature. 272560020548 Predicted helix-turn-helix motif with score 1178.000, SD 3.20 at aa 17-38, sequence GSVSAAAQHLDMSRAMASRYVA 272560020549 DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the...; Region: DsbA_FrnE_like; cd03025 272560020550 catalytic residues [active] 272560020551 Similar to internal regions of Rhizobium loti probable transcriptional regulator mlr2579 SWALL:Q98I42 (EMBL:AP003000) (304 aa) fasta scores: E(): 5.2e-06, 34.72% id in 144 aa, and to Rhizobium loti transcriptional regulator mlr7163 SWALL:Q986Y1 (EMBL:AP003011) (300 aa) fasta scores: E(): 0.00014, 34.35% id in 131 aa;hypothetical protein (fragment) 272560020552 Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660 272560020553 voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293 272560020554 active site 272560020555 catalytic tetrad [active] 272560020556 Pfam match to entry PF00248 aldo_ket_red, Aldo/keto reductase , score 188.0, E-value 9.8e-54 272560020557 Molybdenum cofactor biosynthesis protein F; Region: MoaF; pfam10703 272560020558 Signal peptide predicted for BPSS0866 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.587 between residues 26 and 27; signal peptide 272560020559 short chain dehydrogenase; Provisional; Region: PRK07774 272560020560 classical (c) SDRs; Region: SDR_c; cd05233 272560020561 NAD(P) binding site [chemical binding]; other site 272560020562 active site 272560020563 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 232.0, E-value 5.4e-67 272560020564 PS00061 Short-chain dehydrogenases/reductases family signature. 272560020565 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560020566 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560020567 DNA binding residues [nucleotide binding] 272560020568 dimerization interface [polypeptide binding]; other site 272560020569 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 47.4, E-value 2.1e-11 272560020570 PS00622 Bacterial regulatory proteins, luxR family signature. 272560020571 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560020572 NAD(P) binding site [chemical binding]; other site 272560020573 catalytic residues [active] 272560020574 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 661.8, E-value 2.4e-196 272560020575 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560020576 PS00070 Aldehyde dehydrogenases cysteine active site. 272560020577 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560020578 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560020579 inhibitor-cofactor binding pocket; inhibition site 272560020580 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560020581 catalytic residue [active] 272560020582 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 427.5, E-value 7.6e-126 272560020583 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560020584 Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531 272560020585 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560020586 13 probable transmembrane helices predicted for BPSS0870 by TMHMM2.0 at aa 24-46, 53-75, 85-107, 114-136, 151-170, 182-204, 219-241, 254-273, 308-330, 360-377, 387-409, 421-443 and 453-475 272560020587 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -226.6, E-value 0.00031 272560020588 Protein of unknown function (DUF3156); Region: DUF3156; pfam11354 272560020589 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560020590 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 17.4, E-value 0.022 272560020591 PS00041 Bacterial regulatory proteins, araC family signature. 272560020592 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 22.4, E-value 0.00072 272560020593 Signal peptide predicted for BPSS0873 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.678 between residues 21 and 22; signal peptide 272560020594 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020595 trimer interface [polypeptide binding]; other site 272560020596 eyelet of channel; other site 272560020597 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -82.9, E-value 0.0056 272560020598 Signal peptide predicted for BPSS0875 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.953 between residues 25 and 26; signal peptide 272560020599 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560020600 Pfam match to entry PF01810 LysE, LysE type translocator , score 42.6, E-value 5.6e-10 272560020601 5 probable transmembrane helices predicted for BPSS0875 by TMHMM2.0 at aa 7-29, 44-66, 71-93, 113-135 and 148-170 272560020602 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560020603 Coenzyme A binding pocket [chemical binding]; other site 272560020604 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 57.4, E-value 2e-14 272560020605 Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933 272560020606 FMN binding site [chemical binding]; other site 272560020607 active site 272560020608 substrate binding site [chemical binding]; other site 272560020609 catalytic residue [active] 272560020610 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 285.2, E-value 5.3e-83 272560020611 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560020612 dimerization interface [polypeptide binding]; other site 272560020613 putative DNA binding site [nucleotide binding]; other site 272560020614 putative Zn2+ binding site [ion binding]; other site 272560020615 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 53.1, E-value 4e-13 272560020616 Predicted helix-turn-helix motif with score 1425.000, SD 4.04 at aa 43-64, sequence VCAGQIDALCGLSQSTVSAHLA 272560020617 Signal peptide predicted for BPSS0879 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21; signal peptide 272560020618 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020619 trimer interface [polypeptide binding]; other site 272560020620 eyelet of channel; other site 272560020621 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -14.7, E-value 1.1e-05 272560020622 nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753 272560020623 Rnk N-terminus; Region: Rnk_N; pfam14760 272560020624 Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272 272560020625 Pfam match to entry PF01272 GreA_GreB, Prokaryotic transcription elongation factor, GreA/GreB, C-terminal domain , score 26.8, E-value 3.2e-05 272560020626 Signal peptide predicted for BPSS0881 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.834 between residues 24 and 25; signal peptide 272560020627 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560020628 FOG: CBS domain [General function prediction only]; Region: COG0517 272560020629 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_10; cd04623 272560020630 Pfam match to entry PF00571 CBS, CBS domain , score 61.3, E-value 1.4e-15 272560020631 Pfam match to entry PF00571 CBS, CBS domain , score 36.8, E-value 3.3e-08 272560020632 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 272560020633 dimerization interface [polypeptide binding]; other site 272560020634 active site 272560020635 Pfam match to entry PF00925 GTP_cyclohydro2, GTP cyclohydrolase II , score 316.9, E-value 1.5e-92 272560020636 Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase; cl00205 272560020637 NADH/NADPH cofactor binding site [chemical binding]; other site 272560020638 Autoinducer synthetase; Region: Autoind_synth; cl17404 272560020639 Pfam match to entry PF00765 Autoind_synth, Autoinducer synthetase , score 35.0, E-value 1e-11 272560020640 DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188 272560020641 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560020642 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560020643 DNA binding residues [nucleotide binding] 272560020644 dimerization interface [polypeptide binding]; other site 272560020645 Pfam match to entry PF03472 Autoind_bind, Autoinducer binding domain , score 153.8, E-value 1.9e-43 272560020646 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 86.3, E-value 3.9e-23 272560020647 PS00622 Bacterial regulatory proteins, luxR family signature. 272560020648 Predicted helix-turn-helix motif with score 1403.000, SD 3.97 at aa 191-212, sequence KTACEIGQILSISERTVNFHVN 272560020649 Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285 272560020650 MgtC family; Region: MgtC; pfam02308 272560020651 Pfam match to entry PF02308 MgtC, MgtC family , score 158.8, E-value 5.9e-45 272560020652 4 probable transmembrane helices predicted for BPSS0888 by TMHMM2.0 at aa 5-22, 29-51, 56-78 and 91-113 272560020653 Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385 272560020654 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560020655 putative active site [active] 272560020656 putative metal binding site [ion binding]; other site 272560020657 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 65.1, E-value 9.7e-17 272560020658 4 probable transmembrane helices predicted for BPSS0889 by TMHMM2.0 at aa 7-24, 34-56, 69-91 and 111-133 272560020659 Nitroreductase-like family 5. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148 272560020660 putative FMN binding site [chemical binding]; other site 272560020661 Pfam match to entry PF00881 Nitroreductase, Nitroreductase , score 45.4, E-value 8.3e-11 272560020662 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_2; pfam13532 272560020663 Pfam match to entry PF03171 2OG-FeII_Oxy, 2OG-Fe(II) oxygenase superfamily , score 30.9, E-value 2e-06 272560020664 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 272560020665 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560020666 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560020667 Predicted helix-turn-helix motif with score 1042.000, SD 2.74 at aa 68-89, sequence LSAPELSKRIGIPRTTTFRLLQ 272560020668 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 124.6, E-value 1.2e-34 272560020669 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020670 trimer interface [polypeptide binding]; other site 272560020671 eyelet of channel; other site 272560020672 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -56.8, E-value 0.00051 272560020673 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 272560020674 [2Fe-2S] cluster binding site [ion binding]; other site 272560020675 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 83.1, E-value 3.7e-22 272560020676 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 272560020677 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560020678 iron-sulfur cluster [ion binding]; other site 272560020679 [2Fe-2S] cluster binding site [ion binding]; other site 272560020680 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 272560020681 hydrophobic ligand binding site; other site 272560020682 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 94.4, E-value 1.5e-25 272560020683 short chain dehydrogenase; Provisional; Region: PRK12939 272560020684 classical (c) SDRs; Region: SDR_c; cd05233 272560020685 NAD(P) binding site [chemical binding]; other site 272560020686 active site 272560020687 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 218.0, E-value 9.4e-63 272560020688 PS00061 Short-chain dehydrogenases/reductases family signature. 272560020689 Cupin domain; Region: Cupin_2; pfam07883 272560020690 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560020691 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560020692 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 63.7, E-value 2.7e-16 272560020693 helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346 272560020694 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560020695 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560020696 Predicted helix-turn-helix motif with score 1389.000, SD 3.92 at aa 51-72, sequence LGAPELSKRLGIPRTTVFRLLQ 272560020697 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 105.5, E-value 6.7e-29 272560020698 short chain dehydrogenase; Provisional; Region: PRK07062 272560020699 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560020700 NAD(P) binding site [chemical binding]; other site 272560020701 active site 272560020702 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 199.5, E-value 3.4e-57 272560020703 hypothetical protein; Provisional; Region: PRK07064 272560020704 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560020705 PYR/PP interface [polypeptide binding]; other site 272560020706 dimer interface [polypeptide binding]; other site 272560020707 TPP binding site [chemical binding]; other site 272560020708 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560020709 Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cd00568 272560020710 TPP-binding site [chemical binding]; other site 272560020711 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 128.8, E-value 6.5e-36 272560020712 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 31.6, E-value 7.5e-08 272560020713 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560020714 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 87.8, E-value 1.4e-23 272560020715 L-aspartate dehydrogenase; Provisional; Region: PRK13303 272560020716 Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447 272560020717 Domain of unknown function DUF108; Region: DUF108; pfam01958 272560020718 Pfam match to entry PF01958 DUF108, Domain of unknown function DUF108 , score 140.4, E-value 2.1e-39 272560020719 Uncharacterized Candidatus pelagibacter aldehyde dehydrogenase, DhaS-like; Region: ALDH_DhaS; cd07114 272560020720 NAD(P) binding site [chemical binding]; other site 272560020721 catalytic residues [active] 272560020722 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 632.8, E-value 1.2e-187 272560020723 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560020724 PS00070 Aldehyde dehydrogenases cysteine active site. 272560020725 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 272560020726 active site 272560020727 metal binding site [ion binding]; metal-binding site 272560020728 3,4-dihydroxyphenylacetate 2,3-dioxygenase; Region: HpaD; TIGR02295 272560020729 C-terminal domain of Burkholderia sp. NF100 MhqB and similar proteins; MhqB is a type I extradiol dioxygenase involved in the catabolism of methylhydroquinone, an intermediate in the degradation of fenitrothion; Region: MhqB_like_C; cd08360 272560020730 putative active site [active] 272560020731 putative metal binding site [ion binding]; other site 272560020732 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 42.6, E-value 5.7e-10 272560020733 phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754 272560020734 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560020735 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560020736 Reductase C-terminal; Region: Reductase_C; pfam14759 272560020737 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 263.5, E-value 1.9e-76 272560020738 benzoate transport; Region: 2A0115; TIGR00895 272560020739 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020740 putative substrate translocation pore; other site 272560020741 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 117.3, E-value 1.8e-32 272560020742 12 probable transmembrane helices predicted for BPSS0907 by TMHMM2.0 at aa 51-73, 83-105, 112-134, 138-160, 172-194, 199-221, 287-309, 324-343, 350-372, 376-398, 411-430 and 440-462 272560020743 PS00217 Sugar transport proteins signature 2. 272560020744 PS00216 Sugar transport proteins signature 1. 272560020745 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020746 trimer interface [polypeptide binding]; other site 272560020747 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560020748 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020749 trimer interface [polypeptide binding]; other site 272560020750 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560020751 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020752 trimer interface [polypeptide binding]; other site 272560020753 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560020754 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560020755 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560020756 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560020757 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 118.0, E-value 1.1e-32 272560020758 Signal peptide predicted for BPSS0909 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.596 between residues 30 and 31; signal peptide 272560020759 SmpA / OmlA family; Region: SmpA_OmlA; pfam04355 272560020760 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560020761 ligand binding site [chemical binding]; other site 272560020762 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560020763 Pfam match to entry PF00691 OmpA, OmpA family , score 88.1, E-value 1.2e-23 272560020764 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560020765 Ligand Binding Site [chemical binding]; other site 272560020766 amidase; Provisional; Region: PRK07486 272560020767 Pfam match to entry PF01425 Amidase, Amidase , score 325.6, E-value 3.7e-95 272560020768 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020769 PS00571 Amidases signature. 272560020770 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560020771 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560020772 dimerization interface [polypeptide binding]; other site 272560020773 putative DNA binding site [nucleotide binding]; other site 272560020774 putative Zn2+ binding site [ion binding]; other site 272560020775 AsnC family; Region: AsnC_trans_reg; pfam01037 272560020776 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 145.0, E-value 8.4e-41 272560020777 PS00519 Bacterial regulatory proteins, asnC family signature. 272560020778 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 272560020779 homodimer interface [polypeptide binding]; other site 272560020780 substrate-cofactor binding pocket; other site 272560020781 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560020782 catalytic residue [active] 272560020783 Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme , score 379.7, E-value 1.9e-111 272560020784 Signal peptide predicted for BPSS0915 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.988 between residues 28 and 29; signal peptide 272560020785 N-acetyltransferase; Region: Acetyltransf_2; pfam00797 272560020786 Pfam match to entry PF00797 Acetyltransf2, N-acetyltransferase , score 83.3, E-value 3.2e-22 272560020787 Putative glycolipid-binding; Region: Glycolipid_bind; pfam06475 272560020788 Transcriptional regulator; Region: Rrf2; pfam02082 272560020789 Rrf2 family protein; Region: rrf2_super; TIGR00738 272560020790 Pfam match to entry PF02082 UPF0074, Uncharacterized protein family UPF0074 , score 6.8, E-value 2e-06 272560020791 Predicted helix-turn-helix motif with score 1120.000, SD 3.00 at aa 40-61, sequence ATSEAIAKMLGTNPVVVRRMMA 272560020792 Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492 272560020793 Gene remnant. Similar to internal regions of Nitrosomonas europaea ATCC 19718 integrase, catalytic core SWALL:Q82T33 (EMBL:BX321863) (204 aa) fasta scores: E(): 3.4e-08, 84.21% id in 38 aa, and Bacteriophage phiE125 TnpB SWALL:Q8W6R2 (EMBL:AF447491) (284 aa) fasta scores: E(): 4.5e-08, 84.21% id in 38 aa; transposase (fragment) 272560020794 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560020795 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020796 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560020797 dimerization interface [polypeptide binding]; other site 272560020798 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 128.6, E-value 7.5e-36 272560020799 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 93.0, E-value 3.9e-25 272560020800 PS00044 Bacterial regulatory proteins, lysR family signature. 272560020801 Predicted helix-turn-helix motif with score 1580.000, SD 4.57 at aa 23-44, sequence GSLAAASQQLHVAVSAISRQIA 272560020802 Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_2; cd05679 272560020803 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624 272560020804 metal binding site [ion binding]; metal-binding site 272560020805 putative dimer interface [polypeptide binding]; other site 272560020806 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 117.1, E-value 2.2e-32 272560020807 citrate-proton symporter; Provisional; Region: PRK15075 272560020808 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020809 putative substrate translocation pore; other site 272560020810 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 117.0, E-value 2.4e-32 272560020811 12 probable transmembrane helices predicted for BPSS0922 by TMHMM2.0 at aa 12-34, 54-76, 83-102, 106-128, 148-170, 185-202, 231-253, 268-290, 302-324, 329-351, 363-385 and 395-412 272560020812 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560020813 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560020814 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 67.2, E-value 2.3e-17 272560020815 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560020816 1 probable transmembrane helix predicted for BPSS0924 by TMHMM2.0 at aa 187-209 272560020817 Signal peptide predicted for BPSS0925 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.910 between residues 23 and 24; signal peptide 272560020818 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560020819 short chain dehydrogenase; Provisional; Region: PRK08267 272560020820 NAD(P) binding site [chemical binding]; other site 272560020821 active site 272560020822 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 165.2, E-value 7.2e-47 272560020823 PS00061 Short-chain dehydrogenases/reductases family signature. 272560020824 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 272560020825 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 272560020826 Pfam match to entry PF00743 FMO-like, Flavin-binding monooxygenase-like , score -52.9, E-value 1.1e-20 272560020827 YhhN-like protein; Region: YhhN; pfam07947 272560020828 6 probable transmembrane helices predicted for BPSS0927 by TMHMM2.0 at aa 12-34, 81-103, 116-133, 138-160, 167-189 and 194-213 272560020829 Signal peptide predicted for BPSS0928 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 26 and 27; signal peptide 272560020830 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 272560020831 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560020832 substrate binding pocket [chemical binding]; other site 272560020833 membrane-bound complex binding site; other site 272560020834 hinge residues; other site 272560020835 Helix-Turn-Helix DNA binding domain of putative transcription regulators from the MerR superfamily; Region: HTH_MerR-like_sg2; cd04778 272560020836 Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789 272560020837 DNA binding residues [nucleotide binding] 272560020838 putative dimer interface [polypeptide binding]; other site 272560020839 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560020840 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560020841 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560020842 Coenzyme A binding pocket [chemical binding]; other site 272560020843 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 57.8, E-value 1.6e-14 272560020844 6 probable transmembrane helices predicted for BPSS0931 by TMHMM2.0 at aa 24-43, 47-69, 81-98, 113-135, 137-154 and 174-196 272560020845 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560020846 D-galactonate transporter; Region: 2A0114; TIGR00893 272560020847 putative substrate translocation pore; other site 272560020848 13 probable transmembrane helices predicted for BPSS0932 by TMHMM2.0 at aa 24-46, 59-78, 88-107, 114-136, 151-170, 177-199, 214-236, 276-298, 313-335, 342-361, 371-393, 414-436 and 473-495 272560020849 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -82.5, E-value 6.2e-05 272560020850 methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048 272560020851 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181 272560020852 dimer interface [polypeptide binding]; other site 272560020853 ligand binding site [chemical binding]; other site 272560020854 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560020855 dimerization interface [polypeptide binding]; other site 272560020856 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560020857 dimer interface [polypeptide binding]; other site 272560020858 putative CheW interface [polypeptide binding]; other site 272560020859 2 probable transmembrane helices predicted for BPSS0933 by TMHMM2.0 at aa 20-42 and 199-221 272560020860 Pfam match to entry PF00672 HAMP, HAMP domain , score 40.6, E-value 2.3e-09 272560020861 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 361.2, E-value 7e-106 272560020862 PS00538 Bacterial chemotaxis sensory transducers signature. 272560020863 Nuclease-related domain; Region: NERD; pfam08378 272560020864 UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538 272560020865 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020866 BetR domain; Region: BetR; pfam08667 272560020867 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560020868 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560020869 active site 272560020870 phosphorylation site [posttranslational modification] 272560020871 intermolecular recognition site; other site 272560020872 dimerization interface [polypeptide binding]; other site 272560020873 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 272560020874 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560020875 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560020876 1 probable transmembrane helix predicted for BPSS0936 by TMHMM2.0 at aa 20-42 272560020877 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -85.6, E-value 0.0019 272560020878 Ion channel; Region: Ion_trans_2; pfam07885 272560020879 K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569 272560020880 TrkA-N domain; Region: TrkA_N; pfam02254 272560020881 3 probable transmembrane helices predicted for BPSS0937 by TMHMM2.0 at aa 42-61, 76-98 and 110-132 272560020882 Pfam match to entry PF02254 TrkA-N, TrkA-N domain , score 95.3, E-value 7.7e-26 272560020883 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560020884 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560020885 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 57.5, E-value 1.8e-14 272560020886 Carboxymuconolactone decarboxylase family; Region: CMD; cl00460 272560020887 Pfam match to entry PF02627 CMD, Carboxymuconolactone decarboxylase , score 104.6, E-value 1.2e-28 272560020888 Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423 272560020889 ornithine cyclodeaminase; Validated; Region: PRK07340 272560020890 Pfam match to entry PF02423 ODC_Mu_crystall, Ornithine cyclodeaminase/mu-crystallin family , score 23.9, E-value 3.7e-11 272560020891 Signal peptide predicted for BPSS0941 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 31 and 32; signal peptide 272560020892 Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187 272560020893 Putative esterase; Region: Esterase; pfam00756 272560020894 OpgC protein; Region: OpgC_C; pfam10129 272560020895 10 probable transmembrane helices predicted for BPSS0942 by TMHMM2.0 at aa 12-34, 49-66, 86-108, 139-161, 166-185, 200-222, 227-249, 264-286, 303-325 and 335-357 272560020896 Signal peptide predicted for BPSS0943 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 20 and 21; signal peptide 272560020897 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560020898 trimer interface [polypeptide binding]; other site 272560020899 eyelet of channel; other site 272560020900 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -45.4, E-value 0.00018 272560020901 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560020902 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020903 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421 272560020904 putative dimerization interface [polypeptide binding]; other site 272560020905 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 128.5, E-value 8e-36 272560020906 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 63.9, E-value 2.2e-16 272560020907 PS00044 Bacterial regulatory proteins, lysR family signature. 272560020908 Signal peptide predicted for BPSS0945 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.816 between residues 34 and 35; signal peptide 272560020909 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560020910 Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739 272560020911 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560020912 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560020913 Pfam match to entry PF01476 LysM, LysM domain , score 56.0, E-value 5.3e-14 272560020914 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 110.0, E-value 3e-30 272560020915 Signal peptide predicted for BPSS0945 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.816 between residues 21 and 22; signal peptide 272560020916 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191 272560020917 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560020918 Pfam match to entry PF00144 beta-lactamase, Beta-lactamase , score 410.0, E-value 1.4e-120 272560020919 PS00146 Beta-lactamase class-A active site. 272560020920 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560020921 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560020922 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560020923 substrate binding pocket [chemical binding]; other site 272560020924 dimerization interface [polypeptide binding]; other site 272560020925 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 99.0, E-value 6.3e-27 272560020926 Predicted helix-turn-helix motif with score 2117.000, SD 6.40 at aa 60-81, sequence RSFTRAADALCVTQGAISRQIQ 272560020927 PS00044 Bacterial regulatory proteins, lysR family signature. 272560020928 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 119.7, E-value 3.7e-33 272560020929 P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539 272560020930 Signal peptide predicted for BPSS0949 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 25 and 26; signal peptide 272560020931 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 272560020932 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560020933 Walker A/P-loop; other site 272560020934 ATP binding site [chemical binding]; other site 272560020935 Q-loop/lid; other site 272560020936 ABC transporter signature motif; other site 272560020937 Walker B; other site 272560020938 D-loop; other site 272560020939 H-loop/switch region; other site 272560020940 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 222.1, E-value 5.2e-64 272560020941 PS00211 ABC transporters family signature. 272560020942 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020943 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124 272560020944 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560020945 Walker A/P-loop; other site 272560020946 ATP binding site [chemical binding]; other site 272560020947 Q-loop/lid; other site 272560020948 ABC transporter signature motif; other site 272560020949 Walker B; other site 272560020950 D-loop; other site 272560020951 H-loop/switch region; other site 272560020952 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560020953 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 158.4, E-value 7.8e-45 272560020954 PS00017 ATP/GTP-binding site motif A (P-loop). 272560020955 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173 272560020956 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560020957 dimer interface [polypeptide binding]; other site 272560020958 conserved gate region; other site 272560020959 putative PBP binding loops; other site 272560020960 ABC-ATPase subunit interface; other site 272560020961 6 probable transmembrane helices predicted for BPSS0952 by TMHMM2.0 at aa 49-71, 117-139, 160-182, 217-234, 241-258 and 278-300 272560020962 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 31.1, E-value 1.7e-06 272560020963 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601 272560020964 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560020965 dimer interface [polypeptide binding]; other site 272560020966 conserved gate region; other site 272560020967 putative PBP binding loops; other site 272560020968 ABC-ATPase subunit interface; other site 272560020969 7 probable transmembrane helices predicted for BPSS0953 by TMHMM2.0 at aa 27-49, 121-143, 156-178, 221-240, 270-292, 297-319 and 326-348 272560020970 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 42.9, E-value 4.8e-10 272560020971 Signal peptide predicted for BPSS0954 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.776 between residues 19 and 20; signal peptide 272560020972 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 272560020973 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512 272560020974 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 76.8, E-value 3e-20 272560020975 D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178 272560020976 Pfam match to entry PF01427 Peptidase_M45, D-ala-D-ala dipeptidase , score 159.1, E-value 5e-45 272560020977 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560020978 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560020979 SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389 272560020980 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560020981 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560020982 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560020983 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 272560020984 Domain of unknown function (DUF1795); Region: DUF1795; pfam08786 272560020985 PAAR motif; Region: PAAR_motif; pfam05488 272560020986 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 272560020987 RHS Repeat; Region: RHS_repeat; pfam05593 272560020988 RHS Repeat; Region: RHS_repeat; pfam05593 272560020989 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560020990 RHS Repeat; Region: RHS_repeat; pfam05593 272560020991 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560020992 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 272560020993 RHS Repeat; Region: RHS_repeat; pfam05593 272560020994 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560020995 RHS Repeat; Region: RHS_repeat; pfam05593 272560020996 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560020997 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 272560020998 2 probable transmembrane helices predicted for BPSS0960 by TMHMM2.0 at aa 122-144 and 151-173 272560020999 Signal peptide predicted for BPSS0962 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.729 between residues 38 and 39; signal peptide 272560021000 Peptidase S8 family domain in Autotransporter serine proteases; Region: Peptidases_S8_Autotransporter_serine_protease_like; cd04848 272560021001 Subtilase family; Region: Peptidase_S8; pfam00082 272560021002 catalytic triad [active] 272560021003 putative active site [active] 272560021004 Autotransporter-associated beta strand repeat; Region: Autotrns_rpt; pfam12951 272560021005 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain [Function unknown]; Region: COG4625 272560021006 Autotransporter beta-domain; Region: Autotransporter; pfam03797 272560021007 Pfam match to entry PF00082 Peptidase_S8, Subtilase , score 33.3, E-value 1.3e-13 272560021008 PS00137 Serine proteases, subtilase, histidine active site. 272560021009 PS00138 Serine proteases, subtilase, serine active site. 272560021010 Pfam match to entry PF03797 Autotransporter Autotransporter beta-domain , score 148.5, E-value 7.8e-42 272560021011 2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy_3; pfam13640 272560021012 Signal peptide predicted for BPSS0964 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27; signal peptide 272560021013 The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512 272560021014 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 272560021015 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 58.1, E-value 1.2e-17 272560021016 Signal peptide predicted for BPSS0965 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.903 between residues 30 and 31; signal peptide 272560021017 bicupin, oxalate decarboxylase family; Region: bicupin_oxalic; TIGR03404 272560021018 Cupin; Region: Cupin_1; smart00835 272560021019 Thermophilic glucose-6-phosphate isomerase and related metalloenzymes [Carbohydrate transport and metabolism / General function prediction only]; Region: COG2140 272560021020 Pfam match to entry PF00190 Cupin, Cupin , score 71.7, E-value 1e-18 272560021021 Pfam match to entry PF00190 Cupin, Cupin , score 82.8, E-value 4.6e-22 272560021022 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; cl15845 272560021023 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 272560021024 10 probable transmembrane helices predicted for BPSS0966 by TMHMM2.0 at aa 32-51, 64-86, 141-163, 170-192, 212-234, 261-283, 303-325, 345-364, 369-391 and 408-430 272560021025 Pfam match to entry PF01566 Nramp, Natural resistance-associated macrophage protein , score 441.3, E-value 5.6e-130 272560021026 Predicted membrane protein [Function unknown]; Region: COG4682 272560021027 yiaA/B two helix domain; Region: YiaAB; pfam05360 272560021028 yiaA/B two helix domain; Region: YiaAB; pfam05360 272560021029 4 probable transmembrane helices predicted for BPSS0967 by TMHMM2.0 at aa 98-120, 130-147, 160-182 and 187-209 272560021030 Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; pfam01062 272560021031 3 probable transmembrane helices predicted for BPSS0968 by TMHMM2.0 at aa 13-35, 55-74 and 217-239 272560021032 oxidoreductase alpha (molybdopterin) subunit; Region: Fdhalpha-like; TIGR01701 272560021033 The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767 272560021034 putative molybdopterin cofactor binding site [chemical binding]; other site 272560021035 The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787 272560021036 putative molybdopterin cofactor binding site; other site 272560021037 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score -12.8, E-value 6.4e-15 272560021038 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560021039 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560021040 DNA-binding site [nucleotide binding]; DNA binding site 272560021041 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560021042 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560021043 homodimer interface [polypeptide binding]; other site 272560021044 catalytic residue [active] 272560021045 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 46.0, E-value 5.5e-11 272560021046 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 24.1, E-value 5.5e-08 272560021047 Predicted helix-turn-helix motif with score 1771.000, SD 5.22 at aa 53-74, sequence WSLAKLAKRAGMPMSALRRALT 272560021048 Signal peptide predicted for BPSS0972 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.827 between residues 21 and 22; signal peptide 272560021049 Putative MetA-pathway of phenol degradation; Region: Phenol_MetA_deg; pfam13557 272560021050 magnesium-transporting ATPase; Provisional; Region: PRK15122 272560021051 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 272560021052 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560021053 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 272560021054 haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710 272560021055 Soluble P-type ATPase [General function prediction only]; Region: COG4087 272560021056 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 272560021057 8 probable transmembrane helices predicted for BPSS0973 by TMHMM2.0 at aa 90-109, 119-136, 308-330, 340-362, 732-754, 799-821, 861-883 and 898-920 272560021058 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 72.3, E-value 6.8e-19 272560021059 PS00154 E1-E2 ATPases phosphorylation site. 272560021060 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 240.8, E-value 1.3e-69 272560021061 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus , score 61.2, E-value 1.4e-15 272560021062 Signal peptide predicted for BPSS0974 by SignalP 2.0 HMM (Signal peptide probability 0.890) with cleavage site probability 0.677 between residues 26 and 27; signal peptide 272560021063 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560021064 Peptidase S8 family domain, uncharacterized subfamily 13; Region: Peptidases_S8_13; cd07496 272560021065 Subtilase family; Region: Peptidase_S8; pfam00082 272560021066 active site 272560021067 catalytic triad [active] 272560021068 Pfam match to entry PF00082 Peptidase_S8, Subtilase , score 227.9, E-value 9.3e-66 272560021069 PS00138 Serine proteases, subtilase, serine active site. 272560021070 PS00137 Serine proteases, subtilase, histidine active site. 272560021071 Membrane bound FAD containing D-sorbitol dehydrogenase; Region: FAD-SLDH; pfam12318 272560021072 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 272560021073 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560021074 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560021075 Cytochrome c; Region: Cytochrom_C; pfam00034 272560021076 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560021077 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560021078 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 272560021079 PS00190 Cytochrome c family heme-binding site signature. 272560021080 PS00190 Cytochrome c family heme-binding site signature. 272560021081 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 20.5, E-value 0.00023 272560021082 PS00190 Cytochrome c family heme-binding site signature. 272560021083 Predicted membrane protein [Function unknown]; Region: COG2259 272560021084 4 probable transmembrane helices predicted for BPSS0978 by TMHMM2.0 at aa 12-34, 49-71, 78-100 and 115-134 272560021085 Signal peptide predicted for BPSS0979 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.599 between residues 20 and 21; signal peptide 272560021086 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560021087 trimer interface [polypeptide binding]; other site 272560021088 eyelet of channel; other site 272560021089 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -83.0, E-value 0.0056 272560021090 Protein of unknown function (DUF2837); Region: DUF2837; pfam10997 272560021091 5 probable transmembrane helices predicted for BPSS0980 by TMHMM2.0 at aa 5-27, 80-102, 157-179, 191-210 and 239-261 272560021092 ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215 272560021093 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560021094 dimer interface [polypeptide binding]; other site 272560021095 conserved gate region; other site 272560021096 putative PBP binding loops; other site 272560021097 ABC-ATPase subunit interface; other site 272560021098 5 probable transmembrane helices predicted for BPSS0981 by TMHMM2.0 at aa 20-42, 55-77, 92-109, 150-172 and 192-214 272560021099 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 45.5, E-value 7.8e-11 272560021100 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021101 ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160 272560021102 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560021103 dimer interface [polypeptide binding]; other site 272560021104 conserved gate region; other site 272560021105 putative PBP binding loops; other site 272560021106 ABC-ATPase subunit interface; other site 272560021107 3 probable transmembrane helices predicted for BPSS0982 by TMHMM2.0 at aa 20-42, 63-85 and 199-221 272560021108 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 24.5, E-value 0.00016 272560021109 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560021110 ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; Region: HisP; COG4598 272560021111 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560021112 Walker A/P-loop; other site 272560021113 ATP binding site [chemical binding]; other site 272560021114 Q-loop/lid; other site 272560021115 ABC transporter signature motif; other site 272560021116 Walker B; other site 272560021117 D-loop; other site 272560021118 H-loop/switch region; other site 272560021119 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 220.9, E-value 1.3e-63 272560021120 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021121 PS00211 ABC transporters family signature. 272560021122 This domain family includes the Enolpyruvate transferase (EPT) family and the RNA 3' phosphate cyclase family (RTPC). These 2 families differ in that EPT is formed by 3 repeats of an alpha-beta structural domain while RTPC has 3 similar repeats...; Region: EPT_RTPC-like; cl00288 272560021123 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275 272560021124 putative active site [active] 272560021125 Pfam match to entry PF00275 EPSP_syntase, EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) , score 104.9, E-value 1e-28 272560021126 Uncharacterized conserved protein [Function unknown]; Region: COG3791 272560021127 Signal peptide predicted for BPSS0986 by SignalP 2.0 HMM (Signal peptide probability 0.838) with cleavage site probability 0.838 between residues 24 and 25; signal peptide 272560021128 Signal peptide predicted for BPSS0987 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.918 between residues 17 and 18; signal peptide 272560021129 H+ Antiporter protein; Region: 2A0121; TIGR00900 272560021130 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021131 putative substrate translocation pore; other site 272560021132 8 probable transmembrane helices predicted for BPSS0988 by TMHMM2.0 at aa 21-43, 53-75, 88-110, 115-137, 225-247, 262-284, 289-311 and 316-335 272560021133 5 probable transmembrane helices predicted for BPSS0989 by TMHMM2.0 at aa 5-22, 34-56, 60-82, 103-125 and 135-157 272560021134 Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972 272560021135 Histidine kinase; Region: His_kinase; pfam06580 272560021136 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560021137 ATP binding site [chemical binding]; other site 272560021138 Mg2+ binding site [ion binding]; other site 272560021139 G-X-G motif; other site 272560021140 3 probable transmembrane helices predicted for BPSS0990 by TMHMM2.0 at aa 7-24, 29-51 and 99-121 272560021141 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 31.7, E-value 1.1e-06 272560021142 Similar to Pseudomonas aeruginosa positive alginate biosynthesis regulatory protein AlgR or pa5261 SWALL:ALGR_PSEAE (SWALL:P26275) (248 aa) fasta scores: E(): 7.6e-10, 35.24% id in 244 aa, and to Vibrio cholerae response regulator vca0850 SWALL:Q9KL96 (EMBL:AE004413) (261 aa) fasta scores: E(): 8.4e-18, 42.8% id in 257 aa. Contains a frameshift after codon 137;response regulator protein (pseudogene) 272560021143 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 85.7, E-value 6.3e-23 272560021144 Signal peptide predicted for BPSS0993 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 21 and 22; signal peptide 272560021145 Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753 272560021146 Clade 1 of the heme-binding enzyme catalase; Region: catalase_clade_1; cd08154 272560021147 tetramer interface [polypeptide binding]; other site 272560021148 heme binding pocket [chemical binding]; other site 272560021149 Pfam match to entry PF00199 catalase, Catalase , score 804.3, E-value 2.9e-239 272560021150 PS00438 Catalase proximal active site signature. 272560021151 PS00437 Catalase proximal heme-ligand signature. 272560021152 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021153 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560021154 S-adenosylmethionine binding site [chemical binding]; other site 272560021155 Predicted methyltransferase regulatory domain; Region: MethyTransf_Reg; pfam10119 272560021156 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560021157 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560021158 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 10.7, E-value 0.18 272560021159 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 39.8, E-value 4e-09 272560021160 Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 395-416, sequence LAIGEIAEVIGVTVRSLQNTFK 272560021161 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 272560021162 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 272560021163 [2Fe-2S] cluster binding site [ion binding]; other site 272560021164 START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643 272560021165 hydrophobic ligand binding site; other site 272560021166 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 74.6, E-value 1.3e-19 272560021167 Pfam match to entry PF00515 TPR, TPR Domain , score 12.8, E-value 0.12 272560021168 Pfam match to entry PF00515 TPR, TPR Domain , score 28.5, E-value 9.9e-06 272560021169 polyketide beta-ketoacyl:acyl carrier protein synthase; Validated; Region: PRK07103 272560021170 Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834 272560021171 dimer interface [polypeptide binding]; other site 272560021172 active site 272560021173 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 123.0, E-value 3.7e-34 272560021174 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 83.3, E-value 3.3e-22 272560021175 acyl carrier protein; Validated; Region: PRK07117 272560021176 polyketide biosynthesis enoyl-CoA hydratase; Validated; Region: PRK07110 272560021177 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560021178 substrate binding site [chemical binding]; other site 272560021179 oxyanion hole (OAH) forming residues; other site 272560021180 trimer interface [polypeptide binding]; other site 272560021181 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 187.5, E-value 1.4e-53 272560021182 PS00166 Enoyl-CoA hydratase/isomerase signature. 272560021183 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560021184 Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378 272560021185 substrate binding site [chemical binding]; other site 272560021186 oxyanion hole (OAH) forming residues; other site 272560021187 trimer interface [polypeptide binding]; other site 272560021188 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 174.0, E-value 1.6e-49 272560021189 PS00213 Lipocalin signature. 272560021190 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism]; Region: PksG; COG3425 272560021191 "initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827 272560021192 dimer interface [polypeptide binding]; other site 272560021193 active site 272560021194 Pfam match to entry PF01154 HMG_CoA_synt, Hydroxymethylglutaryl-coenzyme A synthase , score -102.2, E-value 6.7e-09 272560021195 Acyl transferase domain; Region: Acyl_transf_1; cl08282 272560021196 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 116.0, E-value 4.7e-32 272560021197 Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999 272560021198 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score -50.7, E-value 9.7e-05 272560021199 11 probable transmembrane helices predicted for BPSS1005 by TMHMM2.0 at aa 4-21, 28-50, 65-87, 100-122, 137-159, 172-194, 209-231, 259-278, 314-333, 346-368 and 378-400 272560021200 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021201 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021202 active site 272560021203 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560021204 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 272560021205 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028 272560021206 putative NADP binding site [chemical binding]; other site 272560021207 active site 272560021208 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560021209 Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090 272560021210 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560021211 Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212 272560021212 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560021213 catalytic residue [active] 272560021214 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021215 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021216 active site 272560021217 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021218 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021219 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021220 active site 272560021221 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 36.3, E-value 4.7e-08 272560021222 PS00012 Phosphopantetheine attachment site. 272560021223 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 362.3, E-value 3.4e-106 272560021224 PS00606 Beta-ketoacyl synthases active site. 272560021225 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 266.0, E-value 3.1e-77 272560021226 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 64.2, E-value 1.8e-16 272560021227 PS00012 Phosphopantetheine attachment site. 272560021228 Pfam match to entry PF01212 Beta_elim_lyase, Beta-eliminating lyase , score -143.8, E-value 4e-12 272560021229 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 280.9, E-value 1.1e-81 272560021230 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 226.4, E-value 2.7e-65 272560021231 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 368.5, E-value 4.6e-108 272560021232 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 295.5, E-value 4.1e-86 272560021233 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021234 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021235 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021236 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021237 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021238 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021239 active site 272560021240 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560021241 active site 2 [active] 272560021242 active site 1 [active] 272560021243 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 272560021244 putative NADP binding site [chemical binding]; other site 272560021245 short chain dehydrogenase; Region: adh_short; pfam00106 272560021246 active site 272560021247 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021248 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021249 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021250 active site 272560021251 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021252 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021253 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021254 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021255 active site 272560021256 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560021257 NAD(P) binding site [chemical binding]; other site 272560021258 active site 272560021259 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021260 S-adenosylmethionine binding site [chemical binding]; other site 272560021261 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021262 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021263 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021264 active site 272560021265 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560021266 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 35.6, E-value 7.4e-08 272560021267 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 52.3, E-value 6.9e-13 272560021268 PS00012 Phosphopantetheine attachment site. 272560021269 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 57.9, E-value 1.4e-14 272560021270 PS00012 Phosphopantetheine attachment site. 272560021271 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 16.5, E-value 0.00041 272560021272 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 405.4, E-value 3.6e-119 272560021273 PS00606 Beta-ketoacyl synthases active site. 272560021274 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 279.1, E-value 3.7e-81 272560021275 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021276 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 4.8, E-value 9.1e-08 272560021277 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 33.5, E-value 3.2e-07 272560021278 PS00012 Phosphopantetheine attachment site. 272560021279 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 352.6, E-value 2.7e-103 272560021280 PS00037 Myb DNA-binding domain repeat signature 1. 272560021281 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 253.4, E-value 2e-73 272560021282 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 62.5, E-value 5.8e-16 272560021283 PS00012 Phosphopantetheine attachment site. 272560021284 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 58.5, E-value 9.5e-15 272560021285 PS00012 Phosphopantetheine attachment site. 272560021286 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 402.7, E-value 2.3e-118 272560021287 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 298.1, E-value 7e-87 272560021288 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560021289 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560021290 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 56.1, E-value 5e-14 272560021291 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 249.1, E-value 4e-72 272560021292 PS00606 Beta-ketoacyl synthases active site. 272560021293 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 215.6, E-value 4.9e-62 272560021294 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 55.1, E-value 1e-13 272560021295 Condensation domain; Region: Condensation; cl19241 272560021296 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560021297 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560021298 The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116 272560021299 acyl-activating enzyme (AAE) consensus motif; other site 272560021300 AMP binding site [chemical binding]; other site 272560021301 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021302 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 272560021303 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021304 active site 272560021305 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560021306 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560021307 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021308 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021309 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021310 active site 272560021311 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560021312 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 272560021313 putative NADP binding site [chemical binding]; other site 272560021314 short chain dehydrogenase; Region: adh_short; pfam00106 272560021315 active site 272560021316 Methyltransferase domain; Region: Methyltransf_12; pfam08242 272560021317 Methyltransferase domain; Region: Methyltransf_23; pfam13489 272560021318 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021319 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021320 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021321 Pfam match to entry PF00668 Condensation, Condensation domain , score 118.6, E-value 7.7e-33 272560021322 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 485.6, E-value 2.5e-143 272560021323 PS00455 AMP-binding domain signature. 272560021324 PS00215 Mitochondrial energy transfer proteins signature. 272560021325 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 57.9, E-value 1.5e-14 272560021326 PS00012 Phosphopantetheine attachment site. 272560021327 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 239.6, E-value 2.8e-69 272560021328 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 286.4, E-value 2.3e-83 272560021329 Predicted helix-turn-helix motif with score 1028.000, SD 2.69 at aa 1456-1477, sequence DVIRKVLDATGIHPETIGYVEA 272560021330 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 48.0, E-value 1.4e-11 272560021331 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 370.2, E-value 1.4e-108 272560021332 PS00606 Beta-ketoacyl synthases active site. 272560021333 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 291.3, E-value 7.7e-85 272560021334 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 80.0, E-value 3.1e-21 272560021335 PS00012 Phosphopantetheine attachment site. 272560021336 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 80.0, E-value 3.1e-21 272560021337 PS00012 Phosphopantetheine attachment site. 272560021338 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 80.0, E-value 3.1e-21 272560021339 PS00012 Phosphopantetheine attachment site. 272560021340 Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090 272560021341 Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212 272560021342 Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945 272560021343 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560021344 catalytic residue [active] 272560021345 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021346 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021347 active site 272560021348 Pfam match to entry PF01212 Beta_elim_lyase, Beta-eliminating lyase , score -198.4, E-value 2.1e-09 272560021349 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 323.3, E-value 1.8e-94 272560021350 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 160.2, E-value 2.2e-45 272560021351 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560021352 Signal peptide predicted for BPSS1011 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.903 between residues 39 and 40; signal peptide 272560021353 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021354 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560021355 putative substrate translocation pore; other site 272560021356 14 probable transmembrane helices predicted for BPSS1011 by TMHMM2.0 at aa 13-35, 48-67, 79-101, 111-133, 140-162, 166-188, 200-222, 227-249, 269-291, 306-328, 330-352, 367-389, 396-418 and 438-460 272560021357 Signal peptide predicted for BPSS1012 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.917 between residues 37 and 38; signal peptide 272560021358 putative voltage-gated ClC-type chloride channel ClcB; Provisional; Region: PRK01862 272560021359 CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400 272560021360 Cl- selectivity filter; other site 272560021361 Cl- binding residues [ion binding]; other site 272560021362 pore gating glutamate residue; other site 272560021363 dimer interface [polypeptide binding]; other site 272560021364 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with either the SpoIVFB domain (sporulation protein, stage IV cell wall formation, F locus, promoter-distal B) or the chloride channel protein EriC; Region: CBS_pair_SpoIVFB_EriC_assoc; cd04612 272560021365 Pfam match to entry PF00571 CBS, CBS domain , score 24.4, E-value 0.00017 272560021366 Pfam match to entry PF00571 CBS, CBS domain , score 19.9, E-value 0.004 272560021367 Pfam match to entry PF00654 voltage_CLC, Voltage gated chloride channel , score 55.0, E-value 2.6e-15 272560021368 11 probable transmembrane helices predicted for BPSS1012 by TMHMM2.0 at aa 20-42, 62-84, 132-154, 164-186, 199-218, 233-255, 267-289, 304-326, 333-355, 365-387 and 394-413 272560021369 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560021370 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560021371 CBS-domain-containing membrane protein [Signal transduction mechanisms]; Region: COG3448 272560021372 HPP family; Region: HPP; pfam04982 272560021373 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the HPP motif domain. These proteins are integral membrane proteins with four transmembrane spanning helices. The function of these proteins is...; Region: CBS_pair_HPP_assoc; cd04600 272560021374 Pfam match to entry PF00571 CBS, CBS domain , score 57.9, E-value 1.5e-14 272560021375 Pfam match to entry PF00571 CBS, CBS domain , score 65.4, E-value 8.1e-17 272560021376 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560021377 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560021378 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560021379 putative effector binding pocket; other site 272560021380 dimerization interface [polypeptide binding]; other site 272560021381 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 59.1, E-value 6.1e-15 272560021382 Predicted helix-turn-helix motif with score 1215.000, SD 3.33 at aa 51-72, sequence GSFTAVAKEIDATTAQVSRAVS 272560021383 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 144.5, E-value 1.2e-40 272560021384 calcium/sodium:proton antiporter; Provisional; Region: PRK10599 272560021385 Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699 272560021386 10 probable transmembrane helices predicted for BPSS1016 by TMHMM2.0 at aa 48-70, 83-105, 120-142, 155-177, 187-204, 233-255, 270-292, 305-327, 331-353 and 360-379 272560021387 Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095 272560021388 Pfam match to entry PF01914 MarC, MarC family integral membrane protein , score 119.4, E-value 4.3e-33 272560021389 5 probable transmembrane helices predicted for BPSS1017 by TMHMM2.0 at aa 48-70, 90-112, 158-180, 187-209 and 229-251 272560021390 Signal peptide predicted for BPSS1018 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.696 between residues 33 and 34; signal peptide 272560021391 CAAX protease self-immunity; Region: Abi; pfam02517 272560021392 9 probable transmembrane helices predicted for BPSS1018 by TMHMM2.0 at aa 7-37, 52-74, 86-108, 128-150, 163-185, 195-217, 224-246, 251-270 and 277-299 272560021393 Pfam match to entry PF02517 Abi, CAAX amino terminal protease , score 34.8, E-value 1.3e-07 272560021394 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 272560021395 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 272560021396 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 204.9, E-value 8.2e-59 272560021397 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560021398 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560021399 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 56.1, E-value 5.1e-14 272560021400 PS00041 Bacterial regulatory proteins, araC family signature. 272560021401 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 25.0, E-value 0.00012 272560021402 Predicted helix-turn-helix motif with score 1363.000, SD 3.83 at aa 213-234, sequence LTLAGTARAACLSPNYLAHLIR 272560021403 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560021404 RNA polymerase sigma factor; Provisional; Region: PRK12547 272560021405 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560021406 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560021407 DNA binding residues [nucleotide binding] 272560021408 Predicted helix-turn-helix motif with score 973.000, SD 2.50 at aa 124-145, sequence LSYQDASAVLGVPVGTVMSRLS 272560021409 Predicted transmembrane transcriptional regulator (anti-sigma factor) [Transcription]; Region: COG5662 272560021410 Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872 272560021411 Signal peptide predicted for BPSS1024 by SignalP 2.0 HMM (Signal peptide probability 0.719) with cleavage site probability 0.214 between residues 22 and 23; signal peptide 272560021412 YceI-like domain; Region: YceI; pfam04264 272560021413 Signal peptide predicted for BPSS1025 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 19 and 20; signal peptide 272560021414 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 272560021415 Secreted repeat of unknown function; Region: Lipoprotein_15; pfam03640 272560021416 Pfam match to entry PF03640 Lipoprotein_15, Secreted repeat of unknown function , score 49.3, E-value 5.6e-12 272560021417 Pfam match to entry PF03640 Lipoprotein_15, Secreted repeat of unknown function , score 42.5, E-value 6.2e-10 272560021418 RNA polymerase sigma factor; Provisional; Region: PRK12528 272560021419 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560021420 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 272560021421 DNA binding residues [nucleotide binding] 272560021422 Predicted helix-turn-helix motif with score 1331.000, SD 3.72 at aa 136-157, sequence MTHAQIAAELRVSLATVKRYLV 272560021423 Fe2+-dicitrate sensor, membrane component [Inorganic ion transport and metabolism / Signal transduction mechanisms]; Region: FecR; COG3712 272560021424 FecR protein; Region: FecR; pfam04773 272560021425 Signal peptide predicted for BPSS1029 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.919 between residues 39 and 40; signal peptide 272560021426 Secretin and TonB N terminus short domain; Region: STN; smart00965 272560021427 TonB-dependent siderophore receptor; Region: TonB-siderophor; TIGR01783 272560021428 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560021429 N-terminal plug; other site 272560021430 ligand-binding site [chemical binding]; other site 272560021431 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 49.8, E-value 3.9e-12 272560021432 Signal peptide predicted for BPSS1030 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.810 between residues 27 and 28; signal peptide 272560021433 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560021434 TM-ABC transporter signature motif; other site 272560021435 9 probable transmembrane helices predicted for BPSS1030 by TMHMM2.0 at aa 10-32, 45-67, 82-104, 109-131, 161-183, 210-232, 242-261, 268-290 and 294-313 272560021436 Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism]; Region: AraH; COG1172 272560021437 TM-ABC transporter signature motif; other site 272560021438 9 probable transmembrane helices predicted for BPSS1031 by TMHMM2.0 at aa 53-75, 82-99, 109-126, 133-155, 201-220, 253-275, 280-297, 302-324 and 328-350 272560021439 Signal peptide predicted for BPSS1032 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.456 between residues 19 and 20; signal peptide 272560021440 ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129 272560021441 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560021442 Walker A/P-loop; other site 272560021443 ATP binding site [chemical binding]; other site 272560021444 Q-loop/lid; other site 272560021445 ABC transporter signature motif; other site 272560021446 Walker B; other site 272560021447 D-loop; other site 272560021448 H-loop/switch region; other site 272560021449 Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215 272560021450 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 79.5, E-value 4.4e-21 272560021451 PS00211 ABC transporters family signature. 272560021452 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 146.2, E-value 3.9e-41 272560021453 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021454 Signal peptide predicted for BPSS1033 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.705 between residues 35 and 36; signal peptide 272560021455 Methylthioribose-binding protein-like of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_methylthioribose_binding_like; cd06305 272560021456 Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407 272560021457 putative ligand binding site [chemical binding]; other site 272560021458 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score -25.1, E-value 0.0006 272560021459 Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020 272560021460 3 probable transmembrane helices predicted for BPSS1034 by TMHMM2.0 at aa 44-66, 76-98 and 111-128 272560021461 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560021462 sulfur acquisition oxidoreductase, SfnB family; Region: sulfur_SfnB; TIGR04022 272560021463 active site 272560021464 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021465 Sugar (and other) transporter; Region: Sugar_tr; pfam00083 272560021466 putative substrate translocation pore; other site 272560021467 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 67.3, E-value 2.2e-17 272560021468 12 probable transmembrane helices predicted for BPSS1037 by TMHMM2.0 at aa 36-58, 73-95, 108-130, 134-153, 165-187, 197-216, 280-302, 312-334, 346-365, 369-391, 412-434 and 439-461 272560021469 PS00217 Sugar transport proteins signature 2. 272560021470 Signal peptide predicted for BPSS1038 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 26 and 27; signal peptide 272560021471 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560021472 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021473 Signal peptide predicted for BPSS1039 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.588 between residues 29 and 30; signal peptide 272560021474 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 272560021475 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560021476 dimerization interface [polypeptide binding]; other site 272560021477 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560021478 dimer interface [polypeptide binding]; other site 272560021479 phosphorylation site [posttranslational modification] 272560021480 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560021481 ATP binding site [chemical binding]; other site 272560021482 Mg2+ binding site [ion binding]; other site 272560021483 G-X-G motif; other site 272560021484 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 149.8, E-value 3e-42 272560021485 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 69.6, E-value 4.3e-18 272560021486 Pfam match to entry PF00672 HAMP, HAMP domain , score 53.4, E-value 3.3e-13 272560021487 2 probable transmembrane helices predicted for BPSS1039 by TMHMM2.0 at aa 15-37 and 165-187 272560021488 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 272560021489 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560021490 active site 272560021491 phosphorylation site [posttranslational modification] 272560021492 intermolecular recognition site; other site 272560021493 dimerization interface [polypeptide binding]; other site 272560021494 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560021495 DNA binding site [nucleotide binding] 272560021496 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 99.3, E-value 5e-27 272560021497 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 138.9, E-value 6.1e-39 272560021498 heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914 272560021499 Signal peptide predicted for BPSS1041 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.914 between residues 30 and 31; signal peptide 272560021500 MMPL family; Region: MMPL; cl14618 272560021501 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1554.3, E-value 0 272560021502 11 probable transmembrane helices predicted for BPSS1041 by TMHMM2.0 at aa 10-29, 353-375, 395-414, 451-470, 485-507, 532-554, 890-907, 914-936, 940-962, 986-1008 and 1018-1040 272560021503 Signal peptide predicted for BPSS1042 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.740 between residues 41 and 42; signal peptide 272560021504 Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404 272560021505 Membrane Fusion Protein cluster 2 (function with RND porters); Region: 8a0102; TIGR00999 272560021506 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560021507 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 56.0, E-value 5.4e-14 272560021508 1 probable transmembrane helix predicted for BPSS1042 by TMHMM2.0 at aa 5-24 272560021509 Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538 272560021510 Outer membrane efflux protein; Region: OEP; pfam02321 272560021511 Outer membrane efflux protein; Region: OEP; pfam02321 272560021512 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 89.7, E-value 3.7e-24 272560021513 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 86.2, E-value 4.3e-23 272560021514 PS00215 Mitochondrial energy transfer proteins signature. 272560021515 Adenosine specific kinase; Region: Adenosine_kin; pfam04008 272560021516 Pfam match to entry PF04008 DUF355, Protein of unknown function (DUF355) , score 322.9, E-value 2.3e-94 272560021517 YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cd04332 272560021518 putative deacylase active site [active] 272560021519 Genomic island GI 15; prophage or prophage remnant 272560021520 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560021521 sequence-specific DNA binding site [nucleotide binding]; other site 272560021522 salt bridge; other site 272560021523 Phage related protein; Region: DUF3693; pfam12472 272560021524 Predicted helix-turn-helix motif with score 1301.000, SD 3.62 at aa 8-29, sequence PSDYAAAKVLGVTRGAVSKYRN 272560021525 Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cl19095 272560021526 PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 272560021527 Bacteriophage replication gene A protein (GPA); Region: Phage_GPA; pfam05840 272560021528 Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606 272560021529 Ogr/Delta-like zinc finger; Region: Ogr_Delta; pfam04606 272560021530 ParA-like protein; Provisional; Region: PHA02518 272560021531 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 272560021532 P-loop; other site 272560021533 Magnesium ion binding site [ion binding]; other site 272560021534 Pfam match to entry PF00991 ParA, ParA family ATPase , score 8.1, E-value 0.00034 272560021535 Pfam match to entry PF01402 HTH_4, Ribbon-helix-helix protein, copG family , score 19.5, E-value 3.7e-05 272560021536 PAAR motif; Region: PAAR_motif; pfam05488 272560021537 Uncharacterized protein conserved in bacteria (DUF2345); Region: DUF2345; cl01733 272560021538 VRR-NUC domain; Region: VRR_NUC; pfam08774 272560021539 Protein of unknown function (DUF3396); Region: DUF3396; pfam11876 272560021540 Region with similarity to part of (BPSL0144 to BPSL1175) Genomic island GI 2 (phiK96243) 272560021541 putative addiction module killer protein; Region: upstrm_HI1419; TIGR02683 272560021542 Predicted transcriptional regulator [Transcription]; Region: COG3636; cl17681 272560021543 Predicted helix-turn-helix motif with score 1567.000, SD 4.52 at aa 50-71, sequence RGMTALARESGVKREALYRALS 272560021544 portal vertex protein; Provisional; Region: Q; PHA02536 272560021545 terminase ATPase subunit; Provisional; Region: P; PHA02535 272560021546 Putative ATPase subunit of terminase (gpP-like); Region: Terminase_5; pfam06056 272560021547 Phage Terminase; Region: Terminase_1; cl19862 272560021548 Predicted helix-turn-helix motif with score 1584.000, SD 4.58 at aa 38-59, sequence WRIASIARHLDIKPATVASWCR 272560021549 capsid-scaffolding protein; Provisional; Region: O; PHA02529 272560021550 capsid protein; Provisional; Region: N; PHA02538 272560021551 Signal peptide predicted for BPSS1066 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.448 between residues 29 and 30; signal peptide 272560021552 terminase endonuclease subunit; Provisional; Region: M; PHA02537 272560021553 Signal peptide predicted for BPSS1067 by SignalP 2.0 HMM (Signal peptide probability 0.676) with cleavage site probability 0.518 between residues 13 and 14; signal peptide 272560021554 Phage head completion protein (GPL); Region: Phage_GPL; pfam05926 272560021555 hypothetical protein; Region: PHA02417 272560021556 Phage Tail Protein X; Region: Phage_tail_X; pfam05489 272560021557 Signal peptide predicted for BPSS1070 by SignalP 2.0 HMM (Signal peptide probability 0.964) with cleavage site probability 0.544 between residues 24 and 25; signal peptide 272560021558 3 probable transmembrane helices predicted for BPSS1070 by TMHMM2.0 at aa 20-42, 54-76 and 81-98 272560021559 Protein of unknown function (DUF754); Region: DUF754; pfam05449 272560021560 3 probable transmembrane helices predicted for BPSS1071 by TMHMM2.0 at aa 4-23, 32-54 and 59-76 272560021561 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 272560021562 Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409 272560021563 Protein of unknown function (DUF3380); Region: DUF3380; pfam11860 272560021564 Pfam match to entry PF01471 PG_binding_1, peptidoglycan binding domain , score 46.2, E-value 4.7e-11 272560021565 phage lysis regulatory protein, LysB family; Region: phage_LysB; TIGR03495 272560021566 Signal peptide predicted for BPSS1073 by SignalP 2.0 HMM (Signal peptide probability 0.987) with cleavage site probability 0.660 between residues 23 and 24; signal peptide 272560021567 P2 phage tail completion protein R (GpR); Region: P2_Phage_GpR; pfam06891 272560021568 Signal peptide predicted for BPSS1074 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.798 between residues 20 and 21; signal peptide 272560021569 Phage virion morphogenesis family; Region: Phage_tail_S; pfam05069 272560021570 hypothetical protein; Region: PHA02416 272560021571 DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863 272560021572 Pfam match to entry PF01555 N6_N4_Mtase, DNA methylase , score 48.5, E-value 9.3e-12 272560021573 PS00092 N-6 Adenine-specific DNA methylases signature. 272560021574 Phage P2 baseplate assembly protein gpV [General function prediction only]; Region: gpV; COG4540 272560021575 baseplate wedge subunit; Provisional; Region: W; PHA02516 272560021576 baseplate assembly protein; Provisional; Region: J; PHA02568 272560021577 PS00041 Bacterial regulatory proteins, araC family signature. 272560021578 Phage tail protein (Tail_P2_I); Region: Tail_P2_I; pfam09684 272560021579 Phage Tail Collar Domain; Region: Collar; pfam07484 272560021580 Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413 272560021581 major tail sheath protein; Provisional; Region: FI; PHA02560 272560021582 major tail tube protein; Provisional; Region: FII; PHA02600 272560021583 Mu-like prophage FluMu protein gp41; Region: FluMu_gp41; pfam10109 272560021584 Phage P2 GpE; Region: Phage_P2_GpE; pfam06528 272560021585 Phage-related tail protein [Function unknown]; Region: COG5283 272560021586 Bacterial protein of unknown function (DUF883); Region: DUF883; cl01888 272560021587 6 probable transmembrane helices predicted for BPSS1087 by TMHMM2.0 at aa 576-598, 605-627, 637-659, 666-688, 751-773 and 780-802 272560021588 Phage P2 GpU; Region: Phage_P2_GpU; pfam06995 272560021589 tail protein; Provisional; Region: D; PHA02561 272560021590 Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686 272560021591 Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305 272560021592 hexamer interface [polypeptide binding]; other site 272560021593 ligand binding site [chemical binding]; other site 272560021594 putative active site [active] 272560021595 NAD(P) binding site [chemical binding]; other site 272560021596 Pfam match to entry PF01262 AlaDh_PNT, Alanine dehydrogenase/pyridine nucleotide transhydrogenase , score 509.1, E-value 2.1e-150 272560021597 H-NS histone family; Region: Histone_HNS; pfam00816 272560021598 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560021599 putative kissing complex interaction region; other site 272560021600 putative RNA binding sites [nucleotide binding]; other site 272560021601 ProQ/FINO family; Region: ProQ; pfam04352 272560021602 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421 272560021603 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560021604 Domain of unknown function (DUF2760); Region: DUF2760; pfam10816 272560021605 PS00449 ATP synthase a subunit signature. 272560021606 Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443 272560021607 Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170 272560021608 nucleotide binding site [chemical binding]; other site 272560021609 putative NEF/HSP70 interaction site [polypeptide binding]; other site 272560021610 SBD interface [polypeptide binding]; other site 272560021611 PS00297 Heat shock hsp70 proteins family signature 1. 272560021612 PS00329 Heat shock hsp70 proteins family signature 2. 272560021613 Nucleotide-binding domain of the HSP70 family; Region: HSP70_NBD; cd10170 272560021614 nucleotide binding site [chemical binding]; other site 272560021615 putative NEF/HSP70 interaction site [polypeptide binding]; other site 272560021616 SBD interface [polypeptide binding]; other site 272560021617 DNA-K related protein; Region: DUF3731; pfam12531 272560021618 CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381 272560021619 putative active site [active] 272560021620 putative metal binding site [ion binding]; other site 272560021621 Signal peptide predicted for BPSS1099 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.745 between residues 21 and 22; signal peptide 272560021622 5 probable transmembrane helices predicted for BPSS1099 by TMHMM2.0 at aa 5-27, 42-59, 94-116, 121-143 and 156-178 272560021623 Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474 272560021624 Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690 272560021625 E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122 272560021626 Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246 272560021627 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560021628 motif II; other site 272560021629 Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689 272560021630 8 probable transmembrane helices predicted for BPSS1100 by TMHMM2.0 at aa 65-84, 89-106, 249-268, 283-305, 663-685, 736-758, 771-793 and 813-835 272560021631 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 100.6, E-value 2.1e-27 272560021632 PS00154 E1-E2 ATPases phosphorylation site. 272560021633 Pfam match to entry PF00122 E1-E2_ATPase, E1-E2 ATPase , score 188.5, E-value 7e-54 272560021634 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021635 Pfam match to entry PF00690 Cation_ATPase_N, Cation transporter/ATPase, N-terminus , score 22.7, E-value 3.3e-06 272560021636 Signal peptide predicted for BPSS1101 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.775 between residues 27 and 28; signal peptide 272560021637 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560021638 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021639 S-adenosylmethionine binding site [chemical binding]; other site 272560021640 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560021641 Signal peptide predicted for BPSS1103 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23; signal peptide 272560021642 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 272560021643 Mannan-binding protein; Region: MVL; pfam12151 272560021644 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 3.3, E-value 3.7e-05 272560021645 4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169 272560021646 dimer interface [polypeptide binding]; other site 272560021647 substrate binding site [chemical binding]; other site 272560021648 ATP binding site [chemical binding]; other site 272560021649 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 16.5, E-value 4.7e-05 272560021650 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021651 S-adenosylmethionine binding site [chemical binding]; other site 272560021652 Pfam match to entry PF01209 Ubie_methyltran, ubiE/COQ5 methyltransferase , score -108.2, E-value 3e-05 272560021653 Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351 272560021654 dimerization interface [polypeptide binding]; other site 272560021655 active site 272560021656 Nucleoside 2-deoxyribosyltransferase; Region: Nuc_deoxyrib_tr; cl17818 272560021657 Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673 272560021658 nudix motif; other site 272560021659 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 88.6, E-value 8.4e-24 272560021660 PS00893 mutT domain signature. 272560021661 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560021662 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021663 S-adenosylmethionine binding site [chemical binding]; other site 272560021664 Protein of unknown function (DUF971); Region: DUF971; cl01414 272560021665 gamma-butyrobetaine hydroxylase; Region: carnitine_bodg; TIGR02409 272560021666 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560021667 substrate binding pocket [chemical binding]; other site 272560021668 active site 272560021669 iron coordination sites [ion binding]; other site 272560021670 Pfam match to entry PF03322 Gamma-BBH, Gamma-butyrobetaine hydroxylase , score 93.0, E-value 4e-25 272560021671 PS00215 Mitochondrial energy transfer proteins signature. 272560021672 Signal peptide predicted for BPSS1111 by SignalP 2.0 HMM (Signal peptide probability 0.977) with cleavage site probability 0.394 between residues 17 and 18; signal peptide 272560021673 phosphonate utilization associated putative membrane protein; Region: phn_DUF6; TIGR03340 272560021674 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 42.6, E-value 5.9e-10 272560021675 7 probable transmembrane helices predicted for BPSS1111 by TMHMM2.0 at aa 4-23, 30-52, 57-79, 91-108, 112-134, 141-163 and 173-192 272560021676 arginine-ornithine antiporter; Region: arg_ornith_anti; TIGR03810 272560021677 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560021678 13 probable transmembrane helices predicted for BPSS1112 by TMHMM2.0 at aa 31-50, 60-82, 118-140, 150-167, 174-196, 224-243, 256-278, 303-325, 346-368, 378-400, 413-435, 440-457 and 469-491 272560021679 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -237.3, E-value 0.00065 272560021680 Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705 272560021681 6 probable transmembrane helices predicted for BPSS1113 by TMHMM2.0 at aa 20-42, 79-101, 114-133, 137-159, 166-188 and 198-220 272560021682 Pfam match to entry PF01694 Rhomboid, Rhomboid family , score 126.3, E-value 3.7e-35 272560021683 Signal peptide predicted for BPSS1114 by SignalP 2.0 HMM (Signal peptide probability 0.956) with cleavage site probability 0.713 between residues 28 and 29; signal peptide 272560021684 ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241 272560021685 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560021686 Walker A motif; other site 272560021687 ATP binding site [chemical binding]; other site 272560021688 Walker B motif; other site 272560021689 arginine finger; other site 272560021690 Peptidase family M41; Region: Peptidase_M41; pfam01434 272560021691 Pfam match to entry PF01434 Peptidase_M41, Peptidase M41 , score 329.8, E-value 2.1e-96 272560021692 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 317.3, E-value 1.2e-92 272560021693 PS00674 AAA-protein family signature. 272560021694 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021695 2 probable transmembrane helices predicted for BPSS1114 by TMHMM2.0 at aa 5-27 and 117-139 272560021696 N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653 272560021697 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560021698 active site 272560021699 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560021700 putative DNA binding site [nucleotide binding]; other site 272560021701 Predicted transcriptional regulator [Transcription]; Region: COG2345 272560021702 putative Zn2+ binding site [ion binding]; other site 272560021703 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560021704 Transcriptional regulator PadR-like family; Region: PadR; cl17335 272560021705 Protein of unknown function (DUF2505); Region: DUF2505; pfam10698 272560021706 Signal peptide predicted for BPSS1118 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.498 between residues 29 and 30; signal peptide 272560021707 RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730 272560021708 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560021709 Plasmid protein of unknown function (Plasmid_RAQPRD); Region: Plasmid_RAQPRD; cl19622 272560021710 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560021711 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 44.4, E-value 1.7e-10 272560021712 Signal peptide predicted for BPSS1119 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.668 between residues 31 and 32; signal peptide 272560021713 multidrug efflux protein; Reviewed; Region: PRK09579 272560021714 MMPL family; Region: MMPL; cl14618 272560021715 MMPL family; Region: MMPL; cl14618 272560021716 Pfam match to entry PF00873 ACR_tran, AcrB/AcrD/AcrF family , score 1023.3, E-value 0 272560021717 12 probable transmembrane helices predicted for BPSS1119 by TMHMM2.0 at aa 7-29, 327-349, 354-376, 381-403, 427-449, 464-486, 517-539, 842-861, 868-890, 895-917, 938-960 and 970-992 272560021718 copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837 272560021719 Outer membrane efflux protein; Region: OEP; pfam02321 272560021720 Outer membrane efflux protein; Region: OEP; pfam02321 272560021721 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560021722 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 175.2, E-value 7e-50 272560021723 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 184.1, E-value 1.4e-52 272560021724 GTP cyclohydrolase II (RibA). GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641 272560021725 dimerization interface [polypeptide binding]; other site 272560021726 active site 272560021727 Pfam match to entry PF00925 GTP_cyclohydro2, GTP cyclohydrolase II , score 234.7, E-value 8.4e-68 272560021728 FOG: WD40 repeat [General function prediction only]; Region: COG2319 272560021729 WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200 272560021730 structural tetrad; other site 272560021731 WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200 272560021732 structural tetrad; other site 272560021733 FOG: WD40 repeat [General function prediction only]; Region: COG2319 272560021734 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 7.3, E-value 1.3 272560021735 PS00678 Trp-Asp (WD) repeats signature. 272560021736 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 15.6, E-value 0.075 272560021737 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 29.3, E-value 6e-06 272560021738 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 36.8, E-value 3.2e-08 272560021739 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 17.7, E-value 0.018 272560021740 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 20.7, E-value 0.0023 272560021741 Pfam match to entry PF00400 WD40, WD domain, G-beta repeat , score 25.7, E-value 7.3e-05 272560021742 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021743 S-adenosylmethionine binding site [chemical binding]; other site 272560021744 Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582 272560021745 Uncharacterized conserved protein [Function unknown]; Region: COG1262 272560021746 Pfam match to entry PF03781 DUF323, Domain of unknown function (DUF323) , score 141.2, E-value 1.2e-39 272560021747 riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326 272560021748 Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284 272560021749 catalytic motif [active] 272560021750 Zn binding site [ion binding]; other site 272560021751 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region , score 133.4, E-value 2.6e-37 272560021752 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 272560021753 O-methyltransferase; Region: Methyltransf_2; pfam00891 272560021754 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021755 S-adenosylmethionine binding site [chemical binding]; other site 272560021756 Pfam match to entry PF00891 Methyltransf_2, O-methyltransferase , score 19.0, E-value 7.2e-11 272560021757 This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632 272560021758 active site 272560021759 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 36.3, E-value 4.4e-08 272560021760 Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814 272560021761 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021762 putative substrate translocation pore; other site 272560021763 14 probable transmembrane helices predicted for BPSS1128 by TMHMM2.0 at aa 21-40, 55-77, 84-103, 113-135, 147-169, 173-195, 207-224, 229-248, 268-290, 300-322, 334-353, 358-380, 401-423 and 438-460 272560021764 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 15.1, E-value 8.6e-05 272560021765 Predicted small integral membrane protein (DUF2165); Region: DUF2165; cl02290 272560021766 4 probable transmembrane helices predicted for BPSS1129 by TMHMM2.0 at aa 15-37, 73-95, 115-137 and 144-163 272560021767 PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 272560021768 PAS fold; Region: PAS_4; pfam08448 272560021769 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560021770 DNA binding residues [nucleotide binding] 272560021771 dimerization interface [polypeptide binding]; other site 272560021772 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 50.8, E-value 1.9e-12 272560021773 Predicted helix-turn-helix motif with score 1474.000, SD 4.21 at aa 182-203, sequence KTAKDIANILGLSARTIEQYME 272560021774 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560021775 1 probable transmembrane helix predicted for BPSS1132 by TMHMM2.0 at aa 38-60 272560021776 mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997 272560021777 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930 272560021778 active site 272560021779 FMN binding site [chemical binding]; other site 272560021780 2,4-decadienoyl-CoA binding site; other site 272560021781 catalytic residue [active] 272560021782 4Fe-4S cluster binding site [ion binding]; other site 272560021783 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560021784 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 36.9, E-value 1.9e-08 272560021785 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 382.7, E-value 2.3e-112 272560021786 Predicted transcriptional regulators [Transcription]; Region: COG1695 272560021787 Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400 272560021788 Pfam match to entry PF03551 PadR, Transcriptional regulator PadR-like family , score 40.3, E-value 2.9e-09 272560021789 4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170 272560021790 substrate binding site [chemical binding]; other site 272560021791 multimerization interface [polypeptide binding]; other site 272560021792 ATP binding site [chemical binding]; other site 272560021793 Pfam match to entry PF02110 HK, Hydroxyethylthiazole kinase , score 186.3, E-value 3.1e-53 272560021794 Signal peptide predicted for BPSS1136 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.981 between residues 21 and 22; signal peptide 272560021795 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560021796 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560021797 substrate binding pocket [chemical binding]; other site 272560021798 active site 272560021799 iron coordination sites [ion binding]; other site 272560021800 Predicted permeases [General function prediction only]; Region: COG0679 272560021801 8 probable transmembrane helices predicted for BPSS1137 by TMHMM2.0 at aa 5-23, 27-49, 61-83, 120-142, 149-171, 186-205, 218-240 and 268-290 272560021802 Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191 272560021803 Uncharacterized conserved protein (DUF2249); Region: DUF2249; pfam10006 272560021804 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560021805 Ligand Binding Site [chemical binding]; other site 272560021806 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560021807 Ligand Binding Site [chemical binding]; other site 272560021808 Pfam match to entry PF00582 Usp, Universal stress protein family , score 17.2, E-value 9.1e-05 272560021809 Pfam match to entry PF00582 Usp, Universal stress protein family , score 41.5, E-value 1.2e-09 272560021810 NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; cl17194 272560021811 Pfam match to entry PF01058 oxidored_q6, NADH ubiquinone oxidoreductase, 20 Kd subunit , score 133.8, E-value 2e-37 272560021812 Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl19197 272560021813 Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261 272560021814 Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Region: Complex1_49kDa; cl19174 272560021815 Pfam match to entry PF00346 complex1_49Kd, Respiratory-chain NADH dehydrogenase, 49 Kd subunit , score -101.9, E-value 1.4e-05 272560021816 hydrogenase 4 subunit F; Validated; Region: PRK06458 272560021817 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 272560021818 13 probable transmembrane helices predicted for BPSS1144 by TMHMM2.0 at aa 5-24, 31-50, 65-87, 108-127, 132-151, 163-185, 211-230, 243-265, 280-299, 318-340, 382-404, 411-433 and 455-477 272560021819 Pfam match to entry PF00361 oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains , score 136.9, E-value 2.4e-38 272560021820 Signal peptide predicted for BPSS1145 by SignalP 2.0 HMM (Signal peptide probability 0.789) with cleavage site probability 0.536 between residues 22 and 23; signal peptide 272560021821 Hydrogenase 4 membrane component (E) [Energy production and conversion]; Region: HyfE; cl17899 272560021822 7 probable transmembrane helices predicted for BPSS1145 by TMHMM2.0 at aa 4-25, 32-54, 59-81, 94-116, 126-143, 150-172 and 177-199 272560021823 NADH dehydrogenase; Region: NADHdh; cl00469 272560021824 8 probable transmembrane helices predicted for BPSS1146 by TMHMM2.0 at aa 6-28, 72-91, 101-123, 136-158, 173-192, 230-252, 258-280 and 293-315 272560021825 Pfam match to entry PF00146 NADHdh, NADH dehydrogenase , score -88.3, E-value 1.2e-06 272560021826 Signal peptide predicted for BPSS1147 by SignalP 2.0 HMM (Signal peptide probability 0.615) with cleavage site probability 0.185 between residues 21 and 22; signal peptide 272560021827 hydrogenase 4 subunit B; Validated; Region: PRK06521 272560021828 NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361 272560021829 16 probable transmembrane helices predicted for BPSS1147 by TMHMM2.0 at aa 4-26, 38-60, 82-104, 111-133, 139-161, 168-190, 210-232, 244-266, 271-293, 305-327, 342-364, 377-399, 435-457, 478-497, 530-552 and 647-665 272560021830 PS00211 ABC transporters family signature. 272560021831 Pfam match to entry PF00361 oxidored_q1, NADH-Ubiquinone/plastoquinone (complex I), various chains , score 161.1, E-value 1.2e-45 272560021832 Signal peptide predicted for BPSS1148 by SignalP 2.0 HMM (Signal peptide probability 0.817) with cleavage site probability 0.720 between residues 35 and 36; signal peptide 272560021833 Protein of unknown function (DUF1275); Region: DUF1275; pfam06912 272560021834 6 probable transmembrane helices predicted for BPSS1148 by TMHMM2.0 at aa 21-40, 66-88, 100-122, 126-148, 198-217 and 222-241 272560021835 Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367 272560021836 regulatory phosphorylation site [posttranslational modification]; other site 272560021837 Pfam match to entry PF00381 PTS-HPr, PTS HPr component phosphorylation site , score 47.3, E-value 2.3e-11 272560021838 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560021839 S-adenosylmethionine binding site [chemical binding]; other site 272560021840 Pfam match to entry PF01564 Spermine_synth, Spermine/spermidine synthase , score -67.6, E-value 5.5e-05 272560021841 Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402 272560021842 Pfam match to entry PF01402 HTH_4, Ribbon-helix-helix protein, copG family , score 17.4, E-value 0.00015 272560021843 Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223 272560021844 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021845 putative substrate translocation pore; other site 272560021846 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -95.9, E-value 0.00018 272560021847 11 probable transmembrane helices predicted for BPSS1154 by TMHMM2.0 at aa 21-43, 84-106, 113-135, 150-172, 179-196, 223-241, 248-270, 285-304, 325-347, 362-384 and 391-413 272560021848 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560021849 Pfam match to entry PF00639 Rotamase, PPIC-type PPIASE domain , score 38.0, E-value 1.4e-08 272560021850 Nitrate reductase gamma subunit; Region: Nitrate_red_gam; pfam02665 272560021851 Pfam match to entry PF02665 Nitrate_red_gam, Nitrate reductase gamma subunit , score 213.1, E-value 2.8e-61 272560021852 5 probable transmembrane helices predicted for BPSS1156 by TMHMM2.0 at aa 35-57, 85-104, 119-141, 158-180 and 219-241 272560021853 Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958 272560021854 Pfam match to entry PF02613 Nitrate_red_del, Nitrate reductase delta subunit , score 187.6, E-value 1.3e-53 272560021855 Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140 272560021856 LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cl00700 272560021857 dimer interface [polypeptide binding]; other site 272560021858 4Fe-4S dicluster domain; Region: Fer4_11; pfam13247 272560021859 Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711 272560021860 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 9.2, E-value 0.0062 272560021861 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 9.4, E-value 0.0059 272560021862 PS00190 Cytochrome c family heme-binding site signature. 272560021863 Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013 272560021864 Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710 272560021865 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750 272560021866 [4Fe-4S] binding site [ion binding]; other site 272560021867 molybdopterin cofactor binding site [chemical binding]; other site 272560021868 Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776 272560021869 molybdopterin cofactor binding site; other site 272560021870 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 149.0, E-value 5.2e-42 272560021871 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 423.8, E-value 1e-124 272560021872 PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 272560021873 PS00017 ATP/GTP-binding site motif A (P-loop). 272560021874 CHASE domain; Region: CHASE; cl01369 272560021875 PAS domain S-box; Region: sensory_box; TIGR00229 272560021876 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560021877 putative active site [active] 272560021878 heme pocket [chemical binding]; other site 272560021879 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585 272560021880 Histidine kinase; Region: HisKA_3; pfam07730 272560021881 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560021882 ATP binding site [chemical binding]; other site 272560021883 Mg2+ binding site [ion binding]; other site 272560021884 G-X-G motif; other site 272560021885 Pfam match to entry PF00989 PAS, PAS domain , score 36.0, E-value 5.5e-08 272560021886 Pfam match to entry PF00785 PAC, PAC motif , score 17.1, E-value 0.00024 272560021887 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 73.8, E-value 2.4e-19 272560021888 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560021889 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560021890 active site 272560021891 phosphorylation site [posttranslational modification] 272560021892 intermolecular recognition site; other site 272560021893 dimerization interface [polypeptide binding]; other site 272560021894 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560021895 DNA binding residues [nucleotide binding] 272560021896 dimerization interface [polypeptide binding]; other site 272560021897 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 131.3, E-value 1.1e-36 272560021898 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 82.8, E-value 4.7e-22 272560021899 Predicted helix-turn-helix motif with score 1684.000, SD 4.92 at aa 164-185, sequence ETITEIAQALDVSAKTVSTYKA 272560021900 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560021901 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560021902 active site 272560021903 phosphorylation site [posttranslational modification] 272560021904 intermolecular recognition site; other site 272560021905 dimerization interface [polypeptide binding]; other site 272560021906 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 44.7, E-value 1.3e-10 272560021907 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 272560021908 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560021909 ligand binding site [chemical binding]; other site 272560021910 flexible hinge region; other site 272560021911 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 272560021912 putative switch regulator; other site 272560021913 non-specific DNA interactions [nucleotide binding]; other site 272560021914 DNA binding site [nucleotide binding] 272560021915 sequence specific DNA binding site [nucleotide binding]; other site 272560021916 putative cAMP binding site [chemical binding]; other site 272560021917 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 46.2, E-value 4.6e-11 272560021918 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family , score 50.2, E-value 3e-12 272560021919 Predicted helix-turn-helix motif with score 1732.000, SD 5.09 at aa 212-233, sequence MTREEIGCYLGMKLETVSRMLS 272560021920 X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129 272560021921 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560021922 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530 272560021923 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560021924 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560021925 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 98.5, E-value 8.6e-27 272560021926 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560021927 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560021928 putative substrate translocation pore; other site 272560021929 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -86.0, E-value 8.2e-05 272560021930 12 probable transmembrane helices predicted for BPSS1166 by TMHMM2.0 at aa 9-31, 46-68, 80-102, 106-123, 136-158, 162-184, 218-240, 250-269, 276-298, 313-335, 342-364 and 374-396 272560021931 PS00213 Lipocalin signature. 272560021932 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560021933 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560021934 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 139.8, E-value 3.2e-39 272560021935 Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508 272560021936 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 43.6, E-value 2.9e-10 272560021937 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560021938 Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446 272560021939 Predicted membrane protein (DUF2070); Region: DUF2070; pfam09843 272560021940 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 18.4, E-value 1.6e-05 272560021941 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021942 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021943 active site 272560021944 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021945 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 20.9, E-value 2.4e-05 272560021946 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 281.5, E-value 6.9e-82 272560021947 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 236.3, E-value 2.9e-68 272560021948 PS00606 Beta-ketoacyl synthases active site. 272560021949 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Saframycin A gene cluster from Streptomyces lavendulae; Region: A_NRPS_Sfm_like; cd12115 272560021950 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560021951 acyl-activating enzyme (AAE) consensus motif; other site 272560021952 AMP binding site [chemical binding]; other site 272560021953 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021954 Condensation domain; Region: Condensation; cl19241 272560021955 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560021956 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021957 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 43.1, E-value 4.1e-10 272560021958 Pfam match to entry PF00668 Condensation, Condensation domain , score 144.3, E-value 1.4e-40 272560021959 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 60.9, E-value 1.8e-15 272560021960 PS00012 Phosphopantetheine attachment site. 272560021961 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 375.8, E-value 2.9e-110 272560021962 PS00455 AMP-binding domain signature. 272560021963 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021964 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021965 active site 272560021966 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560021967 short chain dehydrogenase; Region: adh_short; pfam00106 272560021968 NAD(P) binding site [chemical binding]; other site 272560021969 active site 272560021970 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021971 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 47.2, E-value 2.3e-11 272560021972 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 268.8, E-value 4.6e-78 272560021973 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 252.8, E-value 3.1e-73 272560021974 PS00606 Beta-ketoacyl synthases active site. 272560021975 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560021976 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560021977 active site 272560021978 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 272560021979 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560021980 short chain dehydrogenase; Region: adh_short; pfam00106 272560021981 NAD(P) binding site [chemical binding]; other site 272560021982 active site 272560021983 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021984 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 72.4, E-value 6.2e-19 272560021985 PS00012 Phosphopantetheine attachment site. 272560021986 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 150.8, E-value 1.5e-42 272560021987 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 270.1, E-value 1.9e-78 272560021988 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 199.4, E-value 3.7e-57 272560021989 PS00606 Beta-ketoacyl synthases active site. 272560021990 Condensation domain; Region: Condensation; cl19241 272560021991 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560021992 The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116 272560021993 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560021994 acyl-activating enzyme (AAE) consensus motif; other site 272560021995 AMP binding site [chemical binding]; other site 272560021996 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560021997 Condensation domain; Region: Condensation; cl19241 272560021998 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560021999 Pfam match to entry PF00668 Condensation, Condensation domain , score 73.3, E-value 3.2e-19 272560022000 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 40.4, E-value 2.6e-09 272560022001 PS00012 Phosphopantetheine attachment site. 272560022002 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 412.4, E-value 2.8e-121 272560022003 PS00455 AMP-binding domain signature. 272560022004 Pfam match to entry PF00668 Condensation, Condensation domain , score 119.8, E-value 3.4e-33 272560022005 Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339 272560022006 Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456 272560022007 active site 272560022008 Zn binding site [ion binding]; other site 272560022009 Pfam match to entry PF01432 Peptidase_M3, Peptidase M3 , score 497.6, E-value 6.2e-147 272560022010 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560022011 DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188 272560022012 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560022013 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560022014 DNA binding residues [nucleotide binding] 272560022015 dimerization interface [polypeptide binding]; other site 272560022016 Pfam match to entry PF03472 Autoind_bind, Autoinducer binding domain , score 104.8, E-value 1.1e-28 272560022017 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 68.0, E-value 1.3e-17 272560022018 PS00622 Bacterial regulatory proteins, luxR family signature. 272560022019 Predicted helix-turn-helix motif with score 1557.000, SD 4.49 at aa 189-210, sequence KTAYEIALILSISESTVNFHVK 272560022020 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560022021 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475 272560022022 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 10.1, E-value 1.7e-06 272560022023 11 probable transmembrane helices predicted for BPSS1178 by TMHMM2.0 at aa 42-61, 73-95, 105-127, 140-159, 174-196, 208-230, 240-262, 281-303, 356-378, 398-415 and 419-441 272560022024 Autoinducer synthetase; Region: Autoind_synth; cl17404 272560022025 Pfam match to entry PF00765 Autoind_synth, Autoinducer synthetase , score 31.5, E-value 1.9e-11 272560022026 PS00949 Autoinducers synthetases family signature. 272560022027 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 272560022028 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560022029 acyl-activating enzyme (AAE) consensus motif; other site 272560022030 AMP binding site [chemical binding]; other site 272560022031 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 467.3, E-value 8e-138 272560022032 PS00455 AMP-binding domain signature. 272560022033 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022034 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 38.8, E-value 7.8e-09 272560022035 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 272560022036 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022037 Gene remnant. Similar to the C-terminal region of Escherichia coli shikimate transporter ShiA SWALL:SHIA_ECOLI (SWALL:P76350) (438 aa) fasta scores: E(): 3.2e-20, 40.65% id in 214 aa. CDS contains at least two frameshift mutations; shikimate transporter (fragment) 272560022038 1 probable transmembrane helix predicted for BPSS1186 by TMHMM2.0 at aa 82-104 272560022039 beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family; Region: pcaR_pcaU; TIGR02431 272560022040 Similar to Myxococcus xanthus saframycin MX1 synthetase B SafB SWALL:Q50857 (EMBL:U24657) (1770 aa) fasta scores: E(): 1.8e-69, 38.67% id in 693 aa, and to Streptomyces coelicolor polyketide synthase sco5892 or sc3f7.12 SWALL:O54155 (EMBL:AL939125) (2297 aa) fasta scores: E(): 9.4e-61, 38.36% id in 756 aa, and to Streptomyces atroolivaceus nonribosomal peptide synthetase SWALL:AAN85512 (EMBL:AF484556) (1745 aa) fasta scores: E(): 3.4e-60, 38.96% id in 693 aa. CDS contains a frameshift mutation after codon 605. This CDS prematurely terminates.; non ribosomal peptide/polyketide synthase (pseudogene) 272560022041 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 47.0, E-value 2.8e-11 272560022042 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 253.0, E-value 2.6e-73 272560022043 PS00455 AMP-binding domain signature. 272560022044 Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl19096 272560022045 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score 28.9, E-value 2.2e-10 272560022046 Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342 272560022047 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560022048 catalytic residue [active] 272560022049 Condensation domain; Region: Condensation; cl19241 272560022050 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Streptoalloteichus tallysomycin biosynthesis genes; Region: A_NRPS_TlmIV_like; cd12114 272560022051 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560022052 acyl-activating enzyme (AAE) consensus motif; other site 272560022053 AMP binding site [chemical binding]; other site 272560022054 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022055 Condensation domain; Region: Condensation; pfam00668 272560022056 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560022057 Pfam match to entry PF00668 Condensation, Condensation domain , score 235.5, E-value 4.9e-68 272560022058 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 67.2, E-value 2.3e-17 272560022059 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 444.5, E-value 5.9e-131 272560022060 PS00455 AMP-binding domain signature. 272560022061 Pfam match to entry PF00668 Condensation, Condensation domain , score 201.8, E-value 6.8e-58 272560022062 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560022063 acyl-activating enzyme (AAE) consensus motif; other site 272560022064 AMP binding site [chemical binding]; other site 272560022065 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022066 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 272560022067 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 110.1, E-value 2.7e-30 272560022068 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 77.6, E-value 1.7e-20 272560022069 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 387.8, E-value 7.2e-114 272560022070 PS00455 AMP-binding domain signature. 272560022071 Condensation domain; Region: Condensation; cl19241 272560022072 Pfam match to entry PF00668 Condensation, Condensation domain , score -14.2, E-value 3.6e-09 272560022073 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560022074 substrate binding pocket [chemical binding]; other site 272560022075 active site 272560022076 iron coordination sites [ion binding]; other site 272560022077 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560022078 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560022079 active site 272560022080 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 272560022081 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022082 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560022083 inhibitor-cofactor binding pocket; inhibition site 272560022084 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560022085 catalytic residue [active] 272560022086 Condensation domain; Region: Condensation; cl19241 272560022087 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560022088 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560022089 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560022090 acyl-activating enzyme (AAE) consensus motif; other site 272560022091 AMP binding site [chemical binding]; other site 272560022092 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022093 Condensation domain; Region: Condensation; cl19241 272560022094 non-ribosomal peptide synthase domain TIGR01720; Region: NRPS-para261 272560022095 Pfam match to entry PF00668 Condensation, Condensation domain , score 75.8, E-value 5.8e-20 272560022096 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 64.7, E-value 1.2e-16 272560022097 PS00012 Phosphopantetheine attachment site. 272560022098 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 324.6, E-value 7.2e-95 272560022099 PS00216 Sugar transport proteins signature 1. 272560022100 PS00455 AMP-binding domain signature. 272560022101 Pfam match to entry PF00668 Condensation, Condensation domain , score 73.4, E-value 3.2e-19 272560022102 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560022103 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 173.3, E-value 2.6e-49 272560022104 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 64.0, E-value 2.1e-16 272560022105 PS00012 Phosphopantetheine attachment site. 272560022106 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 254.3, E-value 1.1e-73 272560022107 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 253.4, E-value 2e-73 272560022108 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 371.4, E-value 6e-109 272560022109 PS00606 Beta-ketoacyl synthases active site. 272560022110 Signal peptide predicted for BPSS1198 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.985 between residues 17 and 18; signal peptide 272560022111 major capsid protein; Region: PHA00665 272560022112 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560022113 DNA-binding site [nucleotide binding]; DNA binding site 272560022114 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560022115 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560022116 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560022117 homodimer interface [polypeptide binding]; other site 272560022118 catalytic residue [active] 272560022119 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 62.8, E-value 4.7e-16 272560022120 Predicted helix-turn-helix motif with score 1252.000, SD 3.45 at aa 59-80, sequence PSTRELARQLGVSRKTTLDAFE 272560022121 Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627 272560022122 Uncharacterized conserved protein [Function unknown]; Region: COG2128 272560022123 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917 272560022124 aspartate carbamoyltransferase; Provisional; Region: PRK11891 272560022125 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729 272560022126 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185 272560022127 Predicted helix-turn-helix motif with score 1325.000, SD 3.70 at aa 18-39, sequence MTREAFANRIGVSRRALDTWLL 272560022128 Pfam match to entry PF02729 OTCace_N, Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain , score 173.6, E-value 2.1e-49 272560022129 PS00097 Aspartate and ornithine carbamoyltransferases signature. 272560022130 Pfam match to entry PF00185 OTCace, Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain , score 128.9, E-value 6.1e-36 272560022131 Signal peptide predicted for BPSS1204 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 20 and 21; signal peptide 272560022132 Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; Region: Fiu; COG4774 272560022133 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560022134 N-terminal plug; other site 272560022135 ligand-binding site [chemical binding]; other site 272560022136 PS00443 Glutamine amidotransferases class-II active site. 272560022137 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 85.9, E-value 5.3e-23 272560022138 FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790 272560022139 Sel1-like repeats; Region: SEL1; smart00671 272560022140 Sel1-like repeats; Region: SEL1; smart00671 272560022141 Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467 272560022142 Pfam match to entry PF03171 2OG-FeII_Oxy, 2OG-Fe(II) oxygenase superfamily , score 34.9, E-value 1.2e-07 272560022143 C-terminus similar to Burkholderia cepacia transposase SWALL:Q45111 (EMBL:U44828) (419 aa) fasta scores: E(): 3.9e-27, 95.58% id in 68 aa, and C-terminus similar to Burkholderia cepacia transposase Tnp SWALL:Q9ZFQ7 (EMBL:AF095748) (419 aa) fasta scores: E(): 3.9e-27, 95.58% id in 68 aa, and to Ralstonia solanacearum ISRso7-transposase rsp0478 or rs00356 or rsc0252 or rs00687 SWALL:Q8XEN1 (EMBL:AL646078) (416 aa) fasta scores: E(): 1.5e-17, 70.31% id in 64 aa;transposase (fragment) 272560022144 Pfam match to entry PF00872 Transpo_mutator, Transposase, Mutator family , score 65.8, E-value 5.2e-19 272560022145 Similar to an internal region of Mycobacterium avium transposase subunit B SWALL:Q933U0 (EMBL:AF232829) (306 aa) fasta scores: E(): 2.4e-06, 31.2% id in 125 aa, and to Bradyrhizobium japonicum id60 rsbeta3 SWALL:Q9ANN7 (EMBL:AF322012) (211 aa) fasta scores: E(): 4.2e-29, 63.35% id in 131 aa; transposase (fragment) 272560022146 Pfam match to entry PF00665 rve, Integrase core domain , score 19.2, E-value 1.5e-05 272560022147 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 272560022148 Transposase; Region: HTH_Tnp_1; cl17663 272560022149 Pfam match to entry PF01527 Transposase_8, Transposase , score 32.1, E-value 8.5e-07 272560022150 Predicted helix-turn-helix motif with score 1913.000, SD 5.70 at aa 26-47, sequence RTLAELAQQFDVHPNQITEWKR 272560022151 Uncharacterized conserved protein [Function unknown]; Region: COG4104 272560022152 Protein of unknown function (DUF2875); Region: DUF2875; pfam11394 272560022153 1 probable transmembrane helix predicted for BPSS1211 by TMHMM2.0 at aa 35-54 272560022154 Protein of unknown function (DUF3274); Region: DUF3274; pfam11678 272560022155 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022156 PS00120 Lipases, serine active site. 272560022157 Uncharacterized protein conserved in bacteria [Function unknown]; Region: VgrG; COG3501 272560022158 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560022159 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560022160 Putative type VI secretion system Rhs element Vgr; Region: T6SS_Vgr; pfam13296 272560022161 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4253 272560022162 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022163 helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421 272560022164 DNA binding residues [nucleotide binding] 272560022165 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 21.5, E-value 1.6e-05 272560022166 Predicted helix-turn-helix motif with score 1527.000, SD 4.39 at aa 179-200, sequence LTNKEISRLLGISDRTVECHCA 272560022167 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022168 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560022169 putative substrate translocation pore; other site 272560022170 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -34.8, E-value 1.4e-06 272560022171 12 probable transmembrane helices predicted for BPSS1215 by TMHMM2.0 at aa 12-31, 51-73, 80-102, 117-136, 149-171, 191-208, 229-251, 266-288, 300-322, 326-348, 361-383 and 388-410 272560022172 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 272560022173 thiamine phosphate binding site [chemical binding]; other site 272560022174 active site 272560022175 pyrophosphate binding site [ion binding]; other site 272560022176 Pfam match to entry PF02581 TMP-TENI, Thiamine monophosphate synthase/TENI , score 42.3, E-value 9e-11 272560022177 Signal peptide predicted for BPSS1217 by SignalP 2.0 HMM (Signal peptide probability 0.613) with cleavage site probability 0.391 between residues 27 and 28; signal peptide 272560022178 GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182 272560022179 Ligand binding site; other site 272560022180 metal-binding site 272560022181 Signal peptide predicted for BPSS1218 by SignalP 2.0 HMM (Signal peptide probability 0.981) with cleavage site probability 0.424 between residues 31 and 32; signal peptide 272560022182 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4564 272560022183 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 272560022184 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560022185 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560022186 dimer interface [polypeptide binding]; other site 272560022187 putative CheW interface [polypeptide binding]; other site 272560022188 2 probable transmembrane helices predicted for BPSS1218 by TMHMM2.0 at aa 10-32 and 191-213 272560022189 Pfam match to entry PF00672 HAMP, HAMP domain , score 22.5, E-value 0.00063 272560022190 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 352.3, E-value 3.5e-103 272560022191 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 272560022192 Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717 272560022193 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 272560022194 1 probable transmembrane helix predicted for BPSS1219 by TMHMM2.0 at aa 45-64 272560022195 Pfam match to entry PF03717 PBP_dimer, Penicillin-binding Protein dimerisation domain , score 155.0, E-value 8.7e-44 272560022196 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 326.4, E-value 2.2e-95 272560022197 PS00107 Protein kinases ATP-binding region signature. 272560022198 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022199 Signal peptide predicted for BPSS1220 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.978 between residues 27 and 28; signal peptide 272560022200 Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540 272560022201 Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532 272560022202 ligand binding site [chemical binding]; other site 272560022203 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 108.4, E-value 9.1e-30 272560022204 Signal peptide predicted for BPSS1221 by SignalP 2.0 HMM (Signal peptide probability 0.834) with cleavage site probability 0.452 between residues 23 and 24; signal peptide 272560022205 short chain dehydrogenase; Provisional; Region: PRK07074 272560022206 classical (c) SDRs; Region: SDR_c; cd05233 272560022207 NAD(P) binding site [chemical binding]; other site 272560022208 active site 272560022209 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 183.1, E-value 2.9e-52 272560022210 putative cation:proton antiport protein; Provisional; Region: PRK10669 272560022211 Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482 272560022212 Signal peptide predicted for BPSS1222 by SignalP 2.0 HMM (Signal peptide probability 0.943) with cleavage site probability 0.546 between residues 25 and 26; signal peptide 272560022213 TrkA-N domain; Region: TrkA_N; pfam02254 272560022214 Pfam match to entry PF02254 TrkA-N, TrkA-N domain , score 58.5, E-value 9.6e-15 272560022215 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score -5.1, E-value 4.6e-06 272560022216 11 probable transmembrane helices predicted for BPSS1222 by TMHMM2.0 at aa 5-27, 34-56, 60-82, 87-109, 114-136, 149-171, 196-218, 238-255, 317-339, 346-368 and 383-405 272560022217 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022218 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560022219 1 probable transmembrane helix predicted for BPSS1223 by TMHMM2.0 at aa 194-213 272560022220 Signal peptide predicted for BPSS1224 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.508 between residues 26 and 27; signal peptide 272560022221 Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620 272560022222 Streptogramin lyase [Defense mechanisms]; Region: Vgb; COG4257 272560022223 1 probable transmembrane helix predicted for BPSS1224 by TMHMM2.0 at aa 12-34 272560022224 PS00190 Cytochrome c family heme-binding site signature. 272560022225 Signal peptide predicted for BPSS1225 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.613 between residues 31 and 32; signal peptide 272560022226 3 probable transmembrane helices predicted for BPSS1225 by TMHMM2.0 at aa 6-28, 49-66 and 81-103 272560022227 Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588 272560022228 dimer interface [polypeptide binding]; other site 272560022229 CorA-like Mg2+ transporter protein; Region: CorA; pfam01544 272560022230 Uncharacterized bacterial subgroup of the Salmonella typhimurium Zn2+ transporter ZntB-like subfamily; Region: ZntB_u1; cd12834 272560022231 Cl binding site [ion binding]; other site 272560022232 oligomer interface [polypeptide binding]; other site 272560022233 Pfam match to entry PF01544 CorA, CorA-like Mg2+ transporter protein , score -10.3, E-value 2.9e-08 272560022234 2 probable transmembrane helices predicted for BPSS1228 by TMHMM2.0 at aa 279-301 and 316-335 272560022235 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 272560022236 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531 272560022237 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 272560022238 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family , score 141.6, E-value 8.9e-40 272560022239 Predicted helix-turn-helix motif with score 1136.000, SD 3.06 at aa 23-44, sequence VQAAALAAEFHVSEDAIRRDLR 272560022240 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022241 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560022242 putative substrate translocation pore; other site 272560022243 12 probable transmembrane helices predicted for BPSS1230 by TMHMM2.0 at aa 21-40, 50-72, 77-99, 104-126, 139-161, 166-185, 206-225, 240-262, 275-294, 298-317, 330-352 and 362-381 272560022244 Signal peptide predicted for BPSS1231 by SignalP 2.0 HMM (Signal peptide probability 0.921) with cleavage site probability 0.793 between residues 30 and 31; signal peptide 272560022245 Electron transfer DM13; Region: DM13; pfam10517 272560022246 1 probable transmembrane helix predicted for BPSS1231 by TMHMM2.0 at aa 12-31 272560022247 Signal peptide predicted for BPSS1232 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.782 between residues 23 and 24; signal peptide 272560022248 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 272560022249 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560022250 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560022251 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 157.7, E-value 1.3e-44 272560022252 Signal peptide predicted for BPSS1233 by SignalP 2.0 HMM (Signal peptide probability 0.941) with cleavage site probability 0.580 between residues 31 and 32; signal peptide 272560022253 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560022254 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560022255 dimer interface [polypeptide binding]; other site 272560022256 conserved gate region; other site 272560022257 putative PBP binding loops; other site 272560022258 ABC-ATPase subunit interface; other site 272560022259 7 probable transmembrane helices predicted for BPSS1233 by TMHMM2.0 at aa 15-37, 72-94, 104-121, 128-150, 155-177, 198-220 and 262-284 272560022260 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 42.9, E-value 4.7e-10 272560022261 Signal peptide predicted for BPSS1234 by SignalP 2.0 HMM (Signal peptide probability 0.905) with cleavage site probability 0.843 between residues 28 and 29; signal peptide 272560022262 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 272560022263 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560022264 dimer interface [polypeptide binding]; other site 272560022265 conserved gate region; other site 272560022266 putative PBP binding loops; other site 272560022267 ABC-ATPase subunit interface; other site 272560022268 6 probable transmembrane helices predicted for BPSS1234 by TMHMM2.0 at aa 7-29, 72-94, 106-128, 138-160, 180-202 and 238-260 272560022269 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 41.6, E-value 1.2e-09 272560022270 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560022271 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560022272 Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285 272560022273 inhibitor binding site; inhibition site 272560022274 catalytic Zn binding site [ion binding]; other site 272560022275 structural Zn binding site [ion binding]; other site 272560022276 NADP binding site [chemical binding]; other site 272560022277 tetramer interface [polypeptide binding]; other site 272560022278 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 262.2, E-value 4.7e-76 272560022279 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560022280 1 probable transmembrane helix predicted for BPSS1235 by TMHMM2.0 at aa 168-190 272560022281 glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650 272560022282 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 272560022283 Walker A/P-loop; other site 272560022284 ATP binding site [chemical binding]; other site 272560022285 Q-loop/lid; other site 272560022286 ABC transporter signature motif; other site 272560022287 Walker B; other site 272560022288 D-loop; other site 272560022289 H-loop/switch region; other site 272560022290 TOBE domain; Region: TOBE_2; pfam08402 272560022291 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 217.2, E-value 1.6e-62 272560022292 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022293 PS00211 ABC transporters family signature. 272560022294 Pfam match to entry PF03459 TOBE, TOBE domain , score 40.5, E-value 2.5e-09 272560022295 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560022296 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560022297 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560022298 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 35.2, E-value 9.5e-08 272560022299 Predicted helix-turn-helix motif with score 1443.000, SD 4.10 at aa 212-233, sequence LREADVAEFAGMSVSTFTRFFR 272560022300 PS00041 Bacterial regulatory proteins, araC family signature. 272560022301 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 25.9, E-value 6e-05 272560022302 Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808 272560022303 N- and C-terminal domain interface [polypeptide binding]; other site 272560022304 active site 272560022305 MgATP binding site [chemical binding]; other site 272560022306 catalytic site [active] 272560022307 metal binding site [ion binding]; metal-binding site 272560022308 xylulose binding site [chemical binding]; other site 272560022309 homodimer interface [polypeptide binding]; other site 272560022310 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 310.1, E-value 1.7e-90 272560022311 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 154.1, E-value 1.5e-43 272560022312 PS00445 FGGY family of carbohydrate kinases signature 2. 272560022313 D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686 272560022314 Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191 272560022315 Pfam match to entry PF00768 Peptidase_S11, D-alanyl-D-alanine carboxypeptidase , score 272.0, E-value 5.1e-79 272560022316 Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768 272560022317 Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717 272560022318 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905 272560022319 Pfam match to entry PF03717 PBP_dimer, Penicillin-binding Protein dimerisation domain , score 108.3, E-value 1e-29 272560022320 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 286.5, E-value 2.3e-83 272560022321 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754 272560022322 formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591 272560022323 [4Fe-4S] binding site [ion binding]; other site 272560022324 molybdopterin cofactor binding site; other site 272560022325 Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791 272560022326 molybdopterin cofactor binding site; other site 272560022327 Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369 272560022328 Flavodoxin; Region: Flavodoxin_1; pfam00258 272560022329 Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199 272560022330 FAD binding pocket [chemical binding]; other site 272560022331 FAD binding motif [chemical binding]; other site 272560022332 catalytic residues [active] 272560022333 NAD binding pocket [chemical binding]; other site 272560022334 phosphate binding motif [ion binding]; other site 272560022335 beta-alpha-beta structure motif; other site 272560022336 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 132.0, E-value 7.3e-37 272560022337 Pfam match to entry PF00667 FAD_binding_1, FAD binding domain , score 126.3, E-value 3.6e-35 272560022338 Pfam match to entry PF00258 flavodoxin, Flavodoxin , score 132.9, E-value 3.7e-37 272560022339 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 151.8, E-value 7.5e-43 272560022340 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 435.5, E-value 3.1e-128 272560022341 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560022342 Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529 272560022343 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 8.5, E-value 0.00016 272560022344 nitrite reductase subunit NirD; Provisional; Region: PRK14989 272560022345 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560022346 BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324 272560022347 Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460 272560022348 Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077 272560022349 Pfam match to entry PF01077 NIR_SIR, Nitrite and sulphite reductase 4Fe-4S domain , score 110.2, E-value 2.6e-30 272560022350 PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 272560022351 Pfam match to entry PF03460 NIR_SIR_ferr, Nitrite/Sulfite reductase ferredoxin-like half domain , score 87.8, E-value 1.4e-23 272560022352 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 226.6, E-value 2.4e-65 272560022353 nitrite extrusion protein (nitrite facilitator); Region: 2A0108; TIGR00886 272560022354 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022355 putative substrate translocation pore; other site 272560022356 12 probable transmembrane helices predicted for BPSS1244 by TMHMM2.0 at aa 23-45, 55-74, 86-103, 107-129, 150-172, 177-199, 244-266, 276-298, 311-333, 337-359, 366-388 and 398-420 272560022357 Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642 272560022358 active site 272560022359 SAM binding site [chemical binding]; other site 272560022360 homodimer interface [polypeptide binding]; other site 272560022361 Pfam match to entry PF00590 TP_methylase, Tetrapyrrole (Corrin/Porphyrin) Methylases , score 236.0, E-value 3.5e-68 272560022362 PS00839 Uroporphyrin-III C-methyltransferase signature 1. 272560022363 Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707 272560022364 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560022365 active site 272560022366 phosphorylation site [posttranslational modification] 272560022367 intermolecular recognition site; other site 272560022368 dimerization interface [polypeptide binding]; other site 272560022369 ANTAR domain; Region: ANTAR; pfam03861 272560022370 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 22.9, E-value 9e-06 272560022371 Pfam match to entry PF03861 ANTAR, ANTAR domain , score 56.6, E-value 3.6e-14 272560022372 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715 272560022373 NMT1-like family; Region: NMT1_2; pfam13379 272560022374 GTP cyclohydrolase I; Reviewed; Region: PRK12606 272560022375 active site 272560022376 Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I , score 74.6, E-value 1.3e-19 272560022377 Glycogen debranching enzyme [Carbohydrate transport and metabolism]; Region: GDB1; COG3408 272560022378 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560022379 Histone deacetylase class IIa; Region: HDAC_classII_APAH; cd10001 272560022380 active site 272560022381 Zn binding site [ion binding]; other site 272560022382 Pfam match to entry PF00850 Hist_deacetyl, Histone deacetylase , score 196.5, E-value 2.6e-56 272560022383 allantoate amidohydrolase; Reviewed; Region: PRK12893 272560022384 M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884 272560022385 active site 272560022386 metal binding site [ion binding]; metal-binding site 272560022387 dimer interface [polypeptide binding]; other site 272560022388 Pfam match to entry PF01546 Peptidase_M20, Peptidase M20/M25/M40 , score 105.9, E-value 5.1e-29 272560022389 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022390 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560022391 putative substrate translocation pore; other site 272560022392 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 75.2, E-value 8.7e-20 272560022393 12 probable transmembrane helices predicted for BPSS1252 by TMHMM2.0 at aa 27-49, 64-86, 95-117, 127-149, 161-183, 193-215, 248-270, 285-307, 314-336, 341-363, 376-398 and 403-425 272560022394 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 272560022395 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560022396 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560022397 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560022398 dimerization interface [polypeptide binding]; other site 272560022399 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 79.6, E-value 4.2e-21 272560022400 Predicted helix-turn-helix motif with score 1924.000, SD 5.74 at aa 20-41, sequence RSISRAAARLHLTQPAVSQALK 272560022401 PS00044 Bacterial regulatory proteins, lysR family signature. 272560022402 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 104.9, E-value 1e-28 272560022403 Similar to N-terminus of Caulobacter crescentus aspartate racemase cc3278 SWALL:Q9A3C6 (EMBL:AE005991) (253 aa) fasta scores: E(): 1e-09, 46.49% id in 114 aa, and to N-terminus of Rhizobium loti aspartate racemase mll4070 SWALL:Q98EV2 (EMBL:AP003003) (231 aa) fasta scores: E(): 7.8e-08, 38.98% id in 118 aa, and to N-terminus of Xanthomonas axonopodis resistance protein YgeA or xac1802 SWALL:AAM36665 (EMBL:AE011812) (234 aa) fasta scores: E(): 9.1e-08, 42.24% id in 116 aa;conserved hypothetical protein (fragment) 272560022404 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560022405 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560022406 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472 272560022407 putative effector binding pocket; other site 272560022408 putative dimerization interface [polypeptide binding]; other site 272560022409 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 175.1, E-value 7.7e-50 272560022410 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 65.8, E-value 6.2e-17 272560022411 PS00044 Bacterial regulatory proteins, lysR family signature. 272560022412 short chain dehydrogenase; Provisional; Region: PRK12937 272560022413 tetrahydroxynaphthalene/trihydroxynaphthalene reductase-like, classical (c) SDRs; Region: THN_reductase-like_SDR_c; cd05362 272560022414 NADP binding site [chemical binding]; other site 272560022415 homodimer interface [polypeptide binding]; other site 272560022416 active site 272560022417 substrate binding site [chemical binding]; other site 272560022418 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 251.1, E-value 1e-72 272560022419 PS00061 Short-chain dehydrogenases/reductases family signature. 272560022420 CoA-transferase family III; Region: CoA_transf_3; cl19215 272560022421 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560022422 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 29.0, E-value 4e-11 272560022423 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 272560022424 Prostaglandin dehydrogenases; Region: PGDH; cd05288 272560022425 NAD(P) binding site [chemical binding]; other site 272560022426 substrate binding site [chemical binding]; other site 272560022427 dimer interface [polypeptide binding]; other site 272560022428 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 136.6, E-value 3e-38 272560022429 Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187 272560022430 dimer interface [polypeptide binding]; other site 272560022431 active site 272560022432 metal binding site [ion binding]; metal-binding site 272560022433 Pfam match to entry PF00465 Fe-ADH, Iron-containing alcohol dehydrogenase , score 115.3, E-value 7.6e-32 272560022434 PS00060 Iron-containing alcohol dehydrogenases signature 2. 272560022435 PS00913 Iron-containing alcohol dehydrogenases signature 1. 272560022436 Peptidase M66; Region: Peptidase_M66; pfam10462 272560022437 Uncharacterized protein conserved in bacteria (DUF2322); Region: DUF2322; pfam10084 272560022438 Protein of unknown function (DUF3348); Region: DUF3348; pfam11828 272560022439 Signal peptide predicted for BPSS1262 by SignalP 2.0 HMM (Signal peptide probability 0.955) with cleavage site probability 0.954 between residues 25 and 26; signal peptide 272560022440 Signal peptide predicted for BPSS1263 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.472 between residues 26 and 27; signal peptide 272560022441 Domain of unknown function (DUF802); Region: DUF802; pfam05650 272560022442 Domain of unknown function (DUF802); Region: DUF802; pfam05650 272560022443 3 probable transmembrane helices predicted for BPSS1263 by TMHMM2.0 at aa 5-27, 31-48 and 107-129 272560022444 hypothetical protein; Provisional; Region: PRK09040 272560022445 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560022446 ligand binding site [chemical binding]; other site 272560022447 1 probable transmembrane helix predicted for BPSS1264 by TMHMM2.0 at aa 15-37 272560022448 Pfam match to entry PF00691 OmpA, OmpA family , score 67.9, E-value 1.4e-17 272560022449 Protein of unknown function (DUF2894); Region: DUF2894; pfam11445 272560022450 Condensation domain; Region: Condensation; cl19241 272560022451 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560022452 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560022453 acyl-activating enzyme (AAE) consensus motif; other site 272560022454 AMP binding site [chemical binding]; other site 272560022455 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022456 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 69.3, E-value 5.3e-18 272560022457 PS00012 Phosphopantetheine attachment site. 272560022458 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 566.0, E-value 1.5e-167 272560022459 PS00455 AMP-binding domain signature. 272560022460 Pfam match to entry PF00668 Condensation, Condensation domain , score 95.5, E-value 6.9e-26 272560022461 MbtH-like protein; Region: MbtH; pfam03621 272560022462 Pfam match to entry PF03621 MbtH, MbtH-like protein , score 117.3, E-value 1.8e-32 272560022463 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022464 putative substrate translocation pore; other site 272560022465 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560022466 10 probable transmembrane helices predicted for BPSS1268 by TMHMM2.0 at aa 29-51, 66-88, 97-116, 121-143, 156-178, 182-204, 241-263, 273-295, 363-385 and 395-417 272560022467 PS00216 Sugar transport proteins signature 1. 272560022468 Condensation domain; Region: Condensation; cl19241 272560022469 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560022470 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560022471 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560022472 acyl-activating enzyme (AAE) consensus motif; other site 272560022473 AMP binding site [chemical binding]; other site 272560022474 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022475 Condensation domain; Region: Condensation; cl19241 272560022476 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560022477 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560022478 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560022479 acyl-activating enzyme (AAE) consensus motif; other site 272560022480 AMP binding site [chemical binding]; other site 272560022481 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022482 Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3321 272560022483 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560022484 active site 272560022485 Acyl transferase domain in polyketide synthase (PKS) enzymes; Region: PKS_AT; smart00827 272560022486 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560022487 ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953 272560022488 short chain dehydrogenase; Region: adh_short; pfam00106 272560022489 putative NADP binding site [chemical binding]; other site 272560022490 active site 272560022491 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560022492 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 272560022493 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 77.2, E-value 2.2e-20 272560022494 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 79.6, E-value 4.3e-21 272560022495 PS00012 Phosphopantetheine attachment site. 272560022496 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 20.8, E-value 9.9e-09 272560022497 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 189.4, E-value 3.6e-54 272560022498 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 298.8, E-value 4.2e-87 272560022499 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 242.1, E-value 4.9e-70 272560022500 PS00606 Beta-ketoacyl synthases active site. 272560022501 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 80.4, E-value 2.5e-21 272560022502 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 438.1, E-value 4.9e-129 272560022503 PS00455 AMP-binding domain signature. 272560022504 Pfam match to entry PF00668 Condensation, Condensation domain , score 180.1, E-value 2.3e-51 272560022505 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 59.7, E-value 4.1e-15 272560022506 PS00012 Phosphopantetheine attachment site. 272560022507 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 410.4, E-value 1.1e-120 272560022508 PS00455 AMP-binding domain signature. 272560022509 Pfam match to entry PF00668 Condensation, Condensation domain , score 192.2, E-value 5.5e-55 272560022510 2OG-Fe dioxygenase; Region: 2OG-Fe_Oxy_2; pfam10014 272560022511 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560022512 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 46.3, E-value 4.5e-11 272560022513 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560022514 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 272560022515 active site 272560022516 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 28.8, E-value 1.8e-07 272560022517 Acyl-CoA dehydrogenase, N-terminal domain; Region: Acyl-CoA_dh_N; cl09932 272560022518 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560022519 Acyl-CoA dehydrogenase; Region: ACAD; cd00567 272560022520 active site 272560022521 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 53.2, E-value 3.6e-13 272560022522 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 36.3, E-value 1.1e-09 272560022523 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560022524 acyl-CoA synthetase; Validated; Region: PRK05850 272560022525 acyl-activating enzyme (AAE) consensus motif; other site 272560022526 active site 272560022527 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 275.1, E-value 6.1e-80 272560022528 PS00455 AMP-binding domain signature. 272560022529 1 probable transmembrane helix predicted for BPSS1274 by TMHMM2.0 at aa 82-104 272560022530 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560022531 RNA polymerase factor sigma-70; Validated; Region: PRK09047 272560022532 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560022533 DNA binding residues [nucleotide binding] 272560022534 Uncharacterized conserved protein [Function unknown]; Region: COG1739 272560022535 Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205 272560022536 Domain of unknown function (DUF1949); Region: DUF1949; pfam09186 272560022537 Pfam match to entry PF01205 UPF0029, Uncharacterized protein family UPF0029 , score 152.4, E-value 5e-43 272560022538 Signal peptide predicted for BPSS1277 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.745 between residues 27 and 28; signal peptide 272560022539 EamA-like transporter family; Region: EamA; pfam00892 272560022540 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560022541 EamA-like transporter family; Region: EamA; pfam00892 272560022542 High-affinity nickel-transport protein; Region: NicO; cl00964 272560022543 10 probable transmembrane helices predicted for BPSS1277 by TMHMM2.0 at aa 7-24, 34-56, 79-101, 106-128, 135-152, 156-175, 188-210, 220-242, 251-270 and 275-292 272560022544 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 52.1, E-value 7.8e-13 272560022545 PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 272560022546 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 20.8, E-value 0.0022 272560022547 Probable gene remnant. Similar to the C-terminal regions of Chromobacterium violaceum probable membrane transport protein SWALL:Q7NSV5 (EMBL:AE016921) (417 aa) fasta scores: E(): 1.6e-07, 33.77% id in 151 aa, and Mycobacterium paratuberculosis hypothetical protein SWALL:Q73SK8 (EMBL:AE017241) (453 aa) fasta scores: E(): 4.6e-09, 41.79% id in 134 aa; membrane protein (fragment) 272560022548 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 272560022549 Flavin containing amine oxidoreductase; Region: Amino_oxidase; pfam01593 272560022550 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560022551 Pfam match to entry PF01593 Amino_oxidase, Flavin containing amine oxidoreductase , score 112.5, E-value 5.3e-31 272560022552 PS00190 Cytochrome c family heme-binding site signature. 272560022553 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560022554 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560022555 threonine dehydratase; Reviewed; Region: PRK09224 272560022556 Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562 272560022557 tetramer interface [polypeptide binding]; other site 272560022558 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560022559 catalytic residue [active] 272560022560 First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906 272560022561 putative Ile/Val binding site [chemical binding]; other site 272560022562 Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907 272560022563 putative Ile/Val binding site [chemical binding]; other site 272560022564 Pfam match to entry PF00585 Thr_dehydrat_C, C-terminal regulatory domain of Threonine dehydratase , score 137.0, E-value 2.3e-38 272560022565 Pfam match to entry PF00585 Thr_dehydrat_C, C-terminal regulatory domain of Threonine dehydratase , score 137.2, E-value 1.9e-38 272560022566 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 354.1, E-value 9.8e-104 272560022567 PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 272560022568 polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707 272560022569 Pfam match to entry PF03976 DUF344, Domain of unknown function (DUF344) , score 563.8, E-value 7.3e-167 272560022570 Signal peptide predicted for BPSS1282 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 35 and 36; signal peptide 272560022571 Outer membrane protein W [Cell envelope biogenesis, outer membrane]; Region: OmpW; COG3047 272560022572 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560022573 type I secretion membrane fusion protein, HlyD family; Region: type_I_hlyD; TIGR01843 272560022574 Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; Region: SPEC; cd00176 272560022575 linker region; other site 272560022576 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560022577 PS00543 HlyD family secretion proteins signature. 272560022578 1 probable transmembrane helix predicted for BPSS1283 by TMHMM2.0 at aa 39-61 272560022579 Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185 272560022580 putative acyl-acceptor binding pocket; other site 272560022581 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms]; Region: SunT; COG2274 272560022582 Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic); Region: Peptidase_C39_like; cl00296 272560022583 putative active site [active] 272560022584 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560022585 ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228 272560022586 Walker A/P-loop; other site 272560022587 ATP binding site [chemical binding]; other site 272560022588 Q-loop/lid; other site 272560022589 ABC transporter signature motif; other site 272560022590 Walker B; other site 272560022591 D-loop; other site 272560022592 H-loop/switch region; other site 272560022593 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 169.6, E-value 3.4e-48 272560022594 PS00211 ABC transporters family signature. 272560022595 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022596 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 85.6, E-value 6.7e-23 272560022597 5 probable transmembrane helices predicted for BPSS1285 by TMHMM2.0 at aa 170-192, 207-229, 282-304, 309-328 and 409-431 272560022598 Pfam match to entry PF03412 Peptidase_C39, Peptidase C39 family , score 102.4, E-value 5.7e-28 272560022599 Signal peptide predicted for BPSS1287 by SignalP 2.0 HMM (Signal peptide probability 0.770) with cleavage site probability 0.616 between residues 20 and 21; signal peptide 272560022600 type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844 272560022601 Outer membrane efflux protein; Region: OEP; pfam02321 272560022602 Outer membrane efflux protein; Region: OEP; pfam02321 272560022603 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 91.4, E-value 1.2e-24 272560022604 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 65.1, E-value 9.9e-17 272560022605 Signal peptide predicted for BPSS1288 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 31 and 32; signal peptide 272560022606 Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405 272560022607 Pfam match to entry PF01019 G_glu_transpept, Gamma-glutamyltranspeptidase , score 644.0, E-value 5.1e-191 272560022608 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022609 PS00462 Gamma-glutamyltranspeptidase signature. 272560022610 Signal peptide predicted for BPSS1289 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.528 between residues 27 and 28; signal peptide 272560022611 Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307 272560022612 5 probable transmembrane helices predicted for BPSS1289 by TMHMM2.0 at aa 7-29, 34-56, 63-85, 95-117 and 138-160 272560022613 2 probable transmembrane helices predicted for BPSS1290 by TMHMM2.0 at aa 81-103 and 124-146 272560022614 Lhr-like helicases [General function prediction only]; Region: Lhr; COG1201 272560022615 DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046 272560022616 ATP binding site [chemical binding]; other site 272560022617 putative Mg++ binding site [ion binding]; other site 272560022618 Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079 272560022619 nucleotide binding region [chemical binding]; other site 272560022620 ATP-binding site [chemical binding]; other site 272560022621 DEAD/H associated; Region: DEAD_assoc; pfam08494 272560022622 Pfam match to entry PF00270 DEAD, DEAD/DEAH box helicase , score 111.4, E-value 1.1e-30 272560022623 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022624 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560022625 Pfam match to entry PF00271 helicase_C, Helicase conserved C-terminal domain , score 58.8, E-value 7.5e-15 272560022626 putative transporter; Provisional; Region: PRK11021 272560022627 11 probable transmembrane helices predicted for BPSS1292 by TMHMM2.0 at aa 21-43, 53-75, 95-117, 132-154, 161-183, 193-215, 236-258, 278-300, 330-352, 356-378 and 390-412 272560022628 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score -212.4, E-value 0.00011 272560022629 Signal peptide predicted for BPSS1293 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.851 between residues 24 and 25; signal peptide 272560022630 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560022631 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3795 272560022632 phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755 272560022633 Pfam match to entry PF00793 DAHP_synth_1, DAHP synthetase I family , score 490.7, E-value 7.6e-145 272560022634 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560022635 S-adenosylmethionine binding site [chemical binding]; other site 272560022636 Pfam match to entry PF01596 Methyltransf_3, O-methyltransferase , score 70.7, E-value 2.1e-18 272560022637 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560022638 metal binding site [ion binding]; metal-binding site 272560022639 active site 272560022640 I-site; other site 272560022641 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 252.2, E-value 4.8e-73 272560022642 2 probable transmembrane helices predicted for BPSS1297 by TMHMM2.0 at aa 20-42 and 298-320 272560022643 pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424 272560022644 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560022645 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560022646 dimerization interface [polypeptide binding]; other site 272560022647 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 140.4, E-value 2.1e-39 272560022648 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 94.6, E-value 1.3e-25 272560022649 PS00044 Bacterial regulatory proteins, lysR family signature. 272560022650 Predicted helix-turn-helix motif with score 1265.000, SD 3.50 at aa 25-46, sequence GSVQKAAHSLSITQPAVSKTIA 272560022651 Protocatechuate 3,4-dioxygenase (3,4-PCD) , beta subunit. 3,4-PCD catalyzes the oxidative ring cleavage of 3,4-dihydroxybenzoate to produce beta-carboxy-cis,cis-muconate. 3,4-PCDs are large aggregates of 12 protomers, each composed of an alpha- and...; Region: 3,4-PCD_beta; cd03464 272560022652 heterodimer interface [polypeptide binding]; other site 272560022653 multimer interface [polypeptide binding]; other site 272560022654 protocatechuate 3,4-dioxygenase, beta subunit; Region: protocat_beta; TIGR02422 272560022655 active site 272560022656 Pfam match to entry PF00775 Dioxygenase, Dioxygenase , score 281.5, E-value 7.1e-82 272560022657 PS00083 Intradiol ring-cleavage dioxygenases signature. 272560022658 Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. This family contains catechol 1,2-dioxygenases and protocatechuate 3,4-dioxygenases which are mononuclear...; Region: intradiol_dioxygenase; cl17208 272560022659 active site 272560022660 Pfam match to entry PF00775 Dioxygenase, Dioxygenase , score -15.9, E-value 3.7e-09 272560022661 PS00083 Intradiol ring-cleavage dioxygenases signature. 272560022662 Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_1; cd08663 272560022663 SxDxEG motif; other site 272560022664 active site 272560022665 metal binding site [ion binding]; metal-binding site 272560022666 homopentamer interface [polypeptide binding]; other site 272560022667 L-Aminopeptidase D-amidase/D-esterase (DmpA) family; DmpA catalyzes the release of N-terminal D and L amino acids from peptide susbtrates. DmpA is synthesized as a single polypeptide precursor, which is autocatalytically cleaved to the active...; Region: DmpA; cd02253 272560022668 homodimer interface [polypeptide binding]; other site 272560022669 homotetramer interface [polypeptide binding]; other site 272560022670 active site pocket [active] 272560022671 cleavage site 272560022672 Pfam match to entry PF03576 Peptidase_T4, Peptidase T4 , score 227.6, E-value 1.2e-65 272560022673 Signal peptide predicted for BPSS1304 by SignalP 2.0 HMM (Signal peptide probability 0.622) with cleavage site probability 0.420 between residues 19 and 20; signal peptide 272560022674 glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082 272560022675 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 272560022676 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560022677 dimer interface [polypeptide binding]; other site 272560022678 conserved gate region; other site 272560022679 putative PBP binding loops; other site 272560022680 ABC-ATPase subunit interface; other site 272560022681 6 probable transmembrane helices predicted for BPSS1304 by TMHMM2.0 at aa 37-59, 101-123, 136-158, 162-181, 219-241 and 266-288 272560022682 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 35.8, E-value 6.4e-08 272560022683 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560022684 glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081 272560022685 Signal peptide predicted for BPSS1305 by SignalP 2.0 HMM (Signal peptide probability 0.963) with cleavage site probability 0.377 between residues 38 and 39; signal peptide 272560022686 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560022687 dimer interface [polypeptide binding]; other site 272560022688 conserved gate region; other site 272560022689 putative PBP binding loops; other site 272560022690 ABC-ATPase subunit interface; other site 272560022691 6 probable transmembrane helices predicted for BPSS1305 by TMHMM2.0 at aa 9-31, 101-123, 135-157, 172-191, 227-249 and 277-299 272560022692 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 41.8, E-value 1e-09 272560022693 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560022694 Signal peptide predicted for BPSS1306 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.728 between residues 33 and 34; signal peptide 272560022695 ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747 272560022696 The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499 272560022697 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 237.2, E-value 1.5e-68 272560022698 glutathione transporter ATP-binding protein; Provisional; Region: PRK10261 272560022699 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560022700 Walker A/P-loop; other site 272560022701 ATP binding site [chemical binding]; other site 272560022702 Q-loop/lid; other site 272560022703 ABC transporter signature motif; other site 272560022704 Walker B; other site 272560022705 D-loop; other site 272560022706 H-loop/switch region; other site 272560022707 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352 272560022708 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560022709 Walker A/P-loop; other site 272560022710 ATP binding site [chemical binding]; other site 272560022711 Q-loop/lid; other site 272560022712 ABC transporter signature motif; other site 272560022713 Walker B; other site 272560022714 D-loop; other site 272560022715 H-loop/switch region; other site 272560022716 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560022717 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 212.6, E-value 3.9e-61 272560022718 PS00211 ABC transporters family signature. 272560022719 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022720 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 183.0, E-value 3.2e-52 272560022721 PS00211 ABC transporters family signature. 272560022722 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022723 L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701 272560022724 catalytic nucleophile [active] 272560022725 Pfam match to entry PF01112 Asparaginase_2, Asparaginase , score 347.0, E-value 1.3e-101 272560022726 Transcriptional regulators [Transcription]; Region: RpiR; COG1737 272560022727 Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418 272560022728 RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013 272560022729 putative active site [active] 272560022730 Pfam match to entry PF01380 SIS, SIS domain , score 13.0, E-value 0.0005 272560022731 Pfam match to entry PF01418 HTH_6, Helix-turn-helix domain, rpiR family , score 28.9, E-value 1.4e-07 272560022732 Signal peptide predicted for BPSS1310 by SignalP 2.0 HMM (Signal peptide probability 0.728) with cleavage site probability 0.389 between residues 43 and 44; signal peptide 272560022733 BCCT family transporter; Region: BCCT; pfam02028 272560022734 12 probable transmembrane helices predicted for BPSS1310 by TMHMM2.0 at aa 13-35, 55-77, 90-112, 143-165, 196-218, 233-250, 263-285, 317-339, 352-371, 405-427, 448-470 and 474-496 272560022735 Pfam match to entry PF02028 BCCT, BCCT family transporter , score 752.9, E-value 8.6e-224 272560022736 PS01303 BCCT family of transporters signature. 272560022737 Signal peptide predicted for BPSS1311 by SignalP 2.0 HMM (Signal peptide probability 0.945) with cleavage site probability 0.613 between residues 27 and 28; signal peptide 272560022738 Beta-lactamase; Region: Beta-lactamase; pfam00144 272560022739 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560022740 4 probable transmembrane helices predicted for BPSS1313 by TMHMM2.0 at aa 24-46, 58-80, 137-159 and 172-194 272560022741 isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743 272560022742 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 272560022743 active site 272560022744 HIGH motif; other site 272560022745 nucleotide binding site [chemical binding]; other site 272560022746 nucleotidyl transferase superfamily; Region: nt_trans; cl00015 272560022747 active site 272560022748 KMSKS motif; other site 272560022749 Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960 272560022750 tRNA binding surface [nucleotide binding]; other site 272560022751 anticodon binding site; other site 272560022752 Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827 272560022753 Pfam match to entry PF00133 tRNA-synt_1, tRNA synthetases class I (I, L, M and V) , score 613.0, E-value 1.1e-181 272560022754 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560022755 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560022756 EamA-like transporter family; Region: EamA; pfam00892 272560022757 EamA-like transporter family; Region: EamA; pfam00892 272560022758 10 probable transmembrane helices predicted for BPSS1316 by TMHMM2.0 at aa 13-35, 45-64, 76-98, 102-124, 131-148, 163-180, 187-209, 224-246, 253-275 and 280-302 272560022759 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 62.2, E-value 7.5e-16 272560022760 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 61.6, E-value 1.1e-15 272560022761 Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872 272560022762 Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; cl08469 272560022763 Pfam match to entry PF01411 tRNA-synt_2c, tRNA synthetases class II (A) , score 15.9, E-value 3.3e-05 272560022764 FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277 272560022765 FAD binding domain; Region: FAD_binding_4; pfam01565 272560022766 FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913 272560022767 Pfam match to entry PF02913 FAD-oxidase_C, FAD linked oxidases, C-terminal domain , score 267.2, E-value 1.4e-77 272560022768 Pfam match to entry PF01565 FAD_binding_4, FAD binding domain , score 222.6, E-value 3.7e-64 272560022769 Protein of unknown function (DUF1330); Region: DUF1330; cl02288 272560022770 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560022771 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560022772 S-adenosylmethionine binding site [chemical binding]; other site 272560022773 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560022774 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560022775 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560022776 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560022777 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 33.7, E-value 2.7e-07 272560022778 Predicted helix-turn-helix motif with score 1135.000, SD 3.05 at aa 194-215, sequence LTLEQIAAAAGLTSFQLITAFN 272560022779 PS00041 Bacterial regulatory proteins, araC family signature. 272560022780 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.7, E-value 1.4e-07 272560022781 Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449 272560022782 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560022783 catalytic residue [active] 272560022784 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score -6.9, E-value 1.4e-07 272560022785 leucine-responsive transcriptional regulator; Provisional; Region: PRK11169 272560022786 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560022787 putative DNA binding site [nucleotide binding]; other site 272560022788 putative Zn2+ binding site [ion binding]; other site 272560022789 AsnC family; Region: AsnC_trans_reg; pfam01037 272560022790 PS00519 Bacterial regulatory proteins, asnC family signature. 272560022791 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 107.5, E-value 1.7e-29 272560022792 PS00190 Cytochrome c family heme-binding site signature. 272560022793 LabA_like proteins; Region: LabA_like; cd06167 272560022794 putative metal binding site [ion binding]; other site 272560022795 Uncharacterized conserved protein [Function unknown]; Region: COG1432 272560022796 C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146 272560022797 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560022798 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022799 putative substrate translocation pore; other site 272560022800 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -97.0, E-value 0.0002 272560022801 12 probable transmembrane helices predicted for BPSS1327 by TMHMM2.0 at aa 35-52, 67-89, 102-124, 129-151, 163-185, 195-217, 263-285, 300-318, 325-347, 352-374, 379-401 and 416-438 272560022802 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 272560022803 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560022804 DNA-binding site [nucleotide binding]; DNA binding site 272560022805 UTRA domain; Region: UTRA; pfam07702 272560022806 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 72.5, E-value 5.8e-19 272560022807 benzoate transport; Region: 2A0115; TIGR00895 272560022808 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022809 putative substrate translocation pore; other site 272560022810 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 58.2, E-value 1.1e-14 272560022811 10 probable transmembrane helices predicted for BPSS1329 by TMHMM2.0 at aa 36-58, 68-90, 103-125, 186-205, 261-283, 298-320, 327-349, 353-375, 388-410 and 415-437 272560022812 PS00217 Sugar transport proteins signature 2. 272560022813 PS00216 Sugar transport proteins signature 1. 272560022814 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560022815 active site 272560022816 Signal peptide predicted for BPSS1331 by SignalP 2.0 HMM (Signal peptide probability 0.806) with cleavage site probability 0.708 between residues 47 and 48; signal peptide 272560022817 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 272560022818 active site 272560022819 metal binding site [ion binding]; metal-binding site 272560022820 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560022821 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 59.5, E-value 4.8e-15 272560022822 PS00125 Serine/threonine specific protein phosphatases signature. 272560022823 Signal peptide predicted for BPSS1332 by SignalP 2.0 HMM (Signal peptide probability 0.862) with cleavage site probability 0.830 between residues 34 and 35; signal peptide 272560022824 Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150 272560022825 di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039 272560022826 1 probable transmembrane helix predicted for BPSS1332 by TMHMM2.0 at aa 49-71 272560022827 Pfam match to entry PF03150 CCP_MauG, Di-haem cytochrome c peroxidase , score 35.8, E-value 5.1e-13 272560022828 PS00190 Cytochrome c family heme-binding site signature. 272560022829 PS00190 Cytochrome c family heme-binding site signature. 272560022830 Leucine carboxyl methyltransferase; Region: LCM; pfam04072 272560022831 Protein of unknown function (DUF3079); Region: DUF3079; pfam11278 272560022832 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560022833 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560022834 Coenzyme A binding pocket [chemical binding]; other site 272560022835 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 72.7, E-value 5.2e-19 272560022836 Predicted transporter component [General function prediction only]; Region: COG2391 272560022837 Sulphur transport; Region: Sulf_transp; pfam04143 272560022838 4 probable transmembrane helices predicted for BPSS1337 by TMHMM2.0 at aa 2-20, 35-57, 81-103 and 113-130 272560022839 Domain of unknown function (DUF4341); Region: DUF4341; pfam14241 272560022840 Predicted transporter component [General function prediction only]; Region: COG2391 272560022841 4 probable transmembrane helices predicted for BPSS1338 by TMHMM2.0 at aa 10-32, 52-74, 84-103 and 116-138 272560022842 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560022843 dimerization interface [polypeptide binding]; other site 272560022844 putative DNA binding site [nucleotide binding]; other site 272560022845 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560022846 putative Zn2+ binding site [ion binding]; other site 272560022847 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 85.1, E-value 9.5e-23 272560022848 Predicted helix-turn-helix motif with score 1089.000, SD 2.90 at aa 36-57, sequence LCVSDIEARLDIHQPTLSQQLG 272560022849 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 272560022850 4 probable transmembrane helices predicted for BPSS1340 by TMHMM2.0 at aa 13-35, 50-72, 84-106 and 145-167 272560022851 Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453 272560022852 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560022853 catalytic residue [active] 272560022854 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 70.7, E-value 2e-18 272560022855 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560022856 non-specific DNA binding site [nucleotide binding]; other site 272560022857 salt bridge; other site 272560022858 sequence-specific DNA binding site [nucleotide binding]; other site 272560022859 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 64.3, E-value 1.7e-16 272560022860 Predicted helix-turn-helix motif with score 1705.000, SD 4.99 at aa 21-42, sequence WSQEQLAEHAGLNRSYVGEIER 272560022861 serine O-acetyltransferase; Region: cysE; TIGR01172 272560022862 Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354 272560022863 trimer interface [polypeptide binding]; other site 272560022864 active site 272560022865 substrate binding site [chemical binding]; other site 272560022866 CoA binding site [chemical binding]; other site 272560022867 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 11.2, E-value 1.6 272560022868 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 7.1, E-value 5.9 272560022869 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 14.5, E-value 0.17 272560022870 Pfam match to entry PF00132 hexapep, Bacterial transferase hexapeptide (four repeats) , score 0.2, E-value 45 272560022871 Member of the Rhodanese Homology Domain superfamily, subgroup 1. This CD includes the putative rhodanese-related sulfurtransferases of several uncharacterized proteins; Region: RHOD_1; cd01522 272560022872 active site residue [active] 272560022873 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 47.1, E-value 2.6e-11 272560022874 Serine proteases of the peptidase family S9A [Amino acid transport and metabolism]; Region: COG1505 272560022875 Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326 272560022876 Pfam match to entry PF02897 Peptidase_S9_N, Prolyl oligopeptidase, N-terminal beta-propeller domain , score -34.8, E-value 2.9e-11 272560022877 Pfam match to entry PF00326 Peptidase_S9, Prolyl oligopeptidase , score 79.9, E-value 3.3e-21 272560022878 multidrug efflux system protein EmrA; Provisional; Region: PRK15136 272560022879 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560022880 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560022881 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 195.9, E-value 4e-56 272560022882 1 probable transmembrane helix predicted for BPSS1347 by TMHMM2.0 at aa 51-73 272560022883 Signal peptide predicted for BPSS1348 by SignalP 2.0 HMM (Signal peptide probability 0.775) with cleavage site probability 0.489 between residues 41 and 42; signal peptide 272560022884 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560022885 Outer membrane efflux protein; Region: OEP; pfam02321 272560022886 Outer membrane efflux protein; Region: OEP; pfam02321 272560022887 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 118.9, E-value 6.4e-33 272560022888 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 53.9, E-value 2.4e-13 272560022889 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560022890 RfbF is a putative dTDP-rhamnosyl transferase; Region: GT2_RfbF_like; cd02526 272560022891 L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556 272560022892 Ligand binding site; other site 272560022893 drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711 272560022894 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022895 putative substrate translocation pore; other site 272560022896 14 probable transmembrane helices predicted for BPSS1350 by TMHMM2.0 at aa 34-56, 71-93, 100-119, 124-146, 159-181, 186-208, 215-237, 247-269, 289-311, 326-348, 355-377, 387-409, 422-439 and 498-515 272560022897 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -116.9, E-value 0.00097 272560022898 Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819 272560022899 This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784 272560022900 active site 272560022901 TDP-binding site; other site 272560022902 acceptor substrate-binding pocket; other site 272560022903 homodimer interface [polypeptide binding]; other site 272560022904 Pfam match to entry PF00201 UDPGT, UDP-glucoronosyl and UDP-glucosyl transferase , score 18.3, E-value 1.6e-05 272560022905 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560022906 transcriptional regulator BetI; Validated; Region: PRK00767 272560022907 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560022908 Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977 272560022909 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 51.3, E-value 1.4e-12 272560022910 PS01081 Bacterial regulatory proteins, tetR family signature. 272560022911 Predicted helix-turn-helix motif with score 1629.000, SD 4.74 at aa 37-58, sequence TTLASVAQRANISTGIVSHYFG 272560022912 NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090 272560022913 tetrameric interface [polypeptide binding]; other site 272560022914 NAD binding site [chemical binding]; other site 272560022915 catalytic residues [active] 272560022916 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 802.8, E-value 8.4e-239 272560022917 PS00017 ATP/GTP-binding site motif A (P-loop). 272560022918 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560022919 PS00070 Aldehyde dehydrogenases cysteine active site. 272560022920 choline dehydrogenase; Validated; Region: PRK02106 272560022921 GMC oxidoreductase; Region: GMC_oxred_N; pfam00732 272560022922 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560022923 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score 924.8, E-value 1.6e-275 272560022924 PS00623 GMC oxidoreductases signature 1. 272560022925 PS00052 Ribosomal protein S7 signature. 272560022926 PS00624 GMC oxidoreductases signature 2. 272560022927 Prokaryotic protein of unknown function (DUF849); Region: DUF849; cl15827 272560022928 PS00037 Myb DNA-binding domain repeat signature 1. 272560022929 benzoate transport; Region: 2A0115; TIGR00895 272560022930 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560022931 putative substrate translocation pore; other site 272560022932 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 190.5, E-value 1.7e-54 272560022933 10 probable transmembrane helices predicted for BPSS1357 by TMHMM2.0 at aa 9-31, 46-68, 134-156, 160-179, 252-274, 284-306, 313-335, 339-361, 382-401 and 405-427 272560022934 PS00216 Sugar transport proteins signature 1. 272560022935 PS00217 Sugar transport proteins signature 2. 272560022936 PS00216 Sugar transport proteins signature 1. 272560022937 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560022938 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560022939 active site 272560022940 phosphorylation site [posttranslational modification] 272560022941 intermolecular recognition site; other site 272560022942 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560022943 PAS fold; Region: PAS_3; pfam08447 272560022944 putative active site [active] 272560022945 heme pocket [chemical binding]; other site 272560022946 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920 272560022947 Histidine kinase; Region: HisKA_3; pfam07730 272560022948 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560022949 ATP binding site [chemical binding]; other site 272560022950 Mg2+ binding site [ion binding]; other site 272560022951 G-X-G motif; other site 272560022952 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 77.1, E-value 2.4e-20 272560022953 Pfam match to entry PF00785 PAC, PAC motif , score 44.0, E-value 2.1e-10 272560022954 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 59.6, E-value 4.5e-15 272560022955 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560022956 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560022957 active site 272560022958 phosphorylation site [posttranslational modification] 272560022959 intermolecular recognition site; other site 272560022960 dimerization interface [polypeptide binding]; other site 272560022961 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 53.2, E-value 3.7e-13 272560022962 CHASE3 domain; Region: CHASE3; pfam05227 272560022963 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560022964 PAS domain; Region: PAS_9; pfam13426 272560022965 putative active site [active] 272560022966 heme pocket [chemical binding]; other site 272560022967 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 272560022968 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560022969 putative active site [active] 272560022970 heme pocket [chemical binding]; other site 272560022971 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560022972 dimer interface [polypeptide binding]; other site 272560022973 phosphorylation site [posttranslational modification] 272560022974 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560022975 ATP binding site [chemical binding]; other site 272560022976 Mg2+ binding site [ion binding]; other site 272560022977 G-X-G motif; other site 272560022978 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 146.6, E-value 2.8e-41 272560022979 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 49.5, E-value 5e-12 272560022980 Pfam match to entry PF00785 PAC, PAC motif , score 16.2, E-value 0.048 272560022981 Pfam match to entry PF00989 PAS, PAS domain , score 39.5, E-value 4.9e-09 272560022982 Pfam match to entry PF00785 PAC, PAC motif , score 34.2, E-value 1.9e-07 272560022983 Pfam match to entry PF00989 PAS, PAS domain , score 33.7, E-value 2.7e-07 272560022984 2 probable transmembrane helices predicted for BPSS1360 by TMHMM2.0 at aa 32-54 and 202-224 272560022985 OsmC-like protein; Region: OsmC; cl00767 272560022986 Pfam match to entry PF02566 OsmC, OsmC-like protein , score 48.5, E-value 9.4e-12 272560022987 Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052 272560022988 Hydroxy(phenyl)pyruvate Reductase, D-isomer-specific 2-hydroxyacid-related dehydrogenase; Region: HPPR; cd12156 272560022989 putative ligand binding site [chemical binding]; other site 272560022990 NAD binding site [chemical binding]; other site 272560022991 catalytic site [active] 272560022992 Pfam match to entry PF02826 2-Hacid_DH_C, D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain , score 154.2, E-value 1.5e-43 272560022993 PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 272560022994 Pfam match to entry PF00389 2-Hacid_DH, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain , score 37.3, E-value 2.3e-08 272560022995 Signal peptide predicted for BPSS1363 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.869 between residues 24 and 25; signal peptide 272560022996 Protein of unknown function (DUF3761); Region: DUF3761; pfam12587 272560022997 Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458 272560022998 DNA-binding site [nucleotide binding]; DNA binding site 272560022999 RNA-binding motif; other site 272560023000 Pfam match to entry PF00313 CSD, 'Cold-shock' DNA-binding domain , score 133.7, E-value 2.2e-37 272560023001 PS00352 'Cold-shock' DNA-binding domain signature. 272560023002 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 272560023003 Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539 272560023004 active site 272560023005 Pfam match to entry PF02152 FolB, Dihydroneopterin aldolase , score 27.5, E-value 4.2e-06 272560023006 Sarcosine oxidase gamma subunit [Amino acid transport and metabolism]; Region: COG4583 272560023007 sarcosine oxidase, alpha subunit family, heterotetrameric form; Region: soxA; TIGR01372 272560023008 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_4; pfam13510 272560023009 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560023010 Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571 272560023011 Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669 272560023012 Pfam match to entry PF01571 GCV_T, Glycine cleavage T-protein (aminomethyl transferase) , score 307.7, E-value 9.3e-90 272560023013 Sarcosine oxidase delta subunit [Amino acid transport and metabolism]; Region: SoxD; COG4311 272560023014 sarcosine oxidase, beta subunit family, heterotetrameric form; Region: soxB; TIGR01373 272560023015 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560023016 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -64.3, E-value 0.00015 272560023017 L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720 272560023018 Serine dehydratase beta chain; Region: SDH_beta; pfam03315 272560023019 Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313 272560023020 Pfam match to entry PF03313 SDH_alpha, Serine dehydratase alpha chain , score 565.0, E-value 3.2e-167 272560023021 PS00159 KDPG and KHG aldolases active site. 272560023022 Pfam match to entry PF03315 SDH_beta, Serine dehydratase beta chain , score 197.7, E-value 1.2e-56 272560023023 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560023024 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 272560023025 conserved cys residue [active] 272560023026 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023027 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023028 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 25.7, E-value 1.2e-05 272560023029 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 35.8, E-value 6.6e-08 272560023030 Predicted helix-turn-helix motif with score 1623.000, SD 4.71 at aa 251-272, sequence LPLDELACKLDLSTRQLERLFK 272560023031 PS00041 Bacterial regulatory proteins, araC family signature. 272560023032 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 43.6, E-value 2.9e-10 272560023033 Protein of unknown function, DUF480; Region: DUF480; pfam04337 272560023034 Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388 272560023035 C-terminal, alpha helical domain of Class Sigma-like Glutathione S-transferases; Region: GST_C_Sigma_like; cd03192 272560023036 dimer interface [polypeptide binding]; other site 272560023037 N-terminal domain interface [polypeptide binding]; other site 272560023038 substrate binding pocket (H-site) [chemical binding]; other site 272560023039 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 16.7, E-value 0.00013 272560023040 Low affinity iron permease; Region: Iron_permease; pfam04120 272560023041 2 probable transmembrane helices predicted for BPSS1375 by TMHMM2.0 at aa 39-61 and 71-90 272560023042 Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294 272560023043 Cytochrome oxidase subunit II; Region: Cyto_ox_2; pfam02322 272560023044 Pfam match to entry PF02322 Cyto_ox_2, Cytochrome oxidase subunit II , score 377.0, E-value 1.3e-110 272560023045 8 probable transmembrane helices predicted for BPSS1376 by TMHMM2.0 at aa 5-23, 74-96, 116-138, 158-180, 192-214, 224-246, 259-281 and 301-323 272560023046 Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654 272560023047 Pfam match to entry PF01654 Bac_Ubq_Cox, Bacterial Cytochrome Ubiquinol Oxidase , score 522.9, E-value 1.5e-154 272560023048 9 probable transmembrane helices predicted for BPSS1377 by TMHMM2.0 at aa 13-35, 55-77, 97-119, 126-148, 187-209, 216-238, 322-344, 356-378 and 407-429 272560023049 Domain of unknown function (DUF305); Region: DUF305; cl17794 272560023050 Pfam match to entry PF03713 DUF305, Domain of unknown function , score 76.7, E-value 3.1e-20 272560023051 1 probable transmembrane helix predicted for BPSS1378 by TMHMM2.0 at aa 17-36 272560023052 Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285 272560023053 MgtC family; Region: MgtC; pfam02308 272560023054 4 probable transmembrane helices predicted for BPSS1379 by TMHMM2.0 at aa 34-56, 68-90, 105-123 and 136-167 272560023055 Pfam match to entry PF02308 MgtC, MgtC family , score 179.7, E-value 3e-51 272560023056 Catalytic domain, repeat 1, of uncharacterized bacterial proteins with similarity to vertebrate phospholipases, PLD1 and PLD2; Region: PLDc_vPLD1_2_like_bac_1; cd09140 272560023057 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 272560023058 putative active site [active] 272560023059 catalytic site [active] 272560023060 Catalytic domain, repeat 2, of uncharacterized bacterial proteins with similarity to vertebrate phospholipases, PLD1 and PLD2; Region: PLDc_vPLD1_2_like_bac_2; cd09143 272560023061 putative active site [active] 272560023062 catalytic site [active] 272560023063 Uncharacterized conserved protein [Function unknown]; Region: COG0398 272560023064 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 38.4, E-value 1e-08 272560023065 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 27.7, E-value 1.7e-05 272560023066 5 probable transmembrane helices predicted for BPSS1381 by TMHMM2.0 at aa 513-535, 556-578, 588-610, 669-691 and 701-723 272560023067 Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490 272560023068 putative catalytic site [active] 272560023069 putative metal binding site [ion binding]; other site 272560023070 putative phosphate binding site [ion binding]; other site 272560023071 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 71.2, E-value 1.4e-18 272560023072 PPIC-type PPIASE domain; Region: Rotamase; pfam00639 272560023073 2 probable transmembrane helices predicted for BPSS1384 by TMHMM2.0 at aa 192-214 and 235-257 272560023074 Probable gene remnant. Similar to the C-terminal regions of Escherichia coli transposase for transposon Tn1721 TnpA SWALL:TNP9_ECOLI (SWALL:P51565) (988 aa) fasta scores: E(): 6.2e-13, 48.71% id in 117 aa, and Pseudomonas aeruginosa transposase for transposon Tn501 TnpA SWALL:TNP5_PSEAE (SWALL:P06695) (988 aa) fasta scores: E(): 6.2e-13, 48.71% id in 117 aa;transposase (fragment) 272560023075 capsular exopolysaccharide family; Region: eps_fam; TIGR01007 272560023076 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023077 Probable gene remnant. Similar to internal regions of Burkholderia cepacia transposase for insertion sequence element IS402 SWALL:T402_BURCE (SWALL:P24536) (211 aa) fasta scores: E(): 1.4e-05, 37.63% id in 93 aa, and to Alcaligenes eutrophus ISJp4 transposase TnpA SWALL:Q6UP96 (EMBL:AY365053) (262 aa) fasta scores: E(): 0.00013, 33.7% id in 89 aa;transposase (fragment) 272560023078 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023079 PS00019 Actinin-type actin-binding domain signature 1. 272560023080 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560023081 Predicted membrane protein [Function unknown]; Region: COG1511 272560023082 1 probable transmembrane helix predicted for BPSS1388 by TMHMM2.0 at aa 551-573 272560023083 Signal peptide predicted for BPSS1390 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.974 between residues 26 and 27; signal peptide 272560023084 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 272560023085 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023086 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023087 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560023088 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 277.0, E-value 1.5e-80 272560023089 PS00875 Bacterial type II secretion system protein D signature. 272560023090 PS00044 Bacterial regulatory proteins, lysR family signature. 272560023091 Pfam match to entry PF03958 NolW-like, NolW-like , score 219.0, E-value 4.4e-63 272560023092 1 probable transmembrane helix predicted for BPSS1390 by TMHMM2.0 at aa 7-29 272560023093 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023094 Helix-turn-helix domain; Region: HTH_18; pfam12833 272560023095 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 15.4, E-value 0.057 272560023096 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 40.4, E-value 2.6e-09 272560023097 Predicted helix-turn-helix motif with score 1597.000, SD 4.63 at aa 395-416, sequence LSVREIAAEIGVTERALQNAFK 272560023098 Bacterial export proteins, family 1; Region: Bac_export_1; cl00734 272560023099 Pfam match to entry PF01311 Bac_export_1, Bacterial export proteins, family 1 , score 194.2, E-value 1.3e-55 272560023100 5 probable transmembrane helices predicted for BPSS1392 by TMHMM2.0 at aa 10-32, 87-109, 135-157, 195-214 and 224-246 272560023101 type III secretion protein HrpB7; Region: HrpB7; TIGR02559 272560023102 type III secretion system ATPase; Provisional; Region: PRK09099 272560023103 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560023104 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560023105 Walker A motif; other site 272560023106 ATP binding site [chemical binding]; other site 272560023107 Walker B motif; other site 272560023108 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 482.1, E-value 2.9e-142 272560023109 PS00152 ATP synthase alpha and beta subunits signature. 272560023110 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023111 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 36.6, E-value 3.8e-08 272560023112 type III secretion system protein HrpB; Validated; Region: PRK09098 272560023113 Flagellar assembly protein FliH; Region: FliH; cl19405 272560023114 type III secretion protein HrpB4; Region: HrpB4; TIGR02560 272560023115 type III secretion apparatus lipoprotein, YscJ/HrcJ family; Region: III_secr_YscJ; TIGR02544 272560023116 1 probable transmembrane helix predicted for BPSS1397 by TMHMM2.0 at aa 216-238 272560023117 Pfam match to entry PF01514 YscJ_FliF, Secretory protein of YscJ/FliF family , score 298.0, E-value 7.4e-87 272560023118 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560023119 type III secretion protein HrpB2; Region: HrpB2; TIGR02558 272560023120 type III secretion protein HrpB1/HrpK; Region: HrpB1_HrpK; TIGR02561 272560023121 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560023122 TPR motif; other site 272560023123 TPR repeat; Region: TPR_11; pfam13414 272560023124 binding surface 272560023125 type III secretion system protein HrcU; Validated; Region: PRK09108 272560023126 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family , score 418.9, E-value 3.1e-123 272560023127 3 probable transmembrane helices predicted for BPSS1400 by TMHMM2.0 at aa 83-105, 148-170 and 180-202 272560023128 FHIPEP family; Region: FHIPEP; cl07980 272560023129 7 probable transmembrane helices predicted for BPSS1401 by TMHMM2.0 at aa 7-29, 33-55, 62-84, 104-126, 196-218, 233-255 and 288-310 272560023130 Pfam match to entry PF00771 FHIPEP, FHIPEP family , score 1005.6, E-value 7.6e-300 272560023131 PS00994 Bacterial export FHIPEP family signature. 272560023132 type III secretion protein HpaP; Region: HpaP; TIGR02557 272560023133 type III secretion system apparatus protein YscQ/HrcQ; Region: SpaO_YscQ; TIGR02551 272560023134 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 272560023135 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein , score 98.1, E-value 1.1e-26 272560023136 type III secretion system protein YscR; Provisional; Region: PRK12797 272560023137 Signal peptide predicted for BPSS1404 by SignalP 2.0 HMM (Signal peptide probability 0.972) with cleavage site probability 0.530 between residues 31 and 32; signal peptide 272560023138 4 probable transmembrane helices predicted for BPSS1404 by TMHMM2.0 at aa 7-29, 44-66, 157-179 and 189-211 272560023139 Pfam match to entry PF00813 FliP, FliP family , score 359.4, E-value 2.5e-105 272560023140 PS00043 Bacterial regulatory proteins, gntR family signature. 272560023141 PS01060 Flagella transport protein fliP family signature 1. 272560023142 PS01061 Flagella transport protein fliP family signature 2. 272560023143 Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794 272560023144 Signal peptide predicted for BPSS1405 by SignalP 2.0 HMM (Signal peptide probability 0.688) with cleavage site probability 0.437 between residues 28 and 29; signal peptide 272560023145 Pfam match to entry PF01313 Bac_export_3, Bacterial export proteins, family 3 , score 106.2, E-value 4.1e-29 272560023146 2 probable transmembrane helices predicted for BPSS1405 by TMHMM2.0 at aa 13-35 and 55-77 272560023147 type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500 272560023148 Tir chaperone protein (CesT) family; Region: CesT; cl08444 272560023149 Cupin domain; Region: Cupin_2; cl17218 272560023150 Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419 272560023151 ?-D-glucose-1-phosphatase; Provisional; Region: PRK09456 272560023152 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 39.6, E-value 4.6e-09 272560023153 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560023154 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560023155 DNA-binding site [nucleotide binding]; DNA binding site 272560023156 FCD domain; Region: FCD; pfam07729 272560023157 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 72.9, E-value 4.3e-19 272560023158 PS00043 Bacterial regulatory proteins, gntR family signature. 272560023159 Predicted helix-turn-helix motif with score 1129.000, SD 3.03 at aa 34-55, sequence PTEAVLAQEFGVSRTVIREAIS 272560023160 Signal peptide predicted for BPSS1415 by SignalP 2.0 HMM (Signal peptide probability 0.853) with cleavage site probability 0.395 between residues 30 and 31; signal peptide 272560023161 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560023162 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 272560023163 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560023164 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score -90.8, E-value 0.0072 272560023165 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395 272560023166 putative aldolase; Validated; Region: PRK08130 272560023167 intersubunit interface [polypeptide binding]; other site 272560023168 active site 272560023169 Zn2+ binding site [ion binding]; other site 272560023170 Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain , score 148.0, E-value 1.1e-41 272560023171 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 272560023172 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560023173 putative substrate translocation pore; other site 272560023174 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -57.1, E-value 8.1e-06 272560023175 12 probable transmembrane helices predicted for BPSS1418 by TMHMM2.0 at aa 32-51, 66-88, 101-120, 126-148, 160-182, 195-217, 263-285, 295-317, 330-347, 351-373, 380-402 and 417-439 272560023176 Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622 272560023177 Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181 272560023178 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560023179 Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs; Region: Gne_like_SDR_e; cd05238 272560023180 putative NAD(P) binding site [chemical binding]; other site 272560023181 active site 272560023182 putative substrate binding site [chemical binding]; other site 272560023183 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555 272560023184 Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases [Posttranslational modification, protein turnover, chaperones]; Region: COG3555 272560023185 1 probable transmembrane helix predicted for BPSS1422 by TMHMM2.0 at aa 295-314 272560023186 choline ABC transporter, periplasmic binding protein; Region: ABC_choline_bnd; TIGR03414 272560023187 Signal peptide predicted for BPSS1424 by SignalP 2.0 HMM (Signal peptide probability 0.858) with cleavage site probability 0.515 between residues 20 and 21; signal peptide 272560023188 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560023189 AraC transcriptional regulators having an N-terminal Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_ArgR_like; cd03136 272560023190 conserved cys residue [active] 272560023191 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023192 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.1, E-value 2.1e-07 272560023193 PS00041 Bacterial regulatory proteins, araC family signature. 272560023194 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 39.6, E-value 4.5e-09 272560023195 Predicted helix-turn-helix motif with score 1808.000, SD 5.34 at aa 245-266, sequence LSLEELARLVRLSQRHLQRMFK 272560023196 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 32.7, E-value 5.6e-07 272560023197 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 272560023198 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560023199 dimer interface [polypeptide binding]; other site 272560023200 conserved gate region; other site 272560023201 putative PBP binding loops; other site 272560023202 ABC-ATPase subunit interface; other site 272560023203 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 44.4, E-value 1.7e-10 272560023204 5 probable transmembrane helices predicted for BPSS1425 by TMHMM2.0 at aa 44-66, 68-85, 90-112, 132-154 and 213-235 272560023205 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560023206 ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175 272560023207 ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294 272560023208 Walker A/P-loop; other site 272560023209 ATP binding site [chemical binding]; other site 272560023210 Q-loop/lid; other site 272560023211 ABC transporter signature motif; other site 272560023212 Walker B; other site 272560023213 D-loop; other site 272560023214 H-loop/switch region; other site 272560023215 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354 272560023216 Pfam match to entry PF00571 CBS, CBS domain , score 25.3, E-value 9.6e-05 272560023217 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 216.2, E-value 3.1e-62 272560023218 PS00211 ABC transporters family signature. 272560023219 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023220 NADPH-dependent FMN reductase; Region: FMN_red; pfam03358 272560023221 Pfam match to entry PF03358 FMN_red, NADPH-dependent FMN reductase , score 38.7, E-value 8.5e-09 272560023222 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560023223 dimerization interface [polypeptide binding]; other site 272560023224 putative DNA binding site [nucleotide binding]; other site 272560023225 putative Zn2+ binding site [ion binding]; other site 272560023226 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 30.3, E-value 2.9e-06 272560023227 Predicted helix-turn-helix motif with score 1218.000, SD 3.34 at aa 33-54, sequence LPAGRIAALLDVPPSSLSFHLK 272560023228 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_20; cd07254 272560023229 putative metal binding site [ion binding]; other site 272560023230 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 11.1, E-value 0.0047 272560023231 Low molecular weight phosphatase family; Region: LMWPc; cd00115 272560023232 active site 272560023233 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase , score 88.3, E-value 1e-23 272560023234 Sodium Bile acid symporter family; Region: SBF; cl19217 272560023235 10 probable transmembrane helices predicted for BPSS1433 by TMHMM2.0 at aa 20-42, 57-75, 96-115, 130-152, 165-187, 191-213, 233-252, 262-284, 297-319 and 324-346 272560023236 Pfam match to entry PF01758 SBF, Sodium Bile acid symporter family , score 104.3, E-value 1.5e-28 272560023237 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560023238 Left-handed beta-roll, including virulence factors and various other proteins; Region: LbR-like; cl17507 272560023239 trimer interface [polypeptide binding]; other site 272560023240 Autotransporter adhesin [Intracellular trafficking and secretion / Extracellular structures]; Region: Hia; COG5295 272560023241 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560023242 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560023243 Signal peptide predicted for BPSS1437 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.730 between residues 31 and 32; signal peptide 272560023244 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560023245 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560023246 binding surface 272560023247 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560023248 Pfam match to entry PF00515 TPR, TPR Domain , score 8.9, E-value 0.33 272560023249 Pfam match to entry PF00515 TPR, TPR Domain , score 1.4, E-value 2.1 272560023250 Pfam match to entry PF00515 TPR, TPR Domain , score 25.6, E-value 7.8e-05 272560023251 Pfam match to entry PF00515 TPR, TPR Domain , score 16.9, E-value 0.031 272560023252 Pfam match to entry PF00515 TPR, TPR Domain , score 10.2, E-value 0.24 272560023253 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023254 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560023255 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560023256 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560023257 Pfam match to entry PF03895 YadA, YadA-like C-terminal region , score 41.0, E-value 1.8e-09 272560023258 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 272560023259 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 272560023260 Protein of unknown function (DUF2827); Region: DUF2827; pfam10933 272560023261 Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770 272560023262 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560023263 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560023264 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878 272560023265 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 272560023266 carboxyltransferase (CT) interaction site; other site 272560023267 biotinylation site [posttranslational modification]; other site 272560023268 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 80.8, E-value 1.8e-21 272560023269 PS00188 Biotin-requiring enzymes attachment site. 272560023270 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain , score 173.8, E-value 1.9e-49 272560023271 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 359.0, E-value 3.2e-105 272560023272 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560023273 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560023274 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 178.8, E-value 5.6e-51 272560023275 PS00296 Chaperonins cpn60 signature. 272560023276 enoyl-CoA hydratase; Provisional; Region: PRK05995 272560023277 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560023278 substrate binding site [chemical binding]; other site 272560023279 oxyanion hole (OAH) forming residues; other site 272560023280 trimer interface [polypeptide binding]; other site 272560023281 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 128.0, E-value 1.2e-35 272560023282 3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820 272560023283 malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682 272560023284 Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain , score 716.9, E-value 6.1e-213 272560023285 isovaleryl-CoA dehydrogenase; Region: PLN02519 272560023286 Isovaleryl-CoA dehydrogenase; Region: IVD; cd01156 272560023287 substrate binding site [chemical binding]; other site 272560023288 FAD binding site [chemical binding]; other site 272560023289 catalytic base [active] 272560023290 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 208.9, E-value 5e-60 272560023291 PS00073 Acyl-CoA dehydrogenases signature 2. 272560023292 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 200.9, E-value 1.3e-57 272560023293 PS00072 Acyl-CoA dehydrogenases signature 1. 272560023294 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 177.9, E-value 1.1e-50 272560023295 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560023296 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560023297 YsiA-like protein, C-terminal region; Region: TetR_C_4; pfam08359 272560023298 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 65.6, E-value 7e-17 272560023299 Predicted helix-turn-helix motif with score 1804.000, SD 5.33 at aa 20-41, sequence ATAAEIAQRVGVSEATVFSYFR 272560023300 Probable gene remnant. Similar to the C-terminal regions of Bordetella pertussis hypothetical protein SWALL:Q7VSI5 (EMBL:BX640412) (134 aa) fasta scores: E(): 5.8e-16, 66.26% id in 83 aa, and to Bordetella parapertussis hypothetical protein SWALL:Q7WC61 (EMBL:BX640424) (134 aa) fasta scores: E(): 5.8e-16, 67.47% id in 83 aa;conserved hypothetical protein (fragment) 272560023301 Similar to Alcaligenes eutrophus nitric oxide reductase NorZ SWALL:O30375 (EMBL:AF002661) (762 aa) fasta scores: E(): 2.7e-60, 35% id in 757 aa, and to Alcaligenes eutrophus nitric oxide reductase SWALL:O30368 (EMBL:AF002217) (762 aa) fasta scores: E(): 6.7e-52, 34.93% id in 770 aa. CDS contains a frameshift mutation after codon 222; nitric oxide reductase (pseudogene) 272560023302 1 probable transmembrane helix predicted for BPSS1450 by TMHMM2.0 at aa 39-61 272560023303 13 probable transmembrane helices predicted for BPSS1451 by TMHMM2.0 at aa 10-32, 60-82, 108-130, 143-165, 185-207, 230-252, 277-294, 301-323, 328-350, 371-393, 408-430, 450-472 and 509-531 272560023304 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560023305 Cupredoxin domain 1 of Copper-containing nitrite reductase; Region: CuRO_1_CuNIR; cd11020 272560023306 Type 1 (T1) Cu binding site [ion binding]; other site 272560023307 trimer interface [polypeptide binding]; other site 272560023308 Type II Cu binding site [ion binding]; other site 272560023309 Cupredoxin domain 2 of Copper-containing nitrite reductase; Region: CuRO_2_CuNIR; cd04208 272560023310 trimer interface [polypeptide binding]; other site 272560023311 Cu binding site [ion binding]; other site 272560023312 Cytochrome c; Region: Cytochrom_C; cl11414 272560023313 Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase , score 4.5, E-value 0.0028 272560023314 PS00190 Cytochrome c family heme-binding site signature. 272560023315 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 272560023316 [2Fe-2S] cluster binding site [ion binding]; other site 272560023317 Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938 272560023318 C-terminal catalytic domain of the oxygenase alpha subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C; cd00680 272560023319 alpha subunit interface [polypeptide binding]; other site 272560023320 active site 272560023321 substrate binding site [chemical binding]; other site 272560023322 Fe binding site [ion binding]; other site 272560023323 carboxynorspermidine decarboxylase; Region: nspC; TIGR01047 272560023324 Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829 272560023325 dimer interface [polypeptide binding]; other site 272560023326 active site 272560023327 pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site 272560023328 catalytic residues [active] 272560023329 substrate binding site [chemical binding]; other site 272560023330 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 81.3, E-value 1.3e-21 272560023331 Pfam match to entry PF02784 Orn_Arg_deC_N, Pyridoxal-dependent decarboxylase, pyridoxal binding domain , score -59.9, E-value 2.3e-05 272560023332 Pfam match to entry PF00278 Orn_DAP_Arg_deC, Pyridoxal-dependent decarboxylase, C-terminal sheet domain , score -9.4, E-value 3.6e-05 272560023333 Protein of unknown function (DUF3326); Region: DUF3326; pfam11805 272560023334 Cupin-like domain; Region: Cupin_8; cl19305 272560023335 Pfam match to entry PF02373 jmjC, jmjC domain , score 53.1, E-value 3.9e-13 272560023336 Signal peptide predicted for BPSS1456 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.710 between residues 23 and 24; signal peptide 272560023337 Protein of unknown function (DUF2891); Region: DUF2891; pfam11199 272560023338 benzoate transport; Region: 2A0115; TIGR00895 272560023339 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560023340 putative substrate translocation pore; other site 272560023341 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 118.0, E-value 1.2e-32 272560023342 12 probable transmembrane helices predicted for BPSS1458 by TMHMM2.0 at aa 27-49, 71-93, 100-118, 128-147, 160-182, 192-209, 279-301, 311-332, 339-358, 363-385, 398-420 and 424-446 272560023343 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 272560023344 PS00217 Sugar transport proteins signature 2. 272560023345 PS01159 WW/rsp5/WWP domain signature. 272560023346 Signal peptide predicted for BPSS1459 by SignalP 2.0 HMM (Signal peptide probability 0.753) with cleavage site probability 0.440 between residues 23 and 24; signal peptide 272560023347 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560023348 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560023349 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560023350 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 28.9, E-value 7.8e-06 272560023351 Signal peptide predicted for BPSS1460 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.395 between residues 26 and 27; signal peptide 272560023352 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560023353 HAMP domain; Region: HAMP; pfam00672 272560023354 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560023355 dimer interface [polypeptide binding]; other site 272560023356 phosphorylation site [posttranslational modification] 272560023357 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560023358 ATP binding site [chemical binding]; other site 272560023359 Mg2+ binding site [ion binding]; other site 272560023360 G-X-G motif; other site 272560023361 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 68.6, E-value 8.6e-18 272560023362 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 47.7, E-value 1.6e-11 272560023363 Pfam match to entry PF00672 HAMP, HAMP domain , score 26.3, E-value 4.7e-05 272560023364 2 probable transmembrane helices predicted for BPSS1460 by TMHMM2.0 at aa 10-32 and 155-177 272560023365 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560023366 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560023367 active site 272560023368 phosphorylation site [posttranslational modification] 272560023369 intermolecular recognition site; other site 272560023370 dimerization interface [polypeptide binding]; other site 272560023371 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560023372 DNA binding site [nucleotide binding] 272560023373 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 90.5, E-value 2.2e-24 272560023374 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 130.0, E-value 2.9e-36 272560023375 Peptidase propeptide and YPEB domain; Region: PepSY_2; pfam13670 272560023376 Signal peptide predicted for BPSS1463 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.960 between residues 22 and 23; signal peptide 272560023377 Predicted periplasmic protein (DUF2271); Region: DUF2271; pfam10029 272560023378 Signal peptide predicted for BPSS1464 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.752 between residues 28 and 29; signal peptide 272560023379 Uncharacterized iron-regulated membrane protein [Function unknown]; Region: PiuB; COG3182 272560023380 PepSY-associated TM helix; Region: PepSY_TM_2; pfam13703 272560023381 Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369 272560023382 Flavodoxin; Region: Flavodoxin_1; pfam00258 272560023383 Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR_like2; cd06201 272560023384 FAD binding pocket [chemical binding]; other site 272560023385 FAD binding motif [chemical binding]; other site 272560023386 catalytic residues [active] 272560023387 NAD binding pocket [chemical binding]; other site 272560023388 phosphate binding motif [ion binding]; other site 272560023389 beta-alpha-beta structure motif; other site 272560023390 Pfam match to entry PF03929 DUF337, Uncharacterized iron-regulated membrane protein (DUF337) , score -26.3, E-value 2.1e-08 272560023391 5 probable transmembrane helices predicted for BPSS1464 by TMHMM2.0 at aa 7-29, 122-144, 173-195, 297-319 and 642-664 272560023392 Pfam match to entry PF00258 flavodoxin, Flavodoxin , score 63.0, E-value 4.1e-16 272560023393 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 32.6, E-value 3.8e-09 272560023394 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 85.2, E-value 8.5e-23 272560023395 Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477 272560023396 Pfam match to entry PF02424 ApbE, ApbE family , score 134.0, E-value 1.8e-37 272560023397 NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130 272560023398 tetrameric interface [polypeptide binding]; other site 272560023399 NAD binding site [chemical binding]; other site 272560023400 catalytic residues [active] 272560023401 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 443.2, E-value 1.5e-130 272560023402 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560023403 Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155 272560023404 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560023405 homodimer interface [polypeptide binding]; other site 272560023406 catalytic residue [active] 272560023407 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 67.4, E-value 1.9e-17 272560023408 Domain of unknown function (DUF1338); Region: DUF1338; pfam07063 272560023409 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560023410 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560023411 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560023412 dimerization interface [polypeptide binding]; other site 272560023413 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 97.9, E-value 1.3e-26 272560023414 Predicted helix-turn-helix motif with score 1643.000, SD 4.78 at aa 21-42, sequence ESFTRAADELALTQSAVSRQIT 272560023415 PS00044 Bacterial regulatory proteins, lysR family signature. 272560023416 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 124.1, E-value 1.7e-34 272560023417 Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604 272560023418 putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329 272560023419 Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665 272560023420 Pfam match to entry PF01266 DAO, FAD dependent oxidoreductase , score -81.6, E-value 0.0012 272560023421 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560023422 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560023423 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 58.5, E-value 9.4e-15 272560023424 Transposase; Region: DEDD_Tnp_IS110; pfam01548 272560023425 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3547 272560023426 Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371 272560023427 Pfam match to entry PF01548 Transposase_9, Transposase , score 112.3, E-value 6.2e-31 272560023428 Pfam match to entry PF02371 Transposase_20, Transposase IS116/IS110/IS902 family , score 136.4, E-value 3.4e-38 272560023429 Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239 272560023430 Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502 272560023431 putative active site [active] 272560023432 catalytic site [active] 272560023433 Putative catalytic domain, repeat 2, of uncharacterized hypothetical proteins similar to Nuc, an endonuclease from Salmonella typhimurium; Region: PLDc_Nuc_like_unchar1_2; cd09173 272560023434 putative active site [active] 272560023435 catalytic site [active] 272560023436 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023437 Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349 272560023438 DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531 272560023439 DeoR C terminal sensor domain; Region: DeoRC; pfam00455 272560023440 Pfam match to entry PF00455 deoR, Bacterial regulatory proteins, deoR family , score 217.3, E-value 1.5e-62 272560023441 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 20-41, sequence LSVAQLVNALNVSRETIRRDLN 272560023442 PS00894 Bacterial regulatory proteins, deoR family signature. 272560023443 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560023444 D-galactonate transporter; Region: 2A0114; TIGR00893 272560023445 putative substrate translocation pore; other site 272560023446 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -102.7, E-value 0.00031 272560023447 10 probable transmembrane helices predicted for BPSS1475 by TMHMM2.0 at aa 21-43, 58-80, 93-115, 172-194, 245-267, 282-304, 317-336, 342-364, 373-395 and 405-427 272560023448 Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246 272560023449 Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232 272560023450 Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125 272560023451 Pfam match to entry PF01232 Mannitol_dh, Mannitol dehydrogenase , score 437.0, E-value 1.1e-128 272560023452 PS00974 Mannitol dehydrogenases signature. 272560023453 Transcriptional regulators [Transcription]; Region: GntR; COG1802 272560023454 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560023455 DNA-binding site [nucleotide binding]; DNA binding site 272560023456 FCD domain; Region: FCD; pfam07729 272560023457 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 54.0, E-value 2.1e-13 272560023458 PS00043 Bacterial regulatory proteins, gntR family signature. 272560023459 bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072 272560023460 Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188 272560023461 metal binding site [ion binding]; metal-binding site 272560023462 substrate binding pocket [chemical binding]; other site 272560023463 Pfam match to entry PF02746 MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain , score 183.2, E-value 2.7e-52 272560023464 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 272560023465 Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain , score 357.5, E-value 9.6e-105 272560023466 putative oxidoreductase; Provisional; Region: PRK10083 272560023467 Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261 272560023468 putative NAD(P) binding site [chemical binding]; other site 272560023469 catalytic Zn binding site [ion binding]; other site 272560023470 structural Zn binding site [ion binding]; other site 272560023471 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 270.4, E-value 1.6e-78 272560023472 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560023473 Probable gene remnant. Similar to the C-terminal region of Burkholderia cepacia transposase SWALL:Q45111 (EMBL:U44828) (419 aa) fasta scores: E(): 6.1e-09, 78.26% id in 46 aa, and to Ralstonia solanacearum ISRso7-transposase TISRso7 SWALL:Q8XEN1 (EMBL:AL646078) (416 aa) fasta scores: E(): 0.00036, 54.34% id in 46 aa;transposase (fragment) 272560023474 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560023475 Signal peptide predicted for BPSS1481 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.348 between residues 24 and 25; signal peptide 272560023476 10 probable transmembrane helices predicted for BPSS1481 by TMHMM2.0 at aa 5-27, 37-59, 66-88, 93-115, 120-142, 152-174, 187-206, 216-238, 245-267 and 271-289 272560023477 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 37.6, E-value 1.8e-08 272560023478 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 22.8, E-value 0.00054 272560023479 NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553 272560023480 homodimer interface [polypeptide binding]; other site 272560023481 NAD binding pocket [chemical binding]; other site 272560023482 ATP binding pocket [chemical binding]; other site 272560023483 Mg binding site [ion binding]; other site 272560023484 active-site loop [active] 272560023485 Pfam match to entry PF02540 NAD_synthase, NAD synthase , score 177.0, E-value 1.9e-50 272560023486 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560023487 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560023488 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 29.6, E-value 4.8e-06 272560023489 Predicted helix-turn-helix motif with score 1966.000, SD 5.88 at aa 36-57, sequence PSITELANASGVSRATAYRYFP 272560023490 hypothetical protein; Provisional; Region: PRK02399 272560023491 1 probable transmembrane helix predicted for BPSS1484 by TMHMM2.0 at aa 93-115 272560023492 PS00290 Immunoglobulins and major histocompatibility complex proteins signature. 272560023493 TIM-barrel signal transduction protein; Region: TIM-br_sig_trns; pfam09370 272560023494 Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821 272560023495 putative hydrophobic ligand binding site [chemical binding]; other site 272560023496 protein interface [polypeptide binding]; other site 272560023497 gate; other site 272560023498 Signal peptide predicted for BPSS1487 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.710 between residues 30 and 31; signal peptide 272560023499 nitrite reductase, copper-containing; Region: Cu_nitrite_red; TIGR02376 272560023500 Cupredoxin domain 1 of Copper-containing nitrite reductase; Region: CuRO_1_CuNIR; cd11020 272560023501 Type 1 (T1) Cu binding site [ion binding]; other site 272560023502 trimer interface [polypeptide binding]; other site 272560023503 Type II Cu binding site [ion binding]; other site 272560023504 Cupredoxin domain 2 of Copper-containing nitrite reductase; Region: CuRO_2_CuNIR; cd04208 272560023505 trimer interface [polypeptide binding]; other site 272560023506 Cu binding site [ion binding]; other site 272560023507 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560023508 Cytochrome c; Region: Cytochrom_C; pfam00034 272560023509 1 probable transmembrane helix predicted for BPSS1487 by TMHMM2.0 at aa 13-35 272560023510 Pfam match to entry PF00394 Cu-oxidase, Multicopper oxidase , score 6.4, E-value 0.0018 272560023511 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 39.3, E-value 5.8e-09 272560023512 PS00190 Cytochrome c family heme-binding site signature. 272560023513 Signal peptide predicted for BPSS1488 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.962 between residues 37 and 38; signal peptide 272560023514 Uncharacterized conserved protein [Function unknown]; Region: COG1262 272560023515 Sulfatase-modifying factor enzyme 1; Region: FGE-sulfatase; cl19582 272560023516 1 probable transmembrane helix predicted for BPSS1488 by TMHMM2.0 at aa 21-38 272560023517 Pfam match to entry PF03781 DUF323, Domain of unknown function (DUF323) , score 98.1, E-value 1.2e-26 272560023518 Signal peptide predicted for BPSS1489 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.967 between residues 26 and 27; signal peptide 272560023519 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560023520 Cu(I) binding site [ion binding]; other site 272560023521 Pfam match to entry PF02630 SCO1-SenC, SCO1/SenC , score -11.1, E-value 3.7e-06 272560023522 Signal peptide predicted for BPSS1490 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.543 between residues 40 and 41; signal peptide 272560023523 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 272560023524 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 272560023525 amidase catalytic site [active] 272560023526 Zn binding residues [ion binding]; other site 272560023527 substrate binding site [chemical binding]; other site 272560023528 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 272560023529 1 probable transmembrane helix predicted for BPSS1490 by TMHMM2.0 at aa 20-39 272560023530 Pfam match to entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase , score 142.5, E-value 4.9e-40 272560023531 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560023532 Domain of unknown function (DUF4589); Region: DUF4589; pfam15252 272560023533 YadA-like, left-handed beta-roll; Region: LbR_YadA-like; cd12820 272560023534 trimer interface [polypeptide binding]; other site 272560023535 Coiled stalk of trimeric autotransporter adhesin; Region: YadA_stalk; pfam05662 272560023536 YadA-like C-terminal region; Region: YadA_anchor; pfam03895 272560023537 ImpA-related N-terminal; Region: ImpA-rel_N; pfam06812 272560023538 type VI secretion-associated protein, VC_A0119 family; Region: VI_chp_7; TIGR03362 272560023539 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560023540 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560023541 active site 272560023542 phosphorylation site [posttranslational modification] 272560023543 intermolecular recognition site; other site 272560023544 dimerization interface [polypeptide binding]; other site 272560023545 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560023546 DNA binding site [nucleotide binding] 272560023547 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 96.2, E-value 4.3e-26 272560023548 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 105.2, E-value 8.1e-29 272560023549 MASE1; Region: MASE1; cl17823 272560023550 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560023551 dimer interface [polypeptide binding]; other site 272560023552 phosphorylation site [posttranslational modification] 272560023553 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560023554 ATP binding site [chemical binding]; other site 272560023555 Mg2+ binding site [ion binding]; other site 272560023556 G-X-G motif; other site 272560023557 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 116.1, E-value 4.5e-32 272560023558 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 17.4, E-value 0.00061 272560023559 9 probable transmembrane helices predicted for BPSS1495 by TMHMM2.0 at aa 33-52, 67-86, 93-115, 119-141, 154-176, 191-213, 225-247, 262-284 and 297-319 272560023560 Protein of unknown function (DUF770); Region: DUF770; pfam05591 272560023561 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 272560023562 type VI secretion system effector, Hcp1 family; Region: VI_effect_Hcp1; TIGR03344 272560023563 type VI secretion system lysozyme-like protein; Region: VI_zyme; TIGR03357 272560023564 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 272560023565 Protein of unknown function (DUF1305); Region: DUF1305; cl01404 272560023566 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560023567 Clp amino terminal domain; Region: Clp_N; pfam02861 272560023568 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560023569 Walker A motif; other site 272560023570 ATP binding site [chemical binding]; other site 272560023571 Walker B motif; other site 272560023572 arginine finger; other site 272560023573 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560023574 Walker A motif; other site 272560023575 ATP binding site [chemical binding]; other site 272560023576 Walker B motif; other site 272560023577 arginine finger; other site 272560023578 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431 272560023579 Pfam match to entry PF02861 Clp_N, Clp amino terminal domain , score 22.4, E-value 0.00064 272560023580 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 25.7, E-value 7.5e-07 272560023581 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023582 PS00870 Chaperonins clpA/B signature 1. 272560023583 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 1.2, E-value 7.1e-05 272560023584 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023585 Rhs element Vgr protein; Region: vgr_GE; TIGR01646 272560023586 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560023587 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560023588 Signal peptide predicted for BPSS1504 by SignalP 2.0 HMM (Signal peptide probability 0.684) with cleavage site probability 0.680 between residues 38 and 39; signal peptide 272560023589 Uncharacterized protein conserved in bacteria (DUF2169); Region: DUF2169; cl02212 272560023590 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 272560023591 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023592 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023593 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023594 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023595 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 33.1, E-value 4.3e-07 272560023596 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 31.4, E-value 1.4e-06 272560023597 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 5.8, E-value 0.11 272560023598 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 17.5, E-value 0.0062 272560023599 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 30.5, E-value 2.5e-06 272560023600 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 45.8, E-value 6.5e-11 272560023601 Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599 272560023602 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023603 Pentapeptide repeats containing protein [Function unknown]; Region: COG1357 272560023604 Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805 272560023605 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 33.4, E-value 3.3e-07 272560023606 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 7.5, E-value 0.072 272560023607 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 14.0, E-value 0.015 272560023608 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 32.2, E-value 8e-07 272560023609 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 24.7, E-value 0.00014 272560023610 Pfam match to entry PF00805 Pentapeptide, Pentapeptide repeats (8 copies) , score 36.9, E-value 3e-08 272560023611 Signal peptide predicted for BPSS1506 by SignalP 2.0 HMM (Signal peptide probability 0.713) with cleavage site probability 0.473 between residues 29 and 30; signal peptide 272560023612 Protein of unknown function (DUF3540); Region: DUF3540; pfam12059 272560023613 Domain of unknown function (DUF4150); Region: DUF4150; pfam13665 272560023614 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 272560023615 type VI secretion protein, VC_A0114 family; Region: VI_chp_4; TIGR03353 272560023616 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560023617 1 probable transmembrane helix predicted for BPSS1510 by TMHMM2.0 at aa 181-203 272560023618 Signal peptide predicted for BPSS1511 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.555 between residues 18 and 19; signal peptide 272560023619 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560023620 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560023621 3 probable transmembrane helices predicted for BPSS1511 by TMHMM2.0 at aa 2-21, 25-47 and 410-432 272560023622 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023623 Bacterial Ig-like domain; Region: Big_5; pfam13205 272560023624 Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly...; Region: Peptidase_C19; cl02553 272560023625 active site 272560023626 Pfam match to entry PF00443 UCH-2, Ubiquitin carboxyl-terminal hydrolase 2 , score 27.2, E-value 2.5e-08 272560023627 GTP cyclohydrolase I; Reviewed; Region: PRK12606 272560023628 active site 272560023629 Pfam match to entry PF01227 GTP_cyclohydroI, GTP cyclohydrolase I , score 73.7, E-value 2.5e-19 272560023630 Partial CDS. Similar to an internal region of several transposases including Clostridium cellulolyticum transposase Tpna1 SWALL:AAN06001 (EMBL:AY130778) (348 aa) fasta scores: E(): 2.5e-19, 53% id in 100 aa, and to Escherichia coli integrase SWALL:CAD33770 (EMBL:AJ488511) (152 aa) fasta scores: E(): 8.5e-20, 52.38% id in 105 aa; transposase (fragment) 272560023631 Winged helix-turn helix; Region: HTH_29; pfam13551 272560023632 Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586 272560023633 Pfam match to entry PF01609 Transposase_11, Transposase DDE domain , score 10.6, E-value 0.00057 272560023634 Cupin domain; Region: Cupin_2; cl17218 272560023635 AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207 272560023636 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023637 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 44.6, E-value 1.4e-10 272560023638 PS00041 Bacterial regulatory proteins, araC family signature. 272560023639 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 17.7, E-value 0.018 272560023640 Predicted helix-turn-helix motif with score 1811.000, SD 5.36 at aa 262-283, sequence LTPERIADAIHCSRTQLYRLFR 272560023641 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560023642 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560023643 active site 272560023644 phosphorylation site [posttranslational modification] 272560023645 intermolecular recognition site; other site 272560023646 dimerization interface [polypeptide binding]; other site 272560023647 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560023648 DNA binding residues [nucleotide binding] 272560023649 dimerization interface [polypeptide binding]; other site 272560023650 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 85.6, E-value 6.4e-23 272560023651 PS00622 Bacterial regulatory proteins, luxR family signature. 272560023652 Predicted helix-turn-helix motif with score 1241.000, SD 3.41 at aa 190-211, sequence MRNREIASLLNISPKTVDCHRQ 272560023653 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 92.1, E-value 7.4e-25 272560023654 chaperone protein SicP; Provisional; Region: PRK15329 272560023655 SicP binding; Region: SicP-binding; pfam09119 272560023656 type III secretion protein BopE; Provisional; Region: PRK15278 272560023657 SopE GEF domain; Region: SopE_GEF; pfam07487 272560023658 Signal peptide predicted for BPSS1526 by SignalP 2.0 HMM (Signal peptide probability 0.603) with cleavage site probability 0.556 between residues 38 and 39; signal peptide 272560023659 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741 272560023660 Lytic Transglycosylase (LT) and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL). LTs...; Region: LT_GEWL; cd00254 272560023661 N-acetyl-D-glucosamine binding site [chemical binding]; other site 272560023662 catalytic residue [active] 272560023663 Pfam match to entry PF01464 SLT, Transglycosylase SLT domain , score 87.5, E-value 1.8e-23 272560023664 1 probable transmembrane helix predicted for BPSS1526 by TMHMM2.0 at aa 21-38 272560023665 Phosphopantetheine attachment site; Region: PP-binding; cl09936 272560023666 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 21.3, E-value 1.9e-05 272560023667 type III effector protein IpaD/SipD/SspD; Region: SipD_IpaD_SspD; TIGR02553 272560023668 H-NS histone family; Region: Histone_HNS; pfam00816 272560023669 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560023670 Salmonella-Shigella invasin protein C (IpaC_SipC); Region: IpaC_SipC; pfam09599 272560023671 pathogenicity island 1 effector protein SipB; Provisional; Region: PRK15374 272560023672 Secretion system effector C (SseC) like family; Region: SseC; pfam04888 272560023673 Pfam match to entry PF03518 Invas_B, Salmonella/Shigella invasin protein B , score 160.1, E-value 2.4e-45 272560023674 2 probable transmembrane helices predicted for BPSS1532 by TMHMM2.0 at aa 345-377 and 430-452 272560023675 Pfam match to entry PF02987 LEA, Late embryogenesis abundant protein , score 8.8, E-value 0.032 272560023676 chaperone protein SicA; Provisional; Region: PRK15331 272560023677 Tetratricopeptide repeat; Region: TPR_3; pfam07720 272560023678 Tetratricopeptide repeat; Region: TPR_3; pfam07720 272560023679 type III secretion system protein SpaS; Validated; Region: PRK08156 272560023680 Signal peptide predicted for BPSS1534 by SignalP 2.0 HMM (Signal peptide probability 0.780) with cleavage site probability 0.599 between residues 40 and 41; signal peptide 272560023681 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family , score 341.2, E-value 7.4e-100 272560023682 4 probable transmembrane helices predicted for BPSS1534 by TMHMM2.0 at aa 28-50, 76-98, 134-153 and 173-195 272560023683 Bacterial export proteins, family 1; Region: Bac_export_1; cl00734 272560023684 Pfam match to entry PF01311 Bac_export_1, Bacterial export proteins, family 1 , score 173.6, E-value 2.1e-49 272560023685 6 probable transmembrane helices predicted for BPSS1535 by TMHMM2.0 at aa 10-32, 37-59, 74-96, 141-163, 178-200 and 207-229 272560023686 Bacterial export proteins, family 3; Region: Bac_export_3; cl00867 272560023687 Signal peptide predicted for BPSS1536 by SignalP 2.0 HMM (Signal peptide probability 0.914) with cleavage site probability 0.768 between residues 26 and 27; signal peptide 272560023688 Pfam match to entry PF01313 Bac_export_3, Bacterial export proteins, family 3 , score 117.3, E-value 1.8e-32 272560023689 2 probable transmembrane helices predicted for BPSS1536 by TMHMM2.0 at aa 12-34 and 54-76 272560023690 Signal peptide predicted for BPSS1537 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.645 between residues 23 and 24; signal peptide 272560023691 type III secretion system protein SpaP; Provisional; Region: spaP; PRK12796 272560023692 Pfam match to entry PF00813 FliP, FliP family , score 340.4, E-value 1.3e-99 272560023693 4 probable transmembrane helices predicted for BPSS1537 by TMHMM2.0 at aa 7-29, 44-66, 165-187 and 192-214 272560023694 PS01061 Flagella transport protein fliP family signature 2. 272560023695 PS01060 Flagella transport protein fliP family signature 1. 272560023696 Surface presentation of antigens (SPOA); Region: SpoA; cl00819 272560023697 type III secretion system apparatus protein YscQ/HrcQ; Region: SpaO_YscQ; TIGR02551 272560023698 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein , score 52.1, E-value 7.8e-13 272560023699 DNA polymerase III subunits gamma and tau; Validated; Region: PRK07003 272560023700 Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196 272560023701 ATP synthase SpaL; Validated; Region: PRK08149 272560023702 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560023703 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560023704 Walker A motif; other site 272560023705 ATP binding site [chemical binding]; other site 272560023706 Walker B motif; other site 272560023707 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 402.7, E-value 2.2e-118 272560023708 PS00152 ATP synthase alpha and beta subunits signature. 272560023709 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023710 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 36.5, E-value 4e-08 272560023711 Invasion protein B family; Region: Invas_SpaK; cl04129 272560023712 type III secretion system protein InvA; Provisional; Region: PRK15337 272560023713 Pfam match to entry PF00771 FHIPEP, FHIPEP family , score 1046.6, E-value 0 272560023714 8 probable transmembrane helices predicted for BPSS1543 by TMHMM2.0 at aa 13-35, 40-62, 69-91, 106-128, 197-219, 239-261, 274-293 and 297-314 272560023715 PS00994 Bacterial export FHIPEP family signature. 272560023716 type III secretion regulator YopN/LcrE/InvE/MxiC; Region: LcrE; TIGR02568 272560023717 TyeA; Region: TyeA; cl07611 272560023718 Pfam match to entry PF02523 InvE, InvE invasion protein , score 133.6, E-value 2.4e-37 272560023719 Signal peptide predicted for BPSS1545 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 26 and 27; signal peptide 272560023720 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 272560023721 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023722 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023723 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560023724 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 229.8, E-value 2.6e-66 272560023725 Pfam match to entry PF03958 NolW-like, NolW-like , score 190.8, E-value 1.4e-54 272560023726 transcriptional regulator InvF; Provisional; Region: PRK15340 272560023727 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023728 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560023729 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 36.9, E-value 2.9e-08 272560023730 PS00041 Bacterial regulatory proteins, araC family signature. 272560023731 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 28.7, E-value 9e-06 272560023732 Predicted helix-turn-helix motif with score 1504.000, SD 4.31 at aa 167-188, sequence QPIAALAARYGVSEPHFRRLCR 272560023733 Type III secretion system protein PrgH-EprH (PrgH); Region: PrgH; cl12363 272560023734 2 probable transmembrane helices predicted for BPSS1547 by TMHMM2.0 at aa 15-37 and 174-196 272560023735 Type III secretion needle MxiH like; Region: MxiH; cl09641 272560023736 type III secretion system needle complex protein PrgJ; Provisional; Region: PRK15325 272560023737 Signal peptide predicted for BPSS1550 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.589 between residues 21 and 22; signal peptide 272560023738 Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907 272560023739 Pfam match to entry PF01514 YscJ_FliF, Secretory protein of YscJ/FliF family , score 179.1, E-value 4.8e-51 272560023740 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560023741 1 probable transmembrane helix predicted for BPSS1550 by TMHMM2.0 at aa 210-232 272560023742 type III secretion apparatus protein OrgA/MxiK; Region: OrgA_MxiK; TIGR02555 272560023743 type III secretion apparatus protein, HrpE/YscL family; Region: HrpE_YscL_not; TIGR02499 272560023744 invasion protein OrgB; Provisional; Region: PRK15322 272560023745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560023746 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cl17355 272560023747 DNA binding site [nucleotide binding] 272560023748 1 probable transmembrane helix predicted for BPSS1553 by TMHMM2.0 at aa 222-244 272560023749 Zinc metalloprotease (elastase) [Amino acid transport and metabolism]; Region: LasB; COG3227 272560023750 Signal peptide predicted for BPSS1555 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.816 between residues 24 and 25; signal peptide 272560023751 Fungalysin/Thermolysin Propeptide Motif; Region: FTP; pfam07504 272560023752 Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413 272560023753 Peptidase M4 family includes thermolysin, protealysin, aureolysin and neutral protease; Region: M4_neutral_protease; cd09597 272560023754 active site 272560023755 Zn binding site [ion binding]; other site 272560023756 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560023757 Pfam match to entry PF03413 Pep_M4_propep, Thermolysin metallopeptidase, propeptide , score 12.2, E-value 2.1e-05 272560023758 Pfam match to entry PF01447 Peptidase_M4, Thermolysin metallopeptidase, catalytic domain , score 32.9, E-value 4.9e-09 272560023759 PS00201 Flavodoxin signature. 272560023760 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560023761 Pfam match to entry PF02868 Peptidase_M4_C, Thermolysin metallopeptidase, alpha-helical domain , score 129.4, E-value 4.2e-36 272560023762 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560023763 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560023764 Pfam match to entry PF01047 MarR, MarR family , score 52.3, E-value 6.9e-13 272560023765 Predicted helix-turn-helix motif with score 1251.000, SD 3.45 at aa 121-142, sequence VTPSYMAEYFGVTRSTVTGLLD 272560023766 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_9; cd07245 272560023767 dimer interface [polypeptide binding]; other site 272560023768 putative metal binding site [ion binding]; other site 272560023769 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 17.2, E-value 8.5e-05 272560023770 alpha-ketoglutarate transporter; Provisional; Region: PRK10406 272560023771 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560023772 putative substrate translocation pore; other site 272560023773 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 173.7, E-value 1.9e-49 272560023774 12 probable transmembrane helices predicted for BPSS1558 by TMHMM2.0 at aa 39-61, 66-88, 95-114, 118-140, 160-182, 197-216, 248-270, 285-307, 314-336, 341-363, 376-398 and 408-427 272560023775 PS00217 Sugar transport proteins signature 2. 272560023776 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560023777 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560023778 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560023779 dimerization interface [polypeptide binding]; other site 272560023780 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 124.5, E-value 1.3e-34 272560023781 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 64.7, E-value 1.3e-16 272560023782 PS00044 Bacterial regulatory proteins, lysR family signature. 272560023783 Predicted helix-turn-helix motif with score 1277.000, SD 3.54 at aa 19-40, sequence ANFSTAAQRLHLSISSLSKRIN 272560023784 Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809 272560023785 FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070 272560023786 active site 272560023787 substrate binding site [chemical binding]; other site 272560023788 FMN binding site [chemical binding]; other site 272560023789 putative catalytic residues [active] 272560023790 Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase , score 397.0, E-value 1.2e-116 272560023791 PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 272560023792 Carboxypeptidase C (cathepsin A) [Amino acid transport and metabolism]; Region: COG2939 272560023793 Serine carboxypeptidase; Region: Peptidase_S10; cl08270 272560023794 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 272560023795 peptidase domain interface [polypeptide binding]; other site 272560023796 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 272560023797 active site 272560023798 catalytic triad [active] 272560023799 calcium binding site [ion binding]; other site 272560023800 Signal peptide predicted for BPSS1563 by SignalP 2.0 HMM (Signal peptide probability 0.935) with cleavage site probability 0.709 between residues 19 and 20; signal peptide 272560023801 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560023802 Pfam match to entry PF01810 LysE, LysE type translocator , score 66.8, E-value 3.1e-17 272560023803 4 probable transmembrane helices predicted for BPSS1563 by TMHMM2.0 at aa 7-29, 44-66, 79-101 and 143-165 272560023804 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560023805 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560023806 putative DNA binding site [nucleotide binding]; other site 272560023807 putative Zn2+ binding site [ion binding]; other site 272560023808 AsnC family; Region: AsnC_trans_reg; pfam01037 272560023809 Predicted helix-turn-helix motif with score 973.000, SD 2.50 at aa 41-62, sequence IPVARLADSVGLSETPCARRLK 272560023810 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 125.6, E-value 6e-35 272560023811 Putative hydrophobic ligand-binding SRPBCC domain of Micromonospora echinospora CalC, human Aha1, and related proteins; Region: SRPBCC_CalC_Aha1-like; cd07814 272560023812 putative hydrophobic ligand binding site [chemical binding]; other site 272560023813 Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306 272560023814 10 probable transmembrane helices predicted for BPSS1566 by TMHMM2.0 at aa 19-41, 51-73, 93-115, 135-157, 164-181, 196-218, 238-255, 265-282, 410-432 and 502-524 272560023815 Pfam match to entry PF01384 PHO4, Phosphate transporter family , score 207.2, E-value 1.6e-59 272560023816 Oxygenase, catalyzing oxidative methylation of damaged DNA; Region: Oxygenase-NA; pfam09859 272560023817 acyl-CoA ligase (AMP-forming), exosortase A-associated; Region: ligase_PEP_1; TIGR03098 272560023818 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560023819 Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_6; cd05922 272560023820 acyl-activating enzyme (AAE) consensus motif; other site 272560023821 acyl-activating enzyme (AAE) consensus motif; other site 272560023822 putative AMP binding site [chemical binding]; other site 272560023823 putative active site [active] 272560023824 putative CoA binding site [chemical binding]; other site 272560023825 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 388.4, E-value 4.6e-114 272560023826 1 probable transmembrane helix predicted for BPSS1568 by TMHMM2.0 at aa 167-189 272560023827 PS00455 AMP-binding domain signature. 272560023828 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560023829 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560023830 DNA binding residues [nucleotide binding] 272560023831 dimerization interface [polypeptide binding]; other site 272560023832 Pfam match to entry PF03472 Autoind_bind, Autoinducer binding domain , score 65.0, E-value 1e-16 272560023833 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 67.5, E-value 1.8e-17 272560023834 PS00622 Bacterial regulatory proteins, luxR family signature. 272560023835 Autoinducer synthetase; Region: Autoind_synth; cl17404 272560023836 Pfam match to entry PF00765 Autoind_synth, Autoinducer synthetase , score 22.8, E-value 8.8e-11 272560023837 PS00949 Autoinducers synthetases family signature. 272560023838 Old yellow enzyme (OYE)-related FMN binding domain, group 2. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as...; Region: OYE_like_2_FMN; cd04733 272560023839 putative active site [active] 272560023840 putative FMN binding site [chemical binding]; other site 272560023841 putative substrate binding site [chemical binding]; other site 272560023842 putative catalytic residue [active] 272560023843 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 192.2, E-value 5.3e-55 272560023844 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600 272560023845 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560023846 dimer interface [polypeptide binding]; other site 272560023847 conserved gate region; other site 272560023848 putative PBP binding loops; other site 272560023849 ABC-ATPase subunit interface; other site 272560023850 6 probable transmembrane helices predicted for BPSS1572 by TMHMM2.0 at aa 33-55, 96-118, 131-153, 158-180, 221-243 and 253-275 272560023851 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 36.8, E-value 3.1e-08 272560023852 ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293 272560023853 taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248 272560023854 Walker A/P-loop; other site 272560023855 ATP binding site [chemical binding]; other site 272560023856 Q-loop/lid; other site 272560023857 ABC transporter signature motif; other site 272560023858 Walker B; other site 272560023859 D-loop; other site 272560023860 H-loop/switch region; other site 272560023861 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 179.3, E-value 4.1e-51 272560023862 PS00211 ABC transporters family signature. 272560023863 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023864 Signal peptide predicted for BPSS1574 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.502 between residues 27 and 28; signal peptide 272560023865 ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728 272560023866 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560023867 substrate binding pocket [chemical binding]; other site 272560023868 membrane-bound complex binding site; other site 272560023869 hinge residues; other site 272560023870 taurine dioxygenase; Reviewed; Region: tauD; PRK09553 272560023871 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560023872 active site 272560023873 iron coordination sites [ion binding]; other site 272560023874 substrate binding pocket [chemical binding]; other site 272560023875 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 340.0, E-value 1.8e-99 272560023876 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 272560023877 cellulose synthase operon protein YhjU; Region: cellulose_yhjU; TIGR03368 272560023878 PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 272560023879 3 probable transmembrane helices predicted for BPSS1576 by TMHMM2.0 at aa 12-34, 91-113 and 120-142 272560023880 cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498 272560023881 CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421 272560023882 DXD motif; other site 272560023883 PilZ domain; Region: PilZ; pfam07238 272560023884 8 probable transmembrane helices predicted for BPSS1577 by TMHMM2.0 at aa 149-166, 170-189, 196-214, 229-251, 527-549, 553-575, 638-657 and 667-689 272560023885 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 88.0, E-value 1.3e-23 272560023886 cellulose synthase operon protein YhjQ; Region: cellulose_yhjQ; TIGR03371 272560023887 Signal peptide predicted for BPSS1578 by SignalP 2.0 HMM (Signal peptide probability 0.983) with cleavage site probability 0.821 between residues 23 and 24; signal peptide 272560023888 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560023889 Protein of unknown function (DUF2819); Region: DUF2819; cl17862 272560023890 Signal peptide predicted for BPSS1580 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.403 between residues 38 and 39; signal peptide 272560023891 cellulose synthase subunit BcsC; Provisional; Region: PRK11447 272560023892 Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420 272560023893 Pfam match to entry PF00515 TPR, TPR Domain , score 1.2, E-value 2.2 272560023894 Pfam match to entry PF00515 TPR, TPR Domain , score 11.5, E-value 0.17 272560023895 Pfam match to entry PF00515 TPR, TPR Domain , score 29.9, E-value 3.9e-06 272560023896 Pfam match to entry PF00515 TPR, TPR Domain , score 13.6, E-value 0.1 272560023897 1 probable transmembrane helix predicted for BPSS1580 by TMHMM2.0 at aa 16-38 272560023898 endo-1,4-D-glucanase; Provisional; Region: PRK11097 272560023899 Pfam match to entry PF01270 Glyco_hydro_8, Glycosyl hydrolases family 8 , score 189.6, E-value 3.3e-54 272560023900 cellulose synthase regulator protein; Provisional; Region: PRK11114 272560023901 1 probable transmembrane helix predicted for BPSS1582 by TMHMM2.0 at aa 685-707 272560023902 Pfam match to entry PF03170 BcsB, Bacterial cellulose synthase subunit , score 448.2, E-value 4.7e-132 272560023903 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560023904 non-specific DNA binding site [nucleotide binding]; other site 272560023905 salt bridge; other site 272560023906 sequence-specific DNA binding site [nucleotide binding]; other site 272560023907 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 52.1, E-value 7.8e-13 272560023908 Predicted helix-turn-helix motif with score 1526.000, SD 4.38 at aa 28-49, sequence LTQAMLASRLGVTQQTYAQFEA 272560023909 HipA N-terminal domain; Region: Couple_hipA; cl11853 272560023910 Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550 272560023911 HipA-like N-terminal domain; Region: HipA_N; pfam07805 272560023912 HipA-like C-terminal domain; Region: HipA_C; pfam07804 272560023913 Signal peptide predicted for BPSS1585 by SignalP 2.0 HMM (Signal peptide probability 0.661) with cleavage site probability 0.508 between residues 36 and 37; signal peptide 272560023914 2 probable transmembrane helices predicted for BPSS1585 by TMHMM2.0 at aa 13-35 and 111-133 272560023915 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560023916 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560023917 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466 272560023918 dimerization interface [polypeptide binding]; other site 272560023919 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 98.1, E-value 1.2e-26 272560023920 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 69.5, E-value 4.5e-18 272560023921 Predicted helix-turn-helix motif with score 1004.000, SD 2.61 at aa 23-44, sequence GGVSAAQATLNVSQPTISTQLA 272560023922 Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592 272560023923 oligomer interface [polypeptide binding]; other site 272560023924 putative active site [active] 272560023925 Mn binding site [ion binding]; other site 272560023926 Pfam match to entry PF00491 arginase, Arginase , score 206.9, E-value 2e-59 272560023927 PS00147 Arginase signature 1. 272560023928 PS00148 Arginase signature 2. 272560023929 PS01053 Arginase signature 3. 272560023930 Signal peptide predicted for BPSS1588 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.892 between residues 21 and 22; signal peptide 272560023931 5 probable transmembrane helices predicted for BPSS1591 by TMHMM2.0 at aa 119-141, 156-178, 191-213, 228-250 and 271-293 272560023932 Signal peptide predicted for BPSS1592 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.982 between residues 22 and 23; signal peptide 272560023933 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 272560023934 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023935 Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958 272560023936 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560023937 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 292.4, E-value 3.6e-85 272560023938 Pfam match to entry PF03958 NolW-like, NolW-like , score 229.2, E-value 3.8e-66 272560023939 Signal peptide predicted for BPSS1593 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.448 between residues 32 and 33; signal peptide 272560023940 Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917 272560023941 Signal peptide predicted for BPSS1594 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.771 between residues 18 and 19; signal peptide 272560023942 PilM; Region: PilM; pfam07419 272560023943 PilS N terminal; Region: PilS; pfam08805 272560023944 1 probable transmembrane helix predicted for BPSS1595 by TMHMM2.0 at aa 28-50 272560023945 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560023946 Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482 272560023947 Pfam match to entry PF00482 GSPII_F, Bacterial type II secretion system protein F domain , score -5.3, E-value 6.3e-10 272560023948 3 probable transmembrane helices predicted for BPSS1596 by TMHMM2.0 at aa 120-142, 173-195 and 324-346 272560023949 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560023950 Walker A motif; other site 272560023951 ATP binding site [chemical binding]; other site 272560023952 Walker B motif; other site 272560023953 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score 159.0, E-value 5.3e-45 272560023954 PS00662 Bacterial type II secretion system protein E signature. 272560023955 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023956 Signal peptide predicted for BPSS1598 by SignalP 2.0 HMM (Signal peptide probability 0.994) with cleavage site probability 0.825 between residues 16 and 17; signal peptide 272560023957 type IV pilus biogenesis protein PilP; Region: pilP_fam; TIGR03021 272560023958 Pilin accessory protein (PilO); Region: PAP_PilO; pfam06864 272560023959 type IVB pilus formation outer membrane protein, R64 PilN family; Region: pilus_B_mal_scr; TIGR02520 272560023960 Secretin N-terminal domain; Region: Secretin_N_2; pfam07655 272560023961 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560023962 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 95.9, E-value 5.1e-26 272560023963 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023964 Signal peptide predicted for BPSS1601 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.328 between residues 19 and 20; signal peptide 272560023965 Toxin co-regulated pilus biosynthesis protein Q; Region: TcpQ; pfam10671 272560023966 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560023967 Walker A motif; other site 272560023968 ATP binding site [chemical binding]; other site 272560023969 Walker B motif; other site 272560023970 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score 79.5, E-value 4.5e-21 272560023971 Pfam match to entry PF03029 ATP-bind, Conserved hypothetical ATP binding protein , score 24.0, E-value 2.5e-07 272560023972 PS00017 ATP/GTP-binding site motif A (P-loop). 272560023973 PS00662 Bacterial type II secretion system protein E signature. 272560023974 Signal peptide predicted for BPSS1603 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.945 between residues 20 and 21; signal peptide 272560023975 type III secretion outer membrane pore, YscC/HrcC family; Region: type_III_yscC; TIGR02516 272560023976 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score -80.8, E-value 0.00096 272560023977 PS00211 ABC transporters family signature. 272560023978 Pfam match to entry PF03958 NolW-like, NolW-like , score 80.3, E-value 2.7e-21 272560023979 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560023980 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560023981 active site 272560023982 phosphorylation site [posttranslational modification] 272560023983 intermolecular recognition site; other site 272560023984 dimerization interface [polypeptide binding]; other site 272560023985 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560023986 DNA binding site [nucleotide binding] 272560023987 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 51.1, E-value 1.6e-12 272560023988 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 137.7, E-value 1.3e-38 272560023989 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560023990 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560023991 ATP binding site [chemical binding]; other site 272560023992 Mg2+ binding site [ion binding]; other site 272560023993 G-X-G motif; other site 272560023994 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 77.1, E-value 2.4e-20 272560023995 Signal peptide predicted for BPSS1607 by SignalP 2.0 HMM (Signal peptide probability 0.839) with cleavage site probability 0.778 between residues 28 and 29; signal peptide 272560023996 Bacterial type III secretion protein (HrpB1_HrpK); Region: HrpB1_HrpK; pfam09613 272560023997 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560023998 Signal peptide predicted for BPSS1610 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.556 between residues 23 and 24; signal peptide 272560023999 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560024000 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560024001 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 15.5, E-value 0.055 272560024002 PS00041 Bacterial regulatory proteins, araC family signature. 272560024003 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.3, E-value 1.2e-08 272560024004 Predicted helix-turn-helix motif with score 1183.000, SD 3.22 at aa 394-415, sequence LSVREIAAHIDVTERALQAAFK 272560024005 Tir chaperone protein (CesT) family; Region: CesT; cl08444 272560024006 Signal peptide predicted for BPSS1612 by SignalP 2.0 HMM (Signal peptide probability 0.927) with cleavage site probability 0.441 between residues 27 and 28; signal peptide 272560024007 type III secretion apparatus protein, YscD/HrpQ family; Region: type_III_yscD; TIGR02500 272560024008 1 probable transmembrane helix predicted for BPSS1614 by TMHMM2.0 at aa 129-151 272560024009 Bacterial export proteins, family 3; Region: Bac_export_3; cl00867 272560024010 Pfam match to entry PF01313 Bac_export_3, Bacterial export proteins, family 3 , score 111.8, E-value 8.4e-31 272560024011 2 probable transmembrane helices predicted for BPSS1616 by TMHMM2.0 at aa 15-37 and 49-71 272560024012 type III secretion system protein YscR; Provisional; Region: PRK12797 272560024013 Signal peptide predicted for BPSS1617 by SignalP 2.0 HMM (Signal peptide probability 0.973) with cleavage site probability 0.534 between residues 31 and 32; signal peptide 272560024014 4 probable transmembrane helices predicted for BPSS1617 by TMHMM2.0 at aa 7-29, 52-74, 159-181 and 191-213 272560024015 Pfam match to entry PF00813 FliP, FliP family , score 330.7, E-value 1.1e-96 272560024016 PS01061 Flagella transport protein fliP family signature 2. 272560024017 PS00043 Bacterial regulatory proteins, gntR family signature. 272560024018 type III secretion system apparatus protein YscQ/HrcQ; Region: SpaO_YscQ; TIGR02551 272560024019 Surface presentation of antigens (SPOA); Region: SpoA; pfam01052 272560024020 Pfam match to entry PF01052 SpoA, Surface presentation of antigens (SPOA) protein , score 70.5, E-value 2.3e-18 272560024021 type III secretion protein HpaP; Region: HpaP; TIGR02557 272560024022 FHIPEP family; Region: FHIPEP; cl07980 272560024023 Pfam match to entry PF00771 FHIPEP, FHIPEP family , score 1051.3, E-value 0 272560024024 5 probable transmembrane helices predicted for BPSS1620 by TMHMM2.0 at aa 7-29, 44-66, 106-128, 196-218 and 285-307 272560024025 PS00994 Bacterial export FHIPEP family signature. 272560024026 type III secretion system protein HrcU; Validated; Region: PRK09108 272560024027 Pfam match to entry PF01312 Bac_export_2, FlhB HrpN YscU SpaS Family , score 406.0, E-value 2.3e-119 272560024028 4 probable transmembrane helices predicted for BPSS1621 by TMHMM2.0 at aa 35-57, 80-102, 148-170 and 180-202 272560024029 type III secretion protein HrpB1/HrpK; Region: HrpB1_HrpK; TIGR02561 272560024030 type III secretion protein HrpB2; Region: HrpB2; TIGR02558 272560024031 Signal peptide predicted for BPSS1624 by SignalP 2.0 HMM (Signal peptide probability 0.636) with cleavage site probability 0.345 between residues 22 and 23; signal peptide 272560024032 type III secretion apparatus lipoprotein, YscJ/HrcJ family; Region: III_secr_YscJ; TIGR02544 272560024033 Pfam match to entry PF01514 YscJ_FliF, Secretory protein of YscJ/FliF family , score 305.9, E-value 3.1e-89 272560024034 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560024035 1 probable transmembrane helix predicted for BPSS1624 by TMHMM2.0 at aa 226-248 272560024036 type III secretion protein HrpB4; Region: HrpB4; TIGR02560 272560024037 type III secretion system protein HrpB; Validated; Region: PRK09098 272560024038 Flagellar assembly protein FliH; Region: FliH; cl19405 272560024039 type III secretion system ATPase; Provisional; Region: PRK09099 272560024040 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560024041 Walker A motif; other site 272560024042 ATP binding site [chemical binding]; other site 272560024043 Walker B motif; other site 272560024044 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 24.7, E-value 0.00014 272560024045 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 502.6, E-value 2e-148 272560024046 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024047 PS00152 ATP synthase alpha and beta subunits signature. 272560024048 type III secretion protein HrpB7; Region: HrpB7; TIGR02559 272560024049 Bacterial export proteins, family 1; Region: Bac_export_1; cl00734 272560024050 Pfam match to entry PF01311 Bac_export_1, Bacterial export proteins, family 1 , score 178.8, E-value 5.7e-51 272560024051 6 probable transmembrane helices predicted for BPSS1629 by TMHMM2.0 at aa 19-41, 56-78, 85-107, 135-157, 192-214 and 224-246 272560024052 Pfam match to entry PF01391 Collagen, Collagen triple helix repeat (20 copies) , score 34.9, E-value 1.2e-07 272560024053 Taurine catabolism dioxygenase TauD, TfdA family; Region: TauD; pfam02668 272560024054 substrate binding pocket [chemical binding]; other site 272560024055 active site 272560024056 iron coordination sites [ion binding]; other site 272560024057 Condensation domain; Region: Condensation; cl19241 272560024058 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024059 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024060 acyl-activating enzyme (AAE) consensus motif; other site 272560024061 AMP binding site [chemical binding]; other site 272560024062 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024063 Condensation domain; Region: Condensation; pfam00668 272560024064 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024065 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024066 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024067 acyl-activating enzyme (AAE) consensus motif; other site 272560024068 AMP binding site [chemical binding]; other site 272560024069 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024070 Condensation domain; Region: Condensation; pfam00668 272560024071 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024072 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024073 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024074 acyl-activating enzyme (AAE) consensus motif; other site 272560024075 AMP binding site [chemical binding]; other site 272560024076 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024077 Condensation domain; Region: Condensation; cl19241 272560024078 The adenylation domain of nonribosomal peptide synthetases (NRPS), including salinosporamide A polyketide synthase; Region: A_NRPS_Ta1_like; cd12116 272560024079 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560024080 acyl-activating enzyme (AAE) consensus motif; other site 272560024081 AMP binding site [chemical binding]; other site 272560024082 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024083 enterobactin synthase subunit F; Provisional; Region: entF; PRK10252 272560024084 Condensation domain; Region: Condensation; pfam00668 272560024085 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024086 The adenylation domain of nonribosomal peptide synthetases (NRPS), including Bacillus subtilis termination module Surfactin (SrfA-C); Region: A_NRPS_Srf_like; cd12117 272560024087 acyl-activating enzyme (AAE) consensus motif; other site 272560024088 AMP binding site [chemical binding]; other site 272560024089 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024090 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 272560024091 Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319 272560024092 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560024093 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 78.4, E-value 9.6e-21 272560024094 PS00216 Sugar transport proteins signature 1. 272560024095 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 82.0, E-value 7.7e-22 272560024096 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 62.0, E-value 8.4e-16 272560024097 PS00012 Phosphopantetheine attachment site. 272560024098 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 508.6, E-value 2.9e-150 272560024099 PS00455 AMP-binding domain signature. 272560024100 Pfam match to entry PF00668 Condensation, Condensation domain , score 335.5, E-value 3.8e-98 272560024101 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 0.3, E-value 2.9 272560024102 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 60.7, E-value 2e-15 272560024103 PS00012 Phosphopantetheine attachment site. 272560024104 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 544.2, E-value 6e-161 272560024105 PS00455 AMP-binding domain signature. 272560024106 Pfam match to entry PF00668 Condensation, Condensation domain , score 110.8, E-value 1.7e-30 272560024107 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 46.9, E-value 3e-11 272560024108 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 499.5, E-value 1.7e-147 272560024109 PS00455 AMP-binding domain signature. 272560024110 Pfam match to entry PF00668 Condensation, Condensation domain , score 316.1, E-value 2.6e-92 272560024111 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 77.4, E-value 1.9e-20 272560024112 PS00012 Phosphopantetheine attachment site. 272560024113 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 574.3, E-value 5.1e-170 272560024114 PS00455 AMP-binding domain signature. 272560024115 Pfam match to entry PF00668 Condensation, Condensation domain , score 321.8, E-value 5.2e-94 272560024116 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 77.7, E-value 1.6e-20 272560024117 PS00012 Phosphopantetheine attachment site. 272560024118 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 566.4, E-value 1.2e-167 272560024119 PS00455 AMP-binding domain signature. 272560024120 Pfam match to entry PF00668 Condensation, Condensation domain , score 146.6, E-value 2.9e-41 272560024121 Condensation domain; Region: Condensation; cl19241 272560024122 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024123 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560024124 acyl-activating enzyme (AAE) consensus motif; other site 272560024125 AMP binding site [chemical binding]; other site 272560024126 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024127 Condensation domain; Region: Condensation; pfam00668 272560024128 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024129 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024130 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024131 acyl-activating enzyme (AAE) consensus motif; other site 272560024132 AMP binding site [chemical binding]; other site 272560024133 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024134 Condensation domain; Region: Condensation; cl19241 272560024135 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024136 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560024137 acyl-activating enzyme (AAE) consensus motif; other site 272560024138 AMP binding site [chemical binding]; other site 272560024139 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024140 Condensation domain; Region: Condensation; pfam00668 272560024141 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024142 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024143 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024144 acyl-activating enzyme (AAE) consensus motif; other site 272560024145 AMP binding site [chemical binding]; other site 272560024146 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024147 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 57.7, E-value 1.6e-14 272560024148 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 500.9, E-value 6.1e-148 272560024149 PS00455 AMP-binding domain signature. 272560024150 Pfam match to entry PF00668 Condensation, Condensation domain , score 321.1, E-value 8.2e-94 272560024151 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 76.6, E-value 3.3e-20 272560024152 PS00012 Phosphopantetheine attachment site. 272560024153 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 520.5, E-value 8e-154 272560024154 PS00455 AMP-binding domain signature. 272560024155 Pfam match to entry PF00668 Condensation, Condensation domain , score 113.8, E-value 2.2e-31 272560024156 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 62.7, E-value 5e-16 272560024157 PS00012 Phosphopantetheine attachment site. 272560024158 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 574.4, E-value 4.7e-170 272560024159 PS00455 AMP-binding domain signature. 272560024160 Pfam match to entry PF00668 Condensation, Condensation domain , score 322.1, E-value 4.1e-94 272560024161 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 77.4, E-value 1.9e-20 272560024162 PS00012 Phosphopantetheine attachment site. 272560024163 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 549.9, E-value 1.1e-162 272560024164 PS00455 AMP-binding domain signature. 272560024165 Pfam match to entry PF00668 Condensation, Condensation domain , score 123.2, E-value 3.1e-34 272560024166 Condensation domain; Region: Condensation; cl19241 272560024167 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024168 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024169 acyl-activating enzyme (AAE) consensus motif; other site 272560024170 AMP binding site [chemical binding]; other site 272560024171 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024172 Condensation domain; Region: Condensation; cl19241 272560024173 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024174 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024175 acyl-activating enzyme (AAE) consensus motif; other site 272560024176 AMP binding site [chemical binding]; other site 272560024177 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024178 Condensation domain; Region: Condensation; pfam00668 272560024179 Non-ribosomal peptide synthetase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: EntF; COG1020 272560024180 HxxPF-repeated domain; Region: HxxPF_rpt; pfam13745 272560024181 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560024182 acyl-activating enzyme (AAE) consensus motif; other site 272560024183 AMP binding site [chemical binding]; other site 272560024184 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560024185 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 70.4, E-value 2.4e-18 272560024186 PS00012 Phosphopantetheine attachment site. 272560024187 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 596.7, E-value 9.1e-177 272560024188 PS00455 AMP-binding domain signature. 272560024189 Pfam match to entry PF00668 Condensation, Condensation domain , score 319.7, E-value 2.2e-93 272560024190 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 79.1, E-value 6e-21 272560024191 PS00012 Phosphopantetheine attachment site. 272560024192 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 501.7, E-value 3.5e-148 272560024193 PS00455 AMP-binding domain signature. 272560024194 Pfam match to entry PF00668 Condensation, Condensation domain , score 122.0, E-value 7.1e-34 272560024195 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 65.4, E-value 7.8e-17 272560024196 PS00012 Phosphopantetheine attachment site. 272560024197 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560024198 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 597.3, E-value 6.2e-177 272560024199 PS00455 AMP-binding domain signature. 272560024200 Pfam match to entry PF00668 Condensation, Condensation domain , score 108.8, E-value 6.9e-30 272560024201 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560024202 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560024203 inhibitor-cofactor binding pocket; inhibition site 272560024204 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560024205 catalytic residue [active] 272560024206 H+ Antiporter protein; Region: 2A0121; TIGR00900 272560024207 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560024208 putative substrate translocation pore; other site 272560024209 9 probable transmembrane helices predicted for BPSS1635 by TMHMM2.0 at aa 552-574, 581-603, 676-698, 705-727, 766-788, 795-817, 822-844, 856-878 and 906-928 272560024210 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 444.3, E-value 7e-131 272560024211 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560024212 pyruvate dehydrogenase; Provisional; Region: PRK09124 272560024213 Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039 272560024214 PYR/PP interface [polypeptide binding]; other site 272560024215 tetramer interface [polypeptide binding]; other site 272560024216 dimer interface [polypeptide binding]; other site 272560024217 TPP binding site [chemical binding]; other site 272560024218 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560024219 Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014 272560024220 TPP-binding site [chemical binding]; other site 272560024221 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 203.3, E-value 2.4e-58 272560024222 PS00187 Thiamine pyrophosphate enzymes signature. 272560024223 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 102.3, E-value 6.2e-28 272560024224 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 217.0, E-value 1.8e-62 272560024225 Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427 272560024226 Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550 272560024227 Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336 272560024228 Pfam match to entry PF02550 AcetylCoA_hydro, Acetyl-CoA hydrolase/transferase , score 271.3, E-value 8.2e-79 272560024229 FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451 272560024230 putative active site [active] 272560024231 putative catalytic site [active] 272560024232 Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain , score 71.4, E-value 1.2e-18 272560024233 Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301 272560024234 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560024235 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560024236 The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_1; cd08421 272560024237 putative dimerization interface [polypeptide binding]; other site 272560024238 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 124.9, E-value 9.8e-35 272560024239 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 54.9, E-value 1.2e-13 272560024240 PS00044 Bacterial regulatory proteins, lysR family signature. 272560024241 Partial CDS. This CDS is truncated at the N-terminal region and contains an in-frame stop codon. Similar to the C-terminal region of Ralstonia solanacearum hypothetical transmembrane protein rsp1338 or rs04763 or rsp1307 or rs05692 SWALL:Q8XGL9 (EMBL:AL646084) (540 aa) fasta scores: E(): 1.5e-10, 47.05% id in 102 aa;conserved hypothetical protein (fragment) 272560024242 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560024243 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560024244 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560024245 putative effector binding pocket; other site 272560024246 dimerization interface [polypeptide binding]; other site 272560024247 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 132.0, E-value 7.3e-37 272560024248 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 86.4, E-value 3.6e-23 272560024249 PS00044 Bacterial regulatory proteins, lysR family signature. 272560024250 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560024251 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560024252 putative substrate translocation pore; other site 272560024253 12 probable transmembrane helices predicted for BPSS1644 by TMHMM2.0 at aa 13-35, 45-67, 80-102, 135-157, 164-186, 196-218, 267-289, 294-316, 329-351, 356-378, 399-421 and 431-450 272560024254 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4460 272560024255 Protein of unknown function (DUF1151); Region: DUF1151; pfam06625 272560024256 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560024257 ATP binding site [chemical binding]; other site 272560024258 Mg2+ binding site [ion binding]; other site 272560024259 G-X-G motif; other site 272560024260 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 149.9, E-value 2.8e-42 272560024261 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 34.8, E-value 1.3e-07 272560024262 Signal peptide predicted for BPSS1647 by SignalP 2.0 HMM (Signal peptide probability 0.993) with cleavage site probability 0.977 between residues 24 and 25; signal peptide 272560024263 Uncharacterized conserved protein [Function unknown]; Region: COG3287 272560024264 FIST N domain; Region: FIST; pfam08495 272560024265 FIST C domain; Region: FIST_C; pfam10442 272560024266 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560024267 Signal peptide predicted for BPSS1648 by SignalP 2.0 HMM (Signal peptide probability 0.779) with cleavage site probability 0.353 between residues 20 and 21; signal peptide 272560024268 Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms]; Region: COG3437 272560024269 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560024270 active site 272560024271 phosphorylation site [posttranslational modification] 272560024272 intermolecular recognition site; other site 272560024273 dimerization interface [polypeptide binding]; other site 272560024274 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077 272560024275 Zn2+ binding site [ion binding]; other site 272560024276 Mg2+ binding site [ion binding]; other site 272560024277 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 113.3, E-value 3e-31 272560024278 Signal peptide predicted for BPSS1649 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.841 between residues 30 and 31; signal peptide 272560024279 Ricin-type beta-trefoil; Region: RICIN; smart00458 272560024280 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 272560024281 putative sugar binding sites [chemical binding]; other site 272560024282 Q-X-W motif; other site 272560024283 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 272560024284 putative sugar binding sites [chemical binding]; other site 272560024285 Q-X-W motif; other site 272560024286 Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161 272560024287 Ricin-type beta-trefoil lectin domain; Region: Ricin_B_lectin; pfam00652 272560024288 putative sugar binding sites [chemical binding]; other site 272560024289 Q-X-W motif; other site 272560024290 Kelch motif; Region: Kelch_6; pfam13964 272560024291 C-terminal Early set domain associated with the catalytic domain of galactose oxidase; Region: E_set_GO_C; cd02851 272560024292 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 24.4, E-value 0.00018 272560024293 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 14.5, E-value 0.048 272560024294 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 21.2, E-value 0.0016 272560024295 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 22.4, E-value 0.00072 272560024296 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 25.0, E-value 0.00011 272560024297 Pfam match to entry PF00652 Ricin_B_lectin, QXW lectin repeat , score 22.0, E-value 0.00092 272560024298 Signal peptide predicted for BPSS1650 by SignalP 2.0 HMM (Signal peptide probability 0.931) with cleavage site probability 0.287 between residues 40 and 41; signal peptide 272560024299 PS00190 Cytochrome c family heme-binding site signature. 272560024300 Signal peptide predicted for BPSS1651 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 30 and 31; signal peptide 272560024301 SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968 272560024302 Cu(I) binding site [ion binding]; other site 272560024303 Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396 272560024304 active site 272560024305 nucleophile elbow; other site 272560024306 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 91.7, E-value 9.5e-25 272560024307 benzoate transport; Region: 2A0115; TIGR00895 272560024308 3 probable transmembrane helices predicted for BPSS1653 by TMHMM2.0 at aa 66-88, 117-139 and 144-166 272560024309 Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124 272560024310 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018 272560024311 Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185 272560024312 FMN-binding pocket [chemical binding]; other site 272560024313 flavin binding motif; other site 272560024314 phosphate binding motif [ion binding]; other site 272560024315 beta-alpha-beta structure motif; other site 272560024316 NAD binding pocket [chemical binding]; other site 272560024317 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560024318 catalytic loop [active] 272560024319 iron binding site [ion binding]; other site 272560024320 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 71.8, E-value 9.6e-19 272560024321 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560024322 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 17.8, E-value 2.4e-06 272560024323 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 40.7, E-value 2.2e-09 272560024324 Pfam match to entry PF00067 p450, Cytochrome P450 , score 55.7, E-value 6.7e-14 272560024325 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 272560024326 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560024327 H+ Antiporter protein; Region: 2A0121; TIGR00900 272560024328 putative substrate translocation pore; other site 272560024329 9 probable transmembrane helices predicted for BPSS1656 by TMHMM2.0 at aa 20-42, 55-74, 84-106, 113-135, 175-197, 229-251, 266-288, 301-323 and 379-401 272560024330 Signal peptide predicted for BPSS1657 by SignalP 2.0 HMM (Signal peptide probability 0.727) with cleavage site probability 0.714 between residues 21 and 22; signal peptide 272560024331 beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098 272560024332 Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933 272560024333 Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915 272560024334 Fibronectin type III-like domain; Region: Fn3-like; pfam14310 272560024335 Pfam match to entry PF00933 Glyco_hydro_3, Glycosyl hydrolase 3 N terminal domain , score 303.8, E-value 1.4e-88 272560024336 Pfam match to entry PF01915 Glyco_hydro_3_C, Glycosyl hydrolase 3 C terminal domain , score 194.9, E-value 8.5e-56 272560024337 Amidase; Region: Amidase; cl11426 272560024338 Protein of unknown function (DUF2778); Region: DUF2778; pfam10908 272560024339 1 probable transmembrane helix predicted for BPSS1661 by TMHMM2.0 at aa 36-58 272560024340 selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512 272560024341 SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171 272560024342 G1 box; other site 272560024343 putative GEF interaction site [polypeptide binding]; other site 272560024344 GTP/Mg2+ binding site [chemical binding]; other site 272560024345 Switch I region; other site 272560024346 G2 box; other site 272560024347 G3 box; other site 272560024348 Switch II region; other site 272560024349 G4 box; other site 272560024350 G5 box; other site 272560024351 selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696 272560024352 This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094 272560024353 Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106 272560024354 Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107 272560024355 Pfam match to entry PF03144 GTP_EFTU_D2, Elongation factor Tu domain 2 , score 49.9, E-value 3.6e-12 272560024356 Pfam match to entry PF00009 GTP_EFTU, Elongation factor Tu GTP binding domain , score 112.2, E-value 6.3e-31 272560024357 PS00301 GTP-binding elongation factors signature. 272560024358 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024359 selenocysteine synthase; Provisional; Region: PRK04311 272560024360 Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390 272560024361 L-seryl-tRNA selenium transferase; Region: SelA; pfam03841 272560024362 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560024363 catalytic residue [active] 272560024364 Pfam match to entry PF03841 SelA, L-seryl-tRNA selenium transferase , score 715.7, E-value 1.4e-212 272560024365 Protein involved in formate dehydrogenase formation; Region: FdhE; pfam04216 272560024366 PS00190 Cytochrome c family heme-binding site signature. 272560024367 Cytochrome b (N-terminus)/b6/petB: Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859 272560024368 4 probable transmembrane helices predicted for BPSS1665 by TMHMM2.0 at aa 21-43, 56-78, 118-140 and 155-177 272560024369 formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582 272560024370 4Fe-4S dicluster domain; Region: Fer4_11; pfam13247 272560024371 Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163 272560024372 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 30.2, E-value 3.2e-06 272560024373 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560024374 Signal peptide predicted for BPSS1668 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.537 between residues 34 and 35; signal peptide 272560024375 formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553 272560024376 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752 272560024377 [4Fe-4S] binding site [ion binding]; other site 272560024378 molybdopterin cofactor binding site; other site 272560024379 Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792 272560024380 molybdopterin cofactor binding site; other site 272560024381 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 129.3, E-value 4.4e-36 272560024382 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score -166.8, E-value 3.2e-07 272560024383 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 68.4, E-value 4.5e-19 272560024384 PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 272560024385 YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259 272560024386 putative active site [active] 272560024387 Pfam match to entry PF02698 DUF218, Uncharacterized ACR, COG1434 , score 9.4, E-value 1.8e-07 272560024388 PS00211 ABC transporters family signature. 272560024389 2 probable transmembrane helices predicted for BPSS1669 by TMHMM2.0 at aa 39-61 and 70-92 272560024390 Signal peptide predicted for BPSS1670 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.460 between residues 27 and 28; signal peptide 272560024391 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560024392 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560024393 substrate binding pocket [chemical binding]; other site 272560024394 membrane-bound complex binding site; other site 272560024395 hinge residues; other site 272560024396 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 88.5, E-value 8.9e-24 272560024397 ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160 272560024398 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560024399 dimer interface [polypeptide binding]; other site 272560024400 conserved gate region; other site 272560024401 putative PBP binding loops; other site 272560024402 ABC-ATPase subunit interface; other site 272560024403 ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126 272560024404 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560024405 Walker A/P-loop; other site 272560024406 ATP binding site [chemical binding]; other site 272560024407 Q-loop/lid; other site 272560024408 ABC transporter signature motif; other site 272560024409 Walker B; other site 272560024410 D-loop; other site 272560024411 H-loop/switch region; other site 272560024412 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 232.9, E-value 3e-67 272560024413 PS00211 ABC transporters family signature. 272560024414 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024415 5 probable transmembrane helices predicted for BPSS1671 by TMHMM2.0 at aa 41-63, 83-105, 112-134, 232-254 and 267-289 272560024416 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 48.4, E-value 1e-11 272560024417 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560024418 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 272560024419 active site 272560024420 non-prolyl cis peptide bond; other site 272560024421 luciferase family oxidoreductase, group 1; Region: oxido_grp_1; TIGR03558 272560024422 Pfam match to entry PF00296 bac_luciferase, Luciferase-like monooxygenase , score 18.0, E-value 1.2e-09 272560024423 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560024424 Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497 272560024425 substrate binding pocket [chemical binding]; other site 272560024426 membrane-bound complex binding site; other site 272560024427 hinge residues; other site 272560024428 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 129.6, E-value 3.8e-36 272560024429 Signal peptide predicted for BPSS1674 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 44 and 45 272560024430 1 probable transmembrane helix predicted for BPSS1674 by TMHMM2.0 at aa 21-43 272560024431 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560024432 Coenzyme A binding pocket [chemical binding]; other site 272560024433 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 48.4, E-value 1e-11 272560024434 ectoine utilization protein EutE; Region: ectoine_eutE; TIGR02994 272560024435 Peptidase M14 Succinylglutamate desuccinylase (ASTE)/aspartoacylase (ASPA)-like; uncharacterized subgroup; Region: M14_ASTE_ASPA_like_2; cd06252 272560024436 putative active site [active] 272560024437 Zn binding site [ion binding]; other site 272560024438 Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631 272560024439 Pfam match to entry PF03631 Ribonuclease_BN, Ribonuclease BN-like family , score 157.3, E-value 1.7e-44 272560024440 6 probable transmembrane helices predicted for BPSS1678 by TMHMM2.0 at aa 41-63, 109-131, 152-174, 184-206, 226-245 and 255-277 272560024441 Signal peptide predicted for BPSS1679 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.985 between residues 49 and 50; signal peptide 272560024442 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560024443 trimer interface [polypeptide binding]; other site 272560024444 eyelet of channel; other site 272560024445 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -35.2, E-value 7e-05 272560024446 DNA-binding proteins similar to HU domains; Region: HU_like; cd13834 272560024447 putative DNA binding site [nucleotide binding]; other site 272560024448 putative dimer interface [polypeptide binding]; other site 272560024449 Pfam match to entry PF00216 Bac_DNA_binding, Bacterial DNA-binding protein , score 33.3, E-value 2.2e-08 272560024450 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560024451 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 24.5, E-value 2.9e-07 272560024452 7 probable transmembrane helices predicted for BPSS1681 by TMHMM2.0 at aa 41-63, 84-106, 162-184, 191-213, 223-245, 252-274 and 284-303 272560024453 Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541 272560024454 active site 272560024455 tetramer interface; other site 272560024456 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 67.8, E-value 1.5e-17 272560024457 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560024458 9 probable transmembrane helices predicted for BPSS1683 by TMHMM2.0 at aa 44-66, 81-103, 134-156, 192-211, 218-237, 242-259, 278-300, 332-354 and 361-383 272560024459 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 34.1, E-value 1.1e-07 272560024460 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560024461 This family is most closely related to the GT1 family of glycosyltransferases. wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804 272560024462 putative ADP-binding pocket [chemical binding]; other site 272560024463 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560024464 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 272560024465 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 138.1, E-value 1.1e-38 272560024466 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 115.6, E-value 6e-32 272560024467 Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244 272560024468 Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326 272560024469 12 probable transmembrane helices predicted for BPSS1685 by TMHMM2.0 at aa 9-31, 41-63, 86-108, 123-145, 165-187, 191-210, 223-241, 307-329, 342-364, 379-401, 421-440 and 445-467 272560024470 Pfam match to entry PF01943 Polysacc_synt, Polysaccharide biosynthesis protein , score 86.1, E-value 4.8e-23 272560024471 Signal peptide predicted for BPSS1686 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.961 between residues 23 and 24; signal peptide 272560024472 PS00018 EF-hand calcium-binding domain. 272560024473 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560024474 9 probable transmembrane helices predicted for BPSS1687 by TMHMM2.0 at aa 38-60, 81-103, 128-150, 157-176, 180-202, 214-233, 248-267, 280-302 and 312-331 272560024475 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score 78.9, E-value 6.8e-21 272560024476 GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089 272560024477 GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260 272560024478 NADP-binding site; other site 272560024479 homotetramer interface [polypeptide binding]; other site 272560024480 substrate binding site [chemical binding]; other site 272560024481 homodimer interface [polypeptide binding]; other site 272560024482 active site 272560024483 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560024484 NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370 272560024485 NAD(P) binding site [chemical binding]; other site 272560024486 active site 272560024487 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 22.1, E-value 9.5e-15 272560024488 Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662 272560024489 CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614 272560024490 homodimer interface [polypeptide binding]; other site 272560024491 substrate-cofactor binding pocket; other site 272560024492 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560024493 catalytic residue [active] 272560024494 Pfam match to entry PF01053 Cys_Met_Meta_PP, Cys/Met metabolism PLP-dependent enzyme , score 651.6, E-value 2.7e-193 272560024495 PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 272560024496 PS00070 Aldehyde dehydrogenases cysteine active site. 272560024497 amidophosphoribosyltransferase; Provisional; Region: PRK09246 272560024498 Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715 272560024499 active site 272560024500 tetramer interface [polypeptide binding]; other site 272560024501 Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223 272560024502 active site 272560024503 Pfam match to entry PF00156 Pribosyltran, Phosphoribosyl transferase domain , score 31.6, E-value 1.2e-06 272560024504 PS00103 Purine/pyrimidine phosphoribosyl transferases signature. 272560024505 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 248.7, E-value 5.2e-72 272560024506 PS00443 Glutamine amidotransferases class-II active site. 272560024507 Colicin V production protein; Region: Colicin_V; pfam02674 272560024508 Pfam match to entry PF02674 Colicin_V, Colicin V production protein , score 103.2, E-value 3.2e-28 272560024509 4 probable transmembrane helices predicted for BPSS1693 by TMHMM2.0 at aa 4-26, 33-55, 65-87 and 107-126 272560024510 Uncharacterized protein conserved in bacteria [Function unknown]; Region: DedD; COG3147 272560024511 Sporulation related domain; Region: SPOR; pfam05036 272560024512 1 probable transmembrane helix predicted for BPSS1694 by TMHMM2.0 at aa 37-55 272560024513 Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285 272560024514 Mur ligase middle domain; Region: Mur_ligase_M; pfam08245 272560024515 Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875 272560024516 Pfam match to entry PF02875 Mur_ligase_C, Mur ligase, glutamate ligase domain , score 22.3, E-value 0.00011 272560024517 Pfam match to entry PF01225 Mur_ligase, Mur ligase, catalytic domain , score 46.0, E-value 5.3e-11 272560024518 PS01011 Folylpolyglutamate synthase signature 1. 272560024519 acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654 272560024520 Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain , score 28.0, E-value 5.1e-08 272560024521 Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724 272560024522 substrate binding site [chemical binding]; other site 272560024523 active site 272560024524 catalytic residues [active] 272560024525 heterodimer interface [polypeptide binding]; other site 272560024526 Pfam match to entry PF00290 trp_syntA, Tryptophan synthase alpha chain , score 355.7, E-value 3.1e-104 272560024527 PS00287 Cysteine proteases inhibitors signature. 272560024528 PS00167 Tryptophan synthase alpha chain signature. 272560024529 DNA methylase; Region: N6_N4_Mtase; pfam01555 272560024530 Pfam match to entry PF01555 N6_N4_Mtase, DNA methylase , score 135.3, E-value 7e-38 272560024531 PS00092 N-6 Adenine-specific DNA methylases signature. 272560024532 PS00228 Tubulin-beta mRNA autoregulation signal. 272560024533 Tryptophan synthase-beta: Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446 272560024534 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560024535 catalytic residue [active] 272560024536 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 430.7, E-value 8.6e-127 272560024537 PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 272560024538 Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405 272560024539 active site 272560024540 Pfam match to entry PF00697 PRAI, N-(5'phosphoribosyl)anthranilate (PRA) isomerase , score 197.7, E-value 1.2e-56 272560024541 tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021 272560024542 Eukaryotic and bacterial pseudouridine synthases similar to E. coli TruA; Region: PseudoU_synth_EcTruA; cd02570 272560024543 dimerization interface 3.5A [polypeptide binding]; other site 272560024544 active site 272560024545 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase , score 116.1, E-value 4.2e-32 272560024546 Pfam match to entry PF01416 PseudoU_synth_1, tRNA pseudouridine synthase , score 101.8, E-value 9e-28 272560024547 FimV C-terminal domain; Region: FimV_Cterm; TIGR03504 272560024548 Signal peptide predicted for BPSS1703 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.444 between residues 22 and 23; signal peptide 272560024549 FimV N-terminal domain; Region: FimV_core; TIGR03505 272560024550 1 probable transmembrane helix predicted for BPSS1703 by TMHMM2.0 at aa 369-391 272560024551 aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598 272560024552 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118 272560024553 Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774 272560024554 Pfam match to entry PF02774 Semialdhyde_dhC, Semialdehyde dehydrogenase, dimerisation domain , score 238.4, E-value 6.4e-69 272560024555 PS01103 Aspartate-semialdehyde dehydrogenase signature. 272560024556 Pfam match to entry PF01118 Semialdhyde_dh, Semialdehyde dehydrogenase, NAD binding domain , score 107.6, E-value 1.6e-29 272560024557 3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772 272560024558 Pfam match to entry PF00180 isodh, Isocitrate/isopropylmalate dehydrogenase , score 652.7, E-value 1.3e-193 272560024559 PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 272560024560 Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577 272560024561 substrate binding site [chemical binding]; other site 272560024562 Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain , score 234.2, E-value 1.2e-67 272560024563 Entericidin EcnA/B family; Region: Entericidin; cl02322 272560024564 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583 272560024565 substrate binding site [chemical binding]; other site 272560024566 ligand binding site [chemical binding]; other site 272560024567 Pfam match to entry PF00330 aconitase, Aconitase (aconitate hydratase) , score 810.1, E-value 5.4e-241 272560024568 PS01244 Aconitase signature 2. 272560024569 PS00450 Aconitase signature 1. 272560024570 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 272560024571 active site 272560024572 non-prolyl cis peptide bond; other site 272560024573 Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967 272560024574 metal binding site [ion binding]; metal-binding site 272560024575 nucleotidyl binding site; other site 272560024576 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560024577 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560024578 putative DNA binding site [nucleotide binding]; other site 272560024579 putative Zn2+ binding site [ion binding]; other site 272560024580 AsnC family; Region: AsnC_trans_reg; pfam01037 272560024581 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 178.1, E-value 9.4e-51 272560024582 PS00519 Bacterial regulatory proteins, asnC family signature. 272560024583 Predicted helix-turn-helix motif with score 1262.000, SD 3.49 at aa 47-68, sequence ITNAELARAVNLSPTPCFNRVR 272560024584 2-oxoacid dehydrogenase subunit E1; Provisional; Region: PRK13012 272560024585 Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017 272560024586 dimer interface [polypeptide binding]; other site 272560024587 TPP-binding site [chemical binding]; other site 272560024588 Transketolase, pyrimidine binding domain; Region: Transket_pyr; smart00861 272560024589 Pfam match to entry PF00456 transketolase, Transketolase, thiamine diphosphate binding domain , score -135.7, E-value 2.4e-07 272560024590 Protein of unknown function (DUF1479); Region: DUF1479; pfam07350 272560024591 This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_19; cd07262 272560024592 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 22.0, E-value 3.5e-06 272560024593 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560024594 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560024595 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560024596 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 32.7, E-value 5.6e-07 272560024597 Predicted helix-turn-helix motif with score 1307.000, SD 3.64 at aa 201-222, sequence LRVAELAALAHLSERSLQRRFA 272560024598 PS00041 Bacterial regulatory proteins, araC family signature. 272560024599 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 22.9, E-value 0.00048 272560024600 Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114 272560024601 Citrate synthase [Energy production and conversion]; Region: GltA; COG0372 272560024602 dimer interface [polypeptide binding]; other site 272560024603 active site 272560024604 citrylCoA binding site [chemical binding]; other site 272560024605 NADH binding [chemical binding]; other site 272560024606 cationic pore residues; other site 272560024607 oxalacetate/citrate binding site [chemical binding]; other site 272560024608 coenzyme A binding site [chemical binding]; other site 272560024609 catalytic triad [active] 272560024610 Pfam match to entry PF00285 citrate_synt, Citrate synthase , score 756.0, E-value 1e-224 272560024611 PS00480 Citrate synthase signature. 272560024612 Flavinator of succinate dehydrogenase; Region: Sdh5; pfam03937 272560024613 Pfam match to entry PF03937 DUF339, Domain of unknown function (DUF339) , score 48.3, E-value 1.1e-11 272560024614 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 272560024615 succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950 272560024616 4Fe-4S dicluster domain; Region: Fer4_17; pfam13534 272560024617 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560024618 succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07057 272560024619 L-aspartate oxidase; Provisional; Region: PRK06175 272560024620 Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910 272560024621 Pfam match to entry PF02910 succ_DH_flav_C, Fumarate reductase/succinate dehydrogenase flavoprotein C-terminal domain , score 234.0, E-value 1.4e-67 272560024622 Pfam match to entry PF00890 FAD_binding_2, FAD binding domain , score 653.1, E-value 9.8e-194 272560024623 PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 272560024624 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494 272560024625 SdhC subunit interface [polypeptide binding]; other site 272560024626 proximal heme binding site [chemical binding]; other site 272560024627 cardiolipin binding site; other site 272560024628 Iron-sulfur protein interface; other site 272560024629 proximal quinone binding site [chemical binding]; other site 272560024630 3 probable transmembrane helices predicted for BPSS1719 by TMHMM2.0 at aa 23-45, 66-88 and 98-120 272560024631 Pfam match to entry PF01127 Sdh_cyt, Succinate dehydrogenase cytochrome b subunit , score -38.7, E-value 0.023 272560024632 Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499 272560024633 Iron-sulfur protein interface; other site 272560024634 proximal quinone binding site [chemical binding]; other site 272560024635 SdhD (CybS) interface [polypeptide binding]; other site 272560024636 proximal heme binding site [chemical binding]; other site 272560024637 3 probable transmembrane helices predicted for BPSS1720 by TMHMM2.0 at aa 7-29, 44-66 and 90-112 272560024638 Pfam match to entry PF01127 Sdh_cyt, Succinate dehydrogenase cytochrome b subunit , score 65.4, E-value 7.9e-17 272560024639 Transcriptional regulators [Transcription]; Region: PhnF; COG2188 272560024640 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560024641 DNA-binding site [nucleotide binding]; DNA binding site 272560024642 The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866 272560024643 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 80.6, E-value 2.1e-21 272560024644 Predicted helix-turn-helix motif with score 1103.000, SD 2.94 at aa 59-80, sequence PSEVELAGRYKVSQGTVRKAID 272560024645 malate dehydrogenase; Provisional; Region: PRK05442 272560024646 Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338 272560024647 NAD(P) binding site [chemical binding]; other site 272560024648 dimer interface [polypeptide binding]; other site 272560024649 malate binding site [chemical binding]; other site 272560024650 Pfam match to entry PF00056 ldh, lactate/malate dehydrogenase, NAD binding domain , score 190.6, E-value 1.6e-54 272560024651 Pfam match to entry PF02866 ldh_C, lactate/malate dehydrogenase, alpha/beta C-terminal domain , score 122.0, E-value 7.4e-34 272560024652 HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231 272560024653 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024654 Signal peptide predicted for BPSS1724 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 26 and 27; signal peptide 272560024655 1 probable transmembrane helix predicted for BPSS1724 by TMHMM2.0 at aa 4-26 272560024656 2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425 272560024657 Pfam match to entry PF03972 MmgE_PrpD, MmgE/PrpD family , score 778.5, E-value 1.7e-231 272560024658 aconitate hydratase; Provisional; Region: acnA; PRK12881 272560024659 Aconitase A catalytic domain; Region: AcnA_IRP; cd01586 272560024660 substrate binding site [chemical binding]; other site 272560024661 ligand binding site [chemical binding]; other site 272560024662 Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580 272560024663 substrate binding site [chemical binding]; other site 272560024664 Pfam match to entry PF00330 aconitase, Aconitase (aconitate hydratase) , score 725.4, E-value 1.6e-215 272560024665 PS00450 Aconitase signature 1. 272560024666 PS01244 Aconitase signature 2. 272560024667 Pfam match to entry PF00694 Aconitase_C, Aconitase C-terminal domain , score 205.8, E-value 4.3e-59 272560024668 haemagglutination activity domain; Region: Haemagg_act; pfam05860 272560024669 Inositol polyphosphate kinase; Region: IPK; cl12283 272560024670 1 probable transmembrane helix predicted for BPSS1727 by TMHMM2.0 at aa 49-71 272560024671 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 272560024672 Signal peptide predicted for BPSS1728 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.776 between residues 23 and 24; signal peptide 272560024673 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 272560024674 Pfam match to entry PF03865 HlyB, Hemolysin activator HlyB , score -106.4, E-value 1.1e-10 272560024675 Probable gene remnant. Similar to the N-terminal regions of Xylella fastidiosa IS1327 transposase Tnp SWALL:Q87BW4 (EMBL:AE012558) (188 aa) fasta scores: E(): 4.3e-05, 40.22% id in 87 aa, and to Pantoea agglomerans IS1327 containing a transposase TnpA SWALL:P94785 (EMBL:X87144) (234 aa) fasta scores: E(): 0.00022, 39.08% id in 87 aa; transposase (fragment) 272560024676 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560024677 Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010 272560024678 Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442 272560024679 Cytochrome c [Energy production and conversion]; Region: COG3258 272560024680 Cytochrome c; Region: Cytochrom_C; pfam00034 272560024681 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 3.4, E-value 0.012 272560024682 PS00190 Cytochrome c family heme-binding site signature. 272560024683 PS00190 Cytochrome c family heme-binding site signature. 272560024684 PS00190 Cytochrome c family heme-binding site signature. 272560024685 PS00190 Cytochrome c family heme-binding site signature. 272560024686 Pfam match to entry PF00034 cytochrome_c, Cytochrome c , score 0.1, E-value 0.027 272560024687 PS00190 Cytochrome c family heme-binding site signature. 272560024688 Protein of Unknown function (DUF2784); Region: DUF2784; pfam10861 272560024689 3 probable transmembrane helices predicted for BPSS1730 by TMHMM2.0 at aa 15-37, 44-61 and 96-115 272560024690 Common central domain of tyrosinase; Region: Tyrosinase; pfam00264 272560024691 Pfam match to entry PF00264 tyrosinase, Common central domain of tyrosinase , score -17.9, E-value 3e-10 272560024692 PS00498 Tyrosinase and hemocyanins CuB-binding region signature. 272560024693 4 probable transmembrane helices predicted for BPSS1732 by TMHMM2.0 at aa 20-42, 104-126, 139-161 and 165-187 272560024694 1 probable transmembrane helix predicted for BPSS1733 by TMHMM2.0 at aa 4-21 272560024695 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 272560024696 peptidase domain interface [polypeptide binding]; other site 272560024697 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 272560024698 active site 272560024699 catalytic triad [active] 272560024700 calcium binding site [ion binding]; other site 272560024701 PS00138 Serine proteases, subtilase, serine active site. 272560024702 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560024703 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560024704 dimer interface [polypeptide binding]; other site 272560024705 conserved gate region; other site 272560024706 putative PBP binding loops; other site 272560024707 ABC-ATPase subunit interface; other site 272560024708 6 probable transmembrane helices predicted for BPSS1735 by TMHMM2.0 at aa 21-43, 81-103, 115-137, 147-169, 190-212 and 244-266 272560024709 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 57.1, E-value 2.4e-14 272560024710 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560024711 PS00430 TonB-dependent receptor proteins signature 1. 272560024712 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560024713 dimer interface [polypeptide binding]; other site 272560024714 conserved gate region; other site 272560024715 putative PBP binding loops; other site 272560024716 ABC-ATPase subunit interface; other site 272560024717 6 probable transmembrane helices predicted for BPSS1736 by TMHMM2.0 at aa 32-54, 208-230, 242-264, 291-313, 346-368 and 388-410 272560024718 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 43.4, E-value 3.3e-10 272560024719 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560024720 Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687 272560024721 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 51.3, E-value 1.4e-12 272560024722 Signal peptide predicted for BPSS1737 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 46 and 47 272560024723 ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842 272560024724 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560024725 Walker A/P-loop; other site 272560024726 ATP binding site [chemical binding]; other site 272560024727 Q-loop/lid; other site 272560024728 ABC transporter signature motif; other site 272560024729 Walker B; other site 272560024730 D-loop; other site 272560024731 H-loop/switch region; other site 272560024732 TOBE domain; Region: TOBE_2; pfam08402 272560024733 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 206.2, E-value 3.3e-59 272560024734 PS00211 ABC transporters family signature. 272560024735 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024736 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167 272560024737 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560024738 DNA-binding site [nucleotide binding]; DNA binding site 272560024739 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560024740 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560024741 homodimer interface [polypeptide binding]; other site 272560024742 catalytic residue [active] 272560024743 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 49.6, E-value 4.6e-12 272560024744 lipase chaperone; Provisional; Region: PRK01294 272560024745 Proteobacterial lipase chaperone protein; Region: Lipase_chap; pfam03280 272560024746 Pfam match to entry PF03280 Lipase_chap, Proteobacterial lipase chaperone protein , score 359.2, E-value 2.9e-105 272560024747 1 probable transmembrane helix predicted for BPSS1740 by TMHMM2.0 at aa 7-29 272560024748 Signal peptide predicted for BPSS1741 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.473 between residues 40 and 41; signal peptide 272560024749 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 272560024750 alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561 272560024751 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 91.7, E-value 9.7e-25 272560024752 PS00120 Lipases, serine active site. 272560024753 TonB-dependent copper receptor; Region: TonB-copper; TIGR01778 272560024754 TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347 272560024755 N-terminal plug; other site 272560024756 ligand-binding site [chemical binding]; other site 272560024757 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 58.3, E-value 1e-14 272560024758 Signal peptide predicted for BPSS1743 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.507 between residues 34 and 35; signal peptide 272560024759 Protein of unknown function (DUF2946); Region: DUF2946; pfam11162 272560024760 Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038 272560024761 4 probable transmembrane helices predicted for BPSS1744 by TMHMM2.0 at aa 15-33, 46-68, 83-105 and 145-167 272560024762 6 probable transmembrane helices predicted for BPSS1745 by TMHMM2.0 at aa 7-27, 42-64, 77-99, 109-127, 140-158 and 173-195 272560024763 Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118 272560024764 Peptidase family M23; Region: Peptidase_M23; pfam01551 272560024765 Pfam match to entry PF01551 Peptidase_M37, Peptidase M23/M37 , score 90.9, E-value 1.7e-24 272560024766 PS00626 Regulator of chromosome condensation (RCC1) signature 2. 272560024767 Pfam match to entry PF01476 LysM, LysM domain , score 46.1, E-value 5.1e-11 272560024768 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560024769 Cupin domain; Region: Cupin_2; cl17218 272560024770 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560024771 1 probable transmembrane helix predicted for BPSS1748 by TMHMM2.0 at aa 20-42 272560024772 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560024773 6-phosphogluconate dehydrogenase; Validated; Region: PRK09287 272560024774 6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393 272560024775 Pfam match to entry PF00393 6PGD, 6-phosphogluconate dehydrogenase, C-terminal domain , score 732.2, E-value 1.5e-217 272560024776 PS00461 6-phosphogluconate dehydrogenase signature. 272560024777 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score 389.3, E-value 2.4e-114 272560024778 SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500 272560024779 Protein of unknown function (DUF938); Region: DUF938; pfam06080 272560024780 NAD-dependent deacetylase; Provisional; Region: PRK05333 272560024781 Pfam match to entry PF02146 SIR2, Sir2 family , score 171.9, E-value 7.1e-49 272560024782 Purine-cytosine permease and related proteins [Nucleotide transport and metabolism]; Region: CodB; COG1457 272560024783 Na binding site [ion binding]; other site 272560024784 12 probable transmembrane helices predicted for BPSS1752 by TMHMM2.0 at aa 34-56, 61-83, 100-119, 134-156, 163-185, 195-217, 238-260, 275-297, 330-352, 357-379, 400-422 and 437-454 272560024785 Pfam match to entry PF02133 Transp_cyt_pur, Permease for cytosine/purines, uracil, thiamine, allantoin , score 134.0, E-value 1.8e-37 272560024786 Pfam match to entry PF01787 Ilar_coat, Ilarvirus coat protein , score -71.7, E-value 0.17 272560024787 Low GC content region (50.77%) 272560024788 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560024789 S-adenosylmethionine binding site [chemical binding]; other site 272560024790 Methyltransferase domain; Region: Methyltransf_31; pfam13847 272560024791 Predicted acyltransferases [Lipid metabolism]; Region: COG1835 272560024792 9 probable transmembrane helices predicted for BPSS1754 by TMHMM2.0 at aa 41-63, 84-101, 123-145, 152-174, 179-201, 222-241, 267-289, 302-324 and 339-358 272560024793 Pfam match to entry PF01757 Acyl_transf_3, Acyltransferase , score -80.9, E-value 0.012 272560024794 RNA polymerase sigma factor RpoD; Validated; Region: PRK05658 272560024795 Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979 272560024796 Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140 272560024797 Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546 272560024798 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560024799 Sigma-70 region 3; Region: Sigma70_r3; pfam04539 272560024800 Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171 272560024801 DNA binding residues [nucleotide binding] 272560024802 PS00716 Sigma-70 factors family signature 2. 272560024803 Predicted helix-turn-helix motif with score 1917.000, SD 5.72 at aa 637-658, sequence HTLEEVGKQFDVTRERIRQIEA 272560024804 PS00715 Sigma-70 factors family signature 1. 272560024805 Pfam match to entry PF00140 sigma70_r1_2, Sigma-70 factor, region 1.2 , score 66.1, E-value 5e-17 272560024806 Pfam match to entry PF03979 sigma70_r1_1, Sigma-70 factor, region 1.1 , score 149.1, E-value 4.9e-42 272560024807 DNA primase; Validated; Region: dnaG; PRK05667 272560024808 CHC2 zinc finger; Region: zf-CHC2; pfam01807 272560024809 DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275 272560024810 TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364 272560024811 active site 272560024812 metal binding site [ion binding]; metal-binding site 272560024813 interdomain interaction site; other site 272560024814 DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410 272560024815 DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; cl07879 272560024816 Pfam match to entry PF01751 Toprim, Toprim domain , score 72.1, E-value 7.4e-19 272560024817 Pfam match to entry PF01807 zf-CHC2, CHC2 zinc finger , score 206.7, E-value 2.3e-59 272560024818 Yqey-like protein; Region: YqeY; pfam09424 272560024819 Pfam match to entry PF02637 DUF186, GatB/Yqey domain , score 32.5, E-value 6.3e-07 272560024820 30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270 272560024821 Pfam match to entry PF01165 Ribosomal_S21, Ribosomal protein S21 , score 117.4, E-value 1.8e-32 272560024822 Signal peptide predicted for BPSS1759 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.977 between residues 22 and 23; signal peptide 272560024823 HI0933-like protein; Region: HI0933_like; pfam03486 272560024824 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560024825 Pfam match to entry PF03486 HI0933_like, HI0933-like protein , score 457.1, E-value 9.4e-135 272560024826 UGMP family protein; Validated; Region: PRK09604 272560024827 Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884 272560024828 Pfam match to entry PF00814 Peptidase_M22, Glycoprotease , score 534.2, E-value 5.8e-158 272560024829 putative GTP cyclohydrolase; Provisional; Region: PRK13674 272560024830 Pfam match to entry PF02649 DUF198, Uncharacterized ACR, COG1469 , score 144.3, E-value 1.4e-40 272560024831 1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444 272560024832 Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007 272560024833 TPP-binding site; other site 272560024834 Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033 272560024835 PYR/PP interface [polypeptide binding]; other site 272560024836 dimer interface [polypeptide binding]; other site 272560024837 TPP binding site [chemical binding]; other site 272560024838 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 272560024839 Pfam match to entry PF02780 transketolase_C, Transketolase, C-terminal domain , score 118.3, E-value 9.5e-33 272560024840 Pfam match to entry PF02779 transket_pyr, Transketolase, pyridine binding domain , score 229.7, E-value 2.7e-66 272560024841 PS00802 Transketolase signature 2. 272560024842 PS00801 Transketolase signature 1. 272560024843 Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685 272560024844 substrate binding pocket [chemical binding]; other site 272560024845 chain length determination region; other site 272560024846 substrate-Mg2+ binding site; other site 272560024847 catalytic residues [active] 272560024848 aspartate-rich region 1; other site 272560024849 active site lid residues [active] 272560024850 aspartate-rich region 2; other site 272560024851 Pfam match to entry PF00348 polyprenyl_synt, Polyprenyl synthetase , score 288.0, E-value 7.8e-84 272560024852 PS00444 Polyprenyl synthetases signature 2. 272560024853 PS00723 Polyprenyl synthetases signature 1. 272560024854 exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977 272560024855 Pfam match to entry PF02609 Exonuc_VII_S, Exonuclease VII small subunit , score 70.5, E-value 2.3e-18 272560024856 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638 272560024857 Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469 272560024858 [2Fe-2S] cluster binding site [ion binding]; other site 272560024859 C-terminal catalytic domain of the oxygenase alpha subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C; cd00680 272560024860 alpha subunit interface [polypeptide binding]; other site 272560024861 active site 272560024862 substrate binding site [chemical binding]; other site 272560024863 Fe binding site [ion binding]; other site 272560024864 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 68.4, E-value 9.8e-18 272560024865 Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897 272560024866 Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448 272560024867 active site residue [active] 272560024868 Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449 272560024869 active site residue [active] 272560024870 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 44.0, E-value 2.2e-10 272560024871 PS00380 Rhodanese signature 1. 272560024872 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 56.7, E-value 3.4e-14 272560024873 PS00340 Growth factor and cytokines receptors family signature 2. 272560024874 Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412 272560024875 Pfam match to entry PF01738 DLH, Dienelactone hydrolase , score 259.2, E-value 3.7e-75 272560024876 Predicted membrane protein [Function unknown]; Region: COG4655 272560024877 Putative Tad-like Flp pilus-assembly; Region: Tad_C; pfam09977 272560024878 1 probable transmembrane helix predicted for BPSS1768 by TMHMM2.0 at aa 33-55 272560024879 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252 272560024880 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560024881 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 135.7, E-value 5.4e-38 272560024882 DNA polymerase I; Provisional; Region: PRK05755 272560024883 PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859 272560024884 active site 272560024885 metal binding site 1 [ion binding]; metal-binding site 272560024886 putative 5' ssDNA interaction site; other site 272560024887 metal binding site 3; metal-binding site 272560024888 metal binding site 2 [ion binding]; metal-binding site 272560024889 H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898 272560024890 putative DNA binding site [nucleotide binding]; other site 272560024891 putative metal binding site [ion binding]; other site 272560024892 DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139 272560024893 active site 272560024894 catalytic site [active] 272560024895 substrate binding site [chemical binding]; other site 272560024896 Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637 272560024897 active site 272560024898 DNA binding site [nucleotide binding] 272560024899 catalytic site [active] 272560024900 Pfam match to entry PF00476 DNA_pol_A, DNA polymerase A , score 660.9, E-value 4.4e-196 272560024901 PS00447 DNA polymerase A signature. 272560024902 Pfam match to entry PF01612 3_5_exonuclease, 3'-5' exonuclease , score 144.9, E-value 9.5e-41 272560024903 Pfam match to entry PF01367 5_3_exonuclease, 5'-3' exonuclease, C-terminal SAM fold , score 109.9, E-value 3.2e-30 272560024904 Pfam match to entry PF02739 5_3_exonuc_N, 5'-3' exonuclease, N-terminal resolvase-like domain , score 274.7, E-value 8.1e-80 272560024905 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 272560024906 Pfam match to entry PF03641 Lysine_decarbox, Lysine decarboxylase , score 183.1, E-value 3e-52 272560024907 Signal peptide predicted for BPSS1772 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 23 and 24; signal peptide 272560024908 2 probable transmembrane helices predicted for BPSS1772 by TMHMM2.0 at aa 5-26 and 36-58 272560024909 Uncharacterized conserved protein [Function unknown]; Region: COG1683 272560024910 Low GC content region (53.2%) 272560024911 Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cd00190 272560024912 Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365 272560024913 Gene remnant. Similar to parts of Xanthomonas axonopodis phage-related tail protein S or xac2653 SWALL:Q8PJ88 (EMBL:AE011905) (148 aa) fasta scores: E(): 0.065, 43.18% id in 44 aa, and to Bacteriophage phi CTX ORF14 SWALL:Q9ZXL2 (EMBL:AB008550) (156 aa) fasta scores: E(): 0.5, 39.21% id in 51 aa; phage-related tail protein (fragment) 272560024914 Gene remnant. Similar to parts of Bacteriophage P2 presumed portal vertex protein Q SWALL:VPQ_BPP2 (SWALL:P25480) (344 aa) fasta scores: E(): 3.5e-19, 56.32% id in 87 aa, and of Salmonella typhi probable capsid portal protein sty4628 SWALL:Q8Z1E6 (EMBL:AL627283) (348 aa) fasta scores: E(): 4.2e-18, 53.4% id in 88 aa; phage capsid related protein (fragment) 272560024915 Gene remnant. Similar to the C-terminal regions of Bacteriophage HK022 integrase Int SWALL:VINT_BPHK0 (SWALL:P16407) (357 aa) fasta scores: E(): 0.21, 27.98% id in 218 aa, and Bordetella bronchiseptica integrase SWALL:Q7WLT4 (EMBL:BX640442) (319 aa) fasta scores: E(): 0.0062, 35.21% id in 213 aa; integrase (fragment) 272560024916 Pfam match to entry PF00589 Phage_integrase, Phage integrase , score 26.0, E-value 2.6e-07 272560024917 PS00589 PTS HPR component serine phosphorylation site signature. 272560024918 AMP nucleosidase; Provisional; Region: PRK08292 272560024919 Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423 272560024920 Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775 272560024921 Pfam match to entry PF01048 PNP_UDP_1, Phosphorylase , score 128.4, E-value 8.8e-36 272560024922 PS00018 EF-hand calcium-binding domain. 272560024923 Signal peptide predicted for BPSS1778 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.959 between residues 21 and 22; signal peptide 272560024924 3,4-dihydroxyphenylacetate 2,3-dioxygenase; Region: HpaD; TIGR02295 272560024925 Homoserine Kinase, type II. Homoserine kinase is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs), RIO kinases, actin-fragmin kinase (AFK), and...; Region: HomoserineK_II; cd05153 272560024926 Phosphotransferase enzyme family; Region: APH; pfam01636 272560024927 putative active site [active] 272560024928 putative substrate binding site [chemical binding]; other site 272560024929 ATP binding site [chemical binding]; other site 272560024930 Pfam match to entry PF01636 APH, Phosphotransferase enzyme family , score 69.5, E-value 4.5e-18 272560024931 6 probable transmembrane helices predicted for BPSS1780 by TMHMM2.0 at aa 21-43, 47-69, 98-120, 148-170, 199-221 and 225-247 272560024932 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560024933 helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347 272560024934 putative DNA binding site [nucleotide binding]; other site 272560024935 putative Zn2+ binding site [ion binding]; other site 272560024936 Pfam match to entry PF01047 MarR, MarR family , score 89.6, E-value 4.1e-24 272560024937 peroxiredoxin, Ohr subfamily; Region: organ_hyd_perox; TIGR03561 272560024938 Pfam match to entry PF02566 OsmC, OsmC-like protein , score 141.3, E-value 1.1e-39 272560024939 Protein of unknown function (DUF3563); Region: DUF3563; pfam12086 272560024940 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560024941 PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474 272560024942 active site 272560024943 6 probable transmembrane helices predicted for BPSS1785 by TMHMM2.0 at aa 10-32, 39-61, 71-93, 100-122, 127-149 and 156-178 272560024944 Pfam match to entry PF01569 PAP2, PAP2 superfamily , score 38.3, E-value 1.1e-08 272560024945 ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725 272560024946 1 probable transmembrane helix predicted for BPSS1786 by TMHMM2.0 at aa 50-72 272560024947 Pfam match to entry PF03697 UPF0100, Uncharacterised protein family (UPF0100) , score -70.9, E-value 5.6e-07 272560024948 ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555 272560024949 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560024950 dimer interface [polypeptide binding]; other site 272560024951 conserved gate region; other site 272560024952 putative PBP binding loops; other site 272560024953 ABC-ATPase subunit interface; other site 272560024954 5 probable transmembrane helices predicted for BPSS1787 by TMHMM2.0 at aa 15-34, 47-67, 82-104, 132-154 and 193-215 272560024955 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 80.5, E-value 2.3e-21 272560024956 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560024957 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560024958 thiamine ABC transporter, ATP-binding protein; Region: thiQ; TIGR01277 272560024959 Walker A/P-loop; other site 272560024960 ATP binding site [chemical binding]; other site 272560024961 Q-loop/lid; other site 272560024962 ABC transporter signature motif; other site 272560024963 Walker B; other site 272560024964 D-loop; other site 272560024965 H-loop/switch region; other site 272560024966 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 186.3, E-value 3.2e-53 272560024967 PS00017 ATP/GTP-binding site motif A (P-loop). 272560024968 PS00211 ABC transporters family signature. 272560024969 N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549 272560024970 TOBE domain; Region: TOBE; cl01440 272560024971 TOBE domain; Region: TOBE; cl01440 272560024972 Pfam match to entry PF03459 TOBE, TOBE domain , score 60.6, E-value 2.1e-15 272560024973 Pfam match to entry PF03459 TOBE, TOBE domain , score 64.1, E-value 1.9e-16 272560024974 Pfam match to entry PF02573 HTH_9, N-terminal HTH domain of molybdenum-binding protein , score 152.1, E-value 6.5e-43 272560024975 The CHAD domain is an alpha-helical domain functionally associated with some members of the adenylate cyclase family; Region: CHAD; smart00880 272560024976 4-Oxalocrotonate Tautomerase: Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cl00235 272560024977 Tautomerase enzyme; Region: Tautomerase_2; pfam14552 272560024978 dimer interface [polypeptide binding]; other site 272560024979 hexamer interface [polypeptide binding]; other site 272560024980 active site 2 [active] 272560024981 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560024982 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560024983 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560024984 dimerization interface [polypeptide binding]; other site 272560024985 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 78.4, E-value 9.6e-21 272560024986 Predicted helix-turn-helix motif with score 1595.000, SD 4.62 at aa 19-40, sequence ASFTRAADALGTTQSAVSLKLK 272560024987 PS00044 Bacterial regulatory proteins, lysR family signature. 272560024988 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 91.7, E-value 9.3e-25 272560024989 Signal peptide predicted for BPSS1793 by SignalP 2.0 HMM (Signal peptide probability 0.947) with cleavage site probability 0.591 between residues 44 and 45 272560024990 Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697 272560024991 EamA-like transporter family; Region: EamA; pfam00892 272560024992 EamA-like transporter family; Region: EamA; pfam00892 272560024993 10 probable transmembrane helices predicted for BPSS1793 by TMHMM2.0 at aa 26-48, 58-80, 93-115, 120-142, 149-171, 176-195, 202-224, 234-256, 263-285 and 289-311 272560024994 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 60.1, E-value 3.1e-15 272560024995 Pfam match to entry PF00892 DUF6, Integral membrane protein DUF6 , score 69.0, E-value 6.7e-18 272560024996 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560024997 dimer interface [polypeptide binding]; other site 272560024998 phosphorylation site [posttranslational modification] 272560024999 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518 272560025000 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 31.8, E-value 1e-06 272560025001 Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253 272560025002 Signal peptide predicted for BPSS1795 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.936 between residues 22 and 23; signal peptide 272560025003 Domain of unknown function DUF21; Region: DUF21; pfam01595 272560025004 This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590 272560025005 Transporter associated domain; Region: CorC_HlyC; smart01091 272560025006 Pfam match to entry PF01595 DUF21, Domain of unknown function DUF21 , score 183.5, E-value 2.2e-52 272560025007 4 probable transmembrane helices predicted for BPSS1795 by TMHMM2.0 at aa 5-27, 65-87, 102-124 and 136-158 272560025008 Pfam match to entry PF00571 CBS, CBS domain , score 31.3, E-value 1.5e-06 272560025009 Pfam match to entry PF00571 CBS, CBS domain , score 28.3, E-value 1.2e-05 272560025010 Pfam match to entry PF03471 CorC_HlyC, Transporter associated domain , score 62.3, E-value 6.6e-16 272560025011 Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564 272560025012 thiamine phosphate binding site [chemical binding]; other site 272560025013 active site 272560025014 pyrophosphate binding site [ion binding]; other site 272560025015 N-terminal Early set domain associated with the catalytic domain of Maltooligosyl trehalose trehalohydrolase (also called Glycosyltrehalose trehalohydrolase) and similar proteins; Region: E_set_MTHase_like_N; cd02853 272560025016 Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893 272560025017 active site 272560025018 catalytic site [active] 272560025019 Domain of unknown function (DUF3459); Region: DUF3459; pfam11941 272560025020 Pfam match to entry PF02922 isoamylase_N, Isoamylase N-terminal domain , score 41.8, E-value 9.8e-10 272560025021 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560025022 S-adenosylmethionine binding site [chemical binding]; other site 272560025023 Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600 272560025024 DNA binding residues [nucleotide binding] 272560025025 This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333 272560025026 putative deacylase active site [active] 272560025027 Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809 272560025028 FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070 272560025029 active site 272560025030 substrate binding site [chemical binding]; other site 272560025031 FMN binding site [chemical binding]; other site 272560025032 putative catalytic residues [active] 272560025033 Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase , score 458.6, E-value 3.4e-135 272560025034 PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 272560025035 Homeodomain-like domain; Region: HTH_23; pfam13384 272560025036 Winged helix-turn helix; Region: HTH_29; pfam13551 272560025037 Winged helix-turn helix; Region: HTH_33; pfam13592 272560025038 Predicted helix-turn-helix motif with score 1901.000, SD 5.66 at aa 35-56, sequence MPQADVARRLVVSRQSVCRWAK 272560025039 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560025040 Signal peptide predicted for BPSS1802 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.550 between residues 29 and 30; signal peptide 272560025041 6 probable transmembrane helices predicted for BPSS1802 by TMHMM2.0 at aa 5-27, 42-64, 69-91, 111-133, 145-164 and 174-196 272560025042 AraC-like ligand binding domain; Region: AraC_binding; pfam02311 272560025043 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560025044 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560025045 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 18.7, E-value 0.0092 272560025046 Predicted helix-turn-helix motif with score 988.000, SD 2.55 at aa 189-210, sequence ISMDALEHASGLDRWTIARQFR 272560025047 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 32.0, E-value 8.7e-07 272560025048 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560025049 Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280 272560025050 6 probable transmembrane helices predicted for BPSS1805 by TMHMM2.0 at aa 5-27, 37-59, 66-83, 98-120, 133-155 and 170-192 272560025051 Pfam match to entry PF01810 LysE, LysE type translocator , score 26.9, E-value 1.5e-07 272560025052 Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917 272560025053 Pfam match to entry PF00190 Cupin, Cupin , score -10.9, E-value 0.0022 272560025054 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195 272560025055 4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943 272560025056 active site 272560025057 catalytic residues [active] 272560025058 metal binding site [ion binding]; metal-binding site 272560025059 DmpG-like communication domain; Region: DmpG_comm; pfam07836 272560025060 Predicted helix-turn-helix motif with score 1197.000, SD 3.26 at aa 287-308, sequence PHIQKAAQEFGVNEFELYKRLA 272560025061 Pfam match to entry PF00682 HMGL-like, HMGL-like , score 188.2, E-value 8.8e-54 272560025062 acetaldehyde dehydrogenase (acetylating); Region: ac_ald_DH_ac; TIGR03215 272560025063 Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118 272560025064 Prokaryotic acetaldehyde dehydrogenase, dimerization; Region: AcetDehyd-dimer; pfam09290 272560025065 Pfam match to entry PF02396 Acetylald_DH, Acetaldehyde dehydrogenase , score 296.7, E-value 1.9e-86 272560025066 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560025067 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560025068 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 180.9, E-value 1.3e-51 272560025069 branched-chain amino acid aminotransferase; Validated; Region: PRK06606 272560025070 homodimer interface [polypeptide binding]; other site 272560025071 substrate-cofactor binding pocket; other site 272560025072 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560025073 catalytic residue [active] 272560025074 Pfam match to entry PF01063 aminotran_4, Aminotransferase class IV , score 294.5, E-value 8.7e-86 272560025075 PS00770 Aminotransferases class-IV signature. 272560025076 Demethylmenaquinone methyltransferase; Region: Methyltransf_6; cl00480 272560025077 Predicted thioesterase involved in non-ribosomal peptide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: GrsT; COG3208 272560025078 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560025079 Pfam match to entry PF00975 Thioesterase, Thioesterase domain , score 193.7, E-value 1.8e-55 272560025080 Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; cl17312 272560025081 Phosphopantetheine attachment site; Region: PP-binding; pfam00550 272560025082 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 51.5, E-value 1.2e-12 272560025083 PS00012 Phosphopantetheine attachment site. 272560025084 The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930 272560025085 amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733 272560025086 acyl-activating enzyme (AAE) consensus motif; other site 272560025087 AMP binding site [chemical binding]; other site 272560025088 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 415.9, E-value 2.4e-122 272560025089 1 probable transmembrane helix predicted for BPSS1815 by TMHMM2.0 at aa 64-83 272560025090 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560025091 dimerization interface [polypeptide binding]; other site 272560025092 putative DNA binding site [nucleotide binding]; other site 272560025093 putative Zn2+ binding site [ion binding]; other site 272560025094 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 35.6, E-value 7.2e-08 272560025095 Putative hydrophobic ligand-binding SRPBCC domain of an uncharacterized subgroup of CalC- and Aha1-like proteins; Region: SRPBCC_CalC_Aha1-like_5; cd08898 272560025096 putative hydrophobic ligand binding site [chemical binding]; other site 272560025097 Protein of unknown function (DUF1345); Region: DUF1345; pfam07077 272560025098 5 probable transmembrane helices predicted for BPSS1818 by TMHMM2.0 at aa 13-32, 36-58, 79-101, 116-138 and 194-216 272560025099 metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995 272560025100 active site 272560025101 metal binding site [ion binding]; metal-binding site 272560025102 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 43.7, E-value 2.7e-10 272560025103 RES domain; Region: RES; smart00953 272560025104 Protein of unknown function (DUF2384); Region: DUF2384; pfam09722 272560025105 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560025106 1 probable transmembrane helix predicted for BPSS1822 by TMHMM2.0 at aa 193-215 272560025107 FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545 272560025108 FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254 272560025109 Pfam match to entry PF00254 FKBP, FKBP-type peptidyl-prolyl cis-trans isomerase , score 187.3, E-value 1.6e-53 272560025110 PS00453 FKBP-type peptidyl-prolyl cis-trans isomerase signature 1. 272560025111 PS00454 FKBP-type peptidyl-prolyl cis-trans isomerase signature 2. 272560025112 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560025113 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560025114 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560025115 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 32.3, E-value 7.3e-07 272560025116 Predicted helix-turn-helix motif with score 1128.000, SD 3.03 at aa 169-190, sequence LRIADLAAHCGFGMRRFHQLFC 272560025117 PS00041 Bacterial regulatory proteins, araC family signature. 272560025118 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 38.3, E-value 1.2e-08 272560025119 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560025120 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 272560025121 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 140.7, E-value 1.7e-39 272560025122 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560025123 This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801 272560025124 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 127.7, E-value 1.4e-35 272560025125 O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425 272560025126 11 probable transmembrane helices predicted for BPSS1827 by TMHMM2.0 at aa 31-53, 60-82, 97-119, 131-153, 186-208, 242-259, 269-291, 304-326, 398-420, 433-450 and 454-476 272560025127 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560025128 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560025129 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 23.9, E-value 1.4e-06 272560025130 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 272560025131 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761 272560025132 active site 272560025133 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560025134 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 76.3, E-value 4.1e-20 272560025135 PS00215 Mitochondrial energy transfer proteins signature. 272560025136 tyrosine kinase; Provisional; Region: PRK11519 272560025137 Chain length determinant protein; Region: Wzz; pfam02706 272560025138 Chain length determinant protein; Region: Wzz; cl19730 272560025139 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 272560025140 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 272560025141 2 probable transmembrane helices predicted for BPSS1830 by TMHMM2.0 at aa 34-56 and 450-469 272560025142 Pfam match to entry PF02706 wzz, Chain length determinant protein , score 136.4, E-value 3.4e-38 272560025143 Signal peptide predicted for BPSS1831 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.419 between residues 21 and 22; signal peptide 272560025144 polysaccharide export protein Wza; Provisional; Region: PRK15078 272560025145 Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563 272560025146 SLBB domain; Region: SLBB; pfam10531 272560025147 SLBB domain; Region: SLBB; pfam10531 272560025148 Pfam match to entry PF02563 Poly_export, Polysaccharide biosynthesis/export protein , score 126.7, E-value 2.9e-35 272560025149 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025150 Low molecular weight phosphatase family; Region: LMWPc; cd00115 272560025151 active site 272560025152 Pfam match to entry PF01451 LMWPc, Low molecular weight phosphotyrosine protein phosphatase , score 134.1, E-value 1.7e-37 272560025153 Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004 272560025154 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721 272560025155 Signal peptide predicted for BPSS1833 by SignalP 2.0 HMM (Signal peptide probability 0.658) with cleavage site probability 0.651 between residues 20 and 21; signal peptide 272560025156 UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984 272560025157 UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984 272560025158 Pfam match to entry PF03720 UDPG_MGDP_dh_C, UDP-glucose/GDP-mannose dehydrogenase, UDP binding domain , score 103.7, E-value 2.4e-28 272560025159 Pfam match to entry PF00984 UDPG_MGDP_dh, UDP-glucose/GDP-mannose dehydrogenase, central domain , score 165.9, E-value 4.4e-47 272560025160 Pfam match to entry PF03721 UDPG_MGDP_dh_N, UDP-glucose/GDP-mannose dehydrogenase, NAD binding domain , score 313.4, E-value 1.7e-91 272560025161 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025162 Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023 272560025163 CoA-binding domain; Region: CoA_binding_3; pfam13727 272560025164 Bacterial sugar transferase; Region: Bac_transf; pfam02397 272560025165 Pfam match to entry PF02397 Bact_transf, Bacterial sugar transferase , score 133.9, E-value 1.9e-37 272560025166 5 probable transmembrane helices predicted for BPSS1834 by TMHMM2.0 at aa 2-24, 39-61, 68-90, 100-122 and 275-297 272560025167 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560025168 GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509 272560025169 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Region: GMP_PMI; TIGR01479 272560025170 Substrate binding site; other site 272560025171 Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050 272560025172 Pfam match to entry PF00483 NTP_transferase, Nucleotidyl transferase , score 286.5, E-value 2.1e-83 272560025173 Pfam match to entry PF01050 MannoseP_isomer, Mannose-6-phosphate isomerase , score 408.1, E-value 5.6e-120 272560025174 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3293 272560025175 Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340 272560025176 Protein of unknown function (DUF3501); Region: DUF3501; pfam12007 272560025177 Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247 272560025178 Cysteine-rich domain; Region: CCG; pfam02754 272560025179 Cysteine-rich domain; Region: CCG; pfam02754 272560025180 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560025181 Rubrerythrin [Energy production and conversion]; Region: COG1592 272560025182 Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041 272560025183 binuclear metal center [ion binding]; other site 272560025184 Pfam match to entry PF02915 Rubrerythrin, Rubrerythrin , score 167.9, E-value 1.1e-47 272560025185 N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023 272560025186 Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583 272560025187 amidase catalytic site [active] 272560025188 Zn binding residues [ion binding]; other site 272560025189 substrate binding site [chemical binding]; other site 272560025190 Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471 272560025191 Pfam match to entry PF01510 Amidase_2, N-acetylmuramoyl-L-alanine amidase , score 109.6, E-value 3.8e-30 272560025192 Predicted RNA polymerase sigma factor containing a TPR repeat domain [Transcription]; Region: COG4941 272560025193 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560025194 Predicted helix-turn-helix motif with score 1031.000, SD 2.70 at aa 147-168, sequence LTTGEIARAFLTPEPTIAQRIV 272560025195 Signal peptide predicted for BPSS1842 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.962 between residues 23 and 24; signal peptide 272560025196 Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_1; cd07818 272560025197 putative hydrophobic ligand binding site [chemical binding]; other site 272560025198 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3795 272560025199 YCII-related domain; Region: YCII; cl00999 272560025200 Signal peptide predicted for BPSS1845 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.926 between residues 24 and 25; signal peptide 272560025201 YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486 272560025202 generic binding surface I; other site 272560025203 generic binding surface II; other site 272560025204 Mycoplasma pulmonis MnuA nuclease-like; Region: MnuA_DNase1-like; cd10283 272560025205 putative active site [active] 272560025206 putative catalytic site [active] 272560025207 putative Mg binding site IVb [ion binding]; other site 272560025208 putative phosphate binding site [ion binding]; other site 272560025209 putative DNA binding site [nucleotide binding]; other site 272560025210 putative Mg binding site IVa [ion binding]; other site 272560025211 Pfam match to entry PF03372 Exo_endo_phos, Endonuclease/Exonuclease/phosphatase , score 95.8, E-value 5.5e-26 272560025212 Bacterial protein of unknown function (DUF883); Region: DUF883; pfam05957 272560025213 acid shock protein precursor; Provisional; Region: PRK03577 272560025214 The SYLF domain (also called DUF500), a novel lipid-binding module; Region: SYLF; cd11524 272560025215 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025216 Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628 272560025217 7 probable transmembrane helices predicted for BPSS1848 by TMHMM2.0 at aa 22-55, 75-97, 166-188, 228-250, 260-282, 289-311 and 326-348 272560025218 Pfam match to entry PF01594 UPF0118, Domain of unknown function DUF20 , score 186.0, E-value 4e-53 272560025219 TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786 272560025220 Porin superfamily. These outer membrane channels share a beta-barrel structure that differ in strand and shear number. Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244 272560025221 Pfam match to entry PF00593 TonB_boxC, TonB dependent receptor C-terminal region , score 30.2, E-value 3.2e-06 272560025222 PS01156 TonB-dependent receptor proteins signature 2. 272560025223 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560025224 bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102 272560025225 putative substrate translocation pore; other site 272560025226 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -101.9, E-value 0.00029 272560025227 11 probable transmembrane helices predicted for BPSS1851 by TMHMM2.0 at aa 32-54, 66-88, 92-109, 122-144, 149-171, 200-222, 237-254, 267-286, 296-313, 326-348 and 358-380 272560025228 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560025229 Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130 272560025230 Prostaglandin dehydrogenases; Region: PGDH; cd05288 272560025231 NAD(P) binding site [chemical binding]; other site 272560025232 substrate binding site [chemical binding]; other site 272560025233 dimer interface [polypeptide binding]; other site 272560025234 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 140.6, E-value 1.8e-39 272560025235 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560025236 short chain dehydrogenase; Validated; Region: PRK07069 272560025237 NAD(P) binding site [chemical binding]; other site 272560025238 active site 272560025239 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 250.0, E-value 2.1e-72 272560025240 PS00061 Short-chain dehydrogenases/reductases family signature. 272560025241 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK07231 272560025242 classical (c) SDRs; Region: SDR_c; cd05233 272560025243 NAD(P) binding site [chemical binding]; other site 272560025244 active site 272560025245 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 268.8, E-value 4.6e-78 272560025246 PS00061 Short-chain dehydrogenases/reductases family signature. 272560025247 Broad specificity phosphatase PhoE and related phosphatases [General function prediction only]; Region: phoE; COG0406 272560025248 catalytic core [active] 272560025249 Pfam match to entry PF00300 PGAM, Phosphoglycerate mutase , score -81.3, E-value 8.7e-05 272560025250 Phosphotransferase enzyme family; Region: APH; pfam01636 272560025251 Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154 272560025252 putative active site [active] 272560025253 putative substrate binding site [chemical binding]; other site 272560025254 ATP binding site [chemical binding]; other site 272560025255 Pfam match to entry PF01636 APH, Phosphotransferase enzyme family , score 176.2, E-value 3.4e-50 272560025256 PS00109 Tyrosine protein kinases specific active-site signature. 272560025257 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560025258 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560025259 active site 272560025260 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 176.0, E-value 3.9e-50 272560025261 PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 272560025262 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 28.8, E-value 5.2e-09 272560025263 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560025264 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560025265 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 272560025266 substrate binding pocket [chemical binding]; other site 272560025267 dimerization interface [polypeptide binding]; other site 272560025268 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 84.3, E-value 1.7e-22 272560025269 Predicted helix-turn-helix motif with score 1703.000, SD 4.99 at aa 22-43, sequence GGISAAARALHLTQPAVTHALN 272560025270 PS00044 Bacterial regulatory proteins, lysR family signature. 272560025271 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 77.3, E-value 2.1e-20 272560025272 Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765 272560025273 Pfam match to entry PF02566 OsmC, OsmC-like protein , score 40.0, E-value 3.6e-09 272560025274 Signal peptide predicted for BPSS1860 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.588 between residues 23 and 24; signal peptide 272560025275 Domain of unknown function (DUF3472); Region: DUF3472; pfam11958 272560025276 Dyp-type peroxidase family; Region: Dyp_perox_fam; TIGR01413 272560025277 ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132 272560025278 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560025279 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560025280 Walker A/P-loop; other site 272560025281 ATP binding site [chemical binding]; other site 272560025282 Q-loop/lid; other site 272560025283 ABC transporter signature motif; other site 272560025284 Walker B; other site 272560025285 D-loop; other site 272560025286 H-loop/switch region; other site 272560025287 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 33.5, E-value 3.3e-07 272560025288 5 probable transmembrane helices predicted for BPSS1862 by TMHMM2.0 at aa 31-53, 75-97, 153-175, 180-202 and 264-286 272560025289 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 224.9, E-value 7.6e-65 272560025290 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025291 PS00211 ABC transporters family signature. 272560025292 PS00144 Asparaginase / glutaminase active site signature 1. 272560025293 Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693 272560025294 Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139 272560025295 conserved cys residue [active] 272560025296 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 113.9, E-value 2e-31 272560025297 AraC transcriptional regulators having a Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GATase1_AraC_1; cd03137 272560025298 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain [Transcription]; Region: COG4977 272560025299 conserved cys residue [active] 272560025300 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560025301 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 86.7, E-value 3.1e-23 272560025302 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 21.8, E-value 0.0011 272560025303 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 34.3, E-value 1.8e-07 272560025304 PS00589 PTS HPR component serine phosphorylation site signature. 272560025305 tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282 272560025306 catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806 272560025307 active site 272560025308 HIGH motif; other site 272560025309 dimer interface [polypeptide binding]; other site 272560025310 KMSKS motif; other site 272560025311 Pfam match to entry PF00579 tRNA-synt_1b, tRNA synthetases class I (W and Y) , score 273.6, E-value 1.7e-79 272560025312 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560025313 Signal peptide predicted for BPSS1866 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.477 between residues 37 and 38; signal peptide 272560025314 Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470 272560025315 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025316 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560025317 CAAX protease self-immunity; Region: Abi; pfam02517 272560025318 6 probable transmembrane helices predicted for BPSS1867 by TMHMM2.0 at aa 29-51, 66-88, 107-129, 149-171, 204-226 and 272-294 272560025319 Pfam match to entry PF02517 Abi, CAAX amino terminal protease , score 63.3, E-value 3.4e-16 272560025320 ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682 272560025321 putative Cl- selectivity filter; other site 272560025322 putative pore gating glutamate residue; other site 272560025323 10 probable transmembrane helices predicted for BPSS1868 by TMHMM2.0 at aa 28-50, 60-82, 102-124, 158-180, 193-212, 227-249, 269-291, 313-335, 342-364 and 384-406 272560025324 Pfam match to entry PF00654 voltage_CLC, Voltage gated chloride channel , score 31.7, E-value 3.5e-14 272560025325 2-haloalkanoic acid dehalogenase, type II; Region: HAD_type_II; TIGR01428 272560025326 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560025327 motif II; other site 272560025328 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 50.5, E-value 2.5e-12 272560025329 PS00041 Bacterial regulatory proteins, araC family signature. 272560025330 chemotaxis-specific methylesterase; Provisional; Region: PRK12555 272560025331 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560025332 active site 272560025333 phosphorylation site [posttranslational modification] 272560025334 intermolecular recognition site; other site 272560025335 CheB methylesterase; Region: CheB_methylest; pfam01339 272560025336 Pfam match to entry PF01339 CheB_methylest, CheB methylesterase , score 200.2, E-value 2.1e-57 272560025337 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 61.2, E-value 1.4e-15 272560025338 Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643 272560025339 Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088 272560025340 putative binding surface; other site 272560025341 active site 272560025342 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560025343 ATP binding site [chemical binding]; other site 272560025344 Mg2+ binding site [ion binding]; other site 272560025345 G-X-G motif; other site 272560025346 CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256 272560025347 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560025348 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560025349 active site 272560025350 phosphorylation site [posttranslational modification] 272560025351 intermolecular recognition site; other site 272560025352 dimerization interface [polypeptide binding]; other site 272560025353 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 119.0, E-value 5.9e-33 272560025354 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 77.6, E-value 1.7e-20 272560025355 Pfam match to entry PF01627 Hpt, Hpt domain , score 67.4, E-value 2e-17 272560025356 Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835 272560025357 Pfam match to entry PF01584 CheW, CheW-like domain , score 43.5, E-value 3.1e-10 272560025358 Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352 272560025359 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560025360 S-adenosylmethionine binding site [chemical binding]; other site 272560025361 Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189 272560025362 TPR motif; other site 272560025363 TPR repeat; Region: TPR_11; pfam13414 272560025364 binding surface 272560025365 Pfam match to entry PF00515 TPR, TPR Domain , score 36.7, E-value 3.3e-08 272560025366 Pfam match to entry PF01739 CheR, CheR methyltransferase, SAM binding domain , score 111.9, E-value 8.1e-31 272560025367 CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256 272560025368 Pfam match to entry PF01584 CheW, CheW-like domain , score 20.2, E-value 2.6e-05 272560025369 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560025370 Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840 272560025371 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560025372 dimerization interface [polypeptide binding]; other site 272560025373 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050 272560025374 dimer interface [polypeptide binding]; other site 272560025375 putative CheW interface [polypeptide binding]; other site 272560025376 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 87.0, E-value 2.5e-23 272560025377 Pfam match to entry PF00672 HAMP, HAMP domain , score 60.4, E-value 2.6e-15 272560025378 2 probable transmembrane helices predicted for BPSS1875 by TMHMM2.0 at aa 28-47 and 207-229 272560025379 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560025380 active site 272560025381 phosphorylation site [posttranslational modification] 272560025382 intermolecular recognition site; other site 272560025383 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560025384 dimerization interface [polypeptide binding]; other site 272560025385 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560025386 dimer interface [polypeptide binding]; other site 272560025387 phosphorylation site [posttranslational modification] 272560025388 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560025389 ATP binding site [chemical binding]; other site 272560025390 Mg2+ binding site [ion binding]; other site 272560025391 G-X-G motif; other site 272560025392 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 96.9, E-value 2.6e-26 272560025393 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 29.3, E-value 5.9e-06 272560025394 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 77.1, E-value 2.5e-20 272560025395 Signal peptide predicted for BPSS1866 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.477 between residues 34 and 35; signal peptide 272560025396 (R)-hydratase [(R)-specific enoyl-CoA hydratase]. Catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. The structure of the monomer includes a five-strand antiparallel...; Region: R_hydratase_like; cd03441 272560025397 active site 272560025398 catalytic site [active] 272560025399 Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain , score 25.9, E-value 3e-07 272560025400 Aldehyde dehydrogenase family 21A1-like; Region: ALDH_F21_RNP123; cd07147 272560025401 NAD(P) binding site [chemical binding]; other site 272560025402 catalytic residues [active] 272560025403 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score 365.1, E-value 4.8e-107 272560025404 PS00687 Aldehyde dehydrogenases glutamic acid active site. 272560025405 acetolactate synthase; Reviewed; Region: PRK08322 272560025406 Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035 272560025407 PYR/PP interface [polypeptide binding]; other site 272560025408 dimer interface [polypeptide binding]; other site 272560025409 TPP binding site [chemical binding]; other site 272560025410 Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205 272560025411 Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2...; Region: TPP_ALS; cd02010 272560025412 TPP-binding site [chemical binding]; other site 272560025413 dimer interface [polypeptide binding]; other site 272560025414 Pfam match to entry PF02775 TPP_enzymes_C, Thiamine pyrophosphate enzyme, C-terminal TPP binding domain , score 144.8, E-value 1e-40 272560025415 PS00187 Thiamine pyrophosphate enzymes signature. 272560025416 Pfam match to entry PF00205 TPP_enzymes, Thiamine pyrophosphate enzyme, central domain , score 86.7, E-value 3e-23 272560025417 Pfam match to entry PF02776 TPP_enzymes_N, Thiamine pyrophosphate enzyme, N-terminal TPP binding domain , score 183.2, E-value 2.7e-52 272560025418 NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025 272560025419 Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831 272560025420 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 269.0, E-value 3.9e-78 272560025421 12 probable transmembrane helices predicted for BPSS1880 by TMHMM2.0 at aa 15-37, 44-66, 70-89, 96-118, 123-145, 166-188, 198-220, 227-249, 279-301, 308-330, 361-383 and 390-412 272560025422 Signal peptide predicted for BPSS1881 by SignalP 2.0 HMM (Signal peptide probability 0.887) with cleavage site probability 0.836 between residues 44 and 45; signal peptide 272560025423 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399; cl19827 272560025424 Protein of unknown function (DUF445); Region: DUF445; pfam04286 272560025425 3 probable transmembrane helices predicted for BPSS1881 by TMHMM2.0 at aa 33-55, 60-80 and 419-441 272560025426 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 45.0, E-value 1.1e-10 272560025427 1 probable transmembrane helix predicted for BPSS1882 by TMHMM2.0 at aa 21-40 272560025428 Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111 272560025429 PLD-like domain; Region: PLDc_2; pfam13091 272560025430 putative active site [active] 272560025431 catalytic site [active] 272560025432 Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113 272560025433 PLD-like domain; Region: PLDc_2; pfam13091 272560025434 putative active site [active] 272560025435 catalytic site [active] 272560025436 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 25.2, E-value 9.8e-05 272560025437 Pfam match to entry PF00614 PLDc, Phospholipase D. Active site motif , score 25.5, E-value 7.8e-05 272560025438 HINT (histidine triad nucleotide-binding protein) subgroup: Members of this CD belong to the superfamily of histidine triad hydrolases that act on alpha-phosphate of ribonucleotides. This subgroup includes members from all three forms of cellular life; Region: HINT_subgroup; cd01277 272560025439 HIT family signature motif; other site 272560025440 catalytic residue [active] 272560025441 Pfam match to entry PF01230 HIT, HIT family , score 111.3, E-value 1.2e-30 272560025442 phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754 272560025443 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560025444 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560025445 Reductase C-terminal; Region: Reductase_C; pfam14759 272560025446 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 262.0, E-value 5e-76 272560025447 Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528 272560025448 [2Fe-2S] cluster binding site [ion binding]; other site 272560025449 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 89.7, E-value 4e-24 272560025450 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 272560025451 inter-subunit interface; other site 272560025452 Pfam match to entry PF00866 Ring_hydroxyl_B, Ring hydroxylating beta subunit , score 17.9, E-value 1.6e-07 272560025453 Rieske non-heme iron oxygenase (RO) family, Ortho-halobenzoate-1,2-dioxygenase (OHBDO)-like subfamily, N-terminal Rieske domain of the oxygenase alpha subunit; composed of the oxygenase alpha subunits of OHBDO, salicylate 5-hydroxylase (S5H); Region: Rieske_RO_Alpha_OHBDO_like; cd03545 272560025454 C-terminal catalytic domain of the large/alpha subunit (ahdA1c) of a ring-hydroxylating dioxygenase from Sphingomonas sp. strain P2 and related proteins; Region: RHO_alpha_C_ahdA1c-like; cd08880 272560025455 putative alpha subunit interface [polypeptide binding]; other site 272560025456 putative active site [active] 272560025457 putative substrate binding site [chemical binding]; other site 272560025458 Fe binding site [ion binding]; other site 272560025459 Pfam match to entry PF00848 Ring_hydroxyl_A, Ring hydroxylating alpha subunit (catalytic domain) , score -37.5, E-value 6.5e-07 272560025460 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 113.5, E-value 2.7e-31 272560025461 PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 272560025462 AraC-binding-like domain; Region: AraC_binding_2; pfam14525 272560025463 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560025464 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 24.8, E-value 0.00013 272560025465 Predicted helix-turn-helix motif with score 1041.000, SD 2.73 at aa 256-277, sequence LQLADIAQAAGVPERTLRDGFL 272560025466 PS00041 Bacterial regulatory proteins, araC family signature. 272560025467 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 22.1, E-value 0.00087 272560025468 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 272560025469 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560025470 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in benzoate catabolism; contains the type 2 periplasmic binding fold; Region: PBP2_BenM_CatM_CatR; cd08445 272560025471 dimerizarion interface [polypeptide binding]; other site 272560025472 CrgA pocket; other site 272560025473 substrate binding pocket [chemical binding]; other site 272560025474 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 165.7, E-value 5.1e-47 272560025475 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 117.1, E-value 2.1e-32 272560025476 PS00044 Bacterial regulatory proteins, lysR family signature. 272560025477 Predicted helix-turn-helix motif with score 1928.000, SD 5.75 at aa 16-37, sequence MNITRAAQRLHMTQPPLSRQLQ 272560025478 Muconate Lactonizing Enzyme (MLE), an homooctameric enzyme, catalyses the conversion of cis,cis-muconate (CCM) to muconolactone (ML) in the catechol branch of the beta-ketoadipate pathway. This pathway is used in soil microbes to breakdown lignin-derived...; Region: MLE; cd03318 272560025479 muconate and chloromuconate cycloisomerases; Region: mucon_cyclo; TIGR02534 272560025480 octamer interface [polypeptide binding]; other site 272560025481 active site 272560025482 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560025483 Pfam match to entry PF02746 MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain , score 161.4, E-value 1e-45 272560025484 PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 272560025485 Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain , score 314.9, E-value 6.2e-92 272560025486 PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 272560025487 catechol 1,2-dioxygenase, proteobacterial; Region: catechol_proteo; TIGR02439 272560025488 Catechol 1,2 dioxygenase (1,2-CTD) catalyzes an intradiol cleavage reaction of catechol to form cis,cis-muconate. 1,2-CTDs is homodimers with one catalytic non-heme ferric ion per monomer. They belong to the aromatic dioxygenase family, a family of...; Region: 1,2-CTD; cd03460 272560025489 dimer interface [polypeptide binding]; other site 272560025490 active site 272560025491 Pfam match to entry PF00775 Dioxygenase, Dioxygenase , score 350.0, E-value 1.6e-102 272560025492 PS00083 Intradiol ring-cleavage dioxygenases signature. 272560025493 muconolactone delta-isomerase; Region: muco_delta; TIGR03221 272560025494 Pfam match to entry PF02426 MIase, Muconolactone delta-isomerase , score 222.1, E-value 5.3e-64 272560025495 cytochrome o ubiquinol oxidase subunit IV; Region: CyoD; TIGR02847 272560025496 3 probable transmembrane helices predicted for BPSS1894 by TMHMM2.0 at aa 15-37, 44-66 and 81-103 272560025497 Pfam match to entry PF03626 COX4_pro, Prokaryotic Cytochrome C oxidase subunit IV , score 133.2, E-value 3.1e-37 272560025498 Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863 272560025499 Subunit I/III interface [polypeptide binding]; other site 272560025500 Subunit III/IV interface [polypeptide binding]; other site 272560025501 Pfam match to entry PF00510 COX3, Cytochrome c oxidase subunit III , score -146.3, E-value 8.2e-08 272560025502 5 probable transmembrane helices predicted for BPSS1895 by TMHMM2.0 at aa 21-43, 58-80, 87-109, 131-153 and 174-196 272560025503 Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843 272560025504 Ubiquinol oxidase subunit I. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane. It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662 272560025505 D-pathway; other site 272560025506 Putative ubiquinol binding site [chemical binding]; other site 272560025507 Low-spin heme (heme b) binding site [chemical binding]; other site 272560025508 Putative water exit pathway; other site 272560025509 Binuclear center (heme o3/CuB) [ion binding]; other site 272560025510 K-pathway; other site 272560025511 Putative proton exit pathway; other site 272560025512 14 probable transmembrane helices predicted for BPSS1896 by TMHMM2.0 at aa 15-37, 57-79, 104-126, 139-161, 190-212, 232-254, 279-301, 308-330, 345-367, 380-402, 417-439, 456-478, 493-515 and 593-615 272560025513 Pfam match to entry PF00115 COX1, Cytochrome C and Quinol oxidase polypeptide I , score 886.8, E-value 4.3e-264 272560025514 PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 272560025515 cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525 272560025516 The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212 272560025517 COX Aromatic Rich Motif; Region: COX_ARM; pfam06481 272560025518 Pfam match to entry PF00116 COX2, Cytochrome C oxidase subunit II, periplasmic domain , score 18.4, E-value 3.2e-05 272560025519 3 probable transmembrane helices predicted for BPSS1897 by TMHMM2.0 at aa 13-34, 49-71 and 90-112 272560025520 mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997 272560025521 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930 272560025522 active site 272560025523 FMN binding site [chemical binding]; other site 272560025524 2,4-decadienoyl-CoA binding site; other site 272560025525 catalytic residue [active] 272560025526 4Fe-4S cluster binding site [ion binding]; other site 272560025527 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560025528 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 22.4, E-value 1.3e-07 272560025529 Pfam match to entry PF00724 oxidored_FMN, NADH:flavin oxidoreductase / NADH oxidase , score 383.6, E-value 1.3e-112 272560025530 Arabinose-binding domain of AraC transcription regulator, N-term; Region: Arabinose_bd; pfam12625 272560025531 helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342 272560025532 Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165 272560025533 PS00041 Bacterial regulatory proteins, araC family signature. 272560025534 Pfam match to entry PF00165 HTH_AraC, Bacterial regulatory helix-turn-helix proteins, araC family , score 48.3, E-value 1.1e-11 272560025535 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560025536 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560025537 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560025538 dimerization interface [polypeptide binding]; other site 272560025539 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 107.2, E-value 2e-29 272560025540 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 62.2, E-value 7.4e-16 272560025541 PS00044 Bacterial regulatory proteins, lysR family signature. 272560025542 Predicted helix-turn-helix motif with score 1783.000, SD 5.26 at aa 27-48, sequence GSLSGAARALGLTQPTVGRHVA 272560025543 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560025544 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560025545 NAD(P) binding site [chemical binding]; other site 272560025546 active site 272560025547 DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906 272560025548 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560025549 The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in benzoate catabolism; contains the type 2 periplasmic binding fold; Region: PBP2_BenM_CatM_CatR; cd08445 272560025550 dimerizarion interface [polypeptide binding]; other site 272560025551 CrgA pocket; other site 272560025552 substrate binding pocket [chemical binding]; other site 272560025553 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 162.1, E-value 6.3e-46 272560025554 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 119.9, E-value 3.2e-33 272560025555 PS00044 Bacterial regulatory proteins, lysR family signature. 272560025556 Predicted helix-turn-helix motif with score 1483.000, SD 4.24 at aa 16-37, sequence QNFTRAAERLHIAQPPLSRQIQ 272560025557 benzoate 1,2-dioxygenase, large subunit; Region: benzo_1_2_benA; TIGR03229 272560025558 Rieske non-heme iron oxygenase (RO) family, 2-Halobenzoate 1,2-dioxygenase (HBDO) subfamily, N-terminal Rieske domain of the oxygenase alpha subunit; ROs comprise a large class of aromatic ring-hydroxylating dioxygenases that enable microorganisms to...; Region: Rieske_RO_Alpha_HBDO; cd03542 272560025559 C-terminal catalytic domain of the oxygenase alpha subunit of Pseudomonas resinovorans strain CA10 anthranilate 1,2-dioxygenase and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_AntDO-like; cd08879 272560025560 putative alpha subunit interface [polypeptide binding]; other site 272560025561 putative active site [active] 272560025562 putative substrate binding site [chemical binding]; other site 272560025563 Fe binding site [ion binding]; other site 272560025564 Pfam match to entry PF00355 Rieske, Rieske [2Fe-2S] domain , score 115.1, E-value 8.9e-32 272560025565 PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 272560025566 Pfam match to entry PF00848 Ring_hydroxyl_A, Ring hydroxylating alpha subunit (catalytic domain) , score 92.8, E-value 4.3e-25 272560025567 Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667 272560025568 inter-subunit interface; other site 272560025569 Pfam match to entry PF00866 Ring_hydroxyl_B, Ring hydroxylating beta subunit , score 197.6, E-value 1.3e-56 272560025570 anthranilate dioxygenase reductase; Provisional; Region: antC; PRK11872 272560025571 2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207 272560025572 catalytic loop [active] 272560025573 iron binding site [ion binding]; other site 272560025574 Benzoate dioxygenase reductase (BenDO) FAD/NAD binding domain. Oxygenases oxidize hydrocarbons using dioxygen as the oxidant. As a Class I bacterial dioxygenases, benzoate dioxygenase like proteins combine an [2Fe-2S] cluster containing N-terminal...; Region: BenDO_FAD_NAD; cd06209 272560025575 FAD binding pocket [chemical binding]; other site 272560025576 FAD binding motif [chemical binding]; other site 272560025577 phosphate binding motif [ion binding]; other site 272560025578 beta-alpha-beta structure motif; other site 272560025579 NAD binding pocket [chemical binding]; other site 272560025580 Pfam match to entry PF00111 fer2, 2Fe-2S iron-sulfur cluster binding domain , score 81.2, E-value 1.4e-21 272560025581 PS00197 2Fe-2S ferredoxins, iron-sulfur binding region signature. 272560025582 Pfam match to entry PF00970 FAD_binding_6, Oxidoreductase FAD-binding domain , score 113.1, E-value 3.5e-31 272560025583 Pfam match to entry PF00175 NAD_binding_1, Oxidoreductase NAD-binding domain , score 107.4, E-value 1.8e-29 272560025584 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Provisional; Region: benD; PRK12823 272560025585 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase (DHB DH)-like, classical (c) SDR; Region: DHB_DH-like_SDR_c; cd08937 272560025586 putative NAD(P) binding site [chemical binding]; other site 272560025587 active site 272560025588 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 256.6, E-value 2.1e-74 272560025589 PS00061 Short-chain dehydrogenases/reductases family signature. 272560025590 Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These...; Region: Esterase_lipase; cl19094 272560025591 Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144 272560025592 alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859 272560025593 substrate binding pocket [chemical binding]; other site 272560025594 Pfam match to entry PF00135 COesterase, Carboxylesterase , score 10.5, E-value 0.0018 272560025595 1 probable transmembrane helix predicted for BPSS1907 by TMHMM2.0 at aa 41-60 272560025596 Transcriptional regulators [Transcription]; Region: MarR; COG1846 272560025597 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220 272560025598 Pfam match to entry PF01047 MarR, MarR family , score 48.7, E-value 8.6e-12 272560025599 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 272560025600 catalytic triad [active] 272560025601 conserved cis-peptide bond; other site 272560025602 Pfam match to entry PF00857 Isochorismatase, Isochorismatase , score 28.8, E-value 2.8e-07 272560025603 Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515 272560025604 7 probable transmembrane helices predicted for BPSS1910 by TMHMM2.0 at aa 44-63, 73-95, 115-134, 144-166, 187-209, 259-281 and 313-335 272560025605 Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260 272560025606 BNR repeat-like domain; Region: BNR_2; pfam13088 272560025607 Asp-box motif; other site 272560025608 1 probable transmembrane helix predicted for BPSS1911 by TMHMM2.0 at aa 21-43 272560025609 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 10.9, E-value 1.4 272560025610 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 17.9, E-value 0.016 272560025611 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 12.4, E-value 0.73 272560025612 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 16.3, E-value 0.048 272560025613 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 13.4, E-value 0.35 272560025614 Pfam match to entry PF02012 BNR, BNR/Asp-box repeat , score 5.8, E-value 6.8 272560025615 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560025616 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560025617 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560025618 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560025619 Pfam match to entry PF01610 Transposase_12, Transposase , score 371.4, E-value 6.3e-109 272560025620 Signal peptide predicted for BPSS1913 by SignalP 2.0 HMM (Signal peptide probability 0.767) with cleavage site probability 0.653 between residues 52 and 53; signal peptide 272560025621 lysine transporter; Provisional; Region: PRK10836 272560025622 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560025623 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 773.7, E-value 4.7e-230 272560025624 12 probable transmembrane helices predicted for BPSS1913 by TMHMM2.0 at aa 27-49, 59-81, 109-131, 136-158, 165-187, 202-224, 251-273, 296-318, 353-372, 376-398, 419-441 and 451-473 272560025625 PS00218 Amino acid permeases signature. 272560025626 Predicted metal-dependent hydrolase; Region: Metal_hydrol; pfam10118 272560025627 1 probable transmembrane helix predicted for BPSS1914 by TMHMM2.0 at aa 178-200 272560025628 Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236 272560025629 Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849 272560025630 Beta-Casp domain; Region: Beta-Casp; smart01027 272560025631 RNA-metabolizing metallo-beta-lactamase; Region: RMMBL; pfam07521 272560025632 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 15.9, E-value 0.00011 272560025633 acetoacetyl-CoA reductase; Region: AcAcCoA_reduct; TIGR01829 272560025634 beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333 272560025635 NAD(P) binding site [chemical binding]; other site 272560025636 homotetramer interface [polypeptide binding]; other site 272560025637 homodimer interface [polypeptide binding]; other site 272560025638 active site 272560025639 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 283.9, E-value 1.3e-82 272560025640 PS00061 Short-chain dehydrogenases/reductases family signature. 272560025641 fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161 272560025642 effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038 272560025643 ligand binding site [chemical binding]; other site 272560025644 flexible hinge region; other site 272560025645 helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092 272560025646 putative switch regulator; other site 272560025647 non-specific DNA interactions [nucleotide binding]; other site 272560025648 DNA binding site [nucleotide binding] 272560025649 sequence specific DNA binding site [nucleotide binding]; other site 272560025650 putative cAMP binding site [chemical binding]; other site 272560025651 Pfam match to entry PF00027 cNMP_binding, Cyclic nucleotide-binding domain , score 51.6, E-value 1.2e-12 272560025652 Pfam match to entry PF00325 crp, Bacterial regulatory proteins, crp family , score 46.7, E-value 3.3e-11 272560025653 Predicted helix-turn-helix motif with score 1732.000, SD 5.09 at aa 213-234, sequence MTREEIGCYLGMKLETVSRMLS 272560025654 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 272560025655 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298 272560025656 putative NAD(P) binding site [chemical binding]; other site 272560025657 putative substrate binding site [chemical binding]; other site 272560025658 catalytic Zn binding site [ion binding]; other site 272560025659 structural Zn binding site [ion binding]; other site 272560025660 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 222.0, E-value 5.7e-64 272560025661 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560025662 Protein of unknown function (DUF3562); Region: DUF3562; pfam12085 272560025663 Protein of unknown function (DUF3564); Region: DUF3564; pfam12087 272560025664 Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611 272560025665 PS00430 TonB-dependent receptor proteins signature 1. 272560025666 Pfam match to entry PF03641 Lysine_decarbox, Lysine decarboxylase , score 176.3, E-value 3.4e-50 272560025667 Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823 272560025668 BON domain; Region: BON; pfam04972 272560025669 BON domain; Region: BON; pfam04972 272560025670 Sulfotransferase domain; Region: Sulfotransfer_1; cl19239 272560025671 Pfam match to entry PF00685 Sulfotransfer, Sulfotransferase , score -89.6, E-value 0.031 272560025672 Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027 272560025673 ligand-binding site [chemical binding]; other site 272560025674 Pfam match to entry PF01583 APS_kinase, Adenylylsulfate kinase , score 316.8, E-value 1.7e-92 272560025675 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025676 ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144 272560025677 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560025678 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560025679 dimer interface [polypeptide binding]; other site 272560025680 putative CheW interface [polypeptide binding]; other site 272560025681 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 315.9, E-value 3.2e-92 272560025682 PS00538 Bacterial chemotaxis sensory transducers signature. 272560025683 Pfam match to entry PF00672 HAMP, HAMP domain , score 27.3, E-value 2.3e-05 272560025684 2 probable transmembrane helices predicted for BPSS1927 by TMHMM2.0 at aa 10-32 and 196-215 272560025685 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 272560025686 putative active site [active] 272560025687 putative metal binding site [ion binding]; other site 272560025688 Signal peptide predicted for BPSS1929 by SignalP 2.0 HMM (Signal peptide probability 0.841) with cleavage site probability 0.417 between residues 34 and 35; signal peptide 272560025689 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family; Region: outer_NodT; TIGR01845 272560025690 Outer membrane efflux protein; Region: OEP; pfam02321 272560025691 Outer membrane efflux protein; Region: OEP; pfam02321 272560025692 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 128.3, E-value 9.3e-36 272560025693 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 63.6, E-value 2.8e-16 272560025694 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025695 Signal peptide predicted for BPSS1930 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.448 between residues 19 and 20; signal peptide 272560025696 ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971 272560025697 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560025698 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 32.5, E-value 6.5e-07 272560025699 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 272560025700 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 272560025701 Walker A/P-loop; other site 272560025702 ATP binding site [chemical binding]; other site 272560025703 Q-loop/lid; other site 272560025704 ABC transporter signature motif; other site 272560025705 Walker B; other site 272560025706 D-loop; other site 272560025707 H-loop/switch region; other site 272560025708 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 204.1, E-value 1.4e-58 272560025709 PS00211 ABC transporters family signature. 272560025710 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025711 ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591 272560025712 MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704 272560025713 FtsX-like permease family; Region: FtsX; pfam02687 272560025714 Pfam match to entry PF02687 DUF214, Predicted permease , score 56.3, E-value 4.2e-14 272560025715 4 probable transmembrane helices predicted for BPSS1932 by TMHMM2.0 at aa 21-43, 257-279, 299-321 and 336-358 272560025716 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560025717 NLPA lipoprotein; Region: Lipoprotein_9; cl19159 272560025718 2 probable transmembrane helices predicted for BPSS1933 by TMHMM2.0 at aa 9-31 and 36-58 272560025719 Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293 272560025720 Ligand Binding Site [chemical binding]; other site 272560025721 Pfam match to entry PF00582 Usp, Universal stress protein family , score 71.7, E-value 1e-18 272560025722 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560025723 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 73.4, E-value 3e-19 272560025724 Predicted helix-turn-helix motif with score 1061.000, SD 2.80 at aa 51-72, sequence ARIDDIAARAGMSKGGVYTHFG 272560025725 copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837 272560025726 Outer membrane efflux protein; Region: OEP; pfam02321 272560025727 Outer membrane efflux protein; Region: OEP; pfam02321 272560025728 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 117.8, E-value 1.3e-32 272560025729 Pfam match to entry PF02321 OEP, Outer membrane efflux protein , score 178.2, E-value 8.8e-51 272560025730 Signal peptide predicted for BPSS1937 by SignalP 2.0 HMM (Signal peptide probability 0.835) with cleavage site probability 0.354 between residues 21 and 22; signal peptide 272560025731 HlyD family secretion protein; Region: HlyD; pfam00529 272560025732 Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533 272560025733 Proteobacterial lipase chaperone protein; Region: Lipase_chap; pfam03280 272560025734 HlyD family secretion protein; Region: HlyD_3; pfam13437 272560025735 Pfam match to entry PF00529 HlyD, HlyD family secretion protein , score 88.2, E-value 1.1e-23 272560025736 ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123 272560025737 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 272560025738 Walker A/P-loop; other site 272560025739 ATP binding site [chemical binding]; other site 272560025740 Q-loop/lid; other site 272560025741 ABC transporter signature motif; other site 272560025742 Walker B; other site 272560025743 D-loop; other site 272560025744 H-loop/switch region; other site 272560025745 ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230 272560025746 Walker A/P-loop; other site 272560025747 ATP binding site [chemical binding]; other site 272560025748 Q-loop/lid; other site 272560025749 ABC transporter signature motif; other site 272560025750 Walker B; other site 272560025751 D-loop; other site 272560025752 H-loop/switch region; other site 272560025753 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560025754 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 272560025755 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 180.1, E-value 2.4e-51 272560025756 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025757 PS00079 Multicopper oxidases signature 1. 272560025758 PS00211 ABC transporters family signature. 272560025759 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 205.3, E-value 6.1e-59 272560025760 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025761 High content in Ala residues. Also high GC content (79.74%) 272560025762 5 probable transmembrane helices predicted for BPSS1938 by TMHMM2.0 at aa 880-902, 929-948, 958-980, 987-1009 and 1047-1069 272560025763 YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; cl19580 272560025764 ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842 272560025765 ABC-2 type transporter; Region: ABC2_membrane; pfam01061 272560025766 4 probable transmembrane helices predicted for BPSS1939 by TMHMM2.0 at aa 226-248, 258-280, 287-306 and 344-363 272560025767 PS00890 ABC-2 type transport system integral membrane proteins signature. 272560025768 PAS fold; Region: PAS_4; pfam08448 272560025769 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560025770 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560025771 dimer interface [polypeptide binding]; other site 272560025772 phosphorylation site [posttranslational modification] 272560025773 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560025774 ATP binding site [chemical binding]; other site 272560025775 Mg2+ binding site [ion binding]; other site 272560025776 G-X-G motif; other site 272560025777 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560025778 active site 272560025779 phosphorylation site [posttranslational modification] 272560025780 intermolecular recognition site; other site 272560025781 dimerization interface [polypeptide binding]; other site 272560025782 Pfam match to entry PF00785 PAC, PAC motif , score 18.7, E-value 0.0091 272560025783 PS00584 pfkB family of carbohydrate kinases signature 2. 272560025784 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 20.1, E-value 0.0003 272560025785 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 108.3, E-value 9.9e-30 272560025786 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 59.2, E-value 5.6e-15 272560025787 Cache domain; Region: Cache_2; pfam08269 272560025788 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283 272560025789 Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386 272560025790 dimer interface [polypeptide binding]; other site 272560025791 putative CheW interface [polypeptide binding]; other site 272560025792 Pfam match to entry PF00015 MCPsignal, Methyl-accepting chemotaxis protein (MCP) signaling domain , score 254.5, E-value 9.5e-74 272560025793 2 probable transmembrane helices predicted for BPSS1941 by TMHMM2.0 at aa 10-32 and 188-210 272560025794 2 probable transmembrane helices predicted for BPSS1942 by TMHMM2.0 at aa 58-80 and 90-112 272560025795 Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064 272560025796 Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297 272560025797 NAD binding site [chemical binding]; other site 272560025798 substrate binding site [chemical binding]; other site 272560025799 catalytic Zn binding site [ion binding]; other site 272560025800 tetramer interface [polypeptide binding]; other site 272560025801 structural Zn binding site [ion binding]; other site 272560025802 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 392.1, E-value 3.6e-115 272560025803 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560025804 ATP synthase; Region: ATP-synt; pfam00231 272560025805 core domain interface [polypeptide binding]; other site 272560025806 delta subunit interface [polypeptide binding]; other site 272560025807 epsilon subunit interface [polypeptide binding]; other site 272560025808 Pfam match to entry PF00231 ATP-synt, ATP synthase , score -121.0, E-value 1.5e-05 272560025809 F0F1 ATP synthase subunit alpha; Provisional; Region: PRK13343 272560025810 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560025811 RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233 272560025812 Walker A motif; other site 272560025813 ATP binding site [chemical binding]; other site 272560025814 Walker B motif; other site 272560025815 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 272560025816 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain , score 21.2, E-value 5e-06 272560025817 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 439.2, E-value 2.4e-129 272560025818 PS00152 ATP synthase alpha and beta subunits signature. 272560025819 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025820 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 31.5, E-value 1.3e-06 272560025821 alternate F1F0 ATPase, F0 subunit B; Region: alt_F1F0_F0_B; TIGR03321 272560025822 Pfam match to entry PF00430 ATP-synt_B, ATP synthase B/B' CF(0) , score 7.2, E-value 0.00011 272560025823 1 probable transmembrane helix predicted for BPSS1947 by TMHMM2.0 at aa 5-27 272560025824 F0F1 ATP synthase subunit C; Provisional; Region: PRK13468 272560025825 Signal peptide predicted for BPSS1948 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.996 between residues 27 and 28; signal peptide 272560025826 Pfam match to entry PF00137 ATP-synt_C, ATP synthase subunit C , score 62.9, E-value 4.4e-16 272560025827 2 probable transmembrane helices predicted for BPSS1948 by TMHMM2.0 at aa 5-27 and 54-76 272560025828 PS00605 ATP synthase c subunit signature. 272560025829 F0F1 ATP synthase subunit A; Provisional; Region: PRK13421 272560025830 Signal peptide predicted for BPSS1949 by SignalP 2.0 HMM (Signal peptide probability 0.871) with cleavage site probability 0.782 between residues 25 and 26; signal peptide 272560025831 5 probable transmembrane helices predicted for BPSS1949 by TMHMM2.0 at aa 15-37, 78-100, 110-127, 165-187 and 197-219 272560025832 Pfam match to entry PF00119 ATP-synt_A, ATP synthase A chain , score 98.8, E-value 6.8e-27 272560025833 F1/F0 ATPase, Methanosarcina type, subunit 2; Region: F1F0_chp_2; TIGR03165 272560025834 3 probable transmembrane helices predicted for BPSS1950 by TMHMM2.0 at aa 10-32, 39-61 and 66-88 272560025835 Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527 272560025836 2 probable transmembrane helices predicted for BPSS1951 by TMHMM2.0 at aa 99-118 and 123-145 272560025837 F0F1 ATP synthase subunit epsilon; Provisional; Region: PRK13447 272560025838 mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152 272560025839 gamma subunit interface [polypeptide binding]; other site 272560025840 epsilon subunit interface [polypeptide binding]; other site 272560025841 LBP interface [polypeptide binding]; other site 272560025842 Pfam match to entry PF02823 ATP-synt_DE_N, ATP synthase, Delta/Epsilon chain, beta-sandwich domain , score 12.2, E-value 7e-05 272560025843 F0F1 ATP synthase subunit beta; Provisional; Region: PRK12597 272560025844 ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874 272560025845 F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133 272560025846 alpha subunit interaction interface [polypeptide binding]; other site 272560025847 Walker A motif; other site 272560025848 ATP binding site [chemical binding]; other site 272560025849 Walker B motif; other site 272560025850 inhibitor binding site; inhibition site 272560025851 ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306 272560025852 Pfam match to entry PF00306 ATP-synt_ab_C, ATP synthase alpha/beta chain, C terminal domain , score 102.9, E-value 4e-28 272560025853 Pfam match to entry PF00006 ATP-synt_ab, ATP synthase alpha/beta family, nucleotide-binding domain , score 367.7, E-value 8e-108 272560025854 PS00152 ATP synthase alpha and beta subunits signature. 272560025855 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025856 Pfam match to entry PF02874 ATP-synt_ab_N, ATP synthase alpha/beta family, beta-barrel domain , score 61.9, E-value 9.1e-16 272560025857 Poly-beta-hydroxybutyrate polymerase N terminal; Region: PHBC_N; pfam12551 272560025858 poly(R)-hydroxyalkanoic acid synthase, class I; Region: PHA_synth_I; TIGR01838 272560025859 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus; Region: PhaC_N; pfam07167 272560025860 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 33.1, E-value 4.1e-07 272560025861 PS00213 Lipocalin signature. 272560025862 bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated; Region: PRK08190 272560025863 (R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449 272560025864 dimer interaction site [polypeptide binding]; other site 272560025865 substrate-binding tunnel; other site 272560025866 active site 272560025867 catalytic site [active] 272560025868 substrate binding site [chemical binding]; other site 272560025869 Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212 272560025870 Pfam match to entry PF01575 MaoC_dehydratas, MaoC like domain , score 94.5, E-value 1.4e-25 272560025871 Pfam match to entry PF01515 PTA_PTB, Phosphate acetyl/butaryl transferase , score 103.7, E-value 2.3e-28 272560025872 acetate kinase; Provisional; Region: PRK07058 272560025873 Pfam match to entry PF00871 Acetate_kinase, Acetokinase , score 314.0, E-value 1.1e-91 272560025874 PS01076 Acetate and butyrate kinases family signature 2. 272560025875 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164 272560025876 putative substrate binding site [chemical binding]; other site 272560025877 putative ATP binding site [chemical binding]; other site 272560025878 Pfam match to entry PF00294 pfkB, pfkB family carbohydrate kinase , score 150.5, E-value 1.8e-42 272560025879 PS00583 pfkB family of carbohydrate kinases signature 1. 272560025880 Predicted periplasmic or secreted lipoprotein [General function prediction only]; Region: OsmY; COG2823 272560025881 BON domain; Region: BON; pfam04972 272560025882 BON domain; Region: BON; pfam04972 272560025883 Cytidine deaminase [Nucleotide transport and metabolism]; Region: Cdd; COG0295 272560025884 Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283 272560025885 active site 272560025886 catalytic motif [active] 272560025887 Zn binding site [ion binding]; other site 272560025888 Pfam match to entry PF00383 dCMP_cyt_deam, Cytidine and deoxycytidylate deaminase zinc-binding region , score 97.9, E-value 1.3e-26 272560025889 PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 272560025890 thymidine phosphorylase; Region: T_phosphoryl; TIGR02643 272560025891 Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885 272560025892 Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591 272560025893 Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941 272560025894 Pfam match to entry PF00591 Glycos_transf_3, Glycosyl transferase, a/b domain , score 175.2, E-value 6.8e-50 272560025895 PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 272560025896 Pfam match to entry PF02885 Glycos_trans_3N, Glycosyl transferase, helical bundle domain , score 20.8, E-value 0.00055 272560025897 2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959 272560025898 intersubunit interface [polypeptide binding]; other site 272560025899 active site 272560025900 catalytic residue [active] 272560025901 Pfam match to entry PF01791 DeoC, Deoxyribose-phosphate aldolase , score 203.1, E-value 2.7e-58 272560025902 Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972 272560025903 Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773 272560025904 Nucleoside recognition; Region: Gate; pfam07670 272560025905 Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662 272560025906 Pfam match to entry PF01773 Nucleoside_tra2, Na+ dependent nucleoside transporter , score 626.2, E-value 1.2e-185 272560025907 10 probable transmembrane helices predicted for BPSS1963 by TMHMM2.0 at aa 4-22, 29-51, 96-118, 131-153, 173-195, 202-224, 258-280, 287-309, 363-385 and 398-420 272560025908 Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381 272560025909 Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243 272560025910 GST_N family, unknown subfamily 4; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_4; cd03056 272560025911 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560025912 putative C-terminal domain interface [polypeptide binding]; other site 272560025913 putative GSH binding site (G-site) [chemical binding]; other site 272560025914 putative dimer interface [polypeptide binding]; other site 272560025915 C-terminal, alpha helical domain of an unknown subfamily 7 of Glutathione S-transferases; Region: GST_C_7; cd03206 272560025916 putative N-terminal domain interface [polypeptide binding]; other site 272560025917 putative dimer interface [polypeptide binding]; other site 272560025918 putative substrate binding pocket (H-site) [chemical binding]; other site 272560025919 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 54.7, E-value 1.3e-13 272560025920 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 78.8, E-value 7.2e-21 272560025921 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560025922 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560025923 The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422 272560025924 putative effector binding pocket; other site 272560025925 dimerization interface [polypeptide binding]; other site 272560025926 1 probable transmembrane helix predicted for BPSS1966 by TMHMM2.0 at aa 13-35 272560025927 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 81.3, E-value 1.2e-21 272560025928 Predicted helix-turn-helix motif with score 1377.000, SD 3.88 at aa 28-49, sequence GSLTAAAERLGLAKTMVSAHVQ 272560025929 PS00044 Bacterial regulatory proteins, lysR family signature. 272560025930 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 175.5, E-value 5.8e-50 272560025931 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560025932 Bacterial regulatory proteins, tetR family; Region: TetR_N; cl19382 272560025933 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 25.1, E-value 8.8e-05 272560025934 short chain dehydrogenase; Provisional; Region: PRK06181 272560025935 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560025936 NAD(P) binding site [chemical binding]; other site 272560025937 active site 272560025938 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 194.4, E-value 1.1e-55 272560025939 PS00061 Short-chain dehydrogenases/reductases family signature. 272560025940 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 272560025941 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738 272560025942 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560025943 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560025944 1 probable transmembrane helix predicted for BPSS1970 by TMHMM2.0 at aa 5-27 272560025945 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 75.3, E-value 8e-20 272560025946 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560025947 metal binding site [ion binding]; metal-binding site 272560025948 active site 272560025949 I-site; other site 272560025950 2 probable transmembrane helices predicted for BPSS1971 by TMHMM2.0 at aa 41-63 and 325-344 272560025951 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 218.3, E-value 7.5e-63 272560025952 Protein of unknown function (DUF3268); Region: DUF3268; pfam11672 272560025953 Signal peptide predicted for BPSS1973 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.990 between residues 35 and 36; signal peptide 272560025954 Activation domain of S53 peptidases; Region: Pro-peptidase_S53; cd11377 272560025955 peptidase domain interface [polypeptide binding]; other site 272560025956 Peptidase domain in the S53 family; Region: Peptidases_S53; cd04056 272560025957 active site 272560025958 catalytic triad [active] 272560025959 calcium binding site [ion binding]; other site 272560025960 PS00138 Serine proteases, subtilase, serine active site. 272560025961 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560025962 Signal peptide predicted for BPSS1974 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.442 between residues 32 and 33; signal peptide 272560025963 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560025964 Pfam match to entry PF01391 Collagen, Collagen triple helix repeat (20 copies) , score 22.1, E-value 1.4e-05 272560025965 Pfam match to entry PF01391 Collagen, Collagen triple helix repeat (20 copies) , score 23.8, E-value 1.2e-05 272560025966 Phospholipid methyltransferase; Region: PEMT; cl17370 272560025967 8 probable transmembrane helices predicted for BPSS1975 by TMHMM2.0 at aa 21-40, 50-72, 93-115, 125-147, 204-226, 259-281, 301-323 and 364-386 272560025968 10 probable transmembrane helices predicted for BPSS1976 by TMHMM2.0 at aa 40-62, 66-88, 109-131, 146-168, 202-221, 241-263, 270-292, 327-349, 362-384 and 399-421 272560025969 PS00241 Growth factor and cytokines receptors family signature 1. 272560025970 Signal peptide predicted for BPSS1977 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.708 between residues 29 and 30; signal peptide 272560025971 Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150 272560025972 cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841 272560025973 Chain length determinant protein; Region: Wzz; pfam02706 272560025974 G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807 272560025975 The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203 272560025976 Pfam match to entry PF02706 wzz, Chain length determinant protein , score 14.5, E-value 2.2e-05 272560025977 2 probable transmembrane helices predicted for BPSS1978 by TMHMM2.0 at aa 33-52 and 458-480 272560025978 PS00017 ATP/GTP-binding site motif A (P-loop). 272560025979 PS00107 Protein kinases ATP-binding region signature. 272560025980 Glycosyl hydrolase catalytic core; Region: Glyco_hydro_cc; pfam11790 272560025981 1 probable transmembrane helix predicted for BPSS1980 by TMHMM2.0 at aa 55-77 272560025982 Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153 272560025983 putative metal binding site [ion binding]; other site 272560025984 putative homodimer interface [polypeptide binding]; other site 272560025985 putative homotetramer interface [polypeptide binding]; other site 272560025986 putative homodimer-homodimer interface [polypeptide binding]; other site 272560025987 putative allosteric switch controlling residues; other site 272560025988 Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230 272560025989 Pfam match to entry PF01545 Cation_efflux, Cation efflux family , score 194.4, E-value 1.2e-55 272560025990 6 probable transmembrane helices predicted for BPSS1982 by TMHMM2.0 at aa 32-54, 59-78, 98-120, 133-152, 289-311 and 316-338 272560025991 Catalytic domain, repeat 1, of Deoxyribonuclease II and similar proteins; Region: PLDc_DNaseII_1; cd09120 272560025992 Deoxyribonuclease II; Region: DNase_II; pfam03265 272560025993 putative active site [active] 272560025994 catalytic site [active] 272560025995 Catalytic domain, repeat 2, of Deoxyribonuclease II and similar proteins; Region: PLDc_DNaseII_2; cd09121 272560025996 putative active site [active] 272560025997 catalytic site [active] 272560025998 Pfam match to entry PF03265 DNase_II, Deoxyribonuclease II , score 168.6, E-value 7e-48 272560025999 Phosphorylase superfamily; Region: PNP_UDP_1; cl00303 272560026000 Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149 272560026001 active site 272560026002 metal binding site [ion binding]; metal-binding site 272560026003 Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409 272560026004 Pfam match to entry PF00149 Metallophos, Calcineurin-like phosphoesterase , score 58.6, E-value 8.6e-15 272560026005 Ferritin-like; Region: Ferritin-like; pfam12902 272560026006 aldolase II superfamily protein; Provisional; Region: PRK07044 272560026007 intersubunit interface [polypeptide binding]; other site 272560026008 active site 272560026009 Zn2+ binding site [ion binding]; other site 272560026010 Pfam match to entry PF00596 Aldolase_II, Class II Aldolase and Adducin N-terminal domain , score 217.2, E-value 1.6e-62 272560026011 Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_1; cd10033 272560026012 putative uracil binding site [chemical binding]; other site 272560026013 putative active site [active] 272560026014 Pfam match to entry PF03167 UDG, Uracil DNA glycosylase superfamily , score 31.1, E-value 1.2e-06 272560026015 Signal peptide predicted for BPSS1992 by SignalP 2.0 HMM (Signal peptide probability 0.949) with cleavage site probability 0.896 between residues 26 and 27; signal peptide 272560026016 X-Pro dipeptidyl-peptidase (S15 family); Region: Peptidase_S15; pfam02129 272560026017 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; pfam08530 272560026018 Pfam match to entry PF02129 Peptidase_S15, X-Pro dipeptidyl-peptidase (S15 family) , score 134.5, E-value 2.4e-44 272560026019 Signal peptide predicted for BPSS1993 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.889 between residues 30 and 31; signal peptide 272560026020 Peptidase S8 family domain, uncharacterized subfamily 13; Region: Peptidases_S8_13; cd07496 272560026021 Subtilase family; Region: Peptidase_S8; pfam00082 272560026022 active site 272560026023 catalytic triad [active] 272560026024 Pfam match to entry PF00082 Peptidase_S8, Subtilase , score 249.1, E-value 4e-72 272560026025 PS00138 Serine proteases, subtilase, serine active site. 272560026026 PS00137 Serine proteases, subtilase, histidine active site. 272560026027 heavy metal response regulator; Region: cztR_silR_copR; TIGR01387 272560026028 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560026029 active site 272560026030 phosphorylation site [posttranslational modification] 272560026031 intermolecular recognition site; other site 272560026032 dimerization interface [polypeptide binding]; other site 272560026033 Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383 272560026034 DNA binding site [nucleotide binding] 272560026035 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 136.2, E-value 4e-38 272560026036 Pfam match to entry PF00486 trans_reg_C, Transcriptional regulatory protein, C terminal , score 89.3, E-value 5.1e-24 272560026037 Signal peptide predicted for BPSS1995 by SignalP 2.0 HMM (Signal peptide probability 0.883) with cleavage site probability 0.372 between residues 38 and 39 272560026038 heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386 272560026039 Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225 272560026040 dimerization interface [polypeptide binding]; other site 272560026041 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560026042 dimer interface [polypeptide binding]; other site 272560026043 phosphorylation site [posttranslational modification] 272560026044 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560026045 ATP binding site [chemical binding]; other site 272560026046 Mg2+ binding site [ion binding]; other site 272560026047 G-X-G motif; other site 272560026048 1 probable transmembrane helix predicted for BPSS1995 by TMHMM2.0 at aa 170-192 272560026049 Pfam match to entry PF00672 HAMP, HAMP domain , score 56.0, E-value 5.3e-14 272560026050 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 61.0, E-value 1.6e-15 272560026051 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 150.3, E-value 2.3e-42 272560026052 Signal peptide predicted for BPSS1996 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 1.000 between residues 38 and 39; signal peptide 272560026053 Domain of unknown function (DUF4148); Region: DUF4148; pfam13663 272560026054 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026055 Signal peptide predicted for BPSS1997 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.969 between residues 23 and 24; signal peptide 272560026056 Beta-lactamase class D [Defense mechanisms]; Region: COG2602 272560026057 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026058 PS00337 Beta-lactamase class-D active site. 272560026059 Signal peptide predicted for BPSS1998 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.430 between residues 22 and 23; signal peptide 272560026060 Uncharacterized conserved protein [Function unknown]; Region: COG3391 272560026061 40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276 272560026062 40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276 272560026063 Phosphoesterase family; Region: Phosphoesterase; pfam04185 272560026064 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560026065 Iron permease FTR1 family; Region: FTR1; cl00475 272560026066 Pfam match to entry PF03239 FTR1, Iron permease FTR1 family , score 69.8, E-value 3.9e-18 272560026067 6 probable transmembrane helices predicted for BPSS1999 by TMHMM2.0 at aa 7-29, 39-61, 68-87, 150-172, 185-207 and 238-260 272560026068 Signal peptide predicted for BPSS2000 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.994 between residues 25 and 26; signal peptide 272560026069 Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473 272560026070 Similar to Salmonella typhimurium glutamate/aspartate periplasmic binding protein precursor gltI SWALL:GLTI_SALTY (SWALL:Q9ZF60) (302 aa) fasta scores: E(): 2.4e-30, 42.92% id in 212 aa, and to Chromobacterium violaceum ATCC 12472 probable amino acid ABC transporter periplasmic amino acid-binding protein SWALL:Q7P1U2 (EMBL:AE016910) (302 aa) fasta scores: E(): 2.5e-32, 45.54% id in 213 aa. CDS contains a frameshift after codon 10. Alternatively, the CDS may be contain a nonsense mutation before codon 11; periplasmic binding protein precursor (pseudogene) 272560026071 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 58.6, E-value 8.7e-15 272560026072 Signal peptide predicted for BPSS2002 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.987 between residues 21 and 22 272560026073 Signal peptide predicted for BPSS2003 by SignalP 2.0 HMM (Signal peptide probability 0.867) with cleavage site probability 0.841 between residues 30 and 31; signal peptide 272560026074 Predicted metal-binding protein [General function prediction only]; Region: COG3019 272560026075 Probable gene remnant. Similar to the N-terminal regions of Ralstonia solanacearum ISRso16-transposase OrfB protein Rsp0558 or Rs03921 SWALL:Q8XSC0 (EMBL:AL646079) (280 aa) fasta scores: E(): 1.4e-09, 56.25% id in 64 aa, and Yersinia pestis transposase ypcd1.94 SWALL:Q9RI05 (EMBL:AL117189) (269 aa) fasta scores: E(): 3.5e-06, 48.43% id in 64 aa; IS element protein (fragment) 272560026076 Transposase; Region: HTH_Tnp_1; cl17663 272560026077 Pfam match to entry PF01527 Transposase_8, Transposase , score 61.8, E-value 9.9e-16 272560026078 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560026079 Similar to C-terminal regions of Rhizobium meliloti transposase for insertion sequence element ISRm3 SWALL:TRA3_RHIME (SWALL:P80011) (400 aa) fasta scores: E(): 2.8e-24, 49% id in 151 aa, and Ralstonia solanacearum ISRso7-transposase TISRso7 or Rsp0478 or Rs00356 or Rsc0252 or Rs00687 SWALL:Q8XEN1 (EMBL:AL646078) (416 aa) fasta scores: E(): 3.7e-31, 54.81% id in 166 aa; transposase (fragment) 272560026080 Pfam match to entry PF00872 Transpo_mutator, Transposase, Mutator family , score 112.6, E-value 2.4e-32 272560026081 glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331 272560026082 Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans). The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714 272560026083 glutaminase active site [active] 272560026084 SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008 272560026085 dimer interface [polypeptide binding]; other site 272560026086 active site 272560026087 SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009 272560026088 dimer interface [polypeptide binding]; other site 272560026089 active site 272560026090 Pfam match to entry PF01380 SIS, SIS domain , score 103.7, E-value 2.3e-28 272560026091 Pfam match to entry PF01380 SIS, SIS domain , score 115.4, E-value 7.2e-32 272560026092 Pfam match to entry PF00310 GATase_2, Glutamine amidotransferases class-II , score 239.5, E-value 3.1e-69 272560026093 PS00443 Glutamine amidotransferases class-II active site. 272560026094 Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692 272560026095 1 probable transmembrane helix predicted for BPSS2011 by TMHMM2.0 at aa 49-68 272560026096 6 probable transmembrane helices predicted for BPSS2012 by TMHMM2.0 at aa 24-46, 89-111, 118-140, 173-195, 207-229 and 234-256 272560026097 Signal peptide predicted for BPSS2013 by SignalP 2.0 HMM (Signal peptide probability 0.930) with cleavage site probability 0.999 between residues 32 and 33; signal peptide 272560026098 Protein of unknown function (DUF342); Region: DUF342; cl19219 272560026099 Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215 272560026100 CESA_like is the cellulose synthase superfamily; Region: CESA_like; cd06423 272560026101 DXD motif; other site 272560026102 5 probable transmembrane helices predicted for BPSS2015 by TMHMM2.0 at aa 9-31, 96-118, 400-422, 437-459 and 472-494 272560026103 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 106.6, E-value 3.1e-29 272560026104 UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381 272560026105 Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786 272560026106 active site 272560026107 homodimer interface [polypeptide binding]; other site 272560026108 Pfam match to entry PF02350 Epimerase_2, UDP-N-acetylglucosamine 2-epimerase , score 571.9, E-value 2.7e-169 272560026109 transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062 272560026110 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026111 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560026112 dimerization interface [polypeptide binding]; other site 272560026113 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 37.2, E-value 2.5e-08 272560026114 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 66.7, E-value 3.1e-17 272560026115 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026116 Predicted helix-turn-helix motif with score 1012.000, SD 2.63 at aa 17-38, sequence GGFARAAGRLDMAVQTISAQVR 272560026117 Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861 272560026118 Pfam match to entry PF03741 TerC, Integral membrane protein TerC family , score 295.6, E-value 4e-86 272560026119 7 probable transmembrane helices predicted for BPSS2018 by TMHMM2.0 at aa 15-37, 56-78, 88-105, 135-157, 162-184, 191-210 and 220-239 272560026120 Transcription factor zinc-finger; Region: zf-TFIIB; cl01565 272560026121 Glutathione-dependent formaldehyde-activating enzyme; Region: GFA; pfam04828 272560026122 Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076 272560026123 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560026124 catalytic residue [active] 272560026125 Pfam match to entry PF00282 pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved domain , score -70.1, E-value 4.7e-08 272560026126 Signal peptide predicted for BPSS2022 by SignalP 2.0 HMM (Signal peptide probability 0.982) with cleavage site probability 0.631 between residues 21 and 22; signal peptide 272560026127 Bulb-type mannose-specific lectin. The domain contains a three-fold internal repeat (beta-prism architecture). The consensus sequence motif QXDXNXVXY is involved in alpha-D-mannose recognition. Lectins are carbohydrate-binding proteins which specifically...; Region: B_lectin; cd00028 272560026128 Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283 272560026129 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560026130 NAD binding site [chemical binding]; other site 272560026131 catalytic Zn binding site [ion binding]; other site 272560026132 structural Zn binding site [ion binding]; other site 272560026133 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 216.0, E-value 3.7e-62 272560026134 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560026135 Glutamate decarboxylase and related PLP-dependent proteins [Amino acid transport and metabolism]; Region: GadB; COG0076 272560026136 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560026137 catalytic residue [active] 272560026138 Pfam match to entry PF00282 pyridoxal_deC, Pyridoxal-dependent decarboxylase conserved domain , score -67.3, E-value 3.3e-08 272560026139 uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_2; cd07805 272560026140 N- and C-terminal domain interface [polypeptide binding]; other site 272560026141 Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070 272560026142 active site 272560026143 MgATP binding site [chemical binding]; other site 272560026144 catalytic site [active] 272560026145 metal binding site [ion binding]; metal-binding site 272560026146 xylulose binding site [chemical binding]; other site 272560026147 putative homodimer interface [polypeptide binding]; other site 272560026148 Pfam match to entry PF02782 FGGY_C, FGGY family of carbohydrate kinases, C-terminal domain , score 68.4, E-value 9.7e-18 272560026149 Pfam match to entry PF00370 FGGY, FGGY family of carbohydrate kinases, N-terminal domain , score 90.2, E-value 2.7e-24 272560026150 Signal peptide predicted for BPSS2027 by SignalP 2.0 HMM (Signal peptide probability 0.943) with cleavage site probability 0.937 between residues 39 and 40; signal peptide 272560026151 Transcriptional regulator [Transcription]; Region: AcrR; COG1309 272560026152 Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440 272560026153 Pfam match to entry PF00440 tetR, Bacterial regulatory proteins, tetR family , score 60.5, E-value 2.3e-15 272560026154 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560026155 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560026156 active site 272560026157 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 184.0, E-value 1.5e-52 272560026158 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 163.3, E-value 2.7e-46 272560026159 PS00072 Acyl-CoA dehydrogenases signature 1. 272560026160 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 72.5, E-value 5.8e-19 272560026161 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560026162 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560026163 NAD(P) binding site [chemical binding]; other site 272560026164 active site 272560026165 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 224.4, E-value 1.1e-64 272560026166 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799 272560026167 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172 272560026168 Pfam match to entry PF01039 Carboxyl_trans, Carboxyl transferase domain , score 460.7, E-value 8.2e-136 272560026169 Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960 272560026170 Acyl-CoA dehydrogenase; Region: ACAD; cl09933 272560026171 active site 272560026172 Pfam match to entry PF02771 Acyl-CoA_dh_N, Acyl-CoA dehydrogenase, N-terminal domain , score 91.8, E-value 8.7e-25 272560026173 Pfam match to entry PF02770 Acyl-CoA_dh_M, Acyl-CoA dehydrogenase, middle domain , score 170.5, E-value 1.8e-48 272560026174 PS00072 Acyl-CoA dehydrogenases signature 1. 272560026175 Pfam match to entry PF00441 Acyl-CoA_dh, Acyl-CoA dehydrogenase, C-terminal domain , score 188.8, E-value 5.7e-54 272560026176 PS00073 Acyl-CoA dehydrogenases signature 2. 272560026177 enoyl-CoA hydratase; Provisional; Region: PRK05995 272560026178 Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558 272560026179 substrate binding site [chemical binding]; other site 272560026180 oxyanion hole (OAH) forming residues; other site 272560026181 trimer interface [polypeptide binding]; other site 272560026182 Pfam match to entry PF00378 ECH, Enoyl-CoA hydratase/isomerase , score 99.8, E-value 3.4e-27 272560026183 Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism]; Region: COG4770 272560026184 Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289 272560026185 ATP-grasp domain; Region: ATP-grasp_4; cl17255 272560026186 Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785 272560026187 The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850 272560026188 carboxyltransferase (CT) interaction site; other site 272560026189 biotinylation site [posttranslational modification]; other site 272560026190 Pfam match to entry PF00289 CPSase_L_chain, Carbamoyl-phosphate synthase L chain, N-terminal domain , score 151.7, E-value 8.5e-43 272560026191 Pfam match to entry PF02786 CPSase_L_D2, Carbamoyl-phosphate synthase L chain, ATP binding domain , score 344.0, E-value 1.1e-100 272560026192 PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 272560026193 PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 272560026194 Pfam match to entry PF02785 Biotin_carb_C, Biotin carboxylase C-terminal domain , score 148.1, E-value 1e-41 272560026195 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 75.9, E-value 5.6e-20 272560026196 PS00188 Biotin-requiring enzymes attachment site. 272560026197 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 272560026198 Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022 272560026199 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560026200 acyl-activating enzyme (AAE) consensus motif; other site 272560026201 AMP binding site [chemical binding]; other site 272560026202 active site 272560026203 CoA binding site [chemical binding]; other site 272560026204 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 308.3, E-value 6.1e-90 272560026205 PS00455 AMP-binding domain signature. 272560026206 Signal peptide predicted for BPSS2037 by SignalP 2.0 HMM (Signal peptide probability 0.988) with cleavage site probability 0.655 between residues 26 and 27; signal peptide 272560026207 The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505 272560026208 Di-iron ligands [ion binding]; other site 272560026209 4 probable transmembrane helices predicted for BPSS2037 by TMHMM2.0 at aa 12-34, 38-60, 167-189 and 204-221 272560026210 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 88.6, E-value 8e-24 272560026211 Phosphopantetheine attachment site; Region: PKS_PP; smart00823 272560026212 Pfam match to entry PF00550 pp-binding, Phosphopantetheine attachment site , score 60.3, E-value 2.7e-15 272560026213 Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230 272560026214 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560026215 S-adenosylmethionine binding site [chemical binding]; other site 272560026216 Pfam match to entry PF02353 CMAS, Cyclopropane-fatty-acyl-phospholipid synthase , score 90.9, E-value 1.7e-24 272560026217 The Delta9 Fatty Acid Desaturase (Delta9-FADS)-like CD includes the delta-9 and delta-11 acyl CoA desaturases found in various eukaryotes including vertebrates, insects, higher plants, and fungi. The delta-9 acyl-lipid desaturases are found in a wide...; Region: Delta9-FADS-like; cd03505 272560026218 Di-iron ligands [ion binding]; other site 272560026219 5 probable transmembrane helices predicted for BPSS2040 by TMHMM2.0 at aa 52-71, 81-103, 116-135, 202-224 and 231-253 272560026220 Pfam match to entry PF00487 FA_desaturase, Fatty acid desaturase , score 86.1, E-value 4.7e-23 272560026221 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292 272560026222 active site 272560026223 acyl-CoA synthetase; Validated; Region: PRK05850 272560026224 Fatty acyl-AMP ligase (FAAL); Region: FAAL; cd05931 272560026225 acyl-activating enzyme (AAE) consensus motif; other site 272560026226 active site 272560026227 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 268.1, E-value 7.5e-78 272560026228 1 probable transmembrane helix predicted for BPSS2042 by TMHMM2.0 at aa 72-94 272560026229 PS00455 AMP-binding domain signature. 272560026230 PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443 272560026231 CoenzymeA binding site [chemical binding]; other site 272560026232 subunit interaction site [polypeptide binding]; other site 272560026233 PHB binding site; other site 272560026234 Pfam match to entry PF02584 DUF157, Uncharacterized protein PaaI, COG2050 , score 49.9, E-value 3.6e-12 272560026235 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560026236 nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052 272560026237 ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424 272560026238 dimer interface [polypeptide binding]; other site 272560026239 ADP-ribose binding site [chemical binding]; other site 272560026240 active site 272560026241 nudix motif; other site 272560026242 metal binding site [ion binding]; metal-binding site 272560026243 Pfam match to entry PF00293 NUDIX, NUDIX domain , score 60.8, E-value 2e-15 272560026244 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026245 DDE domain; Region: DDE_Tnp_IS240; pfam13610 272560026246 Pfam match to entry PF00665 rve, Integrase core domain , score 18.9, E-value 1.9e-05 272560026247 N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228 272560026248 Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281 272560026249 active site 272560026250 Pfam match to entry PF01685 ATZ_TRZ, Chlorohydrolase , score 194.2, E-value 1.3e-55 272560026251 Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625 272560026252 GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047 272560026253 putative C-terminal domain interface [polypeptide binding]; other site 272560026254 putative GSH binding site (G-site) [chemical binding]; other site 272560026255 putative dimer interface [polypeptide binding]; other site 272560026256 C-terminal, alpha helical domain of an unknown subfamily 2 of Glutathione S-transferases; Region: GST_C_2; cd03180 272560026257 putative N-terminal domain interface [polypeptide binding]; other site 272560026258 putative dimer interface [polypeptide binding]; other site 272560026259 putative substrate binding pocket (H-site) [chemical binding]; other site 272560026260 Pfam match to entry PF02798 GST_N, Glutathione S-transferase, N-terminal domain , score 51.0, E-value 1.8e-12 272560026261 Pfam match to entry PF00043 GST_C, Glutathione S-transferase, C-terminal domain , score 24.0, E-value 1.1e-06 272560026262 DDE domain; Region: DDE_Tnp_IS240; pfam13610 272560026263 Pfam match to entry PF00665 rve, Integrase core domain , score 16.2, E-value 0.00011 272560026264 No significant database matches. Feature lacks a translation stop codon. Possible remnant of gene disrupted by IS element insertion;hypothetical protein (fragment) 272560026265 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677 272560026266 Domain of Unknown Function (DUF746); Region: DUF746; pfam05344 272560026267 Domain of Unknown Function (DUF746); Region: DUF746; pfam05344 272560026268 Predicted helix-turn-helix motif with score 1436.000, SD 4.08 at aa 254-275, sequence LSVMQAADLVGTSHGIIHKWLR 272560026269 Genomic island GI 16 272560026270 Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831 272560026271 POTRA domain, ShlB-type; Region: POTRA_2; pfam08479 272560026272 Pfam match to entry PF03865 HlyB, Hemolysin activator HlyB , score -110.7, E-value 1.6e-10 272560026273 Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018 272560026274 haemagglutination activity domain; Region: Haemagg_act; pfam05860 272560026275 Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210 272560026276 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 272560026277 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 272560026278 Haemagluttinin repeat; Region: Fil_haemagg_2; pfam13332 272560026279 Colicin C terminal ribonuclease domain; Region: Colicin_C; pfam12106 272560026280 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 272560026281 RHS Repeat; Region: RHS_repeat; pfam05593 272560026282 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026283 RHS Repeat; Region: RHS_repeat; pfam05593 272560026284 RHS Repeat; Region: RHS_repeat; pfam05593 272560026285 RHS Repeat; Region: RHS_repeat; pfam05593 272560026286 RHS Repeat; Region: RHS_repeat; pfam05593 272560026287 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026288 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026289 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026290 RHS Repeat; Region: RHS_repeat; pfam05593 272560026291 RHS protein; Region: RHS; pfam03527 272560026292 RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696 272560026293 SCP1.201-like deaminase; Region: SCP1201-deam; pfam14428 272560026294 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560026295 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560026296 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560026297 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3464 272560026298 zinc-finger of transposase IS204/IS1001/IS1096/IS1165; Region: zf-ISL3; pfam14690 272560026299 Helix-turn-helix domain of transposase family ISL3; Region: HTH_Tnp_ISL3; pfam13542 272560026300 Transposase; Region: DDE_Tnp_ISL3; pfam01610 272560026301 Pfam match to entry PF01610 Transposase_12, Transposase , score 371.8, E-value 4.5e-109 272560026302 Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301 272560026303 Signal peptide predicted for BPSS2058 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.572 between residues 29 and 30; signal peptide 272560026304 Pfam match to entry PF00375 SDF, Sodium:dicarboxylate symporter family , score 84.1, E-value 1.3e-22 272560026305 3 probable transmembrane helices predicted for BPSS2058 by TMHMM2.0 at aa 7-29, 44-66 and 85-107 272560026306 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026307 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 272560026308 homotrimer interaction site [polypeptide binding]; other site 272560026309 putative active site [active] 272560026310 Pfam match to entry PF01042 UPF0076, YjgF family , score 134.3, E-value 1.4e-37 272560026311 Signal peptide predicted for BPSS2060 by SignalP 2.0 HMM (Signal peptide probability 0.841) with cleavage site probability 0.613 between residues 19 and 20; signal peptide 272560026312 Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964 272560026313 active site 272560026314 homotetramer interface [polypeptide binding]; other site 272560026315 homodimer interface [polypeptide binding]; other site 272560026316 Pfam match to entry PF00710 Asparaginase, Asparaginase , score 414.5, E-value 6.2e-122 272560026317 PS00917 Asparaginase / glutaminase active site signature 2. 272560026318 PS00144 Asparaginase / glutaminase active site signature 1. 272560026319 Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964 272560026320 YheO-like PAS domain; Region: PAS_6; pfam08348 272560026321 HTH domain; Region: HTH_22; pfam13309 272560026322 Predicted helix-turn-helix motif with score 1581.000, SD 4.57 at aa 193-214, sequence RSMETVAQHLGVSRATVYNDAK 272560026323 Similar to the C-terminal region of Vibrio cholerae transposase SWALL:O68334 (EMBL:AF034434) (325 aa) fasta scores: E(): 1.3e-16, 42.96% id in 135 aa. Feature contains a frameshift after codon 68; transposase (fragment) 272560026324 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560026325 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560026326 Coenzyme A binding pocket [chemical binding]; other site 272560026327 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 42.6, E-value 5.7e-10 272560026328 Transposase IS66 family; Region: DDE_Tnp_IS66; pfam03050 272560026329 IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817 272560026330 Signal peptide predicted for BPSS2064 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 21 and 22; signal peptide 272560026331 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560026332 trimer interface [polypeptide binding]; other site 272560026333 eyelet of channel; other site 272560026334 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -126.4, E-value 0.3 272560026335 Alpha-Ketoglutaric Semialdehyde Dehydrogenase; Region: ALDH_KGSADH; cd07129 272560026336 dimer interface [polypeptide binding]; other site 272560026337 NADP binding site [chemical binding]; other site 272560026338 catalytic residues [active] 272560026339 Pfam match to entry PF00171 aldedh, Aldehyde dehydrogenase , score -75.4, E-value 1.7e-12 272560026340 PS00070 Aldehyde dehydrogenases cysteine active site. 272560026341 Fumarylacetoacetate (FAA) hydrolase family protein [General function prediction only]; Region: COG3970 272560026342 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560026343 aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021 272560026344 active site 272560026345 catalytic residues [active] 272560026346 Pfam match to entry PF01263 Aldose_epim, Aldose 1-epimerase , score 73.1, E-value 3.7e-19 272560026347 short chain dehydrogenase; Provisional; Region: PRK12827 272560026348 classical (c) SDRs; Region: SDR_c; cd05233 272560026349 NAD(P) binding site [chemical binding]; other site 272560026350 active site 272560026351 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 188.7, E-value 6.2e-54 272560026352 ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411 272560026353 First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216 272560026354 Walker A/P-loop; other site 272560026355 ATP binding site [chemical binding]; other site 272560026356 Q-loop/lid; other site 272560026357 ABC transporter signature motif; other site 272560026358 Walker B; other site 272560026359 D-loop; other site 272560026360 H-loop/switch region; other site 272560026361 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 163.5, E-value 2.4e-46 272560026362 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026363 Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579 272560026364 TM-ABC transporter signature motif; other site 272560026365 Pfam match to entry PF02653 BPD_transp_2, Branched-chain amino acid transport system / permease component , score -8.6, E-value 2.7e-06 272560026366 8 probable transmembrane helices predicted for BPSS2070 by TMHMM2.0 at aa 15-37, 44-66, 86-108, 121-143, 165-187, 212-234, 249-271 and 284-306 272560026367 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879 272560026368 Signal peptide predicted for BPSS2071 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.997 between residues 27 and 28; signal peptide 272560026369 Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312 272560026370 putative ligand binding site [chemical binding]; other site 272560026371 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948 272560026372 Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316 272560026373 active site pocket [active] 272560026374 Pfam match to entry PF01188 MR_MLE, Mandelate racemase / muconate lactonizing enzyme, C-terminal domain , score 74.4, E-value 1.5e-19 272560026375 Pfam match to entry PF02746 MR_MLE_N, Mandelate racemase / muconate lactonizing enzyme, N-terminal domain , score 59.1, E-value 6.1e-15 272560026376 Predicted transcriptional regulators [Transcription]; Region: COG1725 272560026377 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377 272560026378 DNA-binding site [nucleotide binding]; DNA binding site 272560026379 This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895 272560026380 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 53.4, E-value 3.3e-13 272560026381 Predicted helix-turn-helix motif with score 1206.000, SD 3.29 at aa 58-79, sequence PSEGEFAQKLGVGRGVVREAFK 272560026382 SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450 272560026383 Pfam match to entry PF03758 SMP-30, Senescence marker protein-30 (SMP-30) , score 201.5, E-value 8.5e-58 272560026384 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560026385 Gene remnant. Similar to internal regions of Ralstonia solanacearum probable activation/secretion protein rsc0888 or rs06118 SWALL:Q8Y105 (EMBL:AL646061) (590 aa) fasta scores: E(): 5.1e-05, 55.55% id in 54 aa, and Ralstonia solanacearum probable activation/secretion signal peptide protein rsp0550 or rs06123 SWALL:Q8XSC8 (EMBL:AL646079) (590 aa) fasta scores: E(): 5.9e-05, 64.44% id in 45 aa;conserved hypothetical protein (fragment) 272560026386 Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929 272560026387 Similar to Escherichia coli hypothetical protein L0015 SWALL:O85621 (EMBL:AF071034) (512 aa) fasta scores: E(): 2e-99, 54.81% id in 509 aa, and to Shigella flexneri conserved hypothetical protein sf0860 SWALL:AAN42493 (EMBL:AE015115) (533 aa) fasta scores: E(): 2.7e-85, 49.07% id in 538 aa. Contains a frameshift after codon 430;transposase IS66 family protein (pseudogene) 272560026388 Pfam match to entry PF03050 Transposase_25, Transposase IS66 family , score 407.2, E-value 1e-119 272560026389 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3436 272560026390 IS66 Orf2 like protein; Region: TnpB_IS66; pfam05717 272560026391 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 272560026392 Transposase; Region: HTH_Tnp_1; cl17663 272560026393 Predicted helix-turn-helix motif with score 1180.000, SD 3.21 at aa 38-59, sequence ISVARLAMEHGVNPNRVFKWRR 272560026394 Alpha-galactosidase [Carbohydrate transport and metabolism]; Region: GalA; COG3345 272560026395 Melibiase; Region: Melibiase; pfam02065 272560026396 PS00512 Alpha-galactosidase signature. 272560026397 ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395 272560026398 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560026399 dimer interface [polypeptide binding]; other site 272560026400 conserved gate region; other site 272560026401 putative PBP binding loops; other site 272560026402 ABC-ATPase subunit interface; other site 272560026403 5 probable transmembrane helices predicted for BPSS2082 by TMHMM2.0 at aa 53-75, 80-102, 117-139, 160-182 and 216-238 272560026404 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 64.8, E-value 1.2e-16 272560026405 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560026406 ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177 272560026407 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560026408 dimer interface [polypeptide binding]; other site 272560026409 conserved gate region; other site 272560026410 putative PBP binding loops; other site 272560026411 ABC-ATPase subunit interface; other site 272560026412 6 probable transmembrane helices predicted for BPSS2083 by TMHMM2.0 at aa 33-55, 94-116, 129-148, 179-201, 222-244 and 285-307 272560026413 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 48.6, E-value 9.3e-12 272560026414 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560026415 Signal peptide predicted for BPSS2084 by SignalP 2.0 HMM (Signal peptide probability 0.943) with cleavage site probability 0.929 between residues 37 and 38; signal peptide 272560026416 ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653 272560026417 Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547 272560026418 Pfam match to entry PF01547 SBP_bac_1, Bacterial extracellular solute-binding protein , score 236.2, E-value 3e-68 272560026419 maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000 272560026420 The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301 272560026421 Walker A/P-loop; other site 272560026422 ATP binding site [chemical binding]; other site 272560026423 Q-loop/lid; other site 272560026424 ABC transporter signature motif; other site 272560026425 Walker B; other site 272560026426 D-loop; other site 272560026427 H-loop/switch region; other site 272560026428 Pfam match to entry PF03459 TOBE, TOBE domain , score 24.2, E-value 1.7e-06 272560026429 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 194.6, E-value 1e-55 272560026430 PS00211 ABC transporters family signature. 272560026431 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026432 Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086 272560026433 PS00430 TonB-dependent receptor proteins signature 1. 272560026434 Transcriptional regulators [Transcription]; Region: PurR; COG1609 272560026435 Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392 272560026436 DNA binding site [nucleotide binding] 272560026437 domain linker motif; other site 272560026438 Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267 272560026439 dimerization interface [polypeptide binding]; other site 272560026440 ligand binding site [chemical binding]; other site 272560026441 Pfam match to entry PF00532 Peripla_BP_like, Periplasmic binding proteins and sugar binding domain of the LacI family , score 51.6, E-value 1.1e-12 272560026442 PS00142 Neutral zinc metallopeptidases, zinc-binding region signature. 272560026443 Predicted helix-turn-helix motif with score 1775.000, SD 5.23 at aa 4-25, sequence ITSIQVAQLAGVSRTTVSFVLN 272560026444 Gene remnant. Similar to internal regions of Pseudomonas aeruginosa transposase for transposon Tn501 TnpA SWALL:TNP5_PSEAE (SWALL:P06695) (988 aa) fasta scores: E(): 3.7e-15, 59.3% id in 86 aa, and Shigella flexneri Tn501 transposition transposase TnpA SWALL:AAK18584 (EMBL:AF348706) (988 aa) fasta scores: E(): 3.7e-15, 59.3% id in 86 aa;transposase (fragment) 272560026445 Pfam match to entry PF01526 Transposase_7, Transposase , score 47.1, E-value 3.3e-13 272560026446 Signal peptide predicted for BPSS2089 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.960 between residues 25 and 26; signal peptide 272560026447 Domain of Unknown Function (DUF746); Region: DUF746; pfam05344 272560026448 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677 272560026449 Domain of Unknown Function (DUF746); Region: DUF746; pfam05344 272560026450 Predicted helix-turn-helix motif with score 1068.000, SD 2.82 at aa 141-162, sequence LLVMQVADLVGTSHGMVRKWHS 272560026451 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026452 Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209 272560026453 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026454 YD repeat (two copies); Region: YD_repeat_2x; TIGR01643 272560026455 RHS Repeat; Region: RHS_repeat; pfam05593 272560026456 Probable gene remnant. No significant database matches to the full length CDS. N-terminus is similar to the N-terminal region of Yersinia pestis hypothetical protein ypo0763 SWALL:Q8ZHW6 (EMBL:AJ414144) (439 aa) fasta scores: E(): 1.4e-29, 40.09% id in 212 aa. Similar to the N-terminal region of BPSS2055, 71.689% identity (72.018% ungapped) in 219 aa overlap;hypothetical protein (fragment) 272560026457 type VI secretion system Vgr family protein; Region: VI_Rhs_Vgr; TIGR03361 272560026458 Phage late control gene D protein (GPD); Region: Phage_GPD; pfam05954 272560026459 Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717 272560026460 Gp5 C-terminal repeat (3 copies); Region: Gp5_C; pfam06715 272560026461 type VI secretion ATPase, ClpV1 family; Region: VI_ClpV1; TIGR03345 272560026462 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560026463 Walker A motif; other site 272560026464 ATP binding site [chemical binding]; other site 272560026465 Walker B motif; other site 272560026466 arginine finger; other site 272560026467 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560026468 Walker A motif; other site 272560026469 ATP binding site [chemical binding]; other site 272560026470 Walker B motif; other site 272560026471 C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086 272560026472 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026473 Pfam match to entry PF00004 AAA, ATPase associated with various cellular activities (AAA) , score 34.0, E-value 1.6e-07 272560026474 PS00870 Chaperonins clpA/B signature 1. 272560026475 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026476 Protein of unknown function (DUF1305); Region: DUF1305; pfam06996 272560026477 type VI secretion protein, VC_A0110 family; Region: VI_chp_6; TIGR03359 272560026478 Gene 25-like lysozyme; Region: GPW_gp25; cl01403 272560026479 Protein of unknown function (DUF796); Region: DUF796; pfam05638 272560026480 type VI secretion protein, EvpB/VC_A0108 family; Region: VI_chp_2; TIGR03355 272560026481 Protein of unknown function (DUF770); Region: DUF770; pfam05591 272560026482 type VI secretion-associated protein, ImpA family; Region: VI_chp_8; TIGR03363 272560026483 Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220 272560026484 Catalytic domain of Protein Kinases; Region: PKc; cd00180 272560026485 active site 272560026486 ATP binding site [chemical binding]; other site 272560026487 substrate binding site [chemical binding]; other site 272560026488 activation loop (A-loop); other site 272560026489 1 probable transmembrane helix predicted for BPSS2102 by TMHMM2.0 at aa 633-655 272560026490 Pfam match to entry PF00069 pkinase, Protein kinase domain , score 93.6, E-value 2.6e-25 272560026491 PS00109 Tyrosine protein kinases specific active-site signature. 272560026492 PS00107 Protein kinases ATP-binding region signature. 272560026493 Uncharacterized protein conserved in bacteria (DUF2094); Region: DUF2094; pfam09867 272560026494 Signal peptide predicted for BPSS2104 by SignalP 2.0 HMM (Signal peptide probability 0.899) with cleavage site probability 0.441 between residues 40 and 41; signal peptide 272560026495 type VI secretion protein IcmF; Region: VI_IcmF; TIGR03348 272560026496 Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882 272560026497 G1 box; other site 272560026498 GTP/Mg2+ binding site [chemical binding]; other site 272560026499 G2 box; other site 272560026500 G3 box; other site 272560026501 Switch II region; other site 272560026502 ImcF-related N-terminal domain; Region: ImcF-related_N; pfam14331 272560026503 G4 box; other site 272560026504 Intracellular multiplication and human macrophage-killing; Region: IcmF-related; pfam06761 272560026505 Protein of unknown function (DUF1215); Region: DUF1215; pfam06744 272560026506 3 probable transmembrane helices predicted for BPSS2104 by TMHMM2.0 at aa 17-39, 49-68 and 470-488 272560026507 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026508 hypothetical protein; Provisional; Region: PRK07033 272560026509 Uncharacterized protein conserved in bacteria (DUF2077); Region: DUF2077; pfam09850 272560026510 Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185 272560026511 ligand binding site [chemical binding]; other site 272560026512 Pfam match to entry PF00691 OmpA, OmpA family , score 89.7, E-value 3.9e-24 272560026513 1 probable transmembrane helix predicted for BPSS2105 by TMHMM2.0 at aa 216-238 272560026514 Bacterial protein of unknown function (DUF876); Region: DUF876; pfam05936 272560026515 PS00215 Mitochondrial energy transfer proteins signature. 272560026516 Signal peptide predicted for BPSS2107 by SignalP 2.0 HMM (Signal peptide probability 0.996) with cleavage site probability 0.452 between residues 28 and 29; signal peptide 272560026517 Type VI secretion lipoprotein; Region: T6SS-SciN; pfam12790 272560026518 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560026519 outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302 272560026520 type VI secretion system FHA domain protein; Region: VI_FHA; TIGR03354 272560026521 Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060 272560026522 phosphopeptide binding site; other site 272560026523 Pfam match to entry PF00498 FHA, FHA domain , score 29.2, E-value 6.1e-06 272560026524 Signal peptide predicted for BPSS2110 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.554 between residues 22 and 23; signal peptide 272560026525 Domain of Unknown Function with PDB structure (DUF3857); Region: DUF3857; pfam12969 272560026526 Transglutaminase-like superfamily; Region: Transglut_core; pfam01841 272560026527 PS00210 Arthropod hemocyanins / insect LSPs signature 2. 272560026528 hypothetical protein; Provisional; Region: PRK07538 272560026529 geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032 272560026530 Pfam match to entry PF01360 Monooxygenase, Monooxygenase , score 92.4, E-value 5.9e-25 272560026531 Similar to Bordetella pertussis hypothetical protein SWALL:Q7VZD6 (EMBL:BX640413) (190 aa) fasta scores: E(): 4e-18, 39.22% id in 181 aa, and to Bordetella parapertussis hypothetical protein SWALL:Q7WAC9 (EMBL:BX640427) (190 aa) fasta scores: E(): 4e-18, 39.22% id in 181 aa. CDS contains frameshifts after codons 9 and 92;conserved hypothetical protein (pseudogene) 272560026532 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565 272560026533 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560026534 NAD(P) binding site [chemical binding]; other site 272560026535 active site 272560026536 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 119.1, E-value 5.4e-33 272560026537 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560026538 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026539 The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432 272560026540 dimerization interface [polypeptide binding]; other site 272560026541 substrate binding pocket [chemical binding]; other site 272560026542 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 82.3, E-value 6.4e-22 272560026543 Predicted helix-turn-helix motif with score 1579.000, SD 4.56 at aa 30-51, sequence LNFRAAADEIGVTQGAVAQQVR 272560026544 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026545 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 116.8, E-value 2.7e-32 272560026546 D-serine dehydratase; Provisional; Region: PRK02991 272560026547 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560026548 catalytic residue [active] 272560026549 Pfam match to entry PF00291 PALP, Pyridoxal-phosphate dependent enzyme , score 98.2, E-value 1.1e-26 272560026550 DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139 272560026551 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026552 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560026553 dimerization interface [polypeptide binding]; other site 272560026554 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 96.3, E-value 4e-26 272560026555 Predicted helix-turn-helix motif with score 2251.000, SD 6.85 at aa 23-44, sequence GSFTKAADALHLTQSAISQQIR 272560026556 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026557 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 77.3, E-value 2.1e-20 272560026558 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560026559 dimerization interface [polypeptide binding]; other site 272560026560 putative DNA binding site [nucleotide binding]; other site 272560026561 putative Zn2+ binding site [ion binding]; other site 272560026562 Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158 272560026563 active site residue [active] 272560026564 Pfam match to entry PF00581 Rhodanese, Rhodanese-like domain , score 58.1, E-value 1.2e-14 272560026565 PS00380 Rhodanese signature 1. 272560026566 Pfam match to entry PF01022 HTH_5, Bacterial regulatory protein, arsR family , score 64.7, E-value 1.3e-16 272560026567 Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491 272560026568 Pfam match to entry PF00753 lactamase_B, Metallo-beta-lactamase superfamily , score 79.1, E-value 5.9e-21 272560026569 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026570 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560026571 putative substrate translocation pore; other site 272560026572 10 probable transmembrane helices predicted for BPSS2120 by TMHMM2.0 at aa 21-40, 55-77, 90-109, 114-136, 149-171, 181-200, 301-320, 325-347, 360-382 and 386-408 272560026573 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -83.6, E-value 6.8e-05 272560026574 PS00216 Sugar transport proteins signature 1. 272560026575 PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2. 272560026576 PS00216 Sugar transport proteins signature 1. 272560026577 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104 272560026578 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560026579 catalytic residue [active] 272560026580 Pfam match to entry PF00266 aminotran_5, Aminotransferase class-V , score 362.1, E-value 3.9e-106 272560026581 PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 272560026582 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026583 metabolite-proton symporter; Region: 2A0106; TIGR00883 272560026584 putative substrate translocation pore; other site 272560026585 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 82.0, E-value 7.9e-22 272560026586 11 probable transmembrane helices predicted for BPSS2123 by TMHMM2.0 at aa 7-29, 44-66, 78-100, 143-165, 172-194, 224-246, 253-275, 295-314, 321-343, 358-380 and 387-409 272560026587 putative choline sulfate-utilization transcription factor; Region: chol_sulf_TF; TIGR03418 272560026588 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026589 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560026590 dimerization interface [polypeptide binding]; other site 272560026591 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 76.9, E-value 2.7e-20 272560026592 Predicted helix-turn-helix motif with score 1265.000, SD 3.50 at aa 27-48, sequence GTFERAAEELCVTGSAVAKRVA 272560026593 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026594 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 80.0, E-value 3.2e-21 272560026595 Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809 272560026596 FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070 272560026597 active site 272560026598 substrate binding site [chemical binding]; other site 272560026599 FMN binding site [chemical binding]; other site 272560026600 putative catalytic residues [active] 272560026601 Pfam match to entry PF01070 FMN_dh, FMN-dependent dehydrogenase , score 593.2, E-value 1e-175 272560026602 PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 272560026603 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179 272560026604 Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557 272560026605 Pfam match to entry PF01557 FAA_hydrolase, Fumarylacetoacetate (FAA) hydrolase , score 276.5, E-value 2.3e-80 272560026606 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560026607 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560026608 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560026609 Predicted helix-turn-helix motif with score 1335.000, SD 3.73 at aa 46-67, sequence LTRTEITKELGRNASEIYRMLE 272560026610 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 4.7, E-value 1e-08 272560026611 indole acetimide hydrolase; Validated; Region: PRK07488 272560026612 Pfam match to entry PF01425 Amidase, Amidase , score 362.8, E-value 2.4e-106 272560026613 acetyl coenzyme A synthetase (ADP forming), alpha domain; Region: AcCoA-syn-alpha; TIGR02717 272560026614 CoA binding domain; Region: CoA_binding_2; pfam13380 272560026615 Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607 272560026616 ATP-grasp domain; Region: ATP-grasp_5; pfam13549 272560026617 Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302 272560026618 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560026619 Coenzyme A binding pocket [chemical binding]; other site 272560026620 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 43.3, E-value 3.5e-10 272560026621 Pfam match to entry PF02629 CoA_binding, CoA binding domain , score 15.7, E-value 1.7e-06 272560026622 H-NS histone family; Region: Histone_HNS; pfam00816 272560026623 NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961 272560026624 Domain in histone-like proteins of HNS family; Region: HNS; cl19571 272560026625 The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102 272560026626 transcriptional regulatory protein ZraR; Provisional; Region: PRK10365 272560026627 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560026628 putative active site [active] 272560026629 heme pocket [chemical binding]; other site 272560026630 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560026631 Walker A motif; other site 272560026632 ATP binding site [chemical binding]; other site 272560026633 Walker B motif; other site 272560026634 arginine finger; other site 272560026635 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560026636 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 38.8, E-value 8.2e-09 272560026637 Predicted helix-turn-helix motif with score 1093.000, SD 2.91 at aa 479-500, sequence GKVTEAAARIGIGRATFYKKLA 272560026638 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560026639 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 427.7, E-value 6.9e-126 272560026640 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560026641 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560026642 Signal peptide predicted for BPSS2133 by SignalP 2.0 HMM (Signal peptide probability 0.763) with cleavage site probability 0.372 between residues 31 and 32; signal peptide 272560026643 H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610 272560026644 9 probable transmembrane helices predicted for BPSS2133 by TMHMM2.0 at aa 7-29, 49-68, 88-110, 163-185, 219-241, 269-291, 304-335, 350-372 and 430-452 272560026645 Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586 272560026646 GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444 272560026647 active site residue [active] 272560026648 Pfam match to entry PF00597 DedA, DedA family , score 29.0, E-value 7.3e-06 272560026649 4 probable transmembrane helices predicted for BPSS2135 by TMHMM2.0 at aa 13-35, 50-72, 136-158 and 173-191 272560026650 Signal peptide predicted for BPSS2136 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.912 between residues 28 and 29; signal peptide 272560026651 outer membrane porin, OprD family; Region: OprD; pfam03573 272560026652 Pfam match to entry PF03573 Peptidase_S43, Peptidase S43 , score 98.0, E-value 1.2e-26 272560026653 Signal peptide predicted for BPSS2137 by SignalP 2.0 HMM (Signal peptide probability 0.825) with cleavage site probability 0.308 between residues 29 and 30; signal peptide 272560026654 oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079 272560026655 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560026656 Walker A/P-loop; other site 272560026657 ATP binding site [chemical binding]; other site 272560026658 Q-loop/lid; other site 272560026659 ABC transporter signature motif; other site 272560026660 Walker B; other site 272560026661 D-loop; other site 272560026662 H-loop/switch region; other site 272560026663 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560026664 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 217.7, E-value 1.2e-62 272560026665 PS00211 ABC transporters family signature. 272560026666 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026667 oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473 272560026668 ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257 272560026669 Walker A/P-loop; other site 272560026670 ATP binding site [chemical binding]; other site 272560026671 Q-loop/lid; other site 272560026672 ABC transporter signature motif; other site 272560026673 Walker B; other site 272560026674 D-loop; other site 272560026675 H-loop/switch region; other site 272560026676 Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097 272560026677 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 231.1, E-value 1e-66 272560026678 PS00211 ABC transporters family signature. 272560026679 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026680 N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911 272560026681 oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406 272560026682 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560026683 dimer interface [polypeptide binding]; other site 272560026684 conserved gate region; other site 272560026685 putative PBP binding loops; other site 272560026686 ABC-ATPase subunit interface; other site 272560026687 6 probable transmembrane helices predicted for BPSS2139 by TMHMM2.0 at aa 36-58, 106-128, 141-158, 162-181, 212-234 and 266-288 272560026688 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 53.6, E-value 2.9e-13 272560026689 oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471 272560026690 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560026691 dimer interface [polypeptide binding]; other site 272560026692 conserved gate region; other site 272560026693 putative PBP binding loops; other site 272560026694 ABC-ATPase subunit interface; other site 272560026695 6 probable transmembrane helices predicted for BPSS2140 by TMHMM2.0 at aa 9-31, 99-121, 134-156, 176-195, 238-260 and 280-299 272560026696 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 22.1, E-value 0.0004 272560026697 PS00402 Binding-protein-dependent transport systems inner membrane comp. sign. 272560026698 Signal peptide predicted for BPSS2141 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.639 between residues 39 and 40; signal peptide 272560026699 The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504 272560026700 ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166 272560026701 peptide binding site [polypeptide binding]; other site 272560026702 Pfam match to entry PF00496 SBP_bac_5, Bacterial extracellular solute-binding proteins, family 5 , score 404.2, E-value 8.3e-119 272560026703 1 probable transmembrane helix predicted for BPSS2141 by TMHMM2.0 at aa 21-43 272560026704 DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943 272560026705 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560026706 non-specific DNA binding site [nucleotide binding]; other site 272560026707 salt bridge; other site 272560026708 sequence-specific DNA binding site [nucleotide binding]; other site 272560026709 Cupin domain; Region: Cupin_2; pfam07883 272560026710 Pfam match to entry PF01381 HTH_3, Helix-turn-helix , score 54.7, E-value 1.3e-13 272560026711 Predicted helix-turn-helix motif with score 1518.000, SD 4.36 at aa 30-51, sequence RTLDETATAAGISKPFLSQVER 272560026712 Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104 272560026713 POT family; Region: PTR2; cl17359 272560026714 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026715 putative substrate translocation pore; other site 272560026716 14 probable transmembrane helices predicted for BPSS2143 by TMHMM2.0 at aa 20-37, 47-69, 78-95, 100-117, 138-160, 165-187, 208-227, 232-254, 261-283, 314-336, 349-371, 381-403, 415-437 and 452-474 272560026717 Pfam match to entry PF00854 PTR2, POT family , score 149.3, E-value 4.5e-42 272560026718 Signal peptide predicted for BPSS2144 by SignalP 2.0 HMM (Signal peptide probability 0.891) with cleavage site probability 0.358 between residues 31 and 32; signal peptide 272560026719 Signal peptide predicted for BPSS2145 by SignalP 2.0 HMM (Signal peptide probability 0.995) with cleavage site probability 0.521 between residues 33 and 34; signal peptide 272560026720 Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992 272560026721 PS00213 Lipocalin signature. 272560026722 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560026723 leucine transcriptional activator; Reviewed; Region: leuO; PRK09508 272560026724 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026725 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 272560026726 substrate binding pocket [chemical binding]; other site 272560026727 dimerization interface [polypeptide binding]; other site 272560026728 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 95.8, E-value 5.5e-26 272560026729 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 60.9, E-value 1.8e-15 272560026730 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026731 Predicted helix-turn-helix motif with score 1128.000, SD 3.03 at aa 45-66, sequence RQVTRAGQRIGLTQPAVSNALG 272560026732 Probable gene remnant. Similar to the C-terminal region of Streptomyces coelicolor hypothetical protein sco6307 or scif3.09C SWALL:Q93RT4 (EMBL:AL939127) (320 aa) fasta scores: E(): 3e-07, 43.21% id in 81 aa. Similar to the C-terminal region of BPSS2156, 98.810% identity (98.810% ungapped) in 84 aa overlap;conserved hypothetical protein (fragment) 272560026733 putative transposase OrfB; Reviewed; Region: PHA02517 272560026734 HTH-like domain; Region: HTH_21; pfam13276 272560026735 Integrase core domain; Region: rve; pfam00665 272560026736 Integrase core domain; Region: rve_3; pfam13683 272560026737 Pfam match to entry PF00665 rve, Integrase core domain , score 147.9, E-value 1.1e-41 272560026738 Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963 272560026739 Transposase; Region: HTH_Tnp_1; cl17663 272560026740 MmgE/PrpD family; Region: MmgE_PrpD; cl00912 272560026741 Pfam match to entry PF03972 MmgE_PrpD, MmgE/PrpD family , score 239.6, E-value 3e-69 272560026742 Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301 272560026743 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560026744 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 223.9, E-value 1.6e-64 272560026745 NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604 272560026746 Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912 272560026747 NAD(P) binding site [chemical binding]; other site 272560026748 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score -39.1, E-value 7e-05 272560026749 Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431 272560026750 catalytic triad [active] 272560026751 conserved cis-peptide bond; other site 272560026752 Pfam match to entry PF00857 Isochorismatase, Isochorismatase , score 138.1, E-value 1e-38 272560026753 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026754 Major Facilitator Superfamily; Region: MFS_1; pfam07690 272560026755 putative substrate translocation pore; other site 272560026756 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -109.0, E-value 0.00052 272560026757 14 probable transmembrane helices predicted for BPSS2154 by TMHMM2.0 at aa 28-50, 65-87, 94-113, 123-145, 157-179, 183-205, 226-248, 252-269, 290-309, 324-346, 353-372, 376-398, 419-441 and 446-468 272560026758 benzoate transport; Region: 2A0115; TIGR00895 272560026759 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026760 putative substrate translocation pore; other site 272560026761 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score 94.9, E-value 1e-25 272560026762 12 probable transmembrane helices predicted for BPSS2155 by TMHMM2.0 at aa 21-43, 69-91, 98-120, 124-146, 158-180, 190-207, 280-302, 312-334, 341-360, 364-381, 401-423 and 428-450 272560026763 PS00216 Sugar transport proteins signature 1. 272560026764 Putative cyclase; Region: Cyclase; pfam04199 272560026765 Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804 272560026766 Pfam match to entry PF02515 CAIB-BAIF, CAIB/BAIF family , score 185.4, E-value 6.1e-53 272560026767 IclR helix-turn-helix domain; Region: HTH_IclR; cl17605 272560026768 Transcriptional regulator [Transcription]; Region: IclR; COG1414 272560026769 Bacterial transcriptional regulator; Region: IclR; pfam01614 272560026770 Pfam match to entry PF01614 IclR, Bacterial transcriptional regulator , score 95.7, E-value 6.1e-26 272560026771 PS01051 Bacterial regulatory proteins, iclR family signature. 272560026772 Predicted helix-turn-helix motif with score 1506.000, SD 4.32 at aa 29-50, sequence LTLAQVSEASGVNMSTLLRMFE 272560026773 Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301 272560026774 Signal peptide predicted for BPSS2160 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.788 between residues 20 and 21; signal peptide 272560026775 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560026776 trimer interface [polypeptide binding]; other site 272560026777 eyelet of channel; other site 272560026778 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -96.8, E-value 0.02 272560026779 Signal peptide predicted for BPSS2161 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.905 between residues 28 and 29; signal peptide 272560026780 Uncharacterized protein involved in propionate catabolism [General function prediction only]; Region: PrpD; COG2079 272560026781 Pfam match to entry PF03972 MmgE_PrpD, MmgE/PrpD family , score 388.5, E-value 4.3e-114 272560026782 OpgC protein; Region: OpgC_C; pfam10129 272560026783 10 probable transmembrane helices predicted for BPSS2162 by TMHMM2.0 at aa 95-117, 127-146, 167-189, 221-243, 248-266, 281-298, 305-327, 342-364, 376-395 and 410-432 272560026784 Predicted permeases [General function prediction only]; Region: RarD; COG2962 272560026785 10 probable transmembrane helices predicted for BPSS2163 by TMHMM2.0 at aa 13-35, 45-67, 80-102, 107-129, 136-153, 157-176, 183-205, 215-237, 244-266 and 271-293 272560026786 acylphosphatase; Provisional; Region: PRK14424 272560026787 Pfam match to entry PF00708 Acylphosphatase, Acylphosphatase , score 48.5, E-value 9.4e-12 272560026788 PS00151 Acylphosphatase signature 2. 272560026789 PS00150 Acylphosphatase signature 1. 272560026790 hopanoid-associated sugar epimerase; Region: HpnA; TIGR03466 272560026791 uncharacterized subgroup of aldehyde reductase and flavonoid reductase related proteins, extended (e) SDRs; Region: AR_FR_like_1_SDR_e; cd05228 272560026792 putative NADP binding site [chemical binding]; other site 272560026793 putative substrate binding site [chemical binding]; other site 272560026794 active site 272560026795 Pfam match to entry PF03406 Phage_fiber_2, Phage tail fiber repeat , score 3.5, E-value 8 272560026796 hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469 272560026797 Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535 272560026798 active site 272560026799 3 probable transmembrane helices predicted for BPSS2167 by TMHMM2.0 at aa 4-26, 301-323 and 353-375 272560026800 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 85.3, E-value 7.8e-23 272560026801 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944 272560026802 Fe-S cluster binding site [ion binding]; other site 272560026803 substrate binding site [chemical binding]; other site 272560026804 catalytic site [active] 272560026805 Pfam match to entry PF02401 LYTB, LytB protein , score 615.9, E-value 1.5e-182 272560026806 hopanoid biosynthesis associated radical SAM protein HpnH; Region: HpnH; TIGR03470 272560026807 Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335 272560026808 FeS/SAM binding site; other site 272560026809 Domain of unknown function (DUF3463); Region: DUF3463; pfam11946 272560026810 Pfam match to entry PF01444 MoaA_NifB_PqqE, moaA / nifB / pqqE family , score 54.8, E-value 1.2e-13 272560026811 Dopa 4,5-dioxygenase family; Region: DOPA_dioxygen; pfam08883 272560026812 aminotransferase; Validated; Region: PRK07046 272560026813 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001 272560026814 pyridoxal 5'-phosphate binding pocket [chemical binding]; other site 272560026815 catalytic residue [active] 272560026816 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 38.5, E-value 2e-17 272560026817 Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093 272560026818 sequence-specific DNA binding site [nucleotide binding]; other site 272560026819 salt bridge; other site 272560026820 Protein of unknown function (DUF466); Region: DUF466; pfam04328 272560026821 carbon starvation protein A; Provisional; Region: PRK15015 272560026822 Signal peptide predicted for BPSS2173 by SignalP 2.0 HMM (Signal peptide probability 0.998) with cleavage site probability 0.918 between residues 27 and 28; signal peptide 272560026823 Carbon starvation protein CstA; Region: CstA; pfam02554 272560026824 C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722 272560026825 16 probable transmembrane helices predicted for BPSS2173 by TMHMM2.0 at aa 5-27, 32-49, 86-108, 118-140, 161-183, 187-209, 221-239, 254-276, 283-305, 320-342, 363-385, 463-482, 509-528, 543-565, 572-594 and 642-664 272560026826 Pfam match to entry PF02554 CstA, Carbon starvation protein CstA , score 854.2, E-value 2.9e-254 272560026827 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596 272560026828 Putative lysophospholipase; Region: Hydrolase_4; cl19140 272560026829 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 37.5, E-value 1.9e-08 272560026830 Uncharacterized conserved protein [Function unknown]; Region: COG5476 272560026831 Protein of unknown function (DUF1485); Region: DUF1485; pfam07364 272560026832 MlrC C-terminus; Region: MlrC_C; pfam07171 272560026833 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560026834 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026835 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560026836 dimerization interface [polypeptide binding]; other site 272560026837 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 76.2, E-value 4.4e-20 272560026838 Predicted helix-turn-helix motif with score 1555.000, SD 4.48 at aa 27-48, sequence GTIRGAADHINTSPSVITRQIR 272560026839 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026840 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 129.9, E-value 3e-36 272560026841 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026842 ChaP, an enzyme involved in the biosynthesis of the antitumor agent chartreusin (cha); and similar proteins; Region: ChaP_like; cd08351 272560026843 metal binding site [ion binding]; metal-binding site 272560026844 Pfam match to entry PF00903 Glyoxalase, Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily , score 30.5, E-value 2.6e-06 272560026845 PS00082 Extradiol ring-cleavage dioxygenases signature. 272560026846 SnoaL-like domain; Region: SnoaL_2; pfam12680 272560026847 GtrA-like protein; Region: GtrA; pfam04138 272560026848 4 probable transmembrane helices predicted for BPSS2180 by TMHMM2.0 at aa 13-35, 45-67, 79-101 and 105-127 272560026849 S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440 272560026850 S-adenosylmethionine binding site [chemical binding]; other site 272560026851 undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714 272560026852 Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187 272560026853 Ligand binding site; other site 272560026854 Putative Catalytic site; other site 272560026855 DXD motif; other site 272560026856 2 probable transmembrane helices predicted for BPSS2182 by TMHMM2.0 at aa 256-278 and 288-310 272560026857 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 102.6, E-value 5e-28 272560026858 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 272560026859 PS00294 Prenyl group binding site (CAAX box). 272560026860 8 probable transmembrane helices predicted for BPSS2183 by TMHMM2.0 at aa 37-59, 131-153, 166-188, 203-225, 238-260, 296-318, 331-353 and 390-412 272560026861 Protein of unknown function (DUF2029); Region: DUF2029; pfam09594 272560026862 10 probable transmembrane helices predicted for BPSS2184 by TMHMM2.0 at aa 24-46, 61-80, 101-120, 125-147, 159-181, 196-218, 230-252, 291-313, 341-363 and 383-402 272560026863 Flp/Fap pilin component; Region: Flp_Fap; cl01585 272560026864 1 probable transmembrane helix predicted for BPSS2185 by TMHMM2.0 at aa 20-42 272560026865 Flp/Fap pilin component; Region: Flp_Fap; pfam04964 272560026866 1 probable transmembrane helix predicted for BPSS2186 by TMHMM2.0 at aa 35-57 272560026867 Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960 272560026868 5 probable transmembrane helices predicted for BPSS2187 by TMHMM2.0 at aa 5-24, 31-50, 55-77, 98-120 and 156-178 272560026869 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944 272560026870 Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190 272560026871 active site 272560026872 Protein Kinases, catalytic domain; Region: PKc_like; cl09925 272560026873 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026874 Signal peptide predicted for BPSS2189 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.474 between residues 42 and 43; signal peptide 272560026875 SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614 272560026876 Pilus formation protein N terminal region; Region: T2SS-T3SS_pil_N; pfam13629 272560026877 Flp pilus assembly protein, secretin CpaC [Intracellular trafficking and secretion]; Region: CpaC; COG4964 272560026878 Bacterial type II and III secretion system protein; Region: Secretin; pfam00263 272560026879 1 probable transmembrane helix predicted for BPSS2190 by TMHMM2.0 at aa 20-39 272560026880 Pfam match to entry PF00263 GSPII_III, Bacterial type II and III secretion system protein , score 219.3, E-value 3.6e-63 272560026881 Signal peptide predicted for BPSS2191 by SignalP 2.0 HMM (Signal peptide probability 0.991) with cleavage site probability 0.916 between residues 27 and 28; signal peptide 272560026882 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560026883 Putative Flp pilus-assembly TadE/G-like; Region: Tad; pfam13400 272560026884 1 probable transmembrane helix predicted for BPSS2192 by TMHMM2.0 at aa 2-19 272560026885 PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 272560026886 Flp pilus assembly protein TadG [Intracellular trafficking and secretion]; Region: TadG; COG4961 272560026887 TadE-like protein; Region: TadE; pfam07811 272560026888 1 probable transmembrane helix predicted for BPSS2193 by TMHMM2.0 at aa 13-35 272560026889 TadE-like protein; Region: TadE; pfam07811 272560026890 1 probable transmembrane helix predicted for BPSS2194 by TMHMM2.0 at aa 20-42 272560026891 FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784 272560026892 Flp pilus assembly protein, ATPase CpaE [Intracellular trafficking and secretion]; Region: CpaE; COG4963 272560026893 This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains...; Region: CpaE_like; cd03111 272560026894 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score -0.8, E-value 0.00061 272560026895 PS00237 G-protein coupled receptors signature. 272560026896 Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130 272560026897 ATP binding site [chemical binding]; other site 272560026898 Walker A motif; other site 272560026899 hexamer interface [polypeptide binding]; other site 272560026900 Walker B motif; other site 272560026901 Pfam match to entry PF00437 GSPII_E, Type II/IV secretion system protein , score -43.2, E-value 2e-07 272560026902 PS00227 Tubulin subunits alpha, beta, and gamma signature. 272560026903 PS00017 ATP/GTP-binding site motif A (P-loop). 272560026904 Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965 272560026905 5 probable transmembrane helices predicted for BPSS2197 by TMHMM2.0 at aa 10-32, 99-121, 126-145, 271-290 and 305-322 272560026906 Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064 272560026907 4 probable transmembrane helices predicted for BPSS2198 by TMHMM2.0 at aa 10-32, 110-129, 133-155 and 284-306 272560026908 Transcriptional regulators [Transcription]; Region: Lrp; COG1522 272560026909 Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090 272560026910 putative DNA binding site [nucleotide binding]; other site 272560026911 putative Zn2+ binding site [ion binding]; other site 272560026912 AsnC family; Region: AsnC_trans_reg; pfam01037 272560026913 Pfam match to entry PF01037 ASNC_trans_reg, AsnC family , score 99.7, E-value 3.6e-27 272560026914 PS00519 Bacterial regulatory proteins, asnC family signature. 272560026915 Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155 272560026916 Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609 272560026917 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560026918 homodimer interface [polypeptide binding]; other site 272560026919 catalytic residue [active] 272560026920 Pfam match to entry PF00155 aminotran_1_2, Aminotransferase class I and II , score 293.4, E-value 1.9e-85 272560026921 PS00070 Aldehyde dehydrogenases cysteine active site. 272560026922 YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448 272560026923 homotrimer interaction site [polypeptide binding]; other site 272560026924 putative active site [active] 272560026925 Pfam match to entry PF01042 UPF0076, YjgF family , score 76.5, E-value 3.5e-20 272560026926 Signal peptide predicted for BPSS2202 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 23 and 24; signal peptide 272560026927 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560026928 trimer interface [polypeptide binding]; other site 272560026929 eyelet of channel; other site 272560026930 2 probable transmembrane helices predicted for BPSS2202 by TMHMM2.0 at aa 10-32 and 154-176 272560026931 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -56.9, E-value 0.00051 272560026932 Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113 272560026933 Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468 272560026934 Pfam match to entry PF00324 aa_permeases, Amino acid permease , score 435.6, E-value 2.9e-128 272560026935 12 probable transmembrane helices predicted for BPSS2203 by TMHMM2.0 at aa 28-50, 55-77, 98-120, 130-152, 161-183, 212-234, 254-276, 291-313, 344-366, 371-393, 413-435 and 439-461 272560026936 PS00218 Amino acid permeases signature. 272560026937 Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414 272560026938 DNA-binding site [nucleotide binding]; DNA binding site 272560026939 Transcriptional regulators [Transcription]; Region: FadR; COG2186 272560026940 FCD domain; Region: FCD; pfam07729 272560026941 Pfam match to entry PF00392 gntR, Bacterial regulatory proteins, gntR family , score 31.0, E-value 1.8e-06 272560026942 Uncharacterized conserved protein [Function unknown]; Region: COG5476 272560026943 Protein of unknown function (DUF1485); Region: DUF1485; pfam07364 272560026944 MlrC C-terminus; Region: MlrC_C; pfam07171 272560026945 PS00343 Gram-positive cocci surface proteins 'anchoring' hexapeptide. 272560026946 4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332 272560026947 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560026948 putative substrate translocation pore; other site 272560026949 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -80.0, E-value 5.1e-05 272560026950 12 probable transmembrane helices predicted for BPSS2206 by TMHMM2.0 at aa 21-43, 58-80, 87-107, 112-134, 147-169, 179-201, 248-270, 280-302, 315-333, 338-360, 373-395 and 400-422 272560026951 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560026952 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560026953 The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398 272560026954 dimerization interface [polypeptide binding]; other site 272560026955 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 82.9, E-value 4.3e-22 272560026956 Predicted helix-turn-helix motif with score 1767.000, SD 5.21 at aa 22-43, sequence GSIRAAAERLNTAPSVVSRQLQ 272560026957 PS00044 Bacterial regulatory proteins, lysR family signature. 272560026958 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 116.4, E-value 3.5e-32 272560026959 Protein of unknown function (DUF3175); Region: DUF3175; pfam11373 272560026960 Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454 272560026961 Pfam match to entry PF00999 Na_H_Exchanger, Sodium/hydrogen exchanger family , score 4.5, E-value 2.4e-06 272560026962 9 probable transmembrane helices predicted for BPSS2210 by TMHMM2.0 at aa 5-24, 31-50, 60-82, 95-117, 191-213, 234-256, 342-364, 376-395 and 410-432 272560026963 ATP-dependent DNA ligase; Reviewed; Region: ligD; PRK05972 272560026964 DNA polymerase Ligase (LigD); Region: LigD_N; cl11819 272560026965 Adenylation domain of Mycobacterium tuberculosis LigD and LigC-like ATP-dependent DNA ligases; Region: Adenylation_DNA_ligase_LigD_LigC; cd07906 272560026966 active site 272560026967 DNA binding site [nucleotide binding] 272560026968 The Oligonucleotide/oligosaccharide binding (OB)-fold domain of ATP-dependent DNA ligase LigD is a DNA-binding module that is part of the catalytic core unit; Region: OBF_DNA_ligase_LigD; cd07971 272560026969 DNA binding site [nucleotide binding] 272560026970 PaeLigD_Pol_like: Polymerase (Pol) domain of bacterial LigD proteins similar to Pseudomonas aeruginosa (Pae) LigD. The LigD Pol domain belongs to the archaeal/eukaryal primase (AEP) superfamily. In prokaryotes, LigD along with Ku is required for...; Region: PaeLigD_Pol_like; cd04862 272560026971 nucleotide binding site [chemical binding]; other site 272560026972 Pfam match to entry PF01068 DNA_ligase, ATP dependent DNA ligase domain , score 80.9, E-value 1.7e-21 272560026973 PS00697 ATP-dependent DNA ligase AMP-binding site. 272560026974 Ku-homolog [Replication, recombination, and repair]; Region: COG1273 272560026975 Ku-core domain, Ku-like subfamily; composed of prokaryotic homologs of the eukaryotic DNA binding protein Ku. The alignment includes the core domain shared by the prokaryotic YkoV-like proteins and the eukaryotic Ku70 and Ku80. The prokaryotic Ku...; Region: KU_like; cd00789 272560026976 putative DNA binding site [nucleotide binding]; other site 272560026977 putative homodimer interface [polypeptide binding]; other site 272560026978 Pfam match to entry PF02735 ku, Ku70/Ku80 beta-barrel domain , score 185.4, E-value 6.1e-53 272560026979 Predicted membrane protein [Function unknown]; Region: COG2323 272560026980 2 probable transmembrane helices predicted for BPSS2213 by TMHMM2.0 at aa 20-42 and 55-77 272560026981 hydroperoxidase II; Provisional; Region: katE; PRK11249 272560026982 Catalase-like heme-binding proteins and protein domains; Region: catalase_like; cl09506 272560026983 heme binding pocket [chemical binding]; other site 272560026984 Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132 272560026985 domain interactions; other site 272560026986 Pfam match to entry PF01965 DJ-1_PfpI, DJ-1/PfpI family , score 1.1, E-value 0.00064 272560026987 Pfam match to entry PF00199 catalase, Catalase , score 868.3, E-value 1.6e-258 272560026988 PS00437 Catalase proximal heme-ligand signature. 272560026989 PS00438 Catalase proximal active site signature. 272560026990 Protein of unknown function (DUF3022); Region: DUF3022; pfam11226 272560026991 hypothetical protein; Provisional; Region: PRK13682 272560026992 2 probable transmembrane helices predicted for BPSS2216 by TMHMM2.0 at aa 21-43 and 49-66 272560026993 Protein of unknwon function (DUF3008); Region: DUF3008; pfam11450 272560026994 RNA polymerase factor sigma-54; Provisional; Region: PRK12469 272560026995 Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963 272560026996 Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552 272560026997 Pfam match to entry PF00309 Sigma54_factors, Sigma-54 factors family , score 601.6, E-value 3.1e-178 272560026998 PS00718 Sigma-54 factors family signature 2. 272560026999 Predicted helix-turn-helix motif with score 2008.000, SD 6.03 at aa 378-399, sequence LVLRDIADELGLHESTISRATG 272560027000 PS00717 Sigma-54 factors family signature 1. 272560027001 Domain of unknown function (DUF4397); Region: DUF4397; pfam14344 272560027002 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560027003 Mn-containing catalase [Inorganic ion transport and metabolism]; Region: COG3546 272560027004 dinuclear metal binding motif [ion binding]; other site 272560027005 Domain of unknown function (DUF892); Region: DUF892; pfam05974 272560027006 Protein of unknown function (DUF3005); Region: DUF3005; pfam11448 272560027007 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027008 Signal peptide predicted for BPSS2223 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 28 and 29; signal peptide 272560027009 Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713 272560027010 PS01070 DNA/RNA non-specific endonucleases active site. 272560027011 Signal peptide predicted for BPSS2224 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.459 between residues 32 and 33; signal peptide 272560027012 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560027013 FOG: CBS domain [General function prediction only]; Region: COG0517 272560027014 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622 272560027015 Pfam match to entry PF00571 CBS, CBS domain , score 60.7, E-value 2.1e-15 272560027016 Pfam match to entry PF00571 CBS, CBS domain , score 38.5, E-value 9.8e-09 272560027017 PRC-barrel domain; Region: PRC; pfam05239 272560027018 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560027019 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027020 active site 272560027021 phosphorylation site [posttranslational modification] 272560027022 intermolecular recognition site; other site 272560027023 dimerization interface [polypeptide binding]; other site 272560027024 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 63.3, E-value 3.3e-16 272560027025 Signal peptide predicted for BPSS2232 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.764 between residues 22 and 23; signal peptide 272560027026 Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030 272560027027 Fe-S cluster binding site [ion binding]; other site 272560027028 active site 272560027029 Pfam match to entry PF03167 UDG, Uracil DNA glycosylase superfamily , score 77.2, E-value 2.1e-20 272560027030 Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914 272560027031 Natural resistance-associated macrophage protein; Region: Nramp; pfam01566 272560027032 Pfam match to entry PF01566 Nramp, Natural resistance-associated macrophage protein , score -213.5, E-value 2.6e-05 272560027033 10 probable transmembrane helices predicted for BPSS2234 by TMHMM2.0 at aa 123-145, 157-179, 194-216, 229-251, 266-285, 325-347, 373-395, 416-438, 443-465 and 478-500 272560027034 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027035 Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283 272560027036 Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063 272560027037 NAD binding site [chemical binding]; other site 272560027038 catalytic Zn binding site [ion binding]; other site 272560027039 structural Zn binding site [ion binding]; other site 272560027040 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 197.3, E-value 1.5e-56 272560027041 PS01098 Lipolytic enzymes G-D-S-L family, serine active site. 272560027042 Signal peptide predicted for BPSS2237 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.998 between residues 23 and 24; signal peptide 272560027043 Domain of unknown function (DUF4142); Region: DUF4142; pfam13628 272560027044 oxidoreductase; Provisional; Region: PRK06128 272560027045 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560027046 NAD(P) binding site [chemical binding]; other site 272560027047 active site 272560027048 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 275.5, E-value 4.6e-80 272560027049 PS00061 Short-chain dehydrogenases/reductases family signature. 272560027050 2 probable transmembrane helices predicted for BPSS2239 by TMHMM2.0 at aa 112-134 and 138-157 272560027051 Protein of unknown function (DUF2795); Region: DUF2795; pfam11387 272560027052 short chain dehydrogenase; Provisional; Region: PRK07109 272560027053 1 probable transmembrane helix predicted for BPSS2241 by TMHMM2.0 at aa 44-61 272560027054 Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300 272560027055 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560027056 NAD(P) binding site [chemical binding]; other site 272560027057 active site 272560027058 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 185.6, E-value 5.3e-53 272560027059 PS00061 Short-chain dehydrogenases/reductases family signature. 272560027060 Signal peptide predicted for BPSS2243 by SignalP 2.0 HMM (Signal peptide probability 0.992) with cleavage site probability 0.721 between residues 62 and 63; signal peptide 272560027061 BON domain; Region: BON; pfam04972 272560027062 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560027063 This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800 272560027064 D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449 272560027065 putative ADP-binding pocket [chemical binding]; other site 272560027066 PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1. 272560027067 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 163.3, E-value 2.7e-46 272560027068 Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451 272560027069 UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230 272560027070 NAD binding site [chemical binding]; other site 272560027071 putative substrate binding site 2 [chemical binding]; other site 272560027072 putative substrate binding site 1 [chemical binding]; other site 272560027073 active site 272560027074 Pfam match to entry PF01370 Epimerase, NAD dependent epimerase/dehydratase , score 127.3, E-value 1.8e-35 272560027075 Signal peptide predicted for BPSS2246 by SignalP 2.0 HMM (Signal peptide probability 0.725) with cleavage site probability 0.334 between residues 28 and 29; signal peptide 272560027076 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560027077 PAS domain; Region: PAS_9; pfam13426 272560027078 putative active site [active] 272560027079 heme pocket [chemical binding]; other site 272560027080 phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966 272560027081 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560027082 putative active site [active] 272560027083 heme pocket [chemical binding]; other site 272560027084 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560027085 dimer interface [polypeptide binding]; other site 272560027086 phosphorylation site [posttranslational modification] 272560027087 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560027088 ATP binding site [chemical binding]; other site 272560027089 Mg2+ binding site [ion binding]; other site 272560027090 G-X-G motif; other site 272560027091 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745 272560027092 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027093 active site 272560027094 phosphorylation site [posttranslational modification] 272560027095 intermolecular recognition site; other site 272560027096 dimerization interface [polypeptide binding]; other site 272560027097 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 76.1, E-value 4.9e-20 272560027098 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 153.5, E-value 2.4e-43 272560027099 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 77.6, E-value 1.7e-20 272560027100 Pfam match to entry PF00785 PAC, PAC motif , score 14.4, E-value 0.078 272560027101 Pfam match to entry PF00989 PAS, PAS domain , score 29.5, E-value 4.9e-06 272560027102 Pfam match to entry PF00785 PAC, PAC motif , score 10.7, E-value 0.21 272560027103 Pfam match to entry PF00989 PAS, PAS domain , score 21.0, E-value 2.2e-05 272560027104 3 probable transmembrane helices predicted for BPSS2246 by TMHMM2.0 at aa 13-35, 50-72 and 92-109 272560027105 GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929 272560027106 Predicted glycosyltransferases [General function prediction only]; Region: COG1216 272560027107 Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186 272560027108 Probable Catalytic site; other site 272560027109 metal-binding site 272560027110 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 96.6, E-value 3.1e-26 272560027111 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204 272560027112 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027113 active site 272560027114 phosphorylation site [posttranslational modification] 272560027115 intermolecular recognition site; other site 272560027116 dimerization interface [polypeptide binding]; other site 272560027117 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560027118 Walker A motif; other site 272560027119 ATP binding site [chemical binding]; other site 272560027120 Walker B motif; other site 272560027121 arginine finger; other site 272560027122 Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954 272560027123 Pfam match to entry PF02954 HTH_8, Bacterial regulatory protein, Fis family , score 50.2, E-value 3e-12 272560027124 Predicted helix-turn-helix motif with score 1185.000, SD 3.22 at aa 434-455, sequence GVKTHAAEVLDISLKTIYNRLA 272560027125 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560027126 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 434.5, E-value 6.1e-128 272560027127 PS00676 Sigma-54 interaction domain ATP-binding region B signature. 272560027128 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 92.4, E-value 5.8e-25 272560027129 The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009 272560027130 psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974 272560027131 Walker A motif; other site 272560027132 ATP binding site [chemical binding]; other site 272560027133 Walker B motif; other site 272560027134 arginine finger; other site 272560027135 Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420 272560027136 Pfam match to entry PF00158 Sigma54_activat, Sigma-54 interaction domain , score 406.3, E-value 1.9e-119 272560027137 PS00675 Sigma-54 interaction domain ATP-binding region A signature. 272560027138 PS00688 Sigma-54 interaction domain C-terminal part signature. 272560027139 Predicted helix-turn-helix motif with score 1145.000, SD 3.09 at aa 289-310, sequence GDKPRTAKALGISLKTLYNRLA 272560027140 Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438 272560027141 Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013 272560027142 Pfam match to entry PF00534 Glycos_transf_1, Glycosyl transferases group 1 , score 1.4, E-value 5e-05 272560027143 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560027144 putative active site [active] 272560027145 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 82.7, E-value 5.1e-22 272560027146 Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641 272560027147 Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394 272560027148 active site 272560027149 1 probable transmembrane helix predicted for BPSS2253 by TMHMM2.0 at aa 250-272 272560027150 Pfam match to entry PF00535 Glycos_transf_2, Glycosyl transferase , score 87.0, E-value 2.5e-23 272560027151 BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271 272560027152 Pfam match to entry PF02543 CmcH_NodU, Carbamoyltransferase , score 374.1, E-value 9.4e-110 272560027153 Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789 272560027154 putative active site [active] 272560027155 Pfam match to entry PF01075 Glyco_transf_9, Glycosyltransferase 9 (heptosyltransferase) , score 17.7, E-value 8.5e-08 272560027156 D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213 272560027157 Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427 272560027158 active site 272560027159 motif I; other site 272560027160 motif II; other site 272560027161 Pfam match to entry PF00702 Hydrolase, haloacid dehalogenase-like hydrolase , score 26.1, E-value 4.3e-05 272560027162 3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653 272560027163 classical (c) SDRs; Region: SDR_c; cd05233 272560027164 NAD(P) binding site [chemical binding]; other site 272560027165 active site 272560027166 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 221.5, E-value 8e-64 272560027167 ABC transporter transmembrane region; Region: ABC_membrane; pfam00664 272560027168 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265 272560027169 ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201 272560027170 Walker A/P-loop; other site 272560027171 ATP binding site [chemical binding]; other site 272560027172 Q-loop/lid; other site 272560027173 ABC transporter signature motif; other site 272560027174 Walker B; other site 272560027175 D-loop; other site 272560027176 H-loop/switch region; other site 272560027177 Histidine kinase-like ATPases; Region: HATPase_c; smart00387 272560027178 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027179 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560027180 active site 272560027181 phosphorylation site [posttranslational modification] 272560027182 intermolecular recognition site; other site 272560027183 dimerization interface [polypeptide binding]; other site 272560027184 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 63.1, E-value 3.8e-16 272560027185 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 15.2, E-value 0.00092 272560027186 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 228.5, E-value 6.1e-66 272560027187 PS00211 ABC transporters family signature. 272560027188 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027189 Pfam match to entry PF00664 ABC_membrane, ABC transporter transmembrane region , score 110.7, E-value 1.8e-30 272560027190 5 probable transmembrane helices predicted for BPSS2259 by TMHMM2.0 at aa 39-61, 71-93, 152-174, 179-201 and 290-312 272560027191 BON domain; Region: BON; pfam04972 272560027192 Phophatidylserine decarboxylase; Region: PSDC; pfam12588 272560027193 Phosphatidylserine decarboxylase; Region: PS_Dcarbxylase; pfam02666 272560027194 Pfam match to entry PF02666 PS_Dcarbxylase, Phosphatidylserine decarboxylase , score 37.8, E-value 3.4e-11 272560027195 succinate dehydrogenase iron-sulfur subunit; Provisional; Region: PRK12575 272560027196 2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085 272560027197 4Fe-4S dicluster domain; Region: Fer4_17; pfam13534 272560027198 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560027199 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084 272560027200 NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446 272560027201 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833 272560027202 Pfam match to entry PF03446 NAD_binding_2, NAD binding domain of 6-phosphogluconate dehydrogenase , score -49.4, E-value 5.5e-06 272560027203 PS00895 3-hydroxyisobutyrate dehydrogenase signature. 272560027204 nitrilotriacetate monoxygenase oxidizes nitrilotriacetate utilizing reduced flavin mononucleotide (FMNH2) and oxygen. The FMNH2 is provided by an NADH:flavin mononucleotide (FMN) oxidorductase that uses NADH to reduce FMN to FMNH2; Region: Nitrilotriacetate_monoxgenase; cd01095 272560027205 active site 272560027206 non-prolyl cis peptide bond; other site 272560027207 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 272560027208 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 272560027209 Pfam match to entry PF01648 ACPS, 4'-phosphopantetheinyl transferase superfamily , score 35.6, E-value 7.6e-08 272560027210 oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890 272560027211 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560027212 putative substrate translocation pore; other site 272560027213 12 probable transmembrane helices predicted for BPSS2267 by TMHMM2.0 at aa 13-35, 55-77, 84-106, 111-133, 146-168, 178-197, 228-250, 265-287, 294-311, 321-343, 350-372 and 382-404 272560027214 Flavin reductase like domain; Region: Flavin_Reduct; pfam01613 272560027215 Signal peptide predicted for BPSS2268 by SignalP 2.0 HMM (Signal peptide probability 0.911) with cleavage site probability 0.533 between residues 23 and 24; signal peptide 272560027216 Pfam match to entry PF01613 Flavin_Reduct, Flavin reductase like domain , score 99.2, E-value 5.3e-27 272560027217 Autoinducer binding domain; Region: Autoind_bind; pfam03472 272560027218 Predicted helix-turn-helix motif with score 1064.000, SD 2.81 at aa 333-354, sequence GGARHVAEELRLDERAVYQLFT 272560027219 dihydrolipoamide dehydrogenase; Validated; Region: PRK05976 272560027220 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560027221 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560027222 Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852 272560027223 Pfam match to entry PF02852 pyr_redox_dim, Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain , score 136.6, E-value 2.8e-38 272560027224 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 288.1, E-value 7.1e-84 272560027225 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027226 PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272560027227 branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856 272560027228 Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849 272560027229 E3 interaction surface; other site 272560027230 lipoyl attachment site [posttranslational modification]; other site 272560027231 e3 binding domain; Region: E3_binding; pfam02817 272560027232 2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198 272560027233 Pfam match to entry PF00198 2-oxoacid_dh, 2-oxo acid dehydrogenases acyltransferase (catalytic domain) , score 377.6, E-value 8e-111 272560027234 PS00038 Myc-type, 'helix-loop-helix' dimerization domain signature. 272560027235 Pfam match to entry PF02817 e3_binding, e3 binding domain , score 58.9, E-value 7.1e-15 272560027236 Pfam match to entry PF00364 biotin_lipoyl, Biotin-requiring enzyme , score 91.7, E-value 9.9e-25 272560027237 PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 272560027238 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022 272560027239 Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036 272560027240 alpha subunit interface [polypeptide binding]; other site 272560027241 TPP binding site [chemical binding]; other site 272560027242 heterodimer interface [polypeptide binding]; other site 272560027243 Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780 272560027244 Pfam match to entry PF02780 transketolase_C, Transketolase, C-terminal domain , score 195.4, E-value 5.9e-56 272560027245 Pfam match to entry PF02779 transket_pyr, Transketolase, pyridine binding domain , score 258.9, E-value 4.3e-75 272560027246 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal; Region: OxoDH_E1alpha_N; pfam12573 272560027247 Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000 272560027248 tetramer interface [polypeptide binding]; other site 272560027249 TPP-binding site [chemical binding]; other site 272560027250 heterodimer interface [polypeptide binding]; other site 272560027251 phosphorylation loop region [posttranslational modification] 272560027252 Pfam match to entry PF00676 E1_dehydrog, Dehydrogenase E1 component , score 464.6, E-value 5.3e-137 272560027253 Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins; Region: PYR_PYL_RCAR_like; cd07821 272560027254 putative hydrophobic ligand binding site [chemical binding]; other site 272560027255 protein interface [polypeptide binding]; other site 272560027256 gate; other site 272560027257 Fatty acid hydroxylase superfamily; Region: FA_hydroxylase; cl01132 272560027258 Polyketide cyclase / dehydrase and lipid transport; Region: Polyketide_cyc2; pfam10604 272560027259 hydrophobic ligand binding site; other site 272560027260 3 probable transmembrane helices predicted for BPSS2275 by TMHMM2.0 at aa 21-40, 50-69 and 111-133 272560027261 Transcriptional regulator [Transcription]; Region: LysR; COG0583 272560027262 Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126 272560027263 The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417 272560027264 substrate binding pocket [chemical binding]; other site 272560027265 dimerization interface [polypeptide binding]; other site 272560027266 Pfam match to entry PF00126 HTH_1, Bacterial regulatory helix-turn-helix protein, lysR family , score 90.9, E-value 1.7e-24 272560027267 Predicted helix-turn-helix motif with score 1685.000, SD 4.93 at aa 23-44, sequence QNLSRAAIRLHMSQPAVSNALT 272560027268 PS00044 Bacterial regulatory proteins, lysR family signature. 272560027269 Pfam match to entry PF03466 LysR_substrate, LysR substrate binding domain , score 91.0, E-value 1.6e-24 272560027270 Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303 272560027271 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450 272560027272 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560027273 GMC oxidoreductase; Region: GMC_oxred_C; pfam05199 272560027274 Pfam match to entry PF00732 GMC_oxred, GMC oxidoreductase , score 26.6, E-value 3.3e-08 272560027275 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 12.1, E-value 0.0022 272560027276 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992 272560027277 Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070 272560027278 Reductase C-terminal; Region: Reductase_C; pfam14759 272560027279 Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752 272560027280 Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209 272560027281 active site 272560027282 nucleophile elbow; other site 272560027283 Patatin phospholipase; Region: DUF3734; pfam12536 272560027284 Pfam match to entry PF01734 Patatin, Patatin-like phospholipase , score 74.7, E-value 1.3e-19 272560027285 PS00449 ATP synthase a subunit signature. 272560027286 Pfam match to entry PF00070 pyr_redox, Pyridine nucleotide-disulphide oxidoreductase , score 239.6, E-value 2.9e-69 272560027287 Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755 272560027288 Pfam match to entry PF01258 zf_dskA_traR, Prokaryotic dksA/traR C4-type zinc finger , score 31.2, E-value 1.5e-06 272560027289 PHB de-polymerase C-terminus; Region: PHB_depo_C; cl19415 272560027290 ribonucleotide reductase-like protein; Provisional; Region: PRK06948 272560027291 Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888 272560027292 active site 272560027293 dimer interface [polypeptide binding]; other site 272560027294 effector binding site; other site 272560027295 Pfam match to entry PF02867 ribonuc_red_lgC, Ribonucleotide reductase, barrel domain , score -77.2, E-value 1.5e-10 272560027296 Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270 272560027297 Phosphotransferase enzyme family; Region: APH; pfam01636 272560027298 AAA domain; Region: AAA_17; cl19128 272560027299 AAA domain; Region: AAA_33; pfam13671 272560027300 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027301 Nitroreductase family; Region: Nitroreductase; pfam00881 272560027302 FMN binding site [chemical binding]; other site 272560027303 dimer interface [polypeptide binding]; other site 272560027304 Nitroreductase family; Region: Nitroreductase; pfam00881 272560027305 Pfam match to entry PF00881 Nitroreductase, Nitroreductase , score 16.7, E-value 7.9e-05 272560027306 Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659 272560027307 Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792 272560027308 Sulfate transporter family; Region: Sulfate_transp; cl19250 272560027309 Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042 272560027310 11 probable transmembrane helices predicted for BPSS2285 by TMHMM2.0 at aa 44-66, 70-92, 97-119, 129-151, 164-186, 201-223, 228-250, 296-318, 369-388, 392-414 and 426-448 272560027311 Pfam match to entry PF00916 Sulfate_transp, Sulfate transporter family , score 175.5, E-value 5.8e-50 272560027312 Pfam match to entry PF01740 STAS, STAS domain , score 70.6, E-value 2.1e-18 272560027313 FOG: CBS domain [General function prediction only]; Region: COG0517 272560027314 The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622 272560027315 Pfam match to entry PF00571 CBS, CBS domain , score 56.5, E-value 3.8e-14 272560027316 Pfam match to entry PF00571 CBS, CBS domain , score 48.8, E-value 7.6e-12 272560027317 This family is the oxydase domain of NRPS (non-ribosomal peptide synthetase) and other proteins that modify polypeptides by cyclizing a thioester to form a ring. These include epoB, part of the epothilone biosynthesis pathway; tubD, part of the tubulysin...; Region: mcbC-like_oxidoreductase; cd02142 272560027318 putative FMN binding site [chemical binding]; other site 272560027319 NADPH bind site [chemical binding]; other site 272560027320 Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071 272560027321 Group of bacterial proteins containing an alpha crystallin domain (ACD) similar to Lactobacillus plantarum (Lp) small heat shock proteins (sHsp) HSP 18.5, HSP 18.55 and HSP 19.3. sHsps are molecular chaperones that suppress protein aggregation and...; Region: ACD_LpsHSP_like; cd06471 272560027322 putative dimer interface [polypeptide binding]; other site 272560027323 Pfam match to entry PF00011 HSP20, Hsp20/alpha crystallin family , score 95.1, E-value 8.8e-26 272560027324 Signal peptide predicted for BPSS2306 by SignalP 2.0 HMM (Signal peptide probability 0.970) with cleavage site probability 0.969 between residues 21 and 22; signal peptide 272560027325 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560027326 trimer interface [polypeptide binding]; other site 272560027327 eyelet of channel; other site 272560027328 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -112.2, E-value 0.081 272560027329 PS00211 ABC transporters family signature. 272560027330 PS00225 Crystallins beta and gamma 'Greek key' motif signature. 272560027331 long-chain-fatty-acid--CoA ligase; Validated; Region: PRK06187 272560027332 Adenylate forming domain, Class I; Region: AFD_class_I; cl17068 272560027333 acyl-activating enzyme (AAE) consensus motif; other site 272560027334 AMP binding site [chemical binding]; other site 272560027335 active site 272560027336 CoA binding site [chemical binding]; other site 272560027337 Pfam match to entry PF00501 AMP-binding, AMP-binding enzyme , score 300.3, E-value 1.6e-87 272560027338 3 probable transmembrane helices predicted for BPSS2290 by TMHMM2.0 at aa 56-78, 88-105 and 234-256 272560027339 PS00455 AMP-binding domain signature. 272560027340 ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909 272560027341 AAA domain; Region: AAA_22; pfam13401 272560027342 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560027343 DNA binding residues [nucleotide binding] 272560027344 dimerization interface [polypeptide binding]; other site 272560027345 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 64.3, E-value 1.7e-16 272560027346 Predicted helix-turn-helix motif with score 1506.000, SD 4.32 at aa 872-893, sequence LSNKEIALAMTVGEETVKWHLK 272560027347 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027348 Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814 272560027349 quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754 272560027350 Quinone oxidoreductase (QOR); Region: QOR2; cd05286 272560027351 NADP binding site [chemical binding]; other site 272560027352 dimer interface [polypeptide binding]; other site 272560027353 Pfam match to entry PF00107 adh_zinc, Zinc-binding dehydrogenase , score 254.8, E-value 7.6e-74 272560027354 PS01162 Quinone oxidoreductase / zeta-crystallin signature. 272560027355 PS00307 Legume lectins beta-chain signature. 272560027356 Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cl00184 272560027357 Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175 272560027358 Pfam match to entry PF02668 TauD, Taurine catabolism dioxygenase TauD, TfdA family , score 199.3, E-value 4e-57 272560027359 Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853 272560027360 benzoate transport; Region: 2A0115; TIGR00895 272560027361 The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174 272560027362 putative substrate translocation pore; other site 272560027363 12 probable transmembrane helices predicted for BPSS2296 by TMHMM2.0 at aa 21-40, 60-82, 94-116, 120-142, 149-171, 181-200, 239-261, 276-298, 310-332, 337-359, 371-393 and 397-419 272560027364 Pfam match to entry PF00083 sugar_tr, Sugar (and other) transporter , score -61.5, E-value 1.2e-05 272560027365 Predicted esterase of the alpha/beta hydrolase fold [General function prediction only]; Region: COG3545 272560027366 Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695 272560027367 DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins; Region: DsbA_FrnE; cd03024 272560027368 catalytic residues [active] 272560027369 Pfam match to entry PF00384 molybdopterin, Molybdopterin oxidoreductase , score 120.9, E-value 1.5e-33 272560027370 Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928 272560027371 Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243 272560027372 molybdopterin cofactor binding site; other site 272560027373 The MopB_CT_2 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is...; Region: MopB_CT_2; cd02783 272560027374 putative molybdopterin cofactor binding site; other site 272560027375 PS00215 Mitochondrial energy transfer proteins signature. 272560027376 Pfam match to entry PF01568 Molydop_binding, Molydopterin dinucleotide binding domain , score 65.9, E-value 5.6e-17 272560027377 Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437 272560027378 4Fe-4S dicluster domain; Region: Fer4_11; pfam13247 272560027379 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 9.1, E-value 0.0064 272560027380 PS00190 Cytochrome c family heme-binding site signature. 272560027381 Pfam match to entry PF00037 fer4, 4Fe-4S binding domain , score 38.3, E-value 1.1e-08 272560027382 PS00198 4Fe-4S ferredoxins, iron-sulfur binding region signature. 272560027383 DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519 272560027384 8 probable transmembrane helices predicted for BPSS2301 by TMHMM2.0 at aa 5-27, 42-64, 83-105, 115-137, 150-172, 176-198, 252-274 and 279-301 272560027385 Signal peptide predicted for BPSS2302 by SignalP 2.0 HMM (Signal peptide probability 0.937) with cleavage site probability 0.922 between residues 31 and 32; signal peptide 272560027386 Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918 272560027387 putative active site [active] 272560027388 putative metal binding site [ion binding]; other site 272560027389 Signal peptide predicted for BPSS2303 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.980 between residues 29 and 30; signal peptide 272560027390 Putative glycosyl hydrolase domain; Region: DUF4015; pfam13200 272560027391 Transglycosylase; Region: Transgly; pfam00912 272560027392 penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074 272560027393 Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760 272560027394 Pfam match to entry PF00905 Transpeptidase, Penicillin binding protein transpeptidase domain , score 86.3, E-value 4.1e-23 272560027395 Pfam match to entry PF00912 Transglycosyl, Transglycosylase , score 253.3, E-value 2.1e-73 272560027396 1 probable transmembrane helix predicted for BPSS2304 by TMHMM2.0 at aa 34-56 272560027397 Signal peptide predicted for BPSS2305 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.999 between residues 22 and 23; signal peptide 272560027398 Thioredoxin-like; Region: Thioredoxin_7; pfam13899 272560027399 Bacterial protein of unknown function (DUF885); Region: DUF885; cl19872 272560027400 Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215 272560027401 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560027402 Signal peptide predicted for BPSS2306 by SignalP 2.0 HMM (Signal peptide probability 0.970) with cleavage site probability 0.969 between residues 24 and 25; signal peptide 272560027403 Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342 272560027404 trimer interface [polypeptide binding]; other site 272560027405 eyelet of channel; other site 272560027406 Pfam match to entry PF00267 Gram-ve_porins, Gram-negative porin , score -44.0, E-value 0.00016 272560027407 Signal peptide predicted for BPSS2307 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.947 between residues 27 and 28; signal peptide 272560027408 amidase; Provisional; Region: PRK08137 272560027409 Pfam match to entry PF01425 Amidase, Amidase , score 363.0, E-value 2e-106 272560027410 Signal peptide predicted for BPSS2308 by SignalP 2.0 HMM (Signal peptide probability 0.997) with cleavage site probability 0.678 between residues 26 and 27; signal peptide 272560027411 1 probable transmembrane helix predicted for BPSS2308 by TMHMM2.0 at aa 7-29 272560027412 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560027413 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560027414 Coenzyme A binding pocket [chemical binding]; other site 272560027415 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 83.9, E-value 2.1e-22 272560027416 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301 272560027417 Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670 272560027418 Coenzyme A binding pocket [chemical binding]; other site 272560027419 N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182 272560027420 Pfam match to entry PF00583 Acetyltransf, Acetyltransferase (GNAT) family , score 57.2, E-value 2.3e-14 272560027421 Putative modulator of DNA gyrase; Region: PmbA_TldD; cl19356 272560027422 Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312 272560027423 Pfam match to entry PF01523 PmbA_TldD, modulator of DNA gyrase , score 118.6, E-value 7.4e-33 272560027424 Probable gene remnant. Similar to C-terminal region of Ralstonia solanacearum probable ATP-binding ABC transporter protein rsc1176 or rs04549 SWALL:Q8Y068 (EMBL:AL646063) (551 aa) fasta scores: E(): 1.4e-13, 64.7% id in 85 aa, and to an internal region of Brucella abortus ABC transporter ATP-binding protein BaTn1953.ORF20 SWALL:Q8VQK7 (EMBL:AF454951) (334 aa) fasta scores: E(): 4e-10, 47.36% id in 114 aa. Similar to C-terminal regions BPSL2200, 51.064% identity (53.933% ungapped) in 94 aa overlap, and to BPSS2137, 51.579% identity (55.056% ungapped) in 95 aa overlap;probable ATP-binding ABC transporter protein (fragment) 272560027425 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4564 272560027426 Cache is an extracellular domain that is predicted to have a role in small-molecule recognition in a wide range of proteins; Region: Cache_2; smart01049 272560027427 Histidine kinase; Region: HisKA_3; pfam07730 272560027428 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560027429 ATP binding site [chemical binding]; other site 272560027430 Mg2+ binding site [ion binding]; other site 272560027431 G-X-G motif; other site 272560027432 2 probable transmembrane helices predicted for BPSS2314 by TMHMM2.0 at aa 7-26 and 207-229 272560027433 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 72.5, E-value 5.7e-19 272560027434 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197 272560027435 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027436 active site 272560027437 phosphorylation site [posttranslational modification] 272560027438 intermolecular recognition site; other site 272560027439 dimerization interface [polypeptide binding]; other site 272560027440 C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170 272560027441 DNA binding residues [nucleotide binding] 272560027442 dimerization interface [polypeptide binding]; other site 272560027443 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 132.5, E-value 5.1e-37 272560027444 Pfam match to entry PF00196 GerE, Bacterial regulatory proteins, luxR family , score 65.5, E-value 7.5e-17 272560027445 Signal peptide predicted for BPSS2316 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.992 between residues 20 and 21; signal peptide 272560027446 Toluene tolerance, Ttg2; Region: Tol_Tol_Ttg2; pfam05494 272560027447 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C [Coenzyme metabolism]; Region: COG5424 272560027448 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560027449 PAS domain; Region: PAS_9; pfam13426 272560027450 putative active site [active] 272560027451 heme pocket [chemical binding]; other site 272560027452 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560027453 metal binding site [ion binding]; metal-binding site 272560027454 active site 272560027455 I-site; other site 272560027456 EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948 272560027457 Pfam match to entry PF00563 EAL, EAL domain , score 278.2, E-value 6.9e-81 272560027458 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 183.8, E-value 1.8e-52 272560027459 2 probable transmembrane helices predicted for BPSS2318 by TMHMM2.0 at aa 91-113 and 277-299 272560027460 Signal peptide predicted for BPSS2319 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.993 between residues 30 and 31; signal peptide 272560027461 Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold [General function prediction only]; Region: LipA; COG1075 272560027462 alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561 272560027463 Pfam match to entry PF00561 abhydrolase, alpha/beta hydrolase fold , score 81.9, E-value 8.3e-22 272560027464 PS00120 Lipases, serine active site. 272560027465 Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091 272560027466 4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648 272560027467 Pfam match to entry PF01648 ACPS, 4'-phosphopantetheinyl transferase superfamily , score 21.6, E-value 2.5e-06 272560027468 PS00216 Sugar transport proteins signature 1. 272560027469 Domain of unknown function (DUF4345); Region: DUF4345; pfam14248 272560027470 4 probable transmembrane helices predicted for BPSS2321 by TMHMM2.0 at aa 7-29, 49-68, 75-97 and 101-123 272560027471 Signal peptide predicted for BPSS2322 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.380 between residues 22 and 23; signal peptide 272560027472 Signal peptide predicted for BPSS2323 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.983 between residues 22 and 23; signal peptide 272560027473 Outer membrane lipoprotein carrier protein LolA; Region: LolA; cl19192 272560027474 ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591 272560027475 FtsX-like permease family; Region: FtsX; pfam02687 272560027476 Pfam match to entry PF02687 DUF214, Predicted permease , score 98.5, E-value 8.5e-27 272560027477 4 probable transmembrane helices predicted for BPSS2324 by TMHMM2.0 at aa 21-38, 334-356, 390-412 and 438-460 272560027478 ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136 272560027479 ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255 272560027480 Walker A/P-loop; other site 272560027481 ATP binding site [chemical binding]; other site 272560027482 Q-loop/lid; other site 272560027483 ABC transporter signature motif; other site 272560027484 Walker B; other site 272560027485 D-loop; other site 272560027486 H-loop/switch region; other site 272560027487 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 169.4, E-value 3.8e-48 272560027488 PS00211 ABC transporters family signature. 272560027489 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027490 Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism]; Region: TrkA; COG2072 272560027491 NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134 272560027492 Pfam match to entry PF00743 FMO-like, Flavin-binding monooxygenase-like , score -34.3, E-value 1.1e-21 272560027493 Cytochrome P450; Region: p450; pfam00067 272560027494 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560027495 short chain dehydrogenase; Region: adh_short; pfam00106 272560027496 NAD(P) binding site [chemical binding]; other site 272560027497 active site 272560027498 Pfam match to entry PF00067 p450, Cytochrome P450 , score 257.4, E-value 1.3e-74 272560027499 PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 272560027500 PS00059 Zinc-containing alcohol dehydrogenases signature. 272560027501 enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08063 272560027502 1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359 272560027503 putative NAD(P) binding site [chemical binding]; other site 272560027504 active site 272560027505 polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833 272560027506 Beta-ketoacyl synthase; Region: PKS_KS; smart00825 272560027507 active site 272560027508 Beta-ketoacyl synthase, N-terminal domain; Region: ketoacyl-synt; pfam00109 272560027509 Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931 272560027510 NAD(P) binding site [chemical binding]; other site 272560027511 active site 272560027512 Polyketide synthase dehydratase; Region: PS-DH; pfam14765 272560027513 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 8.8, E-value 4.4e-08 272560027514 Pfam match to entry PF02801 ketoacyl-synt_C, Beta-ketoacyl synthase, C-terminal domain , score 207.0, E-value 1.8e-59 272560027515 Pfam match to entry PF00109 ketoacyl-synt, Beta-ketoacyl synthase, N-terminal domain , score 60.3, E-value 2.7e-15 272560027516 Pfam match to entry PF00106 adh_short, short chain dehydrogenase , score 212.5, E-value 4.1e-61 272560027517 Acyl transferase domain; Region: Acyl_transf_1; cl08282 272560027518 Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236 272560027519 Pfam match to entry PF00698 Acyl_transf, Acyl transferase domain , score 72.0, E-value 8.2e-19 272560027520 hopanoid biosynthesis associated RND transporter like protein HpnN; Region: HpnN; TIGR03480 272560027521 MMPL family; Region: MMPL; cl14618 272560027522 MMPL family; Region: MMPL; cl14618 272560027523 12 probable transmembrane helices predicted for BPSS2330 by TMHMM2.0 at aa 17-39, 277-296, 303-325, 329-351, 367-389, 404-426, 456-475, 715-737, 749-768, 772-794, 807-829 and 839-861 272560027524 VacJ like lipoprotein; Region: VacJ; cl01073 272560027525 Signal peptide predicted for BPSS2331 by SignalP 2.0 HMM (Signal peptide probability 0.999) with cleavage site probability 0.473 between residues 22 and 23; signal peptide 272560027526 PS00013 Prokaryotic membrane lipoprotein lipid attachment site. 272560027527 1 probable transmembrane helix predicted for BPSS2332 by TMHMM2.0 at aa 146-168 272560027528 Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610 272560027529 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161 272560027530 inhibitor-cofactor binding pocket; inhibition site 272560027531 pyridoxal 5'-phosphate binding site [chemical binding]; other site 272560027532 catalytic residue [active] 272560027533 Pfam match to entry PF00202 aminotran_3, Aminotransferase class-III , score 376.7, E-value 1.6e-110 272560027534 PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 272560027535 PS00196 Type-1 copper (blue) proteins signature. 272560027536 The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid. N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467 272560027537 glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493 272560027538 ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262 272560027539 Walker A/P-loop; other site 272560027540 ATP binding site [chemical binding]; other site 272560027541 Q-loop/lid; other site 272560027542 ABC transporter signature motif; other site 272560027543 Walker B; other site 272560027544 D-loop; other site 272560027545 H-loop/switch region; other site 272560027546 Pfam match to entry PF00005 ABC_tran, ABC transporter , score 236.7, E-value 2.1e-68 272560027547 PS00211 ABC transporters family signature. 272560027548 PS00017 ATP/GTP-binding site motif A (P-loop). 272560027549 glutamine ABC transporter permease protein; Reviewed; Region: glnP; PRK09494 272560027550 Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261 272560027551 dimer interface [polypeptide binding]; other site 272560027552 conserved gate region; other site 272560027553 putative PBP binding loops; other site 272560027554 ABC-ATPase subunit interface; other site 272560027555 4 probable transmembrane helices predicted for BPSS2336 by TMHMM2.0 at aa 42-64, 79-101, 108-130 and 206-228 272560027556 Pfam match to entry PF00528 BPD_transp, Binding-protein-dependent transport systems inner membrane component , score 60.6, E-value 2.2e-15 272560027557 Signal peptide predicted for BPSS2337 by SignalP 2.0 HMM (Signal peptide probability 1.000) with cleavage site probability 0.995 between residues 25 and 26; signal peptide 272560027558 glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495 272560027559 Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134 272560027560 substrate binding pocket [chemical binding]; other site 272560027561 membrane-bound complex binding site; other site 272560027562 hinge residues; other site 272560027563 Pfam match to entry PF00497 SBP_bac_3, Bacterial extracellular solute-binding proteins, family 3 , score 276.8, E-value 1.8e-80 272560027564 PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 272560027565 hypothetical protein; Provisional; Region: PRK07077 272560027566 squalene-hopene cyclase; Region: hopene_cyclase; TIGR01507 272560027567 Squalene cyclase (SQCY) domain subgroup 1; found in class II terpene cyclases that have an alpha 6 - alpha 6 barrel fold. Squalene cyclase (SQCY) and 2,3-oxidosqualene cyclase (OSQCY) are integral membrane proteins that catalyze a cationic cyclization...; Region: SQCY_1; cd02892 272560027568 Active site cavity [active] 272560027569 catalytic acid [active] 272560027570 Pfam match to entry PF00432 prenyltrans, Prenyltransferase and squalene oxidase repeat , score 5.6, E-value 0.46 272560027571 Pfam match to entry PF00432 prenyltrans, Prenyltransferase and squalene oxidase repeat , score 41.5, E-value 1.2e-09 272560027572 Pfam match to entry PF00432 prenyltrans, Prenyltransferase and squalene oxidase repeat , score 41.5, E-value 1.2e-09 272560027573 PS01074 Terpene synthases signature. 272560027574 Pfam match to entry PF00432 prenyltrans, Prenyltransferase and squalene oxidase repeat , score 11.9, E-value 0.0069 272560027575 Pfam match to entry PF00432 prenyltrans, Prenyltransferase and squalene oxidase repeat , score 37.1, E-value 2.7e-08 272560027576 Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683 272560027577 active site lid residues [active] 272560027578 substrate binding pocket [chemical binding]; other site 272560027579 catalytic residues [active] 272560027580 substrate-Mg2+ binding site; other site 272560027581 aspartate-rich region 1; other site 272560027582 aspartate-rich region 2; other site 272560027583 Pfam match to entry PF00494 SQS_PSY, Squalene/phytoene synthase , score 107.2, E-value 2.1e-29 272560027584 PS01045 Squalene and phytoene synthases signature 2. 272560027585 Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697 272560027586 Probable pheophorbidase; Region: PLN02965; cl17657 272560027587 PS00120 Lipases, serine active site. 272560027588 PAS fold; Region: PAS_4; pfam08448 272560027589 PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130 272560027590 putative active site [active] 272560027591 heme pocket [chemical binding]; other site 272560027592 Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949 272560027593 metal binding site [ion binding]; metal-binding site 272560027594 active site 272560027595 I-site; other site 272560027596 Pfam match to entry PF00990 GGDEF, GGDEF domain , score 209.4, E-value 3.5e-60 272560027597 Pfam match to entry PF00989 PAS, PAS domain , score 17.2, E-value 0.00025 272560027598 Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776 272560027599 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027600 active site 272560027601 phosphorylation site [posttranslational modification] 272560027602 intermolecular recognition site; other site 272560027603 dimerization interface [polypeptide binding]; other site 272560027604 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 73.4, E-value 3.1e-19 272560027605 Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642 272560027606 Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082 272560027607 dimer interface [polypeptide binding]; other site 272560027608 phosphorylation site [posttranslational modification] 272560027609 Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075 272560027610 ATP binding site [chemical binding]; other site 272560027611 Mg2+ binding site [ion binding]; other site 272560027612 G-X-G motif; other site 272560027613 Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156 272560027614 active site 272560027615 phosphorylation site [posttranslational modification] 272560027616 intermolecular recognition site; other site 272560027617 dimerization interface [polypeptide binding]; other site 272560027618 2 probable transmembrane helices predicted for BPSS2345 by TMHMM2.0 at aa 4-26 and 288-310 272560027619 Pfam match to entry PF00512 HisKA, His Kinase A (phosphoacceptor) domain , score 23.0, E-value 0.00014 272560027620 Pfam match to entry PF02518 HATPase_c, Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase , score 103.3, E-value 3.1e-28 272560027621 Pfam match to entry PF00072 response_reg, Response regulator receiver domain , score 69.1, E-value 6.3e-18 272560027622 Predicted flavoprotein [General function prediction only]; Region: COG0431 272560027623 Pfam match to entry PF03358 FMN_red, NADPH-dependent FMN reductase , score 101.2, E-value 1.3e-27 272560027624 RNA polymerase sigma factor; Provisional; Region: PRK12545 272560027625 Sigma-70 region 2; Region: Sigma70_r2; pfam04542 272560027626 Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281 272560027627 DNA binding residues [nucleotide binding] 272560027628 Putative zinc-finger; Region: zf-HC2; pfam13490 272560027629 Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034 272560027630 catalytic residues [active] 272560027631 Pfam match to entry PF03960 ArsC, ArsC family , score 95.5, E-value 7.1e-26 272560027632 ParA-like protein; Provisional; Region: PHA02518 272560027633 ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042 272560027634 VirC1 protein; Region: VirC1; cl17401 272560027635 P-loop; other site 272560027636 Magnesium ion binding site [ion binding]; other site 272560027637 Pfam match to entry PF00991 ParA, ParA family ATPase , score 18.4, E-value 3.7e-05 272560027638 Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475 272560027639 ParB-like nuclease domain; Region: ParB; smart00470 272560027640 Pfam match to entry PF02195 ParBc, ParB-like nuclease domain , score 55.2, E-value 9.5e-14 272560027641 Predicted helix-turn-helix motif with score 1771.000, SD 5.22 at aa 206-227, sequence QSQKELAEHLGLDESTVAVALS 272560027642 Initiator Replication protein; Region: Rep_3; pfam01051