-- dump date   	20140619_020655
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
926550000001	chromosomal replication initiator protein DnaA; Region: DnaA; TIGR00362
926550000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550000003	Walker A motif; other site
926550000004	ATP binding site [chemical binding]; other site
926550000005	Walker B motif; other site
926550000006	arginine finger; other site
926550000007	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
926550000008	DnaA box-binding interface [nucleotide binding]; other site
926550000009	recombinase A; Provisional; Region: recA; PRK09354
926550000010	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
926550000011	hexamer interface [polypeptide binding]; other site
926550000012	Walker A motif; other site
926550000013	ATP binding site [chemical binding]; other site
926550000014	Walker B motif; other site
926550000015	phosphodiesterase; Provisional; Region: PRK12704
926550000016	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550000017	Zn2+ binding site [ion binding]; other site
926550000018	Mg2+ binding site [ion binding]; other site
926550000019	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
926550000020	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
926550000021	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
926550000022	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550000023	catalytic core [active]
926550000024	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550000025	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926550000026	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926550000027	protein binding site [polypeptide binding]; other site
926550000028	Uncharacterized conserved protein [Function unknown]; Region: COG2353
926550000029	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
926550000030	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550000031	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550000032	catalytic residue [active]
926550000033	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
926550000034	tandem repeat interface [polypeptide binding]; other site
926550000035	oligomer interface [polypeptide binding]; other site
926550000036	active site residues [active]
926550000037	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
926550000038	tandem repeat interface [polypeptide binding]; other site
926550000039	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
926550000040	oligomer interface [polypeptide binding]; other site
926550000041	active site residues [active]
926550000042	Alanine dehydrogenase [Amino acid transport and metabolism]; Region: Ald; COG0686
926550000043	Alanine dehydrogenase NAD-binding and catalytic domains; Region: L-AlaDH; cd05305
926550000044	hexamer interface [polypeptide binding]; other site
926550000045	ligand binding site [chemical binding]; other site
926550000046	putative active site [active]
926550000047	NAD(P) binding site [chemical binding]; other site
926550000048	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
926550000049	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
926550000050	dimer interface [polypeptide binding]; other site
926550000051	motif 1; other site
926550000052	active site
926550000053	motif 2; other site
926550000054	motif 3; other site
926550000055	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
926550000056	anticodon binding site; other site
926550000057	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550000058	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550000059	ligand binding site [chemical binding]; other site
926550000060	flexible hinge region; other site
926550000061	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550000062	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550000063	ligand binding site [chemical binding]; other site
926550000064	flexible hinge region; other site
926550000065	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550000066	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550000067	ligand binding site [chemical binding]; other site
926550000068	flexible hinge region; other site
926550000069	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550000070	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550000071	ligand binding site [chemical binding]; other site
926550000072	flexible hinge region; other site
926550000073	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550000074	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
926550000075	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550000076	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550000077	DNA binding residues [nucleotide binding]
926550000078	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
926550000079	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
926550000080	DNA binding site [nucleotide binding]
926550000081	catalytic residue [active]
926550000082	H2TH interface [polypeptide binding]; other site
926550000083	putative catalytic residues [active]
926550000084	turnover-facilitating residue; other site
926550000085	intercalation triad [nucleotide binding]; other site
926550000086	8OG recognition residue [nucleotide binding]; other site
926550000087	putative reading head residues; other site
926550000088	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
926550000089	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
926550000090	PspC domain; Region: PspC; pfam04024
926550000091	PspC domain; Region: PspC; pfam04024
926550000092	UV-endonuclease UvdE; Region: UvdE; cl10036
926550000093	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
926550000094	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550000095	inhibitor-cofactor binding pocket; inhibition site
926550000096	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550000097	catalytic residue [active]
926550000098	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
926550000099	xanthine dehydrogenase accessory protein XdhC; Region: xanthine_xdhC; TIGR02964
926550000100	XdhC Rossmann domain; Region: XdhC_C; pfam13478
926550000101	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
926550000102	Class I hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classI; cd00643
926550000103	tetramerization interface [polypeptide binding]; other site
926550000104	substrate binding pocket [chemical binding]; other site
926550000105	catalytic residues [active]
926550000106	inhibitor binding sites; inhibition site
926550000107	NADP(H) binding site [chemical binding]; other site
926550000108	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
926550000109	N- and C-terminal domain interface [polypeptide binding]; other site
926550000110	D-xylulose kinase; Region: XylB; TIGR01312
926550000111	active site
926550000112	MgATP binding site [chemical binding]; other site
926550000113	catalytic site [active]
926550000114	metal binding site [ion binding]; metal-binding site
926550000115	xylulose binding site [chemical binding]; other site
926550000116	homodimer interface [polypeptide binding]; other site
926550000117	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926550000118	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000119	dimer interface [polypeptide binding]; other site
926550000120	conserved gate region; other site
926550000121	putative PBP binding loops; other site
926550000122	ABC-ATPase subunit interface; other site
926550000123	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
926550000124	NMT1/THI5 like; Region: NMT1; pfam09084
926550000125	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926550000126	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926550000127	Walker A/P-loop; other site
926550000128	ATP binding site [chemical binding]; other site
926550000129	Q-loop/lid; other site
926550000130	ABC transporter signature motif; other site
926550000131	Walker B; other site
926550000132	D-loop; other site
926550000133	H-loop/switch region; other site
926550000134	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
926550000135	beta-galactosidase; Region: BGL; TIGR03356
926550000136	Sec-independent protein secretion pathway components [Intracellular trafficking and secretion]; Region: TatA; COG1826
926550000137	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
926550000138	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
926550000139	Walker A/P-loop; other site
926550000140	ATP binding site [chemical binding]; other site
926550000141	Q-loop/lid; other site
926550000142	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
926550000143	ABC transporter signature motif; other site
926550000144	Walker B; other site
926550000145	D-loop; other site
926550000146	H-loop/switch region; other site
926550000147	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926550000148	phosphoglucomutase; Validated; Region: PRK07564
926550000149	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
926550000150	active site
926550000151	substrate binding site [chemical binding]; other site
926550000152	metal binding site [ion binding]; metal-binding site
926550000153	butyryl-CoA:acetate CoA-transferase; Region: butyr_acet_CoA; TIGR03948
926550000154	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
926550000155	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
926550000156	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550000157	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
926550000158	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673
926550000159	nudix motif; other site
926550000160	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550000161	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550000162	NAD(P) binding site [chemical binding]; other site
926550000163	active site
926550000164	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
926550000165	classical (c) SDRs; Region: SDR_c; cd05233
926550000166	NAD(P) binding site [chemical binding]; other site
926550000167	active site
926550000168	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
926550000169	active site
926550000170	catalytic residues [active]
926550000171	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550000172	classical (c) SDRs; Region: SDR_c; cd05233
926550000173	NAD(P) binding site [chemical binding]; other site
926550000174	active site
926550000175	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
926550000176	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
926550000177	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
926550000178	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
926550000179	active site residue [active]
926550000180	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
926550000181	active site residue [active]
926550000182	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550000183	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926550000184	Molybdopterin converting factor, small subunit [Coenzyme metabolism]; Region: MoaD; COG1977
926550000185	charged pocket; other site
926550000186	hydrophobic patch; other site
926550000187	molybdopterin biosynthesis protein MoeB; Validated; Region: PRK08762
926550000188	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550000189	active site residue [active]
926550000190	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
926550000191	ATP binding site [chemical binding]; other site
926550000192	substrate interface [chemical binding]; other site
926550000193	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
926550000194	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
926550000195	dimer interface [polypeptide binding]; other site
926550000196	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550000197	catalytic residue [active]
926550000198	Domain of unknown function (DUF4395); Region: DUF4395; pfam14340
926550000199	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550000200	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550000201	catalytic residues [active]
926550000202	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
926550000203	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
926550000204	active site
926550000205	putative substrate binding pocket [chemical binding]; other site
926550000206	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550000207	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550000208	MG2 domain; Region: A2M_N; pfam01835
926550000209	Alpha-2-macroglobulin family; Region: A2M; pfam00207
926550000210	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
926550000211	surface patch; other site
926550000212	thioester region; other site
926550000213	specificity defining residues; other site
926550000214	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000215	PAS domain; Region: PAS_9; pfam13426
926550000216	putative active site [active]
926550000217	heme pocket [chemical binding]; other site
926550000218	PAS domain S-box; Region: sensory_box; TIGR00229
926550000219	PAS domain S-box; Region: sensory_box; TIGR00229
926550000220	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000221	putative active site [active]
926550000222	heme pocket [chemical binding]; other site
926550000223	PAS fold; Region: PAS_3; pfam08447
926550000224	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000225	putative active site [active]
926550000226	heme pocket [chemical binding]; other site
926550000227	PAS fold; Region: PAS_4; pfam08448
926550000228	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000229	putative active site [active]
926550000230	heme pocket [chemical binding]; other site
926550000231	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550000232	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550000233	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550000234	dimer interface [polypeptide binding]; other site
926550000235	phosphorylation site [posttranslational modification]
926550000236	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550000237	ATP binding site [chemical binding]; other site
926550000238	Mg2+ binding site [ion binding]; other site
926550000239	G-X-G motif; other site
926550000240	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550000241	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000242	active site
926550000243	phosphorylation site [posttranslational modification]
926550000244	intermolecular recognition site; other site
926550000245	dimerization interface [polypeptide binding]; other site
926550000246	Response regulator receiver domain; Region: Response_reg; pfam00072
926550000247	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000248	active site
926550000249	phosphorylation site [posttranslational modification]
926550000250	intermolecular recognition site; other site
926550000251	dimerization interface [polypeptide binding]; other site
926550000252	Protein of unknown function (DUF981); Region: DUF981; pfam06168
926550000253	N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Provisional; Region: PRK02264
926550000254	Methenyltetrahydromethanopterin (methenyl-H4MPT) cyclohydrolase (MCH). MCH is a cytoplasmic enzyme that has been identified in methanogenic archaea, sulfate- reducing archaea, and methylotrophic bacteria.  It catalyzes the reversible formation of N(5), N...; Region: MCH; cl00249
926550000255	trimer interface I [polypeptide binding]; other site
926550000256	putative substrate binding pocket [chemical binding]; other site
926550000257	trimer interface II [polypeptide binding]; other site
926550000258	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
926550000259	classical (c) SDRs; Region: SDR_c; cd05233
926550000260	NAD(P) binding site [chemical binding]; other site
926550000261	active site
926550000262	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550000263	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550000264	E3 interaction surface; other site
926550000265	lipoyl attachment site [posttranslational modification]; other site
926550000266	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550000267	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926550000268	alpha subunit interface [polypeptide binding]; other site
926550000269	TPP binding site [chemical binding]; other site
926550000270	heterodimer interface [polypeptide binding]; other site
926550000271	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550000272	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926550000273	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550000274	tetramer interface [polypeptide binding]; other site
926550000275	TPP-binding site [chemical binding]; other site
926550000276	heterodimer interface [polypeptide binding]; other site
926550000277	phosphorylation loop region [posttranslational modification]
926550000278	putative hypoxanthine oxidase; Provisional; Region: PRK09800
926550000279	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550000280	catalytic loop [active]
926550000281	iron binding site [ion binding]; other site
926550000282	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926550000283	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926550000284	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926550000285	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
926550000286	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; cl08390
926550000287	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
926550000288	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926550000289	non-specific DNA binding site [nucleotide binding]; other site
926550000290	salt bridge; other site
926550000291	sequence-specific DNA binding site [nucleotide binding]; other site
926550000292	Protease II [Amino acid transport and metabolism]; Region: PtrB; COG1770
926550000293	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926550000294	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
926550000295	Domain of unknown function DUF21; Region: DUF21; pfam01595
926550000296	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926550000297	Transporter associated domain; Region: CorC_HlyC; smart01091
926550000298	hypothetical protein; Provisional; Region: PRK06815
926550000299	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926550000300	tetramer interface [polypeptide binding]; other site
926550000301	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550000302	catalytic residue [active]
926550000303	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926550000304	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550000305	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550000306	S-adenosylmethionine binding site [chemical binding]; other site
926550000307	Methyltransferase domain; Region: Methyltransf_11; pfam08241
926550000308	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550000309	exopolyphosphatase; Region: exo_poly_only; TIGR03706
926550000310	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
926550000311	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
926550000312	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550000313	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550000314	DNA binding residues [nucleotide binding]
926550000315	CHAT domain; Region: CHAT; pfam12770
926550000316	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550000317	active site
926550000318	catalytic residues [active]
926550000319	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
926550000320	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
926550000321	Domain of Unknown Function (DUF1080); Region: DUF1080; pfam06439
926550000322	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
926550000323	fimbrial isopeptide formation D2 domain; Region: RrgB_K2N_iso_D2; TIGR04226
926550000324	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000325	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000326	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000327	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000328	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000329	Domain of unknown function DUF11; Region: DUF11; cl17728
926550000330	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000331	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550000332	Domain of unknown function DUF11; Region: DUF11; cl17728
926550000333	Domain of unknown function DUF11; Region: DUF11; cl17728
926550000334	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926550000335	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550000336	catalytic residues [active]
926550000337	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
926550000338	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
926550000339	Walker A/P-loop; other site
926550000340	ATP binding site [chemical binding]; other site
926550000341	Q-loop/lid; other site
926550000342	ABC transporter signature motif; other site
926550000343	Walker B; other site
926550000344	D-loop; other site
926550000345	H-loop/switch region; other site
926550000346	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
926550000347	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000348	dimer interface [polypeptide binding]; other site
926550000349	conserved gate region; other site
926550000350	putative PBP binding loops; other site
926550000351	ABC-ATPase subunit interface; other site
926550000352	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
926550000353	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000354	dimer interface [polypeptide binding]; other site
926550000355	conserved gate region; other site
926550000356	putative PBP binding loops; other site
926550000357	ABC-ATPase subunit interface; other site
926550000358	phosphate binding protein; Region: ptsS_2; TIGR02136
926550000359	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550000360	dimerization interface [polypeptide binding]; other site
926550000361	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550000362	PAS domain; Region: PAS; smart00091
926550000363	putative active site [active]
926550000364	heme pocket [chemical binding]; other site
926550000365	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550000366	dimer interface [polypeptide binding]; other site
926550000367	phosphorylation site [posttranslational modification]
926550000368	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550000369	ATP binding site [chemical binding]; other site
926550000370	Mg2+ binding site [ion binding]; other site
926550000371	G-X-G motif; other site
926550000372	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550000373	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000374	active site
926550000375	phosphorylation site [posttranslational modification]
926550000376	intermolecular recognition site; other site
926550000377	dimerization interface [polypeptide binding]; other site
926550000378	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550000379	DNA binding site [nucleotide binding]
926550000380	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
926550000381	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550000382	active site
926550000383	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000384	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
926550000385	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
926550000386	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
926550000387	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
926550000388	GatB domain; Region: GatB_Yqey; smart00845
926550000389	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550000390	binding surface
926550000391	TPR motif; other site
926550000392	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550000393	binding surface
926550000394	TPR motif; other site
926550000395	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
926550000396	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550000397	binding surface
926550000398	TPR motif; other site
926550000399	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
926550000400	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
926550000401	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926550000402	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926550000403	catalytic residue [active]
926550000404	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550000405	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000406	dimer interface [polypeptide binding]; other site
926550000407	conserved gate region; other site
926550000408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550000409	ABC-ATPase subunit interface; other site
926550000410	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550000411	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000412	dimer interface [polypeptide binding]; other site
926550000413	putative PBP binding loops; other site
926550000414	ABC-ATPase subunit interface; other site
926550000415	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550000416	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
926550000417	nucleotide binding site/active site [active]
926550000418	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926550000419	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926550000420	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926550000421	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
926550000422	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550000423	active site
926550000424	metal binding site [ion binding]; metal-binding site
926550000425	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550000426	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550000427	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550000428	Glutamate-cysteine ligase family 2(GCS2); Region: GCS2; cl00954
926550000429	CHASE domain; Region: CHASE; pfam03924
926550000430	PAS fold; Region: PAS; pfam00989
926550000431	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000432	putative active site [active]
926550000433	heme pocket [chemical binding]; other site
926550000434	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000435	PAS domain; Region: PAS_9; pfam13426
926550000436	putative active site [active]
926550000437	heme pocket [chemical binding]; other site
926550000438	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550000439	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550000440	putative active site [active]
926550000441	heme pocket [chemical binding]; other site
926550000442	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550000443	dimer interface [polypeptide binding]; other site
926550000444	phosphorylation site [posttranslational modification]
926550000445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550000446	ATP binding site [chemical binding]; other site
926550000447	Mg2+ binding site [ion binding]; other site
926550000448	G-X-G motif; other site
926550000449	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550000450	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000451	active site
926550000452	phosphorylation site [posttranslational modification]
926550000453	intermolecular recognition site; other site
926550000454	dimerization interface [polypeptide binding]; other site
926550000455	Response regulator receiver domain; Region: Response_reg; pfam00072
926550000456	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000457	active site
926550000458	phosphorylation site [posttranslational modification]
926550000459	intermolecular recognition site; other site
926550000460	dimerization interface [polypeptide binding]; other site
926550000461	putative Helix-turn-helix domain of transposase IS66; Region: HTH_Tnp_IS66; pfam13005
926550000462	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
926550000463	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
926550000464	metal-binding site
926550000465	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
926550000466	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
926550000467	phenylalanyl-tRNA synthetase, alpha subunit; Region: pheS; TIGR00468
926550000468	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
926550000469	dimer interface [polypeptide binding]; other site
926550000470	motif 1; other site
926550000471	active site
926550000472	motif 2; other site
926550000473	motif 3; other site
926550000474	UGMP family protein; Validated; Region: PRK09604
926550000475	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
926550000476	Peptidase M30; Region: Peptidase_M30; pfam10460
926550000477	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
926550000478	Zn binding site [ion binding]; other site
926550000479	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
926550000480	PA14 domain; Region: PA14; cl08459
926550000481	NHL repeat; Region: NHL; pfam01436
926550000482	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
926550000483	putative active site [active]
926550000484	putative metal binding site [ion binding]; other site
926550000485	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
926550000486	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
926550000487	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
926550000488	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
926550000489	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
926550000490	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
926550000491	dimer interface [polypeptide binding]; other site
926550000492	putative anticodon binding site; other site
926550000493	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
926550000494	motif 1; other site
926550000495	active site
926550000496	motif 2; other site
926550000497	motif 3; other site
926550000498	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
926550000499	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
926550000500	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
926550000501	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550000502	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000503	dimer interface [polypeptide binding]; other site
926550000504	conserved gate region; other site
926550000505	putative PBP binding loops; other site
926550000506	ABC-ATPase subunit interface; other site
926550000507	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
926550000508	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550000509	dimer interface [polypeptide binding]; other site
926550000510	conserved gate region; other site
926550000511	putative PBP binding loops; other site
926550000512	ABC-ATPase subunit interface; other site
926550000513	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550000514	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
926550000515	peptide binding site [polypeptide binding]; other site
926550000516	dimer interface [polypeptide binding]; other site
926550000517	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
926550000518	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
926550000519	active site
926550000520	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
926550000521	O-Antigen ligase; Region: Wzy_C; pfam04932
926550000522	CHAT domain; Region: CHAT; pfam12770
926550000523	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
926550000524	Chain length determinant protein; Region: Wzz; cl15801
926550000525	Predicted membrane protein [Function unknown]; Region: COG3463
926550000526	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
926550000527	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
926550000528	G1P_TT_long represents the long form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_long; cd04189
926550000529	glucose-1-phosphate thymidylylransferase, long form; Region: rmlA_long; TIGR01208
926550000530	substrate binding site; other site
926550000531	metal-binding site
926550000532	Oligomer interface; other site
926550000533	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550000534	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
926550000535	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
926550000536	NAD binding site [chemical binding]; other site
926550000537	substrate binding site [chemical binding]; other site
926550000538	homodimer interface [polypeptide binding]; other site
926550000539	active site
926550000540	H+ Antiporter protein; Region: 2A0121; TIGR00900
926550000541	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550000542	putative substrate translocation pore; other site
926550000543	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926550000544	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
926550000545	metal binding site [ion binding]; metal-binding site
926550000546	dimer interface [polypeptide binding]; other site
926550000547	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926550000548	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
926550000549	putative dimer interface [polypeptide binding]; other site
926550000550	Protein of unknown function (DUF1624); Region: DUF1624; pfam07786
926550000551	DinB superfamily; Region: DinB_2; pfam12867
926550000552	metal-dependent hydrolase; Provisional; Region: PRK13291
926550000553	Protein of unknown function (DUF3891); Region: DUF3891; pfam13030
926550000554	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
926550000555	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
926550000556	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926550000557	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550000558	catalytic loop [active]
926550000559	iron binding site [ion binding]; other site
926550000560	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926550000561	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
926550000562	phosphoribosylaminoimidazole carboxylase ATPase subunit; Reviewed; Region: PRK06019
926550000563	ATP-grasp domain; Region: ATP-grasp; pfam02222
926550000564	Glutamine phosphoribosylpyrophosphate amidotransferase [Nucleotide transport and metabolism]; Region: PurF; COG0034
926550000565	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
926550000566	active site
926550000567	tetramer interface [polypeptide binding]; other site
926550000568	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550000569	active site
926550000570	enoyl-CoA hydratase; Provisional; Region: PRK08140
926550000571	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926550000572	substrate binding site [chemical binding]; other site
926550000573	oxyanion hole (OAH) forming residues; other site
926550000574	trimer interface [polypeptide binding]; other site
926550000575	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
926550000576	Predicted nuclease (RNAse H fold) [General function prediction only]; Region: COG4328
926550000577	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550000578	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550000579	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550000580	Cytochrome c; Region: Cytochrom_C; pfam00034
926550000581	enolase; Provisional; Region: eno; PRK00077
926550000582	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
926550000583	dimer interface [polypeptide binding]; other site
926550000584	metal binding site [ion binding]; metal-binding site
926550000585	substrate binding pocket [chemical binding]; other site
926550000586	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK08217
926550000587	17hydroxysteroid dehydrogenase type 10 (HSD10)-like, classical (c) SDRs; Region: HSD10-like_SDR_c; cd05371
926550000588	NAD binding site [chemical binding]; other site
926550000589	homodimer interface [polypeptide binding]; other site
926550000590	homotetramer interface [polypeptide binding]; other site
926550000591	active site
926550000592	GMP synthase; Reviewed; Region: guaA; PRK00074
926550000593	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
926550000594	AMP/PPi binding site [chemical binding]; other site
926550000595	candidate oxyanion hole; other site
926550000596	catalytic triad [active]
926550000597	potential glutamine specificity residues [chemical binding]; other site
926550000598	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
926550000599	ATP Binding subdomain [chemical binding]; other site
926550000600	Ligand Binding sites [chemical binding]; other site
926550000601	Dimerization subdomain; other site
926550000602	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
926550000603	16S/18S rRNA binding site [nucleotide binding]; other site
926550000604	S13e-L30e interaction site [polypeptide binding]; other site
926550000605	25S rRNA binding site [nucleotide binding]; other site
926550000606	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
926550000607	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
926550000608	RNase E interface [polypeptide binding]; other site
926550000609	trimer interface [polypeptide binding]; other site
926550000610	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
926550000611	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
926550000612	RNase E interface [polypeptide binding]; other site
926550000613	trimer interface [polypeptide binding]; other site
926550000614	active site
926550000615	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
926550000616	putative nucleic acid binding region [nucleotide binding]; other site
926550000617	G-X-X-G motif; other site
926550000618	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
926550000619	RNA binding site [nucleotide binding]; other site
926550000620	domain interface; other site
926550000621	Domain of unknown function DUF20; Region: UPF0118; pfam01594
926550000622	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
926550000623	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
926550000624	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
926550000625	active site
926550000626	dimer interface [polypeptide binding]; other site
926550000627	NurA domain; Region: NurA; pfam09376
926550000628	Mpr1p, Pad1p N-terminal (MPN) domains with catalytic isopeptidase activity (metal-binding); Region: MPN_like; cd08070
926550000629	MPN+ (JAMM) motif; other site
926550000630	Zinc-binding site [ion binding]; other site
926550000631	putative bacillithiol system oxidoreductase, YpdA family; Region: Bthiol_YpdA; TIGR04018
926550000632	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
926550000633	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
926550000634	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
926550000635	bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and...; Region: arch_bact_SO_family_Moco; cd02109
926550000636	Moco binding site; other site
926550000637	metal coordination site [ion binding]; other site
926550000638	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
926550000639	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
926550000640	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550000641	FeS/SAM binding site; other site
926550000642	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
926550000643	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
926550000644	putative catalytic site [active]
926550000645	putative metal binding site [ion binding]; other site
926550000646	putative phosphate binding site [ion binding]; other site
926550000647	Beta-lactamase; Region: Beta-lactamase; pfam00144
926550000648	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
926550000649	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
926550000650	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
926550000651	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
926550000652	Radical SAM superfamily; Region: Radical_SAM; pfam04055
926550000653	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550000654	FeS/SAM binding site; other site
926550000655	Site-specific recombinase XerD [DNA replication, recombination, and repair]; Region: XerD; COG4974
926550000656	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926550000657	active site
926550000658	DNA binding site [nucleotide binding]
926550000659	Int/Topo IB signature motif; other site
926550000660	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: PRK12859
926550000661	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550000662	NAD(P) binding site [chemical binding]; other site
926550000663	active site
926550000664	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
926550000665	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550000666	motif II; other site
926550000667	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_15; cd04673
926550000668	nudix motif; other site
926550000669	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
926550000670	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550000671	substrate binding site [chemical binding]; other site
926550000672	dimer interface [polypeptide binding]; other site
926550000673	ATP binding site [chemical binding]; other site
926550000674	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
926550000675	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
926550000676	hinge; other site
926550000677	active site
926550000678	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
926550000679	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550000680	Mg2+ binding site [ion binding]; other site
926550000681	G-X-G motif; other site
926550000682	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
926550000683	anchoring element; other site
926550000684	dimer interface [polypeptide binding]; other site
926550000685	ATP binding site [chemical binding]; other site
926550000686	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
926550000687	active site
926550000688	putative metal-binding site [ion binding]; other site
926550000689	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
926550000690	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
926550000691	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926550000692	active site
926550000693	NAD binding site [chemical binding]; other site
926550000694	metal binding site [ion binding]; metal-binding site
926550000695	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
926550000696	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
926550000697	active site pocket [active]
926550000698	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550000699	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
926550000700	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
926550000701	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
926550000702	NAD(P) binding site [chemical binding]; other site
926550000703	protein-export membrane protein SecD; Region: secD; TIGR01129
926550000704	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
926550000705	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
926550000706	Protein export membrane protein; Region: SecD_SecF; cl14618
926550000707	Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR_like; cd08242
926550000708	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550000709	putative NAD(P) binding site [chemical binding]; other site
926550000710	catalytic Zn binding site [ion binding]; other site
926550000711	structural Zn binding site [ion binding]; other site
926550000712	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
926550000713	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550000714	RNA binding surface [nucleotide binding]; other site
926550000715	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
926550000716	active site
926550000717	cytidylate kinase; Provisional; Region: cmk; PRK00023
926550000718	AAA domain; Region: AAA_17; pfam13207
926550000719	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
926550000720	CMP-binding site; other site
926550000721	The sites determining sugar specificity; other site
926550000722	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
926550000723	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550000724	tetramer interface [polypeptide binding]; other site
926550000725	TPP-binding site [chemical binding]; other site
926550000726	heterodimer interface [polypeptide binding]; other site
926550000727	phosphorylation loop region [posttranslational modification]
926550000728	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550000729	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926550000730	alpha subunit interface [polypeptide binding]; other site
926550000731	TPP binding site [chemical binding]; other site
926550000732	heterodimer interface [polypeptide binding]; other site
926550000733	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550000734	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
926550000735	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
926550000736	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550000737	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550000738	Walker A/P-loop; other site
926550000739	ATP binding site [chemical binding]; other site
926550000740	Q-loop/lid; other site
926550000741	ABC transporter signature motif; other site
926550000742	Walker B; other site
926550000743	D-loop; other site
926550000744	H-loop/switch region; other site
926550000745	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
926550000746	putative ligand binding site [chemical binding]; other site
926550000747	Glycosyl hydrolases family 35; Region: Glyco_hydro_35; pfam01301
926550000748	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550000749	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926550000750	substrate binding pocket [chemical binding]; other site
926550000751	membrane-bound complex binding site; other site
926550000752	hinge residues; other site
926550000753	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550000754	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926550000755	active site
926550000756	metal binding site [ion binding]; metal-binding site
926550000757	AAA domain; Region: AAA_32; pfam13654
926550000758	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; cl00614
926550000759	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
926550000760	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
926550000761	Predicted membrane protein (DUF2142); Region: DUF2142; pfam09913
926550000762	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550000763	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000764	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550000765	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550000766	Putative threonine efflux protein [Amino acid transport and metabolism]; Region: RhtB; COG1280
926550000767	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550000768	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000769	FG-GAP repeat; Region: FG-GAP; pfam01839
926550000770	Family description; Region: VCBS; pfam13517
926550000771	Family description; Region: VCBS; pfam13517
926550000772	Family description; Region: VCBS; pfam13517
926550000773	Family description; Region: VCBS; pfam13517
926550000774	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550000775	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550000776	active site
926550000777	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000778	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550000779	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550000780	S-adenosylmethionine binding site [chemical binding]; other site
926550000781	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550000782	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550000783	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000784	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
926550000785	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550000786	Probable Catalytic site; other site
926550000787	metal-binding site
926550000788	ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagH; COG1134
926550000789	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
926550000790	Walker A/P-loop; other site
926550000791	ATP binding site [chemical binding]; other site
926550000792	Q-loop/lid; other site
926550000793	ABC transporter signature motif; other site
926550000794	Walker B; other site
926550000795	D-loop; other site
926550000796	H-loop/switch region; other site
926550000797	C-Terminal domain of O-antigenic polysaccharide transporter protein Wzt and related proteins; Region: Wzt_C-like; cd10147
926550000798	putative carbohydrate binding site [chemical binding]; other site
926550000799	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550000800	Glycosyl hydrolase catalytic core; Region: Glyco_hydro_cc; pfam11790
926550000801	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
926550000802	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926550000803	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550000804	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550000805	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550000806	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
926550000807	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550000808	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550000809	TM-ABC transporter signature motif; other site
926550000810	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550000811	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550000812	TM-ABC transporter signature motif; other site
926550000813	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
926550000814	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550000815	Walker A/P-loop; other site
926550000816	ATP binding site [chemical binding]; other site
926550000817	Q-loop/lid; other site
926550000818	ABC transporter signature motif; other site
926550000819	Walker B; other site
926550000820	D-loop; other site
926550000821	H-loop/switch region; other site
926550000822	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550000823	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
926550000824	Periplasmic binding domain of the basic membrane lipoprotein Med in Bacillus and its close homologs from other bacteria and Archaea; Region: PBP1_BmpA_Med_like; cd06353
926550000825	putative ligand binding site [chemical binding]; other site
926550000826	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550000827	Fasciclin domain; Region: Fasciclin; pfam02469
926550000828	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
926550000829	dimer interface [polypeptide binding]; other site
926550000830	[2Fe-2S] cluster binding site [ion binding]; other site
926550000831	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
926550000832	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550000833	RNA binding surface [nucleotide binding]; other site
926550000834	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
926550000835	phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase; Provisional; Region: PRK12324
926550000836	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
926550000837	active site
926550000838	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
926550000839	Divergent AAA domain; Region: AAA_4; pfam04326
926550000840	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
926550000841	Found in ATP-dependent protease La (LON); Region: LON; smart00464
926550000842	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550000843	Walker A motif; other site
926550000844	ATP binding site [chemical binding]; other site
926550000845	Walker B motif; other site
926550000846	arginine finger; other site
926550000847	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
926550000848	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
926550000849	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
926550000850	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
926550000851	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
926550000852	homodimer interface [polypeptide binding]; other site
926550000853	NADP binding site [chemical binding]; other site
926550000854	substrate binding site [chemical binding]; other site
926550000855	RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner; Region: RNase_H; cl14782
926550000856	active site
926550000857	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550000858	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
926550000859	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
926550000860	dimer interface [polypeptide binding]; other site
926550000861	anticodon binding site; other site
926550000862	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926550000863	motif 1; other site
926550000864	dimer interface [polypeptide binding]; other site
926550000865	active site
926550000866	motif 2; other site
926550000867	GAD domain; Region: GAD; pfam02938
926550000868	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926550000869	active site
926550000870	motif 3; other site
926550000871	acyltransferase, WS/DGAT/MGAT; Region: acyl_WS_DGAT; TIGR02946
926550000872	Wax ester synthase-like Acyl-CoA acyltransferase domain; Region: WES_acyltransf; pfam03007
926550000873	Protein of unknown function (DUF1298); Region: DUF1298; pfam06974
926550000874	SNF2 Helicase protein; Region: DUF3670; pfam12419
926550000875	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
926550000876	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550000877	ATP binding site [chemical binding]; other site
926550000878	putative Mg++ binding site [ion binding]; other site
926550000879	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550000880	nucleotide binding region [chemical binding]; other site
926550000881	ATP-binding site [chemical binding]; other site
926550000882	Uncharacterized conserved protein [Function unknown]; Region: COG4279
926550000883	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000884	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000885	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550000886	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000887	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
926550000888	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000889	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000890	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000891	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
926550000892	active site
926550000893	RHS Repeat; Region: RHS_repeat; cl11982
926550000894	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
926550000895	RHS Repeat; Region: RHS_repeat; pfam05593
926550000896	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550000897	RHS Repeat; Region: RHS_repeat; cl11982
926550000898	seryl-tRNA synthetase; Provisional; Region: PRK05431
926550000899	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
926550000900	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
926550000901	dimer interface [polypeptide binding]; other site
926550000902	active site
926550000903	motif 1; other site
926550000904	motif 2; other site
926550000905	motif 3; other site
926550000906	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
926550000907	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
926550000908	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550000909	Walker A motif; other site
926550000910	ATP binding site [chemical binding]; other site
926550000911	Walker B motif; other site
926550000912	arginine finger; other site
926550000913	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
926550000914	Protein of unknown function (DUF2997); Region: DUF2997; pfam11211
926550000915	Protein of unknown function (DUF1257); Region: DUF1257; cl06088
926550000916	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
926550000917	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926550000918	Cysteine-rich domain; Region: CCG; pfam02754
926550000919	Cysteine-rich domain; Region: CCG; pfam02754
926550000920	FAD binding domain; Region: FAD_binding_4; pfam01565
926550000921	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
926550000922	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
926550000923	FAD binding domain; Region: FAD_binding_4; pfam01565
926550000924	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
926550000925	Superfamily II DNA helicase [DNA replication, recombination, and repair]; Region: RecQ; COG0514
926550000926	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550000927	ATP binding site [chemical binding]; other site
926550000928	ATP binding site [chemical binding]; other site
926550000929	putative Mg++ binding site [ion binding]; other site
926550000930	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550000931	nucleotide binding region [chemical binding]; other site
926550000932	ATP-binding site [chemical binding]; other site
926550000933	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
926550000934	HRDC domain; Region: HRDC; pfam00570
926550000935	Protein of unknown function, DUF488; Region: DUF488; pfam04343
926550000936	Protein of unknown function, DUF488; Region: DUF488; pfam04343
926550000937	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
926550000938	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
926550000939	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
926550000940	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
926550000941	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
926550000942	active site
926550000943	glycogen branching enzyme; Provisional; Region: PRK05402
926550000944	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
926550000945	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
926550000946	active site
926550000947	catalytic site [active]
926550000948	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
926550000949	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550000950	Response regulator receiver domain; Region: Response_reg; pfam00072
926550000951	active site
926550000952	phosphorylation site [posttranslational modification]
926550000953	intermolecular recognition site; other site
926550000954	dimerization interface [polypeptide binding]; other site
926550000955	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550000956	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550000957	phosphorylation site [posttranslational modification]
926550000958	dimer interface [polypeptide binding]; other site
926550000959	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
926550000960	Mevalonate kinase [Lipid metabolism]; Region: ERG12; COG1577
926550000961	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
926550000962	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
926550000963	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
926550000964	active site
926550000965	catalytic site [active]
926550000966	metal binding site [ion binding]; metal-binding site
926550000967	dimer interface [polypeptide binding]; other site
926550000968	Restriction endonuclease; Region: Mrr_cat; pfam04471
926550000969	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
926550000970	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550000971	Methylmalonyl-CoA epimerase (MMCE); Region: MMCE; cd07249
926550000972	dimer interface [polypeptide binding]; other site
926550000973	substrate binding site [chemical binding]; other site
926550000974	metal binding site [ion binding]; metal-binding site
926550000975	Melibiase; Region: Melibiase; pfam02065
926550000976	Melibiase; Region: Melibiase; pfam02065
926550000977	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
926550000978	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
926550000979	flavodoxin FldA; Validated; Region: PRK09267
926550000980	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
926550000981	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550000982	Walker A motif; other site
926550000983	ATP binding site [chemical binding]; other site
926550000984	Walker B motif; other site
926550000985	arginine finger; other site
926550000986	Peptidase family M41; Region: Peptidase_M41; pfam01434
926550000987	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
926550000988	catalytic motif [active]
926550000989	Zn binding site [ion binding]; other site
926550000990	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
926550000991	beta-galactosidase; Region: BGL; TIGR03356
926550000992	Poly(hydroxyalcanoate) granule associated protein (phasin); Region: Phasin; cl07863
926550000993	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
926550000994	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550000995	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
926550000996	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
926550000997	Subunit A of Class III extradiol dioxygenases; Region: Extradiol_Dioxygenase_3A_like; cl06673
926550000998	tetramer interface [polypeptide binding]; other site
926550000999	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
926550001000	pyruvate kinase; Provisional; Region: PRK06354
926550001001	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
926550001002	domain interfaces; other site
926550001003	active site
926550001004	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; cl17700
926550001005	Vacuole effluxer Atg22 like; Region: ATG22; pfam11700
926550001006	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
926550001007	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
926550001008	dimer interface [polypeptide binding]; other site
926550001009	active site
926550001010	glycine-pyridoxal phosphate binding site [chemical binding]; other site
926550001011	folate binding site [chemical binding]; other site
926550001012	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550001013	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550001014	DNA binding site [nucleotide binding]
926550001015	domain linker motif; other site
926550001016	Ligand-binding domain of a LacI-like transcriptional regulator, CatR which is involved in catechol degradation; Region: PBP1_CatR_like; cd06296
926550001017	putative dimerization interface [polypeptide binding]; other site
926550001018	putative ligand binding site [chemical binding]; other site
926550001019	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550001020	substrate binding site [chemical binding]; other site
926550001021	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550001022	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550001023	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550001024	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550001025	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001026	dimer interface [polypeptide binding]; other site
926550001027	conserved gate region; other site
926550001028	putative PBP binding loops; other site
926550001029	ABC-ATPase subunit interface; other site
926550001030	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550001031	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550001032	Walker A/P-loop; other site
926550001033	ATP binding site [chemical binding]; other site
926550001034	Q-loop/lid; other site
926550001035	ABC transporter signature motif; other site
926550001036	Walker B; other site
926550001037	D-loop; other site
926550001038	H-loop/switch region; other site
926550001039	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550001040	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550001041	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550001042	Walker A/P-loop; other site
926550001043	ATP binding site [chemical binding]; other site
926550001044	Q-loop/lid; other site
926550001045	ABC transporter signature motif; other site
926550001046	Walker B; other site
926550001047	D-loop; other site
926550001048	H-loop/switch region; other site
926550001049	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
926550001050	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
926550001051	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
926550001052	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
926550001053	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
926550001054	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550001055	active site
926550001056	metal binding site [ion binding]; metal-binding site
926550001057	homotetramer interface [polypeptide binding]; other site
926550001058	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001059	Sortases are cysteine transpeptidases, found in gram-positive bacteria, that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. They do so by catalyzing a transpeptidation reaction in which the surface protein substrate is...; Region: Sortase; cd00004
926550001060	active site
926550001061	catalytic site [active]
926550001062	Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of...; Region: DUF820; cd06260
926550001063	putative active site [active]
926550001064	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550001065	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001066	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550001067	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550001068	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001069	putative PBP binding loops; other site
926550001070	dimer interface [polypeptide binding]; other site
926550001071	ABC-ATPase subunit interface; other site
926550001072	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550001073	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550001074	nucleotide binding site [chemical binding]; other site
926550001075	Protein of unknown function (DUF4127); Region: DUF4127; pfam13552
926550001076	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
926550001077	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
926550001078	putative active site cavity [active]
926550001079	histidine utilization repressor, proteobacterial; Region: his_ut_repres; TIGR02018
926550001080	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550001081	DNA-binding site [nucleotide binding]; DNA binding site
926550001082	UTRA domain; Region: UTRA; pfam07702
926550001083	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550001084	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550001085	ABC transporter; Region: ABC_tran; pfam00005
926550001086	Q-loop/lid; other site
926550001087	ABC transporter signature motif; other site
926550001088	Walker B; other site
926550001089	D-loop; other site
926550001090	H-loop/switch region; other site
926550001091	urea ABC transporter, ATP-binding protein UrtD; Region: urea_trans_UrtD; TIGR03411
926550001092	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550001093	Walker A/P-loop; other site
926550001094	ATP binding site [chemical binding]; other site
926550001095	Q-loop/lid; other site
926550001096	ABC transporter signature motif; other site
926550001097	Walker B; other site
926550001098	D-loop; other site
926550001099	H-loop/switch region; other site
926550001100	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550001101	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550001102	TM-ABC transporter signature motif; other site
926550001103	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550001104	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550001105	TM-ABC transporter signature motif; other site
926550001106	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926550001107	Periplasmic component (FmdD) of an active transport system for short-chain amides and urea (FmdDEF); Region: PBP1_FmdD_like; cd06355
926550001108	putative ligand binding site [chemical binding]; other site
926550001109	urease subunit alpha; Reviewed; Region: ureC; PRK13207
926550001110	Urease alpha-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, fungi and plants. Their primary role is to allow the use of...; Region: Urease_alpha; cd00375
926550001111	subunit interactions [polypeptide binding]; other site
926550001112	active site
926550001113	flap region; other site
926550001114	Urease gamma-subunit; Urease is a nickel-dependent metalloenzyme that catalyzes the hydrolysis of urea to form ammonia and carbon dioxide. Nickel-dependent ureases are found in bacteria, archaea, fungi and plants. Their primary role is to allow the use...; Region: Urease_gamma; cd00390
926550001115	alpha-gamma subunit interface [polypeptide binding]; other site
926550001116	beta-gamma subunit interface [polypeptide binding]; other site
926550001117	UreD urease accessory protein; Region: UreD; pfam01774
926550001118	Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones]; Region: UreF; COG0830
926550001119	UreF; Region: UreF; pfam01730
926550001120	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
926550001121	argininosuccinate synthase; Provisional; Region: PRK13820
926550001122	ANP binding site [chemical binding]; other site
926550001123	Substrate Binding Site II [chemical binding]; other site
926550001124	Substrate Binding Site I [chemical binding]; other site
926550001125	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
926550001126	heterotetramer interface [polypeptide binding]; other site
926550001127	active site pocket [active]
926550001128	cleavage site
926550001129	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
926550001130	active site clefts [active]
926550001131	zinc binding site [ion binding]; other site
926550001132	dimer interface [polypeptide binding]; other site
926550001133	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
926550001134	The tRNA binding domain is also known as the Myf domain in literature. This domain is found in a diverse collection of tRNA binding proteins, including prokaryotic phenylalanyl tRNA synthetases (PheRS), methionyl-tRNA synthetases (MetRS), human...; Region: tRNA_bindingDomain; cl00320
926550001135	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
926550001136	putative tRNA-binding site [nucleotide binding]; other site
926550001137	B3/4 domain; Region: B3_4; pfam03483
926550001138	tRNA synthetase B5 domain; Region: B5; pfam03484
926550001139	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
926550001140	dimer interface [polypeptide binding]; other site
926550001141	motif 1; other site
926550001142	motif 3; other site
926550001143	motif 2; other site
926550001144	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
926550001145	Inosine-uridine preferring nucleoside hydrolase; Region: IU_nuc_hydro; pfam01156
926550001146	active site
926550001147	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
926550001148	PA14 domain; Region: PA14; cl08459
926550001149	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550001150	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550001151	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001152	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550001153	Domain of unknown function DUF59; Region: DUF59; pfam01883
926550001154	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
926550001155	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
926550001156	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550001157	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001158	active site
926550001159	phosphorylation site [posttranslational modification]
926550001160	intermolecular recognition site; other site
926550001161	dimerization interface [polypeptide binding]; other site
926550001162	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550001163	DNA binding residues [nucleotide binding]
926550001164	dimerization interface [polypeptide binding]; other site
926550001165	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550001166	dimerization interface [polypeptide binding]; other site
926550001167	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
926550001168	Histidine kinase; Region: HisKA_3; pfam07730
926550001169	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001170	ATP binding site [chemical binding]; other site
926550001171	Mg2+ binding site [ion binding]; other site
926550001172	G-X-G motif; other site
926550001173	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
926550001174	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
926550001175	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550001176	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550001177	catalytic residues [active]
926550001178	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926550001179	4Fe-4S binding domain; Region: Fer4; cl02805
926550001180	4Fe-4S binding domain; Region: Fer4; pfam00037
926550001181	Cysteine-rich domain; Region: CCG; pfam02754
926550001182	Cysteine-rich domain; Region: CCG; pfam02754
926550001183	Beta-lactamase; Region: Beta-lactamase; pfam00144
926550001184	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
926550001185	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
926550001186	Zn binding site [ion binding]; other site
926550001187	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550001188	catalytic core [active]
926550001189	Protein of unknown function (DUF3090); Region: DUF3090; cl12832
926550001190	conserved hypothetical protein; Region: TIGR03843
926550001191	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
926550001192	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
926550001193	active site
926550001194	Substrate binding site; other site
926550001195	Mg++ binding site; other site
926550001196	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550001197	putative trimer interface [polypeptide binding]; other site
926550001198	putative CoA binding site [chemical binding]; other site
926550001199	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550001200	phosphoglucosamine mutase; Region: Arch_GlmM; TIGR03990
926550001201	The alpha-D-phosphohexomutase superfamily includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Members of this family include the phosphoglucomutases (PGM1 and PGM2), phosphoglucosamine...; Region: phosphohexomutase; cl03757
926550001202	active site
926550001203	substrate binding site [chemical binding]; other site
926550001204	metal binding site [ion binding]; metal-binding site
926550001205	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
926550001206	Arginase family; Region: Arginase; cd09989
926550001207	agmatinase; Region: agmatinase; TIGR01230
926550001208	active site
926550001209	Mn binding site [ion binding]; other site
926550001210	oligomer interface [polypeptide binding]; other site
926550001211	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926550001212	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
926550001213	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926550001214	HSP70 interaction site [polypeptide binding]; other site
926550001215	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550001216	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
926550001217	Domain of unknown function DUF20; Region: UPF0118; pfam01594
926550001218	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
926550001219	Part of AAA domain; Region: AAA_19; pfam13245
926550001220	Family description; Region: UvrD_C_2; pfam13538
926550001221	GTPase RsgA; Reviewed; Region: PRK00098
926550001222	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
926550001223	RNA binding site [nucleotide binding]; other site
926550001224	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
926550001225	GTPase/Zn-binding domain interface [polypeptide binding]; other site
926550001226	GTP/Mg2+ binding site [chemical binding]; other site
926550001227	G4 box; other site
926550001228	G5 box; other site
926550001229	G1 box; other site
926550001230	Switch I region; other site
926550001231	G2 box; other site
926550001232	G3 box; other site
926550001233	Switch II region; other site
926550001234	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550001235	GAF domain; Region: GAF_3; pfam13492
926550001236	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550001237	putative active site [active]
926550001238	PAS fold; Region: PAS_3; pfam08447
926550001239	heme pocket [chemical binding]; other site
926550001240	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550001241	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550001242	dimer interface [polypeptide binding]; other site
926550001243	phosphorylation site [posttranslational modification]
926550001244	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001245	ATP binding site [chemical binding]; other site
926550001246	Mg2+ binding site [ion binding]; other site
926550001247	G-X-G motif; other site
926550001248	Response regulator receiver domain; Region: Response_reg; pfam00072
926550001249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001250	active site
926550001251	phosphorylation site [posttranslational modification]
926550001252	intermolecular recognition site; other site
926550001253	dimerization interface [polypeptide binding]; other site
926550001254	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550001255	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550001256	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550001257	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550001258	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550001259	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550001260	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550001261	dimer interface [polypeptide binding]; other site
926550001262	phosphorylation site [posttranslational modification]
926550001263	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001264	ATP binding site [chemical binding]; other site
926550001265	Mg2+ binding site [ion binding]; other site
926550001266	G-X-G motif; other site
926550001267	Response regulator receiver domain; Region: Response_reg; pfam00072
926550001268	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001269	active site
926550001270	phosphorylation site [posttranslational modification]
926550001271	intermolecular recognition site; other site
926550001272	dimerization interface [polypeptide binding]; other site
926550001273	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550001274	PAS fold; Region: PAS_3; pfam08447
926550001275	putative active site [active]
926550001276	heme pocket [chemical binding]; other site
926550001277	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550001278	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550001279	putative active site [active]
926550001280	heme pocket [chemical binding]; other site
926550001281	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550001282	dimer interface [polypeptide binding]; other site
926550001283	phosphorylation site [posttranslational modification]
926550001284	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001285	ATP binding site [chemical binding]; other site
926550001286	Mg2+ binding site [ion binding]; other site
926550001287	G-X-G motif; other site
926550001288	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
926550001289	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550001290	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550001291	putative substrate translocation pore; other site
926550001292	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550001293	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
926550001294	conserved cys residue [active]
926550001295	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550001296	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001297	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550001298	Maf-like protein; Region: Maf; pfam02545
926550001299	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
926550001300	active site
926550001301	dimer interface [polypeptide binding]; other site
926550001302	Uncharacterized conserved protein [Function unknown]; Region: COG0062
926550001303	Competence-damaged protein; Region: CinA; pfam02464
926550001304	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550001305	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
926550001306	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
926550001307	phosphate binding site [ion binding]; other site
926550001308	putative substrate binding pocket [chemical binding]; other site
926550001309	dimer interface [polypeptide binding]; other site
926550001310	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
926550001311	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
926550001312	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
926550001313	Phosphoglycerate kinase; Region: PGK; pfam00162
926550001314	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
926550001315	substrate binding site [chemical binding]; other site
926550001316	hinge regions; other site
926550001317	ADP binding site [chemical binding]; other site
926550001318	catalytic site [active]
926550001319	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
926550001320	triosephosphate isomerase; Provisional; Region: PRK14565
926550001321	substrate binding site [chemical binding]; other site
926550001322	dimer interface [polypeptide binding]; other site
926550001323	catalytic triad [active]
926550001324	Transmembrane exosortase (Exosortase_EpsH); Region: Exosortase_EpsH; pfam09721
926550001325	Predicted membrane protein [Function unknown]; Region: COG4083; cl15694
926550001326	Protein of unknown function (DUF3485); Region: DUF3485; cl11827
926550001327	SnoaL-like domain; Region: SnoaL_3; pfam13474
926550001328	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550001329	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550001330	catalytic residues [active]
926550001331	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
926550001332	putative active site [active]
926550001333	transaldolase; Provisional; Region: PRK03903
926550001334	catalytic residue [active]
926550001335	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
926550001336	MPT binding site; other site
926550001337	trimer interface [polypeptide binding]; other site
926550001338	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
926550001339	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
926550001340	23S rRNA interface [nucleotide binding]; other site
926550001341	L3 interface [polypeptide binding]; other site
926550001342	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
926550001343	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
926550001344	dimerization interface 3.5A [polypeptide binding]; other site
926550001345	active site
926550001346	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
926550001347	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
926550001348	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
926550001349	alphaNTD homodimer interface [polypeptide binding]; other site
926550001350	alphaNTD - beta interaction site [polypeptide binding]; other site
926550001351	alphaNTD - beta' interaction site [polypeptide binding]; other site
926550001352	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
926550001353	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
926550001354	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
926550001355	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550001356	RNA binding surface [nucleotide binding]; other site
926550001357	30S ribosomal protein S11; Validated; Region: PRK05309
926550001358	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
926550001359	30S ribosomal protein S13; Region: bact_S13; TIGR03631
926550001360	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
926550001361	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
926550001362	active site
926550001363	adenylate kinase; Reviewed; Region: adk; PRK00279
926550001364	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
926550001365	AMP-binding site [chemical binding]; other site
926550001366	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
926550001367	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
926550001368	SecY translocase; Region: SecY; pfam00344
926550001369	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
926550001370	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
926550001371	23S rRNA binding site [nucleotide binding]; other site
926550001372	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
926550001373	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
926550001374	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
926550001375	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
926550001376	5S rRNA interface [nucleotide binding]; other site
926550001377	23S rRNA interface [nucleotide binding]; other site
926550001378	L5 interface [polypeptide binding]; other site
926550001379	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
926550001380	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
926550001381	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
926550001382	Ribosomal protein S8; Region: Ribosomal_S8; cl00330
926550001383	Ribosomal protein S14p/S29e; Region: Ribosomal_S14; cl00355
926550001384	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
926550001385	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
926550001386	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
926550001387	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
926550001388	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
926550001389	RNA binding site [nucleotide binding]; other site
926550001390	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
926550001391	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
926550001392	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
926550001393	putative translocon interaction site; other site
926550001394	23S rRNA interface [nucleotide binding]; other site
926550001395	signal recognition particle (SRP54) interaction site; other site
926550001396	L23 interface [polypeptide binding]; other site
926550001397	trigger factor interaction site; other site
926550001398	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
926550001399	23S rRNA interface [nucleotide binding]; other site
926550001400	5S rRNA interface [nucleotide binding]; other site
926550001401	putative antibiotic binding site [chemical binding]; other site
926550001402	L25 interface [polypeptide binding]; other site
926550001403	L27 interface [polypeptide binding]; other site
926550001404	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
926550001405	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
926550001406	G-X-X-G motif; other site
926550001407	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
926550001408	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
926550001409	protein-rRNA interface [nucleotide binding]; other site
926550001410	putative translocon binding site; other site
926550001411	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
926550001412	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
926550001413	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
926550001414	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
926550001415	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
926550001416	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
926550001417	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
926550001418	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
926550001419	elongation factor Tu; Reviewed; Region: PRK00049
926550001420	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
926550001421	GEF interaction site [polypeptide binding]; other site
926550001422	GTP/Mg2+ binding site [chemical binding]; other site
926550001423	Switch I region; other site
926550001424	G2 box; other site
926550001425	G3 box; other site
926550001426	Switch II region; other site
926550001427	G4 box; other site
926550001428	G5 box; other site
926550001429	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
926550001430	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
926550001431	Antibiotic Binding Site [chemical binding]; other site
926550001432	elongation factor G; Reviewed; Region: PRK00007
926550001433	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
926550001434	G1 box; other site
926550001435	putative GEF interaction site [polypeptide binding]; other site
926550001436	GTP/Mg2+ binding site [chemical binding]; other site
926550001437	Switch I region; other site
926550001438	G2 box; other site
926550001439	G3 box; other site
926550001440	Switch II region; other site
926550001441	G4 box; other site
926550001442	G5 box; other site
926550001443	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
926550001444	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
926550001445	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
926550001446	30S ribosomal protein S7; Validated; Region: PRK05302
926550001447	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
926550001448	S17 interaction site [polypeptide binding]; other site
926550001449	S8 interaction site; other site
926550001450	16S rRNA interaction site [nucleotide binding]; other site
926550001451	streptomycin interaction site [chemical binding]; other site
926550001452	23S rRNA interaction site [nucleotide binding]; other site
926550001453	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
926550001454	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
926550001455	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
926550001456	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926550001457	catalytic residue [active]
926550001458	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
926550001459	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
926550001460	DNA binding residues [nucleotide binding]
926550001461	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550001462	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
926550001463	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550001464	ATP binding site [chemical binding]; other site
926550001465	putative Mg++ binding site [ion binding]; other site
926550001466	FYVE domain; Zinc-binding domain; targets proteins to membrane lipids via interaction with phosphatidylinositol-3-phosphate, PI3P; present in Fab1, YOTB, Vac1, and EEA1; Region: FYVE; cl17764
926550001467	phosphatidylinositol 3-phosphate binding site [chemical binding]; other site
926550001468	Zn binding sites [ion binding]; other site
926550001469	helicase superfamily c-terminal domain; Region: HELICc; smart00490
926550001470	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
926550001471	ribonuclease P; Reviewed; Region: rnpA; PRK00499
926550001472	Haemolytic domain; Region: Haemolytic; pfam01809
926550001473	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
926550001474	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
926550001475	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
926550001476	G-X-X-G motif; other site
926550001477	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
926550001478	RxxxH motif; other site
926550001479	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550001480	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926550001481	substrate binding site [chemical binding]; other site
926550001482	ATP binding site [chemical binding]; other site
926550001483	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926550001484	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926550001485	P-loop; other site
926550001486	Magnesium ion binding site [ion binding]; other site
926550001487	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926550001488	Magnesium ion binding site [ion binding]; other site
926550001489	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
926550001490	ParB-like nuclease domain; Region: ParB; smart00470
926550001491	KorB domain; Region: KorB; pfam08535
926550001492	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550001493	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001494	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
926550001495	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
926550001496	DNA binding residues [nucleotide binding]
926550001497	B12 binding domain; Region: B12-binding_2; pfam02607
926550001498	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cd02065
926550001499	B12 binding site [chemical binding]; other site
926550001500	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
926550001501	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550001502	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550001503	ligand binding site [chemical binding]; other site
926550001504	flexible hinge region; other site
926550001505	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926550001506	putative switch regulator; other site
926550001507	non-specific DNA interactions [nucleotide binding]; other site
926550001508	DNA binding site [nucleotide binding]
926550001509	sequence specific DNA binding site [nucleotide binding]; other site
926550001510	putative cAMP binding site [chemical binding]; other site
926550001511	transcription termination factor Rho; Provisional; Region: rho; PRK09376
926550001512	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
926550001513	RNA binding site [nucleotide binding]; other site
926550001514	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
926550001515	multimer interface [polypeptide binding]; other site
926550001516	Walker A motif; other site
926550001517	ATP binding site [chemical binding]; other site
926550001518	Walker B motif; other site
926550001519	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550001520	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001521	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001522	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550001523	fumarate hydratase; Reviewed; Region: fumC; PRK00485
926550001524	Class II fumarases; Region: Fumarase_classII; cd01362
926550001525	active site
926550001526	tetramer interface [polypeptide binding]; other site
926550001527	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
926550001528	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001529	active site
926550001530	phosphorylation site [posttranslational modification]
926550001531	intermolecular recognition site; other site
926550001532	dimerization interface [polypeptide binding]; other site
926550001533	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550001534	DNA binding site [nucleotide binding]
926550001535	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
926550001536	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550001537	dimerization interface [polypeptide binding]; other site
926550001538	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550001539	dimer interface [polypeptide binding]; other site
926550001540	phosphorylation site [posttranslational modification]
926550001541	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001542	ATP binding site [chemical binding]; other site
926550001543	Mg2+ binding site [ion binding]; other site
926550001544	G-X-G motif; other site
926550001545	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
926550001546	Divergent AAA domain; Region: AAA_4; pfam04326
926550001547	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
926550001548	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
926550001549	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
926550001550	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550001551	S-adenosylmethionine binding site [chemical binding]; other site
926550001552	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550001553	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550001554	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550001555	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550001556	Uncharacterized conserved protein [Function unknown]; Region: COG0062
926550001557	putative carbohydrate kinase; Provisional; Region: PRK10565
926550001558	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
926550001559	putative substrate binding site [chemical binding]; other site
926550001560	putative ATP binding site [chemical binding]; other site
926550001561	monogalactosyldiacylglycerol synthase; Region: PLN02605
926550001562	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
926550001563	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550001564	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
926550001565	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001566	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926550001567	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550001568	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550001569	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550001570	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550001571	Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: ArsA; COG0003
926550001572	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
926550001573	P loop; other site
926550001574	Nucleotide binding site [chemical binding]; other site
926550001575	DTAP/Switch II; other site
926550001576	Switch I; other site
926550001577	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
926550001578	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
926550001579	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
926550001580	putative catalytic cysteine [active]
926550001581	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
926550001582	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
926550001583	homodimer interface [polypeptide binding]; other site
926550001584	substrate-cofactor binding pocket; other site
926550001585	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550001586	catalytic residue [active]
926550001587	Protein of unknown function (DUF3048); Region: DUF3048; pfam11258
926550001588	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550001589	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001590	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001591	Family description; Region: VCBS; pfam13517
926550001592	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550001593	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550001594	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
926550001595	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550001596	active site
926550001597	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550001598	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550001599	dimer interface [polypeptide binding]; other site
926550001600	phosphorylation site [posttranslational modification]
926550001601	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550001602	ATP binding site [chemical binding]; other site
926550001603	Mg2+ binding site [ion binding]; other site
926550001604	G-X-G motif; other site
926550001605	Response regulator receiver domain; Region: Response_reg; pfam00072
926550001606	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001607	active site
926550001608	phosphorylation site [posttranslational modification]
926550001609	intermolecular recognition site; other site
926550001610	dimerization interface [polypeptide binding]; other site
926550001611	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
926550001612	Predicted dinucleotide-binding enzymes [General function prediction only]; Region: COG2085
926550001613	cystathionine gamma-synthase; Provisional; Region: PRK07811
926550001614	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926550001615	homodimer interface [polypeptide binding]; other site
926550001616	substrate-cofactor binding pocket; other site
926550001617	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550001618	catalytic residue [active]
926550001619	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926550001620	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
926550001621	Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system [Function unknown]; Region: COG4946
926550001622	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550001623	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
926550001624	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
926550001625	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
926550001626	protein binding site [polypeptide binding]; other site
926550001627	Tricorn protease; serine protease family S41; Region: Peptidase_S41_TRI; cd07562
926550001628	Domain interface; other site
926550001629	Peptide binding site; other site
926550001630	Active site tetrad [active]
926550001631	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550001632	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550001633	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
926550001634	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001635	conserved gate region; other site
926550001636	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550001637	ABC-ATPase subunit interface; other site
926550001638	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550001639	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001640	dimer interface [polypeptide binding]; other site
926550001641	conserved gate region; other site
926550001642	putative PBP binding loops; other site
926550001643	ABC-ATPase subunit interface; other site
926550001644	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
926550001645	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
926550001646	active site
926550001647	homodimer interface [polypeptide binding]; other site
926550001648	catalytic site [active]
926550001649	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
926550001650	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
926550001651	Glycerophosphodiester phosphodiesterase domain of Agrobacterium tumefaciens and similar proteins; Region: GDPD_AtGDE_like; cd08566
926550001652	putative active site [active]
926550001653	catalytic site [active]
926550001654	putative metal binding site [ion binding]; other site
926550001655	oligomer interface [polypeptide binding]; other site
926550001656	Saccharomyces cerevisiae homocitrate synthase and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_HCS; cd07948
926550001657	homocitrate synthase; Region: LysS_fung_arch; TIGR02146
926550001658	active site
926550001659	catalytic residues [active]
926550001660	metal binding site [ion binding]; metal-binding site
926550001661	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
926550001662	dimer interface [polypeptide binding]; other site
926550001663	ADP-ribose binding site [chemical binding]; other site
926550001664	active site
926550001665	nudix motif; other site
926550001666	metal binding site [ion binding]; metal-binding site
926550001667	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550001668	Coenzyme A binding pocket [chemical binding]; other site
926550001669	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
926550001670	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
926550001671	substrate binding site [chemical binding]; other site
926550001672	ligand binding site [chemical binding]; other site
926550001673	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
926550001674	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
926550001675	substrate binding site [chemical binding]; other site
926550001676	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_21; cd04680
926550001677	nudix motif; other site
926550001678	tartrate dehydrogenase; Region: TTC; TIGR02089
926550001679	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
926550001680	lysine biosynthesis protein LysW; Region: lysW; TIGR01206
926550001681	Lysine biosynthesis enzyme LysX; Region: LysX_arch; TIGR02144
926550001682	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550001683	L-ribulokinase-like proteins; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-RBK_like; cd07778
926550001684	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550001685	putative N- and C-terminal domain interface [polypeptide binding]; other site
926550001686	putative active site [active]
926550001687	MgATP binding site [chemical binding]; other site
926550001688	catalytic site [active]
926550001689	metal binding site [ion binding]; metal-binding site
926550001690	putative carbohydrate binding site [chemical binding]; other site
926550001691	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
926550001692	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
926550001693	Cytochrome c554 and c-prime; Region: Cytochrome_C554; pfam13435
926550001694	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
926550001695	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
926550001696	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926550001697	substrate binding site [chemical binding]; other site
926550001698	oxyanion hole (OAH) forming residues; other site
926550001699	trimer interface [polypeptide binding]; other site
926550001700	VPS10 domain; Region: VPS10; smart00602
926550001701	Glucokinase; Region: Glucokinase; pfam02685
926550001702	glucokinase, proteobacterial type; Region: glk; TIGR00749
926550001703	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
926550001704	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550001705	active site
926550001706	dimer interface [polypeptide binding]; other site
926550001707	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
926550001708	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
926550001709	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550001710	Walker A motif; other site
926550001711	ATP binding site [chemical binding]; other site
926550001712	Walker B motif; other site
926550001713	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
926550001714	Sortase E (SrtE) is a membrane transpeptidase found in gram-positive bacteria that cleaves surface proteins at a cell sorting motif and catalyzes a transpeptidation reaction in which the surface protein substrate is covalently linked to peptidoglycan for...; Region: Sortase_E; cd05829
926550001715	active site
926550001716	putative catalytic site [active]
926550001717	Plastocyanin [Energy production and conversion]; Region: PetE; COG3794
926550001718	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
926550001719	Anti-sigma-K factor rskA; Region: RskA; pfam10099
926550001720	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
926550001721	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550001722	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550001723	DNA binding residues [nucleotide binding]
926550001724	CobB/CobQ-like glutamine amidotransferase domain; Region: GATase_5; pfam13507
926550001725	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
926550001726	conserved cys residue [active]
926550001727	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; cl00789
926550001728	Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain [Nucleotide transport and metabolism]; Region: PurL; COG0046
926550001729	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
926550001730	dimerization interface [polypeptide binding]; other site
926550001731	ATP binding site [chemical binding]; other site
926550001732	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
926550001733	dimerization interface [polypeptide binding]; other site
926550001734	ATP binding site [chemical binding]; other site
926550001735	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
926550001736	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
926550001737	RNA binding site [nucleotide binding]; other site
926550001738	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
926550001739	RNA binding site [nucleotide binding]; other site
926550001740	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
926550001741	RNA binding site [nucleotide binding]; other site
926550001742	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
926550001743	RNA binding site [nucleotide binding]; other site
926550001744	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
926550001745	homotrimer interaction site [polypeptide binding]; other site
926550001746	putative active site [active]
926550001747	rod shape-determining protein MreB; Provisional; Region: PRK13927
926550001748	MreB and similar proteins; Region: MreB_like; cd10225
926550001749	nucleotide binding site [chemical binding]; other site
926550001750	Mg binding site [ion binding]; other site
926550001751	putative protofilament interaction site [polypeptide binding]; other site
926550001752	RodZ interaction site [polypeptide binding]; other site
926550001753	F0F1 ATP synthase subunit epsilon; Provisional; Region: atpC; PRK13446
926550001754	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
926550001755	gamma subunit interface [polypeptide binding]; other site
926550001756	epsilon subunit interface [polypeptide binding]; other site
926550001757	LBP interface [polypeptide binding]; other site
926550001758	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
926550001759	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
926550001760	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
926550001761	alpha subunit interaction interface [polypeptide binding]; other site
926550001762	Walker A motif; other site
926550001763	ATP binding site [chemical binding]; other site
926550001764	Walker B motif; other site
926550001765	inhibitor binding site; inhibition site
926550001766	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
926550001767	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
926550001768	core domain interface [polypeptide binding]; other site
926550001769	delta subunit interface [polypeptide binding]; other site
926550001770	epsilon subunit interface [polypeptide binding]; other site
926550001771	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
926550001772	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
926550001773	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
926550001774	beta subunit interaction interface [polypeptide binding]; other site
926550001775	Walker A motif; other site
926550001776	ATP binding site [chemical binding]; other site
926550001777	Walker B motif; other site
926550001778	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
926550001779	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
926550001780	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
926550001781	ATP synthase B/B' CF(0); Region: ATP-synt_B; cl17192
926550001782	F0F1 ATP synthase subunit B; Provisional; Region: PRK13461
926550001783	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
926550001784	ATP synthase A chain; Region: ATP-synt_A; cl00413
926550001785	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
926550001786	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; cl09754
926550001787	Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]; Region: LacZ; COG3250
926550001788	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
926550001789	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550001790	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550001791	Uncharacterized conserved protein [Function unknown]; Region: COG1284
926550001792	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
926550001793	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
926550001794	Double zinc ribbon; Region: DZR; pfam12773
926550001795	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
926550001796	MutL protein; Region: MutL; pfam13941
926550001797	Nitroreductase-like family 2. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_2; cd02138
926550001798	putative FMN binding site [chemical binding]; other site
926550001799	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926550001800	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
926550001801	Response regulator receiver domain; Region: Response_reg; pfam00072
926550001802	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550001803	active site
926550001804	phosphorylation site [posttranslational modification]
926550001805	intermolecular recognition site; other site
926550001806	dimerization interface [polypeptide binding]; other site
926550001807	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
926550001808	cyclase homology domain; Region: CHD; cd07302
926550001809	nucleotidyl binding site; other site
926550001810	metal binding site [ion binding]; metal-binding site
926550001811	dimer interface [polypeptide binding]; other site
926550001812	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550001813	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
926550001814	Peptidase S8 family domain in BacillopeptidaseF-like proteins; Region: Peptidases_S8_BacillopeptidaseF-like; cd07481
926550001815	active site
926550001816	catalytic triad [active]
926550001817	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
926550001818	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
926550001819	catalytic triad [active]
926550001820	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
926550001821	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
926550001822	selenium-dependent molybdenum hydroxylase 1; Region: Se_dep_Molyb_1; TIGR03311
926550001823	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550001824	catalytic loop [active]
926550001825	iron binding site [ion binding]; other site
926550001826	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926550001827	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926550001828	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926550001829	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
926550001830	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926550001831	tetramer interface [polypeptide binding]; other site
926550001832	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550001833	catalytic residue [active]
926550001834	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
926550001835	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001836	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001837	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926550001838	metal binding site [ion binding]; metal-binding site
926550001839	DinB family; Region: DinB; cl17821
926550001840	DinB superfamily; Region: DinB_2; pfam12867
926550001841	Prolipoprotein diacylglyceryl transferase; Region: LGT; pfam01790
926550001842	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
926550001843	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550001844	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550001845	homodimer interface [polypeptide binding]; other site
926550001846	catalytic residue [active]
926550001847	4-aminobutyrate aminotransferase; Provisional; Region: PRK08117
926550001848	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550001849	inhibitor-cofactor binding pocket; inhibition site
926550001850	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550001851	catalytic residue [active]
926550001852	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926550001853	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550001854	substrate binding pocket [chemical binding]; other site
926550001855	membrane-bound complex binding site; other site
926550001856	hinge residues; other site
926550001857	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
926550001858	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001859	dimer interface [polypeptide binding]; other site
926550001860	conserved gate region; other site
926550001861	putative PBP binding loops; other site
926550001862	ABC-ATPase subunit interface; other site
926550001863	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926550001864	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
926550001865	Walker A/P-loop; other site
926550001866	ATP binding site [chemical binding]; other site
926550001867	Q-loop/lid; other site
926550001868	ABC transporter signature motif; other site
926550001869	Walker B; other site
926550001870	D-loop; other site
926550001871	H-loop/switch region; other site
926550001872	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
926550001873	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001874	dimer interface [polypeptide binding]; other site
926550001875	conserved gate region; other site
926550001876	putative PBP binding loops; other site
926550001877	ABC-ATPase subunit interface; other site
926550001878	Family description; Region: VCBS; pfam13517
926550001879	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
926550001880	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
926550001881	Strictosidine synthase; Region: Str_synth; pfam03088
926550001882	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
926550001883	MutS domain I; Region: MutS_I; pfam01624
926550001884	MutS domain II; Region: MutS_II; pfam05188
926550001885	MutS domain III; Region: MutS_III; pfam05192
926550001886	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
926550001887	Walker A/P-loop; other site
926550001888	ATP binding site [chemical binding]; other site
926550001889	Q-loop/lid; other site
926550001890	ABC transporter signature motif; other site
926550001891	Walker B; other site
926550001892	D-loop; other site
926550001893	H-loop/switch region; other site
926550001894	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
926550001895	MutS domain III; Region: MutS_III; pfam05192
926550001896	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
926550001897	Walker A/P-loop; other site
926550001898	ATP binding site [chemical binding]; other site
926550001899	Q-loop/lid; other site
926550001900	ABC transporter signature motif; other site
926550001901	Walker B; other site
926550001902	D-loop; other site
926550001903	H-loop/switch region; other site
926550001904	Smr domain; Region: Smr; pfam01713
926550001905	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550001906	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550001907	active site
926550001908	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550001909	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926550001910	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926550001911	putative active site [active]
926550001912	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
926550001913	putative active site [active]
926550001914	putative metal binding site [ion binding]; other site
926550001915	Predicted permeases [General function prediction only]; Region: COG0679
926550001916	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926550001917	Peptidase C26; Region: Peptidase_C26; pfam07722
926550001918	catalytic triad [active]
926550001919	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
926550001920	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
926550001921	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550001922	catalytic residue [active]
926550001923	AAK_FomA-like: This CD includes a fosfomycin biosynthetic gene product, FomA, and similar proteins found in a wide range of organisms. Together, the fomA and fomB genes in the fosfomycin biosynthetic gene cluster of Streptomyces wedmorensis confer...; Region: AAK_FomA-like; cd04241
926550001924	putative nucleotide binding site [chemical binding]; other site
926550001925	putative substrate binding site [chemical binding]; other site
926550001926	RIP metalloprotease RseP; Region: TIGR00054
926550001927	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
926550001928	active site
926550001929	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
926550001930	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
926550001931	protein binding site [polypeptide binding]; other site
926550001932	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
926550001933	putative substrate binding region [chemical binding]; other site
926550001934	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001935	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550001936	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550001937	HEAT repeats; Region: HEAT_2; pfam13646
926550001938	Predicted permeases [General function prediction only]; Region: COG0679
926550001939	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
926550001940	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550001941	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550001942	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550001943	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
926550001944	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
926550001945	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550001946	active site
926550001947	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550001948	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926550001949	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
926550001950	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
926550001951	active site
926550001952	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
926550001953	homotrimer interaction site [polypeptide binding]; other site
926550001954	putative active site [active]
926550001955	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
926550001956	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
926550001957	Ligand Binding Site [chemical binding]; other site
926550001958	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550001959	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550001960	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550001961	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001962	dimer interface [polypeptide binding]; other site
926550001963	conserved gate region; other site
926550001964	putative PBP binding loops; other site
926550001965	ABC-ATPase subunit interface; other site
926550001966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001967	putative PBP binding loops; other site
926550001968	dimer interface [polypeptide binding]; other site
926550001969	ABC-ATPase subunit interface; other site
926550001970	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
926550001971	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
926550001972	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
926550001973	active site
926550001974	homotrimer interface [polypeptide binding]; other site
926550001975	catalytic site [active]
926550001976	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
926550001977	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550001978	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550001979	DNA binding site [nucleotide binding]
926550001980	domain linker motif; other site
926550001981	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550001982	ligand binding site [chemical binding]; other site
926550001983	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550001984	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550001985	DNA binding site [nucleotide binding]
926550001986	domain linker motif; other site
926550001987	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550001988	dimerization interface [polypeptide binding]; other site
926550001989	ligand binding site [chemical binding]; other site
926550001990	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550001991	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550001992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550001993	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001994	dimer interface [polypeptide binding]; other site
926550001995	ABC-ATPase subunit interface; other site
926550001996	putative PBP binding loops; other site
926550001997	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550001998	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550001999	dimer interface [polypeptide binding]; other site
926550002000	conserved gate region; other site
926550002001	putative PBP binding loops; other site
926550002002	ABC-ATPase subunit interface; other site
926550002003	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
926550002004	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550002005	CHAT domain; Region: CHAT; pfam12770
926550002006	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002007	TPR motif; other site
926550002008	binding surface
926550002009	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
926550002010	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
926550002011	NADP-binding site; other site
926550002012	homotetramer interface [polypeptide binding]; other site
926550002013	substrate binding site [chemical binding]; other site
926550002014	homodimer interface [polypeptide binding]; other site
926550002015	active site
926550002016	HEAT repeats; Region: HEAT_2; pfam13646
926550002017	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550002018	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
926550002019	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
926550002020	trimer interface [polypeptide binding]; other site
926550002021	putative metal binding site [ion binding]; other site
926550002022	kynureninase; Region: kynureninase; TIGR01814
926550002023	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550002024	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550002025	catalytic residue [active]
926550002026	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926550002027	AsnC family; Region: AsnC_trans_reg; pfam01037
926550002028	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
926550002029	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
926550002030	putative dimer interface [polypeptide binding]; other site
926550002031	[2Fe-2S] cluster binding site [ion binding]; other site
926550002032	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
926550002033	SLBB domain; Region: SLBB; pfam10531
926550002034	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
926550002035	bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569
926550002036	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550002037	catalytic loop [active]
926550002038	iron binding site [ion binding]; other site
926550002039	4Fe-4S binding domain; Region: Fer4; pfam00037
926550002040	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
926550002041	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
926550002042	active site
926550002043	interdomain interaction site; other site
926550002044	putative metal-binding site [ion binding]; other site
926550002045	nucleotide binding site [chemical binding]; other site
926550002046	Bacterial DNA topoisomeraes I ATP-binding domain; Region: TOP1Bc; smart00436
926550002047	domain I; other site
926550002048	phosphate binding site [ion binding]; other site
926550002049	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
926550002050	domain II; other site
926550002051	domain III; other site
926550002052	nucleotide binding site [chemical binding]; other site
926550002053	DNA binding groove [nucleotide binding]
926550002054	catalytic site [active]
926550002055	domain IV; other site
926550002056	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
926550002057	Topoisomerase C-terminal repeat; Region: Toprim_C_rpt; pfam13368
926550002058	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550002059	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550002060	active site
926550002061	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550002062	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
926550002063	Walker A/P-loop; other site
926550002064	ATP binding site [chemical binding]; other site
926550002065	Q-loop/lid; other site
926550002066	ABC transporter signature motif; other site
926550002067	Walker B; other site
926550002068	D-loop; other site
926550002069	H-loop/switch region; other site
926550002070	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550002071	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550002072	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550002073	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550002074	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550002075	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; pfam04230
926550002076	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
926550002077	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550002078	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
926550002079	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550002080	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550002081	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550002082	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
926550002083	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550002084	Winged helix-turn helix; Region: HTH_29; pfam13551
926550002085	Helix-turn-helix domain; Region: HTH_28; pfam13518
926550002086	Homeodomain-like domain; Region: HTH_32; pfam13565
926550002087	glycosyltransferase, TIGR04182 family; Region: glyco_TIGR04182
926550002088	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926550002089	Ligand binding site; other site
926550002090	Putative Catalytic site; other site
926550002091	DXD motif; other site
926550002092	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
926550002093	prephenate dehydrogenase; Validated; Region: PRK08507
926550002094	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
926550002095	Peptidase family M50; Region: Peptidase_M50; pfam02163
926550002096	active site
926550002097	putative substrate binding region [chemical binding]; other site
926550002098	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
926550002099	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
926550002100	NAD binding site [chemical binding]; other site
926550002101	homodimer interface [polypeptide binding]; other site
926550002102	active site
926550002103	substrate binding site [chemical binding]; other site
926550002104	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550002105	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550002106	TM-ABC transporter signature motif; other site
926550002107	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
926550002108	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550002109	Walker A/P-loop; other site
926550002110	ATP binding site [chemical binding]; other site
926550002111	Q-loop/lid; other site
926550002112	ABC transporter signature motif; other site
926550002113	Walker B; other site
926550002114	D-loop; other site
926550002115	H-loop/switch region; other site
926550002116	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550002117	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550002118	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550002119	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550002120	ligand binding site [chemical binding]; other site
926550002121	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550002122	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550002123	TM-ABC transporter signature motif; other site
926550002124	Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only]; Region: LCB5; COG1597
926550002125	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
926550002126	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
926550002127	active site
926550002128	substrate-binding site [chemical binding]; other site
926550002129	metal-binding site [ion binding]
926550002130	GTP binding site [chemical binding]; other site
926550002131	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
926550002132	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550002133	Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026
926550002134	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
926550002135	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
926550002136	Peptidase M16C associated; Region: M16C_assoc; pfam08367
926550002137	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
926550002138	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550002139	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550002140	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550002141	probable F420-dependent oxidoreductase, Rv3520c family; Region: F420_Rv3520c; TIGR03559
926550002142	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
926550002143	SCP-2 sterol transfer family; Region: SCP2; pfam02036
926550002144	Abhydrolase family; Region: Abhydrolase_7; pfam12715
926550002145	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550002146	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550002147	NAD(P) binding site [chemical binding]; other site
926550002148	active site
926550002149	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550002150	conserved repeat domain; Region: B_ant_repeat; TIGR01451
926550002151	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550002152	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550002153	Domain of unknown function DUF11; Region: DUF11; cl17728
926550002154	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
926550002155	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550002156	active site
926550002157	catalytic tetrad [active]
926550002158	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cd04332
926550002159	putative deacylase active site [active]
926550002160	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550002161	active site
926550002162	peptide chain release factor 1; Validated; Region: prfA; PRK00591
926550002163	This domain is found in peptide chain release factors; Region: PCRF; smart00937
926550002164	RF-1 domain; Region: RF-1; pfam00472
926550002165	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
926550002166	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550002167	S-adenosylmethionine binding site [chemical binding]; other site
926550002168	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550002169	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
926550002170	active site
926550002171	motif I; other site
926550002172	motif II; other site
926550002173	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550002174	Peptidase M1 family Aminopeptidase N; Region: M1_APN_4; cd09603
926550002175	Zn binding site [ion binding]; other site
926550002176	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
926550002177	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
926550002178	[4Fe-4S] binding site [ion binding]; other site
926550002179	molybdopterin cofactor binding site; other site
926550002180	This CD includes formate dehydrogenases (Fdh) H and N; nitrate reductases, Nap and Nas; and other related proteins. Formate dehydrogenase H is a component of the anaerobic formate hydrogen lyase complex  and catalyzes the reversible oxidation of formate...; Region: MopB_CT_Fdh-Nap-like; cd00508
926550002181	molybdopterin cofactor binding site; other site
926550002182	CHAT domain; Region: CHAT; pfam12770
926550002183	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002184	TPR motif; other site
926550002185	binding surface
926550002186	TPR repeat; Region: TPR_11; pfam13414
926550002187	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550002188	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550002189	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550002190	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550002191	active site
926550002192	catalytic residues [active]
926550002193	FAD binding domain; Region: FAD_binding_4; pfam01565
926550002194	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
926550002195	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
926550002196	FAD binding domain; Region: FAD_binding_4; pfam01565
926550002197	MG2 domain; Region: A2M_N; pfam01835
926550002198	MG2 domain; Region: A2M_N; pfam01835
926550002199	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
926550002200	Alpha-2-macroglobulin family; Region: A2M; pfam00207
926550002201	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926550002202	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
926550002203	surface patch; other site
926550002204	thioester region; other site
926550002205	A-macroglobulin complement component; Region: A2M_comp; pfam07678
926550002206	specificity defining residues; other site
926550002207	A-macroglobulin receptor; Region: A2M_recep; pfam07677
926550002208	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
926550002209	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550002210	ATP binding site [chemical binding]; other site
926550002211	Mg2+ binding site [ion binding]; other site
926550002212	G-X-G motif; other site
926550002213	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
926550002214	ATP binding site [chemical binding]; other site
926550002215	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
926550002216	Ubiquitin-like proteins; Region: UBQ; cl00155
926550002217	charged pocket; other site
926550002218	hydrophobic patch; other site
926550002219	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
926550002220	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
926550002221	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
926550002222	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
926550002223	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
926550002224	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
926550002225	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
926550002226	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
926550002227	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
926550002228	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
926550002229	active site
926550002230	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926550002231	Metallopeptidase family M24; Region: Peptidase_M24; pfam00557
926550002232	active site
926550002233	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
926550002234	RibD C-terminal domain; Region: RibD_C; cl17279
926550002235	TPR repeat; Region: TPR_11; pfam13414
926550002236	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002237	binding surface
926550002238	TPR motif; other site
926550002239	TPR repeat; Region: TPR_11; pfam13414
926550002240	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002241	binding surface
926550002242	TPR motif; other site
926550002243	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
926550002244	transmembrane helices; other site
926550002245	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
926550002246	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002247	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002248	binding surface
926550002249	TPR motif; other site
926550002250	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002251	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002252	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002253	binding surface
926550002254	TPR motif; other site
926550002255	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002256	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
926550002257	oligomerisation interface [polypeptide binding]; other site
926550002258	mobile loop; other site
926550002259	roof hairpin; other site
926550002260	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
926550002261	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
926550002262	ring oligomerisation interface [polypeptide binding]; other site
926550002263	ATP/Mg binding site [chemical binding]; other site
926550002264	stacking interactions; other site
926550002265	hinge regions; other site
926550002266	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
926550002267	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
926550002268	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
926550002269	active site
926550002270	multimer interface [polypeptide binding]; other site
926550002271	TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FcbT1; COG4663
926550002272	Bacterial extracellular solute-binding protein, family 7; Region: SBP_bac_7; cl15441
926550002273	TRAP-type mannitol/chloroaromatic compound transport system, large permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FcbT3; COG4664
926550002274	DctM-like transporters; Region: DctM; pfam06808
926550002275	Tripartite ATP-independent periplasmic transporters, DctQ component; Region: DctQ; cl01181
926550002276	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550002277	Fasciclin domain; Region: Fasciclin; pfam02469
926550002278	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550002279	Fasciclin domain; Region: Fasciclin; pfam02469
926550002280	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550002281	Fasciclin domain; Region: Fasciclin; pfam02469
926550002282	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550002283	Fasciclin domain; Region: Fasciclin; pfam02469
926550002284	Methyltransferase domain; Region: Methyltransf_26; pfam13659
926550002285	DNA modification methylase [DNA replication, recombination, and repair]; Region: COG0863
926550002286	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550002287	S-adenosylmethionine binding site [chemical binding]; other site
926550002288	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
926550002289	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
926550002290	dimer interface [polypeptide binding]; other site
926550002291	active site
926550002292	CoA binding pocket [chemical binding]; other site
926550002293	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
926550002294	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
926550002295	dimer interface [polypeptide binding]; other site
926550002296	active site
926550002297	CT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_1; cd04870
926550002298	ACT domains found N-terminal of phosphoserine phosphatase (PSP, SerB); Region: ACT_PSP_2; cd04871
926550002299	phosphoserine phosphatase SerB; Region: serB; TIGR00338
926550002300	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550002301	motif II; other site
926550002302	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550002303	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
926550002304	putative N- and C-terminal domain interface [polypeptide binding]; other site
926550002305	putative active site [active]
926550002306	MgATP binding site [chemical binding]; other site
926550002307	catalytic site [active]
926550002308	metal binding site [ion binding]; metal-binding site
926550002309	putative xylulose binding site [chemical binding]; other site
926550002310	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550002311	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002312	dimer interface [polypeptide binding]; other site
926550002313	conserved gate region; other site
926550002314	putative PBP binding loops; other site
926550002315	ABC-ATPase subunit interface; other site
926550002316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550002317	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002318	putative PBP binding loops; other site
926550002319	dimer interface [polypeptide binding]; other site
926550002320	ABC-ATPase subunit interface; other site
926550002321	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550002322	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550002323	hypothetical protein; Provisional; Region: PRK02947
926550002324	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926550002325	putative active site [active]
926550002326	ncharacterized protein conserved in bacteria [Function unknown]; Region: SpoIIIAA; COG3854
926550002327	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550002328	Walker A motif; other site
926550002329	ATP binding site [chemical binding]; other site
926550002330	Walker B motif; other site
926550002331	R3H domain. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine and histidine residues. R3H domains are found in proteins together with ATPase domains, SF1 helicase domains, SF2 DEAH helicase domains, Cys-rich...; Region: R3H; cl00297
926550002332	RxxxH motif; other site
926550002333	thymidylate kinase; Validated; Region: tmk; PRK00698
926550002334	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
926550002335	TMP-binding site; other site
926550002336	ATP-binding site [chemical binding]; other site
926550002337	Protein of unknown function (DUF970); Region: DUF970; cl17525
926550002338	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; cl00993
926550002339	Guanylate kinase; Region: Guanylate_kin; pfam00625
926550002340	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
926550002341	catalytic site [active]
926550002342	G-X2-G-X-G-K; other site
926550002343	Rhomboid family; Region: Rhomboid; pfam01694
926550002344	4-alpha-glucanotransferase; Provisional; Region: PRK14508
926550002345	Phospholipid methyltransferase; Region: PEMT; cl17370
926550002346	YhhN-like protein; Region: YhhN; pfam07947
926550002347	Predicted acyl esterases [General function prediction only]; Region: COG2936
926550002348	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
926550002349	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
926550002350	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926550002351	tetramer interface [polypeptide binding]; other site
926550002352	active site
926550002353	trigger factor; Region: tig; TIGR00115
926550002354	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
926550002355	Clp protease; Region: CLP_protease; pfam00574
926550002356	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
926550002357	oligomer interface [polypeptide binding]; other site
926550002358	active site residues [active]
926550002359	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
926550002360	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
926550002361	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
926550002362	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550002363	Walker A motif; other site
926550002364	ATP binding site [chemical binding]; other site
926550002365	Walker B motif; other site
926550002366	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
926550002367	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550002368	glycosyltransferase, MSMEG_0565 family; Region: MSMEG_0565_glyc; TIGR04047
926550002369	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550002370	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550002371	Ligand Binding Site [chemical binding]; other site
926550002372	putative glucosyl-3-phosphoglycerate synthase; Provisional; Region: PRK13915
926550002373	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926550002374	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550002375	catalytic core [active]
926550002376	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
926550002377	Trehalase; Region: Trehalase; cl17346
926550002378	A/G-specific DNA glycosylase [DNA replication, recombination, and repair]; Region: MutY; COG1194
926550002379	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926550002380	minor groove reading motif; other site
926550002381	helix-hairpin-helix signature motif; other site
926550002382	substrate binding pocket [chemical binding]; other site
926550002383	active site
926550002384	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; pfam10576
926550002385	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
926550002386	active site
926550002387	8-oxo-dGMP binding site [chemical binding]; other site
926550002388	nudix motif; other site
926550002389	metal binding site [ion binding]; metal-binding site
926550002390	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926550002391	4Fe-4S binding domain; Region: Fer4; cl02805
926550002392	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926550002393	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926550002394	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926550002395	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926550002396	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926550002397	Cysteine-rich domain; Region: CCG; pfam02754
926550002398	Cysteine-rich domain; Region: CCG; pfam02754
926550002399	Bacteriocin-protection, YdeI or OmpD-Associated; Region: OmdA; pfam13376
926550002400	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
926550002401	MgtE intracellular N domain; Region: MgtE_N; pfam03448
926550002402	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
926550002403	Divalent cation transporter; Region: MgtE; pfam01769
926550002404	PUCC protein; Region: PUCC; pfam03209
926550002405	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
926550002406	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
926550002407	Catalytic site [active]
926550002408	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
926550002409	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
926550002410	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550002411	enoyl-CoA hydratase; Provisional; Region: PRK05862
926550002412	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926550002413	substrate binding site [chemical binding]; other site
926550002414	oxyanion hole (OAH) forming residues; other site
926550002415	trimer interface [polypeptide binding]; other site
926550002416	Domain of unknown function (DUF4037); Region: DUF4037; pfam13228
926550002417	peptidase; Reviewed; Region: PRK13004
926550002418	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
926550002419	putative metal binding site [ion binding]; other site
926550002420	putative dimer interface [polypeptide binding]; other site
926550002421	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
926550002422	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550002423	active site
926550002424	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
926550002425	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
926550002426	nitrous-oxide reductase, Sec-dependent; Region: nitrous_NosZ_Gp; TIGR04246
926550002427	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926550002428	nitrous oxide reductase family maturation protein NosD; Region: NosD_copper_fam; TIGR04247
926550002429	parallel beta-helix repeat (two copies); Region: para_beta_helix; TIGR03804
926550002430	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550002431	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
926550002432	Walker A/P-loop; other site
926550002433	ATP binding site [chemical binding]; other site
926550002434	Q-loop/lid; other site
926550002435	ABC transporter signature motif; other site
926550002436	Walker B; other site
926550002437	D-loop; other site
926550002438	H-loop/switch region; other site
926550002439	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
926550002440	NosL; Region: NosL; cl01769
926550002441	putative heme-binding domain, Pirellula/Verrucomicrobium type; Region: CxxCH_TIGR02603
926550002442	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
926550002443	Cupin domain; Region: Cupin_2; pfam07883
926550002444	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
926550002445	heme-binding site [chemical binding]; other site
926550002446	Ubiquitin-like proteins; Region: UBQ; cl00155
926550002447	charged pocket; other site
926550002448	hydrophobic patch; other site
926550002449	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
926550002450	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550002451	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550002452	ligand binding site [chemical binding]; other site
926550002453	flexible hinge region; other site
926550002454	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926550002455	putative switch regulator; other site
926550002456	non-specific DNA interactions [nucleotide binding]; other site
926550002457	DNA binding site [nucleotide binding]
926550002458	sequence specific DNA binding site [nucleotide binding]; other site
926550002459	putative cAMP binding site [chemical binding]; other site
926550002460	Aldose 1-epimerase, similar to Escherichia coli c4013; Region: Aldose_epim_Ec_c4013; cd09023
926550002461	active site
926550002462	catalytic residues [active]
926550002463	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550002464	putative substrate translocation pore; other site
926550002465	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
926550002466	bifunctional shikimate kinase/3-dehydroquinate synthase; Provisional; Region: PRK14021
926550002467	ADP binding site [chemical binding]; other site
926550002468	magnesium binding site [ion binding]; other site
926550002469	putative shikimate binding site; other site
926550002470	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
926550002471	active site
926550002472	dimer interface [polypeptide binding]; other site
926550002473	metal binding site [ion binding]; metal-binding site
926550002474	AAA domain; Region: AAA_33; pfam13671
926550002475	AAA domain; Region: AAA_17; cl17253
926550002476	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
926550002477	chorismate synthase; Validated; Region: PRK05382
926550002478	Tetramer interface [polypeptide binding]; other site
926550002479	active site
926550002480	FMN-binding site [chemical binding]; other site
926550002481	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
926550002482	Clp amino terminal domain; Region: Clp_N; pfam02861
926550002483	Clp amino terminal domain; Region: Clp_N; pfam02861
926550002484	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550002485	Walker A motif; other site
926550002486	ATP binding site [chemical binding]; other site
926550002487	Walker B motif; other site
926550002488	arginine finger; other site
926550002489	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550002490	Walker A motif; other site
926550002491	ATP binding site [chemical binding]; other site
926550002492	Walker B motif; other site
926550002493	arginine finger; other site
926550002494	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
926550002495	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550002496	Coenzyme A binding pocket [chemical binding]; other site
926550002497	chaperone protein DnaJ; Provisional; Region: PRK14299
926550002498	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926550002499	HSP70 interaction site [polypeptide binding]; other site
926550002500	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
926550002501	substrate binding site [polypeptide binding]; other site
926550002502	dimer interface [polypeptide binding]; other site
926550002503	GrpE; Region: GrpE; pfam01025
926550002504	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
926550002505	dimer interface [polypeptide binding]; other site
926550002506	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
926550002507	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
926550002508	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
926550002509	nucleotide binding site [chemical binding]; other site
926550002510	NEF interaction site [polypeptide binding]; other site
926550002511	SBD interface [polypeptide binding]; other site
926550002512	LabA_like proteins; Region: LabA_like/DUF88; cl10034
926550002513	Uncharacterized conserved protein [Function unknown]; Region: COG1432
926550002514	putative metal binding site [ion binding]; other site
926550002515	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550002516	D-mannonate oxidoreductase; Provisional; Region: PRK08277
926550002517	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550002518	NAD(P) binding site [chemical binding]; other site
926550002519	active site
926550002520	Acylphosphatase; Region: Acylphosphatase; pfam00708
926550002521	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
926550002522	HypF finger; Region: zf-HYPF; pfam07503
926550002523	HypF finger; Region: zf-HYPF; pfam07503
926550002524	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
926550002525	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550002526	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550002527	S-adenosylmethionine binding site [chemical binding]; other site
926550002528	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
926550002529	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
926550002530	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
926550002531	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550002532	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
926550002533	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550002534	DNA binding residues [nucleotide binding]
926550002535	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550002536	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550002537	The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin.  Chitin is degraded by a two step process: i)...; Region: GH20_chitobiase-like; cd06563
926550002538	Glycosyl hydrolase family 20, catalytic domain; Region: Glyco_hydro_20; pfam00728
926550002539	active site
926550002540	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
926550002541	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
926550002542	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
926550002543	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
926550002544	lipoyl attachment site [posttranslational modification]; other site
926550002545	methyltransferase, FkbM family; Region: fkbM_fam; TIGR01444
926550002546	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
926550002547	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550002548	YceI-like domain; Region: YceI; pfam04264
926550002549	Sulfatase; Region: Sulfatase; cl17466
926550002550	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550002551	uncharacterized ygcE-like proteins; Region: FGGY_ygcE_like; cd07779
926550002552	putative N- and C-terminal domain interface [polypeptide binding]; other site
926550002553	putative active site [active]
926550002554	MgATP binding site [chemical binding]; other site
926550002555	catalytic site [active]
926550002556	metal binding site [ion binding]; metal-binding site
926550002557	putative carbohydrate binding site [chemical binding]; other site
926550002558	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550002559	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550002560	active site
926550002561	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
926550002562	polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or...; Region: PKS; cd00833
926550002563	active site
926550002564	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
926550002565	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
926550002566	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
926550002567	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
926550002568	active site
926550002569	ketoreductase (KR), subgroup 2, complex (x) SDRs; Region: KR_2_SDR_x; cd08953
926550002570	This enzymatic domain is part of bacterial polyketide synthases; Region: PKS_KR; smart00822
926550002571	putative NADP binding site [chemical binding]; other site
926550002572	active site
926550002573	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
926550002574	putative active site [active]
926550002575	homotetrameric interface [polypeptide binding]; other site
926550002576	metal binding site [ion binding]; metal-binding site
926550002577	Antitoxin of toxin-antitoxin stability system N-terminal; Region: RelB_N; pfam12910
926550002578	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
926550002579	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
926550002580	Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism]; Region: COG4799
926550002581	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
926550002582	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
926550002583	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
926550002584	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926550002585	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550002586	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
926550002587	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926550002588	carboxyltransferase (CT) interaction site; other site
926550002589	biotinylation site [posttranslational modification]; other site
926550002590	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550002591	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550002592	Walker A/P-loop; other site
926550002593	ATP binding site [chemical binding]; other site
926550002594	Q-loop/lid; other site
926550002595	ABC transporter signature motif; other site
926550002596	Walker B; other site
926550002597	D-loop; other site
926550002598	H-loop/switch region; other site
926550002599	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550002600	ATP-binding cassette domain of the lipid transporters, subfamily A; Region: ABC_subfamily_A; cd03263
926550002601	Walker A/P-loop; other site
926550002602	ATP binding site [chemical binding]; other site
926550002603	Q-loop/lid; other site
926550002604	ABC transporter signature motif; other site
926550002605	Walker B; other site
926550002606	D-loop; other site
926550002607	H-loop/switch region; other site
926550002608	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
926550002609	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550002610	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
926550002611	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926550002612	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926550002613	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550002614	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550002615	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
926550002616	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
926550002617	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
926550002618	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
926550002619	Beta galactosidase small chain; Region: Bgal_small_N; smart01038
926550002620	Gluconate kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_GntK; cd07770
926550002621	N- and C-terminal domain interface [polypeptide binding]; other site
926550002622	D-xylulose kinase; Region: XylB; TIGR01312
926550002623	active site
926550002624	catalytic site [active]
926550002625	metal binding site [ion binding]; metal-binding site
926550002626	carbohydrate binding site [chemical binding]; other site
926550002627	ATP binding site [chemical binding]; other site
926550002628	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926550002629	Trp docking motif [polypeptide binding]; other site
926550002630	PQQ-like domain; Region: PQQ_2; pfam13360
926550002631	active site
926550002632	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
926550002633	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550002634	Zn2+ binding site [ion binding]; other site
926550002635	Mg2+ binding site [ion binding]; other site
926550002636	PAS fold; Region: PAS_4; pfam08448
926550002637	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550002638	PAS fold; Region: PAS_3; pfam08447
926550002639	putative active site [active]
926550002640	heme pocket [chemical binding]; other site
926550002641	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550002642	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain); Region: PAC; smart00086
926550002643	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550002644	dimer interface [polypeptide binding]; other site
926550002645	phosphorylation site [posttranslational modification]
926550002646	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550002647	ATP binding site [chemical binding]; other site
926550002648	Mg2+ binding site [ion binding]; other site
926550002649	G-X-G motif; other site
926550002650	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
926550002651	Uncharacterized protein related to plant photosystem II stability/assembly factor [General function prediction only]; Region: COG4447
926550002652	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
926550002653	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
926550002654	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
926550002655	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550002656	AAA ATPase domain; Region: AAA_16; pfam13191
926550002657	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002658	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002659	binding surface
926550002660	TPR motif; other site
926550002661	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550002662	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002663	binding surface
926550002664	TPR motif; other site
926550002665	TPR repeat; Region: TPR_11; pfam13414
926550002666	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550002667	type VII secretion-associated serine protease mycosin; Region: T7SS_mycosin; TIGR03921
926550002668	active site
926550002669	catalytic residues [active]
926550002670	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
926550002671	MPT binding site; other site
926550002672	trimer interface [polypeptide binding]; other site
926550002673	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
926550002674	L-lactate permease; Region: Lactate_perm; cl00701
926550002675	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
926550002676	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
926550002677	VanW like protein; Region: VanW; pfam04294
926550002678	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
926550002679	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
926550002680	active site
926550002681	HIGH motif; other site
926550002682	KMSKS motif; other site
926550002683	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
926550002684	tRNA binding surface [nucleotide binding]; other site
926550002685	anticodon binding site; other site
926550002686	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
926550002687	classical (c) SDRs; Region: SDR_c; cd05233
926550002688	NAD(P) binding site [chemical binding]; other site
926550002689	active site
926550002690	uncharacterized cyanobacterial protein, TIGR03792 family; Region: TIGR03792
926550002691	probable F420-dependent oxidoreductase, Rv3093c family; Region: F420_Rv3093c; TIGR03841
926550002692	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
926550002693	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926550002694	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
926550002695	NAD binding site [chemical binding]; other site
926550002696	PHB/PHA accumulation regulator DNA-binding domain; Region: PHB_acc_N; pfam07879
926550002697	Poly(hydroxyalcanoate) granule associated protein (phasin); Region: Phasin; cl07863
926550002698	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926550002699	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
926550002700	active site
926550002701	nucleophile elbow; other site
926550002702	Glycosyl hydrolase catalytic core; Region: Glyco_hydro_cc; pfam11790
926550002703	EDD domain protein, DegV family; Region: DegV; TIGR00762
926550002704	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
926550002705	putative phosphate acyltransferase; Provisional; Region: PRK05331
926550002706	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
926550002707	hypothetical protein; Reviewed; Region: PRK00024
926550002708	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
926550002709	MPN+ (JAMM) motif; other site
926550002710	Zinc-binding site [ion binding]; other site
926550002711	RDD family; Region: RDD; pfam06271
926550002712	Uncharacterized membrane protein [Function unknown]; Region: SpoIIM; COG1300
926550002713	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
926550002714	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
926550002715	Switch I; other site
926550002716	Switch II; other site
926550002717	septum formation inhibitor; Reviewed; Region: minC; PRK00513
926550002718	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
926550002719	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926550002720	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926550002721	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926550002722	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
926550002723	rod shape-determining protein MreC; Provisional; Region: PRK13922
926550002724	rod shape-determining protein MreC; Region: MreC; pfam04085
926550002725	rod shape-determining protein MreB; Provisional; Region: PRK13927
926550002726	MreB and similar proteins; Region: MreB_like; cd10225
926550002727	nucleotide binding site [chemical binding]; other site
926550002728	Mg binding site [ion binding]; other site
926550002729	putative protofilament interaction site [polypeptide binding]; other site
926550002730	RodZ interaction site [polypeptide binding]; other site
926550002731	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
926550002732	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
926550002733	TilS substrate C-terminal domain; Region: TilS_C; smart00977
926550002734	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
926550002735	putative deacylase active site [active]
926550002736	zinc-ribbon domain; Region: zf-ribbon_3; cl11198
926550002737	Double zinc ribbon; Region: DZR; pfam12773
926550002738	lysine-arginine-ornithine-binding periplasmic protein; Region: 3A0103s03R; TIGR01096
926550002739	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550002740	substrate binding pocket [chemical binding]; other site
926550002741	membrane-bound complex binding site; other site
926550002742	hinge residues; other site
926550002743	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
926550002744	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002745	conserved gate region; other site
926550002746	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
926550002747	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002748	dimer interface [polypeptide binding]; other site
926550002749	conserved gate region; other site
926550002750	putative PBP binding loops; other site
926550002751	ABC-ATPase subunit interface; other site
926550002752	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
926550002753	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002754	dimer interface [polypeptide binding]; other site
926550002755	conserved gate region; other site
926550002756	putative PBP binding loops; other site
926550002757	ABC-ATPase subunit interface; other site
926550002758	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
926550002759	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
926550002760	Walker A/P-loop; other site
926550002761	ATP binding site [chemical binding]; other site
926550002762	Q-loop/lid; other site
926550002763	ABC transporter signature motif; other site
926550002764	Walker B; other site
926550002765	D-loop; other site
926550002766	H-loop/switch region; other site
926550002767	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550002768	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
926550002769	Ketopantoate reductase [Coenzyme metabolism]; Region: ApbA; COG1893
926550002770	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
926550002771	sn-glycerol-3-phosphate dehydrogenase subunit C; Provisional; Region: glpC; PRK11168
926550002772	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926550002773	Cysteine-rich domain; Region: CCG; pfam02754
926550002774	Cysteine-rich domain; Region: CCG; pfam02754
926550002775	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
926550002776	FAD binding domain; Region: FAD_binding_2; pfam00890
926550002777	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926550002778	glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; Region: glycerol3P_GlpA; TIGR03377
926550002779	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
926550002780	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
926550002781	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
926550002782	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
926550002783	dimerization domain swap beta strand [polypeptide binding]; other site
926550002784	regulatory protein interface [polypeptide binding]; other site
926550002785	active site
926550002786	regulatory phosphorylation site [posttranslational modification]; other site
926550002787	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
926550002788	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
926550002789	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926550002790	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926550002791	glycerol kinase; Provisional; Region: glpK; PRK00047
926550002792	Cellulomonas sp. glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CsGK_like; cd07789
926550002793	N- and C-terminal domain interface [polypeptide binding]; other site
926550002794	putative homotetramer interface [polypeptide binding]; other site
926550002795	active site
926550002796	glycerol binding site [chemical binding]; other site
926550002797	MgATP binding site [chemical binding]; other site
926550002798	homodimer interface [polypeptide binding]; other site
926550002799	DAK2 domain; Region: Dak2; cl03685
926550002800	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
926550002801	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
926550002802	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
926550002803	active site
926550002804	dimerization interface [polypeptide binding]; other site
926550002805	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
926550002806	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
926550002807	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550002808	active site
926550002809	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
926550002810	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
926550002811	dimer interface [polypeptide binding]; other site
926550002812	catalytic triad [active]
926550002813	peroxidatic and resolving cysteines [active]
926550002814	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550002815	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926550002816	Walker A motif; other site
926550002817	ATP binding site [chemical binding]; other site
926550002818	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550002819	AAA ATPase domain; Region: AAA_16; pfam13191
926550002820	Walker A motif; other site
926550002821	ATP binding site [chemical binding]; other site
926550002822	Walker B motif; other site
926550002823	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550002824	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926550002825	Amidase; Region: Amidase; cl11426
926550002826	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
926550002827	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
926550002828	NAD(P) binding pocket [chemical binding]; other site
926550002829	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
926550002830	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926550002831	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926550002832	protein binding site [polypeptide binding]; other site
926550002833	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550002834	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550002835	active site
926550002836	phosphorylation site [posttranslational modification]
926550002837	intermolecular recognition site; other site
926550002838	dimerization interface [polypeptide binding]; other site
926550002839	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550002840	DNA binding residues [nucleotide binding]
926550002841	dimerization interface [polypeptide binding]; other site
926550002842	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550002843	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550002844	ATP binding site [chemical binding]; other site
926550002845	Mg2+ binding site [ion binding]; other site
926550002846	G-X-G motif; other site
926550002847	putative regulatory protein, FmdB family; Region: CxxC_CxxC_SSSS; TIGR02605
926550002848	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
926550002849	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550002850	active site
926550002851	Predicted membrane protein [Function unknown]; Region: COG1950
926550002852	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
926550002853	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
926550002854	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
926550002855	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
926550002856	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
926550002857	ligand binding site [chemical binding]; other site
926550002858	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550002859	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550002860	TM-ABC transporter signature motif; other site
926550002861	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550002862	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550002863	TM-ABC transporter signature motif; other site
926550002864	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
926550002865	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550002866	Walker A/P-loop; other site
926550002867	ATP binding site [chemical binding]; other site
926550002868	Q-loop/lid; other site
926550002869	ABC transporter signature motif; other site
926550002870	Walker B; other site
926550002871	D-loop; other site
926550002872	H-loop/switch region; other site
926550002873	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550002874	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
926550002875	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII; cd09992
926550002876	active site
926550002877	Zn binding site [ion binding]; other site
926550002878	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926550002879	binding surface
926550002880	TPR motif; other site
926550002881	Homeodomain-like domain; Region: HTH_23; pfam13384
926550002882	Winged helix-turn helix; Region: HTH_29; pfam13551
926550002883	Homeodomain-like domain; Region: HTH_32; pfam13565
926550002884	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550002885	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
926550002886	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
926550002887	active site
926550002888	multimer interface [polypeptide binding]; other site
926550002889	SnoaL-like domain; Region: SnoaL_2; pfam12680
926550002890	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550002891	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550002892	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550002893	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926550002894	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
926550002895	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002896	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
926550002897	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002898	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
926550002899	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
926550002900	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002901	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
926550002902	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
926550002903	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
926550002904	NADH-quinone oxidoreductase, chain I; Region: NuoI; TIGR01971
926550002905	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926550002906	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
926550002907	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
926550002908	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
926550002909	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550002910	catalytic loop [active]
926550002911	iron binding site [ion binding]; other site
926550002912	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
926550002913	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550002914	molybdopterin cofactor binding site; other site
926550002915	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
926550002916	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
926550002917	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
926550002918	putative dimer interface [polypeptide binding]; other site
926550002919	[2Fe-2S] cluster binding site [ion binding]; other site
926550002920	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
926550002921	SLBB domain; Region: SLBB; pfam10531
926550002922	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
926550002923	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
926550002924	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926550002925	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
926550002926	NADH dehydrogenase subunit D; Validated; Region: PRK06075
926550002927	NADH dehydrogenase subunit B; Validated; Region: PRK06411
926550002928	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
926550002929	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
926550002930	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
926550002931	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
926550002932	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
926550002933	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
926550002934	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
926550002935	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
926550002936	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002937	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
926550002938	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002939	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
926550002940	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550002941	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550002942	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550002943	DNA binding site [nucleotide binding]
926550002944	domain linker motif; other site
926550002945	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550002946	ligand binding site [chemical binding]; other site
926550002947	dimerization interface [polypeptide binding]; other site
926550002948	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550002949	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550002950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002951	dimer interface [polypeptide binding]; other site
926550002952	conserved gate region; other site
926550002953	putative PBP binding loops; other site
926550002954	ABC-ATPase subunit interface; other site
926550002955	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550002956	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550002957	dimer interface [polypeptide binding]; other site
926550002958	conserved gate region; other site
926550002959	putative PBP binding loops; other site
926550002960	ABC-ATPase subunit interface; other site
926550002961	PQQ-like domain; Region: PQQ_2; pfam13360
926550002962	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
926550002963	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926550002964	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926550002965	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926550002966	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
926550002967	active site
926550002968	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
926550002969	Enolase-superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion; Region: enolase_like; cl17188
926550002970	metal binding site [ion binding]; metal-binding site
926550002971	substrate binding pocket [chemical binding]; other site
926550002972	alpha-galactosidase; Provisional; Region: PRK15076
926550002973	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
926550002974	NAD binding site [chemical binding]; other site
926550002975	sugar binding site [chemical binding]; other site
926550002976	divalent metal binding site [ion binding]; other site
926550002977	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550002978	dimer interface [polypeptide binding]; other site
926550002979	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
926550002980	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
926550002981	NAD(P) binding site [chemical binding]; other site
926550002982	LDH/MDH dimer interface [polypeptide binding]; other site
926550002983	substrate binding site [chemical binding]; other site
926550002984	Ion channel; Region: Ion_trans_2; pfam07885
926550002985	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
926550002986	TrkA-N domain; Region: TrkA_N; pfam02254
926550002987	TrkA-C domain; Region: TrkA_C; pfam02080
926550002988	TrkA-N domain; Region: TrkA_N; pfam02254
926550002989	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
926550002990	TrkA-C domain; Region: TrkA_C; pfam02080
926550002991	methylthioribose kinase; Reviewed; Region: mtnK; PRK09550
926550002992	Phosphotransferase enzyme family; Region: APH; pfam01636
926550002993	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
926550002994	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182
926550002995	K+-dependent Na+/Ca+ exchanger related-protein; Region: TIGR00367
926550002996	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
926550002997	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
926550002998	K+-dependent Na+/Ca+ exchanger related-protein; Region: TIGR00367
926550002999	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
926550003000	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
926550003001	purine nucleoside phosphorylase; Provisional; Region: PRK08202
926550003002	gamma-glutamyl kinase; Provisional; Region: PRK05429
926550003003	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
926550003004	nucleotide binding site [chemical binding]; other site
926550003005	homotetrameric interface [polypeptide binding]; other site
926550003006	putative phosphate binding site [ion binding]; other site
926550003007	putative allosteric binding site; other site
926550003008	PUA domain; Region: PUA; pfam01472
926550003009	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
926550003010	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
926550003011	Walker A/P-loop; other site
926550003012	ATP binding site [chemical binding]; other site
926550003013	Q-loop/lid; other site
926550003014	ABC transporter signature motif; other site
926550003015	Walker B; other site
926550003016	D-loop; other site
926550003017	H-loop/switch region; other site
926550003018	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
926550003019	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
926550003020	Walker A/P-loop; other site
926550003021	ATP binding site [chemical binding]; other site
926550003022	Q-loop/lid; other site
926550003023	ABC transporter signature motif; other site
926550003024	Walker B; other site
926550003025	D-loop; other site
926550003026	H-loop/switch region; other site
926550003027	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
926550003028	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
926550003029	Peptidase M20 acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase (ArgE/DapE)-like; Region: M20_ArgE_DapE_like; cd08659
926550003030	metal binding site [ion binding]; metal-binding site
926550003031	dimer interface [polypeptide binding]; other site
926550003032	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
926550003033	putative active site pocket [active]
926550003034	cleavage site
926550003035	Predicted membrane protein [Function unknown]; Region: COG4684
926550003036	hypothetical protein; Provisional; Region: PRK08201
926550003037	Uncharacterized M20 Dipeptidases; Region: M20_dipept_like_3; cd05680
926550003038	metal binding site [ion binding]; metal-binding site
926550003039	putative dimer interface [polypeptide binding]; other site
926550003040	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550003041	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550003042	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550003043	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550003044	dimer interface [polypeptide binding]; other site
926550003045	phosphorylation site [posttranslational modification]
926550003046	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550003047	ATP binding site [chemical binding]; other site
926550003048	Mg2+ binding site [ion binding]; other site
926550003049	G-X-G motif; other site
926550003050	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003051	Walker A motif; other site
926550003052	ATP binding site [chemical binding]; other site
926550003053	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550003054	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
926550003055	Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins; Region: SRPBCC_6; cd07824
926550003056	putative hydrophobic ligand binding site [chemical binding]; other site
926550003057	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550003058	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550003059	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
926550003060	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
926550003061	Uncharacterized conserved protein [Function unknown]; Region: COG1359
926550003062	DinB superfamily; Region: DinB_2; pfam12867
926550003063	SnoaL-like domain; Region: SnoaL_2; pfam12680
926550003064	3-oxoadipate enol-lactonase; Region: protocat_pcaD; TIGR02427
926550003065	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
926550003066	CoA binding domain; Region: CoA_binding_2; pfam13380
926550003067	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
926550003068	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
926550003069	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926550003070	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550003071	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926550003072	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550003073	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550003074	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550003075	Histidine phosphatase superfamily (branch 1); Region: His_Phos_1; pfam00300
926550003076	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550003077	aspartate aminotransferase; Provisional; Region: PRK05764
926550003078	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550003079	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550003080	homodimer interface [polypeptide binding]; other site
926550003081	catalytic residue [active]
926550003082	Proline dehydrogenase; Region: Pro_dh; cl03282
926550003083	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
926550003084	DEAD/DEAH box helicase; Region: DEAD; pfam00270
926550003085	ATP binding site [chemical binding]; other site
926550003086	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
926550003087	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003088	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550003089	Fasciclin domain; Region: Fasciclin; pfam02469
926550003090	Transglycosylase; Region: Transgly; pfam00912
926550003091	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
926550003092	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
926550003093	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
926550003094	DNA binding site [nucleotide binding]
926550003095	active site
926550003096	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550003097	Coenzyme A binding pocket [chemical binding]; other site
926550003098	Cupin domain; Region: Cupin_2; pfam07883
926550003099	AAA ATPase domain; Region: AAA_16; pfam13191
926550003100	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550003101	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550003102	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550003103	DNA binding residues [nucleotide binding]
926550003104	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
926550003105	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
926550003106	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926550003107	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926550003108	NAD(P) binding site [chemical binding]; other site
926550003109	catalytic residues [active]
926550003110	homoserine dehydrogenase family protein; Region: PLN02700
926550003111	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
926550003112	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
926550003113	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
926550003114	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926550003115	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
926550003116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003117	Walker A motif; other site
926550003118	ATP binding site [chemical binding]; other site
926550003119	Walker B motif; other site
926550003120	Peptidase family M41; Region: Peptidase_M41; pfam01434
926550003121	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
926550003122	Protein of unknown function (DUF664); Region: DUF664; pfam04978
926550003123	DinB superfamily; Region: DinB_2; pfam12867
926550003124	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
926550003125	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
926550003126	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
926550003127	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
926550003128	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
926550003129	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
926550003130	PHP family phosphoesterase with a Zn ribbon [General function prediction only]; Region: COG1379
926550003131	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
926550003132	Part of AAA domain; Region: AAA_19; pfam13245
926550003133	Family description; Region: UvrD_C_2; pfam13538
926550003134	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
926550003135	structural tetrad; other site
926550003136	FOG: WD40 repeat [General function prediction only]; Region: COG2319
926550003137	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
926550003138	structural tetrad; other site
926550003139	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926550003140	SIR2-like domain; Region: SIR2_2; pfam13289
926550003141	CHAT domain; Region: CHAT; pfam12770
926550003142	Uncharacterized conserved protein [Function unknown]; Region: COG1262
926550003143	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
926550003144	ABC-type uncharacterized transport system; Region: ABC_transp_aux; pfam09822
926550003145	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
926550003146	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
926550003147	tandem repeat interface [polypeptide binding]; other site
926550003148	oligomer interface [polypeptide binding]; other site
926550003149	active site residues [active]
926550003150	A subgroup of the band 7 domain of flotillin (reggie) like proteins. This subgroup contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual...; Region: Band_7_5; cd03408
926550003151	Helix-turn-helix domain; Region: HTH_17; pfam12728
926550003152	DNA directed RNA polymerase, 7 kDa subunit; Region: DNA_RNApol_7kD; cl00874
926550003153	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
926550003154	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
926550003155	Ycf1; Provisional; Region: ycf1; CHL00204
926550003156	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550003157	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926550003158	Ligand binding site; other site
926550003159	Putative Catalytic site; other site
926550003160	DXD motif; other site
926550003161	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550003162	active site
926550003163	phosphorylation site [posttranslational modification]
926550003164	intermolecular recognition site; other site
926550003165	dimerization interface [polypeptide binding]; other site
926550003166	ANTAR domain; Region: ANTAR; pfam03861
926550003167	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
926550003168	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
926550003169	Histidine kinase; Region: HisKA_2; pfam07568
926550003170	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550003171	ATP binding site [chemical binding]; other site
926550003172	Mg2+ binding site [ion binding]; other site
926550003173	G-X-G motif; other site
926550003174	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
926550003175	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
926550003176	putative active site [active]
926550003177	substrate binding site [chemical binding]; other site
926550003178	putative cosubstrate binding site; other site
926550003179	catalytic site [active]
926550003180	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
926550003181	substrate binding site [chemical binding]; other site
926550003182	Tic20-like protein; Region: Tic20; pfam09685
926550003183	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
926550003184	potential frameshift: common BLAST hit: gi|312143961|ref|YP_003995407.1| family 5 extracellular solute-binding protein
926550003185	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550003186	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003187	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550003188	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003189	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550003190	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003191	dimer interface [polypeptide binding]; other site
926550003192	conserved gate region; other site
926550003193	putative PBP binding loops; other site
926550003194	ABC-ATPase subunit interface; other site
926550003195	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550003196	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
926550003197	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003198	dimer interface [polypeptide binding]; other site
926550003199	conserved gate region; other site
926550003200	ABC-ATPase subunit interface; other site
926550003201	histone acetyltransferase, ELP3 family; Region: ELP3; TIGR01211
926550003202	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550003203	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
926550003204	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
926550003205	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550003206	catalytic loop [active]
926550003207	iron binding site [ion binding]; other site
926550003208	H+ Antiporter protein; Region: 2A0121; TIGR00900
926550003209	Domain of unknown function (DUF368); Region: DUF368; pfam04018
926550003210	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
926550003211	sucrose phosphorylase; Region: sucrose_gtfA; TIGR03852
926550003212	active site
926550003213	homodimer interface [polypeptide binding]; other site
926550003214	catalytic site [active]
926550003215	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
926550003216	DHH family; Region: DHH; pfam01368
926550003217	DHHA1 domain; Region: DHHA1; pfam02272
926550003218	Peptidase family M48; Region: Peptidase_M48; cl12018
926550003219	GTP-binding protein LepA; Provisional; Region: PRK05433
926550003220	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
926550003221	G1 box; other site
926550003222	putative GEF interaction site [polypeptide binding]; other site
926550003223	GTP/Mg2+ binding site [chemical binding]; other site
926550003224	Switch I region; other site
926550003225	G2 box; other site
926550003226	G3 box; other site
926550003227	Switch II region; other site
926550003228	G4 box; other site
926550003229	G5 box; other site
926550003230	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
926550003231	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
926550003232	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
926550003233	Ribosomal RNA adenine dimethylase; Region: RrnaAD; pfam00398
926550003234	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550003235	S-adenosylmethionine binding site [chemical binding]; other site
926550003236	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550003237	Ribonuclease D [Translation, ribosomal structure and biogenesis]; Region: Rnd; COG0349
926550003238	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
926550003239	catalytic site [active]
926550003240	putative active site [active]
926550003241	putative substrate binding site [chemical binding]; other site
926550003242	HRDC domain; Region: HRDC; pfam00570
926550003243	HRDC domain; Region: HRDC; pfam00570
926550003244	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
926550003245	PLD-like domain; Region: PLDc_2; pfam13091
926550003246	putative active site [active]
926550003247	catalytic site [active]
926550003248	PLD-like domain; Region: PLDc_2; pfam13091
926550003249	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
926550003250	putative active site [active]
926550003251	catalytic site [active]
926550003252	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
926550003253	malate synthase A; Region: malate_syn_A; TIGR01344
926550003254	active site
926550003255	Response regulator receiver domain; Region: Response_reg; pfam00072
926550003256	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550003257	active site
926550003258	phosphorylation site [posttranslational modification]
926550003259	intermolecular recognition site; other site
926550003260	dimerization interface [polypeptide binding]; other site
926550003261	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
926550003262	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550003263	PAS domain; Region: PAS_9; pfam13426
926550003264	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
926550003265	active site
926550003266	catalytic site [active]
926550003267	substrate binding site [chemical binding]; other site
926550003268	Response regulator receiver domain; Region: Response_reg; pfam00072
926550003269	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550003270	active site
926550003271	phosphorylation site [posttranslational modification]
926550003272	intermolecular recognition site; other site
926550003273	dimerization interface [polypeptide binding]; other site
926550003274	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
926550003275	Na binding site [ion binding]; other site
926550003276	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550003277	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550003278	dimer interface [polypeptide binding]; other site
926550003279	phosphorylation site [posttranslational modification]
926550003280	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550003281	ATP binding site [chemical binding]; other site
926550003282	Mg2+ binding site [ion binding]; other site
926550003283	G-X-G motif; other site
926550003284	Predicted signal-transduction protein containing cAMP-binding and CBS domains [Signal transduction mechanisms]; Region: COG2905
926550003285	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550003286	ligand binding site [chemical binding]; other site
926550003287	flexible hinge region; other site
926550003288	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with either the CAP_ED (cAMP receptor protein effector domain) family of transcription factors and the DUF294 domain or the PB1 (Phox and Bem1p) domain; Region: CBS_pair_CAP-ED_DUF294_PBI_assoc2; cd04800
926550003289	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
926550003290	metal binding triad; other site
926550003291	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
926550003292	Predicted symporter [General function prediction only]; Region: DhlC; COG4147
926550003293	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
926550003294	Na binding site [ion binding]; other site
926550003295	Domain of unknown function (DUF4212); Region: DUF4212; pfam13937
926550003296	acetyl-CoA synthetase; Provisional; Region: PRK00174
926550003297	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550003298	acyl-activating enzyme (AAE) consensus motif; other site
926550003299	AMP binding site [chemical binding]; other site
926550003300	active site
926550003301	CoA binding site [chemical binding]; other site
926550003302	acetyl-CoA synthetase; Provisional; Region: PRK00174
926550003303	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
926550003304	active site
926550003305	CoA binding site [chemical binding]; other site
926550003306	acyl-activating enzyme (AAE) consensus motif; other site
926550003307	AMP binding site [chemical binding]; other site
926550003308	acetate binding site [chemical binding]; other site
926550003309	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550003310	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550003311	ATP binding site [chemical binding]; other site
926550003312	Mg2+ binding site [ion binding]; other site
926550003313	G-X-G motif; other site
926550003314	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550003315	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550003316	active site
926550003317	phosphorylation site [posttranslational modification]
926550003318	intermolecular recognition site; other site
926550003319	dimerization interface [polypeptide binding]; other site
926550003320	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550003321	DNA binding residues [nucleotide binding]
926550003322	dimerization interface [polypeptide binding]; other site
926550003323	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550003324	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
926550003325	inhibitor-cofactor binding pocket; inhibition site
926550003326	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550003327	catalytic residue [active]
926550003328	Neutral/alkaline non-lysosomal ceramidase; Region: Ceramidase_alk; cl04712
926550003329	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550003330	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003331	dimer interface [polypeptide binding]; other site
926550003332	conserved gate region; other site
926550003333	putative PBP binding loops; other site
926550003334	ABC-ATPase subunit interface; other site
926550003335	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003336	dimer interface [polypeptide binding]; other site
926550003337	conserved gate region; other site
926550003338	putative PBP binding loops; other site
926550003339	ABC-ATPase subunit interface; other site
926550003340	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550003341	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550003342	aspartate kinase; Provisional; Region: PRK06291
926550003343	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
926550003344	putative catalytic residues [active]
926550003345	nucleotide binding site [chemical binding]; other site
926550003346	aspartate binding site [chemical binding]; other site
926550003347	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
926550003348	dimer interface [polypeptide binding]; other site
926550003349	putative threonine allosteric regulatory site; other site
926550003350	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
926550003351	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003352	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550003353	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003354	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550003355	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003356	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550003357	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003358	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926550003359	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
926550003360	thiamine-monophosphate kinase; Region: thiL; TIGR01379
926550003361	dimerization interface [polypeptide binding]; other site
926550003362	ATP binding site [chemical binding]; other site
926550003363	Domain of unknown function (DUF2088); Region: DUF2088; cl15406
926550003364	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
926550003365	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
926550003366	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
926550003367	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
926550003368	active site
926550003369	PHP Thumb interface [polypeptide binding]; other site
926550003370	metal binding site [ion binding]; metal-binding site
926550003371	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
926550003372	generic binding surface II; other site
926550003373	generic binding surface I; other site
926550003374	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
926550003375	RNA/DNA hybrid binding site [nucleotide binding]; other site
926550003376	active site
926550003377	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
926550003378	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
926550003379	Mg++ binding site [ion binding]; other site
926550003380	putative catalytic motif [active]
926550003381	substrate binding site [chemical binding]; other site
926550003382	O-Antigen ligase; Region: Wzy_C; cl04850
926550003383	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
926550003384	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
926550003385	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550003386	TPR motif; other site
926550003387	binding surface
926550003388	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550003389	binding surface
926550003390	TPR motif; other site
926550003391	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550003392	binding surface
926550003393	TPR motif; other site
926550003394	Protein of unknown function (DUF2029); Region: DUF2029; pfam09594
926550003395	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550003396	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550003397	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550003398	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_4; cd03795
926550003399	putative ADP-binding pocket [chemical binding]; other site
926550003400	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550003401	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550003402	Probable Catalytic site; other site
926550003403	metal-binding site
926550003404	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
926550003405	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550003406	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4641
926550003407	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
926550003408	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550003409	CDP-tyvelose 2-epimerase, extended (e) SDRs; Region: CDP_TE_SDR_e; cd05258
926550003410	NAD binding site [chemical binding]; other site
926550003411	homotetramer interface [polypeptide binding]; other site
926550003412	homodimer interface [polypeptide binding]; other site
926550003413	active site
926550003414	substrate binding site [chemical binding]; other site
926550003415	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550003416	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
926550003417	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926550003418	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
926550003419	active site
926550003420	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550003421	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550003422	NAD(P) binding site [chemical binding]; other site
926550003423	active site
926550003424	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550003425	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550003426	NAD(P) binding site [chemical binding]; other site
926550003427	active site
926550003428	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
926550003429	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550003430	inhibitor-cofactor binding pocket; inhibition site
926550003431	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550003432	catalytic residue [active]
926550003433	CDP-glucose 4,6-dehydratase; Region: CDP_4_6_dhtase; TIGR02622
926550003434	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550003435	NAD(P) binding site [chemical binding]; other site
926550003436	active site
926550003437	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
926550003438	G1P_cytidylyltransferase catalyzes the production of CDP-D-Glucose; Region: G1P_cytidylyltransferase; cd02524
926550003439	substrate binding site; other site
926550003440	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
926550003441	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
926550003442	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550003443	binding surface
926550003444	TPR repeat; Region: TPR_11; pfam13414
926550003445	TPR motif; other site
926550003446	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550003447	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550003448	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926550003449	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550003450	S-adenosylmethionine binding site [chemical binding]; other site
926550003451	protoheme IX farnesyltransferase; Provisional; Region: PRK04375
926550003452	UbiA prenyltransferase family; Region: UbiA; pfam01040
926550003453	SURF1 superfamily. Surf1/Shy1 has been implicated in the posttranslational steps of the biogenesis of the mitochondrially-encoded Cox1 subunit of cytochrome c oxidase (complex IV). Cytochrome c oxidase (complex IV), the terminal electron-transferring...; Region: SURF1; cd06662
926550003454	YtkA-like; Region: YtkA; pfam13115
926550003455	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
926550003456	Heme-copper oxidase subunit III.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which couple the reduction of molecular oxygen to water to, proton pumping across the membrane. The...; Region: Heme_Cu_Oxidase_III_like; cd00386
926550003457	Subunit I/III interface [polypeptide binding]; other site
926550003458	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
926550003459	cytochrome c oxidase, subunit I; Region: CtaD_CoxA; TIGR02891
926550003460	Virulence factor BrkB; Region: Virul_fac_BrkB; cl07918
926550003461	cytochrome c oxidase, subunit II; Region: CoxB; TIGR02866
926550003462	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926550003463	ferric uptake regulator; Provisional; Region: fur; PRK09462
926550003464	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
926550003465	metal binding site 2 [ion binding]; metal-binding site
926550003466	putative DNA binding helix; other site
926550003467	metal binding site 1 [ion binding]; metal-binding site
926550003468	dimer interface [polypeptide binding]; other site
926550003469	structural Zn2+ binding site [ion binding]; other site
926550003470	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550003471	heavy metal translocating P-type ATPase; Region: ATPase-IB_hvy; TIGR01525
926550003472	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926550003473	VPS10 domain; Region: VPS10; smart00602
926550003474	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
926550003475	active site
926550003476	catalytic residues [active]
926550003477	metal binding site [ion binding]; metal-binding site
926550003478	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926550003479	non-specific DNA binding site [nucleotide binding]; other site
926550003480	salt bridge; other site
926550003481	sequence-specific DNA binding site [nucleotide binding]; other site
926550003482	Bacterial SH3 domain; Region: SH3_3; cl17532
926550003483	VWA domain containing CoxE-like protein; Region: VWA_CoxE; pfam05762
926550003484	MoxR-like ATPases [General function prediction only]; Region: COG0714
926550003485	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003486	Walker A motif; other site
926550003487	ATP binding site [chemical binding]; other site
926550003488	Walker B motif; other site
926550003489	arginine finger; other site
926550003490	acetyl-CoA acetyltransferase; Provisional; Region: PRK07661
926550003491	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926550003492	dimer interface [polypeptide binding]; other site
926550003493	active site
926550003494	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
926550003495	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK09260
926550003496	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926550003497	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
926550003498	Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism]; Region: CaiD; COG1024
926550003499	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926550003500	substrate binding site [chemical binding]; other site
926550003501	oxyanion hole (OAH) forming residues; other site
926550003502	trimer interface [polypeptide binding]; other site
926550003503	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cl03181
926550003504	active site
926550003505	Alkaline and neutral invertase; Region: Glyco_hydro_100; cl17340
926550003506	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; cl00674
926550003507	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cd00190
926550003508	cleavage site
926550003509	active site
926550003510	substrate binding sites [chemical binding]; other site
926550003511	Clostripain family; Region: Peptidase_C11; pfam03415
926550003512	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550003513	active site residue [active]
926550003514	YtkA-like; Region: YtkA; pfam13115
926550003515	di-heme enzyme, MXAN_0977 family; Region: MXAN_0977_Heme2; TIGR04039
926550003516	META domain; Region: META; pfam03724
926550003517	META domain; Region: META; pfam03724
926550003518	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
926550003519	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003520	dimer interface [polypeptide binding]; other site
926550003521	conserved gate region; other site
926550003522	putative PBP binding loops; other site
926550003523	ABC-ATPase subunit interface; other site
926550003524	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
926550003525	Glucose inhibited division protein A; Region: GIDA; pfam01134
926550003526	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550003527	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550003528	putative substrate translocation pore; other site
926550003529	S-formylglutathione hydrolase; Region: PLN02442
926550003530	Putative esterase; Region: Esterase; pfam00756
926550003531	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
926550003532	Domain of unknown function (DUF814); Region: DUF814; pfam05670
926550003533	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
926550003534	dimer interface [polypeptide binding]; other site
926550003535	NADPH bind site [chemical binding]; other site
926550003536	FMN binding site [chemical binding]; other site
926550003537	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003538	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550003539	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003540	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
926550003541	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550003542	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926550003543	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926550003544	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550003545	inhibitor-cofactor binding pocket; inhibition site
926550003546	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550003547	catalytic residue [active]
926550003548	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
926550003549	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
926550003550	Ligand binding site; other site
926550003551	Putative Catalytic site; other site
926550003552	DXD motif; other site
926550003553	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550003554	S-adenosylmethionine binding site [chemical binding]; other site
926550003555	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
926550003556	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926550003557	active site 2 [active]
926550003558	active site 1 [active]
926550003559	probable carbamoyltransferase YgeW; Region: ygeW; TIGR03316
926550003560	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
926550003561	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
926550003562	tryptophanase/L-cysteine desulfhydrase, PLP-dependent; Provisional; Region: tnaA; PRK13238
926550003563	Tryptophanase family (Tnase). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to tryptophanase (Tnase) and tyrosine phenol-lyase (TPL). Tnase and TPL are...; Region: Tnase_like; cd00617
926550003564	substrate binding site [chemical binding]; other site
926550003565	tetramer interface [polypeptide binding]; other site
926550003566	catalytic residue [active]
926550003567	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550003568	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003569	Walker A/P-loop; other site
926550003570	ATP binding site [chemical binding]; other site
926550003571	Q-loop/lid; other site
926550003572	ABC transporter signature motif; other site
926550003573	Walker B; other site
926550003574	D-loop; other site
926550003575	H-loop/switch region; other site
926550003576	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550003577	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550003578	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003579	Walker A/P-loop; other site
926550003580	ATP binding site [chemical binding]; other site
926550003581	Q-loop/lid; other site
926550003582	ABC transporter signature motif; other site
926550003583	Walker B; other site
926550003584	D-loop; other site
926550003585	H-loop/switch region; other site
926550003586	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550003587	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550003588	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003589	dimer interface [polypeptide binding]; other site
926550003590	conserved gate region; other site
926550003591	putative PBP binding loops; other site
926550003592	ABC-ATPase subunit interface; other site
926550003593	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550003594	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003595	putative PBP binding loops; other site
926550003596	dimer interface [polypeptide binding]; other site
926550003597	ABC-ATPase subunit interface; other site
926550003598	potential frameshift: common BLAST hit: gi|305663368|ref|YP_003859656.1| ABC transporter substrate-binding protein
926550003599	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003600	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003601	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
926550003602	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003603	Walker A/P-loop; other site
926550003604	ATP binding site [chemical binding]; other site
926550003605	Q-loop/lid; other site
926550003606	ABC transporter signature motif; other site
926550003607	Walker B; other site
926550003608	D-loop; other site
926550003609	H-loop/switch region; other site
926550003610	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550003611	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550003612	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003613	Walker A/P-loop; other site
926550003614	ATP binding site [chemical binding]; other site
926550003615	Q-loop/lid; other site
926550003616	ABC transporter signature motif; other site
926550003617	Walker B; other site
926550003618	D-loop; other site
926550003619	H-loop/switch region; other site
926550003620	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550003621	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550003622	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003623	dimer interface [polypeptide binding]; other site
926550003624	conserved gate region; other site
926550003625	putative PBP binding loops; other site
926550003626	ABC-ATPase subunit interface; other site
926550003627	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550003628	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003629	dimer interface [polypeptide binding]; other site
926550003630	conserved gate region; other site
926550003631	putative PBP binding loops; other site
926550003632	ABC-ATPase subunit interface; other site
926550003633	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003634	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550003635	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003636	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550003637	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
926550003638	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003639	Walker A/P-loop; other site
926550003640	ATP binding site [chemical binding]; other site
926550003641	Q-loop/lid; other site
926550003642	ABC transporter signature motif; other site
926550003643	Walker B; other site
926550003644	D-loop; other site
926550003645	H-loop/switch region; other site
926550003646	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550003647	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550003648	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550003649	Walker A/P-loop; other site
926550003650	ATP binding site [chemical binding]; other site
926550003651	Q-loop/lid; other site
926550003652	ABC transporter signature motif; other site
926550003653	Walker B; other site
926550003654	D-loop; other site
926550003655	H-loop/switch region; other site
926550003656	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550003657	argininosuccinate lyase; Region: PLN02646
926550003658	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
926550003659	active sites [active]
926550003660	tetramer interface [polypeptide binding]; other site
926550003661	CAAX protease self-immunity; Region: Abi; pfam02517
926550003662	Domain of unknown function (DUF1992); Region: DUF1992; pfam09350
926550003663	hypothetical protein; Validated; Region: PRK07682
926550003664	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550003665	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550003666	homodimer interface [polypeptide binding]; other site
926550003667	catalytic residue [active]
926550003668	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926550003669	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
926550003670	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
926550003671	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
926550003672	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
926550003673	purine monophosphate binding site [chemical binding]; other site
926550003674	dimer interface [polypeptide binding]; other site
926550003675	putative catalytic residues [active]
926550003676	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
926550003677	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
926550003678	Uncharacterized conserved protein [Function unknown]; Region: COG3342
926550003679	Family of unknown function (DUF1028); Region: DUF1028; pfam06267
926550003680	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550003681	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003682	putative PBP binding loops; other site
926550003683	dimer interface [polypeptide binding]; other site
926550003684	ABC-ATPase subunit interface; other site
926550003685	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550003686	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003687	dimer interface [polypeptide binding]; other site
926550003688	conserved gate region; other site
926550003689	putative PBP binding loops; other site
926550003690	ABC-ATPase subunit interface; other site
926550003691	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550003692	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550003693	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550003694	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550003695	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
926550003696	Walker A/P-loop; other site
926550003697	ATP binding site [chemical binding]; other site
926550003698	Q-loop/lid; other site
926550003699	ABC transporter signature motif; other site
926550003700	Walker B; other site
926550003701	D-loop; other site
926550003702	H-loop/switch region; other site
926550003703	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; pfam02660
926550003704	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926550003705	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550003706	Walker A/P-loop; other site
926550003707	ATP binding site [chemical binding]; other site
926550003708	Q-loop/lid; other site
926550003709	ABC transporter signature motif; other site
926550003710	Walker B; other site
926550003711	D-loop; other site
926550003712	H-loop/switch region; other site
926550003713	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550003714	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550003715	Walker A/P-loop; other site
926550003716	ATP binding site [chemical binding]; other site
926550003717	Q-loop/lid; other site
926550003718	ABC transporter signature motif; other site
926550003719	Walker B; other site
926550003720	D-loop; other site
926550003721	H-loop/switch region; other site
926550003722	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550003723	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550003724	TM-ABC transporter signature motif; other site
926550003725	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550003726	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550003727	TM-ABC transporter signature motif; other site
926550003728	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550003729	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
926550003730	dimerization interface [polypeptide binding]; other site
926550003731	ligand binding site [chemical binding]; other site
926550003732	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
926550003733	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
926550003734	CoA-binding site [chemical binding]; other site
926550003735	ATP-binding [chemical binding]; other site
926550003736	chaperone protein DnaJ; Region: DnaJ_bact; TIGR02349
926550003737	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
926550003738	HSP70 interaction site [polypeptide binding]; other site
926550003739	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
926550003740	substrate binding site [polypeptide binding]; other site
926550003741	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
926550003742	Zn binding sites [ion binding]; other site
926550003743	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
926550003744	dimer interface [polypeptide binding]; other site
926550003745	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
926550003746	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550003747	S-adenosylmethionine binding site [chemical binding]; other site
926550003748	RNA methyltransferase, RsmE family; Region: TIGR00046
926550003749	RNA methyltransferase; Region: Methyltrans_RNA; pfam04452
926550003750	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
926550003751	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
926550003752	motif 1; other site
926550003753	active site
926550003754	motif 2; other site
926550003755	motif 3; other site
926550003756	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
926550003757	DHHA1 domain; Region: DHHA1; pfam02272
926550003758	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
926550003759	YceG-like family; Region: YceG; pfam02618
926550003760	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
926550003761	dimerization interface [polypeptide binding]; other site
926550003762	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550003763	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
926550003764	ligand binding site [chemical binding]; other site
926550003765	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550003766	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550003767	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
926550003768	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
926550003769	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
926550003770	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
926550003771	Fe-S metabolism associated domain; Region: SufE; cl00951
926550003772	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
926550003773	Beta-lactamase; Region: Beta-lactamase; pfam00144
926550003774	Protein of unknown function (DUF541); Region: SIMPL; pfam04402
926550003775	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
926550003776	FOG: CBS domain [General function prediction only]; Region: COG0517
926550003777	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
926550003778	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550003779	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
926550003780	active site
926550003781	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
926550003782	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
926550003783	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
926550003784	active site
926550003785	homodimer interface [polypeptide binding]; other site
926550003786	catalytic site [active]
926550003787	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cd00190
926550003788	cleavage site
926550003789	active site
926550003790	substrate binding sites [chemical binding]; other site
926550003791	pterin-4-alpha-carbinolamine dehydratase; Validated; Region: phhB; PRK00823
926550003792	aromatic arch; other site
926550003793	DCoH dimer interaction site [polypeptide binding]; other site
926550003794	DCoH /HNF-1 dimer interaction site [polypeptide binding]; other site
926550003795	DCoH tetramer interaction site [polypeptide binding]; other site
926550003796	substrate binding site [chemical binding]; other site
926550003797	N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuB; COG0146
926550003798	Hydantoinase B/oxoprolinase; Region: Hydantoinase_B; pfam02538
926550003799	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
926550003800	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
926550003801	homodimer interface [polypeptide binding]; other site
926550003802	substrate-cofactor binding pocket; other site
926550003803	catalytic residue [active]
926550003804	N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building...; Region: NAAAR; cd03317
926550003805	o-succinylbenzoate synthase; Region: menC_lowGC/arch; TIGR01928
926550003806	active site
926550003807	octamer interface [polypeptide binding]; other site
926550003808	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
926550003809	nudix motif; other site
926550003810	DsrE/DsrF/DrsH-like family; Region: DrsE_2; cl17453
926550003811	Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism]; Region: DsrC; COG2920
926550003812	DsrC like protein; Region: DsrC; cl01101
926550003813	Uncharacterized conserved protein [Function unknown]; Region: COG2427
926550003814	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
926550003815	Helix-turn-helix domain; Region: HTH_17; pfam12728
926550003816	Sensory domain found in PocR; Region: PocR; pfam10114
926550003817	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
926550003818	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
926550003819	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
926550003820	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
926550003821	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
926550003822	deazaflavin-dependent oxidoreductase, nitroreductase family; Region: hi_GC_TIGR00026
926550003823	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
926550003824	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
926550003825	DHH family; Region: DHH; pfam01368
926550003826	FOG: CBS domain [General function prediction only]; Region: COG0517
926550003827	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with an upstream DHH domain which performs a phosphoesterase function and a downstream polyA polymerase domain. CBS is a small domain originally...; Region: CBS_pair_DHH_polyA_Pol_assoc; cd04595
926550003828	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
926550003829	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
926550003830	active site
926550003831	NTP binding site [chemical binding]; other site
926550003832	metal binding triad [ion binding]; metal-binding site
926550003833	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
926550003834	ferredoxin-NADP+ reductase; Region: PLN02852
926550003835	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550003836	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550003837	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926550003838	Metal-binding active site; metal-binding site
926550003839	Protein of unknown function (DUF2424); Region: DUF2424; pfam10340
926550003840	alpha/beta hydrolase fold; Region: Abhydrolase_3; pfam07859
926550003841	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
926550003842	putative rRNA binding site [nucleotide binding]; other site
926550003843	ATP-dependent Clp protease adaptor protein ClpS; Region: ClpS; pfam02617
926550003844	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
926550003845	Ligand binding site; other site
926550003846	Putative Catalytic site; other site
926550003847	DXD motif; other site
926550003848	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550003849	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
926550003850	Protein of unknown function (DUF556); Region: DUF556; cl00822
926550003851	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
926550003852	active site
926550003853	catalytic residues [active]
926550003854	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
926550003855	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
926550003856	Bacterial SH3 domain homologues; Region: SH3b; smart00287
926550003857	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
926550003858	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
926550003859	NodB motif; other site
926550003860	active site
926550003861	catalytic site [active]
926550003862	metal binding site [ion binding]; metal-binding site
926550003863	Uncharacterized protein related to deoxyribodipyrimidine photolyase [General function prediction only]; Region: COG3046
926550003864	Deoxyribodipyrimidine photo-lyase-related protein; Region: DPRP; pfam04244
926550003865	DNA repair protein RadA; Provisional; Region: PRK11823
926550003866	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
926550003867	Walker A motif/ATP binding site; other site
926550003868	ATP binding site [chemical binding]; other site
926550003869	Walker B motif; other site
926550003870	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
926550003871	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550003872	Predicted membrane protein (DUF2339); Region: DUF2339; pfam10101
926550003873	Uncharacterized conserved protein [Function unknown]; Region: COG1262
926550003874	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
926550003875	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
926550003876	Bifunctional nuclease; Region: DNase-RNase; pfam02577
926550003877	replicative DNA helicase; Region: DnaB; TIGR00665
926550003878	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
926550003879	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
926550003880	Walker A motif; other site
926550003881	ATP binding site [chemical binding]; other site
926550003882	Walker B motif; other site
926550003883	DNA binding loops [nucleotide binding]
926550003884	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
926550003885	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003886	Walker A motif; other site
926550003887	ATP binding site [chemical binding]; other site
926550003888	Walker B motif; other site
926550003889	arginine finger; other site
926550003890	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003891	Walker A motif; other site
926550003892	ATP binding site [chemical binding]; other site
926550003893	Walker B motif; other site
926550003894	arginine finger; other site
926550003895	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
926550003896	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550003897	S-adenosylmethionine binding site [chemical binding]; other site
926550003898	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
926550003899	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
926550003900	CoA binding domain; Region: CoA_binding; pfam02629
926550003901	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550003902	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550003903	active site
926550003904	phosphorylation site [posttranslational modification]
926550003905	intermolecular recognition site; other site
926550003906	dimerization interface [polypeptide binding]; other site
926550003907	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550003908	DNA binding site [nucleotide binding]
926550003909	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
926550003910	C-terminal peptidase (prc); Region: prc; TIGR00225
926550003911	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
926550003912	protein binding site [polypeptide binding]; other site
926550003913	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
926550003914	Catalytic dyad [active]
926550003915	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
926550003916	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
926550003917	active site
926550003918	(T/H)XGH motif; other site
926550003919	GTPase CgtA; Reviewed; Region: obgE; PRK12297
926550003920	GTP1/OBG; Region: GTP1_OBG; pfam01018
926550003921	Obg GTPase; Region: Obg; cd01898
926550003922	G1 box; other site
926550003923	GTP/Mg2+ binding site [chemical binding]; other site
926550003924	Switch I region; other site
926550003925	G2 box; other site
926550003926	G3 box; other site
926550003927	Switch II region; other site
926550003928	G4 box; other site
926550003929	G5 box; other site
926550003930	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
926550003931	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
926550003932	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
926550003933	active site
926550003934	catalytic site [active]
926550003935	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
926550003936	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG4584
926550003937	Integrase core domain; Region: rve; pfam00665
926550003938	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550003939	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926550003940	Walker A motif; other site
926550003941	ATP binding site [chemical binding]; other site
926550003942	Walker B motif; other site
926550003943	arginine finger; other site
926550003944	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
926550003945	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
926550003946	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
926550003947	CRISPR/Cas system-associated protein Csx15; Region: Csx15_I-U; cd09766
926550003948	Bacterial SH3 domain; Region: SH3_3; cl17532
926550003949	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
926550003950	CRISPR-associated (Cas) DxTHG family; Region: Cas_DxTHG; pfam09455
926550003951	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cd09732
926550003952	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl17439
926550003953	CRISPR/Cas system-associated RAMP superfamily protein Csm5; Region: Csm5_III-A; cl17437
926550003954	CRISPR/Cas system-associated RAMP superfamily protein Csm4; Region: Csm4_III-A; cl17438
926550003955	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
926550003956	CRISPR/Cas system-associated protein Csm2; Region: Csm2_III-A; cd09647
926550003957	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cd09680
926550003958	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cd09680
926550003959	CRISPR/Cas system-associated protein Csx1; Region: Csx1_III-U; cl09839
926550003960	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550003961	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550003962	DNA binding residues [nucleotide binding]
926550003963	CRISPR/Cas system-associated protein Csx3; Region: Csx3_III-U; cl09837
926550003964	phosphoenolpyruvate synthase; Validated; Region: PRK06464
926550003965	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
926550003966	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926550003967	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926550003968	Citrate synthase (CS), citryl-CoA lyase (CCL), the C-terminal portion of the single-subunit type ATP-citrate lyase (ACL) and the C-terminal portion of the large subunit of the two-subunit type ACL. CS catalyzes the condensation of acetyl coenzyme A; Region: CS_ACL-C_CCL; cl00416
926550003969	Citrate synthase; Region: Citrate_synt; pfam00285
926550003970	oxalacetate binding site [chemical binding]; other site
926550003971	citrylCoA binding site [chemical binding]; other site
926550003972	coenzyme A binding site [chemical binding]; other site
926550003973	catalytic triad [active]
926550003974	Beta-galactosidase [Carbohydrate transport and metabolism]; Region: LacA; COG1874
926550003975	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
926550003976	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
926550003977	Beta-galactosidase C-terminal domain; Region: Glyco_hydro_42C; pfam08533
926550003978	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550003979	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003980	dimer interface [polypeptide binding]; other site
926550003981	conserved gate region; other site
926550003982	putative PBP binding loops; other site
926550003983	ABC-ATPase subunit interface; other site
926550003984	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550003985	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550003986	dimer interface [polypeptide binding]; other site
926550003987	conserved gate region; other site
926550003988	putative PBP binding loops; other site
926550003989	ABC-ATPase subunit interface; other site
926550003990	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550003991	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550003992	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550003993	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550003994	DNA binding site [nucleotide binding]
926550003995	domain linker motif; other site
926550003996	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550003997	dimerization interface [polypeptide binding]; other site
926550003998	ligand binding site [chemical binding]; other site
926550003999	Thermus thermophilus CsoR, a Cu(I)-sensing transcriptional regulator, and related domains; this domain family was previously known as part of DUF156; Region: TthCsoR-like_DUF156; cd10151
926550004000	putative homodimer interface [polypeptide binding]; other site
926550004001	putative homotetramer interface [polypeptide binding]; other site
926550004002	allosteric switch controlling residues; other site
926550004003	putative metal binding site [ion binding]; other site
926550004004	putative homodimer-homodimer interface [polypeptide binding]; other site
926550004005	Copper chaperone [Inorganic ion transport and metabolism]; Region: CopZ; COG2608
926550004006	metal-binding site [ion binding]
926550004007	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926550004008	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926550004009	metal-binding site [ion binding]
926550004010	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926550004011	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926550004012	metal-binding site [ion binding]
926550004013	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550004014	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926550004015	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550004016	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; cl01046
926550004017	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550004018	Predicted transcriptional regulators [Transcription]; Region: COG1733
926550004019	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550004020	dimerization interface [polypeptide binding]; other site
926550004021	putative DNA binding site [nucleotide binding]; other site
926550004022	putative Zn2+ binding site [ion binding]; other site
926550004023	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926550004024	Domain of unknown function (DUF2007); Region: DUF2007; pfam09413
926550004025	CcmE; Region: CcmE; cl00994
926550004026	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550004027	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
926550004028	Walker A/P-loop; other site
926550004029	ATP binding site [chemical binding]; other site
926550004030	Q-loop/lid; other site
926550004031	ABC transporter signature motif; other site
926550004032	Walker B; other site
926550004033	D-loop; other site
926550004034	H-loop/switch region; other site
926550004035	CcmB protein; Region: CcmB; cl17444
926550004036	Cytochrome C assembly protein; Region: Cytochrom_C_asm; cl00504
926550004037	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
926550004038	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
926550004039	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
926550004040	Glutaredoxin-like domain (DUF836); Region: DUF836; cl17650
926550004041	Predicted membrane protein (DUF2085); Region: DUF2085; pfam09858
926550004042	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
926550004043	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
926550004044	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926550004045	minor groove reading motif; other site
926550004046	helix-hairpin-helix signature motif; other site
926550004047	substrate binding pocket [chemical binding]; other site
926550004048	active site
926550004049	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
926550004050	alanine racemase; Reviewed; Region: alr; PRK00053
926550004051	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
926550004052	active site
926550004053	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926550004054	dimer interface [polypeptide binding]; other site
926550004055	substrate binding site [chemical binding]; other site
926550004056	catalytic residues [active]
926550004057	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
926550004058	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
926550004059	active site
926550004060	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
926550004061	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
926550004062	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550004063	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550004064	DNA binding residues [nucleotide binding]
926550004065	CTP synthetase; Validated; Region: pyrG; PRK05380
926550004066	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
926550004067	Catalytic site [active]
926550004068	active site
926550004069	UTP binding site [chemical binding]; other site
926550004070	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
926550004071	active site
926550004072	putative oxyanion hole; other site
926550004073	catalytic triad [active]
926550004074	hypothetical protein; Validated; Region: PRK00110
926550004075	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
926550004076	active site
926550004077	putative DNA-binding cleft [nucleotide binding]; other site
926550004078	dimer interface [polypeptide binding]; other site
926550004079	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550004080	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004081	active site
926550004082	phosphorylation site [posttranslational modification]
926550004083	intermolecular recognition site; other site
926550004084	dimerization interface [polypeptide binding]; other site
926550004085	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550004086	DNA binding site [nucleotide binding]
926550004087	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
926550004088	RuvA N terminal domain; Region: RuvA_N; pfam01330
926550004089	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
926550004090	elongation factor P; Validated; Region: PRK00529
926550004091	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
926550004092	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
926550004093	RNA binding site [nucleotide binding]; other site
926550004094	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
926550004095	RNA binding site [nucleotide binding]; other site
926550004096	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
926550004097	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550004098	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
926550004099	Glycoprotease family; Region: Peptidase_M22; pfam00814
926550004100	Aldehyde:ferredoxin oxidoreductase [Energy production and conversion]; Region: COG2414
926550004101	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
926550004102	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
926550004103	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
926550004104	putative deacylase active site [active]
926550004105	glutamate carboxypeptidase; Reviewed; Region: PRK06133
926550004106	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
926550004107	metal binding site [ion binding]; metal-binding site
926550004108	dimer interface [polypeptide binding]; other site
926550004109	DNA adenine methylase (dam); Region: dam; TIGR00571
926550004110	lipoyl synthase; Provisional; Region: PRK05481
926550004111	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
926550004112	Cytochrome P450; Region: p450; cl12078
926550004113	Protein of unknown function, DUF417; Region: DUF417; cl01162
926550004114	heat shock protein 90; Provisional; Region: PRK05218
926550004115	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004116	ATP binding site [chemical binding]; other site
926550004117	Mg2+ binding site [ion binding]; other site
926550004118	G-X-G motif; other site
926550004119	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; smart01007
926550004120	active site
926550004121	intersubunit interface [polypeptide binding]; other site
926550004122	Zn2+ binding site [ion binding]; other site
926550004123	Domain of unknown function (DU1801); Region: DUF1801; pfam08818
926550004124	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
926550004125	hydrophobic ligand binding site; other site
926550004126	2-phospho-L-lactate guanylyltransferase; Region: F420_cofC; TIGR03552
926550004127	LPPG:FO 2-phospho-L-lactate transferase; important in F420 biosynthesis; Region: CofD_like; cd07186
926550004128	Uncharacterized protein family UPF0052; Region: UPF0052; pfam01933
926550004129	dimer interface [polypeptide binding]; other site
926550004130	substrate binding site [chemical binding]; other site
926550004131	phosphate binding site [ion binding]; other site
926550004132	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
926550004133	putative FMN binding site [chemical binding]; other site
926550004134	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550004135	FtsX-like permease family; Region: FtsX; pfam02687
926550004136	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
926550004137	FtsX-like permease family; Region: FtsX; pfam02687
926550004138	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550004139	Walker A/P-loop; other site
926550004140	ATP binding site [chemical binding]; other site
926550004141	ABC transporter; Region: ABC_tran; pfam00005
926550004142	Q-loop/lid; other site
926550004143	ABC transporter signature motif; other site
926550004144	Walker B; other site
926550004145	D-loop; other site
926550004146	H-loop/switch region; other site
926550004147	radical SAM protein, BA_1875 family; Region: sam_11; TIGR04053
926550004148	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550004149	FeS/SAM binding site; other site
926550004150	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
926550004151	Uncharacterized conserved protein (DUF2249); Region: DUF2249; cl17719
926550004152	mercuric reductase; Validated; Region: PRK06370
926550004153	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
926550004154	Alpha-L-fucosidase; Region: Alpha_L_fucos; pfam01120
926550004155	alpha-galactosidase; Provisional; Region: PRK15076
926550004156	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
926550004157	NAD binding site [chemical binding]; other site
926550004158	sugar binding site [chemical binding]; other site
926550004159	divalent metal binding site [ion binding]; other site
926550004160	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550004161	dimer interface [polypeptide binding]; other site
926550004162	alpha-galactosidase; Provisional; Region: PRK15076
926550004163	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
926550004164	NAD binding site [chemical binding]; other site
926550004165	sugar binding site [chemical binding]; other site
926550004166	divalent metal binding site [ion binding]; other site
926550004167	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550004168	dimer interface [polypeptide binding]; other site
926550004169	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550004170	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550004171	Walker A/P-loop; other site
926550004172	ATP binding site [chemical binding]; other site
926550004173	Q-loop/lid; other site
926550004174	ABC transporter signature motif; other site
926550004175	Walker B; other site
926550004176	D-loop; other site
926550004177	H-loop/switch region; other site
926550004178	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550004179	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550004180	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004181	dimer interface [polypeptide binding]; other site
926550004182	conserved gate region; other site
926550004183	putative PBP binding loops; other site
926550004184	ABC-ATPase subunit interface; other site
926550004185	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550004186	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004187	dimer interface [polypeptide binding]; other site
926550004188	conserved gate region; other site
926550004189	putative PBP binding loops; other site
926550004190	ABC-ATPase subunit interface; other site
926550004191	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550004192	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550004193	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550004194	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550004195	Walker A/P-loop; other site
926550004196	ATP binding site [chemical binding]; other site
926550004197	Q-loop/lid; other site
926550004198	ABC transporter signature motif; other site
926550004199	Walker B; other site
926550004200	D-loop; other site
926550004201	H-loop/switch region; other site
926550004202	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550004203	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550004204	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004205	active site
926550004206	phosphorylation site [posttranslational modification]
926550004207	intermolecular recognition site; other site
926550004208	dimerization interface [polypeptide binding]; other site
926550004209	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550004210	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550004211	ligand binding site [chemical binding]; other site
926550004212	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550004213	GAF domain; Region: GAF; cl17456
926550004214	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550004215	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550004216	dimer interface [polypeptide binding]; other site
926550004217	phosphorylation site [posttranslational modification]
926550004218	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004219	ATP binding site [chemical binding]; other site
926550004220	Mg2+ binding site [ion binding]; other site
926550004221	G-X-G motif; other site
926550004222	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
926550004223	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550004224	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550004225	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926550004226	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926550004227	inhibitor site; inhibition site
926550004228	active site
926550004229	dimer interface [polypeptide binding]; other site
926550004230	catalytic residue [active]
926550004231	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
926550004232	active site
926550004233	DNA binding site [nucleotide binding]
926550004234	4-aminobutyrate aminotransferase and related aminotransferases [Amino acid transport and metabolism]; Region: GabT; COG0160
926550004235	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550004236	inhibitor-cofactor binding pocket; inhibition site
926550004237	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550004238	catalytic residue [active]
926550004239	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
926550004240	transmembrane helices; other site
926550004241	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
926550004242	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926550004243	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550004244	Winged helix-turn helix; Region: HTH_29; pfam13551
926550004245	Helix-turn-helix domain; Region: HTH_28; pfam13518
926550004246	Homeodomain-like domain; Region: HTH_32; pfam13565
926550004247	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550004248	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
926550004249	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
926550004250	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
926550004251	shikimate binding site; other site
926550004252	NAD(P) binding site [chemical binding]; other site
926550004253	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
926550004254	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550004255	Coenzyme A binding pocket [chemical binding]; other site
926550004256	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
926550004257	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
926550004258	active site
926550004259	hinge; other site
926550004260	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550004261	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004262	dimer interface [polypeptide binding]; other site
926550004263	conserved gate region; other site
926550004264	putative PBP binding loops; other site
926550004265	ABC-ATPase subunit interface; other site
926550004266	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550004267	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004268	dimer interface [polypeptide binding]; other site
926550004269	conserved gate region; other site
926550004270	putative PBP binding loops; other site
926550004271	ABC-ATPase subunit interface; other site
926550004272	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
926550004273	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550004274	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
926550004275	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
926550004276	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550004277	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); Region: PCMT; pfam01135
926550004278	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550004279	S-adenosylmethionine binding site [chemical binding]; other site
926550004280	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
926550004281	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
926550004282	NADP binding site [chemical binding]; other site
926550004283	active site
926550004284	putative substrate binding site [chemical binding]; other site
926550004285	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926550004286	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550004287	Probable Catalytic site; other site
926550004288	metal-binding site
926550004289	Domain of unknown function DUF87; Region: DUF87; pfam01935
926550004290	HerA helicase [Replication, recombination, and repair]; Region: COG0433
926550004291	Zonular occludens toxin (Zot); Region: Zot; cl17485
926550004292	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550004293	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
926550004294	Coenzyme A binding pocket [chemical binding]; other site
926550004295	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550004296	microbial_RNases. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential  for both non-specific RNA degradation and for numerous forms of RNA processing. The alignment contains fungal RNases (U2, T1, F1, Th,  Pb, N1, and Ms) and...; Region: microbial_RNases; cl00212
926550004297	active site
926550004298	Barstar_evA4336-like contains uncharacterized sequences similar to the uncharacterized, predicted RNAase inhibitor evA4336 found in Azoarcus sp. EvN1. This is a subfamily of the Barstar family of RNAase inhibitors. Barstar is an intracellular inhibitor...; Region: Barstar_evA4336-like; cd05141
926550004299	putative RNAase interaction site [polypeptide binding]; other site
926550004300	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
926550004301	active site
926550004302	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550004303	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550004304	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550004305	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550004306	putative active site [active]
926550004307	heme pocket [chemical binding]; other site
926550004308	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550004309	dimer interface [polypeptide binding]; other site
926550004310	phosphorylation site [posttranslational modification]
926550004311	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004312	ATP binding site [chemical binding]; other site
926550004313	Mg2+ binding site [ion binding]; other site
926550004314	G-X-G motif; other site
926550004315	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
926550004316	active site
926550004317	catalytic motif [active]
926550004318	Zn binding site [ion binding]; other site
926550004319	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
926550004320	Domain of unknown function DUF21; Region: DUF21; pfam01595
926550004321	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926550004322	Transporter associated domain; Region: CorC_HlyC; smart01091
926550004323	N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane]; Region: GlmU; COG1207
926550004324	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550004325	active site
926550004326	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
926550004327	active site
926550004328	substrate binding site [chemical binding]; other site
926550004329	CoA binding site [chemical binding]; other site
926550004330	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550004331	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926550004332	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
926550004333	metal ion-dependent adhesion site (MIDAS); other site
926550004334	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550004335	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550004336	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
926550004337	active site
926550004338	Glycoside hydrolase family 44; Region: Glyco_hydro_44; pfam12891
926550004339	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550004340	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004341	dimer interface [polypeptide binding]; other site
926550004342	conserved gate region; other site
926550004343	ABC-ATPase subunit interface; other site
926550004344	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550004345	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550004346	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004347	dimer interface [polypeptide binding]; other site
926550004348	conserved gate region; other site
926550004349	putative PBP binding loops; other site
926550004350	ABC-ATPase subunit interface; other site
926550004351	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550004352	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550004353	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550004354	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550004355	DNA binding site [nucleotide binding]
926550004356	domain linker motif; other site
926550004357	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550004358	dimerization interface [polypeptide binding]; other site
926550004359	ligand binding site [chemical binding]; other site
926550004360	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550004361	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
926550004362	FtsX-like permease family; Region: FtsX; pfam02687
926550004363	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
926550004364	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550004365	FtsX-like permease family; Region: FtsX; pfam02687
926550004366	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550004367	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550004368	Walker A/P-loop; other site
926550004369	ATP binding site [chemical binding]; other site
926550004370	Q-loop/lid; other site
926550004371	ABC transporter signature motif; other site
926550004372	Walker B; other site
926550004373	D-loop; other site
926550004374	H-loop/switch region; other site
926550004375	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550004376	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550004377	Walker A/P-loop; other site
926550004378	ATP binding site [chemical binding]; other site
926550004379	Q-loop/lid; other site
926550004380	ABC transporter signature motif; other site
926550004381	Walker B; other site
926550004382	D-loop; other site
926550004383	H-loop/switch region; other site
926550004384	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
926550004385	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550004386	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
926550004387	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004388	dimer interface [polypeptide binding]; other site
926550004389	conserved gate region; other site
926550004390	ABC-ATPase subunit interface; other site
926550004391	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004392	dimer interface [polypeptide binding]; other site
926550004393	conserved gate region; other site
926550004394	putative PBP binding loops; other site
926550004395	ABC-ATPase subunit interface; other site
926550004396	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926550004397	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550004398	Walker A/P-loop; other site
926550004399	ATP binding site [chemical binding]; other site
926550004400	Q-loop/lid; other site
926550004401	ABC transporter signature motif; other site
926550004402	Walker B; other site
926550004403	D-loop; other site
926550004404	H-loop/switch region; other site
926550004405	TOBE domain; Region: TOBE_2; pfam08402
926550004406	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
926550004407	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926550004408	Predicted dehydrogenase [General function prediction only]; Region: COG0579
926550004409	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926550004410	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
926550004411	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
926550004412	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550004413	Uncharacterized protein with conserved CXXC pairs [Function unknown]; Region: COG3862
926550004414	Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]; Region: Fmt; COG0223
926550004415	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
926550004416	putative active site [active]
926550004417	substrate binding site [chemical binding]; other site
926550004418	putative cosubstrate binding site; other site
926550004419	catalytic site [active]
926550004420	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
926550004421	trimer interface [polypeptide binding]; other site
926550004422	active site
926550004423	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
926550004424	homotrimer interface [polypeptide binding]; other site
926550004425	Walker A motif; other site
926550004426	GTP binding site [chemical binding]; other site
926550004427	Walker B motif; other site
926550004428	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550004429	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926550004430	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550004431	ATP binding site [chemical binding]; other site
926550004432	putative Mg++ binding site [ion binding]; other site
926550004433	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550004434	nucleotide binding region [chemical binding]; other site
926550004435	ATP-binding site [chemical binding]; other site
926550004436	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
926550004437	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
926550004438	active site
926550004439	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
926550004440	pyridoxamine-phosphate oxidase; Region: pdxH; TIGR00558
926550004441	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
926550004442	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region; Region: PNPOx_C; pfam10590
926550004443	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
926550004444	uncharacterized peroxidase-related enzyme; Region: peroxid_rel; TIGR01926
926550004445	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550004446	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
926550004447	ligand binding site [chemical binding]; other site
926550004448	dimerization interface [polypeptide binding]; other site
926550004449	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550004450	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550004451	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550004452	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004453	dimer interface [polypeptide binding]; other site
926550004454	conserved gate region; other site
926550004455	putative PBP binding loops; other site
926550004456	ABC-ATPase subunit interface; other site
926550004457	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550004458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004459	dimer interface [polypeptide binding]; other site
926550004460	conserved gate region; other site
926550004461	putative PBP binding loops; other site
926550004462	ABC-ATPase subunit interface; other site
926550004463	Predicted small integral membrane protein (DUF2160); Region: DUF2160; cl02294
926550004464	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550004465	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
926550004466	inhibitor binding site; inhibition site
926550004467	catalytic Zn binding site [ion binding]; other site
926550004468	structural Zn binding site [ion binding]; other site
926550004469	NADP binding site [chemical binding]; other site
926550004470	tetramer interface [polypeptide binding]; other site
926550004471	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550004472	short chain dehydrogenase; Provisional; Region: PRK06114
926550004473	NAD(P) binding site [chemical binding]; other site
926550004474	active site
926550004475	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550004476	L-threonine dehydrogenase; Region: threonine_DH_like; cd08234
926550004477	putative NAD(P) binding site [chemical binding]; other site
926550004478	catalytic Zn binding site [ion binding]; other site
926550004479	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550004480	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
926550004481	inhibitor binding site; inhibition site
926550004482	catalytic Zn binding site [ion binding]; other site
926550004483	structural Zn binding site [ion binding]; other site
926550004484	NADP binding site [chemical binding]; other site
926550004485	tetramer interface [polypeptide binding]; other site
926550004486	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
926550004487	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
926550004488	putative active site; other site
926550004489	catalytic residue [active]
926550004490	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550004491	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550004492	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004493	dimer interface [polypeptide binding]; other site
926550004494	conserved gate region; other site
926550004495	putative PBP binding loops; other site
926550004496	ABC-ATPase subunit interface; other site
926550004497	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550004498	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004499	putative PBP binding loops; other site
926550004500	dimer interface [polypeptide binding]; other site
926550004501	ABC-ATPase subunit interface; other site
926550004502	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550004503	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550004504	nucleotide binding site [chemical binding]; other site
926550004505	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550004506	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926550004507	substrate binding site [chemical binding]; other site
926550004508	ATP binding site [chemical binding]; other site
926550004509	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
926550004510	N- and C-terminal domain interface [polypeptide binding]; other site
926550004511	D-xylulose kinase; Region: XylB; TIGR01312
926550004512	active site
926550004513	MgATP binding site [chemical binding]; other site
926550004514	catalytic site [active]
926550004515	metal binding site [ion binding]; metal-binding site
926550004516	xylulose binding site [chemical binding]; other site
926550004517	homodimer interface [polypeptide binding]; other site
926550004518	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
926550004519	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
926550004520	putative substrate binding site [chemical binding]; other site
926550004521	putative ATP binding site [chemical binding]; other site
926550004522	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
926550004523	MgtE intracellular N domain; Region: MgtE_N; pfam03448
926550004524	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
926550004525	Divalent cation transporter; Region: MgtE; cl00786
926550004526	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550004527	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550004528	active site
926550004529	catalytic tetrad [active]
926550004530	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550004531	catalytic residues [active]
926550004532	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
926550004533	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
926550004534	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
926550004535	putative active site [active]
926550004536	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
926550004537	PA/protease or protease-like domain interface [polypeptide binding]; other site
926550004538	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550004539	catalytic residues [active]
926550004540	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550004541	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550004542	S-adenosylmethionine binding site [chemical binding]; other site
926550004543	ribonuclease PH; Reviewed; Region: rph; PRK00173
926550004544	Ribonuclease PH; Region: RNase_PH_bact; cd11362
926550004545	hexamer interface [polypeptide binding]; other site
926550004546	active site
926550004547	Predicted membrane protein [Function unknown]; Region: COG2311
926550004548	Protein of unknown function (DUF418); Region: DUF418; pfam04235
926550004549	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
926550004550	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550004551	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550004552	homodimer interface [polypeptide binding]; other site
926550004553	catalytic residue [active]
926550004554	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
926550004555	putative active site; other site
926550004556	putative metal binding residues [ion binding]; other site
926550004557	signature motif; other site
926550004558	putative triphosphate binding site [ion binding]; other site
926550004559	CHAD domain; Region: CHAD; pfam05235
926550004560	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550004561	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550004562	putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; Region: PhnT2; TIGR03265
926550004563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550004564	Walker A/P-loop; other site
926550004565	ATP binding site [chemical binding]; other site
926550004566	Q-loop/lid; other site
926550004567	ABC transporter signature motif; other site
926550004568	Walker B; other site
926550004569	D-loop; other site
926550004570	H-loop/switch region; other site
926550004571	TOBE domain; Region: TOBE_2; pfam08402
926550004572	putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262
926550004573	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004574	putative PBP binding loops; other site
926550004575	dimer interface [polypeptide binding]; other site
926550004576	ABC-ATPase subunit interface; other site
926550004577	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550004578	dimer interface [polypeptide binding]; other site
926550004579	conserved gate region; other site
926550004580	putative PBP binding loops; other site
926550004581	ABC-ATPase subunit interface; other site
926550004582	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550004583	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550004584	catalytic residue [active]
926550004585	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
926550004586	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550004587	motif II; other site
926550004588	Predicted permease [General function prediction only]; Region: COG2985
926550004589	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
926550004590	TrkA-C domain; Region: TrkA_C; pfam02080
926550004591	TrkA-C domain; Region: TrkA_C; pfam02080
926550004592	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
926550004593	Response regulator receiver domain; Region: Response_reg; pfam00072
926550004594	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004595	active site
926550004596	phosphorylation site [posttranslational modification]
926550004597	intermolecular recognition site; other site
926550004598	dimerization interface [polypeptide binding]; other site
926550004599	PAS domain; Region: PAS_8; pfam13188
926550004600	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550004601	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
926550004602	dimer interface [polypeptide binding]; other site
926550004603	phosphorylation site [posttranslational modification]
926550004604	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004605	ATP binding site [chemical binding]; other site
926550004606	Mg2+ binding site [ion binding]; other site
926550004607	G-X-G motif; other site
926550004608	Glutamine cyclotransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG3823
926550004609	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
926550004610	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
926550004611	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
926550004612	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
926550004613	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
926550004614	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
926550004615	dimerization interface [polypeptide binding]; other site
926550004616	putative ATP binding site [chemical binding]; other site
926550004617	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
926550004618	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
926550004619	active site
926550004620	substrate binding site [chemical binding]; other site
926550004621	cosubstrate binding site; other site
926550004622	catalytic site [active]
926550004623	Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]; Region: AdhC; COG1062
926550004624	Class III alcohol dehydrogenase; Region: Zn_ADH_class_III; cd08279
926550004625	NAD binding site [chemical binding]; other site
926550004626	catalytic Zn binding site [ion binding]; other site
926550004627	substrate binding site [chemical binding]; other site
926550004628	structural Zn binding site [ion binding]; other site
926550004629	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
926550004630	Coenzyme A binding pocket [chemical binding]; other site
926550004631	PAS domain; Region: PAS; smart00091
926550004632	PAS fold; Region: PAS_4; pfam08448
926550004633	putative active site [active]
926550004634	heme pocket [chemical binding]; other site
926550004635	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550004636	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550004637	putative active site [active]
926550004638	heme pocket [chemical binding]; other site
926550004639	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550004640	dimer interface [polypeptide binding]; other site
926550004641	phosphorylation site [posttranslational modification]
926550004642	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004643	ATP binding site [chemical binding]; other site
926550004644	Mg2+ binding site [ion binding]; other site
926550004645	G-X-G motif; other site
926550004646	FIST N domain; Region: FIST; pfam08495
926550004647	FIST C domain; Region: FIST_C; pfam10442
926550004648	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
926550004649	DPG_synthase is involved in protein N-linked glycosylation; Region: DPG_synthase; cd04188
926550004650	Ligand binding site; other site
926550004651	Ligand binding site; other site
926550004652	Ligand binding site; other site
926550004653	Putative Catalytic site; other site
926550004654	DXD motif; other site
926550004655	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550004656	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550004657	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
926550004658	anti sigma factor interaction site; other site
926550004659	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
926550004660	regulatory phosphorylation site [posttranslational modification]; other site
926550004661	Response regulator receiver domain; Region: Response_reg; pfam00072
926550004662	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004663	active site
926550004664	phosphorylation site [posttranslational modification]
926550004665	intermolecular recognition site; other site
926550004666	dimerization interface [polypeptide binding]; other site
926550004667	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
926550004668	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
926550004669	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
926550004670	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
926550004671	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
926550004672	anti sigma factor interaction site; other site
926550004673	regulatory phosphorylation site [posttranslational modification]; other site
926550004674	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
926550004675	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
926550004676	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
926550004677	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_11; cd13126
926550004678	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550004679	Polysaccharide pyruvyl transferase family protein [Cell wall/membrane/envelope biogenesis]; Region: WcaK; COG2327
926550004680	Polysaccharide pyruvyl transferase; Region: PS_pyruv_trans; cl09156
926550004681	Mannosyltransferase (PIG-V)); Region: Mannosyl_trans2; pfam04188
926550004682	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550004683	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004684	active site
926550004685	phosphorylation site [posttranslational modification]
926550004686	intermolecular recognition site; other site
926550004687	dimerization interface [polypeptide binding]; other site
926550004688	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550004689	DNA binding site [nucleotide binding]
926550004690	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550004691	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
926550004692	DNA methylase; Region: N6_N4_Mtase; cl17433
926550004693	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550004694	Predicted ATPase [General function prediction only]; Region: COG4637
926550004695	Walker A/P-loop; other site
926550004696	ATP binding site [chemical binding]; other site
926550004697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550004698	ABC transporter signature motif; other site
926550004699	Walker B; other site
926550004700	D-loop; other site
926550004701	Domain of unknown function (DUF4276); Region: DUF4276; pfam14103
926550004702	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550004703	TAP-like protein; Region: Abhydrolase_4; pfam08386
926550004704	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550004705	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); Region: PvlArgDC; pfam01862
926550004706	agmatinase; Region: agmatinase; TIGR01230
926550004707	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
926550004708	putative active site [active]
926550004709	Mn binding site [ion binding]; other site
926550004710	Deoxyhypusine synthase; Region: DS; cl00826
926550004711	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
926550004712	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
926550004713	active site
926550004714	substrate binding site [chemical binding]; other site
926550004715	metal binding site [ion binding]; metal-binding site
926550004716	Adenosine specific kinase; Region: Adenosine_kin; pfam04008
926550004717	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
926550004718	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
926550004719	dimer interface [polypeptide binding]; other site
926550004720	active site
926550004721	CoA binding pocket [chemical binding]; other site
926550004722	Acyl-CoA dehydrogenase (ACAD) 10 and 11, N-terminal domain, and similar proteins. This subfamily is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs); Region: ACAD10_11_like; cd05154
926550004723	Phosphotransferase enzyme family; Region: APH; pfam01636
926550004724	putative active site [active]
926550004725	putative substrate binding site [chemical binding]; other site
926550004726	ATP binding site [chemical binding]; other site
926550004727	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926550004728	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550004729	Walker A/P-loop; other site
926550004730	ATP binding site [chemical binding]; other site
926550004731	Q-loop/lid; other site
926550004732	ABC transporter signature motif; other site
926550004733	Walker B; other site
926550004734	D-loop; other site
926550004735	H-loop/switch region; other site
926550004736	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926550004737	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550004738	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550004739	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550004740	TM-ABC transporter signature motif; other site
926550004741	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550004742	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550004743	TM-ABC transporter signature motif; other site
926550004744	Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]; Region: FAA1; COG1022
926550004745	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550004746	Long-chain fatty acid CoA synthetases and Bubblegum-like very long-chain fatty acid CoA synthetases; Region: VL_LC_FACS_like; cd05907
926550004747	acyl-activating enzyme (AAE) consensus motif; other site
926550004748	acyl-activating enzyme (AAE) consensus motif; other site
926550004749	putative AMP binding site [chemical binding]; other site
926550004750	putative active site [active]
926550004751	putative CoA binding site [chemical binding]; other site
926550004752	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550004753	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550004754	Walker A/P-loop; other site
926550004755	ATP binding site [chemical binding]; other site
926550004756	Q-loop/lid; other site
926550004757	ABC transporter signature motif; other site
926550004758	Walker B; other site
926550004759	D-loop; other site
926550004760	H-loop/switch region; other site
926550004761	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550004762	catalytic core [active]
926550004763	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550004764	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_2; cd03814
926550004765	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550004766	NAD(P) binding site [chemical binding]; other site
926550004767	active site
926550004768	Creatinine amidohydrolase; Region: Creatininase; pfam02633
926550004769	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
926550004770	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
926550004771	glutaminase active site [active]
926550004772	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
926550004773	dimer interface [polypeptide binding]; other site
926550004774	active site
926550004775	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
926550004776	dimer interface [polypeptide binding]; other site
926550004777	active site
926550004778	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
926550004779	Malic enzyme, N-terminal domain; Region: malic; pfam00390
926550004780	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
926550004781	putative NAD(P) binding site [chemical binding]; other site
926550004782	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
926550004783	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550004784	dimerization interface [polypeptide binding]; other site
926550004785	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550004786	dimer interface [polypeptide binding]; other site
926550004787	phosphorylation site [posttranslational modification]
926550004788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550004789	ATP binding site [chemical binding]; other site
926550004790	Mg2+ binding site [ion binding]; other site
926550004791	G-X-G motif; other site
926550004792	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550004793	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550004794	active site
926550004795	phosphorylation site [posttranslational modification]
926550004796	intermolecular recognition site; other site
926550004797	dimerization interface [polypeptide binding]; other site
926550004798	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550004799	DNA binding site [nucleotide binding]
926550004800	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
926550004801	multicopper oxidase; Provisional; Region: PRK10965
926550004802	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
926550004803	Predicted membrane protein [Function unknown]; Region: COG3462
926550004804	Short C-terminal domain; Region: SHOCT; pfam09851
926550004805	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
926550004806	Cytochrome c; Region: Cytochrom_C; pfam00034
926550004807	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
926550004808	copper-(or silver)-translocating P-type ATPase; Region: ATPase-IB1_Cu; TIGR01511
926550004809	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550004810	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550004811	motif II; other site
926550004812	galactokinase; Provisional; Region: PRK05322
926550004813	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
926550004814	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
926550004815	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550004816	catalytic core [active]
926550004817	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
926550004818	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
926550004819	N-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_N_like; cd08346
926550004820	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550004821	Zn binding site [ion binding]; other site
926550004822	C-terminal domain of Sphingobium chlorophenolicum 2,6-dichloro-p-hydroquinone 1,2-dioxygenase (PcpA), and similar proteins; Region: PcpA_C_like; cd08347
926550004823	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550004824	Zn binding site [ion binding]; other site
926550004825	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926550004826	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_6; cd12165
926550004827	putative ligand binding site [chemical binding]; other site
926550004828	NAD binding site [chemical binding]; other site
926550004829	dimer interface [polypeptide binding]; other site
926550004830	putative catalytic site [active]
926550004831	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926550004832	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
926550004833	metal binding site [ion binding]; metal-binding site
926550004834	dimer interface [polypeptide binding]; other site
926550004835	Protein of unknown function (DUF3108); Region: DUF3108; pfam11306
926550004836	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550004837	nucleotide binding site [chemical binding]; other site
926550004838	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
926550004839	active site
926550004840	substrate binding site [chemical binding]; other site
926550004841	activation loop (A-loop); other site
926550004842	Predicted ATPase [General function prediction only]; Region: COG3903
926550004843	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550004844	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926550004845	binding surface
926550004846	TPR motif; other site
926550004847	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
926550004848	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
926550004849	phosphopeptide binding site; other site
926550004850	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550004851	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550004852	DNA binding site [nucleotide binding]
926550004853	Right handed beta helix region; Region: Beta_helix; pfam13229
926550004854	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
926550004855	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926550004856	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550004857	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
926550004858	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926550004859	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550004860	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
926550004861	IMP binding site; other site
926550004862	dimer interface [polypeptide binding]; other site
926550004863	interdomain contacts; other site
926550004864	partial ornithine binding site; other site
926550004865	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
926550004866	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
926550004867	putative RNA binding site [nucleotide binding]; other site
926550004868	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550004869	S-adenosylmethionine binding site [chemical binding]; other site
926550004870	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
926550004871	putative active site [active]
926550004872	putative CoA binding site [chemical binding]; other site
926550004873	nudix motif; other site
926550004874	metal binding site [ion binding]; metal-binding site
926550004875	Glycoside hydrolase families 71, 99, and related domains; Region: GH99_GH71_like; cl01529
926550004876	ligand binding site [chemical binding]; other site
926550004877	putative catalytic site [active]
926550004878	Bacterial SH3 domain; Region: SH3_3; cl17532
926550004879	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550004880	active site
926550004881	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550004882	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550004883	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550004884	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550004885	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
926550004886	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
926550004887	5S rRNA interface [nucleotide binding]; other site
926550004888	CTC domain interface [polypeptide binding]; other site
926550004889	L16 interface [polypeptide binding]; other site
926550004890	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
926550004891	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
926550004892	active site
926550004893	catalytic site [active]
926550004894	putative DNA binding site [nucleotide binding]; other site
926550004895	GIY-YIG motif/motif A; other site
926550004896	metal binding site [ion binding]; metal-binding site
926550004897	UvrB/uvrC motif; Region: UVR; pfam02151
926550004898	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
926550004899	Helix-hairpin-helix motif; Region: HHH; pfam00633
926550004900	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550004901	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550004902	ligand binding site [chemical binding]; other site
926550004903	flexible hinge region; other site
926550004904	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550004905	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550004906	ligand binding site [chemical binding]; other site
926550004907	flexible hinge region; other site
926550004908	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550004909	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550004910	ligand binding site [chemical binding]; other site
926550004911	Bacterial PH domain; Region: DUF304; pfam03703
926550004912	Bacterial PH domain; Region: DUF304; pfam03703
926550004913	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
926550004914	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550004915	active site
926550004916	metal binding site [ion binding]; metal-binding site
926550004917	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
926550004918	ATP-NAD kinase; Region: NAD_kinase; pfam01513
926550004919	B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction; Region: BBOX; cl00034
926550004920	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550004921	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550004922	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550004923	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550004924	Protein of unknown function (DUF433); Region: DUF433; pfam04255
926550004925	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
926550004926	elongation factor Tu; Reviewed; Region: PRK00049
926550004927	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
926550004928	G1 box; other site
926550004929	GEF interaction site [polypeptide binding]; other site
926550004930	GTP/Mg2+ binding site [chemical binding]; other site
926550004931	Switch I region; other site
926550004932	G2 box; other site
926550004933	G3 box; other site
926550004934	Switch II region; other site
926550004935	G4 box; other site
926550004936	G5 box; other site
926550004937	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
926550004938	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
926550004939	Antibiotic Binding Site [chemical binding]; other site
926550004940	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
926550004941	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
926550004942	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
926550004943	putative homodimer interface [polypeptide binding]; other site
926550004944	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
926550004945	heterodimer interface [polypeptide binding]; other site
926550004946	homodimer interface [polypeptide binding]; other site
926550004947	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
926550004948	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
926550004949	putative thiostrepton binding site; other site
926550004950	23S rRNA interface [nucleotide binding]; other site
926550004951	L7/L12 interface [polypeptide binding]; other site
926550004952	L25 interface [polypeptide binding]; other site
926550004953	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
926550004954	mRNA/rRNA interface [nucleotide binding]; other site
926550004955	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
926550004956	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
926550004957	dimerization interface [polypeptide binding]; other site
926550004958	domain crossover interface; other site
926550004959	redox-dependent activation switch; other site
926550004960	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
926550004961	23S rRNA interface [nucleotide binding]; other site
926550004962	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
926550004963	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
926550004964	core dimer interface [polypeptide binding]; other site
926550004965	peripheral dimer interface [polypeptide binding]; other site
926550004966	L10 interface [polypeptide binding]; other site
926550004967	L11 interface [polypeptide binding]; other site
926550004968	putative EF-Tu interaction site [polypeptide binding]; other site
926550004969	putative EF-G interaction site [polypeptide binding]; other site
926550004970	DNA polymerase III subunit delta'; Validated; Region: PRK05564
926550004971	DNA polymerase III subunit delta'; Validated; Region: PRK08485
926550004972	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
926550004973	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
926550004974	Cysteine-rich domain; Region: CCG; pfam02754
926550004975	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926550004976	Cysteine-rich domain; Region: CCG; pfam02754
926550004977	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926550004978	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
926550004979	active site
926550004980	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
926550004981	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
926550004982	dimer interface [polypeptide binding]; other site
926550004983	ssDNA binding site [nucleotide binding]; other site
926550004984	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550004985	haloacid dehalogenase superfamily protein; Provisional; Region: PRK14562
926550004986	Translin family; Region: Translin; cl00957
926550004987	Putative periplasmic protein kinase ArgK and related GTPases of G3E family [Amino acid transport and metabolism]; Region: ArgK; COG1703
926550004988	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
926550004989	Walker A; other site
926550004990	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
926550004991	B12 binding site [chemical binding]; other site
926550004992	cobalt ligand [ion binding]; other site
926550004993	Putative phosphatase regulatory subunit; Region: CBM_21; pfam03370
926550004994	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
926550004995	putative catalytic site [active]
926550004996	putative metal binding site [ion binding]; other site
926550004997	putative phosphate binding site [ion binding]; other site
926550004998	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
926550004999	PLD-like domain; Region: PLDc_2; pfam13091
926550005000	putative active site [active]
926550005001	catalytic site [active]
926550005002	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
926550005003	PLD-like domain; Region: PLDc_2; pfam13091
926550005004	putative active site [active]
926550005005	catalytic site [active]
926550005006	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
926550005007	Helix-hairpin-helix motif; Region: HHH; pfam00633
926550005008	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
926550005009	Poly(hydroxyalcanoate) granule associated protein (phasin); Region: Phasin; cl07863
926550005010	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
926550005011	TMAO/DMSO reductase; Reviewed; Region: PRK05363
926550005012	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cl00199
926550005013	Moco binding site; other site
926550005014	metal coordination site [ion binding]; other site
926550005015	phytoene desaturase; Region: crtI_fam; TIGR02734
926550005016	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550005017	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550005018	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550005019	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550005020	active site
926550005021	catalytic tetrad [active]
926550005022	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
926550005023	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
926550005024	active site pocket [active]
926550005025	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926550005026	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550005027	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550005028	classical (c) SDRs; Region: SDR_c; cd05233
926550005029	NAD(P) binding site [chemical binding]; other site
926550005030	active site
926550005031	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550005032	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550005033	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550005034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005035	dimer interface [polypeptide binding]; other site
926550005036	conserved gate region; other site
926550005037	putative PBP binding loops; other site
926550005038	ABC-ATPase subunit interface; other site
926550005039	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550005040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005041	dimer interface [polypeptide binding]; other site
926550005042	conserved gate region; other site
926550005043	putative PBP binding loops; other site
926550005044	ABC-ATPase subunit interface; other site
926550005045	Transcriptional regulators [Transcription]; Region: GntR; COG1802
926550005046	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550005047	DNA-binding site [nucleotide binding]; DNA binding site
926550005048	FCD domain; Region: FCD; pfam07729
926550005049	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550005050	Ligand Binding Site [chemical binding]; other site
926550005051	isocitrate lyase; Provisional; Region: PRK15063
926550005052	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
926550005053	tetramer interface [polypeptide binding]; other site
926550005054	active site
926550005055	Mg2+/Mn2+ binding site [ion binding]; other site
926550005056	Probable zinc-binding domain; Region: zf-trcl; pfam13451
926550005057	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926550005058	DNA-binding site [nucleotide binding]; DNA binding site
926550005059	RNA-binding motif; other site
926550005060	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
926550005061	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
926550005062	ligand binding site; other site
926550005063	oligomer interface; other site
926550005064	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
926550005065	dimer interface [polypeptide binding]; other site
926550005066	N-terminal domain interface [polypeptide binding]; other site
926550005067	sulfate 1 binding site; other site
926550005068	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
926550005069	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
926550005070	ligand binding site; other site
926550005071	oligomer interface; other site
926550005072	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
926550005073	dimer interface [polypeptide binding]; other site
926550005074	N-terminal domain interface [polypeptide binding]; other site
926550005075	sulfate 1 binding site; other site
926550005076	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550005077	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550005078	S-adenosylmethionine binding site [chemical binding]; other site
926550005079	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926550005080	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
926550005081	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
926550005082	active site
926550005083	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
926550005084	protein binding site [polypeptide binding]; other site
926550005085	C-terminal processing peptidase family S41; Region: Peptidase_S41; cd06567
926550005086	Active site serine [active]
926550005087	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550005088	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550005089	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550005090	NAD(P) binding site [chemical binding]; other site
926550005091	active site
926550005092	CHAT domain; Region: CHAT; cl17868
926550005093	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926550005094	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
926550005095	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
926550005096	periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily; Region: dsbE; TIGR00385
926550005097	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926550005098	catalytic residues [active]
926550005099	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
926550005100	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550005101	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550005102	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
926550005103	Transglycosylase; Region: Transgly; pfam00912
926550005104	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
926550005105	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
926550005106	DPG_synthase is involved in protein N-linked glycosylation; Region: DPG_synthase; cd04188
926550005107	Ligand binding site; other site
926550005108	Ligand binding site; other site
926550005109	Ligand binding site; other site
926550005110	Putative Catalytic site; other site
926550005111	DXD motif; other site
926550005112	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
926550005113	Ligand binding site [chemical binding]; other site
926550005114	Electron transfer flavoprotein domain; Region: ETF; pfam01012
926550005115	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
926550005116	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
926550005117	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
926550005118	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
926550005119	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
926550005120	predicted active site [active]
926550005121	catalytic triad [active]
926550005122	probable F420-dependent oxidoreductase, Rv3093c family; Region: F420_Rv3093c; TIGR03841
926550005123	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
926550005124	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
926550005125	Domain of unknown function (DUF4350); Region: DUF4350; pfam14258
926550005126	MoxR-like ATPases [General function prediction only]; Region: COG0714
926550005127	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550005128	Walker A motif; other site
926550005129	ATP binding site [chemical binding]; other site
926550005130	Walker B motif; other site
926550005131	arginine finger; other site
926550005132	glyoxylate reductase; Reviewed; Region: PRK13243
926550005133	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
926550005134	dimerization interface [polypeptide binding]; other site
926550005135	ligand binding site [chemical binding]; other site
926550005136	NADP binding site [chemical binding]; other site
926550005137	catalytic site [active]
926550005138	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550005139	UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs; Region: UGD_SDR_e; cd05230
926550005140	NAD binding site [chemical binding]; other site
926550005141	putative substrate binding site 2 [chemical binding]; other site
926550005142	putative substrate binding site 1 [chemical binding]; other site
926550005143	active site
926550005144	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
926550005145	Thiamine pyrophosphokinase; Region: TPK; cd07995
926550005146	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
926550005147	active site
926550005148	dimerization interface [polypeptide binding]; other site
926550005149	thiamine binding site [chemical binding]; other site
926550005150	ADP-ribosylglycohydrolase; Region: ADP_ribosyl_GH; pfam03747
926550005151	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550005152	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550005153	TM-ABC transporter signature motif; other site
926550005154	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550005155	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550005156	TM-ABC transporter signature motif; other site
926550005157	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
926550005158	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550005159	Walker A/P-loop; other site
926550005160	ATP binding site [chemical binding]; other site
926550005161	Q-loop/lid; other site
926550005162	ABC transporter signature motif; other site
926550005163	Walker B; other site
926550005164	D-loop; other site
926550005165	H-loop/switch region; other site
926550005166	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550005167	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
926550005168	Periplasmic binding component of a family of basic membrane lipoproteins from Borrelia and various putative lipoproteins from other bacteria; Region: PBP1_BmpA_like; cd06304
926550005169	ligand binding site [chemical binding]; other site
926550005170	PPOX class probable F420-dependent enzyme, Rv2061 family; Region: Rv2061_F420; TIGR03666
926550005171	GTPase Era; Reviewed; Region: era; PRK00089
926550005172	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
926550005173	G1 box; other site
926550005174	GTP/Mg2+ binding site [chemical binding]; other site
926550005175	Switch I region; other site
926550005176	G2 box; other site
926550005177	Switch II region; other site
926550005178	G3 box; other site
926550005179	G4 box; other site
926550005180	G5 box; other site
926550005181	KH domain; Region: KH_2; pfam07650
926550005182	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
926550005183	putative active site [active]
926550005184	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
926550005185	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
926550005186	prolyl-tRNA synthetase; Provisional; Region: PRK09194
926550005187	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
926550005188	dimer interface [polypeptide binding]; other site
926550005189	motif 1; other site
926550005190	active site
926550005191	motif 2; other site
926550005192	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
926550005193	putative deacylase active site [active]
926550005194	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
926550005195	active site
926550005196	motif 3; other site
926550005197	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
926550005198	anticodon binding site; other site
926550005199	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550005200	catalytic residues [active]
926550005201	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
926550005202	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
926550005203	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
926550005204	acyl-activating enzyme (AAE) consensus motif; other site
926550005205	putative AMP binding site [chemical binding]; other site
926550005206	putative active site [active]
926550005207	putative CoA binding site [chemical binding]; other site
926550005208	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
926550005209	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
926550005210	twin arginine-targeting protein translocase TatB; Region: tatB; TIGR01410
926550005211	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
926550005212	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
926550005213	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
926550005214	NAD(P) binding site [chemical binding]; other site
926550005215	homotetramer interface [polypeptide binding]; other site
926550005216	homodimer interface [polypeptide binding]; other site
926550005217	active site
926550005218	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
926550005219	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
926550005220	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
926550005221	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550005222	active site
926550005223	NTP binding site [chemical binding]; other site
926550005224	metal binding triad [ion binding]; metal-binding site
926550005225	antibiotic binding site [chemical binding]; other site
926550005226	FecR protein; Region: FecR; pfam04773
926550005227	TPR repeat; Region: TPR_11; pfam13414
926550005228	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550005229	binding surface
926550005230	TPR motif; other site
926550005231	Domain of unknown function (DUF307); Region: DUF307; pfam03733
926550005232	Domain of unknown function (DUF307); Region: DUF307; pfam03733
926550005233	Predicted transcriptional regulator [Transcription]; Region: COG2378
926550005234	WYL domain; Region: WYL; pfam13280
926550005235	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cl09909
926550005236	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
926550005237	CRISPR-associated autoregulator DevR family; Region: cas_MJ0381; TIGR01875
926550005238	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cd09693
926550005239	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
926550005240	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
926550005241	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
926550005242	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
926550005243	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-II-III; cd09634
926550005244	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
926550005245	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550005246	potential frameshift: common BLAST hit: gi|302388672|ref|YP_003824493.1| transposase IS116/IS110/IS902 family protein
926550005247	Transposase IS116/IS110/IS902 family; Region: Transposase_20; pfam02371
926550005248	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926550005249	Transposase; Region: DEDD_Tnp_IS110; pfam01548
926550005250	isopentenyl pyrophosphate isomerase; Provisional; Region: PRK05437
926550005251	Isopentenyl-diphosphate:dimethylallyl diphosphate isomerase type 2 (IDI-2) FMN-binding domain. Two types of IDIs have been characterized at present. The long known IDI-1 is only dependent on divalent metals for activity, whereas IDI-2 requires a metal; Region: IDI-2_FMN; cd02811
926550005252	homotetramer interface [polypeptide binding]; other site
926550005253	FMN binding site [chemical binding]; other site
926550005254	homodimer contacts [polypeptide binding]; other site
926550005255	putative active site [active]
926550005256	putative substrate binding site [chemical binding]; other site
926550005257	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
926550005258	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
926550005259	substrate binding pocket [chemical binding]; other site
926550005260	chain length determination region; other site
926550005261	substrate-Mg2+ binding site; other site
926550005262	catalytic residues [active]
926550005263	aspartate-rich region 1; other site
926550005264	active site lid residues [active]
926550005265	aspartate-rich region 2; other site
926550005266	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
926550005267	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550005268	E3 interaction surface; other site
926550005269	lipoyl attachment site [posttranslational modification]; other site
926550005270	e3 binding domain; Region: E3_binding; pfam02817
926550005271	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550005272	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550005273	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926550005274	alpha subunit interface [polypeptide binding]; other site
926550005275	TPP binding site [chemical binding]; other site
926550005276	heterodimer interface [polypeptide binding]; other site
926550005277	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550005278	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926550005279	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550005280	tetramer interface [polypeptide binding]; other site
926550005281	TPP-binding site [chemical binding]; other site
926550005282	heterodimer interface [polypeptide binding]; other site
926550005283	phosphorylation loop region [posttranslational modification]
926550005284	Cys/Met metabolism PLP-dependent enzyme; Region: Cys_Met_Meta_PP; pfam01053
926550005285	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926550005286	homodimer interface [polypeptide binding]; other site
926550005287	substrate-cofactor binding pocket; other site
926550005288	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550005289	catalytic residue [active]
926550005290	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550005291	S-adenosylmethionine binding site [chemical binding]; other site
926550005292	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550005293	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550005294	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550005295	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550005296	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550005297	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550005298	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550005299	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550005300	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
926550005301	active site
926550005302	FMN binding site [chemical binding]; other site
926550005303	substrate binding site [chemical binding]; other site
926550005304	putative catalytic residue [active]
926550005305	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926550005306	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926550005307	inhibitor site; inhibition site
926550005308	active site
926550005309	dimer interface [polypeptide binding]; other site
926550005310	catalytic residue [active]
926550005311	Transcriptional regulators [Transcription]; Region: FadR; COG2186
926550005312	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550005313	DNA-binding site [nucleotide binding]; DNA binding site
926550005314	FCD domain; Region: FCD; pfam07729
926550005315	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550005316	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550005317	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005318	dimer interface [polypeptide binding]; other site
926550005319	conserved gate region; other site
926550005320	putative PBP binding loops; other site
926550005321	ABC-ATPase subunit interface; other site
926550005322	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550005323	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005324	dimer interface [polypeptide binding]; other site
926550005325	conserved gate region; other site
926550005326	putative PBP binding loops; other site
926550005327	ABC-ATPase subunit interface; other site
926550005328	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG); Region: Caa3_CtaG; pfam09678
926550005329	Peptidase M14 Carboxypeptidase T-like subfamily; Region: M14_CPT_like; cd06226
926550005330	putative active site [active]
926550005331	Zn binding site [ion binding]; other site
926550005332	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926550005333	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550005334	active site
926550005335	Protein of unknown function (DUF3179); Region: DUF3179; pfam11376
926550005336	Protein of unknown function (DUF3179); Region: DUF3179; pfam11376
926550005337	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926550005338	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926550005339	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550005340	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
926550005341	active site
926550005342	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
926550005343	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
926550005344	active site
926550005345	catalytic site [active]
926550005346	substrate binding site [chemical binding]; other site
926550005347	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
926550005348	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
926550005349	putative Mg++ binding site [ion binding]; other site
926550005350	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
926550005351	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
926550005352	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
926550005353	ATP-binding site [chemical binding]; other site
926550005354	Sugar specificity; other site
926550005355	Pyrimidine base specificity; other site
926550005356	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550005357	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550005358	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
926550005359	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550005360	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550005361	RecX family; Region: RecX; cl00936
926550005362	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550005363	Coenzyme A binding pocket [chemical binding]; other site
926550005364	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926550005365	Uncharacterized subgroup of the nitrilase superfamily; some members of this subgroup have an N-terminal RimI domain (class 12 nitrilases); Region: nitrilase_Rim1_like; cd07574
926550005366	putative active site [active]
926550005367	catalytic triad [active]
926550005368	putative dimer interface [polypeptide binding]; other site
926550005369	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926550005370	carboxyltransferase (CT) interaction site; other site
926550005371	biotinylation site [posttranslational modification]; other site
926550005372	Citrate lyase beta subunit [Carbohydrate transport and metabolism]; Region: CitE; COG2301
926550005373	FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2  has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal...; Region: FkbR2; cd03451
926550005374	putative active site [active]
926550005375	putative catalytic site [active]
926550005376	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550005377	Uncharacterized conserved protein [Function unknown]; Region: COG2835
926550005378	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
926550005379	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
926550005380	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550005381	motif II; other site
926550005382	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926550005383	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926550005384	Yqey-like protein; Region: YqeY; cl17540
926550005385	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
926550005386	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
926550005387	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550005388	Zn2+ binding site [ion binding]; other site
926550005389	Mg2+ binding site [ion binding]; other site
926550005390	Uncharacterized protein family UPF0054; Region: UPF0054; pfam02130
926550005391	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
926550005392	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; pfam00486
926550005393	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550005394	Predicted ATPase [General function prediction only]; Region: COG3899
926550005395	AAA ATPase domain; Region: AAA_16; pfam13191
926550005396	Walker A motif; other site
926550005397	ATP binding site [chemical binding]; other site
926550005398	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
926550005399	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
926550005400	N-acetyl-D-glucosamine binding site [chemical binding]; other site
926550005401	catalytic residue [active]
926550005402	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
926550005403	putative active site [active]
926550005404	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
926550005405	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550005406	peptide binding site [polypeptide binding]; other site
926550005407	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550005408	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550005409	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005410	putative PBP binding loops; other site
926550005411	dimer interface [polypeptide binding]; other site
926550005412	ABC-ATPase subunit interface; other site
926550005413	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
926550005414	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005415	putative PBP binding loops; other site
926550005416	dimer interface [polypeptide binding]; other site
926550005417	ABC-ATPase subunit interface; other site
926550005418	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550005419	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550005420	DNA binding site [nucleotide binding]
926550005421	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
926550005422	AMP binding site [chemical binding]; other site
926550005423	metal binding site [ion binding]; metal-binding site
926550005424	active site
926550005425	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
926550005426	Transcriptional regulator [Transcription]; Region: IclR; COG1414
926550005427	Bacterial transcriptional regulator; Region: IclR; pfam01614
926550005428	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
926550005429	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
926550005430	active site pocket [active]
926550005431	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550005432	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
926550005433	putative NAD(P) binding site [chemical binding]; other site
926550005434	catalytic Zn binding site [ion binding]; other site
926550005435	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
926550005436	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
926550005437	intersubunit interface [polypeptide binding]; other site
926550005438	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
926550005439	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
926550005440	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
926550005441	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550005442	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
926550005443	catalytic triad [active]
926550005444	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
926550005445	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
926550005446	homodimer interface [polypeptide binding]; other site
926550005447	Walker A motif; other site
926550005448	ATP binding site [chemical binding]; other site
926550005449	hydroxycobalamin binding site [chemical binding]; other site
926550005450	Walker B motif; other site
926550005451	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
926550005452	dimer interface [polypeptide binding]; other site
926550005453	[2Fe-2S] cluster binding site [ion binding]; other site
926550005454	cobaltochelatase subunit CobN; Reviewed; Region: cobN; PRK05989
926550005455	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
926550005456	CobN subunit of cobaltochelatase, bchH and chlH subunits of magnesium chelatases, and similar proteins; Region: CobN_like; cd10150
926550005457	Predicted GTPase [General function prediction only]; Region: COG2403
926550005458	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550005459	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550005460	active site
926550005461	NTP binding site [chemical binding]; other site
926550005462	metal binding triad [ion binding]; metal-binding site
926550005463	antibiotic binding site [chemical binding]; other site
926550005464	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550005465	Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism]; Region: GcvT; COG0404
926550005466	Sarcosine oxidase, gamma subunit family; Region: SoxG; cl01893
926550005467	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
926550005468	putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; Provisional; Region: PRK14498
926550005469	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
926550005470	dimer interface [polypeptide binding]; other site
926550005471	putative functional site; other site
926550005472	putative MPT binding site; other site
926550005473	PBP superfamily domain; Region: PBP_like; pfam12727
926550005474	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
926550005475	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
926550005476	dimer interface [polypeptide binding]; other site
926550005477	putative functional site; other site
926550005478	putative MPT binding site; other site
926550005479	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
926550005480	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
926550005481	GTP binding site; other site
926550005482	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
926550005483	active site pocket [active]
926550005484	oxyanion hole [active]
926550005485	catalytic triad [active]
926550005486	active site nucleophile [active]
926550005487	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
926550005488	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926550005489	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550005490	DNA binding residues [nucleotide binding]
926550005491	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926550005492	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550005493	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550005494	nucleotide binding site [chemical binding]; other site
926550005495	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550005496	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550005497	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005498	dimer interface [polypeptide binding]; other site
926550005499	conserved gate region; other site
926550005500	putative PBP binding loops; other site
926550005501	ABC-ATPase subunit interface; other site
926550005502	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005503	dimer interface [polypeptide binding]; other site
926550005504	conserved gate region; other site
926550005505	putative PBP binding loops; other site
926550005506	ABC-ATPase subunit interface; other site
926550005507	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926550005508	Hexulose-6-phosphate isomerase (PHI). PHI is a member of the SIS (Sugar ISomerase domain) superfamily. In the ribulose monophosphate pathway of formaldehyde fixation, hexulose-6-phosphate synthase catalyzes the condensation of ribulose-5-phosphate with...; Region: SIS_PHI; cd05005
926550005509	tetramer interface [polypeptide binding]; other site
926550005510	active site
926550005511	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550005512	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550005513	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
926550005514	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
926550005515	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
926550005516	catalytic site [active]
926550005517	subunit interface [polypeptide binding]; other site
926550005518	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550005519	active site
926550005520	NTP binding site [chemical binding]; other site
926550005521	metal binding triad [ion binding]; metal-binding site
926550005522	antibiotic binding site [chemical binding]; other site
926550005523	HEPN domain; Region: HEPN; pfam05168
926550005524	Trimethylamine methyltransferase (MTTB); Region: MTTB; cl15385
926550005525	Predicted phosphoesterases, related to the Icc protein [General function prediction only]; Region: COG2129
926550005526	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926550005527	active site
926550005528	metal binding site [ion binding]; metal-binding site
926550005529	Thermus thermophilus TTHA0053 and related proteins, metallophosphatase domain; Region: MPP_TTHA0053; cd07403
926550005530	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550005531	Zn2+ binding site [ion binding]; other site
926550005532	Mg2+ binding site [ion binding]; other site
926550005533	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
926550005534	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
926550005535	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550005536	FeS/SAM binding site; other site
926550005537	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
926550005538	DNA binding residues [nucleotide binding]
926550005539	Helicase conserved C-terminal domain; Region: Helicase_C_3; pfam13625
926550005540	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550005541	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
926550005542	peptide binding site [polypeptide binding]; other site
926550005543	dimer interface [polypeptide binding]; other site
926550005544	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550005545	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005546	dimer interface [polypeptide binding]; other site
926550005547	conserved gate region; other site
926550005548	putative PBP binding loops; other site
926550005549	ABC-ATPase subunit interface; other site
926550005550	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550005551	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
926550005552	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005553	dimer interface [polypeptide binding]; other site
926550005554	conserved gate region; other site
926550005555	putative PBP binding loops; other site
926550005556	ABC-ATPase subunit interface; other site
926550005557	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
926550005558	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
926550005559	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550005560	catalytic core [active]
926550005561	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
926550005562	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926550005563	AAK_NAGK-like: N-Acetyl-L-glutamate kinase (NAGK)-like . Included in this CD are the Escherichia coli and Pseudomonas aeruginosa type NAGKs which catalyze the phosphorylation of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine...; Region: AAK_NAGK-like; cd04238
926550005564	nucleotide binding site [chemical binding]; other site
926550005565	N-acetyl-L-glutamate binding site [chemical binding]; other site
926550005566	acetylornithine aminotransferase; Provisional; Region: PRK02627
926550005567	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550005568	inhibitor-cofactor binding pocket; inhibition site
926550005569	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550005570	catalytic residue [active]
926550005571	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550005572	Coenzyme A binding pocket [chemical binding]; other site
926550005573	Plasmid pRiA4b ORF-3-like protein; Region: PRiA4_ORF3; pfam07929
926550005574	Protein of unknown function (DUF1349); Region: DUF1349; pfam07081
926550005575	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
926550005576	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926550005577	Alpha-crystallin domain (ACD) of alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain  (ACD). sHsps are generally...; Region: ACD_sHsps-like; cd06464
926550005578	putative dimer interface [polypeptide binding]; other site
926550005579	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
926550005580	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
926550005581	NADP-binding site; other site
926550005582	homotetramer interface [polypeptide binding]; other site
926550005583	substrate binding site [chemical binding]; other site
926550005584	homodimer interface [polypeptide binding]; other site
926550005585	active site
926550005586	Uncharacterized ACR, YhhQ family COG1738; Region: DUF165; pfam02592
926550005587	Predicted permease; Region: DUF318; pfam03773
926550005588	TIGR03943 family protein; Region: TIGR03943
926550005589	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550005590	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550005591	Uncharacterized conserved protein [Function unknown]; Region: COG5276
926550005592	LVIVD repeat; Region: LVIVD; pfam08309
926550005593	LVIVD repeat; Region: LVIVD; pfam08309
926550005594	LVIVD repeat; Region: LVIVD; pfam08309
926550005595	LVIVD repeat; Region: LVIVD; pfam08309
926550005596	LVIVD repeat; Region: LVIVD; pfam08309
926550005597	LVIVD repeat; Region: LVIVD; pfam08309
926550005598	LVIVD repeat; Region: LVIVD; pfam08309
926550005599	LVIVD repeat; Region: LVIVD; pfam08309
926550005600	LVIVD repeat; Region: LVIVD; pfam08309
926550005601	LVIVD repeat; Region: LVIVD; pfam08309
926550005602	LVIVD repeat; Region: LVIVD; pfam08309
926550005603	LVIVD repeat; Region: LVIVD; pfam08309
926550005604	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550005605	Winged helix-turn helix; Region: HTH_29; pfam13551
926550005606	Helix-turn-helix domain; Region: HTH_28; pfam13518
926550005607	Homeodomain-like domain; Region: HTH_32; pfam13565
926550005608	KTSC domain; Region: KTSC; pfam13619
926550005609	HD supefamily hydrolase [General function prediction only]; Region: COG3294
926550005610	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cl17503
926550005611	4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit; Region: HpaG-C-term; TIGR02303
926550005612	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926550005613	ornithine carbamoyltransferase; Provisional; Region: PRK00779
926550005614	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
926550005615	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
926550005616	Uncharacterized conserved protein [Function unknown]; Region: COG1624
926550005617	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
926550005618	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
926550005619	YbbR-like protein; Region: YbbR; pfam07949
926550005620	GTP-binding protein Der; Reviewed; Region: PRK00093
926550005621	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
926550005622	G1 box; other site
926550005623	GTP/Mg2+ binding site [chemical binding]; other site
926550005624	Switch I region; other site
926550005625	G2 box; other site
926550005626	Switch II region; other site
926550005627	G3 box; other site
926550005628	G4 box; other site
926550005629	G5 box; other site
926550005630	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
926550005631	G1 box; other site
926550005632	GTP/Mg2+ binding site [chemical binding]; other site
926550005633	Switch I region; other site
926550005634	G2 box; other site
926550005635	G3 box; other site
926550005636	Switch II region; other site
926550005637	G4 box; other site
926550005638	G5 box; other site
926550005639	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
926550005640	Peptidase family M28; Region: Peptidase_M28; pfam04389
926550005641	metal binding site [ion binding]; metal-binding site
926550005642	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550005643	S-adenosylmethionine binding site [chemical binding]; other site
926550005644	homoserine O-acetyltransferase; Provisional; Region: metX; PRK00175
926550005645	homoserine O-acetyltransferase; Region: homoserO_Ac_trn; TIGR01392
926550005646	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
926550005647	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926550005648	homodimer interface [polypeptide binding]; other site
926550005649	substrate-cofactor binding pocket; other site
926550005650	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550005651	catalytic residue [active]
926550005652	cxxc_20_cxxc protein; Region: cxxc_20_cxxc; TIGR04104
926550005653	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550005654	substrate binding site [chemical binding]; other site
926550005655	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550005656	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550005657	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550005658	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550005659	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005660	dimer interface [polypeptide binding]; other site
926550005661	conserved gate region; other site
926550005662	putative PBP binding loops; other site
926550005663	ABC-ATPase subunit interface; other site
926550005664	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550005665	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550005666	Walker A/P-loop; other site
926550005667	ATP binding site [chemical binding]; other site
926550005668	Q-loop/lid; other site
926550005669	ABC transporter signature motif; other site
926550005670	Walker B; other site
926550005671	D-loop; other site
926550005672	H-loop/switch region; other site
926550005673	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550005674	ABC transporter; Region: ABC_tran; pfam00005
926550005675	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550005676	Q-loop/lid; other site
926550005677	ABC transporter signature motif; other site
926550005678	Walker B; other site
926550005679	D-loop; other site
926550005680	H-loop/switch region; other site
926550005681	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
926550005682	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550005683	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550005684	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550005685	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550005686	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550005687	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550005688	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
926550005689	Sulfatase; Region: Sulfatase; pfam00884
926550005690	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550005691	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550005692	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550005693	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926550005694	Metal-binding active site; metal-binding site
926550005695	DoxX; Region: DoxX; cl17842
926550005696	Predicted ring-cleavage extradiol dioxygenase [General function prediction only]; Region: COG2514
926550005697	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
926550005698	active site
926550005699	metal binding site [ion binding]; metal-binding site
926550005700	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
926550005701	active site
926550005702	Predicted transcriptional regulators [Transcription]; Region: COG1733
926550005703	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550005704	dimerization interface [polypeptide binding]; other site
926550005705	putative DNA binding site [nucleotide binding]; other site
926550005706	putative Zn2+ binding site [ion binding]; other site
926550005707	MFS/sugar transport protein; Region: MFS_2; pfam13347
926550005708	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550005709	putative substrate translocation pore; other site
926550005710	Thermus thermophiles TTHB029 and similar proteins; Region: YdjC_TTHB029_like; cd10802
926550005711	putative active site [active]
926550005712	YdjC motif; other site
926550005713	Mg binding site [ion binding]; other site
926550005714	homodimer interface [polypeptide binding]; other site
926550005715	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
926550005716	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
926550005717	active site
926550005718	HIGH motif; other site
926550005719	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
926550005720	active site
926550005721	KMSKS motif; other site
926550005722	glutaminyl-tRNA synthetase/YqeY domain fusion protein; Provisional; Region: PRK14703
926550005723	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926550005724	active site
926550005725	HIGH motif; other site
926550005726	nucleotide binding site [chemical binding]; other site
926550005727	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
926550005728	KMSKS motif; other site
926550005729	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
926550005730	GatB domain; Region: GatB_Yqey; smart00845
926550005731	Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility; Region: MEMO_like; cd07361
926550005732	putative ligand binding pocket/active site [active]
926550005733	putative metal binding site [ion binding]; other site
926550005734	Domain of unknown function (DUF3524); Region: DUF3524; pfam12038
926550005735	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550005736	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550005737	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
926550005738	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
926550005739	catalytic residues [active]
926550005740	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
926550005741	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
926550005742	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
926550005743	phosphoenolpyruvate synthase; Validated; Region: PRK06241
926550005744	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
926550005745	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
926550005746	putative dimer interface [polypeptide binding]; other site
926550005747	active site pocket [active]
926550005748	putative cataytic base [active]
926550005749	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
926550005750	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
926550005751	Ligand binding site; other site
926550005752	Putative Catalytic site; other site
926550005753	DXD motif; other site
926550005754	Lamin Tail Domain; Region: LTD; pfam00932
926550005755	Lamin Tail Domain; Region: LTD; pfam00932
926550005756	Family description; Region: VCBS; pfam13517
926550005757	Family description; Region: VCBS; pfam13517
926550005758	Family description; Region: VCBS; pfam13517
926550005759	Family description; Region: VCBS; pfam13517
926550005760	Family description; Region: VCBS; pfam13517
926550005761	Family description; Region: VCBS; pfam13517
926550005762	Family description; Region: VCBS; pfam13517
926550005763	Lamin Tail Domain; Region: LTD; pfam00932
926550005764	Lamin Tail Domain; Region: LTD; pfam00932
926550005765	CotH protein; Region: CotH; pfam08757
926550005766	Lamin Tail Domain; Region: LTD; pfam00932
926550005767	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
926550005768	Sulfate transporter family; Region: Sulfate_transp; pfam00916
926550005769	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
926550005770	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
926550005771	amidase catalytic site [active]
926550005772	Zn binding residues [ion binding]; other site
926550005773	substrate binding site [chemical binding]; other site
926550005774	Uncharacterized conserved protein [Function unknown]; Region: COG1359
926550005775	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
926550005776	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_3; pfam13738
926550005777	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550005778	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
926550005779	MviN-like protein; Region: MVIN; pfam03023
926550005780	DNA methylase; Region: N6_N4_Mtase; cl17433
926550005781	Restriction endonuclease BsobI; Region: Endonuc-BsobI; pfam09194
926550005782	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM...; Region: MM_CoA_mutase_ICM_like; cd03680
926550005783	carboxylate-amine ligase; Provisional; Region: PRK13515
926550005784	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
926550005785	carboxylate-amine ligase; Provisional; Region: PRK13515
926550005786	carboxylate-amine ligase, YbdK family; Region: gshA_cyan_rel; TIGR02050
926550005787	A circularly permuted ATPgrasp; Region: CP_ATPgrasp_1; cl17448
926550005788	Rhomboid family; Region: Rhomboid; pfam01694
926550005789	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926550005790	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550005791	Probable Catalytic site; other site
926550005792	metal-binding site
926550005793	methylthioribose-1-phosphate isomerase; Reviewed; Region: mtnA; PRK05720
926550005794	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182
926550005795	Possible lysine decarboxylase; Region: Lysine_decarbox; cl00695
926550005796	Ribokinase-like subgroup A.  Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_A; cd01942
926550005797	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550005798	substrate binding site [chemical binding]; other site
926550005799	ATP binding site [chemical binding]; other site
926550005800	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
926550005801	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550005802	Coenzyme A binding pocket [chemical binding]; other site
926550005803	S-adenosyl-L-homocysteine hydrolase; Provisional; Region: PRK05476
926550005804	S-Adenosylhomocysteine Hydrolase, NAD-binding and catalytic domains; Region: SAHH; cd00401
926550005805	homotetramer interface [polypeptide binding]; other site
926550005806	ligand binding site [chemical binding]; other site
926550005807	catalytic site [active]
926550005808	NAD binding site [chemical binding]; other site
926550005809	S-adenosylmethionine synthetase; Validated; Region: PRK05250
926550005810	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
926550005811	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
926550005812	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
926550005813	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926550005814	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550005815	molybdopterin cofactor binding site; other site
926550005816	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550005817	The MopB_CT_3 CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. This CD is of the...; Region: MopB_CT_3; cd02786
926550005818	putative molybdopterin cofactor binding site; other site
926550005819	FeoA domain; Region: FeoA; cl00838
926550005820	Elongation factor Tu GTP binding domain; Region: GTP_EFTU; pfam00009
926550005821	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
926550005822	G1 box; other site
926550005823	GTP/Mg2+ binding site [chemical binding]; other site
926550005824	Switch I region; other site
926550005825	G2 box; other site
926550005826	G3 box; other site
926550005827	Switch II region; other site
926550005828	G4 box; other site
926550005829	G5 box; other site
926550005830	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
926550005831	Nucleoside recognition; Region: Gate; pfam07670
926550005832	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
926550005833	FeoC like transcriptional regulator; Region: FeoC; pfam09012
926550005834	CHAT domain; Region: CHAT; pfam12770
926550005835	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550005836	Coenzyme A binding pocket [chemical binding]; other site
926550005837	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550005838	active site residue [active]
926550005839	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, isobutyryl-CoA mutase (ICM)-like subfamily; contains archaeal and bacterial proteins similar to the large subunit of Streptomyces cinnamonensis coenzyme B12-dependent ICM. ICM...; Region: MM_CoA_mutase_ICM_like; cd03680
926550005840	recombination protein RecR; Reviewed; Region: recR; PRK00076
926550005841	RecR protein; Region: RecR; pfam02132
926550005842	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
926550005843	putative active site [active]
926550005844	putative metal-binding site [ion binding]; other site
926550005845	tetramer interface [polypeptide binding]; other site
926550005846	hypothetical protein; Validated; Region: PRK00153
926550005847	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
926550005848	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550005849	Walker A motif; other site
926550005850	ATP binding site [chemical binding]; other site
926550005851	Walker B motif; other site
926550005852	DNA polymerase III subunit delta'; Validated; Region: PRK08485
926550005853	arginine finger; other site
926550005854	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
926550005855	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550005856	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550005857	DNA binding site [nucleotide binding]
926550005858	domain linker motif; other site
926550005859	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550005860	dimerization interface [polypeptide binding]; other site
926550005861	ligand binding site [chemical binding]; other site
926550005862	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550005863	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550005864	active site
926550005865	catalytic tetrad [active]
926550005866	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550005867	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550005868	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550005869	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005870	dimer interface [polypeptide binding]; other site
926550005871	conserved gate region; other site
926550005872	putative PBP binding loops; other site
926550005873	ABC-ATPase subunit interface; other site
926550005874	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550005875	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005876	conserved gate region; other site
926550005877	ABC-ATPase subunit interface; other site
926550005878	Alpha-L-fucosidase; Region: Alpha_L_fucos; cl12119
926550005879	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
926550005880	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
926550005881	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
926550005882	Alpha-L-fucosidase; Region: Alpha_L_fucos; smart00812
926550005883	Alpha-L-fucosidase [Carbohydrate transport and metabolism]; Region: COG3669
926550005884	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
926550005885	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
926550005886	ABC-ATPase subunit  interface; other site
926550005887	dimer interface [polypeptide binding]; other site
926550005888	putative PBP binding regions; other site
926550005889	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
926550005890	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
926550005891	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
926550005892	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
926550005893	CoA-ligase; Region: Ligase_CoA; pfam00549
926550005894	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
926550005895	CoA binding domain; Region: CoA_binding; pfam02629
926550005896	CoA-ligase; Region: Ligase_CoA; pfam00549
926550005897	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
926550005898	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
926550005899	Interdomain contacts; other site
926550005900	Cytokine receptor motif; other site
926550005901	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550005902	CHAT domain; Region: CHAT; cl17868
926550005903	AAA ATPase domain; Region: AAA_16; pfam13191
926550005904	AAA domain; Region: AAA_22; pfam13401
926550005905	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926550005906	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550005907	binding surface
926550005908	TPR motif; other site
926550005909	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550005910	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550005911	binding surface
926550005912	TPR motif; other site
926550005913	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550005914	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; TIGR03606
926550005915	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550005916	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550005917	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550005918	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005919	dimer interface [polypeptide binding]; other site
926550005920	conserved gate region; other site
926550005921	ABC-ATPase subunit interface; other site
926550005922	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550005923	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005924	dimer interface [polypeptide binding]; other site
926550005925	conserved gate region; other site
926550005926	putative PBP binding loops; other site
926550005927	ABC-ATPase subunit interface; other site
926550005928	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550005929	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550005930	DNA binding site [nucleotide binding]
926550005931	domain linker motif; other site
926550005932	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550005933	dimerization interface [polypeptide binding]; other site
926550005934	ligand binding site [chemical binding]; other site
926550005935	DMSO reductase family type II enzyme, iron-sulfur subunit; Region: DMSO_red_II_bet; TIGR03478
926550005936	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
926550005937	Heme-binding domain of bacterial ethylbenzene dehydrogenase; Region: DOMON_EBDH; cd09623
926550005938	heme binding site [chemical binding]; other site
926550005939	beta subunit binding site [polypeptide binding]; other site
926550005940	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
926550005941	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550005942	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550005943	Uncharacterized conserved protein [Function unknown]; Region: COG3189
926550005944	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
926550005945	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
926550005946	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
926550005947	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
926550005948	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
926550005949	siderophore binding site; other site
926550005950	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
926550005951	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
926550005952	siderophore binding site; other site
926550005953	iron-enterobactin transporter periplasmic binding protein; Provisional; Region: PRK10957
926550005954	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
926550005955	siderophore binding site; other site
926550005956	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
926550005957	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
926550005958	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
926550005959	ABC-ATPase subunit  interface; other site
926550005960	dimer interface [polypeptide binding]; other site
926550005961	putative PBP binding regions; other site
926550005962	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
926550005963	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
926550005964	ABC-ATPase subunit  interface; other site
926550005965	dimer interface [polypeptide binding]; other site
926550005966	putative PBP binding regions; other site
926550005967	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
926550005968	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
926550005969	Walker A/P-loop; other site
926550005970	ATP binding site [chemical binding]; other site
926550005971	Q-loop/lid; other site
926550005972	ABC transporter signature motif; other site
926550005973	Walker B; other site
926550005974	D-loop; other site
926550005975	H-loop/switch region; other site
926550005976	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550005977	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550005978	DNA binding site [nucleotide binding]
926550005979	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550005980	dimerization interface [polypeptide binding]; other site
926550005981	ligand binding site [chemical binding]; other site
926550005982	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550005983	substrate binding site [chemical binding]; other site
926550005984	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550005985	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550005986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005987	dimer interface [polypeptide binding]; other site
926550005988	conserved gate region; other site
926550005989	putative PBP binding loops; other site
926550005990	ABC-ATPase subunit interface; other site
926550005991	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550005992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550005993	dimer interface [polypeptide binding]; other site
926550005994	conserved gate region; other site
926550005995	putative PBP binding loops; other site
926550005996	ABC-ATPase subunit interface; other site
926550005997	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550005998	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550005999	Walker A/P-loop; other site
926550006000	ATP binding site [chemical binding]; other site
926550006001	Q-loop/lid; other site
926550006002	ABC transporter signature motif; other site
926550006003	Walker B; other site
926550006004	D-loop; other site
926550006005	H-loop/switch region; other site
926550006006	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550006007	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
926550006008	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550006009	Walker A/P-loop; other site
926550006010	ATP binding site [chemical binding]; other site
926550006011	Q-loop/lid; other site
926550006012	ABC transporter signature motif; other site
926550006013	Walker B; other site
926550006014	D-loop; other site
926550006015	H-loop/switch region; other site
926550006016	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
926550006017	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926550006018	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550006019	Walker A/P-loop; other site
926550006020	ATP binding site [chemical binding]; other site
926550006021	Q-loop/lid; other site
926550006022	ABC transporter signature motif; other site
926550006023	Walker B; other site
926550006024	D-loop; other site
926550006025	H-loop/switch region; other site
926550006026	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550006027	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550006028	Walker A/P-loop; other site
926550006029	ATP binding site [chemical binding]; other site
926550006030	Q-loop/lid; other site
926550006031	ABC transporter signature motif; other site
926550006032	Walker B; other site
926550006033	D-loop; other site
926550006034	H-loop/switch region; other site
926550006035	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550006036	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550006037	TM-ABC transporter signature motif; other site
926550006038	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550006039	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550006040	TM-ABC transporter signature motif; other site
926550006041	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
926550006042	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
926550006043	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
926550006044	active site residue [active]
926550006045	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
926550006046	active site residue [active]
926550006047	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550006048	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550006049	NMT1/THI5 like; Region: NMT1; pfam09084
926550006050	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
926550006051	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926550006052	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926550006053	Walker A/P-loop; other site
926550006054	ATP binding site [chemical binding]; other site
926550006055	Q-loop/lid; other site
926550006056	ABC transporter signature motif; other site
926550006057	Walker B; other site
926550006058	D-loop; other site
926550006059	H-loop/switch region; other site
926550006060	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926550006061	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006062	dimer interface [polypeptide binding]; other site
926550006063	conserved gate region; other site
926550006064	putative PBP binding loops; other site
926550006065	ABC-ATPase subunit interface; other site
926550006066	Putative regulatory protein; Region: CxxC_CXXC_SSSS; smart00834
926550006067	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
926550006068	Zn binding site [ion binding]; other site
926550006069	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550006070	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
926550006071	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
926550006072	Zn binding site [ion binding]; other site
926550006073	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
926550006074	Asp-box motif; other site
926550006075	BNR repeat-like domain; Region: BNR_2; pfam13088
926550006076	glutamate carboxypeptidase; Reviewed; Region: PRK06133
926550006077	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
926550006078	metal binding site [ion binding]; metal-binding site
926550006079	dimer interface [polypeptide binding]; other site
926550006080	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
926550006081	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550006082	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
926550006083	active site
926550006084	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
926550006085	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926550006086	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
926550006087	iron-sulfur cluster biosynthesis transcriptional regulator SufR; Region: SufR_cyano; TIGR02702
926550006088	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550006089	putative DNA binding site [nucleotide binding]; other site
926550006090	putative Zn2+ binding site [ion binding]; other site
926550006091	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
926550006092	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550006093	FeS/SAM binding site; other site
926550006094	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
926550006095	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
926550006096	Uncharacterized conserved protein (DUF2203); Region: DUF2203; pfam09969
926550006097	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
926550006098	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
926550006099	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
926550006100	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
926550006101	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
926550006102	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550006103	FeS/SAM binding site; other site
926550006104	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550006105	Radical SAM superfamily; Region: Radical_SAM; pfam04055
926550006106	FeS/SAM binding site; other site
926550006107	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
926550006108	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
926550006109	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550006110	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550006111	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
926550006112	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
926550006113	classical (c) SDRs; Region: SDR_c; cd05233
926550006114	NAD(P) binding site [chemical binding]; other site
926550006115	active site
926550006116	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
926550006117	classical (c) SDRs; Region: SDR_c; cd05233
926550006118	NAD(P) binding site [chemical binding]; other site
926550006119	active site
926550006120	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
926550006121	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
926550006122	[2Fe-2S] cluster binding site [ion binding]; other site
926550006123	C-terminal catalytic domain of plant choline monooxygenase (CMO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_CMO-like; cd08883
926550006124	putative alpha subunit interface [polypeptide binding]; other site
926550006125	putative active site [active]
926550006126	putative substrate binding site [chemical binding]; other site
926550006127	Fe binding site [ion binding]; other site
926550006128	Protein of unknown function (DUF2961); Region: DUF2961; pfam11175
926550006129	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
926550006130	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550006131	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926550006132	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550006133	substrate binding pocket [chemical binding]; other site
926550006134	membrane-bound complex binding site; other site
926550006135	hinge residues; other site
926550006136	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006137	dimer interface [polypeptide binding]; other site
926550006138	conserved gate region; other site
926550006139	putative PBP binding loops; other site
926550006140	ABC-ATPase subunit interface; other site
926550006141	bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Validated; Region: PRK05537
926550006142	ATP-sulfurylase; Region: ATPS; cd00517
926550006143	active site
926550006144	HXXH motif; other site
926550006145	flexible loop; other site
926550006146	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
926550006147	ligand-binding site [chemical binding]; other site
926550006148	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
926550006149	active site
926550006150	SAM binding site [chemical binding]; other site
926550006151	homodimer interface [polypeptide binding]; other site
926550006152	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
926550006153	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
926550006154	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
926550006155	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
926550006156	Active Sites [active]
926550006157	sulfite reductase subunit beta; Provisional; Region: PRK13504
926550006158	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926550006159	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
926550006160	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
926550006161	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
926550006162	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550006163	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550006164	homodimer interface [polypeptide binding]; other site
926550006165	catalytic residue [active]
926550006166	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
926550006167	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550006168	RNA binding surface [nucleotide binding]; other site
926550006169	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
926550006170	active site
926550006171	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
926550006172	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
926550006173	Competence protein; Region: Competence; pfam03772
926550006174	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
926550006175	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
926550006176	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926550006177	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926550006178	protein binding site [polypeptide binding]; other site
926550006179	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550006180	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550006181	Lamin Tail Domain; Region: LTD; pfam00932
926550006182	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
926550006183	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
926550006184	Dimer interface [polypeptide binding]; other site
926550006185	anticodon binding site; other site
926550006186	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
926550006187	homodimer interface [polypeptide binding]; other site
926550006188	motif 1; other site
926550006189	motif 2; other site
926550006190	active site
926550006191	motif 3; other site
926550006192	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
926550006193	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
926550006194	Mg++ binding site [ion binding]; other site
926550006195	putative catalytic motif [active]
926550006196	substrate binding site [chemical binding]; other site
926550006197	Protein of unknown function (DUF4013); Region: DUF4013; pfam13197
926550006198	META domain; Region: META; pfam03724
926550006199	META domain; Region: META; pfam03724
926550006200	peptidase T; Region: peptidase-T; TIGR01882
926550006201	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
926550006202	metal binding site [ion binding]; metal-binding site
926550006203	dimer interface [polypeptide binding]; other site
926550006204	Immune inhibitor A peptidase M6; Region: Peptidase_M6; cl11525
926550006205	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in a group of uncharacterized proteins from bacteria and archaea; Region: NTP-PPase_u4; cd11541
926550006206	putative metal binding site [ion binding]; other site
926550006207	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
926550006208	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550006209	Transcriptional regulator [Transcription]; Region: IclR; COG1414
926550006210	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
926550006211	Bacterial transcriptional regulator; Region: IclR; pfam01614
926550006212	4-aminobutyrate aminotransferase; Provisional; Region: PRK05769
926550006213	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550006214	inhibitor-cofactor binding pocket; inhibition site
926550006215	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550006216	catalytic residue [active]
926550006217	polyphosphate:nucleotide phosphotransferase, PPK2 family; Region: PPK2_rel_1; TIGR03709
926550006218	Chlorite dismutase; Region: Chlor_dismutase; cl01280
926550006219	Ferrochelatase; Region: Ferrochelatase; pfam00762
926550006220	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
926550006221	C-terminal domain interface [polypeptide binding]; other site
926550006222	active site
926550006223	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
926550006224	active site
926550006225	N-terminal domain interface [polypeptide binding]; other site
926550006226	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
926550006227	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
926550006228	tRNA; other site
926550006229	putative tRNA binding site [nucleotide binding]; other site
926550006230	putative NADP binding site [chemical binding]; other site
926550006231	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
926550006232	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
926550006233	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
926550006234	domain interfaces; other site
926550006235	active site
926550006236	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
926550006237	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
926550006238	active site
926550006239	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
926550006240	dimer interface [polypeptide binding]; other site
926550006241	active site
926550006242	Schiff base residues; other site
926550006243	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
926550006244	substrate binding site [chemical binding]; other site
926550006245	active site
926550006246	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
926550006247	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550006248	inhibitor-cofactor binding pocket; inhibition site
926550006249	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550006250	catalytic residue [active]
926550006251	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
926550006252	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550006253	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
926550006254	putative ADP-ribose binding site [chemical binding]; other site
926550006255	putative active site [active]
926550006256	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
926550006257	homodimer interface [polypeptide binding]; other site
926550006258	maltodextrin glucosidase; Provisional; Region: PRK10785
926550006259	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
926550006260	active site
926550006261	homodimer interface [polypeptide binding]; other site
926550006262	catalytic site [active]
926550006263	The family 20 carbohydrate-binding module (CBM20), also known as the starch-binding domain, is found in a large number of starch degrading enzymes including alpha-amylase, beta-amylase, glucoamylase, and CGTase (cyclodextrin glucanotransferase). CBM20 is...; Region: CBM20; cl15347
926550006264	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550006265	acetyl-CoA synthetase; Provisional; Region: PRK04319
926550006266	Domain of unknown function (DUF3448); Region: DUF3448; pfam11930
926550006267	Uncharacterized subfamily of Acetyl-CoA synthetase like family (ACS); Region: MACS_like_4; cd05969
926550006268	active site
926550006269	acyl-activating enzyme (AAE) consensus motif; other site
926550006270	putative CoA binding site [chemical binding]; other site
926550006271	AMP binding site [chemical binding]; other site
926550006272	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926550006273	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550006274	tetramer interface [polypeptide binding]; other site
926550006275	TPP-binding site [chemical binding]; other site
926550006276	heterodimer interface [polypeptide binding]; other site
926550006277	phosphorylation loop region [posttranslational modification]
926550006278	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550006279	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926550006280	alpha subunit interface [polypeptide binding]; other site
926550006281	TPP binding site [chemical binding]; other site
926550006282	heterodimer interface [polypeptide binding]; other site
926550006283	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550006284	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
926550006285	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550006286	E3 interaction surface; other site
926550006287	lipoyl attachment site [posttranslational modification]; other site
926550006288	e3 binding domain; Region: E3_binding; pfam02817
926550006289	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550006290	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
926550006291	4Fe-4S dicluster domain; Region: Fer4_18; pfam13746
926550006292	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
926550006293	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
926550006294	FAD binding pocket [chemical binding]; other site
926550006295	FAD binding motif [chemical binding]; other site
926550006296	phosphate binding motif [ion binding]; other site
926550006297	beta-alpha-beta structure motif; other site
926550006298	NAD binding pocket [chemical binding]; other site
926550006299	Iron coordination center [ion binding]; other site
926550006300	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
926550006301	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
926550006302	Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing...; Region: H2MP; cd00518
926550006303	nickel binding site [ion binding]; other site
926550006304	putative selenium metabolism hydrolase; Region: selenium_YgeY; TIGR03526
926550006305	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
926550006306	putative metal binding site [ion binding]; other site
926550006307	putative dimer interface [polypeptide binding]; other site
926550006308	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
926550006309	carbamate kinase; Reviewed; Region: PRK12686
926550006310	putative substrate binding site [chemical binding]; other site
926550006311	nucleotide binding site [chemical binding]; other site
926550006312	nucleotide binding site [chemical binding]; other site
926550006313	homodimer interface [polypeptide binding]; other site
926550006314	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550006315	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550006316	gamma-aminobutyraldehyde dehydrogenase; Provisional; Region: PRK13473
926550006317	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
926550006318	tetrameric interface [polypeptide binding]; other site
926550006319	NAD binding site [chemical binding]; other site
926550006320	catalytic residues [active]
926550006321	substrate binding site [chemical binding]; other site
926550006322	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926550006323	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550006324	Walker A/P-loop; other site
926550006325	ATP binding site [chemical binding]; other site
926550006326	Q-loop/lid; other site
926550006327	ABC transporter signature motif; other site
926550006328	Walker B; other site
926550006329	D-loop; other site
926550006330	H-loop/switch region; other site
926550006331	TOBE domain; Region: TOBE_2; pfam08402
926550006332	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550006333	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006334	conserved gate region; other site
926550006335	putative PBP binding loops; other site
926550006336	ABC-ATPase subunit interface; other site
926550006337	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550006338	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006339	dimer interface [polypeptide binding]; other site
926550006340	conserved gate region; other site
926550006341	putative PBP binding loops; other site
926550006342	ABC-ATPase subunit interface; other site
926550006343	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
926550006344	Clp amino terminal domain; Region: Clp_N; pfam02861
926550006345	Clp amino terminal domain; Region: Clp_N; pfam02861
926550006346	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550006347	Walker A motif; other site
926550006348	ATP binding site [chemical binding]; other site
926550006349	Walker B motif; other site
926550006350	arginine finger; other site
926550006351	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550006352	Walker A motif; other site
926550006353	ATP binding site [chemical binding]; other site
926550006354	Walker B motif; other site
926550006355	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
926550006356	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926550006357	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926550006358	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
926550006359	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926550006360	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550006361	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550006362	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550006363	Walker A/P-loop; other site
926550006364	ATP binding site [chemical binding]; other site
926550006365	Q-loop/lid; other site
926550006366	ABC transporter signature motif; other site
926550006367	Walker B; other site
926550006368	D-loop; other site
926550006369	H-loop/switch region; other site
926550006370	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550006371	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
926550006372	FtsX-like permease family; Region: FtsX; pfam02687
926550006373	Transcriptional regulator [Transcription]; Region: LysR; COG0583
926550006374	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926550006375	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
926550006376	putative dimerization interface [polypeptide binding]; other site
926550006377	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550006378	active site residue [active]
926550006379	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
926550006380	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926550006381	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550006382	active site residue [active]
926550006383	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926550006384	Zinc ribbon domain; Region: CxxC_CxxC_SSSS; pfam09723
926550006385	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550006386	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550006387	Predicted ATPase [General function prediction only]; Region: COG3903
926550006388	Walker A motif; other site
926550006389	ATP binding site [chemical binding]; other site
926550006390	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550006391	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550006392	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550006393	binding surface
926550006394	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550006395	TPR motif; other site
926550006396	Putative flagellar system-associated repeat; Region: SWM_repeat; pfam13753
926550006397	adhesin; Provisional; Region: PRK09752
926550006398	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
926550006399	metal ion-dependent adhesion site (MIDAS); other site
926550006400	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926550006401	DNA-binding site [nucleotide binding]; DNA binding site
926550006402	RNA-binding motif; other site
926550006403	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
926550006404	Carbohydrate kinase and ribulose-phosphate 3-epimerase fusion proteins-like; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_CarbK-RPE_like; cd07783
926550006405	N- and C-terminal domain interface [polypeptide binding]; other site
926550006406	active site
926550006407	MgATP binding site [chemical binding]; other site
926550006408	catalytic site [active]
926550006409	metal binding site [ion binding]; metal-binding site
926550006410	putative carbohydrate binding site [chemical binding]; other site
926550006411	putative homodimer interface [polypeptide binding]; other site
926550006412	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
926550006413	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
926550006414	substrate binding site [chemical binding]; other site
926550006415	hexamer interface [polypeptide binding]; other site
926550006416	metal binding site [ion binding]; metal-binding site
926550006417	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550006418	ABC-2 type transporter; Region: ABC2_membrane; cl17235
926550006419	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926550006420	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550006421	RNA binding surface [nucleotide binding]; other site
926550006422	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006423	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006424	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006425	ParB-like nuclease domain; Region: ParBc; cl02129
926550006426	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
926550006427	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
926550006428	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
926550006429	HflX GTPase family; Region: HflX; cd01878
926550006430	G1 box; other site
926550006431	GTP/Mg2+ binding site [chemical binding]; other site
926550006432	Switch I region; other site
926550006433	G2 box; other site
926550006434	G3 box; other site
926550006435	Switch II region; other site
926550006436	G4 box; other site
926550006437	G5 box; other site
926550006438	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
926550006439	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
926550006440	Mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues; Region: MR_like; cd03316
926550006441	active site pocket [active]
926550006442	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550006443	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550006444	TM-ABC transporter signature motif; other site
926550006445	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550006446	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550006447	Walker A/P-loop; other site
926550006448	ATP binding site [chemical binding]; other site
926550006449	Q-loop/lid; other site
926550006450	ABC transporter signature motif; other site
926550006451	Walker B; other site
926550006452	D-loop; other site
926550006453	H-loop/switch region; other site
926550006454	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550006455	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550006456	excinuclease ABC subunit B; Provisional; Region: PRK05298
926550006457	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
926550006458	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550006459	ATP-binding site [chemical binding]; other site
926550006460	ATP binding site [chemical binding]; other site
926550006461	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550006462	nucleotide binding region [chemical binding]; other site
926550006463	ATP-binding site [chemical binding]; other site
926550006464	Ultra-violet resistance protein B; Region: UvrB; pfam12344
926550006465	DNA gyrase subunit A; Validated; Region: PRK05560
926550006466	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
926550006467	CAP-like domain; other site
926550006468	active site
926550006469	primary dimer interface [polypeptide binding]; other site
926550006470	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006471	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006472	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006473	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550006474	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550006475	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
926550006476	putative substrate translocation pore; other site
926550006477	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
926550006478	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
926550006479	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926550006480	glutamine synthetase, type I; Region: GlnA; TIGR00653
926550006481	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
926550006482	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926550006483	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
926550006484	FAD binding domain; Region: FAD_binding_4; pfam01565
926550006485	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
926550006486	Virulence factor; Region: Virulence_fact; pfam13769
926550006487	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
926550006488	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
926550006489	Methylene-tetrahydrofolate reductase C terminal; Region: MTHFR_C; pfam12225
926550006490	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
926550006491	FAD binding site [chemical binding]; other site
926550006492	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
926550006493	methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; Validated; Region: PRK07535
926550006494	substrate binding pocket [chemical binding]; other site
926550006495	dimer interface [polypeptide binding]; other site
926550006496	inhibitor binding site; inhibition site
926550006497	Protein of unknown function (DUF1638); Region: DUF1638; pfam07796
926550006498	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550006499	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550006500	DNA binding site [nucleotide binding]
926550006501	domain linker motif; other site
926550006502	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550006503	dimerization interface [polypeptide binding]; other site
926550006504	ligand binding site [chemical binding]; other site
926550006505	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550006506	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550006507	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006508	dimer interface [polypeptide binding]; other site
926550006509	conserved gate region; other site
926550006510	putative PBP binding loops; other site
926550006511	ABC-ATPase subunit interface; other site
926550006512	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550006513	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006514	dimer interface [polypeptide binding]; other site
926550006515	conserved gate region; other site
926550006516	putative PBP binding loops; other site
926550006517	ABC-ATPase subunit interface; other site
926550006518	Glycosyl hydrolase families: GH43, GH62, GH32, GH68; Region: GH43_62_32_68; cl14647
926550006519	active site
926550006520	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
926550006521	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
926550006522	active site
926550006523	Family 41 Carbohydrate-Binding Module from pullulanase-like enzymes; Region: CBM41_pullulanase; cd10315
926550006524	carbohydrate binding site [chemical binding]; other site
926550006525	alpha-1,6-glucosidases, pullulanase-type; Region: pullul_strch; TIGR02103
926550006526	Early set domain associated with the catalytic domain of pullulanase (also called dextrinase and alpha-dextrin endo-1,6-alpha glucosidase); Region: E_set_Pullulanase; cd02860
926550006527	Alpha amylase catalytic domain found in Pullulanase (also called dextrinase; alpha-dextrin endo-1,6-alpha glucosidase), limit dextrinase, and related proteins; Region: AmyAc_Pullulanase_LD-like; cd11341
926550006528	Ca binding site [ion binding]; other site
926550006529	active site
926550006530	catalytic site [active]
926550006531	Domain of unknown function (DUF3372); Region: DUF3372; pfam11852
926550006532	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
926550006533	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550006534	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
926550006535	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550006536	Cupin domain; Region: Cupin_2; pfam07883
926550006537	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550006538	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
926550006539	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550006540	Phytanoyl-CoA dioxygenase (PhyH); Region: PhyH; pfam05721
926550006541	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
926550006542	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
926550006543	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
926550006544	Family description; Region: VCBS; pfam13517
926550006545	Family description; Region: VCBS; pfam13517
926550006546	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
926550006547	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550006548	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006549	dimer interface [polypeptide binding]; other site
926550006550	conserved gate region; other site
926550006551	putative PBP binding loops; other site
926550006552	ABC-ATPase subunit interface; other site
926550006553	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550006554	dimer interface [polypeptide binding]; other site
926550006555	conserved gate region; other site
926550006556	putative PBP binding loops; other site
926550006557	ABC-ATPase subunit interface; other site
926550006558	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550006559	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550006560	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
926550006561	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550006562	TPR motif; other site
926550006563	binding surface
926550006564	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550006565	binding surface
926550006566	TPR motif; other site
926550006567	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550006568	TPR motif; other site
926550006569	TPR repeat; Region: TPR_11; pfam13414
926550006570	binding surface
926550006571	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
926550006572	binding surface
926550006573	TPR motif; other site
926550006574	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
926550006575	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
926550006576	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550006577	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550006578	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
926550006579	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C); Region: NT5C; cl17836
926550006580	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550006581	motif II; other site
926550006582	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550006583	Coenzyme A binding pocket [chemical binding]; other site
926550006584	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
926550006585	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
926550006586	homodimer interface [polypeptide binding]; other site
926550006587	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550006588	catalytic residue [active]
926550006589	ribonuclease III; Reviewed; Region: rnc; PRK00102
926550006590	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
926550006591	dimerization interface [polypeptide binding]; other site
926550006592	active site
926550006593	metal binding site [ion binding]; metal-binding site
926550006594	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
926550006595	dsRNA binding site [nucleotide binding]; other site
926550006596	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
926550006597	AAA domain; Region: AAA_23; pfam13476
926550006598	Walker A/P-loop; other site
926550006599	ATP binding site [chemical binding]; other site
926550006600	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
926550006601	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
926550006602	Q-loop/lid; other site
926550006603	ABC transporter signature motif; other site
926550006604	Walker B; other site
926550006605	D-loop; other site
926550006606	H-loop/switch region; other site
926550006607	Cytochrome c; Region: Cytochrom_C; pfam00034
926550006608	Cytochrome c; Region: Cytochrom_C; pfam00034
926550006609	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
926550006610	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cl00859
926550006611	heme bH binding site [chemical binding]; other site
926550006612	intrachain domain interface; other site
926550006613	heme bL binding site [chemical binding]; other site
926550006614	interchain domain interface [polypeptide binding]; other site
926550006615	Qo binding site; other site
926550006616	Cytochrome b(C-terminus)/b6/petD:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: cytochrome_b_C; cl00193
926550006617	intrachain domain interface; other site
926550006618	Qo binding site; other site
926550006619	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
926550006620	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
926550006621	iron-sulfur cluster [ion binding]; other site
926550006622	[2Fe-2S] cluster binding site [ion binding]; other site
926550006623	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
926550006624	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
926550006625	dimer interface [polypeptide binding]; other site
926550006626	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550006627	catalytic residue [active]
926550006628	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
926550006629	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926550006630	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550006631	ATP binding site [chemical binding]; other site
926550006632	putative Mg++ binding site [ion binding]; other site
926550006633	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550006634	nucleotide binding region [chemical binding]; other site
926550006635	ATP-binding site [chemical binding]; other site
926550006636	HRDC domain; Region: HRDC; pfam00570
926550006637	HRDC domain; Region: HRDC; pfam00570
926550006638	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
926550006639	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
926550006640	dimer interface [polypeptide binding]; other site
926550006641	active site
926550006642	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
926550006643	Ferritin-like domain; Region: Ferritin; pfam00210
926550006644	dinuclear metal binding motif [ion binding]; other site
926550006645	PIN domain; Region: PIN_3; cl17397
926550006646	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; cl09153
926550006647	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550006648	Protein of unknown function DUF45; Region: DUF45; cl00636
926550006649	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
926550006650	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
926550006651	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550006652	ATP binding site [chemical binding]; other site
926550006653	putative Mg++ binding site [ion binding]; other site
926550006654	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cl03075
926550006655	Transposase IS200 like; Region: Y1_Tnp; cl00848
926550006656	Uncharacterized conserved protein [Function unknown]; Region: COG1479
926550006657	Protein of unknown function DUF262; Region: DUF262; pfam03235
926550006658	Protein of unknown function DUF262; Region: DUF262; pfam03235
926550006659	Uncharacterized conserved protein [Function unknown]; Region: COG3472
926550006660	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
926550006661	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
926550006662	Protein of unknown function DUF86; Region: DUF86; cl01031
926550006663	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550006664	active site
926550006665	NTP binding site [chemical binding]; other site
926550006666	metal binding triad [ion binding]; metal-binding site
926550006667	antibiotic binding site [chemical binding]; other site
926550006668	Divergent AAA domain; Region: AAA_4; pfam04326
926550006669	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
926550006670	HsdM N-terminal domain; Region: HsdM_N; pfam12161
926550006671	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
926550006672	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550006673	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550006674	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550006675	nucleotide binding site [chemical binding]; other site
926550006676	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
926550006677	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550006678	active site
926550006679	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550006680	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550006681	NAD(P) binding site [chemical binding]; other site
926550006682	active site
926550006683	epoxyqueuosine reductase; Region: TIGR00276
926550006684	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
926550006685	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550006686	putative substrate translocation pore; other site
926550006687	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550006688	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550006689	Predicted transcriptional regulator [Transcription]; Region: COG2345
926550006690	putative Zn2+ binding site [ion binding]; other site
926550006691	putative DNA binding site [nucleotide binding]; other site
926550006692	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
926550006693	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
926550006694	Walker A/P-loop; other site
926550006695	ATP binding site [chemical binding]; other site
926550006696	Q-loop/lid; other site
926550006697	ABC transporter signature motif; other site
926550006698	Walker B; other site
926550006699	D-loop; other site
926550006700	H-loop/switch region; other site
926550006701	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
926550006702	FeS assembly protein SufB; Region: sufB; TIGR01980
926550006703	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
926550006704	FeS assembly protein SufD; Region: sufD; TIGR01981
926550006705	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
926550006706	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
926550006707	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550006708	catalytic residue [active]
926550006709	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
926550006710	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
926550006711	trimerization site [polypeptide binding]; other site
926550006712	active site
926550006713	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
926550006714	[2Fe-2S] cluster binding site [ion binding]; other site
926550006715	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
926550006716	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
926550006717	Cytochrome P450; Region: p450; cl12078
926550006718	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
926550006719	phytoene desaturase; Region: crtI_fam; TIGR02734
926550006720	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550006721	hopene-associated glycosyltransferase HpnB; Region: HpnB; TIGR03469
926550006722	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
926550006723	active site
926550006724	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
926550006725	Protein of unknown function (DUF422); Region: DUF422; cl00991
926550006726	NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691
926550006727	AIR carboxylase; Region: AIRC; smart01001
926550006728	ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606
926550006729	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_I; cd01990
926550006730	Ligand Binding Site [chemical binding]; other site
926550006731	Protein of unknown function DUF111; Region: DUF111; pfam01969
926550006732	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
926550006733	Leucyl aminopeptidase (aminopeptidase T) [Amino acid transport and metabolism]; Region: AmpS; COG2309
926550006734	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550006735	Coenzyme A binding pocket [chemical binding]; other site
926550006736	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550006737	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550006738	Walker A/P-loop; other site
926550006739	ATP binding site [chemical binding]; other site
926550006740	Q-loop/lid; other site
926550006741	ABC transporter signature motif; other site
926550006742	Walker B; other site
926550006743	D-loop; other site
926550006744	H-loop/switch region; other site
926550006745	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
926550006746	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
926550006747	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
926550006748	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
926550006749	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550006750	Glutaredoxin-like domain protein; Region: GlrX_arch; TIGR02187
926550006751	Thioredoxin (TRX)-Glutaredoxin (GRX)-like family; composed of archaeal and bacterial proteins that show similarity to both TRX and GRX, including the C-terminal TRX-fold subdomain of Pyrococcus furiosus protein disulfide oxidoreductase (PfPDO). All...; Region: TRX_GRX_like; cd02973
926550006752	catalytic residues [active]
926550006753	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
926550006754	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550006755	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550006756	DNA binding residues [nucleotide binding]
926550006757	Putative zinc-finger; Region: zf-HC2; pfam13490
926550006758	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550006759	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550006760	NAD(P) binding site [chemical binding]; other site
926550006761	active site
926550006762	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
926550006763	Histone deacetylase class IV also known as histone deacetylase 11; Region: HDAC_classIV; cd09993
926550006764	putative active site [active]
926550006765	Zn binding site [ion binding]; other site
926550006766	thymidine kinase; Provisional; Region: PRK04296
926550006767	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
926550006768	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
926550006769	50S ribosomal protein L21/unknown domain fusion protein; Provisional; Region: PRK12278
926550006770	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
926550006771	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550006772	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550006773	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550006774	putative substrate translocation pore; other site
926550006775	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550006776	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
926550006777	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550006778	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550006779	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550006780	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550006781	Walker A/P-loop; other site
926550006782	ATP binding site [chemical binding]; other site
926550006783	Q-loop/lid; other site
926550006784	ABC transporter signature motif; other site
926550006785	Walker B; other site
926550006786	D-loop; other site
926550006787	H-loop/switch region; other site
926550006788	Cation transport protein; Region: TrkH; cl17365
926550006789	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
926550006790	PAS domain S-box; Region: sensory_box; TIGR00229
926550006791	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
926550006792	putative active site [active]
926550006793	heme pocket [chemical binding]; other site
926550006794	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550006795	ATP binding site [chemical binding]; other site
926550006796	Mg2+ binding site [ion binding]; other site
926550006797	G-X-G motif; other site
926550006798	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550006799	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550006800	active site
926550006801	phosphorylation site [posttranslational modification]
926550006802	intermolecular recognition site; other site
926550006803	dimerization interface [polypeptide binding]; other site
926550006804	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
926550006805	homodimer interface [polypeptide binding]; other site
926550006806	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
926550006807	active site pocket [active]
926550006808	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
926550006809	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926550006810	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
926550006811	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
926550006812	dimer interface [polypeptide binding]; other site
926550006813	TrkA-C domain; Region: TrkA_C; pfam02080
926550006814	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
926550006815	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
926550006816	Ligand binding site; other site
926550006817	Putative Catalytic site; other site
926550006818	DXD motif; other site
926550006819	Anion-transporting ATPase; Region: ArsA_ATPase; pfam02374
926550006820	ArsA ATPase functionas as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces...; Region: ArsA; cd02035
926550006821	DTAP/Switch II; other site
926550006822	Switch I; other site
926550006823	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
926550006824	This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins.  sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa; Region: ACD_sHsps_p23-like; cd00298
926550006825	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550006826	S-adenosylmethionine binding site [chemical binding]; other site
926550006827	tRNA pseudouridine synthase D (TruD); Region: TruD; pfam01142
926550006828	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
926550006829	Permutation of conserved domain; other site
926550006830	active site
926550006831	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
926550006832	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
926550006833	M20 Peptidases, Poly(aspartic acid) hydrolase-like proteins; Region: M20_PAAh_like; cd03896
926550006834	Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases [Amino acid transport and metabolism]; Region: ArgE; COG0624
926550006835	putative metal binding site [ion binding]; other site
926550006836	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
926550006837	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
926550006838	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
926550006839	active site
926550006840	dimer interface [polypeptide binding]; other site
926550006841	motif 1; other site
926550006842	motif 2; other site
926550006843	motif 3; other site
926550006844	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
926550006845	anticodon binding site; other site
926550006846	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
926550006847	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
926550006848	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
926550006849	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
926550006850	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
926550006851	23S rRNA binding site [nucleotide binding]; other site
926550006852	L21 binding site [polypeptide binding]; other site
926550006853	L13 binding site [polypeptide binding]; other site
926550006854	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
926550006855	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
926550006856	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
926550006857	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
926550006858	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
926550006859	NAD(P) binding site [chemical binding]; other site
926550006860	catalytic residues [active]
926550006861	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
926550006862	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
926550006863	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
926550006864	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
926550006865	ABC-2 type transporter; Region: ABC2_membrane; cl17235
926550006866	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550006867	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550006868	Walker A/P-loop; other site
926550006869	ATP binding site [chemical binding]; other site
926550006870	Q-loop/lid; other site
926550006871	ABC transporter signature motif; other site
926550006872	Walker B; other site
926550006873	D-loop; other site
926550006874	H-loop/switch region; other site
926550006875	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
926550006876	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550006877	active site
926550006878	motif I; other site
926550006879	motif II; other site
926550006880	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550006881	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926550006882	Binding-protein-dependent transport system inner membrane component; Region: BPD_transp_1; pfam00528
926550006883	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
926550006884	Catalytic domain of Protein Kinases; Region: PKc; cd00180
926550006885	active site
926550006886	ATP binding site [chemical binding]; other site
926550006887	substrate binding site [chemical binding]; other site
926550006888	activation loop (A-loop); other site
926550006889	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
926550006890	Cytochrome P450; Region: p450; cl12078
926550006891	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550006892	PAS domain; Region: PAS_9; pfam13426
926550006893	putative active site [active]
926550006894	heme pocket [chemical binding]; other site
926550006895	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550006896	GAF domain; Region: GAF_3; pfam13492
926550006897	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550006898	Histidine kinase; Region: HisKA_3; pfam07730
926550006899	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550006900	ATP binding site [chemical binding]; other site
926550006901	Mg2+ binding site [ion binding]; other site
926550006902	G-X-G motif; other site
926550006903	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550006904	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550006905	active site
926550006906	phosphorylation site [posttranslational modification]
926550006907	intermolecular recognition site; other site
926550006908	dimerization interface [polypeptide binding]; other site
926550006909	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550006910	DNA binding residues [nucleotide binding]
926550006911	dimerization interface [polypeptide binding]; other site
926550006912	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
926550006913	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
926550006914	active site
926550006915	substrate-binding site [chemical binding]; other site
926550006916	metal-binding site [ion binding]
926550006917	ATP binding site [chemical binding]; other site
926550006918	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550006919	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
926550006920	active site
926550006921	phosphorylation site [posttranslational modification]
926550006922	intermolecular recognition site; other site
926550006923	alkyl hydroperoxide reductase subunit F; Region: AhpF; TIGR03140
926550006924	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550006925	Mechanosensitive ion channel; Region: MS_channel; pfam00924
926550006926	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550006927	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550006928	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550006929	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
926550006930	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
926550006931	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550006932	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
926550006933	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
926550006934	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926550006935	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
926550006936	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550006937	Walker A/P-loop; other site
926550006938	ATP binding site [chemical binding]; other site
926550006939	Q-loop/lid; other site
926550006940	ABC transporter signature motif; other site
926550006941	Walker B; other site
926550006942	D-loop; other site
926550006943	H-loop/switch region; other site
926550006944	ATP-binding cassette domain of MutS homologs; Region: ABC_MutS_homologs; cd03243
926550006945	Walker A/P-loop; other site
926550006946	ATP binding site [chemical binding]; other site
926550006947	Q-loop/lid; other site
926550006948	ABC transporter signature motif; other site
926550006949	Walker B; other site
926550006950	D-loop; other site
926550006951	H-loop/switch region; other site
926550006952	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550006953	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550006954	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
926550006955	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
926550006956	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550006957	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550006958	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
926550006959	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926550006960	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926550006961	metal-binding site [ion binding]
926550006962	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550006963	Soluble P-type ATPase [General function prediction only]; Region: COG4087
926550006964	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550006965	dimerization interface [polypeptide binding]; other site
926550006966	putative DNA binding site [nucleotide binding]; other site
926550006967	putative Zn2+ binding site [ion binding]; other site
926550006968	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550006969	Walker A/P-loop; other site
926550006970	ATP binding site [chemical binding]; other site
926550006971	ABC transporter; Region: ABC_tran; pfam00005
926550006972	Q-loop/lid; other site
926550006973	ABC transporter signature motif; other site
926550006974	Walker B; other site
926550006975	D-loop; other site
926550006976	H-loop/switch region; other site
926550006977	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550006978	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550006979	integron integrase; Region: integrase_gron; TIGR02249
926550006980	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
926550006981	Int/Topo IB signature motif; other site
926550006982	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
926550006983	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
926550006984	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
926550006985	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550006986	S-adenosylmethionine binding site [chemical binding]; other site
926550006987	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
926550006988	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550006989	putative active site [active]
926550006990	putative metal binding site [ion binding]; other site
926550006991	Coenzyme F390 synthetase [Coenzyme metabolism]; Region: PaaK; COG1541
926550006992	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550006993	acyl-activating enzyme (AAE) consensus motif; other site
926550006994	active site
926550006995	AMP binding site [chemical binding]; other site
926550006996	CoA binding site [chemical binding]; other site
926550006997	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
926550006998	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
926550006999	TPP-binding site [chemical binding]; other site
926550007000	dimer interface [polypeptide binding]; other site
926550007001	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
926550007002	PYR/PP interface [polypeptide binding]; other site
926550007003	dimer interface [polypeptide binding]; other site
926550007004	TPP binding site [chemical binding]; other site
926550007005	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550007006	DNA polymerase III, delta subunit; Region: holA; TIGR01128
926550007007	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
926550007008	recombination protein F; Reviewed; Region: recF; PRK00064
926550007009	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550007010	Walker A/P-loop; other site
926550007011	ATP binding site [chemical binding]; other site
926550007012	Q-loop/lid; other site
926550007013	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550007014	ABC transporter signature motif; other site
926550007015	Walker B; other site
926550007016	D-loop; other site
926550007017	H-loop/switch region; other site
926550007018	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550007019	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
926550007020	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926550007021	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
926550007022	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
926550007023	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
926550007024	Thermotoga maritima CorA-like family; Region: TmCorA-like; cd12822
926550007025	oligomer interface [polypeptide binding]; other site
926550007026	metal binding site [ion binding]; metal-binding site
926550007027	metal binding site [ion binding]; metal-binding site
926550007028	putative Cl binding site [ion binding]; other site
926550007029	aspartate ring; other site
926550007030	basic sphincter; other site
926550007031	hydrophobic gate; other site
926550007032	periplasmic entrance; other site
926550007033	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
926550007034	active site
926550007035	Ap6A binding site [chemical binding]; other site
926550007036	nudix motif; other site
926550007037	metal binding site [ion binding]; metal-binding site
926550007038	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
926550007039	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
926550007040	dimer interface [polypeptide binding]; other site
926550007041	active site
926550007042	lycopene cyclase family protein; Region: carotene-cycl; TIGR01790
926550007043	lycopene cyclase; Region: lycopene_cycl; TIGR01789
926550007044	Peptidase_C39 like family; Region: Peptidase_C39_2; pfam13529
926550007045	putative active site [active]
926550007046	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550007047	Bacterial membrane protein YfhO; Region: YfhO; pfam09586
926550007048	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550007049	active site
926550007050	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926550007051	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550007052	inhibitor-cofactor binding pocket; inhibition site
926550007053	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550007054	catalytic residue [active]
926550007055	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550007056	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550007057	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550007058	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550007059	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550007060	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
926550007061	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550007062	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
926550007063	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550007064	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926550007065	substrate binding site [chemical binding]; other site
926550007066	ATP binding site [chemical binding]; other site
926550007067	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926550007068	Patatin-like phospholipase domain containing protein 6, protein 7, and fungal NTE1; Region: Pat_PNPLA6_PNPLA7_NTE1_like; cd07205
926550007069	nucleophile elbow; other site
926550007070	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550007071	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
926550007072	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
926550007073	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550007074	NAD(P) binding site [chemical binding]; other site
926550007075	Enoylreductase; Region: PKS_ER; smart00829
926550007076	methylmalonyl-CoA decarboxylase alpha subunit; Region: mmdA; TIGR01117
926550007077	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
926550007078	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
926550007079	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
926550007080	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
926550007081	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550007082	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
926550007083	putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK05641
926550007084	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
926550007085	carboxyltransferase (CT) interaction site; other site
926550007086	biotinylation site [posttranslational modification]; other site
926550007087	Membrane protein of unknown function; Region: DUF360; pfam04020
926550007088	PIN domain of ribonucleases (toxins), VapC and FitB, of prokaryotic toxin/antitoxin operons, Pyrococcus horikoshii protein PH0500, and other similar bacterial and archaeal homologs; Region: PIN_VapC-FitB; cd09881
926550007089	oligomeric interface; other site
926550007090	homodimer interface [polypeptide binding]; other site
926550007091	putative active site [active]
926550007092	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926550007093	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926550007094	Cu(I) binding site [ion binding]; other site
926550007095	2'-5' RNA ligase [Translation, ribosomal structure and biogenesis]; Region: LigT; COG1514
926550007096	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
926550007097	prephenate dehydrogenase; Validated; Region: PRK08507
926550007098	Prephenate dehydrogenase; Region: PDH; pfam02153
926550007099	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
926550007100	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
926550007101	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
926550007102	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
926550007103	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
926550007104	Prephenate dehydratase; Region: PDT; pfam00800
926550007105	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
926550007106	putative L-Phe binding site [chemical binding]; other site
926550007107	Chorismate mutase (AroH) is one of at least five chorismate-utilizing enzymes present in microorganisms that catalyze the rearrangement of chorismate to prephenic acid, the first committed step in the biosynthesis of aromatic amino acids. In prokaryotes; Region: AroH; cd02185
926550007108	homotrimer interaction site [polypeptide binding]; other site
926550007109	active site
926550007110	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550007111	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926550007112	substrate binding site [chemical binding]; other site
926550007113	ATP binding site [chemical binding]; other site
926550007114	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
926550007115	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
926550007116	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550007117	ATP binding site [chemical binding]; other site
926550007118	putative Mg++ binding site [ion binding]; other site
926550007119	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550007120	nucleotide binding region [chemical binding]; other site
926550007121	ATP-binding site [chemical binding]; other site
926550007122	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
926550007123	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
926550007124	putative active site [active]
926550007125	catalytic residue [active]
926550007126	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
926550007127	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
926550007128	Thioredoxin; Region: Thioredoxin_4; pfam13462
926550007129	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
926550007130	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
926550007131	putative active site [active]
926550007132	putative metal binding site [ion binding]; other site
926550007133	Bacterial capsule synthesis protein PGA_cap; Region: PGA_cap; smart00854
926550007134	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
926550007135	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550007136	putative NAD(P) binding site [chemical binding]; other site
926550007137	catalytic Zn binding site [ion binding]; other site
926550007138	Chain length determinant protein; Region: Wzz; pfam02706
926550007139	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
926550007140	SnoaL-like domain; Region: SnoaL_2; pfam12680
926550007141	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550007142	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550007143	nucleotide binding site [chemical binding]; other site
926550007144	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
926550007145	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
926550007146	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cl17460
926550007147	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
926550007148	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007149	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007150	dimer interface [polypeptide binding]; other site
926550007151	conserved gate region; other site
926550007152	putative PBP binding loops; other site
926550007153	ABC-ATPase subunit interface; other site
926550007154	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550007155	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007156	ABC-ATPase subunit interface; other site
926550007157	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550007158	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007159	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550007160	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550007161	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550007162	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
926550007163	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
926550007164	phosphate binding site [ion binding]; other site
926550007165	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550007166	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550007167	NAD(P) binding site [chemical binding]; other site
926550007168	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926550007169	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
926550007170	DNA binding residues [nucleotide binding]
926550007171	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926550007172	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
926550007173	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
926550007174	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550007175	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
926550007176	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550007177	DNA binding residues [nucleotide binding]
926550007178	DNA primase, catalytic core; Region: dnaG; TIGR01391
926550007179	CHC2 zinc finger; Region: zf-CHC2; cl17510
926550007180	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
926550007181	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
926550007182	active site
926550007183	metal binding site [ion binding]; metal-binding site
926550007184	interdomain interaction site; other site
926550007185	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
926550007186	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550007187	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550007188	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550007189	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cl10029
926550007190	N-acetylmuramic acid-6-phosphate etherase; Reviewed; Region: murQ; PRK05441
926550007191	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
926550007192	putative active site [active]
926550007193	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
926550007194	putative active site pocket [active]
926550007195	4-fold oligomerization interface [polypeptide binding]; other site
926550007196	metal binding residues [ion binding]; metal-binding site
926550007197	3-fold/trimer interface [polypeptide binding]; other site
926550007198	histidinol-phosphate aminotransferase; Provisional; Region: PLN03026
926550007199	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550007200	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550007201	homodimer interface [polypeptide binding]; other site
926550007202	catalytic residue [active]
926550007203	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
926550007204	histidinol dehydrogenase; Region: hisD; TIGR00069
926550007205	NAD binding site [chemical binding]; other site
926550007206	dimerization interface [polypeptide binding]; other site
926550007207	product binding site; other site
926550007208	substrate binding site [chemical binding]; other site
926550007209	zinc binding site [ion binding]; other site
926550007210	catalytic residues [active]
926550007211	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
926550007212	putative active site [active]
926550007213	nucleotide binding site [chemical binding]; other site
926550007214	nudix motif; other site
926550007215	putative metal binding site [ion binding]; other site
926550007216	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
926550007217	Recombination protein O N terminal; Region: RecO_N; pfam11967
926550007218	Recombination protein O C terminal; Region: RecO_C; pfam02565
926550007219	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
926550007220	LexA repressor; Validated; Region: PRK00215
926550007221	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
926550007222	Catalytic site [active]
926550007223	acyl carrier protein; Provisional; Region: acpP; PRK00982
926550007224	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550007225	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550007226	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550007227	Bacterial SH3 domain homologues; Region: SH3b; smart00287
926550007228	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
926550007229	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
926550007230	ligand binding site [chemical binding]; other site
926550007231	NAD binding site [chemical binding]; other site
926550007232	dimerization interface [polypeptide binding]; other site
926550007233	catalytic site [active]
926550007234	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
926550007235	putative L-serine binding site [chemical binding]; other site
926550007236	arginyl-tRNA synthetase; Reviewed; Region: argS; PRK01611
926550007237	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
926550007238	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
926550007239	active site
926550007240	HIGH motif; other site
926550007241	KMSK motif region; other site
926550007242	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
926550007243	tRNA binding surface [nucleotide binding]; other site
926550007244	anticodon binding site; other site
926550007245	DNA polymerase I; Provisional; Region: PRK05755
926550007246	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
926550007247	active site
926550007248	metal binding site 1 [ion binding]; metal-binding site
926550007249	putative 5' ssDNA interaction site; other site
926550007250	metal binding site 3; metal-binding site
926550007251	metal binding site 2 [ion binding]; metal-binding site
926550007252	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
926550007253	putative DNA binding site [nucleotide binding]; other site
926550007254	putative metal binding site [ion binding]; other site
926550007255	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
926550007256	active site
926550007257	catalytic site [active]
926550007258	substrate binding site [chemical binding]; other site
926550007259	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
926550007260	active site
926550007261	DNA binding site [nucleotide binding]
926550007262	catalytic site [active]
926550007263	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550007264	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550007265	active site
926550007266	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
926550007267	putative binding surface; other site
926550007268	active site
926550007269	Elongation factor G (EF-G) family; Region: EF-G_bact; cd04170
926550007270	elongation factor G; Reviewed; Region: PRK12740
926550007271	G1 box; other site
926550007272	putative GEF interaction site [polypeptide binding]; other site
926550007273	GTP/Mg2+ binding site [chemical binding]; other site
926550007274	Switch I region; other site
926550007275	G2 box; other site
926550007276	G3 box; other site
926550007277	Switch II region; other site
926550007278	G4 box; other site
926550007279	G5 box; other site
926550007280	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
926550007281	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
926550007282	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
926550007283	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007284	dimer interface [polypeptide binding]; other site
926550007285	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550007286	conserved gate region; other site
926550007287	putative PBP binding loops; other site
926550007288	ABC-ATPase subunit interface; other site
926550007289	Predicted metal-binding protein [General function prediction only]; Region: COG3019
926550007290	Phenylalanine ammonia-lyase (PAL) and histidine ammonia-lyase (HAL); Region: PAL-HAL; cd00332
926550007291	active sites [active]
926550007292	tetramer interface [polypeptide binding]; other site
926550007293	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
926550007294	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926550007295	P-loop; other site
926550007296	Magnesium ion binding site [ion binding]; other site
926550007297	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
926550007298	Magnesium ion binding site [ion binding]; other site
926550007299	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
926550007300	Divergent AAA domain; Region: AAA_4; pfam04326
926550007301	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
926550007302	chromate transporter, chromate ion transporter (CHR) family; Region: 2A51; TIGR00937
926550007303	Chromate transport protein ChrA [Inorganic ion transport and metabolism]; Region: ChrA; COG2059
926550007304	Chromate transporter; Region: Chromate_transp; pfam02417
926550007305	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550007306	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550007307	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
926550007308	Walker A/P-loop; other site
926550007309	ATP binding site [chemical binding]; other site
926550007310	Q-loop/lid; other site
926550007311	ABC transporter signature motif; other site
926550007312	Walker B; other site
926550007313	D-loop; other site
926550007314	H-loop/switch region; other site
926550007315	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550007316	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550007317	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
926550007318	Walker A/P-loop; other site
926550007319	ATP binding site [chemical binding]; other site
926550007320	Q-loop/lid; other site
926550007321	ABC transporter signature motif; other site
926550007322	Walker B; other site
926550007323	D-loop; other site
926550007324	H-loop/switch region; other site
926550007325	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926550007326	MarR family; Region: MarR; pfam01047
926550007327	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550007328	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550007329	ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]; Region: COG1051
926550007330	nudix motif; other site
926550007331	Uncharacterized conserved protein [General function prediction only]; Region: COG4111
926550007332	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
926550007333	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
926550007334	NAD binding site [chemical binding]; other site
926550007335	homotetramer interface [polypeptide binding]; other site
926550007336	homodimer interface [polypeptide binding]; other site
926550007337	substrate binding site [chemical binding]; other site
926550007338	active site
926550007339	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
926550007340	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
926550007341	active site
926550007342	HIGH motif; other site
926550007343	dimer interface [polypeptide binding]; other site
926550007344	KMSKS motif; other site
926550007345	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550007346	RNA binding surface [nucleotide binding]; other site
926550007347	L-fucose isomerase; Provisional; Region: fucI; PRK10991
926550007348	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
926550007349	hexamer (dimer of trimers) interface [polypeptide binding]; other site
926550007350	trimer interface [polypeptide binding]; other site
926550007351	substrate binding site [chemical binding]; other site
926550007352	Mn binding site [ion binding]; other site
926550007353	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550007354	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007355	Carbohydrate Binding Module 6 (CBM6); appended to several carbohydrate binding enzymes, including several glycoside hydrolase (GH) family 26 mannanase domains; Region: CBM6_mannanase-like; cd04086
926550007356	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550007357	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007358	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007359	dimer interface [polypeptide binding]; other site
926550007360	conserved gate region; other site
926550007361	putative PBP binding loops; other site
926550007362	ABC-ATPase subunit interface; other site
926550007363	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007364	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007365	dimer interface [polypeptide binding]; other site
926550007366	conserved gate region; other site
926550007367	ABC-ATPase subunit interface; other site
926550007368	Gluconolactonase [Carbohydrate transport and metabolism]; Region: COG3386
926550007369	Tetratricopeptide repeat; Region: TPR_16; pfam13432
926550007370	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550007371	TPR motif; other site
926550007372	binding surface
926550007373	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
926550007374	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550007375	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007376	dimer interface [polypeptide binding]; other site
926550007377	conserved gate region; other site
926550007378	ABC-ATPase subunit interface; other site
926550007379	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007380	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007381	dimer interface [polypeptide binding]; other site
926550007382	conserved gate region; other site
926550007383	putative PBP binding loops; other site
926550007384	ABC-ATPase subunit interface; other site
926550007385	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
926550007386	Putative glucoamylase; Region: Glycoamylase; pfam10091
926550007387	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550007388	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550007389	DNA binding site [nucleotide binding]
926550007390	domain linker motif; other site
926550007391	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550007392	dimerization interface [polypeptide binding]; other site
926550007393	ligand binding site [chemical binding]; other site
926550007394	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
926550007395	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550007396	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550007397	ABC transporter; Region: ABC_tran_2; pfam12848
926550007398	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550007399	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550007400	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550007401	oxidoreductase; Validated; Region: PRK05717
926550007402	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550007403	NAD(P) binding site [chemical binding]; other site
926550007404	active site
926550007405	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
926550007406	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550007407	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550007408	catalytic residue [active]
926550007409	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550007410	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926550007411	Metal-binding active site; metal-binding site
926550007412	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
926550007413	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
926550007414	transcription termination factor Rho; Provisional; Region: PRK12608
926550007415	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
926550007416	Walker A motif; other site
926550007417	ATP binding site [chemical binding]; other site
926550007418	Walker B motif; other site
926550007419	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
926550007420	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
926550007421	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
926550007422	metal binding site [ion binding]; metal-binding site
926550007423	dimer interface [polypeptide binding]; other site
926550007424	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; smart00790
926550007425	Aldehyde:ferredoxin oxidoreductase [Energy production and conversion]; Region: COG2414
926550007426	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
926550007427	helix_turn_helix, Lux Regulon; Region: HTH_LUXR; smart00421
926550007428	dimerization interface [polypeptide binding]; other site
926550007429	DNA binding residues [nucleotide binding]
926550007430	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
926550007431	dimerization interface [polypeptide binding]; other site
926550007432	putative ATP binding site [chemical binding]; other site
926550007433	ATP-grasp domain; Region: ATP-grasp_4; cl17255
926550007434	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4947
926550007435	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550007436	active site
926550007437	catalytic residues [active]
926550007438	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
926550007439	Sortase family; Region: Sortase; pfam04203
926550007440	active site
926550007441	catalytic site [active]
926550007442	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550007443	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550007444	active site
926550007445	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
926550007446	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926550007447	Bacterial SH3 domain; Region: SH3_3; cl17532
926550007448	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550007449	conserved repeat domain; Region: B_ant_repeat; TIGR01451
926550007450	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
926550007451	Protein of unknown function (DUF4012); Region: DUF4012; pfam13196
926550007452	NAD-dependent deacetylase; Provisional; Region: PRK00481
926550007453	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
926550007454	NAD+ binding site [chemical binding]; other site
926550007455	substrate binding site [chemical binding]; other site
926550007456	Zn binding site [ion binding]; other site
926550007457	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
926550007458	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926550007459	Walker A/P-loop; other site
926550007460	ATP binding site [chemical binding]; other site
926550007461	Q-loop/lid; other site
926550007462	ABC transporter signature motif; other site
926550007463	Walker B; other site
926550007464	D-loop; other site
926550007465	H-loop/switch region; other site
926550007466	TOBE domain; Region: TOBE_2; pfam08402
926550007467	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550007468	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007469	active site
926550007470	phosphorylation site [posttranslational modification]
926550007471	intermolecular recognition site; other site
926550007472	dimerization interface [polypeptide binding]; other site
926550007473	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550007474	DNA binding site [nucleotide binding]
926550007475	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
926550007476	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
926550007477	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550007478	catalytic residue [active]
926550007479	H(+) -translocating inorganic pyrophosphatase; Region: PLN02255; cl11452
926550007480	Inorganic H+ pyrophosphatase; Region: H_PPase; pfam03030
926550007481	site-specific tyrosine recombinase XerD-like protein; Reviewed; Region: xerD; PRK02436
926550007482	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
926550007483	1-cyclohexenylcarbonyl_coenzyme A_reductase (ChcA)_like, classical (c) SDRs; Region: ChcA_like_SDR_c; cd05359
926550007484	putative NAD(P) binding site [chemical binding]; other site
926550007485	active site
926550007486	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
926550007487	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550007488	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
926550007489	active site
926550007490	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
926550007491	Enoyl-CoA hydratase/isomerase family; Region: ECH; pfam00378
926550007492	substrate binding site [chemical binding]; other site
926550007493	oxyanion hole (OAH) forming residues; other site
926550007494	trimer interface [polypeptide binding]; other site
926550007495	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylic-acid synthase; Region: menD; TIGR00173
926550007496	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
926550007497	dimer interface [polypeptide binding]; other site
926550007498	tetramer interface [polypeptide binding]; other site
926550007499	PYR/PP interface [polypeptide binding]; other site
926550007500	TPP binding site [chemical binding]; other site
926550007501	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926550007502	TPP-binding site [chemical binding]; other site
926550007503	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
926550007504	Protein of unknown function (DUF461); Region: DUF461; pfam04314
926550007505	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
926550007506	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550007507	putative NAD(P) binding site [chemical binding]; other site
926550007508	catalytic Zn binding site [ion binding]; other site
926550007509	structural Zn binding site [ion binding]; other site
926550007510	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
926550007511	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
926550007512	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
926550007513	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
926550007514	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
926550007515	NMT1/THI5 like; Region: NMT1; pfam09084
926550007516	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
926550007517	ATP-dependent transcriptional regulator [Transcription]; Region: MalT; COG2909
926550007518	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550007519	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
926550007520	dimer interface [polypeptide binding]; other site
926550007521	substrate binding site [chemical binding]; other site
926550007522	ATP binding site [chemical binding]; other site
926550007523	Putative transcription activator [Transcription]; Region: TenA; COG0819
926550007524	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
926550007525	thiamine phosphate binding site [chemical binding]; other site
926550007526	active site
926550007527	pyrophosphate binding site [ion binding]; other site
926550007528	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
926550007529	thiamine phosphate binding site [chemical binding]; other site
926550007530	active site
926550007531	pyrophosphate binding site [ion binding]; other site
926550007532	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
926550007533	ThiS interaction site; other site
926550007534	putative active site [active]
926550007535	tetramer interface [polypeptide binding]; other site
926550007536	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
926550007537	thiS-thiF/thiG interaction site; other site
926550007538	glycine oxidase ThiO; Region: thiamin_ThiO; TIGR02352
926550007539	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926550007540	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211
926550007541	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550007542	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926550007543	substrate binding site [chemical binding]; other site
926550007544	ATP binding site [chemical binding]; other site
926550007545	alpha-galactosidase; Provisional; Region: PRK15076
926550007546	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
926550007547	NAD(P) binding site [chemical binding]; other site
926550007548	LDH/MDH dimer interface [polypeptide binding]; other site
926550007549	substrate binding site [chemical binding]; other site
926550007550	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007551	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007552	dimer interface [polypeptide binding]; other site
926550007553	conserved gate region; other site
926550007554	putative PBP binding loops; other site
926550007555	ABC-ATPase subunit interface; other site
926550007556	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550007557	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007558	dimer interface [polypeptide binding]; other site
926550007559	conserved gate region; other site
926550007560	putative PBP binding loops; other site
926550007561	ABC-ATPase subunit interface; other site
926550007562	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550007563	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007564	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
926550007565	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
926550007566	dimer interface [polypeptide binding]; other site
926550007567	active site
926550007568	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
926550007569	dimer interface [polypeptide binding]; other site
926550007570	active site
926550007571	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926550007572	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
926550007573	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926550007574	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
926550007575	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550007576	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
926550007577	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
926550007578	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550007579	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550007580	dimer interface [polypeptide binding]; other site
926550007581	phosphorylation site [posttranslational modification]
926550007582	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550007583	ATP binding site [chemical binding]; other site
926550007584	Mg2+ binding site [ion binding]; other site
926550007585	G-X-G motif; other site
926550007586	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
926550007587	active site
926550007588	phosphorylation site [posttranslational modification]
926550007589	intermolecular recognition site; other site
926550007590	dimerization interface [polypeptide binding]; other site
926550007591	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007592	Response regulator receiver domain; Region: Response_reg; pfam00072
926550007593	active site
926550007594	phosphorylation site [posttranslational modification]
926550007595	intermolecular recognition site; other site
926550007596	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550007597	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007598	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007599	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550007600	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007601	dimer interface [polypeptide binding]; other site
926550007602	putative PBP binding loops; other site
926550007603	ABC-ATPase subunit interface; other site
926550007604	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007605	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007606	dimer interface [polypeptide binding]; other site
926550007607	conserved gate region; other site
926550007608	putative PBP binding loops; other site
926550007609	ABC-ATPase subunit interface; other site
926550007610	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
926550007611	Putative glycosyl hydrolase of unknown function (DUF1680); Region: DUF1680; pfam07944
926550007612	Putative methyltransferase; Region: Methyltransf_4; cl17290
926550007613	Adenine specific DNA methylase Mod [DNA replication, recombination, and repair]; Region: COG2189
926550007614	DNA methylase; Region: N6_N4_Mtase; pfam01555
926550007615	Methyltransferase domain; Region: Methyltransf_23; pfam13489
926550007616	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550007617	S-adenosylmethionine binding site [chemical binding]; other site
926550007618	DPM1_like represents putative enzymes similar to eukaryotic DPM1; Region: DPM1_like; cd06442
926550007619	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
926550007620	Ligand binding site; other site
926550007621	Putative Catalytic site; other site
926550007622	DXD motif; other site
926550007623	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
926550007624	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550007625	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550007626	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550007627	Walker A/P-loop; other site
926550007628	ATP binding site [chemical binding]; other site
926550007629	Q-loop/lid; other site
926550007630	ABC transporter signature motif; other site
926550007631	Walker B; other site
926550007632	D-loop; other site
926550007633	H-loop/switch region; other site
926550007634	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550007635	1,4-dihydroxy-2-naphthoate octaprenyltransferase [Coenzyme metabolism]; Region: MenA; cl17224
926550007636	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
926550007637	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
926550007638	active site
926550007639	(T/H)XGH motif; other site
926550007640	Coproporphyrinogen III oxidase and related Fe-S oxidoreductases [Coenzyme metabolism]; Region: HemN; COG0635
926550007641	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550007642	FeS/SAM binding site; other site
926550007643	HemN C-terminal domain; Region: HemN_C; pfam06969
926550007644	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
926550007645	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
926550007646	phosphopeptide binding site; other site
926550007647	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550007648	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550007649	DNA binding site [nucleotide binding]
926550007650	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
926550007651	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
926550007652	active site
926550007653	ATP binding site [chemical binding]; other site
926550007654	substrate binding site [chemical binding]; other site
926550007655	activation loop (A-loop); other site
926550007656	Ammonium Transporter Family; Region: Ammonium_transp; cl03012
926550007657	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
926550007658	endonuclease IV; Provisional; Region: PRK01060
926550007659	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
926550007660	AP (apurinic/apyrimidinic) site pocket; other site
926550007661	DNA interaction; other site
926550007662	Metal-binding active site; metal-binding site
926550007663	Small Multidrug Resistance protein; Region: Multi_Drug_Res; cl00910
926550007664	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
926550007665	Protein of unknown function (DUF503); Region: DUF503; pfam04456
926550007666	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
926550007667	FAD binding domain; Region: FAD_binding_4; pfam01565
926550007668	Uncharacterized conserved protein [Function unknown]; Region: COG4850
926550007669	Uncharacterized conserved protein (DUF2183); Region: DUF2183; pfam09949
926550007670	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
926550007671	Interdomain contacts; other site
926550007672	Cytokine receptor motif; other site
926550007673	Uncharacterized conserved protein [Function unknown]; Region: COG3743
926550007674	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
926550007675	Domain of unknown function (DUF4332); Region: DUF4332; pfam14229
926550007676	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
926550007677	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550007678	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550007679	active site
926550007680	catalytic tetrad [active]
926550007681	hypothetical protein; Provisional; Region: PRK06148
926550007682	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
926550007683	active site
926550007684	ATP binding site [chemical binding]; other site
926550007685	substrate binding site [chemical binding]; other site
926550007686	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550007687	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550007688	inhibitor-cofactor binding pocket; inhibition site
926550007689	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550007690	catalytic residue [active]
926550007691	threonine synthase; Region: PLN02569
926550007692	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
926550007693	homodimer interface [polypeptide binding]; other site
926550007694	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550007695	catalytic residue [active]
926550007696	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
926550007697	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550007698	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
926550007699	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
926550007700	phosphopeptide binding site; other site
926550007701	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550007702	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550007703	DNA binding site [nucleotide binding]
926550007704	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
926550007705	Catalytic domain of Protein Kinases; Region: PKc; cd00180
926550007706	active site
926550007707	ATP binding site [chemical binding]; other site
926550007708	substrate binding site [chemical binding]; other site
926550007709	activation loop (A-loop); other site
926550007710	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550007711	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550007712	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550007713	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
926550007714	Catalytic domain of Protein Kinases; Region: PKc; cd00180
926550007715	active site
926550007716	ATP binding site [chemical binding]; other site
926550007717	substrate binding site [chemical binding]; other site
926550007718	activation loop (A-loop); other site
926550007719	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
926550007720	phosphate binding site [ion binding]; other site
926550007721	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
926550007722	Uncharacterized conserved protein [Function unknown]; Region: COG3743
926550007723	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
926550007724	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550007725	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550007726	DNA binding residues [nucleotide binding]
926550007727	magnesium chelatase ATPase subunit I; Region: BchI-ChlI; TIGR02030
926550007728	Mg-chelatase subunit ChlD [Coenzyme metabolism]; Region: ChlD; COG1240
926550007729	Magnesium chelatase: Mg-chelatase catalyses the insertion of Mg into protoporphyrin IX (Proto). In chlorophyll biosynthesis, insertion of Mg2+ into protoporphyrin IX is catalysed by magnesium chelatase in an ATP-dependent reaction. Magnesium chelatase is...; Region: vWA_Magnesium_chelatase; cd01451
926550007730	metal ion-dependent adhesion site (MIDAS); other site
926550007731	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926550007732	Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate,  or similar substrates; Region: Bacterial_IMPase_like_1; cd01641
926550007733	active site
926550007734	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
926550007735	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
926550007736	NADP binding site [chemical binding]; other site
926550007737	dimer interface [polypeptide binding]; other site
926550007738	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
926550007739	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
926550007740	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550007741	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550007742	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550007743	active site
926550007744	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550007745	catalytic tetrad [active]
926550007746	Uncharacterized conserved protein [Function unknown]; Region: COG1262
926550007747	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
926550007748	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
926550007749	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926550007750	active site
926550007751	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
926550007752	Lyase class I_like superfamily: contains the lyase class I family, histidine ammonia-lyase and phenylalanine ammonia-lyase, which catalyze similar beta-elimination reactions; Region: Lyase_I_like; cl00013
926550007753	tetramer interface [polypeptide binding]; other site
926550007754	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
926550007755	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550007756	S-adenosylmethionine binding site [chemical binding]; other site
926550007757	Periplasmic component of the Tol biopolymer transport system [Intracellular trafficking and secretion]; Region: TolB; COG0823
926550007758	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
926550007759	active site
926550007760	dimer interface [polypeptide binding]; other site
926550007761	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550007762	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007763	active site
926550007764	phosphorylation site [posttranslational modification]
926550007765	intermolecular recognition site; other site
926550007766	dimerization interface [polypeptide binding]; other site
926550007767	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550007768	DNA binding site [nucleotide binding]
926550007769	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550007770	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550007771	dimerization interface [polypeptide binding]; other site
926550007772	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550007773	dimer interface [polypeptide binding]; other site
926550007774	phosphorylation site [posttranslational modification]
926550007775	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550007776	ATP binding site [chemical binding]; other site
926550007777	Mg2+ binding site [ion binding]; other site
926550007778	G-X-G motif; other site
926550007779	Uncharacterized conserved protein [Function unknown]; Region: COG0432
926550007780	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
926550007781	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
926550007782	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550007783	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550007784	homodimer interface [polypeptide binding]; other site
926550007785	catalytic residue [active]
926550007786	cobyric acid synthase; Provisional; Region: PRK00784
926550007787	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
926550007788	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
926550007789	catalytic triad [active]
926550007790	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
926550007791	active site
926550007792	SAM binding site [chemical binding]; other site
926550007793	homodimer interface [polypeptide binding]; other site
926550007794	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
926550007795	homodimer interface [polypeptide binding]; other site
926550007796	active site
926550007797	SAM binding site [chemical binding]; other site
926550007798	Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) [Coenzyme metabolism]; Region: CysG; COG1648
926550007799	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
926550007800	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
926550007801	active site
926550007802	SAM binding site [chemical binding]; other site
926550007803	homodimer interface [polypeptide binding]; other site
926550007804	Cobalamin biosynthesis protein CbiG [Coenzyme metabolism]; Region: CbiG; COG2073
926550007805	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
926550007806	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
926550007807	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
926550007808	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
926550007809	active site
926550007810	SAM binding site [chemical binding]; other site
926550007811	homodimer interface [polypeptide binding]; other site
926550007812	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
926550007813	active site
926550007814	putative homodimer interface [polypeptide binding]; other site
926550007815	SAM binding site [chemical binding]; other site
926550007816	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
926550007817	precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Region: CbiT; TIGR02469
926550007818	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
926550007819	Precorrin-8X methylmutase; Region: CbiC; pfam02570
926550007820	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
926550007821	Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138
926550007822	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
926550007823	putative active site [active]
926550007824	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), C-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_C; cd03414
926550007825	putative active site [active]
926550007826	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
926550007827	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
926550007828	Walker A/P-loop; other site
926550007829	ATP binding site [chemical binding]; other site
926550007830	Q-loop/lid; other site
926550007831	ABC transporter signature motif; other site
926550007832	Walker B; other site
926550007833	D-loop; other site
926550007834	H-loop/switch region; other site
926550007835	cobalt ABC transporter, permease protein CbiQ; Region: CbiQ_TIGR; TIGR02454
926550007836	cobalt transport protein CbiN; Provisional; Region: PRK02898
926550007837	cobalt transport protein CbiM; Validated; Region: PRK08319
926550007838	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
926550007839	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
926550007840	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
926550007841	putative active site [active]
926550007842	homotetrameric interface [polypeptide binding]; other site
926550007843	metal binding site [ion binding]; metal-binding site
926550007844	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
926550007845	putative active site [active]
926550007846	NHL repeat; Region: NHL; pfam01436
926550007847	NHL repeat; Region: NHL; pfam01436
926550007848	NHL repeat; Region: NHL; pfam01436
926550007849	NHL repeat; Region: NHL; pfam01436
926550007850	NHL repeat; Region: NHL; pfam01436
926550007851	NHL repeat; Region: NHL; pfam01436
926550007852	FOG: PKD repeat [General function prediction only]; Region: COG3291
926550007853	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
926550007854	CHAP domain; Region: CHAP; cl17642
926550007855	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550007856	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550007857	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550007858	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550007859	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550007860	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926550007861	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550007862	ATP binding site [chemical binding]; other site
926550007863	putative Mg++ binding site [ion binding]; other site
926550007864	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550007865	nucleotide binding region [chemical binding]; other site
926550007866	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
926550007867	ATP-binding site [chemical binding]; other site
926550007868	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
926550007869	Protein of unknown function (DUF1156); Region: DUF1156; pfam06634
926550007870	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
926550007871	Transposase IS200 like; Region: Y1_Tnp; pfam01797
926550007872	Adenine-specific DNA methylase containing a Zn-ribbon [DNA replication, recombination, and repair]; Region: COG1743
926550007873	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1483
926550007874	Protein of unknown function (DUF499); Region: DUF499; pfam04465
926550007875	Uncharacterized protein conserved in bacteria (DUF2255); Region: DUF2255; cl01788
926550007876	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
926550007877	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550007878	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550007879	active site
926550007880	catalytic tetrad [active]
926550007881	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
926550007882	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
926550007883	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550007884	Intradiol dioxygenase supgroup. Intradiol dioxygenases catalyze the critical ring-cleavage step in the conversion of catecholate derivatives to citric acid cycle intermediates. They break the catechol C1-C2 bond and utilize Fe3+, as opposed to  the...; Region: intradiol_dioxygenase_like; cd03457
926550007885	putative active site [active]
926550007886	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
926550007887	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
926550007888	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
926550007889	NAD(P) binding site [chemical binding]; other site
926550007890	shikimate binding site; other site
926550007891	aldose 1-epimerase superfamily; Region: Aldose_epim; cl14648
926550007892	active site
926550007893	catalytic residues [active]
926550007894	Formate--tetrahydrofolate ligase; Region: PLN02759
926550007895	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
926550007896	Potassium binding sites [ion binding]; other site
926550007897	Cesium cation binding sites [ion binding]; other site
926550007898	RibD C-terminal domain; Region: RibD_C; cl17279
926550007899	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
926550007900	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550007901	tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Translation, ribosomal structure and biogenesis]; Region: GCD14; COG2519
926550007902	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550007903	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550007904	Uncharacterized protein family (UPF0182); Region: UPF0182; pfam03699
926550007905	Uncharacterized conserved protein [Function unknown]; Region: COG1615
926550007906	serine endoprotease; Provisional; Region: PRK10898
926550007907	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926550007908	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926550007909	protein binding site [polypeptide binding]; other site
926550007910	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
926550007911	GTP-binding protein YchF; Reviewed; Region: PRK09601
926550007912	YchF GTPase; Region: YchF; cd01900
926550007913	G1 box; other site
926550007914	GTP/Mg2+ binding site [chemical binding]; other site
926550007915	Switch I region; other site
926550007916	G2 box; other site
926550007917	Switch II region; other site
926550007918	G3 box; other site
926550007919	G4 box; other site
926550007920	G5 box; other site
926550007921	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
926550007922	ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) [Nucleotide transport and metabolism]; Region: APA2; COG4360
926550007923	ATP adenylyltransferase; Region: ATP_transf; pfam09830
926550007924	Response regulator receiver domain; Region: Response_reg; pfam00072
926550007925	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007926	active site
926550007927	phosphorylation site [posttranslational modification]
926550007928	intermolecular recognition site; other site
926550007929	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550007930	dimerization interface [polypeptide binding]; other site
926550007931	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550007932	dimer interface [polypeptide binding]; other site
926550007933	phosphorylation site [posttranslational modification]
926550007934	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550007935	ATP binding site [chemical binding]; other site
926550007936	Mg2+ binding site [ion binding]; other site
926550007937	G-X-G motif; other site
926550007938	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926550007939	Peptidase C26; Region: Peptidase_C26; pfam07722
926550007940	catalytic triad [active]
926550007941	Protein related to penicillin acylase [General function prediction only]; Region: COG2366
926550007942	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
926550007943	Penicillin G acylase (PGA) belongs to a family of beta-lactam acylases that includes cephalosporin acylase (CA) and aculeacin A acylase. PGA and CA are crucial for the production of backbone chemicals like 6-aminopenicillanic acid and...; Region: Ntn_PGA_like; cd03747
926550007944	active site
926550007945	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550007946	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550007947	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
926550007948	TrkA-C domain; Region: TrkA_C; pfam02080
926550007949	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
926550007950	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
926550007951	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
926550007952	dimerization interface [polypeptide binding]; other site
926550007953	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
926550007954	ATP binding site [chemical binding]; other site
926550007955	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
926550007956	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
926550007957	HupF/HypC family; Region: HupF_HypC; pfam01455
926550007958	EamA-like transporter family; Region: EamA; pfam00892
926550007959	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
926550007960	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
926550007961	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550007962	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550007963	dimerization interface [polypeptide binding]; other site
926550007964	ligand binding site [chemical binding]; other site
926550007965	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550007966	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550007967	dimer interface [polypeptide binding]; other site
926550007968	phosphorylation site [posttranslational modification]
926550007969	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550007970	ATP binding site [chemical binding]; other site
926550007971	Mg2+ binding site [ion binding]; other site
926550007972	G-X-G motif; other site
926550007973	Response regulator receiver domain; Region: Response_reg; pfam00072
926550007974	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007975	active site
926550007976	phosphorylation site [posttranslational modification]
926550007977	intermolecular recognition site; other site
926550007978	dimerization interface [polypeptide binding]; other site
926550007979	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550007980	active site
926550007981	phosphorylation site [posttranslational modification]
926550007982	intermolecular recognition site; other site
926550007983	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
926550007984	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
926550007985	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550007986	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550007987	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007988	putative PBP binding loops; other site
926550007989	dimer interface [polypeptide binding]; other site
926550007990	ABC-ATPase subunit interface; other site
926550007991	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550007992	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550007993	dimer interface [polypeptide binding]; other site
926550007994	conserved gate region; other site
926550007995	putative PBP binding loops; other site
926550007996	ABC-ATPase subunit interface; other site
926550007997	Beta-glucanase/Beta-glucan synthetase [Carbohydrate transport and metabolism]; Region: SKN1; COG2273
926550007998	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
926550007999	active site
926550008000	catalytic residues [active]
926550008001	Carbohydrate binding domain (family 11); Region: CBM_11; pfam03425
926550008002	Carbohydrate binding domain (family 11); Region: CBM_11; pfam03425
926550008003	Calx-beta domain; Region: Calx-beta; pfam03160
926550008004	Carbohydrate binding domain (family 11); Region: CBM_11; pfam03425
926550008005	Calx-beta domain; Region: Calx-beta; cl02522
926550008006	Laminarinase, member of the glycosyl hydrolase family 16; Region: GH16_laminarinase_like; cd08023
926550008007	active site
926550008008	catalytic residues [active]
926550008009	Carbohydrate binding domain (family 11); Region: CBM_11; pfam03425
926550008010	K+ transporter [Inorganic ion transport and metabolism]; Region: Kup; COG3158
926550008011	potassium uptake protein; Region: kup; TIGR00794
926550008012	Transcriptional regulators [Transcription]; Region: FadR; COG2186
926550008013	FCD domain; Region: FCD; pfam07729
926550008014	2-oxoacid:acceptor oxidoreductase, alpha subunit; Region: OAFO_sf; TIGR03710
926550008015	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
926550008016	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
926550008017	dimer interface [polypeptide binding]; other site
926550008018	PYR/PP interface [polypeptide binding]; other site
926550008019	TPP binding site [chemical binding]; other site
926550008020	substrate binding site [chemical binding]; other site
926550008021	2-oxoglutarate ferredoxin oxidoreductase subunit beta; Validated; Region: PRK05778
926550008022	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
926550008023	TPP-binding site [chemical binding]; other site
926550008024	Pyruvate ferredoxin oxidoreductase beta subunit C terminal; Region: PFO_beta_C; pfam12367
926550008025	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
926550008026	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
926550008027	putative acyl-acceptor binding pocket; other site
926550008028	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
926550008029	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
926550008030	putative acyl-acceptor binding pocket; other site
926550008031	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
926550008032	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
926550008033	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
926550008034	Bacitracin resistance protein BacA; Region: BacA; pfam02673
926550008035	PBP superfamily domain; Region: PBP_like_2; cl17296
926550008036	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926550008037	Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase) and related proteins; Region: AmyAc_OligoGlu_like; cd11331
926550008038	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
926550008039	active site
926550008040	catalytic site [active]
926550008041	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
926550008042	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550008043	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550008044	active site
926550008045	acetyl-CoA acetyltransferase; Validated; Region: PRK08242
926550008046	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926550008047	dimer interface [polypeptide binding]; other site
926550008048	active site
926550008049	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926550008050	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
926550008051	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926550008052	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
926550008053	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550008054	active site
926550008055	motif I; other site
926550008056	motif II; other site
926550008057	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550008058	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550008059	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550008060	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008061	dimer interface [polypeptide binding]; other site
926550008062	conserved gate region; other site
926550008063	putative PBP binding loops; other site
926550008064	ABC-ATPase subunit interface; other site
926550008065	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550008066	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008067	dimer interface [polypeptide binding]; other site
926550008068	conserved gate region; other site
926550008069	putative PBP binding loops; other site
926550008070	ABC-ATPase subunit interface; other site
926550008071	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926550008072	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926550008073	Walker A/P-loop; other site
926550008074	ATP binding site [chemical binding]; other site
926550008075	Q-loop/lid; other site
926550008076	ABC transporter signature motif; other site
926550008077	Walker B; other site
926550008078	D-loop; other site
926550008079	H-loop/switch region; other site
926550008080	TOBE domain; Region: TOBE_2; pfam08402
926550008081	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926550008082	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926550008083	Walker A/P-loop; other site
926550008084	ATP binding site [chemical binding]; other site
926550008085	Q-loop/lid; other site
926550008086	ABC transporter signature motif; other site
926550008087	Walker B; other site
926550008088	D-loop; other site
926550008089	H-loop/switch region; other site
926550008090	TOBE domain; Region: TOBE_2; pfam08402
926550008091	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550008092	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
926550008093	putative N- and C-terminal domain interface [polypeptide binding]; other site
926550008094	putative active site [active]
926550008095	MgATP binding site [chemical binding]; other site
926550008096	catalytic site [active]
926550008097	metal binding site [ion binding]; metal-binding site
926550008098	putative xylulose binding site [chemical binding]; other site
926550008099	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_10; cd12171
926550008100	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
926550008101	putative ligand binding site [chemical binding]; other site
926550008102	putative NAD binding site [chemical binding]; other site
926550008103	catalytic site [active]
926550008104	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550008105	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
926550008106	N- and C-terminal domain interface [polypeptide binding]; other site
926550008107	putative active site [active]
926550008108	MgATP binding site [chemical binding]; other site
926550008109	catalytic site [active]
926550008110	metal binding site [ion binding]; metal-binding site
926550008111	putative xylulose binding site [chemical binding]; other site
926550008112	putative homodimer interface [polypeptide binding]; other site
926550008113	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550008114	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550008115	NAD(P) binding site [chemical binding]; other site
926550008116	active site
926550008117	Ribulose kinase [Energy production and conversion]; Region: AraB; COG1069
926550008118	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550008119	nucleotide binding site [chemical binding]; other site
926550008120	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596
926550008121	active site
926550008122	intersubunit interface [polypeptide binding]; other site
926550008123	Zn2+ binding site [ion binding]; other site
926550008124	Glycerol-1-phosphate dehydrogenase (G1PDH) catalyzes the reversible reduction of dihydroxyacetone phosphate (DHAP) to glycerol-1-phosphate (G1P) in an NADH-dependent manner; Region: G1PDH; cd08175
926550008125	active site
926550008126	metal binding site [ion binding]; metal-binding site
926550008127	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
926550008128	Uncharacterized conserved protein [Function unknown]; Region: COG0398
926550008129	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550008130	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550008131	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
926550008132	Walker A/P-loop; other site
926550008133	ATP binding site [chemical binding]; other site
926550008134	Q-loop/lid; other site
926550008135	ABC transporter signature motif; other site
926550008136	Walker B; other site
926550008137	D-loop; other site
926550008138	H-loop/switch region; other site
926550008139	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550008140	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550008141	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550008142	Walker A/P-loop; other site
926550008143	ATP binding site [chemical binding]; other site
926550008144	Q-loop/lid; other site
926550008145	ABC transporter signature motif; other site
926550008146	Walker B; other site
926550008147	D-loop; other site
926550008148	H-loop/switch region; other site
926550008149	recombinase A; Provisional; Region: recA; PRK09354
926550008150	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
926550008151	hexamer interface [polypeptide binding]; other site
926550008152	Walker A motif; other site
926550008153	ATP binding site [chemical binding]; other site
926550008154	Walker B motif; other site
926550008155	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
926550008156	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
926550008157	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
926550008158	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550008159	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550008160	NAD(P) binding site [chemical binding]; other site
926550008161	active site
926550008162	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
926550008163	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
926550008164	substrate-cofactor binding pocket; other site
926550008165	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550008166	catalytic residue [active]
926550008167	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926550008168	non-specific DNA binding site [nucleotide binding]; other site
926550008169	salt bridge; other site
926550008170	sequence-specific DNA binding site [nucleotide binding]; other site
926550008171	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550008172	binding surface
926550008173	TPR motif; other site
926550008174	TPR repeat; Region: TPR_11; pfam13414
926550008175	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550008176	TPR motif; other site
926550008177	binding surface
926550008178	TPR repeat; Region: TPR_11; pfam13414
926550008179	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
926550008180	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
926550008181	Cytochrome c552; Region: Cytochrom_C552; pfam02335
926550008182	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550008183	acetate--CoA ligase; Region: Ac_CoA_lig_AcsA; TIGR02188
926550008184	Domain of unknown function (DUF3448); Region: DUF3448; pfam11930
926550008185	Uncharacterized acyl-CoA synthetase subfamily similar to Acetoacetyl-CoA synthetase; Region: AACS_like; cd05968
926550008186	acyl-activating enzyme (AAE) consensus motif; other site
926550008187	putative AMP binding site [chemical binding]; other site
926550008188	putative active site [active]
926550008189	putative CoA binding site [chemical binding]; other site
926550008190	Acetyl xylan esterase (AXE1); Region: AXE1; pfam05448
926550008191	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
926550008192	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
926550008193	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
926550008194	heterodimer interface [polypeptide binding]; other site
926550008195	active site
926550008196	FMN binding site [chemical binding]; other site
926550008197	homodimer interface [polypeptide binding]; other site
926550008198	substrate binding site [chemical binding]; other site
926550008199	bifunctional orotidine 5'-phosphate decarboxylase/orotate phosphoribosyltransferase protein; Validated; Region: PRK05500
926550008200	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
926550008201	active site
926550008202	dimer interface [polypeptide binding]; other site
926550008203	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550008204	active site
926550008205	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550008206	catalytic core [active]
926550008207	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
926550008208	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
926550008209	active site
926550008210	Uncharacterized protein family UPF0047; Region: UPF0047; pfam01894
926550008211	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
926550008212	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550008213	Coenzyme A binding pocket [chemical binding]; other site
926550008214	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
926550008215	dimer interface [polypeptide binding]; other site
926550008216	substrate binding site [chemical binding]; other site
926550008217	metal binding sites [ion binding]; metal-binding site
926550008218	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550008219	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550008220	putative substrate translocation pore; other site
926550008221	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
926550008222	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
926550008223	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
926550008224	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550008225	Bacterial Bile acid CoA ligases and similar proteins; Region: BACL_like; cd05929
926550008226	acyl-activating enzyme (AAE) consensus motif; other site
926550008227	acyl-activating enzyme (AAE) consensus motif; other site
926550008228	putative AMP binding site [chemical binding]; other site
926550008229	putative active site [active]
926550008230	putative CoA binding site [chemical binding]; other site
926550008231	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
926550008232	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
926550008233	dimer interface [polypeptide binding]; other site
926550008234	active site
926550008235	CoA binding pocket [chemical binding]; other site
926550008236	(R)-hydratase [(R)-specific enoyl-CoA hydratase] catalyzes the hydration of trans-2-enoyl CoA to (R)-3-hydroxyacyl-CoA as part of the PHA (polyhydroxyalkanoate) biosynthetic pathway. (R)-hydratase contains a hot-dog fold similar to those of thioesterase...; Region: R_hydratase; cd03449
926550008237	dimer interaction site [polypeptide binding]; other site
926550008238	substrate-binding tunnel; other site
926550008239	active site
926550008240	catalytic site [active]
926550008241	substrate binding site [chemical binding]; other site
926550008242	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550008243	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550008244	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550008245	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
926550008246	Adenosine deaminase [Nucleotide transport and metabolism]; Region: Add; COG1816
926550008247	adenosine deaminase; Provisional; Region: PRK09358
926550008248	active site
926550008249	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550008250	Fasciclin domain; Region: Fasciclin; pfam02469
926550008251	Secreted and surface protein containing fasciclin-like repeats [Cell envelope biogenesis, outer membrane]; Region: COG2335
926550008252	Fasciclin domain; Region: Fasciclin; pfam02469
926550008253	DNA-directed RNA polymerase specialized sigma subunit [Transcription]; Region: FliA; COG1191
926550008254	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
926550008255	active site
926550008256	phosphorylation site [posttranslational modification]
926550008257	intermolecular recognition site; other site
926550008258	dimerization interface [polypeptide binding]; other site
926550008259	Domain of unknown function (DUF309); Region: DUF309; pfam03745
926550008260	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
926550008261	Divergent PAP2 family; Region: DUF212; pfam02681
926550008262	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
926550008263	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926550008264	B12 binding site [chemical binding]; other site
926550008265	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550008266	FeS/SAM binding site; other site
926550008267	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008268	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008269	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008270	Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms]; Region: COG1819
926550008271	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
926550008272	homodimer interface [polypeptide binding]; other site
926550008273	active site
926550008274	TDP-binding site; other site
926550008275	acceptor substrate-binding pocket; other site
926550008276	Planctomycete cytochrome C; Region: PSCyt1; pfam07635
926550008277	putative membrane-bound dehydrogenase domain; Region: Piru_Ver_Nterm; TIGR02604
926550008278	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
926550008279	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
926550008280	active site
926550008281	Riboflavin kinase; Region: Flavokinase; pfam01687
926550008282	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
926550008283	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
926550008284	RNA binding site [nucleotide binding]; other site
926550008285	active site
926550008286	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
926550008287	DHH family; Region: DHH; pfam01368
926550008288	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
926550008289	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
926550008290	Putative zinc ribbon domain; Region: DUF164; pfam02591
926550008291	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
926550008292	Peptidase S8 family domain in Vpr-like proteins; Region: Peptidases_S8_subtilisin_Vpr-like; cd07474
926550008293	catalytic triad [active]
926550008294	putative active site [active]
926550008295	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
926550008296	generic binding surface I; other site
926550008297	generic binding surface II; other site
926550008298	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
926550008299	putative catalytic site [active]
926550008300	putative metal binding site [ion binding]; other site
926550008301	putative phosphate binding site [ion binding]; other site
926550008302	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550008303	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550008304	active site
926550008305	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
926550008306	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
926550008307	minor groove reading motif; other site
926550008308	helix-hairpin-helix signature motif; other site
926550008309	substrate binding pocket [chemical binding]; other site
926550008310	active site
926550008311	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
926550008312	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
926550008313	proposed catalytic triad [active]
926550008314	active site nucleophile [active]
926550008315	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
926550008316	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
926550008317	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
926550008318	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
926550008319	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
926550008320	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
926550008321	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
926550008322	Bacterial SH3 domain homologues; Region: SH3b; smart00287
926550008323	Polysulphide reductase [Energy production and conversion]; Region: COG5557; cl17901
926550008324	Nitrate reductase delta subunit; Region: Nitrate_red_del; pfam02613
926550008325	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926550008326	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550008327	molybdopterin cofactor binding site; other site
926550008328	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550008329	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926550008330	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
926550008331	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
926550008332	4Fe-4S binding domain; Region: Fer4; pfam00037
926550008333	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550008334	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550008335	active site
926550008336	phosphorylation site [posttranslational modification]
926550008337	intermolecular recognition site; other site
926550008338	dimerization interface [polypeptide binding]; other site
926550008339	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550008340	DNA binding residues [nucleotide binding]
926550008341	dimerization interface [polypeptide binding]; other site
926550008342	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
926550008343	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550008344	dimerization interface [polypeptide binding]; other site
926550008345	PAS domain S-box; Region: sensory_box; TIGR00229
926550008346	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550008347	putative active site [active]
926550008348	heme pocket [chemical binding]; other site
926550008349	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550008350	GAF domain; Region: GAF_3; pfam13492
926550008351	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550008352	Histidine kinase; Region: HisKA_3; pfam07730
926550008353	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550008354	ATP binding site [chemical binding]; other site
926550008355	Mg2+ binding site [ion binding]; other site
926550008356	G-X-G motif; other site
926550008357	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
926550008358	TRAP transporter solute receptor, TAXI family; Region: TRAP_TAXI; TIGR02122
926550008359	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
926550008360	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550008361	Domain of unknown function (DUF4091); Region: DUF4091; pfam13320
926550008362	diphosphomevalonate decarboxylase; Region: PLN02407
926550008363	Mevalonate pyrophosphate decarboxylase [Lipid metabolism]; Region: MVD1; COG3407
926550008364	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550008365	Uncharacterized conserved protein [Function unknown]; Region: COG3379
926550008366	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
926550008367	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550008368	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550008369	Branched-chain amino acid transport protein (AzlD); Region: AzlD; cl00735
926550008370	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
926550008371	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926550008372	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550008373	S-adenosylmethionine binding site [chemical binding]; other site
926550008374	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
926550008375	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550008376	DNA-binding site [nucleotide binding]; DNA binding site
926550008377	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550008378	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550008379	homodimer interface [polypeptide binding]; other site
926550008380	catalytic residue [active]
926550008381	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
926550008382	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
926550008383	generic binding surface II; other site
926550008384	generic binding surface I; other site
926550008385	TPR repeat; Region: TPR_11; pfam13414
926550008386	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550008387	binding surface
926550008388	TPR motif; other site
926550008389	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550008390	Bacterial SH3 domain; Region: SH3_3; cl17532
926550008391	galactarate dehydratase; Region: galactar-dH20; TIGR03248
926550008392	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
926550008393	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
926550008394	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; cl17802
926550008395	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; cl17802
926550008396	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
926550008397	NAD(P) binding pocket [chemical binding]; other site
926550008398	Ribosome-binding factor A; Region: RBFA; pfam02033
926550008399	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
926550008400	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
926550008401	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
926550008402	G1 box; other site
926550008403	putative GEF interaction site [polypeptide binding]; other site
926550008404	GTP/Mg2+ binding site [chemical binding]; other site
926550008405	Switch I region; other site
926550008406	G2 box; other site
926550008407	G3 box; other site
926550008408	Switch II region; other site
926550008409	G4 box; other site
926550008410	G5 box; other site
926550008411	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
926550008412	Translation-initiation factor 2; Region: IF-2; pfam11987
926550008413	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
926550008414	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
926550008415	putative RNA binding cleft [nucleotide binding]; other site
926550008416	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
926550008417	NusA N-terminal domain; Region: NusA_N; pfam08529
926550008418	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
926550008419	RNA binding site [nucleotide binding]; other site
926550008420	homodimer interface [polypeptide binding]; other site
926550008421	NusA-like KH domain; Region: KH_5; pfam13184
926550008422	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
926550008423	G-X-X-G motif; other site
926550008424	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
926550008425	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
926550008426	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
926550008427	TPP-binding site [chemical binding]; other site
926550008428	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
926550008429	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
926550008430	dimer interface [polypeptide binding]; other site
926550008431	PYR/PP interface [polypeptide binding]; other site
926550008432	TPP binding site [chemical binding]; other site
926550008433	substrate binding site [chemical binding]; other site
926550008434	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926550008435	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
926550008436	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
926550008437	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008438	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008439	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008440	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
926550008441	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550008442	putative substrate translocation pore; other site
926550008443	Myo-inositol-1-phosphate synthase [Lipid metabolism]; Region: INO1; COG1260
926550008444	Myo-inositol-1-phosphate synthase; Region: NAD_binding_5; cl00554
926550008445	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550008446	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550008447	DNA binding site [nucleotide binding]
926550008448	domain linker motif; other site
926550008449	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550008450	dimerization interface [polypeptide binding]; other site
926550008451	ligand binding site [chemical binding]; other site
926550008452	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
926550008453	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926550008454	Putative heavy-metal-binding; Region: YbjQ_1; cl00426
926550008455	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550008456	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926550008457	Prokaryotic protein of unknown function (DUF849); Region: DUF849; pfam05853
926550008458	serine O-acetyltransferase; Region: cysE; TIGR01172
926550008459	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
926550008460	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
926550008461	trimer interface [polypeptide binding]; other site
926550008462	active site
926550008463	substrate binding site [chemical binding]; other site
926550008464	CoA binding site [chemical binding]; other site
926550008465	HEPN domain; Region: HEPN; pfam05168
926550008466	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550008467	active site
926550008468	NTP binding site [chemical binding]; other site
926550008469	metal binding triad [ion binding]; metal-binding site
926550008470	antibiotic binding site [chemical binding]; other site
926550008471	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
926550008472	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008473	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008474	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008475	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550008476	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008477	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008478	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008479	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550008480	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550008481	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550008482	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550008483	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550008484	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550008485	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550008486	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550008487	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550008488	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550008489	Walker A/P-loop; other site
926550008490	ATP binding site [chemical binding]; other site
926550008491	Q-loop/lid; other site
926550008492	ABC transporter signature motif; other site
926550008493	Walker B; other site
926550008494	D-loop; other site
926550008495	H-loop/switch region; other site
926550008496	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550008497	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550008498	TM-ABC transporter signature motif; other site
926550008499	Periplasmic sugar-binding domain of uncharacterized ABC-type transport systems; Region: PBP1_ABC_sugar_binding_like_4; cd06312
926550008500	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550008501	putative ligand binding site [chemical binding]; other site
926550008502	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550008503	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3335
926550008504	Integrase core domain; Region: rve_3; cl15866
926550008505	Homeodomain-like domain; Region: HTH_23; cl17451
926550008506	Winged helix-turn helix; Region: HTH_29; pfam13551
926550008507	Homeodomain-like domain; Region: HTH_32; pfam13565
926550008508	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008509	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008510	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008511	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550008512	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008513	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008514	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008515	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550008516	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008517	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008518	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008519	short chain dehydrogenase; Provisional; Region: PRK06198
926550008520	classical (c) SDRs; Region: SDR_c; cd05233
926550008521	NAD(P) binding site [chemical binding]; other site
926550008522	active site
926550008523	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008524	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008525	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008526	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550008527	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550008528	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550008529	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550008530	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550008531	TM-ABC transporter signature motif; other site
926550008532	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550008533	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550008534	Walker A/P-loop; other site
926550008535	ATP binding site [chemical binding]; other site
926550008536	Q-loop/lid; other site
926550008537	ABC transporter signature motif; other site
926550008538	Walker B; other site
926550008539	D-loop; other site
926550008540	H-loop/switch region; other site
926550008541	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550008542	Periplasmic binding proteins specific to rhizopines; Region: PBP1_rhizopine_binding_like; cd06301
926550008543	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550008544	putative ligand binding site [chemical binding]; other site
926550008545	Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2; Region: ALDH_F6_MMSDH; cd07085
926550008546	methylmalonic acid semialdehyde dehydrogenase; Region: MMSDH; TIGR01722
926550008547	tetrameric interface [polypeptide binding]; other site
926550008548	NAD binding site [chemical binding]; other site
926550008549	catalytic residues [active]
926550008550	Acetolactate synthase [Amino acid transport and metabolism]; Region: COG3962
926550008551	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926550008552	PYR/PP interface [polypeptide binding]; other site
926550008553	dimer interface [polypeptide binding]; other site
926550008554	TPP binding site [chemical binding]; other site
926550008555	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926550008556	Thiamine pyrophosphate (TPP) family, IolD subfamily, TPP-binding module; composed of proteins similar to Rhizobium leguminosarum bv. viciae IolD. IolD plays an important role in myo-inositol catabolism; Region: TPP_IolD; cd02003
926550008557	TPP-binding site; other site
926550008558	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926550008559	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550008560	substrate binding site [chemical binding]; other site
926550008561	ATP binding site [chemical binding]; other site
926550008562	KduI/IolB family; Region: KduI; pfam04962
926550008563	Transaldolase; Region: Transaldolase; pfam00923
926550008564	catalytic residue [active]
926550008565	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550008566	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550008567	DNA binding site [nucleotide binding]
926550008568	domain linker motif; other site
926550008569	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550008570	dimerization interface [polypeptide binding]; other site
926550008571	ligand binding site [chemical binding]; other site
926550008572	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550008573	active site
926550008574	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550008575	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550008576	Peptidase C25 family N-terminal domain, found in Arg-gingipain (Rgp), Lys-gingipain (Kgp) and related proteins; Region: Peptidase_C25_N; cl03181
926550008577	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550008578	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
926550008579	Interdomain contacts; other site
926550008580	Cytokine receptor motif; other site
926550008581	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
926550008582	Interdomain contacts; other site
926550008583	Cytokine receptor motif; other site
926550008584	Peptidase C13 family; Region: Peptidase_C13; cl02159
926550008585	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550008586	NurA nuclease; Region: NurA; smart00933
926550008587	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926550008588	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_5; cd07583
926550008589	putative active site [active]
926550008590	catalytic triad [active]
926550008591	putative dimer interface [polypeptide binding]; other site
926550008592	Bacterial SH3 domain; Region: SH3_3; cl17532
926550008593	Bacterial SH3 domain; Region: SH3_3; cl17532
926550008594	Bacterial SH3 domain; Region: SH3_3; cl17532
926550008595	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550008596	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550008597	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
926550008598	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
926550008599	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550008600	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008601	dimer interface [polypeptide binding]; other site
926550008602	conserved gate region; other site
926550008603	putative PBP binding loops; other site
926550008604	ABC-ATPase subunit interface; other site
926550008605	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
926550008606	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008607	dimer interface [polypeptide binding]; other site
926550008608	conserved gate region; other site
926550008609	putative PBP binding loops; other site
926550008610	ABC-ATPase subunit interface; other site
926550008611	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550008612	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550008613	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550008614	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550008615	DNA binding site [nucleotide binding]
926550008616	domain linker motif; other site
926550008617	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550008618	ligand binding site [chemical binding]; other site
926550008619	dimerization interface [polypeptide binding]; other site
926550008620	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550008621	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550008622	Walker A/P-loop; other site
926550008623	ATP binding site [chemical binding]; other site
926550008624	Q-loop/lid; other site
926550008625	ABC transporter signature motif; other site
926550008626	Walker B; other site
926550008627	D-loop; other site
926550008628	H-loop/switch region; other site
926550008629	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550008630	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550008631	Walker A/P-loop; other site
926550008632	ATP binding site [chemical binding]; other site
926550008633	Q-loop/lid; other site
926550008634	ABC transporter signature motif; other site
926550008635	Walker B; other site
926550008636	D-loop; other site
926550008637	H-loop/switch region; other site
926550008638	Acidobacterial duplicated orphan permease; Region: ADOP; TIGR03434
926550008639	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
926550008640	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550008641	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
926550008642	3-isopropylmalate dehydratase, small subunit; Region: leuD; TIGR00171
926550008643	substrate binding site [chemical binding]; other site
926550008644	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
926550008645	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
926550008646	substrate binding site [chemical binding]; other site
926550008647	ligand binding site [chemical binding]; other site
926550008648	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
926550008649	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
926550008650	active site
926550008651	dimer interface [polypeptide binding]; other site
926550008652	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
926550008653	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
926550008654	active site
926550008655	FMN binding site [chemical binding]; other site
926550008656	substrate binding site [chemical binding]; other site
926550008657	3Fe-4S cluster binding site [ion binding]; other site
926550008658	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
926550008659	domain interface; other site
926550008660	DinB superfamily; Region: DinB_2; pfam12867
926550008661	Predicted sensor domain [Signal transduction mechanisms / Transcription]; Region: PocR; COG4936
926550008662	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550008663	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550008664	ATP binding site [chemical binding]; other site
926550008665	Mg2+ binding site [ion binding]; other site
926550008666	G-X-G motif; other site
926550008667	Response regulator receiver domain; Region: Response_reg; pfam00072
926550008668	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550008669	active site
926550008670	phosphorylation site [posttranslational modification]
926550008671	intermolecular recognition site; other site
926550008672	dimerization interface [polypeptide binding]; other site
926550008673	GAF domain; Region: GAF_3; pfam13492
926550008674	GAF domain; Region: GAF_2; pfam13185
926550008675	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550008676	GAF domain; Region: GAF; cl17456
926550008677	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550008678	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550008679	GAF domain; Region: GAF_2; pfam13185
926550008680	GAF domain; Region: GAF; pfam01590
926550008681	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550008682	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550008683	ATP binding site [chemical binding]; other site
926550008684	Mg2+ binding site [ion binding]; other site
926550008685	G-X-G motif; other site
926550008686	Response regulator receiver domain; Region: Response_reg; pfam00072
926550008687	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550008688	active site
926550008689	phosphorylation site [posttranslational modification]
926550008690	intermolecular recognition site; other site
926550008691	dimerization interface [polypeptide binding]; other site
926550008692	Phosphotransferase enzyme family; Region: APH; pfam01636
926550008693	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
926550008694	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
926550008695	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
926550008696	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
926550008697	ABC-ATPase subunit  interface; other site
926550008698	dimer interface [polypeptide binding]; other site
926550008699	putative PBP binding regions; other site
926550008700	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
926550008701	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
926550008702	ABC-ATPase subunit  interface; other site
926550008703	dimer interface [polypeptide binding]; other site
926550008704	putative PBP binding regions; other site
926550008705	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
926550008706	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
926550008707	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
926550008708	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
926550008709	intersubunit interface [polypeptide binding]; other site
926550008710	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
926550008711	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
926550008712	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
926550008713	FeoA domain; Region: FeoA; pfam04023
926550008714	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
926550008715	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550008716	catalytic residue [active]
926550008717	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
926550008718	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550008719	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550008720	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550008721	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550008722	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550008723	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550008724	Protein of unknown function (DUF433); Region: DUF433; cl01030
926550008725	DinB superfamily; Region: DinB_2; pfam12867
926550008726	LysE type translocator; Region: LysE; cl00565
926550008727	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
926550008728	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550008729	catalytic residue [active]
926550008730	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
926550008731	ATP binding site [chemical binding]; other site
926550008732	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550008733	active site
926550008734	uncharacterized ygcE-like proteins; Region: FGGY_ygcE_like; cd07779
926550008735	putative N- and C-terminal domain interface [polypeptide binding]; other site
926550008736	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550008737	putative active site [active]
926550008738	MgATP binding site [chemical binding]; other site
926550008739	catalytic site [active]
926550008740	metal binding site [ion binding]; metal-binding site
926550008741	putative carbohydrate binding site [chemical binding]; other site
926550008742	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550008743	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550008744	NAD(P) binding site [chemical binding]; other site
926550008745	MarR family; Region: MarR_2; cl17246
926550008746	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926550008747	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926550008748	glycerol-3-phosphate dehydrogenase (NAD(+)); Region: glycerol3P_DH; TIGR03376
926550008749	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
926550008750	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
926550008751	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926550008752	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH2; cd08183
926550008753	putative active site [active]
926550008754	metal binding site [ion binding]; metal-binding site
926550008755	short chain dehydrogenase; Provisional; Region: PRK06841
926550008756	classical (c) SDRs; Region: SDR_c; cd05233
926550008757	NAD(P) binding site [chemical binding]; other site
926550008758	active site
926550008759	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550008760	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008761	dimer interface [polypeptide binding]; other site
926550008762	conserved gate region; other site
926550008763	putative PBP binding loops; other site
926550008764	ABC-ATPase subunit interface; other site
926550008765	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550008766	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008767	dimer interface [polypeptide binding]; other site
926550008768	conserved gate region; other site
926550008769	putative PBP binding loops; other site
926550008770	ABC-ATPase subunit interface; other site
926550008771	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926550008772	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550008773	Walker A/P-loop; other site
926550008774	ATP binding site [chemical binding]; other site
926550008775	Q-loop/lid; other site
926550008776	ABC transporter signature motif; other site
926550008777	Walker B; other site
926550008778	D-loop; other site
926550008779	H-loop/switch region; other site
926550008780	TOBE domain; Region: TOBE_2; pfam08402
926550008781	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926550008782	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
926550008783	Walker A/P-loop; other site
926550008784	ATP binding site [chemical binding]; other site
926550008785	Q-loop/lid; other site
926550008786	ABC transporter signature motif; other site
926550008787	Walker B; other site
926550008788	D-loop; other site
926550008789	H-loop/switch region; other site
926550008790	TOBE domain; Region: TOBE_2; pfam08402
926550008791	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
926550008792	Dak1 domain; Region: Dak1; pfam02733
926550008793	DAK2 domain; Region: Dak2; cl03685
926550008794	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
926550008795	dihydroxyacetone kinase, phosphotransfer subunit; Region: dha_pts; TIGR02364
926550008796	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
926550008797	dimerization domain swap beta strand [polypeptide binding]; other site
926550008798	regulatory protein interface [polypeptide binding]; other site
926550008799	active site
926550008800	regulatory phosphorylation site [posttranslational modification]; other site
926550008801	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
926550008802	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
926550008803	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926550008804	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926550008805	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
926550008806	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550008807	substrate binding site [chemical binding]; other site
926550008808	ATP binding site [chemical binding]; other site
926550008809	Ribulose bisphosphate carboxylase like proteins (RLPs) similar to R.rubrum RLP; Region: RLP_RrRLP; cd08210
926550008810	dimer interface [polypeptide binding]; other site
926550008811	active site
926550008812	catalytic residue [active]
926550008813	metal binding site [ion binding]; metal-binding site
926550008814	Cupin domain; Region: Cupin_2; pfam07883
926550008815	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481; cl10557
926550008816	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
926550008817	DAK2 domain; Region: Dak2; pfam02734
926550008818	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
926550008819	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
926550008820	X25 domain of Bacillus acidopullulyticus pullulanase and similar proteins; Region: X25_BaPul_like; cd12962
926550008821	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
926550008822	homodimer interface [polypeptide binding]; other site
926550008823	maltodextrin glucosidase; Provisional; Region: PRK10785
926550008824	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
926550008825	active site
926550008826	homodimer interface [polypeptide binding]; other site
926550008827	catalytic site [active]
926550008828	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
926550008829	Interdomain contacts; other site
926550008830	Cytokine receptor motif; other site
926550008831	Starch binding domain; Region: CBM_2; smart01065
926550008832	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
926550008833	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550008834	inhibitor-cofactor binding pocket; inhibition site
926550008835	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550008836	catalytic residue [active]
926550008837	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926550008838	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550008839	DNA-binding site [nucleotide binding]; DNA binding site
926550008840	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926550008841	BtpA family; Region: BtpA; cl00440
926550008842	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550008843	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
926550008844	N- and C-terminal domain interface [polypeptide binding]; other site
926550008845	putative active site [active]
926550008846	MgATP binding site [chemical binding]; other site
926550008847	catalytic site [active]
926550008848	metal binding site [ion binding]; metal-binding site
926550008849	putative xylulose binding site [chemical binding]; other site
926550008850	putative homodimer interface [polypeptide binding]; other site
926550008851	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550008852	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550008853	NAD(P) binding site [chemical binding]; other site
926550008854	active site
926550008855	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550008856	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550008857	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008858	dimer interface [polypeptide binding]; other site
926550008859	conserved gate region; other site
926550008860	putative PBP binding loops; other site
926550008861	ABC-ATPase subunit interface; other site
926550008862	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550008863	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550008864	dimer interface [polypeptide binding]; other site
926550008865	conserved gate region; other site
926550008866	putative PBP binding loops; other site
926550008867	ABC-ATPase subunit interface; other site
926550008868	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
926550008869	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926550008870	active site
926550008871	dimerization interface [polypeptide binding]; other site
926550008872	Peptidase family C69; Region: Peptidase_C69; cl17793
926550008873	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550008874	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
926550008875	Peptidase S8 family domain, uncharacterized subfamily 3; Region: Peptidases_S8_3; cd04852
926550008876	active site
926550008877	catalytic triad [active]
926550008878	PA_subtilisin_like: Protease-associated domain containing subtilisin-like proteases. This group contains various PA domain-containing subtilisin-like proteases including melon cucumisin, Arabidopsis thaliana Ara12, a nodule specific serine protease from...; Region: PA_subtilisin_like; cd02120
926550008879	PA/protease or protease-like domain interface [polypeptide binding]; other site
926550008880	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550008881	catalytic residues [active]
926550008882	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550008883	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cd00190
926550008884	active site
926550008885	substrate binding sites [chemical binding]; other site
926550008886	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
926550008887	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
926550008888	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550008889	catalytic residue [active]
926550008890	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
926550008891	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
926550008892	substrate binding site [chemical binding]; other site
926550008893	active site
926550008894	catalytic residues [active]
926550008895	heterodimer interface [polypeptide binding]; other site
926550008896	Hydrolase of X-linked nucleoside diphosphate N terminal; Region: Nudix_N; pfam12535
926550008897	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
926550008898	nudix motif; other site
926550008899	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
926550008900	EamA-like transporter family; Region: EamA; pfam00892
926550008901	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding [General function prediction only]; Region: COG5516
926550008902	Protein of unknown function (DUF1470); Region: DUF1470; pfam07336
926550008903	CGNR zinc finger; Region: zf-CGNR; pfam11706
926550008904	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
926550008905	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550008906	Coenzyme A binding pocket [chemical binding]; other site
926550008907	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550008908	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550008909	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550008910	catalytic residues [active]
926550008911	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550008912	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550008913	ligand binding site [chemical binding]; other site
926550008914	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550008915	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550008916	TM-ABC transporter signature motif; other site
926550008917	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550008918	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550008919	Walker A/P-loop; other site
926550008920	ATP binding site [chemical binding]; other site
926550008921	Q-loop/lid; other site
926550008922	ABC transporter signature motif; other site
926550008923	Walker B; other site
926550008924	D-loop; other site
926550008925	H-loop/switch region; other site
926550008926	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550008927	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550008928	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550008929	DNA binding site [nucleotide binding]
926550008930	domain linker motif; other site
926550008931	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
926550008932	ligand binding site [chemical binding]; other site
926550008933	dimerization interface (open form) [polypeptide binding]; other site
926550008934	dimerization interface (closed form) [polypeptide binding]; other site
926550008935	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
926550008936	Amidase; Region: Amidase; cl11426
926550008937	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
926550008938	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
926550008939	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
926550008940	NADP binding site [chemical binding]; other site
926550008941	dimer interface [polypeptide binding]; other site
926550008942	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926550008943	active site
926550008944	PQQ-like domain; Region: PQQ_2; pfam13360
926550008945	Trp docking motif [polypeptide binding]; other site
926550008946	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550008947	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
926550008948	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
926550008949	dimer interface [polypeptide binding]; other site
926550008950	putative functional site; other site
926550008951	putative MPT binding site; other site
926550008952	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
926550008953	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550008954	active site
926550008955	catalytic residues [active]
926550008956	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
926550008957	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550008958	Walker A/P-loop; other site
926550008959	ATP binding site [chemical binding]; other site
926550008960	Q-loop/lid; other site
926550008961	ABC transporter signature motif; other site
926550008962	Walker B; other site
926550008963	D-loop; other site
926550008964	H-loop/switch region; other site
926550008965	Protoglobin; Region: Protoglobin; pfam11563
926550008966	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
926550008967	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
926550008968	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
926550008969	dimerization interface [polypeptide binding]; other site
926550008970	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
926550008971	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
926550008972	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
926550008973	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
926550008974	RNA binding site [nucleotide binding]; other site
926550008975	allantoate amidohydrolase; Reviewed; Region: PRK09290
926550008976	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
926550008977	active site
926550008978	metal binding site [ion binding]; metal-binding site
926550008979	dimer interface [polypeptide binding]; other site
926550008980	imidazolonepropionase; Validated; Region: PRK09356
926550008981	Imidazolonepropionase/imidazolone-5-propionate hydrolase (Imidazolone-5PH) catalyzes the third step in the histidine degradation pathway, the hydrolysis of (S)-3-(5-oxo-4,5-dihydro-3H-imidazol-4-yl)propanoate to N-formimidoyl-L-glutamate. In bacteria; Region: Imidazolone-5PH; cd01296
926550008982	active site
926550008983	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926550008984	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
926550008985	active site
926550008986	nucleophile elbow; other site
926550008987	threonine synthase; Validated; Region: PRK06260
926550008988	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
926550008989	homodimer interface [polypeptide binding]; other site
926550008990	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550008991	catalytic residue [active]
926550008992	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550008993	AMP binding site [chemical binding]; other site
926550008994	active site
926550008995	acyl-activating enzyme (AAE) consensus motif; other site
926550008996	CoA binding site [chemical binding]; other site
926550008997	Eukaryotic UGPase catalyses the synthesis of UDP-Glucose; Region: UGPase_euk; cd00897
926550008998	active site
926550008999	substrate binding site; other site
926550009000	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
926550009001	Gamma-glutamyltranspeptidase; Region: G_glu_transpept; pfam01019
926550009002	Bacterial SH3 domain; Region: SH3_3; cl17532
926550009003	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550009004	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550009005	active site
926550009006	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
926550009007	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550009008	active site
926550009009	metal binding site [ion binding]; metal-binding site
926550009010	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550009011	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cd00838
926550009012	active site
926550009013	metal binding site [ion binding]; metal-binding site
926550009014	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926550009015	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
926550009016	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550009017	Walker A/P-loop; other site
926550009018	ATP binding site [chemical binding]; other site
926550009019	Q-loop/lid; other site
926550009020	ABC transporter signature motif; other site
926550009021	Walker B; other site
926550009022	D-loop; other site
926550009023	H-loop/switch region; other site
926550009024	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
926550009025	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550009026	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550009027	DNA polymerase III subunit beta; Validated; Region: PRK05643
926550009028	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
926550009029	putative DNA binding surface [nucleotide binding]; other site
926550009030	dimer interface [polypeptide binding]; other site
926550009031	beta-clamp/clamp loader binding surface; other site
926550009032	beta-clamp/translesion DNA polymerase binding surface; other site
926550009033	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550009034	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550009035	dimerization interface [polypeptide binding]; other site
926550009036	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550009037	dimer interface [polypeptide binding]; other site
926550009038	phosphorylation site [posttranslational modification]
926550009039	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009040	ATP binding site [chemical binding]; other site
926550009041	G-X-G motif; other site
926550009042	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550009043	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009044	active site
926550009045	phosphorylation site [posttranslational modification]
926550009046	intermolecular recognition site; other site
926550009047	dimerization interface [polypeptide binding]; other site
926550009048	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550009049	DNA binding site [nucleotide binding]
926550009050	Family 4 Uracil-DNA glycosylase (UDG), found exclusively in thermophilic organisms; Region: UDG_F4_TTUDGA_like; cd10030
926550009051	Fe-S cluster binding site [ion binding]; other site
926550009052	active site
926550009053	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
926550009054	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550009055	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
926550009056	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
926550009057	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
926550009058	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550009059	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
926550009060	RibD C-terminal domain; Region: RibD_C; cl17279
926550009061	phosphodiesterase YaeI; Provisional; Region: PRK11340
926550009062	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
926550009063	putative active site [active]
926550009064	putative metal binding site [ion binding]; other site
926550009065	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550009066	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550009067	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
926550009068	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550009069	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
926550009070	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550009071	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550009072	This family is most closely related to the GT1 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II); Region: GT1_ExpE7_like; cd03823
926550009073	Glycosyl transferases group 1; Region: Glyco_trans_1_2; pfam13524
926550009074	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550009075	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550009076	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550009077	L-rhamnosyltransferase; Region: rhamnosyltran; TIGR01556
926550009078	Probable Catalytic site; other site
926550009079	metal-binding site
926550009080	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
926550009081	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926550009082	O-antigen ligase like membrane protein; Region: O-antigen_lig; pfam13425
926550009083	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926550009084	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550009085	Probable Catalytic site; other site
926550009086	metal-binding site
926550009087	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
926550009088	Ligand Binding Site [chemical binding]; other site
926550009089	Molecular Tunnel; other site
926550009090	Uncharacterized membrane protein [Function unknown]; Region: COG5427; cl02250
926550009091	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
926550009092	Asp-box motif; other site
926550009093	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926550009094	active site
926550009095	PQQ-like domain; Region: PQQ_2; pfam13360
926550009096	Trp docking motif [polypeptide binding]; other site
926550009097	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
926550009098	Glycosyl transferases group 1; Region: Glyco_trans_1_4; pfam13692
926550009099	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550009100	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
926550009101	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
926550009102	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
926550009103	Family description; Region: VCBS; pfam13517
926550009104	Family description; Region: VCBS; pfam13517
926550009105	Family description; Region: VCBS; pfam13517
926550009106	Family description; Region: VCBS; pfam13517
926550009107	Family description; Region: VCBS; pfam13517
926550009108	ASPIC and UnbV; Region: UnbV_ASPIC; pfam07593
926550009109	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550009110	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550009111	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550009112	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009113	dimer interface [polypeptide binding]; other site
926550009114	conserved gate region; other site
926550009115	putative PBP binding loops; other site
926550009116	ABC-ATPase subunit interface; other site
926550009117	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009118	putative PBP binding loops; other site
926550009119	dimer interface [polypeptide binding]; other site
926550009120	ABC-ATPase subunit interface; other site
926550009121	Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only]; Region: COG1545
926550009122	DUF35 OB-fold domain; Region: DUF35; pfam01796
926550009123	Rubredoxin-like zinc ribbon domain (DUF35_N); Region: DUF35_N; pfam12172
926550009124	acetyl-CoA acetyltransferase; Provisional; Region: PRK06064
926550009125	Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2  has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal...; Region: SCP-x_thiolase; cd00829
926550009126	active site
926550009127	methionine gamma-lyase; Validated; Region: PRK07049
926550009128	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
926550009129	homodimer interface [polypeptide binding]; other site
926550009130	substrate-cofactor binding pocket; other site
926550009131	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550009132	catalytic residue [active]
926550009133	NADH(P)-binding; Region: NAD_binding_10; pfam13460
926550009134	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
926550009135	NAD binding site [chemical binding]; other site
926550009136	substrate binding site [chemical binding]; other site
926550009137	putative active site [active]
926550009138	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926550009139	MarR family; Region: MarR_2; pfam12802
926550009140	MarR family; Region: MarR_2; cl17246
926550009141	Amidohydrolase; Region: Amidohydro_2; pfam04909
926550009142	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
926550009143	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
926550009144	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550009145	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550009146	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550009147	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550009148	TM-ABC transporter signature motif; other site
926550009149	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550009150	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550009151	TM-ABC transporter signature motif; other site
926550009152	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926550009153	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550009154	Walker A/P-loop; other site
926550009155	ATP binding site [chemical binding]; other site
926550009156	Q-loop/lid; other site
926550009157	ABC transporter signature motif; other site
926550009158	Walker B; other site
926550009159	D-loop; other site
926550009160	H-loop/switch region; other site
926550009161	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550009162	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550009163	Walker A/P-loop; other site
926550009164	ATP binding site [chemical binding]; other site
926550009165	Q-loop/lid; other site
926550009166	ABC transporter signature motif; other site
926550009167	Walker B; other site
926550009168	D-loop; other site
926550009169	H-loop/switch region; other site
926550009170	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
926550009171	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
926550009172	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
926550009173	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
926550009174	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
926550009175	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550009176	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550009177	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550009178	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009179	dimer interface [polypeptide binding]; other site
926550009180	conserved gate region; other site
926550009181	putative PBP binding loops; other site
926550009182	ABC-ATPase subunit interface; other site
926550009183	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550009184	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009185	dimer interface [polypeptide binding]; other site
926550009186	conserved gate region; other site
926550009187	putative PBP binding loops; other site
926550009188	ABC-ATPase subunit interface; other site
926550009189	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550009190	Response regulator receiver domain; Region: Response_reg; pfam00072
926550009191	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009192	active site
926550009193	phosphorylation site [posttranslational modification]
926550009194	intermolecular recognition site; other site
926550009195	dimerization interface [polypeptide binding]; other site
926550009196	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550009197	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550009198	dimer interface [polypeptide binding]; other site
926550009199	phosphorylation site [posttranslational modification]
926550009200	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009201	ATP binding site [chemical binding]; other site
926550009202	Mg2+ binding site [ion binding]; other site
926550009203	G-X-G motif; other site
926550009204	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
926550009205	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009206	active site
926550009207	phosphorylation site [posttranslational modification]
926550009208	intermolecular recognition site; other site
926550009209	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550009210	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
926550009211	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
926550009212	hexamer (dimer of trimers) interface [polypeptide binding]; other site
926550009213	substrate binding site [chemical binding]; other site
926550009214	trimer interface [polypeptide binding]; other site
926550009215	Mn binding site [ion binding]; other site
926550009216	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
926550009217	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
926550009218	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cd01066
926550009219	active site
926550009220	L-ribulose-5-phosphate 4-epimerase; Validated; Region: PRK06557
926550009221	L-ribulose-5-phosphate 4-epimerase; Reviewed; Region: araD; PRK08193
926550009222	intersubunit interface [polypeptide binding]; other site
926550009223	active site
926550009224	Zn2+ binding site [ion binding]; other site
926550009225	Domain of unknown function DUF302; Region: DUF302; cl01364
926550009226	short chain dehydrogenase; Provisional; Region: PRK08219
926550009227	Tthb094 and related proteins, classical (c) SDRs; Region: Tthb094_like_SDR_c; cd11730
926550009228	NAD(P) binding site [chemical binding]; other site
926550009229	putative active site [active]
926550009230	putative GTP cyclohydrolase; Provisional; Region: PRK13674
926550009231	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
926550009232	catalytic center binding site [active]
926550009233	ATP binding site [chemical binding]; other site
926550009234	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
926550009235	homooctamer interface [polypeptide binding]; other site
926550009236	active site
926550009237	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550009238	Novel bacterial esterase that cleaves esters on halogenated cyclic compounds; Region: Esterase_713_like; cl17303
926550009239	catalytic site [active]
926550009240	TAP-like protein; Region: Abhydrolase_4; pfam08386
926550009241	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
926550009242	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550009243	Coenzyme A binding pocket [chemical binding]; other site
926550009244	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
926550009245	Dynamin family; Region: Dynamin_N; pfam00350
926550009246	G1 box; other site
926550009247	GTP/Mg2+ binding site [chemical binding]; other site
926550009248	G2 box; other site
926550009249	Switch I region; other site
926550009250	G3 box; other site
926550009251	Switch II region; other site
926550009252	G4 box; other site
926550009253	G5 box; other site
926550009254	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
926550009255	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926550009256	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
926550009257	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550009258	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
926550009259	active site
926550009260	motif I; other site
926550009261	motif II; other site
926550009262	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
926550009263	Peptidase S8 family domain in Thermitase-like proteins; Region: Peptidases_S8_Thermitase_like; cd07484
926550009264	active site
926550009265	catalytic triad [active]
926550009266	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550009267	pyruvate phosphate dikinase; Provisional; Region: PRK09279
926550009268	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
926550009269	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
926550009270	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
926550009271	Heme-copper oxidase subunit I.  Heme-copper oxidases are transmembrane protein complexes in the respiratory chains of prokaryotes and mitochondria which catalyze the reduction of O2 and simultaneously pump protons across the membrane.  The superfamily is...; Region: Heme_Cu_Oxidase_I; cl00275
926550009272	Low-spin heme binding site [chemical binding]; other site
926550009273	D-pathway; other site
926550009274	Putative water exit pathway; other site
926550009275	Binuclear center (active site) [active]
926550009276	K-pathway; other site
926550009277	Putative proton exit pathway; other site
926550009278	Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion]; Region: CyoA; COG1622
926550009279	Cytochrome C oxidase subunit II, periplasmic domain; Region: COX2; pfam00116
926550009280	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926550009281	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926550009282	Cu(I) binding site [ion binding]; other site
926550009283	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
926550009284	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
926550009285	Cu(I) binding site [ion binding]; other site
926550009286	Hydrogenase specific C-terminal endopeptidases, also called Hydrogen Maturation Proteases (H2MP). These enzymes belong to the peptidase family M52. Maturation of [FeNi] hydrogenases includes formation of the nickel metallocenter, proteolytic processing...; Region: H2MP; cl00477
926550009287	nickel binding site [ion binding]; other site
926550009288	Coenzyme F420-reducing hydrogenase, alpha subunit [Energy production and conversion]; Region: FrhA; COG3259
926550009289	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
926550009290	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
926550009291	bidirectional hydrogenase complex protein HoxU; Validated; Region: PRK07569
926550009292	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550009293	catalytic loop [active]
926550009294	iron binding site [ion binding]; other site
926550009295	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
926550009296	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
926550009297	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
926550009298	dimer interface [polypeptide binding]; other site
926550009299	[2Fe-2S] cluster binding site [ion binding]; other site
926550009300	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
926550009301	SLBB domain; Region: SLBB; pfam10531
926550009302	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
926550009303	bidirectional hydrogenase complex protein HoxE; Reviewed; Region: PRK07571
926550009304	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
926550009305	putative dimer interface [polypeptide binding]; other site
926550009306	[2Fe-2S] cluster binding site [ion binding]; other site
926550009307	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
926550009308	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550009309	FeS/SAM binding site; other site
926550009310	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550009311	Ligand Binding Site [chemical binding]; other site
926550009312	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550009313	Ligand Binding Site [chemical binding]; other site
926550009314	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550009315	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009316	active site
926550009317	phosphorylation site [posttranslational modification]
926550009318	intermolecular recognition site; other site
926550009319	dimerization interface [polypeptide binding]; other site
926550009320	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550009321	DNA binding residues [nucleotide binding]
926550009322	dimerization interface [polypeptide binding]; other site
926550009323	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550009324	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550009325	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550009326	Histidine kinase; Region: HisKA_3; pfam07730
926550009327	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009328	ATP binding site [chemical binding]; other site
926550009329	Mg2+ binding site [ion binding]; other site
926550009330	G-X-G motif; other site
926550009331	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550009332	Walker A/P-loop; other site
926550009333	ATP binding site [chemical binding]; other site
926550009334	ABC transporter; Region: ABC_tran; pfam00005
926550009335	Q-loop/lid; other site
926550009336	ABC transporter signature motif; other site
926550009337	Walker B; other site
926550009338	D-loop; other site
926550009339	H-loop/switch region; other site
926550009340	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
926550009341	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
926550009342	nucleotide binding site/active site [active]
926550009343	HIT family signature motif; other site
926550009344	catalytic residue [active]
926550009345	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550009346	D-galactonate transporter; Region: 2A0114; TIGR00893
926550009347	putative substrate translocation pore; other site
926550009348	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
926550009349	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
926550009350	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
926550009351	HD domain; Region: HD_3; pfam13023
926550009352	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550009353	Amidohydrolase; Region: Amidohydro_4; pfam13147
926550009354	active site
926550009355	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
926550009356	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
926550009357	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
926550009358	FG-GAP repeat; Region: FG-GAP; pfam01839
926550009359	Restriction endonuclease [Defense mechanisms]; Region: McrA; COG1403
926550009360	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
926550009361	active site
926550009362	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
926550009363	Rdx family; Region: Rdx; pfam10262
926550009364	Uncharacterized conserved protein [Function unknown]; Region: COG0327
926550009365	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
926550009366	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
926550009367	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
926550009368	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
926550009369	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
926550009370	putative active site [active]
926550009371	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
926550009372	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
926550009373	active site
926550009374	HIGH motif; other site
926550009375	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
926550009376	KMSKS motif; other site
926550009377	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
926550009378	tRNA binding surface [nucleotide binding]; other site
926550009379	anticodon binding site; other site
926550009380	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
926550009381	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
926550009382	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
926550009383	Uncharacterized conserved protein [Function unknown]; Region: COG3375
926550009384	RNA-binding proteins (RRM domain) [General function prediction only]; Region: COG0724
926550009385	RNA recognition motif in Helicobacter pylori HP0827 protein and similar proteins; Region: RRM_HP0827_like; cd12399
926550009386	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550009387	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550009388	putative substrate translocation pore; other site
926550009389	malonyl-CoA synthase; Validated; Region: PRK07514
926550009390	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
926550009391	acyl-activating enzyme (AAE) consensus motif; other site
926550009392	putative AMP binding site [chemical binding]; other site
926550009393	putative active site [active]
926550009394	putative CoA binding site [chemical binding]; other site
926550009395	integron integrase; Region: integrase_gron; TIGR02249
926550009396	IntI (E2) integrases, site-specific tyrosine recombinases, DNA breaking-rejoining enzymes, N- and C-terminal domains. This CD includes integrases which are components of multiresistant integrons and mediate recombination between a proximal attI site and...; Region: INT_IntI; cd01193
926550009397	Int/Topo IB signature motif; other site
926550009398	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
926550009399	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550009400	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
926550009401	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
926550009402	antitoxin MqsA for MqsR toxin; Region: MqsA; cl15819
926550009403	toxin interface [polypeptide binding]; other site
926550009404	Zn binding site [ion binding]; other site
926550009405	potential frameshift: common BLAST hit: gi|156744142|ref|YP_001434271.1| integral membrane sensor signal transduction histidine kinase
926550009406	Histidine kinase; Region: HisKA_3; pfam07730
926550009407	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009408	ATP binding site [chemical binding]; other site
926550009409	Mg2+ binding site [ion binding]; other site
926550009410	G-X-G motif; other site
926550009411	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
926550009412	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550009413	S-adenosylmethionine binding site [chemical binding]; other site
926550009414	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926550009415	DNA polymerase III subunits gamma and tau; Provisional; Region: PRK14951
926550009416	lysine biosynthesis protein LysW; Region: lysW; TIGR01206
926550009417	hypothetical protein; Provisional; Region: PRK11568
926550009418	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
926550009419	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
926550009420	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550009421	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550009422	nucleotide binding site [chemical binding]; other site
926550009423	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550009424	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
926550009425	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
926550009426	dimer interface [polypeptide binding]; other site
926550009427	active site
926550009428	Ycf46; Provisional; Region: ycf46; CHL00195
926550009429	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550009430	Walker A motif; other site
926550009431	ATP binding site [chemical binding]; other site
926550009432	Walker B motif; other site
926550009433	arginine finger; other site
926550009434	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
926550009435	DNA photolyase; Region: DNA_photolyase; pfam00875
926550009436	A subgroup of L-lactate dehydrogenases; Region: LDH_2; cd05292
926550009437	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
926550009438	NAD binding site [chemical binding]; other site
926550009439	dimer interface [polypeptide binding]; other site
926550009440	substrate binding site [chemical binding]; other site
926550009441	tetramer (dimer of dimers) interface [polypeptide binding]; other site
926550009442	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550009443	C-3',4' desaturase CrtD; Region: desat_CrtD; TIGR02733
926550009444	hydroxyglutarate oxidase; Provisional; Region: PRK11728
926550009445	START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC (SRPBCC) ligand-binding domain superfamily; Region: SRPBCC; cl14643
926550009446	hydrophobic ligand binding site; other site
926550009447	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
926550009448	TIGR01777 family protein; Region: yfcH
926550009449	putative NAD(P) binding site [chemical binding]; other site
926550009450	putative active site [active]
926550009451	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
926550009452	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
926550009453	DNA binding residues [nucleotide binding]
926550009454	B12 binding domain; Region: B12-binding_2; pfam02607
926550009455	B12 binding domain; Region: B12-binding; pfam02310
926550009456	B12 binding site [chemical binding]; other site
926550009457	Trans-Isoprenyl Diphosphate Synthases, head-to-head; Region: Trans_IPPS_HH; cd00683
926550009458	active site lid residues [active]
926550009459	substrate binding pocket [chemical binding]; other site
926550009460	catalytic residues [active]
926550009461	substrate-Mg2+ binding site; other site
926550009462	aspartate-rich region 1; other site
926550009463	aspartate-rich region 2; other site
926550009464	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
926550009465	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
926550009466	nucleotide binding pocket [chemical binding]; other site
926550009467	K-X-D-G motif; other site
926550009468	catalytic site [active]
926550009469	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
926550009470	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
926550009471	Helix-hairpin-helix motif; Region: HHH; pfam00633
926550009472	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
926550009473	Dimer interface [polypeptide binding]; other site
926550009474	Transglycosylase; Region: Transgly; pfam00912
926550009475	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
926550009476	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
926550009477	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550009478	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550009479	Bacterial Ig-like domain; Region: Big_5; pfam13205
926550009480	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
926550009481	MG2 domain; Region: A2M_N; pfam01835
926550009482	Alpha-2-macroglobulin family; Region: A2M; pfam00207
926550009483	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
926550009484	surface patch; other site
926550009485	thioester region; other site
926550009486	specificity defining residues; other site
926550009487	urocanate hydratase; Provisional; Region: PRK05414
926550009488	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14338
926550009489	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
926550009490	TRAM domain; Region: TRAM; pfam01938
926550009491	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550009492	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550009493	active site
926550009494	catalytic tetrad [active]
926550009495	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
926550009496	putative deacylase active site [active]
926550009497	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550009498	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550009499	active site
926550009500	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
926550009501	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926550009502	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550009503	S-adenosylmethionine binding site [chemical binding]; other site
926550009504	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926550009505	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926550009506	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926550009507	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926550009508	GIY-YIG domain of hypothetical proteins from archaea and their bacterial homologs; Region: GIY-YIG_COG1833; cd10441
926550009509	putative active site [active]
926550009510	putative metal binding site [ion binding]; other site
926550009511	Transcriptional regulator [Transcription]; Region: LytR; COG1316
926550009512	LytR cell envelope-related transcriptional attenuator; Region: LytR_C; pfam13399
926550009513	Uncharacterized protein family (UPF0227); Region: UPF0227; cl14886
926550009514	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550009515	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550009516	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550009517	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009518	ABC-ATPase subunit interface; other site
926550009519	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550009520	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009521	dimer interface [polypeptide binding]; other site
926550009522	conserved gate region; other site
926550009523	putative PBP binding loops; other site
926550009524	ABC-ATPase subunit interface; other site
926550009525	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550009526	classical (c) SDRs; Region: SDR_c; cd05233
926550009527	NAD(P) binding site [chemical binding]; other site
926550009528	active site
926550009529	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
926550009530	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550009531	FGGY family of carbohydrate kinases; Region: FGGY; cd00366
926550009532	N- and C-terminal domain interface [polypeptide binding]; other site
926550009533	active site
926550009534	MgATP binding site [chemical binding]; other site
926550009535	catalytic site [active]
926550009536	metal binding site [ion binding]; metal-binding site
926550009537	carbohydrate binding site [chemical binding]; other site
926550009538	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
926550009539	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
926550009540	RNA binding surface [nucleotide binding]; other site
926550009541	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
926550009542	active site
926550009543	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
926550009544	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926550009545	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
926550009546	active site
926550009547	catalytic triad [active]
926550009548	dimer interface [polypeptide binding]; other site
926550009549	Protein of unknown function (DUF402); Region: DUF402; cl00979
926550009550	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
926550009551	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
926550009552	putative active site [active]
926550009553	oxyanion strand; other site
926550009554	catalytic triad [active]
926550009555	Glycosyl hydrolase family 20 (GH20) catalytic domain of N-acetyl-beta-D-glucosaminidase (GcnA, also known as BhsA) and related proteins. GcnA  is an exoglucosidase which cleaves N-acetyl-beta-D-galactosamine (NAG) and N-acetyl-beta-D-galactosamine...; Region: GH20_GcnA-like; cd06565
926550009556	putative active site [active]
926550009557	Uncharacterized conserved protein [Function unknown]; Region: COG3743
926550009558	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550009559	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
926550009560	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
926550009561	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
926550009562	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550009563	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550009564	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550009565	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550009566	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
926550009567	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
926550009568	Beta-Casp domain; Region: Beta-Casp; smart01027
926550009569	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
926550009570	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
926550009571	polyphosphate kinase; Provisional; Region: PRK05443
926550009572	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
926550009573	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
926550009574	putative domain interface [polypeptide binding]; other site
926550009575	putative active site [active]
926550009576	catalytic site [active]
926550009577	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
926550009578	putative domain interface [polypeptide binding]; other site
926550009579	putative active site [active]
926550009580	catalytic site [active]
926550009581	drug efflux system protein MdtG; Provisional; Region: PRK09874
926550009582	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550009583	putative substrate translocation pore; other site
926550009584	Uncharacterized conserved protein [Function unknown]; Region: COG1359
926550009585	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
926550009586	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550009587	E3 interaction surface; other site
926550009588	lipoyl attachment site [posttranslational modification]; other site
926550009589	e3 binding domain; Region: E3_binding; pfam02817
926550009590	e3 binding domain; Region: E3_binding; pfam02817
926550009591	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550009592	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550009593	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
926550009594	alpha subunit interface [polypeptide binding]; other site
926550009595	TPP binding site [chemical binding]; other site
926550009596	heterodimer interface [polypeptide binding]; other site
926550009597	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550009598	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926550009599	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550009600	tetramer interface [polypeptide binding]; other site
926550009601	TPP-binding site [chemical binding]; other site
926550009602	heterodimer interface [polypeptide binding]; other site
926550009603	phosphorylation loop region [posttranslational modification]
926550009604	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
926550009605	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
926550009606	Dehydroquinase class II; Region: DHquinase_II; pfam01220
926550009607	trimer interface [polypeptide binding]; other site
926550009608	active site
926550009609	dimer interface [polypeptide binding]; other site
926550009610	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550009611	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550009612	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550009613	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550009614	Sugar diacid utilization regulator [Transcription / Signal transduction mechanisms]; Region: CdaR; COG3835
926550009615	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
926550009616	Jacalin-like lectin domain; Region: Jacalin_like; cd09302
926550009617	putative sugar binding site [chemical binding]; other site
926550009618	Uncharacterized conserved protein [Function unknown]; Region: COG3743
926550009619	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550009620	Glucuronate isomerase [Carbohydrate transport and metabolism]; Region: UxaC; COG1904
926550009621	glucuronate isomerase; Reviewed; Region: PRK02925
926550009622	Uncharacterized bacterial proteins with similarity to Aminoglycoside 3'-phosphotransferase (APH) and Choline kinase (ChoK) family members. The APH/ChoK subfamily is part of a larger superfamily that includes the catalytic domains of other kinases; Region: APH_ChoK_like_1; cd05155
926550009623	Phosphotransferase enzyme family; Region: APH; pfam01636
926550009624	putative active site [active]
926550009625	putative substrate binding site [chemical binding]; other site
926550009626	ATP binding site [chemical binding]; other site
926550009627	VPS10 domain; Region: VPS10; smart00602
926550009628	VPS10 domain; Region: VPS10; smart00602
926550009629	Glycosyl hydrolase family 10; Region: Glyco_hydro_10; cl01495
926550009630	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
926550009631	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
926550009632	NAD(P) binding site [chemical binding]; other site
926550009633	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550009634	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550009635	TM-ABC transporter signature motif; other site
926550009636	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550009637	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550009638	TM-ABC transporter signature motif; other site
926550009639	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550009640	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550009641	Walker A/P-loop; other site
926550009642	ATP binding site [chemical binding]; other site
926550009643	Q-loop/lid; other site
926550009644	ABC transporter signature motif; other site
926550009645	Walker B; other site
926550009646	D-loop; other site
926550009647	H-loop/switch region; other site
926550009648	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550009649	Periplasmic sugar-binding component of uncharacterized ABC-type transport systems that are members of the pentose/hexose sugar-binding protein family of the type I periplasmic binding protein superfamily; Region: PBP1_ABC_sugar_binding_like_1; cd06300
926550009650	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550009651	putative ligand binding site [chemical binding]; other site
926550009652	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
926550009653	active site
926550009654	substrate binding pocket [chemical binding]; other site
926550009655	homodimer interaction site [polypeptide binding]; other site
926550009656	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550009657	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550009658	NAD(P) binding site [chemical binding]; other site
926550009659	active site
926550009660	hypothetical protein; Provisional; Region: PRK02947
926550009661	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926550009662	putative active site [active]
926550009663	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550009664	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550009665	FAD dependent oxidoreductase; Region: FAD_oxidored; pfam12831
926550009666	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550009667	DNA-binding site [nucleotide binding]; DNA binding site
926550009668	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
926550009669	membrane-bound complex binding site; other site
926550009670	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
926550009671	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550009672	ATP binding site [chemical binding]; other site
926550009673	putative Mg++ binding site [ion binding]; other site
926550009674	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550009675	nucleotide binding region [chemical binding]; other site
926550009676	ATP-binding site [chemical binding]; other site
926550009677	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
926550009678	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
926550009679	dimerization interface [polypeptide binding]; other site
926550009680	ligand binding site [chemical binding]; other site
926550009681	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
926550009682	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550009683	TM-ABC transporter signature motif; other site
926550009684	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
926550009685	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
926550009686	TM-ABC transporter signature motif; other site
926550009687	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
926550009688	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
926550009689	Walker A/P-loop; other site
926550009690	ATP binding site [chemical binding]; other site
926550009691	Q-loop/lid; other site
926550009692	ABC transporter signature motif; other site
926550009693	Walker B; other site
926550009694	D-loop; other site
926550009695	H-loop/switch region; other site
926550009696	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
926550009697	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
926550009698	Walker A/P-loop; other site
926550009699	ATP binding site [chemical binding]; other site
926550009700	Q-loop/lid; other site
926550009701	ABC transporter signature motif; other site
926550009702	Walker B; other site
926550009703	D-loop; other site
926550009704	H-loop/switch region; other site
926550009705	Branched-chain amino acid ATP-binding cassette transporter; Region: BCA_ABC_TP_C; pfam12399
926550009706	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550009707	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550009708	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
926550009709	amidase catalytic site [active]
926550009710	Zn binding residues [ion binding]; other site
926550009711	substrate binding site [chemical binding]; other site
926550009712	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cl02712
926550009713	amidase catalytic site [active]
926550009714	Zn binding residues [ion binding]; other site
926550009715	substrate binding site [chemical binding]; other site
926550009716	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
926550009717	amidase catalytic site [active]
926550009718	Zn binding residues [ion binding]; other site
926550009719	substrate binding site [chemical binding]; other site
926550009720	ScpA/B protein; Region: ScpA_ScpB; cl00598
926550009721	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550009722	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550009723	active site
926550009724	catalytic tetrad [active]
926550009725	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
926550009726	dimerization interface [polypeptide binding]; other site
926550009727	putative tRNAtyr binding site [nucleotide binding]; other site
926550009728	putative active site [active]
926550009729	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
926550009730	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
926550009731	Helix-hairpin-helix motif; Region: HHH; pfam00633
926550009732	Predicted NAD/FAD-dependent oxidoreductase [General function prediction only]; Region: COG3380
926550009733	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550009734	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550009735	sugar transferase, PEP-CTERM/EpsH1 system associated; Region: stp1; TIGR03087
926550009736	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550009737	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550009738	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
926550009739	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
926550009740	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
926550009741	G1 box; other site
926550009742	putative GEF interaction site [polypeptide binding]; other site
926550009743	GTP/Mg2+ binding site [chemical binding]; other site
926550009744	Switch I region; other site
926550009745	G2 box; other site
926550009746	G3 box; other site
926550009747	Switch II region; other site
926550009748	G4 box; other site
926550009749	G5 box; other site
926550009750	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
926550009751	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
926550009752	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
926550009753	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
926550009754	Lamin Tail Domain; Region: LTD; pfam00932
926550009755	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
926550009756	putative metal binding residues [ion binding]; other site
926550009757	signature motif; other site
926550009758	dimer interface [polypeptide binding]; other site
926550009759	active site
926550009760	polyP binding site; other site
926550009761	substrate binding site [chemical binding]; other site
926550009762	acceptor-phosphate pocket; other site
926550009763	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550009764	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550009765	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550009766	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550009767	elongation factor P; Validated; Region: PRK00529
926550009768	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
926550009769	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
926550009770	RNA binding site [nucleotide binding]; other site
926550009771	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
926550009772	RNA binding site [nucleotide binding]; other site
926550009773	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
926550009774	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550009775	putative substrate translocation pore; other site
926550009776	2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1, 4-benzoquinol methylase [Coenzyme metabolism]; Region: UbiG; COG2227
926550009777	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
926550009778	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550009779	putative active site [active]
926550009780	heme pocket [chemical binding]; other site
926550009781	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550009782	dimer interface [polypeptide binding]; other site
926550009783	phosphorylation site [posttranslational modification]
926550009784	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009785	ATP binding site [chemical binding]; other site
926550009786	Mg2+ binding site [ion binding]; other site
926550009787	G-X-G motif; other site
926550009788	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550009789	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009790	active site
926550009791	phosphorylation site [posttranslational modification]
926550009792	intermolecular recognition site; other site
926550009793	dimerization interface [polypeptide binding]; other site
926550009794	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550009795	DNA binding site [nucleotide binding]
926550009796	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
926550009797	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550009798	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
926550009799	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
926550009800	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009801	dimer interface [polypeptide binding]; other site
926550009802	conserved gate region; other site
926550009803	putative PBP binding loops; other site
926550009804	ABC-ATPase subunit interface; other site
926550009805	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009806	dimer interface [polypeptide binding]; other site
926550009807	conserved gate region; other site
926550009808	putative PBP binding loops; other site
926550009809	ABC-ATPase subunit interface; other site
926550009810	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
926550009811	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
926550009812	Walker A/P-loop; other site
926550009813	ATP binding site [chemical binding]; other site
926550009814	Q-loop/lid; other site
926550009815	ABC transporter signature motif; other site
926550009816	Walker B; other site
926550009817	D-loop; other site
926550009818	H-loop/switch region; other site
926550009819	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
926550009820	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
926550009821	putative active site [active]
926550009822	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
926550009823	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
926550009824	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
926550009825	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
926550009826	Ferritin-like domain; Region: Ferritin; pfam00210
926550009827	ferroxidase diiron center [ion binding]; other site
926550009828	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
926550009829	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550009830	motif II; other site
926550009831	short chain dehydrogenase; Provisional; Region: PRK06198
926550009832	classical (c) SDRs; Region: SDR_c; cd05233
926550009833	NAD(P) binding site [chemical binding]; other site
926550009834	active site
926550009835	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550009836	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926550009837	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
926550009838	active site
926550009839	Phage integrase, N-terminal SAM-like domain; Region: Phage_integr_N; cl12235
926550009840	DNA breaking-rejoining enzymes, intergrase/recombinases, C-terminal catalytic domain. The tyrosine recombinase/integrase family share the same catalytic domain containing six conserved active site residues. The best-studied members of this diverse family...; Region: INT_REC_C; cd01182
926550009841	active site
926550009842	catalytic residues [active]
926550009843	DNA binding site [nucleotide binding]
926550009844	Int/Topo IB signature motif; other site
926550009845	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550009846	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009847	dimer interface [polypeptide binding]; other site
926550009848	conserved gate region; other site
926550009849	putative PBP binding loops; other site
926550009850	ABC-ATPase subunit interface; other site
926550009851	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550009852	dimer interface [polypeptide binding]; other site
926550009853	conserved gate region; other site
926550009854	putative PBP binding loops; other site
926550009855	ABC-ATPase subunit interface; other site
926550009856	Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: SGA1; COG3387
926550009857	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
926550009858	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
926550009859	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
926550009860	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550009861	Predicted N-acetylglucosamine kinase [Carbohydrate transport and metabolism]; Region: COG2971
926550009862	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
926550009863	Cupin domain; Region: Cupin_2; cl17218
926550009864	glucose-6-phosphate isomerase; Provisional; Region: PRK04190
926550009865	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
926550009866	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926550009867	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
926550009868	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926550009869	Acyl CoA binding protein (ACBP) binds thiol esters of long fatty acids and coenzyme A in a one-to-one binding mode with high specificity and affinity. Acyl-CoAs are important intermediates in fatty lipid synthesis and fatty acid degradation and play a...; Region: ACBP; cd00435
926550009870	acyl-CoA binding pocket [chemical binding]; other site
926550009871	CoA binding site [chemical binding]; other site
926550009872	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
926550009873	Protein of unknown function DUF58; Region: DUF58; pfam01882
926550009874	von Willebrand factor type A domain; Region: VWA_2; pfam13519
926550009875	metal ion-dependent adhesion site (MIDAS); other site
926550009876	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
926550009877	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550009878	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550009879	Peptidase family M23; Region: Peptidase_M23; pfam01551
926550009880	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550009881	PA14 domain; Region: PA14; cl08459
926550009882	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550009883	NHL repeat; Region: NHL; pfam01436
926550009884	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
926550009885	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550009886	Uncharacterized conserved protein [Function unknown]; Region: COG3391
926550009887	NHL repeat; Region: NHL; pfam01436
926550009888	NHL repeat; Region: NHL; pfam01436
926550009889	TIGR03663 family protein; Region: TIGR03663
926550009890	Uncharacterized membrane protein [Function unknown]; Region: COG5427; cl02250
926550009891	Uncharacterized membrane protein (DUF2298); Region: DUF2298; pfam10060
926550009892	Uncharacterized membrane protein [Function unknown]; Region: COG5427; cl02250
926550009893	Uncharacterized membrane protein [Function unknown]; Region: COG5427; cl02250
926550009894	Uncharacterized membrane protein (DUF2298); Region: DUF2298; pfam10060
926550009895	Uncharacterized membrane protein [Function unknown]; Region: COG5427; cl02250
926550009896	Uncharacterized membrane protein (DUF2298); Region: DUF2298; pfam10060
926550009897	Domain of unknown function (DUF348); Region: DUF348; pfam03990
926550009898	Domain of unknown function (DUF348); Region: DUF348; pfam03990
926550009899	Domain of unknown function (DUF348); Region: DUF348; pfam03990
926550009900	G5 domain; Region: G5; pfam07501
926550009901	3D domain; Region: 3D; cl01439
926550009902	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550009903	FIG, FBPase/IMPase/glpX-like domain. A superfamily of metal-dependent phosphatases with various substrates. Fructose-1,6-bisphospatase (both the major and the glpX-encoded variant) hydrolyze fructose-1,6,-bisphosphate to fructose-6-phosphate in...; Region: FIG; cl00289
926550009904	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
926550009905	active site
926550009906	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
926550009907	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
926550009908	Sulfate transporter family; Region: Sulfate_transp; pfam00916
926550009909	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
926550009910	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550009911	active site residue [active]
926550009912	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
926550009913	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550009914	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926550009915	molybdopterin cofactor binding site; other site
926550009916	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
926550009917	putative molybdopterin cofactor binding site; other site
926550009918	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
926550009919	4Fe-4S binding domain; Region: Fer4; pfam00037
926550009920	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
926550009921	DMSO reductase anchor subunit (DmsC); Region: DmsC; cl17519
926550009922	DsrE/DsrF/DrsH-like family; Region: DrsE_2; cl17453
926550009923	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
926550009924	CPxP  motif; other site
926550009925	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926550009926	active site residue [active]
926550009927	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550009928	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550009929	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009930	active site
926550009931	phosphorylation site [posttranslational modification]
926550009932	intermolecular recognition site; other site
926550009933	dimerization interface [polypeptide binding]; other site
926550009934	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550009935	DNA binding residues [nucleotide binding]
926550009936	dimerization interface [polypeptide binding]; other site
926550009937	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550009938	Histidine kinase; Region: HisKA_3; pfam07730
926550009939	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009940	ATP binding site [chemical binding]; other site
926550009941	Mg2+ binding site [ion binding]; other site
926550009942	G-X-G motif; other site
926550009943	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
926550009944	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550009945	ATP binding site [chemical binding]; other site
926550009946	Mg2+ binding site [ion binding]; other site
926550009947	G-X-G motif; other site
926550009948	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550009949	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009950	active site
926550009951	phosphorylation site [posttranslational modification]
926550009952	intermolecular recognition site; other site
926550009953	dimerization interface [polypeptide binding]; other site
926550009954	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550009955	DNA binding residues [nucleotide binding]
926550009956	dimerization interface [polypeptide binding]; other site
926550009957	Response regulator receiver domain; Region: Response_reg; pfam00072
926550009958	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550009959	active site
926550009960	phosphorylation site [posttranslational modification]
926550009961	intermolecular recognition site; other site
926550009962	dimerization interface [polypeptide binding]; other site
926550009963	glycogen synthase; Provisional; Region: glgA; PRK00654
926550009964	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
926550009965	ADP-binding pocket [chemical binding]; other site
926550009966	homodimer interface [polypeptide binding]; other site
926550009967	1,4-dihydroxy-2-naphthoate octaprenyltransferase; Validated; Region: PRK06080
926550009968	UbiA prenyltransferase family; Region: UbiA; pfam01040
926550009969	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
926550009970	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
926550009971	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
926550009972	Peptidase inhibitor I9; Region: Inhibitor_I9; pfam05922
926550009973	Peptidase S8 family domain in ProteinaseK-like proteins; Region: Peptidases_S8_PCSK9_ProteinaseK_like; cd04077
926550009974	calcium binding site 2 [ion binding]; other site
926550009975	active site
926550009976	catalytic triad [active]
926550009977	calcium binding site 1 [ion binding]; other site
926550009978	Type II cohesin domain, interaction partner of dockerin; Region: Type_II_cohesin; cd08547
926550009979	Escherichia coli UshA-like family, N-terminal metallophosphatase domain; Region: MPP_UshA_N_like; cd00845
926550009980	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
926550009981	active site
926550009982	metal binding site [ion binding]; metal-binding site
926550009983	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
926550009984	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_8; cd12167
926550009985	putative ligand binding site [chemical binding]; other site
926550009986	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926550009987	putative NAD binding site [chemical binding]; other site
926550009988	catalytic site [active]
926550009989	N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228
926550009990	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
926550009991	active site
926550009992	putative substrate binding pocket [chemical binding]; other site
926550009993	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
926550009994	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
926550009995	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
926550009996	protein binding site [polypeptide binding]; other site
926550009997	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
926550009998	Catalytic dyad [active]
926550009999	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
926550010000	SmpB-tmRNA interface; other site
926550010001	Serine dehydrogenase proteinase; Region: SDH_sah; pfam01972
926550010002	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
926550010003	active site
926550010004	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
926550010005	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
926550010006	active site
926550010007	putative substrate binding pocket [chemical binding]; other site
926550010008	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550010009	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550010010	TM-ABC transporter signature motif; other site
926550010011	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550010012	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
926550010013	TM-ABC transporter signature motif; other site
926550010014	ABC-type uncharacterized transport systems, ATPase components [General function prediction only]; Region: COG3845
926550010015	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550010016	Walker A/P-loop; other site
926550010017	ATP binding site [chemical binding]; other site
926550010018	Q-loop/lid; other site
926550010019	ABC transporter signature motif; other site
926550010020	Walker B; other site
926550010021	D-loop; other site
926550010022	H-loop/switch region; other site
926550010023	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550010024	Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein [General function prediction only]; Region: Med; COG1744
926550010025	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
926550010026	ligand binding site [chemical binding]; other site
926550010027	Peptide chain release factor 1 (eRF1) [Translation, ribosomal structure and biogenesis]; Region: eRF1; COG1503
926550010028	SpoIVFB Site-2 protease (S2P), a zinc metalloprotease (MEROPS family M50B), regulates intramembrane proteolysis (RIP), and is involved in the pro-sigmaK pathway of bacterial spore formation. In this subgroup, SpoIVFB (sporulation protein, stage IV cell...; Region: S2P-M50_SpoIVFB_CBS; cd06164
926550010029	Peptidase family M50; Region: Peptidase_M50; pfam02163
926550010030	active site
926550010031	putative substrate binding region [chemical binding]; other site
926550010032	FOG: CBS domain [General function prediction only]; Region: COG0517
926550010033	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_26; cd04639
926550010034	OsmC-like protein; Region: OsmC; pfam02566
926550010035	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
926550010036	ligand binding site [chemical binding]; other site
926550010037	NAD binding site [chemical binding]; other site
926550010038	dimerization interface [polypeptide binding]; other site
926550010039	catalytic site [active]
926550010040	Predicted membrane protein [Function unknown]; Region: COG2510
926550010041	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
926550010042	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
926550010043	active site
926550010044	putative substrate binding pocket [chemical binding]; other site
926550010045	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550010046	succinate dehydrogenase/fumarate reductase iron-sulfur subunit; Validated; Region: PRK07570
926550010047	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
926550010048	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK07573
926550010049	L-aspartate oxidase; Provisional; Region: PRK06175
926550010050	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
926550010051	Succinate:quinone oxidoreductase (SQR)-like Type B subfamily 2, transmembrane subunit; composed of proteins with similarity to the SQRs of Geobacter metallireducens and Corynebacterium glutamicum. SQR catalyzes the oxidation of succinate to fumarate...; Region: SQR_TypeB_2_TM; cd03498
926550010052	succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; Region: sdhC_b558_fam; TIGR02046
926550010053	proximal heme binding site [chemical binding]; other site
926550010054	distal heme binding site [chemical binding]; other site
926550010055	putative dimer interface [polypeptide binding]; other site
926550010056	putative Iron-sulfur protein interface [polypeptide binding]; other site
926550010057	anthranilate synthase component I; Provisional; Region: PRK13565
926550010058	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
926550010059	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
926550010060	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
926550010061	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
926550010062	active site
926550010063	HIGH motif; other site
926550010064	dimer interface [polypeptide binding]; other site
926550010065	KMSKS motif; other site
926550010066	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
926550010067	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
926550010068	glutamine binding [chemical binding]; other site
926550010069	catalytic triad [active]
926550010070	Phosphotransferase enzyme family; Region: APH; pfam01636
926550010071	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
926550010072	active site
926550010073	substrate binding site [chemical binding]; other site
926550010074	ATP binding site [chemical binding]; other site
926550010075	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
926550010076	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
926550010077	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
926550010078	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
926550010079	active site
926550010080	ribulose/triose binding site [chemical binding]; other site
926550010081	phosphate binding site [ion binding]; other site
926550010082	substrate (anthranilate) binding pocket [chemical binding]; other site
926550010083	product (indole) binding pocket [chemical binding]; other site
926550010084	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550010085	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550010086	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550010087	dimer interface [polypeptide binding]; other site
926550010088	phosphorylation site [posttranslational modification]
926550010089	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550010090	ATP binding site [chemical binding]; other site
926550010091	Mg2+ binding site [ion binding]; other site
926550010092	G-X-G motif; other site
926550010093	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550010094	cheY-homologous receiver domain; Region: REC; smart00448
926550010095	phosphorylation site [posttranslational modification]
926550010096	Response regulator receiver domain; Region: Response_reg; pfam00072
926550010097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550010098	active site
926550010099	phosphorylation site [posttranslational modification]
926550010100	intermolecular recognition site; other site
926550010101	dimerization interface [polypeptide binding]; other site
926550010102	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550010103	tyrosine decarboxylase; Region: PLN02880
926550010104	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550010105	catalytic residue [active]
926550010106	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
926550010107	active site
926550010108	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
926550010109	ABC transporter periplasmic binding protein, urea carboxylase region; Region: ABC_peri_uca; TIGR03427
926550010110	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
926550010111	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010112	dimer interface [polypeptide binding]; other site
926550010113	conserved gate region; other site
926550010114	putative PBP binding loops; other site
926550010115	ABC-ATPase subunit interface; other site
926550010116	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926550010117	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926550010118	Walker A/P-loop; other site
926550010119	ATP binding site [chemical binding]; other site
926550010120	Q-loop/lid; other site
926550010121	ABC transporter signature motif; other site
926550010122	Walker B; other site
926550010123	D-loop; other site
926550010124	H-loop/switch region; other site
926550010125	Domain of unknown function (DUF4147); Region: DUF4147; pfam13660
926550010126	Putative glycerate kinase [Carbohydrate transport and metabolism]; Region: GckA; COG2379
926550010127	MOFRL family; Region: MOFRL; pfam05161
926550010128	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550010129	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010130	dimer interface [polypeptide binding]; other site
926550010131	conserved gate region; other site
926550010132	putative PBP binding loops; other site
926550010133	ABC-ATPase subunit interface; other site
926550010134	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550010135	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010136	putative PBP binding loops; other site
926550010137	ABC-ATPase subunit interface; other site
926550010138	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550010139	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550010140	beta-phosphoglucomutase; Region: bPGM; TIGR01990
926550010141	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550010142	motif II; other site
926550010143	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
926550010144	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
926550010145	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
926550010146	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550010147	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550010148	DNA binding site [nucleotide binding]
926550010149	domain linker motif; other site
926550010150	Ligand-binding domain of DNA transcription repressors specific for raffinose (RafR) and alpha-glucosides (AglR) which are members of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_AglR_RafR_like; cd06271
926550010151	ligand binding site [chemical binding]; other site
926550010152	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
926550010153	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
926550010154	active site
926550010155	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926550010156	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
926550010157	putative active site [active]
926550010158	NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; Region: Octopine_DH; pfam02317
926550010159	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926550010160	MutL protein; Region: MutL; pfam13941
926550010161	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
926550010162	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550010163	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550010164	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010165	dimer interface [polypeptide binding]; other site
926550010166	conserved gate region; other site
926550010167	putative PBP binding loops; other site
926550010168	ABC-ATPase subunit interface; other site
926550010169	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550010170	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
926550010171	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010172	dimer interface [polypeptide binding]; other site
926550010173	conserved gate region; other site
926550010174	putative PBP binding loops; other site
926550010175	ABC-ATPase subunit interface; other site
926550010176	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550010177	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010178	Walker A/P-loop; other site
926550010179	ATP binding site [chemical binding]; other site
926550010180	Q-loop/lid; other site
926550010181	ABC transporter signature motif; other site
926550010182	Walker B; other site
926550010183	D-loop; other site
926550010184	H-loop/switch region; other site
926550010185	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
926550010186	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
926550010187	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010188	Walker A/P-loop; other site
926550010189	ATP binding site [chemical binding]; other site
926550010190	Q-loop/lid; other site
926550010191	ABC transporter signature motif; other site
926550010192	Walker B; other site
926550010193	D-loop; other site
926550010194	H-loop/switch region; other site
926550010195	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550010196	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
926550010197	active site
926550010198	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
926550010199	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
926550010200	oligomerisation interface [polypeptide binding]; other site
926550010201	mobile loop; other site
926550010202	roof hairpin; other site
926550010203	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
926550010204	catalytic residues [active]
926550010205	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550010206	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
926550010207	putative active site [active]
926550010208	heme pocket [chemical binding]; other site
926550010209	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550010210	nitrogen fixation negative regulator NifL; Region: nifL_nitrog; TIGR02938
926550010211	putative active site [active]
926550010212	heme pocket [chemical binding]; other site
926550010213	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550010214	putative active site [active]
926550010215	heme pocket [chemical binding]; other site
926550010216	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550010217	dimer interface [polypeptide binding]; other site
926550010218	phosphorylation site [posttranslational modification]
926550010219	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550010220	ATP binding site [chemical binding]; other site
926550010221	Mg2+ binding site [ion binding]; other site
926550010222	G-X-G motif; other site
926550010223	Response regulator receiver domain; Region: Response_reg; pfam00072
926550010224	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550010225	active site
926550010226	phosphorylation site [posttranslational modification]
926550010227	intermolecular recognition site; other site
926550010228	dimerization interface [polypeptide binding]; other site
926550010229	ABC-type anion transport system, duplicated permease component [Inorganic ion transport and metabolism]; Region: COG4986
926550010230	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010231	dimer interface [polypeptide binding]; other site
926550010232	conserved gate region; other site
926550010233	putative PBP binding loops; other site
926550010234	ABC-ATPase subunit interface; other site
926550010235	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010236	dimer interface [polypeptide binding]; other site
926550010237	conserved gate region; other site
926550010238	putative PBP binding loops; other site
926550010239	ABC-ATPase subunit interface; other site
926550010240	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
926550010241	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
926550010242	Walker A/P-loop; other site
926550010243	ATP binding site [chemical binding]; other site
926550010244	Q-loop/lid; other site
926550010245	ABC transporter signature motif; other site
926550010246	Walker B; other site
926550010247	D-loop; other site
926550010248	H-loop/switch region; other site
926550010249	ABC nitrate/sulfonate/bicarbonate family transporter, ATPase subunit; Region: ABC_transp; pfam09821
926550010250	camphor resistance protein CrcB; Provisional; Region: PRK14215
926550010251	PII-like signaling protein [Signal transduction mechanisms]; Region: COG1993
926550010252	FOG: CBS domain [General function prediction only]; Region: COG0517
926550010253	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection...; Region: CBS_pair_BON_assoc; cd04586
926550010254	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
926550010255	Predicted integral membrane protein [Function unknown]; Region: COG5617
926550010256	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
926550010257	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550010258	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
926550010259	FeS/SAM binding site; other site
926550010260	Protein of unknown function (DUF3307); Region: DUF3307; pfam11750
926550010261	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550010262	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550010263	ligand binding site [chemical binding]; other site
926550010264	flexible hinge region; other site
926550010265	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
926550010266	TGF-beta propeptide; Region: TGFb_propeptide; pfam00688
926550010267	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
926550010268	tartrate dehydrogenase; Region: TTC; TIGR02089
926550010269	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
926550010270	Phosphoenolpyruvate carboxylase [Energy production and conversion]; Region: Ppc; COG2352
926550010271	HAD-superfamily subfamily IIA hydrolase, TIGR01458; Region: HAD-SF-IIA-hyp3
926550010272	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550010273	active site
926550010274	motif I; other site
926550010275	motif II; other site
926550010276	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550010277	putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344
926550010278	Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941
926550010279	active site
926550010280	catalytic residues [active]
926550010281	metal binding site [ion binding]; metal-binding site
926550010282	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
926550010283	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550010284	Response regulator receiver domain; Region: Response_reg; pfam00072
926550010285	active site
926550010286	phosphorylation site [posttranslational modification]
926550010287	intermolecular recognition site; other site
926550010288	dimerization interface [polypeptide binding]; other site
926550010289	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
926550010290	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550010291	putative trimer interface [polypeptide binding]; other site
926550010292	putative CoA binding site [chemical binding]; other site
926550010293	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
926550010294	trimer interface [polypeptide binding]; other site
926550010295	active site
926550010296	substrate binding site [chemical binding]; other site
926550010297	CoA binding site [chemical binding]; other site
926550010298	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550010299	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550010300	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926550010301	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550010302	Probable Catalytic site; other site
926550010303	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550010304	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
926550010305	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
926550010306	putative metal binding site; other site
926550010307	Response regulator receiver domain; Region: Response_reg; pfam00072
926550010308	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550010309	active site
926550010310	phosphorylation site [posttranslational modification]
926550010311	intermolecular recognition site; other site
926550010312	dimerization interface [polypeptide binding]; other site
926550010313	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550010314	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550010315	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550010316	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550010317	dimer interface [polypeptide binding]; other site
926550010318	phosphorylation site [posttranslational modification]
926550010319	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550010320	ATP binding site [chemical binding]; other site
926550010321	Mg2+ binding site [ion binding]; other site
926550010322	G-X-G motif; other site
926550010323	chromosome segregation protein; Provisional; Region: PRK03918
926550010324	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550010325	Walker A/P-loop; other site
926550010326	ATP binding site [chemical binding]; other site
926550010327	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550010328	ABC transporter signature motif; other site
926550010329	Walker B; other site
926550010330	D-loop; other site
926550010331	H-loop/switch region; other site
926550010332	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
926550010333	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
926550010334	active site
926550010335	metal binding site [ion binding]; metal-binding site
926550010336	DNA binding site [nucleotide binding]
926550010337	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
926550010338	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550010339	Coenzyme A binding pocket [chemical binding]; other site
926550010340	heat shock protein GrpE; Provisional; Region: PRK14140
926550010341	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
926550010342	dimer interface [polypeptide binding]; other site
926550010343	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
926550010344	Winged helix-turn-helix transcription repressor, HrcA DNA-binding; Region: HrcA_DNA-bdg; pfam03444
926550010345	heat shock gene repressor HrcA; Region: hrcA; TIGR00331
926550010346	Undecaprenyl-phosphate glucose phosphotransferase; Region: WcaJ_sugtrans; TIGR03023
926550010347	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010348	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926550010349	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
926550010350	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
926550010351	Probable Catalytic site; other site
926550010352	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550010353	glutamate formiminotransferase; Region: FtcD; TIGR02024
926550010354	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
926550010355	Formiminotransferase domain; Region: FTCD; pfam02971
926550010356	Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]; Region: COG2348
926550010357	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
926550010358	Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis]; Region: COG2348
926550010359	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
926550010360	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
926550010361	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926550010362	B12 binding site [chemical binding]; other site
926550010363	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550010364	FeS/SAM binding site; other site
926550010365	diaminopimelate decarboxylase; Region: lysA; TIGR01048
926550010366	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
926550010367	active site
926550010368	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926550010369	substrate binding site [chemical binding]; other site
926550010370	catalytic residues [active]
926550010371	dimer interface [polypeptide binding]; other site
926550010372	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
926550010373	EamA-like transporter family; Region: EamA; pfam00892
926550010374	threonine synthase; Validated; Region: PRK08197
926550010375	Threonine synthase is a pyridoxal phosphate (PLP) dependent enzyme that catalyses the last reaction in the synthesis of  threonine from aspartate. It proceeds by converting O-phospho-L-homoserine (OPH) into threonine and inorganic phosphate. In plants; Region: Thr-synth_1; cd01563
926550010376	homodimer interface [polypeptide binding]; other site
926550010377	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550010378	catalytic residue [active]
926550010379	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
926550010380	Isocitrate dehydrogenase kinase/phosphatase (AceK); Region: AceK; pfam06315
926550010381	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010382	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010383	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010384	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010385	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010386	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010387	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
926550010388	homodimer interface [polypeptide binding]; other site
926550010389	chemical substrate binding site [chemical binding]; other site
926550010390	oligomer interface [polypeptide binding]; other site
926550010391	metal binding site [ion binding]; metal-binding site
926550010392	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
926550010393	dimerization interface [polypeptide binding]; other site
926550010394	active site
926550010395	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
926550010396	RibD C-terminal domain; Region: RibD_C; cl17279
926550010397	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550010398	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550010399	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
926550010400	putative NAD(P) binding site [chemical binding]; other site
926550010401	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
926550010402	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550010403	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550010404	SMP-30/Gluconolaconase/LRE-like region; Region: SGL; pfam08450
926550010405	Strictosidine synthase; Region: Str_synth; pfam03088
926550010406	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
926550010407	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
926550010408	MoaE interaction surface [polypeptide binding]; other site
926550010409	MoeB interaction surface [polypeptide binding]; other site
926550010410	thiocarboxylated glycine; other site
926550010411	Domon-like ligand-binding domains; Region: DOMON_like; cl14783
926550010412	putative ligand binding site [chemical binding]; other site
926550010413	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926550010414	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550010415	catalytic residues [active]
926550010416	classical (c) SDRs; Region: SDR_c; cd05233
926550010417	NAD(P) binding site [chemical binding]; other site
926550010418	active site
926550010419	Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad...; Region: Tryp_SPc; cd00190
926550010420	cleavage site
926550010421	active site
926550010422	substrate binding sites [chemical binding]; other site
926550010423	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cl15674
926550010424	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
926550010425	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
926550010426	phenylhydantoinase; Validated; Region: PRK08323
926550010427	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
926550010428	tetramer interface [polypeptide binding]; other site
926550010429	active site
926550010430	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
926550010431	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
926550010432	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
926550010433	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
926550010434	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
926550010435	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
926550010436	transmembrane helices; other site
926550010437	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
926550010438	TrkA-C domain; Region: TrkA_C; pfam02080
926550010439	TrkA-C domain; Region: TrkA_C; pfam02080
926550010440	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
926550010441	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
926550010442	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
926550010443	active site
926550010444	nucleophile elbow; other site
926550010445	Predicted methyltransferases [General function prediction only]; Region: COG0313
926550010446	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
926550010447	putative SAM binding site [chemical binding]; other site
926550010448	putative homodimer interface [polypeptide binding]; other site
926550010449	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550010450	dolichyl-phosphate beta-D-mannosyltransferase; Region: PLN02726
926550010451	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926550010452	Ligand binding site; other site
926550010453	Putative Catalytic site; other site
926550010454	DXD motif; other site
926550010455	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
926550010456	AAA ATPase domain; Region: AAA_16; pfam13191
926550010457	AAA domain; Region: AAA_22; pfam13401
926550010458	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
926550010459	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550010460	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550010461	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
926550010462	6-phosphofructokinase, eukaryotic type; Region: 6PF1K_euk; TIGR02478
926550010463	active site
926550010464	ADP/pyrophosphate binding site [chemical binding]; other site
926550010465	dimerization interface [polypeptide binding]; other site
926550010466	allosteric effector site; other site
926550010467	fructose-1,6-bisphosphate binding site; other site
926550010468	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
926550010469	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
926550010470	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
926550010471	NAD(P) binding site [chemical binding]; other site
926550010472	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
926550010473	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases; Region: PFK; cl00204
926550010474	active site
926550010475	ADP/pyrophosphate binding site [chemical binding]; other site
926550010476	dimerization interface [polypeptide binding]; other site
926550010477	allosteric effector site; other site
926550010478	fructose-1,6-bisphosphate binding site; other site
926550010479	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
926550010480	active site
926550010481	zinc binding site [ion binding]; other site
926550010482	Na+ binding site [ion binding]; other site
926550010483	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550010484	substrate binding site [chemical binding]; other site
926550010485	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550010486	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550010487	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010488	dimer interface [polypeptide binding]; other site
926550010489	conserved gate region; other site
926550010490	putative PBP binding loops; other site
926550010491	ABC-ATPase subunit interface; other site
926550010492	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550010493	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010494	dimer interface [polypeptide binding]; other site
926550010495	conserved gate region; other site
926550010496	putative PBP binding loops; other site
926550010497	ABC-ATPase subunit interface; other site
926550010498	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550010499	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010500	Walker A/P-loop; other site
926550010501	ATP binding site [chemical binding]; other site
926550010502	Q-loop/lid; other site
926550010503	ABC transporter signature motif; other site
926550010504	Walker B; other site
926550010505	D-loop; other site
926550010506	H-loop/switch region; other site
926550010507	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550010508	Protein of unknown function (DUF2283); Region: DUF2283; pfam10049
926550010509	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550010510	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010511	Walker A/P-loop; other site
926550010512	ATP binding site [chemical binding]; other site
926550010513	Q-loop/lid; other site
926550010514	ABC transporter signature motif; other site
926550010515	Walker B; other site
926550010516	D-loop; other site
926550010517	H-loop/switch region; other site
926550010518	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550010519	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550010520	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010521	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550010522	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010523	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550010524	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010525	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010526	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550010527	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010528	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
926550010529	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010530	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
926550010531	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
926550010532	active site
926550010533	catalytic site [active]
926550010534	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
926550010535	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
926550010536	N-terminal catalytic domain of mainly uncharacterized eukaryotic proteins similar to alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_like_1; cd10791
926550010537	putative active site [active]
926550010538	catalytic site [active]
926550010539	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550010540	methionine sulfoxide reductase A; Provisional; Region: PRK14054
926550010541	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550010542	nucleotide binding site [chemical binding]; other site
926550010543	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
926550010544	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010545	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010546	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010547	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550010548	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010549	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010550	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010551	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010552	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010553	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010554	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550010555	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550010556	putative substrate translocation pore; other site
926550010557	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550010558	substrate binding site [chemical binding]; other site
926550010559	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550010560	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550010561	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010562	Walker A/P-loop; other site
926550010563	ATP binding site [chemical binding]; other site
926550010564	Q-loop/lid; other site
926550010565	ABC transporter signature motif; other site
926550010566	Walker B; other site
926550010567	D-loop; other site
926550010568	H-loop/switch region; other site
926550010569	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550010570	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550010571	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010572	Walker A/P-loop; other site
926550010573	ATP binding site [chemical binding]; other site
926550010574	Q-loop/lid; other site
926550010575	ABC transporter signature motif; other site
926550010576	Walker B; other site
926550010577	D-loop; other site
926550010578	H-loop/switch region; other site
926550010579	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550010580	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550010581	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
926550010582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010583	dimer interface [polypeptide binding]; other site
926550010584	conserved gate region; other site
926550010585	ABC-ATPase subunit interface; other site
926550010586	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550010587	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010588	dimer interface [polypeptide binding]; other site
926550010589	conserved gate region; other site
926550010590	putative PBP binding loops; other site
926550010591	ABC-ATPase subunit interface; other site
926550010592	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
926550010593	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
926550010594	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550010595	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
926550010596	N- and C-terminal domain interface [polypeptide binding]; other site
926550010597	active site
926550010598	MgATP binding site [chemical binding]; other site
926550010599	catalytic site [active]
926550010600	metal binding site [ion binding]; metal-binding site
926550010601	xylulose binding site [chemical binding]; other site
926550010602	homodimer interface [polypeptide binding]; other site
926550010603	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
926550010604	DNA polymerase alpha chain like domain; Region: POLIIIAc; smart00481
926550010605	active site
926550010606	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550010607	NAD(P) binding site [chemical binding]; other site
926550010608	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550010609	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550010610	NAD(P) binding site [chemical binding]; other site
926550010611	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
926550010612	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550010613	NAD(P) binding site [chemical binding]; other site
926550010614	active site
926550010615	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
926550010616	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926550010617	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550010618	putative DNA binding site [nucleotide binding]; other site
926550010619	putative Zn2+ binding site [ion binding]; other site
926550010620	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926550010621	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
926550010622	N- and C-terminal domain interface [polypeptide binding]; other site
926550010623	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
926550010624	active site
926550010625	putative catalytic site [active]
926550010626	metal binding site [ion binding]; metal-binding site
926550010627	ATP binding site [chemical binding]; other site
926550010628	carbohydrate binding site [chemical binding]; other site
926550010629	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
926550010630	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
926550010631	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550010632	ATP binding site [chemical binding]; other site
926550010633	putative Mg++ binding site [ion binding]; other site
926550010634	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550010635	nucleotide binding region [chemical binding]; other site
926550010636	ATP-binding site [chemical binding]; other site
926550010637	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
926550010638	NAD(P) binding site [chemical binding]; other site
926550010639	LDH/MDH dimer interface [polypeptide binding]; other site
926550010640	alpha-galactosidase; Provisional; Region: PRK15076
926550010641	substrate binding site [chemical binding]; other site
926550010642	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550010643	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010644	dimer interface [polypeptide binding]; other site
926550010645	conserved gate region; other site
926550010646	putative PBP binding loops; other site
926550010647	ABC-ATPase subunit interface; other site
926550010648	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010649	putative PBP binding loops; other site
926550010650	dimer interface [polypeptide binding]; other site
926550010651	ABC-ATPase subunit interface; other site
926550010652	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550010653	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550010654	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550010655	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
926550010656	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
926550010657	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
926550010658	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
926550010659	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
926550010660	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550010661	L-iditol 2-dehydrogenase; Region: iditol_2_DH_like; cd08235
926550010662	putative NAD(P) binding site [chemical binding]; other site
926550010663	catalytic Zn binding site [ion binding]; other site
926550010664	L-fucose isomerase and related proteins [Carbohydrate transport and metabolism]; Region: FucI; COG2407
926550010665	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cd00578
926550010666	hexamer (dimer of trimers) interface [polypeptide binding]; other site
926550010667	substrate binding site [chemical binding]; other site
926550010668	trimer interface [polypeptide binding]; other site
926550010669	Mn binding site [ion binding]; other site
926550010670	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550010671	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
926550010672	N- and C-terminal domain interface [polypeptide binding]; other site
926550010673	putative active site [active]
926550010674	MgATP binding site [chemical binding]; other site
926550010675	catalytic site [active]
926550010676	metal binding site [ion binding]; metal-binding site
926550010677	putative xylulose binding site [chemical binding]; other site
926550010678	putative homodimer interface [polypeptide binding]; other site
926550010679	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
926550010680	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550010681	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550010682	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550010683	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550010684	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010685	dimer interface [polypeptide binding]; other site
926550010686	conserved gate region; other site
926550010687	putative PBP binding loops; other site
926550010688	ABC-ATPase subunit interface; other site
926550010689	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550010690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010691	dimer interface [polypeptide binding]; other site
926550010692	conserved gate region; other site
926550010693	putative PBP binding loops; other site
926550010694	ABC-ATPase subunit interface; other site
926550010695	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
926550010696	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
926550010697	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
926550010698	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
926550010699	Putative collagen-binding domain of a collagenase; Region: Collagen_bind_2; pfam12904
926550010700	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
926550010701	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
926550010702	NAD(P) binding site [chemical binding]; other site
926550010703	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550010704	FGGY family of carbohydrate kinases; Region: FGGY; cd00366
926550010705	N- and C-terminal domain interface [polypeptide binding]; other site
926550010706	active site
926550010707	MgATP binding site [chemical binding]; other site
926550010708	catalytic site [active]
926550010709	metal binding site [ion binding]; metal-binding site
926550010710	carbohydrate binding site [chemical binding]; other site
926550010711	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550010712	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
926550010713	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550010714	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; pfam13231
926550010715	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
926550010716	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
926550010717	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
926550010718	delta-60 repeat domain; Region: delta_60_rpt; TIGR02608
926550010719	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
926550010720	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
926550010721	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
926550010722	metal binding site 2 [ion binding]; metal-binding site
926550010723	putative DNA binding helix; other site
926550010724	metal binding site 1 [ion binding]; metal-binding site
926550010725	dimer interface [polypeptide binding]; other site
926550010726	structural Zn2+ binding site [ion binding]; other site
926550010727	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
926550010728	N-terminal catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_1; cd00649
926550010729	dimer interface [polypeptide binding]; other site
926550010730	active site
926550010731	heme binding site [chemical binding]; other site
926550010732	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
926550010733	PPOX class probable F420-dependent enzyme; Region: Rv1155_F420; TIGR03618
926550010734	Predicted redox protein, regulator of disulfide bond formation [Posttranslational modification, protein turnover, chaperones]; Region: COG1765
926550010735	tropinone reductase; Provisional; Region: PRK09242
926550010736	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550010737	NAD(P) binding site [chemical binding]; other site
926550010738	active site
926550010739	Protein of unknown function (DUF2723); Region: DUF2723; pfam11028
926550010740	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
926550010741	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
926550010742	catalytic triad [active]
926550010743	DNA gyrase subunit A; Validated; Region: PRK05560
926550010744	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
926550010745	CAP-like domain; other site
926550010746	active site
926550010747	primary dimer interface [polypeptide binding]; other site
926550010748	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010749	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010750	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010751	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010752	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010753	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
926550010754	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
926550010755	Divergent AAA domain; Region: AAA_4; pfam04326
926550010756	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
926550010757	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
926550010758	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
926550010759	Catalytic site [active]
926550010760	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
926550010761	intersubunit interface [polypeptide binding]; other site
926550010762	active site
926550010763	catalytic residue [active]
926550010764	RNA polymerase sigma factor RpoE; Provisional; Region: PRK09652
926550010765	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
926550010766	Cohesin domain, interaction parter of dockerin; Region: cohesin_like; cd08546
926550010767	dockerin binding interface; other site
926550010768	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
926550010769	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
926550010770	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
926550010771	active site
926550010772	AhpC/TSA antioxidant enzyme; Region: AhpC-TSA_2; pfam13911
926550010773	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
926550010774	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
926550010775	catalytic loop [active]
926550010776	iron binding site [ion binding]; other site
926550010777	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
926550010778	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
926550010779	B12 binding site [chemical binding]; other site
926550010780	cobalt ligand [ion binding]; other site
926550010781	Protein of unknown function (DUF2568); Region: DUF2568; pfam10823
926550010782	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
926550010783	Trimethylamine methyltransferase (MTTB); Region: MTTB; cl15385
926550010784	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
926550010785	The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members...; Region: MopB_Acetylene-hydratase; cd02759
926550010786	putative [Fe4-S4] binding site [ion binding]; other site
926550010787	putative molybdopterin cofactor binding site [chemical binding]; other site
926550010788	The MopB_CT_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. This...; Region: MopB_CT_Acetylene-hydratase; cd02781
926550010789	putative molybdopterin cofactor binding site; other site
926550010790	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
926550010791	metal binding site 2 [ion binding]; metal-binding site
926550010792	putative DNA binding helix; other site
926550010793	metal binding site 1 [ion binding]; metal-binding site
926550010794	dimer interface [polypeptide binding]; other site
926550010795	structural Zn2+ binding site [ion binding]; other site
926550010796	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_17; cd08503
926550010797	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550010798	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550010799	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010800	dimer interface [polypeptide binding]; other site
926550010801	conserved gate region; other site
926550010802	putative PBP binding loops; other site
926550010803	ABC-ATPase subunit interface; other site
926550010804	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550010805	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010806	dimer interface [polypeptide binding]; other site
926550010807	conserved gate region; other site
926550010808	ABC-ATPase subunit interface; other site
926550010809	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550010810	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010811	Walker A/P-loop; other site
926550010812	ATP binding site [chemical binding]; other site
926550010813	Q-loop/lid; other site
926550010814	ABC transporter signature motif; other site
926550010815	Walker B; other site
926550010816	D-loop; other site
926550010817	H-loop/switch region; other site
926550010818	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550010819	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550010820	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550010821	Walker A/P-loop; other site
926550010822	ATP binding site [chemical binding]; other site
926550010823	Q-loop/lid; other site
926550010824	ABC transporter signature motif; other site
926550010825	Walker B; other site
926550010826	D-loop; other site
926550010827	H-loop/switch region; other site
926550010828	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550010829	potential frameshift: common BLAST hit: gi|169830389|ref|YP_001716371.1| P-type HAD superfamily ATPase
926550010830	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
926550010831	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
926550010832	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550010833	motif II; other site
926550010834	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
926550010835	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
926550010836	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
926550010837	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550010838	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
926550010839	O-Antigen ligase; Region: Wzy_C; cl04850
926550010840	O-Antigen ligase; Region: Wzy_C; pfam04932
926550010841	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
926550010842	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
926550010843	active site
926550010844	putative substrate binding pocket [chemical binding]; other site
926550010845	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
926550010846	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550010847	DNA-binding site [nucleotide binding]; DNA binding site
926550010848	UTRA domain; Region: UTRA; pfam07702
926550010849	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550010850	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550010851	ligand binding site [chemical binding]; other site
926550010852	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550010853	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550010854	NAD(P) binding site [chemical binding]; other site
926550010855	active site
926550010856	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550010857	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550010858	Walker A/P-loop; other site
926550010859	ATP binding site [chemical binding]; other site
926550010860	Q-loop/lid; other site
926550010861	ABC transporter signature motif; other site
926550010862	Walker B; other site
926550010863	D-loop; other site
926550010864	H-loop/switch region; other site
926550010865	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550010866	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550010867	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550010868	TM-ABC transporter signature motif; other site
926550010869	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550010870	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550010871	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550010872	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550010873	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
926550010874	N- and C-terminal domain interface [polypeptide binding]; other site
926550010875	putative active site [active]
926550010876	MgATP binding site [chemical binding]; other site
926550010877	catalytic site [active]
926550010878	metal binding site [ion binding]; metal-binding site
926550010879	putative xylulose binding site [chemical binding]; other site
926550010880	putative homodimer interface [polypeptide binding]; other site
926550010881	CRISPR/Cas system-associated protein Csc2; Region: Csc2_I-D; cl11869
926550010882	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cl17503
926550010883	DEAD-like helicases superfamily; Region: DEXDc; smart00487
926550010884	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550010885	ATP binding site [chemical binding]; other site
926550010886	putative Mg++ binding site [ion binding]; other site
926550010887	Helicase conserved C-terminal domain; Region: Helicase_C; pfam00271
926550010888	Predicted transcriptional regulator [Transcription]; Region: COG2378
926550010889	WYL domain; Region: WYL; pfam13280
926550010890	CRISPR/Cas system-associated protein Csx15; Region: Csx15_I-U; cd09766
926550010891	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
926550010892	putative active site [active]
926550010893	Protein of unknown function DUF86; Region: DUF86; pfam01934
926550010894	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550010895	active site
926550010896	NTP binding site [chemical binding]; other site
926550010897	metal binding triad [ion binding]; metal-binding site
926550010898	CRISPR/Cas system-associated protein Csm6; Region: Csm6_III-A; cl01634
926550010899	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cl10029
926550010900	CRISPR/Cas system-associated RAMP superfamily protein; Region: RAMP_I_III; cl17214
926550010901	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
926550010902	RNA binding site [nucleotide binding]; other site
926550010903	CRISPR/Cas system-associated protein Cmr5; Region: Cmr5_III-B; cd09749
926550010904	CRISPR system related protein, RAMP superfamily [Defense mechanisms]; Region: COG1336
926550010905	CRISPR-associated protein (Cas_Cmr3); Region: Cas_Cmr3; pfam09700
926550010906	CRISPR/Cas system-associated RAMP superfamily protein Cmr3; Region: Cmr3_III-B; cl12075
926550010907	CRISPR-associated protein Cas10/Cmr2, subtype III-B; Region: cas_TM1794_Cmr2; TIGR02577
926550010908	CRISPR-associated protein; Region: DUF3692; pfam12469
926550010909	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
926550010910	CRISPR/Cas system-associated protein Cas10; Region: Cas10_III; cl13853
926550010911	CRISPR/Cas system-associated RAMP superfamily protein Cmr1; Region: Cmr1_III-B; cl17436
926550010912	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3533
926550010913	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550010914	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010915	dimer interface [polypeptide binding]; other site
926550010916	conserved gate region; other site
926550010917	putative PBP binding loops; other site
926550010918	ABC-ATPase subunit interface; other site
926550010919	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550010920	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550010921	putative PBP binding loops; other site
926550010922	ABC-ATPase subunit interface; other site
926550010923	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550010924	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550010925	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550010926	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550010927	DNA binding site [nucleotide binding]
926550010928	domain linker motif; other site
926550010929	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550010930	dimerization interface [polypeptide binding]; other site
926550010931	ligand binding site [chemical binding]; other site
926550010932	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550010933	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_2; cd07805
926550010934	N- and C-terminal domain interface [polypeptide binding]; other site
926550010935	active site
926550010936	MgATP binding site [chemical binding]; other site
926550010937	catalytic site [active]
926550010938	metal binding site [ion binding]; metal-binding site
926550010939	xylulose binding site [chemical binding]; other site
926550010940	putative homodimer interface [polypeptide binding]; other site
926550010941	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550010942	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550010943	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550010944	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550010945	TM-ABC transporter signature motif; other site
926550010946	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550010947	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550010948	Walker A/P-loop; other site
926550010949	ATP binding site [chemical binding]; other site
926550010950	Q-loop/lid; other site
926550010951	ABC transporter signature motif; other site
926550010952	Walker B; other site
926550010953	D-loop; other site
926550010954	H-loop/switch region; other site
926550010955	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550010956	type I site-specific deoxyribonuclease, HsdR family; Region: hsdR; TIGR00348
926550010957	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550010958	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926550010959	active site residue [active]
926550010960	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550010961	Domain of unknown function DUF11; Region: DUF11; cl17728
926550010962	CARDB; Region: CARDB; pfam07705
926550010963	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
926550010964	CHAT domain; Region: CHAT; pfam12770
926550010965	Caspase domain; Region: Peptidase_C14; pfam00656
926550010966	Domain of unknown function (DUF4188); Region: DUF4188; pfam13826
926550010967	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550010968	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
926550010969	active site residue [active]
926550010970	SnoaL-like polyketide cyclase; Region: SnoaL; pfam07366
926550010971	Protein of unknown function (DUF1689); Region: DUF1689; pfam07954
926550010972	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550010973	S-adenosylmethionine binding site [chemical binding]; other site
926550010974	Predicted ATPase [General function prediction only]; Region: COG3903
926550010975	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550010976	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550010977	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926550010978	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926550010979	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550010980	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
926550010981	G4 box; other site
926550010982	G5 box; other site
926550010983	beta-Glucocerebrosidase 2 N terminal; Region: GBA2_N; pfam12215
926550010984	Predicted bile acid beta-glucosidase [Carbohydrate transport and metabolism]; Region: COG4354
926550010985	Protein of unknown function, DUF608; Region: DUF608; pfam04685
926550010986	BNR repeat-like domain; Region: BNR_2; pfam13088
926550010987	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
926550010988	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550010989	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550010990	N-terminal domain of Streptomyces griseus SgaA (suppression of growth disturbance caused by A-factor at a high concentration under high osmolality during early growth phase), and similar domains; Region: SgaA_N_like; cd07247
926550010991	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
926550010992	dimer interface [polypeptide binding]; other site
926550010993	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
926550010994	dimer interface [polypeptide binding]; other site
926550010995	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
926550010996	Prenyltransferase-like; Region: Prenyltrans_2; pfam13249
926550010997	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
926550010998	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
926550010999	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
926550011000	Walker A/P-loop; other site
926550011001	ATP binding site [chemical binding]; other site
926550011002	Q-loop/lid; other site
926550011003	ABC transporter signature motif; other site
926550011004	Walker B; other site
926550011005	D-loop; other site
926550011006	H-loop/switch region; other site
926550011007	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
926550011008	Walker A/P-loop; other site
926550011009	ATP binding site [chemical binding]; other site
926550011010	Q-loop/lid; other site
926550011011	ABC transporter signature motif; other site
926550011012	Walker B; other site
926550011013	D-loop; other site
926550011014	H-loop/switch region; other site
926550011015	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; pfam01923
926550011016	trehalose synthase, Pseudomonas stutzeri type; Region: TreS_stutzeri; TIGR02455
926550011017	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
926550011018	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550011019	Hydrogenase expression/synthesis hypA family; Region: HypA; cl17671
926550011020	CpXC protein; Region: CpXC; pfam14353
926550011021	competence damage-inducible protein A; Provisional; Region: PRK00549
926550011022	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
926550011023	putative MPT binding site; other site
926550011024	Competence-damaged protein; Region: CinA; cl00666
926550011025	HD domain; Region: HD_3; pfam13023
926550011026	Transcriptional regulator [Transcription]; Region: LytR; COG1316
926550011027	Transcriptional regulator [Transcription]; Region: LytR; COG1316
926550011028	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926550011029	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
926550011030	AP (apurinic/apyrimidinic) site pocket; other site
926550011031	DNA interaction; other site
926550011032	Metal-binding active site; metal-binding site
926550011033	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
926550011034	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
926550011035	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550011036	Predicted membrane protein [Function unknown]; Region: COG2246
926550011037	GtrA-like protein; Region: GtrA; pfam04138
926550011038	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
926550011039	O-Antigen ligase; Region: Wzy_C; pfam04932
926550011040	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
926550011041	Peptidase family M28; Region: Peptidase_M28; pfam04389
926550011042	metal binding site [ion binding]; metal-binding site
926550011043	Glycosyl hydrolase families 32 and 68, which for the clan GH-J; Region: GH_J; cd08979
926550011044	active site
926550011045	Deoxynucleoside kinases [Nucleotide transport and metabolism]; Region: COG1428
926550011046	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
926550011047	active site
926550011048	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
926550011049	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550011050	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550011051	homodimer interface [polypeptide binding]; other site
926550011052	catalytic residue [active]
926550011053	putative monovalent cation/H+ antiporter subunit G; Reviewed; Region: PRK12674
926550011054	Multisubunit Na+/H+ antiporter, MnhF subunit [Inorganic ion transport and metabolism]; Region: MnhF; COG2212
926550011055	putative monovalent cation/H+ antiporter subunit E; Reviewed; Region: PRK12651
926550011056	putative monovalent cation/H+ antiporter subunit D; Reviewed; Region: PRK12663
926550011057	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550011058	NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; Region: Oxidored_q2; cl00492
926550011059	putative monovalent cation/H+ antiporter subunit B; Reviewed; Region: PRK12509
926550011060	putative monovalent cation/H+ antiporter subunit A; Reviewed; Region: PRK12647
926550011061	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550011062	Multisubunit Na+/H+ antiporter, MnhB subunit [Inorganic ion transport and metabolism]; Region: MnhB; COG2111
926550011063	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
926550011064	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550011065	Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins [General function prediction only]; Region: PflX; COG1313
926550011066	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550011067	FeS/SAM binding site; other site
926550011068	BON domain; Region: BON; cl02771
926550011069	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
926550011070	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
926550011071	GDP-binding site [chemical binding]; other site
926550011072	ACT binding site; other site
926550011073	IMP binding site; other site
926550011074	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
926550011075	classical (c) SDRs; Region: SDR_c; cd05233
926550011076	NAD(P) binding site [chemical binding]; other site
926550011077	active site
926550011078	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
926550011079	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
926550011080	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
926550011081	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
926550011082	active site
926550011083	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
926550011084	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550011085	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550011086	homodimer interface [polypeptide binding]; other site
926550011087	catalytic residue [active]
926550011088	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
926550011089	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
926550011090	catalytic residues [active]
926550011091	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
926550011092	nudix motif; other site
926550011093	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
926550011094	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
926550011095	substrate binding site [chemical binding]; other site
926550011096	glutamase interaction surface [polypeptide binding]; other site
926550011097	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
926550011098	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
926550011099	metal binding site [ion binding]; metal-binding site
926550011100	NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding [DNA replication, recombination, and repair]; Region: NPY1; COG2816
926550011101	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
926550011102	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
926550011103	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
926550011104	putative NADH binding site [chemical binding]; other site
926550011105	putative active site [active]
926550011106	nudix motif; other site
926550011107	putative metal binding site [ion binding]; other site
926550011108	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
926550011109	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
926550011110	active site
926550011111	catalytic site [active]
926550011112	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550011113	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550011114	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550011115	chaperonin_like superfamily. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. There are 2 main chaperonin groups. The symmetry of type I...; Region: chaperonin_like; cl02777
926550011116	chaperonin GroL; Region: GroEL; TIGR02348
926550011117	PIN domain of ribonucleases (toxins), VapC, FitB, and PAE0151 of bacterial and archaeal toxin/antitoxin-like operons, and other similar homologs; Region: PIN_VapC-like; cd09861
926550011118	putative active site [active]
926550011119	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
926550011120	ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase; Region: ribokinase_pfkB_like; cl00192
926550011121	ATP binding site [chemical binding]; other site
926550011122	substrate binding site [chemical binding]; other site
926550011123	nuc_hydro_CeIAG: Nucleoside hydrolases similar to the inosine-adenosine-guanosine-preferring nucleoside hydrolase from Caenorhabditis elegans.  Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base; Region: nuc_hydro_CeIAG; cd02649
926550011124	active site
926550011125	Protein of unknown function DUF86; Region: DUF86; cl01031
926550011126	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550011127	active site
926550011128	NTP binding site [chemical binding]; other site
926550011129	metal binding triad [ion binding]; metal-binding site
926550011130	antibiotic binding site [chemical binding]; other site
926550011131	2-isopropylmalate synthase; Validated; Region: PRK00915
926550011132	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
926550011133	active site
926550011134	catalytic residues [active]
926550011135	metal binding site [ion binding]; metal-binding site
926550011136	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
926550011137	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
926550011138	domain interfaces; other site
926550011139	active site
926550011140	ketol-acid reductoisomerase; Provisional; Region: PRK05479
926550011141	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
926550011142	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
926550011143	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
926550011144	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
926550011145	putative valine binding site [chemical binding]; other site
926550011146	dimer interface [polypeptide binding]; other site
926550011147	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
926550011148	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
926550011149	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926550011150	PYR/PP interface [polypeptide binding]; other site
926550011151	dimer interface [polypeptide binding]; other site
926550011152	TPP binding site [chemical binding]; other site
926550011153	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926550011154	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
926550011155	TPP-binding site [chemical binding]; other site
926550011156	dimer interface [polypeptide binding]; other site
926550011157	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
926550011158	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
926550011159	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
926550011160	Protein of unknown function DUF58; Region: DUF58; pfam01882
926550011161	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
926550011162	FAD binding pocket [chemical binding]; other site
926550011163	conserved FAD binding motif [chemical binding]; other site
926550011164	phosphate binding motif [ion binding]; other site
926550011165	beta-alpha-beta structure motif; other site
926550011166	NAD binding pocket [chemical binding]; other site
926550011167	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
926550011168	marine proteobacterial sortase target protein; Region: marine_srt_targ; TIGR03788
926550011169	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
926550011170	metal ion-dependent adhesion site (MIDAS); other site
926550011171	polyphosphate kinase; Provisional; Region: PRK05443
926550011172	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
926550011173	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
926550011174	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
926550011175	putative domain interface [polypeptide binding]; other site
926550011176	putative active site [active]
926550011177	catalytic site [active]
926550011178	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
926550011179	putative domain interface [polypeptide binding]; other site
926550011180	putative active site [active]
926550011181	catalytic site [active]
926550011182	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550011183	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550011184	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550011185	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
926550011186	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550011187	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
926550011188	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011189	dimer interface [polypeptide binding]; other site
926550011190	conserved gate region; other site
926550011191	putative PBP binding loops; other site
926550011192	ABC-ATPase subunit interface; other site
926550011193	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550011194	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011195	putative PBP binding loops; other site
926550011196	dimer interface [polypeptide binding]; other site
926550011197	ABC-ATPase subunit interface; other site
926550011198	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926550011199	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550011200	Walker A/P-loop; other site
926550011201	ATP binding site [chemical binding]; other site
926550011202	Q-loop/lid; other site
926550011203	ABC transporter signature motif; other site
926550011204	Walker B; other site
926550011205	D-loop; other site
926550011206	H-loop/switch region; other site
926550011207	TOBE domain; Region: TOBE_2; pfam08402
926550011208	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
926550011209	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
926550011210	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
926550011211	DNA-binding site [nucleotide binding]; DNA binding site
926550011212	RNA-binding motif; other site
926550011213	Protein of unknown function DUF72; Region: DUF72; pfam01904
926550011214	ammonium transporter; Region: amt; TIGR00836
926550011215	2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Region: PhosphMutase; cl17294
926550011216	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550011217	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550011218	putative substrate translocation pore; other site
926550011219	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
926550011220	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
926550011221	aldehyde dehydrogenase family 7 member; Region: PLN02315
926550011222	NAD+-dependent alpha-aminoadipic semialdehyde dehydrogenase, ALDH family members 7A1 and 7B; Region: ALDH_F7_AASADH; cd07130
926550011223	tetrameric interface [polypeptide binding]; other site
926550011224	NAD binding site [chemical binding]; other site
926550011225	catalytic residues [active]
926550011226	Domain of unknown function DUF11; Region: DUF11; cl17728
926550011227	Domain of unknown function DUF11; Region: DUF11; cl17728
926550011228	Domain of unknown function DUF11; Region: DUF11; pfam01345
926550011229	Family description; Region: VCBS; pfam13517
926550011230	Family description; Region: VCBS; pfam13517
926550011231	Family description; Region: VCBS; pfam13517
926550011232	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cl11493
926550011233	active site
926550011234	Family description; Region: VCBS; pfam13517
926550011235	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550011236	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550011237	ligand binding site [chemical binding]; other site
926550011238	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
926550011239	dimerization interface [polypeptide binding]; other site
926550011240	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
926550011241	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550011242	dimer interface [polypeptide binding]; other site
926550011243	phosphorylation site [posttranslational modification]
926550011244	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550011245	ATP binding site [chemical binding]; other site
926550011246	Mg2+ binding site [ion binding]; other site
926550011247	G-X-G motif; other site
926550011248	Response regulator receiver domain; Region: Response_reg; pfam00072
926550011249	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550011250	active site
926550011251	phosphorylation site [posttranslational modification]
926550011252	intermolecular recognition site; other site
926550011253	dimerization interface [polypeptide binding]; other site
926550011254	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550011255	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550011256	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011257	ABC-ATPase subunit interface; other site
926550011258	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550011259	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550011260	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011261	dimer interface [polypeptide binding]; other site
926550011262	conserved gate region; other site
926550011263	putative PBP binding loops; other site
926550011264	ABC-ATPase subunit interface; other site
926550011265	PAP2, haloperoxidase_like subfamily. Haloperoxidases catalyze the oxidation of halides such as bromide or chloride by hydrogen peroxide, which results in subsequent halogenation of organic substrates, or halide-assisted disproportionation of hydrogen...; Region: PAP2_haloperoxidase; cd03398
926550011266	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
926550011267	active site
926550011268	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
926550011269	active site
926550011270	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550011271	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550011272	active site
926550011273	catalytic tetrad [active]
926550011274	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
926550011275	EamA-like transporter family; Region: EamA; pfam00892
926550011276	EamA-like transporter family; Region: EamA; pfam00892
926550011277	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
926550011278	metal binding triad [ion binding]; metal-binding site
926550011279	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
926550011280	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
926550011281	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
926550011282	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
926550011283	Domain of unknown function DUF21; Region: DUF21; pfam01595
926550011284	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926550011285	Transporter associated domain; Region: CorC_HlyC; smart01091
926550011286	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
926550011287	Domain of unknown function DUF21; Region: DUF21; pfam01595
926550011288	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
926550011289	Transporter associated domain; Region: CorC_HlyC; smart01091
926550011290	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
926550011291	non-specific DNA binding site [nucleotide binding]; other site
926550011292	salt bridge; other site
926550011293	sequence-specific DNA binding site [nucleotide binding]; other site
926550011294	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
926550011295	shikimate kinase; Reviewed; Region: aroK; PRK00131
926550011296	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
926550011297	MoaE homodimer interface [polypeptide binding]; other site
926550011298	MoaD interaction [polypeptide binding]; other site
926550011299	active site residues [active]
926550011300	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
926550011301	MoaE interaction surface [polypeptide binding]; other site
926550011302	MoeB interaction surface [polypeptide binding]; other site
926550011303	thiocarboxylated glycine; other site
926550011304	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
926550011305	trimer interface [polypeptide binding]; other site
926550011306	dimer interface [polypeptide binding]; other site
926550011307	putative active site [active]
926550011308	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
926550011309	active site
926550011310	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
926550011311	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
926550011312	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
926550011313	P loop; other site
926550011314	GTP binding site [chemical binding]; other site
926550011315	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550011316	Major Facilitator Superfamily; Region: MFS_1; pfam07690
926550011317	putative substrate translocation pore; other site
926550011318	peptide chain release factor 2; Validated; Region: prfB; PRK00578
926550011319	PCRF domain; Region: PCRF; pfam03462
926550011320	RF-1 domain; Region: RF-1; pfam00472
926550011321	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550011322	active site
926550011323	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550011324	catalytic tetrad [active]
926550011325	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550011326	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550011327	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
926550011328	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550011329	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
926550011330	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK07008
926550011331	Fatty acyl-CoA synthetases similar to LC-FACS from Thermus thermophiles; Region: ttLC_FACS_AlkK_like; cd12119
926550011332	dimer interface [polypeptide binding]; other site
926550011333	acyl-activating enzyme (AAE) consensus motif; other site
926550011334	putative active site [active]
926550011335	AMP binding site [chemical binding]; other site
926550011336	putative CoA binding site [chemical binding]; other site
926550011337	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550011338	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
926550011339	AP (apurinic/apyrimidinic) site pocket; other site
926550011340	DNA interaction; other site
926550011341	Metal-binding active site; metal-binding site
926550011342	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550011343	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550011344	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550011345	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
926550011346	AP endonuclease family 2 C terminus; Region: AP_endonuc_2_N; pfam07582
926550011347	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550011348	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550011349	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550011350	L-fucose isomerase (FucIase) and L-arabinose isomerase (AI) family; composed of FucIase, AI and similar proteins. FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose...; Region: L-fuc_L-ara-isomerases; cl00947
926550011351	hexamer (dimer of trimers) interface [polypeptide binding]; other site
926550011352	trimer interface [polypeptide binding]; other site
926550011353	substrate binding site [chemical binding]; other site
926550011354	Mn binding site [ion binding]; other site
926550011355	tyrosine decarboxylase MnfA; Region: tyr_de_CO2_Arch; TIGR03812
926550011356	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550011357	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550011358	catalytic residue [active]
926550011359	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550011360	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_2; cd07805
926550011361	N- and C-terminal domain interface [polypeptide binding]; other site
926550011362	active site
926550011363	MgATP binding site [chemical binding]; other site
926550011364	catalytic site [active]
926550011365	metal binding site [ion binding]; metal-binding site
926550011366	xylulose binding site [chemical binding]; other site
926550011367	putative homodimer interface [polypeptide binding]; other site
926550011368	Cation transport protein; Region: TrkH; cl17365
926550011369	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
926550011370	Sulfite oxidase (SO) family, molybdopterin binding domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). SO catalyzes the...; Region: SO_family_Moco; cd00321
926550011371	Moco binding site; other site
926550011372	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
926550011373	metal coordination site [ion binding]; other site
926550011374	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
926550011375	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
926550011376	G1 box; other site
926550011377	putative GEF interaction site [polypeptide binding]; other site
926550011378	GTP/Mg2+ binding site [chemical binding]; other site
926550011379	Switch I region; other site
926550011380	G2 box; other site
926550011381	G3 box; other site
926550011382	Switch II region; other site
926550011383	G4 box; other site
926550011384	G5 box; other site
926550011385	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
926550011386	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
926550011387	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
926550011388	TrkA-N domain; Region: TrkA_N; pfam02254
926550011389	TrkA-C domain; Region: TrkA_C; pfam02080
926550011390	TrkA-N domain; Region: TrkA_N; pfam02254
926550011391	TrkA-C domain; Region: TrkA_C; pfam02080
926550011392	Periplasmic binding protein; Region: Peripla_BP_6; pfam13458
926550011393	Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type I periplasmic binding fold protein superfamily; Region: PBP1_ABC_transporter_LIVBP_like; cd06268
926550011394	ligand binding site [chemical binding]; other site
926550011395	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
926550011396	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
926550011397	catalytic residue [active]
926550011398	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
926550011399	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
926550011400	tetramer interface [polypeptide binding]; other site
926550011401	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550011402	catalytic residue [active]
926550011403	multifunctional aminopeptidase A; Provisional; Region: PRK00913
926550011404	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
926550011405	interface (dimer of trimers) [polypeptide binding]; other site
926550011406	Substrate-binding/catalytic site; other site
926550011407	Zn-binding sites [ion binding]; other site
926550011408	aminotransferase; Validated; Region: PRK07777
926550011409	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550011410	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550011411	homodimer interface [polypeptide binding]; other site
926550011412	catalytic residue [active]
926550011413	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
926550011414	PhoU domain; Region: PhoU; pfam01895
926550011415	PhoU domain; Region: PhoU; pfam01895
926550011416	PrcB C-terminal; Region: PrcB_C; pfam14343
926550011417	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
926550011418	active site
926550011419	catalytic residues [active]
926550011420	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550011421	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550011422	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cd00306
926550011423	active site
926550011424	catalytic residues [active]
926550011425	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
926550011426	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
926550011427	HIGH motif; other site
926550011428	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
926550011429	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
926550011430	active site
926550011431	KMSKS motif; other site
926550011432	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
926550011433	tRNA binding surface [nucleotide binding]; other site
926550011434	anticodon binding site; other site
926550011435	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
926550011436	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
926550011437	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
926550011438	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
926550011439	Predicted sugar phosphatases of the HAD superfamily [Carbohydrate transport and metabolism]; Region: NagD; COG0647
926550011440	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550011441	active site
926550011442	motif I; other site
926550011443	motif II; other site
926550011444	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550011445	motif II; other site
926550011446	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
926550011447	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550011448	E3 interaction surface; other site
926550011449	lipoyl attachment site [posttranslational modification]; other site
926550011450	e3 binding domain; Region: E3_binding; pfam02817
926550011451	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550011452	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
926550011453	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550011454	tetramer interface [polypeptide binding]; other site
926550011455	TPP-binding site [chemical binding]; other site
926550011456	heterodimer interface [polypeptide binding]; other site
926550011457	phosphorylation loop region [posttranslational modification]
926550011458	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550011459	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
926550011460	PYR/PP interface [polypeptide binding]; other site
926550011461	dimer interface [polypeptide binding]; other site
926550011462	TPP binding site [chemical binding]; other site
926550011463	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550011464	Bacterial SH3 domain homologues; Region: SH3b; smart00287
926550011465	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550011466	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550011467	Acylphosphatase; Region: Acylphosphatase; pfam00708
926550011468	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
926550011469	Transcriptional regulator [Transcription]; Region: IclR; COG1414
926550011470	Bacterial transcriptional regulator; Region: IclR; pfam01614
926550011471	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cd00260
926550011472	catalytic site [active]
926550011473	BNR repeat-like domain; Region: BNR_2; pfam13088
926550011474	Asp-box motif; other site
926550011475	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
926550011476	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
926550011477	inhibitor site; inhibition site
926550011478	active site
926550011479	dimer interface [polypeptide binding]; other site
926550011480	catalytic residue [active]
926550011481	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550011482	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550011483	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550011484	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011485	ABC-ATPase subunit interface; other site
926550011486	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550011487	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011488	dimer interface [polypeptide binding]; other site
926550011489	conserved gate region; other site
926550011490	putative PBP binding loops; other site
926550011491	ABC-ATPase subunit interface; other site
926550011492	DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes [Carbohydrate transport and metabolism]; Region: FbaB; COG1830
926550011493	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
926550011494	putative active site; other site
926550011495	catalytic residue [active]
926550011496	Glycosyl hydrolase family 43; Region: GH43_ABN_1; cd08998
926550011497	substrate binding site [chemical binding]; other site
926550011498	active site
926550011499	hypothetical protein; Provisional; Region: PRK08609
926550011500	Nucleotidyltransferase (NT) domain of family X DNA Polymerases; Region: NT_POLXc; cd00141
926550011501	active site
926550011502	primer binding site [nucleotide binding]; other site
926550011503	NTP  binding site [chemical binding]; other site
926550011504	metal binding triad [ion binding]; metal-binding site
926550011505	Polymerase and Histidinol Phosphatase domain of bacterial polymerase X; Region: PHP_PolX; cd07436
926550011506	active site
926550011507	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
926550011508	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
926550011509	FMN binding site [chemical binding]; other site
926550011510	active site
926550011511	catalytic residues [active]
926550011512	substrate binding site [chemical binding]; other site
926550011513	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550011514	dimerization interface [polypeptide binding]; other site
926550011515	putative DNA binding site [nucleotide binding]; other site
926550011516	putative Zn2+ binding site [ion binding]; other site
926550011517	Low molecular weight phosphatase family; Region: LMWPc; cd00115
926550011518	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
926550011519	active site
926550011520	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
926550011521	Low molecular weight phosphatase family; Region: LMWPc; cd00115
926550011522	active site
926550011523	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550011524	PAS domain; Region: PAS_9; pfam13426
926550011525	putative active site [active]
926550011526	heme pocket [chemical binding]; other site
926550011527	PAS fold; Region: PAS_4; pfam08448
926550011528	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550011529	putative active site [active]
926550011530	heme pocket [chemical binding]; other site
926550011531	GAF domain; Region: GAF; pfam01590
926550011532	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550011533	dimer interface [polypeptide binding]; other site
926550011534	phosphorylation site [posttranslational modification]
926550011535	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550011536	ATP binding site [chemical binding]; other site
926550011537	Mg2+ binding site [ion binding]; other site
926550011538	G-X-G motif; other site
926550011539	Response regulator receiver domain; Region: Response_reg; pfam00072
926550011540	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550011541	active site
926550011542	phosphorylation site [posttranslational modification]
926550011543	intermolecular recognition site; other site
926550011544	dimerization interface [polypeptide binding]; other site
926550011545	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
926550011546	PAS domain S-box; Region: sensory_box; TIGR00229
926550011547	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
926550011548	putative active site [active]
926550011549	heme pocket [chemical binding]; other site
926550011550	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
926550011551	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
926550011552	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
926550011553	phosphorylation site [posttranslational modification]
926550011554	dimer interface [polypeptide binding]; other site
926550011555	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
926550011556	ATP binding site [chemical binding]; other site
926550011557	Mg2+ binding site [ion binding]; other site
926550011558	G-X-G motif; other site
926550011559	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
926550011560	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550011561	active site
926550011562	phosphorylation site [posttranslational modification]
926550011563	intermolecular recognition site; other site
926550011564	dimerization interface [polypeptide binding]; other site
926550011565	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550011566	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
926550011567	MoxR-like ATPases [General function prediction only]; Region: COG0714
926550011568	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550011569	Walker A motif; other site
926550011570	ATP binding site [chemical binding]; other site
926550011571	Walker B motif; other site
926550011572	arginine finger; other site
926550011573	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
926550011574	Protein of unknown function DUF58; Region: DUF58; pfam01882
926550011575	6-phosphofructokinase; Provisional; Region: PRK03202
926550011576	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
926550011577	active site
926550011578	ADP/pyrophosphate binding site [chemical binding]; other site
926550011579	dimerization interface [polypeptide binding]; other site
926550011580	allosteric effector site; other site
926550011581	fructose-1,6-bisphosphate binding site; other site
926550011582	Fumble; Region: Fumble; cl17357
926550011583	N-terminal Early set domain associated with the catalytic domain of isoamylase-like (also called glycogen 6-glucanohydrolase) proteins; Region: E_set_Isoamylase_like_N; cd07184
926550011584	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
926550011585	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
926550011586	HIGH motif; other site
926550011587	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
926550011588	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
926550011589	active site
926550011590	KMSKS motif; other site
926550011591	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
926550011592	tRNA binding surface [nucleotide binding]; other site
926550011593	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550011594	S-adenosylmethionine binding site [chemical binding]; other site
926550011595	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
926550011596	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
926550011597	active site
926550011598	metal binding site [ion binding]; metal-binding site
926550011599	hypothetical protein; Provisional; Region: PRK07233
926550011600	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
926550011601	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
926550011602	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
926550011603	metal-dependent hydrolase; Provisional; Region: PRK00685
926550011604	4Fe-4S binding domain; Region: Fer4; cl02805
926550011605	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
926550011606	Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Region: Complex1_30kDa; cl16917
926550011607	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
926550011608	NADH dehydrogenase subunit D; Validated; Region: PRK06075
926550011609	NADH dehydrogenase subunit B; Validated; Region: PRK06411
926550011610	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550011611	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550011612	DNA binding residues [nucleotide binding]
926550011613	dimerization interface [polypeptide binding]; other site
926550011614	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550011615	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550011616	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
926550011617	Walker A/P-loop; other site
926550011618	ATP binding site [chemical binding]; other site
926550011619	Q-loop/lid; other site
926550011620	ABC transporter signature motif; other site
926550011621	Walker B; other site
926550011622	D-loop; other site
926550011623	H-loop/switch region; other site
926550011624	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
926550011625	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
926550011626	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
926550011627	Walker A/P-loop; other site
926550011628	ATP binding site [chemical binding]; other site
926550011629	Q-loop/lid; other site
926550011630	ABC transporter signature motif; other site
926550011631	Walker B; other site
926550011632	D-loop; other site
926550011633	H-loop/switch region; other site
926550011634	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
926550011635	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
926550011636	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
926550011637	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550011638	ligand binding site [chemical binding]; other site
926550011639	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
926550011640	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550011641	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
926550011642	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550011643	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550011644	TM-ABC transporter signature motif; other site
926550011645	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550011646	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550011647	Walker A/P-loop; other site
926550011648	ATP binding site [chemical binding]; other site
926550011649	Q-loop/lid; other site
926550011650	ABC transporter signature motif; other site
926550011651	Walker B; other site
926550011652	D-loop; other site
926550011653	H-loop/switch region; other site
926550011654	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550011655	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
926550011656	tetramer interface [polypeptide binding]; other site
926550011657	TPP-binding site [chemical binding]; other site
926550011658	heterodimer interface [polypeptide binding]; other site
926550011659	phosphorylation loop region [posttranslational modification]
926550011660	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
926550011661	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
926550011662	PYR/PP interface [polypeptide binding]; other site
926550011663	dimer interface [polypeptide binding]; other site
926550011664	TPP binding site [chemical binding]; other site
926550011665	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
926550011666	glycyl-tRNA synthetase; Provisional; Region: PRK14908
926550011667	glycyl-tRNA synthetase subunit alpha; Validated; Region: glyQ; PRK09348
926550011668	motif 1; other site
926550011669	dimer interface [polypeptide binding]; other site
926550011670	active site
926550011671	motif 2; other site
926550011672	motif 3; other site
926550011673	anticodon binding site; other site
926550011674	tRNA binding surface [nucleotide binding]; other site
926550011675	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
926550011676	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_2; cd06160
926550011677	Peptidase family M50; Region: Peptidase_M50; pfam02163
926550011678	active site
926550011679	putative substrate binding region [chemical binding]; other site
926550011680	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
926550011681	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
926550011682	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
926550011683	FAD binding site [chemical binding]; other site
926550011684	Uncharacterized protein involved in tolerance to divalent cations [Inorganic ion transport and metabolism]; Region: CutA; COG1324
926550011685	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
926550011686	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
926550011687	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
926550011688	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
926550011689	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
926550011690	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
926550011691	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
926550011692	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
926550011693	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
926550011694	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
926550011695	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
926550011696	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
926550011697	Bacterial phospho-glucose isomerase C-terminal region; Region: bact-PGI_C; pfam10432
926550011698	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
926550011699	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
926550011700	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550011701	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550011702	Bacterial SH3 domain homologues; Region: SH3b; smart00287
926550011703	Bacterial SH3 domain; Region: SH3_3; cl17532
926550011704	Beta-galactosidase; Region: Glyco_hydro_42; pfam02449
926550011705	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
926550011706	Predicted amidohydrolase [General function prediction only]; Region: COG0388
926550011707	active site
926550011708	catalytic triad [active]
926550011709	dimer interface [polypeptide binding]; other site
926550011710	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550011711	H+ Antiporter protein; Region: 2A0121; TIGR00900
926550011712	putative substrate translocation pore; other site
926550011713	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
926550011714	MarR family; Region: MarR_2; pfam12802
926550011715	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
926550011716	active site
926550011717	Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase; Region: AAT; pfam03417
926550011718	Uncharacterized small membrane protein [Function unknown]; Region: COG2363
926550011719	Predicted permeases [General function prediction only]; Region: RarD; COG2962
926550011720	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550011721	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550011722	ligand binding site [chemical binding]; other site
926550011723	flexible hinge region; other site
926550011724	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926550011725	putative switch regulator; other site
926550011726	non-specific DNA interactions [nucleotide binding]; other site
926550011727	DNA binding site [nucleotide binding]
926550011728	sequence specific DNA binding site [nucleotide binding]; other site
926550011729	putative cAMP binding site [chemical binding]; other site
926550011730	Ferredoxin [Energy production and conversion]; Region: COG1146
926550011731	4Fe-4S binding domain; Region: Fer4; pfam00037
926550011732	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
926550011733	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550011734	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550011735	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550011736	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550011737	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011738	dimer interface [polypeptide binding]; other site
926550011739	conserved gate region; other site
926550011740	putative PBP binding loops; other site
926550011741	ABC-ATPase subunit interface; other site
926550011742	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
926550011743	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011744	putative PBP binding loops; other site
926550011745	ABC-ATPase subunit interface; other site
926550011746	MoxR-like ATPases [General function prediction only]; Region: COG0714
926550011747	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550011748	Walker A motif; other site
926550011749	ATP binding site [chemical binding]; other site
926550011750	Walker B motif; other site
926550011751	arginine finger; other site
926550011752	Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only]; Region: COG1721
926550011753	Protein of unknown function DUF58; Region: DUF58; pfam01882
926550011754	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cd02883
926550011755	nudix motif; other site
926550011756	Uncharacterized ACR, COG1430; Region: DUF192; pfam02643
926550011757	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
926550011758	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
926550011759	Type IV secretory pathway component VirB11, and related ATPases. The homohexamer, VirB11 is one of eleven Vir proteins, which are required for T-pilus biogenesis and virulence in the transfer of T-DNA from the Ti (tumor-inducing) plasmid of bacterial to...; Region: VirB11-like_ATPase; cd01130
926550011760	ATP binding site [chemical binding]; other site
926550011761	Walker A motif; other site
926550011762	hexamer interface [polypeptide binding]; other site
926550011763	Walker B motif; other site
926550011764	Tetratricopeptide repeat; Region: TPR_16; pfam13432
926550011765	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550011766	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550011767	Flp pilus assembly protein TadC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: TadC; COG2064
926550011768	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926550011769	Flp pilus assembly protein TadB [Intracellular trafficking and secretion]; Region: TadB; COG4965
926550011770	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
926550011771	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550011772	active site
926550011773	phosphorylation site [posttranslational modification]
926550011774	intermolecular recognition site; other site
926550011775	dimerization interface [polypeptide binding]; other site
926550011776	AAA domain; Region: AAA_31; pfam13614
926550011777	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550011778	Flp pilus assembly protein CpaB [Intracellular trafficking and secretion]; Region: CpaB; COG3745
926550011779	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
926550011780	TadE-like protein; Region: TadE; pfam07811
926550011781	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
926550011782	DHH family; Region: DHH; pfam01368
926550011783	DHHA1 domain; Region: DHHA1; pfam02272
926550011784	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550011785	S-adenosylmethionine binding site [chemical binding]; other site
926550011786	RNase_H superfamily; Region: RNase_H_2; pfam13482
926550011787	active site
926550011788	substrate binding site [chemical binding]; other site
926550011789	Putative sterol carrier protein [Lipid metabolism]; Region: COG3255
926550011790	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
926550011791	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
926550011792	active site
926550011793	NAD binding site [chemical binding]; other site
926550011794	metal binding site [ion binding]; metal-binding site
926550011795	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
926550011796	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
926550011797	generic binding surface II; other site
926550011798	ssDNA binding site; other site
926550011799	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550011800	ATP binding site [chemical binding]; other site
926550011801	putative Mg++ binding site [ion binding]; other site
926550011802	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550011803	nucleotide binding region [chemical binding]; other site
926550011804	ATP-binding site [chemical binding]; other site
926550011805	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
926550011806	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
926550011807	DAK2 domain; Region: Dak2; pfam02734
926550011808	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
926550011809	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550011810	FeS/SAM binding site; other site
926550011811	FtsH Extracellular; Region: FtsH_ext; pfam06480
926550011812	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
926550011813	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550011814	Walker A motif; other site
926550011815	ATP binding site [chemical binding]; other site
926550011816	Walker B motif; other site
926550011817	arginine finger; other site
926550011818	Peptidase family M41; Region: Peptidase_M41; pfam01434
926550011819	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
926550011820	Predicted archaeal methyltransferase [General function prediction only]; Region: COG2521
926550011821	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550011822	S-adenosylmethionine binding site [chemical binding]; other site
926550011823	Predicted membrane protein [Function unknown]; Region: COG1470
926550011824	NPCBM-associated, NEW3 domain of alpha-galactosidase; Region: NPCBM_assoc; pfam10633
926550011825	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
926550011826	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
926550011827	Walker A/P-loop; other site
926550011828	ATP binding site [chemical binding]; other site
926550011829	Q-loop/lid; other site
926550011830	ABC transporter signature motif; other site
926550011831	Walker B; other site
926550011832	D-loop; other site
926550011833	H-loop/switch region; other site
926550011834	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
926550011835	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
926550011836	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
926550011837	cobalamin synthase; Reviewed; Region: cobS; PRK00235
926550011838	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
926550011839	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550011840	nucleotide binding site [chemical binding]; other site
926550011841	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
926550011842	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
926550011843	active site
926550011844	dimer interface [polypeptide binding]; other site
926550011845	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
926550011846	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
926550011847	dimer interface [polypeptide binding]; other site
926550011848	active site
926550011849	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
926550011850	dimer interface [polypeptide binding]; other site
926550011851	active site
926550011852	DinB superfamily; Region: DinB_2; pfam12867
926550011853	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; cl08390
926550011854	Hydroxyneurosporene synthase (CrtC); Region: CrtC; pfam07143
926550011855	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550011856	Protein of unknown function (DUF3380); Region: DUF3380; pfam11860
926550011857	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
926550011858	Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which...; Region: ZnMc; cl00064
926550011859	active site
926550011860	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
926550011861	Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily; Region: CE4_u7; cd10931
926550011862	putative active site [active]
926550011863	REJ domain; Region: REJ; pfam02010
926550011864	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
926550011865	Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of...; Region: LamG; cd00110
926550011866	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550011867	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550011868	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
926550011869	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
926550011870	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cl00218
926550011871	glycosyl hydrolase family 16; Region: Glyco_hydrolase_16; cd00413
926550011872	active site
926550011873	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550011874	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550011875	Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: CaiC; COG0318
926550011876	Adenylate forming domain, Class I; Region: AFD_class_I; cd04433
926550011877	acyl-activating enzyme (AAE) consensus motif; other site
926550011878	active site
926550011879	AMP binding site [chemical binding]; other site
926550011880	CoA binding site [chemical binding]; other site
926550011881	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550011882	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
926550011883	classical (c) SDRs; Region: SDR_c; cd05233
926550011884	NAD(P) binding site [chemical binding]; other site
926550011885	active site
926550011886	hypothetical protein; Provisional; Region: PRK07233
926550011887	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550011888	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
926550011889	active site
926550011890	UDP-N-acetylglucosamine 2-epimerase; Region: Epimerase_2; pfam02350
926550011891	homodimer interface [polypeptide binding]; other site
926550011892	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
926550011893	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926550011894	Ligand binding site; other site
926550011895	Putative Catalytic site; other site
926550011896	DXD motif; other site
926550011897	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550011898	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550011899	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926550011900	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550011901	inhibitor-cofactor binding pocket; inhibition site
926550011902	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550011903	catalytic residue [active]
926550011904	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
926550011905	putative trimer interface [polypeptide binding]; other site
926550011906	putative active site [active]
926550011907	putative substrate binding site [chemical binding]; other site
926550011908	putative CoA binding site [chemical binding]; other site
926550011909	O-Antigen ligase; Region: Wzy_C; pfam04932
926550011910	hopanoid biosynthesis associated radical SAM protein HpnJ; Region: HpnJ; TIGR03471
926550011911	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
926550011912	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550011913	FeS/SAM binding site; other site
926550011914	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
926550011915	Ligand binding site; other site
926550011916	Putative Catalytic site; other site
926550011917	DXD motif; other site
926550011918	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
926550011919	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550011920	putative CoA binding site [chemical binding]; other site
926550011921	putative trimer interface [polypeptide binding]; other site
926550011922	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
926550011923	trimer interface [polypeptide binding]; other site
926550011924	active site
926550011925	substrate binding site [chemical binding]; other site
926550011926	CoA binding site [chemical binding]; other site
926550011927	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
926550011928	Low molecular weight phosphatase family; Region: LMWPc; cl00105
926550011929	Chain length determinant protein; Region: Wzz; cl15801
926550011930	capsular exopolysaccharide family; Region: eps_fam; TIGR01007
926550011931	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550011932	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
926550011933	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550011934	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
926550011935	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
926550011936	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550011937	active site
926550011938	motif I; other site
926550011939	motif II; other site
926550011940	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
926550011941	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
926550011942	dimer interface [polypeptide binding]; other site
926550011943	active site
926550011944	Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605
926550011945	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
926550011946	NTP_transferases catalyze the transfer of nucleotides onto phosphosugars; Region: NTP_transferase; cd04181
926550011947	active site
926550011948	Substrate binding site; other site
926550011949	Mg++ binding site; other site
926550011950	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
926550011951	Bacterial sugar transferase; Region: Bac_transf; pfam02397
926550011952	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
926550011953	30S subunit binding site; other site
926550011954	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cl00220
926550011955	catalytic triad [active]
926550011956	conserved cis-peptide bond; other site
926550011957	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
926550011958	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
926550011959	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
926550011960	Glycosyl hydrolase family 43; Region: GH43_ABN_2; cd08999
926550011961	putative substrate binding site [chemical binding]; other site
926550011962	active site
926550011963	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550011964	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011965	dimer interface [polypeptide binding]; other site
926550011966	conserved gate region; other site
926550011967	putative PBP binding loops; other site
926550011968	ABC-ATPase subunit interface; other site
926550011969	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011970	dimer interface [polypeptide binding]; other site
926550011971	conserved gate region; other site
926550011972	putative PBP binding loops; other site
926550011973	ABC-ATPase subunit interface; other site
926550011974	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550011975	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550011976	Predicted transcriptional regulator [Transcription]; Region: COG4189
926550011977	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550011978	dimerization interface [polypeptide binding]; other site
926550011979	putative DNA binding site [nucleotide binding]; other site
926550011980	putative Zn2+ binding site [ion binding]; other site
926550011981	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
926550011982	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
926550011983	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550011984	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011985	dimer interface [polypeptide binding]; other site
926550011986	conserved gate region; other site
926550011987	putative PBP binding loops; other site
926550011988	ABC-ATPase subunit interface; other site
926550011989	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550011990	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550011991	dimer interface [polypeptide binding]; other site
926550011992	conserved gate region; other site
926550011993	putative PBP binding loops; other site
926550011994	ABC-ATPase subunit interface; other site
926550011995	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550011996	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550011997	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550011998	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550011999	DNA binding site [nucleotide binding]
926550012000	domain linker motif; other site
926550012001	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550012002	dimerization interface [polypeptide binding]; other site
926550012003	ligand binding site [chemical binding]; other site
926550012004	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
926550012005	Alpha-L-arabinofuranosidase C-terminus; Region: Alpha-L-AF_C; pfam06964
926550012006	ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; Region: AppF; COG4608
926550012007	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550012008	Walker A/P-loop; other site
926550012009	ATP binding site [chemical binding]; other site
926550012010	Q-loop/lid; other site
926550012011	ABC transporter signature motif; other site
926550012012	Walker B; other site
926550012013	D-loop; other site
926550012014	H-loop/switch region; other site
926550012015	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
926550012016	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
926550012017	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
926550012018	Walker A/P-loop; other site
926550012019	ATP binding site [chemical binding]; other site
926550012020	Q-loop/lid; other site
926550012021	ABC transporter signature motif; other site
926550012022	Walker B; other site
926550012023	D-loop; other site
926550012024	H-loop/switch region; other site
926550012025	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
926550012026	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
926550012027	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012028	dimer interface [polypeptide binding]; other site
926550012029	conserved gate region; other site
926550012030	putative PBP binding loops; other site
926550012031	ABC-ATPase subunit interface; other site
926550012032	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
926550012033	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
926550012034	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012035	dimer interface [polypeptide binding]; other site
926550012036	conserved gate region; other site
926550012037	putative PBP binding loops; other site
926550012038	ABC-ATPase subunit interface; other site
926550012039	The substrate binding domain of a cellulose-binding protein from Thermotoga maritima contains the type 2 periplasmic binding fold; Region: PBP2_TmCBP_oligosaccharides_like; cd08509
926550012040	substrate binding site [chemical binding]; other site
926550012041	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
926550012042	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550012043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550012044	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550012045	dimerization interface [polypeptide binding]; other site
926550012046	ligand binding site [chemical binding]; other site
926550012047	Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism]; Region: SUL1; COG0659
926550012048	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
926550012049	Sulfate transporter family; Region: Sulfate_transp; pfam00916
926550012050	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
926550012051	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
926550012052	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
926550012053	metal-binding site [ion binding]
926550012054	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550012055	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550012056	motif II; other site
926550012057	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: PRK12333
926550012058	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
926550012059	homodimer interface [polypeptide binding]; other site
926550012060	metal binding site [ion binding]; metal-binding site
926550012061	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
926550012062	Putative transposase of IS4/5 family (DUF4096); Region: DUF4096; pfam13340
926550012063	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
926550012064	Transposase DDE domain; Region: DDE_Tnp_1_3; pfam13612
926550012065	Transposase DDE domain; Region: DDE_Tnp_1_2; pfam13586
926550012066	S-AdoMet dependent tetrapyrrole methylases; Region: TP_methylase; cl00304
926550012067	homodimer interface [polypeptide binding]; other site
926550012068	active site
926550012069	SAM binding site [chemical binding]; other site
926550012070	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
926550012071	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
926550012072	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012073	homodimer interface [polypeptide binding]; other site
926550012074	catalytic residue [active]
926550012075	Zinc-dependent metalloprotease; MMP_like sub-family 3. A group of bacterial and fungal metalloproteinase domains similar to matrix metalloproteinases and astacin; Region: ZnMc_MMP_like_3; cd04327
926550012076	active site
926550012077	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
926550012078	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012079	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012080	dimer interface [polypeptide binding]; other site
926550012081	conserved gate region; other site
926550012082	putative PBP binding loops; other site
926550012083	ABC-ATPase subunit interface; other site
926550012084	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550012085	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012086	dimer interface [polypeptide binding]; other site
926550012087	conserved gate region; other site
926550012088	putative PBP binding loops; other site
926550012089	ABC-ATPase subunit interface; other site
926550012090	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550012091	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012092	Protein of unknown function (DUF1343); Region: DUF1343; pfam07075
926550012093	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
926550012094	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550012095	DNA-binding site [nucleotide binding]; DNA binding site
926550012096	UTRA domain; Region: UTRA; pfam07702
926550012097	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550012098	dimerization interface [polypeptide binding]; other site
926550012099	putative DNA binding site [nucleotide binding]; other site
926550012100	putative Zn2+ binding site [ion binding]; other site
926550012101	indolepyruvate/phenylpyruvate decarboxylase, Azospirillum family; Region: indol_phenyl_DC; TIGR03394
926550012102	Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Region: TPP_PYR_PDC_IPDC_like; cd07038
926550012103	dimer interface [polypeptide binding]; other site
926550012104	PYR/PP interface [polypeptide binding]; other site
926550012105	TPP binding site [chemical binding]; other site
926550012106	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926550012107	Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of...; Region: TPP_PDC_IPDC; cd02005
926550012108	TPP-binding site [chemical binding]; other site
926550012109	dimer interface [polypeptide binding]; other site
926550012110	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550012111	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550012112	active site
926550012113	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926550012114	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926550012115	Protein of unknown function (DUF1006); Region: DUF1006; pfam06224
926550012116	YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function.  YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase.   Other enzymes with this fold include the peroxisomal...; Region: YdeM; cd03454
926550012117	putative active site [active]
926550012118	putative catalytic site [active]
926550012119	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
926550012120	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
926550012121	catalytic residue [active]
926550012122	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
926550012123	pyrroline-5-carboxylate reductase; Region: PLN02688
926550012124	YGGT family; Region: YGGT; pfam02325
926550012125	Minimal MMP-like domain found in Acidothermus cellulolyticus hypothetical protein ACEL2062 and similar protein; Region: MMP_ACEL2062; cd12952
926550012126	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926550012127	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550012128	Walker A/P-loop; other site
926550012129	ATP binding site [chemical binding]; other site
926550012130	Q-loop/lid; other site
926550012131	ABC transporter signature motif; other site
926550012132	Walker B; other site
926550012133	D-loop; other site
926550012134	H-loop/switch region; other site
926550012135	TOBE domain; Region: TOBE_2; pfam08402
926550012136	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
926550012137	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012138	dimer interface [polypeptide binding]; other site
926550012139	conserved gate region; other site
926550012140	putative PBP binding loops; other site
926550012141	ABC-ATPase subunit interface; other site
926550012142	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012143	dimer interface [polypeptide binding]; other site
926550012144	conserved gate region; other site
926550012145	putative PBP binding loops; other site
926550012146	ABC-ATPase subunit interface; other site
926550012147	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
926550012148	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550012149	FOG: CBS domain [General function prediction only]; Region: COG0517
926550012150	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in  the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms.  They produce...; Region: CBS_pair_ACT_assoc2; cd04585
926550012151	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550012152	Ligand Binding Site [chemical binding]; other site
926550012153	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550012154	Ligand Binding Site [chemical binding]; other site
926550012155	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
926550012156	Ligand Binding Site [chemical binding]; other site
926550012157	Dihydroorotate dehydrogenase (DHOD) like proteins. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD...; Region: DHOD_like; cd04739
926550012158	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK07565
926550012159	putative active site [active]
926550012160	putative FMN binding site [chemical binding]; other site
926550012161	putative substrate binding site [chemical binding]; other site
926550012162	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
926550012163	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
926550012164	dimer interface [polypeptide binding]; other site
926550012165	PYR/PP interface [polypeptide binding]; other site
926550012166	TPP binding site [chemical binding]; other site
926550012167	substrate binding site [chemical binding]; other site
926550012168	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
926550012169	Domain of unknown function; Region: EKR; pfam10371
926550012170	4Fe-4S binding domain; Region: Fer4_6; pfam12837
926550012171	4Fe-4S binding domain; Region: Fer4; pfam00037
926550012172	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
926550012173	TPP-binding site [chemical binding]; other site
926550012174	dimer interface [polypeptide binding]; other site
926550012175	FOG: CBS domain [General function prediction only]; Region: COG0517
926550012176	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in  the acetoin utilization proteins in bacteria. Acetoin is a product of fermentative metabolism in many prokaryotic and eukaryotic microorganisms.  They produce...; Region: CBS_pair_ACT_assoc2; cd04585
926550012177	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
926550012178	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550012179	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550012180	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
926550012181	putative substrate translocation pore; other site
926550012182	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
926550012183	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
926550012184	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550012185	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
926550012186	FtsX-like permease family; Region: FtsX; pfam02687
926550012187	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
926550012188	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550012189	FtsX-like permease family; Region: FtsX; pfam02687
926550012190	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550012191	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550012192	Walker A/P-loop; other site
926550012193	ATP binding site [chemical binding]; other site
926550012194	Q-loop/lid; other site
926550012195	ABC transporter signature motif; other site
926550012196	Walker B; other site
926550012197	D-loop; other site
926550012198	H-loop/switch region; other site
926550012199	HlyD family secretion protein; Region: HlyD_3; pfam13437
926550012200	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550012201	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926550012202	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550012203	S-adenosylmethionine binding site [chemical binding]; other site
926550012204	Aminoglycoside 3-N-acetyltransferase; Region: Antibiotic_NAT; pfam02522
926550012205	hypothetical protein; Provisional; Region: PRK05858
926550012206	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
926550012207	PYR/PP interface [polypeptide binding]; other site
926550012208	dimer interface [polypeptide binding]; other site
926550012209	TPP binding site [chemical binding]; other site
926550012210	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
926550012211	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
926550012212	TPP-binding site; other site
926550012213	dimer interface [polypeptide binding]; other site
926550012214	Protein of unknown function (DUF2905); Region: DUF2905; pfam11146
926550012215	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550012216	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550012217	active site
926550012218	catalytic tetrad [active]
926550012219	YciI-like protein; Reviewed; Region: PRK12866
926550012220	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
926550012221	malto-oligosyltrehalose trehalohydrolase; Region: trehalose_TreZ; TIGR02402
926550012222	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
926550012223	active site
926550012224	catalytic site [active]
926550012225	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
926550012226	isocitrate dehydrogenase; Validated; Region: PRK06451
926550012227	isocitrate dehydrogenase; Reviewed; Region: PRK07006
926550012228	short chain dehydrogenase; Provisional; Region: PRK07035
926550012229	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550012230	NAD(P) binding site [chemical binding]; other site
926550012231	active site
926550012232	Bacillus subtilis PhoD and related proteins, metallophosphatase domain; Region: MPP_PhoD; cd07389
926550012233	putative active site [active]
926550012234	putative metal binding site [ion binding]; other site
926550012235	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
926550012236	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
926550012237	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
926550012238	DNA binding residues [nucleotide binding]
926550012239	dimerization interface [polypeptide binding]; other site
926550012240	Galactose oxidase, central domain; Region: Kelch_3; pfam13415
926550012241	Galactose oxidase, central domain; Region: Kelch_3; cl02701
926550012242	Kelch domain; Region: Kelch; smart00612
926550012243	Galactose oxidase, central domain; Region: Kelch_3; cl02701
926550012244	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
926550012245	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
926550012246	HIGH motif; other site
926550012247	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
926550012248	active site
926550012249	KMSKS motif; other site
926550012250	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
926550012251	tRNA binding surface [nucleotide binding]; other site
926550012252	anticodon binding site; other site
926550012253	Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism]; Region: COG2133
926550012254	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550012255	DDE superfamily endonuclease; Region: DDE_3; pfam13358
926550012256	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012257	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012258	dimer interface [polypeptide binding]; other site
926550012259	conserved gate region; other site
926550012260	putative PBP binding loops; other site
926550012261	ABC-ATPase subunit interface; other site
926550012262	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
926550012263	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012264	dimer interface [polypeptide binding]; other site
926550012265	conserved gate region; other site
926550012266	putative PBP binding loops; other site
926550012267	ABC-ATPase subunit interface; other site
926550012268	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550012269	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012270	Lamin Tail Domain; Region: LTD; pfam00932
926550012271	Lamin Tail Domain; Region: LTD; pfam00932
926550012272	Lamin Tail Domain; Region: LTD; pfam00932
926550012273	Lamin Tail Domain; Region: LTD; pfam00932
926550012274	YhcR_OBF_like: A subfamily of OB-fold domains similar to the OB folds of Bacillus subtilis YhcR. YhcR is a sugar-nonspecific nuclease, which is active in the presence of Ca2+ and Mn2+. It cleaves RNA endonucleolytically, producing 3'-monophosphate...; Region: YhcR_OBF_like; cd04486
926550012275	generic binding surface I; other site
926550012276	generic binding surface II; other site
926550012277	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cl00080
926550012278	dimer interface [polypeptide binding]; other site
926550012279	phosphorylation site [posttranslational modification]
926550012280	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
926550012281	ATP binding site [chemical binding]; other site
926550012282	Mg2+ binding site [ion binding]; other site
926550012283	G-X-G motif; other site
926550012284	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
926550012285	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
926550012286	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
926550012287	putative catalytic site [active]
926550012288	putative metal binding site [ion binding]; other site
926550012289	putative phosphate binding site [ion binding]; other site
926550012290	recombination factor protein RarA/unknown domain fusion protein; Reviewed; Region: PRK13341
926550012291	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550012292	Walker A motif; other site
926550012293	ATP binding site [chemical binding]; other site
926550012294	Walker B motif; other site
926550012295	arginine finger; other site
926550012296	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
926550012297	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
926550012298	YceI-like domain; Region: YceI; pfam04264
926550012299	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
926550012300	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD2; cd08298
926550012301	putative NAD(P) binding site [chemical binding]; other site
926550012302	putative substrate binding site [chemical binding]; other site
926550012303	catalytic Zn binding site [ion binding]; other site
926550012304	structural Zn binding site [ion binding]; other site
926550012305	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
926550012306	Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG1233
926550012307	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
926550012308	AmmeMemoRadiSam system radical SAM enzyme; Region: AmmeMemoSam_rS; TIGR04337
926550012309	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550012310	FeS/SAM binding site; other site
926550012311	Memo (mediator of ErbB2-driven cell motility) is co-precipitated with the C terminus of ErbB2, a protein involved in cell motility; Region: MEMO_like; cd07361
926550012312	putative ligand binding pocket/active site [active]
926550012313	putative metal binding site [ion binding]; other site
926550012314	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550012315	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012316	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012317	dimer interface [polypeptide binding]; other site
926550012318	conserved gate region; other site
926550012319	putative PBP binding loops; other site
926550012320	ABC-ATPase subunit interface; other site
926550012321	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012322	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012323	dimer interface [polypeptide binding]; other site
926550012324	conserved gate region; other site
926550012325	putative PBP binding loops; other site
926550012326	ABC-ATPase subunit interface; other site
926550012327	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
926550012328	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550012329	NAD(P) binding site [chemical binding]; other site
926550012330	active site
926550012331	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
926550012332	UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; Region: UDPG_MGDP_dh_C; pfam03720
926550012333	AMP-binding domain protein; Validated; Region: PRK07529
926550012334	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550012335	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_like_4; cd05944
926550012336	acyl-activating enzyme (AAE) consensus motif; other site
926550012337	putative AMP binding site [chemical binding]; other site
926550012338	putative active site [active]
926550012339	putative CoA binding site [chemical binding]; other site
926550012340	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
926550012341	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
926550012342	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
926550012343	FtsX-like permease family; Region: FtsX; pfam02687
926550012344	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
926550012345	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
926550012346	Walker A/P-loop; other site
926550012347	ATP binding site [chemical binding]; other site
926550012348	Q-loop/lid; other site
926550012349	ABC transporter signature motif; other site
926550012350	Walker B; other site
926550012351	D-loop; other site
926550012352	H-loop/switch region; other site
926550012353	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550012354	Bacterial SH3 domain; Region: SH3_3; pfam08239
926550012355	Transglycosylase; Region: Transgly; pfam00912
926550012356	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
926550012357	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
926550012358	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550012359	Coenzyme A binding pocket [chemical binding]; other site
926550012360	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550012361	AAA ATPase domain; Region: AAA_16; pfam13191
926550012362	Walker A motif; other site
926550012363	ATP binding site [chemical binding]; other site
926550012364	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926550012365	structural tetrad; other site
926550012366	FOG: WD40 repeat [General function prediction only]; Region: COG2319
926550012367	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cd00200
926550012368	structural tetrad; other site
926550012369	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926550012370	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
926550012371	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550012372	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012373	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012374	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012375	dimer interface [polypeptide binding]; other site
926550012376	conserved gate region; other site
926550012377	putative PBP binding loops; other site
926550012378	ABC-ATPase subunit interface; other site
926550012379	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012380	dimer interface [polypeptide binding]; other site
926550012381	conserved gate region; other site
926550012382	ABC-ATPase subunit interface; other site
926550012383	NAD synthetase; Reviewed; Region: nadE; PRK02628
926550012384	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
926550012385	multimer interface [polypeptide binding]; other site
926550012386	active site
926550012387	catalytic triad [active]
926550012388	protein interface 1 [polypeptide binding]; other site
926550012389	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
926550012390	homodimer interface [polypeptide binding]; other site
926550012391	NAD binding pocket [chemical binding]; other site
926550012392	ATP binding pocket [chemical binding]; other site
926550012393	Mg binding site [ion binding]; other site
926550012394	active-site loop [active]
926550012395	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
926550012396	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550012397	Walker A/P-loop; other site
926550012398	ATP binding site [chemical binding]; other site
926550012399	Q-loop/lid; other site
926550012400	ABC transporter signature motif; other site
926550012401	Walker B; other site
926550012402	D-loop; other site
926550012403	H-loop/switch region; other site
926550012404	TOBE domain; Region: TOBE; pfam03459
926550012405	TOBE domain; Region: TOBE_2; pfam08402
926550012406	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012407	dimer interface [polypeptide binding]; other site
926550012408	conserved gate region; other site
926550012409	putative PBP binding loops; other site
926550012410	ABC-ATPase subunit interface; other site
926550012411	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
926550012412	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012413	dimer interface [polypeptide binding]; other site
926550012414	conserved gate region; other site
926550012415	putative PBP binding loops; other site
926550012416	ABC-ATPase subunit interface; other site
926550012417	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
926550012418	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550012419	Response regulator receiver domain; Region: Response_reg; pfam00072
926550012420	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550012421	active site
926550012422	phosphorylation site [posttranslational modification]
926550012423	intermolecular recognition site; other site
926550012424	dimerization interface [polypeptide binding]; other site
926550012425	Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Region: HemL; COG0001
926550012426	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550012427	inhibitor-cofactor binding pocket; inhibition site
926550012428	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012429	catalytic residue [active]
926550012430	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
926550012431	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
926550012432	putative DNA binding site [nucleotide binding]; other site
926550012433	putative Zn2+ binding site [ion binding]; other site
926550012434	AsnC family; Region: AsnC_trans_reg; pfam01037
926550012435	Protein involved in cellulose biosynthesis (CelD) [Cell envelope biogenesis, outer membrane]; Region: COG5653
926550012436	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
926550012437	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
926550012438	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550012439	FeS/SAM binding site; other site
926550012440	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
926550012441	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; pfam10105
926550012442	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
926550012443	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
926550012444	probable F420-dependent oxidoreductase, Rv2161c family; Region: F420_Rv2161c; TIGR03619
926550012445	Uncharacterized conserved protein [Function unknown]; Region: COG2135
926550012446	ATP phosphoribosyltransferase regulatory subunit; Provisional; Region: hisZ; PRK12292
926550012447	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
926550012448	motif 1; other site
926550012449	dimer interface [polypeptide binding]; other site
926550012450	active site
926550012451	motif 2; other site
926550012452	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
926550012453	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
926550012454	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
926550012455	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
926550012456	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
926550012457	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
926550012458	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
926550012459	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
926550012460	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
926550012461	Domain of unknown function (DUF4397); Region: DUF4397; pfam14344
926550012462	Bacterial transcriptional activator domain; Region: BTAD; smart01043
926550012463	Predicted ATPase [General function prediction only]; Region: COG3903
926550012464	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012465	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550012466	binding surface
926550012467	TPR motif; other site
926550012468	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550012469	binding surface
926550012470	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012471	TPR motif; other site
926550012472	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012473	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
926550012474	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
926550012475	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
926550012476	TrkA-N domain; Region: TrkA_N; pfam02254
926550012477	TrkA-C domain; Region: TrkA_C; pfam02080
926550012478	TrkA-C domain; Region: TrkA_C; pfam02080
926550012479	hypothetical protein; Provisional; Region: PRK04262
926550012480	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
926550012481	dimer interface [polypeptide binding]; other site
926550012482	active site
926550012483	Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR); Region: HMG-CoA_reductase_classII; cd00644
926550012484	homodimer interface [polypeptide binding]; other site
926550012485	catalytic residues [active]
926550012486	NAD binding site [chemical binding]; other site
926550012487	substrate binding pocket [chemical binding]; other site
926550012488	flexible flap; other site
926550012489	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
926550012490	RimM N-terminal domain; Region: RimM; pfam01782
926550012491	PRC-barrel domain; Region: PRC; pfam05239
926550012492	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
926550012493	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cl00098
926550012494	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
926550012495	signal recognition particle protein; Provisional; Region: PRK10867
926550012496	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
926550012497	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
926550012498	P loop; other site
926550012499	GTP binding site [chemical binding]; other site
926550012500	Signal peptide binding domain; Region: SRP_SPB; pfam02978
926550012501	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
926550012502	ubiquinone biosynthesis hydroxylase family protein; Provisional; Region: PRK07608; cl17314
926550012503	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
926550012504	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
926550012505	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
926550012506	active site
926550012507	catalytic tetrad [active]
926550012508	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
926550012509	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
926550012510	Walker A/P-loop; other site
926550012511	ATP binding site [chemical binding]; other site
926550012512	Q-loop/lid; other site
926550012513	ABC transporter signature motif; other site
926550012514	Walker B; other site
926550012515	D-loop; other site
926550012516	H-loop/switch region; other site
926550012517	TOBE domain; Region: TOBE_2; pfam08402
926550012518	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012519	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012520	dimer interface [polypeptide binding]; other site
926550012521	conserved gate region; other site
926550012522	putative PBP binding loops; other site
926550012523	ABC-ATPase subunit interface; other site
926550012524	ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism]; Region: UgpA; COG1175
926550012525	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012526	dimer interface [polypeptide binding]; other site
926550012527	conserved gate region; other site
926550012528	putative PBP binding loops; other site
926550012529	ABC-ATPase subunit interface; other site
926550012530	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
926550012531	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012532	Transcriptional regulators [Transcription]; Region: PurR; COG1609
926550012533	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
926550012534	DNA binding site [nucleotide binding]
926550012535	domain linker motif; other site
926550012536	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
926550012537	ligand binding site [chemical binding]; other site
926550012538	dimerization interface [polypeptide binding]; other site
926550012539	Trimethylamine methyltransferase (MTTB); Region: MTTB; cl15385
926550012540	RNA polymerase sigma-70 factor, TIGR02952 family; Region: Sig70_famx2
926550012541	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550012542	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
926550012543	daunorubicin resistance ABC transporter ATP-binding subunit; Region: drrA; TIGR01188
926550012544	Walker A/P-loop; other site
926550012545	ATP binding site [chemical binding]; other site
926550012546	Q-loop/lid; other site
926550012547	ABC transporter signature motif; other site
926550012548	Walker B; other site
926550012549	D-loop; other site
926550012550	H-loop/switch region; other site
926550012551	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
926550012552	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
926550012553	active site
926550012554	dimer interface [polypeptide binding]; other site
926550012555	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
926550012556	dimer interface [polypeptide binding]; other site
926550012557	active site
926550012558	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550012559	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550012560	S-adenosylmethionine binding site [chemical binding]; other site
926550012561	Alpha amylase catalytic domain found in Amylosucrase; Region: AmyAc_Amylosucrase; cd11324
926550012562	trehalose synthase; Region: treS_nterm; TIGR02456
926550012563	active site
926550012564	catalytic site [active]
926550012565	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
926550012566	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08665
926550012567	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
926550012568	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
926550012569	active site
926550012570	dimer interface [polypeptide binding]; other site
926550012571	effector binding site; other site
926550012572	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
926550012573	TSCPD domain; Region: TSCPD; pfam12637
926550012574	transcriptional regulator NrdR; Region: TIGR00244
926550012575	ATP cone domain; Region: ATP-cone; pfam03477
926550012576	cell division protein FtsZ; Validated; Region: PRK09330
926550012577	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
926550012578	nucleotide binding site [chemical binding]; other site
926550012579	SulA interaction site; other site
926550012580	cell division protein FtsA; Region: ftsA; TIGR01174
926550012581	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
926550012582	nucleotide binding site [chemical binding]; other site
926550012583	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
926550012584	Cell division protein FtsA; Region: FtsA; pfam14450
926550012585	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
926550012586	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
926550012587	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
926550012588	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
926550012589	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
926550012590	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
926550012591	FAD binding domain; Region: FAD_binding_4; pfam01565
926550012592	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
926550012593	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
926550012594	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926550012595	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926550012596	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926550012597	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
926550012598	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
926550012599	homodimer interface [polypeptide binding]; other site
926550012600	active site
926550012601	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
926550012602	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
926550012603	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926550012604	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926550012605	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
926550012606	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
926550012607	Mg++ binding site [ion binding]; other site
926550012608	putative catalytic motif [active]
926550012609	putative substrate binding site [chemical binding]; other site
926550012610	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
926550012611	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
926550012612	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
926550012613	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
926550012614	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
926550012615	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
926550012616	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
926550012617	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
926550012618	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550012619	S-adenosylmethionine binding site [chemical binding]; other site
926550012620	cell division protein MraZ; Reviewed; Region: PRK00326
926550012621	MraZ protein; Region: MraZ; pfam02381
926550012622	MraZ protein; Region: MraZ; pfam02381
926550012623	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; pfam04563
926550012624	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
926550012625	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
926550012626	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
926550012627	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
926550012628	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
926550012629	RPB10 interaction site [polypeptide binding]; other site
926550012630	RPB11 interaction site [polypeptide binding]; other site
926550012631	RPB3 interaction site [polypeptide binding]; other site
926550012632	RPB12 interaction site [polypeptide binding]; other site
926550012633	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
926550012634	RPB1 interaction site [polypeptide binding]; other site
926550012635	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
926550012636	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
926550012637	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
926550012638	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
926550012639	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
926550012640	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
926550012641	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
926550012642	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
926550012643	DNA binding site [nucleotide binding]
926550012644	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
926550012645	putative acetyltransferase; Provisional; Region: PRK03624
926550012646	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550012647	Coenzyme A binding pocket [chemical binding]; other site
926550012648	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550012649	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
926550012650	Coenzyme A binding pocket [chemical binding]; other site
926550012651	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
926550012652	active site
926550012653	metal binding site [ion binding]; metal-binding site
926550012654	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
926550012655	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
926550012656	tetramer interface [polypeptide binding]; other site
926550012657	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012658	catalytic residue [active]
926550012659	3-methylcrotonyl-CoA carboxylase, beta chain; Region: PLN02820
926550012660	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
926550012661	Acetyl-CoA carboxylase alpha subunit [Lipid metabolism]; Region: AccA; cl17345
926550012662	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
926550012663	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
926550012664	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
926550012665	AAA domain; Region: AAA_30; pfam13604
926550012666	Family description; Region: UvrD_C_2; pfam13538
926550012667	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
926550012668	Cytochrome c; Region: Cytochrom_C; pfam00034
926550012669	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
926550012670	MoaE interaction surface [polypeptide binding]; other site
926550012671	MoeB interaction surface [polypeptide binding]; other site
926550012672	thiocarboxylated glycine; other site
926550012673	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
926550012674	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550012675	active site
926550012676	mercuric reductase; Validated; Region: PRK06370
926550012677	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550012678	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926550012679	Domain of unknown function DUF87; Region: DUF87; pfam01935
926550012680	AAA-like domain; Region: AAA_10; pfam12846
926550012681	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550012682	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012683	dimer interface [polypeptide binding]; other site
926550012684	conserved gate region; other site
926550012685	putative PBP binding loops; other site
926550012686	ABC-ATPase subunit interface; other site
926550012687	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
926550012688	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550012689	dimer interface [polypeptide binding]; other site
926550012690	conserved gate region; other site
926550012691	putative PBP binding loops; other site
926550012692	ABC-ATPase subunit interface; other site
926550012693	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550012694	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550012695	REG-2-like, HAD superfamily (subfamily IA) hydrolase; Region: DREG-2; TIGR02252
926550012696	Haloacid dehalogenase-like hydrolase; Region: HAD_2; pfam13419
926550012697	This family is most closely related to the GT1 family of glycosyltransferases. The sucrose-phosphate synthases in this family may be unique to plants and photosynthetic bacteria. This enzyme catalyzes the synthesis of sucrose 6-phosphate from fructose...; Region: GT1_Sucrose_synthase; cd03800
926550012698	D-inositol-3-phosphate glycosyltransferase; Region: mycothiol_MshA; TIGR03449
926550012699	putative ADP-binding pocket [chemical binding]; other site
926550012700	GlcNAc-PI de-N-acetylase; Region: PIG-L; cl00929
926550012701	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
926550012702	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
926550012703	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
926550012704	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
926550012705	SecA preprotein cross-linking domain; Region: SecA_PP_bind; pfam01043
926550012706	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cl17351
926550012707	nucleotide binding region [chemical binding]; other site
926550012708	SEC-C motif; Region: SEC-C; pfam02810
926550012709	Luciferase-like monooxygenase; Region: Bac_luciferase; pfam00296
926550012710	Flavin-utilizing monoxygenases; Region: Flavin_utilizing_monoxygenases; cl07892
926550012711	N5,N10-methylenetetrahydromethanopterin reductase (Mer) catalyzes the reduction of N5,N10-methylenetetrahydromethanopterin with reduced coenzyme F420 to N5-methyltetrahydromethanopterin and oxidized coenzyme F420; Region: Tetrahydromethanopterin_reductase; cd01097
926550012712	Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Region: TPP_enzyme_PYR; cl11410
926550012713	dimer interface [polypeptide binding]; other site
926550012714	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
926550012715	TPP-binding site [chemical binding]; other site
926550012716	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
926550012717	Uncharacterized conserved protein [Function unknown]; Region: COG4715
926550012718	SWIM zinc finger; Region: SWIM; pfam04434
926550012719	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550012720	active site
926550012721	NTP binding site [chemical binding]; other site
926550012722	metal binding triad [ion binding]; metal-binding site
926550012723	antibiotic binding site [chemical binding]; other site
926550012724	HEPN domain; Region: HEPN; pfam05168
926550012725	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550012726	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
926550012727	peptide binding site [polypeptide binding]; other site
926550012728	dimer interface [polypeptide binding]; other site
926550012729	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
926550012730	short chain dehydrogenase; Provisional; Region: PRK06197
926550012731	retinol dehydrogenase (retinol-DH), Light dependent Protochlorophyllide (Pchlide) OxidoReductase (LPOR) and related proteins, classical (c) SDRs; Region: retinol-DH_like_SDR_c_like; cd05327
926550012732	putative NAD(P) binding site [chemical binding]; other site
926550012733	active site
926550012734	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK14481
926550012735	Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Region: DAK1; COG2376
926550012736	DAK2 domain; Region: Dak2; pfam02734
926550012737	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
926550012738	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
926550012739	ligand binding site [chemical binding]; other site
926550012740	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550012741	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550012742	Walker A/P-loop; other site
926550012743	ATP binding site [chemical binding]; other site
926550012744	Q-loop/lid; other site
926550012745	ABC transporter signature motif; other site
926550012746	Walker B; other site
926550012747	D-loop; other site
926550012748	H-loop/switch region; other site
926550012749	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550012750	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550012751	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550012752	TM-ABC transporter signature motif; other site
926550012753	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550012754	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550012755	TM-ABC transporter signature motif; other site
926550012756	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
926550012757	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
926550012758	Septum formation initiator; Region: DivIC; cl17659
926550012759	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
926550012760	substrate binding site [chemical binding]; other site
926550012761	activation loop (A-loop); other site
926550012762	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
926550012763	Clp amino terminal domain; Region: Clp_N; pfam02861
926550012764	Clp amino terminal domain; Region: Clp_N; pfam02861
926550012765	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550012766	Walker A motif; other site
926550012767	ATP binding site [chemical binding]; other site
926550012768	Walker B motif; other site
926550012769	arginine finger; other site
926550012770	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550012771	Walker A motif; other site
926550012772	ATP binding site [chemical binding]; other site
926550012773	Walker B motif; other site
926550012774	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
926550012775	Uncharacterized protein family UPF0027; Region: UPF0027; pfam01139
926550012776	hypothetical protein; Reviewed; Region: PRK09588
926550012777	Archease protein family (MTH1598/TM1083); Region: Archease; pfam01951
926550012778	Endo-N-acetylmuramidases (muramidases) are lysozymes (also referred to as peptidoglycan hydrolases) that degrade bacterial cell walls by catalyzing the hydrolysis of 1,4-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues; Region: GH25_muramidase; cl10448
926550012779	active site
926550012780	Salmonella virulence plasmid 65kDa B protein; Region: SpvB; pfam03534
926550012781	RHS Repeat; Region: RHS_repeat; pfam05593
926550012782	RHS Repeat; Region: RHS_repeat; cl11982
926550012783	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
926550012784	RHS Repeat; Region: RHS_repeat; pfam05593
926550012785	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550012786	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
926550012787	active site
926550012788	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550012789	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
926550012790	KTSC domain; Region: KTSC; pfam13619
926550012791	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550012792	ATP binding site [chemical binding]; other site
926550012793	putative Mg++ binding site [ion binding]; other site
926550012794	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
926550012795	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
926550012796	nucleotide binding region [chemical binding]; other site
926550012797	ATP-binding site [chemical binding]; other site
926550012798	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
926550012799	four helix bundle protein; Region: TIGR02436
926550012800	S23 ribosomal protein; Region: Ribosomal_S23p; cl05287
926550012801	Methyltransferase domain; Region: Methyltransf_26; pfam13659
926550012802	Uncharacterized protein conserved in bacteria (DUF2191); Region: DUF2191; pfam09957
926550012803	PIN domain of the Rv0301 toxin of Mycobacterium tuberculosis and other uncharacterized, annotated PilT protein domain proteins; Region: PIN_MtRv0301; cd09882
926550012804	putative active site [active]
926550012805	Domain of unknown function (DUF4095); Region: DUF4095; pfam13338
926550012806	Nucleotidyl transferase of unknown function (DUF1814); Region: DUF1814; pfam08843
926550012807	Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster [General function prediction only]; Region: COG1205
926550012808	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
926550012809	ATP binding site [chemical binding]; other site
926550012810	putative Mg++ binding site [ion binding]; other site
926550012811	Domain of unknown function (DUF1998); Region: DUF1998; pfam09369
926550012812	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
926550012813	Uncharacterized conserved protein [Function unknown]; Region: COG3375
926550012814	malate dehydrogenase; Provisional; Region: PRK05442
926550012815	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
926550012816	NAD(P) binding site [chemical binding]; other site
926550012817	dimer interface [polypeptide binding]; other site
926550012818	malate binding site [chemical binding]; other site
926550012819	sucrose phosphate synthase/possible sucrose phosphate phosphatase, plant; Region: sucrsPsyn_pln; TIGR02468
926550012820	Family description; Region: VCBS; pfam13517
926550012821	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
926550012822	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
926550012823	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
926550012824	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
926550012825	DNA binding residues [nucleotide binding]
926550012826	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
926550012827	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
926550012828	CoA-transferase family III; Region: CoA_transf_3; pfam02515
926550012829	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
926550012830	cyclase homology domain; Region: CHD; cd07302
926550012831	nucleotidyl binding site; other site
926550012832	metal binding site [ion binding]; metal-binding site
926550012833	dimer interface [polypeptide binding]; other site
926550012834	cyclase homology domain; Region: CHD; cd07302
926550012835	nucleotidyl binding site; other site
926550012836	dimer interface [polypeptide binding]; other site
926550012837	metal binding site [ion binding]; metal-binding site
926550012838	Adenylate cyclase, family 3 (some proteins contain HAMP domain) [Signal transduction mechanisms]; Region: CyaA; COG2114
926550012839	AAA ATPase domain; Region: AAA_16; pfam13191
926550012840	Predicted ATPase [General function prediction only]; Region: COG3899
926550012841	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012842	Tetratricopeptide repeats; Region: TPR; smart00028
926550012843	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012844	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
926550012845	binding surface
926550012846	TPR motif; other site
926550012847	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012848	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012849	Tetratricopeptide repeat; Region: TPR_12; pfam13424
926550012850	Protein of unknown function (DUF1800); Region: DUF1800; pfam08811
926550012851	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4102
926550012852	glycine dehydrogenase; Provisional; Region: PRK05367
926550012853	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
926550012854	tetramer interface [polypeptide binding]; other site
926550012855	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012856	catalytic residue [active]
926550012857	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
926550012858	tetramer interface [polypeptide binding]; other site
926550012859	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012860	catalytic residue [active]
926550012861	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
926550012862	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550012863	PIN domain of the Pyrobaculum aerophilum Pae0151 and Pae2754 proteins and homologs; Region: PIN_Pae0151; cd09873
926550012864	homotetrameric interface [polypeptide binding]; other site
926550012865	putative active site [active]
926550012866	metal binding site [ion binding]; metal-binding site
926550012867	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550012868	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550012869	active site
926550012870	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
926550012871	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
926550012872	active site
926550012873	Alpha-L-rhamnosidase N-terminal domain; Region: Bac_rhamnosid_N; pfam08531
926550012874	Bacterial alpha-L-rhamnosidase; Region: Bac_rhamnosid; pfam05592
926550012875	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550012876	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
926550012877	putative ADP-binding pocket [chemical binding]; other site
926550012878	Capsular polysaccharide biosynthesis protein [Cell envelope biogenesis, outer membrane]; Region: COG3944
926550012879	Chain length determinant protein; Region: Wzz; pfam02706
926550012880	Scaffold protein Nfu/NifU N terminal; Region: Nfu_N; cl07364
926550012881	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
926550012882	active site
926550012883	dimer interface [polypeptide binding]; other site
926550012884	catalytic nucleophile [active]
926550012885	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
926550012886	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
926550012887	E3 interaction surface; other site
926550012888	lipoyl attachment site [posttranslational modification]; other site
926550012889	e3 binding domain; Region: E3_binding; pfam02817
926550012890	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
926550012891	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK07818
926550012892	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
926550012893	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
926550012894	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
926550012895	active site
926550012896	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550012897	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550012898	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550012899	NAD(P) binding site [chemical binding]; other site
926550012900	active site
926550012901	YceG-like family; Region: YceG; pfam02618
926550012902	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
926550012903	dimerization interface [polypeptide binding]; other site
926550012904	Thioredoxin; Region: Thioredoxin_4; pfam13462
926550012905	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
926550012906	Thioredoxin; Region: Thioredoxin_4; pfam13462
926550012907	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
926550012908	Winged helix-turn helix; Region: HTH_29; pfam13551
926550012909	Homeodomain-like domain; Region: HTH_23; pfam13384
926550012910	Homeodomain-like domain; Region: HTH_32; pfam13565
926550012911	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
926550012912	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
926550012913	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
926550012914	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
926550012915	Beta-lactamase superfamily domain; Region: Lactamase_B_3; pfam13483
926550012916	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
926550012917	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
926550012918	active site
926550012919	dimerization interface [polypeptide binding]; other site
926550012920	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
926550012921	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
926550012922	ligand binding site [chemical binding]; other site
926550012923	flexible hinge region; other site
926550012924	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
926550012925	putative switch regulator; other site
926550012926	non-specific DNA interactions [nucleotide binding]; other site
926550012927	DNA binding site [nucleotide binding]
926550012928	sequence specific DNA binding site [nucleotide binding]; other site
926550012929	putative cAMP binding site [chemical binding]; other site
926550012930	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
926550012931	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
926550012932	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550012933	catalytic residues [active]
926550012934	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
926550012935	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
926550012936	This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible...; Region: PGM_like2; cd05800
926550012937	active site
926550012938	substrate binding site [chemical binding]; other site
926550012939	metal binding site [ion binding]; metal-binding site
926550012940	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
926550012941	active site
926550012942	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
926550012943	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
926550012944	substrate binding pocket [chemical binding]; other site
926550012945	chain length determination region; other site
926550012946	substrate-Mg2+ binding site; other site
926550012947	catalytic residues [active]
926550012948	aspartate-rich region 1; other site
926550012949	active site lid residues [active]
926550012950	aspartate-rich region 2; other site
926550012951	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
926550012952	intersubunit interface [polypeptide binding]; other site
926550012953	active site
926550012954	Zn2+ binding site [ion binding]; other site
926550012955	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
926550012956	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
926550012957	putative substrate binding site [chemical binding]; other site
926550012958	putative ATP binding site [chemical binding]; other site
926550012959	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
926550012960	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
926550012961	Domain of unknown function (DUF4129); Region: DUF4129; pfam13559
926550012962	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
926550012963	RNA binding site [nucleotide binding]; other site
926550012964	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
926550012965	RNA binding site [nucleotide binding]; other site
926550012966	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
926550012967	RNA binding site [nucleotide binding]; other site
926550012968	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
926550012969	RNA binding site [nucleotide binding]; other site
926550012970	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
926550012971	rRNA binding site [nucleotide binding]; other site
926550012972	predicted 30S ribosome binding site; other site
926550012973	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
926550012974	active site
926550012975	Ap6A binding site [chemical binding]; other site
926550012976	nudix motif; other site
926550012977	metal binding site [ion binding]; metal-binding site
926550012978	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
926550012979	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
926550012980	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
926550012981	FeoA domain; Region: FeoA; pfam04023
926550012982	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
926550012983	transmembrane helices; other site
926550012984	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
926550012985	TrkA-C domain; Region: TrkA_C; pfam02080
926550012986	TrkA-C domain; Region: TrkA_C; pfam02080
926550012987	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
926550012988	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
926550012989	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
926550012990	active site
926550012991	SUMO-1 interface [polypeptide binding]; other site
926550012992	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
926550012993	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
926550012994	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550012995	catalytic residue [active]
926550012996	non-metazoan 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_Sc; cd01414
926550012997	active site
926550012998	ATP binding site [chemical binding]; other site
926550012999	substrate binding site [chemical binding]; other site
926550013000	putative acyltransferase; Provisional; Region: PRK05790
926550013001	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
926550013002	dimer interface [polypeptide binding]; other site
926550013003	active site
926550013004	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550013005	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926550013006	substrate binding pocket [chemical binding]; other site
926550013007	membrane-bound complex binding site; other site
926550013008	hinge residues; other site
926550013009	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
926550013010	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
926550013011	substrate binding pocket [chemical binding]; other site
926550013012	membrane-bound complex binding site; other site
926550013013	hinge residues; other site
926550013014	XdhC Rossmann domain; Region: XdhC_C; pfam13478
926550013015	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
926550013016	2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases [Coenzyme metabolism / Energy production and conversion]; Region: UbiB; COG0543
926550013017	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
926550013018	FAD binding pocket [chemical binding]; other site
926550013019	conserved FAD binding motif [chemical binding]; other site
926550013020	phosphate binding motif [ion binding]; other site
926550013021	beta-alpha-beta structure motif; other site
926550013022	NAD binding pocket [chemical binding]; other site
926550013023	Methyltransferase domain; Region: Methyltransf_31; pfam13847
926550013024	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
926550013025	S-adenosylmethionine binding site [chemical binding]; other site
926550013026	Zn-dependent carboxypeptidase [Amino acid transport and metabolism]; Region: COG2317
926550013027	Peptidase family M32 includes thermostable carboxypeptidases TaqCP and PfuCP; Region: M32_Taq; cd06460
926550013028	active site
926550013029	Zn binding site [ion binding]; other site
926550013030	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
926550013031	RNA binding site [nucleotide binding]; other site
926550013032	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
926550013033	RNA binding site [nucleotide binding]; other site
926550013034	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
926550013035	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550013036	NAD(P) binding site [chemical binding]; other site
926550013037	active site
926550013038	deoxyguanosinetriphosphate triphosphohydrolase-like protein; Provisional; Region: PRK01286
926550013039	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550013040	Zn2+ binding site [ion binding]; other site
926550013041	Mg2+ binding site [ion binding]; other site
926550013042	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
926550013043	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
926550013044	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
926550013045	Substrate binding site; other site
926550013046	Cupin domain; Region: Cupin_2; cl17218
926550013047	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
926550013048	DNA protecting protein DprA; Region: dprA; TIGR00732
926550013049	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
926550013050	Ribonucleotide Reductase R2-like protein, Mn/Fe-binding domain; Region: RNRR2_Rv0233_like; cd07911
926550013051	active site
926550013052	diiron metal binding site [ion binding]; other site
926550013053	potential frameshift: common BLAST hit: gi|222523354|ref|YP_002567824.1| D-proline reductase
926550013054	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; pfam07355
926550013055	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
926550013056	active site residue [active]
926550013057	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
926550013058	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
926550013059	cobalamin binding residues [chemical binding]; other site
926550013060	putative BtuC binding residues; other site
926550013061	dimer interface [polypeptide binding]; other site
926550013062	Predicted membrane protein [Function unknown]; Region: COG3463
926550013063	Predicted membrane protein (DUF2079); Region: DUF2079; pfam09852
926550013064	DegT/DnrJ/EryC1/StrS aminotransferase family; Region: DegT_DnrJ_EryC1; pfam01041
926550013065	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550013066	inhibitor-cofactor binding pocket; inhibition site
926550013067	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550013068	catalytic residue [active]
926550013069	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
926550013070	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
926550013071	NAD(P) binding site [chemical binding]; other site
926550013072	active site
926550013073	aconitate hydratase; Validated; Region: PRK09277
926550013074	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
926550013075	substrate binding site [chemical binding]; other site
926550013076	ligand binding site [chemical binding]; other site
926550013077	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
926550013078	substrate binding site [chemical binding]; other site
926550013079	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
926550013080	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
926550013081	active site
926550013082	Zn binding site [ion binding]; other site
926550013083	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550013084	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550013085	DNA binding site [nucleotide binding]
926550013086	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
926550013087	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
926550013088	Zn2+ binding site [ion binding]; other site
926550013089	Mg2+ binding site [ion binding]; other site
926550013090	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
926550013091	synthetase active site [active]
926550013092	NTP binding site [chemical binding]; other site
926550013093	metal binding site [ion binding]; metal-binding site
926550013094	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
926550013095	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
926550013096	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
926550013097	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
926550013098	hypothetical protein; Reviewed; Region: PRK12497
926550013099	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
926550013100	RNA/DNA hybrid binding site [nucleotide binding]; other site
926550013101	active site
926550013102	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
926550013103	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
926550013104	SH3 domain protein; Region: SH3_and_anchor; TIGR04211
926550013105	Alpha-L-arabinofuranosidase [Carbohydrate transport and metabolism]; Region: AbfA; COG3534
926550013106	Ub domain fused to Mut7-C; Region: Ub-Mut7C; pfam14451
926550013107	Uncharacterized conserved protein [Function unknown]; Region: COG1656
926550013108	Protein of unknown function DUF82; Region: DUF82; pfam01927
926550013109	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550013110	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550013111	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550013112	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
926550013113	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
926550013114	4Fe-4S binding domain; Region: Fer4; cl02805
926550013115	Polysulphide reductase, NrfD; Region: NrfD; pfam03916
926550013116	tetrathionate reductase subunit A; Provisional; Region: PRK14991
926550013117	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550013118	molybdopterin cofactor binding site; other site
926550013119	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
926550013120	This CD contains the molybdopterin_binding C-terminal (MopB_CT) region of tetrathionate reductase, subunit A, (TtrA); respiratory arsenate As(V) reductase, catalytic subunit (ArrA); and other related proteins; Region: MopB_CT_Tetrathionate_Arsenate-R; cd02780
926550013121	putative molybdopterin cofactor binding site; other site
926550013122	Cytochrome c; Region: Cytochrom_C; pfam00034
926550013123	Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191
926550013124	FmdE, Molybdenum formylmethanofuran dehydrogenase operon; Region: FmdE; pfam02663
926550013125	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; pfam01258
926550013126	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
926550013127	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
926550013128	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
926550013129	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
926550013130	active site
926550013131	rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: LasT; COG0565
926550013132	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
926550013133	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
926550013134	Double zinc ribbon; Region: DZR; pfam12773
926550013135	Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones]; Region: CcmF; COG1138
926550013136	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
926550013137	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
926550013138	catalytic residues [active]
926550013139	Cytochrome C biogenesis protein; Region: CcmH; pfam03918
926550013140	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
926550013141	Sodium Bile acid symporter family; Region: SBF; cl17470
926550013142	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
926550013143	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
926550013144	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
926550013145	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550013146	putative PBP binding loops; other site
926550013147	ABC-ATPase subunit interface; other site
926550013148	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
926550013149	putative active site [active]
926550013150	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
926550013151	rhamnose ABC transporter, rhamnose-binding protein; Region: RhaS; TIGR02637
926550013152	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550013153	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550013154	TM-ABC transporter signature motif; other site
926550013155	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
926550013156	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
926550013157	TM-ABC transporter signature motif; other site
926550013158	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
926550013159	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
926550013160	Walker A/P-loop; other site
926550013161	ATP binding site [chemical binding]; other site
926550013162	Q-loop/lid; other site
926550013163	ABC transporter signature motif; other site
926550013164	Walker B; other site
926550013165	D-loop; other site
926550013166	H-loop/switch region; other site
926550013167	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
926550013168	L-rhamnose catabolism isomerase, Pseudomonas stutzeri subtype; Region: L_rham_iso_rhiz; TIGR02629
926550013169	Predicted sugar isomerase [Cell envelope biogenesis, outer membrane]; Region: COG4952; cl17900
926550013170	oligoendopeptidase F; Region: pepF; TIGR00181
926550013171	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
926550013172	active site
926550013173	Zn binding site [ion binding]; other site
926550013174	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
926550013175	Yip1 domain; Region: Yip1; pfam04893
926550013176	Thymidylate synthase complementing protein; Region: Thy1; cl03630
926550013177	Thymidylate synthase complementing protein; Region: Thy1; cl03630
926550013178	Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only]; Region: COG2405
926550013179	Uncharacterized protein family (UPF0175); Region: UPF0175; pfam03683
926550013180	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550013181	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550013182	active site
926550013183	NTP binding site [chemical binding]; other site
926550013184	metal binding triad [ion binding]; metal-binding site
926550013185	antibiotic binding site [chemical binding]; other site
926550013186	PIN domain of the VapC-like Sll0205 protein and homologs; Region: PIN_Sll0205; cd09872
926550013187	putative active site [active]
926550013188	Antitoxin of toxin-antitoxin stability system [Cell division and chromosome partitioning]; Region: Phd; COG4118
926550013189	O-Antigen ligase; Region: Wzy_C; pfam04932
926550013190	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
926550013191	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
926550013192	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
926550013193	NAD(P) binding site [chemical binding]; other site
926550013194	homodimer interface [polypeptide binding]; other site
926550013195	substrate binding site [chemical binding]; other site
926550013196	active site
926550013197	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550013198	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926550013199	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550013200	inhibitor-cofactor binding pocket; inhibition site
926550013201	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550013202	catalytic residue [active]
926550013203	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
926550013204	ExoA is involved in the biosynthesis of succinoglycan; Region: Succinoglycan_BP_ExoA; cd02525
926550013205	Ligand binding site; other site
926550013206	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
926550013207	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550013208	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
926550013209	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
926550013210	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
926550013211	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
926550013212	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550013213	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
926550013214	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
926550013215	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
926550013216	inhibitor-cofactor binding pocket; inhibition site
926550013217	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550013218	catalytic residue [active]
926550013219	Bacterial transferase hexapeptide (six repeats); Region: Hexapep; pfam00132
926550013220	WcxM-like, Left-handed parallel beta-Helix (LbH) N-terminal domain: This group is composed of Xanthomonas campestris WcxM and proteins with similarity to the WcxM N-terminal domain. WcxM is thought to be bifunctional, catalyzing both the isomerization...; Region: LbH_WxcM_N_like; cd03358
926550013221	putative trimer interface [polypeptide binding]; other site
926550013222	putative active site [active]
926550013223	putative substrate binding site [chemical binding]; other site
926550013224	putative CoA binding site [chemical binding]; other site
926550013225	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
926550013226	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
926550013227	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
926550013228	HEPN domain; Region: HEPN; pfam05168
926550013229	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
926550013230	active site
926550013231	NTP binding site [chemical binding]; other site
926550013232	metal binding triad [ion binding]; metal-binding site
926550013233	antibiotic binding site [chemical binding]; other site
926550013234	Deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]; Region: PhrB; COG0415
926550013235	DNA photolyase; Region: DNA_photolyase; pfam00875
926550013236	Cytochrome oxidase assembly protein; Region: COX15-CtaA; pfam02628
926550013237	Cadherin repeat-like domain; Region: CA_like; cl15786
926550013238	Dystroglycan-type cadherin-like domains; Region: CADG; smart00736
926550013239	Ca2+ binding site [ion binding]; other site
926550013240	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
926550013241	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
926550013242	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
926550013243	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550013244	inhibitor-cofactor binding pocket; inhibition site
926550013245	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550013246	catalytic residue [active]
926550013247	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
926550013248	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
926550013249	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
926550013250	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
926550013251	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
926550013252	motif II; other site
926550013253	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
926550013254	tagatose 1,6-diphosphate aldolase; Reviewed; Region: PRK12858
926550013255	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
926550013256	active site
926550013257	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cl00197
926550013258	active site
926550013259	Thioredoxin domain; Region: Thioredoxin_3; pfam13192
926550013260	Predicted permease; Region: DUF318; cl17795
926550013261	Predicted permease; Region: DUF318; cl17795
926550013262	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550013263	dimerization interface [polypeptide binding]; other site
926550013264	putative DNA binding site [nucleotide binding]; other site
926550013265	putative Zn2+ binding site [ion binding]; other site
926550013266	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
926550013267	tungsten cofactor oxidoreducase radical SAM maturase; Region: W_rSAM_matur; TIGR04317
926550013268	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
926550013269	FeS/SAM binding site; other site
926550013270	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
926550013271	Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism]; Region: ACR3; COG0798
926550013272	arsenical-resistance protein; Region: acr3; TIGR00832
926550013273	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
926550013274	dimerization interface [polypeptide binding]; other site
926550013275	putative DNA binding site [nucleotide binding]; other site
926550013276	putative Zn2+ binding site [ion binding]; other site
926550013277	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
926550013278	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
926550013279	NAD(P) binding pocket [chemical binding]; other site
926550013280	2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; Region: Eda; COG0800
926550013281	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
926550013282	active site
926550013283	intersubunit interface [polypeptide binding]; other site
926550013284	catalytic residue [active]
926550013285	Putative D-3-Phosphoglycerate Dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_like_2; cd12172
926550013286	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
926550013287	putative ligand binding site [chemical binding]; other site
926550013288	putative NAD binding site [chemical binding]; other site
926550013289	catalytic site [active]
926550013290	Glucose-6-phosphate isomerase (GPI); Region: GPI; pfam06560
926550013291	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
926550013292	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
926550013293	DNA-binding site [nucleotide binding]; DNA binding site
926550013294	UTRA domain; Region: UTRA; pfam07702
926550013295	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
926550013296	uncharacterized xylulose kinase-like proteins; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_XK_like_1; cd07804
926550013297	N- and C-terminal domain interface [polypeptide binding]; other site
926550013298	putative active site [active]
926550013299	MgATP binding site [chemical binding]; other site
926550013300	catalytic site [active]
926550013301	metal binding site [ion binding]; metal-binding site
926550013302	putative xylulose binding site [chemical binding]; other site
926550013303	putative homodimer interface [polypeptide binding]; other site
926550013304	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
926550013305	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550013306	dimer interface [polypeptide binding]; other site
926550013307	conserved gate region; other site
926550013308	putative PBP binding loops; other site
926550013309	ABC-ATPase subunit interface; other site
926550013310	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
926550013311	dimer interface [polypeptide binding]; other site
926550013312	conserved gate region; other site
926550013313	putative PBP binding loops; other site
926550013314	ABC-ATPase subunit interface; other site
926550013315	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
926550013316	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
926550013317	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
926550013318	T4-like virus tail tube protein gp19; Region: Phage_T4_gp19; pfam06841
926550013319	Protein of unknown function (DUF4255); Region: DUF4255; pfam14065
926550013320	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
926550013321	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
926550013322	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
926550013323	Walker A motif; other site
926550013324	ATP binding site [chemical binding]; other site
926550013325	Walker B motif; other site
926550013326	arginine finger; other site
926550013327	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
926550013328	Phage-related baseplate assembly protein; Region: Phage_base_V; pfam04717
926550013329	Domain of unknown function (DUF4280); Region: DUF4280; pfam14107
926550013330	Gene 25-like lysozyme; Region: GPW_gp25; pfam04965
926550013331	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
926550013332	conserved hypothetical protein, phage tail-like region; Region: TIGR02243
926550013333	phage tail protein domain; Region: tail_TIGR02242
926550013334	Domain of unknown function (DUF4157); Region: DUF4157; pfam13699
926550013335	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
926550013336	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; cl11421
926550013337	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
926550013338	homoserine O-acetyltransferase; Provisional; Region: metX; cl17114
926550013339	Flavin reductase like domain; Region: Flavin_Reduct; smart00903
926550013340	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
926550013341	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
926550013342	active site
926550013343	catalytic residues [active]
926550013344	metal binding site [ion binding]; metal-binding site
926550013345	DmpG-like communication domain; Region: DmpG_comm; pfam07836
926550013346	acetaldehyde dehydrogenase; Validated; Region: PRK08300
926550013347	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926550013348	Prokaryotic acetaldehyde dehydrogenase, dimerisation; Region: AcetDehyd-dimer; pfam09290
926550013349	Transcriptional regulator [Transcription]; Region: IclR; COG1414
926550013350	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
926550013351	Bacterial transcriptional regulator; Region: IclR; pfam01614
926550013352	N-terminal, non-catalytic, domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase) from Bacillus sp. JF8 and similar proteins; Region: BphC-JF8_N_like; cd09013
926550013353	tetramer interface [polypeptide binding]; other site
926550013354	catechol 2,3 dioxygenase; Region: catechol_2_3; TIGR03211
926550013355	C-terminal, catalytic, domain of BphC_JF8, (2,3-dihydroxybiphenyl 1,2-dioxygenase) from Bacillus sp. JF8 and similar proteins; Region: BphC-JF8_C_like; cd09014
926550013356	tetramer interface [polypeptide binding]; other site
926550013357	active site
926550013358	metal binding site [ion binding]; metal-binding site
926550013359	4-hydroxyphenylacetate 3-monooxygenase, oxygenase component; Region: HpaB-2; TIGR02310
926550013360	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
926550013361	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
926550013362	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
926550013363	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
926550013364	Bacterial SH3 domain; Region: SH3_4; pfam06347
926550013365	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl17364
926550013366	acetyl-lysine deacetylase; Provisional; Region: PRK04443
926550013367	M20 Peptidase acetylornithine deacetylase/acetyl-lysine deacetylase; Region: M20_ArgE_LysK; cd05653
926550013368	metal binding site [ion binding]; metal-binding site
926550013369	putative dimer interface [polypeptide binding]; other site
926550013370	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
926550013371	acetylornithine aminotransferase; Provisional; Region: PRK02627
926550013372	inhibitor-cofactor binding pocket; inhibition site
926550013373	pyridoxal 5'-phosphate binding site [chemical binding]; other site
926550013374	catalytic residue [active]
926550013375	AAK_NAGK-UC: N-Acetyl-L-glutamate kinase - uncharacterized (NAGK-UC). This domain is similar to Escherichia coli and Pseudomonas aeruginosa NAGKs which catalyze the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the...; Region: AAK_NAGK-UC; cd04251
926550013376	putative nucleotide binding site [chemical binding]; other site
926550013377	putative N-acetyl-L-glutamate binding site [chemical binding]; other site
926550013378	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
926550013379	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
926550013380	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
926550013381	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
926550013382	active site
926550013383	phosphorylation site [posttranslational modification]
926550013384	intermolecular recognition site; other site
926550013385	dimerization interface [polypeptide binding]; other site
926550013386	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
926550013387	DNA binding site [nucleotide binding]
926550013388	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
926550013389	rRNA interaction site [nucleotide binding]; other site
926550013390	S8 interaction site; other site
926550013391	putative laminin-1 binding site; other site
926550013392	elongation factor Ts; Reviewed; Region: tsf; PRK12332
926550013393	UBA/TS-N domain; Region: UBA; pfam00627
926550013394	Elongation factor TS; Region: EF_TS; pfam00889
926550013395	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
926550013396	putative nucleotide binding site [chemical binding]; other site
926550013397	uridine monophosphate binding site [chemical binding]; other site
926550013398	homohexameric interface [polypeptide binding]; other site
926550013399	ribosome recycling factor; Reviewed; Region: frr; PRK00083
926550013400	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
926550013401	hinge region; other site
926550013402	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
926550013403	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
926550013404	catalytic residue [active]
926550013405	putative FPP diphosphate  binding site; other site
926550013406	putative FPP binding hydrophobic cleft; other site
926550013407	dimer interface [polypeptide binding]; other site
926550013408	putative IPP diphosphate binding site; other site
926550013409	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
926550013410	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
926550013411	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
926550013412	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
926550013413	substrate binding site [chemical binding]; other site
926550013414	hexamer interface [polypeptide binding]; other site
926550013415	metal binding site [ion binding]; metal-binding site
926550013416	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
926550013417	Protein of unknown function (DUF971); Region: DUF971; pfam06155
926550013418	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
926550013419	Coenzyme A binding pocket [chemical binding]; other site