-- dump date   	20140619_021954
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1211776000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1211776000002	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776000003	Walker A motif; other site
1211776000004	ATP binding site [chemical binding]; other site
1211776000005	Walker B motif; other site
1211776000006	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1211776000007	DnaA box-binding interface [nucleotide binding]; other site
1211776000008	DNA polymerase III subunit beta; Validated; Region: PRK05643
1211776000009	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1211776000010	putative DNA binding surface [nucleotide binding]; other site
1211776000011	dimer interface [polypeptide binding]; other site
1211776000012	beta-clamp/clamp loader binding surface; other site
1211776000013	beta-clamp/translesion DNA polymerase binding surface; other site
1211776000014	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
1211776000015	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776000016	Mg2+ binding site [ion binding]; other site
1211776000017	G-X-G motif; other site
1211776000018	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1211776000019	anchoring element; other site
1211776000020	dimer interface [polypeptide binding]; other site
1211776000021	ATP binding site [chemical binding]; other site
1211776000022	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1211776000023	active site
1211776000024	putative metal-binding site [ion binding]; other site
1211776000025	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1211776000026	quinohemoprotein amine dehydrogenase, alpha subunit; Region: QH_alpha; TIGR03908
1211776000027	sulfite oxidase; Provisional; Region: PLN00177
1211776000028	Subgroup of sulfite oxidase (SO) family molybdopterin binding domains that contains conserved dimerization domain. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate...; Region: SO_family_Moco_dimer; cd02110
1211776000029	Moco binding site; other site
1211776000030	metal coordination site [ion binding]; other site
1211776000031	dimerization interface [polypeptide binding]; other site
1211776000032	Predicted permease [General function prediction only]; Region: COG2056
1211776000033	Na+-H+ antiporter family; Region: Na_H_antiport_2; pfam13726
1211776000034	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
1211776000035	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
1211776000036	active site
1211776000037	dimer interface [polypeptide binding]; other site
1211776000038	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
1211776000039	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1211776000040	active site
1211776000041	FMN binding site [chemical binding]; other site
1211776000042	substrate binding site [chemical binding]; other site
1211776000043	3Fe-4S cluster binding site [ion binding]; other site
1211776000044	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
1211776000045	domain interface; other site
1211776000046	Protein of unknown function DUF262; Region: DUF262; pfam03235
1211776000047	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1211776000048	glutamate synthase subunit beta; Reviewed; Region: gltD; PRK12810
1211776000049	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1211776000050	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1211776000051	RNA/DNA hybrid binding site [nucleotide binding]; other site
1211776000052	active site
1211776000053	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1211776000054	Helix-hairpin-helix motif; Region: HHH; pfam00633
1211776000056	Desulforedoxin (DSRD) domain; a small non-heme iron domain present in the desulforedoxin (rubredoxin oxidoreductase) and desulfoferrodoxin proteins of some archeael and bacterial methanogens and sulfate/sulfur reducers. Desulforedoxin is a small; Region: DSRD; cd00974
1211776000057	non-heme iron binding site [ion binding]; other site
1211776000058	dimer interface [polypeptide binding]; other site
1211776000059	Rubrerythrin [Energy production and conversion]; Region: COG1592
1211776000060	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1211776000061	binuclear metal center [ion binding]; other site
1211776000062	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
1211776000063	iron binding site [ion binding]; other site
1211776000064	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1211776000065	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
1211776000067	Competence protein ComGF [Intracellular trafficking and secretion]; Region: ComGF; COG4940
1211776000068	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
1211776000069	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1211776000070	Ligand Binding Site [chemical binding]; other site
1211776000071	Disulfide bond formation protein DsbB [Posttranslational modification, protein turnover, chaperones]; Region: DsbB; COG1495
1211776000074	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776000075	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776000076	dimer interface [polypeptide binding]; other site
1211776000077	putative CheW interface [polypeptide binding]; other site
1211776000079	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1211776000080	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
1211776000081	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
1211776000082	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1211776000083	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1211776000084	active site
1211776000085	adenylosuccinate lyase; Provisional; Region: PRK08470
1211776000086	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1211776000087	tetramer interface [polypeptide binding]; other site
1211776000088	active site
1211776000089	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1211776000090	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08447
1211776000091	ATP cone domain; Region: ATP-cone; pfam03477
1211776000092	Class I ribonucleotide reductase; Region: RNR_I; cd01679
1211776000093	active site
1211776000094	dimer interface [polypeptide binding]; other site
1211776000095	catalytic residues [active]
1211776000096	effector binding site; other site
1211776000097	R2 peptide binding site; other site
1211776000098	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1211776000099	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1211776000101	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1211776000102	CTP synthetase; Validated; Region: pyrG; PRK05380
1211776000103	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1211776000104	Catalytic site [active]
1211776000105	active site
1211776000106	UTP binding site [chemical binding]; other site
1211776000107	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1211776000108	active site
1211776000109	putative oxyanion hole; other site
1211776000110	catalytic triad [active]
1211776000112	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1211776000113	DHH family; Region: DHH; pfam01368
1211776000114	DHHA1 domain; Region: DHHA1; pfam02272
1211776000115	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
1211776000116	active site
1211776000117	homodimer interface [polypeptide binding]; other site
1211776000118	homotetramer interface [polypeptide binding]; other site
1211776000119	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_4; pfam14281
1211776000120	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1211776000121	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1211776000122	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1211776000123	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
1211776000125	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2859
1211776000127	drug resistance transporter, Bcr/CflA subfamily; Region: efflux_Bcr_CflA; TIGR00710
1211776000128	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776000129	putative substrate translocation pore; other site
1211776000131	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4487
1211776000132	Uncharacterized protein conserved in bacteria (DUF2130); Region: DUF2130; pfam09903
1211776000133	Cytochrome c [Energy production and conversion]; Region: COG3258
1211776000134	Cytochrome c; Region: Cytochrom_C; pfam00034
1211776000135	Cytochrome c; Region: Cytochrom_C; pfam00034
1211776000137	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1211776000138	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1211776000139	G1 box; other site
1211776000140	putative GEF interaction site [polypeptide binding]; other site
1211776000141	GTP/Mg2+ binding site [chemical binding]; other site
1211776000142	Switch I region; other site
1211776000143	G2 box; other site
1211776000144	G3 box; other site
1211776000145	Switch II region; other site
1211776000146	G4 box; other site
1211776000147	G5 box; other site
1211776000148	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1211776000149	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1211776000150	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1211776000151	Flagellar hook capping protein [Cell motility and secretion]; Region: FlgD; COG1843
1211776000152	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1211776000153	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
1211776000154	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
1211776000155	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1211776000156	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1211776000157	Hemerythrin; Region: Hemerythrin; cd12107
1211776000158	Fe binding site [ion binding]; other site
1211776000162	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1211776000163	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1211776000164	Ligand Binding Site [chemical binding]; other site
1211776000165	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
1211776000166	A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various...; Region: Peptidase_C39G; cd02423
1211776000167	putative active site [active]
1211776000168	flagellar motor switch protein FliY; Validated; Region: PRK08432
1211776000169	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1211776000170	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1211776000171	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1211776000172	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
1211776000173	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1211776000175	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
1211776000176	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1211776000177	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
1211776000178	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
1211776000179	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1211776000180	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1211776000181	catalytic center binding site [active]
1211776000182	ATP binding site [chemical binding]; other site
1211776000183	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1211776000184	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1211776000185	trimer interface [polypeptide binding]; other site
1211776000186	active site
1211776000187	dimer interface [polypeptide binding]; other site
1211776000188	chlorohydrolase; Provisional; Region: PRK08418
1211776000189	Metallo-dependent hydrolases, subgroup D is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_D; cd01312
1211776000190	active site
1211776000191	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1211776000192	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1211776000193	tandem repeat interface [polypeptide binding]; other site
1211776000194	oligomer interface [polypeptide binding]; other site
1211776000195	active site residues [active]
1211776000197	Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) [Coenzyme metabolism / Translation, ribosomal structure and biogenesis]; Region: RimK; COG0189
1211776000199	Uncharacterized conserved protein [Function unknown]; Region: COG1556
1211776000200	Uncharacterized conserved protein containing a ferredoxin-like domain [Energy production and conversion]; Region: COG1139
1211776000201	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1211776000202	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1211776000203	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
1211776000204	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1211776000205	Cysteine-rich domain; Region: CCG; pfam02754
1211776000206	Cysteine-rich domain; Region: CCG; pfam02754
1211776000207	L-lactate permease; Region: Lactate_perm; cl00701
1211776000208	L-lactate permease [Energy production and conversion]; Region: LldP; COG1620
1211776000210	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
1211776000211	CdtB, the catalytic DNase I-like subunit of cytolethal distending toxin (CDT) protein; Region: CdtB; cd09081
1211776000212	putative catalytic site [active]
1211776000213	CdtC interface [polypeptide binding]; other site
1211776000214	heterotrimer interface [polypeptide binding]; other site
1211776000215	CdtA interface [polypeptide binding]; other site
1211776000216	putative metal binding site [ion binding]; other site
1211776000217	putative phosphate binding site [ion binding]; other site
1211776000218	Cytolethal distending toxin A/C family; Region: CDtoxinA; pfam03498
1211776000219	Ricin-type beta-trefoil; Carbohydrate-binding domain formed from presumed gene triplication. The domain is found in a variety of molecules serving diverse functions such as enzymatic activity, inhibitory toxicity and signal transduction. Highly specific...; Region: RICIN; cd00161
1211776000220	putative sugar binding sites [chemical binding]; other site
1211776000221	Q-X-W motif; other site
1211776000224	Cytochrome bd-type quinol oxidase, subunit 1 [Energy production and conversion]; Region: CydA; COG1271
1211776000225	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
1211776000227	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
1211776000228	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
1211776000230	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
1211776000231	aspartate racemase; Region: asp_race; TIGR00035
1211776000232	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1211776000233	ligand binding site [chemical binding]; other site
1211776000234	active site
1211776000235	UGI interface [polypeptide binding]; other site
1211776000236	catalytic site [active]
1211776000237	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
1211776000238	Aspartase; Region: Aspartase; cd01357
1211776000239	active sites [active]
1211776000240	tetramer interface [polypeptide binding]; other site
1211776000241	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1211776000242	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
1211776000244	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3014
1211776000245	Predicted periplasmic lipoprotein [General function prediction only]; Region: COG5633
1211776000246	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
1211776000247	putative dimer interface [polypeptide binding]; other site
1211776000248	uncharacterized proteobacterial lipoprotein; Region: lp_; TIGR02722
1211776000250	Curli production assembly/transport component CsgG; Region: CsgG; cl17434
1211776000251	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1211776000252	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1211776000253	GTPase CgtA; Reviewed; Region: obgE; PRK12299
1211776000254	GTP1/OBG; Region: GTP1_OBG; pfam01018
1211776000255	Obg GTPase; Region: Obg; cd01898
1211776000256	G1 box; other site
1211776000257	GTP/Mg2+ binding site [chemical binding]; other site
1211776000258	Switch I region; other site
1211776000259	G2 box; other site
1211776000260	G3 box; other site
1211776000261	Switch II region; other site
1211776000262	G4 box; other site
1211776000263	G5 box; other site
1211776000264	Glutamate 5-kinase [Amino acid transport and metabolism]; Region: ProB; COG0263
1211776000265	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1211776000266	nucleotide binding site [chemical binding]; other site
1211776000267	homotetrameric interface [polypeptide binding]; other site
1211776000268	putative phosphate binding site [ion binding]; other site
1211776000269	putative allosteric binding site; other site
1211776000270	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1211776000271	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1211776000272	putative active site [active]
1211776000273	substrate binding site [chemical binding]; other site
1211776000274	putative cosubstrate binding site; other site
1211776000275	catalytic site [active]
1211776000276	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1211776000277	substrate binding site [chemical binding]; other site
1211776000278	biotin--protein ligase; Provisional; Region: PRK08477
1211776000279	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
1211776000280	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1211776000281	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1211776000282	P-loop; other site
1211776000283	Magnesium ion binding site [ion binding]; other site
1211776000284	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1211776000285	Magnesium ion binding site [ion binding]; other site
1211776000286	ParB-like nuclease domain; Region: ParB; smart00470
1211776000287	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1211776000288	F0F1 ATP synthase subunit B'; Validated; Region: PRK08476
1211776000289	F0F1-type ATP synthase, subunit b [Energy production and conversion]; Region: AtpF; COG0711
1211776000291	F0F1 ATP synthase subunit B; Validated; Region: PRK08475
1211776000293	F0F1 ATP synthase subunit delta; Validated; Region: PRK08474
1211776000294	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1211776000295	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1211776000296	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1211776000297	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1211776000298	beta subunit interaction interface [polypeptide binding]; other site
1211776000299	Walker A motif; other site
1211776000300	ATP binding site [chemical binding]; other site
1211776000301	Walker B motif; other site
1211776000302	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1211776000303	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1211776000304	core domain interface [polypeptide binding]; other site
1211776000305	delta subunit interface [polypeptide binding]; other site
1211776000306	epsilon subunit interface [polypeptide binding]; other site
1211776000307	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1211776000308	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1211776000309	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1211776000310	alpha subunit interaction interface [polypeptide binding]; other site
1211776000311	Walker A motif; other site
1211776000312	ATP binding site [chemical binding]; other site
1211776000313	Walker B motif; other site
1211776000314	inhibitor binding site; inhibition site
1211776000315	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1211776000316	ATP synthase, F1 epsilon subunit (delta in mitochondria); Region: ATP_synt_epsi; TIGR01216
1211776000317	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1211776000318	gamma subunit interface [polypeptide binding]; other site
1211776000319	epsilon subunit interface [polypeptide binding]; other site
1211776000320	LBP interface [polypeptide binding]; other site
1211776000321	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1211776000323	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1211776000324	TolR protein; Region: tolR; TIGR02801
1211776000326	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1211776000327	TonB C terminal; Region: TonB_2; pfam13103
1211776000329	translocation protein TolB; Provisional; Region: tolB; PRK04043
1211776000330	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1211776000331	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1211776000332	ligand binding site [chemical binding]; other site
1211776000333	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
1211776000334	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
1211776000335	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1211776000336	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1211776000337	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1211776000338	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1211776000339	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1211776000340	Ligand Binding Site [chemical binding]; other site
1211776000341	Isochorismatase family; Region: Isochorismatase; pfam00857
1211776000342	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1211776000343	catalytic triad [active]
1211776000344	conserved cis-peptide bond; other site
1211776000345	putative recombination protein RecO; Provisional; Region: PRK13908
1211776000346	metal-binding heat shock protein; Provisional; Region: PRK00016
1211776000347	tRNA-dihydrouridine synthase [Translation, ribosomal structure and biogenesis]; Region: COG0042
1211776000348	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1211776000349	FMN binding site [chemical binding]; other site
1211776000350	active site
1211776000351	catalytic residues [active]
1211776000352	substrate binding site [chemical binding]; other site
1211776000354	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
1211776000355	Uncharacterized conserved protein [Function unknown]; Region: COG1576
1211776000356	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1211776000357	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1211776000358	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1211776000359	Putative fructose-1,6-bisphosphatase or related enzymes of inositol monophosphatase family. These are Mg++ dependent phosphatases. Members in this family may have fructose-1,6-bisphosphatase and/or inositol-monophosphatase activity. Fructose-1; Region: Arch_FBPase_2; cd01642
1211776000360	putative active site [active]
1211776000362	outer membrane protein assembly complex, YaeT protein; Region: OM_YaeT; TIGR03303
1211776000363	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1211776000364	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1211776000365	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
1211776000366	Surface antigen; Region: Bac_surface_Ag; pfam01103
1211776000367	prephenate dehydrogenase; Validated; Region: PRK08507
1211776000368	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
1211776000369	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1211776000370	Peptidase family M23; Region: Peptidase_M23; pfam01551
1211776000372	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
1211776000373	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
1211776000374	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
1211776000375	Homoserine kinase [Amino acid transport and metabolism]; Region: ThrB; COG0083
1211776000376	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1211776000377	Predicted nucleic-acid-binding protein implicated in transcription termination [Transcription]; Region: COG2740
1211776000378	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1211776000379	translation initiation factor IF-2; Region: IF-2; TIGR00487
1211776000380	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1211776000381	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1211776000382	G1 box; other site
1211776000383	putative GEF interaction site [polypeptide binding]; other site
1211776000384	GTP/Mg2+ binding site [chemical binding]; other site
1211776000385	Switch I region; other site
1211776000386	G2 box; other site
1211776000387	G3 box; other site
1211776000388	Switch II region; other site
1211776000389	G4 box; other site
1211776000390	G5 box; other site
1211776000391	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1211776000392	Translation-initiation factor 2; Region: IF-2; pfam11987
1211776000393	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1211776000394	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1211776000395	Uncharacterized BCR, YhbC family COG0779; Region: DUF150; pfam02576
1211776000396	Sm and related proteins; Region: Sm_like; cl00259
1211776000397	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1211776000398	putative oligomer interface [polypeptide binding]; other site
1211776000399	putative RNA binding site [nucleotide binding]; other site
1211776000400	GTPase subunit of restriction endonuclease [Defense mechanisms]; Region: McrB; COG1401
1211776000401	AAA domain (dynein-related subfamily); Region: AAA_5; pfam07728
1211776000402	McrBC 5-methylcytosine restriction system component [Defense mechanisms]; Region: McrC; COG4268
1211776000403	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1211776000404	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1211776000405	dimer interface [polypeptide binding]; other site
1211776000406	putative PBP binding regions; other site
1211776000407	ABC-ATPase subunit  interface; other site
1211776000409	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1211776000410	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1211776000411	Metal binding protein ZntC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions.  They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding...; Region: ZntC; cd01018
1211776000412	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1211776000413	putative metal binding residues [ion binding]; other site
1211776000414	Cache domain; Region: Cache_1; pfam02743
1211776000415	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776000416	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776000417	dimer interface [polypeptide binding]; other site
1211776000418	putative CheW interface [polypeptide binding]; other site
1211776000420	Predicted phosphatase [General function prediction only]; Region: PhoX; COG3211
1211776000421	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1211776000422	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1211776000423	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1211776000424	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1211776000425	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1211776000426	catalytic residues [active]
1211776000427	Predicted endonuclease distantly related to archaeal Holliday junction resolvase [DNA replication, recombination, and repair]; Region: COG0792
1211776000428	homoserine dehydrogenase; Provisional; Region: PRK06349
1211776000429	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1211776000430	ACT_HSDH_Hom CD includes the C-terminal ACT domain of the NAD(P)H-dependent, homoserine dehydrogenase (HSDH) and related domains; Region: ACT_HSDH-Hom; cd04881
1211776000431	aspartate aminotransferase; Provisional; Region: PRK08636
1211776000432	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1211776000433	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776000434	homodimer interface [polypeptide binding]; other site
1211776000435	catalytic residue [active]
1211776000436	Helix-turn-helix domain; Region: HTH_25; pfam13413
1211776000438	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1211776000439	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1211776000440	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1211776000441	Predicted methyltransferases [General function prediction only]; Region: COG0313
1211776000442	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1211776000443	putative SAM binding site [chemical binding]; other site
1211776000444	putative homodimer interface [polypeptide binding]; other site
1211776000445	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1211776000446	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1385
1211776000448	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1211776000449	queuosine biosynthesis protein QueD; Region: queuosine_QueD; TIGR03367
1211776000450	active site
1211776000451	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
1211776000452	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776000453	FeS/SAM binding site; other site
1211776000454	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1211776000455	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776000456	FeS/SAM binding site; other site
1211776000457	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1211776000459	prenyltransferase; Reviewed; Region: ubiA; PRK12874
1211776000460	UbiA prenyltransferase family; Region: UbiA; pfam01040
1211776000462	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1211776000463	tRNA dimethylallyltransferase; Region: miaA; TIGR00174
1211776000464	Predicted membrane protein [Function unknown]; Region: COG1971
1211776000465	Domain of unknown function DUF; Region: DUF204; pfam02659
1211776000468	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
1211776000469	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
1211776000470	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1211776000471	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1211776000472	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776000473	S-adenosylmethionine binding site [chemical binding]; other site
1211776000474	Protein of unknown function (DUF3500); Region: DUF3500; pfam12006
1211776000475	Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism]; Region: LYS9; COG1748
1211776000476	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1211776000477	NAD(P) binding pocket [chemical binding]; other site
1211776000478	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1211776000479	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1211776000480	Walker A/P-loop; other site
1211776000481	ATP binding site [chemical binding]; other site
1211776000482	Q-loop/lid; other site
1211776000483	ABC transporter signature motif; other site
1211776000484	Walker B; other site
1211776000485	D-loop; other site
1211776000486	H-loop/switch region; other site
1211776000487	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1211776000488	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776000489	dimer interface [polypeptide binding]; other site
1211776000490	conserved gate region; other site
1211776000491	putative PBP binding loops; other site
1211776000492	ABC-ATPase subunit interface; other site
1211776000493	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776000494	dimer interface [polypeptide binding]; other site
1211776000495	conserved gate region; other site
1211776000496	putative PBP binding loops; other site
1211776000497	ABC-ATPase subunit interface; other site
1211776000499	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
1211776000500	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1211776000501	Uncharacterized iron-regulated protein [Function unknown]; Region: PhuW; COG3016
1211776000502	TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein; Region: TonB-hemlactrns; TIGR01786
1211776000503	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
1211776000504	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
1211776000506	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1211776000507	Biopolymer transport protein ExbD/TolR; Region: ExbD; cl00537
1211776000509	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1211776000510	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1211776000512	ABC-type long-chain fatty acid transport system, fused permease and ATPase components [Lipid metabolism]; Region: SbmA; COG1133
1211776000514	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1211776000515	Domain of unknown function DUF21; Region: DUF21; pfam01595
1211776000516	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1211776000517	Transporter associated domain; Region: CorC_HlyC; smart01091
1211776000519	Predicted kinase [General function prediction only]; Region: COG4639
1211776000520	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1211776000521	phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain; Region: MPP_PPP_family; cd00144
1211776000522	active site
1211776000523	metal binding site [ion binding]; metal-binding site
1211776000524	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1211776000525	PhnA protein; Region: PhnA; pfam03831
1211776000526	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
1211776000528	Folate-dependent phosphoribosylglycinamide formyltransferase PurN [Nucleotide transport and metabolism]; Region: PurN; COG0299
1211776000529	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
1211776000530	active site
1211776000531	substrate binding site [chemical binding]; other site
1211776000532	cosubstrate binding site; other site
1211776000533	catalytic site [active]
1211776000534	Uncharacterized conserved protein [Function unknown]; Region: COG0062
1211776000535	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1211776000536	putative substrate binding site [chemical binding]; other site
1211776000537	putative ATP binding site [chemical binding]; other site
1211776000538	Uncharacterized conserved protein [Function unknown]; Region: COG1432
1211776000539	Uncharacterized subfamily of N-terminal LabA-like domains; Region: LabA_like_N_1; cd11297
1211776000540	putative metal binding site [ion binding]; other site
1211776000541	C-terminal domain of LabA_like proteins; Region: LabA_like_C; cd10146
1211776000542	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1211776000543	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1211776000544	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1211776000545	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1211776000546	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1211776000547	active site
1211776000548	catalytic residues [active]
1211776000549	metal binding site [ion binding]; metal-binding site
1211776000550	Clp protease; Region: CLP_protease; pfam00574
1211776000551	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1211776000552	oligomer interface [polypeptide binding]; other site
1211776000553	active site residues [active]
1211776000554	trigger factor; Provisional; Region: tig; PRK01490
1211776000555	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1211776000556	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1211776000557	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1211776000558	homodecamer interface [polypeptide binding]; other site
1211776000559	GTP cyclohydrolase I; Provisional; Region: PLN03044
1211776000560	active site
1211776000561	putative catalytic site residues [active]
1211776000562	zinc binding site [ion binding]; other site
1211776000563	GTP-CH-I/GFRP interaction surface; other site
1211776000564	flagellum-specific ATP synthase; Validated; Region: fliI; PRK08472
1211776000565	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1211776000566	Walker A motif/ATP binding site; other site
1211776000567	Walker B motif; other site
1211776000568	amidophosphoribosyltransferase; Provisional; Region: PRK08525
1211776000569	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
1211776000570	active site
1211776000571	tetramer interface [polypeptide binding]; other site
1211776000572	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776000573	active site
1211776000574	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1211776000575	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1211776000576	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1211776000577	ATPase related to the helicase subunit of the Holliday junction resolvase [DNA replication, recombination, and repair]; Region: MGS1; COG2256
1211776000578	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776000579	Walker A motif; other site
1211776000580	ATP binding site [chemical binding]; other site
1211776000581	Walker B motif; other site
1211776000582	arginine finger; other site
1211776000583	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1211776000585	Orthopoxvirus protein of unknown function (DUF830); Region: DUF830; cl13998
1211776000587	Lumazine-binding domain; Region: Lumazine_bd; pfam12870
1211776000588	H+/citrate symporter [Energy production and conversion]; Region: CitM; COG2851
1211776000589	Citrate transporter; Region: CitMHS; pfam03600
1211776000591	Predicted membrane protein [Function unknown]; Region: COG1297
1211776000592	putative oligopeptide transporter, OPT family; Region: TIGR00733
1211776000594	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1211776000596	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK12305
1211776000597	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1211776000598	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1211776000599	active site
1211776000600	dimer interface [polypeptide binding]; other site
1211776000601	motif 1; other site
1211776000602	motif 2; other site
1211776000603	motif 3; other site
1211776000604	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1211776000605	anticodon binding site; other site
1211776000606	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1211776000607	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1211776000608	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1211776000609	Adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG3392
1211776000610	D12 class N6 adenine-specific DNA methyltransferase; Region: MethyltransfD12; cl17344
1211776000612	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1211776000613	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1211776000614	putative acetyltransferase YhhY; Provisional; Region: PRK10140
1211776000615	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776000616	Coenzyme A binding pocket [chemical binding]; other site
1211776000617	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
1211776000618	feedback inhibition sensing region; other site
1211776000619	homohexameric interface [polypeptide binding]; other site
1211776000620	nucleotide binding site [chemical binding]; other site
1211776000621	N-acetyl-L-glutamate binding site [chemical binding]; other site
1211776000622	Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Region: ArgD; COG4992
1211776000623	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1211776000624	inhibitor-cofactor binding pocket; inhibition site
1211776000625	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776000626	catalytic residue [active]
1211776000627	protein-L-isoaspartate O-methyltransferase; Reviewed; Region: pcm; PRK00312
1211776000628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776000629	S-adenosylmethionine binding site [chemical binding]; other site
1211776000630	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1211776000631	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1211776000632	trimer interface [polypeptide binding]; other site
1211776000633	putative metal binding site [ion binding]; other site
1211776000634	putative nicotinate phosphoribosyltransferase; Region: NAPRTase_put; TIGR01513
1211776000635	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1211776000636	active site
1211776000637	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
1211776000638	dimer interface [polypeptide binding]; other site
1211776000639	putative radical transfer pathway; other site
1211776000640	diiron center [ion binding]; other site
1211776000641	tyrosyl radical; other site
1211776000642	RDD family; Region: RDD; pfam06271
1211776000644	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776000645	active site
1211776000646	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1211776000647	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1211776000648	hinge region; other site
1211776000649	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
1211776000651	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1211776000652	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1211776000654	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
1211776000655	active site clefts [active]
1211776000656	zinc binding site [ion binding]; other site
1211776000657	dimer interface [polypeptide binding]; other site
1211776000658	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1211776000659	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1211776000661	Fe-S cluster assembly protein NifU; Region: NifU_proper; TIGR02000
1211776000662	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1211776000663	trimerization site [polypeptide binding]; other site
1211776000664	active site
1211776000665	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1211776000666	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1211776000667	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1211776000668	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1211776000669	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1211776000670	catalytic residue [active]
1211776000671	Hemerythrin; Region: Hemerythrin; cd12107
1211776000672	Fe binding site [ion binding]; other site
1211776000673	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1211776000674	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1211776000675	23S rRNA binding site [nucleotide binding]; other site
1211776000676	L21 binding site [polypeptide binding]; other site
1211776000677	L13 binding site [polypeptide binding]; other site
1211776000678	FIST C domain; Region: FIST_C; pfam10442
1211776000679	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776000680	dimer interface [polypeptide binding]; other site
1211776000681	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1211776000682	putative CheW interface [polypeptide binding]; other site
1211776000683	FIST N domain; Region: FIST; cl10701
1211776000684	Predicted signal transduction protein [Signal transduction mechanisms]; Region: COG1639
1211776000685	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776000686	metabolite-proton symporter; Region: 2A0106; TIGR00883
1211776000687	putative substrate translocation pore; other site
1211776000689	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1211776000690	trimer interface [polypeptide binding]; other site
1211776000691	dimer interface [polypeptide binding]; other site
1211776000692	putative active site [active]
1211776000693	Protein of unknown function (DUF493); Region: DUF493; pfam04359
1211776000694	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
1211776000695	putative catalytic site [active]
1211776000696	putative metal binding site [ion binding]; other site
1211776000697	putative phosphate binding site [ion binding]; other site
1211776000698	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
1211776000699	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
1211776000700	Sulfatase; Region: Sulfatase; pfam00884
1211776000702	Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]; Region: DgkA; COG0818
1211776000704	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
1211776000705	active site
1211776000706	substrate binding pocket [chemical binding]; other site
1211776000707	dimer interface [polypeptide binding]; other site
1211776000708	Bestrophin, RFP-TM, chloride channel; Region: Bestrophin; cl01544
1211776000710	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776000711	S-adenosylmethionine binding site [chemical binding]; other site
1211776000712	Cache domain; Region: Cache_1; pfam02743
1211776000713	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776000714	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776000715	dimer interface [polypeptide binding]; other site
1211776000716	putative CheW interface [polypeptide binding]; other site
1211776000718	zinc transporter ZupT; Provisional; Region: PRK04201
1211776000719	ZIP Zinc transporter; Region: Zip; pfam02535
1211776000721	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
1211776000722	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
1211776000723	molybdopterin cofactor binding site [chemical binding]; other site
1211776000724	substrate binding site [chemical binding]; other site
1211776000725	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
1211776000726	molybdopterin cofactor binding site; other site
1211776000727	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
1211776000728	Cytochrome c; Region: Cytochrom_C; cl11414
1211776000729	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1211776000731	Protein of unknown function (DUF2393); Region: DUF2393; pfam09624
1211776000733	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1211776000734	SPFH domain / Band 7 family; Region: Band_7; pfam01145
1211776000736	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1211776000737	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1211776000738	homodimer interface [polypeptide binding]; other site
1211776000739	substrate-cofactor binding pocket; other site
1211776000740	catalytic residue [active]
1211776000741	Uncharacterized protein, 4-oxalocrotonate tautomerase homolog [General function prediction only]; Region: COG1942
1211776000742	active site 1 [active]
1211776000743	dimer interface [polypeptide binding]; other site
1211776000744	hexamer interface [polypeptide binding]; other site
1211776000745	active site 2 [active]
1211776000746	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
1211776000747	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1211776000748	catalytic triad [active]
1211776000749	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases and ATP sulphurylases. The domain forms a apha/beta/apha fold which  binds to Adenosine group; Region: Alpha_ANH_like; cd01986
1211776000750	Ligand Binding Site [chemical binding]; other site
1211776000751	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1211776000752	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
1211776000753	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
1211776000754	active site
1211776000755	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1211776000756	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1211776000757	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase; pfam01078
1211776000758	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776000759	Walker A motif; other site
1211776000760	ATP binding site [chemical binding]; other site
1211776000761	Walker B motif; other site
1211776000762	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1211776000763	rod shape-determining protein MreB; Provisional; Region: PRK13927
1211776000764	MreB and similar proteins; Region: MreB_like; cd10225
1211776000765	nucleotide binding site [chemical binding]; other site
1211776000766	Mg binding site [ion binding]; other site
1211776000767	putative protofilament interaction site [polypeptide binding]; other site
1211776000768	RodZ interaction site [polypeptide binding]; other site
1211776000769	Cell shape-determining protein [Cell envelope biogenesis, outer membrane]; Region: MreC; COG1792
1211776000770	rod shape-determining protein MreC; Region: MreC; pfam04085
1211776000772	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1211776000773	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1211776000774	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1211776000775	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1211776000776	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1211776000777	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1211776000778	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
1211776000779	IMP binding site; other site
1211776000780	dimer interface [polypeptide binding]; other site
1211776000781	interdomain contacts; other site
1211776000782	partial ornithine binding site; other site
1211776000783	Telomere recombination; Region: Sua5_yciO_yrdC; cl00305
1211776000784	Transaldolase-like proteins from plants and bacteria; Region: Transaldolase_like; cd00955
1211776000785	putative active site [active]
1211776000786	transaldolase; Provisional; Region: PRK03903
1211776000787	catalytic residue [active]
1211776000788	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1211776000789	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1211776000790	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776000791	motif II; other site
1211776000792	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1211776000793	putative CheA interaction surface; other site
1211776000794	chemotaxis protein CheA; Provisional; Region: PRK10547
1211776000795	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1211776000796	putative binding surface; other site
1211776000797	active site
1211776000798	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1211776000799	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776000800	ATP binding site [chemical binding]; other site
1211776000801	Mg2+ binding site [ion binding]; other site
1211776000802	G-X-G motif; other site
1211776000803	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1211776000804	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1211776000805	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776000806	active site
1211776000807	phosphorylation site [posttranslational modification]
1211776000808	intermolecular recognition site; other site
1211776000809	dimerization interface [polypeptide binding]; other site
1211776000810	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1211776000811	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1211776000812	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776000813	active site
1211776000814	phosphorylation site [posttranslational modification]
1211776000815	intermolecular recognition site; other site
1211776000816	dimerization interface [polypeptide binding]; other site
1211776000817	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2908
1211776000818	active site
1211776000819	metal binding site [ion binding]; metal-binding site
1211776000820	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1211776000821	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1211776000822	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1211776000823	Lipid A disaccharide synthetase [Cell envelope biogenesis, outer membrane]; Region: LpxB; COG0763
1211776000824	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
1211776000825	Accessory colonization factor AcfC, contains ABC-type periplasmic domain [General function prediction only]; Region: AcfC; COG4588
1211776000826	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1211776000830	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
1211776000831	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1211776000832	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
1211776000833	ATP binding site [chemical binding]; other site
1211776000834	substrate interface [chemical binding]; other site
1211776000836	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1211776000837	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776000838	Coenzyme A binding pocket [chemical binding]; other site
1211776000839	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1211776000840	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1211776000841	tetramerization interface [polypeptide binding]; other site
1211776000842	active site
1211776000843	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1211776000844	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1211776000845	active site
1211776000846	ATP-binding site [chemical binding]; other site
1211776000847	pantoate-binding site; other site
1211776000848	HXXH motif; other site
1211776000849	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1211776000850	active site
1211776000851	oligomerization interface [polypeptide binding]; other site
1211776000852	metal binding site [ion binding]; metal-binding site
1211776000853	Beta-lactamase class D [Defense mechanisms]; Region: COG2602
1211776000854	ABC-type thiamine transport system, ATPase component [Coenzyme metabolism]; Region: ThiQ; COG3840
1211776000855	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776000856	Walker A/P-loop; other site
1211776000857	ATP binding site [chemical binding]; other site
1211776000858	Q-loop/lid; other site
1211776000859	ABC transporter signature motif; other site
1211776000860	Walker B; other site
1211776000861	D-loop; other site
1211776000862	H-loop/switch region; other site
1211776000863	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776000864	dimer interface [polypeptide binding]; other site
1211776000865	conserved gate region; other site
1211776000866	putative PBP binding loops; other site
1211776000867	ABC-ATPase subunit interface; other site
1211776000869	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1211776000870	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
1211776000871	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1211776000873	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
1211776000874	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776000875	S-adenosylmethionine binding site [chemical binding]; other site
1211776000876	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1211776000877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2830
1211776000878	7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism]; Region: BioF; COG0156
1211776000879	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1211776000880	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1211776000881	catalytic residue [active]
1211776000882	adenosylmethionine--8-amino-7-oxononanoate transaminase; Provisional; Region: PRK05964
1211776000883	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1211776000884	inhibitor-cofactor binding pocket; inhibition site
1211776000885	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776000886	catalytic residue [active]
1211776000887	Dethiobiotin synthetase [Coenzyme metabolism]; Region: BioD; COG0132
1211776000888	AAA domain; Region: AAA_26; pfam13500
1211776000889	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1211776000891	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1211776000893	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1211776000894	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1211776000895	5S rRNA interface [nucleotide binding]; other site
1211776000896	CTC domain interface [polypeptide binding]; other site
1211776000897	L16 interface [polypeptide binding]; other site
1211776000898	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1211776000899	putative active site [active]
1211776000900	catalytic residue [active]
1211776000901	Predicted permeases [General function prediction only]; Region: COG0795
1211776000902	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1211776000904	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1211776000905	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1211776000906	active site
1211776000907	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1211776000908	substrate binding site [chemical binding]; other site
1211776000909	catalytic residues [active]
1211776000910	dimer interface [polypeptide binding]; other site
1211776000911	Haloacid Dehalogenase Superfamily Class (subfamily) IIA; Region: HAD-SF-IIA; TIGR01460
1211776000912	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776000913	active site
1211776000914	motif I; other site
1211776000915	motif II; other site
1211776000916	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1211776000917	chorismate mutase domain of proteobacterial P-protein, clade 2; Region: CM_P2; TIGR01807
1211776000918	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1211776000919	Prephenate dehydratase; Region: PDT; pfam00800
1211776000920	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1211776000921	putative L-Phe binding site [chemical binding]; other site
1211776000922	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
1211776000923	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1211776000924	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776000925	homodimer interface [polypeptide binding]; other site
1211776000926	catalytic residue [active]
1211776000927	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1211776000928	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1211776000929	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1211776000931	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1211776000932	FliG C-terminal domain; Region: FliG_C; pfam01706
1211776000933	flagellar assembly protein H; Validated; Region: fliH; PRK06669
1211776000934	Flagellar assembly protein FliH; Region: FliH; pfam02108
1211776000935	Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]; Region: Dxs; COG1154
1211776000936	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1211776000937	TPP-binding site; other site
1211776000938	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1211776000939	PYR/PP interface [polypeptide binding]; other site
1211776000940	dimer interface [polypeptide binding]; other site
1211776000941	TPP binding site [chemical binding]; other site
1211776000942	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1211776000943	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1211776000944	metal binding site 2 [ion binding]; metal-binding site
1211776000945	putative DNA binding helix; other site
1211776000946	metal binding site 1 [ion binding]; metal-binding site
1211776000947	structural Zn2+ binding site [ion binding]; other site
1211776000948	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
1211776000949	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776000950	S-adenosylmethionine binding site [chemical binding]; other site
1211776000951	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
1211776000952	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1211776000953	generic binding surface II; other site
1211776000954	generic binding surface I; other site
1211776000955	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
1211776000956	homodimer interface [polypeptide binding]; other site
1211776000957	substrate-cofactor binding pocket; other site
1211776000958	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776000959	catalytic residue [active]
1211776000960	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
1211776000961	homotrimer interaction site [polypeptide binding]; other site
1211776000962	putative active site [active]
1211776000963	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1211776000964	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1211776000965	dimer interface [polypeptide binding]; other site
1211776000966	active site
1211776000967	CoA binding pocket [chemical binding]; other site
1211776000968	putative phosphate acyltransferase; Provisional; Region: PRK05331
1211776000969	Ribosomal protein L32 [Translation, ribosomal structure and biogenesis]; Region: RpmF; COG0333
1211776000970	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
1211776000971	active site
1211776000972	multimer interface [polypeptide binding]; other site
1211776000973	Ferredoxin [Energy production and conversion]; Region: COG1146
1211776000974	4Fe-4S binding domain; Region: Fer4; cl02805
1211776000975	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1211776000976	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1211776000977	dimer interface [polypeptide binding]; other site
1211776000978	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1211776000979	catalytic triad [active]
1211776000980	peroxidatic and resolving cysteines [active]
1211776000981	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1211776000982	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
1211776000984	flagellar motor protein MotB; Reviewed; Region: motB; PRK08457
1211776000985	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1211776000986	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1211776000987	ligand binding site [chemical binding]; other site
1211776000989	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1211776000990	flagellar motor protein MotA; Validated; Region: PRK08456
1211776000992	DNA polymerase I; Provisional; Region: PRK05755
1211776000993	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1211776000994	active site
1211776000995	metal binding site 1 [ion binding]; metal-binding site
1211776000996	putative 5' ssDNA interaction site; other site
1211776000997	metal binding site 3; metal-binding site
1211776000998	metal binding site 2 [ion binding]; metal-binding site
1211776000999	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1211776001000	putative DNA binding site [nucleotide binding]; other site
1211776001001	putative metal binding site [ion binding]; other site
1211776001002	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
1211776001003	active site
1211776001004	catalytic site [active]
1211776001005	substrate binding site [chemical binding]; other site
1211776001006	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1211776001007	active site
1211776001008	DNA binding site [nucleotide binding]
1211776001009	catalytic site [active]
1211776001010	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776001011	metabolite-proton symporter; Region: 2A0106; TIGR00883
1211776001012	putative substrate translocation pore; other site
1211776001014	nuc_hydro_CjNH. Nucleoside hydrolases similar to Campylobacter jejuni nucleoside hydrolase.  This group contains eukaryotic and bacterial proteins similar to C. jejuni nucleoside hydrolase. Nucleoside hydrolases cleave the N-glycosidic bond in...; Region: nuc_hydro_CjNH; cd02654
1211776001015	active site
1211776001016	Predicted membrane protein [Function unknown]; Region: COG1238
1211776001018	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1211776001019	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1211776001020	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1211776001021	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1211776001022	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1211776001024	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1211776001025	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1211776001026	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1211776001027	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1211776001028	glutamine binding [chemical binding]; other site
1211776001029	catalytic triad [active]
1211776001030	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1211776001031	anthranilate phosphoribosyltransferase; Region: trpD; TIGR01245
1211776001032	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1211776001033	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1211776001034	active site
1211776001035	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1211776001036	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1211776001037	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776001038	catalytic residue [active]
1211776001039	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1211776001040	substrate binding site [chemical binding]; other site
1211776001041	active site
1211776001042	catalytic residues [active]
1211776001043	heterodimer interface [polypeptide binding]; other site
1211776001044	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1211776001045	flagellar motor switch protein; Validated; Region: PRK08433
1211776001047	Exopolyphosphatase [Nucleotide transport and metabolism / Inorganic ion transport and metabolism]; Region: GppA; COG0248
1211776001048	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1211776001049	benzoyl-CoA oxygenase/reductase, BoxA protein; Region: benzo_boxA; TIGR03224
1211776001050	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1211776001051	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776001052	active site
1211776001053	phosphorylation site [posttranslational modification]
1211776001054	intermolecular recognition site; other site
1211776001055	dimerization interface [polypeptide binding]; other site
1211776001056	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1211776001057	DNA binding site [nucleotide binding]
1211776001058	Dihydroneopterin aldolase [Coenzyme metabolism]; Region: FolB; COG1539
1211776001059	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
1211776001061	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
1211776001062	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14324
1211776001063	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1211776001064	active site
1211776001065	substrate binding site [chemical binding]; other site
1211776001066	metal binding site [ion binding]; metal-binding site
1211776001067	Lipoprotein signal peptidase [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: LspA; COG0597
1211776001068	lipoprotein signal peptidase; Provisional; Region: PRK14787
1211776001070	Uncharacterized protein family (UPF0093); Region: UPF0093; pfam03653
1211776001072	coproporphyrinogen III oxidase; Provisional; Region: PRK08629
1211776001073	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1211776001074	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1211776001075	Protein export membrane protein; Region: SecD_SecF; cl14618
1211776001077	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1211776001078	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1211776001079	HlyD family secretion protein; Region: HlyD_3; pfam13437
1211776001080	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1211776001081	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1211776001082	cytochrome c oxidase accessory protein FixG; Region: ccoG_rdxA_fixG; TIGR02745
1211776001083	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1211776001084	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1211776001085	Ubp3 associated protein Bre5; Region: Bre5; pfam11614
1211776001087	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1211776001088	hypothetical protein; Provisional; Region: PRK04081
1211776001090	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
1211776001091	2-hydroxyacid dehydrogenase; Provisional; Region: PRK08410
1211776001092	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1211776001093	putative ligand binding site [chemical binding]; other site
1211776001094	putative NAD binding site [chemical binding]; other site
1211776001095	catalytic site [active]
1211776001096	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1666
1211776001097	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
1211776001098	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1211776001099	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776001100	Walker A motif; other site
1211776001101	ATP binding site [chemical binding]; other site
1211776001102	Walker B motif; other site
1211776001103	arginine finger; other site
1211776001104	Predicted membrane protein [Function unknown]; Region: COG2717
1211776001106	TMAO/DMSO reductase; Reviewed; Region: PRK05363
1211776001107	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
1211776001108	Moco binding site; other site
1211776001109	metal coordination site [ion binding]; other site
1211776001110	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1211776001111	active site
1211776001112	dimer interface [polypeptide binding]; other site
1211776001113	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1211776001114	putative RNA binding site [nucleotide binding]; other site
1211776001115	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1211776001116	homopentamer interface [polypeptide binding]; other site
1211776001117	active site
1211776001118	2-dehydro-3-deoxyphosphooctonate aldolase; Provisional; Region: PRK05198
1211776001119	EamA-like transporter family; Region: EamA; pfam00892
1211776001120	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1211776001122	GTP-binding protein Der; Reviewed; Region: PRK00093
1211776001123	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1211776001124	G1 box; other site
1211776001125	GTP/Mg2+ binding site [chemical binding]; other site
1211776001126	Switch I region; other site
1211776001127	G2 box; other site
1211776001128	Switch II region; other site
1211776001129	G3 box; other site
1211776001130	G4 box; other site
1211776001131	G5 box; other site
1211776001132	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1211776001133	GTP/Mg2+ binding site [chemical binding]; other site
1211776001134	Switch I region; other site
1211776001135	G2 box; other site
1211776001136	G3 box; other site
1211776001137	Switch II region; other site
1211776001138	G4 box; other site
1211776001139	G5 box; other site
1211776001140	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
1211776001141	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1211776001142	ADP binding site [chemical binding]; other site
1211776001143	magnesium binding site [ion binding]; other site
1211776001144	putative shikimate binding site; other site
1211776001145	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1211776001146	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1211776001147	active site
1211776001148	HIGH motif; other site
1211776001149	dimer interface [polypeptide binding]; other site
1211776001150	KMSKS motif; other site
1211776001151	seryl-tRNA synthetase; Provisional; Region: PRK05431
1211776001152	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1211776001153	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1211776001154	dimer interface [polypeptide binding]; other site
1211776001155	active site
1211776001156	motif 1; other site
1211776001157	motif 2; other site
1211776001158	motif 3; other site
1211776001159	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1211776001160	binding surface
1211776001161	TPR motif; other site
1211776001162	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1211776001163	TPR motif; other site
1211776001165	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1211776001166	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1211776001167	domain interfaces; other site
1211776001168	active site
1211776001169	Predicted dehydrogenase [General function prediction only]; Region: COG0579
1211776001170	Malate:quinone oxidoreductase (Mqo); Region: Mqo; cl17341
1211776001171	pantothenate kinase; Reviewed; Region: PRK13333
1211776001172	PQQ-like domain; Region: PQQ_2; pfam13360
1211776001174	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1211776001175	Uncharacterized membrane protein, required for colicin V production [General function prediction only]; Region: CvpA; COG1286
1211776001176	Colicin V production protein; Region: Colicin_V; pfam02674
1211776001178	ferric uptake regulator; Provisional; Region: fur; PRK09462
1211776001179	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1211776001180	metal binding site 2 [ion binding]; metal-binding site
1211776001181	putative DNA binding helix; other site
1211776001182	metal binding site 1 [ion binding]; metal-binding site
1211776001183	dimer interface [polypeptide binding]; other site
1211776001184	structural Zn2+ binding site [ion binding]; other site
1211776001185	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1211776001186	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1211776001187	dimer interface [polypeptide binding]; other site
1211776001188	putative anticodon binding site; other site
1211776001189	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1211776001190	motif 1; other site
1211776001191	active site
1211776001192	motif 2; other site
1211776001193	motif 3; other site
1211776001194	serine hydroxymethyltransferase; Reviewed; Region: PRK13034
1211776001195	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1211776001196	dimer interface [polypeptide binding]; other site
1211776001197	active site
1211776001198	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1211776001199	folate binding site [chemical binding]; other site
1211776001200	Domain of unknown function (DUF1882); Region: DUF1882; pfam08966
1211776001201	Sporulation related domain; Region: SPOR; pfam05036
1211776001203	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1211776001204	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1211776001205	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1211776001206	shikimate binding site; other site
1211776001207	NAD(P) binding site [chemical binding]; other site
1211776001209	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1211776001211	fumarate reductase cytochrome b-556 subunit; Provisional; Region: PRK13553
1211776001212	Quinol:fumarate reductase (QFR) Type B subfamily, transmembrane subunit;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinone...; Region: QFR_TypeB_TM; cd00581
1211776001213	Iron-sulfur protein interface; other site
1211776001214	proximal heme binding site [chemical binding]; other site
1211776001215	distal heme binding site [chemical binding]; other site
1211776001216	dimer interface [polypeptide binding]; other site
1211776001218	fumarate reductase flavoprotein subunit; Provisional; Region: PRK08626
1211776001219	L-aspartate oxidase; Provisional; Region: PRK06175
1211776001220	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1211776001221	fumarate reductase iron-sulfur subunit; Provisional; Region: frdB; PRK13552
1211776001222	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1211776001223	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1211776001224	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1211776001225	Dynamin family; Region: Dynamin_N; pfam00350
1211776001226	G1 box; other site
1211776001227	GTP/Mg2+ binding site [chemical binding]; other site
1211776001228	G2 box; other site
1211776001229	Switch I region; other site
1211776001230	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1211776001231	G3 box; other site
1211776001232	Switch II region; other site
1211776001233	GTP/Mg2+ binding site [chemical binding]; other site
1211776001234	G4 box; other site
1211776001235	G5 box; other site
1211776001236	Dynamin-like protein including dynamins, mitofusins, and guanylate-binding proteins; Region: DLP_2; cd09912
1211776001237	Dynamin family; Region: Dynamin_N; pfam00350
1211776001238	G1 box; other site
1211776001239	GTP/Mg2+ binding site [chemical binding]; other site
1211776001240	G2 box; other site
1211776001241	Switch I region; other site
1211776001242	G3 box; other site
1211776001243	Switch II region; other site
1211776001244	G4 box; other site
1211776001245	G5 box; other site
1211776001246	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
1211776001247	Sel1-like repeats; Region: SEL1; smart00671
1211776001248	Sel1-like repeats; Region: SEL1; smart00671
1211776001249	Gluconate 2-dehydrogenase subunit 3; Region: Gluconate_2-dh3; pfam13618
1211776001251	Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism]; Region: BetA; COG2303
1211776001252	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1211776001253	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
1211776001254	SprA-related family; Region: SprA-related; pfam12118
1211776001255	Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only]; Region: Hit; COG0537
1211776001256	HIT family signature motif; other site
1211776001257	catalytic residue [active]
1211776001258	Uncharacterized conserved protein [Function unknown]; Region: COG2353
1211776001260	Transposase; Region: HTH_Tnp_1; cl17663
1211776001261	Superinfection immunity protein; Region: Imm_superinfect; pfam14373
1211776001263	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
1211776001264	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1211776001265	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1211776001266	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1211776001267	ABC transporter; Region: ABC_tran_2; pfam12848
1211776001268	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1211776001269	S-layer like family, C-terminal region; Region: S_layer_C; pfam05124
1211776001270	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1211776001271	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1211776001274	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03815
1211776001275	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1211776001276	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1211776001277	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1211776001278	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1211776001279	Mg++ binding site [ion binding]; other site
1211776001280	putative catalytic motif [active]
1211776001281	putative substrate binding site [chemical binding]; other site
1211776001283	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1211776001284	phosphoglyceromutase; Provisional; Region: PRK05434
1211776001285	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1211776001286	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
1211776001287	NAD(P) binding site [chemical binding]; other site
1211776001288	active site
1211776001289	Uncharacterized conserved protein [Function unknown]; Region: COG5015
1211776001290	L-aspartate oxidase; Provisional; Region: PRK06175
1211776001291	succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative/mitochondrial subgroup; Region: sdhA_frdA_Gneg; TIGR01812
1211776001292	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1211776001293	Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit [Energy production and conversion]; Region: FrdB; COG0479
1211776001294	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1211776001295	Heterodisulfide reductase, subunit B [Energy production and conversion]; Region: HdrB; COG2048
1211776001296	Cysteine-rich domain; Region: CCG; pfam02754
1211776001297	Cysteine-rich domain; Region: CCG; pfam02754
1211776001298	Putative transcription activator [Transcription]; Region: TenA; COG0819
1211776001299	acyl carrier protein; Provisional; Region: acpP; PRK00982
1211776001300	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK08439
1211776001301	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1211776001302	dimer interface [polypeptide binding]; other site
1211776001303	active site
1211776001304	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1211776001305	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1211776001307	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1211776001308	dimer interface [polypeptide binding]; other site
1211776001309	ADP-ribose binding site [chemical binding]; other site
1211776001310	active site
1211776001311	nudix motif; other site
1211776001312	metal binding site [ion binding]; metal-binding site
1211776001313	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776001314	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776001315	dimer interface [polypeptide binding]; other site
1211776001316	putative CheW interface [polypeptide binding]; other site
1211776001317	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1211776001318	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2841
1211776001319	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1211776001320	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1211776001321	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
1211776001322	substrate binding site [chemical binding]; other site
1211776001323	hexamer interface [polypeptide binding]; other site
1211776001324	metal binding site [ion binding]; metal-binding site
1211776001325	DNA polymerase III subunit epsilon; Provisional; Region: PRK08517
1211776001326	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1211776001327	active site
1211776001328	catalytic site [active]
1211776001329	substrate binding site [chemical binding]; other site
1211776001330	thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352
1211776001331	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
1211776001334	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: DUF374; Region: LPLAT_DUF374-like; cd07983
1211776001335	putative acyl-acceptor binding pocket; other site
1211776001337	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1211776001338	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14339
1211776001339	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776001340	FeS/SAM binding site; other site
1211776001341	TRAM domain; Region: TRAM; pfam01938
1211776001342	transcription elongation factor NusA; Provisional; Region: nusA; PRK12328
1211776001343	NusA N-terminal domain; Region: NusA_N; pfam08529
1211776001344	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1211776001345	RNA binding site [nucleotide binding]; other site
1211776001346	homodimer interface [polypeptide binding]; other site
1211776001347	NusA-like KH domain; Region: KH_5; pfam13184
1211776001348	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1211776001349	G-X-X-G motif; other site
1211776001350	H+ Antiporter protein; Region: 2A0121; TIGR00900
1211776001352	hypothetical protein; Provisional; Region: PRK08445
1211776001353	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776001354	FeS/SAM binding site; other site
1211776001355	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1211776001356	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1211776001357	RecG-like helicase [DNA replication, recombination, and repair / Transcription]; Region: RecG; COG1200
1211776001358	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1211776001359	generic binding surface II; other site
1211776001360	ssDNA binding site; other site
1211776001361	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1211776001362	ATP binding site [chemical binding]; other site
1211776001363	putative Mg++ binding site [ion binding]; other site
1211776001364	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1211776001365	nucleotide binding region [chemical binding]; other site
1211776001366	ATP-binding site [chemical binding]; other site
1211776001367	Truncated hemoglobins (trHbs) are a family of oxygen-binding heme proteins found in cyanobacteria, eubacteria, unicellular eukaryotes, and plants. The truncated hemoglobins have a characteristic two-over-two alpha helical folding pattern that is distinct...; Region: Trunc_globin; cd00454
1211776001368	apolar tunnel; other site
1211776001369	heme binding site [chemical binding]; other site
1211776001370	dimerization interface [polypeptide binding]; other site
1211776001371	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1211776001372	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1211776001373	ligand binding site [chemical binding]; other site
1211776001374	flexible hinge region; other site
1211776001375	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1211776001376	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776001377	dimer interface [polypeptide binding]; other site
1211776001378	conserved gate region; other site
1211776001379	putative PBP binding loops; other site
1211776001380	ABC-ATPase subunit interface; other site
1211776001382	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776001383	dimer interface [polypeptide binding]; other site
1211776001384	conserved gate region; other site
1211776001385	putative PBP binding loops; other site
1211776001386	ABC-ATPase subunit interface; other site
1211776001388	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1211776001389	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1211776001390	Walker A/P-loop; other site
1211776001391	ATP binding site [chemical binding]; other site
1211776001392	Q-loop/lid; other site
1211776001393	ABC transporter signature motif; other site
1211776001394	Walker B; other site
1211776001395	D-loop; other site
1211776001396	H-loop/switch region; other site
1211776001397	elongation factor Tu; Reviewed; Region: PRK00049
1211776001398	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1211776001399	G1 box; other site
1211776001400	GEF interaction site [polypeptide binding]; other site
1211776001401	GTP/Mg2+ binding site [chemical binding]; other site
1211776001402	Switch I region; other site
1211776001403	G2 box; other site
1211776001404	G3 box; other site
1211776001405	Switch II region; other site
1211776001406	G4 box; other site
1211776001407	G5 box; other site
1211776001408	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1211776001409	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1211776001410	Antibiotic Binding Site [chemical binding]; other site
1211776001411	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
1211776001412	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1211776001414	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1211776001415	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1211776001416	putative homodimer interface [polypeptide binding]; other site
1211776001417	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1211776001418	heterodimer interface [polypeptide binding]; other site
1211776001419	homodimer interface [polypeptide binding]; other site
1211776001420	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1211776001421	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1211776001422	23S rRNA interface [nucleotide binding]; other site
1211776001423	L7/L12 interface [polypeptide binding]; other site
1211776001424	putative thiostrepton binding site; other site
1211776001425	L25 interface [polypeptide binding]; other site
1211776001426	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1211776001427	mRNA/rRNA interface [nucleotide binding]; other site
1211776001428	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1211776001429	23S rRNA interface [nucleotide binding]; other site
1211776001430	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1211776001431	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1211776001432	L11 interface [polypeptide binding]; other site
1211776001433	putative EF-Tu interaction site [polypeptide binding]; other site
1211776001434	putative EF-G interaction site [polypeptide binding]; other site
1211776001435	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1211776001436	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1211776001437	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1211776001438	RPB11 interaction site [polypeptide binding]; other site
1211776001439	RPB12 interaction site [polypeptide binding]; other site
1211776001440	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1211776001441	RPB3 interaction site [polypeptide binding]; other site
1211776001442	RPB1 interaction site [polypeptide binding]; other site
1211776001443	RPB11 interaction site [polypeptide binding]; other site
1211776001444	RPB10 interaction site [polypeptide binding]; other site
1211776001445	DNA-directed RNA polymerase, beta' subunit/160 kD subunit [Transcription]; Region: RpoC; COG0086
1211776001446	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1211776001447	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1211776001448	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1211776001449	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1211776001450	RNA polymerase Rpb1, domain 5; Region: RNA_pol_Rpb1_5; pfam04998
1211776001451	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1211776001452	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
1211776001453	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
1211776001454	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1211776001455	DNA binding site [nucleotide binding]
1211776001456	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1211776001457	Transcriptional regulator [Transcription]; Region: IclR; COG1414
1211776001458	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1211776001459	putative DNA binding site [nucleotide binding]; other site
1211776001460	putative Zn2+ binding site [ion binding]; other site
1211776001461	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1211776001462	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
1211776001463	inhibitor site; inhibition site
1211776001464	active site
1211776001465	dimer interface [polypeptide binding]; other site
1211776001466	catalytic residue [active]
1211776001467	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
1211776001468	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
1211776001469	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776001470	putative substrate translocation pore; other site
1211776001472	short chain dehydrogenase; Provisional; Region: PRK08628
1211776001473	classical (c) SDRs; Region: SDR_c; cd05233
1211776001474	NAD(P) binding site [chemical binding]; other site
1211776001475	active site
1211776001476	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
1211776001477	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776001478	putative substrate translocation pore; other site
1211776001479	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776001481	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1211776001482	Amidohydrolase; Region: Amidohydro_2; pfam04909
1211776001483	Uncharacterized conserved protein [Function unknown]; Region: COG3254
1211776001484	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1211776001485	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
1211776001486	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1211776001487	NAD binding site [chemical binding]; other site
1211776001488	catalytic residues [active]
1211776001489	substrate binding site [chemical binding]; other site
1211776001491	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1211776001492	S17 interaction site [polypeptide binding]; other site
1211776001493	S8 interaction site; other site
1211776001494	16S rRNA interaction site [nucleotide binding]; other site
1211776001495	streptomycin interaction site [chemical binding]; other site
1211776001496	23S rRNA interaction site [nucleotide binding]; other site
1211776001497	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1211776001498	30S ribosomal protein S7; Validated; Region: PRK05302
1211776001499	elongation factor G; Reviewed; Region: PRK00007
1211776001500	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1211776001501	G1 box; other site
1211776001502	putative GEF interaction site [polypeptide binding]; other site
1211776001503	GTP/Mg2+ binding site [chemical binding]; other site
1211776001504	Switch I region; other site
1211776001505	G2 box; other site
1211776001506	G3 box; other site
1211776001507	Switch II region; other site
1211776001508	G4 box; other site
1211776001509	G5 box; other site
1211776001510	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1211776001511	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1211776001512	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1211776001513	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1211776001514	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776001515	S-adenosylmethionine binding site [chemical binding]; other site
1211776001516	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
1211776001517	putative PEP-CTERM system TPR-repeat lipoprotein; Region: PEP_TPR_lipo; TIGR02917
1211776001519	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1211776001520	active site
1211776001521	substrate (anthranilate) binding pocket [chemical binding]; other site
1211776001522	product (indole) binding pocket [chemical binding]; other site
1211776001523	ribulose/triose binding site [chemical binding]; other site
1211776001524	phosphate binding site [ion binding]; other site
1211776001525	FHIT (fragile histidine family): FHIT proteins, related to the HIT family carry a motif HxHxH/Qxx (x, is a hydrophobic amino acid), On the basis of sequence, substrate specificity, structure, evolution and mechanism, HIT proteins are classified into...; Region: FHIT; cd01275
1211776001526	nucleotide binding site/active site [active]
1211776001527	HIT family signature motif; other site
1211776001528	catalytic residue [active]
1211776001529	Predicted ATPase [General function prediction only]; Region: COG2603
1211776001530	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1211776001531	active site residue [active]
1211776001535	ferrochelatase; Reviewed; Region: hemH; PRK00035
1211776001536	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
1211776001537	C-terminal domain interface [polypeptide binding]; other site
1211776001538	active site
1211776001539	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
1211776001540	active site
1211776001541	N-terminal domain interface [polypeptide binding]; other site
1211776001542	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1211776001543	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1211776001544	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1211776001545	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1211776001546	inhibitor-cofactor binding pocket; inhibition site
1211776001547	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776001548	catalytic residue [active]
1211776001549	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1211776001550	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1211776001551	motif 1; other site
1211776001552	active site
1211776001553	motif 2; other site
1211776001554	motif 3; other site
1211776001555	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1211776001556	DHHA1 domain; Region: DHHA1; pfam02272
1211776001557	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1211776001558	Maf-like protein; Region: Maf; pfam02545
1211776001559	active site
1211776001560	dimer interface [polypeptide binding]; other site
1211776001561	Transglycosylase; Region: Transgly; pfam00912
1211776001562	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1211776001563	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1211776001565	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1211776001566	Clp amino terminal domain; Region: Clp_N; pfam02861
1211776001567	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776001568	Walker A motif; other site
1211776001569	ATP binding site [chemical binding]; other site
1211776001570	Walker B motif; other site
1211776001571	arginine finger; other site
1211776001572	Protein of unknown function (DUF972); Region: DUF972; pfam06156
1211776001573	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776001574	Walker A motif; other site
1211776001575	ATP binding site [chemical binding]; other site
1211776001576	Walker B motif; other site
1211776001577	arginine finger; other site
1211776001578	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1211776001579	Uncharacterized family 1; belongs to a superfamily containing the transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156; Region: CsoR-like_DUF156_1; cd10158
1211776001580	putative homodimer interface [polypeptide binding]; other site
1211776001581	putative homotetramer interface [polypeptide binding]; other site
1211776001582	putative metal binding site [ion binding]; other site
1211776001583	putative homodimer-homodimer interface [polypeptide binding]; other site
1211776001584	putative allosteric switch controlling residues; other site
1211776001585	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1211776001586	C-terminal peptidase (prc); Region: prc; TIGR00225
1211776001587	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1211776001588	protein binding site [polypeptide binding]; other site
1211776001589	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1211776001590	Catalytic dyad [active]
1211776001592	phosphoribosylaminoimidazole-succinocarboxamide synthase; Reviewed; Region: PRK09362
1211776001593	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
1211776001594	ATP binding site [chemical binding]; other site
1211776001595	active site
1211776001596	substrate binding site [chemical binding]; other site
1211776001597	Phosphoribosylformylglycinamidine (FGAM) synthase; Region: PurS; pfam02700
1211776001598	phosphoribosylformylglycinamidine synthase I; Provisional; Region: PRK03619
1211776001599	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
1211776001600	putative active site [active]
1211776001601	catalytic triad [active]
1211776001603	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1211776001604	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1211776001605	putative acyl-acceptor binding pocket; other site
1211776001607	Integral membrane protein possibly involved in chromosome condensation [Cell division and chromosome partitioning]; Region: CrcB; COG0239
1211776001609	heat shock protein 90; Provisional; Region: PRK05218
1211776001610	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776001611	ATP binding site [chemical binding]; other site
1211776001612	Mg2+ binding site [ion binding]; other site
1211776001613	G-X-G motif; other site
1211776001614	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1211776001615	active site residue [active]
1211776001617	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1211776001618	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1211776001620	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1211776001622	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1211776001623	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1211776001624	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1211776001626	flagellar hook-basal body protein FliE; Reviewed; Region: fliE; PRK03907
1211776001627	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1211776001628	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1211776001629	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1211776001630	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1211776001631	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1211776001632	YceG-like family; Region: YceG; pfam02618
1211776001633	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1211776001634	dimerization interface [polypeptide binding]; other site
1211776001636	Protein of unknown function; Region: DUF3971; pfam13116
1211776001637	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1211776001638	AsmA-like C-terminal region; Region: AsmA_1; pfam13109
1211776001640	Monomeric isocitrate dehydrogenase [Energy production and conversion]; Region: Icd; COG2838
1211776001641	Monomeric isocitrate dehydrogenase; Region: IDH; cl15383
1211776001642	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
1211776001643	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
1211776001644	NAD(P) binding site [chemical binding]; other site
1211776001645	LDH/MDH dimer interface [polypeptide binding]; other site
1211776001646	substrate binding site [chemical binding]; other site
1211776001647	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
1211776001648	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
1211776001649	CoA-ligase; Region: Ligase_CoA; pfam00549
1211776001650	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
1211776001651	CoA binding domain; Region: CoA_binding; smart00881
1211776001652	CoA-ligase; Region: Ligase_CoA; pfam00549
1211776001653	2-oxoglutarate-acceptor oxidoreductase subunit OorD; Reviewed; Region: oorD; PRK09626
1211776001654	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1211776001655	2-oxoglutarate-acceptor oxidoreductase subunit OorA; Reviewed; Region: oorA; PRK09627
1211776001656	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1211776001657	dimer interface [polypeptide binding]; other site
1211776001658	PYR/PP interface [polypeptide binding]; other site
1211776001659	TPP binding site [chemical binding]; other site
1211776001660	substrate binding site [chemical binding]; other site
1211776001661	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1211776001662	2-oxoglutarate-acceptor oxidoreductase subunit OorB; Reviewed; Region: oorB; PRK09628
1211776001663	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1211776001664	TPP-binding site [chemical binding]; other site
1211776001665	2-oxoglutarate-acceptor oxidoreductase subunit OorC; Reviewed; Region: oorC; PRK08441
1211776001666	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1211776001667	Domain of unknown function (DUF2018); Region: DUF2018; pfam09442
1211776001668	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1211776001669	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1211776001670	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1211776001671	substrate binding pocket [chemical binding]; other site
1211776001672	chain length determination region; other site
1211776001673	substrate-Mg2+ binding site; other site
1211776001674	catalytic residues [active]
1211776001675	aspartate-rich region 1; other site
1211776001676	active site lid residues [active]
1211776001677	aspartate-rich region 2; other site
1211776001678	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1211776001679	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1211776001680	tRNA; other site
1211776001681	putative tRNA binding site [nucleotide binding]; other site
1211776001682	putative NADP binding site [chemical binding]; other site
1211776001683	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1211776001684	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1211776001685	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1211776001686	dimer interface [polypeptide binding]; other site
1211776001687	motif 1; other site
1211776001688	active site
1211776001689	motif 2; other site
1211776001690	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1211776001691	putative deacylase active site [active]
1211776001692	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1211776001693	active site
1211776001694	motif 3; other site
1211776001695	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1211776001696	anticodon binding site; other site
1211776001698	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1211776001699	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
1211776001700	domain interfaces; other site
1211776001701	active site
1211776001702	menaquinone biosynthesis decarboxylase, SCO4490 family; Region: mena_SCO4490; TIGR03701
1211776001703	flagellar protein FlaG; Provisional; Region: PRK08452
1211776001704	flagellar capping protein; Provisional; Region: PRK12765
1211776001705	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1211776001706	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1211776001707	flagellar protein FliS; Validated; Region: fliS; PRK05685
1211776001708	elongation factor P; Validated; Region: PRK00529
1211776001709	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1211776001710	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1211776001711	RNA binding site [nucleotide binding]; other site
1211776001712	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1211776001713	RNA binding site [nucleotide binding]; other site
1211776001714	Predicted membrane protein [Function unknown]; Region: COG3819
1211776001716	Predicted membrane protein [Function unknown]; Region: COG3817
1211776001717	Protein of unknown function (DUF979); Region: DUF979; pfam06166
1211776001719	Protein of unknown function (DUF2891); Region: DUF2891; pfam11199
1211776001720	Dicarboxylate carrier protein MatC N-terminus; Region: MatC_N; pfam07158
1211776001721	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
1211776001722	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1211776001724	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1211776001725	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1211776001726	active site
1211776001727	Predicted membrane protein [Function unknown]; Region: COG1289
1211776001728	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
1211776001730	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1211776001731	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1211776001732	putative catalytic cysteine [active]
1211776001733	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1211776001734	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1211776001735	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1211776001736	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1211776001737	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1211776001739	Protein of unknown function (DUF2860); Region: DUF2860; pfam11059
1211776001740	replicative DNA helicase; Provisional; Region: PRK08506
1211776001741	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1211776001742	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1211776001743	Walker A motif; other site
1211776001744	ATP binding site [chemical binding]; other site
1211776001745	Walker B motif; other site
1211776001746	DNA binding loops [nucleotide binding]
1211776001750	Predicted transcriptional regulator [Transcription]; Region: COG2378
1211776001751	HTH domain; Region: HTH_11; pfam08279
1211776001752	WYL domain; Region: WYL; pfam13280
1211776001753	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09314
1211776001754	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1211776001755	GTP cyclohydrolase II [Coenzyme metabolism]; Region: RibA; COG0807
1211776001756	Uncharacterized conserved protein [Function unknown]; Region: COG1610
1211776001757	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK08527
1211776001758	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1211776001759	PYR/PP interface [polypeptide binding]; other site
1211776001760	dimer interface [polypeptide binding]; other site
1211776001761	TPP binding site [chemical binding]; other site
1211776001762	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1211776001763	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1211776001764	TPP-binding site [chemical binding]; other site
1211776001765	dimer interface [polypeptide binding]; other site
1211776001766	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1211776001767	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1211776001768	putative valine binding site [chemical binding]; other site
1211776001769	dimer interface [polypeptide binding]; other site
1211776001770	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1211776001771	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
1211776001772	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
1211776001773	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
1211776001774	trimer interface [polypeptide binding]; other site
1211776001775	active site
1211776001776	UDP-GlcNAc binding site [chemical binding]; other site
1211776001777	lipid binding site [chemical binding]; lipid-binding site
1211776001778	Queuosine biosynthesis protein; Region: Queuosine_synth; pfam02547
1211776001779	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1211776001780	Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion]; Region: TatC; COG0805
1211776001782	sec-independent translocase; Provisional; Region: PRK04098
1211776001783	coproporphyrinogen III oxidase; Provisional; Region: PRK08446
1211776001784	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
1211776001785	putative active site [active]
1211776001786	Ap4A binding site [chemical binding]; other site
1211776001787	nudix motif; other site
1211776001788	putative metal binding site [ion binding]; other site
1211776001789	aspartate kinase; Reviewed; Region: PRK06635
1211776001790	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1211776001791	putative nucleotide binding site [chemical binding]; other site
1211776001792	putative catalytic residues [active]
1211776001793	putative Mg ion binding site [ion binding]; other site
1211776001794	putative aspartate binding site [chemical binding]; other site
1211776001795	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1211776001796	putative allosteric regulatory site; other site
1211776001797	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1211776001798	DNA replication regulator; Region: HobA; pfam12163
1211776001799	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1211776001800	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
1211776001801	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1211776001802	substrate binding pocket [chemical binding]; other site
1211776001803	dimer interface [polypeptide binding]; other site
1211776001804	inhibitor binding site; inhibition site
1211776001805	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1211776001806	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1211776001807	nucleotide binding pocket [chemical binding]; other site
1211776001808	K-X-D-G motif; other site
1211776001809	catalytic site [active]
1211776001810	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1211776001811	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1211776001812	Dimer interface [polypeptide binding]; other site
1211776001813	BRCT sequence motif; other site
1211776001815	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1211776001816	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1211776001817	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1211776001818	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1211776001819	active site
1211776001820	nucleotide binding site [chemical binding]; other site
1211776001821	HIGH motif; other site
1211776001822	KMSKS motif; other site
1211776001823	Riboflavin kinase; Region: Flavokinase; pfam01687
1211776001824	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1211776001825	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776001826	S-adenosylmethionine binding site [chemical binding]; other site
1211776001827	Predicted membrane protein [Function unknown]; Region: COG2860
1211776001828	UPF0126 domain; Region: UPF0126; pfam03458
1211776001829	UPF0126 domain; Region: UPF0126; pfam03458
1211776001831	DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism]; Region: NUC1; COG1864
1211776001832	DNA/RNA non-specific endonuclease; Region: Endonuclease_NS; smart00892
1211776001833	active site
1211776001834	substrate binding site [chemical binding]; other site
1211776001835	Mg2+ binding site [ion binding]; other site
1211776001836	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1211776001837	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1211776001838	minor groove reading motif; other site
1211776001839	helix-hairpin-helix signature motif; other site
1211776001840	substrate binding pocket [chemical binding]; other site
1211776001841	active site
1211776001842	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1211776001843	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1211776001845	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1211776001846	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
1211776001847	active site
1211776001848	intersubunit interface [polypeptide binding]; other site
1211776001849	zinc binding site [ion binding]; other site
1211776001850	Na+ binding site [ion binding]; other site
1211776001851	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1211776001852	Protein of unknown function (DUF2570); Region: DUF2570; pfam10828
1211776001854	hypothetical protein; Validated; Region: PRK09039
1211776001855	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1211776001856	ligand binding site [chemical binding]; other site
1211776001858	1-aminocyclopropane-1-carboxylate deaminase [Amino acid transport and metabolism]; Region: Acd; COG2515
1211776001859	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cl00342
1211776001860	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1211776001861	catalytic residue [active]
1211776001862	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1211776001863	Na2 binding site [ion binding]; other site
1211776001864	putative substrate binding site 1 [chemical binding]; other site
1211776001865	Na binding site 1 [ion binding]; other site
1211776001866	putative substrate binding site 2 [chemical binding]; other site
1211776001868	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2258
1211776001869	MOSC domain; Region: MOSC; pfam03473
1211776001870	Thiol:disulfide interchange protein [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4232
1211776001871	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
1211776001872	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
1211776001873	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
1211776001874	DsbD alpha interface [polypeptide binding]; other site
1211776001875	catalytic residues [active]
1211776001877	polyphosphate kinase 2, PA0141 family; Region: PPK2_P_aer; TIGR03707
1211776001878	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1211776001879	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1211776001880	metal binding site [ion binding]; metal-binding site
1211776001881	dimer interface [polypeptide binding]; other site
1211776001882	macrolide transporter subunit MacA; Provisional; Region: PRK11578
1211776001883	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1211776001884	HlyD family secretion protein; Region: HlyD_3; pfam13437
1211776001886	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1211776001887	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
1211776001888	Walker A/P-loop; other site
1211776001889	ATP binding site [chemical binding]; other site
1211776001890	Q-loop/lid; other site
1211776001891	ABC transporter signature motif; other site
1211776001892	Walker B; other site
1211776001893	D-loop; other site
1211776001894	H-loop/switch region; other site
1211776001895	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1211776001896	FtsX-like permease family; Region: FtsX; pfam02687
1211776001898	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1211776001899	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1211776001900	SGNH_peri1; putative periplasmic member of the SGNH-family of hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known...; Region: SGNH_hydrolase_peri1; cd01825
1211776001901	active site
1211776001902	oxyanion hole [active]
1211776001903	catalytic triad [active]
1211776001904	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2845
1211776001905	active site
1211776001906	catalytic triad [active]
1211776001907	oxyanion hole [active]
1211776001909	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1211776001911	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1211776001912	Ferritin-like domain; Region: Ferritin; pfam00210
1211776001913	ferroxidase diiron center [ion binding]; other site
1211776001914	ABC-type phosphate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PstS; COG0226
1211776001915	phosphate ABC transporter, permease protein PstC; Region: phosphate_pstC; TIGR02138
1211776001916	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776001917	dimer interface [polypeptide binding]; other site
1211776001918	conserved gate region; other site
1211776001919	putative PBP binding loops; other site
1211776001920	ABC-ATPase subunit interface; other site
1211776001922	Domain of unknown function (DUF3333); Region: DUF3333; pfam11812
1211776001923	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1211776001924	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776001925	dimer interface [polypeptide binding]; other site
1211776001926	conserved gate region; other site
1211776001927	putative PBP binding loops; other site
1211776001928	ABC-ATPase subunit interface; other site
1211776001930	phosphate ABC transporter ATP-binding protein; Provisional; Region: PRK14269
1211776001931	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1211776001932	Walker A/P-loop; other site
1211776001933	ATP binding site [chemical binding]; other site
1211776001934	Q-loop/lid; other site
1211776001935	ABC transporter signature motif; other site
1211776001936	Walker B; other site
1211776001937	D-loop; other site
1211776001938	H-loop/switch region; other site
1211776001939	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776001940	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776001941	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1211776001942	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1211776001944	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
1211776001945	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypF; COG0068
1211776001946	Acylphosphatase; Region: Acylphosphatase; pfam00708
1211776001947	HypF finger; Region: zf-HYPF; pfam07503
1211776001948	HypF finger; Region: zf-HYPF; pfam07503
1211776001949	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
1211776001950	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1211776001951	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypC; COG0298
1211776001952	hydrogenase isoenzymes formation protein HypD; Provisional; Region: PRK15062
1211776001953	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
1211776001954	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
1211776001955	dimerization interface [polypeptide binding]; other site
1211776001956	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
1211776001957	ATP binding site [chemical binding]; other site
1211776001958	Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) [General function prediction only]; Region: HybF; COG0375
1211776001959	Hydrogenase expression/synthesis hypA family; Region: HypA; pfam01155
1211776001960	Autotransporter beta-domain; Region: Autotransporter; smart00869
1211776001961	DNA polymerase III subunit delta; Validated; Region: PRK08487
1211776001962	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1211776001963	Exoribonuclease R [Transcription]; Region: VacB; COG0557
1211776001964	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1211776001965	RNB domain; Region: RNB; pfam00773
1211776001966	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1211776001967	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1211776001968	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1211776001969	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
1211776001970	NodB motif; other site
1211776001971	putative active site [active]
1211776001972	putative catalytic site [active]
1211776001973	Zn binding site [ion binding]; other site
1211776001975	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1211776001976	DNA protecting protein DprA; Region: dprA; TIGR00732
1211776001977	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
1211776001978	NOL1/NOP2/sun family; Region: Nol1_Nop2_Fmu; pfam01189
1211776001979	NOL1/NOP2/sun family putative RNA methylase; Region: nop2p; TIGR00446
1211776001980	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1211776001981	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
1211776001982	dimer interface [polypeptide binding]; other site
1211776001983	substrate binding site [chemical binding]; other site
1211776001984	metal binding sites [ion binding]; metal-binding site
1211776001985	adenylate kinase; Reviewed; Region: adk; PRK00279
1211776001986	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1211776001987	AMP-binding site [chemical binding]; other site
1211776001988	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1211776001989	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1211776001990	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1211776001991	dimer interface [polypeptide binding]; other site
1211776001992	anticodon binding site; other site
1211776001993	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1211776001994	homodimer interface [polypeptide binding]; other site
1211776001995	motif 1; other site
1211776001996	active site
1211776001997	motif 2; other site
1211776001998	GAD domain; Region: GAD; pfam02938
1211776001999	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1211776002000	active site
1211776002001	motif 3; other site
1211776002002	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: pnk; PRK14077
1211776002003	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1211776002004	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1211776002005	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776002006	Walker A/P-loop; other site
1211776002007	ATP binding site [chemical binding]; other site
1211776002008	Q-loop/lid; other site
1211776002009	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1211776002010	ABC transporter signature motif; other site
1211776002011	Walker B; other site
1211776002012	D-loop; other site
1211776002013	H-loop/switch region; other site
1211776002014	Response regulator containing a CheY-like receiver domain and a GGDEF domain [Signal transduction mechanisms]; Region: PleD; COG3706
1211776002015	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776002016	active site
1211776002017	phosphorylation site [posttranslational modification]
1211776002018	intermolecular recognition site; other site
1211776002019	dimerization interface [polypeptide binding]; other site
1211776002020	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776002021	active site
1211776002022	phosphorylation site [posttranslational modification]
1211776002023	intermolecular recognition site; other site
1211776002024	dimerization interface [polypeptide binding]; other site
1211776002025	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1211776002026	metal binding site [ion binding]; metal-binding site
1211776002027	active site
1211776002028	I-site; other site
1211776002029	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1211776002030	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1211776002031	active site
1211776002032	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1211776002033	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1211776002034	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1211776002035	catalytic residue [active]
1211776002036	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1211776002037	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1211776002038	Lipoproteins [Cell envelope biogenesis, outer membrane]; Region: RlpA; COG0797
1211776002039	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
1211776002040	Sporulation related domain; Region: SPOR; pfam05036
1211776002042	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776002043	active site
1211776002044	motif I; other site
1211776002045	motif II; other site
1211776002047	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
1211776002048	OstA-like protein; Region: OstA; pfam03968
1211776002049	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1211776002050	G1 box; other site
1211776002051	GTP/Mg2+ binding site [chemical binding]; other site
1211776002052	Switch I region; other site
1211776002053	G2 box; other site
1211776002054	G3 box; other site
1211776002055	Switch II region; other site
1211776002056	G4 box; other site
1211776002057	G5 box; other site
1211776002059	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1211776002060	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1211776002061	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1211776002063	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1211776002064	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1211776002065	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1211776002066	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1211776002067	active site
1211776002073	GTPase Era; Reviewed; Region: era; PRK00089
1211776002074	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1211776002075	G1 box; other site
1211776002076	GTP/Mg2+ binding site [chemical binding]; other site
1211776002077	Switch I region; other site
1211776002078	G2 box; other site
1211776002079	Switch II region; other site
1211776002080	G3 box; other site
1211776002081	G4 box; other site
1211776002082	G5 box; other site
1211776002083	KH domain; Region: KH_2; pfam07650
1211776002084	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1211776002085	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776002086	Walker A motif; other site
1211776002087	ATP binding site [chemical binding]; other site
1211776002088	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
1211776002089	Walker B motif; other site
1211776002090	arginine finger; other site
1211776002091	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1211776002092	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1211776002093	active site
1211776002094	HslU subunit interaction site [polypeptide binding]; other site
1211776002095	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1211776002096	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1211776002097	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1211776002098	argininosuccinate synthase; Provisional; Region: PRK13820
1211776002099	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1211776002100	ANP binding site [chemical binding]; other site
1211776002101	Substrate Binding Site II [chemical binding]; other site
1211776002102	Substrate Binding Site I [chemical binding]; other site
1211776002103	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) [Translation, ribosomal structure and biogenesis]; Region: COG1188
1211776002104	RNA binding surface [nucleotide binding]; other site
1211776002105	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1211776002106	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
1211776002107	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
1211776002108	Walker A/P-loop; other site
1211776002109	ATP binding site [chemical binding]; other site
1211776002110	Q-loop/lid; other site
1211776002111	ABC transporter signature motif; other site
1211776002112	Walker B; other site
1211776002113	D-loop; other site
1211776002114	H-loop/switch region; other site
1211776002115	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
1211776002116	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
1211776002117	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
1211776002118	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
1211776002119	Anaerobic C4-dicarboxylate transporter [General function prediction only]; Region: DcuB; COG2704
1211776002120	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
1211776002126	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
1211776002127	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1211776002128	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1211776002133	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
1211776002134	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
1211776002135	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1211776002136	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1211776002138	excinuclease ABC subunit B; Provisional; Region: PRK05298
1211776002139	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1211776002140	ATP binding site [chemical binding]; other site
1211776002141	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1211776002142	nucleotide binding region [chemical binding]; other site
1211776002143	ATP-binding site [chemical binding]; other site
1211776002144	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1211776002146	primosome assembly protein PriA; Validated; Region: PRK05580
1211776002147	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1211776002148	ATP binding site [chemical binding]; other site
1211776002149	putative Mg++ binding site [ion binding]; other site
1211776002150	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1211776002151	ATP-binding site [chemical binding]; other site
1211776002152	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
1211776002153	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1211776002154	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1211776002155	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1211776002156	Flagellar basal body L-ring protein [Cell motility and secretion]; Region: FlgH; COG2063
1211776002157	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
1211776002158	BioD-like N-terminal domain of phosphotransacetylase [General function prediction only]; Region: Pta; COG0857
1211776002159	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1211776002160	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1211776002161	propionate/acetate kinase; Provisional; Region: PRK12379
1211776002162	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1211776002163	Type II restriction enzyme, methylase subunits [Defense mechanisms]; Region: COG1002
1211776002164	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1211776002167	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
1211776002168	MraW methylase family; Region: Methyltransf_5; cl17771
1211776002169	SurA N-terminal domain; Region: SurA_N_3; cl07813
1211776002170	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
1211776002171	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1211776002173	cell division protein FtsA; Region: ftsA; TIGR01174
1211776002174	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1211776002175	nucleotide binding site [chemical binding]; other site
1211776002176	SHS2 domain inserted in FTSA; Region: SHS2_FTSA; pfam02491
1211776002177	Cell division protein FtsA; Region: FtsA; pfam14450
1211776002178	cell division protein FtsZ; Validated; Region: PRK09330
1211776002179	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1211776002180	nucleotide binding site [chemical binding]; other site
1211776002181	SulA interaction site; other site
1211776002182	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgG; COG4786
1211776002183	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1211776002184	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
1211776002185	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1211776002186	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1211776002187	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1211776002188	glutamine synthetase, type I; Region: GlnA; TIGR00653
1211776002189	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1211776002190	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1211776002191	Chemotaxis phosphatase, CheZ; Region: CheZ; cl01219
1211776002192	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1211776002193	Peptidase family U32; Region: Peptidase_U32; pfam01136
1211776002194	AIR carboxylase; Region: AIRC; smart01001
1211776002195	Protein of unknown function (DUF3972); Region: DUF3972; pfam13118
1211776002196	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
1211776002197	dimer interface [polypeptide binding]; other site
1211776002198	motif 1; other site
1211776002199	active site
1211776002200	motif 2; other site
1211776002201	motif 3; other site
1211776002202	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1211776002203	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1211776002204	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
1211776002205	Putative zinc ribbon domain; Region: DUF164; pfam02591
1211776002206	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
1211776002207	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
1211776002209	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1211776002210	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1211776002211	active site
1211776002212	signal recognition particle protein; Provisional; Region: PRK10867
1211776002213	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1211776002214	P loop; other site
1211776002215	GTP binding site [chemical binding]; other site
1211776002216	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1211776002217	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1211776002218	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1211776002219	KH domain; Region: KH_4; pfam13083
1211776002220	G-X-X-G motif; other site
1211776002221	RimM protein, required for 16S rRNA processing [Translation, ribosomal structure and biogenesis]; Region: RimM; COG0806
1211776002222	RimM N-terminal domain; Region: RimM; pfam01782
1211776002223	PRC-barrel domain; Region: PRC; pfam05239
1211776002224	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1211776002225	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1211776002226	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
1211776002227	active site
1211776002228	homotetramer interface [polypeptide binding]; other site
1211776002229	Class-II DAHP synthetase family; Region: DAHP_synth_2; pfam01474
1211776002230	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1211776002231	ArsC family; Region: ArsC; pfam03960
1211776002232	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1211776002233	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
1211776002234	active site
1211776002235	PHP Thumb interface [polypeptide binding]; other site
1211776002236	metal binding site [ion binding]; metal-binding site
1211776002237	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1211776002238	generic binding surface I; other site
1211776002239	generic binding surface II; other site
1211776002240	Predicted enzyme with a TIM-barrel fold [General function prediction only]; Region: COG0325
1211776002241	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1211776002242	catalytic residue [active]
1211776002243	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1211776002244	flagellin; Provisional; Region: PRK12804
1211776002246	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1211776002247	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776002248	S-adenosylmethionine binding site [chemical binding]; other site
1211776002249	Peptidase family M48; Region: Peptidase_M48; pfam01435
1211776002251	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1211776002252	MPT binding site; other site
1211776002253	trimer interface [polypeptide binding]; other site
1211776002254	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1211776002255	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1211776002256	oligomer interface [polypeptide binding]; other site
1211776002258	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
1211776002259	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
1211776002260	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4222
1211776002261	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1211776002262	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4132
1211776002264	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1211776002265	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002266	dimer interface [polypeptide binding]; other site
1211776002267	conserved gate region; other site
1211776002268	putative PBP binding loops; other site
1211776002269	ABC-ATPase subunit interface; other site
1211776002271	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1211776002272	ATP-binding cassette domain of the carbohydrate and solute transporters-like; Region: ABC_Carb_Solutes_like; cd03259
1211776002273	Walker A/P-loop; other site
1211776002274	ATP binding site [chemical binding]; other site
1211776002275	Q-loop/lid; other site
1211776002276	ABC transporter signature motif; other site
1211776002277	Walker B; other site
1211776002278	D-loop; other site
1211776002279	H-loop/switch region; other site
1211776002280	TOBE domain; Region: TOBE_2; pfam08402
1211776002281	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1211776002282	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1211776002283	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1211776002284	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1211776002285	substrate binding pocket [chemical binding]; other site
1211776002286	membrane-bound complex binding site; other site
1211776002287	hinge residues; other site
1211776002289	Large exoproteins involved in heme utilization or adhesion [Intracellular trafficking and secretion]; Region: FhaB; COG3210
1211776002290	haemagglutination activity domain; Region: Haemagg_act; smart00912
1211776002294	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1211776002295	TonB family C-terminal domain; Region: tonB_Cterm; TIGR01352
1211776002297	Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism]; Region: FepA; COG4771
1211776002298	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1211776002299	N-terminal plug; other site
1211776002300	ligand-binding site [chemical binding]; other site
1211776002301	heat-inducible transcription repressor; Provisional; Region: PRK03911
1211776002302	Molecular chaperone GrpE (heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: GrpE; COG0576
1211776002303	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1211776002304	dimer interface [polypeptide binding]; other site
1211776002305	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1211776002306	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1211776002307	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1211776002308	nucleotide binding site [chemical binding]; other site
1211776002309	NEF interaction site [polypeptide binding]; other site
1211776002310	SBD interface [polypeptide binding]; other site
1211776002311	Predicted Zn-dependent hydrolases of the beta-lactamase fold [General function prediction only]; Region: COG2220
1211776002312	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
1211776002313	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1211776002314	aspartate aminotransferase; Provisional; Region: PRK05764
1211776002315	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1211776002316	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002317	homodimer interface [polypeptide binding]; other site
1211776002318	catalytic residue [active]
1211776002319	serine O-acetyltransferase; Region: cysE; TIGR01172
1211776002320	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1211776002321	trimer interface [polypeptide binding]; other site
1211776002322	active site
1211776002323	substrate binding site [chemical binding]; other site
1211776002324	CoA binding site [chemical binding]; other site
1211776002325	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
1211776002326	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
1211776002327	dimer interface [polypeptide binding]; other site
1211776002328	active site
1211776002329	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1211776002330	catalytic residues [active]
1211776002331	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1211776002332	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1211776002333	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1211776002334	dimer interface [polypeptide binding]; other site
1211776002335	motif 1; other site
1211776002336	active site
1211776002337	motif 2; other site
1211776002338	motif 3; other site
1211776002339	HGTP anticodon binding domain, as found at the C-terminus of histidyl, glycyl, threonyl and prolyl tRNA synthetases, which are classified as a group of class II aminoacyl-tRNA synthetases (aaRS). In aaRSs, the anticodon binding domain is responsible for...; Region: HGTP_anticodon; cl00266
1211776002340	anticodon binding site; other site
1211776002341	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1211776002342	thymidylate kinase; Validated; Region: tmk; PRK00698
1211776002343	TMP-binding site; other site
1211776002344	ATP-binding site [chemical binding]; other site
1211776002345	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1211776002346	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1211776002347	active site
1211776002348	(T/H)XGH motif; other site
1211776002349	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
1211776002350	Flavoprotein; Region: Flavoprotein; pfam02441
1211776002351	flagellar basal body P-ring biosynthesis protein FlgA; Reviewed; Region: flgA; PRK08515
1211776002352	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
1211776002353	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1211776002354	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1211776002356	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1211776002357	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1211776002358	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1211776002359	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1211776002360	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002361	ABC-ATPase subunit interface; other site
1211776002363	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1211776002364	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1211776002365	Walker A/P-loop; other site
1211776002366	ATP binding site [chemical binding]; other site
1211776002367	Q-loop/lid; other site
1211776002368	ABC transporter signature motif; other site
1211776002369	Walker B; other site
1211776002370	D-loop; other site
1211776002371	H-loop/switch region; other site
1211776002372	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
1211776002373	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1211776002374	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1211776002375	active site
1211776002376	HIGH motif; other site
1211776002377	nucleotide binding site [chemical binding]; other site
1211776002378	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1211776002379	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1211776002380	active site
1211776002381	KMSKS motif; other site
1211776002382	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1211776002383	tRNA binding surface [nucleotide binding]; other site
1211776002384	anticodon binding site; other site
1211776002385	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1211776002387	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
1211776002389	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1211776002390	Part of AAA domain; Region: AAA_19; pfam13245
1211776002391	Family description; Region: UvrD_C_2; pfam13538
1211776002392	Accessory colonization factor AcfC, contains ABC-type periplasmic domain [General function prediction only]; Region: AcfC; COG4588
1211776002393	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1211776002394	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
1211776002395	dimer interface [polypeptide binding]; other site
1211776002396	catalytic triad [active]
1211776002397	peroxidatic and resolving cysteines [active]
1211776002398	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
1211776002399	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
1211776002400	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1211776002401	molybdopterin cofactor binding site; other site
1211776002402	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1211776002403	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
1211776002404	molybdopterin cofactor binding site; other site
1211776002405	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1211776002406	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1211776002408	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
1211776002409	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1211776002410	4Fe-4S binding domain; Region: Fer4; cl02805
1211776002412	Nitrate reductase cytochrome c-type subunit [Energy production and conversion]; Region: NapB; COG3043
1211776002414	FOG: WD40 repeat [General function prediction only]; Region: COG2319
1211776002415	WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from...; Region: WD40; cl02567
1211776002416	Uncharacterized protein involved in formation of periplasmic nitrate reductase [Inorganic ion transport and metabolism]; Region: NapD; COG3062
1211776002418	delta endotoxin, N-terminal domain; Region: Endotoxin_N; pfam03945
1211776002419	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1211776002420	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1211776002421	active site
1211776002422	NTP binding site [chemical binding]; other site
1211776002423	metal binding triad [ion binding]; metal-binding site
1211776002424	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1211776002425	Formyltetrahydrofolate hydrolase [Nucleotide transport and metabolism]; Region: PurU; COG0788
1211776002426	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
1211776002427	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
1211776002428	putative active site [active]
1211776002429	putative substrate binding site [chemical binding]; other site
1211776002430	putative cosubstrate binding site; other site
1211776002431	catalytic site [active]
1211776002432	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1211776002433	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1211776002434	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1211776002435	catalytic residue [active]
1211776002436	Archaea bacterial proteins of unknown function; Region: DUF234; pfam03008
1211776002437	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776002438	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1211776002439	dimer interface [polypeptide binding]; other site
1211776002440	phosphorylation site [posttranslational modification]
1211776002441	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776002442	ATP binding site [chemical binding]; other site
1211776002443	Mg2+ binding site [ion binding]; other site
1211776002444	G-X-G motif; other site
1211776002445	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1211776002446	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1211776002448	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1211776002449	Antitoxin Phd_YefM, type II toxin-antitoxin system; Region: PhdYeFM_antitox; pfam02604
1211776002450	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1211776002451	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1211776002452	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1211776002453	Holliday junction DNA helicase RuvA; Provisional; Region: ruvA; PRK14601
1211776002454	RuvA N terminal domain; Region: RuvA_N; pfam01330
1211776002455	Ribosomal protein S13/S18; Region: Ribosomal_S13; cl00331
1211776002456	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1211776002458	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1211776002459	integral membrane protein MviN; Region: mviN; TIGR01695
1211776002460	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
1211776002462	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1211776002463	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1211776002464	active site
1211776002465	HIGH motif; other site
1211776002466	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1211776002467	KMSKS motif; other site
1211776002468	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1211776002469	tRNA binding surface [nucleotide binding]; other site
1211776002470	anticodon binding site; other site
1211776002471	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1211776002472	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1211776002473	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776002474	Walker A/P-loop; other site
1211776002475	ATP binding site [chemical binding]; other site
1211776002476	Q-loop/lid; other site
1211776002477	ABC transporter signature motif; other site
1211776002478	Walker B; other site
1211776002479	D-loop; other site
1211776002480	H-loop/switch region; other site
1211776002482	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
1211776002483	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
1211776002484	quinone interaction residues [chemical binding]; other site
1211776002485	active site
1211776002486	catalytic residues [active]
1211776002487	FMN binding site [chemical binding]; other site
1211776002488	substrate binding site [chemical binding]; other site
1211776002489	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1211776002490	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1211776002491	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1211776002492	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1211776002493	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1211776002494	dimer interface [polypeptide binding]; other site
1211776002495	active site
1211776002496	catalytic residue [active]
1211776002497	7-alpha-hydroxysteroid dehydrogenase; Provisional; Region: PRK08416
1211776002498	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1211776002499	NAD(P) binding site [chemical binding]; other site
1211776002500	active site
1211776002502	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1211776002503	NAD synthetase; Provisional; Region: PRK13980
1211776002504	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1211776002505	homodimer interface [polypeptide binding]; other site
1211776002506	NAD binding pocket [chemical binding]; other site
1211776002507	ATP binding pocket [chemical binding]; other site
1211776002508	Mg binding site [ion binding]; other site
1211776002509	active-site loop [active]
1211776002510	Tetraacyldisaccharide-1-P 4'-kinase [Cell envelope biogenesis, outer membrane]; Region: LpxK; COG1663
1211776002511	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
1211776002513	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1211776002514	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1211776002515	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002516	catalytic residue [active]
1211776002517	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1211776002518	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
1211776002519	Ligand binding site; other site
1211776002520	oligomer interface; other site
1211776002521	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1211776002522	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1211776002523	substrate binding pocket [chemical binding]; other site
1211776002524	membrane-bound complex binding site; other site
1211776002525	hinge residues; other site
1211776002528	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1211776002530	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14359
1211776002531	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1211776002532	Substrate binding site; other site
1211776002533	Mg++ binding site; other site
1211776002534	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1211776002535	active site
1211776002536	substrate binding site [chemical binding]; other site
1211776002537	CoA binding site [chemical binding]; other site
1211776002538	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1211776002539	Flavoprotein; Region: Flavoprotein; pfam02441
1211776002540	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1211776002542	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1211776002543	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1211776002544	catalytic residue [active]
1211776002545	putative FPP diphosphate  binding site; other site
1211776002546	putative FPP binding hydrophobic cleft; other site
1211776002547	dimer interface [polypeptide binding]; other site
1211776002548	putative IPP diphosphate binding site; other site
1211776002549	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1211776002550	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1211776002552	Predicted permeases [General function prediction only]; Region: COG0795
1211776002553	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
1211776002555	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1211776002556	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1211776002557	dimerization interface 3.5A [polypeptide binding]; other site
1211776002558	active site
1211776002559	threonine dehydratase; Provisional; Region: PRK08526
1211776002560	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1211776002561	tetramer interface [polypeptide binding]; other site
1211776002562	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002563	catalytic residue [active]
1211776002564	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
1211776002565	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
1211776002566	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3399
1211776002568	tRNA (Uracil-5-)-methyltransferase; Region: tRNA_U5-meth_tr; pfam05958
1211776002569	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776002570	S-adenosylmethionine binding site [chemical binding]; other site
1211776002571	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
1211776002573	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1211776002574	Short-chain alcohol dehydrogenase of unknown specificity [General function prediction only]; Region: COG4221
1211776002575	NAD(P) binding site [chemical binding]; other site
1211776002576	active site
1211776002577	FOG: Ankyrin repeat [General function prediction only]; Region: Arp; COG0666
1211776002578	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1211776002579	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1211776002580	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
1211776002581	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
1211776002582	substrate binding site [chemical binding]; other site
1211776002583	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
1211776002584	substrate binding site [chemical binding]; other site
1211776002585	ligand binding site [chemical binding]; other site
1211776002586	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
1211776002587	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1211776002588	DNA binding site [nucleotide binding]
1211776002589	active site
1211776002590	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1211776002591	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1211776002592	active site
1211776002593	HIGH motif; other site
1211776002594	KMSKS motif; other site
1211776002595	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1211776002596	tRNA binding surface [nucleotide binding]; other site
1211776002597	anticodon binding site; other site
1211776002598	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1211776002599	putative tRNA-binding site [nucleotide binding]; other site
1211776002600	dimer interface [polypeptide binding]; other site
1211776002601	Fructose-1,6-bisphosphatase [Carbohydrate transport and metabolism]; Region: Fbp; COG0158
1211776002602	active site
1211776002603	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1211776002604	Walker A motif; other site
1211776002605	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1211776002606	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1211776002607	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1211776002608	catalytic residue [active]
1211776002609	YGGT family; Region: YGGT; pfam02325
1211776002611	glutamylglutaminyl-tRNA synthetase; Provisional; Region: PRK12410
1211776002612	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1211776002613	active site
1211776002614	HIGH motif; other site
1211776002615	nucleotide binding site [chemical binding]; other site
1211776002616	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1211776002617	active site
1211776002618	KMSKS motif; other site
1211776002619	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1211776002620	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1211776002621	putative active site [active]
1211776002622	putative metal binding site [ion binding]; other site
1211776002624	phosphatidylserine decarboxylase; Provisional; Region: PRK03934
1211776002625	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1211776002626	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1211776002627	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776002628	putative substrate translocation pore; other site
1211776002629	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1211776002632	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1211776002634	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1211776002635	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1211776002636	inhibitor-cofactor binding pocket; inhibition site
1211776002637	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002638	catalytic residue [active]
1211776002639	ubiquitin-activating enzyme E1; Region: Ube1; TIGR01408
1211776002640	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14166
1211776002641	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1211776002642	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1211776002643	homodimer interface [polypeptide binding]; other site
1211776002644	NADP binding site [chemical binding]; other site
1211776002645	substrate binding site [chemical binding]; other site
1211776002646	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1211776002647	Catalytic site [active]
1211776002648	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1211776002650	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1211776002651	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1211776002652	dimer interface [polypeptide binding]; other site
1211776002653	putative functional site; other site
1211776002654	putative MPT binding site; other site
1211776002655	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1211776002656	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1211776002657	hinge; other site
1211776002658	active site
1211776002659	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1211776002660	EamA-like transporter family; Region: EamA; pfam00892
1211776002662	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1211776002663	Glutamine amidotransferase class-I; Region: GATase; pfam00117
1211776002664	glutamine binding [chemical binding]; other site
1211776002665	catalytic triad [active]
1211776002666	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1211776002667	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1211776002668	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1211776002669	substrate-cofactor binding pocket; other site
1211776002670	homodimer interface [polypeptide binding]; other site
1211776002671	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002672	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cl00224
1211776002673	catalytic residue [active]
1211776002674	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1211776002675	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1211776002676	active site
1211776002677	DNA binding site [nucleotide binding]
1211776002678	Int/Topo IB signature motif; other site
1211776002679	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1211776002680	putative disulfide oxidoreductase; Provisional; Region: PRK04307
1211776002683	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
1211776002684	DSBA-like thioredoxin domain; Region: DSBA; pfam01323
1211776002685	catalytic residues [active]
1211776002686	hinge region; other site
1211776002687	alpha helical domain; other site
1211776002688	Cytochrome c [Energy production and conversion]; Region: COG3258
1211776002689	Cytochrome c [Energy production and conversion]; Region: COG3258
1211776002690	Cytochrome c; Region: Cytochrom_C; pfam00034
1211776002691	DHH family; Region: DHH; pfam01368
1211776002692	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
1211776002693	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1211776002694	FHIPEP family; Region: FHIPEP; pfam00771
1211776002696	Rrf2 family protein; Region: rrf2_super; TIGR00738
1211776002697	Transcriptional regulator; Region: Rrf2; pfam02082
1211776002698	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1211776002699	16S/18S rRNA binding site [nucleotide binding]; other site
1211776002700	S13e-L30e interaction site [polypeptide binding]; other site
1211776002701	25S rRNA binding site [nucleotide binding]; other site
1211776002702	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1211776002703	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1211776002704	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1211776002706	lagellar hook-associated protein FlgL; Provisional; Region: PRK14692
1211776002707	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1211776002708	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1211776002709	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1211776002710	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776002711	Walker A/P-loop; other site
1211776002712	ATP binding site [chemical binding]; other site
1211776002713	Q-loop/lid; other site
1211776002714	ABC transporter signature motif; other site
1211776002715	Walker B; other site
1211776002716	D-loop; other site
1211776002717	H-loop/switch region; other site
1211776002718	ABC transporter; Region: ABC_tran_2; pfam12848
1211776002719	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1211776002720	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776002721	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776002722	ATP binding site [chemical binding]; other site
1211776002723	Mg2+ binding site [ion binding]; other site
1211776002724	G-X-G motif; other site
1211776002726	heavy metal response regulator; Region: cztR_silR_copR; TIGR01387
1211776002727	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776002728	active site
1211776002729	phosphorylation site [posttranslational modification]
1211776002730	intermolecular recognition site; other site
1211776002731	dimerization interface [polypeptide binding]; other site
1211776002732	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1211776002733	DNA binding site [nucleotide binding]
1211776002734	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK13581
1211776002735	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_4; cd12173
1211776002736	ligand binding site [chemical binding]; other site
1211776002737	NAD binding site [chemical binding]; other site
1211776002738	dimerization interface [polypeptide binding]; other site
1211776002739	catalytic site [active]
1211776002740	C-terminal ACT (regulatory) domain of D-3-phosphoglycerate dehydrogenase (3PGDH); Region: ACT_3PGDH-xct; cd04902
1211776002741	putative L-serine binding site [chemical binding]; other site
1211776002743	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
1211776002744	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1211776002745	RNA binding site [nucleotide binding]; other site
1211776002746	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1211776002747	RNA binding site [nucleotide binding]; other site
1211776002748	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1211776002749	RNA binding site [nucleotide binding]; other site
1211776002750	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1211776002751	RNA binding site [nucleotide binding]; other site
1211776002752	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1211776002753	RNA binding site [nucleotide binding]; other site
1211776002754	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1211776002755	RNA binding site [nucleotide binding]; other site
1211776002756	(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); Region: ispH_lytB; TIGR00216
1211776002757	LytB protein; Region: LYTB; pfam02401
1211776002758	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1211776002759	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1211776002760	hinge; other site
1211776002761	active site
1211776002762	phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Region: pheT_bact; TIGR00472
1211776002763	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1211776002764	putative tRNA-binding site [nucleotide binding]; other site
1211776002765	B3/4 domain; Region: B3_4; pfam03483
1211776002766	tRNA synthetase B5 domain; Region: B5; smart00874
1211776002767	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1211776002768	dimer interface [polypeptide binding]; other site
1211776002769	motif 1; other site
1211776002770	motif 3; other site
1211776002771	motif 2; other site
1211776002772	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1211776002773	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1211776002774	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1211776002775	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1211776002776	dimer interface [polypeptide binding]; other site
1211776002777	motif 1; other site
1211776002778	active site
1211776002779	motif 2; other site
1211776002780	motif 3; other site
1211776002781	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1211776002782	nucleotide binding site/active site [active]
1211776002783	HIT family signature motif; other site
1211776002784	catalytic residue [active]
1211776002785	DJ-1 family protein; Region: not_thiJ; TIGR01383
1211776002786	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1211776002787	conserved cys residue [active]
1211776002789	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1211776002790	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002791	dimer interface [polypeptide binding]; other site
1211776002792	conserved gate region; other site
1211776002793	putative PBP binding loops; other site
1211776002794	ABC-ATPase subunit interface; other site
1211776002796	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1211776002797	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1211776002798	Walker A/P-loop; other site
1211776002799	ATP binding site [chemical binding]; other site
1211776002800	Q-loop/lid; other site
1211776002801	ABC transporter signature motif; other site
1211776002802	Walker B; other site
1211776002803	D-loop; other site
1211776002804	H-loop/switch region; other site
1211776002805	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1211776002806	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1211776002808	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1211776002809	alanine racemase; Reviewed; Region: alr; PRK00053
1211776002810	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1211776002811	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1211776002812	catalytic residue [active]
1211776002813	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
1211776002814	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1211776002816	Copper(I)-binding protein [Inorganic ion transport and    metabolism]; Region: COG2847
1211776002818	Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems [General function prediction only]; Region: COG1999
1211776002819	SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c...; Region: SCO; cd02968
1211776002820	Cu(I) binding site [ion binding]; other site
1211776002822	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1211776002823	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1211776002824	dimer interface [polypeptide binding]; other site
1211776002825	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776002826	catalytic residue [active]
1211776002827	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1211776002828	IHF dimer interface [polypeptide binding]; other site
1211776002829	IHF - DNA interface [nucleotide binding]; other site
1211776002830	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
1211776002831	Uncharacterized small protein [Function unknown]; Region: COG2879
1211776002832	carbon starvation protein A; Provisional; Region: PRK15015
1211776002833	Carbon starvation protein CstA; Region: CstA; pfam02554
1211776002834	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
1211776002836	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1211776002837	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1211776002838	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776002839	active site
1211776002840	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002841	dimer interface [polypeptide binding]; other site
1211776002842	conserved gate region; other site
1211776002843	putative PBP binding loops; other site
1211776002844	ABC-ATPase subunit interface; other site
1211776002846	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002847	dimer interface [polypeptide binding]; other site
1211776002848	conserved gate region; other site
1211776002849	putative PBP binding loops; other site
1211776002850	ABC-ATPase subunit interface; other site
1211776002852	bifunctional adhesin/ABC transporter aspartate/glutamate-binding protein; Reviewed; Region: PRK11917
1211776002853	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1211776002854	substrate binding pocket [chemical binding]; other site
1211776002855	membrane-bound complex binding site; other site
1211776002856	hinge residues; other site
1211776002857	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1211776002858	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1211776002859	Walker A/P-loop; other site
1211776002860	ATP binding site [chemical binding]; other site
1211776002861	Q-loop/lid; other site
1211776002862	ABC transporter signature motif; other site
1211776002863	Walker B; other site
1211776002864	D-loop; other site
1211776002865	H-loop/switch region; other site
1211776002866	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1211776002867	Methyltransferase, chemotaxis proteins; Region: MeTrc; smart00138
1211776002868	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776002869	S-adenosylmethionine binding site [chemical binding]; other site
1211776002870	Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain [Cell motility and secretion / Signal transduction mechanisms]; Region: CheB; COG2201
1211776002871	CheB methylesterase; Region: CheB_methylest; pfam01339
1211776002872	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1211776002873	NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; Region: Oxidored_q4; cl00535
1211776002874	Regulator of replication initiation timing [Replication,    recombination, and repair]; Region: COG4467; cl01853
1211776002876	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776002877	active site
1211776002878	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1211776002879	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1211776002881	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1211776002882	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1211776002883	interface (dimer of trimers) [polypeptide binding]; other site
1211776002884	Substrate-binding/catalytic site; other site
1211776002885	Zn-binding sites [ion binding]; other site
1211776002886	GTP-binding protein YchF; Reviewed; Region: PRK09601
1211776002887	YchF GTPase; Region: YchF; cd01900
1211776002888	G1 box; other site
1211776002889	GTP/Mg2+ binding site [chemical binding]; other site
1211776002890	Switch I region; other site
1211776002891	G2 box; other site
1211776002892	Switch II region; other site
1211776002893	G3 box; other site
1211776002894	G4 box; other site
1211776002895	G5 box; other site
1211776002896	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1211776002897	argininosuccinate lyase; Provisional; Region: PRK00855
1211776002898	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1211776002899	active sites [active]
1211776002900	tetramer interface [polypeptide binding]; other site
1211776002901	Phosphoenolpyruvate carboxykinase; Region: PEPCK_ATP; pfam01293
1211776002902	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
1211776002903	active site
1211776002904	substrate-binding site [chemical binding]; other site
1211776002905	metal-binding site [ion binding]
1211776002906	ATP binding site [chemical binding]; other site
1211776002907	Pyruvate/oxaloacetate carboxyltransferase [Energy production and conversion]; Region: COG5016
1211776002908	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1211776002909	active site
1211776002910	catalytic residues [active]
1211776002911	metal binding site [ion binding]; metal-binding site
1211776002912	homodimer binding site [polypeptide binding]; other site
1211776002913	Biotin carboxyl carrier protein [Lipid metabolism]; Region: AccB; COG0511
1211776002914	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1211776002915	carboxyltransferase (CT) interaction site; other site
1211776002916	biotinylation site [posttranslational modification]; other site
1211776002917	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1211776002918	putative substrate binding site 2 [chemical binding]; other site
1211776002919	putative substrate binding site 1 [chemical binding]; other site
1211776002920	Na binding site 1 [ion binding]; other site
1211776002921	Na2 binding site [ion binding]; other site
1211776002923	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
1211776002924	Na2 binding site [ion binding]; other site
1211776002925	putative substrate binding site 1 [chemical binding]; other site
1211776002926	Na binding site 1 [ion binding]; other site
1211776002927	putative substrate binding site 2 [chemical binding]; other site
1211776002929	F0F1 ATP synthase subunit C; Validated; Region: PRK08482
1211776002931	Predicted permeases [General function prediction only]; Region: COG0679
1211776002933	2-acyl-glycerophospho-ethanolamine acyltransferase; Validated; Region: PRK08633
1211776002934	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776002935	putative substrate translocation pore; other site
1211776002936	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1211776002937	putative acyl-acceptor binding pocket; other site
1211776002938	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
1211776002939	acyl-activating enzyme (AAE) consensus motif; other site
1211776002940	AMP binding site [chemical binding]; other site
1211776002941	active site
1211776002942	CoA binding site [chemical binding]; other site
1211776002944	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1211776002945	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776002946	dimer interface [polypeptide binding]; other site
1211776002947	conserved gate region; other site
1211776002948	putative PBP binding loops; other site
1211776002949	ABC-ATPase subunit interface; other site
1211776002951	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1211776002952	FtsX-like permease family; Region: FtsX; pfam02687
1211776002954	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1211776002955	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1211776002956	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1211776002957	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1211776002958	nucleotide binding region [chemical binding]; other site
1211776002959	ATP-binding site [chemical binding]; other site
1211776002960	SEC-C motif; Region: SEC-C; pfam02810
1211776002961	lipoprotein chaperone; Reviewed; Region: lolA; PRK00031
1211776002962	Outer membrane lipoprotein carrier protein LolA; Region: LolA; pfam03548
1211776002963	PIF1-like helicase; Region: PIF1; pfam05970
1211776002964	Helicase; Region: Herpes_Helicase; pfam02689
1211776002966	NLPC_P60 stabilising domain, N term; Region: N_NLPC_P60; pfam12912
1211776002967	SH3 domain of the SH3b1 type; Region: SH3_6; pfam12913
1211776002968	SH3 domain of SH3b2 type; Region: SH3_7; pfam12914
1211776002969	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1211776002970	NlpC/P60 family; Region: NLPC_P60; cl17555
1211776002971	N-carbamoylputrescine amidohydrolase (CPA) (class 11 nitrilases); Region: CPA; cd07573
1211776002972	N-carbamoylputrescine amidase; Region: agmatine_aguB; TIGR03381
1211776002973	putative active site; other site
1211776002974	catalytic triad [active]
1211776002975	putative dimer interface [polypeptide binding]; other site
1211776002976	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1211776002977	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1211776002979	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957
1211776002980	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1211776002981	Heat shock protein [Posttranslational modification, protein turnover, chaperones]; Region: HslJ; COG3187
1211776002982	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776002983	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776002984	dimer interface [polypeptide binding]; other site
1211776002985	putative CheW interface [polypeptide binding]; other site
1211776002986	Protein of unknown function (DUF3365); Region: DUF3365; pfam11845
1211776002988	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1211776002989	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1211776002990	purine monophosphate binding site [chemical binding]; other site
1211776002991	dimer interface [polypeptide binding]; other site
1211776002992	putative catalytic residues [active]
1211776002993	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1211776002994	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1211776002995	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
1211776002996	DnaJ-domain-containing proteins 1 [Posttranslational modification, protein turnover, chaperones]; Region: DjlA; COG1076
1211776002997	putative metal binding site [ion binding]; other site
1211776002998	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1211776002999	HSP70 interaction site [polypeptide binding]; other site
1211776003000	phosphoribosylformylglycinamidine synthase II; Provisional; Region: PRK01213
1211776003001	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
1211776003002	dimerization interface [polypeptide binding]; other site
1211776003003	ATP binding site [chemical binding]; other site
1211776003004	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
1211776003005	dimerization interface [polypeptide binding]; other site
1211776003006	ATP binding site [chemical binding]; other site
1211776003007	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
1211776003008	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1211776003009	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1211776003010	G1 box; other site
1211776003011	GTP/Mg2+ binding site [chemical binding]; other site
1211776003012	Switch I region; other site
1211776003013	G2 box; other site
1211776003014	Switch II region; other site
1211776003015	G3 box; other site
1211776003016	G4 box; other site
1211776003017	G5 box; other site
1211776003018	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1211776003019	membrane protein insertase; Provisional; Region: PRK01318
1211776003020	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1211776003022	Uncharacterized conserved protein [Function unknown]; Region: COG0759
1211776003023	RNase P protein component [Translation, ribosomal structure and biogenesis]; Region: RnpA; COG0594
1211776003024	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
1211776003025	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776003026	Coenzyme A binding pocket [chemical binding]; other site
1211776003027	Uracil-DNA glycosylase [DNA replication, recombination, and repair]; Region: COG1573
1211776003028	ligand binding site [chemical binding]; other site
1211776003029	active site
1211776003030	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1211776003031	active site
1211776003033	Hemolysin activation/secretion protein [Intracellular trafficking and secretion]; Region: FhaC; COG2831
1211776003034	POTRA domain, ShlB-type; Region: POTRA_2; pfam08479
1211776003035	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1211776003036	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776003037	S-adenosylmethionine binding site [chemical binding]; other site
1211776003038	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1211776003039	active site 1 [active]
1211776003040	active site 2 [active]
1211776003041	Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair]; Region: COG1525
1211776003042	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cd00175
1211776003043	Catalytic site; other site
1211776003045	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1211776003046	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1211776003047	metal binding site [ion binding]; metal-binding site
1211776003048	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776003049	metabolite-proton symporter; Region: 2A0106; TIGR00883
1211776003050	putative substrate translocation pore; other site
1211776003052	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1211776003053	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1211776003054	substrate binding pocket [chemical binding]; other site
1211776003055	membrane-bound complex binding site; other site
1211776003056	hinge residues; other site
1211776003057	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3022
1211776003058	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1211776003059	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_like1; cd05666
1211776003060	metal binding site [ion binding]; metal-binding site
1211776003061	putative dimer interface [polypeptide binding]; other site
1211776003063	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776003064	putative substrate translocation pore; other site
1211776003068	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1211776003069	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1211776003070	Cysteine-rich domain; Region: CCG; pfam02754
1211776003071	Cysteine-rich domain; Region: CCG; pfam02754
1211776003072	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
1211776003073	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776003074	FeS/SAM binding site; other site
1211776003075	HemN C-terminal domain; Region: HemN_C; pfam06969
1211776003076	Protein of unknown function (DUF2603); Region: DUF2603; pfam10788
1211776003077	ornithine carbamoyltransferase; Provisional; Region: PRK00779
1211776003078	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1211776003079	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1211776003080	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1211776003081	dimer interface [polypeptide binding]; other site
1211776003082	active site
1211776003083	Schiff base residues; other site
1211776003084	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1211776003085	dimerization interface [polypeptide binding]; other site
1211776003086	active site
1211776003087	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1211776003088	16S rRNA (guanine(527)-N(7))-methyltransferase GidB; Region: gidB; TIGR00138
1211776003089	Conserved hypothetical protein 698; Region: Cons_hypoth698; pfam03601
1211776003091	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1211776003092	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1211776003093	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
1211776003094	dimerization interface [polypeptide binding]; other site
1211776003095	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
1211776003096	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1211776003097	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1211776003098	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1211776003099	DNA binding residues [nucleotide binding]
1211776003100	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1211776003101	catalytic core [active]
1211776003102	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
1211776003104	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
1211776003105	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003106	Walker A motif; other site
1211776003107	ATP binding site [chemical binding]; other site
1211776003108	Walker B motif; other site
1211776003109	arginine finger; other site
1211776003111	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1211776003112	MiaB-like tRNA modifying enzyme; Region: MiaB-like-C; TIGR01579
1211776003113	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1211776003114	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1211776003116	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1211776003117	active site
1211776003118	dimer interface [polypeptide binding]; other site
1211776003119	metal binding site [ion binding]; metal-binding site
1211776003120	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3400
1211776003121	TrkA-C domain; Region: TrkA_C; pfam02080
1211776003122	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1211776003123	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1211776003124	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1211776003125	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
1211776003128	ResB protein required for cytochrome c biosynthesis [Posttranslational modification, protein turnover, chaperones]; Region: ResB; cl09125
1211776003129	cytochrome c-type biogenesis protein CcsB; Region: cytochr_II_ccsB; TIGR03144
1211776003131	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1211776003132	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1211776003133	Walker A/P-loop; other site
1211776003134	ATP binding site [chemical binding]; other site
1211776003135	Q-loop/lid; other site
1211776003136	ABC transporter signature motif; other site
1211776003137	Walker B; other site
1211776003138	D-loop; other site
1211776003139	H-loop/switch region; other site
1211776003140	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1211776003141	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1211776003142	Walker A/P-loop; other site
1211776003143	ATP binding site [chemical binding]; other site
1211776003144	Q-loop/lid; other site
1211776003145	ABC transporter signature motif; other site
1211776003146	Walker B; other site
1211776003147	D-loop; other site
1211776003148	H-loop/switch region; other site
1211776003149	ABC-type branched-chain amino acid transport system, permease component [Amino acid transport and metabolism]; Region: LivM; COG4177
1211776003150	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1211776003151	TM-ABC transporter signature motif; other site
1211776003153	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1211776003154	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1211776003155	TM-ABC transporter signature motif; other site
1211776003157	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1211776003158	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1211776003159	putative ligand binding site [chemical binding]; other site
1211776003160	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1211776003161	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1211776003162	putative ligand binding site [chemical binding]; other site
1211776003163	Cytochrome c, mono- and diheme variants [Energy production and conversion]; Region: CccA; COG2010
1211776003164	Cytochrome c; Region: Cytochrom_C; cl11414
1211776003166	Campylobacter major outer membrane protein; Region: Campylo_MOMP; pfam05538
1211776003167	Predicted membrane protein [Function unknown]; Region: COG2862
1211776003169	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1211776003170	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1211776003171	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
1211776003172	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776003173	active site
1211776003174	phosphorylation site [posttranslational modification]
1211776003175	intermolecular recognition site; other site
1211776003176	dimerization interface [polypeptide binding]; other site
1211776003177	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003178	Walker A motif; other site
1211776003179	ATP binding site [chemical binding]; other site
1211776003180	Walker B motif; other site
1211776003181	arginine finger; other site
1211776003182	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3018
1211776003183	DNA gyrase subunit A; Validated; Region: PRK05560
1211776003184	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1211776003185	CAP-like domain; other site
1211776003186	active site
1211776003187	primary dimer interface [polypeptide binding]; other site
1211776003188	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1211776003189	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1211776003190	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1211776003191	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1211776003192	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1211776003193	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1211776003194	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776003195	active site
1211776003196	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
1211776003197	GTP-binding protein LepA; Provisional; Region: PRK05433
1211776003198	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1211776003199	G1 box; other site
1211776003200	putative GEF interaction site [polypeptide binding]; other site
1211776003201	GTP/Mg2+ binding site [chemical binding]; other site
1211776003202	Switch I region; other site
1211776003203	G2 box; other site
1211776003204	G3 box; other site
1211776003205	Switch II region; other site
1211776003206	G4 box; other site
1211776003207	G5 box; other site
1211776003208	Translation_Factor_II_like: Elongation factor Tu (EF-Tu) domain II-like proteins. Elongation factor Tu consists of three structural domains, this family represents the second domain. Domain II adopts a beta barrel structure and is involved in binding to...; Region: Translation_Factor_II_like; cl02787
1211776003209	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1211776003210	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1211776003211	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1211776003212	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1211776003213	HlyD family secretion protein; Region: HlyD_3; pfam13437
1211776003214	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1211776003216	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1211776003217	HSP70 interaction site [polypeptide binding]; other site
1211776003218	Putative arginyl-tRNA:protein arginylyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: COG2935
1211776003219	Arginine-tRNA-protein transferase, N terminus; Region: ATE_N; pfam04376
1211776003220	Arginine-tRNA-protein transferase, C terminus; Region: ATE_C; pfam04377
1211776003221	acetyl-CoA carboxylase subunit A; Validated; Region: PRK08463
1211776003222	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1211776003223	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1211776003224	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; pfam02785
1211776003225	cell division protein FtsW; Region: ftsW; TIGR02614
1211776003227	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
1211776003228	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1211776003229	active site
1211776003230	homodimer interface [polypeptide binding]; other site
1211776003231	Cyanate permease [Inorganic ion transport and metabolism]; Region: CynX; COG2807
1211776003233	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1211776003234	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1211776003235	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1211776003236	thiamine phosphate binding site [chemical binding]; other site
1211776003237	active site
1211776003238	pyrophosphate binding site [ion binding]; other site
1211776003239	thiazole biosynthesis protein ThiH; Region: thiH; TIGR02351
1211776003240	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776003241	FeS/SAM binding site; other site
1211776003242	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1211776003243	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1211776003244	ThiS interaction site; other site
1211776003245	putative active site [active]
1211776003246	tetramer interface [polypeptide binding]; other site
1211776003247	ThiS-like ubiquitin; Region: ThiS-like; pfam14453
1211776003248	thiamine biosynthesis protein ThiF, family 2; Region: thiF_fam2; TIGR02354
1211776003249	E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate, on...; Region: E1_ThiF_like; cd01487
1211776003250	putative ATP binding site [chemical binding]; other site
1211776003251	putative substrate interface [chemical binding]; other site
1211776003252	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1211776003253	thiS-thiF/thiG interaction site; other site
1211776003254	succinyl-diaminopimelate desuccinylase, proteobacterial clade; Region: dapE_proteo; TIGR01246
1211776003255	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
1211776003256	metal binding site [ion binding]; metal-binding site
1211776003257	dimer interface [polypeptide binding]; other site
1211776003258	LysE type translocator; Region: LysE; pfam01810
1211776003260	NAD-dependent protein deacetylases, SIR2 family [Transcription]; Region: SIR2; COG0846
1211776003261	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
1211776003262	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1211776003263	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1211776003264	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1211776003265	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1211776003266	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1211776003267	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1211776003268	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1211776003269	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1211776003270	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776003271	Walker A/P-loop; other site
1211776003272	ATP binding site [chemical binding]; other site
1211776003273	Q-loop/lid; other site
1211776003274	ABC transporter signature motif; other site
1211776003275	Walker B; other site
1211776003276	D-loop; other site
1211776003277	H-loop/switch region; other site
1211776003278	Smr domain; Region: Smr; pfam01713
1211776003280	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1211776003281	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1211776003282	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1211776003283	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1211776003284	Sulfatase; Region: Sulfatase; cl17466
1211776003286	Predicted amidohydrolase [General function prediction only]; Region: COG0388
1211776003287	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cd07197
1211776003288	active site
1211776003289	catalytic triad [active]
1211776003290	dimer interface [polypeptide binding]; other site
1211776003291	Exonuclease VII small subunit; Region: Exonuc_VII_S; cl00750
1211776003292	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
1211776003293	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1211776003294	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
1211776003295	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1211776003296	active site
1211776003297	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1211776003298	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1211776003300	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
1211776003301	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1211776003302	active site
1211776003303	HIGH motif; other site
1211776003304	nucleotide binding site [chemical binding]; other site
1211776003305	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1211776003306	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1211776003307	active site
1211776003308	KMSKS motif; other site
1211776003309	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
1211776003310	tRNA binding surface [nucleotide binding]; other site
1211776003311	anticodon binding site; other site
1211776003312	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
1211776003313	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776003314	Coenzyme A binding pocket [chemical binding]; other site
1211776003316	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
1211776003317	dimer interface [polypeptide binding]; other site
1211776003318	FMN binding site [chemical binding]; other site
1211776003319	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1211776003321	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1211776003322	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1211776003323	active site
1211776003324	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1211776003325	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1211776003326	putative substrate binding region [chemical binding]; other site
1211776003328	Uncharacterized protein conserved in bacteria [Function unknown]; Region: VirK; COG2990
1211776003329	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1211776003330	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1211776003331	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1211776003332	dimer interface [polypeptide binding]; other site
1211776003333	ssDNA binding site [nucleotide binding]; other site
1211776003334	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1211776003335	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1211776003336	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1211776003337	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003338	Walker A motif; other site
1211776003339	ATP binding site [chemical binding]; other site
1211776003340	Walker B motif; other site
1211776003341	arginine finger; other site
1211776003342	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1211776003343	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
1211776003344	flagellar assembly protein FliW; Provisional; Region: PRK13282
1211776003345	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1211776003346	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl17232
1211776003350	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
1211776003351	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1211776003352	active site
1211776003353	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1211776003354	thiamine phosphate binding site [chemical binding]; other site
1211776003355	active site
1211776003356	pyrophosphate binding site [ion binding]; other site
1211776003357	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1211776003358	substrate binding site [chemical binding]; other site
1211776003359	dimer interface [polypeptide binding]; other site
1211776003360	ATP binding site [chemical binding]; other site
1211776003361	Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair]; Region: COG2231
1211776003362	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1211776003363	minor groove reading motif; other site
1211776003364	helix-hairpin-helix signature motif; other site
1211776003365	active site
1211776003366	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003367	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
1211776003368	Walker A motif; other site
1211776003369	ATP binding site [chemical binding]; other site
1211776003370	Walker B motif; other site
1211776003371	arginine finger; other site
1211776003372	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1211776003373	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1211776003374	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1211776003375	ATP binding site [chemical binding]; other site
1211776003376	putative Mg++ binding site [ion binding]; other site
1211776003377	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1211776003378	nucleotide binding region [chemical binding]; other site
1211776003379	ATP-binding site [chemical binding]; other site
1211776003380	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1211776003381	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
1211776003382	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
1211776003383	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1211776003384	Peptidase family M23; Region: Peptidase_M23; pfam01551
1211776003386	folylpolyglutamate synthase/dihydrofolate synthase; Region: folC; TIGR01499
1211776003387	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1211776003388	Lipopolysaccharide-assembly; Region: LptE; pfam04390
1211776003389	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1211776003390	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1211776003391	HIGH motif; other site
1211776003392	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1211776003393	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1211776003394	active site
1211776003395	KMSKS motif; other site
1211776003396	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1211776003397	tRNA binding surface [nucleotide binding]; other site
1211776003398	anticodon binding site; other site
1211776003399	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1211776003400	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1211776003401	Protein export membrane protein; Region: SecD_SecF; pfam02355
1211776003403	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
1211776003404	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1211776003406	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1211776003408	apolipoprotein N-acyltransferase; Reviewed; Region: PRK12291
1211776003409	Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes; Region: nitrilase; cl11424
1211776003410	active site
1211776003411	catalytic triad [active]
1211776003412	dimer interface [polypeptide binding]; other site
1211776003414	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1211776003415	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1211776003416	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1211776003417	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1211776003418	Na+/serine symporter [Amino acid transport and metabolism]; Region: SstT; COG3633
1211776003419	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1211776003421	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1211776003422	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1211776003423	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1211776003424	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
1211776003425	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_5; cd09610
1211776003426	active site
1211776003427	Zn binding site [ion binding]; other site
1211776003428	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1211776003429	Part of AAA domain; Region: AAA_19; pfam13245
1211776003430	Family description; Region: UvrD_C_2; pfam13538
1211776003431	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK04099
1211776003432	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1211776003433	active site
1211776003434	RNA-binding global regulator CsrA [Signal transduction mechanisms]; Region: CsrA; COG1551
1211776003435	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK04181
1211776003436	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1211776003437	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1211776003438	SmpB-tmRNA interface; other site
1211776003439	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1211776003440	catalytic residues [active]
1211776003441	Uncharacterized conserved protein [Function unknown]; Region: COG2127
1211776003442	ATP-dependent Clp protease ATP-binding subunit clpA; Region: ClpA; TIGR02639
1211776003443	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003444	Walker A motif; other site
1211776003445	ATP binding site [chemical binding]; other site
1211776003446	Walker B motif; other site
1211776003447	arginine finger; other site
1211776003448	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003449	Walker A motif; other site
1211776003450	ATP binding site [chemical binding]; other site
1211776003451	Walker B motif; other site
1211776003452	arginine finger; other site
1211776003453	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1211776003454	Leu/Phe-tRNA-protein transferase [Posttranslational modification, protein turnover, chaperones]; Region: Aat; COG2360
1211776003455	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1211776003456	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1211776003457	putative active site [active]
1211776003458	heme pocket [chemical binding]; other site
1211776003459	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1211776003460	putative active site [active]
1211776003461	heme pocket [chemical binding]; other site
1211776003462	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776003463	dimer interface [polypeptide binding]; other site
1211776003464	putative CheW interface [polypeptide binding]; other site
1211776003465	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
1211776003467	methionine sulfoxide reductase B; Provisional; Region: PRK05508
1211776003468	Conserved domain frequently associated with peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]; Region: COG0229
1211776003469	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1211776003470	dinuclear metal binding motif [ion binding]; other site
1211776003471	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
1211776003472	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1211776003474	Phosphatidylserine decarboxylase [Lipid metabolism]; Region: Psd; COG0688
1211776003476	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1211776003477	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003478	Walker A motif; other site
1211776003479	ATP binding site [chemical binding]; other site
1211776003480	Walker B motif; other site
1211776003481	arginine finger; other site
1211776003482	Peptidase family M41; Region: Peptidase_M41; pfam01434
1211776003484	Ribosomal protein L11 methylase [Translation, ribosomal structure and biogenesis]; Region: PrmA; COG2264
1211776003485	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776003486	S-adenosylmethionine binding site [chemical binding]; other site
1211776003487	chemotaxis regulatory protein CheY; Provisional; Region: PRK10610
1211776003488	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776003489	active site
1211776003490	phosphorylation site [posttranslational modification]
1211776003491	intermolecular recognition site; other site
1211776003492	dimerization interface [polypeptide binding]; other site
1211776003493	Cache domain; Region: Cache_1; pfam02743
1211776003495	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
1211776003496	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1211776003497	NAD(P) binding site [chemical binding]; other site
1211776003498	homodimer interface [polypeptide binding]; other site
1211776003499	substrate binding site [chemical binding]; other site
1211776003500	active site
1211776003502	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
1211776003503	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1211776003504	inhibitor-cofactor binding pocket; inhibition site
1211776003505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776003506	catalytic residue [active]
1211776003508	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1211776003509	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1211776003510	putative trimer interface [polypeptide binding]; other site
1211776003511	putative CoA binding site [chemical binding]; other site
1211776003512	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1211776003514	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1211776003515	This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides; Region: GT1_cap1E_like; cd03808
1211776003516	putative ADP-binding pocket [chemical binding]; other site
1211776003517	Oligosaccharyl transferase STT3 subunit; Region: STT3; pfam02516
1211776003519	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1211776003520	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1211776003521	putative ADP-binding pocket [chemical binding]; other site
1211776003522	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003523	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776003524	active site
1211776003525	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1211776003526	This family is most closely related to the GT1 family of glycosyltransferases. AmSD in Erwinia amylovora has been shown to be involved in the biosynthesis of amylovoran, the acidic exopolysaccharide acting as a virulence factor. This enzyme may be...; Region: GT1_amsD_like; cd03820
1211776003527	putative ADP-binding pocket [chemical binding]; other site
1211776003528	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1211776003529	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1211776003530	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776003531	Walker A/P-loop; other site
1211776003532	ATP binding site [chemical binding]; other site
1211776003533	Q-loop/lid; other site
1211776003534	ABC transporter signature motif; other site
1211776003535	Walker B; other site
1211776003536	D-loop; other site
1211776003537	H-loop/switch region; other site
1211776003539	UDP-glucose-4-epimerase GalE; Region: galE; TIGR01179
1211776003540	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1211776003541	NAD binding site [chemical binding]; other site
1211776003542	homodimer interface [polypeptide binding]; other site
1211776003543	active site
1211776003544	substrate binding site [chemical binding]; other site
1211776003545	Uncharacterized bacterial subgroup of the DEDDy 3'-5' exonuclease domain of family-B DNA polymerases; Region: DNA_polB_like1_exo; cd05782
1211776003546	active site
1211776003547	catalytic site [active]
1211776003548	substrate binding site [chemical binding]; other site
1211776003549	Predicted 3'-5' exonuclease related to the exonuclease domain of PolB; Region: DNA_pol_B_exo2; pfam10108
1211776003550	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1211776003551	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1211776003552	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1211776003553	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1211776003554	putative active site [active]
1211776003555	Bacterial lipid A biosynthesis acyltransferase; Region: Lip_A_acyltrans; pfam03279
1211776003556	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
1211776003557	putative acyl-acceptor binding pocket; other site
1211776003559	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003560	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1211776003561	putative metal binding site; other site
1211776003562	N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase; Region: GT2_Chondriotin_Pol_N; cd06420
1211776003563	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003564	Substrate binding site; other site
1211776003565	metal-binding site
1211776003566	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776003567	active site
1211776003568	Capsular polysaccharide synthesis protein; Region: Caps_synth; pfam05704
1211776003569	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003570	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776003571	active site
1211776003572	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003573	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776003574	active site
1211776003575	Alpha-2,3-sialyltransferase (CST-I); Region: CST-I; pfam06002
1211776003576	Sialic acid synthase [Cell envelope biogenesis, outer membrane]; Region: SpsE; COG2089
1211776003577	NeuB family; Region: NeuB; pfam03102
1211776003578	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1211776003579	NeuB binding interface [polypeptide binding]; other site
1211776003580	putative substrate binding site [chemical binding]; other site
1211776003581	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1211776003582	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1211776003583	active site
1211776003584	homodimer interface [polypeptide binding]; other site
1211776003585	Beta-1,4-N-acetylgalactosaminyltransferase (CgtA); Region: CgtA; pfam06306
1211776003586	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1211776003587	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
1211776003588	ligand binding site; other site
1211776003589	tetramer interface; other site
1211776003590	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
1211776003591	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776003592	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776003593	active site
1211776003594	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
1211776003595	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
1211776003596	putative active site [active]
1211776003597	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1211776003598	dimer interface [polypeptide binding]; other site
1211776003599	active site
1211776003600	ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaE; COG2870
1211776003601	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
1211776003602	putative ribose interaction site [chemical binding]; other site
1211776003603	putative ADP binding site [chemical binding]; other site
1211776003604	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
1211776003605	active site
1211776003606	nucleotide binding site [chemical binding]; other site
1211776003607	HIGH motif; other site
1211776003608	KMSKS motif; other site
1211776003609	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1211776003610	ADP-L-glycero-D-manno-heptose-6-epimerase; Region: heptose_epim; TIGR02197
1211776003611	NAD(P) binding site [chemical binding]; other site
1211776003612	active site
1211776003613	Histidinol phosphatase and related phosphatases [Amino acid transport and metabolism]; Region: HisB; COG0241
1211776003614	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776003615	active site
1211776003616	motif I; other site
1211776003617	motif II; other site
1211776003618	Cytochrome c553 [Energy production and conversion]; Region: COG2863
1211776003620	Uncharacterized protein, possibly involved in nitrogen fixation [Inorganic ion transport and metabolism]; Region: FixS; COG3197
1211776003622	Putative metal-binding domain of cation transport ATPase; Region: ATPase-cat_bd; pfam12156
1211776003623	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1211776003624	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1211776003625	metal-binding site [ion binding]
1211776003626	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1211776003627	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776003628	motif II; other site
1211776003630	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1211776003631	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
1211776003632	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1211776003633	RNA binding site [nucleotide binding]; other site
1211776003634	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1211776003635	multimer interface [polypeptide binding]; other site
1211776003636	Walker A motif; other site
1211776003637	ATP binding site [chemical binding]; other site
1211776003638	Walker B motif; other site
1211776003639	DNA polymerase III subunits gamma and tau; Validated; Region: PRK08451
1211776003640	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776003641	Walker A motif; other site
1211776003642	ATP binding site [chemical binding]; other site
1211776003643	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1211776003644	Walker B motif; other site
1211776003645	Predicted small integral membrane protein [Function unknown]; Region: COG5472
1211776003647	Predicted small integral membrane protein (DUF2165); Region: DUF2165; cl02290
1211776003649	Predicted small integral membrane protein [Function unknown]; Region: COG5472
1211776003651	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1211776003652	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1211776003653	metal-binding site [ion binding]
1211776003654	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1211776003656	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1211776003658	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3809
1211776003659	Uncharacterized conserved protein [Function unknown]; Region: COG3610
1211776003661	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1211776003662	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1211776003664	Malate/lactate dehydrogenases [Energy production and conversion]; Region: Mdh; COG0039
1211776003665	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
1211776003666	NAD binding site [chemical binding]; other site
1211776003667	dimer interface [polypeptide binding]; other site
1211776003668	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1211776003669	substrate binding site [chemical binding]; other site
1211776003670	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1211776003671	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1211776003673	Protein of unknown function (DUF3373); Region: DUF3373; pfam11853
1211776003674	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1211776003675	active site
1211776003676	hypothetical protein; Provisional; Region: PRK12378
1211776003677	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1211776003679	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
1211776003681	Arginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Region: ArgS; COG0018
1211776003682	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1211776003683	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1211776003684	active site
1211776003685	HIGH motif; other site
1211776003686	KMSK motif region; other site
1211776003687	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1211776003688	tRNA binding surface [nucleotide binding]; other site
1211776003689	anticodon binding site; other site
1211776003690	twin arginine-targeting protein translocase, TatA/E family; Region: tatAE; TIGR01411
1211776003692	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1211776003693	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1211776003694	catalytic site [active]
1211776003695	G-X2-G-X-G-K; other site
1211776003696	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1211776003698	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1211776003699	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1211776003700	Walker A/P-loop; other site
1211776003701	ATP binding site [chemical binding]; other site
1211776003702	Q-loop/lid; other site
1211776003703	ABC transporter signature motif; other site
1211776003704	Walker B; other site
1211776003705	D-loop; other site
1211776003706	H-loop/switch region; other site
1211776003707	elongation factor Ts; Provisional; Region: tsf; PRK09377
1211776003708	UBA/TS-N domain; Region: UBA; pfam00627
1211776003709	Elongation factor TS; Region: EF_TS; pfam00889
1211776003710	Elongation factor TS; Region: EF_TS; pfam00889
1211776003711	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1211776003712	rRNA interaction site [nucleotide binding]; other site
1211776003713	S8 interaction site; other site
1211776003714	putative laminin-1 binding site; other site
1211776003715	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1211776003716	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776003717	S-adenosylmethionine binding site [chemical binding]; other site
1211776003718	Cytochrome c1 [Energy production and conversion]; Region: CYT1; COG2857
1211776003719	Cytochrome c; Region: Cytochrom_C; pfam00034
1211776003721	Cytochrome b subunit of the bc complex [Energy production and conversion]; Region: QcrB; COG1290
1211776003722	Cytochrome b (N-terminus)/b6/petB:  Cytochrome b is a subunit of cytochrome bc1, an 11-subunit mitochondrial respiratory enzyme. Cytochrome b spans the mitochondrial membrane with 8 transmembrane helices (A-H) in eukaryotes. In plants and cyanobacteria; Region: Cytochrome_b_N; cd00284
1211776003723	intrachain domain interface; other site
1211776003724	interchain domain interface [polypeptide binding]; other site
1211776003725	heme bH binding site [chemical binding]; other site
1211776003726	Qi binding site; other site
1211776003727	heme bL binding site [chemical binding]; other site
1211776003728	Qo binding site; other site
1211776003729	interchain domain interface [polypeptide binding]; other site
1211776003730	intrachain domain interface; other site
1211776003731	Qi binding site; other site
1211776003732	Cytochrome b(C-terminal)/b6/petD; Region: Cytochrom_B_C; pfam00032
1211776003733	Qo binding site; other site
1211776003735	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
1211776003736	Iron-sulfur protein (ISP) component of the bc(1) complex family, Rieske domain; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. The bc(1) complex is a multisubunit enzyme found in many different organisms including...; Region: Rieske_cytochrome_bc1; cd03470
1211776003737	[2Fe-2S] cluster binding site [ion binding]; other site
1211776003739	arsenical pump membrane protein; Provisional; Region: PRK15445
1211776003740	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
1211776003741	transmembrane helices; other site
1211776003743	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1211776003744	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1211776003745	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1211776003746	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1211776003747	PAS domain; Region: PAS_9; pfam13426
1211776003748	putative active site [active]
1211776003749	heme pocket [chemical binding]; other site
1211776003750	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776003751	dimer interface [polypeptide binding]; other site
1211776003752	putative CheW interface [polypeptide binding]; other site
1211776003754	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1211776003755	PAS domain; Region: PAS_9; pfam13426
1211776003756	putative active site [active]
1211776003757	heme pocket [chemical binding]; other site
1211776003758	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1211776003759	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1211776003761	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
1211776003762	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1211776003763	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
1211776003765	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1211776003766	dihydroorotase; Provisional; Region: PRK08417
1211776003767	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1211776003768	active site
1211776003769	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1211776003770	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1211776003771	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1211776003772	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1211776003773	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1211776003774	GatB domain; Region: GatB_Yqey; smart00845
1211776003775	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1211776003776	Isopenicillin N synthase and related dioxygenases [General function prediction only]; Region: PcbC; COG3491
1211776003777	non-haem dioxygenase in morphine synthesis N-terminal; Region: DIOX_N; pfam14226
1211776003778	2OG-Fe(II) oxygenase superfamily; Region: 2OG-FeII_Oxy; pfam03171
1211776003779	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1211776003780	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1211776003781	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
1211776003782	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
1211776003783	THF binding site; other site
1211776003784	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
1211776003785	substrate binding site [chemical binding]; other site
1211776003786	THF binding site; other site
1211776003787	zinc-binding site [ion binding]; other site
1211776003788	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1211776003789	FAD binding site [chemical binding]; other site
1211776003791	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1211776003792	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1211776003794	DNA repair protein RadA; Provisional; Region: PRK11823
1211776003795	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1211776003796	Walker A motif; other site
1211776003797	ATP binding site [chemical binding]; other site
1211776003798	Walker B motif; other site
1211776003799	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1211776003800	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1211776003801	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1211776003802	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1211776003803	P loop; other site
1211776003804	GTP binding site [chemical binding]; other site
1211776003805	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1211776003806	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1211776003807	catalytic residues [active]
1211776003808	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1211776003809	phosphodiesterase; Provisional; Region: PRK12704
1211776003810	KH domain; Region: KH_1; pfam00013
1211776003811	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1211776003812	Zn2+ binding site [ion binding]; other site
1211776003813	Mg2+ binding site [ion binding]; other site
1211776003815	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
1211776003816	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1211776003818	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1211776003820	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
1211776003822	FAD binding domain; Region: FAD_binding_4; pfam01565
1211776003823	glycolate oxidase, subunit GlcD; Region: glcD; TIGR00387
1211776003824	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1211776003825	Peptidase family M23; Region: Peptidase_M23; pfam01551
1211776003826	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1211776003827	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1211776003828	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1211776003829	Lumazine binding domain; Region: Lum_binding; pfam00677
1211776003830	Lumazine binding domain; Region: Lum_binding; pfam00677
1211776003832	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1211776003833	oligomerisation interface [polypeptide binding]; other site
1211776003834	mobile loop; other site
1211776003835	roof hairpin; other site
1211776003836	chaperonin GroL; Region: GroEL; TIGR02348
1211776003837	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1211776003838	ring oligomerisation interface [polypeptide binding]; other site
1211776003839	ATP/Mg binding site [chemical binding]; other site
1211776003840	stacking interactions; other site
1211776003841	hinge regions; other site
1211776003842	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776003843	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1211776003844	dimer interface [polypeptide binding]; other site
1211776003845	phosphorylation site [posttranslational modification]
1211776003846	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776003847	ATP binding site [chemical binding]; other site
1211776003848	Mg2+ binding site [ion binding]; other site
1211776003849	G-X-G motif; other site
1211776003851	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1211776003852	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776003853	active site
1211776003854	phosphorylation site [posttranslational modification]
1211776003855	intermolecular recognition site; other site
1211776003856	dimerization interface [polypeptide binding]; other site
1211776003857	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
1211776003858	DNA binding site [nucleotide binding]
1211776003859	Hemerythrin; Region: Hemerythrin; cd12107
1211776003860	Fe binding site [ion binding]; other site
1211776003861	Predicted DNA-binding protein with an HTH domain [General function prediction only]; Region: COG4710
1211776003862	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776003863	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1211776003864	dimer interface [polypeptide binding]; other site
1211776003865	phosphorylation site [posttranslational modification]
1211776003866	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776003867	ATP binding site [chemical binding]; other site
1211776003868	Mg2+ binding site [ion binding]; other site
1211776003869	G-X-G motif; other site
1211776003871	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1211776003872	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776003873	active site
1211776003874	phosphorylation site [posttranslational modification]
1211776003875	intermolecular recognition site; other site
1211776003876	dimerization interface [polypeptide binding]; other site
1211776003877	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1211776003878	DNA binding site [nucleotide binding]
1211776003879	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
1211776003880	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1211776003881	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1211776003882	protein binding site [polypeptide binding]; other site
1211776003883	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1211776003884	protein binding site [polypeptide binding]; other site
1211776003885	chaperone protein DnaJ; Provisional; Region: PRK14299
1211776003886	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1211776003887	HSP70 interaction site [polypeptide binding]; other site
1211776003888	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1211776003889	substrate binding site [polypeptide binding]; other site
1211776003890	dimer interface [polypeptide binding]; other site
1211776003891	Helix-Turn-Helix DNA binding domain of the HspR transcription regulator; Region: HTH_HspR; cd04766
1211776003892	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1211776003893	DNA binding residues [nucleotide binding]
1211776003894	putative dimer interface [polypeptide binding]; other site
1211776003895	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1211776003896	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1211776003897	Kef-type K+ transport systems, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: Kch; COG1226
1211776003898	TrkA-N domain; Region: TrkA_N; pfam02254
1211776003900	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1211776003901	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776003902	motif II; other site
1211776003903	Glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]; Region: GlyS; COG0751
1211776003904	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1211776003905	Peptidase family M23; Region: Peptidase_M23; pfam01551
1211776003906	Putative S-adenosyl-L-methionine-dependent methyltransferase; Region: Methyltransf_28; pfam02636
1211776003907	exopolyphosphatase; Region: exo_poly_only; TIGR03706
1211776003908	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
1211776003909	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
1211776003910	active site
1211776003911	hydrophilic channel; other site
1211776003912	dimerization interface [polypeptide binding]; other site
1211776003913	catalytic residues [active]
1211776003914	active site lid [active]
1211776003915	4-hydroxythreonine-4-phosphate dehydrogenase; Provisional; Region: pdxA; PRK03946
1211776003916	4-hydroxythreonine-4-phosphate dehydrogenase; Validated; Region: pdxA; PRK03743
1211776003917	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1211776003918	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776003919	putative substrate translocation pore; other site
1211776003921	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
1211776003922	substrate binding site [chemical binding]; other site
1211776003923	active site
1211776003924	Fe-S oxidoreductases [Energy production and conversion]; Region: COG0731
1211776003925	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776003926	FeS/SAM binding site; other site
1211776003928	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1211776003929	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1211776003930	GIY-YIG motif/motif A; other site
1211776003931	active site
1211776003932	catalytic site [active]
1211776003933	putative DNA binding site [nucleotide binding]; other site
1211776003934	metal binding site [ion binding]; metal-binding site
1211776003935	UvrB/uvrC motif; Region: UVR; pfam02151
1211776003936	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1211776003937	GMP synthase; Reviewed; Region: guaA; PRK00074
1211776003938	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1211776003939	AMP/PPi binding site [chemical binding]; other site
1211776003940	candidate oxyanion hole; other site
1211776003941	catalytic triad [active]
1211776003942	potential glutamine specificity residues [chemical binding]; other site
1211776003943	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1211776003944	ATP Binding subdomain [chemical binding]; other site
1211776003945	Ligand Binding sites [chemical binding]; other site
1211776003946	Dimerization subdomain; other site
1211776003947	Protein of unknown function (DUF3584); Region: DUF3584; pfam12128
1211776003948	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
1211776003949	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
1211776003950	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
1211776003951	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
1211776003952	Predicted membrane protein/domain [Function unknown]; Region: COG1714
1211776003954	Organic solvent tolerance protein OstA [Cell envelope biogenesis, outer membrane]; Region: Imp; COG1452
1211776003955	OstA-like protein; Region: OstA; cl00844
1211776003956	Organic solvent tolerance protein; Region: OstA_C; pfam04453
1211776003957	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1211776003958	RNase PH-like 3'-5' exoribonucleases; Region: RNase_PH; cl03114
1211776003959	oligomer interface [polypeptide binding]; other site
1211776003960	RNA binding site [nucleotide binding]; other site
1211776003961	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1211776003962	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1211776003963	RNase E interface [polypeptide binding]; other site
1211776003964	trimer interface [polypeptide binding]; other site
1211776003965	active site
1211776003966	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1211776003967	putative nucleic acid binding region [nucleotide binding]; other site
1211776003968	G-X-X-G motif; other site
1211776003969	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1211776003970	RNA binding site [nucleotide binding]; other site
1211776003971	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
1211776003972	putative active site [active]
1211776003973	4-Oxalocrotonate Tautomerase:  Catalyzes the isomerization of unsaturated ketones. The structure is a homohexamer that is arranged as a trimer of dimers. The hexamer contains six active sites, each formed by residues from three monomers, two from one...; Region: 4Oxalocrotonate_Tautomerase; cd00491
1211776003974	active site 1 [active]
1211776003975	dimer interface [polypeptide binding]; other site
1211776003976	hexamer interface [polypeptide binding]; other site
1211776003977	active site 2 [active]
1211776003978	Protein of unknown function (DUF4230); Region: DUF4230; pfam14014
1211776003980	drug efflux system protein MdtG; Provisional; Region: PRK09874
1211776003981	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776003982	putative substrate translocation pore; other site
1211776003984	Protein-tyrosine-phosphatase [Signal transduction mechanisms]; Region: Wzb; COG0394
1211776003985	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1211776003986	active site
1211776003987	Campylobacter major outer membrane protein; Region: Campylo_MOMP; pfam05538
1211776003988	chaperone protein DnaJ; Provisional; Region: PRK10767
1211776003989	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1211776003990	HSP70 interaction site [polypeptide binding]; other site
1211776003991	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1211776003992	substrate binding site [polypeptide binding]; other site
1211776003993	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1211776003994	Zn binding sites [ion binding]; other site
1211776003995	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1211776003996	dimer interface [polypeptide binding]; other site
1211776003997	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1211776003998	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776003999	active site
1211776004000	phosphorylation site [posttranslational modification]
1211776004001	intermolecular recognition site; other site
1211776004002	dimerization interface [polypeptide binding]; other site
1211776004003	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1211776004004	DNA binding site [nucleotide binding]
1211776004005	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776004006	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1211776004007	dimer interface [polypeptide binding]; other site
1211776004008	phosphorylation site [posttranslational modification]
1211776004009	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776004010	ATP binding site [chemical binding]; other site
1211776004011	Mg2+ binding site [ion binding]; other site
1211776004012	G-X-G motif; other site
1211776004014	recombination protein RecR; Reviewed; Region: recR; PRK00076
1211776004015	RecR protein; Region: RecR; pfam02132
1211776004016	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1211776004017	putative active site [active]
1211776004018	putative metal-binding site [ion binding]; other site
1211776004019	tetramer interface [polypeptide binding]; other site
1211776004020	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
1211776004021	putative substrate-binding site; other site
1211776004022	nickel binding site [ion binding]; other site
1211776004023	Ni/Fe-hydrogenase, b-type cytochrome subunit; Region: CytB-hydogenase; TIGR02125
1211776004024	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1211776004026	Ni,Fe-hydrogenase I large subunit [Energy production and conversion]; Region: HyaB; COG0374
1211776004027	Nickel-dependent hydrogenase; Region: NiFeSe_Hases; pfam00374
1211776004028	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1211776004029	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1211776004030	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
1211776004031	Uncharacterized conserved protein [Function unknown]; Region: COG4121
1211776004032	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1211776004033	AMIN domain; Region: AMIN; pfam11741
1211776004034	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1211776004035	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1211776004036	active site
1211776004037	metal binding site [ion binding]; metal-binding site
1211776004038	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1211776004039	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1211776004040	FMN binding site [chemical binding]; other site
1211776004041	substrate binding site [chemical binding]; other site
1211776004042	putative catalytic residue [active]
1211776004043	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1211776004044	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1211776004045	active site
1211776004046	HIGH motif; other site
1211776004047	dimer interface [polypeptide binding]; other site
1211776004048	KMSKS motif; other site
1211776004049	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1211776004050	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1211776004051	Zn2+ binding site [ion binding]; other site
1211776004052	Mg2+ binding site [ion binding]; other site
1211776004053	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1211776004054	synthetase active site [active]
1211776004055	NTP binding site [chemical binding]; other site
1211776004056	metal binding site [ion binding]; metal-binding site
1211776004057	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1211776004058	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cd02116
1211776004059	DNA-directed RNA polymerase, subunit K/omega [Transcription]; Region: RpoZ; COG1758
1211776004060	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1211776004061	putative nucleotide binding site [chemical binding]; other site
1211776004062	uridine monophosphate binding site [chemical binding]; other site
1211776004063	homohexameric interface [polypeptide binding]; other site
1211776004064	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1211776004065	Peptidase family M23; Region: Peptidase_M23; pfam01551
1211776004067	FtsX-like permease family; Region: FtsX; pfam02687
1211776004069	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1211776004070	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1211776004071	Walker A/P-loop; other site
1211776004072	ATP binding site [chemical binding]; other site
1211776004073	Q-loop/lid; other site
1211776004074	ABC transporter signature motif; other site
1211776004075	Walker B; other site
1211776004076	D-loop; other site
1211776004077	H-loop/switch region; other site
1211776004078	tRNA (guanine-N(7)-)-methyltransferase; Provisional; Region: PRK14121
1211776004079	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1211776004080	Fibronectin type 3 domain-containing protein [General function prediction only]; Region: COG3401
1211776004081	Interdomain contacts; other site
1211776004082	Cytokine receptor motif; other site
1211776004083	Fibronectin type 3 domain; Region: FN3; smart00060
1211776004084	Interdomain contacts; other site
1211776004085	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
1211776004086	Interdomain contacts; other site
1211776004087	Cytokine receptor motif; other site
1211776004088	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1211776004089	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1211776004090	RNA binding surface [nucleotide binding]; other site
1211776004091	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1211776004092	active site
1211776004093	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1211776004095	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1211776004096	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1211776004098	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1211776004099	TrkA-N domain; Region: TrkA_N; pfam02254
1211776004100	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
1211776004101	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776004102	active site
1211776004103	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1211776004104	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1211776004105	putative NAD(P) binding site [chemical binding]; other site
1211776004106	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1211776004107	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1211776004108	active site
1211776004109	HIGH motif; other site
1211776004110	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1211776004111	active site
1211776004112	KMSKS motif; other site
1211776004113	SurA N-terminal domain; Region: SurA_N; pfam09312
1211776004114	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
1211776004116	biotin carboxylase; Validated; Region: PRK08462
1211776004117	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1211776004118	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1211776004119	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1211776004120	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1211776004121	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1211776004122	carboxyltransferase (CT) interaction site; other site
1211776004123	biotinylation site [posttranslational modification]; other site
1211776004124	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1211776004125	trimer interface [polypeptide binding]; other site
1211776004126	active site
1211776004127	UDP-N-acetylglucosamine 4,6-dehydratase; Region: PseB; TIGR03589
1211776004128	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
1211776004129	NAD(P) binding site [chemical binding]; other site
1211776004130	homodimer interface [polypeptide binding]; other site
1211776004131	substrate binding site [chemical binding]; other site
1211776004132	active site
1211776004133	Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WecE; COG0399
1211776004134	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1211776004135	inhibitor-cofactor binding pocket; inhibition site
1211776004136	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776004137	catalytic residue [active]
1211776004138	Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain [General function prediction only]; Region: COG4310
1211776004139	M28 Zn-Peptidases; Region: M28_like_3; cd05644
1211776004140	active site
1211776004141	metal binding site [ion binding]; metal-binding site
1211776004142	Aminoglycoside N3'-acetyltransferase [Defense mechanisms]; Region: COG2746
1211776004143	Aminoglycoside N3'-acetyltransferase [Defense mechanisms]; Region: COG2746
1211776004144	Aminoglycoside N3'-acetyltransferase [Defense mechanisms]; Region: COG2746
1211776004145	Acyl carrier protein [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcpP; COG0236
1211776004146	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1211776004147	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776004148	S-adenosylmethionine binding site [chemical binding]; other site
1211776004149	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase_4; pfam13669
1211776004150	active site
1211776004151	metal binding site [ion binding]; metal-binding site
1211776004152	Predicted enzyme involved in methoxymalonyl-ACP biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FkbH; COG3882
1211776004153	HAD-superfamily phosphatase, subfamily IIIC; Region: HAD-SF-IIIC; TIGR01681
1211776004154	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK12880
1211776004155	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1211776004156	dimer interface [polypeptide binding]; other site
1211776004157	active site
1211776004158	CoA binding pocket [chemical binding]; other site
1211776004159	Phosphopantetheine attachment site; Region: PP-binding; cl09936
1211776004160	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776004161	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776004162	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
1211776004163	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
1211776004164	acyl-activating enzyme (AAE) consensus motif; other site
1211776004165	AMP binding site [chemical binding]; other site
1211776004166	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776004167	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1211776004168	ligand binding site; other site
1211776004169	tetramer interface; other site
1211776004170	pseudaminic acid biosynthesis-associated protein PseG; Region: PseG; TIGR03590
1211776004171	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1211776004172	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776004173	Coenzyme A binding pocket [chemical binding]; other site
1211776004174	imidazole glycerol phosphate synthase subunit HisF; Provisional; Region: PRK01033
1211776004175	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1211776004176	substrate binding site [chemical binding]; other site
1211776004177	glutamase interaction surface [polypeptide binding]; other site
1211776004178	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13152
1211776004179	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1211776004180	putative active site [active]
1211776004181	oxyanion strand; other site
1211776004182	catalytic triad [active]
1211776004183	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1211776004184	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
1211776004185	Ligand Binding Site [chemical binding]; other site
1211776004186	pseudaminic acid synthase; Region: PseI; TIGR03586
1211776004187	NeuB family; Region: NeuB; pfam03102
1211776004188	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1211776004189	NeuB binding interface [polypeptide binding]; other site
1211776004190	putative substrate binding site [chemical binding]; other site
1211776004191	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004192	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
1211776004193	NAD dependent epimerase/dehydratase, LLPSF_EDH_00030 family; Region: EDH_00030; TIGR04180
1211776004194	NAD binding site [chemical binding]; other site
1211776004195	substrate binding site [chemical binding]; other site
1211776004196	active site
1211776004197	aminotransferase, LLPSF_NHT_00031 family; Region: NHT_00031; TIGR04181
1211776004198	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
1211776004199	inhibitor-cofactor binding pocket; inhibition site
1211776004200	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776004201	catalytic residue [active]
1211776004202	Putative Acyltransferase (AT), Left-handed parallel beta-Helix (LbH) domain; This group is composed of mostly uncharacterized proteins containing an N-terminal helical subdomain followed by a LbH domain. The alignment contains 6 turns, each containing...; Region: LbH_AT_putative; cd03360
1211776004203	sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; Region: NeuD_NnaD; TIGR03570
1211776004204	putative trimer interface [polypeptide binding]; other site
1211776004205	putative CoA binding site [chemical binding]; other site
1211776004206	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
1211776004207	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1211776004208	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_III; cd01996
1211776004209	Ligand Binding Site [chemical binding]; other site
1211776004210	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1211776004211	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776004212	S-adenosylmethionine binding site [chemical binding]; other site
1211776004213	N-acetylneuraminate synthase; Region: NeuB_NnaB; TIGR03569
1211776004214	NeuB family; Region: NeuB; pfam03102
1211776004215	C-terminal SAF domain of sialic acid synthetase; Region: SAF_NeuB_like; cd11615
1211776004216	NeuB binding interface [polypeptide binding]; other site
1211776004217	putative substrate binding site [chemical binding]; other site
1211776004218	UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing; Region: NeuC_NnaA; TIGR03568
1211776004219	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1211776004220	active site
1211776004221	homodimer interface [polypeptide binding]; other site
1211776004222	FOG: CBS domain [General function prediction only]; Region: COG0517
1211776004223	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain associated with the NTP (Nucleotidyl transferase) domain downstream. CBS is a small domain originally identified in cystathionine beta-synthase and subsequently...; Region: CBS_pair_NTP_transferase_assoc; cd04607
1211776004224	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1211776004225	NTP_trnasferase_like_2 is a member of the nucleotidyl transferase family; Region: NTP_transferase_like_2; cd06426
1211776004226	Substrate binding site; other site
1211776004227	metal-binding site
1211776004228	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
1211776004229	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1211776004230	CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety; Region: CMP-NeuAc_Synthase; cd02513
1211776004231	ligand binding site; other site
1211776004232	tetramer interface; other site
1211776004233	flagellin modification protein A; Provisional; Region: PRK09186
1211776004234	classical (c) SDR, subgroup 8; Region: SDR_c8; cd08930
1211776004235	putative NAD(P) binding site [chemical binding]; other site
1211776004236	active site
1211776004237	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004239	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004240	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004241	flagellin; Provisional; Region: PRK13589
1211776004242	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1211776004243	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1211776004244	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1211776004245	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1211776004246	flagellin; Reviewed; Region: PRK08411
1211776004247	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1211776004248	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1211776004249	Flagellin hook IN motif; Region: Flagellin_IN; pfam07196
1211776004250	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1211776004251	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004252	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2604
1211776004253	Protein of unknown function (DUF2920); Region: DUF2920; pfam11144
1211776004255	UGMP family protein; Validated; Region: PRK09604
1211776004256	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1211776004257	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cd00596
1211776004258	active site
1211776004259	Zn binding site [ion binding]; other site
1211776004260	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
1211776004261	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1211776004262	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1211776004263	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1211776004264	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1211776004265	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
1211776004267	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
1211776004268	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1211776004269	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1211776004270	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1211776004271	GTP binding site; other site
1211776004272	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
1211776004273	dimerization interface [polypeptide binding]; other site
1211776004274	substrate binding site [chemical binding]; other site
1211776004275	active site
1211776004276	calcium binding site [ion binding]; other site
1211776004277	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1211776004278	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1211776004279	ABC-ATPase subunit  interface; other site
1211776004280	dimer interface [polypeptide binding]; other site
1211776004281	putative PBP binding regions; other site
1211776004283	ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism]; Region: CeuC; COG4605
1211776004284	ABC-ATPase subunit  interface; other site
1211776004285	dimer interface [polypeptide binding]; other site
1211776004286	putative PBP binding regions; other site
1211776004288	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1211776004289	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1211776004290	Walker A/P-loop; other site
1211776004291	ATP binding site [chemical binding]; other site
1211776004292	Q-loop/lid; other site
1211776004293	ABC transporter signature motif; other site
1211776004294	Walker B; other site
1211776004295	D-loop; other site
1211776004296	H-loop/switch region; other site
1211776004297	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1211776004298	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1211776004299	putative ligand binding residues [chemical binding]; other site
1211776004301	Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit [Inorganic ion transport and metabolism]; Region: NrfA; COG3303
1211776004303	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
1211776004304	cytochrome c-type protein NapC; Provisional; Region: PRK10617; cl17554
1211776004306	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
1211776004307	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
1211776004308	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
1211776004309	Catalytic C-terminal domain, first repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C1_like; cd09165
1211776004310	putative domain interface [polypeptide binding]; other site
1211776004311	putative active site [active]
1211776004312	catalytic site [active]
1211776004313	Catalytic C-terminal domain, second repeat, of Pseudomonas aeruginosa polyphosphate kinase 1 and similar proteins; Region: PLDc_PaPPK1_C2_like; cd09168
1211776004314	putative domain interface [polypeptide binding]; other site
1211776004315	putative active site [active]
1211776004316	catalytic site [active]
1211776004317	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1211776004318	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776004319	Walker A motif; other site
1211776004320	ATP binding site [chemical binding]; other site
1211776004321	Walker B motif; other site
1211776004322	arginine finger; other site
1211776004323	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1211776004324	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1211776004325	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1211776004327	fumarate hydratase; Reviewed; Region: fumC; PRK00485
1211776004328	Class II fumarases; Region: Fumarase_classII; cd01362
1211776004329	active site
1211776004330	tetramer interface [polypeptide binding]; other site
1211776004331	Peptidase S8 family domain in Autotransporter serine proteases; Region: Peptidases_S8_Autotransporter_serine_protease_like; cd04848
1211776004332	catalytic triad [active]
1211776004333	putative active site [active]
1211776004334	autotransporter-associated beta strand repeat; Region: autotrns_rpt; TIGR02601
1211776004335	Autotransporter beta-domain; Region: Autotransporter; pfam03797
1211776004336	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1211776004337	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1211776004338	glutaminase active site [active]
1211776004339	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1211776004340	dimer interface [polypeptide binding]; other site
1211776004341	active site
1211776004342	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1211776004343	dimer interface [polypeptide binding]; other site
1211776004344	active site
1211776004345	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1211776004346	hypothetical protein; Provisional; Region: PRK08444
1211776004347	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776004348	FeS/SAM binding site; other site
1211776004349	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1211776004350	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1211776004352	Predicted phosphoribosyltransferases [General function prediction only]; Region: COG2236
1211776004353	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1211776004354	active site
1211776004355	Surface lipoprotein [Cell envelope biogenesis, outer membrane]; Region: VacJ; COG2853
1211776004356	ABC-type transport system involved in resistance to organic solvents, auxiliary component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2D; COG2854
1211776004357	Predicted exporters of the RND superfamily [General function prediction only]; Region: COG1033
1211776004358	6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein; Region: PTPS_related; pfam10131
1211776004360	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1211776004361	active site
1211776004362	dimerization interface [polypeptide binding]; other site
1211776004363	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776004364	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1211776004365	putative substrate translocation pore; other site
1211776004367	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819
1211776004368	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1211776004369	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1211776004370	seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474
1211776004371	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1211776004372	Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276
1211776004373	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1211776004374	G1 box; other site
1211776004375	putative GEF interaction site [polypeptide binding]; other site
1211776004376	GTP/Mg2+ binding site [chemical binding]; other site
1211776004377	Switch I region; other site
1211776004378	G2 box; other site
1211776004379	G3 box; other site
1211776004380	Switch II region; other site
1211776004381	G4 box; other site
1211776004382	G5 box; other site
1211776004383	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1211776004384	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1211776004385	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
1211776004386	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1211776004388	flavodoxin FldA; Validated; Region: PRK09267
1211776004389	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4378
1211776004390	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1211776004391	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1211776004392	tetramer interface [polypeptide binding]; other site
1211776004393	heme binding pocket [chemical binding]; other site
1211776004394	NADPH binding site [chemical binding]; other site
1211776004395	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
1211776004396	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
1211776004397	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
1211776004398	YheO-like PAS domain; Region: PAS_6; pfam08348
1211776004399	HTH domain; Region: HTH_22; pfam13309
1211776004400	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1211776004401	homotrimer interaction site [polypeptide binding]; other site
1211776004402	putative active site [active]
1211776004406	cystathionine beta-lyase, bacterial; Region: cysta_beta_ly_B; TIGR01324
1211776004407	cystathionine beta-lyase, bacterial; Region: cysta_beta_ly_B; TIGR01324
1211776004408	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1211776004409	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1211776004410	catalytic residue [active]
1211776004411	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
1211776004412	prokaryotic 3-carboxy-cis,cis-muconate cycloisomerase (CMLE)_like; Region: pCLME; cd01597
1211776004413	tetramer interface [polypeptide binding]; other site
1211776004414	active site
1211776004416	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
1211776004417	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1211776004418	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1211776004419	G1 box; other site
1211776004420	GTP/Mg2+ binding site [chemical binding]; other site
1211776004421	Switch I region; other site
1211776004422	G2 box; other site
1211776004423	G3 box; other site
1211776004424	Switch II region; other site
1211776004425	G4 box; other site
1211776004426	G5 box; other site
1211776004427	Nucleoside recognition; Region: Gate; pfam07670
1211776004428	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1211776004429	Nucleoside recognition; Region: Gate; pfam07670
1211776004431	Ni,Fe-hydrogenase I small subunit [Energy production and conversion]; Region: HyaA; COG1740
1211776004432	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
1211776004433	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08415
1211776004434	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1211776004435	NAD binding site [chemical binding]; other site
1211776004436	homotetramer interface [polypeptide binding]; other site
1211776004437	homodimer interface [polypeptide binding]; other site
1211776004438	substrate binding site [chemical binding]; other site
1211776004439	active site
1211776004440	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1211776004441	triosephosphate isomerase; Provisional; Region: PRK14565
1211776004442	substrate binding site [chemical binding]; other site
1211776004443	dimer interface [polypeptide binding]; other site
1211776004444	catalytic triad [active]
1211776004445	Phosphoglycerate kinase; Region: PGK; pfam00162
1211776004446	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1211776004447	substrate binding site [chemical binding]; other site
1211776004448	hinge regions; other site
1211776004449	ADP binding site [chemical binding]; other site
1211776004450	catalytic site [active]
1211776004451	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1211776004452	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1211776004453	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1211776004454	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1211776004455	nicotinate (nicotinamide) nucleotide adenylyltransferase; Region: TIGR00482
1211776004456	active site
1211776004457	(T/H)XGH motif; other site
1211776004458	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
1211776004459	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
1211776004460	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1211776004461	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
1211776004462	active site
1211776004463	substrate binding site [chemical binding]; other site
1211776004464	metal binding site [ion binding]; metal-binding site
1211776004465	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK08455
1211776004467	Phosphopantetheinyl transferase (holo-ACP synthase) [Lipid metabolism]; Region: AcpS; COG0736
1211776004469	Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism]; Region: CypX; COG2124
1211776004470	Cytochrome P450; Region: p450; cl12078
1211776004472	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsS; COG3562
1211776004473	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; pfam05159
1211776004475	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsC; COG3563
1211776004476	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1211776004477	ligand-binding site [chemical binding]; other site
1211776004478	Phosphocholine cytidylyltransferases catalyze the synthesis of CDP-choline; Region: PC_cytidylyltransferase; cd02523
1211776004479	active site
1211776004480	metal-binding site
1211776004481	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1211776004482	Type 1 glutamine amidotransferase (GATase1)-like domain; Region: GAT_1; cl00020
1211776004483	conserved cys residue [active]
1211776004484	hypothetical protein; Provisional; Region: PRK05849
1211776004485	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1211776004486	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1211776004487	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776004488	S-adenosylmethionine binding site [chemical binding]; other site
1211776004489	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1211776004490	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776004491	S-adenosylmethionine binding site [chemical binding]; other site
1211776004492	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
1211776004493	Protein of unknown function (DUF2972); Region: DUF2972; pfam11186
1211776004494	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure...; Region: GCD1; COG1208
1211776004495	WcbM_like is a subfamily of nucleotidyl transferases; Region: NTP_transferase_WcbM_like; cd06915
1211776004496	Substrate binding site; other site
1211776004497	Mg++ binding site; other site
1211776004498	metal-binding site
1211776004499	Mg++ binding site; other site
1211776004500	metal-binding site
1211776004501	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
1211776004502	dimer interface [polypeptide binding]; other site
1211776004503	active site
1211776004504	Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only]; Region: COG2605
1211776004505	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1211776004506	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1211776004507	Methyltransferase FkbM domain; Region: Methyltransf_21; cl17387
1211776004508	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1211776004509	extended (e) SDRs; Region: SDR_e; cd08946
1211776004510	NAD(P) binding site [chemical binding]; other site
1211776004511	active site
1211776004512	substrate binding site [chemical binding]; other site
1211776004513	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
1211776004514	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
1211776004515	NADP binding site [chemical binding]; other site
1211776004516	active site
1211776004517	putative substrate binding site [chemical binding]; other site
1211776004518	dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfbC; COG1898
1211776004519	GDP-fucose protein O-fucosyltransferase and related proteins; Region: O-FucT_like; cl16914
1211776004520	GDP-Fucose binding site [chemical binding]; other site
1211776004521	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
1211776004522	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1211776004523	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG5610
1211776004524	haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; Region: HAD-SF-IA-v1; TIGR01549
1211776004525	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776004526	FeS/SAM binding site; other site
1211776004527	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776004528	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1211776004529	active site
1211776004530	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1211776004531	HAD-superfamily subfamily IB hydrolase, TIGR01490; Region: HAD-SF-IB-hyp1
1211776004532	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1211776004533	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1211776004534	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776004535	homodimer interface [polypeptide binding]; other site
1211776004536	catalytic residue [active]
1211776004537	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1211776004538	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1211776004539	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776004540	homodimer interface [polypeptide binding]; other site
1211776004541	catalytic residue [active]
1211776004542	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1211776004543	active site
1211776004544	TupA-like ATPgrasp; Region: ATPgrasp_TupA; pfam14305
1211776004545	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
1211776004546	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1211776004547	UDP-galactopyranose mutase; Region: GLF; pfam03275
1211776004548	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1211776004549	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776004550	active site
1211776004552	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
1211776004553	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1211776004554	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1211776004555	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1211776004556	Predicted glycosyltransferase involved in capsule biosynthesis [Cell envelope biogenesis, outer membrane]; Region: COG4092
1211776004557	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1211776004558	active site
1211776004559	N-terminal domain of galactosyltransferase; Region: Glyco_transf_7C; cl17476
1211776004560	KpsF/GutQ family protein; Region: kpsF; TIGR00393
1211776004561	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
1211776004562	putative active site [active]
1211776004563	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
1211776004564	Periplasmic protein involved in polysaccharide export, contains    SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis]; Region: Wza; COG1596
1211776004565	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
1211776004566	SLBB domain; Region: SLBB; pfam10531
1211776004567	Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane]; Region: KpsE; COG3524
1211776004569	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1211776004570	ATP-binding cassette component of polysaccharide transport system; Region: ABC_KpsT_Wzt; cd03220
1211776004571	Walker A/P-loop; other site
1211776004572	ATP binding site [chemical binding]; other site
1211776004573	Q-loop/lid; other site
1211776004574	ABC transporter signature motif; other site
1211776004575	Walker B; other site
1211776004576	D-loop; other site
1211776004577	H-loop/switch region; other site
1211776004578	ABC-type polysaccharide/polyol phosphate export systems, permease component [Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: TagG; COG1682
1211776004579	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1211776004581	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3787
1211776004582	dUTPase; Region: dUTPase_2; pfam08761
1211776004583	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in dimeric 2-Deoxyuridine 5'-triphosphate nucleotidohydrolase and similar proteins; Region: NTP-PPase_dUTPase; cd11527
1211776004584	active site
1211776004585	homodimer interface [polypeptide binding]; other site
1211776004586	metal binding site [ion binding]; metal-binding site
1211776004587	Etoposide-induced protein 2.4 (EI24); Region: EI24; pfam07264
1211776004589	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1211776004590	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1211776004591	Ligand Binding Site [chemical binding]; other site
1211776004592	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1211776004593	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1211776004594	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776004595	FeS/SAM binding site; other site
1211776004596	peptide chain release factor 2; Validated; Region: prfB; PRK00578
1211776004597	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1211776004598	RF-1 domain; Region: RF-1; pfam00472
1211776004599	tRNA pseudouridine synthase D; Reviewed; Region: truD; PRK00984
1211776004600	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
1211776004601	Permutation of conserved domain; other site
1211776004602	active site
1211776004603	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1211776004604	thiamine monophosphate kinase; Provisional; Region: PRK05731
1211776004605	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
1211776004606	ATP binding site [chemical binding]; other site
1211776004607	dimerization interface [polypeptide binding]; other site
1211776004608	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
1211776004609	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1211776004610	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1211776004611	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
1211776004612	flagellar basal body P-ring protein; Reviewed; Region: flgI; cl14622
1211776004613	Rod binding protein; Region: Rod-binding; cl01626
1211776004614	FlgN protein; Region: FlgN; pfam05130
1211776004615	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08471
1211776004616	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1211776004617	Protein of unknown function (DUF2400); Region: DUF2400; pfam09674
1211776004618	hypothetical protein; Provisional; Region: PRK10621
1211776004619	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1211776004624	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
1211776004625	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1211776004626	Walker A motif; other site
1211776004627	ATP binding site [chemical binding]; other site
1211776004628	Walker B motif; other site
1211776004630	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1211776004631	AAA domain; Region: AAA_22; pfam13401
1211776004632	Walker A motif; other site
1211776004633	ATP binding site [chemical binding]; other site
1211776004634	Walker B motif; other site
1211776004635	arginine finger; other site
1211776004636	pilus (MSHA type) biogenesis protein MshL; Region: pilus_MshL; TIGR02519
1211776004637	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
1211776004638	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1211776004639	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1211776004640	dimer interface [polypeptide binding]; other site
1211776004641	PYR/PP interface [polypeptide binding]; other site
1211776004642	TPP binding site [chemical binding]; other site
1211776004643	substrate binding site [chemical binding]; other site
1211776004644	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1211776004645	Domain of unknown function; Region: EKR; pfam10371
1211776004646	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1211776004647	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1211776004648	TPP-binding site [chemical binding]; other site
1211776004649	dimer interface [polypeptide binding]; other site
1211776004650	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
1211776004651	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776004652	motif II; other site
1211776004653	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1211776004654	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
1211776004655	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1211776004656	ligand binding site [chemical binding]; other site
1211776004657	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1211776004658	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1211776004659	23S rRNA interface [nucleotide binding]; other site
1211776004660	L3 interface [polypeptide binding]; other site
1211776004661	Part of AAA domain; Region: AAA_19; pfam13245
1211776004662	putative recombination protein RecB; Provisional; Region: PRK13909
1211776004663	Family description; Region: UvrD_C_2; pfam13538
1211776004664	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1211776004665	Inactivated superfamily I helicase [DNA replication, recombination, and repair]; Region: COG3893
1211776004666	RecB family exonuclease [DNA replication, recombination, and repair]; Region: COG2887
1211776004667	FixH; Region: FixH; pfam05751
1211776004669	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1211776004672	Family of unknown function (DUF4006); Region: DUF4006; pfam13179
1211776004674	cytochrome c oxidase, cbb3-type, subunit III; Region: ccoP; TIGR00782
1211776004675	Cytochrome c; Region: Cytochrom_C; cl11414
1211776004676	Cytochrome C oxidase, cbb3-type, subunit III; Region: Cytochrome_CBB3; pfam13442
1211776004678	cytochrome c oxidase, cbb3-type, CcoQ subunit, epsilon-Proteobacterial; Region: cbb3_Q_epsi; TIGR02736
1211776004680	Cbb3-type cytochrome oxidase, cytochrome c subunit [Energy production and conversion]; Region: CcoO; COG2993
1211776004681	cbb3-type cytochrome c oxidase subunit II; Provisional; Region: PRK14487
1211776004683	cbb3-type cytochrome c oxidase subunit I; Provisional; Region: PRK14488
1211776004684	Low-spin heme binding site [chemical binding]; other site
1211776004685	Cytochrome C and Quinol oxidase polypeptide I; Region: COX1; pfam00115
1211776004686	D-pathway; other site
1211776004687	Putative water exit pathway; other site
1211776004688	Binuclear center (active site) [active]
1211776004689	K-pathway; other site
1211776004690	Putative proton exit pathway; other site
1211776004692	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1211776004693	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776004694	active site
1211776004695	phosphorylation site [posttranslational modification]
1211776004696	intermolecular recognition site; other site
1211776004697	dimerization interface [polypeptide binding]; other site
1211776004698	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1211776004699	DNA binding site [nucleotide binding]
1211776004700	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1211776004701	PAS domain; Region: PAS_9; pfam13426
1211776004702	putative active site [active]
1211776004703	heme pocket [chemical binding]; other site
1211776004704	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1211776004705	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1211776004706	ATP binding site [chemical binding]; other site
1211776004707	Mg2+ binding site [ion binding]; other site
1211776004708	G-X-G motif; other site
1211776004709	Uncharacterized conserved protein [Function unknown]; Region: COG2836
1211776004711	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1211776004712	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1211776004713	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1211776004714	catalytic site [active]
1211776004715	subunit interface [polypeptide binding]; other site
1211776004716	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2952
1211776004717	Uncharacterized conserved protein [Function unknown]; Region: COG3334
1211776004718	Flagellar FliJ protein; Region: FliJ; pfam02050
1211776004719	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1211776004720	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1211776004721	GDP-binding site [chemical binding]; other site
1211776004722	ACT binding site; other site
1211776004723	IMP binding site; other site
1211776004724	putative inner membrane protein; Provisional; Region: PRK11099
1211776004725	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1211776004727	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
1211776004728	CPxP  motif; other site
1211776004729	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
1211776004730	Na binding site [ion binding]; other site
1211776004732	Proline dehydrogenase [Amino acid transport and metabolism]; Region: PutA; COG0506
1211776004733	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
1211776004734	Aldehyde dehydrogenase family; Region: Aldedh; pfam00171
1211776004735	Glutamate binding site [chemical binding]; other site
1211776004736	NAD binding site [chemical binding]; other site
1211776004737	catalytic residues [active]
1211776004738	Selenophosphate synthase [Amino acid transport and metabolism]; Region: SelD; COG0709
1211776004739	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1211776004740	dimerization interface [polypeptide binding]; other site
1211776004741	putative ATP binding site [chemical binding]; other site
1211776004742	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
1211776004743	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
1211776004744	CPxP  motif; other site
1211776004745	Cache domain; Region: Cache_1; pfam02743
1211776004746	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776004747	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776004748	dimer interface [polypeptide binding]; other site
1211776004749	putative CheW interface [polypeptide binding]; other site
1211776004751	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
1211776004752	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
1211776004753	Cytochrome b subunit of formate dehydrogenase [Energy production and conversion]; Region: FdnI; COG2864
1211776004754	formate dehydrogenase, gamma subunit; Region: formate-DH-gamm; TIGR01583
1211776004756	Fe-S-cluster-containing hydrogenase components 1 [Energy production and conversion]; Region: HybA; COG0437
1211776004758	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
1211776004759	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
1211776004760	carboxynorspermidine decarboxylase; Region: nspC; TIGR01047
1211776004761	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Carboxynorspermidine Decarboxylase; Region: PLPDE_III_CANSDC; cd06829
1211776004762	dimer interface [polypeptide binding]; other site
1211776004763	active site
1211776004764	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1211776004765	catalytic residues [active]
1211776004766	substrate binding site [chemical binding]; other site
1211776004767	Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: SufI; COG2132
1211776004768	Multicopper oxidase; Region: Cu-oxidase_3; pfam07732
1211776004769	Multicopper oxidase; Region: Cu-oxidase; pfam00394
1211776004770	Multicopper oxidase; Region: Cu-oxidase_2; pfam07731
1211776004771	ThiS family; Region: ThiS; pfam02597
1211776004772	charged pocket; other site
1211776004773	hydrophobic patch; other site
1211776004774	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
1211776004775	MoaE homodimer interface [polypeptide binding]; other site
1211776004776	MoaD interaction [polypeptide binding]; other site
1211776004777	active site residues [active]
1211776004778	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1211776004779	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1211776004780	dimer interface [polypeptide binding]; other site
1211776004781	putative functional site; other site
1211776004782	putative MPT binding site; other site
1211776004783	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09638
1211776004784	CRISPR/Cas system-associated protein Cas1; Region: Cas1_II; cd09720
1211776004785	Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms]; Region: COG3513
1211776004786	CRISPR/Cas system-associated protein Cas9; Region: Csn1; cd09643
1211776004790	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
1211776004791	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
1211776004792	dimerization interface [polypeptide binding]; other site
1211776004793	putative ATP binding site [chemical binding]; other site
1211776004794	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1211776004795	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1211776004796	CoA-binding site [chemical binding]; other site
1211776004797	ATP-binding [chemical binding]; other site
1211776004798	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
1211776004799	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1211776004800	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1211776004801	Uncharacterized FlgJ-related protein [General function prediction only]; Region: Bax; COG2992
1211776004802	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; pfam01832
1211776004803	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG1373
1211776004804	AAA domain; Region: AAA_14; pfam13173
1211776004805	DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism]; Region: Dps; COG0783
1211776004806	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
1211776004807	dimerization interface [polypeptide binding]; other site
1211776004808	DPS ferroxidase diiron center [ion binding]; other site
1211776004809	ion pore; other site
1211776004810	DPS ferroxidase diiron center [ion binding]; other site
1211776004811	glucose-6-phosphate isomerase; Provisional; Region: PRK03868
1211776004812	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1211776004813	active site
1211776004814	dimer interface [polypeptide binding]; other site
1211776004815	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1211776004816	dimer interface [polypeptide binding]; other site
1211776004817	active site
1211776004818	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1211776004819	active site
1211776004820	tetramer interface; other site
1211776004821	acetyl-CoA synthetase; Provisional; Region: PRK00174
1211776004822	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
1211776004823	active site
1211776004824	CoA binding site [chemical binding]; other site
1211776004825	acyl-activating enzyme (AAE) consensus motif; other site
1211776004826	AMP binding site [chemical binding]; other site
1211776004827	acetate binding site [chemical binding]; other site
1211776004828	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1211776004829	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776004830	Walker A/P-loop; other site
1211776004831	ATP binding site [chemical binding]; other site
1211776004832	Q-loop/lid; other site
1211776004833	ABC transporter signature motif; other site
1211776004834	Walker B; other site
1211776004835	D-loop; other site
1211776004836	H-loop/switch region; other site
1211776004837	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776004838	dimer interface [polypeptide binding]; other site
1211776004839	conserved gate region; other site
1211776004840	putative PBP binding loops; other site
1211776004841	ABC-ATPase subunit interface; other site
1211776004843	ABC-type tungstate transport system, permease component [Coenzyme metabolism]; Region: TupB; COG2998
1211776004844	PBP superfamily domain; Region: PBP_like_2; pfam12849
1211776004845	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1211776004846	putative active site [active]
1211776004847	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1211776004848	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1211776004849	Allophanate hydrolase subunit 2 [Amino acid transport and metabolism]; Region: DUR1; COG1984
1211776004850	EamA-like transporter family; Region: EamA; pfam00892
1211776004852	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
1211776004853	Predicted transcriptional regulators [Transcription]; Region: COG1733
1211776004854	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1211776004855	Bacterial lipocalin [Cell envelope biogenesis, outer membrane]; Region: Blc; COG3040
1211776004856	Lipocalin-like domain; Region: Lipocalin_2; pfam08212
1211776004857	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
1211776004858	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
1211776004859	putative NAD(P) binding site [chemical binding]; other site
1211776004860	putative substrate binding site [chemical binding]; other site
1211776004861	catalytic Zn binding site [ion binding]; other site
1211776004862	structural Zn binding site [ion binding]; other site
1211776004863	dimer interface [polypeptide binding]; other site
1211776004864	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1211776004865	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1211776004866	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1211776004867	ATP binding site [chemical binding]; other site
1211776004868	putative Mg++ binding site [ion binding]; other site
1211776004869	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
1211776004870	AAA domain; Region: AAA_21; pfam13304
1211776004871	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776004872	ABC transporter signature motif; other site
1211776004873	Walker B; other site
1211776004874	D-loop; other site
1211776004875	H-loop/switch region; other site
1211776004876	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1211776004877	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1211776004878	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1211776004879	Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen [Transcription]; Region: COG2865
1211776004880	Divergent AAA domain; Region: AAA_4; pfam04326
1211776004881	ATP-dependent DNA helicase recG C-terminal; Region: HATPase_c_4; pfam13749
1211776004882	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1211776004883	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1211776004884	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1211776004885	biliverdin IX beta reductase (BVR-B, aka flavin reductase)-like proteins; atypical (a) SDRs; Region: BVR-B_like_SDR_a; cd05244
1211776004886	NADH(P)-binding; Region: NAD_binding_10; pfam13460
1211776004887	NAD binding site [chemical binding]; other site
1211776004888	substrate binding site [chemical binding]; other site
1211776004889	putative active site [active]
1211776004890	Predicted transcriptional regulators [Transcription]; Region: COG1733
1211776004891	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1211776004892	dimerization interface [polypeptide binding]; other site
1211776004893	putative DNA binding site [nucleotide binding]; other site
1211776004894	putative Zn2+ binding site [ion binding]; other site
1211776004898	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1211776004899	dimerization interface [polypeptide binding]; other site
1211776004900	putative DNA binding site [nucleotide binding]; other site
1211776004901	putative Zn2+ binding site [ion binding]; other site
1211776004902	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1211776004903	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1211776004904	DNA binding residues [nucleotide binding]
1211776004905	putative dimer interface [polypeptide binding]; other site
1211776004906	Cache domain; Region: Cache_1; pfam02743
1211776004907	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1211776004908	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1211776004909	dimer interface [polypeptide binding]; other site
1211776004910	putative CheW interface [polypeptide binding]; other site
1211776004912	Vi polysaccharide biosynthesis protein TviE; Provisional; Region: PRK15490
1211776004913	NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; Region: NuoN; COG1007
1211776004914	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1211776004916	proton-translocating NADH-quinone oxidoreductase, chain M; Region: NDH_I_M; TIGR01972
1211776004917	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1211776004919	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
1211776004920	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
1211776004921	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
1211776004923	NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) [Energy production and conversion]; Region: NuoK; COG0713
1211776004925	NADH dehydrogenase subunit J; Provisional; Region: PRK06433
1211776004926	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
1211776004928	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
1211776004929	4Fe-4S binding domain; Region: Fer4; cl02805
1211776004930	4Fe-4S binding domain; Region: Fer4; pfam00037
1211776004931	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
1211776004933	NADH dehydrogenase subunit G; Validated; Region: PRK08493
1211776004934	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1211776004935	catalytic loop [active]
1211776004936	iron binding site [ion binding]; other site
1211776004937	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1211776004938	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1211776004939	NADH dehydrogenase subunit D; Validated; Region: PRK06075
1211776004940	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
1211776004941	NADH dehydrogenase subunit C; Provisional; Region: PRK08491
1211776004942	NADH (or F420H2) dehydrogenase, subunit C; Region: NuoC_fam; TIGR01961
1211776004943	NADH dehydrogenase subunit B; Validated; Region: PRK06411
1211776004944	NADH dehydrogenase subunit A; Validated; Region: PRK08489
1211776004946	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1211776004947	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1211776004948	Walker A/P-loop; other site
1211776004949	ATP binding site [chemical binding]; other site
1211776004950	Q-loop/lid; other site
1211776004951	ABC transporter signature motif; other site
1211776004952	Walker B; other site
1211776004953	D-loop; other site
1211776004954	H-loop/switch region; other site
1211776004955	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1211776004956	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1211776004957	Walker A/P-loop; other site
1211776004958	ATP binding site [chemical binding]; other site
1211776004959	Q-loop/lid; other site
1211776004960	ABC transporter signature motif; other site
1211776004961	Walker B; other site
1211776004962	D-loop; other site
1211776004963	H-loop/switch region; other site
1211776004964	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1211776004965	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1211776004966	putative PBP binding loops; other site
1211776004967	ABC-ATPase subunit interface; other site
1211776004969	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1211776004970	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1211776004972	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1211776004973	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
1211776004974	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1211776004975	FAD binding domain; Region: FAD_binding_4; pfam01565
1211776004976	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1211776004977	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1211776004978	heme-binding site [chemical binding]; other site
1211776004979	ABC-type siderophore export system, fused ATPase and permease components [Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism]; Region: PvdE; COG4615
1211776004980	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1211776004981	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1211776004982	Walker A/P-loop; other site
1211776004983	ATP binding site [chemical binding]; other site
1211776004984	Q-loop/lid; other site
1211776004985	ABC transporter signature motif; other site
1211776004986	Walker B; other site
1211776004987	D-loop; other site
1211776004988	H-loop/switch region; other site
1211776004990	metabolite-proton symporter; Region: 2A0106; TIGR00883
1211776004991	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776004992	putative substrate translocation pore; other site
1211776004994	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1211776004995	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1211776004996	rRNA binding site [nucleotide binding]; other site
1211776004997	predicted 30S ribosome binding site; other site
1211776004998	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
1211776004999	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1211776005000	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1211776005001	30S ribosomal protein S11; Validated; Region: PRK05309
1211776005002	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1211776005003	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1211776005004	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1211776005005	RNA binding surface [nucleotide binding]; other site
1211776005006	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1211776005007	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1211776005008	alphaNTD homodimer interface [polypeptide binding]; other site
1211776005009	alphaNTD - beta interaction site [polypeptide binding]; other site
1211776005010	alphaNTD - beta' interaction site [polypeptide binding]; other site
1211776005011	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1211776005012	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1211776005013	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
1211776005014	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
1211776005015	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
1211776005016	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
1211776005017	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1211776005018	NAD binding site [chemical binding]; other site
1211776005019	dimerization interface [polypeptide binding]; other site
1211776005020	product binding site; other site
1211776005021	substrate binding site [chemical binding]; other site
1211776005022	zinc binding site [ion binding]; other site
1211776005023	catalytic residues [active]
1211776005024	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
1211776005025	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1211776005026	active site
1211776005027	motif I; other site
1211776005028	motif II; other site
1211776005029	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1211776005030	putative active site pocket [active]
1211776005031	4-fold oligomerization interface [polypeptide binding]; other site
1211776005032	metal binding residues [ion binding]; metal-binding site
1211776005033	3-fold/trimer interface [polypeptide binding]; other site
1211776005034	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13170
1211776005035	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1211776005036	putative active site [active]
1211776005037	oxyanion strand; other site
1211776005038	catalytic triad [active]
1211776005039	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1211776005040	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1211776005041	catalytic residues [active]
1211776005042	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2958
1211776005043	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1211776005044	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1211776005045	substrate binding site [chemical binding]; other site
1211776005046	glutamase interaction surface [polypeptide binding]; other site
1211776005047	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
1211776005048	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
1211776005049	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1211776005050	metal binding site [ion binding]; metal-binding site
1211776005051	Tetrahydrodipicolinate N-succinyltransferase [Amino acid transport and metabolism]; Region: DapD; COG2171
1211776005052	Putative 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (THP succinyltransferase), C-terminal left-handed parallel alpha-helix (LbH) domain: This group is composed of mostly uncharacterized proteins containing an N-terminal...; Region: LbH_THP_succinylT_putative; cd04649
1211776005053	putative trimer interface [polypeptide binding]; other site
1211776005054	putative CoA binding site [chemical binding]; other site
1211776005055	antiporter inner membrane protein; Provisional; Region: PRK11670
1211776005056	Domain of unknown function DUF59; Region: DUF59; pfam01883
1211776005057	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1211776005058	bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein; Provisional; Region: ispDF; PRK09382
1211776005059	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1211776005060	substrate binding site; other site
1211776005061	dimer interface; other site
1211776005062	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1211776005063	homotrimer interaction site [polypeptide binding]; other site
1211776005064	zinc binding site [ion binding]; other site
1211776005065	CDP-binding sites; other site
1211776005066	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1211776005067	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1211776005068	active site
1211776005069	intermolecular recognition site; other site
1211776005070	dimerization interface [polypeptide binding]; other site
1211776005071	ATP sulfurylase (sulfate adenylyltransferase) [Inorganic ion transport and metabolism]; Region: MET3; COG2046
1211776005072	ATP-sulfurylase; Region: ATP-sulfurylase; pfam01747
1211776005073	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1211776005074	tetramer interfaces [polypeptide binding]; other site
1211776005075	binuclear metal-binding site [ion binding]; other site
1211776005077	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1211776005078	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1211776005079	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1211776005080	RF-1 domain; Region: RF-1; pfam00472
1211776005081	Protein of unknown function (DUF2470); Region: DUF2470; pfam10615
1211776005082	heme oxygenase, HugZ family; Region: heme_ox_HugZ; TIGR04109
1211776005083	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1211776005084	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
1211776005085	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
1211776005086	N-terminal plug; other site
1211776005087	ligand-binding site [chemical binding]; other site
1211776005088	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1211776005089	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1211776005090	ABC-ATPase subunit  interface; other site
1211776005091	dimer interface [polypeptide binding]; other site
1211776005092	putative PBP binding regions; other site
1211776005094	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1211776005095	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1211776005096	Walker A/P-loop; other site
1211776005097	ATP binding site [chemical binding]; other site
1211776005098	Q-loop/lid; other site
1211776005099	ABC transporter signature motif; other site
1211776005100	Walker B; other site
1211776005101	D-loop; other site
1211776005102	H-loop/switch region; other site
1211776005103	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
1211776005104	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1211776005105	putative binding site residues; other site
1211776005106	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776005107	FeS/SAM binding site; other site
1211776005108	Domain of unknown function (DUF4008); Region: DUF4008; pfam13186
1211776005109	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
1211776005110	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776005111	putative substrate translocation pore; other site
1211776005113	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
1211776005114	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1211776005115	minor groove reading motif; other site
1211776005116	helix-hairpin-helix signature motif; other site
1211776005117	substrate binding pocket [chemical binding]; other site
1211776005118	active site
1211776005120	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1211776005121	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1211776005122	catalytic motif [active]
1211776005123	Zn binding site [ion binding]; other site
1211776005124	RibD C-terminal domain; Region: RibD_C; cl17279
1211776005126	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
1211776005127	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1211776005128	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
1211776005129	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
1211776005130	threonine/serine transporter TdcC; Provisional; Region: PRK13629; cl17672
1211776005132	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1211776005133	Protein of unknown function (DUF2874); Region: DUF2874; pfam11396
1211776005134	Domain of unknown function (DUF4261); Region: DUF4261; pfam14080
1211776005135	tonB-system energizer ExbB, group 2; Region: exbB2; TIGR02805
1211776005137	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
1211776005138	TonB system transport protein ExbD, group 2; Region: ExbD_2; TIGR02804
1211776005140	Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane]; Region: TonB; COG0810
1211776005141	Gram-negative bacterial tonB protein; Region: TonB; pfam03544
1211776005143	Protein of unknown function (DUF3135); Region: DUF3135; pfam11333
1211776005144	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1211776005145	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1211776005146	Ligand Binding Site [chemical binding]; other site
1211776005147	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1211776005148	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1211776005149	Tetramer interface [polypeptide binding]; other site
1211776005150	active site
1211776005151	FMN-binding site [chemical binding]; other site
1211776005152	ribonuclease III; Reviewed; Region: rnc; PRK00102
1211776005153	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1211776005154	dimerization interface [polypeptide binding]; other site
1211776005155	active site
1211776005156	metal binding site [ion binding]; metal-binding site
1211776005157	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1211776005158	dsRNA binding site [nucleotide binding]; other site
1211776005159	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1211776005160	RNA/DNA hybrid binding site [nucleotide binding]; other site
1211776005161	active site
1211776005162	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1211776005163	TPR motif; other site
1211776005164	binding surface
1211776005165	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1211776005166	Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have...; Region: ZZ; cl00295
1211776005167	Zinc-binding sites [ion binding]; other site
1211776005168	zinc cluster 1 [ion binding]; other site
1211776005169	putative charged binding surface; other site
1211776005170	putative hydrophobic binding surface; other site
1211776005171	zinc cluster 2 [ion binding]; other site
1211776005173	DNA primase, catalytic core; Region: dnaG; TIGR01391
1211776005174	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1211776005175	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1211776005176	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1211776005177	active site
1211776005178	metal binding site [ion binding]; metal-binding site
1211776005179	interdomain interaction site; other site
1211776005180	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
1211776005181	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1211776005182	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1211776005183	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1211776005184	hypothetical protein; Provisional; Region: PRK03762
1211776005185	PDZ domain; Region: PDZ_2; pfam13180
1211776005186	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1211776005187	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1211776005188	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1211776005189	substrate binding pocket [chemical binding]; other site
1211776005190	chain length determination region; other site
1211776005191	substrate-Mg2+ binding site; other site
1211776005192	catalytic residues [active]
1211776005193	aspartate-rich region 1; other site
1211776005194	active site lid residues [active]
1211776005195	aspartate-rich region 2; other site
1211776005196	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
1211776005197	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1211776005198	TPP-binding site [chemical binding]; other site
1211776005199	dimer interface [polypeptide binding]; other site
1211776005200	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1211776005201	PYR/PP interface [polypeptide binding]; other site
1211776005202	dimer interface [polypeptide binding]; other site
1211776005203	TPP binding site [chemical binding]; other site
1211776005204	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1211776005205	Sulphate Transporter and Anti-Sigma factor antagonist domain found in the C-terminal region of sulphate transporters as well as in bacterial and archaeal proteins involved in the regulation of sigma factors; Region: STAS; cl00604
1211776005206	ABC-type transport system involved in resistance to organic solvents, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2B; COG0767
1211776005207	Permease; Region: Permease; pfam02405
1211776005209	ABC-type transport system involved in resistance to organic solvents, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2A; COG1127
1211776005210	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1211776005211	Walker A/P-loop; other site
1211776005212	ATP binding site [chemical binding]; other site
1211776005213	Q-loop/lid; other site
1211776005214	ABC transporter signature motif; other site
1211776005215	Walker B; other site
1211776005216	D-loop; other site
1211776005217	H-loop/switch region; other site
1211776005218	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
1211776005219	mce related protein; Region: MCE; pfam02470
1211776005221	ABC-type uncharacterized transport system, auxiliary component [General function prediction only]; Region: COG3218
1211776005222	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1211776005223	active site
1211776005224	Glutamate racemase [Cell envelope biogenesis, outer membrane]; Region: MurI; COG0796
1211776005225	NlpC/P60 family; Region: NLPC_P60; pfam00877
1211776005227	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
1211776005229	Na+/H+ antiporter [Inorganic ion transport and metabolism]; Region: NhaA; COG3004
1211776005231	Putative motility protein; Region: YjfB_motility; pfam14070
1211776005232	High-affinity Fe2+/Pb2+ permease [Inorganic ion transport and metabolism]; Region: FTR1; COG0672
1211776005234	Uncharacterized protein probably involved in high-affinity Fe2+ transport [Inorganic ion transport and metabolism]; Region: Tpd; COG3470
1211776005236	Predicted membrane protein [Function unknown]; Region: COG4393
1211776005237	Predicted membrane protein (DUF2318); Region: DUF2318; pfam10080
1211776005238	Uncharacterized conserved protein [Function unknown]; Region: COG3350
1211776005240	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1211776005241	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1211776005242	FtsX-like permease family; Region: FtsX; pfam02687
1211776005244	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1211776005245	FtsX-like permease family; Region: FtsX; pfam02687
1211776005247	lipoprotein releasing system, ATP-binding protein; Region: LolD_lipo_ex; TIGR02211
1211776005248	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1211776005249	Walker A/P-loop; other site
1211776005250	ATP binding site [chemical binding]; other site
1211776005251	Q-loop/lid; other site
1211776005252	ABC transporter signature motif; other site
1211776005253	Walker B; other site
1211776005254	D-loop; other site
1211776005255	H-loop/switch region; other site
1211776005256	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1211776005257	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1211776005258	catalytic residues [active]
1211776005259	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1211776005260	Predicted metal-binding protein [General function prediction only]; Region: COG3019
1211776005262	DNA ligase; Provisional; Region: PRK09125
1211776005263	Adenylation domain of kDNA ligases and similar proteins; Region: Adenylation_kDNA_ligase_like; cd07896
1211776005264	DNA binding site [nucleotide binding]
1211776005265	active site
1211776005266	The Oligonucleotide/oligosaccharide binding (OB)-fold domain of kDNA ligase-like ATP-dependent DNA ligases is a DNA-binding module that is part of the catalytic core unit; Region: OBF_kDNA_ligase_like; cd08041
1211776005267	DNA binding site [nucleotide binding]
1211776005268	AMIN domain; Region: AMIN; pfam11741
1211776005270	enolase; Provisional; Region: eno; PRK00077
1211776005271	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1211776005272	dimer interface [polypeptide binding]; other site
1211776005273	metal binding site [ion binding]; metal-binding site
1211776005274	substrate binding pocket [chemical binding]; other site
1211776005275	recombinase A; Provisional; Region: recA; PRK09354
1211776005276	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1211776005277	hexamer interface [polypeptide binding]; other site
1211776005278	Walker A motif; other site
1211776005279	ATP binding site [chemical binding]; other site
1211776005280	Walker B motif; other site
1211776005281	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
1211776005282	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1211776005284	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13904
1211776005285	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1211776005286	Autotransporter beta-domain; Region: Autotransporter; smart00869
1211776005287	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1211776005288	binding surface
1211776005289	TPR motif; other site
1211776005290	TPR repeat; Region: TPR_11; pfam13414
1211776005291	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
1211776005292	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
1211776005293	active site
1211776005294	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
1211776005295	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
1211776005296	dimer interface [polypeptide binding]; other site
1211776005297	active site
1211776005298	citrylCoA binding site [chemical binding]; other site
1211776005299	NADH binding [chemical binding]; other site
1211776005300	cationic pore residues; other site
1211776005301	oxalacetate/citrate binding site [chemical binding]; other site
1211776005302	coenzyme A binding site [chemical binding]; other site
1211776005303	catalytic triad [active]
1211776005304	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1211776005305	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1211776005307	biotin synthase; Provisional; Region: PRK08508
1211776005308	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776005309	FeS/SAM binding site; other site
1211776005310	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1211776005311	DNA topoisomerase I; Validated; Region: PRK05582
1211776005312	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1211776005313	active site
1211776005314	interdomain interaction site; other site
1211776005315	putative metal-binding site [ion binding]; other site
1211776005316	nucleotide binding site [chemical binding]; other site
1211776005317	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1211776005318	domain I; other site
1211776005319	DNA binding groove [nucleotide binding]
1211776005320	phosphate binding site [ion binding]; other site
1211776005321	domain II; other site
1211776005322	domain III; other site
1211776005323	nucleotide binding site [chemical binding]; other site
1211776005324	catalytic site [active]
1211776005325	domain IV; other site
1211776005326	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1211776005327	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1211776005328	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1211776005329	putative substrate translocation pore; other site
1211776005330	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1211776005332	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1211776005333	SecY translocase; Region: SecY; pfam00344
1211776005335	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1211776005336	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1211776005337	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1211776005338	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1211776005339	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1211776005340	5S rRNA interface [nucleotide binding]; other site
1211776005341	23S rRNA interface [nucleotide binding]; other site
1211776005342	L5 interface [polypeptide binding]; other site
1211776005343	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1211776005344	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1211776005345	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1211776005346	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1211776005347	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1211776005348	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1211776005349	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1211776005350	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1211776005351	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1211776005352	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1211776005353	RNA binding site [nucleotide binding]; other site
1211776005354	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1211776005355	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1211776005356	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1211776005357	putative translocon interaction site; other site
1211776005358	23S rRNA interface [nucleotide binding]; other site
1211776005359	signal recognition particle (SRP54) interaction site; other site
1211776005360	L23 interface [polypeptide binding]; other site
1211776005361	trigger factor interaction site; other site
1211776005362	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1211776005363	23S rRNA interface [nucleotide binding]; other site
1211776005364	5S rRNA interface [nucleotide binding]; other site
1211776005365	putative antibiotic binding site [chemical binding]; other site
1211776005366	L25 interface [polypeptide binding]; other site
1211776005367	L27 interface [polypeptide binding]; other site
1211776005368	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1211776005369	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1211776005370	G-X-X-G motif; other site
1211776005371	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1211776005372	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1211776005373	putative translocon binding site; other site
1211776005374	protein-rRNA interface [nucleotide binding]; other site
1211776005375	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1211776005376	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1211776005377	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1211776005378	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1211776005379	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1211776005380	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1211776005381	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1211776005382	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1211776005383	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1211776005384	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1211776005385	RNA binding surface [nucleotide binding]; other site
1211776005386	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
1211776005387	active site
1211776005388	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1211776005389	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1211776005390	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1211776005391	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1211776005392	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1211776005393	S-adenosylmethionine binding site [chemical binding]; other site
1211776005394	Phosphorylase superfamily; Region: PNP_UDP_1; cl00303
1211776005395	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14462
1211776005396	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1211776005397	FeS/SAM binding site; other site
1211776005399	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1211776005400	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1211776005401	Coenzyme A binding pocket [chemical binding]; other site
1211776005402	isopropylmalate isomerase small subunit; Provisional; Region: leuD; PRK01641
1211776005403	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1211776005404	substrate binding site [chemical binding]; other site
1211776005405	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1211776005406	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1211776005407	substrate binding site [chemical binding]; other site
1211776005408	ligand binding site [chemical binding]; other site
1211776005409	tartrate dehydrogenase; Region: TTC; TIGR02089
1211776005410	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1211776005411	2-isopropylmalate synthase; Validated; Region: PRK00915
1211776005412	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1211776005413	active site
1211776005414	catalytic residues [active]
1211776005415	metal binding site [ion binding]; metal-binding site
1211776005416	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1211776005417	Outer membrane protein beta-barrel domain; Region: OMP_b-brl; pfam13505
1211776005418	7-cyano-7-deazaguanine reductase; Provisional; Region: PRK13258
1211776005419	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
1211776005420	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1211776005422	homoserine O-succinyltransferase; Region: metA; TIGR01001
1211776005423	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1211776005424	proposed active site lysine [active]
1211776005425	conserved cys residue [active]
1211776005426	OAH/OAS sulfhydrylase; Region: OAH_OAS_sulfhy; TIGR01326
1211776005427	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1211776005428	homodimer interface [polypeptide binding]; other site
1211776005429	substrate-cofactor binding pocket; other site
1211776005430	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1211776005431	catalytic residue [active]
1211776005433	flagellar hook protein FlgE; Validated; Region: flgE; PRK08425
1211776005434	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1211776005435	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1211776005436	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1211776005437	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1211776005438	active site
1211776005439	putative DNA-binding cleft [nucleotide binding]; other site
1211776005440	dimer interface [polypeptide binding]; other site