-- dump date   	20140619_022323
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1029718000001	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1029718000002	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1029718000003	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718000004	Walker A motif; other site
1029718000005	ATP binding site [chemical binding]; other site
1029718000006	Walker B motif; other site
1029718000007	arginine finger; other site
1029718000008	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1029718000009	DnaA box-binding interface [nucleotide binding]; other site
1029718000010	DNA polymerase III subunit beta; Validated; Region: PRK05643
1029718000011	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1029718000012	putative DNA binding surface [nucleotide binding]; other site
1029718000013	dimer interface [polypeptide binding]; other site
1029718000014	beta-clamp/clamp loader binding surface; other site
1029718000015	beta-clamp/translesion DNA polymerase binding surface; other site
1029718000016	recombination protein F; Reviewed; Region: recF; PRK00064
1029718000017	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000018	Walker A/P-loop; other site
1029718000019	ATP binding site [chemical binding]; other site
1029718000020	Q-loop/lid; other site
1029718000021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000022	ABC transporter signature motif; other site
1029718000023	Walker B; other site
1029718000024	D-loop; other site
1029718000025	H-loop/switch region; other site
1029718000026	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1029718000027	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718000028	ATP binding site [chemical binding]; other site
1029718000029	Mg2+ binding site [ion binding]; other site
1029718000030	G-X-G motif; other site
1029718000031	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1029718000032	anchoring element; other site
1029718000033	dimer interface [polypeptide binding]; other site
1029718000034	ATP binding site [chemical binding]; other site
1029718000035	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1029718000036	active site
1029718000037	putative metal-binding site [ion binding]; other site
1029718000038	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1029718000039	DNA gyrase subunit A; Validated; Region: PRK05560
1029718000040	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1029718000041	CAP-like domain; other site
1029718000042	active site
1029718000043	primary dimer interface [polypeptide binding]; other site
1029718000044	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1029718000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1029718000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1029718000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1029718000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1029718000049	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718000050	Zn2+ binding site [ion binding]; other site
1029718000051	Mg2+ binding site [ion binding]; other site
1029718000052	seryl-tRNA synthetase; Provisional; Region: PRK05431
1029718000053	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1029718000054	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1029718000055	dimer interface [polypeptide binding]; other site
1029718000056	active site
1029718000057	motif 1; other site
1029718000058	motif 2; other site
1029718000059	motif 3; other site
1029718000060	tRNA, pseudo
1029718000061	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1029718000062	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1029718000063	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1029718000064	Part of AAA domain; Region: AAA_19; pfam13245
1029718000065	Family description; Region: UvrD_C_2; pfam13538
1029718000066	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1029718000067	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
1029718000068	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1029718000069	active site
1029718000070	NTP binding site [chemical binding]; other site
1029718000071	metal binding triad [ion binding]; metal-binding site
1029718000072	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1029718000073	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1029718000074	generic binding surface II; other site
1029718000075	generic binding surface I; other site
1029718000076	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718000077	Zn2+ binding site [ion binding]; other site
1029718000078	Mg2+ binding site [ion binding]; other site
1029718000079	Predicted transcriptional regulators [Transcription]; Region: COG1695
1029718000080	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1029718000081	Protein of unknown function (DUF1048); Region: DUF1048; pfam06304
1029718000082	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
1029718000083	dimer interface [polypeptide binding]; other site
1029718000084	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1029718000085	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1029718000086	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
1029718000087	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1029718000088	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1029718000089	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718000090	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718000091	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1029718000092	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1029718000093	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718000094	ATP binding site [chemical binding]; other site
1029718000095	putative Mg++ binding site [ion binding]; other site
1029718000096	Domain of unknown function (DUF3387); Region: DUF3387; pfam11867
1029718000097	Chromate transporter; Region: Chromate_transp; pfam02417
1029718000098	Chromate transporter; Region: Chromate_transp; pfam02417
1029718000099	DHHW protein; Region: DHHW; pfam14286
1029718000100	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
1029718000101	Domain of unknown function (DUF4358); Region: DUF4358; pfam14270
1029718000102	prolyl-tRNA synthetase; Provisional; Region: PRK08661
1029718000103	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
1029718000104	dimer interface [polypeptide binding]; other site
1029718000105	motif 1; other site
1029718000106	active site
1029718000107	motif 2; other site
1029718000108	motif 3; other site
1029718000109	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
1029718000110	anticodon binding site; other site
1029718000111	zinc-binding site [ion binding]; other site
1029718000112	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1029718000113	Domain of unknown function DUF21; Region: DUF21; pfam01595
1029718000114	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1029718000115	Transporter associated domain; Region: CorC_HlyC; smart01091
1029718000116	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1029718000117	nucleoside/Zn binding site; other site
1029718000118	dimer interface [polypeptide binding]; other site
1029718000119	catalytic motif [active]
1029718000120	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
1029718000121	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718000122	Walker A motif; other site
1029718000123	ATP binding site [chemical binding]; other site
1029718000124	Walker B motif; other site
1029718000125	hypothetical protein; Validated; Region: PRK00153
1029718000126	recombination protein RecR; Reviewed; Region: recR; PRK00076
1029718000127	RecR protein; Region: RecR; pfam02132
1029718000128	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1029718000129	putative active site [active]
1029718000130	putative metal-binding site [ion binding]; other site
1029718000131	tetramer interface [polypeptide binding]; other site
1029718000132	Protein of unknown function (DUF1576); Region: DUF1576; pfam07613
1029718000133	Protein of unknown function (DUF1576); Region: DUF1576; pfam07613
1029718000134	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1029718000135	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1029718000136	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1029718000137	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1029718000138	putative ATP binding site [chemical binding]; other site
1029718000139	putative substrate interface [chemical binding]; other site
1029718000140	methicillin resistance protein, pseudogene
1029718000141	Predicted methyltransferases [General function prediction only]; Region: COG0313
1029718000142	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1029718000143	putative SAM binding site [chemical binding]; other site
1029718000144	putative homodimer interface [polypeptide binding]; other site
1029718000145	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1029718000146	D-ala-D-ala dipeptidase; Region: Peptidase_M15; cl00813
1029718000147	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1029718000148	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1029718000149	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718000150	This family is most closely related to the GT1 family of glycosyltransferases.  wbaZ in Salmonella enterica has been shown to possess the mannosyl transferase activity. The members of this family are found in certain bacteria and Archaea; Region: GT1_wbaZ_like; cd03804
1029718000151	putative ADP-binding pocket [chemical binding]; other site
1029718000152	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718000153	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1029718000154	Domains similar to the eukaryotic reeler domain and bacterial cohesins; Region: Reeler_cohesin_like; cl14606
1029718000155	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718000156	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1029718000157	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
1029718000158	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718000159	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
1029718000160	putative ADP-binding pocket [chemical binding]; other site
1029718000161	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1029718000162	Bacterial sugar transferase; Region: Bac_transf; pfam02397
1029718000163	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1029718000164	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1029718000165	Substrate binding site; other site
1029718000166	Predicted glycosyltransferases [General function prediction only]; Region: COG1216
1029718000167	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1029718000168	active site
1029718000169	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
1029718000170	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
1029718000171	active site
1029718000172	tetramer interface; other site
1029718000173	Isochorismatase family; Region: Isochorismatase; pfam00857
1029718000174	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1029718000175	catalytic triad [active]
1029718000176	conserved cis-peptide bond; other site
1029718000177	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1029718000178	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1029718000179	dimer interface [polypeptide binding]; other site
1029718000180	ssDNA binding site [nucleotide binding]; other site
1029718000181	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1029718000182	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1029718000183	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1029718000184	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1029718000185	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; cl00500
1029718000186	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1029718000187	alanine racemase; Reviewed; Region: alr; PRK00053
1029718000188	active site
1029718000189	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1029718000190	dimer interface [polypeptide binding]; other site
1029718000191	substrate binding site [chemical binding]; other site
1029718000192	catalytic residues [active]
1029718000193	PemK-like protein; Region: PemK; pfam02452
1029718000194	Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain; Region: NAGLU_N; pfam12971
1029718000195	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain; Region: NAGLU; pfam05089
1029718000196	Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain; Region: NAGLU_C; pfam12972
1029718000197	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1029718000198	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000199	Walker A/P-loop; other site
1029718000200	ATP binding site [chemical binding]; other site
1029718000201	Q-loop/lid; other site
1029718000202	ABC transporter signature motif; other site
1029718000203	Walker B; other site
1029718000204	D-loop; other site
1029718000205	H-loop/switch region; other site
1029718000206	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1029718000207	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1029718000208	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1029718000209	C-terminal peptidase (prc); Region: prc; TIGR00225
1029718000210	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1029718000211	protein binding site [polypeptide binding]; other site
1029718000212	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1029718000213	Catalytic dyad [active]
1029718000214	excinuclease ABC subunit B; Provisional; Region: PRK05298
1029718000215	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718000216	ATP binding site [chemical binding]; other site
1029718000217	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718000218	nucleotide binding region [chemical binding]; other site
1029718000219	ATP-binding site [chemical binding]; other site
1029718000220	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1029718000221	UvrB/uvrC motif; Region: UVR; pfam02151
1029718000222	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1029718000223	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1029718000224	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1029718000225	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1029718000226	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1029718000227	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1029718000228	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1029718000229	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1029718000230	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1029718000231	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1029718000232	GIY-YIG motif/motif A; other site
1029718000233	active site
1029718000234	catalytic site [active]
1029718000235	putative DNA binding site [nucleotide binding]; other site
1029718000236	metal binding site [ion binding]; metal-binding site
1029718000237	UvrB/uvrC motif; Region: UVR; pfam02151
1029718000238	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1029718000239	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1029718000240	FAD binding domain; Region: FAD_binding_4; pfam01565
1029718000241	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1029718000242	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1029718000243	AAA domain; Region: AAA_18; pfam13238
1029718000244	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1029718000245	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1029718000246	putative substrate binding pocket [chemical binding]; other site
1029718000247	dimer interface [polypeptide binding]; other site
1029718000248	phosphate binding site [ion binding]; other site
1029718000249	Sporulation Regulator WhiA C terminal domain; Region: HTH_WhiA; pfam02650
1029718000250	Domain of unknown function (DUF4380); Region: DUF4380; pfam14315
1029718000251	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
1029718000252	active site
1029718000253	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
1029718000254	dimer interface [polypeptide binding]; other site
1029718000255	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
1029718000256	Ligand Binding Site [chemical binding]; other site
1029718000257	Molecular Tunnel; other site
1029718000258	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826
1029718000259	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1029718000260	active site
1029718000261	PHP Thumb interface [polypeptide binding]; other site
1029718000262	metal binding site [ion binding]; metal-binding site
1029718000263	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1029718000264	generic binding surface II; other site
1029718000265	generic binding surface I; other site
1029718000266	6-phosphofructokinase; Provisional; Region: PRK03202
1029718000267	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1029718000268	active site
1029718000269	ADP/pyrophosphate binding site [chemical binding]; other site
1029718000270	dimerization interface [polypeptide binding]; other site
1029718000271	allosteric effector site; other site
1029718000272	fructose-1,6-bisphosphate binding site; other site
1029718000273	Pyruvate kinase [Carbohydrate transport and metabolism]; Region: PykF; COG0469
1029718000274	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1029718000275	domain interfaces; other site
1029718000276	active site
1029718000277	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
1029718000278	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1029718000279	prophage SFBMP1
1029718000280	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1029718000281	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1029718000282	active site
1029718000283	DNA binding site [nucleotide binding]
1029718000284	Int/Topo IB signature motif; other site
1029718000285	Predicted ATPases [General function prediction only]; Region: COG1106
1029718000286	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000287	Walker A/P-loop; other site
1029718000288	ATP binding site [chemical binding]; other site
1029718000289	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000290	ABC transporter signature motif; other site
1029718000291	Walker B; other site
1029718000292	D-loop; other site
1029718000293	H-loop/switch region; other site
1029718000294	LexA repressor, partial, pseudogene
1029718000295	Protein of unknown function (DUF3644); Region: DUF3644; pfam12358
1029718000296	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000297	non-specific DNA binding site [nucleotide binding]; other site
1029718000298	salt bridge; other site
1029718000299	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
1029718000300	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000301	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1029718000302	Catalytic site [active]
1029718000303	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1029718000304	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000305	non-specific DNA binding site [nucleotide binding]; other site
1029718000306	salt bridge; other site
1029718000307	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000308	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000309	non-specific DNA binding site [nucleotide binding]; other site
1029718000310	salt bridge; other site
1029718000311	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000312	Prophage antirepressor [Transcription]; Region: COG3617
1029718000313	BRO family, N-terminal domain; Region: Bro-N; pfam02498
1029718000314	Phage antirepressor protein KilAC domain; Region: ANT; cl01462
1029718000315	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1029718000316	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000317	non-specific DNA binding site [nucleotide binding]; other site
1029718000318	salt bridge; other site
1029718000319	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000320	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1029718000321	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000322	non-specific DNA binding site [nucleotide binding]; other site
1029718000323	salt bridge; other site
1029718000324	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000325	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
1029718000326	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
1029718000327	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_A; cd08642
1029718000328	active site
1029718000329	DNA binding site [nucleotide binding]
1029718000330	catalytic site [active]
1029718000331	virulence-associated E family protein, pseudogene
1029718000332	VRR-NUC domain; Region: VRR_NUC; pfam08774
1029718000333	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1029718000334	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718000335	ATP binding site [chemical binding]; other site
1029718000336	putative Mg++ binding site [ion binding]; other site
1029718000337	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718000338	nucleotide binding region [chemical binding]; other site
1029718000339	ATP-binding site [chemical binding]; other site
1029718000340	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000341	salt bridge; other site
1029718000342	non-specific DNA binding site [nucleotide binding]; other site
1029718000343	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000344	Short C-terminal domain; Region: SHOCT; pfam09851
1029718000345	Terminase small subunit; Region: Terminase_2; pfam03592
1029718000346	Phage terminase large subunit; Region: Terminase_3; cl12054
1029718000347	Terminase-like family; Region: Terminase_6; pfam03237
1029718000348	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1029718000349	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1029718000350	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000351	salt bridge; other site
1029718000352	non-specific DNA binding site [nucleotide binding]; other site
1029718000353	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000354	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1029718000355	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
1029718000356	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
1029718000357	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1029718000358	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1029718000359	active site
1029718000360	conformational flexibility of ligand binding pocket; other site
1029718000361	ADP-ribosylating toxin turn-turn motif; other site
1029718000362	YjcQ protein; Region: YjcQ; pfam09639
1029718000363	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
1029718000364	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
1029718000365	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
1029718000366	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
1029718000367	Phage XkdN-like protein; Region: XkdN; pfam08890
1029718000368	Phage-related minor tail protein [Function unknown]; Region: COG5281
1029718000369	tape measure domain; Region: tape_meas_nterm; TIGR02675
1029718000370	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
1029718000371	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
1029718000372	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
1029718000373	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
1029718000374	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1029718000375	aconitate hydratase; Validated; Region: PRK09277
1029718000376	Holin family; Region: Phage_holin_4; pfam05105
1029718000377	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1029718000378	amidase catalytic site [active]
1029718000379	Zn binding residues [ion binding]; other site
1029718000380	substrate binding site [chemical binding]; other site
1029718000381	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718000382	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1029718000383	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718000384	salt bridge; other site
1029718000385	non-specific DNA binding site [nucleotide binding]; other site
1029718000386	sequence-specific DNA binding site [nucleotide binding]; other site
1029718000387	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1029718000388	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718000389	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1029718000390	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1029718000391	Catalytic site [active]
1029718000392	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1029718000393	Part of AAA domain; Region: AAA_19; pfam13245
1029718000394	Family description; Region: UvrD_C_2; pfam13538
1029718000395	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1029718000396	Cation efflux family; Region: Cation_efflux; cl00316
1029718000397	aspartate kinase; Reviewed; Region: PRK06635
1029718000398	AAK_AK-DapG-like: Amino Acid Kinase Superfamily (AAK), AK-DapG-like; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional enzymes found in Bacilli; Region: AAK_AK-DapG-like; cd04246
1029718000399	putative catalytic residues [active]
1029718000400	putative nucleotide binding site [chemical binding]; other site
1029718000401	putative aspartate binding site [chemical binding]; other site
1029718000402	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891
1029718000403	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
1029718000404	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1029718000405	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1029718000406	active site
1029718000407	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1029718000408	substrate binding site [chemical binding]; other site
1029718000409	catalytic residues [active]
1029718000410	dimer interface [polypeptide binding]; other site
1029718000411	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
1029718000412	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
1029718000413	active site
1029718000414	metal binding site [ion binding]; metal-binding site
1029718000415	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1029718000416	homotrimer interaction site [polypeptide binding]; other site
1029718000417	zinc binding site [ion binding]; other site
1029718000418	CDP-binding sites; other site
1029718000419	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1029718000420	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718000421	RNA binding surface [nucleotide binding]; other site
1029718000422	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
1029718000423	probable active site [active]
1029718000424	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1029718000425	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1029718000426	arsenate reductase, partial, pseudogene
1029718000427	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1029718000428	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1029718000429	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1029718000430	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1029718000431	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1029718000432	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1029718000433	HlyD family secretion protein; Region: HlyD_3; pfam13437
1029718000434	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1029718000435	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1029718000436	Walker A/P-loop; other site
1029718000437	ATP binding site [chemical binding]; other site
1029718000438	Q-loop/lid; other site
1029718000439	ABC transporter signature motif; other site
1029718000440	Walker B; other site
1029718000441	D-loop; other site
1029718000442	H-loop/switch region; other site
1029718000443	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1029718000444	FtsX-like permease family; Region: FtsX; pfam02687
1029718000445	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
1029718000446	phosphonoacetate hydrolase; Region: hydr_PhnA; TIGR02335
1029718000447	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
1029718000448	active site
1029718000449	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1029718000450	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1029718000451	Walker A/P-loop; other site
1029718000452	ATP binding site [chemical binding]; other site
1029718000453	Q-loop/lid; other site
1029718000454	ABC transporter signature motif; other site
1029718000455	Walker B; other site
1029718000456	D-loop; other site
1029718000457	H-loop/switch region; other site
1029718000458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718000459	dimer interface [polypeptide binding]; other site
1029718000460	conserved gate region; other site
1029718000461	putative PBP binding loops; other site
1029718000462	ABC-ATPase subunit interface; other site
1029718000463	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1029718000464	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1029718000465	substrate binding pocket [chemical binding]; other site
1029718000466	membrane-bound complex binding site; other site
1029718000467	hinge residues; other site
1029718000468	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
1029718000469	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1029718000470	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1029718000471	putative active site [active]
1029718000472	catalytic site [active]
1029718000473	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1029718000474	putative active site [active]
1029718000475	catalytic site [active]
1029718000476	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1029718000477	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
1029718000478	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1029718000479	Concanavalin A-like lectin/glucanases superfamily; Region: Laminin_G_3; pfam13385
1029718000480	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
1029718000481	Beta galactosidase small chain; Region: Bgal_small_N; cl03787
1029718000482	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1029718000483	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1029718000484	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4603
1029718000485	Transmembrane subunit (TM) of Treponema pallidum (Tp) RbsC-1, RbsC-2 and related proteins. This is a functionally uncharacterized subgroup of TMs which belong to a larger group of TMs of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette; Region: TM_PBP1_transp_TpRbsC_like; cd06580
1029718000486	TM-ABC transporter signature motif; other site
1029718000487	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
1029718000488	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1029718000489	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1029718000490	Phosphoglycerate kinase; Region: PGK; pfam00162
1029718000491	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1029718000492	substrate binding site [chemical binding]; other site
1029718000493	hinge regions; other site
1029718000494	ADP binding site [chemical binding]; other site
1029718000495	catalytic site [active]
1029718000496	triosephosphate isomerase; Provisional; Region: PRK14567
1029718000497	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1029718000498	substrate binding site [chemical binding]; other site
1029718000499	dimer interface [polypeptide binding]; other site
1029718000500	catalytic triad [active]
1029718000501	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1029718000502	phosphoglyceromutase; Provisional; Region: PRK05434
1029718000503	enolase; Provisional; Region: eno; PRK00077
1029718000504	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1029718000505	dimer interface [polypeptide binding]; other site
1029718000506	metal binding site [ion binding]; metal-binding site
1029718000507	substrate binding pocket [chemical binding]; other site
1029718000508	shikimate 5-dehydrogenase; Reviewed; Region: aroE; PRK00258
1029718000509	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1029718000510	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1029718000511	shikimate binding site; other site
1029718000512	NAD(P) binding site [chemical binding]; other site
1029718000513	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1029718000514	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1029718000515	trimer interface [polypeptide binding]; other site
1029718000516	active site
1029718000517	dimer interface [polypeptide binding]; other site
1029718000518	Chorismate mutase type II; Region: CM_2; cl00693
1029718000519	shikimate kinase; Reviewed; Region: aroK; PRK00131
1029718000520	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1029718000521	ADP binding site [chemical binding]; other site
1029718000522	magnesium binding site [ion binding]; other site
1029718000523	putative shikimate binding site; other site
1029718000524	Preprotein translocase SecG subunit; Region: SecG; pfam03840
1029718000525	ribonuclease R; Region: RNase_R; TIGR02063
1029718000526	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1029718000527	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1029718000528	RNB domain; Region: RNB; pfam00773
1029718000529	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1029718000530	RNA binding site [nucleotide binding]; other site
1029718000531	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1029718000532	SmpB-tmRNA interface; other site
1029718000533	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cl00065
1029718000534	inner membrane transporter YjeM; Provisional; Region: PRK15238
1029718000535	RibD C-terminal domain; Region: RibD_C; cl17279
1029718000536	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1029718000537	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1029718000538	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
1029718000539	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
1029718000540	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
1029718000541	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
1029718000542	active site
1029718000543	P-loop; other site
1029718000544	phosphorylation site [posttranslational modification]
1029718000545	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1029718000546	active site
1029718000547	phosphorylation site [posttranslational modification]
1029718000548	PRD domain; Region: PRD; pfam00874
1029718000549	PRD domain; Region: PRD; pfam00874
1029718000550	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1029718000551	active site
1029718000552	P-loop; other site
1029718000553	phosphorylation site [posttranslational modification]
1029718000554	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
1029718000555	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
1029718000556	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
1029718000557	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1029718000558	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1029718000559	active site
1029718000560	metal binding site [ion binding]; metal-binding site
1029718000561	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1029718000562	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1029718000563	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1029718000564	dimerization interface [polypeptide binding]; other site
1029718000565	putative DNA binding site [nucleotide binding]; other site
1029718000566	putative Zn2+ binding site [ion binding]; other site
1029718000567	NAD synthetase; Reviewed; Region: nadE; PRK02628
1029718000568	Glutamine aminotransferase (GAT, glutaminase) domain of glutamine-dependent NAD synthetases (class 7 and 8 nitrilases); Region: GAT_Gln-NAD-synth; cd07570
1029718000569	multimer interface [polypeptide binding]; other site
1029718000570	active site
1029718000571	catalytic triad [active]
1029718000572	protein interface 1 [polypeptide binding]; other site
1029718000573	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1029718000574	homodimer interface [polypeptide binding]; other site
1029718000575	NAD binding pocket [chemical binding]; other site
1029718000576	ATP binding pocket [chemical binding]; other site
1029718000577	Mg binding site [ion binding]; other site
1029718000578	active-site loop [active]
1029718000579	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1029718000580	ligand binding site [chemical binding]; other site
1029718000581	active site
1029718000582	UGI interface [polypeptide binding]; other site
1029718000583	catalytic site [active]
1029718000584	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1029718000585	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1029718000586	catalytic residue [active]
1029718000587	Domain of unknown function (DUF4407); Region: DUF4407; pfam14362
1029718000588	diaminopimelate epimerase; Provisional; Region: PRK13577
1029718000589	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1029718000590	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
1029718000591	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1029718000592	classical (c) SDRs; Region: SDR_c; cd05233
1029718000593	NAD(P) binding site [chemical binding]; other site
1029718000594	active site
1029718000595	TraX protein; Region: TraX; cl05434
1029718000596	AAA domain; Region: AAA_21; pfam13304
1029718000597	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1029718000598	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
1029718000599	NAD(P) binding site [chemical binding]; other site
1029718000600	catalytic residues [active]
1029718000601	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1029718000602	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1029718000603	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1029718000604	active site
1029718000605	trimer interface [polypeptide binding]; other site
1029718000606	allosteric site; other site
1029718000607	active site lid [active]
1029718000608	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1029718000609	Beta propeller domain; Region: Beta_propel; pfam09826
1029718000610	spermidine synthase; Provisional; Region: PRK00811
1029718000611	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718000612	S-adenosylmethionine binding site [chemical binding]; other site
1029718000613	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
1029718000614	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
1029718000615	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1029718000616	Ligand Binding Site [chemical binding]; other site
1029718000617	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1029718000618	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1029718000619	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1029718000620	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1029718000621	active site
1029718000622	HIGH motif; other site
1029718000623	nucleotide binding site [chemical binding]; other site
1029718000624	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1029718000625	KMSKS motif; other site
1029718000626	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1029718000627	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1029718000628	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1029718000629	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1029718000630	active site
1029718000631	metal binding site [ion binding]; metal-binding site
1029718000632	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1029718000633	Catalytic site [active]
1029718000634	Domain of unknown function (DUF4250); Region: DUF4250; pfam14056
1029718000635	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1029718000636	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1029718000637	metal-binding site [ion binding]
1029718000638	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1029718000639	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1029718000640	Staphylococcal nuclease homologues; Region: SNc; smart00318
1029718000641	Staphylococcal nuclease homologues. SNase homologues are found in bacteria, archaea, and eukaryotes. They contain no disufide bonds; Region: SNc; cl00140
1029718000642	Catalytic site; other site
1029718000643	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1029718000644	metal-binding site [ion binding]
1029718000645	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1029718000646	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1029718000647	active site
1029718000648	HIGH motif; other site
1029718000649	nucleotide binding site [chemical binding]; other site
1029718000650	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1029718000651	active site
1029718000652	KMSKS motif; other site
1029718000653	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1029718000654	tRNA binding surface [nucleotide binding]; other site
1029718000655	anticodon binding site; other site
1029718000656	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1029718000657	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1029718000658	DNA binding site [nucleotide binding]
1029718000659	domain linker motif; other site
1029718000660	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1029718000661	dimerization interface [polypeptide binding]; other site
1029718000662	ligand binding site [chemical binding]; other site
1029718000663	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1029718000664	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1029718000665	phosphodiesterase; Provisional; Region: PRK12704
1029718000666	proline aminopeptidase P II; Provisional; Region: PRK10879
1029718000667	Aminopeptidase P, N-terminal domain; Region: AMP_N; smart01011
1029718000668	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
1029718000669	active site
1029718000670	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
1029718000671	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
1029718000672	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1029718000673	RNA binding site [nucleotide binding]; other site
1029718000674	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1029718000675	RNA binding site [nucleotide binding]; other site
1029718000676	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1029718000677	RNA binding site [nucleotide binding]; other site
1029718000678	Ribosomal protein S1-like RNA-binding domain; Region: S1; smart00316
1029718000679	RNA binding site [nucleotide binding]; other site
1029718000680	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1029718000681	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1029718000682	metal binding site [ion binding]; metal-binding site
1029718000683	dimer interface [polypeptide binding]; other site
1029718000684	Rhomboid family; Region: Rhomboid; cl11446
1029718000685	TspO/MBR family; Region: TspO_MBR; pfam03073
1029718000686	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1029718000687	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
1029718000688	active site
1029718000689	Fucose 4-O-acetylase and related acetyltransferases [Carbohydrate transport and metabolism]; Region: NolL; COG3594
1029718000690	RmuC family; Region: RmuC; pfam02646
1029718000691	DNA polymerase I; Provisional; Region: PRK05755
1029718000692	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1029718000693	active site
1029718000694	metal binding site 1 [ion binding]; metal-binding site
1029718000695	putative 5' ssDNA interaction site; other site
1029718000696	metal binding site 3; metal-binding site
1029718000697	metal binding site 2 [ion binding]; metal-binding site
1029718000698	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1029718000699	putative DNA binding site [nucleotide binding]; other site
1029718000700	putative metal binding site [ion binding]; other site
1029718000701	DnaQ-like (or DEDD) 3'-5' exonuclease domain superfamily; Region: DnaQ_like_exo; cl10012
1029718000702	active site
1029718000703	substrate binding site [chemical binding]; other site
1029718000704	catalytic site [active]
1029718000705	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1029718000706	active site
1029718000707	DNA binding site [nucleotide binding]
1029718000708	catalytic site [active]
1029718000709	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1029718000710	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1029718000711	CoA-binding site [chemical binding]; other site
1029718000712	ATP-binding [chemical binding]; other site
1029718000713	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1029718000714	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1029718000715	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1029718000716	catalytic residue [active]
1029718000717	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
1029718000718	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl15429
1029718000719	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1029718000720	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1029718000721	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1029718000722	NodB motif; other site
1029718000723	active site
1029718000724	catalytic site [active]
1029718000725	Zn binding site [ion binding]; other site
1029718000726	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718000727	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718000728	active site
1029718000729	phosphorylation site [posttranslational modification]
1029718000730	intermolecular recognition site; other site
1029718000731	dimerization interface [polypeptide binding]; other site
1029718000732	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718000733	DNA binding site [nucleotide binding]
1029718000734	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718000735	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1029718000736	dimerization interface [polypeptide binding]; other site
1029718000737	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718000738	dimer interface [polypeptide binding]; other site
1029718000739	phosphorylation site [posttranslational modification]
1029718000740	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718000741	ATP binding site [chemical binding]; other site
1029718000742	Mg2+ binding site [ion binding]; other site
1029718000743	G-X-G motif; other site
1029718000744	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cl00436
1029718000745	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
1029718000746	CPxP  motif; other site
1029718000747	DsrE/DsrF-like family; Region: DrsE; pfam02635
1029718000748	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
1029718000749	UGMP family protein; Validated; Region: PRK09604
1029718000750	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
1029718000751	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
1029718000752	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1029718000753	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1029718000754	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1029718000755	protein binding site [polypeptide binding]; other site
1029718000756	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1029718000757	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000758	Walker A/P-loop; other site
1029718000759	ATP binding site [chemical binding]; other site
1029718000760	Q-loop/lid; other site
1029718000761	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1029718000762	ABC transporter; Region: ABC_tran_2; pfam12848
1029718000763	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1029718000764	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
1029718000765	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
1029718000766	putative active site cavity [active]
1029718000767	N-acetylneuraminate lyase; Provisional; Region: PRK04147
1029718000768	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
1029718000769	inhibitor site; inhibition site
1029718000770	active site
1029718000771	dimer interface [polypeptide binding]; other site
1029718000772	catalytic residue [active]
1029718000773	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
1029718000774	Na binding site [ion binding]; other site
1029718000775	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1029718000776	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1029718000777	nucleotide binding site [chemical binding]; other site
1029718000778	Predicted membrane protein [Function unknown]; Region: COG1971
1029718000779	ferric uptake regulator; Provisional; Region: fur; PRK09462
1029718000780	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1029718000781	metal binding site 2 [ion binding]; metal-binding site
1029718000782	putative DNA binding helix; other site
1029718000783	metal binding site 1 [ion binding]; metal-binding site
1029718000784	dimer interface [polypeptide binding]; other site
1029718000785	structural Zn2+ binding site [ion binding]; other site
1029718000786	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1029718000787	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718000788	Walker A/P-loop; other site
1029718000789	ATP binding site [chemical binding]; other site
1029718000790	Q-loop/lid; other site
1029718000791	ABC transporter signature motif; other site
1029718000792	Walker B; other site
1029718000793	D-loop; other site
1029718000794	H-loop/switch region; other site
1029718000795	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1029718000796	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1029718000797	intersubunit interface [polypeptide binding]; other site
1029718000798	Rhomboid family; Region: Rhomboid; cl11446
1029718000799	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
1029718000800	YtxH-like protein; Region: YtxH; cl02079
1029718000801	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1029718000802	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1029718000803	Peptidase family M23; Region: Peptidase_M23; pfam01551
1029718000804	trigger factor; Provisional; Region: tig; PRK01490
1029718000805	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1029718000806	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1029718000807	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1029718000808	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1029718000809	oligomer interface [polypeptide binding]; other site
1029718000810	active site residues [active]
1029718000811	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1029718000812	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1029718000813	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718000814	Walker A motif; other site
1029718000815	ATP binding site [chemical binding]; other site
1029718000816	Walker B motif; other site
1029718000817	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1029718000818	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1029718000819	G1 box; other site
1029718000820	GTP/Mg2+ binding site [chemical binding]; other site
1029718000821	Switch I region; other site
1029718000822	G2 box; other site
1029718000823	G3 box; other site
1029718000824	Switch II region; other site
1029718000825	G4 box; other site
1029718000826	G5 box; other site
1029718000827	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cl02542
1029718000828	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1029718000829	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1029718000830	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1029718000831	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
1029718000832	metal binding site [ion binding]; metal-binding site
1029718000833	dimer interface [polypeptide binding]; other site
1029718000834	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1029718000835	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718000836	RNA binding surface [nucleotide binding]; other site
1029718000837	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1029718000838	active site
1029718000839	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1029718000840	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1029718000841	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
1029718000842	Zn binding site [ion binding]; other site
1029718000843	V-type ATP synthase subunit I; Validated; Region: PRK05771
1029718000844	V-type ATP synthase subunit K; Validated; Region: PRK06558
1029718000845	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
1029718000846	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
1029718000847	V-type ATP synthase subunit E; Provisional; Region: PRK03963; cl17074
1029718000848	V-type ATP synthase subunit E; Provisional; Region: PRK02292
1029718000849	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
1029718000850	V-type ATP synthase subunit C; Provisional; Region: PRK01198; cl00660
1029718000851	ATP synthase (F/14-kDa) subunit; Region: ATP-synt_F; cl00632
1029718000852	V-type ATP synthase subunit A; Provisional; Region: PRK04192
1029718000853	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1029718000854	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
1029718000855	Walker A motif/ATP binding site; other site
1029718000856	Walker B motif; other site
1029718000857	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1029718000858	V-type ATP synthase subunit B; Provisional; Region: PRK04196
1029718000859	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1029718000860	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
1029718000861	Walker A motif homologous position; other site
1029718000862	Walker B motif; other site
1029718000863	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1029718000864	V-type ATP synthase subunit D; Reviewed; Region: PRK00373
1029718000865	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1029718000866	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1029718000867	Catalytic site [active]
1029718000868	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
1029718000869	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
1029718000870	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1029718000871	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1029718000872	substrate binding site [chemical binding]; other site
1029718000873	hexamer interface [polypeptide binding]; other site
1029718000874	metal binding site [ion binding]; metal-binding site
1029718000875	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1029718000876	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1029718000877	CoA binding domain; Region: CoA_binding; pfam02629
1029718000878	3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase [DNA replication, recombination, and repair]; Region: AlkA; COG0122
1029718000879	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
1029718000880	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1029718000881	minor groove reading motif; other site
1029718000882	helix-hairpin-helix signature motif; other site
1029718000883	substrate binding pocket [chemical binding]; other site
1029718000884	active site
1029718000885	Pleckstrin homology (PH)-like domains in bacteria (PHb); Region: PH-like_bacteria; cd13225
1029718000886	pentamer interface [polypeptide binding]; other site
1029718000887	dodecaamer interface [polypeptide binding]; other site
1029718000888	Protein of unknown function (DUF1292); Region: DUF1292; cl01608
1029718000889	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1029718000890	SdpI/YhfL protein family; Region: SdpI; pfam13630
1029718000891	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1029718000892	dimerization interface [polypeptide binding]; other site
1029718000893	putative DNA binding site [nucleotide binding]; other site
1029718000894	putative Zn2+ binding site [ion binding]; other site
1029718000895	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1029718000896	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
1029718000897	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1029718000898	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1029718000899	Hpr binding site; other site
1029718000900	active site
1029718000901	homohexamer subunit interaction site [polypeptide binding]; other site
1029718000902	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
1029718000903	Thermotoga maritima CorA-like family; Region: TmCorA-like; cd12822
1029718000904	oligomer interface [polypeptide binding]; other site
1029718000905	metal binding site [ion binding]; metal-binding site
1029718000906	metal binding site [ion binding]; metal-binding site
1029718000907	putative Cl binding site [ion binding]; other site
1029718000908	aspartate ring; other site
1029718000909	basic sphincter; other site
1029718000910	hydrophobic gate; other site
1029718000911	periplasmic entrance; other site
1029718000912	M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659
1029718000913	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
1029718000914	oligomer interface [polypeptide binding]; other site
1029718000915	putative active site [active]
1029718000916	metal binding site [ion binding]; metal-binding site
1029718000917	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718000918	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1029718000919	active site
1029718000920	motif I; other site
1029718000921	motif II; other site
1029718000922	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718000923	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
1029718000924	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
1029718000925	active pocket/dimerization site; other site
1029718000926	active site
1029718000927	phosphorylation site [posttranslational modification]
1029718000928	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
1029718000929	active site
1029718000930	phosphorylation site [posttranslational modification]
1029718000931	PTS system sorbose-specific iic component; Region: EII-Sor; cl01506
1029718000932	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID [Carbohydrate transport and metabolism]; Region: ManZ; COG3716
1029718000933	Domain of unknown function (DUF956); Region: DUF956; pfam06115
1029718000934	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1029718000935	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1029718000936	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
1029718000937	myosin-cross-reactive antigen; Provisional; Region: PRK13977
1029718000938	UDP-glucose 4-epimerase; Region: PLN02240
1029718000939	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
1029718000940	NAD binding site [chemical binding]; other site
1029718000941	homodimer interface [polypeptide binding]; other site
1029718000942	active site
1029718000943	substrate binding site [chemical binding]; other site
1029718000944	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1029718000945	NfeD-like C-terminal, partner-binding; Region: NfeD; cl00686
1029718000946	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1029718000947	HflK protein; Region: hflK; TIGR01933
1029718000948	Domain of unknown function (DUF368); Region: DUF368; pfam04018
1029718000949	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1029718000950	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1029718000951	CYTH-like (also known as triphosphate tunnel metalloenzyme (TTM)-like) Phosphatases; Region: CYTH-like_Pase; cl11964
1029718000952	putative active site; other site
1029718000953	putative triphosphate binding site [ion binding]; other site
1029718000954	signature motif; other site
1029718000955	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1029718000956	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1029718000957	intersubunit interface [polypeptide binding]; other site
1029718000958	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1029718000959	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718000960	ABC-ATPase subunit  interface; other site
1029718000961	dimer interface [polypeptide binding]; other site
1029718000962	putative PBP binding regions; other site
1029718000963	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1029718000964	Walker A/P-loop; other site
1029718000965	ATP binding site [chemical binding]; other site
1029718000966	ABC transporter; Region: ABC_tran; pfam00005
1029718000967	Q-loop/lid; other site
1029718000968	ABC transporter signature motif; other site
1029718000969	Walker B; other site
1029718000970	D-loop; other site
1029718000971	H-loop/switch region; other site
1029718000972	Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). This family consists of various deoxynucleoside kinases including deoxyribo- cytidine (EC 2.7.1.74), guanosine (EC 2.7.1; Region: dNK; cd01673
1029718000973	Substrate-binding site [chemical binding]; other site
1029718000974	Substrate specificity [chemical binding]; other site
1029718000975	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
1029718000976	AAA domain; Region: AAA_17; pfam13207
1029718000977	conserved hypothetical protein (putative transposase or invertase); Region: T_den_put_tspse; TIGR01784
1029718000978	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718000979	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718000980	active site
1029718000981	phosphorylation site [posttranslational modification]
1029718000982	intermolecular recognition site; other site
1029718000983	dimerization interface [polypeptide binding]; other site
1029718000984	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718000985	DNA binding site [nucleotide binding]
1029718000986	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718000987	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718000988	dimer interface [polypeptide binding]; other site
1029718000989	phosphorylation site [posttranslational modification]
1029718000990	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718000991	ATP binding site [chemical binding]; other site
1029718000992	Mg2+ binding site [ion binding]; other site
1029718000993	G-X-G motif; other site
1029718000994	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
1029718000995	putative metal binding residues [ion binding]; other site
1029718000996	signature motif; other site
1029718000997	dimer interface [polypeptide binding]; other site
1029718000998	active site
1029718000999	polyP binding site; other site
1029718001000	substrate binding site [chemical binding]; other site
1029718001001	acceptor-phosphate pocket; other site
1029718001002	Domain of unknown function (DUF4353); Region: DUF4353; pfam14262
1029718001003	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1029718001004	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; smart00831
1029718001005	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1029718001006	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1029718001007	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1029718001008	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1029718001009	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1029718001010	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1029718001011	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1029718001012	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1029718001013	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718001014	non-specific DNA binding site [nucleotide binding]; other site
1029718001015	salt bridge; other site
1029718001016	sequence-specific DNA binding site [nucleotide binding]; other site
1029718001017	prophage SFBMP2, partial
1029718001018	Terminase small subunit; Region: Terminase_2; pfam03592
1029718001019	Domain of unknown function (DUF4160); Region: DUF4160; pfam13711
1029718001020	Protein of unknown function (DUF2442); Region: DUF2442; pfam10387
1029718001021	Phage terminase large subunit; Region: Terminase_3; cl12054
1029718001022	Terminase-like family; Region: Terminase_6; pfam03237
1029718001023	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
1029718001024	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1029718001025	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1029718001026	active site
1029718001027	conformational flexibility of ligand binding pocket; other site
1029718001028	ADP-ribosylating toxin turn-turn motif; other site
1029718001029	YjcQ protein; Region: YjcQ; pfam09639
1029718001030	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
1029718001031	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; cl09775
1029718001032	AAA domain; Region: AAA_21; pfam13304
1029718001033	RloB-like protein; Region: RloB; pfam13707
1029718001034	Predicted membrane protein [Function unknown]; Region: COG2364
1029718001035	Rubrerythrin [Energy production and conversion]; Region: COG1592
1029718001036	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1029718001037	binuclear metal center [ion binding]; other site
1029718001038	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1029718001039	iron binding site [ion binding]; other site
1029718001040	AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like1; cd06061
1029718001041	thiamine-monophosphate kinase; Region: thiL; TIGR01379
1029718001042	dimerization interface [polypeptide binding]; other site
1029718001043	putative ATP binding site [chemical binding]; other site
1029718001044	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1029718001045	active site
1029718001046	dimerization interface [polypeptide binding]; other site
1029718001047	Predicted 6-phosphogluconate dehydrogenase [Carbohydrate transport and metabolism]; Region: Gnd; COG1023
1029718001048	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
1029718001049	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
1029718001050	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
1029718001051	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
1029718001052	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1029718001053	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1029718001054	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1029718001055	Walker A/P-loop; other site
1029718001056	ATP binding site [chemical binding]; other site
1029718001057	Q-loop/lid; other site
1029718001058	ABC transporter signature motif; other site
1029718001059	Walker B; other site
1029718001060	D-loop; other site
1029718001061	H-loop/switch region; other site
1029718001062	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1029718001063	FtsX-like permease family; Region: FtsX; pfam02687
1029718001064	Stage II sporulation protein; Region: SpoIID; pfam08486
1029718001065	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1029718001066	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1029718001067	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1029718001068	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1029718001069	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1029718001070	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1029718001071	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1029718001072	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1029718001073	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1029718001074	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1029718001075	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
1029718001076	active site
1029718001077	dimer interface [polypeptide binding]; other site
1029718001078	catalytic nucleophile [active]
1029718001079	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1029718001080	Predicted membrane protein [Function unknown]; Region: COG4684
1029718001081	Fumble; Region: Fumble; cl17357
1029718001082	pantothenate kinase, eukaryotic/staphyloccocal type; Region: panK_eukar; TIGR00555
1029718001083	Protein of unknown function (DUF328); Region: DUF328; pfam03883
1029718001084	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1029718001085	NlpC/P60 family; Region: NLPC_P60; pfam00877
1029718001086	rod shape-determining protein MreB; Provisional; Region: PRK13927
1029718001087	MreB and similar proteins; Region: MreB_like; cd10225
1029718001088	nucleotide binding site [chemical binding]; other site
1029718001089	Mg binding site [ion binding]; other site
1029718001090	putative protofilament interaction site [polypeptide binding]; other site
1029718001091	RodZ interaction site [polypeptide binding]; other site
1029718001092	rod shape-determining protein MreC; Provisional; Region: PRK13922
1029718001093	basic region leucin zipper; Region: BRLZ; smart00338
1029718001094	rod shape-determining protein MreC; Region: MreC; pfam04085
1029718001095	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1029718001096	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1029718001097	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1029718001098	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1029718001099	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1029718001100	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1029718001101	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1029718001102	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1029718001103	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1029718001104	Switch I; other site
1029718001105	Switch II; other site
1029718001106	Septum formation topological specificity factor MinE; Region: MinE; cl00538
1029718001107	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1029718001108	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1029718001109	active site
1029718001110	putative substrate binding region [chemical binding]; other site
1029718001111	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1029718001112	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1029718001113	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1029718001114	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1029718001115	GTP1/OBG; Region: GTP1_OBG; pfam01018
1029718001116	Obg GTPase; Region: Obg; cd01898
1029718001117	G1 box; other site
1029718001118	GTP/Mg2+ binding site [chemical binding]; other site
1029718001119	Switch I region; other site
1029718001120	G2 box; other site
1029718001121	G3 box; other site
1029718001122	Switch II region; other site
1029718001123	G4 box; other site
1029718001124	G5 box; other site
1029718001125	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1029718001126	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1029718001127	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1029718001128	active site
1029718001129	(T/H)XGH motif; other site
1029718001130	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718001131	Zn2+ binding site [ion binding]; other site
1029718001132	Mg2+ binding site [ion binding]; other site
1029718001133	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1029718001134	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1029718001135	active site
1029718001136	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1029718001137	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1029718001138	SLBB domain; Region: SLBB; pfam10531
1029718001139	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
1029718001140	Helix-hairpin-helix motif; Region: HHH; pfam00633
1029718001141	selenophosphate synthetase; Provisional; Region: PRK00943
1029718001142	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1029718001143	dimerization interface [polypeptide binding]; other site
1029718001144	putative ATP binding site [chemical binding]; other site
1029718001145	selenocysteine synthase; Provisional; Region: PRK04311
1029718001146	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
1029718001147	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1029718001148	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1029718001149	catalytic residue [active]
1029718001150	selenocysteine-specific elongation factor SelB; Region: selB; TIGR00475
1029718001151	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1029718001152	G1 box; other site
1029718001153	putative GEF interaction site [polypeptide binding]; other site
1029718001154	GTP/Mg2+ binding site [chemical binding]; other site
1029718001155	Switch I region; other site
1029718001156	G2 box; other site
1029718001157	G3 box; other site
1029718001158	Switch II region; other site
1029718001159	G4 box; other site
1029718001160	G5 box; other site
1029718001161	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1029718001162	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1029718001163	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1029718001164	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1029718001165	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1029718001166	Peptidase family M28; Region: Peptidase_M28; pfam04389
1029718001167	metal binding site [ion binding]; metal-binding site
1029718001168	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1029718001169	active site
1029718001170	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1029718001171	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1029718001172	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1029718001173	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1029718001174	active site
1029718001175	dimer interface [polypeptide binding]; other site
1029718001176	motif 1; other site
1029718001177	motif 2; other site
1029718001178	motif 3; other site
1029718001179	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1029718001180	anticodon binding site; other site
1029718001181	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1029718001182	oligomerisation interface [polypeptide binding]; other site
1029718001183	mobile loop; other site
1029718001184	roof hairpin; other site
1029718001185	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1029718001186	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1029718001187	ring oligomerisation interface [polypeptide binding]; other site
1029718001188	ATP/Mg binding site [chemical binding]; other site
1029718001189	stacking interactions; other site
1029718001190	hinge regions; other site
1029718001191	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1029718001192	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1029718001193	dimer interface [polypeptide binding]; other site
1029718001194	putative CheW interface [polypeptide binding]; other site
1029718001195	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1029718001196	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718001197	dimer interface [polypeptide binding]; other site
1029718001198	conserved gate region; other site
1029718001199	putative PBP binding loops; other site
1029718001200	ABC-ATPase subunit interface; other site
1029718001201	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1029718001202	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1029718001203	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718001204	dimer interface [polypeptide binding]; other site
1029718001205	conserved gate region; other site
1029718001206	putative PBP binding loops; other site
1029718001207	ABC-ATPase subunit interface; other site
1029718001208	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1029718001209	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1029718001210	Walker A/P-loop; other site
1029718001211	ATP binding site [chemical binding]; other site
1029718001212	Q-loop/lid; other site
1029718001213	ABC transporter signature motif; other site
1029718001214	Walker B; other site
1029718001215	D-loop; other site
1029718001216	H-loop/switch region; other site
1029718001217	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1029718001218	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1029718001219	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1029718001220	Walker A/P-loop; other site
1029718001221	ATP binding site [chemical binding]; other site
1029718001222	Q-loop/lid; other site
1029718001223	ABC transporter signature motif; other site
1029718001224	Walker B; other site
1029718001225	D-loop; other site
1029718001226	H-loop/switch region; other site
1029718001227	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1029718001228	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1029718001229	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1029718001230	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1029718001231	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1029718001232	Flavoprotein; Region: Flavoprotein; cl08021
1029718001233	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1029718001234	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
1029718001235	folate binding site [chemical binding]; other site
1029718001236	NADP+ binding site [chemical binding]; other site
1029718001237	Thymidylate synthase [Nucleotide transport and metabolism]; Region: ThyA; COG0207
1029718001238	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
1029718001239	dimerization interface [polypeptide binding]; other site
1029718001240	active site
1029718001241	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1029718001242	rhamnulokinase; Region: rhamnulo_kin; TIGR02627
1029718001243	nucleotide binding site [chemical binding]; other site
1029718001244	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1029718001245	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1029718001246	active site
1029718001247	catalytic tetrad [active]
1029718001248	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1029718001249	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1029718001250	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
1029718001251	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1029718001252	The Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT; cl04176
1029718001253	type VII secretion protein EssC, C-terminal domain; Region: T7_EssCb_Firm; TIGR03928
1029718001254	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1029718001255	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1029718001256	Cytidylate kinase-like family; Region: Cytidylate_kin2; pfam13189
1029718001257	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1029718001258	active site
1029718001259	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1029718001260	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718001261	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718001262	active site
1029718001263	phosphorylation site [posttranslational modification]
1029718001264	intermolecular recognition site; other site
1029718001265	dimerization interface [polypeptide binding]; other site
1029718001266	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718001267	DNA binding site [nucleotide binding]
1029718001268	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718001269	HAMP domain; Region: HAMP; pfam00672
1029718001270	dimerization interface [polypeptide binding]; other site
1029718001271	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718001272	dimer interface [polypeptide binding]; other site
1029718001273	phosphorylation site [posttranslational modification]
1029718001274	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718001275	ATP binding site [chemical binding]; other site
1029718001276	Mg2+ binding site [ion binding]; other site
1029718001277	G-X-G motif; other site
1029718001278	Glycosyl hydrolases related to GH101 family; Region: GHL; pfam11308
1029718001279	Hemerythrin HHE cation binding domain; Region: Hemerythrin; pfam01814
1029718001280	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
1029718001281	iron-sulfur cluster repair di-iron protein; Region: FeS_repair_RIC; TIGR03652
1029718001282	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
1029718001283	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1029718001284	Peptidase family M23; Region: Peptidase_M23; pfam01551
1029718001285	YtxC-like family; Region: YtxC; pfam08812
1029718001286	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
1029718001287	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
1029718001288	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1029718001289	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1029718001290	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1029718001291	23S rRNA binding site [nucleotide binding]; other site
1029718001292	L21 binding site [polypeptide binding]; other site
1029718001293	L13 binding site [polypeptide binding]; other site
1029718001294	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1029718001295	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1029718001296	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1029718001297	TrkA-N domain; Region: TrkA_N; pfam02254
1029718001298	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1029718001299	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1029718001300	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1029718001301	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1029718001302	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1029718001303	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1029718001304	dimer interface [polypeptide binding]; other site
1029718001305	motif 1; other site
1029718001306	active site
1029718001307	motif 2; other site
1029718001308	motif 3; other site
1029718001309	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1029718001310	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1029718001311	putative tRNA-binding site [nucleotide binding]; other site
1029718001312	B3/4 domain; Region: B3_4; pfam03483
1029718001313	tRNA synthetase B5 domain; Region: B5; smart00874
1029718001314	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1029718001315	dimer interface [polypeptide binding]; other site
1029718001316	motif 1; other site
1029718001317	motif 3; other site
1029718001318	motif 2; other site
1029718001319	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
1029718001320	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
1029718001321	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1029718001322	putative ligand binding site [chemical binding]; other site
1029718001323	putative NAD binding site [chemical binding]; other site
1029718001324	catalytic site [active]
1029718001325	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718001326	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718001327	Bacteriophage holin; Region: Phage_holin_1; cl02344
1029718001328	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1029718001329	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1029718001330	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1029718001331	Dihydrodipicolinate synthase/N-acetylneuraminate lyase [Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane]; Region: DapA; COG0329
1029718001332	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1029718001333	dimer interface [polypeptide binding]; other site
1029718001334	active site
1029718001335	catalytic residue [active]
1029718001336	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1029718001337	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1029718001338	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1029718001339	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1029718001340	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1029718001341	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1029718001342	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1029718001343	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1029718001344	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1029718001345	TPP-binding site; other site
1029718001346	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1029718001347	PYR/PP interface [polypeptide binding]; other site
1029718001348	dimer interface [polypeptide binding]; other site
1029718001349	TPP binding site [chemical binding]; other site
1029718001350	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1029718001351	Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026
1029718001352	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1029718001353	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1029718001354	Peptidase M16C associated; Region: M16C_assoc; pfam08367
1029718001355	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1029718001356	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1029718001357	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1029718001358	substrate binding site [chemical binding]; other site
1029718001359	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1029718001360	tyrosine phosphatase, pseudogene
1029718001361	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
1029718001362	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1029718001363	DHH family; Region: DHH; pfam01368
1029718001364	DHHA1 domain; Region: DHHA1; pfam02272
1029718001365	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718001366	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718001367	dimer interface [polypeptide binding]; other site
1029718001368	phosphorylation site [posttranslational modification]
1029718001369	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718001370	ATP binding site [chemical binding]; other site
1029718001371	Mg2+ binding site [ion binding]; other site
1029718001372	G-X-G motif; other site
1029718001373	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Reviewed; Region: PRK12446
1029718001374	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1029718001375	active site
1029718001376	homodimer interface [polypeptide binding]; other site
1029718001377	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1029718001378	TPR motif; other site
1029718001379	TPR repeat; Region: TPR_11; pfam13414
1029718001380	binding surface
1029718001381	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1029718001382	binding surface
1029718001383	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1029718001384	TPR motif; other site
1029718001385	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718001386	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718001387	Cell division protein ZapA; Region: ZapA; pfam05164
1029718001388	Rubrerythrin [Energy production and conversion]; Region: COG1592
1029718001389	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1029718001390	binuclear metal center [ion binding]; other site
1029718001391	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1029718001392	iron binding site [ion binding]; other site
1029718001393	Cation efflux family; Region: Cation_efflux; pfam01545
1029718001394	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1029718001395	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1029718001396	Transglycosylase; Region: Transgly; pfam00912
1029718001397	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1029718001398	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1029718001399	Peptidase family U32; Region: Peptidase_U32; pfam01136
1029718001400	Collagenase; Region: DUF3656; pfam12392
1029718001401	Peptidase family U32; Region: Peptidase_U32; cl03113
1029718001402	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1029718001403	MutS domain III; Region: MutS_III; pfam05192
1029718001404	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718001405	Walker A/P-loop; other site
1029718001406	ATP binding site [chemical binding]; other site
1029718001407	Q-loop/lid; other site
1029718001408	ABC transporter signature motif; other site
1029718001409	Walker B; other site
1029718001410	D-loop; other site
1029718001411	H-loop/switch region; other site
1029718001412	Smr domain; Region: Smr; pfam01713
1029718001413	YabP family; Region: YabP; cl06766
1029718001414	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
1029718001415	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
1029718001416	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1029718001417	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1029718001418	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718001419	Zn2+ binding site [ion binding]; other site
1029718001420	Mg2+ binding site [ion binding]; other site
1029718001421	metal-binding heat shock protein; Provisional; Region: PRK00016
1029718001422	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
1029718001423	PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like phosphatase domains appear fused to E. coli DAGK-like trans-membrane diacylglycerol kinase domains. The cellular function of these architectures remains to be...; Region: PAP2_diacylglycerolkinase; cd03383
1029718001424	active site
1029718001425	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1029718001426	active site
1029718001427	catalytic motif [active]
1029718001428	Zn binding site [ion binding]; other site
1029718001429	GTPase Era; Reviewed; Region: era; PRK00089
1029718001430	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1029718001431	G1 box; other site
1029718001432	GTP/Mg2+ binding site [chemical binding]; other site
1029718001433	Switch I region; other site
1029718001434	G2 box; other site
1029718001435	Switch II region; other site
1029718001436	G3 box; other site
1029718001437	G4 box; other site
1029718001438	G5 box; other site
1029718001439	KH domain; Region: KH_2; pfam07650
1029718001440	Recombination protein O N terminal; Region: RecO_N; pfam11967
1029718001441	DNA repair protein RecO; Region: reco; TIGR00613
1029718001442	Recombination protein O C terminal; Region: RecO_C; pfam02565
1029718001443	pyruvate phosphate dikinase; Provisional; Region: PRK09279
1029718001444	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1029718001445	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1029718001446	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1029718001447	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1029718001448	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1029718001449	substrate binding site [chemical binding]; other site
1029718001450	DNA primase; Validated; Region: dnaG; PRK05667
1029718001451	CHC2 zinc finger; Region: zf-CHC2; cl17510
1029718001452	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1029718001453	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1029718001454	active site
1029718001455	metal binding site [ion binding]; metal-binding site
1029718001456	interdomain interaction site; other site
1029718001457	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1029718001458	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1029718001459	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1029718001460	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1029718001461	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718001462	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1029718001463	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718001464	DNA binding residues [nucleotide binding]
1029718001465	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1029718001466	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718001467	S-adenosylmethionine binding site [chemical binding]; other site
1029718001468	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1029718001469	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1029718001470	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1029718001471	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
1029718001472	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
1029718001473	active site
1029718001474	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1029718001475	Part of AAA domain; Region: AAA_19; pfam13245
1029718001476	AAA domain; Region: AAA_14; pfam13173
1029718001477	Family description; Region: UvrD_C_2; pfam13538
1029718001478	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1029718001479	D-Alanine aminotransferase (D-AAT_like): D-amino acid aminotransferase catalyzes transamination between D-amino acids and their respective alpha-keto acids. It plays a major role in the synthesis of bacterial cell wall components like D-alanine and...; Region: D-AAT_like; cd01558
1029718001480	homodimer interface [polypeptide binding]; other site
1029718001481	substrate-cofactor binding pocket; other site
1029718001482	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718001483	catalytic residue [active]
1029718001484	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1029718001485	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718001486	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718001487	DNA binding residues [nucleotide binding]
1029718001488	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
1029718001489	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
1029718001490	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1029718001491	active site residue [active]
1029718001492	Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis]; Region: YSH1; COG1236
1029718001493	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1029718001494	Beta-Casp domain; Region: Beta-Casp; smart01027
1029718001495	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1029718001496	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1029718001497	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1029718001498	dimer interface [polypeptide binding]; other site
1029718001499	PYR/PP interface [polypeptide binding]; other site
1029718001500	TPP binding site [chemical binding]; other site
1029718001501	substrate binding site [chemical binding]; other site
1029718001502	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1029718001503	Domain of unknown function; Region: EKR; smart00890
1029718001504	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1029718001505	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1029718001506	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1029718001507	TPP-binding site [chemical binding]; other site
1029718001508	dimer interface [polypeptide binding]; other site
1029718001509	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1029718001510	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; cl07971
1029718001511	Protein of unknown function (DUF1450); Region: DUF1450; cl11488
1029718001512	Phosphoserine phosphatase [Amino acid transport and metabolism]; Region: SerB; COG0560
1029718001513	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1029718001514	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1029718001515	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1029718001516	substrate-cofactor binding pocket; other site
1029718001517	homodimer interface [polypeptide binding]; other site
1029718001518	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718001519	catalytic residue [active]
1029718001520	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cd00588
1029718001521	CheD chemotactic sensory transduction; Region: CheD; cl00810
1029718001522	Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain [Cell motility and secretion / Signal transduction mechanisms]; Region: CheB; COG2201
1029718001523	CheB methylesterase; Region: CheB_methylest; pfam01339
1029718001524	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1029718001525	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1029718001526	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1029718001527	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1029718001528	putative binding surface; other site
1029718001529	active site
1029718001530	P2 response regulator binding domain; Region: P2; pfam07194
1029718001531	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1029718001532	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718001533	ATP binding site [chemical binding]; other site
1029718001534	Mg2+ binding site [ion binding]; other site
1029718001535	G-X-G motif; other site
1029718001536	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1029718001537	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1029718001538	CheC-like family; Region: CheC; pfam04509
1029718001539	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1029718001540	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718001541	active site
1029718001542	phosphorylation site [posttranslational modification]
1029718001543	intermolecular recognition site; other site
1029718001544	dimerization interface [polypeptide binding]; other site
1029718001545	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
1029718001546	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1029718001547	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1029718001548	flagellar motor switch protein; Validated; Region: PRK08119
1029718001549	Chemotaxis phosphatase CheX; Region: CheX; cl15816
1029718001550	Chemotaxis phosphatase CheX; Region: CheX; cl15816
1029718001551	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
1029718001552	FlgN protein; Region: FlgN; pfam05130
1029718001553	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1029718001554	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1029718001555	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
1029718001556	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1029718001557	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1029718001558	FliW protein; Region: FliW; cl00740
1029718001559	carbon storage regulator; Provisional; Region: PRK01712
1029718001560	Flagellar protein FliS; Region: FliS; cl00654
1029718001561	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1029718001562	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1029718001563	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636
1029718001564	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1029718001565	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1029718001566	flagellin; Reviewed; Region: PRK08869
1029718001567	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1029718001568	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1029718001569	flagellin; Reviewed; Region: PRK08869
1029718001570	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1029718001571	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1029718001572	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1029718001573	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1029718001574	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; cl06814
1029718001575	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
1029718001576	sporulation protein YtfJ; Region: spore_ytfJ; TIGR02874
1029718001577	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1029718001578	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1029718001579	DNA binding residues [nucleotide binding]
1029718001580	putative dimer interface [polypeptide binding]; other site
1029718001581	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1029718001582	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1029718001583	active site
1029718001584	catalytic tetrad [active]
1029718001585	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1029718001586	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1029718001587	active site
1029718001588	catalytic tetrad [active]
1029718001589	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
1029718001590	ribose-5-phosphate isomerase B; Provisional; Region: PRK05571
1029718001591	hypothetical protein; Provisional; Region: PRK04323
1029718001592	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1029718001593	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1029718001594	catalytic site [active]
1029718001595	G-X2-G-X-G-K; other site
1029718001596	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1029718001597	primosome assembly protein PriA; Validated; Region: PRK05580
1029718001598	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718001599	ATP binding site [chemical binding]; other site
1029718001600	putative Mg++ binding site [ion binding]; other site
1029718001601	helicase superfamily c-terminal domain; Region: HELICc; smart00490
1029718001602	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1029718001603	active site
1029718001604	catalytic residues [active]
1029718001605	metal binding site [ion binding]; metal-binding site
1029718001606	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1029718001607	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1029718001608	putative active site [active]
1029718001609	substrate binding site [chemical binding]; other site
1029718001610	putative cosubstrate binding site; other site
1029718001611	catalytic site [active]
1029718001612	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1029718001613	substrate binding site [chemical binding]; other site
1029718001614	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1029718001615	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1029718001616	putative RNA binding site [nucleotide binding]; other site
1029718001617	NusB family; Region: NusB; pfam01029
1029718001618	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718001619	S-adenosylmethionine binding site [chemical binding]; other site
1029718001620	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14454
1029718001621	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718001622	FeS/SAM binding site; other site
1029718001623	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1029718001624	active site
1029718001625	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1029718001626	Catalytic domain of Protein Kinases; Region: PKc; cd00180
1029718001627	active site
1029718001628	ATP binding site [chemical binding]; other site
1029718001629	substrate binding site [chemical binding]; other site
1029718001630	activation loop (A-loop); other site
1029718001631	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1029718001632	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1029718001633	GTPase RsgA; Reviewed; Region: PRK00098
1029718001634	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1029718001635	RNA binding site [nucleotide binding]; other site
1029718001636	homodimer interface [polypeptide binding]; other site
1029718001637	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1029718001638	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1029718001639	GTP/Mg2+ binding site [chemical binding]; other site
1029718001640	G4 box; other site
1029718001641	G5 box; other site
1029718001642	G1 box; other site
1029718001643	Switch I region; other site
1029718001644	G2 box; other site
1029718001645	G3 box; other site
1029718001646	Switch II region; other site
1029718001647	Thiamine pyrophosphokinase; Region: TPK; cd07995
1029718001648	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1029718001649	active site
1029718001650	dimerization interface [polypeptide binding]; other site
1029718001651	thiamine binding site [chemical binding]; other site
1029718001652	Formate/nitrite transporter; Region: Form_Nir_trans; cl00927
1029718001653	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1029718001654	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1029718001655	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1029718001656	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1029718001657	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1029718001658	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1029718001659	hypothetical protein, pseudogene
1029718001660	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1029718001661	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1029718001662	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
1029718001663	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
1029718001664	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1029718001665	Asp23 family; Region: Asp23; cl00574
1029718001666	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1029718001667	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718001668	ATP binding site [chemical binding]; other site
1029718001669	putative Mg++ binding site [ion binding]; other site
1029718001670	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718001671	nucleotide binding region [chemical binding]; other site
1029718001672	ATP-binding site [chemical binding]; other site
1029718001673	N6-adenine-specific methylase [DNA replication, recombination, and repair]; Region: COG0742
1029718001674	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718001675	S-adenosylmethionine binding site [chemical binding]; other site
1029718001676	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1029718001677	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1029718001678	active site
1029718001679	(T/H)XGH motif; other site
1029718001680	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718001681	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1029718001682	active site
1029718001683	motif I; other site
1029718001684	motif II; other site
1029718001685	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718001686	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
1029718001687	Nucleoside recognition; Region: Gate; pfam07670
1029718001688	hypothetical protein; Provisional; Region: PRK13670
1029718001689	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
1029718001690	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
1029718001691	propionate/acetate kinase; Provisional; Region: PRK12379
1029718001692	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1029718001693	nucleotide binding site [chemical binding]; other site
1029718001694	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
1029718001695	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
1029718001696	putative phosphate acyltransferase; Provisional; Region: PRK05331
1029718001697	acyl carrier protein; Provisional; Region: acpP; PRK00982
1029718001698	ribonuclease III; Reviewed; Region: rnc; PRK00102
1029718001699	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1029718001700	dimerization interface [polypeptide binding]; other site
1029718001701	active site
1029718001702	metal binding site [ion binding]; metal-binding site
1029718001703	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1029718001704	dsRNA binding site [nucleotide binding]; other site
1029718001705	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1029718001706	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
1029718001707	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1029718001708	AP (apurinic/apyrimidinic) site pocket; other site
1029718001709	DNA interaction; other site
1029718001710	Metal-binding active site; metal-binding site
1029718001711	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
1029718001712	HI0933-like protein; Region: HI0933_like; pfam03486
1029718001713	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1029718001714	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1029718001715	cytidylate kinase; Provisional; Region: cmk; PRK00023
1029718001716	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1029718001717	CMP-binding site; other site
1029718001718	The sites determining sugar specificity; other site
1029718001719	4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; Reviewed; Region: PRK00087
1029718001720	LytB protein; Region: LYTB; cl00507
1029718001721	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1029718001722	RNA binding site [nucleotide binding]; other site
1029718001723	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1029718001724	RNA binding site [nucleotide binding]; other site
1029718001725	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1029718001726	RNA binding site [nucleotide binding]; other site
1029718001727	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1029718001728	RNA binding site [nucleotide binding]; other site
1029718001729	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
1029718001730	Bacterial RNase HI containing a hybrid binding domain (HBD) at the N-terminus; Region: RNase_HI_bacteria_HBD; cd09277
1029718001731	RNA/DNA hybrid binding site [nucleotide binding]; other site
1029718001732	active site
1029718001733	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK06843
1029718001734	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
1029718001735	active site
1029718001736	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1029718001737	GMP synthase; Reviewed; Region: guaA; PRK00074
1029718001738	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
1029718001739	AMP/PPi binding site [chemical binding]; other site
1029718001740	candidate oxyanion hole; other site
1029718001741	catalytic triad [active]
1029718001742	potential glutamine specificity residues [chemical binding]; other site
1029718001743	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1029718001744	ATP Binding subdomain [chemical binding]; other site
1029718001745	Ligand Binding sites [chemical binding]; other site
1029718001746	Dimerization subdomain; other site
1029718001747	Flagellin and related hook-associated proteins [Cell motility and secretion]; Region: FlgL; COG1344
1029718001748	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1029718001749	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1029718001750	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1029718001751	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1029718001752	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1029718001753	Walker A/P-loop; other site
1029718001754	ATP binding site [chemical binding]; other site
1029718001755	Q-loop/lid; other site
1029718001756	ABC transporter signature motif; other site
1029718001757	Walker B; other site
1029718001758	D-loop; other site
1029718001759	H-loop/switch region; other site
1029718001760	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1029718001761	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718001762	dimer interface [polypeptide binding]; other site
1029718001763	conserved gate region; other site
1029718001764	putative PBP binding loops; other site
1029718001765	ABC-ATPase subunit interface; other site
1029718001766	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1029718001767	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718001768	dimer interface [polypeptide binding]; other site
1029718001769	conserved gate region; other site
1029718001770	ABC-ATPase subunit interface; other site
1029718001771	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
1029718001772	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1029718001773	active site
1029718001774	metal binding site [ion binding]; metal-binding site
1029718001775	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1029718001776	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1029718001777	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1029718001778	active site
1029718001779	catalytic tetrad [active]
1029718001780	Uncharacterized conserved protein [Function unknown]; Region: COG3589
1029718001781	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
1029718001782	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1029718001783	active site
1029718001784	phosphorylation site [posttranslational modification]
1029718001785	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
1029718001786	active site
1029718001787	P-loop; other site
1029718001788	phosphorylation site [posttranslational modification]
1029718001789	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
1029718001790	Phosphotransferase system, EIIC; Region: PTS_EIIC; pfam02378
1029718001791	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
1029718001792	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
1029718001793	putative substrate binding site [chemical binding]; other site
1029718001794	putative ATP binding site [chemical binding]; other site
1029718001795	transcription antitermination factor NusB; Region: nusB; TIGR01951
1029718001796	putative RNA binding site [nucleotide binding]; other site
1029718001797	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1029718001798	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1029718001799	generic binding surface II; other site
1029718001800	generic binding surface I; other site
1029718001801	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cd00306
1029718001802	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
1029718001803	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1029718001804	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1029718001805	substrate binding pocket [chemical binding]; other site
1029718001806	chain length determination region; other site
1029718001807	substrate-Mg2+ binding site; other site
1029718001808	catalytic residues [active]
1029718001809	aspartate-rich region 1; other site
1029718001810	active site lid residues [active]
1029718001811	aspartate-rich region 2; other site
1029718001812	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1029718001813	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718001814	RNA binding surface [nucleotide binding]; other site
1029718001815	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1029718001816	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1029718001817	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1029718001818	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1029718001819	arginine repressor; Provisional; Region: argR; PRK00441
1029718001820	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1029718001821	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1029718001822	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1029718001823	Walker A/P-loop; other site
1029718001824	ATP binding site [chemical binding]; other site
1029718001825	Q-loop/lid; other site
1029718001826	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1029718001827	ABC transporter signature motif; other site
1029718001828	Walker B; other site
1029718001829	D-loop; other site
1029718001830	H-loop/switch region; other site
1029718001831	stage IV sporulation protein B; Region: spore_IV_B; TIGR02860
1029718001832	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1029718001833	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
1029718001834	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
1029718001835	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718001836	active site
1029718001837	phosphorylation site [posttranslational modification]
1029718001838	intermolecular recognition site; other site
1029718001839	dimerization interface [polypeptide binding]; other site
1029718001840	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
1029718001841	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1029718001842	intersubunit interface [polypeptide binding]; other site
1029718001843	active site
1029718001844	catalytic residue [active]
1029718001845	SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase; cl01053
1029718001846	active site
1029718001847	catalytic triad [active]
1029718001848	oxyanion hole [active]
1029718001849	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1029718001850	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1029718001851	Walker A/P-loop; other site
1029718001852	ATP binding site [chemical binding]; other site
1029718001853	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1029718001854	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1029718001855	ABC transporter signature motif; other site
1029718001856	Walker B; other site
1029718001857	D-loop; other site
1029718001858	H-loop/switch region; other site
1029718001859	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1029718001860	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1029718001861	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1029718001862	P loop; other site
1029718001863	GTP binding site [chemical binding]; other site
1029718001864	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2739; cl17893
1029718001865	signal recognition particle protein; Provisional; Region: PRK10867
1029718001866	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1029718001867	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1029718001868	P loop; other site
1029718001869	GTP binding site [chemical binding]; other site
1029718001870	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1029718001871	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1029718001872	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1029718001873	RimM N-terminal domain; Region: RimM; pfam01782
1029718001874	PRC-barrel domain; Region: PRC; pfam05239
1029718001875	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1029718001876	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1029718001877	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1029718001878	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1029718001879	GTP/Mg2+ binding site [chemical binding]; other site
1029718001880	G4 box; other site
1029718001881	G5 box; other site
1029718001882	G1 box; other site
1029718001883	Switch I region; other site
1029718001884	G2 box; other site
1029718001885	G3 box; other site
1029718001886	Switch II region; other site
1029718001887	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1029718001888	RNA/DNA hybrid binding site [nucleotide binding]; other site
1029718001889	active site
1029718001890	NADH oxidase, pseudogene
1029718001891	hypothetical protein; Reviewed; Region: PRK12497
1029718001892	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
1029718001893	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
1029718001894	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1029718001895	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1029718001896	hypothetical protein, pseudogene
1029718001897	HsdR family type I site-specific deoxyribonuclease, partial, pseudogene
1029718001898	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
1029718001899	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1029718001900	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
1029718001901	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
1029718001902	ligand binding site [chemical binding]; other site
1029718001903	dimerization interface [polypeptide binding]; other site
1029718001904	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1029718001905	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
1029718001906	TM-ABC transporter signature motif; other site
1029718001907	ribose ABC transporter ATP-binding protein, pseudogene
1029718001908	D-ribose pyranase; Provisional; Region: PRK11797
1029718001909	Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; Region: RbsK; COG0524
1029718001910	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
1029718001911	substrate binding site [chemical binding]; other site
1029718001912	dimer interface [polypeptide binding]; other site
1029718001913	ATP binding site [chemical binding]; other site
1029718001914	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1029718001915	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1029718001916	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
1029718001917	CRISPR-associated protein (Cas_Cas5); Region: Cas_Cas5d; pfam09704
1029718001918	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-C; cd09651
1029718001919	CRISPR/Cas system-associated protein Cas8c; Region: Cas8c_I-C; cl12004
1029718001920	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
1029718001921	CRISPR/Cas system-associated protein Cas4; Region: Cas4_I-A_I-B_I-C_I-D_II-B; cl00641
1029718001922	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-C; cd09721
1029718001923	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1029718001924	Uncharacterized protein family (UPF0150); Region: UPF0150; pfam03681
1029718001925	Post-segregation antitoxin CcdA; Region: CcdA; cl02188
1029718001926	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1029718001927	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1029718001928	active site turn [active]
1029718001929	phosphorylation site [posttranslational modification]
1029718001930	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1029718001931	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1029718001932	HPr interaction site; other site
1029718001933	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1029718001934	active site
1029718001935	phosphorylation site [posttranslational modification]
1029718001936	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1029718001937	beta-galactosidase; Region: BGL; TIGR03356
1029718001938	Protein of unknown function (DUF1624); Region: DUF1624; cl01394
1029718001939	Bacterial protein of unknown function (DUF898); Region: DUF898; cl01738
1029718001940	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1029718001941	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1029718001942	Protein of unknown function (DUF2871); Region: DUF2871; pfam11070
1029718001943	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1029718001944	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
1029718001945	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
1029718001946	active site turn [active]
1029718001947	phosphorylation site [posttranslational modification]
1029718001948	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
1029718001949	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
1029718001950	HPr interaction site; other site
1029718001951	glycerol kinase (GK) interaction site [polypeptide binding]; other site
1029718001952	active site
1029718001953	phosphorylation site [posttranslational modification]
1029718001954	beta-glucosidas, C-terminal part, pseudogene
1029718001955	transcriptional antiterminator BglG; Provisional; Region: PRK09772
1029718001956	CAT RNA binding domain; Region: CAT_RBD; smart01061
1029718001957	PRD domain; Region: PRD; pfam00874
1029718001958	PRD domain; Region: PRD; pfam00874
1029718001959	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
1029718001960	HTH domain; Region: HTH_11; pfam08279
1029718001961	PRD domain; Region: PRD; pfam00874
1029718001962	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
1029718001963	active site
1029718001964	P-loop; other site
1029718001965	phosphorylation site [posttranslational modification]
1029718001966	Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr; Region: PTPc; cl00053
1029718001967	active site
1029718001968	catalytic residues [active]
1029718001969	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1029718001970	active site
1029718001971	phosphorylation site [posttranslational modification]
1029718001972	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1029718001973	active site
1029718001974	phosphorylation site [posttranslational modification]
1029718001975	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
1029718001976	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1029718001977	active site
1029718001978	P-loop; other site
1029718001979	phosphorylation site [posttranslational modification]
1029718001980	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1029718001981	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718001982	S-adenosylmethionine binding site [chemical binding]; other site
1029718001983	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1029718001984	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1029718001985	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1029718001986	putative active site [active]
1029718001987	catalytic site [active]
1029718001988	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1029718001989	putative active site [active]
1029718001990	catalytic site [active]
1029718001991	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
1029718001992	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1029718001993	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718001994	Walker A motif; other site
1029718001995	ATP binding site [chemical binding]; other site
1029718001996	Walker B motif; other site
1029718001997	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
1029718001998	DNA protecting protein DprA; Region: dprA; TIGR00732
1029718001999	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
1029718002000	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1029718002001	putative DNA binding site [nucleotide binding]; other site
1029718002002	dimerization interface [polypeptide binding]; other site
1029718002003	putative Zn2+ binding site [ion binding]; other site
1029718002004	DNA topoisomerase I; Validated; Region: PRK05582
1029718002005	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1029718002006	active site
1029718002007	interdomain interaction site; other site
1029718002008	putative metal-binding site [ion binding]; other site
1029718002009	nucleotide binding site [chemical binding]; other site
1029718002010	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1029718002011	domain I; other site
1029718002012	DNA binding groove [nucleotide binding]
1029718002013	phosphate binding site [ion binding]; other site
1029718002014	domain II; other site
1029718002015	domain III; other site
1029718002016	nucleotide binding site [chemical binding]; other site
1029718002017	catalytic site [active]
1029718002018	domain IV; other site
1029718002019	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1029718002020	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1029718002021	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1029718002022	rRNA interaction site [nucleotide binding]; other site
1029718002023	S8 interaction site; other site
1029718002024	putative laminin-1 binding site; other site
1029718002025	elongation factor Ts; Provisional; Region: tsf; PRK09377
1029718002026	UBA/TS-N domain; Region: UBA; pfam00627
1029718002027	Elongation factor TS; Region: EF_TS; pfam00889
1029718002028	Elongation factor TS; Region: EF_TS; pfam00889
1029718002029	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1029718002030	putative nucleotide binding site [chemical binding]; other site
1029718002031	uridine monophosphate binding site [chemical binding]; other site
1029718002032	homohexameric interface [polypeptide binding]; other site
1029718002033	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1029718002034	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1029718002035	hinge region; other site
1029718002036	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1029718002037	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1029718002038	catalytic residue [active]
1029718002039	putative FPP diphosphate  binding site; other site
1029718002040	putative FPP binding hydrophobic cleft; other site
1029718002041	dimer interface [polypeptide binding]; other site
1029718002042	putative IPP diphosphate binding site; other site
1029718002043	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1029718002044	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1029718002045	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1029718002046	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1029718002047	active site
1029718002048	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1029718002049	protein binding site [polypeptide binding]; other site
1029718002050	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1029718002051	putative substrate binding region [chemical binding]; other site
1029718002052	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1029718002053	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1029718002054	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1029718002055	DNA polymerase III PolC; Validated; Region: polC; PRK00448
1029718002056	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
1029718002057	generic binding surface II; other site
1029718002058	generic binding surface I; other site
1029718002059	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1029718002060	active site
1029718002061	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1029718002062	active site
1029718002063	catalytic site [active]
1029718002064	substrate binding site [chemical binding]; other site
1029718002065	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
1029718002066	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1029718002067	Sm and related proteins; Region: Sm_like; cl00259
1029718002068	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1029718002069	putative oligomer interface [polypeptide binding]; other site
1029718002070	putative RNA binding site [nucleotide binding]; other site
1029718002071	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1029718002072	NusA N-terminal domain; Region: NusA_N; pfam08529
1029718002073	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1029718002074	RNA binding site [nucleotide binding]; other site
1029718002075	homodimer interface [polypeptide binding]; other site
1029718002076	NusA-like KH domain; Region: KH_5; pfam13184
1029718002077	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1029718002078	G-X-X-G motif; other site
1029718002079	Protein of unknown function (DUF448); Region: DUF448; pfam04296
1029718002080	putative RNA binding cleft [nucleotide binding]; other site
1029718002081	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1029718002082	translation initiation factor IF-2; Region: IF-2; TIGR00487
1029718002083	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1029718002084	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1029718002085	G1 box; other site
1029718002086	putative GEF interaction site [polypeptide binding]; other site
1029718002087	GTP/Mg2+ binding site [chemical binding]; other site
1029718002088	Switch I region; other site
1029718002089	G2 box; other site
1029718002090	G3 box; other site
1029718002091	Switch II region; other site
1029718002092	G4 box; other site
1029718002093	G5 box; other site
1029718002094	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1029718002095	Translation-initiation factor 2; Region: IF-2; pfam11987
1029718002096	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1029718002097	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1029718002098	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1029718002099	DHH family; Region: DHH; pfam01368
1029718002100	DHHA1 domain; Region: DHHA1; pfam02272
1029718002101	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
1029718002102	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1029718002103	RNA binding site [nucleotide binding]; other site
1029718002104	active site
1029718002105	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1029718002106	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1029718002107	active site
1029718002108	Riboflavin kinase; Region: Flavokinase; pfam01687
1029718002109	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1029718002110	16S/18S rRNA binding site [nucleotide binding]; other site
1029718002111	S13e-L30e interaction site [polypeptide binding]; other site
1029718002112	25S rRNA binding site [nucleotide binding]; other site
1029718002113	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1029718002114	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1029718002115	RNase E interface [polypeptide binding]; other site
1029718002116	trimer interface [polypeptide binding]; other site
1029718002117	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1029718002118	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1029718002119	RNase E interface [polypeptide binding]; other site
1029718002120	trimer interface [polypeptide binding]; other site
1029718002121	active site
1029718002122	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1029718002123	RNA binding site [nucleotide binding]; other site
1029718002124	domain interface; other site
1029718002125	Protein implicated in RNA metabolism, contains PRC-barrel domain [General    function prediction only]; Region: COG1873; cl17889
1029718002126	aspartate kinase I; Reviewed; Region: PRK08210
1029718002127	Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that...; Region: AAK; cl00452
1029718002128	nucleotide binding site [chemical binding]; other site
1029718002129	substrate binding site [chemical binding]; other site
1029718002130	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1029718002131	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1029718002132	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1029718002133	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1029718002134	active site
1029718002135	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
1029718002136	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1029718002137	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1029718002138	This domain directs oriented DNA translocation and forms a winged helix structure; Region: Ftsk_gamma; smart00843
1029718002139	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1029718002140	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1029718002141	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002142	FeS/SAM binding site; other site
1029718002143	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1029718002144	recombinase A; Provisional; Region: recA; PRK09354
1029718002145	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1029718002146	hexamer interface [polypeptide binding]; other site
1029718002147	Walker A motif; other site
1029718002148	ATP binding site [chemical binding]; other site
1029718002149	Walker B motif; other site
1029718002150	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
1029718002151	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1029718002152	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718002153	Zn2+ binding site [ion binding]; other site
1029718002154	Mg2+ binding site [ion binding]; other site
1029718002155	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1029718002156	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1029718002157	dimerization domain swap beta strand [polypeptide binding]; other site
1029718002158	regulatory protein interface [polypeptide binding]; other site
1029718002159	active site
1029718002160	regulatory phosphorylation site [posttranslational modification]; other site
1029718002161	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1029718002162	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1029718002163	active site
1029718002164	DNA binding site [nucleotide binding]
1029718002165	Int/Topo IB signature motif; other site
1029718002166	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1029718002167	Aluminium resistance protein; Region: Alum_res; pfam06838
1029718002168	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1029718002169	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1029718002170	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1029718002171	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718002172	ATP binding site [chemical binding]; other site
1029718002173	Mg2+ binding site [ion binding]; other site
1029718002174	G-X-G motif; other site
1029718002175	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1029718002176	ATP binding site [chemical binding]; other site
1029718002177	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1029718002178	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1029718002179	MutS domain I; Region: MutS_I; pfam01624
1029718002180	MutS domain II; Region: MutS_II; pfam05188
1029718002181	MutS domain III; Region: MutS_III; pfam05192
1029718002182	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1029718002183	Walker A/P-loop; other site
1029718002184	ATP binding site [chemical binding]; other site
1029718002185	Q-loop/lid; other site
1029718002186	ABC transporter signature motif; other site
1029718002187	Walker B; other site
1029718002188	D-loop; other site
1029718002189	H-loop/switch region; other site
1029718002190	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328
1029718002191	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1029718002192	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
1029718002193	FeS/SAM binding site; other site
1029718002194	TRAM domain; Region: TRAM; pfam01938
1029718002195	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1029718002196	active site
1029718002197	catalytic site [active]
1029718002198	Predicted transcriptional regulators [Transcription]; Region: COG1725
1029718002199	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1029718002200	DNA-binding site [nucleotide binding]; DNA binding site
1029718002201	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1029718002202	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1029718002203	Walker A/P-loop; other site
1029718002204	ATP binding site [chemical binding]; other site
1029718002205	Q-loop/lid; other site
1029718002206	ABC transporter signature motif; other site
1029718002207	Walker B; other site
1029718002208	D-loop; other site
1029718002209	H-loop/switch region; other site
1029718002210	aspartate aminotransferase; Provisional; Region: PRK07568
1029718002211	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1029718002212	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718002213	homodimer interface [polypeptide binding]; other site
1029718002214	catalytic residue [active]
1029718002215	MTH538 TIR-like domain (DUF1863); Region: DUF1863; pfam08937
1029718002216	HsdR family type I site-specific deoxyribonuclease, pseudogene
1029718002217	Protein of unknown function (DUF3801); Region: DUF3801; pfam12687
1029718002218	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
1029718002219	Transthyretin_like.  This domain is present in the transthyretin-like protein (TLP) family which includes transthyretin (TTR) and a transthyretin-related protein called 5-hydroxyisourate hydrolase (HIUase).  TTR and HIUase are homotetrameric proteins...; Region: Transthyretin_like; cl17222
1029718002220	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1029718002221	active site
1029718002222	ADP-ribosylating toxin turn-turn motif; other site
1029718002223	prophage SFBMP3, partial
1029718002224	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1029718002225	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1029718002226	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718002227	non-specific DNA binding site [nucleotide binding]; other site
1029718002228	salt bridge; other site
1029718002229	sequence-specific DNA binding site [nucleotide binding]; other site
1029718002230	Uncharacterized conserved protein [Function unknown]; Region: COG4983
1029718002231	D5 N terminal like; Region: D5_N; smart00885
1029718002232	Poxvirus D5 protein-like; Region: Pox_D5; pfam03288
1029718002233	phage major capsid protein, HK97 family; Region: major_cap_HK97; TIGR01554
1029718002234	Phage capsid family; Region: Phage_capsid; pfam05065
1029718002235	integrase, pseudogene
1029718002236	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1029718002237	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
1029718002238	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1029718002239	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1029718002240	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718002241	active site
1029718002242	putative hydrolase; Validated; Region: PRK09248
1029718002243	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1029718002244	active site
1029718002245	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1029718002246	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
1029718002247	gating phenylalanine in ion channel; other site
1029718002248	spore coat protein YsxE; Region: spore_ysxE; TIGR02904
1029718002249	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1029718002250	Endo-beta-N-acetylglucosaminidase D [Carbohydrate transport and metabolism]; Region: COG4724
1029718002251	Endo-beta-N-acetylglucosaminidase (ENGase) hydrolyzes the N-N'-diacetylchitobiosyl core of N-glycosylproteins.  The beta-1,4-glycosyl bond located between two N-acetylglucosamine residues is hydrolyzed such that N-acetylglucosamine 1 remains with...; Region: GH85_ENGase; cd06547
1029718002252	putative active site [active]
1029718002253	FOG: PKD repeat [General function prediction only]; Region: COG3291
1029718002254	polycystic kidney disease I (PKD) domain; similar to other cell-surface modules, with an IG-like fold; domain probably functions as a ligand binding site in protein-protein or protein-carbohydrate interactions; a single instance of the repeat is...; Region: PKD; cd00146
1029718002255	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
1029718002256	sugar binding site [chemical binding]; other site
1029718002257	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1029718002258	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1029718002259	nucleotide binding site [chemical binding]; other site
1029718002260	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
1029718002261	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1029718002262	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1029718002263	Walker A/P-loop; other site
1029718002264	ATP binding site [chemical binding]; other site
1029718002265	Q-loop/lid; other site
1029718002266	ABC transporter signature motif; other site
1029718002267	Walker B; other site
1029718002268	D-loop; other site
1029718002269	H-loop/switch region; other site
1029718002270	Predicted membrane protein [Function unknown]; Region: COG3428
1029718002271	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
1029718002272	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1029718002273	nucleotide binding site [chemical binding]; other site
1029718002274	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1029718002275	Domain of unknown function (DUF3502); Region: DUF3502; pfam12010
1029718002276	N-terminal catalytic domain of endoplasmic reticulum(ER)/cytosolic class II alpha-mannosidases; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_ER_cytosolic; cd10789
1029718002277	active site
1029718002278	catalytic site [active]
1029718002279	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; pfam09261
1029718002280	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
1029718002281	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1029718002282	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718002283	dimer interface [polypeptide binding]; other site
1029718002284	conserved gate region; other site
1029718002285	ABC-ATPase subunit interface; other site
1029718002286	ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism]; Region: LplB; COG4209
1029718002287	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718002288	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1029718002289	ABC-ATPase subunit interface; other site
1029718002290	Response regulator receiver domain; Region: Response_reg; pfam00072
1029718002291	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718002292	active site
1029718002293	phosphorylation site [posttranslational modification]
1029718002294	intermolecular recognition site; other site
1029718002295	dimerization interface [polypeptide binding]; other site
1029718002296	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1029718002297	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1029718002298	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1029718002299	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1029718002300	dimerization interface [polypeptide binding]; other site
1029718002301	Histidine kinase; Region: His_kinase; pfam06580
1029718002302	Uncharacterized conserved protein [Function unknown]; Region: COG3538
1029718002303	Protein of unknown function (DUF1237); Region: DUF1237; pfam06824
1029718002304	Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: COG1501
1029718002305	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
1029718002306	Alpha-glucosidase II (alpha-D-glucoside glucohydrolase) is a glycosyl hydrolase family 31 (GH31) enzyme, found in bacteria and plants, which has exo-alpha-1,4-glucosidase and oligo-1,6-glucosidase activities. Alpha-glucosidase II has been characterized...; Region: GH31_glucosidase_II_MalA; cd06604
1029718002307	trimer interface [polypeptide binding]; other site
1029718002308	active site
1029718002309	homohexamer (dimer of homotrimer) interface [polypeptide binding]; other site
1029718002310	catalytic site [active]
1029718002311	Glutamine Amidotransferase (GATase_I) involved in pyridoxine biosynthesis; Region: GATase1_PB; cd01749
1029718002312	predicted active site [active]
1029718002313	catalytic triad [active]
1029718002314	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1029718002315	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1029718002316	active site
1029718002317	multimer interface [polypeptide binding]; other site
1029718002318	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: COG0610
1029718002319	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
1029718002320	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718002321	ATP binding site [chemical binding]; other site
1029718002322	putative Mg++ binding site [ion binding]; other site
1029718002323	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718002324	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1029718002325	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718002326	type I restriction system adenine methylase (hsdM); Region: hsdM; TIGR00497
1029718002327	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1029718002328	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1029718002329	P-loop containing region of AAA domain; Region: AAA_29; cl17516
1029718002330	AAA domain; Region: AAA_13; pfam13166
1029718002331	HpaII restriction endonuclease; Region: RE_HpaII; pfam09561
1029718002332	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1029718002333	DNA-methyltransferase (dcm); Region: dcm; TIGR00675
1029718002334	cofactor binding site; other site
1029718002335	DNA binding site [nucleotide binding]
1029718002336	substrate interaction site [chemical binding]; other site
1029718002337	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1029718002338	HsdM N-terminal domain; Region: HsdM_N; pfam12161
1029718002339	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
1029718002340	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
1029718002341	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1029718002342	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1029718002343	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1029718002344	GTP-binding protein Der; Reviewed; Region: PRK00093
1029718002345	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1029718002346	G1 box; other site
1029718002347	GTP/Mg2+ binding site [chemical binding]; other site
1029718002348	Switch I region; other site
1029718002349	G2 box; other site
1029718002350	Switch II region; other site
1029718002351	G3 box; other site
1029718002352	G4 box; other site
1029718002353	G5 box; other site
1029718002354	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1029718002355	G1 box; other site
1029718002356	GTP/Mg2+ binding site [chemical binding]; other site
1029718002357	Switch I region; other site
1029718002358	G2 box; other site
1029718002359	G3 box; other site
1029718002360	Switch II region; other site
1029718002361	G4 box; other site
1029718002362	G5 box; other site
1029718002363	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
1029718002364	Peptidase family M28; Region: Peptidase_M28; pfam04389
1029718002365	metal binding site [ion binding]; metal-binding site
1029718002366	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1029718002367	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718002368	non-specific DNA binding site [nucleotide binding]; other site
1029718002369	salt bridge; other site
1029718002370	sequence-specific DNA binding site [nucleotide binding]; other site
1029718002371	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1029718002372	amidase catalytic site [active]
1029718002373	Zn binding residues [ion binding]; other site
1029718002374	substrate binding site [chemical binding]; other site
1029718002375	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002376	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1029718002377	PhoU domain; Region: PhoU; pfam01895
1029718002378	PhoU domain; Region: PhoU; pfam01895
1029718002379	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1029718002380	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1029718002381	Walker A/P-loop; other site
1029718002382	ATP binding site [chemical binding]; other site
1029718002383	Q-loop/lid; other site
1029718002384	ABC transporter signature motif; other site
1029718002385	Walker B; other site
1029718002386	D-loop; other site
1029718002387	H-loop/switch region; other site
1029718002388	Domain of unknown function (DUF3333); Region: DUF3333; pfam11812
1029718002389	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1029718002390	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718002391	dimer interface [polypeptide binding]; other site
1029718002392	conserved gate region; other site
1029718002393	putative PBP binding loops; other site
1029718002394	ABC-ATPase subunit interface; other site
1029718002395	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1029718002396	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1029718002397	dimer interface [polypeptide binding]; other site
1029718002398	conserved gate region; other site
1029718002399	putative PBP binding loops; other site
1029718002400	ABC-ATPase subunit interface; other site
1029718002401	PBP superfamily domain; Region: PBP_like_2; cl17296
1029718002402	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1029718002403	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718002404	dimer interface [polypeptide binding]; other site
1029718002405	phosphorylation site [posttranslational modification]
1029718002406	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718002407	ATP binding site [chemical binding]; other site
1029718002408	Mg2+ binding site [ion binding]; other site
1029718002409	G-X-G motif; other site
1029718002410	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718002411	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718002412	active site
1029718002413	phosphorylation site [posttranslational modification]
1029718002414	intermolecular recognition site; other site
1029718002415	dimerization interface [polypeptide binding]; other site
1029718002416	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718002417	DNA binding site [nucleotide binding]
1029718002418	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1029718002419	Protein implicated in RNA metabolism, contains PRC-barrel domain [General    function prediction only]; Region: COG1873; cl17889
1029718002420	heavy metal translocating P-type ATPase, pseudogene
1029718002421	sporulation sigma factor SigG; Reviewed; Region: PRK08215
1029718002422	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718002423	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1029718002424	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718002425	DNA binding residues [nucleotide binding]
1029718002426	sporulation sigma factor SigE; Reviewed; Region: PRK08301
1029718002427	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718002428	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718002429	DNA binding residues [nucleotide binding]
1029718002430	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
1029718002431	cell division protein FtsZ; Validated; Region: PRK09330
1029718002432	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1029718002433	nucleotide binding site [chemical binding]; other site
1029718002434	SulA interaction site; other site
1029718002435	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
1029718002436	EpsO protein participates in the methanolan synthesis; Region: EpsO_like; cd06438
1029718002437	DXD motif; other site
1029718002438	pilus retraction protein PilT; Region: pilT_fam; TIGR01420
1029718002439	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1029718002440	Walker A motif; other site
1029718002441	ATP binding site [chemical binding]; other site
1029718002442	Walker B motif; other site
1029718002443	sporulation sigma factor SigK; Reviewed; Region: PRK05803
1029718002444	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718002445	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718002446	DNA binding residues [nucleotide binding]
1029718002447	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
1029718002448	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1029718002449	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1029718002450	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
1029718002451	Peptidase family U32; Region: Peptidase_U32; pfam01136
1029718002452	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1029718002453	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718002454	S-adenosylmethionine binding site [chemical binding]; other site
1029718002455	YceG-like family; Region: YceG; pfam02618
1029718002456	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
1029718002457	dimerization interface [polypeptide binding]; other site
1029718002458	Protein of unknown function (DUF964); Region: DUF964; cl01483
1029718002459	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1029718002460	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1029718002461	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1029718002462	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1029718002463	metal binding site 2 [ion binding]; metal-binding site
1029718002464	putative DNA binding helix; other site
1029718002465	metal binding site 1 [ion binding]; metal-binding site
1029718002466	dimer interface [polypeptide binding]; other site
1029718002467	structural Zn2+ binding site [ion binding]; other site
1029718002468	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1029718002469	hypothetical protein; Provisional; Region: PRK05473
1029718002470	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1029718002471	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1029718002472	motif 1; other site
1029718002473	active site
1029718002474	motif 2; other site
1029718002475	motif 3; other site
1029718002476	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1029718002477	DHHA1 domain; Region: DHHA1; pfam02272
1029718002478	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1029718002479	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1029718002480	Ligand Binding Site [chemical binding]; other site
1029718002481	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1029718002482	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1029718002483	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1029718002484	catalytic residue [active]
1029718002485	Predicted transcriptional regulator [Transcription]; Region: COG1959
1029718002486	Transcriptional regulator; Region: Rrf2; cl17282
1029718002487	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1029718002488	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1029718002489	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1029718002490	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1029718002491	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1029718002492	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1029718002493	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1029718002494	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1029718002495	acetyl-CoA carboxylase, biotin carboxyl carrier protein; Region: BCCP; TIGR00531
1029718002496	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1029718002497	carboxyltransferase (CT) interaction site; other site
1029718002498	biotinylation site [posttranslational modification]; other site
1029718002499	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1029718002500	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1029718002501	dimer interface [polypeptide binding]; other site
1029718002502	active site
1029718002503	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1029718002504	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1029718002505	NAD(P) binding site [chemical binding]; other site
1029718002506	homotetramer interface [polypeptide binding]; other site
1029718002507	homodimer interface [polypeptide binding]; other site
1029718002508	active site
1029718002509	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1029718002510	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1029718002511	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1029718002512	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1029718002513	dimer interface [polypeptide binding]; other site
1029718002514	active site
1029718002515	CoA binding pocket [chemical binding]; other site
1029718002516	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1029718002517	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1029718002518	dimer interface [polypeptide binding]; other site
1029718002519	active site
1029718002520	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1029718002521	folate binding site [chemical binding]; other site
1029718002522	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1029718002523	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1029718002524	dimer interface [polypeptide binding]; other site
1029718002525	anticodon binding site; other site
1029718002526	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1029718002527	homodimer interface [polypeptide binding]; other site
1029718002528	motif 1; other site
1029718002529	active site
1029718002530	motif 2; other site
1029718002531	GAD domain; Region: GAD; pfam02938
1029718002532	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1029718002533	active site
1029718002534	motif 3; other site
1029718002535	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1029718002536	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1029718002537	dimer interface [polypeptide binding]; other site
1029718002538	motif 1; other site
1029718002539	active site
1029718002540	motif 2; other site
1029718002541	motif 3; other site
1029718002542	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1029718002543	anticodon binding site; other site
1029718002544	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1029718002545	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1029718002546	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1029718002547	Zn2+ binding site [ion binding]; other site
1029718002548	Mg2+ binding site [ion binding]; other site
1029718002549	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1029718002550	synthetase active site [active]
1029718002551	NTP binding site [chemical binding]; other site
1029718002552	metal binding site [ion binding]; metal-binding site
1029718002553	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1029718002554	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1029718002555	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718002556	active site
1029718002557	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1029718002558	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1029718002559	Protein export membrane protein; Region: SecD_SecF; pfam02355
1029718002560	protein-export membrane protein SecD; Region: secD; TIGR01129
1029718002561	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1029718002562	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
1029718002563	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002564	FeS/SAM binding site; other site
1029718002565	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1029718002566	Protein of unknown function (DUF4001); Region: DUF4001; pfam13165
1029718002567	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002568	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
1029718002569	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1029718002570	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1029718002571	S-adenosylmethionine:tRNA ribosyltransferase-isomerase, pseudogene
1029718002572	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1029718002573	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718002574	Walker A motif; other site
1029718002575	ATP binding site [chemical binding]; other site
1029718002576	Walker B motif; other site
1029718002577	arginine finger; other site
1029718002578	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1029718002579	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1029718002580	RuvA N terminal domain; Region: RuvA_N; pfam01330
1029718002581	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1029718002582	hypothetical protein, pseudogene
1029718002583	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in mouse RS21-C6 protein and its homologs; Region: NTP-PPase_RS21-C6_like; cd11537
1029718002584	homodimer interface [polypeptide binding]; other site
1029718002585	oligomer interface [polypeptide binding]; other site
1029718002586	chemical substrate binding site [chemical binding]; other site
1029718002587	metal binding site [ion binding]; metal-binding site
1029718002588	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1029718002589	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1029718002590	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1029718002591	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1029718002592	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1029718002593	HflX GTPase family; Region: HflX; cd01878
1029718002594	G1 box; other site
1029718002595	GTP/Mg2+ binding site [chemical binding]; other site
1029718002596	Switch I region; other site
1029718002597	G2 box; other site
1029718002598	G3 box; other site
1029718002599	Switch II region; other site
1029718002600	G4 box; other site
1029718002601	G5 box; other site
1029718002602	Transglycosylase; Region: Transgly; pfam00912
1029718002603	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
1029718002604	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1029718002605	Rdx family; Region: Rdx; pfam10262
1029718002606	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1029718002607	active site
1029718002608	metal binding site [ion binding]; metal-binding site
1029718002609	homotetramer interface [polypeptide binding]; other site
1029718002610	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1029718002611	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1029718002612	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1029718002613	homodimer interface [polypeptide binding]; other site
1029718002614	NADP binding site [chemical binding]; other site
1029718002615	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1029718002616	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
1029718002617	active site
1029718002618	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1029718002619	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718002620	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1029718002621	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1029718002622	NodB motif; other site
1029718002623	active site
1029718002624	catalytic site [active]
1029718002625	Zn binding site [ion binding]; other site
1029718002626	hypothetical protein, pseudogene
1029718002627	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1029718002628	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1029718002629	dimerization interface [polypeptide binding]; other site
1029718002630	domain crossover interface; other site
1029718002631	redox-dependent activation switch; other site
1029718002632	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1029718002633	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1029718002634	protein binding site [polypeptide binding]; other site
1029718002635	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1029718002636	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1029718002637	dimer interface [polypeptide binding]; other site
1029718002638	active site
1029718002639	metal binding site [ion binding]; metal-binding site
1029718002640	Protein of unknown function (DUF552); Region: DUF552; pfam04472
1029718002641	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1029718002642	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718002643	RNA binding surface [nucleotide binding]; other site
1029718002644	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1029718002645	active site
1029718002646	DivIVA protein; Region: DivIVA; pfam05103
1029718002647	DivIVA domain; Region: DivI1A_domain; TIGR03544
1029718002648	Methyladenine glycosylase; Region: Adenine_glyco; cl01059
1029718002649	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1029718002650	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718002651	RNA binding surface [nucleotide binding]; other site
1029718002652	Protein of unknown function (DUF552); Region: DUF552; cl00775
1029718002653	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1029718002654	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1029718002655	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
1029718002656	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1029718002657	Mg++ binding site [ion binding]; other site
1029718002658	putative catalytic motif [active]
1029718002659	putative substrate binding site [chemical binding]; other site
1029718002660	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1029718002661	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1029718002662	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718002663	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1029718002664	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1029718002665	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718002666	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1029718002667	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
1029718002668	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1029718002669	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1029718002670	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
1029718002671	PASTA domain of PBP2x-like proteins, second repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_2; cd06575
1029718002672	Cell division protein FtsL; Region: FtsL; cl11433
1029718002673	MraW methylase family; Region: Methyltransf_5; pfam01795
1029718002674	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1029718002675	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1029718002676	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1029718002677	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1029718002678	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1029718002679	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1029718002680	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1029718002681	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1029718002682	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1029718002683	Walker A/P-loop; other site
1029718002684	ATP binding site [chemical binding]; other site
1029718002685	Q-loop/lid; other site
1029718002686	ABC transporter signature motif; other site
1029718002687	Walker B; other site
1029718002688	D-loop; other site
1029718002689	H-loop/switch region; other site
1029718002690	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1029718002691	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1029718002692	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718002693	Walker A/P-loop; other site
1029718002694	ATP binding site [chemical binding]; other site
1029718002695	Q-loop/lid; other site
1029718002696	ABC transporter signature motif; other site
1029718002697	Walker B; other site
1029718002698	D-loop; other site
1029718002699	H-loop/switch region; other site
1029718002700	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1029718002701	catalytic loop [active]
1029718002702	iron binding site [ion binding]; other site
1029718002703	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
1029718002704	4Fe-4S binding domain; Region: Fer4; cl02805
1029718002705	4Fe-4S binding domain; Region: Fer4; pfam00037
1029718002706	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
1029718002707	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
1029718002708	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
1029718002709	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
1029718002710	G1 box; other site
1029718002711	GTP/Mg2+ binding site [chemical binding]; other site
1029718002712	Switch I region; other site
1029718002713	G2 box; other site
1029718002714	Switch II region; other site
1029718002715	G3 box; other site
1029718002716	G4 box; other site
1029718002717	G5 box; other site
1029718002718	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
1029718002719	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002720	FeS/SAM binding site; other site
1029718002721	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1029718002722	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
1029718002723	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002724	FeS/SAM binding site; other site
1029718002725	GTP-binding protein YchF; Reviewed; Region: PRK09601
1029718002726	YchF GTPase; Region: YchF; cd01900
1029718002727	G1 box; other site
1029718002728	GTP/Mg2+ binding site [chemical binding]; other site
1029718002729	Switch I region; other site
1029718002730	G2 box; other site
1029718002731	Switch II region; other site
1029718002732	G3 box; other site
1029718002733	G4 box; other site
1029718002734	G5 box; other site
1029718002735	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1029718002736	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
1029718002737	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1029718002738	NodB motif; other site
1029718002739	active site
1029718002740	catalytic site [active]
1029718002741	Cd binding site [ion binding]; other site
1029718002742	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
1029718002743	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718002744	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1029718002745	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1029718002746	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1029718002747	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1029718002748	TPR motif; other site
1029718002749	Tetratricopeptide repeat; Region: TPR_12; pfam13424
1029718002750	binding surface
1029718002751	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1029718002752	active site
1029718002753	substrate binding site [chemical binding]; other site
1029718002754	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
1029718002755	metal binding site [ion binding]; metal-binding site
1029718002756	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1029718002757	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1029718002758	5S rRNA interface [nucleotide binding]; other site
1029718002759	CTC domain interface [polypeptide binding]; other site
1029718002760	L16 interface [polypeptide binding]; other site
1029718002761	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1029718002762	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1029718002763	homodimer interface [polypeptide binding]; other site
1029718002764	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718002765	catalytic residue [active]
1029718002766	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1029718002767	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
1029718002768	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002769	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002770	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002771	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002772	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1029718002773	nucleotide binding site/active site [active]
1029718002774	HIT family signature motif; other site
1029718002775	catalytic residue [active]
1029718002776	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1029718002777	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1029718002778	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002779	FeS/SAM binding site; other site
1029718002780	TRAM domain; Region: TRAM; cl01282
1029718002781	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1029718002782	RNA methyltransferase, RsmE family; Region: TIGR00046
1029718002783	Ribosomal protein L11 methylase [Translation, ribosomal structure and biogenesis]; Region: PrmA; COG2264
1029718002784	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718002785	S-adenosylmethionine binding site [chemical binding]; other site
1029718002786	HIRAN domain; Region: HIRAN; cl07418
1029718002787	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1029718002788	Dynamin family; Region: Dynamin_N; pfam00350
1029718002789	G1 box; other site
1029718002790	GTP/Mg2+ binding site [chemical binding]; other site
1029718002791	G2 box; other site
1029718002792	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1029718002793	G3 box; other site
1029718002794	Switch II region; other site
1029718002795	GTP/Mg2+ binding site [chemical binding]; other site
1029718002796	G4 box; other site
1029718002797	G5 box; other site
1029718002798	recombination factor protein RarA; Reviewed; Region: PRK13342
1029718002799	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718002800	Walker A motif; other site
1029718002801	ATP binding site [chemical binding]; other site
1029718002802	Walker B motif; other site
1029718002803	arginine finger; other site
1029718002804	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1029718002805	chaperone protein DnaJ; Provisional; Region: PRK14297
1029718002806	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1029718002807	HSP70 interaction site [polypeptide binding]; other site
1029718002808	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1029718002809	substrate binding site [polypeptide binding]; other site
1029718002810	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1029718002811	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1029718002812	dimer interface [polypeptide binding]; other site
1029718002813	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1029718002814	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1029718002815	nucleotide binding site [chemical binding]; other site
1029718002816	NEF interaction site [polypeptide binding]; other site
1029718002817	SBD interface [polypeptide binding]; other site
1029718002818	GrpE; Region: GrpE; pfam01025
1029718002819	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1029718002820	dimer interface [polypeptide binding]; other site
1029718002821	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1029718002822	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
1029718002823	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
1029718002824	DNA-binding site [nucleotide binding]; DNA binding site
1029718002825	coproporphyrinogen III oxidase; Provisional; Region: PRK05799
1029718002826	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1029718002827	FeS/SAM binding site; other site
1029718002828	HemN C-terminal domain; Region: HemN_C; pfam06969
1029718002829	GTP-binding protein LepA; Provisional; Region: PRK05433
1029718002830	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1029718002831	G1 box; other site
1029718002832	putative GEF interaction site [polypeptide binding]; other site
1029718002833	GTP/Mg2+ binding site [chemical binding]; other site
1029718002834	Switch I region; other site
1029718002835	G2 box; other site
1029718002836	G3 box; other site
1029718002837	Switch II region; other site
1029718002838	G4 box; other site
1029718002839	G5 box; other site
1029718002840	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1029718002841	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1029718002842	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1029718002843	Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454
1029718002844	stage II sporulation protein P; Region: spore_II_P; TIGR02867
1029718002845	germination protease; Provisional; Region: PRK12362
1029718002846	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1029718002847	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1029718002848	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1029718002849	Competence protein; Region: Competence; pfam03772
1029718002850	SpoVA protein; Region: SpoVA; cl04298
1029718002851	stage V sporulation protein AD; Validated; Region: PRK08304
1029718002852	stage V sporulation protein AD; Provisional; Region: PRK12404
1029718002853	SpoVA protein; Region: SpoVA; cl04298
1029718002854	Flagellar protein (FlbD); Region: FlbD; pfam06289
1029718002855	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1029718002856	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1029718002857	flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497
1029718002858	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1029718002859	Walker A motif/ATP binding site; other site
1029718002860	Walker B motif; other site
1029718002861	flagellar assembly protein FliH; Region: FliH_bacil; TIGR03825
1029718002862	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1029718002863	FliG C-terminal domain; Region: FliG_C; pfam01706
1029718002864	flagellar basal body rod protein FlgC; Provisional; Region: flgC; PRK12630
1029718002865	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1029718002866	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1029718002867	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
1029718002868	flagellin; Provisional; Region: PRK12807
1029718002869	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1029718002870	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1029718002871	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1029718002872	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1029718002873	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1029718002874	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
1029718002875	methionine cluster; other site
1029718002876	active site
1029718002877	phosphorylation site [posttranslational modification]
1029718002878	metal binding site [ion binding]; metal-binding site
1029718002879	Asp23 family; Region: Asp23; pfam03780
1029718002880	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
1029718002881	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
1029718002882	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; pfam09581
1029718002883	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; cl09771
1029718002884	stage III sporulation protein AD; Region: spore_III_AD; TIGR02849
1029718002885	stage III sporulation protein AC; Region: spore_III_AC; TIGR02848
1029718002886	Stage III sporulation protein AB (spore_III_AB); Region: Spore_III_AB; cl08022
1029718002887	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
1029718002888	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1029718002889	Walker A motif; other site
1029718002890	ATP binding site [chemical binding]; other site
1029718002891	elongation factor P; Validated; Region: PRK00529
1029718002892	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1029718002893	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1029718002894	RNA binding site [nucleotide binding]; other site
1029718002895	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1029718002896	RNA binding site [nucleotide binding]; other site
1029718002897	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1029718002898	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1029718002899	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1029718002900	Type II/IV secretion system protein; Region: T2SE; pfam00437
1029718002901	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1029718002902	Walker A motif; other site
1029718002903	ATP binding site [chemical binding]; other site
1029718002904	Walker B motif; other site
1029718002905	Predicted RNA-binding protein homologous to eukaryotic snRNP [Transcription]; Region: COG1293
1029718002906	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1029718002907	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1029718002908	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1029718002909	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1029718002910	Walker A/P-loop; other site
1029718002911	ATP binding site [chemical binding]; other site
1029718002912	Q-loop/lid; other site
1029718002913	ABC transporter signature motif; other site
1029718002914	Walker B; other site
1029718002915	D-loop; other site
1029718002916	H-loop/switch region; other site
1029718002917	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1029718002918	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718002919	ABC-ATPase subunit  interface; other site
1029718002920	dimer interface [polypeptide binding]; other site
1029718002921	putative PBP binding regions; other site
1029718002922	heme ABC transporter, heme-binding protein isdE; Region: IsdE; TIGR03659
1029718002923	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1029718002924	intersubunit interface [polypeptide binding]; other site
1029718002925	peroxiredoxin; Region: AhpC; TIGR03137
1029718002926	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1029718002927	dimer interface [polypeptide binding]; other site
1029718002928	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1029718002929	catalytic triad [active]
1029718002930	peroxidatic and resolving cysteines [active]
1029718002931	Predicted membrane protein [Function unknown]; Region: COG2510
1029718002932	Predicted membrane protein [Function unknown]; Region: COG2510
1029718002933	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
1029718002934	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
1029718002935	beta-galactosidase; Region: BGL; TIGR03356
1029718002936	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1029718002937	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1029718002938	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
1029718002939	active site
1029718002940	P-loop; other site
1029718002941	phosphorylation site [posttranslational modification]
1029718002942	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
1029718002943	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
1029718002944	NAD binding site [chemical binding]; other site
1029718002945	sugar binding site [chemical binding]; other site
1029718002946	divalent metal binding site [ion binding]; other site
1029718002947	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1029718002948	dimer interface [polypeptide binding]; other site
1029718002949	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
1029718002950	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1029718002951	AP (apurinic/apyrimidinic) site pocket; other site
1029718002952	DNA interaction; other site
1029718002953	Metal-binding active site; metal-binding site
1029718002954	L-ribulose-5-phosphate 4-epimerase, truncated by premature stop codon, pseudogene
1029718002955	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
1029718002956	active site
1029718002957	P-loop; other site
1029718002958	phosphorylation site [posttranslational modification]
1029718002959	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
1029718002960	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
1029718002961	active site
1029718002962	phosphorylation site [posttranslational modification]
1029718002963	L-ascorbate 6-phosphate lactonase, pseudogene
1029718002964	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
1029718002965	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
1029718002966	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
1029718002967	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
1029718002968	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
1029718002969	heme-binding site [chemical binding]; other site
1029718002970	superfamily containing globins and truncated hemoglobins; Region: globin_like; cl00280
1029718002971	heme-binding site [chemical binding]; other site
1029718002972	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1029718002973	cellobiose phosphotransferase system IIC component; Reviewed; Region: celD; PRK09592
1029718002974	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
1029718002975	Linear amide C-N hydrolases, choloylglycine hydrolase family; Region: CBAH; pfam02275
1029718002976	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1029718002977	active site
1029718002978	SCP-2 sterol transfer family; Region: SCP2; pfam02036
1029718002979	Sodium:dicarboxylate symporter family; Region: SDF; cl00573
1029718002980	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1029718002981	sporulation sigma factor SigF; Validated; Region: PRK05572
1029718002982	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718002983	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718002984	DNA binding residues [nucleotide binding]
1029718002985	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1029718002986	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718002987	ATP binding site [chemical binding]; other site
1029718002988	Mg2+ binding site [ion binding]; other site
1029718002989	G-X-G motif; other site
1029718002990	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1029718002991	anti sigma factor interaction site; other site
1029718002992	regulatory phosphorylation site [posttranslational modification]; other site
1029718002993	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1029718002994	Peptidase family M28; Region: Peptidase_M28; pfam04389
1029718002995	metal binding site [ion binding]; metal-binding site
1029718002996	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1029718002997	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1029718002998	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718002999	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1029718003000	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003001	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003002	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003003	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1029718003004	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
1029718003005	putative active site [active]
1029718003006	putative metal binding site [ion binding]; other site
1029718003007	Ca2+/Na+ antiporter [Inorganic ion transport and metabolism]; Region: ECM27; COG0530
1029718003008	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
1029718003009	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1029718003010	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1029718003011	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718003012	homodimer interface [polypeptide binding]; other site
1029718003013	catalytic residue [active]
1029718003014	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1029718003015	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1029718003016	dimer interface [polypeptide binding]; other site
1029718003017	putative CheW interface [polypeptide binding]; other site
1029718003018	DNA repair protein RadA; Provisional; Region: PRK11823
1029718003019	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1029718003020	Walker A motif; other site
1029718003021	ATP binding site [chemical binding]; other site
1029718003022	Walker B motif; other site
1029718003023	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1029718003024	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
1029718003025	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
1029718003026	active site
1029718003027	catalytic triad [active]
1029718003028	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
1029718003029	active site
1029718003030	catalytic triad [active]
1029718003031	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1029718003032	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1029718003033	glutaminase active site [active]
1029718003034	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1029718003035	dimer interface [polypeptide binding]; other site
1029718003036	active site
1029718003037	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1029718003038	dimer interface [polypeptide binding]; other site
1029718003039	active site
1029718003040	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003041	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003042	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003043	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003044	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
1029718003045	Putative D-isomer specific 2-hydroxyacid dehydrogenases; Region: 2-Hacid_dh_4; cd12162
1029718003046	putative ligand binding site [chemical binding]; other site
1029718003047	putative NAD binding site [chemical binding]; other site
1029718003048	catalytic site [active]
1029718003049	Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis [Secondary metabolites biosynthesis, transport, and catabolism]; Region: FrnE; COG2761
1029718003050	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1029718003051	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1029718003052	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1029718003053	putative active site [active]
1029718003054	aminotransferase A; Validated; Region: PRK07683
1029718003055	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1029718003056	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1029718003057	homodimer interface [polypeptide binding]; other site
1029718003058	catalytic residue [active]
1029718003059	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; Region: CobA_CobO_BtuR; pfam02572
1029718003060	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
1029718003061	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
1029718003062	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
1029718003063	trimer interface [polypeptide binding]; other site
1029718003064	active site
1029718003065	substrate binding site [chemical binding]; other site
1029718003066	CoA binding site [chemical binding]; other site
1029718003067	single-stranded DNA-binding protein; Provisional; Region: PRK05813
1029718003068	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1029718003069	dimer interface [polypeptide binding]; other site
1029718003070	ssDNA binding site [nucleotide binding]; other site
1029718003071	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1029718003072	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1029718003073	Domain of unknown function (DUF4364); Region: DUF4364; pfam14277
1029718003074	Predicted transcriptional regulator [Transcription]; Region: COG3432
1029718003075	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
1029718003076	Beta-lactamase enzyme family; Region: Beta-lactamase2; pfam13354
1029718003077	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1029718003078	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1029718003079	active site
1029718003080	HIGH motif; other site
1029718003081	nucleotide binding site [chemical binding]; other site
1029718003082	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1029718003083	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1029718003084	active site
1029718003085	KMSKS motif; other site
1029718003086	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1029718003087	tRNA binding surface [nucleotide binding]; other site
1029718003088	anticodon binding site; other site
1029718003089	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1029718003090	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1029718003091	TPR motif; other site
1029718003092	TPR repeat; Region: TPR_11; pfam13414
1029718003093	binding surface
1029718003094	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1029718003095	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1029718003096	RecX family; Region: RecX; cl00936
1029718003097	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1029718003098	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1029718003099	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1029718003100	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003101	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1029718003102	Rubredoxin; Region: Rubredoxin; pfam00301
1029718003103	iron binding site [ion binding]; other site
1029718003104	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
1029718003105	Rubrerythrin [Energy production and conversion]; Region: COG1592
1029718003106	diiron binding motif [ion binding]; other site
1029718003107	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003108	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
1029718003109	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1029718003110	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1029718003111	nucleotide binding pocket [chemical binding]; other site
1029718003112	K-X-D-G motif; other site
1029718003113	catalytic site [active]
1029718003114	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1029718003115	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
1029718003116	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1029718003117	Dimer interface [polypeptide binding]; other site
1029718003118	BRCT sequence motif; other site
1029718003119	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
1029718003120	Part of AAA domain; Region: AAA_19; pfam13245
1029718003121	Family description; Region: UvrD_C_2; pfam13538
1029718003122	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1029718003123	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718003124	RNA binding surface [nucleotide binding]; other site
1029718003125	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1029718003126	active site
1029718003127	uracil binding [chemical binding]; other site
1029718003128	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1029718003129	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1029718003130	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1029718003131	catalytic residue [active]
1029718003132	triple tyrosine motif-containing protein; Provisional; Region: PRK14081
1029718003133	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1029718003134	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1029718003135	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
1029718003136	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1029718003137	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1029718003138	active site
1029718003139	dimer interface [polypeptide binding]; other site
1029718003140	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1029718003141	dimer interface [polypeptide binding]; other site
1029718003142	active site
1029718003143	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1029718003144	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4152
1029718003145	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718003146	Walker A/P-loop; other site
1029718003147	ATP binding site [chemical binding]; other site
1029718003148	Q-loop/lid; other site
1029718003149	ABC transporter signature motif; other site
1029718003150	Walker B; other site
1029718003151	D-loop; other site
1029718003152	H-loop/switch region; other site
1029718003153	Domain of unknown function (DUF4162); Region: DUF4162; pfam13732
1029718003154	DJ-1 family protein; Region: not_thiJ; TIGR01383
1029718003155	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1029718003156	conserved cys residue [active]
1029718003157	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
1029718003158	trimer interface [polypeptide binding]; other site
1029718003159	active site
1029718003160	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1029718003161	amidase catalytic site [active]
1029718003162	Zn binding residues [ion binding]; other site
1029718003163	substrate binding site [chemical binding]; other site
1029718003164	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1029718003165	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1029718003166	hypothetical protein, pseudogene
1029718003167	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1029718003168	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1029718003169	Walker A/P-loop; other site
1029718003170	ATP binding site [chemical binding]; other site
1029718003171	Q-loop/lid; other site
1029718003172	ABC transporter signature motif; other site
1029718003173	Walker B; other site
1029718003174	D-loop; other site
1029718003175	H-loop/switch region; other site
1029718003176	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718003177	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718003178	ATP binding site [chemical binding]; other site
1029718003179	Mg2+ binding site [ion binding]; other site
1029718003180	G-X-G motif; other site
1029718003181	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718003182	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718003183	active site
1029718003184	phosphorylation site [posttranslational modification]
1029718003185	intermolecular recognition site; other site
1029718003186	dimerization interface [polypeptide binding]; other site
1029718003187	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718003188	DNA binding site [nucleotide binding]
1029718003189	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1029718003190	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12817
1029718003191	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1029718003192	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1029718003193	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12818
1029718003194	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1029718003195	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1029718003196	RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479
1029718003197	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718003198	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1029718003199	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1029718003200	DNA binding residues [nucleotide binding]
1029718003201	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
1029718003202	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1029718003203	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1029718003204	FHIPEP family; Region: FHIPEP; pfam00771
1029718003205	bifunctional flagellar biosynthesis protein FliR/FlhB; Provisional; Region: PRK12772
1029718003206	Bacterial export proteins, family 1; Region: Bac_export_1; cl00734
1029718003207	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1029718003208	Bacterial export proteins, family 3; Region: Bac_export_3; cl00867
1029718003209	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1029718003210	Flagellar biosynthesis protein, FliO; Region: FliO; cl01247
1029718003211	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
1029718003212	flagellar motor protein MotS; Reviewed; Region: PRK06925
1029718003213	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1029718003214	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1029718003215	ligand binding site [chemical binding]; other site
1029718003216	flagellar motor protein MotP; Reviewed; Region: PRK06926
1029718003217	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1029718003218	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1029718003219	active site
1029718003220	adenylosuccinate lyase; Provisional; Region: PRK07492
1029718003221	Adenylsuccinate lyase (ASL)_subgroup 1; Region: Adenylsuccinate_lyase_1; cd01360
1029718003222	tetramer interface [polypeptide binding]; other site
1029718003223	active site
1029718003224	Adenylosuccinate lyase C-terminus; Region: ADSL_C; smart00998
1029718003225	putative oxidoreductase; Provisional; Region: PRK11579
1029718003226	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
1029718003227	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
1029718003228	Adenylosuccinate synthetase; Region: Adenylsucc_synt; smart00788
1029718003229	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
1029718003230	GDP-binding site [chemical binding]; other site
1029718003231	ACT binding site; other site
1029718003232	IMP binding site; other site
1029718003233	Glutaredoxin-related protein [Posttranslational modification, protein turnover, chaperones]; Region: COG4545
1029718003234	segregation and condensation protein B; Reviewed; Region: scpB; PRK00135
1029718003235	ScpA/B protein; Region: ScpA_ScpB; cl00598
1029718003236	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718003237	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
1029718003238	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1029718003239	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1029718003240	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1029718003241	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1029718003242	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
1029718003243	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1029718003244	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1029718003245	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1029718003246	phosphopentomutase; Provisional; Region: PRK05362
1029718003247	Metalloenzyme superfamily; Region: Metalloenzyme; pfam01676
1029718003248	Integral membrane protein DUF95; Region: DUF95; cl00572
1029718003249	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1029718003250	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1029718003251	dimer interface [polypeptide binding]; other site
1029718003252	ADP-ribose binding site [chemical binding]; other site
1029718003253	active site
1029718003254	nudix motif; other site
1029718003255	metal binding site [ion binding]; metal-binding site
1029718003256	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1029718003257	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1029718003258	Walker A/P-loop; other site
1029718003259	ATP binding site [chemical binding]; other site
1029718003260	Q-loop/lid; other site
1029718003261	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1029718003262	ABC transporter signature motif; other site
1029718003263	Walker B; other site
1029718003264	D-loop; other site
1029718003265	H-loop/switch region; other site
1029718003266	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1029718003267	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1029718003268	active site
1029718003269	metal binding site [ion binding]; metal-binding site
1029718003270	DNA binding site [nucleotide binding]
1029718003271	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1029718003272	competence damage-inducible protein A; Provisional; Region: PRK00549
1029718003273	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1029718003274	putative MPT binding site; other site
1029718003275	Uncharacterized protein (competence- and mitomycin-induced) [General function prediction only]; Region: CinA; COG1546
1029718003276	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718003277	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1029718003278	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718003279	dimer interface [polypeptide binding]; other site
1029718003280	phosphorylation site [posttranslational modification]
1029718003281	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718003282	ATP binding site [chemical binding]; other site
1029718003283	Mg2+ binding site [ion binding]; other site
1029718003284	G-X-G motif; other site
1029718003285	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718003286	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718003287	active site
1029718003288	phosphorylation site [posttranslational modification]
1029718003289	intermolecular recognition site; other site
1029718003290	dimerization interface [polypeptide binding]; other site
1029718003291	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718003292	DNA binding site [nucleotide binding]
1029718003293	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1029718003294	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5368
1029718003295	Putative glucoamylase; Region: Glycoamylase; pfam10091
1029718003296	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1029718003297	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1029718003298	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1029718003299	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1029718003300	Walker A/P-loop; other site
1029718003301	ATP binding site [chemical binding]; other site
1029718003302	Q-loop/lid; other site
1029718003303	ABC transporter signature motif; other site
1029718003304	Walker B; other site
1029718003305	D-loop; other site
1029718003306	H-loop/switch region; other site
1029718003307	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1029718003308	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
1029718003309	putative ligand binding residues [chemical binding]; other site
1029718003310	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1029718003311	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1029718003312	Walker A/P-loop; other site
1029718003313	ATP binding site [chemical binding]; other site
1029718003314	Q-loop/lid; other site
1029718003315	ABC transporter signature motif; other site
1029718003316	Walker B; other site
1029718003317	D-loop; other site
1029718003318	H-loop/switch region; other site
1029718003319	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718003320	ABC-ATPase subunit  interface; other site
1029718003321	dimer interface [polypeptide binding]; other site
1029718003322	putative PBP binding regions; other site
1029718003323	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1029718003324	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718003325	ABC-ATPase subunit  interface; other site
1029718003326	dimer interface [polypeptide binding]; other site
1029718003327	putative PBP binding regions; other site
1029718003328	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1029718003329	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1029718003330	intersubunit interface [polypeptide binding]; other site
1029718003331	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1029718003332	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718003333	ABC-ATPase subunit  interface; other site
1029718003334	dimer interface [polypeptide binding]; other site
1029718003335	putative PBP binding regions; other site
1029718003336	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1029718003337	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1029718003338	ABC-ATPase subunit  interface; other site
1029718003339	dimer interface [polypeptide binding]; other site
1029718003340	putative PBP binding regions; other site
1029718003341	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1029718003342	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1029718003343	Walker A/P-loop; other site
1029718003344	ATP binding site [chemical binding]; other site
1029718003345	Q-loop/lid; other site
1029718003346	ABC transporter signature motif; other site
1029718003347	Walker B; other site
1029718003348	D-loop; other site
1029718003349	H-loop/switch region; other site
1029718003350	H+ Antiporter protein; Region: 2A0121; TIGR00900
1029718003351	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1029718003352	Uncharacterized member of the PurR regulon [General function prediction only]; Region: yhhQ; COG1738
1029718003353	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1244
1029718003354	Protein of unknown function DUF262; Region: DUF262; pfam03235
1029718003355	Uncharacterized conserved protein [Function unknown]; Region: COG1479
1029718003356	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
1029718003357	Cupin domain; Region: Cupin_2; cl17218
1029718003358	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1029718003359	active site
1029718003360	conformational flexibility of ligand binding pocket; other site
1029718003361	ADP-ribosylating toxin turn-turn motif; other site
1029718003362	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
1029718003363	dimanganese center [ion binding]; other site
1029718003364	Flavin reductase like domain; Region: Flavin_Reduct; pfam01613
1029718003365	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
1029718003366	Rubredoxin [Energy production and conversion]; Region: COG1773
1029718003367	iron binding site [ion binding]; other site
1029718003368	Rubrerythrin [Energy production and conversion]; Region: COG1592
1029718003369	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1029718003370	binuclear metal center [ion binding]; other site
1029718003371	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1029718003372	iron binding site [ion binding]; other site
1029718003373	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1029718003374	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1029718003375	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1029718003376	MarR family; Region: MarR_2; pfam12802
1029718003377	Catalase [Inorganic ion transport and metabolism]; Region: KatE; COG0753
1029718003378	Clade 3 of the heme-binding enzyme catalase; Region: catalase_clade_3; cd08156
1029718003379	tetramer interface [polypeptide binding]; other site
1029718003380	heme binding pocket [chemical binding]; other site
1029718003381	NADPH binding site [chemical binding]; other site
1029718003382	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1029718003383	metal binding site 2 [ion binding]; metal-binding site
1029718003384	putative DNA binding helix; other site
1029718003385	metal binding site 1 [ion binding]; metal-binding site
1029718003386	dimer interface [polypeptide binding]; other site
1029718003387	structural Zn2+ binding site [ion binding]; other site
1029718003388	BioY family; Region: BioY; pfam02632
1029718003389	Domain of unknown function (DUF4180); Region: DUF4180; pfam13788
1029718003390	hypothetical protein, pseudogene
1029718003391	Methyladenine glycosylase; Region: Adenine_glyco; pfam03352
1029718003392	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1029718003393	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1029718003394	prophage SFBMP4, partial
1029718003395	CAAX protease self-immunity; Region: Abi; pfam02517
1029718003396	virulence-associated protein E, N-ter only, pseudogene
1029718003397	Prophage antirepressor [Transcription]; Region: COG3617
1029718003398	BRO family, N-terminal domain; Region: Bro-N; smart01040
1029718003399	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
1029718003400	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1029718003401	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1029718003402	AAA domain; Region: AAA_30; pfam13604
1029718003403	Family description; Region: UvrD_C_2; pfam13538
1029718003404	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1029718003405	non-specific DNA binding site [nucleotide binding]; other site
1029718003406	salt bridge; other site
1029718003407	sequence-specific DNA binding site [nucleotide binding]; other site
1029718003408	Catalytic domain of type II restriction endonucleases BfiI and NgoFVII, and uncharacterized proteins with a DEAD domain; Region: PLDc_Bfil_DEXD_like; cd09117
1029718003409	homodimer interface [polypeptide binding]; other site
1029718003410	putative active site [active]
1029718003411	catalytic site [active]
1029718003412	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1029718003413	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1029718003414	cofactor binding site; other site
1029718003415	DNA binding site [nucleotide binding]
1029718003416	substrate interaction site [chemical binding]; other site
1029718003417	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1029718003418	Site-specific DNA methylase [DNA replication, recombination, and repair]; Region: Dcm; COG0270
1029718003419	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1029718003420	cofactor binding site; other site
1029718003421	DNA binding site [nucleotide binding]
1029718003422	substrate interaction site [chemical binding]; other site
1029718003423	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1029718003424	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
1029718003425	non-specific DNA binding site [nucleotide binding]; other site
1029718003426	salt bridge; other site
1029718003427	sequence-specific DNA binding site [nucleotide binding]; other site
1029718003428	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1029718003429	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718003430	S-adenosylmethionine binding site [chemical binding]; other site
1029718003431	Dehydroquinate synthase-like (DHQ-like) and iron-containing alcohol dehydrogenases (Fe-ADH); Region: DHQ_Fe-ADH; cl02872
1029718003432	active site
1029718003433	NAD binding site [chemical binding]; other site
1029718003434	pyrophosphatase PpaX; Provisional; Region: PRK13288
1029718003435	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718003436	active site
1029718003437	motif I; other site
1029718003438	motif II; other site
1029718003439	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1029718003440	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1029718003441	dimer interface [polypeptide binding]; other site
1029718003442	putative CheW interface [polypeptide binding]; other site
1029718003443	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1029718003444	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1029718003445	dimer interface [polypeptide binding]; other site
1029718003446	putative CheW interface [polypeptide binding]; other site
1029718003447	Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit [Energy production and conversion]; Region: OadB; COG1883
1029718003448	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06549
1029718003449	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1029718003450	carboxyltransferase (CT) interaction site; other site
1029718003451	biotinylation site [posttranslational modification]; other site
1029718003452	oxaloacetate decarboxylase; Provisional; Region: PRK12331
1029718003453	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1029718003454	active site
1029718003455	catalytic residues [active]
1029718003456	metal binding site [ion binding]; metal-binding site
1029718003457	homodimer binding site [polypeptide binding]; other site
1029718003458	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1029718003459	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1029718003460	trimerization site [polypeptide binding]; other site
1029718003461	active site
1029718003462	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1029718003463	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1029718003464	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1029718003465	catalytic residue [active]
1029718003466	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1029718003467	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
1029718003468	FeS assembly protein SufB; Region: sufB; TIGR01980
1029718003469	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814; cl03223
1029718003470	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
1029718003471	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
1029718003472	Walker A/P-loop; other site
1029718003473	ATP binding site [chemical binding]; other site
1029718003474	Q-loop/lid; other site
1029718003475	ABC transporter signature motif; other site
1029718003476	Walker B; other site
1029718003477	D-loop; other site
1029718003478	H-loop/switch region; other site
1029718003479	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718003480	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1029718003481	active site
1029718003482	motif I; other site
1029718003483	motif II; other site
1029718003484	haloacid dehalogenase-like hydrolase; Region: HAD; cl17202
1029718003485	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1029718003486	active site
1029718003487	dimer interface [polypeptide binding]; other site
1029718003488	metal binding site [ion binding]; metal-binding site
1029718003489	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1029718003490	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1029718003491	Tetramer interface [polypeptide binding]; other site
1029718003492	active site
1029718003493	FMN-binding site [chemical binding]; other site
1029718003494	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1029718003495	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1029718003496	active site
1029718003497	hinge; other site
1029718003498	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1029718003499	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1029718003500	vitamin B12-dependent ribonucleotide reductase; Validated; Region: PRK06556
1029718003501	Class II vitamin B12-dependent ribonucleotide reductase; Region: Ribonuc_red_2_N; pfam08471
1029718003502	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
1029718003503	active site
1029718003504	dimer interface [polypeptide binding]; other site
1029718003505	effector binding site; other site
1029718003506	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1029718003507	TSCPD domain; Region: TSCPD; cl14834
1029718003508	RNA polymerase beta'' subunit; Reviewed; Region: rpoC2; CHL00117
1029718003509	AsnC-type helix-turn-helix domain; Region: HTH_AsnC-type; pfam13404
1029718003510	AsnC family; Region: AsnC_trans_reg; pfam01037
1029718003511	Domain of unknown function (DUF378); Region: DUF378; cl00943
1029718003512	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_HprK; cl00270
1029718003513	active site
1029718003514	metal-binding site [ion binding]
1029718003515	nucleotide-binding site [chemical binding]; other site
1029718003516	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1029718003517	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1029718003518	putative acyl-acceptor binding pocket; other site
1029718003519	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
1029718003520	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1029718003521	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1029718003522	active site
1029718003523	HIGH motif; other site
1029718003524	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1029718003525	active site
1029718003526	KMSKS motif; other site
1029718003527	RNase_H superfamily; Region: RNase_H_2; pfam13482
1029718003528	FeoA domain; Region: FeoA; cl00838
1029718003529	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1029718003530	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1029718003531	G1 box; other site
1029718003532	GTP/Mg2+ binding site [chemical binding]; other site
1029718003533	Switch I region; other site
1029718003534	G2 box; other site
1029718003535	G3 box; other site
1029718003536	Switch II region; other site
1029718003537	G4 box; other site
1029718003538	G5 box; other site
1029718003539	Nucleoside recognition; Region: Gate; pfam07670
1029718003540	Nucleoside recognition; Region: Gate; pfam07670
1029718003541	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1029718003542	Putative carbohydrate binding domain; Region: CBM_X; pfam06204
1029718003543	Glycoside hydrolase family 94 N-terminal-like domain of uncharacterized function; Region: GH94N_like_4; cd11751
1029718003544	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1029718003545	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1029718003546	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
1029718003547	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
1029718003548	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1029718003549	active site
1029718003550	HIGH motif; other site
1029718003551	KMSK motif region; other site
1029718003552	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1029718003553	tRNA binding surface [nucleotide binding]; other site
1029718003554	anticodon binding site; other site
1029718003555	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718003556	S-adenosylmethionine binding site [chemical binding]; other site
1029718003557	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1029718003558	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
1029718003559	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1029718003560	Uncharacterized conserved protein [Function unknown]; Region: COG1543
1029718003561	Arginase family; Region: Arginase; cd09989
1029718003562	active site
1029718003563	Mn binding site [ion binding]; other site
1029718003564	oligomer interface [polypeptide binding]; other site
1029718003565	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1029718003566	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
1029718003567	active site
1029718003568	catalytic site [active]
1029718003569	substrate binding site [chemical binding]; other site
1029718003570	glutamate dehydrogenase; Provisional; Region: PRK09414
1029718003571	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1029718003572	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1029718003573	NAD(P) binding pocket [chemical binding]; other site
1029718003574	Domain of unknown function (DUF4358); Region: DUF4358; pfam14270
1029718003575	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1029718003576	phosphofructokinase; Region: PFK_mixed; TIGR02483
1029718003577	active site
1029718003578	ADP/pyrophosphate binding site [chemical binding]; other site
1029718003579	dimerization interface [polypeptide binding]; other site
1029718003580	allosteric effector site; other site
1029718003581	fructose-1,6-bisphosphate binding site; other site
1029718003582	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1029718003583	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1029718003584	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718003585	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
1029718003586	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1029718003587	catalytic triad [active]
1029718003588	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1029718003589	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
1029718003590	active site
1029718003591	Domain of unknown function (DUF4214); Region: DUF4214; pfam13946
1029718003592	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
1029718003593	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
1029718003594	NAD binding site [chemical binding]; other site
1029718003595	substrate binding site [chemical binding]; other site
1029718003596	homodimer interface [polypeptide binding]; other site
1029718003597	active site
1029718003598	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1029718003599	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1029718003600	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1029718003601	active site
1029718003602	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1029718003603	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
1029718003604	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
1029718003605	Na binding site [ion binding]; other site
1029718003606	putative substrate binding site [chemical binding]; other site
1029718003607	cytosine deaminase; Provisional; Region: PRK09230
1029718003608	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1029718003609	active site
1029718003610	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1029718003611	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1029718003612	putative metal binding site; other site
1029718003613	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
1029718003614	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1029718003615	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1029718003616	AAA domain; Region: AAA_27; pfam13514
1029718003617	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1029718003618	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1029718003619	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1029718003620	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1029718003621	NodB motif; other site
1029718003622	active site
1029718003623	catalytic site [active]
1029718003624	Zn binding site [ion binding]; other site
1029718003625	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1029718003626	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1029718003627	Glycoprotease family; Region: Peptidase_M22; pfam00814
1029718003628	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1029718003629	Predicted membrane protein [Function unknown]; Region: COG3601
1029718003630	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1029718003631	RNA-binding protein, pseudogene
1029718003632	peptide chain release factor 2; Provisional; Region: PRK05589
1029718003633	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1029718003634	RF-1 domain; Region: RF-1; pfam00472
1029718003635	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1029718003636	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1029718003637	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1029718003638	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718003639	nucleotide binding region [chemical binding]; other site
1029718003640	ATP-binding site [chemical binding]; other site
1029718003641	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1029718003642	30S subunit binding site; other site
1029718003643	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1029718003644	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718003645	active site
1029718003646	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1029718003647	AAA domain; Region: AAA_30; pfam13604
1029718003648	Family description; Region: UvrD_C_2; pfam13538
1029718003649	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
1029718003650	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
1029718003651	active site
1029718003652	dimer interface [polypeptide binding]; other site
1029718003653	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1029718003654	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1029718003655	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1029718003656	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1029718003657	Stage III sporulation protein D; Region: SpoIIID; pfam12116
1029718003658	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1029718003659	Peptidase family M23; Region: Peptidase_M23; pfam01551
1029718003660	Stage II sporulation protein; Region: SpoIID; pfam08486
1029718003661	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1029718003662	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1029718003663	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1029718003664	hinge; other site
1029718003665	active site
1029718003666	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1029718003667	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1029718003668	active site
1029718003669	homodimer interface [polypeptide binding]; other site
1029718003670	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1029718003671	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1029718003672	Mg++ binding site [ion binding]; other site
1029718003673	putative catalytic motif [active]
1029718003674	substrate binding site [chemical binding]; other site
1029718003675	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718003676	active site
1029718003677	Low molecular weight phosphatase family; Region: LMWPc; cl00105
1029718003678	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1029718003679	active site
1029718003680	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1029718003681	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1029718003682	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1029718003683	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1029718003684	RF-1 domain; Region: RF-1; pfam00472
1029718003685	Protein of unknown function (DUF1385); Region: DUF1385; cl01595
1029718003686	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1029718003687	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1029718003688	S-adenosylmethionine binding site [chemical binding]; other site
1029718003689	thymidine kinase; Provisional; Region: PRK04296
1029718003690	AAA domain; Region: AAA_14; pfam13173
1029718003691	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1029718003692	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1029718003693	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1029718003694	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1029718003695	RNA binding site [nucleotide binding]; other site
1029718003696	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1029718003697	Walker A motif; other site
1029718003698	ATP binding site [chemical binding]; other site
1029718003699	Walker B motif; other site
1029718003700	CTP synthetase; Validated; Region: pyrG; PRK05380
1029718003701	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
1029718003702	Catalytic site [active]
1029718003703	active site
1029718003704	UTP binding site [chemical binding]; other site
1029718003705	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
1029718003706	active site
1029718003707	putative oxyanion hole; other site
1029718003708	catalytic triad [active]
1029718003709	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
1029718003710	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
1029718003711	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; cl09775
1029718003712	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1029718003713	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1029718003714	Spore germination protein; Region: Spore_permease; cl17796
1029718003715	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1029718003716	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1029718003717	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1029718003718	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1029718003719	cyanophycin synthetase; Provisional; Region: PRK14016
1029718003720	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1029718003721	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718003722	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1029718003723	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
1029718003724	proposed catalytic triad [active]
1029718003725	active site nucleophile [active]
1029718003726	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1029718003727	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1029718003728	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1029718003729	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1029718003730	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1029718003731	YabG peptidase U57; Region: Peptidase_U57; cl05250
1029718003732	enoyl-(acyl carrier protein) reductase; Provisional; Region: PRK08594
1029718003733	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
1029718003734	NAD binding site [chemical binding]; other site
1029718003735	homotetramer interface [polypeptide binding]; other site
1029718003736	homodimer interface [polypeptide binding]; other site
1029718003737	substrate binding site [chemical binding]; other site
1029718003738	active site
1029718003739	spore coat protein, CotS family; Region: spore_CotS; TIGR02906
1029718003740	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1029718003741	substrate binding site [chemical binding]; other site
1029718003742	This family is most closely related to the GT1 family of glycosyltransferases. mtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the...; Region: GT1_mtfB_like; cd03809
1029718003743	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1029718003744	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1029718003745	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1029718003746	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1029718003747	EDD domain protein, DegV family; Region: DegV; TIGR00762
1029718003748	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1029718003749	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1029718003750	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
1029718003751	VanW like protein; Region: VanW; pfam04294
1029718003752	G5 domain; Region: G5; pfam07501
1029718003753	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
1029718003754	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1029718003755	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1029718003756	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1029718003757	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1029718003758	minor groove reading motif; other site
1029718003759	helix-hairpin-helix signature motif; other site
1029718003760	substrate binding pocket [chemical binding]; other site
1029718003761	active site
1029718003762	Iron-sulfur binding domain of endonuclease III; Region: EndIII_4Fe-2S; cl15304
1029718003763	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1029718003764	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1029718003765	putative acyl-acceptor binding pocket; other site
1029718003766	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1029718003767	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1029718003768	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1029718003769	MgtE intracellular N domain; Region: MgtE_N; pfam03448
1029718003770	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1029718003771	Predicted membrane protein [Function unknown]; Region: COG2323
1029718003772	Domain of unknown function (DUF4363); Region: DUF4363; pfam14276
1029718003773	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1029718003774	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1029718003775	intersubunit interface [polypeptide binding]; other site
1029718003776	active site
1029718003777	zinc binding site [ion binding]; other site
1029718003778	Na+ binding site [ion binding]; other site
1029718003779	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
1029718003780	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
1029718003781	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1029718003782	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1029718003783	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1029718003784	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1029718003785	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1029718003786	G1 box; other site
1029718003787	GTP/Mg2+ binding site [chemical binding]; other site
1029718003788	Switch I region; other site
1029718003789	G2 box; other site
1029718003790	G3 box; other site
1029718003791	Switch II region; other site
1029718003792	G4 box; other site
1029718003793	G5 box; other site
1029718003794	Nucleoside recognition; Region: Gate; pfam07670
1029718003795	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1029718003796	Nucleoside recognition; Region: Gate; pfam07670
1029718003797	FeoA domain; Region: FeoA; pfam04023
1029718003798	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1029718003799	metal binding site [ion binding]; metal-binding site
1029718003800	oligoendopeptidase F; Region: pepF; TIGR00181
1029718003801	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1029718003802	active site
1029718003803	Zn binding site [ion binding]; other site
1029718003804	alpha/beta hydrolase fold; Region: Abhydrolase_1; pfam00561
1029718003805	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1029718003806	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1029718003807	Zn binding site [ion binding]; other site
1029718003808	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
1029718003809	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1029718003810	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1029718003811	DNA binding site [nucleotide binding]
1029718003812	domain linker motif; other site
1029718003813	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
1029718003814	dimerization interface [polypeptide binding]; other site
1029718003815	ligand binding site [chemical binding]; other site
1029718003816	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1029718003817	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1029718003818	HIGH motif; other site
1029718003819	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1029718003820	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1029718003821	active site
1029718003822	KMSKS motif; other site
1029718003823	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1029718003824	tRNA binding surface [nucleotide binding]; other site
1029718003825	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1029718003826	hypothetical protein, pseudogene
1029718003827	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
1029718003828	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
1029718003829	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718003830	ATP binding site [chemical binding]; other site
1029718003831	putative Mg++ binding site [ion binding]; other site
1029718003832	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718003833	nucleotide binding region [chemical binding]; other site
1029718003834	ATP-binding site [chemical binding]; other site
1029718003835	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1029718003836	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1029718003837	active site
1029718003838	HIGH motif; other site
1029718003839	dimer interface [polypeptide binding]; other site
1029718003840	KMSKS motif; other site
1029718003841	Probable zinc-binding domain; Region: zf-trcl; pfam13451
1029718003842	YfhG lipoprotein; Region: Lipoprotein_20; cl08141
1029718003843	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1029718003844	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
1029718003845	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1029718003846	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1029718003847	metal binding site [ion binding]; metal-binding site
1029718003848	active site
1029718003849	I-site; other site
1029718003850	Predicted phosphohydrolase [General function prediction only]; Region: COG1768
1029718003851	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1029718003852	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1029718003853	synthetase active site [active]
1029718003854	NTP binding site [chemical binding]; other site
1029718003855	metal binding site [ion binding]; metal-binding site
1029718003856	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
1029718003857	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
1029718003858	G1 box; other site
1029718003859	putative GEF interaction site [polypeptide binding]; other site
1029718003860	GTP/Mg2+ binding site [chemical binding]; other site
1029718003861	Switch I region; other site
1029718003862	G2 box; other site
1029718003863	G3 box; other site
1029718003864	Switch II region; other site
1029718003865	G4 box; other site
1029718003866	G5 box; other site
1029718003867	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
1029718003868	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
1029718003869	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1029718003870	NAD binding site [chemical binding]; other site
1029718003871	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1029718003872	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1029718003873	active site
1029718003874	HIGH motif; other site
1029718003875	dimer interface [polypeptide binding]; other site
1029718003876	KMSKS motif; other site
1029718003877	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718003878	RNA binding surface [nucleotide binding]; other site
1029718003879	Putative glucoamylase; Region: Glycoamylase; pfam10091
1029718003880	N-terminal domain of glycoside hydrolase family 94 and related domains; Region: GH94N_like; cl17067
1029718003881	Cellobiose phosphorylase [Carbohydrate transport and metabolism]; Region: COG3459
1029718003882	First GH94N domain of cyclic beta 1-2 glucan synthetase and similar domains; Region: GH94N_ChvB_NdvB_1_like; cd11756
1029718003883	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
1029718003884	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
1029718003885	putative catalytic cysteine [active]
1029718003886	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
1029718003887	putative active site [active]
1029718003888	metal binding site [ion binding]; metal-binding site
1029718003889	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
1029718003890	p-Aminobenzoyl-glutamate transporter family; Region: ydaH; TIGR00819
1029718003891	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718003892	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1029718003893	active site
1029718003894	motif I; other site
1029718003895	motif II; other site
1029718003896	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1029718003897	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1029718003898	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1029718003899	active site
1029718003900	substrate binding site [chemical binding]; other site
1029718003901	metal binding site [ion binding]; metal-binding site
1029718003902	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1029718003903	2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Validated; Region: PRK08537
1029718003904	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
1029718003905	Thiamine pyrophosphate (TPP family), 2-oxoglutarate ferredoxin oxidoreductase (OGFOR) subfamily, TPP-binding module; OGFOR catalyzes the oxidative decarboxylation of 2-oxo-acids, with ferredoxin acting as an electron acceptor. In the TCA cycle, OGFOR...; Region: TPP_OGFOR; cd03375
1029718003906	TPP-binding site [chemical binding]; other site
1029718003907	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
1029718003908	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1029718003909	dimer interface [polypeptide binding]; other site
1029718003910	PYR/PP interface [polypeptide binding]; other site
1029718003911	TPP binding site [chemical binding]; other site
1029718003912	substrate binding site [chemical binding]; other site
1029718003913	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1029718003914	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1029718003915	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1029718003916	Uncharacterized conserved protein [Function unknown]; Region: COG1624
1029718003917	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1029718003918	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1029718003919	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1029718003920	catalytic residues [active]
1029718003921	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1029718003922	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1029718003923	active site
1029718003924	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
1029718003925	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
1029718003926	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
1029718003927	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1029718003928	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Region: CitX; cl01498
1029718003929	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1029718003930	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1029718003931	active site
1029718003932	metal binding site [ion binding]; metal-binding site
1029718003933	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1029718003934	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1029718003935	23S rRNA interface [nucleotide binding]; other site
1029718003936	L3 interface [polypeptide binding]; other site
1029718003937	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1029718003938	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1029718003939	dimerization interface 3.5A [polypeptide binding]; other site
1029718003940	active site
1029718003941	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1029718003942	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637
1029718003943	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1029718003944	Walker A/P-loop; other site
1029718003945	ATP binding site [chemical binding]; other site
1029718003946	Q-loop/lid; other site
1029718003947	ABC transporter signature motif; other site
1029718003948	Walker B; other site
1029718003949	D-loop; other site
1029718003950	H-loop/switch region; other site
1029718003951	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
1029718003952	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1029718003953	Walker A/P-loop; other site
1029718003954	ATP binding site [chemical binding]; other site
1029718003955	Q-loop/lid; other site
1029718003956	ABC transporter signature motif; other site
1029718003957	Walker B; other site
1029718003958	D-loop; other site
1029718003959	H-loop/switch region; other site
1029718003960	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1029718003961	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1029718003962	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1029718003963	alphaNTD homodimer interface [polypeptide binding]; other site
1029718003964	alphaNTD - beta interaction site [polypeptide binding]; other site
1029718003965	alphaNTD - beta' interaction site [polypeptide binding]; other site
1029718003966	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1029718003967	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1029718003968	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1029718003969	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718003970	RNA binding surface [nucleotide binding]; other site
1029718003971	30S ribosomal protein S11; Validated; Region: PRK05309
1029718003972	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
1029718003973	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1029718003974	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1029718003975	rRNA binding site [nucleotide binding]; other site
1029718003976	predicted 30S ribosome binding site; other site
1029718003977	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1029718003978	active site
1029718003979	adenylate kinase; Reviewed; Region: adk; PRK00279
1029718003980	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1029718003981	AMP-binding site [chemical binding]; other site
1029718003982	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1029718003983	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1029718003984	SecY translocase; Region: SecY; pfam00344
1029718003985	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1029718003986	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1029718003987	23S rRNA binding site [nucleotide binding]; other site
1029718003988	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1029718003989	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1029718003990	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1029718003991	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1029718003992	5S rRNA interface [nucleotide binding]; other site
1029718003993	23S rRNA interface [nucleotide binding]; other site
1029718003994	L5 interface [polypeptide binding]; other site
1029718003995	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1029718003996	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1029718003997	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1029718003998	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1029718003999	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1029718004000	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1029718004001	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1029718004002	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1029718004003	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1029718004004	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1029718004005	RNA binding site [nucleotide binding]; other site
1029718004006	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1029718004007	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1029718004008	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1029718004009	putative translocon interaction site; other site
1029718004010	23S rRNA interface [nucleotide binding]; other site
1029718004011	signal recognition particle (SRP54) interaction site; other site
1029718004012	L23 interface [polypeptide binding]; other site
1029718004013	trigger factor interaction site; other site
1029718004014	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1029718004015	23S rRNA interface [nucleotide binding]; other site
1029718004016	5S rRNA interface [nucleotide binding]; other site
1029718004017	putative antibiotic binding site [chemical binding]; other site
1029718004018	L25 interface [polypeptide binding]; other site
1029718004019	L27 interface [polypeptide binding]; other site
1029718004020	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1029718004021	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1029718004022	G-X-X-G motif; other site
1029718004023	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1029718004024	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1029718004025	putative translocon binding site; other site
1029718004026	protein-rRNA interface [nucleotide binding]; other site
1029718004027	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1029718004028	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1029718004029	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1029718004030	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1029718004031	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1029718004032	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1029718004033	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1029718004034	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1029718004035	elongation factor Tu; Reviewed; Region: PRK00049
1029718004036	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1029718004037	G1 box; other site
1029718004038	GEF interaction site [polypeptide binding]; other site
1029718004039	GTP/Mg2+ binding site [chemical binding]; other site
1029718004040	Switch I region; other site
1029718004041	G2 box; other site
1029718004042	G3 box; other site
1029718004043	Switch II region; other site
1029718004044	G4 box; other site
1029718004045	G5 box; other site
1029718004046	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1029718004047	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1029718004048	Antibiotic Binding Site [chemical binding]; other site
1029718004049	elongation factor G; Reviewed; Region: PRK00007
1029718004050	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1029718004051	G1 box; other site
1029718004052	putative GEF interaction site [polypeptide binding]; other site
1029718004053	GTP/Mg2+ binding site [chemical binding]; other site
1029718004054	Switch I region; other site
1029718004055	G2 box; other site
1029718004056	G3 box; other site
1029718004057	Switch II region; other site
1029718004058	G4 box; other site
1029718004059	G5 box; other site
1029718004060	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1029718004061	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1029718004062	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1029718004063	30S ribosomal protein S7; Validated; Region: PRK05302
1029718004064	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1029718004065	S17 interaction site [polypeptide binding]; other site
1029718004066	S8 interaction site; other site
1029718004067	16S rRNA interaction site [nucleotide binding]; other site
1029718004068	streptomycin interaction site [chemical binding]; other site
1029718004069	23S rRNA interaction site [nucleotide binding]; other site
1029718004070	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1029718004071	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1029718004072	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1029718004073	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1029718004074	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1029718004075	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1029718004076	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1029718004077	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1029718004078	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1029718004079	G-loop; other site
1029718004080	DNA binding site [nucleotide binding]
1029718004081	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1029718004082	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1029718004083	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1029718004084	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1029718004085	RPB1 interaction site [polypeptide binding]; other site
1029718004086	RPB10 interaction site [polypeptide binding]; other site
1029718004087	RPB11 interaction site [polypeptide binding]; other site
1029718004088	RPB3 interaction site [polypeptide binding]; other site
1029718004089	RPB12 interaction site [polypeptide binding]; other site
1029718004090	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1029718004091	core dimer interface [polypeptide binding]; other site
1029718004092	peripheral dimer interface [polypeptide binding]; other site
1029718004093	L10 interface [polypeptide binding]; other site
1029718004094	L11 interface [polypeptide binding]; other site
1029718004095	putative EF-Tu interaction site [polypeptide binding]; other site
1029718004096	putative EF-G interaction site [polypeptide binding]; other site
1029718004097	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1029718004098	23S rRNA interface [nucleotide binding]; other site
1029718004099	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1029718004100	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1029718004101	mRNA/rRNA interface [nucleotide binding]; other site
1029718004102	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1029718004103	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1029718004104	23S rRNA interface [nucleotide binding]; other site
1029718004105	L7/L12 interface [polypeptide binding]; other site
1029718004106	putative thiostrepton binding site; other site
1029718004107	L25 interface [polypeptide binding]; other site
1029718004108	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1029718004109	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1029718004110	putative homodimer interface [polypeptide binding]; other site
1029718004111	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1029718004112	heterodimer interface [polypeptide binding]; other site
1029718004113	homodimer interface [polypeptide binding]; other site
1029718004114	SecE/Sec61-gamma subunits of protein translocation complex; Region: SecE; pfam00584
1029718004115	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1029718004116	elongation factor Tu; Reviewed; Region: PRK00049
1029718004117	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1029718004118	G1 box; other site
1029718004119	GEF interaction site [polypeptide binding]; other site
1029718004120	GTP/Mg2+ binding site [chemical binding]; other site
1029718004121	Switch I region; other site
1029718004122	G2 box; other site
1029718004123	G3 box; other site
1029718004124	Switch II region; other site
1029718004125	G4 box; other site
1029718004126	G5 box; other site
1029718004127	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1029718004128	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1029718004129	Antibiotic Binding Site [chemical binding]; other site
1029718004130	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1029718004131	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1029718004132	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
1029718004133	DNA binding residues [nucleotide binding]
1029718004134	YacP-like NYN domain; Region: NYN_YacP; pfam05991
1029718004135	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1029718004136	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1029718004137	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1029718004138	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1029718004139	active site
1029718004140	metal binding site [ion binding]; metal-binding site
1029718004141	dimerization interface [polypeptide binding]; other site
1029718004142	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
1029718004143	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1029718004144	active site
1029718004145	HIGH motif; other site
1029718004146	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1029718004147	KMSKS motif; other site
1029718004148	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
1029718004149	tRNA binding surface [nucleotide binding]; other site
1029718004150	anticodon binding site; other site
1029718004151	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1029718004152	substrate binding site; other site
1029718004153	dimer interface; other site
1029718004154	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1029718004155	Clp amino terminal domain; Region: Clp_N; pfam02861
1029718004156	Clp amino terminal domain; Region: Clp_N; pfam02861
1029718004157	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004158	Walker A motif; other site
1029718004159	ATP binding site [chemical binding]; other site
1029718004160	Walker B motif; other site
1029718004161	arginine finger; other site
1029718004162	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004163	Walker A motif; other site
1029718004164	ATP binding site [chemical binding]; other site
1029718004165	Walker B motif; other site
1029718004166	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1029718004167	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
1029718004168	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1029718004169	ADP binding site [chemical binding]; other site
1029718004170	phosphagen binding site; other site
1029718004171	substrate specificity loop; other site
1029718004172	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1029718004173	UvrB/uvrC motif; Region: UVR; pfam02151
1029718004174	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1029718004175	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1029718004176	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1029718004177	DNA polymerase III, delta subunit; Region: DNA_pol3_delta2; pfam13177
1029718004178	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1029718004179	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
1029718004180	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1029718004181	TMP-binding site; other site
1029718004182	ATP-binding site [chemical binding]; other site
1029718004183	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1029718004184	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1029718004185	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1029718004186	catalytic residue [active]
1029718004187	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1029718004188	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1029718004189	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1029718004190	Cl binding site [ion binding]; other site
1029718004191	oligomer interface [polypeptide binding]; other site
1029718004192	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
1029718004193	dimer interface [polypeptide binding]; other site
1029718004194	catalytic triad [active]
1029718004195	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK01710
1029718004196	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1029718004197	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718004198	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1029718004199	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1029718004200	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1029718004201	motif 1; other site
1029718004202	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1029718004203	active site
1029718004204	motif 2; other site
1029718004205	motif 3; other site
1029718004206	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
1029718004207	anticodon binding site; other site
1029718004208	endopeptidase Clp ATP-binding regulatory subunit (clpX); Region: clpX; TIGR00382
1029718004209	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004210	Walker A motif; other site
1029718004211	ATP binding site [chemical binding]; other site
1029718004212	Walker B motif; other site
1029718004213	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1029718004214	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1029718004215	dimer interface [polypeptide binding]; other site
1029718004216	putative anticodon binding site; other site
1029718004217	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1029718004218	motif 1; other site
1029718004219	active site
1029718004220	motif 2; other site
1029718004221	motif 3; other site
1029718004222	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1029718004223	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1029718004224	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1029718004225	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1029718004226	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1029718004227	FMN binding site [chemical binding]; other site
1029718004228	active site
1029718004229	catalytic residues [active]
1029718004230	substrate binding site [chemical binding]; other site
1029718004231	FtsH Extracellular; Region: FtsH_ext; pfam06480
1029718004232	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1029718004233	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004234	Walker A motif; other site
1029718004235	ATP binding site [chemical binding]; other site
1029718004236	Walker B motif; other site
1029718004237	arginine finger; other site
1029718004238	Peptidase family M41; Region: Peptidase_M41; pfam01434
1029718004239	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718004240	active site
1029718004241	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1029718004242	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1029718004243	Ligand Binding Site [chemical binding]; other site
1029718004244	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1029718004245	stage II sporulation protein E; Region: spore_II_E; TIGR02865
1029718004246	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1029718004247	hypothetical protein; Provisional; Region: PRK05807
1029718004248	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1029718004249	RNA binding site [nucleotide binding]; other site
1029718004250	Septum formation initiator; Region: DivIC; cl17659
1029718004251	Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; cl09801
1029718004252	YabP family; Region: YabP; cl06766
1029718004253	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1029718004254	RNA binding surface [nucleotide binding]; other site
1029718004255	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1029718004256	IHF dimer interface [polypeptide binding]; other site
1029718004257	IHF - DNA interface [nucleotide binding]; other site
1029718004258	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1029718004259	stage V sporulation protein T; Region: spore_V_T; TIGR02851
1029718004260	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
1029718004261	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1029718004262	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1029718004263	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
1029718004264	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1029718004265	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1029718004266	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1029718004267	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1029718004268	ATP binding site [chemical binding]; other site
1029718004269	putative Mg++ binding site [ion binding]; other site
1029718004270	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1029718004271	nucleotide binding region [chemical binding]; other site
1029718004272	ATP-binding site [chemical binding]; other site
1029718004273	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
1029718004274	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1029718004275	putative active site [active]
1029718004276	catalytic residue [active]
1029718004277	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1029718004278	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1029718004279	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1029718004280	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1029718004281	dimerization interface [polypeptide binding]; other site
1029718004282	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1029718004283	dimer interface [polypeptide binding]; other site
1029718004284	phosphorylation site [posttranslational modification]
1029718004285	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1029718004286	ATP binding site [chemical binding]; other site
1029718004287	Mg2+ binding site [ion binding]; other site
1029718004288	G-X-G motif; other site
1029718004289	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1029718004290	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1029718004291	active site
1029718004292	phosphorylation site [posttranslational modification]
1029718004293	intermolecular recognition site; other site
1029718004294	dimerization interface [polypeptide binding]; other site
1029718004295	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1029718004296	DNA binding site [nucleotide binding]
1029718004297	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1029718004298	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1029718004299	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1029718004300	active site
1029718004301	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1029718004302	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1029718004303	Substrate binding site; other site
1029718004304	Mg++ binding site; other site
1029718004305	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
1029718004306	putative trimer interface [polypeptide binding]; other site
1029718004307	putative CoA binding site [chemical binding]; other site
1029718004308	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1029718004309	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1029718004310	putative dimer interface [polypeptide binding]; other site
1029718004311	putative anticodon binding site; other site
1029718004312	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1029718004313	homodimer interface [polypeptide binding]; other site
1029718004314	motif 1; other site
1029718004315	motif 2; other site
1029718004316	active site
1029718004317	motif 3; other site
1029718004318	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1029718004319	Calcineurin-like phosphoesterase superfamily domain; Region: Metallophos_2; pfam12850
1029718004320	active site
1029718004321	metal binding site [ion binding]; metal-binding site
1029718004322	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1029718004323	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1029718004324	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1029718004325	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1029718004326	regulatory protein SpoVG; Reviewed; Region: PRK13259
1029718004327	multifunctional aminopeptidase A; Provisional; Region: PRK00913
1029718004328	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
1029718004329	interface (dimer of trimers) [polypeptide binding]; other site
1029718004330	Substrate-binding/catalytic site; other site
1029718004331	Zn-binding sites [ion binding]; other site
1029718004332	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1029718004333	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
1029718004334	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1029718004335	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1029718004336	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1029718004337	Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair]; Region: COG1658
1029718004338	active site
1029718004339	metal binding site [ion binding]; metal-binding site
1029718004340	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1029718004341	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1029718004342	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1029718004343	G5 domain; Region: G5; pfam07501
1029718004344	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1029718004345	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1029718004346	active site
1029718004347	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1029718004348	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1029718004349	PYR/PP interface [polypeptide binding]; other site
1029718004350	dimer interface [polypeptide binding]; other site
1029718004351	TPP binding site [chemical binding]; other site
1029718004352	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1029718004353	transketolase; Reviewed; Region: PRK05899
1029718004354	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1029718004355	TPP-binding site [chemical binding]; other site
1029718004356	dimer interface [polypeptide binding]; other site
1029718004357	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1029718004358	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1029718004359	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
1029718004360	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1029718004361	Domain of unknown function (DUF3783); Region: DUF3783; pfam12646
1029718004362	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1029718004363	glutamine synthetase, type I; Region: GlnA; TIGR00653
1029718004364	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1029718004365	Uncharacterized membrane protein [Function unknown]; Region: COG3949
1029718004366	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1029718004367	hypothetical protein; Provisional; Region: PRK13661
1029718004368	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1029718004369	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1029718004370	Walker A/P-loop; other site
1029718004371	ATP binding site [chemical binding]; other site
1029718004372	Q-loop/lid; other site
1029718004373	ABC transporter signature motif; other site
1029718004374	Walker B; other site
1029718004375	D-loop; other site
1029718004376	H-loop/switch region; other site
1029718004377	ATP-binding cassette cobalt transporter; Region: DUF3744; pfam12558
1029718004378	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1029718004379	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1029718004380	Walker A/P-loop; other site
1029718004381	ATP binding site [chemical binding]; other site
1029718004382	Q-loop/lid; other site
1029718004383	ABC transporter signature motif; other site
1029718004384	Walker B; other site
1029718004385	D-loop; other site
1029718004386	H-loop/switch region; other site
1029718004387	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1029718004388	Sulfatase; Region: Sulfatase; cl17466
1029718004389	methionyl-tRNA synthetase; Reviewed; Region: PRK11893
1029718004390	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1029718004391	active site
1029718004392	HIGH motif; other site
1029718004393	KMSKS motif; other site
1029718004394	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1029718004395	tRNA binding surface [nucleotide binding]; other site
1029718004396	anticodon binding site; other site
1029718004397	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
1029718004398	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
1029718004399	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
1029718004400	ATP-dependent protease, Lon family; Region: spore_lon_C; TIGR02903
1029718004401	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004402	Walker A motif; other site
1029718004403	ATP binding site [chemical binding]; other site
1029718004404	Walker B motif; other site
1029718004405	arginine finger; other site
1029718004406	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1029718004407	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1029718004408	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1029718004409	non-specific DNA binding site [nucleotide binding]; other site
1029718004410	salt bridge; other site
1029718004411	sequence-specific DNA binding site [nucleotide binding]; other site
1029718004412	Cupin domain; Region: Cupin_2; pfam07883
1029718004413	replicative DNA helicase; Region: DnaB; TIGR00665
1029718004414	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1029718004415	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1029718004416	Walker A motif; other site
1029718004417	ATP binding site [chemical binding]; other site
1029718004418	Walker B motif; other site
1029718004419	DNA binding loops [nucleotide binding]
1029718004420	Predicted SPOUT methyltransferase; Region: SPOUT_MTase; cl00679
1029718004421	Predicted SPOUT methyltransferase; Region: SPOUT_MTase; cl00679
1029718004422	hypothetical protein; Provisional; Region: PRK05590
1029718004423	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1029718004424	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1029718004425	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1029718004426	hinge; other site
1029718004427	active site
1029718004428	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1029718004429	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cd00306
1029718004430	active site
1029718004431	catalytic residues [active]
1029718004432	Arginine N-succinyltransferase beta subunit; Region: AstA; cl11440
1029718004433	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1029718004434	Peptidase family M23; Region: Peptidase_M23; pfam01551
1029718004435	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1029718004436	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
1029718004437	DNA replication protein DnaC; Validated; Region: PRK06835
1029718004438	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1029718004439	Walker A motif; other site
1029718004440	ATP binding site [chemical binding]; other site
1029718004441	Walker B motif; other site
1029718004442	arginine finger; other site
1029718004443	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1029718004444	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1029718004445	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1029718004446	dimer interface [polypeptide binding]; other site
1029718004447	ssDNA binding site [nucleotide binding]; other site
1029718004448	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1029718004449	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1029718004450	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1029718004451	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1029718004452	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1029718004453	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1029718004454	catalytic residue [active]
1029718004455	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1029718004456	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1029718004457	P-loop; other site
1029718004458	Magnesium ion binding site [ion binding]; other site
1029718004459	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
1029718004460	Magnesium ion binding site [ion binding]; other site
1029718004461	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1029718004462	ParB-like nuclease domain; Region: ParB; smart00470
1029718004463	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1029718004464	amidase catalytic site [active]
1029718004465	Zn binding residues [ion binding]; other site
1029718004466	substrate binding site [chemical binding]; other site
1029718004467	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1029718004468	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1029718004469	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1029718004470	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
1029718004471	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1029718004472	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1029718004473	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1029718004474	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1029718004475	G1 box; other site
1029718004476	GTP/Mg2+ binding site [chemical binding]; other site
1029718004477	Switch I region; other site
1029718004478	G2 box; other site
1029718004479	Switch II region; other site
1029718004480	G3 box; other site
1029718004481	G4 box; other site
1029718004482	G5 box; other site
1029718004483	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1029718004484	60Kd inner membrane protein; Region: 60KD_IMP; cl00489
1029718004485	Haemolytic domain; Region: Haemolytic; pfam01809
1029718004486	ribonuclease P; Reviewed; Region: rnpA; PRK00499
1029718004487	Ribosomal protein L34; Region: Ribosomal_L34; cl00370