-- dump date 20140619_024539 -- class Genbank::CDS -- table cds_note -- id note YP_265429.2 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_265431.1 catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive YP_265438.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_265439.1 possibly viral YP_265440.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_265446.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_265448.1 FtsQ YP_265456.1 murE and murF fusion YP_265457.1 penicillin-binding protein 2 YP_265458.1 ingrowth of wall at septum YP_265460.1 FtsZ YP_265461.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_265462.1 probable ybjR YP_265464.1 Ttg2 Family, yrbC similar to toluene tolerance protein YP_265465.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_265466.1 probable dnaG YP_265486.1 Type IV fimbrial assembly protein, pilC YP_265487.1 Type IV pilus assembly protein (ATPase) PilB YP_265488.1 Type IV fimbrial biogenesis protein PilQ YP_265491.1 Type IV pilus biogenesis protein, PilM/PilN fusion YP_265492.1 GAF photoreceptor fused to PP2C YP_265493.1 Type IV Prepilin Peptidase A24A YP_265495.1 Type IV fimbrial biogenesis protein, PilY1 YP_265498.1 pilW-like YP_265499.1 similar to PilV YP_265500.1 pilU-like YP_265501.1 Type IV pilus retraction ATPase PilT YP_265508.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_265511.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_265513.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_265514.1 MarR family (Pfam) YP_265515.1 OmpR family, response regulator, ompR YP_265518.1 lgt (umpA) YP_265520.1 YfiH family COG1496 YP_265523.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_265524.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_265529.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_265534.1 bacteriophage-type YP_265540.1 thiol-disulfide interchange protein YP_265543.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_265544.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_265552.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine YP_265556.1 biogenesis of cytochrome oxidase c YP_265557.1 similar to subunit III, coxC Rickettsia YP_265558.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_265561.1 chain I YP_265565.1 MarR family (Interpro) YP_265568.1 GltB-like protein YP_265583.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family; some organisms carry two different copies of this enzyme YP_265589.1 rhlE YP_265590.1 TypA YP_265593.1 flavin-containing (Fugue) YP_265595.1 TldD YP_265601.1 GmdA YP_265603.1 DnaJ N Terminal End Only YP_265613.1 rhodanese-like, sseA (KEGG b2521) YP_265614.1 YhiI YP_265616.1 similar to slt domain (Fugue) YP_265622.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_265627.1 BioY family (Pfam) YP_265630.1 transforms a conserved lysine residue of initiation factor 5A into deoxyhypusine YP_265632.1 YhhQ YP_265635.1 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine YP_265636.1 TrkH YP_265637.1 AmpG YP_265638.1 SH3 and NLP/P60 domains (Pfam) YP_265641.1 Catalyzes the conversion of acetyl-CoA and L-homoserine to CoA and O-acetyl-L-homoserine YP_265642.1 MetW YP_265645.1 involved in the peptidyltransferase reaction during translation YP_265646.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_265654.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_265655.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_265656.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_265661.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_265666.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_265667.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_265671.1 DmdA; DMSP demethylase; in Silicibacter knockout of this gene results in an inability to convert DMSP to methanethiol which is restored with a cloned copy of the gene YP_265672.1 alpha/beta hydrolase fold family YP_265677.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_265678.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_265685.1 Drug/Metabolite Exporter family YP_265687.1 unknown specificity; similar to gatA YP_265688.1 large chain YP_265689.1 small chain YP_265691.1 ATP-binding protein, molybdenum/tungsten binding YP_265692.1 ATP-binding protein, molybdenum/tungsten binding YP_265693.1 inner membrane component YP_265701.1 GlcE YP_265702.1 GlcD YP_265704.1 IldD YP_265710.1 CcmD YP_265711.1 CcmC YP_265713.1 Involved in cell division; probably involved in intracellular septation YP_265722.1 possible blue light photoreceptor cryptochrome YP_265726.1 DedA family, yqaA YP_265728.2 unknown specificity YP_265732.1 similar to Rhodopseudomonas palustris CGA009 gi|39647338|emb|CAE25859.1 YP_265748.1 similar to the N-terminal domain of Lon protease YP_265758.1 half of bifunctional hisB YP_265759.1 heat shock protein involved in degradation of misfolded proteins YP_265760.1 heat shock protein involved in degradation of misfolded proteins YP_265764.1 SecB YP_265765.1 epsilon chain, dnaQ YP_265771.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_265773.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_265774.1 SPINDLY family YP_265776.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_265780.1 delta subunit, holA YP_265788.1 C-terminal effector YP_265792.1 DnaJ YP_265793.1 DnaK (Heat shock protein 70, hsp70) YP_265798.1 possible periplasmic protein YP_265799.2 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_265801.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_265805.1 similar to unknown environmental sequence YP_265807.1 MiaB YP_265811.1 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_265821.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_265822.1 Fur-like protein YP_265827.1 MoeB YP_265830.2 AarF YP_265835.2 beta chain, dnaN YP_265845.1 DsbB YP_265846.1 DedA YP_265848.1 similar to Myxococcus xanthus CarD; similar to COG1329: Transcriptional regulators YP_265856.1 Drug/Metabolite Exporter family YP_265858.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_265862.1 group 1 family protein YP_265866.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_265867.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_265869.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_265875.1 dnaJ-related YP_265887.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_265888.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_265889.1 subfamily IA, variant 3 YP_265891.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_265897.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_265903.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_265904.1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine YP_265905.1 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ YP_265907.1 possible atypical protein kinase YP_265913.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_265920.1 YhbG YP_265933.1 YbaB family COG0 YP_265935.1 catalyzes the formation of malate from glyoxylate and acetyl-CoA YP_265936.1 similar to carboxyltransferase alpha chain - Aquifex aeolicus YP_265939.1 similar to protein of unknown function (DUF1178) YP_265940.1 Involved in ubiquinone biosynthesis YP_265942.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_265945.1 similar to hypothetical protein EBAC000-62A03.2 YP_265947.1 protein function by Fugue structure prediction YP_265955.1 3-oxoacyl-[acyl-carrier-protein] reductase YP_265962.1 GalE-like protein YP_265995.1 substrain RIMD 0509952 YP_265998.1 C-terminal YP_266001.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_266003.2 similar to protein of unknown function (DUF1013) YP_266004.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_266008.1 similar to non-muscle-type fructose-bisphosphate aldolase from Pacific lamprey YP_266011.1 thiamine diphosphate binding domain YP_266013.1 similar to family of unknown function (DUF710) YP_266018.1 substrain RIMD 0509952 YP_266021.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_266023.1 similar to COG1729: Uncharacterized protein conserved in bacteria YP_266029.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_266030.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_266034.2 substrain RIMD 0509952 YP_266035.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_266036.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_266040.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_266041.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_266042.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_266044.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_266046.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_266048.1 similar to COG0365: Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases YP_266050.1 similar to 2Fe-2S Caulobacter crescentus CB15 YP_266059.1 similar to COG1974: SOS-response transcriptional repressors (RecA-mediated autopeptidases) YP_266061.1 similar to protein of unknown function DUF636 YP_266065.1 trypsin-like serine and cysteine proteases YP_266067.1 Converts isocitrate to alpha ketoglutarate YP_266068.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_266074.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_266081.1 probable high-affinity branched-chain amino acid transport ATP-binding protein YP_266091.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_266093.1 similar to protein of unknown function (DUF1365) YP_266094.1 cfa-like protein YP_266098.1 similar to FAD dependent oxidoreductase family YP_266099.1 similar to COG4627: Uncharacterized protein conserved in bacteria YP_266100.1 similar to Bacillus cereus ATCC 14579 sp|Q813A5|YY99_BACCR hypothetical UPF006 YP_266106.1 similar to COG0746: Molybdopterin-guanine dinucleotide biosynthesis protein A YP_266113.1 similar to hypothetical protein EBAC750-09G06.38 from uncultured bacterium 314 YP_266114.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_266117.1 similar to mfs superfamily YP_266118.1 similar to COG0697: Permeases of the drug/metabolite transporter (DMT) superfamily YP_266138.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_266144.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_266145.1 possibly vitamin B12-dependent YP_266147.1 similar to Caulobacter crescentus CB15 gi|25397377|pir||A87483 hypothetical protein CC1 YP_266149.1 AccB YP_266150.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_266152.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_266153.1 rne/rng YP_266158.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_266161.1 with SufCD activates cysteine desulfurase SufS YP_266164.1 similar to Escherichia coli csdB, nifs Family YP_266165.1 involved in Fe-S cluster formation YP_266171.1 membrane spanning protein YP_266176.1 similar to COG3492: Uncharacterized protein conserved in bacteria YP_266180.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_266184.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_266188.1 unknown specificity YP_266191.1 permease component YP_266192.1 permease component YP_266193.1 ATP-binding protein YP_266194.1 unknown specificity YP_266195.1 catalyzes the formation of 3-methyl-2-oxobutanoate from 2,3,-dihydroxy-3-methylbutanoate YP_266201.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_266203.1 renamed azoR YP_266204.1 inositol monophosphatase family YP_266207.1 quaternary ammonium compounds YP_266210.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_266218.1 periplasmic components; similar to COG2113: ABC-type proline/glycine betaine transport systems YP_266222.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_266229.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_266232.1 possible urea transporter (Pfam) YP_266234.1 ABC-2-type transport system YP_266235.1 similar to prokaryotic and plant carbonic anhydrase YP_266237.1 similar to Escherichia coli hupA and hupB YP_266253.1 class IV YP_266257.1 catalyzes the reduction of adenosine 5'-phosphosulfate to AMP and sulfite YP_266264.1 catalyzes the formation of acetyl phosphate and sulfite from 2-sulfoacetaldehyde; is active when grown on taurine as a sole carbon source YP_266266.1 unknown specificity YP_266268.1 permease involved in lysophospholipase L1 biosynthesis YP_266274.1 M23/M37 family YP_266275.1 unknown specificity YP_266278.1 contains rhodanese domain YP_266280.1 unknown specificity YP_266282.1 3-hydroxyisobutyrate dehydrogenase family YP_266283.1 similar to COG4663: TRAP-type mannitol/chloroaromatic compound transport system YP_266284.2 small permease component YP_266285.1 large chain YP_266287.1 uracil, thiamine, allantoin YP_266288.1 unknown specificity YP_266297.1 active site peptidylprolyl isomerase YP_266299.1 binds and unfolds substrates as part of the ClpXP protease YP_266300.1 Lon YP_266302.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_266304.1 Catalyzes the transfer of electrons from NADH to quinone YP_266306.1 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase YP_266307.1 Catalyzes the transfer of electrons from NADH to quinone YP_266309.1 Catalyzes the transfer of electrons from NADH to quinone YP_266313.1 Catalyzes the transfer of electrons from NADH to quinone YP_266314.1 Catalyzes the transfer of electrons from NADH to quinone YP_266316.1 Bordetella pertussis Bvg accessory factor YP_266319.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_266320.1 membrane spanning protein YP_266328.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_266337.1 Represses a number of genes involved in the response to DNA damage YP_266345.1 similar to COG1538: Outer membrane protein.; Similar to TolC by Fugue analysis. YP_266348.1 VCBS domain, Interpro ID: ipr010221; similar to COG3468: Type V secretory pathway, adhesin AidA YP_266349.1 similar to COG0845: Membrane-fusion protein YP_266350.1 similar to COG0845: Membrane-fusion protein YP_266353.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_266354.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_266355.1 C-terminal TIM barrel domain YP_266357.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_266358.1 similar to Atu1441 YP_266361.1 Includes: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; similar to Swiss-Prot Accession Number Q9PM68 YP_266364.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_266366.1 similar to amino acid binding protein Mesorhizobium loti YP_266367.1 similar to permease protein VC1361 Vibrio cholerae (strain N16961) YP_266373.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_266384.1 family 3 YP_266396.1 helix-destabilizing protein YP_266407.1 similar to Shewanella oneidensis MR-1 gb|AAN55045.1 YP_266411.1 delta prime subunit YP_266419.1 in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope YP_266420.1 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese YP_266422.1 C subunit, N-terminal YP_266424.1 Xylanase/chitin deacetylase family enzyme YP_266425.1 similar to Escherichia coli gb|AAL67563.1 YP_266434.1 similar to Pseudomonas aeruginosa PA01 pir||A83623 YP_266439.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_266441.1 similar to BA483f11.2.1 cox15 (yeast) YP_266444.1 merR family YP_266447.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_266450.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_266455.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_266461.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_266466.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_266467.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_266470.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_266471.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_266481.1 similar to Geobacter sulfurreducens PCA gb|AAR36025.1| MATE efflux family protein YP_266482.1 similar to Shewanella oneidensis MR-1 sp|Q8EES8|YM90_SHEON hypothetical UPF0176 protein YP_266484.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_266501.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_266502.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_266503.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_266507.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_266512.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_266517.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_266521.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_266526.1 substrain RIMD 0 YP_266527.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_266528.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_266537.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_266539.1 catalyzes the phosphorylation of NAD to NADP YP_266540.1 similar to Clostridium perfringens dbj|BAB80118.1| YP_266541.1 similar to COG1058: Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA YP_266545.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_266546.1 purQ-like protein YP_266552.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_266554.1 catalyzes the formation of 2-isopropylmalate from 1-methyl-2-oxobutanoate and acetyl-CoA YP_266563.1 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate YP_266565.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_266566.1 Catalyzes the rate-limiting step in dNTP synthesis YP_266569.1 ATPase involved in DNA repair YP_266577.1 RecB and DNA/RNA helicase YP_266581.1 similar to Oceanobacillus iheyensis HTE831 dbj|BAC12647.1 YP_266583.1 similar to COG5515: Uncharacterized conserved small protein YP_266586.1 similar to ATP-binding protein Caulobacter crescentus CB15, pstB YP_266589.1 periplasmic phosphate-binding protein PstS YP_266590.1 two-component sensor histidine kinase, phoR Mesorhizobium loti YP_266591.1 similar to Leptospira interrogans serovar lai str. 56601 gb|AAN50992.1 YP_266594.1 similar to COG2814: Arabinose efflux permease YP_266597.1 similar to pentapeptide repeats protein from uncultured bacterium 314 YP_266610.1 similar to Nitrosomonas europaea ATCC 19718 emb|CAD84691.1 YP_266615.1 aidB (acyl-CoA) regulator YP_266619.1 permease protein YP_266620.1 periplasmic amino acid-binding protein YP_266623.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_266634.1 similar to Sinorhizobium meliloti pir||E95408 YP_266638.1 glyoxalase II YP_266644.1 similar to ATP-binding protein Vibrio vulnificus YJ016 dbj|BAC95508.1 YP_266645.1 similar to permease protein VC0609 Vibrio cholerae YP_266654.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_266655.1 similar to COG3651: Uncharacterized protein conserved in bacteria YP_266661.1 similar to mitochondrial precursor (me2glydh) - Agrobacterium tumefaciens YP_266663.1 similar to YabF family Clostridium acetobutylicum pir||B96902 probable NADP YP_266665.1 similar to COG2391: Predicted transporter component YP_266677.1 similar to Pseudomonas putida KT2440 gb|AAN68299.1 YP_266685.1 similar to Swiss-Prot Accession Number P29079 YP_266688.1 similar to probable integral membrane protein Mesorhizobium loti dbj|BAB50359.1 YP_266689.1 gamma subunit family YP_266698.1 similar to COG4663: TRAP-type mannitol/chloroaromatic compound transport system YP_266699.1 TrapT family, dctM subunit YP_266716.1 GlxD-like protein YP_266722.1 GXGXG motif YP_266725.1 catalyzes the formation of pyruvate from 2,3-diaminopropionate YP_266733.1 LysE family YP_266753.1 similar to COG0683: ABC-type branched-chain amino acid transport systems, periplasmic component YP_266754.1 similar to COG0730: Predicted permeases YP_266760.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_266761.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_266769.1 possible threonine efflux pump YP_266780.1 functions in MreBCD complex in some organisms