-- dump date 20140619_040258 -- class Genbank::CDS -- table cds_note -- id note NP_828876.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate NP_828877.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm NP_828879.1 contains N-terminal domain of unknown function fused to transcription elongation factor; GreA is necessary for efficient RNA polymerization through arresting sites; cleaves the nascent transcript and allows resumption of transcription elongation NP_828880.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate NP_828881.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall NP_828882.1 identified by match to TIGR protein family HMM TIGR01866 NP_828883.1 similar to GB:L25079, SP:P42822, and PID:529423; identified by sequence similarity NP_828884.1 identified by match to PFAM protein family HMM PF02405 NP_828885.1 similar to SP:P13128, GB:X15127, and GB:X60035; identified by sequence similarity NP_828886.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination NP_828887.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues NP_828888.1 similar to GP:7190941; identified by sequence similarity NP_828889.1 similar to SP:P14916, GB:X17079, PID:149010, PID:43634, PID:1567116, PID:2313154, SP:P14916, GB:X17079, PID:149010, PID:43634, PID:1567116, and PID:2313154; identified by sequence similarity NP_828890.1 similar to SP:P14916, GB:X17079, PID:149010, PID:43634, PID:1567116, PID:2313154, SP:P14916, GB:X17079, PID:149010, PID:43634, PID:1567116, and PID:2313154; identified by sequence similarity NP_828891.1 similar to SP:Q03523, GB:Z25865, and GB:Z15056; identified by sequence similarity NP_828892.1 similar to GP:8979098; identified by sequence similarity NP_828893.1 similar to SP:Q03523, GB:Z25865, and GB:Z15056; identified by sequence similarity NP_828894.1 similar to SP:Q03523, GB:Z25865, and GB:Z15056; identified by sequence similarity NP_828895.1 similar to GB:D26185, SP:P23261, GB:M58592, PID:143664, PID:467338, and GB:AL009126; identified by sequence similarity NP_828896.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis NP_828897.1 similar to GB:L07795, and PID:148862; identified by sequence similarity NP_828900.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_828901.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling NP_828902.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins NP_828903.1 identified by match to PFAM protein family HMM PF02639 NP_828904.1 identified by match to PFAM protein family HMM PF04203 NP_828909.1 similar to GB:Z33880, and PID:535939; identified by sequence similarity NP_828910.1 similar to GB:Z33880, and PID:535939; identified by sequence similarity NP_828911.1 identified by match to PFAM protein family HMM PF02563 NP_828912.1 identified by match to PFAM protein family HMM PF01052 NP_828913.1 identified by match to PFAM protein family HMM PF02958 NP_828914.1 identified by match to PFAM protein family HMM PF02484 NP_828915.1 identified by match to PFAM protein family HMM PF04122 NP_828916.1 identified by match to PFAM protein family HMM PF02151 NP_828917.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs NP_828918.1 Catalyzes the phosphorylation of UMP to UDP NP_828919.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu NP_828920.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit NP_828921.1 similar to PIR:A60109; identified by sequence similarity NP_828922.1 similar to GB:S85353, PID:246437, GB:J02938, GB:U13680, GB:X15954, GB:X15957, SP:P07864, PID:187074, PID:307120, and PID:535360; identified by sequence similarity NP_828923.1 similar to GB:D28770, PID:523232, PID:523234, and PID:2335043; identified by sequence similarity NP_828924.1 with SufCD activates cysteine desulfurase SufS NP_828925.1 similar to GB:D28770, PID:523232, PID:523234, and PID:2335043; identified by sequence similarity NP_828926.1 identified by match to PFAM protein family HMM PF01458 NP_828927.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_828928.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_828929.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_828930.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_828931.1 similar to GB:M21161, SP:P13421, and PID:152864; identified by sequence similarity NP_828932.1 identified by match to TIGR protein family HMM TIGR01842 NP_828933.1 similar to GB:M21161, SP:P13421, and PID:152864; identified by sequence similarity NP_828934.1 similar to GB:M21161, SP:P13421, and PID:152864; identified by sequence similarity NP_828935.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway NP_828936.1 similar to GB:M88334, SP:P25526, PID:147901, GB:U00096, PID:1789015, GB:M88334, SP:P25526, PID:147901, GB:U00096, and PID:1789015; identified by sequence similarity NP_828937.1 similar to GB:M88334, SP:P25526, PID:147901, GB:U00096, and PID:1789015; identified by sequence similarity NP_828938.1 similar to GB:M88334, SP:P25526, PID:147901, GB:U00096, and PID:1789015; identified by sequence similarity NP_828939.1 identified by match to TIGR protein family HMM TIGR00563 NP_828941.1 similar to GB:M57961, and PID:149570; identified by sequence similarity NP_828942.1 similar to GB:M57961, and PID:149570; identified by sequence similarity NP_828943.1 identified by match to PFAM protein family HMM PF02518 NP_828944.1 similar to GB:L13940, PID:295432, and SP:P54297; identified by sequence similarity NP_828945.1 similar to GB:L13940, PID:295432, and SP:P54297; identified by sequence similarity NP_828947.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase NP_828948.1 similar to SP:P09836; identified by sequence similarity NP_828950.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG NP_828951.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes NP_828952.1 similar to GB:U08377, and PID:508231; identified by sequence similarity NP_828953.1 similar to GB:X78992, SP:P47974, PID:509778, and PID:984509; identified by sequence similarity NP_828954.1 identified by match to TIGR protein family HMM TIGR00411 NP_828957.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, PID:144977, GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_828958.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, PID:144977, GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_828959.1 3'-5' exonuclease of DNA polymerase III NP_828960.1 similar to GB:L05176, SP:Q02540, and PID:151181; identified by sequence similarity NP_828961.1 Transfers the fatty acyl group on membrane lipoproteins NP_828962.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis NP_828963.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP NP_828964.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis NP_828965.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth NP_828966.1 similar to GB:X57326, and PID:48151; identified by sequence similarity NP_828967.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin NP_828968.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA NP_828969.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel NP_828970.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation NP_828971.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA NP_828972.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center NP_828973.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation NP_828974.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e NP_828975.1 one of the stabilizing components for the large ribosomal subunit NP_828976.1 primary binding protein; helps mediate assembly; involved in translation fidelity NP_828977.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase NP_828978.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel NP_828979.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 NP_828980.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit NP_828981.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance NP_828982.1 binds 5S rRNA along with protein L5 and L25 NP_828983.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance NP_828984.1 late assembly protein NP_828985.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase NP_828986.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA NP_828987.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 NP_828988.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme NP_828989.1 is a component of the macrolide binding site in the peptidyl transferase center NP_828990.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate NP_828991.1 similar to GB:L14017, and PID:295162; identified by sequence similarity NP_828992.1 similar to GB:L14017, and PID:295162; identified by sequence similarity NP_828993.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity NP_828994.1 plays an essential role in ATP-dependent branch migration of the Holliday junction NP_828995.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate NP_828996.1 similar to SP:P32099, GB:X69957, SP:P43148, and PID:396259; identified by sequence similarity NP_828997.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs NP_828998.1 unwinds double stranded DNA NP_828999.1 similar to GB:D21270, and PID:600252; identified by sequence similarity NP_829000.1 similar to GB:D21270, and PID:600252; identified by sequence similarity NP_829001.1 similar to GB:D21270, and PID:600252; identified by sequence similarity NP_829002.1 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair NP_829003.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis NP_829004.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes NP_829005.1 similar to GB:M25260, SP:P26778, and PID:304172; identified by sequence similarity NP_829006.1 catalyzes the formation of orotidine monophosphate from 5-phosphoribosyl-1-pyrophosphate and orotate NP_829007.1 similar to GB:M17643, SP:P10728, PID:143614, PID:1303999, and GB:AL009126; identified by sequence similarity NP_829008.1 identified by match to PFAM protein family HMM PF00149 NP_829009.1 similar to GP:7190800; identified by sequence similarity NP_829010.1 similar to GB:M87483, SP:Q02000, PID:149518, GB:J04088, SP:P11388, and PID:292830; identified by sequence similarity NP_829011.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic NP_829012.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829013.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829016.1 similar to SP:P00808, GB:X05798, and GB:V00093; identified by sequence similarity NP_829017.1 similar to SP:P00808, GB:X05798, and GB:V00093; identified by sequence similarity NP_829018.1 similar to SP:P00808, GB:X05798, and GB:V00093; identified by sequence similarity NP_829019.1 identified by match to PFAM protein family HMM PF01035 NP_829021.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily NP_829022.1 similar to GB:M22916, GB:L10505, SP:P39790, PID:143210, PID:143702, and GB:AL009126; identified by sequence similarity NP_829023.1 identified by match to TIGR protein family HMM TIGR00278 NP_829024.1 similar to GP:7190783, and GP:7190783; identified by sequence similarity NP_829026.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA NP_829028.1 identified by match to PFAM protein family HMM PF02482 NP_829029.1 identified by match to PFAM protein family HMM PF02889 NP_829030.1 identified by match to PFAM protein family HMM PF02486 NP_829031.1 identified by match to PFAM protein family HMM PF02518 NP_829032.1 identified by match to PFAM protein family HMM PF03902 NP_829034.1 identified by match to TIGR protein family HMM TIGR01548 NP_829035.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers NP_829036.1 similar to GB:L10328, SP:P04846, GB:M12163, PID:146649, PID:290510, GB:U00096, PID:1790093, GB:L10328, SP:P04846, GB:M12163, PID:146649, PID:290510, GB:U00096, and PID:1790093; identified by sequence similarity NP_829037.1 similar to GB:L10328, SP:P04846, GB:M12163, PID:146649, PID:290510, GB:U00096, and PID:1790093; identified by sequence similarity NP_829039.1 recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1 NP_829040.1 similar to GB:L25079, SP:P42822, and PID:529423; identified by sequence similarity NP_829041.1 similar to GB:L25079, SP:P42822, PID:529423, GB:L25079, SP:P42822, and PID:529423; identified by sequence similarity NP_829042.1 similar to GP:7190771, and GP:7190771; identified by sequence similarity NP_829043.1 similar to GB:L25079, SP:P42822, and PID:529423; identified by sequence similarity NP_829044.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active NP_829045.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase NP_829046.1 similar to SP:P14916, GB:X17079, PID:149010, PID:43634, PID:1567116, and PID:2313154; identified by sequence similarity NP_829047.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP NP_829048.1 similar to SP:Q9Z7Y6; identified by sequence similarity NP_829049.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate NP_829050.1 similar to SP:Q03523, GB:Z25865, and GB:Z15056; identified by sequence similarity NP_829051.1 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; in these organisms there is an unknown N-terminal domain NP_829052.1 similar to GP:3063673; identified by sequence similarity NP_829053.1 similar to GP:1783378, and GP:1783378; identified by sequence similarity NP_829054.1 similar to SP:P94661, and SP:P94661; identified by sequence similarity NP_829055.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation NP_829056.1 similar to GB:L07795, and PID:148862; identified by sequence similarity NP_829057.1 similar to GB:X79980, and PID:510454; identified by sequence similarity; small CRP; small cysteine-rich protein NP_829058.1 similar to GB:X79980, and PID:510454; identified by sequence similarity; OmcB NP_829059.1 similar to GB:M81087, SP:P41171, and PID:154675; identified by sequence similarity NP_829060.1 identified by match to PFAM protein family HMM PF02692 NP_829063.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance NP_829064.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit NP_829065.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene NP_829066.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex NP_829067.1 similar to SP:P38038; identified by sequence similarity NP_829068.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate NP_829069.1 similar to GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, GB:AL009126, GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, and GB:AL009126; identified by sequence similarity NP_829070.1 identified by match to PFAM protein family HMM PF00829 NP_829071.1 involved in the peptidyltransferase reaction during translation NP_829072.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication NP_829073.1 identified by match to PFAM protein family HMM PF02653 NP_829074.1 identified by match to TIGR protein family HMM TIGR01186 NP_829075.1 identified by match to PFAM protein family HMM PF01297 NP_829076.1 identified by match to PFAM protein family HMM PF02581 NP_829077.1 similar to SP:P76423; identified by sequence similarity NP_829078.1 identified by match to PFAM protein family HMM PF02415 NP_829079.1 similar to GP:8978910; identified by sequence similarity NP_829082.1 similar to GB:M16753, and PID:143529; identified by sequence similarity NP_829083.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis NP_829084.1 identified by match to PFAM protein family HMM PF01258 NP_829085.1 similar to GB:M16753, PID:143529, GB:M16753, and PID:143529; identified by sequence similarity NP_829086.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine NP_829087.1 identified by match to PFAM protein family HMM PF03602 NP_829088.1 identified by match to PFAM protein family HMM PF03236 NP_829089.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate NP_829090.1 identified by match to PFAM protein family HMM PF02447 NP_829091.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA NP_829092.1 identified by match to PFAM protein family HMM PF00571 NP_829093.1 similar to GB:U02462, and PID:407294; identified by sequence similarity NP_829094.1 similar to GP:7189157, and GP:7189157; identified by sequence similarity NP_829095.1 similar to GB:U02462, PID:407294, GB:U02462, and PID:407294; identified by sequence similarity NP_829096.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis NP_829097.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate NP_829098.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_829099.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate NP_829100.1 similar to SP:Q9Z834, GB:U09005, SP:P40608, and PID:507737; identified by sequence similarity NP_829101.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone NP_829102.1 similar to GB:L17309, SP:P39064, PID:348049, PID:2293223, and GB:AL009126; identified by sequence similarity NP_829103.1 identified by match to PFAM protein family HMM PF04055 NP_829104.1 similar to GP:7189168, and GP:7189168; identified by sequence similarity NP_829105.1 similar to GB:L17309, SP:P39064, PID:348049, PID:2293223, and GB:AL009126; identified by sequence similarity NP_829106.1 similar to GB:M63957, SP:P30720, PID:151242, and PID:999193; identified by sequence similarity NP_829107.1 similar to GB:M63957, SP:P30720, PID:151242, and PID:999193; identified by sequence similarity NP_829108.1 similar to GP:8978879, and GP:8978879; identified by sequence similarity NP_829109.1 similar to GP:7190735; identified by sequence similarity NP_829110.1 similar to GP:7190734, GB:X78435, SP:P48226, and PID:468559; identified by sequence similarity NP_829111.1 identified by match to PFAM protein family HMM PF04148 NP_829112.1 similar to GP:8978875, and SP:Q39147; identified by sequence similarity NP_829113.1 identified by match to PFAM protein family HMM PF02672 NP_829114.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria NP_829115.1 similar to GB:M88112, and PID:155306; identified by sequence similarity NP_829116.1 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons NP_829117.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) NP_829118.1 similar to GP:8978869; identified by sequence similarity NP_829119.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, PID:144977, GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_829120.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_829121.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_829122.1 catalyzes the interconversion of tetrahydrodipicolinate and L,L-diaminopimelate in lysine biosynthesis NP_829123.1 identified by match to PFAM protein family HMM PF02987 NP_829126.1 identified by match to PFAM protein family HMM PF02404 NP_829127.1 similar to GP:7189191; identified by sequence similarity NP_829128.1 identified by match to PFAM protein family HMM PF04126 NP_829129.1 similar to GB:X57326, and PID:48151; identified by sequence similarity NP_829131.1 similar to SP:P16256, GB:X57326, and PID:48151; identified by sequence similarity NP_829132.1 similar to GB:X57326, PID:48151, GB:X57326, and PID:48151; identified by sequence similarity NP_829133.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate NP_829134.1 identified by match to PFAM protein family HMM PF02638 NP_829135.1 similar to GP:8978852; identified by sequence similarity NP_829136.1 similar to GB:M99391, and PID:152478; identified by sequence similarity NP_829137.1 identified by match to PFAM protein family HMM PF00753 NP_829138.1 similar to GP:7190694; identified by sequence similarity NP_829139.1 similar to GP:8978847; identified by sequence similarity NP_829140.1 identified by match to PFAM protein family HMM PF02814 NP_829141.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain NP_829142.1 similar to GB:X75069, SP:P41028, and PID:414099; identified by sequence similarity NP_829143.1 identified by match to PFAM protein family HMM PF03421 NP_829144.1 identified by match to PFAM protein family HMM PF02415 NP_829145.1 similar to GB:M19395, SP:P10655, GB:M28336, PID:143130, and PID:143134; identified by sequence similarity NP_829146.1 similar to GB:M19395, SP:P10655, GB:M28336, PID:143130, PID:143134, GB:X75069, SP:P41028, and PID:414099; identified by sequence similarity NP_829147.1 similar to GB:M19395, SP:P10655, GB:M28336, PID:143130, and PID:143134; identified by sequence similarity NP_829148.1 similar to GB:M19395, SP:P10655, GB:M28336, PID:143130, and PID:143134; identified by sequence similarity NP_829150.1 similar to GB:X69957, SP:P43148, and PID:396259; identified by sequence similarity NP_829151.1 identified by match to PFAM protein family HMM PF02415 NP_829152.1 similar to GB:M25260, SP:P26778, and PID:304172; identified by sequence similarity NP_829153.1 similar to GB:S70840, and PID:546752; identified by sequence similarity NP_829154.1 similar to GB:S70840, and PID:546752; identified by sequence similarity NP_829155.1 similar to GB:L09228, SP:P17616, GB:X51510, PID:40084, PID:410123, and GB:AL009126; identified by sequence similarity NP_829156.1 identified by match to PFAM protein family HMM PF02415 NP_829157.1 similar to GB:S70840, PID:546752, GB:L09228, SP:P17616, GB:X51510, PID:40084, PID:410123, and GB:AL009126; identified by sequence similarity NP_829158.1 identified by match to PFAM protein family HMM PF04070 NP_829159.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain NP_829160.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA NP_829161.1 similar to GB:M17643, SP:P10728, PID:143614, PID:1303999, and GB:AL009126; identified by sequence similarity NP_829162.1 similar to GP:8978814; identified by sequence similarity NP_829163.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829164.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids NP_829167.1 similar to GB:M88112, PID:155306, GB:M88112, and PID:155306; identified by sequence similarity NP_829168.1 similar to GB:M88112, PID:155306, GB:M88112, and PID:155306; identified by sequence similarity NP_829169.1 similar to GB:M88112, PID:155306, GB:M88112, and PID:155306; identified by sequence similarity NP_829170.1 similar to GB:M88112, PID:155306, GB:M88112, and PID:155306; identified by sequence similarity NP_829171.1 similar to GB:M88112, PID:155306, GB:M88112, and PID:155306; identified by sequence similarity NP_829172.1 similar to GB:D14607, PID:540502, GB:D14607, and PID:540502; identified by sequence similarity NP_829173.1 similar to GB:D14607, and PID:540502; identified by sequence similarity NP_829174.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin NP_829175.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate NP_829176.1 similar to GB:U14003, SP:P39303, PID:537036, GB:U00096, and PID:2367359; identified by sequence similarity NP_829177.1 catalyzes the bidirectional exonucleolytic cleavage of DNA NP_829178.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides NP_829179.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate NP_829180.1 similar to GB:M33815, SP:P21408, and PID:152860; identified by sequence similarity NP_829182.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) NP_829183.1 identified by match to PFAM protein family HMM PF03859 NP_829184.1 similar to GB:X75568; identified by sequence similarity NP_829185.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell NP_829186.1 identified by match to PFAM protein family HMM PF02483 NP_829187.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_829188.1 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions NP_829190.1 identified by match to PFAM protein family HMM PF02414 NP_829192.1 similar to GP:7190660; identified by sequence similarity NP_829193.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA NP_829194.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion NP_829195.1 identified by match to PFAM protein family HMM PF02745 NP_829196.1 similar to GP:7189658, and GP:7189658; identified by sequence similarity NP_829197.1 similar to SP:P00800, GB:X76986, PID:441267, PID:512558, SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829198.1 similar to SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829199.1 similar to SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829200.1 similar to SP:P00800, GB:X76986, PID:441267, PID:512558, SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829201.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA NP_829203.1 similar to GB:M82881, SP:P33385, PID:149647, GB:M82881, SP:P33385, and PID:149647; identified by sequence similarity NP_829204.1 identified by match to PFAM protein family HMM PF03675 NP_829205.1 similar to GB:M82881, SP:P33385, PID:149647, GB:M82881, SP:P33385, and PID:149647; identified by sequence similarity NP_829207.1 identified by match to PFAM protein family HMM PF03132 NP_829209.1 identified by match to PFAM protein family HMM PF04276 NP_829210.1 transformation of prophobilinogen to hydroxymethylbilane in porphyrin biosynthesis NP_829211.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents NP_829212.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity NP_829213.1 similar to GB:L01055, SP:P31715, GB:S65052, PID:295156, and PID:410007; identified by sequence similarity NP_829214.1 similar to GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829215.1 similar to GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829216.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits NP_829217.1 catalyzes the formation of dUMP from dUTP NP_829218.1 similar to GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829219.1 identified by match to TIGR protein family HMM TIGR01764 NP_829220.1 similar to GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, and GB:AL009126; identified by sequence similarity NP_829221.1 identified by match to PFAM protein family HMM PF02683 NP_829222.1 similar to GB:M87483, SP:Q02000, PID:149518, GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829223.1 similar to GB:D10483, SP:P31553, GB:X73904, PID:216465, PID:563861, GB:U00096, PID:1786224, GB:D10483, SP:P31553, GB:X73904, PID:216465, PID:563861, GB:U00096, and PID:1786224; identified by sequence similarity NP_829224.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs NP_829225.1 similar to GP:7189244; identified by sequence similarity NP_829226.1 similar to GB:D10483, SP:P31553, GB:X73904, PID:216465, PID:563861, GB:U00096, PID:1786224, GB:D10483, SP:P31553, GB:X73904, PID:216465, PID:563861, GB:U00096, and PID:1786224; identified by sequence similarity NP_829227.1 similar to GP:7190598; identified by sequence similarity NP_829228.1 similar to GP:8163246; identified by sequence similarity NP_829229.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor NP_829230.1 identified by match to PFAM protein family HMM PF03248 NP_829231.1 identified by match to PFAM protein family HMM PF03376 NP_829232.1 similar to SP:Q56589; identified by sequence similarity NP_829233.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm NP_829234.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm NP_829235.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm NP_829236.1 similar to GB:Z34287, SP:P39781, PID:498813, and GB:AL009126; identified by sequence similarity NP_829237.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_829239.1 similar to GP:8163245; identified by sequence similarity NP_829240.1 similar to GB:M97296, SP:Q03417, and PID:155583; identified by sequence similarity NP_829241.1 identified by match to PFAM protein family HMM PF03109 NP_829242.1 similar to GP:7190583; identified by sequence similarity NP_829243.1 similar to GB:M83673, and PID:151093; identified by sequence similarity NP_829244.1 similar to GB:S61968, GB:X76688, SP:P46738, GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829245.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate NP_829246.1 similar to GB:M37202, SP:P37716, and PID:141733; identified by sequence similarity NP_829247.1 identified by match to TIGR protein family HMM TIGR00987 NP_829248.1 similar to GB:M37202, SP:P37716, and PID:141733; identified by sequence similarity NP_829249.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein NP_829250.1 similar to GB:M37202, SP:P37716, and PID:141733; identified by sequence similarity NP_829251.1 similar to GB:M90761, SP:Q02137, and PID:149432; identified by sequence similarity NP_829252.1 similar to GB:U09530, GB:Z35104, SP:P46359, PID:493076, and PID:510936; identified by sequence similarity NP_829253.1 3'-5' exonuclease of DNA polymerase III NP_829254.1 similar to GB:Z35107, and PID:510938; identified by sequence similarity NP_829255.1 similar to GB:Z35107, and PID:510938; identified by sequence similarity NP_829256.1 similar to GB:Z35107, and PID:510938; identified by sequence similarity NP_829257.1 Catalyzes a key regulatory step in fatty acid biosynthesis NP_829258.1 similar to GP:7190422, GB:M64978, and PID:150554; identified by sequence similarity NP_829259.1 identified by match to PFAM protein family HMM PF02952 NP_829260.1 similar to GB:Z29675, GB:Z35485, GB:Z35486, GB:Z35487, GB:Z35496, SP:P46360, PID:474835, PID:517232, PID:517234, PID:517236, and PID:517386; identified by sequence similarity NP_829261.1 similar to GB:Z29675, GB:Z35485, GB:Z35486, GB:Z35487, GB:Z35496, SP:P46360, PID:474835, PID:517232, PID:517234, PID:517236, and PID:517386; identified by sequence similarity NP_829262.1 similar to GB:Z29675, GB:Z35485, GB:Z35486, GB:Z35487, GB:Z35496, SP:P46360, PID:474835, PID:517232, PID:517234, PID:517236, and PID:517386; identified by sequence similarity NP_829263.1 similar to GB:L07795, and PID:148862; identified by sequence similarity NP_829264.1 similar to GP:7190581; identified by sequence similarity NP_829265.1 identified by match to PFAM protein family HMM PF04143 NP_829266.1 identified by match to PFAM protein family HMM PF04143 NP_829267.1 similar to GP:8978769; identified by sequence similarity NP_829268.1 similar to GB:L07795, and PID:148862; identified by sequence similarity NP_829269.1 identified by match to PFAM protein family HMM PF03471 NP_829270.1 similar to GP:8978766; identified by sequence similarity NP_829271.1 identified by match to PFAM protein family HMM PF01713 NP_829272.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis NP_829274.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration NP_829276.1 identified by match to PFAM protein family HMM PF02922 NP_829278.1 binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA NP_829279.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides NP_829280.1 similar to GB:Z33880, and PID:535939; identified by sequence similarity NP_829281.1 similar to GB:Z33880, and PID:535939; identified by sequence similarity NP_829282.1 similar to GP:7190360; identified by sequence similarity NP_829284.1 similar to GP:7190361, and GP:7190361; identified by sequence similarity NP_829285.1 identified by match to PFAM protein family HMM PF03634 NP_829286.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_829288.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide NP_829289.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA NP_829290.1 similar to GB:M16753, PID:143529, GB:M16753, and PID:143529; identified by sequence similarity NP_829291.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-clclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; these proteins appear to consist of duplicate domains as compared to Escherichia coli IspG NP_829294.1 identified by match to PFAM protein family HMM PF01661 NP_829295.1 similar to GB:U02462, and PID:407294; identified by sequence similarity NP_829296.1 similar to GB:U02462, and PID:407294; identified by sequence similarity NP_829297.1 expressed in response to temperature increase; may be involved in expression of genes involved in the developmental cycle of Chlamydia NP_829299.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) NP_829300.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate NP_829301.1 binds to the ribosome on the universally-conserved alpha-sarcin loop NP_829302.1 similar to GP:7189329, and GP:7189329; identified by sequence similarity NP_829303.1 similar to GP:7190377; identified by sequence similarity NP_829305.1 similar to GB:M63957, SP:P30720, PID:151242, and PID:999193; identified by sequence similarity NP_829306.1 identified by match to TIGR protein family HMM TIGR01662 NP_829307.1 identified by match to PFAM protein family HMM PF02653 NP_829308.1 similar to GB:X78435, SP:P48226, and PID:468559; identified by sequence similarity NP_829309.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate NP_829310.1 similar to GB:X78435, SP:P48226, and PID:468559; identified by sequence similarity NP_829311.1 identified by match to PFAM protein family HMM PF02684 NP_829312.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA NP_829313.1 binds the polymerase to DNA and acts as a sliding clamp NP_829314.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation NP_829315.1 identified by match to PFAM protein family HMM PF02424 NP_829316.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate NP_829317.1 similar to GP:7190393; identified by sequence similarity NP_829318.1 similar to GB:U14003, SP:P39303, PID:537036, GB:U00096, PID:2367359, GB:U14003, SP:P39303, PID:537036, GB:U00096, and PID:2367359; identified by sequence similarity NP_829319.1 similar to GB:U14003, SP:P39303, PID:537036, GB:U00096, and PID:2367359; identified by sequence similarity NP_829321.1 similar to GP:2444077; identified by sequence similarity NP_829322.1 similar to SP:O34023, GB:D14607, and PID:540502; identified by sequence similarity NP_829323.1 required for 70S ribosome assembly NP_829324.1 amylomaltase; acts to release glucose from maltodextrins NP_829325.1 similar to GP:2444074; identified by sequence similarity NP_829326.1 similar to GB:M63957, SP:P30718, GB:U17072, PID:151243, PID:999194, GB:M63957, SP:P30718, GB:U17072, PID:151243, and PID:999194; identified by sequence similarity NP_829327.1 similar to GB:L27528, SP:P38098, PID:440837, PID:451651, and PID:1750385; identified by sequence similarity NP_829328.1 identified by match to PFAM protein family HMM PF02695 NP_829329.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 NP_829330.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities NP_829331.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock NP_829332.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex NP_829333.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination NP_829334.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins NP_829335.1 similar to GB:L19685, and PID:404771; identified by sequence similarity NP_829336.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids NP_829337.1 similar to SP:P11895, GB:M35124, SP:P16077, GB:X05813, GB:X13521, PID:14584, PID:147886, PID:148608, PID:42375, PID:42645, SP:P11895, GB:M35124, SP:P16077, GB:X05813, GB:X13521, PID:14584, PID:147886, PID:148608, PID:42375, and PID:42645; identified by sequence similarity NP_829338.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein NP_829339.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria NP_829340.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. NP_829341.1 identified by match to PFAM protein family HMM PF03376 NP_829342.1 similar to GB:M17642, SP:P11469, PID:142968, and GB:AL009126; identified by sequence similarity NP_829343.1 Catalyzes the transfer of acetyl from acetyldihydrolipoamide to coenzyme A to form acetyl CoA NP_829344.1 similar to GB:M17642, SP:P11469, PID:142968, and GB:AL009126; identified by sequence similarity NP_829345.1 similar to GB:M17642, SP:P11469, PID:142968, and GB:AL009126; identified by sequence similarity NP_829346.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis NP_829347.1 identified by match to PFAM protein family HMM PF04102 NP_829348.1 identified by match to PFAM protein family HMM PF03072 NP_829349.1 involved in a recombinational process of DNA repair, independent of the recBC complex NP_829350.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs NP_829351.1 identified by match to PFAM protein family HMM PF03861 NP_829352.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis NP_829353.1 carries the fatty acid chain in fatty acid biosynthesis NP_829354.1 similar to GB:X69957, SP:P43148, and PID:396259; identified by sequence similarity NP_829355.1 similar to GB:X69957, SP:P43148, and PID:396259; identified by sequence similarity NP_829356.1 similar to GB:D10208, SP:P49250, PID:216723, GB:D10208, SP:P49250, and PID:216723; identified by sequence similarity NP_829357.1 similar to GB:D10208, SP:P49250, PID:216723, GB:D10208, SP:P49250, and PID:216723; identified by sequence similarity NP_829358.1 similar to GB:D21270, and PID:600252; identified by sequence similarity NP_829359.1 similar to GB:M88104, SP:P28617, PID:142447, GB:M88104, SP:P28617, and PID:142447; identified by sequence similarity NP_829360.1 similar to GB:M25260, SP:P26778, and PID:304172; identified by sequence similarity NP_829361.1 similar to GB:M25260, SP:P26778, PID:304172, GB:M25260, SP:P26778, and PID:304172; identified by sequence similarity NP_829362.1 identified by match to PFAM protein family HMM PF02466 NP_829363.1 similar to GB:M25260, SP:P26778, PID:304172, GB:M25260, SP:P26778, and PID:304172; identified by sequence similarity NP_829364.1 similar to GB:M17643, SP:P10728, PID:143614, PID:1303999, and GB:AL009126; identified by sequence similarity NP_829365.1 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate NP_829366.1 similar to GP:7190527, and GP:7190527; identified by sequence similarity NP_829367.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829368.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829369.1 similar to GB:M87483, SP:Q02000, and PID:149518; identified by sequence similarity NP_829371.1 similar to GB:D10483, SP:P31553, GB:X73904, PID:216465, PID:563861, GB:U00096, and PID:1786224; identified by sequence similarity NP_829372.1 negatively supercoils closed circular double-stranded DNA NP_829373.1 negatively supercoils closed circular double-stranded DNA NP_829374.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) NP_829375.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA NP_829376.1 identified by match to PFAM protein family HMM PF02230 NP_829377.1 identified by match to PFAM protein family HMM PF01300 NP_829378.1 similar to GB:L06332, SP:P36913, and PID:148696; identified by sequence similarity NP_829379.1 similar to SP:P35579; identified by sequence similarity NP_829380.1 identified by match to PFAM protein family HMM PF03334 NP_829381.1 UbiA prenyltransferase catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin NP_829382.1 similar to SP:P33751; identified by sequence similarity NP_829383.1 similar to GB:Z34287, SP:P39781, PID:498813, and GB:AL009126; identified by sequence similarity NP_829384.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate NP_829385.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate NP_829386.1 similar to GB:M97296, SP:Q03417, PID:155583, GB:M97296, SP:Q03417, and PID:155583; identified by sequence similarity NP_829387.1 identified by match to PFAM protein family HMM PF02810 NP_829388.1 similar to GB:M83673, and PID:151093; identified by sequence similarity NP_829389.1 similar to GB:M58563, SP:P29720, PID:155067, GB:M58563, SP:P29720, and PID:155067; identified by sequence similarity NP_829390.1 similar to GB:M83673, and PID:151093; identified by sequence similarity NP_829391.1 identified by match to PFAM protein family HMM PF04055 NP_829392.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif NP_829393.1 similar to GB:U09530, GB:Z35104, SP:P46359, PID:493076, and PID:510936; identified by sequence similarity NP_829394.1 similar to GB:U09530, GB:Z35104, SP:P46359, PID:493076, and PID:510936; identified by sequence similarity NP_829395.1 identified by match to PFAM protein family HMM PF02673 NP_829397.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit NP_829398.1 forms a direct contact with the tRNA during translation NP_829399.1 similar to GB:Z35107, and PID:510938; identified by sequence similarity NP_829400.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP NP_829401.1 identified by match to PFAM protein family HMM PF02673 NP_829402.1 similar to GB:Z35105, GB:Z35106, GB:Z38064, GB:Z38065, PID:510890, PID:510892, PID:557752, and PID:557754; identified by sequence similarity NP_829403.1 similar to GP:8978614, and GP:8978614; identified by sequence similarity NP_829404.1 catalyzes the formation of 6-phospho-D-gluconate from 6-phospho-D-glucono-1,5-lactone NP_829405.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate NP_829406.1 similar to GB:U09005, SP:P40608, and PID:507737; identified by sequence similarity NP_829407.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity NP_829408.1 similar to GB:U09005, SP:P40608, and PID:507737; identified by sequence similarity NP_829409.1 similar to GP:8978565; identified by sequence similarity NP_829410.1 similar to GB:L17309, SP:P39064, PID:348049, PID:2293223, and GB:AL009126; identified by sequence similarity NP_829411.1 similar to GB:L17309, SP:P39064, PID:348049, PID:2293223, GB:AL009126, GB:L17309, SP:P39064, PID:348049, PID:2293223, and GB:AL009126; identified by sequence similarity NP_829412.1 similar to GP:7189490, and GP:7189490; identified by sequence similarity NP_829413.1 similar to GB:M63957, SP:P30720, PID:151242, PID:999193, GB:M63957, SP:P30720, PID:151242, and PID:999193; identified by sequence similarity NP_829414.1 similar to GP:5139640, GB:M14777, GB:S76221, GB:S76223, GB:S76225, GB:S76228, GB:S76232, GB:S76235, GB:S49975, GB:M21866, GB:M21758, GB:M15872, GB:M25627, GB:S76219, SP:P08263, SP:P09210, PID:187132, PID:306809, PID:306810, PID:306815, PID:825605, and PID:951352; identified by sequence similarity NP_829415.1 similar to GB:M28668, GB:M55131, GB:M55106, GB:M55107, GB:M55108, GB:M55109, GB:M55110, GB:M55111, GB:M55112, GB:M55113, GB:M55114, GB:M55115, GB:M55116, GB:M55117, GB:M55118, GB:M55119, GB:M55120, GB:M55121, GB:M55122, GB:M55123, GB:M55124, GB:M55125, GB:M55126, GB:M55127, GB:M55128, GB:M55129, GB:M55130, GB:X53294, GB:M55025, GB:M55026, GB:M55027, GB:M55028, GB:M55029, GB:M55030, GB:M55031, GB:M55032, GB:M55033, GB:M55034, GB:M55035, GB:M55036, GB:M55037, GB:M57509, GB:M65196, GB:M65197, GB:M65198, GB:M65273, GB:M65274, GB:M65276, GB:M65277, GB:M65278, GB:M65279, GB:M65280, GB:M65281, GB:M65282, GB:M65283, GB:M65284, GB:M65285, GB:M65286, GB:M65288, GB:M58478, GB:M26383, GB:D14283, GB:Z11686, GB:Y00787, SP:P13569, PID:1100104, PID:1669377, PID:1669378, PID:180292, PID:180332, PID:1809238, PID:306538, PID:553225, GB:M28668, GB:M55131, GB:M55106, GB:M55107, GB:M55108, GB:M55109, GB:M55110, GB:M55111, GB:M55112, GB:M55113, GB:M55114, GB:M55115, GB:M55116, GB:M55117, GB:M55118, GB:M55119, GB:M55120, GB:M55121 NP_829416.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate NP_829417.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_829418.1 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_829419.1 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism NP_829421.1 identified by match to PFAM protein family HMM PF02686 NP_829422.1 identified by match to PFAM protein family HMM PF03334 NP_829423.1 This protein has a UDP-glucose binding domain and a glycosyltransferase domain. See PMID: 9677381 and PMID: 10788427.; similar to GP:7190483; identified by sequence similarity NP_829424.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_829425.1 similar to GB:X73124, SP:P39577, PID:413925, GB:AL009126, GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829426.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription NP_829427.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate NP_829428.1 similar to GP:5579054; identified by sequence similarity NP_829429.1 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis NP_829430.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate NP_829431.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis NP_829432.1 similar to GB:L04569, GB:M57971, GB:Z34811, GB:Z34812, GB:Z34821, GB:Z34822, GB:Z34809, GB:Z34810, GB:Z34813, GB:Z34814, GB:Z34815, GB:Z34816, GB:Z34817, GB:Z34818, GB:Z34819, GB:Z34820, GB:M57972, GB:M91370, GB:Z26294, GB:Z26295, PID:291895, PID:501073, PID:508183, PID:508185, PID:508187, PID:508189, PID:508191, PID:508193, PID:508195, PID:508197, PID:508199, PID:508201, PID:509048, PID:509068, PID:509168, PID:509178, PID:509341, PID:509344, GB:L04569, GB:M57971, GB:Z34811, GB:Z34812, GB:Z34821, GB:Z34822, GB:Z34809, GB:Z34810, GB:Z34813, GB:Z34814, GB:Z34815, GB:Z34816, GB:Z34817, GB:Z34818, GB:Z34819, GB:Z34820, GB:M57972, GB:M91370, GB:Z26294, GB:Z26295, PID:291895, PID:501073, PID:508183, PID:508185, PID:508187, PID:508189, PID:508191, PID:508193, PID:508195, PID:508197, PID:508199, PID:508201, PID:509048, PID:509068, PID:509168, PID:509178, PID:509341, and PID:509344; identified by sequence similarity NP_829433.1 similar to GP:6968355, and SP:P08330; identified by sequence similarity NP_829436.1 similar to GP:7190486; identified by sequence similarity NP_829437.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway NP_829438.1 similar to GP:7190488, GB:U10906, SP:P46527, and PID:516559; identified by sequence similarity NP_829440.1 similar to GP:7189507; identified by sequence similarity NP_829443.1 similar to GB:S61968, GB:X76688, SP:P46738, GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829444.1 similar to GB:L01055, SP:P31715, GB:S65052, PID:295156, and PID:410007; identified by sequence similarity NP_829445.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4, 5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7- deazaguanosine) NP_829446.1 similar to GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, GB:AL009126, GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, and GB:AL009126; identified by sequence similarity NP_829447.1 similar to GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, GB:AL009126, GB:X05678, SP:P07788, GB:X07512, PID:39855, PID:39857, PID:1708638, and GB:AL009126; identified by sequence similarity NP_829448.1 identified by match to PFAM protein family HMM PF00541 NP_829450.1 similar to GB:S61968, GB:X76688, SP:P46738, GB:S61968, GB:X76688, and SP:P46738; identified by sequence similarity NP_829451.1 similar to GB:Z28353, and PID:431949; identified by sequence similarity NP_829452.1 similar to GB:X73124, SP:P39577, PID:413925, GB:AL009126, GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829454.1 identified by match to PFAM protein family HMM PF02497 NP_829455.1 similar to GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829456.1 similar to GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829457.1 similar to GB:X73124, SP:P39577, PID:413925, GB:AL009126, GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829459.1 similar to GB:M68877, and PID:152867; identified by sequence similarity NP_829460.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS NP_829461.1 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer NP_829462.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function NP_829463.1 similar to SP:P24141, GB:L24960, and PID:407009; identified by sequence similarity NP_829464.1 similar to SP:P24141; identified by sequence similarity NP_829465.1 similar to SP:P24141, GB:Z28353, and PID:431949; identified by sequence similarity NP_829466.1 similar to GP:8978572; identified by sequence similarity NP_829467.1 similar to SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829468.1 similar to SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829469.1 similar to SP:P00800, GB:X76986, PID:441267, and PID:512558; identified by sequence similarity NP_829470.1 similar to GB:M37842, SP:P11000, and PID:153858; identified by sequence similarity NP_829471.1 similar to GP:8978580; identified by sequence similarity NP_829472.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate NP_829473.1 similar to GB:X78729, SP:P45600, and PID:511012; identified by sequence similarity NP_829474.1 catalyzes the formation of fructose 1,6-bisphosphate from fructose 6-phosphate and diphosphate NP_829475.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A NP_829476.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase NP_829478.1 similar to SP:P11895, GB:M35124, SP:P16077, GB:X05813, GB:X13521, PID:14584, PID:147886, PID:148608, PID:42375, and PID:42645; identified by sequence similarity NP_829479.1 similar to SP:P11895, GB:M35124, SP:P16077, GB:X05813, GB:X13521, PID:14584, PID:147886, PID:148608, PID:42375, PID:42645, SP:P11895, GB:M35124, SP:P16077, GB:X05813, GB:X13521, PID:14584, PID:147886, PID:148608, PID:42375, and PID:42645; identified by sequence similarity NP_829480.1 identified by match to TIGR protein family HMM TIGR01870 NP_829481.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB NP_829482.1 similar to GP:7189538; identified by sequence similarity NP_829483.1 similar to GB:D38405, PID:551625, SP:Q59536, GB:D38405, PID:551625, and SP:Q59536; identified by sequence similarity NP_829484.1 similar to GB:D38405, PID:551625, and SP:Q59536; identified by sequence similarity NP_829485.1 similar to GB:D38405, PID:551625, SP:Q59536, GB:D38405, PID:551625, and SP:Q59536; identified by sequence similarity NP_829486.1 identified by match to PFAM protein family HMM PF03334 NP_829487.1 similar to GB:D38405, PID:551625, and SP:Q59536; identified by sequence similarity NP_829488.1 similar to GB:L09228, SP:P17616, GB:X51510, PID:40084, PID:410123, and GB:AL009126; identified by sequence similarity NP_829489.1 identified by match to PFAM protein family HMM PF02381 NP_829490.1 identified by match to PFAM protein family HMM PF02470 NP_829491.1 similar to GB:Z12296, and PID:43338; identified by sequence similarity NP_829492.1 similar to GB:Z12296, PID:43338, GB:Z12296, and PID:43338; identified by sequence similarity NP_829493.1 catalyzes the formation of 5-aminolevulinate from (S)-4-amino-5-oxopentanoate NP_829494.1 identified by match to PFAM protein family HMM PF02622 NP_829495.1 similar to GB:M99391, and PID:152478; identified by sequence similarity NP_829496.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway NP_829497.1 identified by match to PFAM protein family HMM PF03334 NP_829500.1 similar to GP:7189329; identified by sequence similarity NP_829503.1 similar to GB:L17309, SP:P39064, PID:348049, PID:2293223, GB:AL009126, GB:L17309, SP:P39064, PID:348049, PID:2293223, and GB:AL009126; identified by sequence similarity NP_829504.1 identified by match to TIGR protein family HMM TIGR00486 NP_829505.1 identified by match to PFAM protein family HMM PF04063 NP_829506.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring NP_829507.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth NP_829508.1 similar to GB:U11013, PID:506777, and SP:P50927; identified by sequence similarity NP_829509.1 identified by match to PFAM protein family HMM PF03083 NP_829511.1 similar to GP:8978503; identified by sequence similarity NP_829513.1 similar to GB:L34167, PID:508600, GB:L34167, and PID:508600; identified by sequence similarity NP_829514.1 similar to GB:U11017, PID:506782, and SP:P50929; identified by sequence similarity NP_829515.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content NP_829516.1 similar to GB:U11017, PID:506782, and SP:P50929; identified by sequence similarity NP_829517.1 Essential for recycling GMP and indirectly, cGMP NP_829518.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids NP_829519.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site NP_829520.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; Chlamydial proteins show a C-terminal extension of unknown function NP_829521.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity NP_829522.1 similar to GB:U11020, PID:506786, and SP:P50931; identified by sequence similarity NP_829523.1 HemK; PrmC; transfers a methyl group from S-adenosyl-methionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB possibly stimulating release of completed polypeptide chains NP_829524.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 NP_829525.1 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome NP_829527.1 similar to SP:P07024, GB:X03895, PID:1773162, and PID:1786687; identified by sequence similarity NP_829528.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) NP_829529.1 similar to GB:L04979, SP:P28307, PID:290425, PID:1147564, GB:U00096, PID:1651511, PID:1651514, and PID:1787279; identified by sequence similarity NP_829530.1 identified by match to PFAM protein family HMM PF02562 NP_829532.1 similar to GB:L04979, SP:P28307, PID:290425, PID:1147564, GB:U00096, PID:1651511, PID:1651514, and PID:1787279; identified by sequence similarity NP_829533.1 identified by match to PFAM protein family HMM PF02652 NP_829534.1 similar to GB:L04979, SP:P28307, PID:290425, PID:1147564, GB:U00096, PID:1651511, PID:1651514, and PID:1787279; identified by sequence similarity NP_829535.1 identified by match to PFAM protein family HMM PF02457 NP_829536.1 similar to GP:7189588; identified by sequence similarity NP_829537.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA NP_829539.1 catalyzes the formation of phosphoenolpyruvate from pyruvate NP_829540.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate NP_829541.1 PknD; responsible for phosphorylation of proteins on serine and threonine residues; similar to eukaryotic Ser/Thr kinases; in Chlamydia trachomatis itseems to interact with Pkn1, another serine/threonine-protein kinase NP_829542.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain NP_829544.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits NP_829545.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel. NP_829546.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex NP_829547.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex NP_829548.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex NP_829549.1 similar to GP:7190621; identified by sequence similarity NP_829550.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the E subunit is part of the catalytic core of the ATP synthase complex NP_829551.1 similar to GB:Z35107, and PID:510938; identified by sequence similarity NP_829552.1 similar to GB:Z35107, PID:510938, GB:Z35107, and PID:510938; identified by sequence similarity NP_829553.1 Maintains the balance of metabolites in the pentose-phosphate pathway NP_829554.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter NP_829555.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme NP_829556.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors NP_829557.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit NP_829558.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA NP_829559.1 binds directly to 23S ribosomal RNA NP_829560.1 Modulates Rho-dependent transcription termination NP_829561.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force NP_829562.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu NP_829563.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 NP_829564.1 identified by match to PFAM protein family HMM PF02517 NP_829565.1 similar to GP:7189619; identified by sequence similarity NP_829566.1 similar to GP:1236759; identified by sequence similarity NP_829570.1 similar to GB:L19895, SP:P43877, PID:469174, GB:L19895, SP:P43877, and PID:469174; identified by sequence similarity NP_829571.1 identified by match to PFAM protein family HMM PF02984 NP_829572.1 identified by match to PFAM protein family HMM PF03025 NP_829573.1 similar to GB:X73124, SP:P39577, PID:413925, GB:AL009126, GB:X73124, SP:P39577, PID:413925, and GB:AL009126; identified by sequence similarity NP_829574.1 similar to GB:L25276, SP:P35641, PID:408488, GB:L25276, SP:P35641, and PID:408488; identified by sequence similarity NP_829576.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis NP_829577.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP NP_829578.1 catalyzes the formation of aspartate semialdehyde from aspartyl phosphate NP_829579.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis NP_829580.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin NP_829581.1 identified by match to PFAM protein family HMM PF02592 NP_829582.1 similar to GP:7190297, and GP:7190297; identified by sequence similarity NP_829583.1 similar to GP:6117874; identified by sequence similarity NP_829584.1 A segment of this protein has high similarity to a Chlamydia phage protein.; similar to GP:7406593, and GP:7406593; identified by sequence similarity NP_829585.1 This protein contains two segments highly homologous to Chlamydia phage proteins.; similar to GP:7406595, GP:7406595, and GP:7406589; identified by sequence similarity NP_829586.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis NP_829587.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis NP_829588.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis NP_829589.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis NP_829590.1 AroDE; bifunctional enzyme; can convert 3-dehydroquinate to 3-dehydroshkimate and then to shikimate; involved in the synthesis of aromatic amino acids and other metabolites; type I 3-DHQase NP_829591.1 similar to GB:M17642, SP:P11469, PID:142968, and GB:AL009126; identified by sequence similarity NP_829592.1 identified by match to PFAM protein family HMM PF00089 NP_829593.1 similar to GB:M99391, and PID:152478; identified by sequence similarity NP_829594.1 similar to GP:8163506; identified by sequence similarity NP_829595.1 identified by match to PFAM protein family HMM PF01266 NP_829596.1 identified by match to PFAM protein family HMM PF02588 NP_829597.1 catalyzes the oxidation of malate to oxaloacetate NP_829598.1 similar to GB:U11013, PID:506777, and SP:P50927; identified by sequence similarity NP_829599.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family NP_829600.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs NP_829601.1 similar to GB:U11013, PID:506777, SP:P50927, GB:U11013, PID:506777, and SP:P50927; identified by sequence similarity NP_829602.1 similar to GB:U11013, PID:506777, and SP:P50927; identified by sequence similarity NP_829603.1 similar to GB:M74042, PID:454843, and SP:P50928; identified by sequence similarity NP_829604.1 similar to GB:M74042, PID:454843, and SP:P50928; identified by sequence similarity NP_829605.1 similar to GB:M74042, PID:454843, and SP:P50928; identified by sequence similarity NP_829606.1 similar to GB:M74042, PID:454843, SP:P50928, GB:M74042, PID:454843, and SP:P50928; identified by sequence similarity NP_829607.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway NP_829608.1 similar to GB:M74042, PID:454843, and SP:P50928; identified by sequence similarity NP_829609.1 identified by match to PFAM protein family HMM PF02447 NP_829610.1 similar to GB:U11017, PID:506782, and SP:P50929; identified by sequence similarity NP_829611.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle NP_829612.1 similar to GB:U11017, PID:506782, and SP:P50929; identified by sequence similarity NP_829613.1 similar to GP:7190282; identified by sequence similarity NP_829614.1 similar to GB:U11020, PID:506786, SP:P50931, GB:U11020, PID:506786, and SP:P50931; identified by sequence similarity NP_829615.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides NP_829616.1 similar to GB:U11020, PID:506786, and SP:P50931; identified by sequence similarity NP_829617.1 similar to GB:U11020, PID:506786, and SP:P50931; identified by sequence similarity NP_829618.1 similar to SP:P07024, GB:X03895, PID:1773162, and PID:1786687; identified by sequence similarity NP_829620.1 similar to SP:P07024, GB:X03895, PID:1773162, and PID:1786687; identified by sequence similarity NP_829621.1 similar to SP:P07024, GB:X03895, PID:1773162, and PID:1786687; identified by sequence similarity NP_829622.1 similar to GP:8979375; identified by sequence similarity NP_829623.1 identified by match to PFAM protein family HMM PF00383 NP_829624.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence NP_829625.1 identified by match to PFAM protein family HMM PF02548 NP_829626.1 identified by match to PFAM protein family HMM PF02642 NP_829627.1 identified by match to PFAM protein family HMM PF02629 NP_829628.1 similar to SP:P13979, GB:X52553, SP:P15177, SP:P32885, and GB:J01769; identified by sequence similarity NP_829629.1 similar to SP:P13979, GB:X52553, SP:P15177, SP:P32885, and GB:J01769; identified by sequence similarity NP_829630.1 similar to SP:P13979, GB:X52553, SP:P15177, SP:P32885, and GB:J01769; identified by sequence similarity NP_829631.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily NP_829632.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit NP_829633.1 identified by match to PFAM protein family HMM PF01632 NP_829634.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits NP_829635.1 Regulates rRNA biosynthesis by transcriptional antitermination NP_829636.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis NP_829637.1 similar to GP:7190256; identified by sequence similarity NP_829638.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine NP_829639.1 Catalyzes the rate-limiting step in dNTP synthesis NP_829640.1 catalyzes the rate-limiting step in dNTP synthesis NP_829641.1 similar to GB:D14982, GB:Z33123, SP:P43044, PID:416242, and SP:P35879; identified by sequence similarity NP_829642.1 similar to GB:D14982, GB:Z33123, SP:P43044, PID:416242, GB:D14982, GB:Z33123, SP:P43044, and PID:416242; identified by sequence similarity NP_829643.1 similar to GB:D14982, GB:Z33123, SP:P43044, and PID:416242; identified by sequence similarity NP_829644.1 similar to GB:D14982, GB:Z33123, SP:P43044, and PID:416242; identified by sequence similarity NP_829645.1 similar to GB:D14982, GB:Z33123, SP:P43044, and PID:416242; identified by sequence similarity NP_829646.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle NP_829647.1 catalyzes the interconversion of succinyl-CoA and succinate NP_829648.1 identified by match to PFAM protein family HMM PF02881 NP_829649.1 similar to GP:7190243, and GP:7190243; identified by sequence similarity NP_829650.1 similar to GB:M86713, SP:P31522, PID:155488, and PID:1322009; identified by sequence similarity NP_829651.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source NP_829652.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate NP_829654.1 similar to GB:X69464, PID:398210, and PID:398211; identified by sequence similarity NP_829655.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate; lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM NP_829656.1 similar to GP:6382503; identified by sequence similarity NP_829657.1 identified by match to PFAM protein family HMM PF02646 NP_829658.1 identified by match to PFAM protein family HMM PF03597 NP_829660.1 identified by match to PFAM protein family HMM PF02470 NP_829662.1 similar to GP:6899664; identified by sequence similarity NP_829663.1 similar to GP:2246532; identified by sequence similarity NP_829664.1 identified by match to PFAM protein family HMM PF02912 NP_829666.1 similar to GB:X69464, PID:398210, PID:398211, GB:X69464, PID:398210, and PID:398211; identified by sequence similarity NP_829667.1 identified by match to TIGR protein family HMM TIGR01609 NP_829668.1 similar to GB:X69464, PID:398210, PID:398211, GB:X69464, PID:398210, and PID:398211; identified by sequence similarity NP_829669.1 similar to GP:6172401; identified by sequence similarity NP_829670.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY NP_829671.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not NP_829673.1 similar to GB:X69464, PID:398210, and PID:398211; identified by sequence similarity NP_829674.1 similar to GB:U00006, SP:P16528, GB:M31761, PID:146438, PID:146441, PID:396353, GB:U00096, and PID:1790449; identified by sequence similarity NP_829675.1 similar to GB:U00006, SP:P16528, GB:M31761, PID:146438, PID:146441, PID:396353, GB:U00096, and PID:1790449; identified by sequence similarity NP_829676.1 similar to GB:U00006, SP:P16528, GB:M31761, PID:146438, PID:146441, PID:396353, GB:U00096, and PID:1790449; identified by sequence similarity NP_829678.1 catalyzes the phosphorylation of 4-diphosphocytidyl-2-C-methyl-D-erythritol in the nonmevalonate pathway of isoprenoid biosynthesis NP_829679.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk NP_829680.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit NP_829681.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 NP_829682.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation NP_829683.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response NP_829684.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose NP_829685.1 identified by match to PFAM protein family HMM PF02466 NP_829686.1 similar to GP:8979320; identified by sequence similarity NP_829688.1 similar to GP:7190214; identified by sequence similarity NP_829689.1 similar to GB:M59466, SP:P24153, PID:155308, GB:M59466, SP:P24153, and PID:155308; identified by sequence similarity NP_829690.1 similar to GB:M59466, SP:P24153, and PID:155308; identified by sequence similarity NP_829691.1 synthesizes RNA primers at the replication forks NP_829692.1 This protein performs the mismatch recognition step during the DNA repair process NP_829693.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision NP_829694.1 identified by match to PFAM protein family HMM PF03780 NP_829695.1 similar to GB:X72700, and PID:288292; identified by sequence similarity NP_829696.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif NP_829697.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif NP_829698.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates NP_829699.1 identified by match to PFAM protein family HMM PF02834 NP_829701.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA NP_829702.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 NP_829705.1 similar to GB:L12145, SP:Q08633, PID:470687, PID:558154, GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829707.1 similar to GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829708.1 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity NP_829709.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine NP_829710.1 Synthesizes thioester adducts of fatty acids enzymatically to the phosphopantetheine group of acyl carrier protein NP_829711.1 similar to SP:P00808, GB:X05798, GB:V00093, SP:P00808, GB:X05798, and GB:V00093; identified by sequence similarity NP_829712.1 similar to GP:8698799, SP:P00808, GB:X05798, and GB:V00093; identified by sequence similarity NP_829713.1 identified by match to PFAM protein family HMM PF02812 NP_829714.1 catalyzes the hydrolysis of pyrophosphate to phosphate NP_829715.1 identified by match to PFAM protein family HMM PF00293 NP_829716.1 FabF, beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP. NP_829717.1 similar to SP:P06565, GB:Z33876, and PID:493469; identified by sequence similarity NP_829718.1 similar to GB:M22916, GB:L10505, SP:P39790, PID:143210, PID:143702, GB:AL009126, GB:M22916, GB:L10505, SP:P39790, PID:143210, PID:143702, and GB:AL009126; identified by sequence similarity NP_829719.1 similar to GP:8547445; identified by sequence similarity NP_829720.1 similar to GP:7190185; identified by sequence similarity NP_829721.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity NP_829722.1 identified by match to TIGR protein family HMM TIGR00377 NP_829723.1 similar to GB:X72832; identified by sequence similarity NP_829724.1 similar to GB:X72832, GB:J05175, SP:P16442, PID:1783208, PID:1783212, PID:1783214, PID:1783218, PID:1783226, PID:2352626, PID:340078, and PID:992596; identified by sequence similarity NP_829725.1 identified by match to PFAM protein family HMM PF00013 NP_829726.1 catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine and catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis NP_829727.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis NP_829728.1 similar to GB:L16784, SP:P33395, and PID:290384; identified by sequence similarity NP_829729.1 similar to GB:L10328, SP:P04846, GB:M12163, PID:146649, PID:290510, GB:U00096, and PID:1790093; identified by sequence similarity NP_829730.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation NP_829731.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan NP_829732.1 similar to GB:L21902, SP:P38945, and PID:347073; identified by sequence similarity NP_829733.1 similar to GB:L21902, SP:P38945, and PID:347073; identified by sequence similarity NP_829734.1 similar to GB:L21902, SP:P38945, PID:347073, GB:L21902, SP:P38945, and PID:347073; identified by sequence similarity NP_829735.1 similar to GB:L21902, SP:P38945, and PID:347073; identified by sequence similarity NP_829736.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA NP_829737.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile NP_829738.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase NP_829739.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_829740.1 identified by match to PFAM protein family HMM PF03158 NP_829741.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III NP_829742.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III NP_829743.1 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX NP_829744.1 similar to GP:7189892; identified by sequence similarity NP_829746.1 similar to GP:8979259; identified by sequence similarity NP_829747.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex NP_829748.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm NP_829749.1 similar to GB:L25079, SP:P42823, and PID:529424; identified by sequence similarity NP_829750.1 similar to GB:X75338, and PID:406607; identified by sequence similarity NP_829751.1 similar to GP:8979252; identified by sequence similarity NP_829752.1 similar to GB:X75338, PID:406607, GB:X75338, and PID:406607; identified by sequence similarity NP_829753.1 similar to GB:X75338, and PID:406607; identified by sequence similarity NP_829754.1 similar to GB:X75338, and PID:406607; identified by sequence similarity NP_829755.1 similar to GB:X75338, and PID:406607; identified by sequence similarity NP_829756.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not NP_829757.1 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate NP_829758.1 identified by match to PFAM protein family HMM PF02579 NP_829759.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_829760.1 similar to GB:L20805, and PID:305386; identified by sequence similarity NP_829761.1 identified by match to PFAM protein family HMM PF02442 NP_829762.1 similar to GB:L20805, and PID:305386; identified by sequence similarity NP_829763.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon NP_829764.1 similar to GB:L20805, and PID:305386; identified by sequence similarity NP_829765.1 catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate NP_829766.1 similar to GB:L20805, and PID:305386; identified by sequence similarity NP_829767.1 similar to GB:L20805, and PID:305386; identified by sequence similarity NP_829768.1 similar to GB:S85353, and PID:246437; identified by sequence similarity NP_829769.1 similar to GB:S85353, and PID:246437; identified by sequence similarity NP_829770.1 involved in type III protein export NP_829771.1 similar to GB:S85353, and PID:246437; identified by sequence similarity NP_829772.1 similar to GB:D28770, PID:523232, PID:523234, and PID:2335043; identified by sequence similarity NP_829773.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate NP_829774.1 similar to GB:D28770, PID:523232, PID:523234, and PID:2335043; identified by sequence similarity NP_829775.1 similar to GB:M35514, SP:P13380, GB:M97156, GB:M97157, GB:U02559, GB:U02560, and PID:153821; identified by sequence similarity NP_829776.1 identified by match to PFAM protein family HMM PF03081 NP_829777.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP NP_829778.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_829779.1 similar to GB:X77864, PID:951038, and PID:1333728; identified by sequence similarity NP_829780.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer NP_829781.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates NP_829782.1 binds and unfolds substrates as part of the ClpXP protease NP_829783.1 similar to GB:M21161, SP:P13421, and PID:152864; identified by sequence similarity NP_829784.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains NP_829786.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins NP_829787.1 similar to GB:M88334, SP:P25526, PID:147901, GB:U00096, and PID:1789015; identified by sequence similarity NP_829788.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine NP_829789.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE NP_829790.1 similar to SP:P39788; identified by sequence similarity NP_829791.1 identified by match to PFAM protein family HMM PF02665 NP_829792.1 similar to GB:M57961, and PID:149570; identified by sequence similarity NP_829793.1 similar to GB:M57961, and PID:149570; identified by sequence similarity NP_829794.1 E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide NP_829795.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group NP_829796.1 similar to GB:L13940, PID:295432, and SP:P54297; identified by sequence similarity NP_829797.1 similar to GB:L13940, PID:295432, SP:P54297, GB:L13940, PID:295432, and SP:P54297; identified by sequence similarity NP_829798.1 similar to GB:X05302; identified by sequence similarity NP_829799.1 similar to GB:X05302; identified by sequence similarity NP_829800.1 similar to GB:X05302; identified by sequence similarity NP_829801.1 identified by match to PFAM protein family HMM PF02537 NP_829802.1 identified by match to PFAM protein family HMM PF03208 NP_829803.1 identified by match to TIGR protein family HMM TIGR01529 NP_829805.1 similar to GB:M34239, SP:P33119, GB:M80338, PID:144973, and PID:144977; identified by sequence similarity NP_829806.1 identified by match to TIGR protein family HMM TIGR01710 NP_829807.1 similar to GB:L05176, SP:Q02540, and PID:151181; identified by sequence similarity NP_829808.1 similar to GB:L05176, SP:Q02540, and PID:151181; identified by sequence similarity NP_829809.1 similar to GB:X73124, SP:P39587, PID:413943, and GB:AL009126; identified by sequence similarity NP_829811.1 similar to GB:X73124, SP:P39587, PID:413943, and GB:AL009126; identified by sequence similarity NP_829812.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex NP_829813.1 similar to GP:7190892; identified by sequence similarity NP_829814.1 similar to GB:L25079, SP:P42823, and PID:529424; identified by sequence similarity NP_829815.1 similar to GP:7190894; identified by sequence similarity NP_829816.1 similar to GP:7190895; identified by sequence similarity NP_829817.1 identified by match to PFAM protein family HMM PF02592 NP_829818.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) NP_829819.1 similar to GB:M99391, and PID:152478; identified by sequence similarity NP_829820.1 similar to GB:M55546, SP:P23988, PID:154233, GB:L04791, SP:Q03468, and PID:182181; identified by sequence similarity NP_829821.1 similar to GB:M55546, SP:P23988, and PID:154233; identified by sequence similarity NP_829822.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA NP_829823.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion NP_829824.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis NP_829825.1 similar to GB:U00006, SP:P16528, GB:M31761, PID:146438, PID:146441, PID:396353, GB:U00096, and PID:1790449; identified by sequence similarity NP_829826.1 similar to GB:U00006, SP:P16528, GB:M31761, PID:146438, PID:146441, PID:396353, GB:U00096, and PID:1790449; identified by sequence similarity NP_829827.1 identified by match to PFAM protein family HMM PF02889 NP_829828.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase NP_829829.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol NP_829830.1 similar to GB:X56071, PID:507063, and SP:P51603; identified by sequence similarity NP_829831.1 identified by match to PFAM protein family HMM PF01026 NP_829832.1 identified by match to PFAM protein family HMM PF02411 NP_829833.1 similar to GB:M59466, SP:P24153, and PID:155308; identified by sequence similarity NP_829834.1 similar to GP:7190914; identified by sequence similarity NP_829835.1 similar to GP:8979156; identified by sequence similarity NP_829836.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA NP_829837.1 identified by match to PFAM protein family HMM PF00691 NP_829838.1 similar to GB:X76500, and PID:520921; identified by sequence similarity NP_829839.1 similar to GB:X76500, and PID:520921; identified by sequence similarity NP_829840.1 similar to GP:5457310; identified by sequence similarity NP_829841.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is not essential for growth NP_829842.1 similar to GP:7190922, and GP:7190922; identified by sequence similarity NP_829843.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine NP_829844.1 similar to GB:D10387, SP:P27735, PID:216968, and PID:47275; identified by sequence similarity NP_829845.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine NP_829846.1 similar to GB:D10387, SP:P27735, PID:216968, and PID:47275; identified by sequence similarity NP_829847.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen NP_829848.1 similar to GB:M94110, SP:Q04441, and PID:142786; identified by sequence similarity NP_829849.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity NP_829850.1 similar to GB:M20181, GB:M13239, SP:P08407, GB:M20146, and PID:147094; identified by sequence similarity NP_829851.1 similar to GB:M20181, GB:M13239, SP:P08407, GB:M20146, and PID:147094; identified by sequence similarity NP_829852.1 similar to GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829853.1 similar to GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829854.1 similar to GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829855.1 similar to GB:L12145, SP:Q08633, PID:470687, and PID:558154; identified by sequence similarity NP_829856.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs NP_829857.1 similar to GP:7190927; identified by sequence similarity NP_829858.1 similar to GP:8979133; identified by sequence similarity NP_829859.1 identified by match to PFAM protein family HMM PF00186 NP_829860.1 identified by match to TIGR protein family HMM TIGR01498 NP_829861.1 similar to EGAD|163839; identified by sequence similarity NP_829862.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released NP_829863.1 identified by match to TIGR protein family HMM TIGR01000 NP_829864.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase NP_829865.1 similar to GB:M22916, GB:L10505, SP:P39790, PID:143210, PID:143702, and GB:AL009126; identified by sequence similarity NP_829866.1 similar to GP:8979125; identified by sequence similarity NP_829867.1 identified by match to PFAM protein family HMM PF02616 NP_829868.1 identified by match to TIGR protein family HMM TIGR01387 NP_829869.1 identified by match to PFAM protein family HMM PF00132 NP_829870.1 similar to SP:O66126, and GB:X72832; identified by sequence similarity NP_829871.1 similar to GP:7190947, and GP:7190947; identified by sequence similarity NP_829872.1 similar to GB:M35514, SP:P13380, GB:M97156, GB:M97157, GB:U02559, GB:U02560, and PID:153821; identified by sequence similarity NP_829874.1 similar to PIR:H39999, GB:L04791, SP:Q03468, and PID:182181; identified by sequence similarity; putative NP_829875.1 similar to SP:P10561, GB:X64318, GB:U26173, GB:S79880, PID:1237118, and PID:30956; identified by sequence similarity; putative NP_829876.1 identified by match to PFAM protein family HMM PF00589 NP_829877.1 similar to SP:P10555; identified by sequence similarity; putative NP_829878.1 similar to GB:M60502, GB:M24355, GB:M96943, GB:M60500, GB:L01089, GB:M60494, GB:M60499, GB:M60501, GB:M60503, GB:M60495, GB:L01090, SP:P20930, and PID:190394; identified by sequence similarity; putative NP_829879.1 similar to SP:P10557, GB:X52947, GB:M65188, SP:P17302, PID:181209, and PID:29917; identified by sequence similarity; putative NP_829880.1 similar to GP:1124830, GB:X06869, SP:P08736, PID:157401, and PID:7915; identified by sequence similarity; putative