-- dump date 20140619_041042 -- class Genbank::CDS -- table cds_note -- id note YP_001942088.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001942089.1 KEGG: plt:Plut_0001 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta chain YP_001942090.1 TIGRFAM: DNA replication and repair protein RecF; PFAM: SMC domain protein; KEGG: plt:Plut_0002 RecF protein YP_001942091.1 KEGG: cch:Cag_2009 hypothetical protein YP_001942092.1 PFAM: beta-lactamase domain protein; flavodoxin/nitric oxide synthase; KEGG: cph:Cpha266_0026 beta-lactamase domain protein YP_001942093.1 PFAM: DNA polymerase B exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: cph:Cpha266_0027 DNA polymerase B region YP_001942094.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001942095.1 KEGG: cph:Cpha266_0029 thiosulfate-binding protein SoxY YP_001942096.1 PFAM: Sulphur oxidation protein SoxZ; KEGG: cph:Cpha266_0030 sulfur oxidation protein SoxZ YP_001942097.1 PFAM: cytochrome c class I; KEGG: pvi:Cvib_0008 sulfide dehydrogenase (flavocytochrome), cytochrome c subunit YP_001942098.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Flavocytochrome c sulphide dehydrogenase flavin-binding; KEGG: cph:Cpha266_0032 sulfide dehydrogenase (flavocytochrome), flavoprotein subunit YP_001942099.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001942100.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001942101.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; KEGG: cph:Cpha266_0035 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001942102.1 KEGG: cph:Cpha266_0036 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase subunit B domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA topoisomerase type IIA subunit B region 2 domain protein; SMART: DNA topoisomerase II YP_001942103.1 PFAM: protein of unknown function UPF0102; KEGG: cph:Cpha266_0037 hypothetical protein YP_001942104.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001942105.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: cph:Cpha266_0040 ribonuclease, Rne/Rng family YP_001942106.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001942107.1 KEGG: cph:Cpha266_0042 C-terminal processing peptidase-3. Serine peptidase. MEROPS family S41A; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001942108.1 KEGG: cph:Cpha266_0043 hypothetical protein YP_001942109.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: cch:Cag_0035 geranylgeranyl reductase YP_001942110.1 Catalyzes a two-step reaction, first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001942111.1 KEGG: pvi:Cvib_0150 hypothetical protein YP_001942112.1 KEGG: pvi:Cvib_0150 hypothetical protein YP_001942113.1 PFAM: ATP-dependent Clp protease adaptor protein ClpS; KEGG: plt:Plut_0018 hypothetical protein YP_001942114.1 PFAM: peptidase U61 LD-carboxypeptidase A; KEGG: cph:Cpha266_0047 muramoyltetrapeptide carboxypeptidase YP_001942115.1 PFAM: H+transporting two-sector ATPase delta/epsilon subunit; KEGG: plt:Plut_0020 ATP synthase F1, epsilon subunit YP_001942116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001942117.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cch:Cag_2013 thiol:disulfide interchange protein, thioredoxin family protein YP_001942118.1 catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using GTP YP_001942119.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: cph:Cpha266_0843 membrane protein involved in aromatic hydrocarbon degradation YP_001942120.1 PFAM: protein of unknown function DUF1458; KEGG: cte:CT2229 hypothetical protein YP_001942121.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; Polysulphide reductase NrfD; KEGG: cph:Cpha266_0119 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942122.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: cph:Cpha266_0120 formate dehydrogenase YP_001942123.1 PFAM: protein of unknown function DUF81; KEGG: pvi:Cvib_0032 protein of unknown function DUF81 YP_001942124.1 KEGG: cph:Cpha266_0122 hypothetical protein YP_001942125.1 PFAM: SirA family protein; KEGG: plt:Plut_0033 hypothetical protein YP_001942126.1 KEGG: cch:Cag_1961 hypothetical protein YP_001942128.1 KEGG: cph:Cpha266_0053 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; Helicase superfamily 1 and 2 ATP-binding; SMART: DEAD-like helicases YP_001942129.1 KEGG: rci:RCIX2578 hypothetical protein YP_001942130.1 PFAM: regulatory protein TetR; KEGG: cph:Cpha266_0060 TetR family transcriptional regulator YP_001942131.1 KEGG: cph:Cpha266_0061 transmembrane protein YP_001942132.1 KEGG: cph:Cpha266_0062 NADPH-dependent FMN reductase YP_001942133.1 KEGG: cph:Cpha266_0064 hypothetical protein YP_001942134.1 KEGG: fgr:FG06081.1 hypothetical protein YP_001942135.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: tbd:Tbd_2169 hypothetical protein YP_001942137.1 KEGG: cph:Cpha266_0751 hypothetical protein YP_001942138.1 PFAM: PASTA domain containing protein; KEGG: cph:Cpha266_0750 PASTA domain containing protein YP_001942139.1 KEGG: cph:Cpha266_0063 hypothetical protein YP_001942140.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cph:Cpha266_0073 DNA methylase N-4/N-6 domain protein YP_001942141.1 KEGG: sat:SYN_02435 hypothetical cytosolic protein YP_001942142.1 KEGG: pol:Bpro_0004 hypothetical protein YP_001942144.1 KEGG: cph:Cpha266_0084 hypothetical protein YP_001942145.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: cph:Cpha266_0085 4'-phosphopantetheinyl transferase YP_001942146.1 KEGG: cph:Cpha266_0086 hypothetical protein YP_001942147.1 PFAM: protein of unknown function DUF894 DitE; major facilitator superfamily MFS_1; KEGG: cph:Cpha266_0087 major facilitator superfamily MFS_1 YP_001942148.1 KEGG: cph:Cpha266_0088 hypothetical protein YP_001942149.1 KEGG: cph:Cpha266_0089 Gifsy-1 prophage protein YP_001942150.1 TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: cph:Cpha266_0090 methionine-R-sulfoxide reductase YP_001942151.1 KEGG: cph:Cpha266_0091 twitching mobility protein PilT YP_001942152.1 PFAM: SpoVT/AbrB domain protein; KEGG: cph:Cpha266_0092 virulence associated protein B YP_001942153.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: cph:Cpha266_0093 drug resistance transporter, EmrB/QacA subfamily YP_001942154.1 PFAM: secretion protein HlyD family protein; KEGG: cph:Cpha266_0094 secretion protein HlyD family protein YP_001942155.1 PFAM: UspA domain protein; KEGG: cph:Cpha266_0095 UspA domain protein YP_001942156.1 PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0096 outer membrane efflux protein YP_001942157.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_0097 DNA-binding protein fis / Fis family transcriptional regulator YP_001942158.1 PFAM: aminotransferase class I and II; KEGG: cte:CT0110 aminotransferase, class I YP_001942159.1 PFAM: amino acid-binding ACT domain protein; KEGG: cph:Cpha266_1971 amino acid-binding ACT domain protein YP_001942160.1 KEGG: cph:Cpha266_1968 phenylacetate-CoA ligase YP_001942161.1 Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates. YP_001942162.1 PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cte:CT0114 ferredoxin oxidoreductase, alpha subunit YP_001942163.1 KEGG: cte:CT0116 ArsA ATPase family protein; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001942164.1 KEGG: cph:Cpha266_0761 hypothetical protein YP_001942165.1 KEGG: amr:AM1_H0103 hypothetical protein YP_001942166.1 PFAM: nitroreductase; KEGG: cph:Cpha266_2684 nitroreductase YP_001942167.1 KEGG: plt:Plut_0074 hypothetical protein YP_001942168.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001942169.1 TIGRFAM: membrane-associated zinc metalloprotease; PFAM: PDZ/DHR/GLGF domain protein; peptidase M50; KEGG: cph:Cpha266_2681 RseP peptidase. Metallo peptidase. MEROPS family M50B YP_001942170.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001942171.1 catalyzes the hydrolysis of acylphosphate YP_001942172.1 KEGG: cph:Cpha266_2678 FtsH-2 peptidase. Metallo peptidase. MEROPS family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase AAA; peptidase M41 FtsH extracellular; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001942173.1 TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: plt:Plut_0079 orotidine 5'-phosphate decarboxylase subfamily 2 YP_001942174.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001942175.1 KEGG: cph:Cpha266_1070 hypothetical protein YP_001942176.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; domain of unknown function DUF1731; KEGG: cph:Cpha266_2675 domain of unknown function DUF1731 YP_001942177.1 PFAM: Ferritin Dps family protein; KEGG: cph:Cpha266_2674 ferritin, Dps family protein YP_001942178.1 PFAM: RNP-1 like RNA-binding protein; KEGG: cph:Cpha266_2673 RNP-1 like RNA-binding protein YP_001942179.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: cph:Cpha266_2672 ammonium transporter YP_001942180.1 PFAM: nitrogen regulatory protein P-II; KEGG: cch:Cag_1998 nitrogen regulatory protein P-II (GlnB, GlnK) YP_001942181.1 PFAM: hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_2669 hypothetical protein YP_001942182.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: plt:Plut_0093 segregation and condensation protein A YP_001942183.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: wsu:WS0422 hypothetical protein YP_001942184.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_2667 uncharacterised conserved protein UCP033563 YP_001942185.1 PFAM: protein of unknown function UPF0079; KEGG: cph:Cpha266_2666 protein of unknown function UPF0079 YP_001942186.1 PFAM: peptidase M22 glycoprotease; KEGG: cph:Cpha266_2665 peptidase M22, glycoprotease YP_001942187.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: cph:Cpha266_2664 iojap-like protein YP_001942188.1 KEGG: cph:Cpha266_2663 DNA gyrase subunit A; TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller YP_001942189.1 SMART: zinc finger CDGSH-type domain protein; KEGG: cph:Cpha266_2662 zinc finger, CDGSH-type domain protein YP_001942190.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001942191.1 PFAM: RES domain protein; KEGG: gur:Gura_0589 hypothetical protein YP_001942192.1 KEGG: pvi:Cvib_0659 hypothetical protein YP_001942193.1 PFAM: HipA domain protein; KEGG: cph:Cpha266_2264 HipA domain protein YP_001942194.1 SMART: helix-turn-helix domain protein; KEGG: cph:Cpha266_2265 helix-turn-helix domain protein YP_001942195.1 KEGG: cph:Cpha266_1216 hypothetical protein YP_001942196.1 PFAM: plasmid stabilization system; KEGG: cph:Cpha266_1217 plasmid stabilization system YP_001942197.1 PFAM: Domain of unknown function DUF1814; KEGG: cph:Cpha266_0782 hypothetical protein YP_001942198.1 KEGG: cph:Cpha266_0781 hypothetical protein YP_001942200.1 PFAM: IstB domain protein ATP-binding protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_2659 IstB domain protein ATP-binding protein YP_001942201.1 KEGG: ava:Ava_1156 type I site-specific deoxyribonuclease HsdR YP_001942202.1 KEGG: noc:Noc_0639 hypothetical protein YP_001942204.1 KEGG: wsu:WS1135 hypothetical protein YP_001942206.1 KEGG: pau:PA14_15610 hypothetical protein YP_001942207.1 PFAM: restriction modification system DNA specificity domain; N-6 DNA methylase; KEGG: cph:Cpha266_0895 N-6 DNA methylase YP_001942208.1 PFAM: type III restriction protein res subunit; protein of unknown function DUF450; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_0896 type III restriction enzyme, res subunit YP_001942209.1 KEGG: cph:Cpha266_0759 hypothetical protein YP_001942210.1 PFAM: regulatory protein ArsR; KEGG: cph:Cpha266_0758 ArsR family transcriptional regulator YP_001942211.1 PFAM: permease; KEGG: cph:Cpha266_0757 permease YP_001942212.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cph:Cpha266_0756 PHP C-terminal domain protein YP_001942213.1 TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase; KEGG: cph:Cpha266_0755 catalase/peroxidase HPI YP_001942214.1 PFAM: ferric-uptake regulator; KEGG: cph:Cpha266_0754 ferric uptake regulator, Fur family YP_001942215.1 KEGG: cph:Cpha266_0752 hypothetical protein YP_001942216.1 KEGG: cph:Cpha266_0752 hypothetical protein YP_001942217.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cph:Cpha266_2592 magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase YP_001942218.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cph:Cpha266_2591 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001942219.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase FGGY; KEGG: cph:Cpha266_2590 glycerol kinase YP_001942220.1 KEGG: plt:Plut_0585 hypothetical protein YP_001942221.1 PFAM: thioesterase superfamily protein; KEGG: cph:Cpha266_2516 thioesterase superfamily protein YP_001942222.1 KEGG: cph:Cpha266_2515 hypothetical protein YP_001942223.1 PFAM: glycosyl transferase family 9; KEGG: cph:Cpha266_2514 glycosyl transferase, family 9 YP_001942224.1 KEGG: cph:Cpha266_2513 exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase YP_001942225.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001942226.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cph:Cpha266_2511 single-strand binding protein YP_001942227.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001942228.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001942229.1 KEGG: cph:Cpha266_2508 hypothetical protein YP_001942230.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001942231.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001942232.1 PFAM: ribosomal protein L35; KEGG: cte:CT2128 50S ribosomal protein L35 YP_001942233.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001942234.1 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) YP_001942235.1 TIGRFAM: chlorophyllide reductase subunit Z; PFAM: oxidoreductase/nitrogenase component 1; protein of unknown function DUF1197; KEGG: cph:Cpha266_2500 chlorophyllide reductase subunit Z YP_001942236.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: cph:Cpha266_2499 glycoside hydrolase, family 3 domain protein YP_001942237.1 PFAM: Asparaginase/glutaminase; KEGG: pgi:PG2121 L-asparaginase YP_001942238.1 KEGG: cph:Cpha266_2498 CMP/dCMP deaminase, zinc-binding YP_001942239.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001942240.1 PFAM: HNH endonuclease; SMART: HNH nuclease; KEGG: pvi:Cvib_0193 HNH endonuclease YP_001942241.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein YP_001942242.1 PFAM: ribonuclease III; double-stranded RNA binding domain protein; KEGG: cph:Cpha266_2495 ribonuclease III YP_001942243.1 TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: Beta-ketoacyl synthase; KEGG: cph:Cpha266_2494 3-oxoacyl-[acyl-carrier-protein] synthase II YP_001942244.1 carries the fatty acid chain in fatty acid biosynthesis YP_001942245.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: plt:Plut_0131 3-oxoacyl-(acyl-carrier-protein) reductase YP_001942246.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: cph:Cpha266_2491 [acyl-carrier-protein] S-malonyltransferase YP_001942247.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001942248.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001942249.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001942250.1 PFAM: protein of unknown function DUF177; KEGG: cte:CT2111 hypothetical protein YP_001942251.1 KEGG: plt:Plut_0330 uridine kinase-like YP_001942252.1 KEGG: cph:Cpha266_1834 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001942253.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: plt:Plut_1358 PAS/PAC sensor signal transduction histidine kinase YP_001942254.1 PFAM: response regulator receiver; KEGG: tle:Tlet_0986 two component transcriptional regulator, winged helix family YP_001942255.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: plt:Plut_1978 rubredoxin-like YP_001942256.1 TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; KEGG: drm:Dred_0778 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001942257.1 PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; KEGG: cph:Cpha266_0167 glutamate dehydrogenase (NAD/NADP) YP_001942258.1 PFAM: protein of unknown function DUF52; KEGG: mgm:Mmc1_2152 protein of unknown function DUF52 YP_001942259.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001942260.1 KEGG: cph:Cpha266_0219 photosystem P840 reaction center, large subunit YP_001942261.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_0220 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942262.1 PFAM: glycosyl transferase family 2; KEGG: plt:Plut_1974 dolichyl-phosphate beta-D-mannosyltransferase YP_001942263.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001942264.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001942265.1 PFAM: Septum formation initiator; KEGG: cph:Cpha266_0224 septum formation initiator YP_001942266.1 KEGG: cph:Cpha266_0225 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: IspG family protein YP_001942267.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_0226 short-chain dehydrogenase/reductase SDR YP_001942268.1 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001942269.1 TIGRFAM: transcription termination/antitermination factor NusG; PFAM: NGN domain protein; KEGG: cph:Cpha266_0228 transcription antitermination protein NusG YP_001942270.1 binds directly to 23S ribosomal RNA YP_001942271.1 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA YP_001942272.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001942273.1 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors YP_001942274.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001942275.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001942276.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: plt:Plut_1960 acetyl-CoA carboxylase, biotin carboxylase YP_001942277.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: cph:Cpha266_0236 biotin carboxyl carrier protein YP_001942278.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001942279.1 PFAM: histone family protein DNA-binding protein; KEGG: cte:CT0160 DNA-binding protein HU-beta YP_001942280.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_001942281.1 catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin YP_001942282.1 PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0241 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein YP_001942283.1 KEGG: cph:Cpha266_0242 hypothetical protein YP_001942284.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001942285.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: cph:Cpha266_0244 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001942286.1 KEGG: cph:Cpha266_0245 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942287.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_0246 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942288.1 PFAM: HipA domain protein; KEGG: cph:Cpha266_0247 HipA domain protein YP_001942289.1 TIGRFAM: HipA N-terminal domain protein; KEGG: cph:Cpha266_0248 hypothetical protein YP_001942290.1 TIGRFAM: transcriptional regulator, y4mF family; PFAM: helix-turn-helix domain protein; KEGG: cph:Cpha266_0249 XRE family transcriptional regulator YP_001942291.1 PFAM: Domain of unknown function DUF1814; KEGG: ajs:Ajs_1569 hypothetical protein YP_001942292.1 KEGG: cph:Cpha266_0646 hypothetical protein YP_001942294.1 KEGG: cph:Cpha266_0250 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3 YP_001942295.1 KEGG: cph:Cpha266_0270 hypothetical protein YP_001942296.1 KEGG: pvi:Cvib_1663 hypothetical protein YP_001942297.1 KEGG: pvi:Cvib_1663 hypothetical protein YP_001942298.1 PFAM: integrase; KEGG: pna:Pnap_4798 phage integrase family protein YP_001942299.1 PFAM: transposase IS4 family protein; KEGG: dol:Dole_3091 transposase IS4 family protein YP_001942300.1 KEGG: fjo:Fjoh_3535 hypothetical protein YP_001942301.1 KEGG: fjo:Fjoh_3534 hypothetical protein YP_001942303.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001942304.1 KEGG: smr:Smar_0369 hypothetical protein YP_001942305.1 PFAM: IstB domain protein ATP-binding protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_2659 IstB domain protein ATP-binding protein YP_001942306.1 TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family; PFAM: Nucleotidyltransferase substrate binding protein HI0074; KEGG: cph:Cpha266_0291 nucleotidyltransferase substrate binding protein, HI0074 family YP_001942307.1 PFAM: DNA polymerase beta domain protein region; KEGG: cph:Cpha266_0292 DNA polymerase, beta domain protein region YP_001942308.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: gme:Gmet_0160 pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001942309.1 KEGG: pna:Pnap_4866 hypothetical protein YP_001942310.1 SMART: helix-turn-helix domain protein; KEGG: pvi:Cvib_0653 XRE family transcriptional regulator YP_001942311.1 PFAM: HipA domain protein; KEGG: cak:Caul_5344 HipA domain protein YP_001942312.1 KEGG: cph:Cpha266_0299 DNA helicase YP_001942313.1 KEGG: cch:Cag_1322 hypothetical protein YP_001942314.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001942315.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001942316.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cph:Cpha266_0301 penicillin-binding protein, 1A family YP_001942317.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_0302 alpha/beta hydrolase fold YP_001942318.1 PFAM: SNARE associated Golgi protein; KEGG: cph:Cpha266_0303 DedA protein YP_001942319.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cph:Cpha266_0305 amine oxidase YP_001942320.1 KEGG: cph:Cpha266_0306 hypothetical protein YP_001942321.1 KEGG: cph:Cpha266_0307 hypothetical protein YP_001942322.1 KEGG: mmi:MMAR_2580 hypothetical protein YP_001942323.1 PFAM: beta-lactamase domain protein; KEGG: cph:Cpha266_0308 beta-lactamase domain protein YP_001942324.1 PFAM: surface antigen msp4 family protein; KEGG: cph:Cpha266_0309 outer surface protein YP_001942325.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: cph:Cpha266_0311 NAD-dependent epimerase/dehydratase YP_001942326.1 TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: cph:Cpha266_0312 cobyrinate a,c-diamide synthase / hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) YP_001942327.1 KEGG: cph:Cpha266_0313 hypothetical protein YP_001942328.1 KEGG: cph:Cpha266_0333 hypothetical protein YP_001942329.1 PFAM: UvrB/UvrC protein; ATPase AAA; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_0334 ATPase AAA-2 domain protein YP_001942330.1 catalyzes the formation of L-tryptophan from indole and L-serine YP_001942332.1 KEGG: cph:Cpha266_0336 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001942333.1 KEGG: cph:Cpha266_0337 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001942334.1 KEGG: cph:Cpha266_0338 hypothetical protein YP_001942335.1 KEGG: cph:Cpha266_0339 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001942336.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: cph:Cpha266_0340 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001942337.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: cph:Cpha266_0341 phosphoenolpyruvate--protein phosphotransferase YP_001942338.1 TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase domain protein; KEGG: cch:Cag_1608 DnaB helicase YP_001942339.1 TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; KEGG: cph:Cpha266_0343 phage SPO1 DNA polymerase-related protein YP_001942340.1 KEGG: pvi:Cvib_1568 phosphopantothenate-cysteine ligase / phosphopantothenoylcysteine decarboxylase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001942341.1 KEGG: cph:Cpha266_0345 hypothetical protein YP_001942342.1 TIGRFAM: cytidyltransferase-related domain protein; rfaE bifunctional protein; PFAM: cytidylyltransferase; KEGG: cph:Cpha266_0346 RfaE bifunctional protein YP_001942343.1 KEGG: mmw:Mmwyl1_0817 DNA polymerase, beta domain protein region YP_001942345.1 PFAM: lipid A biosynthesis acyltransferase; KEGG: pvi:Cvib_0671 lipid A biosynthesis acyltransferase YP_001942346.1 PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; KEGG: pvi:Cvib_0672 ABC transporter YP_001942348.1 KEGG: bcl:ABC1230 hypothetical protein YP_001942350.1 PFAM: glycosyl transferase group 1; KEGG: cch:Cag_1477 glycosyl transferase YP_001942351.1 PFAM: glycosyl transferase family 2; KEGG: nar:Saro_0724 glycosyl transferase, family 2 YP_001942352.1 PFAM: glycosyl transferase group 1; KEGG: mca:MCA2124 colanic acid biosynthesis glycosyl transferase YP_001942353.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: amr:AM1_4475 aminotransferase, DegT/DnrJ/EryC1/StrS family YP_001942354.1 PFAM: glycosyl transferase family 9; KEGG: cte:CT0221 heptosyltransferase YP_001942355.1 PFAM: glycosyl transferase group 1; KEGG: cte:CT0224 glycosyl transferase YP_001942356.1 PFAM: glycosyl transferase group 1; KEGG: cch:Cag_1475 glycosyl transferase YP_001942357.1 KEGG: pvi:Cvib_0691 hypothetical protein YP_001942358.1 PFAM: glycosyl transferase group 1; KEGG: cch:Cag_1473 hypothetical protein YP_001942359.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_0357 glycosyl transferase, group 1 YP_001942362.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_0358 glycosyl transferase, group 1 YP_001942364.1 PFAM: glycosyl transferase group 1; KEGG: cch:Cag_1472 glycosyl transferase YP_001942365.1 PFAM: Abortive infection protein; KEGG: cph:Cpha266_0361 abortive infection protein YP_001942366.1 PFAM: phosphatidate cytidylyltransferase; KEGG: cph:Cpha266_0362 phosphatidate cytidylyltransferase YP_001942367.1 TIGRFAM: PTS system, fructose subfamily, IIA subunit; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: cph:Cpha266_0363 PTS IIA-like nitrogen-regulatory protein PtsN YP_001942368.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001942369.1 PFAM: glutaredoxin 2; KEGG: cph:Cpha266_0365 glutaredoxin 2 YP_001942370.1 KEGG: cch:Cag_1465 hypothetical protein YP_001942371.1 PFAM: protein of unknown function DUF150; KEGG: cph:Cpha266_0367 protein of unknown function DUF150 YP_001942372.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001942373.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001942374.1 PFAM: ribosome-binding factor A; KEGG: plt:Plut_1778 ribosome-binding factor A YP_001942375.1 TIGRFAM: tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; KEGG: cch:Cag_1460 tRNA pseudouridine synthase B YP_001942376.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: cph:Cpha266_0372 riboflavin kinase / FMN adenylyltransferase YP_001942377.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001942378.1 PFAM: YicC domain protein; domain of unknown function DUF1732; KEGG: cph:Cpha266_0374 hypothetical protein YP_001942379.1 Essential for recycling GMP and indirectly, cGMP YP_001942380.1 KEGG: pvi:Cvib_1554 hypothetical protein YP_001942381.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cte:CT0249 glutathione S-transferase, fosfomycin resistance protein YP_001942382.1 PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Nucleotidyl transferase; KEGG: cph:Cpha266_0378 UDP-N-acetylglucosamine pyrophosphorylase YP_001942383.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_001942384.1 PFAM: protein of unknown function DUF1239; KEGG: cph:Cpha266_0380 hypothetical protein YP_001942385.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: pvi:Cvib_1549 outer membrane chaperone Skp (OmpH) YP_001942386.1 KEGG: cte:CT0222 hypothetical protein YP_001942387.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: cph:Cpha266_0383 DNA protecting protein DprA YP_001942388.1 PFAM: Polyprenyl synthetase; KEGG: cph:Cpha266_0384 polyprenyl synthetase YP_001942389.1 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate YP_001942390.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_0386 protein of unknown function DUF214 YP_001942391.1 PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0387 ABC transporter YP_001942392.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: cph:Cpha266_0388 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_001942393.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001942394.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001942395.1 TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; KEGG: cph:Cpha266_0391 FolC bifunctional protein YP_001942396.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001942397.1 PFAM: Methyltransferase type 11; KEGG: pla:Plav_2493 methyltransferase type 11 YP_001942398.1 PFAM: Electron transfer flavoprotein alpha/beta-subunit; KEGG: pvi:Cvib_1536 electron transfer flavoprotein beta-subunit YP_001942399.1 PFAM: Electron transfer flavoprotein alpha subunit; KEGG: pvi:Cvib_1535 electron transfer flavoprotein, alpha subunit YP_001942400.1 PFAM: UvrB/UvrC protein; protein of unknown function DUF151; KEGG: cph:Cpha266_0395 protein of unknown function DUF151 YP_001942401.1 PFAM: surface antigen msp4 family protein; KEGG: cph:Cpha266_0396 hypothetical protein YP_001942402.1 TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: cph:Cpha266_0397 surface antigen (D15) YP_001942403.1 KEGG: cph:Cpha266_0398 undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001942404.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001942405.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: plt:Plut_1748 succinyl-CoA ligase, alpha subunit YP_001942406.1 KEGG: cph:Cpha266_0401 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001942407.1 KEGG: cph:Cpha266_0402 hypothetical protein YP_001942408.1 PFAM: polysaccharide biosynthesis protein; KEGG: cph:Cpha266_0403 polysaccharide biosynthesis protein YP_001942409.1 KEGG: plt:Plut_1743 hypothetical protein YP_001942410.1 KEGG: cph:Cpha266_0405 hypothetical protein YP_001942411.1 KEGG: cph:Cpha266_0407 hypothetical protein YP_001942412.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: pvi:Cvib_1522 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001942413.1 PFAM: phosphoglucomutase/phosphomannomutase ; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: cph:Cpha266_0410 phosphomannomutase YP_001942414.1 KEGG: cph:Cpha266_0411 lipid-A-disaccharide synthase; TIGRFAM: lipid-A-disaccharide synthase; PFAM: glycosyl transferase family 19 YP_001942415.1 KEGG: cph:Cpha266_0412 hypothetical protein YP_001942416.1 these proteins belong to a family of oxidoreductases related to the NADPH-dependent glutamate synthase YP_001942417.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001942418.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001942419.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001942420.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001942421.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001942422.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001942423.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: cph:Cpha266_0420 cell cycle protein YP_001942424.1 KEGG: cph:Cpha266_0422 RNA modification enzyme, MiaB family; TIGRFAM: RNA modification enzyme, MiaB family; PFAM: Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB YP_001942425.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_001942426.1 KEGG: plt:Plut_1726 hypothetical protein YP_001942427.1 KEGG: pvi:Cvib_1507 hypothetical protein YP_001942428.1 PFAM: histone family protein DNA-binding protein; KEGG: cph:Cpha266_0424 histone family protein DNA-binding protein YP_001942429.1 KEGG: cph:Cpha266_0425 hypothetical protein YP_001942430.1 KEGG: cph:Cpha266_0426 FtsH peptidase. Metallo peptidase. MEROPS family M41; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; ATPase AAA; peptidase M41 FtsH extracellular; SMART: AAA ATPase YP_001942431.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001942432.1 PFAM: hydroxyneurosporene synthase; KEGG: cph:Cpha266_0428 hydroxyneurosporene synthase YP_001942433.1 PFAM: Rieske [2Fe-2S] domain protein; Cytochrome b6-f complex Fe-S subunit; KEGG: cph:Cpha266_0429 Plastoquinol--plastocyanin reductase YP_001942434.1 PFAM: Cytochrome b/b6 domain; KEGG: plt:Plut_1718 cytochrome b-c complex, cytochrome b subunit YP_001942435.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: cph:Cpha266_0431 alpha amylase, catalytic region YP_001942437.1 KEGG: cph:Cpha266_0432 hypothetical protein YP_001942438.1 KEGG: cph:Cpha266_0433 hypothetical protein YP_001942439.1 KEGG: cph:Cpha266_0434 hypothetical protein YP_001942440.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cte:CT1766 3-oxoacyl-(acyl-carrier-protein) reductase YP_001942441.1 PFAM: protein of unknown function DUF81; KEGG: cte:CT1829 hypothetical protein YP_001942443.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0438 ABC transporter YP_001942444.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sun:SUN_2103 molybdenum ABC transporter, permease YP_001942445.1 PFAM: TOBE domain protein; KEGG: cph:Cpha266_0439 TOBE domain protein YP_001942446.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: mca:MCA1378 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001942447.1 TIGRFAM: modD protein; PFAM: Quinolinate phosphoribosyl transferase; KEGG: cph:Cpha266_0455 ModD protein YP_001942448.1 KEGG: cch:Cag_0501 periplasmic phosphate binding protein YP_001942449.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cch:Cag_0500 phosphate ABC transporter, permease protein PstC YP_001942450.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cch:Cag_0499 phosphate transport system permease protein 2 YP_001942451.1 KEGG: cch:Cag_0498 phosphate transport system permease protein 1; TIGRFAM: phosphate ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: AAA ATPase YP_001942452.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: cch:Cag_0974 PhoU YP_001942453.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: plt:Plut_0062 protein tyrosine phosphatase YP_001942454.1 TIGRFAM: arsenite oxidase, large subunit; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: ttj:TTHB127 arsenite oxidase, large subunit YP_001942455.1 TIGRFAM: arsenite oxidase, small subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: ttj:TTHB128 arsenite oxidase, small subunit YP_001942456.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001942457.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001942458.1 catalyzes branch migration in Holliday junction intermediates YP_001942459.1 TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: GTPase EngC; KEGG: pvi:Cvib_0411 ribosome small subunit-dependent GTPase A YP_001942460.1 PFAM: Aldehyde Dehydrogenase_; KEGG: cph:Cpha266_2070 aldehyde dehydrogenase YP_001942461.1 KEGG: plt:Plut_0353 hypothetical protein YP_001942462.1 KEGG: cte:CT1571 hypothetical protein YP_001942463.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cph:Cpha266_2040 protein tyrosine phosphatase YP_001942464.1 PFAM: diacylglycerol kinase catalytic region; KEGG: cph:Cpha266_2039 diacylglycerol kinase, catalytic region YP_001942465.1 KEGG: cph:Cpha266_2038 hypothetical protein YP_001942466.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001942467.1 PFAM: conserved hypothetical protein; KEGG: plt:Plut_0357 hypothetical protein YP_001942468.1 KEGG: pvi:Cvib_0417 hypothetical protein YP_001942469.1 KEGG: cph:Cpha266_2036 Fis family transcriptional regulator YP_001942470.1 KEGG: cph:Cpha266_1807 hypothetical protein YP_001942471.1 PFAM: cytochrome c assembly protein; KEGG: cte:CT1559 cytochrome c biogenesis protein YP_001942472.1 KEGG: cph:Cpha266_2035 hypothetical protein YP_001942473.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001942474.1 PFAM: surface antigen (D15); Patatin; KEGG: cph:Cpha266_2033 patatin YP_001942475.1 TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; KEGG: cph:Cpha266_2032 acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha YP_001942476.1 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor YP_001942477.1 KEGG: pvi:Cvib_0441 ATP-dependent Clp protease, proteolytic subunit ClpP; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP; PFAM: peptidase S14 ClpP YP_001942478.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001942479.1 TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: cph:Cpha266_2028 RNA polymerase, sigma 32 subunit, RpoH YP_001942480.1 PFAM: protein of unknown function DUF62; KEGG: cph:Cpha266_2027 protein of unknown function DUF62 YP_001942481.1 PFAM: permease YjgP/YjgQ family protein; KEGG: cph:Cpha266_2026 permease YjgP/YjgQ family protein YP_001942482.1 PFAM: peptidase M16 domain protein; KEGG: cph:Cpha266_2025 peptidase M16 domain protein YP_001942483.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001942484.1 KEGG: plt:Plut_0392 metal dependent phosphohydrolase; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase HD region YP_001942485.1 PFAM: LemA family protein; KEGG: cph:Cpha266_2022 LemA family protein YP_001942486.1 PFAM: protein of unknown function DUF477; KEGG: cph:Cpha266_2021 protein of unknown function DUF477 YP_001942487.1 PFAM: protein of unknown function DUF477; KEGG: cph:Cpha266_2020 protein of unknown function DUF477 YP_001942488.1 KEGG: cph:Cpha266_2019 hypothetical protein YP_001942489.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001942490.1 PFAM: cell divisionFtsK/SpoIIIE; SMART: AAA ATPase; KEGG: cph:Cpha266_2016 cell divisionFtsK/SpoIIIE YP_001942491.1 PFAM: nitrogen-fixing NifU domain protein; KEGG: plt:Plut_0398 NifU protein YP_001942492.1 PFAM: protein of unknown function DUF59; KEGG: cph:Cpha266_2014 protein of unknown function DUF59 YP_001942493.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001942494.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001942495.1 forms a direct contact with the tRNA during translation YP_001942496.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001942497.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001942498.1 Catalyzes the phosphorylation of UMP to UDP YP_001942499.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_001942500.1 PFAM: NUDIX hydrolase; KEGG: cph:Cpha266_0513 NUDIX hydrolase YP_001942501.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: cph:Cpha266_0514 major facilitator superfamily MFS_1 YP_001942502.1 PFAM: Hemolysin-type calcium-binding region; Alkaline phosphatase; metallophosphoesterase; Ig family protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: cch:Cag_0406 alkaline phosphatase YP_001942503.1 KEGG: mag:amb0666 hypothetical protein YP_001942504.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: cph:Cpha266_0749 cation diffusion facilitator family transporter YP_001942505.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cte:CT0576 NAD(P)-dependent cholesterol dehydrogenase YP_001942506.1 KEGG: cph:Cpha266_1269 cytochrome c, class I YP_001942507.1 KEGG: cph:Cpha266_1270 hypothetical protein YP_001942508.1 KEGG: gur:Gura_2922 transcriptional regulator YP_001942509.1 KEGG: cph:Cpha266_1438 hypothetical protein YP_001942510.1 TIGRFAM: CRISPR-associated protein Cas6; PFAM: protein of unknown function DUF57; KEGG: cph:Cpha266_2044 CRISPR-associated protein Cas6 YP_001942511.1 KEGG: sfu:Sfum_3180 hypothetical protein YP_001942512.1 KEGG: cph:Cpha266_0283 hypothetical protein YP_001942513.1 TIGRFAM: CRISPR-associated CXXC_CXXC protein Cst1; PFAM: CRISPR-associated protein CXXC_CXXC region; KEGG: msi:Msm_0169 predicted CRISPR-associated protein YP_001942514.1 TIGRFAM: CRISPR-associated autoregulator DevR family; CRISPR-associated regulatory protein, DevR family; KEGG: mac:MA3667 hypothetical protein YP_001942515.1 TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: mba:Mbar_A0308 hypothetical protein YP_001942516.1 KEGG: mba:Mbar_A0309 hypothetical protein; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001942517.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: protein of unknown function DUF48; KEGG: fnu:FN1177 hypothetical protein YP_001942518.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; KEGG: tma:TM1796 hypothetical protein YP_001942519.1 TIGRFAM: CRISPR-associated protein Cas4; PFAM: protein of unknown function DUF83; KEGG: pgi:PG2015 CRISPR-associated protein Cas4 YP_001942520.1 KEGG: cph:Cpha266_2380 hypothetical protein YP_001942522.1 KEGG: cph:Cpha266_2381 hypothetical protein YP_001942523.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; KEGG: cph:Cpha266_2382 hypothetical protein YP_001942524.1 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis YP_001942525.1 KEGG: cph:Cpha266_1809 metal dependent phosphohydrolase YP_001942526.1 PFAM: protein of unknown function DUF1003; KEGG: plt:Plut_1664 hypothetical protein YP_001942527.1 TIGRFAM: excinuclease ABC subunit A; PFAM: ABC transporter; KEGG: cph:Cpha266_0517 excinuclease ABC subunit A YP_001942529.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001942530.1 PFAM: inner-membrane translocator; KEGG: cph:Cpha266_0519 inner-membrane translocator YP_001942531.1 PFAM: ThiJ/PfpI domain protein; KEGG: cph:Cpha266_0520 isoprenoid biosynthesis protein with amidotransferase-like domain YP_001942532.1 KEGG: cph:Cpha266_0523 hypothetical protein YP_001942533.1 KEGG: cph:Cpha266_0524 hypothetical protein YP_001942534.1 PFAM: isochorismatase hydrolase; KEGG: cph:Cpha266_0525 isochorismatase hydrolase YP_001942535.1 KEGG: cph:Cpha266_0526 lipid-A-disaccharide synthase; TIGRFAM: tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide-1-P 4'-kinase YP_001942536.1 PFAM: protein of unknown function DUF374; KEGG: cph:Cpha266_0527 protein of unknown function DUF374 YP_001942537.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001942538.1 KEGG: cph:Cpha266_0529 hypothetical protein YP_001942539.1 PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: cph:Cpha266_0530 carbamoyl-phosphate synthase large subunit YP_001942540.1 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water YP_001942541.1 PFAM: ribulose-phosphate 3-epimerase; KEGG: cph:Cpha266_0532 ribulose-5-phosphate 3-epimerase YP_001942542.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: cph:Cpha266_0533 surface antigen (D15) YP_001942543.1 KEGG: plt:Plut_1647 hypothetical protein YP_001942544.1 PFAM: Peptidase M23; KEGG: cph:Cpha266_0535 peptidase M23B YP_001942545.1 KEGG: cph:Cpha266_0536 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein class 2 YP_001942546.1 PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cph:Cpha266_0537 prephenate dehydratase YP_001942547.1 PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein YP_001942548.1 KEGG: cph:Cpha266_0539 crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC YP_001942549.1 PFAM: CDP-alcohol phosphatidyltransferase; KEGG: pvi:Cvib_1430 CDP-alcohol phosphatidyltransferase YP_001942550.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: pmt:PMT0296 TPR repeat YP_001942551.1 alkyl hydroperoxidase; catalyze the reduction of hydrogen peroxide to water and the reduction of alkyl hydroperoxides to the corresponding alcohols YP_001942552.1 PFAM: ferric-uptake regulator; KEGG: cph:Cpha266_1963 ferric uptake regulator, Fur family YP_001942553.1 KEGG: plt:Plut_2079 Fibrobacter succinogenes major paralogous domain YP_001942554.1 KEGG: cph:Cpha266_1962 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonuclease; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B OB region domain; SMART: Cold shock protein YP_001942555.1 PFAM: glutamine amidotransferase class-I; KEGG: cph:Cpha266_1960 glutamine amidotransferase class-I YP_001942556.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cph:Cpha266_1957 multi-sensor hybrid histidine kinase YP_001942557.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: cph:Cpha266_1956 hypothetical protein YP_001942559.1 SMART: Rhodanese domain protein; KEGG: pvi:Cvib_0577 rhodanese domain protein YP_001942562.1 KEGG: rso:RS02604 HNS-like transcription regulator protein YP_001942563.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001942564.1 KEGG: cph:Cpha266_1942 hypothetical protein YP_001942565.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_1941 alpha/beta hydrolase fold YP_001942566.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: plt:Plut_0538 hypothetical protein YP_001942567.1 TIGRFAM: excinuclease ABC subunit A; PFAM: ABC transporter; KEGG: cph:Cpha266_1939 excinuclease ABC subunit A YP_001942568.1 KEGG: pvi:Cvib_0584 hypothetical protein YP_001942569.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001942570.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001942571.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: plt:Plut_0543 ExsB YP_001942572.1 PFAM: Abortive infection protein; KEGG: cph:Cpha266_1934 abortive infection protein YP_001942573.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001942574.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1932 glycosyl transferase, family 2 YP_001942575.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KEGG: pvi:Cvib_0591 NAD-dependent epimerase/dehydratase YP_001942576.1 PFAM: cyclase/dehydrase; KEGG: cph:Cpha266_1930 cyclase/dehydrase YP_001942577.1 PFAM: thioesterase superfamily protein; KEGG: cph:Cpha266_1929 thioesterase superfamily protein YP_001942578.1 KEGG: mfa:Mfla_1836 hypothetical protein YP_001942579.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: cph:Cpha266_1928 protein of unknown function DUF306, MetA and HslJ YP_001942580.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: cph:Cpha266_1368 Na+/Ca+ antiporter, CaCA family YP_001942581.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP YP_001942582.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_0799 glycosyl transferase, group 1 YP_001942583.1 KEGG: plt:Plut_0553 cell shape determining protein MreB/Mrl; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl; SMART: actin/actin family protein YP_001942584.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001942585.1 TIGRFAM: S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; KEGG: pvi:Cvib_0597 queuosine biosynthesis protein YP_001942586.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001942590.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: neu:NE1339 H-NS histone family YP_001942591.1 PFAM: Auxin Efflux Carrier; KEGG: cph:Cpha266_0806 auxin efflux carrier YP_001942592.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001942593.1 PFAM: Peptidase M23; KEGG: cph:Cpha266_0808 peptidase M23B YP_001942594.1 KEGG: plt:Plut_0563 hypothetical protein YP_001942595.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001942596.1 KEGG: pvi:Cvib_1210 L-aspartate oxidase; TIGRFAM: L-aspartate oxidase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein YP_001942597.1 PFAM: SNARE associated Golgi protein; KEGG: cph:Cpha266_0812 DedA family protein YP_001942598.1 PvlArgDC; converts arginine to agmatine and carbon dioxide; has a role in polyamine metabolism; in Methanococcus jannaschii this enzyme self-cleaves at serine-serine bond to form alpha (N-terminal) and beta (C-terminal) subunits; the alpha subunit contains a catalytically active pyruvoyl group; the beta subunit contains the substrate-binding residues; forms homotrimers of the alpha/beta complex YP_001942599.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001942600.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001942601.1 PFAM: FAD linked oxidase domain protein; KEGG: cph:Cpha266_0816 FAD linked oxidase domain protein YP_001942602.1 KEGG: cph:Cpha266_0817 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain YP_001942603.1 KEGG: cph:Cpha266_0818 hypothetical protein YP_001942604.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001942605.1 PFAM: chaperonin Cpn10; KEGG: cph:Cpha266_0820 chaperonin Cpn10 YP_001942606.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001942607.1 KEGG: cph:Cpha266_0822 hypothetical protein YP_001942608.1 PFAM: pentapeptide repeat protein; KEGG: cph:Cpha266_0823 pentapeptide repeat protein YP_001942610.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001942611.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_1781 cell division ATP-binding protein FtsE YP_001942612.1 KEGG: cph:Cpha266_1780 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA YP_001942613.1 KEGG: cph:Cpha266_1779 hypothetical protein YP_001942614.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_2529 tetratricopeptide TPR_2 repeat protein YP_001942615.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1251 DEAD/DEAH box helicase domain protein YP_001942616.1 KEGG: cph:Cpha266_1506 hypothetical protein YP_001942617.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: cch:Cag_1115 3-deoxy-D-manno-octulosonic-acid transferase YP_001942618.1 PFAM: UvrD/REP helicase; KEGG: cph:Cpha266_0674 ATP-dependent DNA helicase PcrA YP_001942619.1 KEGG: cph:Cpha266_0675 hypothetical protein YP_001942620.1 PFAM: nitroreductase; KEGG: cph:Cpha266_0676 nitroreductase YP_001942621.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001942622.1 KEGG: cph:Cpha266_0678 arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001942623.1 KEGG: cph:Cpha266_0679 enoyl-[acyl-carrier-protein] reductase [NADH] YP_001942624.1 KEGG: cph:Cpha266_0680 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent monomeric type YP_001942625.1 KEGG: cph:Cpha266_0681 hypothetical protein YP_001942626.1 PFAM: pirin; KEGG: cph:Cpha266_0684 pirin domain protein domain protein YP_001942627.1 PFAM: metallophosphoesterase; KEGG: cph:Cpha266_0685 metallophosphoesterase YP_001942628.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001942629.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: cph:Cpha266_0687 single-stranded-DNA-specific exonuclease RecJ YP_001942630.1 catalyzes the zinc dependent deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis and catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP in fatty acid biosynthesis YP_001942631.1 KEGG: cph:Cpha266_0542 ABC-type branched-chain amino acid transport systems periplasmic component-like YP_001942632.1 PFAM: inositol monophosphatase; KEGG: cph:Cpha266_0543 inositol-phosphate phosphatase YP_001942633.1 PFAM: TspO/MBR family protein; KEGG: cph:Cpha266_0544 TspO and MBR like proteins YP_001942634.1 KEGG: cph:Cpha266_0295 hypothetical protein YP_001942635.1 KEGG: mbu:Mbur_0296 hypothetical protein YP_001942636.1 KEGG: ppr:PBPRA1532 hypothetical protein YP_001942637.1 KEGG: cbe:Cbei_2837 plasmid pRiA4b ORF-3 family protein YP_001942638.1 KEGG: cch:Cag_0270 hypothetical protein YP_001942639.1 KEGG: cch:Cag_0271 hypothetical protein YP_001942641.1 KEGG: sdn:Sden_3581 hypothetical protein YP_001942642.1 PFAM: Domain of unknown function DUF1863; KEGG: neu:NE2099 hypothetical protein YP_001942644.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001942645.1 PFAM: Patatin; KEGG: mab:MAB_2091 hypothetical protein similar to patatin YP_001942646.1 KEGG: noc:Noc_0920 superfamily I DNA and RNA helicases and helicase subunits-like YP_001942647.1 KEGG: cph:Cpha266_1695 hypothetical protein YP_001942648.1 KEGG: amr:AM1_4420 esterase YP_001942650.1 KEGG: gur:Gura_0605 hypothetical protein YP_001942651.1 KEGG: sus:Acid_3466 hypothetical protein YP_001942652.1 KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001942653.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: pmt:PMT0296 TPR repeat YP_001942654.1 SMART: HNH nuclease; KEGG: aau:AAur_1020 HNH endonuclease domain protein YP_001942655.1 KEGG: sus:Acid_3466 hypothetical protein YP_001942656.1 KEGG: plt:Plut_0648 hypothetical protein YP_001942657.1 PFAM: helix-turn-helix domain protein; KEGG: plt:Plut_0647 XRE family transcriptional regulator YP_001942658.1 TIGRFAM: addiction module component, TIGR02574 family; PFAM: addiction module component CHP02574 family protein; KEGG: swo:Swol_1551 hypothetical protein YP_001942659.1 KEGG: cph:Cpha266_0774 hypothetical protein YP_001942660.1 PFAM: 3-demethylubiquinone-9 3-methyltransferase; KEGG: gur:Gura_0848 3-demethylubiquinone-9 3-methyltransferase YP_001942661.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: net:Neut_1850 glyoxalase/bleomycin resistance protein/dioxygenase YP_001942662.1 KEGG: cph:Cpha266_0282 ferredoxin, 2Fe-2S YP_001942663.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001942664.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001942665.1 KEGG: cph:Cpha266_0552 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH type 1 domain protein; Exoribonuclease, phosphorolytic domain 2; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; SMART: KH domain protein YP_001942666.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001942667.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: plt:Plut_1633 hypothetical protein YP_001942668.1 KEGG: cph:Cpha266_0555 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001942669.1 KEGG: cph:Cpha266_0556 Signal peptide peptidase A. Serine peptidase. MEROPS family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase S49 YP_001942670.1 KEGG: cph:Cpha266_0557 hypothetical protein YP_001942671.1 KEGG: cph:Cpha266_0558 Mg chelatase, subunit ChlI; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001942672.1 PFAM: phosphoenolpyruvate carboxylase; KEGG: cph:Cpha266_0559 phosphoenolpyruvate carboxylase YP_001942673.1 KEGG: cph:Cpha266_0560 photosystem P840 reaction center cytochrome c-551 YP_001942674.1 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis YP_001942675.1 PFAM: methyltransferase small; Methyltransferase type 12; KEGG: cph:Cpha266_0562 methyltransferase type 12 YP_001942676.1 KEGG: cph:Cpha266_0563 hypothetical protein YP_001942677.1 PFAM: integrase family protein; integrase; KEGG: cph:Cpha266_0564 tyrosine recombinase XerC subunit YP_001942678.1 TIGRFAM: ribosomal subunit interface protein; KEGG: cph:Cpha266_0565 hypothetical protein YP_001942679.1 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system YP_001942680.1 PFAM: extracellular solute-binding protein family 5; KEGG: cph:Cpha266_0567 extracellular solute-binding protein, family 5 YP_001942681.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: plt:Plut_1620 peptide ABC transporter, permease protein YP_001942682.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001942683.1 PFAM: hypothetical protein; Tetratricopeptide TPR_3; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_0570 tetratricopeptide TPR_2 repeat protein YP_001942684.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein YP_001942685.1 TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; KEGG: cph:Cpha266_0572 RNA methyltransferase, TrmH family, group 3 YP_001942686.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001942687.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein YP_001942688.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001942689.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: cph:Cpha266_0576 DNA repair protein RecN YP_001942690.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: cph:Cpha266_0577 twin-arginine translocation protein, TatA/E family subunit YP_001942691.1 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine YP_001942692.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: cph:Cpha266_0579 tRNA(Ile)-lysidine synthetase YP_001942693.1 KEGG: cph:Cpha266_0580 hypothetical protein YP_001942694.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001942695.1 required for 70S ribosome assembly YP_001942696.1 TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: cph:Cpha266_0583 bacteriochlorophyll/chlorophyll a synthase YP_001942697.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001942698.1 PFAM: creatinase; peptidase M24; KEGG: cph:Cpha266_0585 peptidase M24 YP_001942699.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: cph:Cpha266_0586 CutA1 divalent ion tolerance protein YP_001942700.1 KEGG: cph:Cpha266_0688 hypothetical protein YP_001942701.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_0689 glycosyl transferase, family 2 YP_001942702.1 PFAM: glycosyl transferase family 39; KEGG: cph:Cpha266_0690 glycosyl transferase, family 39 YP_001942703.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: cph:Cpha266_0691 phosphoesterase, PA-phosphatase related YP_001942704.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001942705.1 PFAM: Lipocalin-related protein and Bos/Can/Equ allergen; Lipocalin family protein; KEGG: pvi:Cvib_0516 lipocalin family protein YP_001942707.1 PFAM: hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: aci:ACIAD0355 hypothetical protein YP_001942708.1 PFAM: flavin reductase domain protein FMN-binding; KEGG: gme:Gmet_1443 flavin reductase-like, FMN-binding YP_001942709.1 KEGG: gur:Gura_2094 hypothetical protein YP_001942710.1 KEGG: gme:Gmet_1443 flavin reductase-like, FMN-binding YP_001942711.1 KEGG: cph:Cpha266_2523 type II site-specific deoxyribonuclease YP_001942712.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cph:Cpha266_2524 DNA methylase N-4/N-6 domain protein YP_001942713.1 KEGG: ade:Adeh_3278 hypothetical protein YP_001942715.1 KEGG: ppr:PBPRB1764 hypothetical protein YP_001942716.1 KEGG: aav:Aave_0556 hypothetical protein YP_001942717.1 KEGG: hch:HCH_04427 hypothetical protein YP_001942718.1 KEGG: psp:PSPPH_4543 hypothetical protein YP_001942719.1 KEGG: cch:Cag_1578 hypothetical protein YP_001942720.1 PFAM: protein of unknown function DUF891; KEGG: plt:Plut_0606 hypothetical protein YP_001942721.1 PFAM: twitching mobility protein PilT; KEGG: swo:Swol_1837 PilT protein-like protein YP_001942723.1 PFAM: protein of unknown function DUF486; KEGG: gsu:GSU1275 hypothetical protein YP_001942724.1 KEGG: cph:Cpha266_0697 ABC transporter, transmembrane region, type 1; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; PFAM: ABC transporter; SMART: AAA ATPase YP_001942725.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: cch:Cag_1270 thiamine biosynthesis protein ThiF YP_001942726.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001942727.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_001942728.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: cph:Cpha266_0731 thiamine biosynthesis protein ThiS YP_001942729.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: cph:Cpha266_0732 cystathionine gamma-synthase YP_001942730.1 KEGG: plt:Plut_1549 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001942731.1 KEGG: plt:Plut_1546 hypothetical protein YP_001942733.1 PFAM: MOSC domain containing protein; KEGG: cph:Cpha266_0733 MOSC domain containing protein YP_001942734.1 KEGG: cph:Cpha266_0734 GTP cyclohydrolase subunit MoaA; TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM domain protein; molybdenum cofactor synthesis domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001942735.1 TIGRFAM: molybdate transport repressor, ModE; PFAM: regulatory protein LysR; TOBE domain protein; KEGG: cph:Cpha266_0735 ModE family transcriptional regulator YP_001942736.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: plt:Plut_1542 transmembrane protein YP_001942737.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: cph:Cpha266_0441 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001942738.1 PFAM: TonB-dependent receptor; KEGG: cph:Cpha266_0440 TonB-dependent receptor YP_001942739.1 KEGG: cte:CT1541 ferredoxin, 2Fe-2S YP_001942740.1 KEGG: cph:Cpha266_0737 nitrogenase cofactor biosynthesis protein NifB; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001942741.1 PFAM: oxidoreductase/nitrogenase component 1; KEGG: cph:Cpha266_0738 nitrogenase YP_001942742.1 KEGG: plt:Plut_1533 nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: oxidoreductase/nitrogenase component 1 YP_001942743.1 KEGG: cph:Cpha266_0740 nitrogenase molybdenum-iron protein beta chain; TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: oxidoreductase/nitrogenase component 1 YP_001942744.1 KEGG: cph:Cpha266_0741 nitrogenase molybdenum-iron protein alpha chain; TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: oxidoreductase/nitrogenase component 1 YP_001942745.1 PFAM: nitrogen regulatory protein P-II; KEGG: cte:CT1535 nitrogen regulatory protein, P-II family YP_001942746.1 PFAM: nitrogen regulatory protein P-II; KEGG: cte:CT1534 nitrogen regulatory protein, P-II family YP_001942747.1 nitrogenase iron protein; nitrogenase component 2; with component 1, an molybdenum-iron protein, catalyzes the fixation of nitrogen to ammonia; nitrogen reductase provides electrons to the nitrogenase complex YP_001942749.1 PFAM: aldo/keto reductase; KEGG: cch:Cag_1232 aldo/keto reductase YP_001942750.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: gsu:GSU2314 sensory box histidine kinase/response regulator YP_001942751.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; GAF domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_1919 DNA-binding protein fis / Fis family transcriptional regulator YP_001942752.1 TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: cph:Cpha266_1918 homocitrate synthase YP_001942753.1 PFAM: Rhodanese domain protein; KEGG: cph:Cpha266_0124 rhodanese domain protein YP_001942754.1 TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; KEGG: cph:Cpha266_0126 hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) / cobyrinate a,c-diamide synthase YP_001942755.1 TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; KEGG: plt:Plut_0035 sulfite reductase, dissimilatory-type, gamma subunit YP_001942756.1 KEGG: cph:Cpha266_0128 sulfite reductase, dissimilatory-type alpha subunit; TIGRFAM: sulfite reductase, dissimilatory-type alpha subunit; PFAM: nitrite and sulphite reductase 4Fe-4S region YP_001942757.1 KEGG: cph:Cpha266_0129 sulfite reductase, dissimilatory-type beta subunit; TIGRFAM: sulfite reductase, dissimilatory-type beta subunit; PFAM: nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; nitrite and sulphite reductase 4Fe-4S region YP_001942758.1 unknown function YP_001942759.1 KEGG: cfa:610889 similar to collagen, type XXV, alpha 1 isoform 1 YP_001942760.1 KEGG: cph:Cpha266_0131 hypothetical protein YP_001942761.1 TIGRFAM: sulfur relay protein TusD/DsrE; PFAM: DsrE family protein; KEGG: cch:Cag_1952 DsrE protein YP_001942762.1 TIGRFAM: sulfur relay protein TusC/DsrF; PFAM: DsrE family protein; KEGG: cch:Cag_1951 DsrF protein YP_001942763.1 TIGRFAM: sulfur relay protein TusB/DsrH; PFAM: DsrH family protein; KEGG: cte:CT0857 DsrH protein YP_001942764.1 KEGG: cph:Cpha266_0135 hypothetical protein YP_001942765.1 PFAM: Nitrate reductase gamma subunit; KEGG: cph:Cpha266_0136 nitrate reductase, gamma subunit YP_001942766.1 KEGG: cph:Cpha266_0137 DsrK protein YP_001942767.1 KEGG: cph:Cpha266_0138 hypothetical protein YP_001942768.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_0139 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942769.1 PFAM: Polysulphide reductase NrfD; KEGG: cph:Cpha266_0140 polysulphide reductase, NrfD YP_001942770.1 TIGRFAM: siroheme synthase; KEGG: cte:CT2239 porphyrin biosynthesis protein YP_001942771.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cph:Cpha266_0142 uroporphyrinogen-III C-methyltransferase YP_001942772.1 KEGG: cch:Cag_1875 TPR repeat; TIGRFAM: pentatricopeptide repeat containing protein; PFAM: hypothetical protein; transcriptional regulator TrmB; SMART: AAA ATPase; Tetratricopeptide domain protein YP_001942773.1 KEGG: gvi:gll1120 unknown protein YP_001942778.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_2658 integrase, catalytic region YP_001942779.1 PFAM: IstB domain protein ATP-binding protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_2659 IstB domain protein ATP-binding protein YP_001942780.1 KEGG: cph:Cpha266_1578 protein of unknown function DUF1568 YP_001942781.1 KEGG: tbd:Tbd_0449 hypothetical protein YP_001942782.1 KEGG: cph:Cpha266_2116 hypothetical protein YP_001942783.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_1427 protein of unknown function DUF1568 YP_001942784.1 PFAM: thiol-disulphide oxidoreductase DCC; KEGG: cph:Cpha266_2114 thiol-disulphide oxidoreductase DCC YP_001942785.1 PFAM: RNA methylase; Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_2109 methyltransferase type 11 YP_001942786.1 TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: plasmid stabilization system; Addiction module toxin Txe/YoeB; KEGG: plt:Plut_1930 addiction module toxin, Txe/YoeB YP_001942787.1 KEGG: cch:Cag_0601 hypothetical protein YP_001942788.1 KEGG: plt:Plut_0829 Legionella vir region protein YP_001942790.1 PFAM: transglycosylase; KEGG: cph:Cpha266_1988 transglycosylase-associated protein YP_001942791.1 PFAM: transglutaminase domain protein; transglutaminase domain protein; KEGG: cph:Cpha266_1744 transglutaminase, N-terminal domain protein YP_001942792.1 PFAM: protein of unknown function DUF403; KEGG: cph:Cpha266_1743 protein of unknown function DUF403 YP_001942793.1 PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: cph:Cpha266_1742 protein of unknown function DUF404 YP_001942794.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1073 NADH dehydrogenase YP_001942795.1 TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: cph:Cpha266_0846 alpha-isopropylmalate/homocitrate synthase family transferase YP_001942796.1 TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: aconitate hydratase domain protein; KEGG: cph:Cpha266_0847 3-isopropylmalate dehydratase, small subunit YP_001942797.1 KEGG: cph:Cpha266_0848 homoaconitate hydratase family protein; TIGRFAM: homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: aconitate hydratase domain protein YP_001942798.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001942799.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001942800.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001942801.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: cph:Cpha266_0853 acetolactate synthase, large subunit YP_001942802.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001942803.1 PFAM: phosphatidate cytidylyltransferase; protein of unknown function DUF92 transmembrane; KEGG: cph:Cpha266_0855 protein of unknown function DUF92, transmembrane YP_001942804.1 TIGRFAM: protein TolQ; PFAM: MotA/TolQ/ExbB proton channel; KEGG: cph:Cpha266_0856 MotA/TolQ/ExbB proton channel YP_001942805.1 TIGRFAM: protein TolR; PFAM: Biopolymer transport protein ExbD/TolR; KEGG: plt:Plut_0612 ExbD/TolR family protein YP_001942806.1 TIGRFAM: TonB family protein; KEGG: cph:Cpha266_0858 Fis family transcriptional regulator YP_001942807.1 TIGRFAM: Tol-Pal system beta propeller repeat protein TolB; PFAM: TolB domain protein; WD40 domain protein beta Propeller; KEGG: cph:Cpha266_0859 WD40 domain protein beta propeller YP_001942808.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: cph:Cpha266_0860 OmpA/MotB domain protein YP_001942809.1 TIGRFAM: peptidoglycan-associated lipoprotein; PFAM: OmpA/MotB domain protein; KEGG: plt:Plut_0616 peptidoglycan-associated lipoprotein YP_001942810.1 TIGRFAM: tol-pal system protein YbgF; KEGG: cph:Cpha266_0862 membrane lipoprotein lipid attachment site YP_001942811.1 KEGG: cph:Cpha266_0316 hypothetical protein YP_001942812.1 PFAM: FeoA family protein; KEGG: pvi:Cvib_0519 FeoA family protein YP_001942813.1 PFAM: FeoA family protein; KEGG: cph:Cpha266_0318 FeoA family protein YP_001942814.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; Miro domain protein; KEGG: pvi:Cvib_0521 ferrous iron transport protein B YP_001942815.1 KEGG: cph:Cpha266_0322 hypothetical protein YP_001942816.1 KEGG: cph:Cpha266_0323 hypothetical protein YP_001942817.1 TIGRFAM: flavodoxin; PFAM: flavodoxin/nitric oxide synthase; KEGG: cph:Cpha266_0324 flavodoxin YP_001942818.1 KEGG: cph:Cpha266_0863 photosystem P840 reaction center protein PscD YP_001942819.1 PFAM: UMUC domain protein DNA-repair protein; KEGG: cph:Cpha266_1031 DNA-directed DNA polymerase YP_001942820.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001942821.1 PFAM: heat shock protein Hsp20; KEGG: plt:Plut_0622 heat shock protein, HSP20 family YP_001942822.1 PFAM: regulatory protein ArsR; KEGG: plt:Plut_0623 ArsR family transcriptional regulator YP_001942823.1 KEGG: cph:Cpha266_0867 transmembrane anti-sigma factor YP_001942824.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001942825.1 PFAM: amine oxidase; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cch:Cag_1888 carotenoid isomerase YP_001942826.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: cph:Cpha266_0875 L-alanine dehydrogenase YP_001942827.1 PFAM: ferredoxin; KEGG: cte:CT0651 chlorosome envelope protein J YP_001942828.1 PFAM: ferredoxin; KEGG: cph:Cpha266_0877 ferredoxin YP_001942829.1 KEGG: cph:Cpha266_0878 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001942830.1 KEGG: cph:Cpha266_0879 oligopeptide/dipeptide ABC transporter, ATPase subunit; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter; Oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase YP_001942831.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cph:Cpha266_0880 two component transcriptional regulator, winged helix family YP_001942832.1 KEGG: cph:Cpha266_0881 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001942833.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pvi:Cvib_1145 MscS mechanosensitive ion channel YP_001942834.1 PFAM: NUDIX hydrolase; KEGG: cph:Cpha266_0883 NUDIX hydrolase YP_001942835.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_0884 redoxin domain protein YP_001942836.1 PFAM: protein of unknown function DUF179; KEGG: cph:Cpha266_0885 protein of unknown function DUF179 YP_001942837.1 KEGG: cte:CT0686 hypothetical protein YP_001942838.1 KEGG: ppd:Ppro_1272 hypothetical protein YP_001942839.1 KEGG: cph:Cpha266_1446 hypothetical protein YP_001942840.1 KEGG: cph:Cpha266_1445 hypothetical protein YP_001942841.1 KEGG: cph:Cpha266_1444 hypothetical protein YP_001942842.1 KEGG: cch:Cag_0844 hypothetical protein YP_001942843.1 KEGG: gur:Gura_2921 hypothetical protein YP_001942844.1 PFAM: AAA-4 family protein; KEGG: gur:Gura_2922 transcriptional regulator YP_001942845.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001942846.1 KEGG: dde:Dde_0697 response regulator receiver domain protein (CheY-like) YP_001942847.1 KEGG: cch:Cag_0844 hypothetical protein YP_001942848.1 KEGG: cph:Cpha266_1517 conserved hypothetical cytosolic protein YP_001942849.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cph:Cpha266_1518 DNA methylase N-4/N-6 domain protein YP_001942850.1 TIGRFAM: peptide chain release factor 3; small GTP-binding protein; PFAM: protein synthesis factor GTP-binding; KEGG: cph:Cpha266_1177 bacterial peptide chain release factor 3 (bRF-3) YP_001942851.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: cte:CT0822 sodium:alanine symporter family protein YP_001942852.1 PFAM: Inorganic pyrophosphatase; KEGG: cph:Cpha266_1182 inorganic diphosphatase YP_001942853.1 PFAM: protein of unknown function DUF344; KEGG: plt:Plut_1276 hypothetical protein YP_001942854.1 TIGRFAM: fumarate hydratase, class II; PFAM: fumarate lyase; KEGG: cph:Cpha266_1185 fumarate hydratase, class II YP_001942855.1 TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: cph:Cpha266_1186 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001942856.1 PFAM: N-acetylneuraminic acid synthase domain; KEGG: cte:CT0825 sialic acid synthase YP_001942857.1 KEGG: yli:YALI0D24365g hypothetical protein YP_001942858.1 KEGG: cph:Cpha266_1026 hypothetical protein YP_001942859.1 molecular chaperone YP_001942860.1 PFAM: protein of unknown function DUF125 transmembrane; KEGG: cph:Cpha266_1189 protein of unknown function DUF125, transmembrane YP_001942861.1 KEGG: cph:Cpha266_1190 hypothetical protein YP_001942862.1 PFAM: UspA domain protein; KEGG: pvi:Cvib_1021 UspA domain protein YP_001942863.1 TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; Fe-S type hydro-lyase tartrate/fumarate beta region; KEGG: cph:Cpha266_1191 fumarase YP_001942865.1 KEGG: cph:Cpha266_2139 transposase and inactivated derivatives YP_001942866.1 KEGG: plt:Plut_1268 sodium pump decarboxylase, gamma subunit YP_001942867.1 PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: plt:Plut_1267 oxaloacetate decarboxylase, alpha subunit YP_001942868.1 KEGG: plt:Plut_1266 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit YP_001942869.1 KEGG: cph:Cpha266_1193 internalin-related protein YP_001942870.1 PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; KEGG: cph:Cpha266_1194 kojibiose phosphorylase YP_001942871.1 KEGG: cph:Cpha266_1195 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein YP_001942872.1 TIGRFAM: thioredoxin; PFAM: Redoxin domain protein; Thioredoxin domain; KEGG: plt:Plut_1261 thioredoxin YP_001942873.1 KEGG: plt:Plut_1260 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein YP_001942874.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pvi:Cvib_0749 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942875.1 KEGG: pvi:Cvib_1008 hypothetical protein YP_001942876.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: pvi:Cvib_1007 tRNA guanosine-2'-O-methyltransferase YP_001942877.1 PFAM: metallophosphoesterase; KEGG: cph:Cpha266_1199 hypothetical protein YP_001942878.1 KEGG: cph:Cpha266_1201 hypothetical protein YP_001942879.1 KEGG: cph:Cpha266_1202 hypothetical protein YP_001942880.1 KEGG: gfo:GFO_0037 membrane protein containing adenylate/guanylate cyclase catalytic domain YP_001942881.1 PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: fjo:Fjoh_4928 metal dependent phosphohydrolase YP_001942882.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: gfo:GFO_3394 secreted PAP2 superfamily protein YP_001942883.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cph:Cpha266_1237 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001942884.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_1238 methyltransferase type 11 YP_001942885.1 PFAM: thioesterase superfamily protein; KEGG: cch:Cag_0621 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_001942886.1 PFAM: protein of unknown function DUF814; KEGG: cph:Cpha266_0942 protein of unknown function DUF814 YP_001942887.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: plt:Plut_0726 deoxycytidylate deaminase YP_001942888.1 KEGG: cph:Cpha266_0944 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase zinc-binding; bifunctional deaminase-reductase domain protein YP_001942889.1 PFAM: DoxX family protein; KEGG: pvi:Cvib_1104 DoxX family protein YP_001942890.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: cph:Cpha266_0947 ErfK/YbiS/YcfS/YnhG family protein YP_001942891.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_001942892.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: cph:Cpha266_0951 alpha amylase, catalytic region YP_001942893.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001942894.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: pvi:Cvib_1101 recombination factor protein RarA YP_001942895.1 PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0954 outer membrane efflux protein YP_001942896.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_0955 methyltransferase type 12 YP_001942897.1 PFAM: histidine triad (HIT) protein; KEGG: cph:Cpha266_0956 histidine triad (HIT) protein YP_001942898.1 KEGG: cph:Cpha266_0957 hypothetical protein YP_001942899.1 PFAM: ferrochelatase; KEGG: pvi:Cvib_1096 ferrochelatase YP_001942900.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_0959 hypothetical protein YP_001942901.1 KEGG: pvi:Cvib_1094 hypothetical protein YP_001942902.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 3; KEGG: cte:CT0766 NADH dehydrogenase I, subunit 3 YP_001942903.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_001942904.1 TIGRFAM: NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH dehydrogenase (ubiquinone) 30 kDa subunit; KEGG: cph:Cpha266_0963 NADH (or F420H2) dehydrogenase, subunit C YP_001942905.1 PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: cph:Cpha266_0964 NADH dehydrogenase (ubiquinone) YP_001942906.1 PFAM: respiratory-chain NADH dehydrogenase subunit 1; KEGG: pvi:Cvib_1089 respiratory-chain NADH dehydrogenase, subunit 1 YP_001942907.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pvi:Cvib_1088 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001942908.1 PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6; KEGG: pvi:Cvib_1087 NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 YP_001942909.1 PFAM: NADH-ubiquinone oxidoreductase chain 4L; KEGG: cph:Cpha266_0968 NADH-ubiquinone oxidoreductase, chain 4L YP_001942910.1 KEGG: cph:Cpha266_0969 proton-translocating NADH-quinone oxidoreductase, chain L; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L; PFAM: NADH-Ubiquinone oxidoreductase (complex I) chain 5/L domain protein; NADH/Ubiquinone/plastoquinone (complex I) YP_001942911.1 KEGG: cph:Cpha266_0970 proton-translocating NADH-quinone oxidoreductase, chain M; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001942912.1 KEGG: cph:Cpha266_0971 proton-translocating NADH-quinone oxidoreductase, chain N; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N; PFAM: NADH/Ubiquinone/plastoquinone (complex I) YP_001942913.1 KEGG: cph:Cpha266_0972 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Nickel-iron dehydrogenase small subunit domain protein YP_001942914.1 PFAM: nickel-dependent hydrogenase large subunit; KEGG: cph:Cpha266_0973 nickel-dependent hydrogenase, large subunit YP_001942915.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: cph:Cpha266_0974 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001942916.1 TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: cph:Cpha266_0975 hydrogenase maturation protease YP_001942917.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001942918.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_0977 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001942919.1 PFAM: OsmC family protein; KEGG: cph:Cpha266_1720 OsmC family protein YP_001942920.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pvi:Cvib_1080 thioredoxin YP_001942921.1 PFAM: peptidase membrane zinc metallopeptidase KEGG: pvi:Cvib_1043 peptidase, membrane zinc metallopeptidase YP_001942922.1 PFAM: peptidase S14 ClpP; protein of unknown function DUF107; KEGG: cph:Cpha266_1160 nodulation efficiency protein NfeD YP_001942923.1 PFAM: hypothetical protein; KEGG: plt:Plut_1305 hypothetical protein YP_001942924.1 PFAM: UspA domain protein; KEGG: plt:Plut_1294 universal stress protein family YP_001942925.1 functions in transport of arginine/ornithine; inner membrane ATPase that cleaves ATP and phosphorylates two periplasmic proteins that function as two distinct transport systems, the AO (arginine and ornithine) and LAO (lysine, arginine, and ornithine) periplasmic binding proteins YP_001942926.1 MDM; functions in conversion of succinate to propionate YP_001942927.1 PFAM: methylmalonyl-CoA mutase; KEGG: cph:Cpha266_1165 methylmalonyl-CoA mutase YP_001942928.1 KEGG: cph:Cpha266_1166 acetyl-CoA carboxylase alpha subunit-like YP_001942929.1 TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cph:Cpha266_1167 methylmalonyl-CoA epimerase YP_001942930.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_1168 AMP-dependent synthetase and ligase YP_001942931.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001942932.1 PFAM: transketolase; transketolase; KEGG: cph:Cpha266_1170 transketolase subunit B YP_001942933.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1171 conserved hypothetical protein 103 YP_001942934.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001942935.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1173 zeta-carotene desaturase YP_001942937.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: cte:CT0815 copper-transporting ATPase, E1-E2 family YP_001942938.1 KEGG: cph:Cpha266_1806 serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; PFAM: transferase hexapeptide repeat containing protein; serine acetyltransferase domain protein YP_001942939.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001942940.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001942941.1 KEGG: cph:Cpha266_1803 hypothetical protein YP_001942942.1 PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1802 amine oxidase YP_001942943.1 PFAM: response regulator receiver; ATP-binding region ATPase domain protein; KEGG: cph:Cpha266_1801 integral membrane sensor hybrid histidine kinase YP_001942944.1 KEGG: plt:Plut_1434 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit YP_001942945.1 PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: plt:Plut_1433 biotin carboxyl carrier protein YP_001942946.1 KEGG: plt:Plut_1432 hypothetical protein YP_001942947.1 PFAM: carboxyl transferase; KEGG: plt:Plut_1431 propionyl-CoA carboxylase beta chain YP_001942948.1 KEGG: cte:CT1430 myo-inositol-1(or 4)-monophosphatase; TIGRFAM: histidinol-phosphate phosphatase; PFAM: inositol monophosphatase YP_001942949.1 KEGG: cph:Cpha266_1798 hypothetical protein YP_001942950.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: cph:Cpha266_1797 uroporphyrinogen-III synthase YP_001942951.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001942952.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001942953.1 PFAM: cytochrome c assembly protein; KEGG: plt:Plut_1425 HemX protein YP_001942954.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; KEGG: cph:Cpha266_1793 GTP-binding protein TypA YP_001942955.1 KEGG: cte:CT1423 chlorophyllide reductase, BchX subunit; TIGRFAM: chlorophyllide reductase iron protein subunit X; PFAM: NifH/frxC-family protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2 YP_001942956.1 TIGRFAM: chlorophyll synthesis pathway, BchC; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: cph:Cpha266_1791 chlorophyll synthesis pathway, BchC YP_001942957.1 PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: cph:Cpha266_1790 2-vinyl bacteriochlorophyllide hydratase YP_001942958.1 PFAM: extracellular solute-binding protein family 5; KEGG: cph:Cpha266_1789 extracellular solute-binding protein, family 5 YP_001942959.1 PFAM: glucose-inhibited division protein A; HI0933 family protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: aae:aq_500 thioredoxin reductase YP_001942960.1 PFAM: LmbE family protein; KEGG: cph:Cpha266_0824 LmbE family protein YP_001942961.1 KEGG: cph:Cpha266_0825 deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase YP_001942962.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; SMART: AAA ATPase; KEGG: plt:Plut_1417 two component transcriptional regulator, fis family YP_001942963.1 TIGRFAM: chlorosome envelope protein H; KEGG: cph:Cpha266_0826 chlorosome envelope protein H YP_001942965.1 KEGG: cph:Cpha266_1360 hypothetical protein YP_001942966.1 KEGG: cph:Cpha266_1359 hypothetical protein YP_001942968.1 KEGG: cph:Cpha266_1357 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001942969.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_1356 glycosyl transferase, group 1 YP_001942970.1 KEGG: cch:Cag_1041 hypothetical protein YP_001942972.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_0827 glycosyl transferase, family 2 YP_001942973.1 PFAM: Radical SAM domain protein; KEGG: cph:Cpha266_0829 radical SAM domain protein YP_001942974.1 PFAM: amine oxidase; KEGG: cte:CT1414 zeta-carotene desaturase YP_001942975.1 KEGG: cte:CT1413 hypothetical protein YP_001942976.1 PFAM: regulatory protein AsnC/Lrp family; regulatory protein MarR; KEGG: cph:Cpha266_0831 AsnC family transcriptional regulator YP_001942977.1 PFAM: glutamine synthetase catalytic region; KEGG: cph:Cpha266_0832 glutamine synthetase, catalytic region YP_001942978.1 PFAM: protein of unknown function UPF0047; KEGG: cph:Cpha266_0833 protein of unknown function UPF0047 YP_001942979.1 KEGG: cph:Cpha266_1156 short-chain dehydrogenase/reductase SDR YP_001942980.1 KEGG: cph:Cpha266_1487 protein of unknown function DUF1568 YP_001942981.1 KEGG: cte:CT0582 hypothetical protein YP_001942982.1 KEGG: dol:Dole_1478 hypothetical protein YP_001942983.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_1487 protein of unknown function DUF1568 YP_001942984.1 KEGG: gme:Gmet_1336 hypothetical protein YP_001942985.1 KEGG: cph:Cpha266_2054 CRISPR-associated protein Cas1 YP_001942986.1 TIGRFAM: CRISPR-associated protein Cas2; PFAM: protein of unknown function DUF196; KEGG: cph:Cpha266_2055 CRISPR-associated protein Cas2 YP_001942987.1 TIGRFAM: CRISPR-associated protein Cas1; PFAM: RNA-directed DNA polymerase (Reverse transcriptase); protein of unknown function DUF48; KEGG: cph:Cpha266_2054 CRISPR-associated protein Cas1 YP_001942988.1 TIGRFAM: CRISPR-associated RAMP protein, Cmr1 family; KEGG: pth:PTH_0707 hypothetical protein YP_001942989.1 PFAM: protein of unknown function DUF324; KEGG: mma:MM_3357 hypothetical protein YP_001942990.1 TIGRFAM: CRISPR-associated protein, Csx11 family; KEGG: rca:Rcas_4241 CRISPR-associated protein Csx11 YP_001942991.1 TIGRFAM: CRISPR-associated RAMP protein, Cmr4 family; PFAM: protein of unknown function DUF324; KEGG: pth:PTH_0712 hypothetical protein YP_001942992.1 KEGG: rrs:RoseRS_2588 hypothetical protein YP_001942993.1 KEGG: rca:Rcas_4238 hypothetical protein YP_001942994.1 KEGG: cbh:CLC_2119 hypothetical protein YP_001942995.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001942996.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1954 integrase, catalytic region YP_001942998.1 KEGG: cph:Cpha266_0834 hypothetical protein YP_001942999.1 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP YP_001943000.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001943001.1 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001943002.1 KEGG: cph:Cpha266_0838 helicase, RecD/TraA family; TIGRFAM: helicase, RecD/TraA family; PFAM: nucleic acid binding OB-fold tRNA/helicase-type; SMART: AAA ATPase YP_001943003.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_001943005.1 TIGRFAM: yecA family protein; KEGG: cch:Cag_0098 YgfB and YecA YP_001943006.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cph:Cpha266_0189 short-chain dehydrogenase/reductase SDR YP_001943007.1 PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: cph:Cpha266_0696 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein YP_001943008.1 PFAM: protein of unknown function DUF218; KEGG: cph:Cpha266_0844 protein of unknown function DUF218 YP_001943010.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1074 uncharacterised conserved protein UCP016719 YP_001943011.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001943012.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_001943013.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cte:CT0972 anti-anti-sigma factor YP_001943014.1 KEGG: cph:Cpha266_1081 tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase YP_001943015.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: cph:Cpha266_1082 maf protein YP_001943016.1 PFAM: Na+/solute symporter; KEGG: cph:Cpha266_1083 Na+/solute symporter YP_001943017.1 PFAM: PfkB domain protein; KEGG: cph:Cpha266_1084 PfkB domain protein YP_001943018.1 KEGG: cph:Cpha266_1085 alpha-amylase family protein YP_001943019.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001943020.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase catalytic; KEGG: cph:Cpha266_1087 lytic transglycosylase, catalytic YP_001943021.1 KEGG: cte:CT0980 ArsA ATPase family protein; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001943022.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001943023.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001943024.1 KEGG: cph:Cpha266_1091 hypothetical protein YP_001943025.1 KEGG: cph:Cpha266_1092 hypothetical protein YP_001943026.1 KEGG: cph:Cpha266_1093 hypothetical protein YP_001943027.1 PFAM: nitrogen regulatory protein P-II; KEGG: plt:Plut_1164 nitrogen regulatory protein P-II (GlnB, GlnK) YP_001943028.1 TIGRFAM: ammonium transporter; PFAM: Rh family protein/ammonium transporter; KEGG: plt:Plut_1163 ammonium transporter YP_001943029.1 KEGG: cph:Cpha266_1094 anti-sigma regulatory factor, serine/threonine protein kinase YP_001943030.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001943031.1 PFAM: ApbE family lipoprotein; KEGG: pvi:Cvib_0792 ApbE family lipoprotein YP_001943032.1 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved with K+ YP_001943033.1 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001943034.1 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001943035.1 PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: pvi:Cvib_1260 NADH dehydrogenase (quinone) YP_001943036.1 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali YP_001943037.1 PFAM: multiple resistance and pH regulation protein F; KEGG: pvi:Cvib_1262 multiple resistance and pH regulation protein F YP_001943038.1 TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; KEGG: pvi:Cvib_1263 monovalent cation/proton antiporter, MnhG/PhaG subunit YP_001943039.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: pvi:Cvib_0793 electron transport complex, RnfABCDGE type, A subunit YP_001943040.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001943041.1 TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein; KEGG: plt:Plut_1157 electron transport complex, RnfABCDGE type, G subunit YP_001943042.1 TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2 and RnfD family protein; KEGG: pvi:Cvib_0796 electron transport complex, RnfABCDGE type, D subunit YP_001943043.1 TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; KEGG: pvi:Cvib_0797 electron transport complex, RnfABCDGE type, C subunit YP_001943044.1 involved in the electron transport chain; in Methanosarcina acetivorans this protein is part of a cluster involved in electron transfer during growth on acetate YP_001943045.1 PFAM: Positive regulator of sigma(E) RseC/MucC; KEGG: pvi:Cvib_0799 hypothetical protein YP_001943046.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001943047.1 TIGRFAM: metal dependent phophohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: cte:CT0990 polyA polymerase family protein YP_001943048.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: cph:Cpha266_1110 oxidoreductase domain protein YP_001943049.1 PFAM: major facilitator superfamily MFS_1; KEGG: cph:Cpha266_1111 major facilitator superfamily MFS_1 YP_001943050.1 PFAM: periplasmic binding protein; KEGG: cch:Cag_0726 ABC transporter, periplasmic substrate-binding protein YP_001943051.1 PFAM: NUDIX hydrolase; KEGG: cch:Cag_0727 NUDIX/MutT family protein YP_001943052.1 KEGG: cch:Cag_1259 hypothetical protein YP_001943053.1 PFAM: helix-turn-helix domain protein; KEGG: cch:Cag_1260 XRE family transcriptional regulator YP_001943054.1 PFAM: cyclase/dehydrase; KEGG: cte:CT0933 hypothetical protein YP_001943055.1 PFAM: Na+/Picotransporter; KEGG: cph:Cpha266_1114 Na+/Pi-cotransporter YP_001943056.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: pca:Pcar_2970 TonB-dependent receptor protein YP_001943057.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cte:CT0409 ferredoxin, 4Fe-4S YP_001943058.1 PFAM: periplasmic binding protein; KEGG: cte:CT0410 iron(III) ABC transporter, periplasmic iron-binding protein YP_001943059.1 PFAM: transport system permease protein; KEGG: cte:CT0411 iron(III) ABC transporter, permease protein YP_001943060.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cte:CT0412 iron(III) ABC transporter, ATP-binding protein YP_001943061.1 KEGG: cte:CT0413 iron complex transport system substrate-binding protein YP_001943062.1 PFAM: protein of unknown function DUF105; KEGG: cte:CT0414 hypothetical protein YP_001943063.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cte:CT0415 carbon-nitrogen hydrolase family protein YP_001943064.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cte:CT0390 uroporphyrin-III C-methyltransferase YP_001943065.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; anaerobic cobalt chelatase; KEGG: cte:CT0389 cobalt chelatase CbiK YP_001943066.1 TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: cte:CT0388 precorrin-2 C20-methyltransferase YP_001943067.1 TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-8X methylmutase CbiC/CobH; KEGG: cte:CT0387 precorrin-3B C17-methyltransferase/precorrin-8X methylmutase YP_001943068.1 KEGG: cte:CT0386 precorrin-6y C5,15-methyltransferase, decarboxylating; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase YP_001943069.1 KEGG: cte:CT0385 precorrin-4 C11-methyltransferase/cobalamin biosynthesis protein; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein YP_001943070.1 PFAM: xylose isomerase; KEGG: cte:CT0416 hypothetical protein YP_001943071.1 PFAM: Radical SAM domain protein; KEGG: cte:CT0417 AslB/AtsB family protein YP_001943072.1 PFAM: CobN/magnesium chelatase; KEGG: cte:CT0418 cobalamin biosynthesis protein CobN YP_001943073.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: ppd:Ppro_1260 TonB-dependent receptor YP_001943074.1 KEGG: cte:CT0420 magnesium-chelatase, subunit D/I family; TIGRFAM: cobaltochelatase subunit; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; ATPase associated with various cellular activities AAA_5 YP_001943075.1 KEGG: cte:CT0421 magnesium-chelatase, subunit I family; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase YP_001943076.1 PFAM: CobN/magnesium chelatase; KEGG: cte:CT0422 CobN protein YP_001943077.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cte:CT0423 receptor YP_001943078.1 KEGG: cte:CT0413 iron complex transport system substrate-binding protein YP_001943079.1 KEGG: azo:azo3307 probable coenzyme A transferase; TIGRFAM: succinate CoA transferase; PFAM: acetyl-CoA hydrolase/transferase YP_001943080.1 PFAM: protein of unknown function DUF399; KEGG: bfs:BF3448 hypothetical protein YP_001943081.1 KEGG: cph:Cpha266_0191 hypothetical protein YP_001943082.1 KEGG: cph:Cpha266_2262 hypothetical protein YP_001943083.1 KEGG: cph:Cpha266_2261 DnaK like protein YP_001943084.1 PFAM: ATPase AAA; SMART: AAA ATPase; KEGG: cph:Cpha266_2260 AAA ATPase, central domain protein YP_001943085.1 PFAM: protein of unknown function DUF323; KEGG: cph:Cpha266_2259 protein of unknown function DUF323 YP_001943086.1 KEGG: cte:CT1578 integrase/recombinase-related protein YP_001943087.1 KEGG: azc:AZC_0339 hypothetical protein YP_001943088.1 KEGG: aeh:Mlg_0384 hypothetical protein YP_001943089.1 KEGG: mmw:Mmwyl1_1516 hypothetical protein YP_001943090.1 PFAM: Patatin; KEGG: hiq:CGSHiGG_03920 patatin YP_001943096.1 KEGG: cte:CT1927 hypothetical protein YP_001943097.1 KEGG: cph:Cpha266_2199 hypothetical protein YP_001943098.1 PFAM: HpcH/HpaI aldolase; KEGG: cph:Cpha266_2198 HpcH/HpaI aldolase YP_001943099.1 KEGG: cph:Cpha266_2231 hypothetical protein YP_001943100.1 TIGRFAM: prevent-host-death family protein; PFAM: protein of unknown function DUF172; KEGG: cph:Cpha266_2187 prevent-host-death family protein YP_001943101.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001943103.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: aba:Acid345_3867 lysine exporter protein (LysE/YggA) YP_001943104.1 KEGG: pnu:Pnuc_0548 hypothetical protein YP_001943105.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001943106.1 TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM domain protein; KEGG: pvi:Cvib_0808 anaerobic ribonucleoside-triphosphate reductase activating protein YP_001943107.1 KEGG: cph:Cpha266_0487 hypothetical protein YP_001943108.1 catalyzes the ATP-dependent transport of cobalt YP_001943109.1 periplasmic cobalt binding component of the cobalt transport system YP_001943110.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: cte:CT0392 cobalt transport protein YP_001943111.1 KEGG: cte:CT0391 cobalt transport protein; TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter; SMART: AAA ATPase YP_001943112.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cph:Cpha266_1115 TonB-dependent receptor YP_001943113.1 KEGG: cch:Cag_1013 nitroreductase family protein; TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase YP_001943114.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001943115.1 TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_1118 L-threonine O-3-phosphate decarboxylase YP_001943116.1 CobD; CbiD in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_001943117.1 TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; KEGG: cph:Cpha266_1120 cob(I)yrinic acid a,c-diamide adenosyltransferase YP_001943118.1 PFAM: transport system permease protein; KEGG: pvi:Cvib_0818 transport system permease protein YP_001943119.1 PFAM: SMC domain protein; ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_1122 ABC transporter YP_001943120.1 PFAM: xylose isomerase; KEGG: cch:Cag_1076 hypothetical protein YP_001943121.1 PFAM: Cna B domain protein; KEGG: plt:Plut_1105 hypothetical protein YP_001943122.1 KEGG: plt:Plut_1104 hypothetical protein YP_001943123.1 KEGG: plt:Plut_1095 hypothetical protein YP_001943124.1 KEGG: plt:Plut_1100 hypothetical protein YP_001943126.1 PFAM: cobalbumin biosynthesis protein; KEGG: cte:CT0945 cobalamin biosynthesis protein CobP YP_001943127.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001943128.1 PFAM: alpha/beta hydrolase fold; Ndr family protein; KEGG: cph:Cpha266_2528 alpha/beta hydrolase fold YP_001943129.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: cte:CT0948 cobalamin 5'-phosphate synthase YP_001943130.1 KEGG: cph:Cpha266_1560 hypothetical protein YP_001943131.1 KEGG: gfo:GFO_0848 two-component system sensor histidine kinase/response regulator hybrid; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein YP_001943132.1 KEGG: cph:Cpha266_1553 hypothetical protein YP_001943133.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1552 uncharacterised conserved protein UCP025560 YP_001943134.1 KEGG: cph:Cpha266_1551 hypothetical protein YP_001943135.1 KEGG: pvi:Cvib_0834 hypothetical protein YP_001943136.1 PFAM: small multidrug resistance protein; KEGG: gsu:GSU0708 multidrug resistance protein YP_001943137.1 KEGG: fal:FRAAL1779 integral membrane acyltransferase YP_001943138.1 KEGG: pde:Pden_2389 hypothetical protein YP_001943139.1 KEGG: cph:Cpha266_1345 hypothetical protein YP_001943140.1 KEGG: cph:Cpha266_0294 hypothetical protein YP_001943141.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: cte:CT1215 thioredoxin YP_001943142.1 KEGG: cph:Cpha266_0980 5 nucleotidase, deoxy, cytosolic type C YP_001943143.1 KEGG: pvi:Cvib_1062 hypothetical protein YP_001943144.1 PFAM: Protein of unknown function methylase SMART: PUA domain containing protein; KEGG: plt:Plut_1226 hypothetical protein YP_001943145.1 KEGG: cph:Cpha266_0982 hypothetical protein YP_001943146.1 PFAM: manganese and iron superoxide dismutase; KEGG: cte:CT1211 superoxide dismutase YP_001943147.1 KEGG: plt:Plut_1223 hypothetical protein YP_001943148.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001943149.1 PFAM: esterase; KEGG: cph:Cpha266_0986 esterase YP_001943150.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: cph:Cpha266_0987 sec-independent protein translocase TatC YP_001943151.1 PFAM: Polyprenyl synthetase; KEGG: cph:Cpha266_0988 trans-hexaprenyltranstransferase YP_001943152.1 PFAM: PASTA domain containing protein; KEGG: cph:Cpha266_0989 PASTA domain containing protein YP_001943153.1 KEGG: cch:Cag_1501 hypothetical protein YP_001943154.1 KEGG: plt:Plut_0918 hypothetical protein YP_001943155.1 PFAM: Chloride channel core; KEGG: cte:CT1391 chloride channel YP_001943156.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0993 ABC transporter YP_001943157.1 PFAM: Alcohol dehydrogenase GroES domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: cph:Cpha266_0994 alcohol dehydrogenase GroES domain protein YP_001943158.1 PFAM: membrane protein of unknown function; KEGG: cph:Cpha266_0995 membrane protein of unknown function YP_001943159.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001943160.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001943161.1 PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: plt:Plut_1144 alcohol dehydrogenase, zinc-containing YP_001943162.1 KEGG: pvi:Cvib_0811 anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; Glycosyl transferase, family 3-like YP_001943163.1 KEGG: cch:Cag_0780 hypothetical protein YP_001943164.1 TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: sigma-54 factor core-binding region; sigma-54 DNA-binding domain protein; KEGG: cph:Cpha266_1547 RNA polymerase, sigma 54 subunit, RpoN YP_001943165.1 heat shock protein involved in degradation of misfolded proteins YP_001943166.1 heat shock protein involved in degradation of misfolded proteins YP_001943167.1 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis YP_001943169.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: bvu:BVU_1231 TonB-dependent outer membrane receptor protein YP_001943170.1 KEGG: fjo:Fjoh_1367 phytase YP_001943171.1 PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: plt:Plut_1072 2-oxoacid:ferredoxin oxidoreductase, alpha subunit YP_001943172.1 TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: plt:Plut_1073 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate YP_001943173.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001943175.1 KEGG: cte:CT1775 hypothetical protein YP_001943176.1 PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: cte:CT1776 bacteriochlorophyll c3(1) hydratase YP_001943178.1 KEGG: cte:CT1002 hypothetical protein YP_001943179.1 PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; KEGG: cph:Cpha266_1068 pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001943180.1 TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: cte:CT0595 hypothetical protein YP_001943181.1 KEGG: cte:CT1238 hypothetical protein YP_001943182.1 TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase FAD-binding; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1066 geranylgeranyl reductase YP_001943184.1 KEGG: bbr:BB1527 hypothetical protein YP_001943185.1 KEGG: cph:Cpha266_1424 nitroreductase YP_001943186.1 PFAM: NUDIX hydrolase; KEGG: plt:Plut_1259 hypothetical protein YP_001943187.1 KEGG: cph:Cpha266_1686 hypothetical protein YP_001943188.1 KEGG: cph:Cpha266_1681 hypothetical protein YP_001943189.1 KEGG: cph:Cpha266_1976 hypothetical protein YP_001943190.1 KEGG: cph:Cpha266_1680 Pep581 peptidase. Metallo peptidase. MEROPS family M20C; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001943191.1 KEGG: plt:Plut_0470 hypothetical protein YP_001943192.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_001943193.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cph:Cpha266_1773 hypothetical protein YP_001943194.1 PFAM: protein of unknown function DUF134; KEGG: plt:Plut_0906 hypothetical protein YP_001943195.1 PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis protein; KEGG: cph:Cpha266_1457 dinitrogenase iron-molybdenum cofactor biosynthesis YP_001943196.1 TIGRFAM: methyltransferase; KEGG: bpd:BURPS668_A1051 IMP dehydrogenase/GMP reductase YP_001943197.1 PFAM: Rhodanese domain protein; KEGG: sru:SRU_0931 thiosulfate sulfurtransferase YP_001943198.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: cph:Cpha266_1977 NADH:flavin oxidoreductase/NADH oxidase YP_001943199.1 TIGRFAM: MIP family channel protein; PFAM: major intrinsic protein; KEGG: cph:Cpha266_1922 MIP family channel proteins YP_001943200.1 PFAM: zinc/iron permease; KEGG: cph:Cpha266_1456 zinc transporter ZupT YP_001943201.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1454 conserved hypothetical protein 730 YP_001943202.1 PFAM: glycosyl transferase family 2; KEGG: cte:CT1271 glycosyl transferase YP_001943203.1 TIGRFAM: bacteriochlorophyll/chlorophyll synthetase; PFAM: UbiA prenyltransferase; KEGG: cph:Cpha266_1449 bacteriochlorophyll/chlorophyll a synthase YP_001943205.1 KEGG: pvi:Cvib_0746 hypothetical protein YP_001943206.1 PFAM: GCN5-related N-acetyltransferase; KEGG: plt:Plut_0913 acetyltransferase, GNAT family YP_001943208.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: cph:Cpha266_1421 lysine exporter protein (LysE/YggA) YP_001943209.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: bba:Bd2628 hypothetical protein YP_001943210.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: plt:Plut_1216 ferredoxin, 4Fe-4S YP_001943211.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: pvi:Cvib_0369 radical SAM domain protein YP_001943212.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pvi:Cvib_0750 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001943213.1 PFAM: PhoH family protein; KEGG: cph:Cpha266_1415 PhoH family protein YP_001943214.1 TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; KEGG: cch:Cag_1084 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001943215.1 KEGG: cph:Cpha266_1413 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001943216.1 TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_1412 histidinol phosphate aminotransferase YP_001943217.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: cph:Cpha266_1411 tRNA/rRNA methyltransferase (SpoU) YP_001943218.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_1410 alpha/beta hydrolase fold YP_001943219.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001943220.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001943221.1 pyrophosphate-energized proton pump; pyrophosphate-energized inorganic pyrophosphatase; H+-PPase; can cleave pyrophosphate to two phosphates; can generate a proton motive force and drive pyrophosphate synthesis when PMF is sufficient YP_001943222.1 KEGG: cph:Cpha266_1023 mitomycin resistance protein YP_001943223.1 PFAM: Domain of unknown function DUF1848; KEGG: cph:Cpha266_1022 hypothetical protein YP_001943224.1 KEGG: ppg:PputGB1_4162 hypothetical protein YP_001943225.1 PFAM: protein of unknown function DUF156; KEGG: pap:PSPA7_4093 hypothetical protein YP_001943226.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: ppf:Pput_4528 cation diffusion facilitator family transporter YP_001943227.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: cph:Cpha266_1021 endonuclease/exonuclease/phosphatase YP_001943228.1 KEGG: cph:Cpha266_1020 hypothetical protein YP_001943229.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001943230.1 PFAM: SNARE associated Golgi protein; KEGG: cph:Cpha266_1018 DedA family protein YP_001943231.1 PFAM: transketolase; KEGG: cph:Cpha266_1017 transketolase subunit A YP_001943232.1 PFAM: Protein of unknown function methylase KEGG: cph:Cpha266_1016 conserved hypothetical protein 95 YP_001943233.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001943234.1 PFAM: aminotransferase class V; aminotransferase class I and II; KEGG: cph:Cpha266_1014 aminotransferase YP_001943235.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: cte:CT0967 hypothetical protein YP_001943236.1 PFAM: PSP1 domain protein; KEGG: cph:Cpha266_1012 PSP1 domain protein YP_001943237.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001943238.1 KEGG: pvi:Cvib_0835 hypothetical protein YP_001943239.1 PFAM: peptidase C14 caspase catalytic subunit p20; KEGG: cph:Cpha266_1254 peptidase C14, caspase catalytic subunit P20 YP_001943240.1 KEGG: cph:Cpha266_1255 UDP-N-acetylmuramate dehydrogenase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD linked oxidase domain protein; UDP-N-acetylenolpyruvoylglucosamine reductase domain protein YP_001943242.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: cch:Cag_1033 hydrogenase/sulfur reductase, gamma subunit YP_001943243.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1257 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001943244.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1258 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001943245.1 PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: cph:Cpha266_1259 methyl-viologen-reducing hydrogenase, delta subunit YP_001943246.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1260 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001943247.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cph:Cpha266_1261 CoB--CoM heterodisulfide reductase YP_001943248.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_001943249.1 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate YP_001943250.1 TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: protein of unknown function UPF0031; YjeF-family domain protein; KEGG: cph:Cpha266_1264 carbohydrate kinase, YjeF related protein YP_001943251.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001943252.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, there are paralogous proteins that have been found to be nonessential but do function in secretion of a subset of exported proteins YP_001943254.1 PFAM: 8-oxoguanine DNA glycosylase domain protein; SMART: HhH-GPD family protein; KEGG: cte:CT0996 8-oxoguanine DNA glycosylase YP_001943257.1 PFAM: NAD-dependent epimerase/dehydratase; KEGG: cch:Cag_1016 hypothetical protein YP_001943258.1 KEGG: pvi:Cvib_0856 hypothetical protein YP_001943259.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001943260.1 KEGG: cph:Cpha266_1568 hypothetical protein YP_001943261.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: pvi:Cvib_0632 3'(2'),5'-bisphosphate nucleotidase YP_001943262.1 KEGG: cph:Cpha266_1248 arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001943263.1 KEGG: cph:Cpha266_1304 C-terminal processing peptidase-1. Serine peptidase. MEROPS family S41A; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001943264.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: cph:Cpha266_1207 Na+/Ca+ antiporter, CaCA family YP_001943265.1 TIGRFAM: AbrB family transcriptional regulator; PFAM: SpoVT/AbrB domain protein; KEGG: cch:Cag_1078 AbrB family transcriptional regulator YP_001943267.1 KEGG: sbl:Sbal_0943 hypothetical protein YP_001943268.1 KEGG: cph:Cpha266_1691 hypothetical protein YP_001943269.1 PFAM: protein of unknown function DUF1499; KEGG: cph:Cpha266_0483 protein of unknown function DUF1499 YP_001943270.1 KEGG: cph:Cpha266_1229 succinylglutamate desuccinylase/aspartoacylase YP_001943271.1 KEGG: cph:Cpha266_1230 hypothetical protein YP_001943273.1 PFAM: protein of unknown function DUF477; KEGG: cch:Cag_1771 hypothetical protein YP_001943274.1 PFAM: protein of unknown function DUF477; KEGG: lbi:LEPBI_I3031 hypothetical protein YP_001943275.1 PFAM: ferredoxin-dependent glutamate synthase; Rieske [2Fe-2S] domain protein; KEGG: jan:Jann_3121 ferredoxin-dependent glutamate synthase YP_001943276.1 PFAM: peptidase M50; KEGG: cph:Cpha266_1573 peptidase M50 YP_001943277.1 PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: cph:Cpha266_1306 ATP citrate lyase subunit 2 YP_001943278.1 PFAM: ATP-grasp domain protein; KEGG: cph:Cpha266_1307 ATP citrate lyase subunit 1 YP_001943279.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001943280.1 PFAM: conserved hypothetical protein; KEGG: plt:Plut_1058 hypothetical protein YP_001943281.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: pvi:Cvib_0871 ABC transporter YP_001943282.1 KEGG: cte:CT1094 hypothetical protein YP_001943283.1 PFAM: protein of unknown function UPF0016; KEGG: cph:Cpha266_1312 protein of unknown function UPF0016 YP_001943284.1 PFAM: Lipocalin-related protein and Bos/Can/Equ allergen; Lipocalin family protein; KEGG: cph:Cpha266_1313 lipocalin family protein YP_001943285.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cph:Cpha266_1314 GCN5-related N-acetyltransferase YP_001943286.1 PFAM: Rubredoxin-type Fe(Cys)4 protein; KEGG: cph:Cpha266_1315 rubredoxin-type Fe(Cys)4 protein YP_001943287.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1316 protein of unknown function DUF214 YP_001943288.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1317 protein of unknown function DUF214 YP_001943289.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: plt:Plut_1051 diguanylate cyclase (GGDEF domain) YP_001943290.1 KEGG: cph:Cpha266_1319 phosphate-binding protein YP_001943291.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001943292.1 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate YP_001943293.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001943294.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001943295.1 PFAM: arginine repressor; KEGG: cph:Cpha266_1324 transcriptional regulator, ArgR family YP_001943296.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001943297.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001943298.1 KEGG: cph:Cpha266_1328 C-terminal processing peptidase-1. Serine peptidase. MEROPS family S41A; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001943299.1 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate YP_001943300.1 KEGG: cph:Cpha266_1330 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001943301.1 PFAM: helix-turn-helix domain protein; peptidase S24 and S26 domain protein; KEGG: pvi:Cvib_0894 prophage repressor YP_001943302.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_1487 protein of unknown function DUF1568 YP_001943303.1 PFAM: CBS domain containing protein; KEGG: cph:Cpha266_1331 CBS domain containing protein YP_001943304.1 KEGG: cph:Cpha266_1332 ribose-5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/galactose isomerase YP_001943305.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_001943306.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: cph:Cpha266_1334 5-formyltetrahydrofolate cyclo-ligase YP_001943307.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: cph:Cpha266_1335 fumarylacetoacetate (FAA) hydrolase YP_001943308.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001943309.1 KEGG: cph:Cpha266_1337 hypothetical protein YP_001943310.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: plt:Plut_1011 methyltransferase YP_001943311.1 KEGG: pvi:Cvib_0903 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001943312.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase KEGG: pvi:Cvib_0904 cyclic nucleotide-binding protein YP_001943313.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_1339 NAD-dependent epimerase/dehydratase YP_001943314.1 PFAM: basic membrane lipoprotein; KEGG: cph:Cpha266_1340 basic membrane lipoprotein YP_001943315.1 PFAM: CHAD domain containing protein; KEGG: cph:Cpha266_1341 CHAD domain containing protein YP_001943316.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cph:Cpha266_1342 cobyrinic acid a,c-diamide synthase YP_001943317.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cch:Cag_0383 oxidoreductase, short-chain dehydrogenase/reductase family YP_001943318.1 PFAM: peptidase M15D vanX D-ala-D-ala dipeptidase; peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; KEGG: cph:Cpha266_1343 peptidase M15D, VanX D-ala-D-ala dipeptidase YP_001943319.1 TIGRFAM: yecA family protein; KEGG: cph:Cpha266_0914 YecA family protein YP_001943320.1 PFAM: NLP/P60 protein; KEGG: plt:Plut_0897 NLP/P60 family protein YP_001943321.1 KEGG: plt:Plut_1030 hypothetical protein YP_001943322.1 PFAM: penicillin-binding protein transpeptidase; KEGG: psa:PST_2699 probable beta-lactamase YP_001943323.1 KEGG: cch:Cag_0509 hypothetical protein YP_001943324.1 KEGG: cph:Cpha266_2106 hypothetical protein YP_001943325.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: ppd:Ppro_3713 ABC transporter YP_001943326.1 PFAM: protein of unknown function DUF214; KEGG: gsu:GSU0948 ABC transporter, permease protein YP_001943327.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: afw:Anae109_1045 efflux transporter, RND family, MFP subunit YP_001943328.1 PFAM: outer membrane efflux protein; KEGG: gme:Gmet_3465 outer membrane efflux protein YP_001943329.1 PFAM: regulatory protein TetR; KEGG: ppd:Ppro_3852 TetR family transcriptional regulator YP_001943330.1 KEGG: plt:Plut_2079 Fibrobacter succinogenes major paralogous domain YP_001943331.1 KEGG: plt:Plut_0346 hypothetical protein YP_001943332.1 KEGG: plt:Plut_0345 hypothetical protein YP_001943333.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: plt:Plut_0344 two component transcriptional regulator, fis family YP_001943334.1 KEGG: plt:Plut_0343 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001943335.1 PFAM: cytochrome c class I; KEGG: cph:Cpha266_0171 C-type cytochrome YP_001943336.1 KEGG: cch:Cag_0441 hypothetical protein YP_001943337.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: cph:Cpha266_1205 two component transcriptional regulator, winged helix family YP_001943338.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cch:Cag_0439 periplasmic sensor signal transduction histidine kinase YP_001943339.1 KEGG: ter:Tery_2635 hypothetical protein YP_001943340.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1954 integrase, catalytic region YP_001943341.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001943342.1 KEGG: cch:Cag_1146 hypothetical protein YP_001943343.1 KEGG: pna:Pnap_4508 hypothetical protein YP_001943344.1 PFAM: plasmid stabilization system; KEGG: gvi:gsr3505 hypothetical protein YP_001943345.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: gvi:gsr2534 hypothetical protein YP_001943347.1 TIGRFAM: addiction module killer protein; PFAM: protein of unknown function DUF891; KEGG: dde:Dde_0501 hypothetical protein YP_001943348.1 TIGRFAM: addiction module antidote protein; KEGG: pvi:Cvib_0663 transcriptional regulator YP_001943349.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_2112 integrase, catalytic region YP_001943350.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001943351.1 TIGRFAM: outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta- domain protein; Haemagluttinin repeat-containing protein; KEGG: cph:Cpha266_1203 outer membrane autotransporter barrel domain YP_001943352.1 KEGG: cph:Cpha266_2139 transposase and inactivated derivatives YP_001943353.1 PFAM: Haemagluttinin domain protein; KEGG: rsp:RSP_4120 hypothetical protein YP_001943354.1 KEGG: ppd:Ppro_3601 transposase, IS4 family protein YP_001943355.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: hip:CGSHiEE_05405 Sel1 domain protein repeat-containing protein YP_001943356.1 KEGG: cph:Cpha266_1005 hypothetical protein YP_001943357.1 PFAM: cytochrome c biogenesis protein transmembrane region; Thioredoxin domain; KEGG: cte:CT1075 thiol:disulfide interchange protein DsbD YP_001943358.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_0469 redoxin domain protein YP_001943359.1 PFAM: Cupin 2 conserved barrel domain protein; KEGG: cph:Cpha266_1350 cupin 2, conserved barrel domain protein YP_001943360.1 PFAM: SMC domain protein; KEGG: cph:Cpha266_1354 SMC domain protein YP_001943361.1 PFAM: malic protein domain protein; malic protein NAD-binding; KEGG: plt:Plut_0896 malate dehydrogenase (oxaloacetate decarboxylating) YP_001943362.1 KEGG: cph:Cpha266_2432 hypothetical protein YP_001943363.1 KEGG: cph:Cpha266_2433 hypothetical protein YP_001943364.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: cph:Cpha266_1371 exodeoxyribonuclease I subunit D YP_001943365.1 PFAM: Ion transport 2 domain protein; KEGG: cph:Cpha266_1372 ion transport 2 domain protein YP_001943367.1 KEGG: hne:HNE_3258 lipoprotein YP_001943368.1 KEGG: cte:CT1238 hypothetical protein YP_001943369.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: cte:CT1524 phosphoketolase YP_001943370.1 TIGRFAM: acetate kinase; PFAM: acetate and butyrate kinase; KEGG: cte:CT1525 acetate kinase YP_001943371.1 KEGG: cph:Cpha266_1379 CopG family transcriptional regulator YP_001943372.1 KEGG: cph:Cpha266_1380 MazF family transcriptional regulator YP_001943373.1 TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: lbl:LBL_0797 membrane alanyl aminopeptidase YP_001943374.1 KEGG: ppd:Ppro_3838 hypothetical protein YP_001943375.1 KEGG: cph:Cpha266_1481 RNA-directed DNA polymerase (reverse transcriptase) YP_001943377.1 KEGG: aba:Acid345_4147 hypothetical protein YP_001943378.1 PFAM: helix-turn-helix domain protein; KEGG: cph:Cpha266_1375 XRE family transcriptional regulator YP_001943379.1 TIGRFAM: addiction module toxin, RelE/StbE family; PFAM: plasmid stabilization system; KEGG: cph:Cpha266_1376 addiction module toxin, RelE/StbE family YP_001943380.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: cph:Cpha266_1377 CopG family transcriptional regulator YP_001943381.1 KEGG: cph:Cpha266_1378 hypothetical protein YP_001943382.1 KEGG: gur:Gura_3957 hypothetical protein YP_001943383.1 KEGG: cph:Cpha266_1387 hypothetical protein YP_001943384.1 KEGG: cph:Cpha266_1388 hypothetical protein YP_001943385.1 PFAM: plasmid stabilization system; KEGG: cph:Cpha266_1389 plasmid stabilization system YP_001943386.1 KEGG: cph:Cpha266_1390 MazF family transcriptional regulator YP_001943387.1 KEGG: cph:Cpha266_1391 hypothetical protein YP_001943388.1 KEGG: cph:Cpha266_1379 CopG family transcriptional regulator YP_001943389.1 PFAM: PemK family protein; KEGG: cph:Cpha266_1380 MazF family transcriptional regulator YP_001943390.1 KEGG: cph:Cpha266_1392 protein of unknown function DUF1568 YP_001943391.1 PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cno:NT01CX_0321 helicase YP_001943392.1 KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001943393.1 PFAM: hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: sfr:Sfri_1847 hypothetical protein YP_001943394.1 KEGG: sse:Ssed_3658 nucleoside phosphorylase-like protein YP_001943395.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_2246 protein of unknown function DUF1568 YP_001943397.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: cph:Cpha266_1400 DNA helicase/exodeoxyribonuclease V, alpha subunit YP_001943398.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: cph:Cpha266_1401 DNA helicase/exodeoxyribonuclease V, beta subunit YP_001943399.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V RecC subunit; KEGG: cph:Cpha266_1402 DNA helicase/exodeoxyribonuclease V, gamma subunit YP_001943400.1 PFAM: membrane-flanked domain; KEGG: cph:Cpha266_1403 hypothetical protein YP_001943401.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1404 conserved hypothetical protein 341 YP_001943402.1 PFAM: proteinase inhibitor I4 serpin; KEGG: scl:sce2877 serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member YP_001943403.1 PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: mgm:Mmc1_1145 deoxyribodipyrimidine photo-lyase YP_001943404.1 KEGG: plt:Plut_1000 hypothetical protein YP_001943405.1 KEGG: cph:Cpha266_1274 hypothetical protein YP_001943406.1 PFAM: Protein of unknown function DUF1790; KEGG: pvi:Cvib_0087 hypothetical protein YP_001943407.1 TIGRFAM: addiction module antidote protein, HigA family; PFAM: helix-turn-helix domain protein; KEGG: cph:Cpha266_1407 plasmid maintenance system antidote protein, XRE family YP_001943408.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pvi:Cvib_0131 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001943409.1 PFAM: protein of unknown function DUF195; KEGG: cph:Cpha266_1053 protein of unknown function DUF195 YP_001943410.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001943411.1 PFAM: protein of unknown function DUF255; KEGG: cph:Cpha266_1460 protein of unknown function DUF255 YP_001943412.1 KEGG: cph:Cpha266_1461 hypothetical protein YP_001943413.1 KEGG: plt:Plut_0810 hypothetical protein YP_001943414.1 PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: cph:Cpha266_1064 carbamoyl-phosphate synthase L chain, ATP-binding YP_001943415.1 PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; KEGG: cph:Cpha266_1063 biotin/lipoyl attachment domain-containing protein YP_001943416.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001943417.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: reh:H16_A2324 dihydrolipoamide S-succinyltransferase (E2) YP_001943418.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rso:RSc1271 dihydrolipoamide dehydrogenase YP_001943419.1 PFAM: nuclease (SNase domain protein); KEGG: dol:Dole_2932 nuclease (SNase domain protein) YP_001943421.1 KEGG: hch:HCH_04190 hypothetical protein YP_001943422.1 KEGG: cph:Cpha266_1464 activator of HSP90 ATPase 1 family protein YP_001943423.1 PFAM: protein of unknown function DUF159; KEGG: cph:Cpha266_1054 protein of unknown function DUF159 YP_001943424.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: cph:Cpha266_1512 DegT/DnrJ/EryC1/StrS aminotransferase YP_001943425.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: cph:Cpha266_1513 iron-containing alcohol dehydrogenase YP_001943426.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: cte:CT1153 acylneuraminate cytidylyltransferase YP_001943427.1 KEGG: cte:CT1154 hypothetical protein YP_001943428.1 KEGG: cph:Cpha266_0798 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001943429.1 KEGG: cph:Cpha266_1516 hypothetical protein YP_001943430.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_1519 AMP-dependent synthetase and ligase YP_001943431.1 KEGG: cph:Cpha266_0655 hypothetical protein YP_001943432.1 PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: cph:Cpha266_1520 HhH-GPD family protein YP_001943433.1 PFAM: beta-lactamase domain protein; KEGG: plt:Plut_0970 metal-dependent hydrolase YP_001943434.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001943435.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001943436.1 TIGRFAM: 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; KEGG: cph:Cpha266_1523 16S rRNA processing protein RimM YP_001943437.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001943438.1 KEGG: cph:Cpha266_1525 signal recognition particle subunit FFH/SRP54 (SRP54); TIGRFAM: signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; Signal peptide binding (SRP54) M- domain protein; GTP-binding signal recognition particle SRP54 helical bundle; SMART: AAA ATPase YP_001943439.1 TIGRFAM: rfaE bifunctional protein; PFAM: PfkB domain protein; KEGG: cph:Cpha266_1526 RfaE bifunctional protein YP_001943440.1 KEGG: cph:Cpha266_1527 hypothetical protein YP_001943441.1 PFAM: cyclase/dehydrase; KEGG: cph:Cpha266_1528 cyclase/dehydrase YP_001943442.1 KEGG: cph:Cpha266_1529 C-terminal processing peptidase-3. Serine peptidase. MEROPS family S41A; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001943443.1 PFAM: Endoribonuclease L-PSP; KEGG: cph:Cpha266_1530 endoribonuclease L-PSP YP_001943444.1 PFAM: thiamine monophosphate synthase; KEGG: cph:Cpha266_1531 thiamine monophosphate synthase YP_001943445.1 KEGG: cph:Cpha266_1532 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase YP_001943446.1 TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: cph:Cpha266_1533 phosphomethylpyrimidine kinase YP_001943447.1 KEGG: pvi:Cvib_0945 UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase YP_001943448.1 KEGG: cph:Cpha266_1535 hypothetical protein YP_001943449.1 KEGG: cph:Cpha266_1536 hypothetical protein YP_001943450.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001943451.1 PFAM: phosphoesterase RecJ domain protein; KEGG: cph:Cpha266_1538 phosphoesterase, RecJ domain protein YP_001943452.1 KEGG: pvi:Cvib_0949 transcriptional regulator YP_001943453.1 TIGRFAM: radical SAM enzyme, Cfr family; PFAM: Radical SAM domain protein; KEGG: cph:Cpha266_1539 radical SAM enzyme, Cfr family YP_001943454.1 KEGG: cph:Cpha266_1540 hypothetical protein YP_001943455.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001943456.1 KEGG: cph:Cpha266_1542 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction protein res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases YP_001943457.1 PFAM: DoxX family protein; KEGG: cph:Cpha266_1543 DoxX family protein YP_001943458.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: cph:Cpha266_1507 efflux transporter, RND family, MFP subunit YP_001943459.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1508 protein of unknown function DUF214 YP_001943460.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_1509 ABC transporter YP_001943461.1 KEGG: cph:Cpha266_1634 conserved hypothetical protein-signal peptide prediction YP_001943462.1 PFAM: LmbE family protein; KEGG: sru:SRU_0866 GlcNAc-PI de-N-acetylase family YP_001943463.1 SMART: nuclear protein SET; KEGG: cph:Cpha266_1635 nuclear protein SET YP_001943464.1 KEGG: cch:Cag_1113 hypothetical protein YP_001943465.1 PFAM: iron-containing alcohol dehydrogenase; 3-dehydroquinate synthase; KEGG: cph:Cpha266_1004 iron-containing alcohol dehydrogenase YP_001943466.1 PFAM: protein of unknown function DUF134; KEGG: cph:Cpha266_1003 protein of unknown function DUF134 YP_001943467.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: cph:Cpha266_1002 C4-dicarboxylate transporter/malic acid transport protein YP_001943468.1 PFAM: OsmC family protein; KEGG: cph:Cpha266_1001 OsmC family protein YP_001943469.1 PFAM: HI0933 family protein; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1561 HI0933 family protein YP_001943470.1 TIGRFAM: RND efflux system, outer membrane lipoprotein, NodT family; PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_1562 RND efflux system, outer membrane lipoprotein, NodT family YP_001943471.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: cph:Cpha266_1563 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001943472.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; KEGG: cph:Cpha266_1564 efflux transporter, RND family, MFP subunit YP_001943473.1 PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: plt:Plut_0805 AraC family transcriptional regulator YP_001943474.1 KEGG: ppd:Ppro_1338 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding YP_001943475.1 PFAM: Protein of unknown function DUF1847; KEGG: cph:Cpha266_1986 hypothetical protein YP_001943477.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: cph:Cpha266_1567 NADH:flavin oxidoreductase/NADH oxidase YP_001943478.1 PFAM: Secreted repeat of unknown function; KEGG: plt:Plut_0063 hypothetical protein YP_001943479.1 PFAM: UbiA prenyltransferase; KEGG: cph:Cpha266_1569 UbiA prenyltransferase YP_001943480.1 KEGG: cph:Cpha266_1572 hypothetical protein YP_001943481.1 PFAM: fatty acid hydroxylase; KEGG: cph:Cpha266_1574 sterol desaturase YP_001943482.1 SMART: Rhodanese domain protein; KEGG: cph:Cpha266_1575 rhodanese domain protein YP_001943483.1 KEGG: cph:Cpha266_1576 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease YP_001943484.1 KEGG: bfs:BF2166 hypothetical protein YP_001943485.1 metalloprotease YP_001943486.1 KEGG: sma:SAV3183 hypothetical protein YP_001943489.1 KEGG: cph:Cpha266_1913 hypothetical protein YP_001943490.1 KEGG: cte:CT0924 hypothetical protein YP_001943491.1 PFAM: methyltransferase; KEGG: cph:Cpha266_1584 methyltransferase YP_001943492.1 KEGG: aeh:Mlg_2346 ATPase (AAA+ superfamily)-like protein YP_001943493.1 KEGG: pgi:PG1070 L-lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: Radical SAM domain protein YP_001943494.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001943495.1 PFAM: twitching mobility protein PilT; KEGG: dol:Dole_3167 twitching mobility protein PilT YP_001943496.1 TIGRFAM: AbrB family transcriptional regulator; PFAM: SpoVT/AbrB domain protein; KEGG: cph:Cpha266_2120 AbrB family transcriptional regulator YP_001943497.1 KEGG: bja:bll8207 hypothetical protein YP_001943498.1 KEGG: aav:Aave_3356 hypothetical protein YP_001943499.1 PFAM: SMC domain protein; KEGG: mar:MAE_39710 ATPase YP_001943500.1 KEGG: cph:Cpha266_1395 hypothetical protein YP_001943501.1 KEGG: cph:Cpha266_1396 hypothetical protein YP_001943502.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: sfu:Sfum_2856 DNA methylase N-4/N-6 domain protein YP_001943503.1 KEGG: cph:Cpha266_0634 transcriptional regulator YP_001943504.1 PFAM: type III restriction protein res subunit; KEGG: dau:Daud_0199 type III restriction enzyme, res subunit YP_001943505.1 PFAM: protein of unknown function DUF86; KEGG: cph:Cpha266_0768 protein of unknown function DUF86 YP_001943506.1 PFAM: DNA polymerase beta domain protein region; KEGG: cph:Cpha266_0766 DNA polymerase, beta domain protein region YP_001943507.1 KEGG: cph:Cpha266_1985 hypothetical protein YP_001943508.1 PFAM: pentapeptide repeat protein; KEGG: cph:Cpha266_1984 pentapeptide repeat protein YP_001943509.1 PFAM: HipA domain protein; KEGG: aba:Acid345_2426 HipA-like protein YP_001943511.1 PFAM: leucine-rich repeat protein; Miro domain protein; KEGG: ter:Tery_3798 small GTP-binding protein YP_001943512.1 SMART: TIR protein; KEGG: amr:AM1_H0064 hypothetical protein YP_001943513.1 KEGG: cch:Cag_1797 hypothetical protein YP_001943514.1 PFAM: helix-turn-helix domain protein; KEGG: cch:Cag_1798 XRE family transcriptional regulator YP_001943515.1 KEGG: cch:Cag_1799 hypothetical protein YP_001943516.1 KEGG: cph:Cpha266_2139 transposase and inactivated derivatives YP_001943517.1 PFAM: DNA repair protein RadC; KEGG: cph:Cpha266_1619 DNA repair protein RadC YP_001943518.1 KEGG: cch:Cag_1820 hypothetical protein YP_001943519.1 KEGG: cph:Cpha266_1622 hypothetical protein YP_001943520.1 KEGG: cph:Cpha266_1628 inosine-5'-monophosphate dehydrogenase; TIGRFAM: inosine-5'-monophosphate dehydrogenase; PFAM: CBS domain containing protein; IMP dehydrogenase/GMP reductase YP_001943521.1 KEGG: cte:CT1294 hypothetical protein YP_001943522.1 PFAM: protein of unknown function DUF1615; KEGG: cte:CT1294 hypothetical protein YP_001943523.1 KEGG: cph:Cpha266_1630 protoporphyrin IX magnesium-chelatase; TIGRFAM: magnesium chelatase ATPase subunit D; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase YP_001943524.1 KEGG: cph:Cpha266_1631 protoporphyrin IX magnesium-chelatase; TIGRFAM: magnesium chelatase ATPase subunit I; SMART: AAA ATPase YP_001943525.1 TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase; KEGG: cph:Cpha266_1632 dihydrolipoamide dehydrogenase YP_001943526.1 KEGG: plt:Plut_0783 pseudouridine synthase, RluD; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001943527.1 KEGG: cte:CT1305 hypothetical protein YP_001943528.1 KEGG: cph:Cpha266_1359 hypothetical protein YP_001943529.1 PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: cph:Cpha266_1010 Oligopeptidase B. Serine peptidase. MEROPS family S09A YP_001943530.1 PFAM: DNA alkylation repair enzyme; KEGG: cte:CT1302 hypothetical protein YP_001943531.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_1008 Fis family transcriptional regulator YP_001943532.1 KEGG: pvi:Cvib_1065 hypothetical protein YP_001943533.1 PFAM: Abortive infection protein; KEGG: plt:Plut_0757 abortive infection protein-like YP_001943534.1 KEGG: cph:Cpha266_0714 hypothetical protein YP_001943535.1 KEGG: cph:Cpha266_1154 hypothetical protein YP_001943536.1 PFAM: Di-haem cytochrome c peroxidase; KEGG: cph:Cpha266_1353 cytochrome-c peroxidase YP_001943537.1 KEGG: cph:Cpha266_2350 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001943538.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_1636 short-chain dehydrogenase/reductase SDR YP_001943539.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_1637 alpha/beta hydrolase fold YP_001943540.1 PFAM: thymidylate kinase; KEGG: cph:Cpha266_1638 thymidylate kinase YP_001943541.1 KEGG: pvi:Cvib_1046 hypothetical protein YP_001943542.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; Haloacid dehalogenase domain protein hydrolase; KEGG: cph:Cpha266_1640 beta-phosphoglucomutase family hydrolase YP_001943543.1 TIGRFAM: S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; KEGG: plt:Plut_1313 S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_001943544.1 TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; KEGG: cph:Cpha266_1642 4-diphosphocytidyl-2C-methyl-D-erythritol synthase YP_001943545.1 PFAM: thioesterase superfamily protein; KEGG: cch:Cag_0930 phenylacetic acid degradation-related protein YP_001943546.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cph:Cpha266_1644 radical SAM domain protein YP_001943547.1 KEGG: plt:Plut_0061 hypothetical protein YP_001943548.1 PFAM: Curli production assembly/transport component CsgG; KEGG: cph:Cpha266_1717 curli production assembly/transport component CsgG YP_001943549.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001943550.1 PFAM: ribonuclease BN; KEGG: cph:Cpha266_1653 ribonuclease BN YP_001943551.1 PFAM: major facilitator superfamily MFS_1; KEGG: pvi:Cvib_0729 major facilitator superfamily MFS_1 YP_001943552.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001943553.1 TIGRFAM: phosphoribosylformylglycinamidine synthase, purS; PFAM: phosphoribosylformylglycinamidine synthetase PurS; KEGG: pvi:Cvib_0727 phosphoribosylformylglycinamidine synthase, PurS YP_001943554.1 TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cph:Cpha266_1657 CDP-diacylglycerol--serine O-phosphatidyltransferase YP_001943555.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001943556.1 PFAM: biotin/lipoate A/B protein ligase; KEGG: plt:Plut_1329 lipoate-protein ligase A-like YP_001943557.1 KEGG: cph:Cpha266_1660 hypothetical protein YP_001943558.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001943559.1 KEGG: cte:CT1346 hypothetical protein YP_001943560.1 PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_1665 outer membrane efflux protein YP_001943561.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: cph:Cpha266_1666 efflux transporter, RND family, MFP subunit YP_001943562.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: plt:Plut_1335 ATPase YP_001943563.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1668 protein of unknown function DUF214 YP_001943564.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1669 protein of unknown function DUF214 YP_001943565.1 KEGG: cph:Cpha266_1670 hypothetical protein YP_001943566.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: plt:Plut_1338 OmpA family protein YP_001943567.1 KEGG: cph:Cpha266_1672 hypothetical protein YP_001943568.1 TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; PFAM: transferase hexapeptide repeat containing protein; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; KEGG: cph:Cpha266_1673 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_001943570.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001943571.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001943572.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cph:Cpha266_1676 binding-protein-dependent transport systems inner membrane component YP_001943573.1 PFAM: NUDIX hydrolase; KEGG: cph:Cpha266_1677 NUDIX hydrolase YP_001943574.1 KEGG: plt:Plut_1345 hypothetical protein YP_001943575.1 KEGG: cph:Cpha266_0748 hypothetical protein YP_001943577.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2240 IstB domain protein ATP-binding protein YP_001943579.1 PFAM: ComEC/Rec2-related protein; KEGG: cph:Cpha266_1722 ComEC/Rec2-related protein YP_001943580.1 KEGG: cph:Cpha266_1723 5,10-methylenetetrahydrofolate reductase; TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase YP_001943581.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: cph:Cpha266_1724 diaminopimelate decarboxylase YP_001943582.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001943583.1 PFAM: protein of unknown function DUF164; KEGG: plt:Plut_1350 hypothetical protein YP_001943584.1 KEGG: cte:CT1379 hypothetical protein YP_001943585.1 KEGG: cph:Cpha266_1728 hypothetical protein YP_001943586.1 PFAM: aminotransferase class I and II; KEGG: cch:Cag_0798 aspartate aminotransferase YP_001943587.1 KEGG: cph:Cpha266_1731 hypothetical protein YP_001943588.1 PFAM: protein of unknown function DUF456; KEGG: plt:Plut_0433 hypothetical protein YP_001943589.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001943590.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: cps:CPS_3973 biopolymer transport ExbD protein YP_001943591.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: met:M446_0507 TonB family protein YP_001943592.1 PFAM: iron dependent repressor; FeoA family protein; KEGG: cte:CT1737 iron-dependent repressor YP_001943593.1 KEGG: cph:Cpha266_0315 hypothetical protein YP_001943594.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: tex:Teth514_0307 cobalamin (vitamin B12) biosynthesis CbiX protein YP_001943595.1 KEGG: bth:BT_3628 hypothetical protein YP_001943596.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiX protein; KEGG: hmo:HM1_2393 sirohydrochlorin cobaltochelatase YP_001943597.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001943598.1 KEGG: dde:Dde_0446 hypothetical protein YP_001943599.1 KEGG: dde:Dde_0446 hypothetical protein YP_001943600.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: dde:Dde_0445 ATPase YP_001943601.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001943602.1 KEGG: cch:Cag_0916 C-type cytochrome YP_001943603.1 KEGG: bay:RBAM_007330 YezD YP_001943604.1 PFAM: ferredoxin; KEGG: cph:Cpha266_1733 ferredoxin YP_001943605.1 KEGG: cph:Cpha266_1734 hypothetical protein YP_001943606.1 KEGG: cph:Cpha266_1735 hypothetical protein YP_001943607.1 PFAM: protein of unknown function UPF0054; KEGG: cph:Cpha266_1736 protein of unknown function UPF0054 YP_001943608.1 TIGRFAM: GTP-binding proten HflX; PFAM: GTP-binding protein HSR1-related; KEGG: cph:Cpha266_1737 GTP-binding protein, HSR1-related YP_001943609.1 PFAM: Squalene/phytoene synthase; KEGG: cph:Cpha266_1738 squalene/phytoene synthase YP_001943610.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001943611.1 PFAM: AAA-4 family protein; KEGG: cph:Cpha266_1740 transcriptional regulator YP_001943612.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pvi:Cvib_1219 NAD-dependent epimerase/dehydratase YP_001943613.1 PFAM: NGN domain protein; SMART: KOW domain protein; KEGG: cch:Cag_0149 NusG antitermination factor YP_001943614.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_0166 tetratricopeptide TPR_2 repeat protein YP_001943615.1 KEGG: cph:Cpha266_1759 queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylase, various specificities; queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase YP_001943616.1 KEGG: cte:CT1398 hypothetical protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme YliG; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB YP_001943617.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: ava:Ava_3014 DNA methylase N-4/N-6 YP_001943619.1 PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2240 IstB domain protein ATP-binding protein YP_001943620.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_2241 integrase, catalytic region YP_001943621.1 KEGG: gme:Gmet_1012 hemerythrin HHE cation binding region YP_001943622.1 KEGG: cph:Cpha266_1247 PAS/PAC sensor protein YP_001943623.1 KEGG: cph:Cpha266_1788 PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; SMART: PAS domain containing protein YP_001943624.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1465 hypothetical protein YP_001943625.1 PFAM: Patatin; KEGG: sus:Acid_5056 patatin YP_001943626.1 PFAM: amino acid permease-associated region; KEGG: cte:CT0923 amino acid permease YP_001943627.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: cph:Cpha266_0173 ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_001943628.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; FAD linked oxidase domain protein; KEGG: cph:Cpha266_1511 FAD linked oxidase domain protein YP_001943629.1 KEGG: cph:Cpha266_1051 hypothetical protein YP_001943630.1 PFAM: protein of unknown function nitrogen fixation; KEGG: pth:PTH_2367 hypothetical protein YP_001943631.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: cte:CT0920 7-alpha-hydroxysteroid dehydrogenase YP_001943632.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1049 glycosyl transferase, family 2 YP_001943633.1 PFAM: pentapeptide repeat protein; KEGG: cph:Cpha266_1048 pentapeptide repeat protein YP_001943634.1 KEGG: cph:Cpha266_1047 hypothetical protein YP_001943635.1 KEGG: cph:Cpha266_1046 hypothetical protein YP_001943636.1 PFAM: acriflavin resistance protein; KEGG: cph:Cpha266_1045 acriflavin resistance protein YP_001943637.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: cph:Cpha266_1044 efflux transporter, RND family, MFP subunit YP_001943638.1 KEGG: cph:Cpha266_1043 phosphate uptake regulator, PhoU YP_001943639.1 TIGRFAM: phosphate transport system regulatory protein PhoU; PFAM: PhoU family protein; KEGG: pvi:Cvib_0993 phosphate uptake regulator, PhoU YP_001943640.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001943641.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: cph:Cpha266_1040 phosphate ABC transporter, inner membrane subunit PstA YP_001943642.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstC; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: plt:Plut_1244 phosphate ABC transporter, permease protein PstC YP_001943643.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: cph:Cpha266_1038 phosphate binding protein YP_001943644.1 TIGRFAM: phosphate binding protein; PFAM: extracellular solute-binding protein family 1; KEGG: cph:Cpha266_1037 phosphate binding protein YP_001943645.1 KEGG: cph:Cpha266_1036 hypothetical protein YP_001943646.1 KEGG: pvi:Cvib_1000 hypothetical protein YP_001943647.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cph:Cpha266_1034 hypothetical protein YP_001943648.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: pvi:Cvib_1002 phospholipid/glycerol acyltransferase YP_001943649.1 KEGG: amt:Amet_0696 anion transporter YP_001943650.1 PFAM: permease YjgP/YjgQ family protein; KEGG: cph:Cpha266_0940 permease YjgP/YjgQ family protein YP_001943652.1 TIGRFAM: preprotein translocase, SecG subunit; KEGG: cph:Cpha266_0931 preprotein translocase subunit SecG YP_001943653.1 KEGG: cph:Cpha266_0930 hypothetical protein YP_001943654.1 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis YP_001943655.1 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP YP_001943656.1 KEGG: cph:Cpha266_0927 hypothetical protein YP_001943657.1 KEGG: cph:Cpha266_0926 hypothetical protein YP_001943658.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001943659.1 PFAM: acriflavin resistance protein; KEGG: plt:Plut_0709 RND family efflux transporter YP_001943660.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: plt:Plut_0708 secretion protein HlyD YP_001943661.1 PFAM: NUDIX hydrolase; KEGG: cph:Cpha266_0924 NUDIX hydrolase YP_001943662.1 PFAM: Nucleotidyl transferase; KEGG: pvi:Cvib_1120 nucleotidyl transferase YP_001943663.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001943664.1 catalyzes the formation of L-homocysteine from S-adenosyl-L-homocysteine YP_001943665.1 PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: cph:Cpha266_0920 phosphoribosylanthranilate isomerase YP_001943666.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_0919 alpha/beta hydrolase fold YP_001943667.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: cph:Cpha266_0917 sodium/hydrogen exchanger YP_001943668.1 PFAM: Rubrerythrin; KEGG: cph:Cpha266_0916 rubrerythrin YP_001943669.1 KEGG: cph:Cpha266_0915 hypothetical protein YP_001943670.1 TIGRFAM: sulfate transporter; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: plt:Plut_0667 sulphate anion transporter YP_001943671.1 KEGG: cph:Cpha266_0912 hypothetical protein YP_001943672.1 TIGRFAM: nitrogenase-associated protein; PFAM: arsenate reductase and related; KEGG: cph:Cpha266_0911 nitrogenase-associated protein YP_001943673.1 KEGG: cph:Cpha266_0910 hypothetical protein YP_001943674.1 PFAM: TspO/MBR family protein; KEGG: plt:Plut_0665 CrtK protein YP_001943675.1 KEGG: cte:CT0707 hypothetical protein YP_001943676.1 KEGG: plt:Plut_0663 alanine dehydrogenase and pyridine nucleotide transhydrogenase; TIGRFAM: alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein YP_001943677.1 KEGG: cph:Cpha266_0905 hypothetical protein YP_001943678.1 KEGG: cph:Cpha266_1839 hypothetical protein YP_001943679.1 PFAM: protein of unknown function DUF45; KEGG: cph:Cpha266_0904 protein of unknown function DUF45 YP_001943680.1 PFAM: secretion protein HlyD family protein; KEGG: cph:Cpha266_1842 secretion protein HlyD family protein YP_001943681.1 KEGG: cph:Cpha266_1843 cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters; TIGRFAM: type I secretion system ATPase; PFAM: cyclic nucleotide-binding; ABC transporter transmembrane region; ABC transporter; peptidase C39 bacteriocin processing; SMART: AAA ATPase YP_001943682.1 KEGG: cph:Cpha266_1844 hypothetical protein YP_001943683.1 PFAM: Hemolysin-type calcium-binding region; von Willebrand factor type A; KEGG: lpf:lpl0681 structural toxin protein RtxA YP_001943684.1 PFAM: Hemolysin-type calcium-binding region; KEGG: ana:alr7304 similar to hlyA YP_001943685.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_1845 type I secretion outer membrane protein, TolC family YP_001943686.1 TIGRFAM: outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor type A; KEGG: lpf:lpl0681 structural toxin protein RtxA YP_001943687.1 PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; KEGG: cph:Cpha266_1847 6-pyruvoyl tetrahydropterin synthase and hypothetical protein YP_001943688.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cph:Cpha266_1848 radical SAM domain protein YP_001943689.1 PFAM: PUCC protein; KEGG: cph:Cpha266_1849 PucC protein YP_001943690.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001943691.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001943692.1 KEGG: cph:Cpha266_1853 hypothetical protein YP_001943693.1 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus YP_001943694.1 KEGG: cph:Cpha266_1855 protease Do; TIGRFAM: protease Do; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein YP_001943695.1 KEGG: pvi:Cvib_1279 anthranilate synthase, component I; TIGRFAM: anthranilate synthase component I; PFAM: Anthranilate synthase component I domain protein; Chorismate binding-like YP_001943696.1 KEGG: cph:Cpha266_1857 hypothetical protein YP_001943697.1 KEGG: cph:Cpha266_1858 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24 and S26 domain protein YP_001943698.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001943699.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: cph:Cpha266_1860 methionyl-tRNA formyltransferase YP_001943700.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001943701.1 PFAM: ferric-uptake regulator; KEGG: cph:Cpha266_0314 ferric uptake regulator, Fur family YP_001943702.1 PFAM: sodium/hydrogen exchanger; KEGG: cph:Cpha266_1862 sodium/hydrogen exchanger YP_001943704.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001943705.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001943706.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_1866 ABC transporter YP_001943707.1 PFAM: major facilitator superfamily MFS_1; KEGG: cph:Cpha266_1867 major facilitator superfamily MFS_1 YP_001943708.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: cph:Cpha266_1868 DegT/DnrJ/EryC1/StrS aminotransferase YP_001943709.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_1869 UDP-N-acetylmuramate--L-alanine ligase YP_001943710.1 KEGG: cph:Cpha266_1870 glyceraldehyde-3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001943711.1 PFAM: Proto-chlorophyllide reductase 57 kD subunit; KEGG: cph:Cpha266_1871 Proto-chlorophyllide reductase 57 kD subunit YP_001943712.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001943713.1 PFAM: GrpE protein; KEGG: cph:Cpha266_1873 GrpE protein YP_001943714.1 TIGRFAM: heat-inducible transcription repressor HrcA; PFAM: Negative regulator of class I heat shock protein; KEGG: cph:Cpha266_1874 heat-inducible transcription repressor HrcA YP_001943715.1 TIGRFAM: modification methylase, HemK family; protein-(glutamine-N5) methyltransferase, release factor-specific; PFAM: methyltransferase small; KEGG: cph:Cpha266_1875 modification methylase, HemK family YP_001943716.1 KEGG: cph:Cpha266_1876 hypothetical protein YP_001943717.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001943718.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001943719.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease YP_001943720.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: plt:Plut_1495 carbon-nitrogen hydrolase family protein YP_001943721.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001943722.1 PFAM: Sporulation domain protein; KEGG: cte:CT1496 hypothetical protein YP_001943723.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_1886 sigma54 specific Fis family transcriptional regulator YP_001943724.1 TIGRFAM: apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cph:Cpha266_1887 apolipoprotein N-acyltransferase YP_001943725.1 PFAM: bacteriochlorophyll A protein; KEGG: cph:Cpha266_1888 bacteriochlorophyll A protein YP_001943726.1 PFAM: regulatory protein MerR; KEGG: cch:Cag_1328 MerR family transcriptional regulator YP_001943727.1 PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; KEGG: plt:Plut_1502 ATPase YP_001943728.1 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis YP_001943729.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cph:Cpha266_1895 radical SAM domain protein YP_001943730.1 This protein performs the mismatch recognition step during the DNA repair process YP_001943731.1 KEGG: cph:Cpha266_1897 hypothetical protein YP_001943732.1 PFAM: ribosomal protein L21; KEGG: pvi:Cvib_1329 50S ribosomal protein L21 YP_001943733.1 involved in the peptidyltransferase reaction during translation YP_001943734.1 Catalyzes the reversible oxidation of malate to oxaloacetate YP_001943735.1 PFAM: Porphyromonas-type peptidyl-arginine deiminase; KEGG: cte:CT1508 hypothetical protein YP_001943736.1 PFAM: peptidase M48 Ste24p; KEGG: cph:Cpha266_1902 STE24 endopeptidase YP_001943737.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: cph:Cpha266_1903 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase YP_001943738.1 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate YP_001943739.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cph:Cpha266_1905 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001943740.1 KEGG: cph:Cpha266_1906 hypothetical protein YP_001943741.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001943742.1 PFAM: protein of unknown function zinc metallopeptidase KEGG: esi:Exig_0173 protein of unknown function zinc metallopeptidase YP_001943743.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: cph:Cpha266_1910 NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30 YP_001943744.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_1911 uncharacterized protein UPF0114 YP_001943745.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2 transporter protein CorA family protein; KEGG: plt:Plut_1521 magnesium and cobalt transport protein CorA YP_001943746.1 KEGG: cch:Cag_1724 hypothetical protein YP_001943747.1 PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: cph:Cpha266_0673 alpha amylase, catalytic region YP_001943748.1 PFAM: protein of unknown function UPF0047; KEGG: pvi:Cvib_0499 protein of unknown function UPF0047 YP_001943749.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001943750.1 PFAM: phosphatidylglycerophosphatase A; KEGG: cph:Cpha266_0670 phosphatidylglycerophosphatase YP_001943751.1 TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; KEGG: cph:Cpha266_0669 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_001943752.1 PFAM: DNA mismatch repair protein MutS domain protein; Smr protein/MutS2; SMART: MutS III domain protein; KEGG: cph:Cpha266_0668 Smr protein/MutS2 YP_001943753.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001943754.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001943755.1 phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001943756.1 PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; KEGG: cph:Cpha266_0664 PHP C-terminal domain protein YP_001943757.1 PFAM: protein of unknown function DUF140; KEGG: pvi:Cvib_0490 protein of unknown function DUF140 YP_001943758.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: plt:Plut_0441 ATPase YP_001943759.1 PFAM: Mammalian cell entry related domain protein; KEGG: cph:Cpha266_0661 mammalian cell entry related domain protein YP_001943760.1 PFAM: beta-lactamase; KEGG: cph:Cpha266_0660 beta-lactamase YP_001943761.1 PFAM: response regulator receiver; sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: mgm:Mmc1_3600 two component, sigma54 specific, transcriptional regulator, fis family YP_001943762.1 PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: mgm:Mmc1_3601 periplasmic sensor signal transduction histidine kinase YP_001943763.1 KEGG: pla:Plav_1014 potassium-transporting ATPase, A subunit; TIGRFAM: potassium-transporting ATPase, A subunit; PFAM: K transporting ATPase A subunit YP_001943764.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; K+-transporting ATPase, B subunit; PFAM: Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: dge:Dgeo_2849 potassium-translocating P-type ATPase, B subunit YP_001943765.1 PFAM: K transporting ATPase KdpC subunit; KEGG: pla:Plav_1015 potassium-transporting ATPase YP_001943766.1 PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; Osmosensitive K channel His kinase sensor; KEGG: sfu:Sfum_2617 osmosensitive K+ channel His kinase sensor YP_001943767.1 PFAM: amine oxidase; Rieske [2Fe-2S] domain protein; FAD dependent oxidoreductase; KEGG: cph:Cpha266_0659 Rieske (2Fe-2S) domain protein YP_001943768.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: cph:Cpha266_0658 domain of unknown function DUF1730 YP_001943769.1 involved in de novo purine biosynthesis YP_001943770.1 PFAM: N-acetyltransferase; KEGG: cph:Cpha266_1973 N-acetyltransferase YP_001943771.1 KEGG: cph:Cpha266_1695 hypothetical protein YP_001943772.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: cph:Cpha266_1144 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001943773.1 KEGG: cph:Cpha266_1559 hypothetical protein YP_001943774.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: rci:RRC139 lysine exporter (LysE family) YP_001943775.1 KEGG: cph:Cpha266_1224 hypothetical protein YP_001943776.1 PFAM: PDZ/DHR/GLGF domain protein; KEGG: esi:Exig_2418 carboxyl-terminal protease YP_001943777.1 KEGG: net:Neut_2361 transposase, mutator type YP_001943778.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001943779.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1954 integrase, catalytic region YP_001943780.1 KEGG: spl:Spea_0729 hypothetical protein YP_001943781.1 KEGG: bth:BT_2774 adenylate cyclase YP_001943782.1 KEGG: plt:Plut_1921 ATPase (AAA+ superfamily)-like YP_001943783.1 TIGRFAM: phosphoribosylglycinamide formyltransferase; PFAM: formyl transferase domain protein; KEGG: cch:Cag_0504 phosphoribosylglycinamide formyltransferase YP_001943784.1 PFAM: Radical SAM domain protein; KEGG: cph:Cpha266_1979 radical SAM domain protein YP_001943785.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1980 glycosyl transferase, family 2 YP_001943786.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_001943787.1 PFAM: protein of unknown function DUF214; KEGG: cph:Cpha266_1982 cell division protein FtsX YP_001943788.1 KEGG: cph:Cpha266_1983 hypothetical protein YP_001943789.1 TIGRFAM: amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; KEGG: cph:Cpha266_1989 amidophosphoribosyltransferase YP_001943790.1 KEGG: plt:Plut_0424 transcriptional regulators, TraR/DksA family YP_001943791.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin) YP_001943792.1 KEGG: plt:Plut_0422 hypothetical protein YP_001943793.1 KEGG: plt:Plut_0421 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein YP_001943794.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_1993 UDP-galactose 4-epimerase YP_001943795.1 KEGG: cph:Cpha266_1994 hypothetical protein YP_001943796.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_1995 dTDP-glucose 4,6-dehydratase YP_001943797.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: cph:Cpha266_1996 dTDP-4-dehydrorhamnose reductase YP_001943798.1 KEGG: cch:Cag_0514 dTDP-4-dehydrorhamnose 3,5-epimerase related; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related YP_001943799.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: cph:Cpha266_1998 glucose-1-phosphate thymidylyltransferase YP_001943800.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: cph:Cpha266_0725 hydrogenase expression/formation protein HypE YP_001943801.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: cph:Cpha266_0724 hydrogenase expression/formation protein HypD YP_001943802.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: cte:CT1795 hydrogenase assembly chaperone HypC/HupF YP_001943803.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC domain; zinc finger HypF domain protein; KEGG: cph:Cpha266_0722 (NiFe) hydrogenase maturation protein HypF YP_001943804.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K; KEGG: cte:CT1798 hydrogenase accessory protein HypB YP_001943805.1 TIGRFAM: hydrogenase nickel insertion protein HypA; PFAM: hydrogenase expression/synthesis HypA; KEGG: cph:Cpha266_0720 hydrogenase expression/synthesis, HypA YP_001943806.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_001943807.1 KEGG: cph:Cpha266_0718 hypothetical protein YP_001943808.1 PFAM: NUDIX hydrolase; KEGG: cph:Cpha266_0717 NUDIX hydrolase YP_001943809.1 PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; KEGG: cph:Cpha266_0188 coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein YP_001943810.1 KEGG: cph:Cpha266_0714 hypothetical protein YP_001943811.1 KEGG: plt:Plut_0487 hypothetical protein YP_001943812.1 PFAM: Na+/solute symporter; KEGG: cte:CT1806 sodium:solute symporter family protein YP_001943813.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001943814.1 PFAM: hypothetical protein; Tetratricopeptide TPR_3; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_0709 tetratricopeptide TPR_2 repeat protein YP_001943815.1 TIGRFAM: shikimate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding domain protein; KEGG: cph:Cpha266_0708 shikimate dehydrogenase YP_001943816.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001943817.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: cph:Cpha266_0706 hydrolase, TatD family YP_001943818.1 PFAM: hypothetical protein; KEGG: cph:Cpha266_0705 tetratricopeptide TPR_2 repeat protein YP_001943819.1 PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; KEGG: cph:Cpha266_0704 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001943820.1 PFAM: alanine racemase domain protein; KEGG: cph:Cpha266_0703 alanine racemase domain protein YP_001943821.1 PFAM: aminotransferase class I and II; KEGG: aba:Acid345_1458 aminotransferase, class I and II YP_001943822.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_001943823.1 KEGG: plt:Plut_0476 initiation factor 2B alpha/beta/delta; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: initiation factor 2B related YP_001943824.1 PFAM: cytochrome c oxidase subunit I; KEGG: cch:Cag_1356 cytochrome-cbb3 oxidase, subunit I YP_001943825.1 CcoO; FixO YP_001943827.1 PFAM: cytochrome c class I; KEGG: cch:Cag_1358 probable cb-type cytochrome c oxidase subunit III YP_001943828.1 KEGG: cch:Cag_1359 polyferredoxin-like YP_001943829.1 KEGG: cch:Cag_1367 hypothetical protein YP_001943830.1 KEGG: cch:Cag_1368 hypothetical protein YP_001943831.1 KEGG: cch:Cag_1369 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein YP_001943832.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: cch:Cag_1370 cytochrome oxidase maturation protein cbb3-type YP_001943833.1 KEGG: cch:Cag_1371 hypothetical protein YP_001943834.1 PFAM: cytochrome bd ubiquinol oxidase subunit I; KEGG: cph:Cpha266_0700 cytochrome bd ubiquinol oxidase, subunit I YP_001943835.1 KEGG: cph:Cpha266_0699 cytochrome d ubiquinol oxidase, subunit II; TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase subunit II YP_001943836.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001943837.1 PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; KEGG: cph:Cpha266_1762 cold-shock DNA-binding protein family YP_001943838.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_1763 short-chain dehydrogenase/reductase SDR YP_001943840.1 KEGG: cch:Cag_0694 hypothetical protein YP_001943841.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001943842.1 KEGG: cph:Cpha266_1766 homoserine O-acetyltransferase; TIGRFAM: homoserine O-acetyltransferase; PFAM: alpha/beta hydrolase fold YP_001943843.1 KEGG: plt:Plut_0592 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase YP_001943844.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: cph:Cpha266_1768 sun protein YP_001943845.1 TIGRFAM: tyrosine recombinase XerD; PFAM: integrase family protein; integrase; KEGG: cph:Cpha266_1769 tyrosine recombinase XerD YP_001943846.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_1770 hypothetical protein YP_001943847.1 KEGG: cph:Cpha266_1771 hypothetical protein YP_001943848.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: cph:Cpha266_1772 beta-lactamase domain protein YP_001943849.1 KEGG: cph:Cpha266_1834 multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001943850.1 KEGG: cph:Cpha266_1833 PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; Stage II sporulation E family protein; PAS fold domain protein; SMART: PAS domain containing protein; protein phosphatase 2C domain protein YP_001943851.1 PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: cph:Cpha266_1832 sigma54 specific Fis family transcriptional regulator YP_001943852.1 KEGG: cph:Cpha266_1831 N-acetylmannosaminyltransferase; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF YP_001943853.1 PFAM: sugar transferase; KEGG: cph:Cpha266_1830 undecaprenyl-phosphate galactose phosphotransferase YP_001943854.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cph:Cpha266_1829 anti-sigma-factor antagonist YP_001943855.1 KEGG: cph:Cpha266_1828 nucleoside-diphosphate-sugar pyrophosphorylase YP_001943856.1 TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cph:Cpha266_1827 anti-sigma-factor antagonist YP_001943857.1 KEGG: cph:Cpha266_1826 anti-sigma regulatory factor, serine/threonine protein kinase YP_001943858.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1825 glycosyl transferase, family 2 YP_001943859.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: cph:Cpha266_1824 serine O-acetyltransferase YP_001943860.1 PFAM: polysaccharide export protein; KEGG: cph:Cpha266_1823 polysaccharide export protein YP_001943861.1 PFAM: polysaccharide biosynthesis protein; KEGG: cph:Cpha266_1820 polysaccharide biosynthesis protein YP_001943862.1 KEGG: cph:Cpha266_1819 uncharacterized protein involved in exopolysaccharide biosynthesis-like YP_001943863.1 KEGG: plt:Plut_1371 serine acetyltransferase-like YP_001943864.1 PFAM: glycosyl transferase group 1; KEGG: plt:Plut_1372 glycosyltransferase-like YP_001943865.1 KEGG: cph:Cpha266_1816 hypothetical protein YP_001943866.1 KEGG: cph:Cpha266_1815 hypothetical protein YP_001943867.1 KEGG: cph:Cpha266_0890 hypothetical protein YP_001943868.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1813 glycosyl transferase, family 2 YP_001943869.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_1812 glycosyl transferase, group 1 YP_001943870.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_1811 glycosyl transferase, family 2 YP_001943871.1 KEGG: plt:Plut_1385 hypothetical protein YP_001943872.1 PFAM: helicase domain protein; DbpA RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases; KEGG: cph:Cpha266_1774 DEAD/DEAH box helicase domain protein YP_001943873.1 PFAM: hypothetical protein; Tetratricopeptide TPR_4; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_1566 tetratricopeptide TPR_2 repeat protein YP_001943874.1 PFAM: Integral membrane protein TerC; KEGG: cph:Cpha266_1776 integral membrane protein TerC YP_001943875.1 PFAM: K potassium transporter; KEGG: cph:Cpha266_1777 K+ potassium transporter YP_001943876.1 KEGG: ptr:743163 similar to ENSANGP00000001657 YP_001943877.1 KEGG: cph:Cpha266_0597 hypothetical protein YP_001943878.1 PFAM: Ferritin Dps family protein; KEGG: cph:Cpha266_0596 ferritin, Dps family protein YP_001943879.1 PFAM: metallophosphoesterase; KEGG: plt:Plut_1594 hypothetical protein YP_001943880.1 TIGRFAM: dihydroorotate dehydrogenase family protein; PFAM: dihydroorotate dehydrogenase; KEGG: cch:Cag_1783 dihydroorotate dehydrogenase 1 YP_001943881.1 PFAM: S23 ribosomal protein; KEGG: sun:SUN_0718 S23 ribosomal protein YP_001943882.1 KEGG: cph:Cpha266_0592 hypothetical protein YP_001943883.1 KEGG: cau:Caur_1775 forkhead-associated protein YP_001943884.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001943885.1 KEGG: cph:Cpha266_0587 DNA-directed DNA polymerase YP_001943886.1 PFAM: Hemolysin-type calcium-binding region; KEGG: amr:AM1_3186 hemolysin-type calcium-binding protein YP_001943887.1 PFAM: glycosyl transferase group 1; KEGG: pme:NATL1_21041 hypothetical protein YP_001943888.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_2318 glycosyl transferase, group 1 YP_001943889.1 PFAM: Hemolysin-type calcium-binding region; KEGG: psp:PSPPH_0815 calcium binding hemolysin protein YP_001943891.1 PFAM: metallophosphoesterase; KEGG: sus:Acid_7022 metallophosphoesterase YP_001943892.1 KEGG: mxa:MXAN_2068 translation initiation factor IF-2 YP_001943893.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: pvi:Cvib_0649 NAD-dependent epimerase/dehydratase YP_001943895.1 PFAM: HpcH/HpaI aldolase; KEGG: mbu:Mbur_1595 2-dehydro-3-deoxyglucarate aldolase YP_001943896.1 PFAM: cyclase family protein; KEGG: mbu:Mbur_1598 cyclase YP_001943897.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: mbu:Mbur_1594 acylneuraminate cytidylyltransferase YP_001943898.1 KEGG: cth:Cthe_0640 cellulosome enzyme, dockerin type I YP_001943899.1 PFAM: conserved hypothetical protein; KEGG: cac:CAC0836 beta-D-galactosidase YP_001943900.1 PFAM: 3-dehydroquinate synthase; KEGG: mag:amb0135 3-dehydroquinate synthetase YP_001943901.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ctc:CTC00130 3-ketoacyl-(acyl-carrier-protein) reductase YP_001943902.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: mag:amb0132 predicted dehydrogenase and related protein YP_001943903.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: nis:NIS_0664 D-3-phosphoglycerate dehydrogenase YP_001943904.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1698 integrase, catalytic region YP_001943905.1 KEGG: rpa:RPA3927 possible phosphoheptose isomerase YP_001943906.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001943907.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1954 integrase, catalytic region YP_001943908.1 KEGG: sfr:Sfri_2831 hypothetical protein YP_001943909.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: dvl:Dvul_2644 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001943910.1 KEGG: sfr:Sfri_2831 hypothetical protein YP_001943911.1 KEGG: gvi:glr3782 unknown protein YP_001943912.1 KEGG: chu:CHU_2886 conserved hypothetical protein, possible O-antigen ligase-related YP_001943913.1 PFAM: Integrase catalytic region; KEGG: cph:Cpha266_1954 integrase, catalytic region YP_001943914.1 PFAM: transposase IS3/IS911 family protein; KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001943915.1 PFAM: S23 ribosomal protein; KEGG: cph:Cpha266_2609 S23 ribosomal protein YP_001943916.1 PFAM: glycosyl transferase family 4; KEGG: hch:HCH_02401 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase YP_001943917.1 KEGG: cph:Cpha266_2649 lipopolysaccharide biosynthesis; TIGRFAM: capsular exopolysaccharide family; PFAM: lipopolysaccharide biosynthesis protein YP_001943918.1 KEGG: plt:Plut_0763 hypothetical protein YP_001943919.1 KEGG: ppd:Ppro_0062 hypothetical protein YP_001943920.1 KEGG: hma:rrnAC2982 hypothetical protein YP_001943921.1 KEGG: sfu:Sfum_2196 hypothetical protein YP_001943922.1 KEGG: sfu:Sfum_2199 coenzyme PQQ synthesis D YP_001943924.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: sfu:Sfum_2197 radical SAM domain protein YP_001943925.1 PFAM: Radical SAM domain protein; KEGG: sfu:Sfum_2198 radical SAM domain protein YP_001943926.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: amr:AM1_1912 ABC transporter, ATP-binding/permease protein YP_001943929.1 KEGG: rpc:RPC_1817 hypothetical protein YP_001943931.1 KEGG: mba:Mbar_A2670 hypothetical protein YP_001943932.1 KEGG: cch:Cag_0645 hypothetical protein YP_001943934.1 KEGG: mba:Mbar_A2670 hypothetical protein YP_001943935.1 PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; KEGG: mba:Mbar_A0259 protease YP_001943936.1 KEGG: rrs:RoseRS_1019 hypothetical protein YP_001943937.1 PFAM: amidohydrolase; KEGG: bfr:BF4287 hypothetical protein YP_001943938.1 PFAM: fructose-bisphosphate aldolase class-I; KEGG: tbd:Tbd_1513 fructose-bisphosphate aldolase YP_001943939.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: pvi:Cvib_0955 iron-containing alcohol dehydrogenase YP_001943940.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_1427 protein of unknown function DUF1568 YP_001943941.1 PFAM: metallophosphoesterase; KEGG: plt:Plut_0506 Ser/Thr protein phosphatase family protein YP_001943942.1 PFAM: Domain of unknown function DUF1814; KEGG: plt:Plut_0508 hypothetical protein YP_001943943.1 KEGG: plt:Plut_0507 hypothetical protein YP_001943944.1 KEGG: plt:Plut_0506 Ser/Thr protein phosphatase family protein YP_001943945.1 binds and unfolds substrates as part of the ClpXP protease YP_001943946.1 KEGG: cph:Cpha266_0630 hypothetical protein YP_001943947.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001943948.1 PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: cph:Cpha266_0628 glutamate synthase (NADH) large subunit YP_001943949.1 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate YP_001943950.1 PFAM: 2-nitropropane dioxygenase NPD; KEGG: cph:Cpha266_0626 2-nitropropane dioxygenase, NPD YP_001943951.1 KEGG: cph:Cpha266_0625 hypothetical protein YP_001943952.1 KEGG: cph:Cpha266_1413 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001943953.1 PFAM: CMP/dCMP deaminase zinc-binding; KEGG: cph:Cpha266_0624 tRNA-adenosine deaminase YP_001943954.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001943955.1 PFAM: ABC transporter; protein of unknown function DUF214; SMART: AAA ATPase; KEGG: cph:Cpha266_0622 ABC transporter YP_001943956.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: cph:Cpha266_0621 efflux transporter, RND family, MFP subunit YP_001943957.1 PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0620 outer membrane efflux protein YP_001943959.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0618 ABC transporter YP_001943960.1 KEGG: cph:Cpha266_0617 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001943961.1 PFAM: small multidrug resistance protein; KEGG: cph:Cpha266_0616 small multidrug resistance protein YP_001943962.1 PFAM: oxidoreductase domain protein; Oxidoreductase domain; KEGG: cph:Cpha266_0615 oxidoreductase domain protein YP_001943963.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001943964.1 KEGG: cch:Cag_0286 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001943965.1 PFAM: protein of unknown function DUF985; KEGG: cte:CT0370 hypothetical protein YP_001943966.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cph:Cpha266_0611 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001943967.1 KEGG: cph:Cpha266_0610 hypothetical protein YP_001943968.1 catalyzes the formation of N-acetyl-l-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine YP_001943969.1 KEGG: cte:CT0366 hypothetical protein YP_001943970.1 KEGG: azo:azo1317 hypothetical protein YP_001943971.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: plt:Plut_1585 TonB-like YP_001943972.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: cph:Cpha266_0605 biopolymer transport protein ExbD/TolR YP_001943973.1 KEGG: cph:Cpha266_0604 hypothetical protein YP_001943974.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: cph:Cpha266_0603 MotA/TolQ/ExbB proton channel YP_001943975.1 KEGG: cph:Cpha266_0602 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger CHC2-family protein; TOPRIM domain protein; DNA primase catalytic core domain; SMART: Toprim sub domain protein YP_001943976.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001943977.1 KEGG: cph:Cpha266_0600 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II YP_001943978.1 PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: cph:Cpha266_0599 carbamoyl-phosphate synthase large subunit YP_001943979.1 KEGG: cph:Cpha266_1999 hypothetical protein YP_001943980.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_2000 short-chain dehydrogenase/reductase SDR YP_001943981.1 PFAM: ribulose bisphosphate carboxylase large chain; KEGG: plt:Plut_0412 ribulose-bisphosphate carboxylase YP_001943982.1 PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; KEGG: cph:Cpha266_0194 aldolase YP_001943983.1 PFAM: class II aldolase/adducin family protein; short-chain dehydrogenase/reductase SDR; KEGG: cph:Cpha266_0195 short chain dehydrogenase YP_001943984.1 KEGG: plt:Plut_0409 hypothetical protein YP_001943985.1 PFAM: 2-vinyl bacteriochlorophyllide hydratase; KEGG: plt:Plut_0408 2-vinyl bacteriochlorophyllide hydratase YP_001943986.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: plt:Plut_0407 elongator protein 3/MiaB/NifB YP_001943987.1 KEGG: cte:CT1620 hypothetical protein YP_001943988.1 PFAM: protein of unknown function DUF900 hydrolase family protein; KEGG: cph:Cpha266_2534 protein of unknown function DUF900, hydrolase family protein YP_001943989.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001943990.1 PFAM: hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: pvi:Cvib_1456 hypothetical protein YP_001943991.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cte:CT1701 iron-sulfur cluster-binding protein YP_001943992.1 TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: plt:Plut_1672 hypothetical protein YP_001943993.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_0508 methyltransferase type 12 YP_001943994.1 KEGG: cph:Cpha266_0507 cytochrome c YP_001943995.1 PFAM: peptidase M50; KEGG: cph:Cpha266_0506 peptidase M50 YP_001943996.1 KEGG: cph:Cpha266_0505 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS YP_001943997.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; SMCs flexible hinge domain protein; KEGG: cph:Cpha266_0504 chromosome segregation protein SMC YP_001943998.1 PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pvi:Cvib_1463 haloacid dehalogenase domain protein hydrolase YP_001943999.1 TIGRFAM: transcription antitermination factor NusB; PFAM: NusB/RsmB/TIM44; KEGG: cph:Cpha266_0502 NusB antitermination factor YP_001944000.1 PFAM: metallophosphoesterase; KEGG: cph:Cpha266_2593 metallophosphoesterase YP_001944001.1 KEGG: cph:Cpha266_0501 DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein YP_001944002.1 KEGG: cph:Cpha266_0500 hypothetical protein YP_001944003.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: cph:Cpha266_0499 para-aminobenzoate synthase, subunit I YP_001944004.1 PFAM: Ppx/GppA phosphatase; metal-dependent phosphohydrolase HD sub domain; KEGG: cph:Cpha266_0498 Ppx/GppA phosphatase YP_001944005.1 PFAM: phosphatidate cytidylyltransferase; KEGG: cph:Cpha266_0497 phosphatidate cytidylyltransferase YP_001944006.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5 domain protein; SUA5/yciO/yrdC domain; KEGG: cph:Cpha266_0496 translation factor SUA5 YP_001944007.1 KEGG: cph:Cpha266_0495 hypothetical protein YP_001944008.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: pvi:Cvib_1473 ribosomal large subunit pseudouridine synthase B YP_001944009.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: cph:Cpha266_0493 condensin subunit ScpB YP_001944010.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001944011.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001944012.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: cph:Cpha266_0490 ferredoxin--NADP(+) reductase subunit alpha YP_001944013.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_001944014.1 PFAM: CopG domain protein DNA-binding domain protein; NikR nickel binding; KEGG: cph:Cpha266_0488 CopG family transcriptional regulator YP_001944015.1 KEGG: cph:Cpha266_0487 hypothetical protein YP_001944016.1 PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: cph:Cpha266_0486 cobalamin (vitamin B12) biosynthesis CbiM protein YP_001944017.1 TIGRFAM: cobalt ABC transporter, inner membrane subunit CbiQ; PFAM: cobalt transport protein; KEGG: cph:Cpha266_0485 cobalt transport protein YP_001944018.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0484 ABC transporter YP_001944019.1 PFAM: protein of unknown function DUF88; KEGG: cph:Cpha266_0482 protein of unknown function DUF88 YP_001944020.1 PFAM: Auxin Efflux Carrier; KEGG: plt:Plut_1694 hypothetical protein YP_001944021.1 PFAM: ferrochelatase; KEGG: cph:Cpha266_0481 ferrochelatase YP_001944022.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: cph:Cpha266_0480 efflux transporter, RND family, MFP subunit YP_001944023.1 PR-AMP cyclohydrolase; functions in histidine biosynthesis from PRPP; converts 1-(5-phosphoribosyl)-AMP to 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxyamide during the histidine biosynthesis pathway; binds zinc and magnesium; forms homodimers YP_001944024.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferase; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_0478 demethylmenaquinone methyltransferase YP_001944025.1 KEGG: cph:Cpha266_0477 hypothetical protein YP_001944026.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_0476 conserved hypothetical protein 730 YP_001944027.1 KEGG: cte:CT0457 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase OB-fold; NAD-dependent DNA ligase adenylation; SMART: NAD-dependent DNA ligase YP_001944028.1 KEGG: cph:Cpha266_0474 hypothetical protein YP_001944029.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_0473 ABC transporter YP_001944030.1 PFAM: protein of unknown function UPF0153; KEGG: cph:Cpha266_0471 protein of unknown function UPF0153 YP_001944031.1 KEGG: cph:Cpha266_0470 hypothetical protein YP_001944032.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: cte:CT1724 arsenite efflux transporter YP_001944033.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: cph:Cpha266_0465 protein tyrosine phosphatase YP_001944034.1 PFAM: permease; KEGG: cte:CT1726 hypothetical protein YP_001944035.1 SMART: Rhodanese domain protein; KEGG: cph:Cpha266_0463 rhodanese domain protein YP_001944036.1 TIGRFAM: redox-active disulfide protein 2; KEGG: cch:Cag_0399 redox-active disulfide protein 2 YP_001944037.1 PFAM: regulatory protein ArsR; KEGG: cte:CT1728 ArsR family transcriptional regulator YP_001944038.1 PFAM: Secreted repeat of unknown function; KEGG: cph:Cpha266_0456 secreted repeat of unknown function YP_001944039.1 KEGG: cph:Cpha266_0786 DNA-binding protein YP_001944040.1 TIGRFAM: addiction module antidote protein, CC2985 family; PFAM: protein of unknown function UPF0156; KEGG: gvi:gsr2534 hypothetical protein YP_001944041.1 PFAM: plasmid stabilization system; KEGG: gvi:gsr3505 hypothetical protein YP_001944042.1 KEGG: plt:Plut_1397 invertase/recombinase like protein YP_001944043.1 TIGRFAM: chlorophyllide reductase subunit Y; PFAM: oxidoreductase/nitrogenase component 1; KEGG: cph:Cpha266_2075 chlorophyllide reductase subunit Y YP_001944044.1 KEGG: cte:CT1827 hypothetical protein YP_001944045.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001944046.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001944047.1 PFAM: D-tyrosyl-tRNA(Tyr) deacylase; KEGG: cph:Cpha266_2080 D-tyrosyl-tRNA(Tyr) deacylase YP_001944048.1 PFAM: protein of unknown function DUF167; KEGG: cph:Cpha266_2081 protein of unknown function DUF167 YP_001944049.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain YP_001944050.1 KEGG: cph:Cpha266_2083 citrate synthase; TIGRFAM: citrate synthase I; PFAM: Citrate synthase YP_001944051.1 PFAM: OmpA/MotB domain protein; KEGG: cph:Cpha266_2084 OmpA/MotB domain protein YP_001944052.1 KEGG: cph:Cpha266_2085 hypothetical protein YP_001944053.1 PFAM: Heavy metal transport/detoxification protein; KEGG: cph:Cpha266_2086 heavy metal transport/detoxification protein YP_001944054.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_2087 tetratricopeptide TPR_2 repeat protein YP_001944055.1 TIGRFAM: isochorismate synthase; PFAM: Chorismate binding-like; KEGG: cph:Cpha266_2088 isochorismate synthases YP_001944056.1 TIGRFAM: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase; PFAM: thiamine pyrophosphate protein TPP binding domain protein; KEGG: cph:Cpha266_2089 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase YP_001944057.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_2090 alpha/beta hydrolase fold YP_001944058.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001944059.1 PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: cph:Cpha266_2092 O-succinylbenzoate-CoA synthase YP_001944060.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2093 O-succinylbenzoate-CoA ligase YP_001944061.1 KEGG: cph:Cpha266_2094 hypothetical protein YP_001944062.1 PFAM: dihydrodipicolinate reductase; KEGG: plt:Plut_0324 dihydrodipicolinate reductase YP_001944063.1 TIGRFAM: parB-like partition protein; PFAM: ParB domain protein nuclease; KEGG: cph:Cpha266_2096 chromosome segregation DNA-binding protein YP_001944064.1 PFAM: Cobyrinic acid ac-diamide synthase; KEGG: cph:Cpha266_2097 chromosome segregation ATPase YP_001944065.1 TIGRFAM: DNA-3-methyladenine glycosylase; PFAM: methylpurine-DNA glycosylase (MPG); KEGG: cch:Cag_1802 methylpurine-DNA glycosylase (MPG) YP_001944066.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: cph:Cpha266_2099 magnesium transporter YP_001944067.1 PFAM: electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: plt:Plut_0319 electron-transferring-flavoprotein dehydrogenase YP_001944068.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001944069.1 PFAM: phospholipase/Carboxylesterase; KEGG: cph:Cpha266_2101 phospholipase/carboxylesterase YP_001944070.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001944071.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cch:Cag_0205 bacterioferritin comigratory protein, thiol peroxidase YP_001944072.1 KEGG: cph:Cpha266_2104 cytochrome c family protein YP_001944073.1 PFAM: cytochrome B561; KEGG: cph:Cpha266_2105 cytochrome b561 YP_001944075.1 KEGG: ppd:Ppro_0225 hypothetical protein YP_001944076.1 KEGG: cph:Cpha266_2141 hypothetical protein YP_001944077.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: cph:Cpha266_2142 peptidoglycan-binding domain 1 protein YP_001944078.1 KEGG: cph:Cpha266_2143 hypothetical protein YP_001944079.1 KEGG: pvi:Cvib_0378 hypothetical protein YP_001944080.1 PFAM: protein of unknown function DUF541; KEGG: cph:Cpha266_2145 protein of unknown function DUF541 YP_001944081.1 KEGG: cph:Cpha266_2146 hypothetical protein YP_001944082.1 KEGG: cph:Cpha266_2147 hypothetical protein YP_001944083.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: cph:Cpha266_2149 6-phosphogluconolactonase YP_001944084.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001944085.1 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate YP_001944086.1 KEGG: cph:Cpha266_2152 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-4 domain protein YP_001944087.1 PFAM: domain of unknown function DUF1745; KEGG: cph:Cpha266_2153 domain of unknown function DUF1745 YP_001944088.1 PFAM: protein of unknown function DUF541; KEGG: cph:Cpha266_2154 protein of unknown function DUF541 YP_001944089.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_2155 glycosyl transferase, group 1 YP_001944090.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: plt:Plut_0303 hypothetical protein YP_001944091.1 KEGG: cph:Cpha266_0309 outer surface protein YP_001944092.1 PFAM: Patatin; KEGG: cph:Cpha266_2157 patatin YP_001944093.1 PFAM: Aldehyde Dehydrogenase_; KEGG: cph:Cpha266_2158 aldehyde dehydrogenase YP_001944094.1 PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_2159 ABC transporter YP_001944095.1 PFAM: Integral membrane protein TerC; KEGG: cph:Cpha266_2160 integral membrane protein TerC YP_001944096.1 PFAM: peptidase S16 lon domain protein; KEGG: plt:Plut_0298 ATP-dependent protease YP_001944097.1 KEGG: cph:Cpha266_2161 UspA domain protein YP_001944098.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: cph:Cpha266_2163 tRNA/rRNA methyltransferase (SpoU) YP_001944099.1 KEGG: cph:Cpha266_2164 hypothetical protein YP_001944100.1 PFAM: peptidase U32; KEGG: cph:Cpha266_2165 peptidase U32 YP_001944101.1 KEGG: cph:Cpha266_2166 hydrogenase/sulfur reductase, beta subunit YP_001944102.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: cph:Cpha266_2167 oxidoreductase FAD/NAD(P)-binding domain protein YP_001944103.1 PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cph:Cpha266_2168 NADH ubiquinone oxidoreductase, 20 kDa subunit YP_001944104.1 PFAM: nickel-dependent hydrogenase large subunit; KEGG: cph:Cpha266_2169 nickel-dependent hydrogenase, large subunit YP_001944105.1 PFAM: DNA topoisomerase type IA zn finger domain protein; KEGG: cph:Cpha266_1210 DNA topoisomerase, type IA, zn finger domain protein YP_001944106.1 PFAM: Protein of unknown function DUF1778; KEGG: cph:Cpha266_1211 hypothetical protein YP_001944107.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cph:Cpha266_1212 GCN5-related N-acetyltransferase YP_001944108.1 KEGG: cph:Cpha266_2113 transposase IS3/IS911 family protein YP_001944109.1 KEGG: vha:VIBHAR_p08265 hypothetical protein YP_001944110.1 KEGG: cph:Cpha266_1222 superfamily I DNA and RNA helicase and helicase subunit YP_001944112.1 TIGRFAM: death-on-curing family protein; PFAM: Death-on-curing protein; KEGG: cph:Cpha266_2176 death-on-curing family protein YP_001944113.1 TIGRFAM: addiction module antidote; PFAM: SpoVT/AbrB domain protein; KEGG: cph:Cpha266_2175 tMazE family transcriptional regulator YP_001944114.1 KEGG: fjo:Fjoh_0971 hypothetical protein YP_001944116.1 PFAM: peptidylprolyl isomerase FKBP-type; KEGG: cph:Cpha266_2267 peptidylprolyl isomerase, FKBP-type YP_001944117.1 PFAM: MscS Mechanosensitive ion channel; KEGG: pvi:Cvib_0357 MscS mechanosensitive ion channel YP_001944118.1 PFAM: FAD dependent oxidoreductase; KEGG: cph:Cpha266_2269 FAD dependent oxidoreductase YP_001944119.1 KEGG: cph:Cpha266_2271 acetyltransferase, CysE/LacA/LpxA/NodL family YP_001944120.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cte:CT1901 ABC transporter, ATP-binding protein YP_001944121.1 PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cte:CT1903 BchE/P-methylase family protein YP_001944122.1 PFAM: RNP-1 like RNA-binding protein; KEGG: cch:Cag_1551 RNA-binding region RNP-1 (RNA recognition motif) YP_001944123.1 SMART: metal-dependent phosphohydrolase HD region; KEGG: cph:Cpha266_2274 metal dependent phosphohydrolase YP_001944124.1 KEGG: cph:Cpha266_2275 hypothetical protein YP_001944125.1 PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_2276 alpha/beta hydrolase fold YP_001944126.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001944127.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001944128.1 KEGG: cph:Cpha266_2279 hypothetical protein YP_001944129.1 PFAM: CBS domain containing protein; Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cph:Cpha266_2280 cysteine synthase YP_001944131.1 KEGG: cph:Cpha266_2284 alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase domain protein YP_001944132.1 SMART: Helix-hairpin-helix DNA-binding class 1; KEGG: cph:Cpha266_2285 helix-hairpin-helix motif YP_001944133.1 KEGG: cph:Cpha266_2286 hypothetical protein YP_001944134.1 TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; KEGG: cch:Cag_0282 aspartate-semialdehyde dehydrogenase, USG-1 related YP_001944135.1 TIGRFAM: TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase DuS; KEGG: plt:Plut_0276 dihydrouridine synthase TIM-barrel protein nifR3 YP_001944136.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001944137.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility domain; KR domain protein; KEGG: cph:Cpha266_2290 NAD-dependent epimerase/dehydratase YP_001944139.1 PFAM: peptidase M16 domain protein; KEGG: cph:Cpha266_2291 peptidase M16 domain protein YP_001944140.1 TIGRFAM: trigger factor; PFAM: trigger factor domain protein; trigger factor domain; KEGG: cph:Cpha266_2292 trigger factor YP_001944141.1 TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; KEGG: pvi:Cvib_0336 holo-acyl-carrier-protein synthase YP_001944142.1 KEGG: cph:Cpha266_2293 nicotinate-nucleotide pyrophosphorylase [carboxylating]; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001944143.1 TIGRFAM: dihydroneopterin aldolase; KEGG: cph:Cpha266_2294 dihydroneopterin aldolase YP_001944144.1 KEGG: plt:Plut_0268 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK YP_001944145.1 PFAM: transposase IS4 family protein; KEGG: amt:Amet_3130 transposase, IS4 family protein YP_001944146.1 KEGG: plt:Plut_0267 anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001944147.1 KEGG: cph:Cpha266_2298 hypothetical protein YP_001944148.1 PFAM: bacteriochlorophyll C binding protein; KEGG: pvi:Cvib_0330 bacteriochlorophyll C binding protein YP_001944149.1 KEGG: cph:Cpha266_2300 chlorosome envelope protein C YP_001944150.1 KEGG: cph:Cpha266_2301 arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001944151.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: cph:Cpha266_2302 dihydroorotate oxidase B, electron transfer subunit YP_001944152.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: cph:Cpha266_2303 single-strand binding protein YP_001944153.1 TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; KEGG: cph:Cpha266_2304 DNA polymerase III, delta subunit YP_001944154.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: cph:Cpha266_2305 NAD-dependent epimerase/dehydratase YP_001944155.1 PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cph:Cpha266_2306 8-amino-7-oxononanoate synthase YP_001944156.1 PFAM: TonB-dependent receptor; TonB-dependent receptor plug; KEGG: cph:Cpha266_2310 TonB-dependent receptor YP_001944157.1 KEGG: plt:Plut_0255 magnesium-chelatase, subunit H; TIGRFAM: magnesium chelatase, H subunit; PFAM: CobN/magnesium chelatase YP_001944158.1 KEGG: cph:Cpha266_2312 hypothetical protein YP_001944159.1 catalyzes the formation of Mg-protoporphyrin IX from protoporphyrin IX and Mg(2+); first committed step of chlorophyll biosynthesis YP_001944160.1 catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine YP_001944161.1 KEGG: cph:Cpha266_2315 magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; TIGRFAM: magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase; PFAM: cobalamin B12-binding domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001944162.1 PFAM: heat shock protein Hsp20; KEGG: cph:Cpha266_2316 heat shock protein HSP20 YP_001944163.1 PFAM: Hemolysin-type calcium-binding region; KEGG: cph:Cpha266_2335 hemolysin-type calcium-binding region YP_001944164.1 KEGG: cph:Cpha266_2351 hypothetical protein YP_001944165.1 KEGG: plt:Plut_0248 hypothetical protein YP_001944166.1 PFAM: Peptidase M23; KEGG: plt:Plut_0247 peptidase, M23/M37 family YP_001944167.1 PFAM: Class I peptide chain release factor; KEGG: vfi:VFA1155 hypothetical protein YP_001944168.1 KEGG: cph:Cpha266_1892 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001944169.1 PFAM: protein of unknown function DUF937; KEGG: cph:Cpha266_2353 protein of unknown function DUF937 YP_001944170.1 PFAM: hypothetical protein; KEGG: cph:Cpha266_2355 hypothetical protein YP_001944171.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_2356 glycosyl transferase, family 2 YP_001944172.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001944173.1 PFAM: metallophosphoesterase; KEGG: cph:Cpha266_2358 metallophosphoesterase YP_001944174.1 PFAM: phosphatidate cytidylyltransferase; KEGG: cph:Cpha266_2359 phosphatidate cytidylyltransferase YP_001944175.1 catalyzes the synthesis of bacteriochlorophyll c which is the primary pigment in the chlorosomes of the photosynthetic green bacteria YP_001944176.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001944177.1 PFAM: nitrogen-fixing NifU domain protein; BFD domain protein [2Fe-2S]-binding domain protein; KEGG: cph:Cpha266_2362 nitrogen-fixing NifU domain protein YP_001944178.1 PFAM: aminotransferase class V; KEGG: pvi:Cvib_0301 aminotransferase, class V YP_001944179.1 TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: cph:Cpha266_2364 cysteine synthase YP_001944180.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: cph:Cpha266_2365 short-chain dehydrogenase/reductase SDR YP_001944181.1 KEGG: cph:Cpha266_2366 helix-turn-helix domain protein YP_001944182.1 KEGG: plt:Plut_0232 hypothetical protein YP_001944183.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001944184.1 PFAM: protein of unknown function UPF0118; KEGG: pvi:Cvib_0294 protein of unknown function UPF0118 YP_001944185.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001944186.1 PFAM: phosphoribosyltransferase; KEGG: cph:Cpha266_2371 phosphoribosyltransferase YP_001944187.1 PFAM: ROK family protein; KEGG: cph:Cpha266_2372 ROK family protein YP_001944188.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001944189.1 KEGG: cph:Cpha266_2374 hypothetical protein YP_001944190.1 KEGG: cph:Cpha266_2375 oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001944191.1 TIGRFAM: histidinol-phosphate phosphatase family protein; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Polynucleotide kinase 3 phosphatase central region; KEGG: cph:Cpha266_2376 histidinol-phosphate phosphatase family protein YP_001944192.1 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose YP_001944193.1 KEGG: cph:Cpha266_2378 hypothetical protein YP_001944194.1 TIGRFAM: bacteriochlorophyll 4-vinyl reductase; KEGG: cph:Cpha266_2379 bacteriochlorophyll 4-vinyl reductase YP_001944195.1 light-independent; with chlN(bchN) and chlB(bchB) reduces ring D of protochlorophyllide to form chlorophyllide a in chlorophyll/bacteriochlorophyll production YP_001944196.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001944197.1 light-independent reduction of protochlorophyllide to form chlorophyllide a YP_001944198.1 PFAM: protein of unknown function DUF77; KEGG: cph:Cpha266_2389 protein of unknown function DUF77 YP_001944199.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001944200.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001944201.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001944202.1 PFAM: Nucleotidyl transferase; KEGG: cph:Cpha266_2393 mannose-1-phosphate guanylyltransferase (GDP) YP_001944203.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001944204.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001944205.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001944206.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001944207.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001944208.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001944209.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001944210.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001944211.1 TIGRFAM: methionine aminopeptidase, type I; PFAM: peptidase M24; KEGG: cph:Cpha266_2402 methionine aminopeptidase, type I YP_001944212.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001944213.1 late assembly protein YP_001944214.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_001944215.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001944216.1 binds 5S rRNA along with protein L5 and L25 YP_001944217.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001944218.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001944219.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001944220.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001944221.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001944222.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001944223.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001944224.1 one of the stabilizing components for the large ribosomal subunit YP_001944225.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001944226.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001944227.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001944228.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001944229.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001944230.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001944231.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001944232.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001944233.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001944234.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001944235.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001944236.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001944237.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001944238.1 KEGG: cph:Cpha266_2429 hypothetical protein YP_001944239.1 PFAM: acid phosphatase (Class B); KEGG: cph:Cpha266_1069 acid phosphatase (class B) YP_001944240.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; NmrA family protein; Male sterility domain; KEGG: cph:Cpha266_1679 3-beta hydroxysteroid dehydrogenase/isomerase YP_001944241.1 PFAM: cell division protein FtsA; cell shape determining protein MreB/Mrl; KEGG: cte:CT1470 rod shape-determining protein MreB YP_001944242.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein; KEGG: plt:Plut_1478 PhnA protein YP_001944243.1 PFAM: GTPase EngC; KEGG: cph:Cpha266_1597 GTPase EngC YP_001944244.1 KEGG: lin:lin2171 hypothetical protein YP_001944245.1 TIGRFAM: mobile mystery protein B; PFAM: filamentation induced by cAMP protein Fic; KEGG: gsu:GSU1391 Fic family protein YP_001944246.1 TIGRFAM: mobile mystery protein A; PFAM: helix-turn-helix domain protein; KEGG: plt:Plut_1905 XRE family transcriptional regulator YP_001944247.1 KEGG: cph:Cpha266_1473 hypothetical protein YP_001944248.1 KEGG: cph:Cpha266_1474 hypothetical protein YP_001944249.1 PFAM: nitroreductase; KEGG: cph:Cpha266_1469 nitroreductase YP_001944250.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: pvi:Cvib_1055 methyltransferase type 12 YP_001944251.1 PFAM: thioesterase superfamily protein; KEGG: cph:Cpha266_1470 uncharacterized domain 1 YP_001944253.1 PFAM: Lytic transglycosylase catalytic; KEGG: bfr:BF3910 phage-related protein YP_001944254.1 KEGG: cph:Cpha266_1471 hypothetical protein YP_001944256.1 KEGG: cph:Cpha266_1472 hypothetical protein YP_001944257.1 KEGG: aci:ACIAD1306 conserved hypothetical protein; signal peptide YP_001944258.1 KEGG: cph:Cpha266_1475 hypothetical protein YP_001944259.1 KEGG: mxa:MXAN_6313 lipoprotein YP_001944260.1 PFAM: regulatory protein ArsR; KEGG: cph:Cpha266_1489 regulatory protein, ArsR YP_001944261.1 KEGG: psb:Psyr_0104 hypothetical protein YP_001944262.1 KEGG: ses:SARI_03320 hypothetical protein YP_001944263.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001944264.1 KEGG: kpn:KPN_02945 hypothetical protein YP_001944265.1 KEGG: fnu:FN1319 DNA primase YP_001944266.1 KEGG: hch:HCH_03582 hypothetical protein YP_001944269.1 KEGG: cte:CT1692 hypothetical protein YP_001944270.1 KEGG: cph:Cpha266_1501 hypothetical protein YP_001944271.1 KEGG: pca:Pcar_2730 ATP-dependent DNA helicase YP_001944272.1 KEGG: bja:bll8207 hypothetical protein YP_001944273.1 PFAM: Hemolysin-type calcium-binding region; KEGG: bpl:BURPS1106A_2063 type I secretion target repeat protein YP_001944274.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001944275.1 PFAM: Hemolysin-type calcium-binding region; lipase class 3; FG-GAP repeat protein; SMART: Integrin alpha beta-propellor repeat protein; KEGG: gvi:glr1840 hypothetical protein YP_001944276.1 PFAM: outer membrane efflux protein; KEGG: prw:PsycPRwf_0759 outer membrane efflux protein YP_001944277.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: prw:PsycPRwf_0760 ABC transporter YP_001944278.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: prw:PsycPRwf_0761 type I secretion membrane fusion protein, HlyD family YP_001944279.1 KEGG: cph:Cpha266_2437 hypothetical protein YP_001944280.1 PFAM: polysaccharide biosynthesis protein; KEGG: cph:Cpha266_2438 polysaccharide biosynthesis protein YP_001944281.1 KEGG: cph:Cpha266_2439 glycosyl transferase, group 1 YP_001944282.1 KEGG: cph:Cpha266_2440 hypothetical protein YP_001944283.1 PFAM: glycosyl transferase family 2; KEGG: cph:Cpha266_2441 glycosyl transferase, family 2 YP_001944284.1 PFAM: glycosyl transferase group 1; KEGG: cph:Cpha266_2442 glycosyl transferase, group 1 YP_001944285.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: cph:Cpha266_2443 phosphotransferase system, phosphocarrier protein HPr YP_001944286.1 catalyzes the formation of N-acetyl-L-glutamate from acetyl-CoA and L-glutamate YP_001944287.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001944288.1 PFAM: Exonuclease VII small subunit; KEGG: cph:Cpha266_2446 exodeoxyribonuclease VII small subunit YP_001944289.1 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA YP_001944290.1 KEGG: cph:Cpha266_2448 hypothetical protein YP_001944291.1 PFAM: ATPase AAA; Clp domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2449 AAA ATPase, central domain protein YP_001944292.1 KEGG: cph:Cpha266_2450 hypothetical protein YP_001944293.1 PFAM: von Willebrand factor type A; KEGG: cph:Cpha266_2451 von Willebrand factor, type A YP_001944294.1 PFAM: von Willebrand factor type A; KEGG: cph:Cpha266_2452 von Willebrand factor, type A YP_001944295.1 KEGG: cph:Cpha266_2453 hypothetical protein YP_001944296.1 PFAM: protein of unknown function DUF58; SMART: von Willebrand factor type A; KEGG: cph:Cpha266_2454 protein of unknown function DUF58 YP_001944297.1 PFAM: ATPase associated with various cellular activities AAA_3; ATPase associated with various cellular activities AAA_5; KEGG: cph:Cpha266_2455 ATPase associated with various cellular activities, AAA_3 YP_001944298.1 KEGG: cph:Cpha266_2456 hypothetical protein YP_001944299.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001944300.1 TIGRFAM: preprotein translocase subunit YajC; PFAM: YajC family protein; KEGG: cph:Cpha266_2458 protein translocase subunit YajC YP_001944301.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001944302.1 PFAM: aminotransferase class V; KEGG: cph:Cpha266_2460 serine--glyoxylate transaminase YP_001944303.1 KEGG: cph:Cpha266_2461 hypothetical protein YP_001944304.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: cph:Cpha266_2462 radical SAM domain protein YP_001944305.1 PFAM: cytochrome c class I; KEGG: cph:Cpha266_2463 cytochrome c, class I YP_001944306.1 PFAM: cytochrome c class I; KEGG: cph:Cpha266_2464 cytochrome c, class I YP_001944307.1 KEGG: cph:Cpha266_2465 MtN3 and saliva related transmembrane protein YP_001944308.1 KEGG: cph:Cpha266_2466 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001944309.1 KEGG: cph:Cpha266_2467 hypothetical protein YP_001944310.1 TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; KEGG: cph:Cpha266_2468 molybdopterin molybdochelatase YP_001944311.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001944312.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: cph:Cpha266_2470 glycerophosphoryl diester phosphodiesterase YP_001944313.1 KEGG: plt:Plut_0145 hypothetical protein YP_001944314.1 KEGG: plt:Plut_0144 Ric1 protein YP_001944315.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis; MobB is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_001944316.1 PFAM: UspA domain protein; KEGG: pvi:Cvib_0209 UspA domain protein YP_001944317.1 PFAM: transport system permease protein; ABC transporter; KEGG: cph:Cpha266_2474 ABC transporter YP_001944318.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: cph:Cpha266_2475 ABC transporter YP_001944319.1 PFAM: periplasmic solute binding protein; KEGG: cte:CT2106 adhesion protein YP_001944320.1 PFAM: ferric-uptake regulator; KEGG: cph:Cpha266_2477 ferric uptake regulator, Fur family YP_001944321.1 TIGRFAM: 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; KEGG: cph:Cpha266_2478 2-isopropylmalate synthase YP_001944322.1 PFAM: protein of unknown function DUF306 Meta and HslJ; KEGG: pvi:Cvib_0204 protein of unknown function DUF306, MetA and HslJ YP_001944323.1 PFAM: ABC transporter; KEGG: mba:Mbar_A2485 hypothetical protein YP_001944324.1 PFAM: ABC transporter; SMART: AAA ATPase; KEGG: mhu:Mhun_0242 daunorubicin resistance ABC transporter ATP-binding subunit YP_001944325.1 KEGG: pca:Pcar_2840 hypothetical protein YP_001944326.1 PFAM: regulatory protein ArsR; Helix-turn-helix type 11 domain protein; KEGG: pca:Pcar_2839 predicted metal-regulated homodimeric transcriptional regulator YP_001944327.1 KEGG: cph:Cpha266_0169 hypothetical protein YP_001944328.1 TIGRFAM: monofunctional biosynthetic peptidoglycan transglycosylase; PFAM: glycosyl transferase family 51; KEGG: cch:Cag_0146 monofunctional biosynthetic peptidoglycan transglycosylase YP_001944329.1 PFAM: cytochrome c class I; KEGG: cph:Cpha266_0171 C-type cytochrome YP_001944330.1 TIGRFAM: DNA mismatch repair protein MutL; PFAM: ATP-binding region ATPase domain protein; DNA mismatch repair protein domain protein; MutL dimerisation; KEGG: cph:Cpha266_0172 DNA mismatch repair protein MutL YP_001944331.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: cph:Cpha266_2541 competence/damage-inducible protein CinA YP_001944332.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001944333.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the gamma chain is a regulatory subunit YP_001944334.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001944335.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001944336.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001944337.1 KEGG: cph:Cpha266_2547 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase YP_001944338.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001944339.1 TIGRFAM: phosphoheptose isomerase; KEGG: cph:Cpha266_2549 phosphoheptose isomerase YP_001944340.1 PFAM: UspA domain protein; KEGG: cph:Cpha266_2551 UspA domain protein YP_001944341.1 PFAM: Ion transport protein; Ion transport 2 domain protein; KEGG: pvi:Cvib_1634 ion transport protein YP_001944343.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001944344.1 PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cph:Cpha266_0175 succinate dehydrogenase subunit C YP_001944345.1 TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; KEGG: cph:Cpha266_0176 succinate dehydrogenase subunit B YP_001944346.1 KEGG: cph:Cpha266_0177 succinate dehydrogenase subunit A; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001944347.1 PFAM: CBS domain containing protein; KEGG: cch:Cag_0126 CBS YP_001944348.1 PFAM: beta-lactamase domain protein; KEGG: cph:Cpha266_0179 beta-lactamase domain protein YP_001944349.1 KEGG: cph:Cpha266_0180 hypothetical protein YP_001944350.1 PFAM: acriflavin resistance protein; KEGG: cph:Cpha266_0181 acriflavin resistance protein YP_001944351.1 KEGG: plt:Plut_2000 hypothetical protein YP_001944352.1 PFAM: outer membrane efflux protein; KEGG: cph:Cpha266_0183 outer membrane efflux protein YP_001944353.1 PFAM: protein of unknown function DUF156; KEGG: cph:Cpha266_0184 hypothetical protein YP_001944354.1 KEGG: plt:Plut_2003 hypothetical protein YP_001944355.1 KEGG: plt:Plut_2004 hypothetical protein YP_001944356.1 KEGG: plt:Plut_2005 chlorosome envelope protein B YP_001944357.1 PFAM: aminoglycoside phosphotransferase; KEGG: cph:Cpha266_0203 aminoglycoside phosphotransferase YP_001944358.1 PFAM: Nucleotidyl transferase; KEGG: cph:Cpha266_0204 nucleotidyl transferase YP_001944359.1 PFAM: conserved hypothetical protein; KEGG: cph:Cpha266_0205 uncharacterised conserved protein UCP016719 YP_001944360.1 PFAM: Na+/solute symporter; KEGG: cph:Cpha266_0206 Na+/solute symporter YP_001944361.1 PFAM: bacteriochlorophyll C binding protein; KEGG: plt:Plut_2013 chlorosome envelope protein E YP_001944362.1 PFAM: NAD-dependent epimerase/dehydratase; NmrA family protein; KEGG: cph:Cpha266_0208 NAD-dependent epimerase/dehydratase YP_001944363.1 PFAM: pentapeptide repeat protein; KEGG: cph:Cpha266_0209 pentapeptide repeat protein YP_001944364.1 KEGG: pvi:Cvib_1657 hypothetical protein YP_001944365.1 KEGG: cph:Cpha266_0211 hypothetical protein YP_001944366.1 KEGG: cph:Cpha266_0213 arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase YP_001944367.1 PFAM: hypothetical protein; hypothetical protein; SMART: Tetratricopeptide domain protein; KEGG: cph:Cpha266_0214 tetratricopeptide TPR_2 repeat protein YP_001944368.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: cph:Cpha266_0215 rare lipoprotein A YP_001944369.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: plt:Plut_2020 rare lipoprotein A YP_001944370.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cte:CT2121 methyltransferase YP_001944371.1 PFAM: conserved hypothetical protein; KEGG: bpt:Bpet4723 lysine decarboxylase YP_001944372.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: fjo:Fjoh_2091 short-chain dehydrogenase/reductase SDR YP_001944373.1 PFAM: YceI family protein; KEGG: gme:Gmet_3449 YceI YP_001944374.1 KEGG: sfu:Sfum_2080 hypothetical protein YP_001944375.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001944376.1 PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: cph:Cpha266_0152 short-chain dehydrogenase/reductase SDR YP_001944377.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001944379.1 PFAM: phospholipase/Carboxylesterase; KEGG: cph:Cpha266_2535 phospholipase/carboxylesterase YP_001944380.1 KEGG: cph:Cpha266_2536 trehalose synthase; TIGRFAM: trehalose synthase; trehalose synthase-fused possible maltokinase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain YP_001944381.1 PFAM: alpha amylase catalytic region; KEGG: cph:Cpha266_2537 alpha amylase, catalytic region YP_001944382.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: cph:Cpha266_2538 bacterial peptide chain release factor 2 (bRF-2) YP_001944383.1 PFAM: metallophosphoesterase; KEGG: cph:Cpha266_2539 hypothetical protein YP_001944384.1 PFAM: Peptidase M23; KEGG: plt:Plut_2033 membrane proteins related to metalloendopeptidase-like YP_001944386.1 PFAM: Radical SAM domain protein; KEGG: cph:Cpha266_1175 radical SAM domain protein YP_001944387.1 PFAM: OmpA/MotB domain protein; KEGG: cph:Cpha266_2107 OmpA/MotB domain protein YP_001944388.1 KEGG: lch:Lcho_4189 hypothetical protein YP_001944390.1 KEGG: cph:Cpha266_1987 hypothetical protein YP_001944391.1 PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: cph:Cpha266_2553 UDP-N-acetylglucosamine 2-epimerase YP_001944392.1 PFAM: OstA family protein; KEGG: cph:Cpha266_2554 hypothetical protein YP_001944393.1 TIGRFAM: regulatory protein, FmdB family; PFAM: regulatory protein FmdB; KEGG: cph:Cpha266_2555 regulatory protein, FmdB family YP_001944394.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O RecO; KEGG: cph:Cpha266_2556 DNA repair protein RecO YP_001944395.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001944396.1 KEGG: bch:Bcen2424_3497 hypothetical protein YP_001944397.1 PFAM: protein of unknown function DUF190; KEGG: cte:CT2101 hypothetical protein YP_001944398.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001944399.1 KEGG: cph:Cpha266_2560 hypothetical protein YP_001944400.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: cph:Cpha266_2562 formate dehydrogenase YP_001944401.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_2563 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001944402.1 PFAM: Polysulphide reductase NrfD; KEGG: cph:Cpha266_2564 polysulphide reductase, NrfD YP_001944403.1 KEGG: cph:Cpha266_1687 hypothetical protein YP_001944405.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cph:Cpha266_2569 sulfide-quinone reductase YP_001944406.1 PFAM: Holliday junction resolvase YqgF; SMART: Resolvase RNase H domain protein fold; KEGG: cph:Cpha266_2570 Holliday junction resolvase YqgF YP_001944407.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001944408.1 PFAM: Prephenate dehydrogenase; KEGG: cph:Cpha266_2572 prephenate dehydrogenase YP_001944409.1 PFAM: ATP-NAD/AcoX kinase; KEGG: cph:Cpha266_2573 NAD(+) kinase YP_001944410.1 KEGG: cph:Cpha266_2574 hypothetical protein YP_001944411.1 TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; KEGG: cph:Cpha266_2575 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_001944412.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001944413.1 PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2577 ATPase AAA-2 domain protein YP_001944414.1 PFAM: glycoside hydrolase family 3 domain protein; KEGG: cph:Cpha266_2578 glycoside hydrolase, family 3 domain protein YP_001944415.1 PFAM: Phosphoglycerate mutase; KEGG: cph:Cpha266_2579 phosphohistidine phosphatase, SixA YP_001944416.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001944417.1 PFAM: protein of unknown function DUF205; KEGG: cph:Cpha266_2581 acyl-phosphate glycerol-3-phosphate acyltransferase YP_001944418.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001944419.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001944420.1 PFAM: NLP/P60 protein; KEGG: cph:Cpha266_2584 NLP/P60 protein YP_001944421.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001944422.1 PFAM: Ppx/GppA phosphatase; KEGG: cph:Cpha266_2586 Ppx/GppA phosphatase YP_001944423.1 KEGG: cph:Cpha266_2587 hypothetical protein YP_001944424.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase YP_001944425.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: cph:Cpha266_0117 aminotransferase YP_001944426.1 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium YP_001944427.1 TIGRFAM: biotin biosynthesis protein BioC; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: cph:Cpha266_0115 biotin biosynthesis protein BioC YP_001944428.1 PFAM: protein of unknown function DUF452; KEGG: cph:Cpha266_0114 protein of unknown function DUF452 YP_001944429.1 PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_0113 8-amino-7-oxononanoate synthase YP_001944430.1 KEGG: cte:CT0052 biotin synthetase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001944431.1 KEGG: cph:Cpha266_0111 biotin--acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; Helix-turn-helix type 11 domain protein YP_001944432.1 PFAM: cell wall hydrolase/autolysin; KEGG: cph:Cpha266_0110 N-acetylmuramoyl-L-alanine amidase YP_001944433.1 KEGG: cph:Cpha266_0109 DNA topoisomerase I; TIGRFAM: DNA topoisomerase I; PFAM: TOPRIM domain protein; DNA topoisomerase type IA central domain protein; DNA topoisomerase type IA zn finger domain protein; SMART: DNA topoisomerase I ATP-binding; DNA topoisomerase I DNA-binding; Toprim sub domain protein YP_001944434.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; KEGG: cph:Cpha266_0108 ferrous iron transport protein B YP_001944435.1 PFAM: FeoA family protein; KEGG: cph:Cpha266_0107 FeoA family protein YP_001944436.1 TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein; KEGG: cph:Cpha266_0106 aconitase YP_001944437.1 PFAM: histidine triad (HIT) protein; KEGG: cph:Cpha266_0105 histidine triad (HIT) protein YP_001944438.1 KEGG: cph:Cpha266_0104 hypothetical protein YP_001944439.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: cph:Cpha266_0098 protein of unknown function DUF21 YP_001944440.1 KEGG: plt:Plut_2079 Fibrobacter succinogenes major paralogous domain YP_001944441.1 PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_0100 succinate dehydrogenase/fumarate reductase iron-sulfur subunit YP_001944442.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001944443.1 TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family; KEGG: cph:Cpha266_0102 succinate dehydrogenase subunit C YP_001944444.1 PFAM: cyclase family protein; KEGG: cph:Cpha266_0103 cyclase family protein YP_001944445.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001944446.1 KEGG: nfa:nfa2750 hypothetical protein YP_001944447.1 PFAM: Alkaline phosphatase; KEGG: cph:Cpha266_2693 alkaline phosphatase YP_001944448.1 KEGG: cph:Cpha266_2695 hypothetical protein YP_001944449.1 PFAM: alpha/beta hydrolase fold; KEGG: pvi:Cvib_1726 alpha/beta hydrolase fold YP_001944450.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; KEGG: cph:Cpha266_2697 rare lipoprotein A YP_001944451.1 KEGG: cph:Cpha266_1071 hypothetical protein YP_001944452.1 PFAM: protein of unknown function DUF89; KEGG: cph:Cpha266_1577 protein of unknown function DUF89 YP_001944453.1 PFAM: protein of unknown function DUF1568; KEGG: cph:Cpha266_1578 protein of unknown function DUF1568 YP_001944454.1 KEGG: sgr:SGR_4270 hypothetical protein YP_001944455.1 KEGG: swi:Swit_0248 hypothetical protein YP_001944456.1 KEGG: cph:Cpha266_1691 hypothetical protein YP_001944458.1 KEGG: rpe:RPE_2427 hypothetical protein YP_001944459.1 KEGG: swi:Swit_1093 hypothetical protein YP_001944460.1 KEGG: cph:Cpha266_1705 protein of unknown function DUF559; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; protein of unknown function DUF559; SMART: DEAD-like helicases YP_001944461.1 PFAM: AAA-4 family protein; KEGG: cph:Cpha266_1706 transcriptional regulator YP_001944462.1 KEGG: nmu:Nmul_A0110 hypothetical protein YP_001944463.1 PFAM: transposase IS4 family protein; KEGG: cph:Cpha266_2634 transposase, IS4 family protein YP_001944464.1 PFAM: protein of unknown function DUF87; KEGG: pst:PSPTO_4332 hypothetical protein YP_001944465.1 KEGG: pst:PSPTO_4326 hypothetical protein YP_001944466.1 PFAM: restriction modification system DNA specificity domain; KEGG: tcx:Tcr_0333 restriction modification system DNA specificity domain YP_001944467.1 KEGG: cph:Cpha266_1711 DNA-damage-inducible protein D YP_001944468.1 PFAM: N-6 DNA methylase; KEGG: cph:Cpha266_1712 N-6 DNA methylase YP_001944470.1 PFAM: Domain of unknown function DUF1828; KEGG: cph:Cpha266_1713 conserved hypothetical cytosolic protein YP_001944471.1 KEGG: cph:Cpha266_1714 hypothetical protein YP_001944472.1 KEGG: cph:Cpha266_1716 hypothetical protein YP_001944473.1 KEGG: mrd:Mrad2831_6506 hypothetical protein YP_001944474.1 KEGG: cph:Cpha266_1504 PIN domain protein YP_001944475.1 PFAM: protein of unknown function DUF955; KEGG: cph:Cpha266_1505 protein of unknown function DUF955 YP_001944476.1 KEGG: cph:Cpha266_2705 hypothetical protein YP_001944477.1 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity YP_001944478.1 transforms a conserved lysine residue of initiation factor 5A into deoxyhypusine YP_001944480.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001944481.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; beta-phosphoglucomutase family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pvi:Cvib_1731 beta-phosphoglucomutase family hydrolase YP_001944482.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001944483.1 TIGRFAM: cytidyltransferase-related domain protein; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; KEGG: cph:Cpha266_2703 nicotinate (nicotinamide) nucleotide adenylyltransferase YP_001944484.1 KEGG: cph:Cpha266_2704 lipoprotein YP_001944485.1 KEGG: cph:Cpha266_0683 hypothetical protein YP_001944486.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001944487.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001944488.1 TIGRFAM: ATP synthase F0, C subunit; PFAM: H+transporting two-sector ATPase C subunit; KEGG: plt:Plut_2097 ATP synthase F0, C subunit YP_001944489.1 KEGG: plt:Plut_2099 hypothetical protein YP_001944490.1 KEGG: pvi:Cvib_1745 hypothetical protein YP_001944491.1 PFAM: protein of unknown function DUF152; KEGG: cph:Cpha266_2712 protein of unknown function DUF152 YP_001944492.1 KEGG: cte:CT0027 hypothetical protein YP_001944493.1 TIGRFAM: C-20 methyltransferase BchU; PFAM: O-methyltransferase family 2; KEGG: cph:Cpha266_2714 O-methyltransferase, family 2 YP_001944494.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: cte:CT0029 4-hydroxybutyrate coenzyme A transferase YP_001944495.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001944496.1 PFAM: cell division protein FtsA; KEGG: cph:Cpha266_2717 cell division protein FtsA YP_001944497.1 PFAM: Polypeptide-transport-associated domain protein FtsQ-type; KEGG: cph:Cpha266_2718 polypeptide-transport-associated domain protein, FtsQ-type YP_001944498.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001944499.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001944500.1 PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein YP_001944501.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001944502.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001944503.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_2725 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase YP_001944504.1 TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: cph:Cpha266_2726 UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase YP_001944505.1 PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cph:Cpha266_2727 peptidoglycan glycosyltransferase YP_001944506.1 KEGG: cph:Cpha266_2728 hypothetical protein YP_001944507.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: cph:Cpha266_2729 S-adenosyl-methyltransferase MraW YP_001944508.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001944509.1 KEGG: cph:Cpha266_2731 hypothetical protein YP_001944510.1 PFAM: Chorismate mutase; KEGG: cph:Cpha266_2732 chorismate mutase YP_001944511.1 PFAM: aminodeoxychorismate lyase; KEGG: cph:Cpha266_2733 aminodeoxychorismate lyase YP_001944512.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001944513.1 PFAM: Rhomboid family protein; KEGG: cph:Cpha266_2735 rhomboid family protein YP_001944514.1 PFAM: protein of unknown function DUF1232; KEGG: plt:Plut_2125 hypothetical protein YP_001944515.1 TIGRFAM: RNA methyltransferase, TrmA family; PFAM: RNA methylase; deoxyribonuclease/rho motif-related TRAM; (Uracil-5)-methyltransferase; KEGG: cte:CT0009 RNA methyltransferase, TrmA family YP_001944516.1 PFAM: ROK family protein; KEGG: cph:Cpha266_2738 N-acetylglucosamine kinase YP_001944517.1 PFAM: phosphoesterase PA-phosphatase related; KEGG: pvi:Cvib_1770 phosphoesterase, PA-phosphatase related YP_001944518.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: cph:Cpha266_2740 protein translocase subunit YidC YP_001944519.1 PFAM: protein of unknown function DUF37; KEGG: cph:Cpha266_2741 protein of unknown function DUF37 YP_001944520.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001944521.1 PFAM: ribosomal protein L34; KEGG: plt:Plut_2132 50S ribosomal protein L34