-- dump date   	20140619_042548
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
1128398000001	Replication protein; Region: Rep_1; cl02412
1128398000002	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
1128398000003	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1128398000004	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398000005	Walker A motif; other site
1128398000006	ATP binding site [chemical binding]; other site
1128398000007	Walker B motif; other site
1128398000008	arginine finger; other site
1128398000009	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
1128398000010	DnaA box-binding interface [nucleotide binding]; other site
1128398000011	DNA polymerase III subunit beta; Validated; Region: PRK05643
1128398000012	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
1128398000013	putative DNA binding surface [nucleotide binding]; other site
1128398000014	dimer interface [polypeptide binding]; other site
1128398000015	beta-clamp/clamp loader binding surface; other site
1128398000016	beta-clamp/translesion DNA polymerase binding surface; other site
1128398000017	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398000018	RNA binding surface [nucleotide binding]; other site
1128398000019	recombination protein F; Reviewed; Region: recF; PRK00064
1128398000020	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
1128398000021	Walker A/P-loop; other site
1128398000022	ATP binding site [chemical binding]; other site
1128398000023	Q-loop/lid; other site
1128398000024	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398000025	ABC transporter signature motif; other site
1128398000026	Walker B; other site
1128398000027	D-loop; other site
1128398000028	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
1128398000029	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000030	Mg2+ binding site [ion binding]; other site
1128398000031	G-X-G motif; other site
1128398000032	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
1128398000033	anchoring element; other site
1128398000034	dimer interface [polypeptide binding]; other site
1128398000035	ATP binding site [chemical binding]; other site
1128398000036	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
1128398000037	active site
1128398000038	putative metal-binding site [ion binding]; other site
1128398000039	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
1128398000040	DNA gyrase subunit A; Validated; Region: PRK05560
1128398000041	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
1128398000042	CAP-like domain; other site
1128398000043	active site
1128398000044	primary dimer interface [polypeptide binding]; other site
1128398000045	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000046	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000047	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000048	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000049	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000050	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
1128398000051	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1128398000052	anti sigma factor interaction site; other site
1128398000053	regulatory phosphorylation site [posttranslational modification]; other site
1128398000054	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1128398000055	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000056	ATP binding site [chemical binding]; other site
1128398000057	Mg2+ binding site [ion binding]; other site
1128398000058	G-X-G motif; other site
1128398000059	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
1128398000060	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398000061	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1128398000062	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398000063	DNA binding residues [nucleotide binding]
1128398000064	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1128398000065	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1128398000066	ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: COG3638
1128398000067	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1128398000068	Walker A/P-loop; other site
1128398000069	ATP binding site [chemical binding]; other site
1128398000070	Q-loop/lid; other site
1128398000071	ABC transporter signature motif; other site
1128398000072	Walker B; other site
1128398000073	D-loop; other site
1128398000074	H-loop/switch region; other site
1128398000075	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1128398000076	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
1128398000077	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1128398000078	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398000079	dimer interface [polypeptide binding]; other site
1128398000080	conserved gate region; other site
1128398000081	putative PBP binding loops; other site
1128398000082	ABC-ATPase subunit interface; other site
1128398000083	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398000084	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398000085	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
1128398000086	Quinolinate synthetase A protein; Region: NadA; pfam02445
1128398000087	L-aspartate oxidase; Provisional; Region: PRK06175
1128398000088	Aspartate oxidase [Coenzyme metabolism]; Region: NadB; COG0029
1128398000089	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1128398000090	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1128398000091	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
1128398000092	dimerization interface [polypeptide binding]; other site
1128398000093	active site
1128398000094	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
1128398000095	HTH domain; Region: HTH_11; pfam08279
1128398000096	3H domain; Region: 3H; pfam02829
1128398000097	Predicted membrane protein, putative toxin regulator [General function prediction only]; Region: PfoR; COG3641
1128398000098	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
1128398000099	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398000100	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398000101	metal binding site [ion binding]; metal-binding site
1128398000102	active site
1128398000103	I-site; other site
1128398000104	Small acid-soluble spore protein H family; Region: SspH; cl06949
1128398000105	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
1128398000106	guanine deaminase; Region: guan_deamin; TIGR02967
1128398000107	active site
1128398000108	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1128398000109	seryl-tRNA synthetase; Provisional; Region: PRK05431
1128398000110	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1128398000111	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
1128398000112	dimer interface [polypeptide binding]; other site
1128398000113	active site
1128398000114	motif 1; other site
1128398000115	motif 2; other site
1128398000116	motif 3; other site
1128398000117	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1128398000118	HTH-like domain; Region: HTH_21; pfam13276
1128398000119	Integrase core domain; Region: rve; pfam00665
1128398000120	Integrase core domain; Region: rve_3; pfam13683
1128398000121	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
1128398000122	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1128398000123	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398000124	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1128398000125	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
1128398000126	nucleoside/Zn binding site; other site
1128398000127	dimer interface [polypeptide binding]; other site
1128398000128	catalytic motif [active]
1128398000129	Protein of unknown function (DUF2762); Region: DUF2762; pfam10960
1128398000130	Helix-turn-helix domain; Region: HTH_16; pfam12645
1128398000131	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1128398000132	S-layer homology domain; Region: SLH; pfam00395
1128398000133	S-layer homology domain; Region: SLH; pfam00395
1128398000134	S-layer homology domain; Region: SLH; pfam00395
1128398000135	B12 binding domain; Region: B12-binding; pfam02310
1128398000136	B12 binding site [chemical binding]; other site
1128398000137	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1128398000138	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1128398000139	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1128398000140	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1128398000141	metal binding site [ion binding]; metal-binding site
1128398000142	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
1128398000143	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
1128398000144	putative FMN binding site [chemical binding]; other site
1128398000145	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
1128398000146	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398000147	FeS/SAM binding site; other site
1128398000148	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
1128398000149	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398000150	FeS/SAM binding site; other site
1128398000151	putative bacteriocin precursor, CLOSPO_01332 family; Region: oc_CLOSPO_01332; TIGR04067
1128398000152	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398000153	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398000154	Walker A/P-loop; other site
1128398000155	ATP binding site [chemical binding]; other site
1128398000156	Q-loop/lid; other site
1128398000157	ABC transporter signature motif; other site
1128398000158	Walker B; other site
1128398000159	D-loop; other site
1128398000160	H-loop/switch region; other site
1128398000161	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1128398000162	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398000163	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
1128398000164	Walker A/P-loop; other site
1128398000165	ATP binding site [chemical binding]; other site
1128398000166	Q-loop/lid; other site
1128398000167	ABC transporter signature motif; other site
1128398000168	Walker B; other site
1128398000169	D-loop; other site
1128398000170	H-loop/switch region; other site
1128398000171	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
1128398000172	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398000173	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
1128398000174	Walker A/P-loop; other site
1128398000175	ATP binding site [chemical binding]; other site
1128398000176	Q-loop/lid; other site
1128398000177	ABC transporter signature motif; other site
1128398000178	Walker B; other site
1128398000179	D-loop; other site
1128398000180	H-loop/switch region; other site
1128398000181	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398000182	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398000183	active site
1128398000184	phosphorylation site [posttranslational modification]
1128398000185	intermolecular recognition site; other site
1128398000186	dimerization interface [polypeptide binding]; other site
1128398000187	LytTr DNA-binding domain; Region: LytTR; pfam04397
1128398000188	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1128398000189	Accessory gene regulator B; Region: AgrB; pfam04647
1128398000190	cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223
1128398000191	aspartate kinase; Reviewed; Region: PRK06635
1128398000192	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1128398000193	putative nucleotide binding site [chemical binding]; other site
1128398000194	putative catalytic residues [active]
1128398000195	putative Mg ion binding site [ion binding]; other site
1128398000196	putative aspartate binding site [chemical binding]; other site
1128398000197	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1128398000198	putative allosteric regulatory site; other site
1128398000199	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AK-LysC-DapG-like_2; cd04923
1128398000200	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
1128398000201	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
1128398000202	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
1128398000203	Threonine synthase [Amino acid transport and metabolism]; Region: ThrC; COG0498
1128398000204	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
1128398000205	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398000206	catalytic residue [active]
1128398000207	homoserine kinase; Provisional; Region: PRK01212
1128398000208	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1128398000209	hypothetical protein; Provisional; Region: PRK04435
1128398000210	Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed...; Region: HTH_Hin_like; cl17393
1128398000211	DNA-binding interface [nucleotide binding]; DNA binding site
1128398000212	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1128398000213	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
1128398000214	signal peptide peptidase SppA, 36K type; Region: SppA_dom; TIGR00706
1128398000215	tandem repeat interface [polypeptide binding]; other site
1128398000216	oligomer interface [polypeptide binding]; other site
1128398000217	active site residues [active]
1128398000218	RDD family; Region: RDD; pfam06271
1128398000219	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
1128398000220	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
1128398000221	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
1128398000222	lipoyl attachment site [posttranslational modification]; other site
1128398000223	Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain [Amino acid transport and metabolism]; Region: GcvP; COG0403
1128398000224	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1128398000225	tetramer interface [polypeptide binding]; other site
1128398000226	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398000227	catalytic residue [active]
1128398000228	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
1128398000229	tetramer interface [polypeptide binding]; other site
1128398000230	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398000231	catalytic residue [active]
1128398000232	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1128398000233	lipoyl synthase; Provisional; Region: PRK05481
1128398000234	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398000235	FeS/SAM binding site; other site
1128398000236	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398000237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398000238	active site
1128398000239	phosphorylation site [posttranslational modification]
1128398000240	intermolecular recognition site; other site
1128398000241	dimerization interface [polypeptide binding]; other site
1128398000242	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398000243	DNA binding site [nucleotide binding]
1128398000244	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398000245	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398000246	dimerization interface [polypeptide binding]; other site
1128398000247	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398000248	dimer interface [polypeptide binding]; other site
1128398000249	phosphorylation site [posttranslational modification]
1128398000250	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000251	ATP binding site [chemical binding]; other site
1128398000252	Mg2+ binding site [ion binding]; other site
1128398000253	G-X-G motif; other site
1128398000254	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1128398000255	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1128398000256	DNA binding residues [nucleotide binding]
1128398000257	drug binding residues [chemical binding]; other site
1128398000258	dimer interface [polypeptide binding]; other site
1128398000259	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1128398000260	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1128398000261	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1128398000262	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
1128398000263	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1128398000264	biotin synthase; Region: bioB; TIGR00433
1128398000265	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398000266	FeS/SAM binding site; other site
1128398000267	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
1128398000268	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
1128398000269	GIY-YIG motif/motif A; other site
1128398000270	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1128398000271	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1128398000272	catalytic residues [active]
1128398000273	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1128398000274	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1128398000275	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
1128398000276	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
1128398000277	active site
1128398000278	dimer interface [polypeptide binding]; other site
1128398000279	PAS domain S-box; Region: sensory_box; TIGR00229
1128398000280	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398000281	putative active site [active]
1128398000282	heme pocket [chemical binding]; other site
1128398000283	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398000284	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398000285	dimer interface [polypeptide binding]; other site
1128398000286	phosphorylation site [posttranslational modification]
1128398000287	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000288	ATP binding site [chemical binding]; other site
1128398000289	Mg2+ binding site [ion binding]; other site
1128398000290	G-X-G motif; other site
1128398000291	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398000292	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398000293	active site
1128398000294	phosphorylation site [posttranslational modification]
1128398000295	intermolecular recognition site; other site
1128398000296	dimerization interface [polypeptide binding]; other site
1128398000297	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; cl17549
1128398000298	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1128398000299	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1128398000300	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398000301	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1128398000302	dimer interface [polypeptide binding]; other site
1128398000303	conserved gate region; other site
1128398000304	putative PBP binding loops; other site
1128398000305	ABC-ATPase subunit interface; other site
1128398000306	DNA polymerase III, subunit gamma and tau; Region: dnaX_nterm; TIGR02397
1128398000307	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398000308	Walker A motif; other site
1128398000309	ATP binding site [chemical binding]; other site
1128398000310	Walker B motif; other site
1128398000311	arginine finger; other site
1128398000312	hypothetical protein; Validated; Region: PRK00153
1128398000313	recombination protein RecR; Reviewed; Region: recR; PRK00076
1128398000314	RecR protein; Region: RecR; pfam02132
1128398000315	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
1128398000316	putative active site [active]
1128398000317	putative metal-binding site [ion binding]; other site
1128398000318	tetramer interface [polypeptide binding]; other site
1128398000319	Rubrerythrin [Energy production and conversion]; Region: COG1592
1128398000320	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1128398000321	binuclear metal center [ion binding]; other site
1128398000322	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
1128398000323	iron binding site [ion binding]; other site
1128398000324	50S ribosomal protein L25/general stress protein Ctc; Reviewed; Region: PRK05618
1128398000325	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
1128398000326	5S rRNA interface [nucleotide binding]; other site
1128398000327	CTC domain interface [polypeptide binding]; other site
1128398000328	L16 interface [polypeptide binding]; other site
1128398000329	fumarate hydratase; Provisional; Region: PRK06246
1128398000330	Fumarase C-terminus; Region: Fumerase_C; cl00795
1128398000331	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
1128398000332	Malic enzyme, N-terminal domain; Region: malic; pfam00390
1128398000333	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
1128398000334	putative NAD(P) binding site [chemical binding]; other site
1128398000335	Inhibitor of sigma-G Gin; Region: Gin; pfam10764
1128398000336	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1128398000337	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398000338	catalytic residue [active]
1128398000339	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1128398000340	thymidylate kinase; Validated; Region: tmk; PRK00698
1128398000341	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
1128398000342	TMP-binding site; other site
1128398000343	ATP-binding site [chemical binding]; other site
1128398000344	Protein of unknown function (DUF970); Region: DUF970; cl17525
1128398000345	Protein of unknown function (DUF327); Region: DUF327; pfam03885
1128398000346	DNA polymerase III, delta' subunit; Region: holB; TIGR00678
1128398000347	DNA polymerase III subunit delta'; Validated; Region: PRK08485
1128398000348	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
1128398000349	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398000350	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398000351	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
1128398000352	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398000353	S-adenosylmethionine binding site [chemical binding]; other site
1128398000354	Predicted methyltransferases [General function prediction only]; Region: COG0313
1128398000355	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
1128398000356	putative SAM binding site [chemical binding]; other site
1128398000357	putative homodimer interface [polypeptide binding]; other site
1128398000358	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
1128398000359	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1128398000360	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
1128398000361	Uncharacterized membrane protein [Function unknown]; Region: SpmB; COG0700
1128398000362	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
1128398000363	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
1128398000364	active site
1128398000365	HIGH motif; other site
1128398000366	KMSKS motif; other site
1128398000367	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
1128398000368	anticodon binding site; other site
1128398000369	tRNA binding surface [nucleotide binding]; other site
1128398000370	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
1128398000371	dimer interface [polypeptide binding]; other site
1128398000372	putative tRNA-binding site [nucleotide binding]; other site
1128398000373	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
1128398000374	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
1128398000375	active site
1128398000376	Domain of unknown function (DUF348); Region: DUF348; pfam03990
1128398000377	G5 domain; Region: G5; pfam07501
1128398000378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
1128398000379	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
1128398000380	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
1128398000381	putative active site [active]
1128398000382	putative metal binding site [ion binding]; other site
1128398000383	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
1128398000384	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
1128398000385	Dimethyladenosine transferase (rRNA methylation) [Translation, ribosomal structure and biogenesis]; Region: KsgA; COG0030
1128398000386	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398000387	dimerization interface [polypeptide binding]; other site
1128398000388	putative DNA binding site [nucleotide binding]; other site
1128398000389	putative Zn2+ binding site [ion binding]; other site
1128398000390	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
1128398000391	catalytic residues [active]
1128398000392	hybrid cluster protein-associated redox disulfide domain; Region: prismane_assoc; TIGR03980
1128398000393	Membrane protein of unknown function; Region: DUF360; pfam04020
1128398000394	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1128398000395	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1128398000396	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1128398000397	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1128398000398	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1128398000399	ligand binding site [chemical binding]; other site
1128398000400	flexible hinge region; other site
1128398000401	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1128398000402	putative switch regulator; other site
1128398000403	non-specific DNA interactions [nucleotide binding]; other site
1128398000404	DNA binding site [nucleotide binding]
1128398000405	sequence specific DNA binding site [nucleotide binding]; other site
1128398000406	putative cAMP binding site [chemical binding]; other site
1128398000407	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1128398000408	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1128398000409	metal-binding site [ion binding]
1128398000410	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1128398000411	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1128398000412	metal-binding site [ion binding]
1128398000413	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398000414	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1128398000415	motif II; other site
1128398000416	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1128398000417	metal-binding site [ion binding]
1128398000418	Uncharacterized family 2; belongs to a superfamily containing transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156; Region: CsoR-like_DUF156_2; cd10159
1128398000419	putative homodimer interface [polypeptide binding]; other site
1128398000420	putative homotetramer interface [polypeptide binding]; other site
1128398000421	putative allosteric switch controlling residues; other site
1128398000422	putative metal binding site [ion binding]; other site
1128398000423	putative homodimer-homodimer interface [polypeptide binding]; other site
1128398000424	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1128398000425	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
1128398000426	Cl binding site [ion binding]; other site
1128398000427	oligomer interface [polypeptide binding]; other site
1128398000428	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1128398000429	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1128398000430	homodimer interface [polypeptide binding]; other site
1128398000431	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398000432	catalytic residue [active]
1128398000433	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1128398000434	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398000435	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000436	dimer interface [polypeptide binding]; other site
1128398000437	putative CheW interface [polypeptide binding]; other site
1128398000438	Heme NO binding; Region: HNOB; pfam07700
1128398000439	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398000440	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000441	dimer interface [polypeptide binding]; other site
1128398000442	putative CheW interface [polypeptide binding]; other site
1128398000443	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
1128398000444	S-adenosylmethionine decarboxylase; Region: AdoMet_dc; cl00687
1128398000445	spermidine synthase; Provisional; Region: PRK00811
1128398000446	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398000447	S-adenosylmethionine binding site [chemical binding]; other site
1128398000448	agmatinase; Region: agmatinase; TIGR01230
1128398000449	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
1128398000450	putative active site [active]
1128398000451	Mn binding site [ion binding]; other site
1128398000452	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1128398000453	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1128398000454	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
1128398000455	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
1128398000456	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398000457	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
1128398000458	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
1128398000459	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
1128398000460	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398000461	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398000462	Probable transposase; Region: OrfB_IS605; pfam01385
1128398000463	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398000464	Transcriptional regulators [Transcription]; Region: GntR; COG1802
1128398000465	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398000466	DNA-binding site [nucleotide binding]; DNA binding site
1128398000467	FCD domain; Region: FCD; pfam07729
1128398000468	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1128398000469	Spore germination protein; Region: Spore_permease; cl17796
1128398000470	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1128398000471	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1128398000472	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1128398000473	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1128398000474	germination protein, Ger(x)C family; Region: spore_ger_x_C; TIGR02887
1128398000475	Spore germination B3/ GerAC like, C-terminal; Region: Spore_GerAC; pfam05504
1128398000476	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; pfam09551
1128398000477	spore cortex-lytic enzyme; Region: spore_SleB; TIGR02869
1128398000478	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1128398000479	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1128398000480	germination protein YpeB; Region: spore_YpeB; TIGR02889
1128398000481	glutamate racemase; Provisional; Region: PRK00865
1128398000482	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
1128398000483	Monoamine oxidase [Amino acid transport and metabolism]; Region: COG1231
1128398000484	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1128398000485	Putative silver efflux pump [Inorganic ion transport and metabolism]; Region: COG3696
1128398000486	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1128398000487	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1128398000488	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1128398000489	Immunoglobulin-like fold, Plexins, Transcription factors (IPT). IPTs are also known as Transcription factor ImmunoGlobin (TIG) domains. They are present in intracellular transcription factors, cell surface receptors (such as plexins and scatter factor...; Region: IPT; cd00102
1128398000490	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
1128398000491	Interdomain contacts; other site
1128398000492	Cytokine receptor motif; other site
1128398000493	S-layer homology domain; Region: SLH; pfam00395
1128398000494	S-layer homology domain; Region: SLH; pfam00395
1128398000495	S-layer homology domain; Region: SLH; pfam00395
1128398000496	S-layer homology domain; Region: SLH; pfam00395
1128398000497	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1128398000498	C-terminal peptidase (prc); Region: prc; TIGR00225
1128398000499	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1128398000500	protein binding site [polypeptide binding]; other site
1128398000501	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1128398000502	Catalytic dyad [active]
1128398000503	S-layer homology domain; Region: SLH; pfam00395
1128398000504	S-layer homology domain; Region: SLH; pfam00395
1128398000505	Catalytic domain of phosphoinositide-specific phospholipase C-like phosphodiesterases superfamily; Region: PI-PLCc_GDPD_SF; cl14615
1128398000506	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
1128398000507	active site
1128398000508	catalytic site [active]
1128398000509	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4868
1128398000510	hypothetical protein; Provisional; Region: PRK13663
1128398000511	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398000512	S-layer homology domain; Region: SLH; pfam00395
1128398000513	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398000514	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398000515	active site
1128398000516	phosphorylation site [posttranslational modification]
1128398000517	intermolecular recognition site; other site
1128398000518	dimerization interface [polypeptide binding]; other site
1128398000519	fructose-bisphosphate aldolase; Provisional; Region: PRK09197
1128398000520	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
1128398000521	intersubunit interface [polypeptide binding]; other site
1128398000522	active site
1128398000523	zinc binding site [ion binding]; other site
1128398000524	Na+ binding site [ion binding]; other site
1128398000525	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
1128398000526	active site
1128398000527	intersubunit interactions; other site
1128398000528	catalytic residue [active]
1128398000529	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
1128398000530	Bacterial fructose-1,6-bisphosphatase, glpX-encoded; Region: FBPase_glpX; pfam03320
1128398000531	putative active site [active]
1128398000532	transcription termination factor Rho; Provisional; Region: rho; PRK09376
1128398000533	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
1128398000534	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
1128398000535	RNA binding site [nucleotide binding]; other site
1128398000536	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
1128398000537	multimer interface [polypeptide binding]; other site
1128398000538	Walker A motif; other site
1128398000539	ATP binding site [chemical binding]; other site
1128398000540	Walker B motif; other site
1128398000541	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
1128398000542	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
1128398000543	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
1128398000544	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398000545	S-adenosylmethionine binding site [chemical binding]; other site
1128398000546	Chromate transporter; Region: Chromate_transp; pfam02417
1128398000547	Chromate transporter; Region: Chromate_transp; pfam02417
1128398000548	peptide chain release factor 1; Validated; Region: prfA; PRK00591
1128398000549	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1128398000550	RF-1 domain; Region: RF-1; pfam00472
1128398000551	Predicted divalent heavy-metal cations transporter [Inorganic ion transport and metabolism]; Region: COG0428
1128398000552	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
1128398000553	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
1128398000554	Low molecular weight phosphatase family; Region: LMWPc; cd00115
1128398000555	Low molecular weight phosphotyrosine protein phosphatase; Region: LMWPc; pfam01451
1128398000556	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
1128398000557	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398000558	active site
1128398000559	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
1128398000560	catalytic motif [active]
1128398000561	Zn binding site [ion binding]; other site
1128398000562	UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase [Cell envelope biogenesis, outer membrane]; Region: Rfe; COG0472
1128398000563	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
1128398000564	Mg++ binding site [ion binding]; other site
1128398000565	putative catalytic motif [active]
1128398000566	substrate binding site [chemical binding]; other site
1128398000567	UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane]; Region: WecB; COG0381
1128398000568	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
1128398000569	active site
1128398000570	homodimer interface [polypeptide binding]; other site
1128398000571	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
1128398000572	ATP synthase I chain; Region: ATP_synt_I; cl09170
1128398000573	F0F1-type ATP synthase, subunit a [Energy production and conversion]; Region: AtpB; COG0356
1128398000574	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
1128398000575	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
1128398000576	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
1128398000577	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
1128398000578	F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) [Energy production and conversion]; Region: AtpH; cl17210
1128398000579	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
1128398000580	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1128398000581	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
1128398000582	beta subunit interaction interface [polypeptide binding]; other site
1128398000583	Walker A motif; other site
1128398000584	ATP binding site [chemical binding]; other site
1128398000585	Walker B motif; other site
1128398000586	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1128398000587	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
1128398000588	core domain interface [polypeptide binding]; other site
1128398000589	delta subunit interface [polypeptide binding]; other site
1128398000590	epsilon subunit interface [polypeptide binding]; other site
1128398000591	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
1128398000592	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1128398000593	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
1128398000594	alpha subunit interaction interface [polypeptide binding]; other site
1128398000595	Walker A motif; other site
1128398000596	ATP binding site [chemical binding]; other site
1128398000597	Walker B motif; other site
1128398000598	inhibitor binding site; inhibition site
1128398000599	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
1128398000600	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
1128398000601	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
1128398000602	gamma subunit interface [polypeptide binding]; other site
1128398000603	epsilon subunit interface [polypeptide binding]; other site
1128398000604	LBP interface [polypeptide binding]; other site
1128398000605	Protein of unknown function (DUF1779); Region: DUF1779; pfam08680
1128398000606	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1128398000607	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1128398000608	hinge; other site
1128398000609	active site
1128398000610	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1128398000611	Stage II sporulation protein; Region: SpoIID; pfam08486
1128398000612	Peptidase family M23; Region: Peptidase_M23; pfam01551
1128398000613	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1128398000614	Stage III sporulation protein D; Region: SpoIIID; pfam12116
1128398000615	rod shape-determining protein Mbl; Provisional; Region: PRK13928
1128398000616	MreB and similar proteins; Region: MreB_like; cd10225
1128398000617	nucleotide binding site [chemical binding]; other site
1128398000618	Mg binding site [ion binding]; other site
1128398000619	putative protofilament interaction site [polypeptide binding]; other site
1128398000620	RodZ interaction site [polypeptide binding]; other site
1128398000621	Flagellar hook protein FlgE [Cell motility and secretion]; Region: FlgE; COG1749
1128398000622	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1128398000623	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398000624	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
1128398000625	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1128398000626	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398000627	Rod binding protein; Region: Rod-binding; cl01626
1128398000628	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
1128398000629	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1128398000630	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
1128398000631	dimer interface [polypeptide binding]; other site
1128398000632	active site
1128398000633	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cl15837
1128398000634	YibE/F-like protein; Region: YibE_F; pfam07907
1128398000635	S-layer homology domain; Region: SLH; pfam00395
1128398000636	S-layer homology domain; Region: SLH; pfam00395
1128398000637	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1128398000638	Metal-binding active site; metal-binding site
1128398000639	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
1128398000640	AP (apurinic/apyrimidinic) site pocket; other site
1128398000641	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
1128398000642	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
1128398000643	active site
1128398000644	substrate binding site [chemical binding]; other site
1128398000645	metal binding site [ion binding]; metal-binding site
1128398000646	Predicted periplasmic protein (DUF2233); Region: DUF2233; pfam09992
1128398000647	cell division suppressor protein YneA; Provisional; Region: PRK14125
1128398000648	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cl00257
1128398000649	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
1128398000650	S-adenosylmethionine synthetase; Validated; Region: PRK05250
1128398000651	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
1128398000652	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
1128398000653	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1128398000654	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398000655	DNA binding residues [nucleotide binding]
1128398000656	Protein of unknown function (DUF1659); Region: DUF1659; pfam07872
1128398000657	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
1128398000658	YvrJ protein family; Region: YvrJ; pfam12841
1128398000659	Accessory gene regulator B; Region: AgrB; cl01873
1128398000660	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1128398000661	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1128398000662	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
1128398000663	homodimer interface [polypeptide binding]; other site
1128398000664	NADP binding site [chemical binding]; other site
1128398000665	substrate binding site [chemical binding]; other site
1128398000666	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
1128398000667	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1128398000668	DNA binding site [nucleotide binding]
1128398000669	AAA domain; Region: AAA_30; pfam13604
1128398000670	Family description; Region: UvrD_C_2; pfam13538
1128398000671	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
1128398000672	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398000673	active site
1128398000674	flagellar operon protein TIGR03826; Region: YvyF
1128398000675	flagellar biosynthesis anti-sigma factor FlgM; Region: FlgM_jcvi; TIGR03824
1128398000676	FlgN protein; Region: FlgN; pfam05130
1128398000677	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
1128398000678	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398000679	Flagellar hook-associated protein [Cell motility and secretion]; Region: FlgK; COG1256
1128398000680	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398000681	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1128398000682	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1128398000683	flagellar assembly protein FliW; Provisional; Region: PRK13285
1128398000684	carbon storage regulator; Provisional; Region: PRK01712
1128398000685	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
1128398000686	flagellin; Provisional; Region: PRK12804
1128398000687	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
1128398000688	Putative motility protein; Region: YjfB_motility; pfam14070
1128398000689	flagellar operon protein TIGR03826; Region: YvyF
1128398000690	flagellar operon protein TIGR03826; Region: YvyF
1128398000691	FOG: CBS domain [General function prediction only]; Region: COG0517
1128398000692	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1128398000693	FlaG protein; Region: FlaG; pfam03646
1128398000694	flagellar capping protein; Validated; Region: fliD; PRK07737
1128398000695	Flagellar hook-associated protein 2 C-terminus; Region: FliD_N; pfam02465
1128398000696	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
1128398000697	Flagellar protein FliS; Region: FliS; cl00654
1128398000698	FlgN protein; Region: FlgN; pfam05130
1128398000699	phosphodiesterase; Provisional; Region: PRK12704
1128398000700	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
1128398000701	30S subunit binding site; other site
1128398000702	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
1128398000703	DEAD/DEAH box helicase; Region: DEAD; pfam00270
1128398000704	ATP binding site [chemical binding]; other site
1128398000705	putative Mg++ binding site [ion binding]; other site
1128398000706	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
1128398000707	SEC-C motif; Region: SEC-C; pfam02810
1128398000708	peptide chain release factor 2; Provisional; Region: PRK05589
1128398000709	This domain is found in peptide chain release factors; Region: PCRF; smart00937
1128398000710	RF-1 domain; Region: RF-1; pfam00472
1128398000711	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
1128398000712	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
1128398000713	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
1128398000714	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
1128398000715	RNA binding site [nucleotide binding]; other site
1128398000716	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398000717	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398000718	dimer interface [polypeptide binding]; other site
1128398000719	phosphorylation site [posttranslational modification]
1128398000720	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000721	ATP binding site [chemical binding]; other site
1128398000722	Mg2+ binding site [ion binding]; other site
1128398000723	G-X-G motif; other site
1128398000724	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
1128398000725	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398000726	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
1128398000727	active site
1128398000728	Predicted membrane protein [Function unknown]; Region: COG3601
1128398000729	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1128398000730	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
1128398000731	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1128398000732	Glycoprotease family; Region: Peptidase_M22; pfam00814
1128398000733	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
1128398000734	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398000735	Coenzyme A binding pocket [chemical binding]; other site
1128398000736	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
1128398000737	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1128398000738	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1128398000739	HlyD family secretion protein; Region: HlyD_3; pfam13437
1128398000740	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398000741	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398000742	Walker A/P-loop; other site
1128398000743	ATP binding site [chemical binding]; other site
1128398000744	Q-loop/lid; other site
1128398000745	ABC transporter signature motif; other site
1128398000746	Walker B; other site
1128398000747	D-loop; other site
1128398000748	H-loop/switch region; other site
1128398000749	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398000750	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1128398000751	FtsX-like permease family; Region: FtsX; pfam02687
1128398000752	UGMP family protein; Validated; Region: PRK09604
1128398000753	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
1128398000754	Carbamoyltransferase; Region: CmcH_NodU; pfam02543
1128398000755	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1128398000756	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398000757	Walker A/P-loop; other site
1128398000758	ATP binding site [chemical binding]; other site
1128398000759	Q-loop/lid; other site
1128398000760	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398000761	ABC transporter signature motif; other site
1128398000762	Walker B; other site
1128398000763	D-loop; other site
1128398000764	ABC transporter; Region: ABC_tran_2; pfam12848
1128398000765	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398000766	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
1128398000767	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
1128398000768	CoA binding domain; Region: CoA_binding; smart00881
1128398000769	Cache domain; Region: Cache_1; pfam02743
1128398000770	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398000771	dimerization interface [polypeptide binding]; other site
1128398000772	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398000773	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000774	dimer interface [polypeptide binding]; other site
1128398000775	putative CheW interface [polypeptide binding]; other site
1128398000776	Cache domain; Region: Cache_1; pfam02743
1128398000777	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398000778	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398000779	dimerization interface [polypeptide binding]; other site
1128398000780	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000781	dimer interface [polypeptide binding]; other site
1128398000782	putative CheW interface [polypeptide binding]; other site
1128398000783	Cache domain; Region: Cache_1; pfam02743
1128398000784	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398000785	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398000786	dimerization interface [polypeptide binding]; other site
1128398000787	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000788	dimer interface [polypeptide binding]; other site
1128398000789	putative CheW interface [polypeptide binding]; other site
1128398000790	Asp23 family; Region: Asp23; pfam03780
1128398000791	glutamate dehydrogenase; Provisional; Region: PRK09414
1128398000792	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
1128398000793	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
1128398000794	NAD(P) binding site [chemical binding]; other site
1128398000795	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
1128398000796	8-oxoguanine DNA-glycosylase (ogg); Region: ogg; TIGR00588
1128398000797	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1128398000798	minor groove reading motif; other site
1128398000799	helix-hairpin-helix signature motif; other site
1128398000800	substrate binding pocket [chemical binding]; other site
1128398000801	active site
1128398000802	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398000803	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398000804	active site
1128398000805	phosphorylation site [posttranslational modification]
1128398000806	intermolecular recognition site; other site
1128398000807	dimerization interface [polypeptide binding]; other site
1128398000808	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398000809	DNA binding site [nucleotide binding]
1128398000810	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398000811	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398000812	ATP binding site [chemical binding]; other site
1128398000813	Mg2+ binding site [ion binding]; other site
1128398000814	G-X-G motif; other site
1128398000815	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398000816	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398000817	Walker A/P-loop; other site
1128398000818	ATP binding site [chemical binding]; other site
1128398000819	Q-loop/lid; other site
1128398000820	ABC transporter signature motif; other site
1128398000821	Walker B; other site
1128398000822	D-loop; other site
1128398000823	H-loop/switch region; other site
1128398000824	FtsX-like permease family; Region: FtsX; pfam02687
1128398000825	Histidine Utilizing Protein, the hut operon positive regulatory protein; Region: HutP; cd11640
1128398000826	hexamer interface [polypeptide binding]; other site
1128398000827	RNA binding site [nucleotide binding]; other site
1128398000828	Histidine-zinc binding site [chemical binding]; other site
1128398000829	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
1128398000830	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1128398000831	zinc binding site [ion binding]; other site
1128398000832	putative ligand binding site [chemical binding]; other site
1128398000833	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1128398000834	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
1128398000835	TM-ABC transporter signature motif; other site
1128398000836	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
1128398000837	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398000838	Walker A/P-loop; other site
1128398000839	ATP binding site [chemical binding]; other site
1128398000840	Q-loop/lid; other site
1128398000841	ABC transporter signature motif; other site
1128398000842	Walker B; other site
1128398000843	D-loop; other site
1128398000844	H-loop/switch region; other site
1128398000845	Protein of unknown function (DUF554); Region: DUF554; pfam04474
1128398000846	Collagen binding domain; Region: Collagen_bind; pfam05737
1128398000847	Predicted outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG4932
1128398000848	Collagen binding domain; Region: Collagen_bind; pfam05737
1128398000849	Collagen binding domain; Region: Collagen_bind; pfam05737
1128398000850	Collagen binding domain; Region: Collagen_bind; pfam05737
1128398000851	Collagen binding domain; Region: Collagen_bind; pfam05737
1128398000852	Cna protein B-type domain; Region: Cna_B; pfam05738
1128398000853	Cna protein B-type domain; Region: Cna_B; pfam05738
1128398000854	Cna protein B-type domain; Region: Cna_B; pfam05738
1128398000855	Cna protein B-type domain; Region: Cna_B; pfam05738
1128398000856	Cna protein B-type domain; Region: Cna_B; pfam05738
1128398000857	Sortase D (SrtD) is a membrane transpeptidase found in gram-positive bacteria that anchors surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the surface protein substrate is cleaved...; Region: Sortase_D_5; cd06166
1128398000858	active site
1128398000859	catalytic site [active]
1128398000860	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
1128398000861	oligomerisation interface [polypeptide binding]; other site
1128398000862	mobile loop; other site
1128398000863	roof hairpin; other site
1128398000864	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
1128398000865	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
1128398000866	ring oligomerisation interface [polypeptide binding]; other site
1128398000867	ATP/Mg binding site [chemical binding]; other site
1128398000868	stacking interactions; other site
1128398000869	hinge regions; other site
1128398000870	GMP synthase, PP-ATPase domain/subunit [Nucleotide transport and metabolism]; Region: GuaA; COG0519
1128398000871	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
1128398000872	ATP Binding subdomain [chemical binding]; other site
1128398000873	Ligand Binding sites [chemical binding]; other site
1128398000874	Dimerization subdomain; other site
1128398000875	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
1128398000876	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
1128398000877	purine monophosphate binding site [chemical binding]; other site
1128398000878	dimer interface [polypeptide binding]; other site
1128398000879	putative catalytic residues [active]
1128398000880	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
1128398000881	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; cl03362
1128398000882	Cache domain; Region: Cache_1; pfam02743
1128398000883	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398000884	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398000885	dimerization interface [polypeptide binding]; other site
1128398000886	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398000887	dimer interface [polypeptide binding]; other site
1128398000888	putative CheW interface [polypeptide binding]; other site
1128398000889	Formiminotransferase domain, N-terminal subdomain; Region: FTCD_N; pfam07837
1128398000890	Glutamate formiminotransferase [Amino acid transport and metabolism]; Region: COG3643
1128398000891	Formiminotransferase domain; Region: FTCD; pfam02971
1128398000892	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
1128398000893	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
1128398000894	Potassium binding sites [ion binding]; other site
1128398000895	Cesium cation binding sites [ion binding]; other site
1128398000896	Trp repressor protein; Region: Trp_repressor; cl17266
1128398000897	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1128398000898	active site
1128398000899	ATP binding site [chemical binding]; other site
1128398000900	type I secretion outer membrane protein, TolC family; Region: type_I_sec_TolC; TIGR01844
1128398000901	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1128398000902	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1128398000903	HlyD family secretion protein; Region: HlyD_3; pfam13437
1128398000904	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1128398000905	Protein export membrane protein; Region: SecD_SecF; cl14618
1128398000906	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398000907	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398000908	60Kd inner membrane protein; Region: 60KD_IMP; pfam02096
1128398000909	UvrD/REP helicase N-terminal domain; Region: UvrD-helicase; pfam00580
1128398000910	Part of AAA domain; Region: AAA_19; pfam13245
1128398000911	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cd00081
1128398000912	protein-splicing catalytic site; other site
1128398000913	thioester formation/cholesterol transfer; other site
1128398000914	Hedgehog/Intein domain, found in Hedgehog proteins as well as proteins which contain inteins and undergo protein splicing (e.g. DnaB, RIR1-2, GyrA and Pol). In protein splicing an intervening polypeptide sequence - the intein - is excised from a protein; Region: Hint; cl17442
1128398000915	protein-splicing catalytic site; other site
1128398000916	UvrD-like helicase C-terminal domain; Region: UvrD_C; pfam13361
1128398000917	Family description; Region: UvrD_C_2; pfam13538
1128398000918	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
1128398000919	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
1128398000920	nucleotide binding pocket [chemical binding]; other site
1128398000921	K-X-D-G motif; other site
1128398000922	catalytic site [active]
1128398000923	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
1128398000924	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1128398000925	DNA binding site [nucleotide binding]
1128398000926	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1128398000927	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
1128398000928	Dimer interface [polypeptide binding]; other site
1128398000929	BRCT sequence motif; other site
1128398000930	aspartyl/glutamyl-tRNA amidotransferase subunit C; Reviewed; Region: gatC; PRK00034
1128398000931	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
1128398000932	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
1128398000933	aspartyl/glutamyl-tRNA amidotransferase subunit B; Validated; Region: gatB; PRK05477
1128398000934	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
1128398000935	GatB domain; Region: GatB_Yqey; smart00845
1128398000936	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1128398000937	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398000938	dimer interface [polypeptide binding]; other site
1128398000939	conserved gate region; other site
1128398000940	putative PBP binding loops; other site
1128398000941	ABC-ATPase subunit interface; other site
1128398000942	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
1128398000943	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
1128398000944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398000945	dimer interface [polypeptide binding]; other site
1128398000946	conserved gate region; other site
1128398000947	putative PBP binding loops; other site
1128398000948	ABC-ATPase subunit interface; other site
1128398000949	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1128398000950	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1128398000951	Walker A/P-loop; other site
1128398000952	ATP binding site [chemical binding]; other site
1128398000953	Q-loop/lid; other site
1128398000954	ABC transporter signature motif; other site
1128398000955	Walker B; other site
1128398000956	D-loop; other site
1128398000957	H-loop/switch region; other site
1128398000958	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1128398000959	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
1128398000960	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1128398000961	Walker A/P-loop; other site
1128398000962	ATP binding site [chemical binding]; other site
1128398000963	Q-loop/lid; other site
1128398000964	ABC transporter signature motif; other site
1128398000965	Walker B; other site
1128398000966	D-loop; other site
1128398000967	H-loop/switch region; other site
1128398000968	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1128398000969	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
1128398000970	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
1128398000971	peptide binding site [polypeptide binding]; other site
1128398000972	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398000973	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398000974	S-adenosylmethionine binding site [chemical binding]; other site
1128398000975	Hydrogenase maturation factor [Posttranslational modification, protein turnover, chaperones]; Region: HypE; COG0309
1128398000976	AIR synthase (PurM) related protein, subgroup 1 of unknown function. The family of PurM related proteins includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM synthase and Selenophosphate synthetase (SelD). They all contain two...; Region: PurM-like1; cd06061
1128398000977	dimerization interface [polypeptide binding]; other site
1128398000978	putative ATP binding site [chemical binding]; other site
1128398000979	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398000980	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398000981	AMIN domain; Region: AMIN; pfam11741
1128398000982	AMIN domain; Region: AMIN; pfam11741
1128398000983	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398000984	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398000985	active site
1128398000986	metal binding site [ion binding]; metal-binding site
1128398000987	Sporulation and spore germination; Region: Germane; pfam10646
1128398000988	Sporulation and spore germination; Region: Germane; pfam10646
1128398000989	ribonuclease PH; Reviewed; Region: rph; PRK00173
1128398000990	Ribonuclease PH; Region: RNase_PH_bact; cd11362
1128398000991	hexamer interface [polypeptide binding]; other site
1128398000992	active site
1128398000993	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
1128398000994	active site
1128398000995	dimerization interface [polypeptide binding]; other site
1128398000996	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1128398000997	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1128398000998	active site
1128398000999	metal binding site [ion binding]; metal-binding site
1128398001000	homotetramer interface [polypeptide binding]; other site
1128398001001	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1128398001002	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1128398001003	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398001004	DNA-binding site [nucleotide binding]; DNA binding site
1128398001005	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398001006	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398001007	homodimer interface [polypeptide binding]; other site
1128398001008	catalytic residue [active]
1128398001009	methylated-DNA--protein-cysteine methyltransferase; Provisional; Region: PRK00901
1128398001010	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
1128398001011	DNA binding site [nucleotide binding]
1128398001012	active site
1128398001013	DNA alkylation repair enzyme; Region: DNA_alkylation; pfam08713
1128398001014	A new structural DNA glycosylase; Region: AlkD_like; cd06561
1128398001015	active site
1128398001016	Spo0E like sporulation regulatory protein; Region: SpoOE-like; pfam09388
1128398001017	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398001018	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
1128398001019	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1128398001020	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1128398001021	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1128398001022	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
1128398001023	EamA-like transporter family; Region: EamA; pfam00892
1128398001024	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1128398001025	EamA-like transporter family; Region: EamA; pfam00892
1128398001026	trigger factor; Provisional; Region: tig; PRK01490
1128398001027	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
1128398001028	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
1128398001029	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
1128398001030	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1128398001031	oligomer interface [polypeptide binding]; other site
1128398001032	active site residues [active]
1128398001033	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
1128398001034	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
1128398001035	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398001036	Walker A motif; other site
1128398001037	ATP binding site [chemical binding]; other site
1128398001038	Walker B motif; other site
1128398001039	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1128398001040	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398001041	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398001042	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398001043	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398001044	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1128398001045	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1128398001046	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398001047	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1128398001048	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1128398001049	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
1128398001050	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
1128398001051	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
1128398001052	active site
1128398001053	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001054	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1128398001055	intersubunit interface [polypeptide binding]; other site
1128398001056	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1128398001057	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1128398001058	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1128398001059	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001060	ABC-ATPase subunit  interface; other site
1128398001061	dimer interface [polypeptide binding]; other site
1128398001062	putative PBP binding regions; other site
1128398001063	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1128398001064	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001065	ABC-ATPase subunit  interface; other site
1128398001066	dimer interface [polypeptide binding]; other site
1128398001067	putative PBP binding regions; other site
1128398001068	FeoA domain; Region: FeoA; pfam04023
1128398001069	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1128398001070	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1128398001071	G1 box; other site
1128398001072	GTP/Mg2+ binding site [chemical binding]; other site
1128398001073	Switch I region; other site
1128398001074	G2 box; other site
1128398001075	G3 box; other site
1128398001076	Switch II region; other site
1128398001077	G4 box; other site
1128398001078	G5 box; other site
1128398001079	Nucleoside recognition; Region: Gate; pfam07670
1128398001080	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
1128398001081	Nucleoside recognition; Region: Gate; pfam07670
1128398001082	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398001083	S-adenosylmethionine binding site [chemical binding]; other site
1128398001084	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
1128398001085	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1128398001086	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1128398001087	ligand binding site [chemical binding]; other site
1128398001088	flexible hinge region; other site
1128398001089	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398001090	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1128398001091	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398001092	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; pfam09989
1128398001093	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1128398001094	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1128398001095	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
1128398001096	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398001097	Walker A/P-loop; other site
1128398001098	ATP binding site [chemical binding]; other site
1128398001099	Q-loop/lid; other site
1128398001100	ABC transporter signature motif; other site
1128398001101	Walker B; other site
1128398001102	D-loop; other site
1128398001103	H-loop/switch region; other site
1128398001104	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1128398001105	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1128398001106	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398001107	dimer interface [polypeptide binding]; other site
1128398001108	conserved gate region; other site
1128398001109	putative PBP binding loops; other site
1128398001110	ABC-ATPase subunit interface; other site
1128398001111	Cupin domain; Region: Cupin_2; pfam07883
1128398001112	Cupin domain; Region: Cupin_2; cl17218
1128398001113	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1128398001114	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1128398001115	ligand binding site [chemical binding]; other site
1128398001116	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
1128398001117	putative switch regulator; other site
1128398001118	non-specific DNA interactions [nucleotide binding]; other site
1128398001119	DNA binding site [nucleotide binding]
1128398001120	sequence specific DNA binding site [nucleotide binding]; other site
1128398001121	putative cAMP binding site [chemical binding]; other site
1128398001122	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001123	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001124	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001125	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398001126	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
1128398001127	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398001128	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001129	intersubunit interface [polypeptide binding]; other site
1128398001130	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398001131	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001132	ABC-ATPase subunit  interface; other site
1128398001133	dimer interface [polypeptide binding]; other site
1128398001134	putative PBP binding regions; other site
1128398001135	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398001136	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398001137	Walker A/P-loop; other site
1128398001138	ATP binding site [chemical binding]; other site
1128398001139	Q-loop/lid; other site
1128398001140	ABC transporter signature motif; other site
1128398001141	Walker B; other site
1128398001142	D-loop; other site
1128398001143	H-loop/switch region; other site
1128398001144	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398001145	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cd00316
1128398001146	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398001147	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cd00316
1128398001148	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1128398001149	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1128398001150	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398001151	RNA binding surface [nucleotide binding]; other site
1128398001152	Predicted transcriptional regulators [Transcription]; Region: COG1733
1128398001153	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1128398001154	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1128398001155	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1128398001156	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
1128398001157	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
1128398001158	RibD C-terminal domain; Region: RibD_C; cl17279
1128398001159	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001160	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001161	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1128398001162	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398001163	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1128398001164	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
1128398001165	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398001166	ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Region: PQQ_ABC_ATP; TIGR03864
1128398001167	Walker A/P-loop; other site
1128398001168	ATP binding site [chemical binding]; other site
1128398001169	Q-loop/lid; other site
1128398001170	ABC transporter signature motif; other site
1128398001171	Walker B; other site
1128398001172	D-loop; other site
1128398001173	H-loop/switch region; other site
1128398001174	First Helix-Turn-Helix DNA binding domain of the regulatory protein TioE; Region: HTH_TioE_rpt1; cd04772
1128398001175	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1128398001176	DNA binding residues [nucleotide binding]
1128398001177	putative dimer interface [polypeptide binding]; other site
1128398001178	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
1128398001179	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1128398001180	DNA binding residues [nucleotide binding]
1128398001181	dimer interface [polypeptide binding]; other site
1128398001182	HAMP domain; Region: HAMP; pfam00672
1128398001183	dimerization interface [polypeptide binding]; other site
1128398001184	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398001185	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398001186	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398001187	dimer interface [polypeptide binding]; other site
1128398001188	putative CheW interface [polypeptide binding]; other site
1128398001189	3'-5' exoribonuclease YhaM; Provisional; Region: PRK13480
1128398001190	YhaM_OBF_like: A subfamily of OB folds similar to that found in Bacillus subtilis YhaM and Staphylococcus aureus cmp-binding factor-1 (SaCBF1). Both these proteins are 3'-to-5'exoribonucleases. YhaM requires Mn2+ or Co2+ for activity and is...; Region: YhaM_OBF_like; cd04492
1128398001191	generic binding surface II; other site
1128398001192	generic binding surface I; other site
1128398001193	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398001194	Zn2+ binding site [ion binding]; other site
1128398001195	Mg2+ binding site [ion binding]; other site
1128398001196	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001197	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001198	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001199	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1128398001200	intersubunit interface [polypeptide binding]; other site
1128398001201	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001202	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1128398001203	intersubunit interface [polypeptide binding]; other site
1128398001204	Family description; Region: VCBS; pfam13517
1128398001205	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001206	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001207	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001208	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398001209	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001210	intersubunit interface [polypeptide binding]; other site
1128398001211	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001212	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001213	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398001214	Periplasmic binding protein FeuA.  These proteins have predicted to function as initial receptors in ABC transport of metal ions in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: FeuA; cd01138
1128398001215	putative ligand binding residues [chemical binding]; other site
1128398001216	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398001217	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001218	intersubunit interface [polypeptide binding]; other site
1128398001219	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398001220	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398001221	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1128398001222	Walker A/P-loop; other site
1128398001223	ATP binding site [chemical binding]; other site
1128398001224	Q-loop/lid; other site
1128398001225	ABC transporter signature motif; other site
1128398001226	Walker B; other site
1128398001227	D-loop; other site
1128398001228	H-loop/switch region; other site
1128398001229	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
1128398001230	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001231	ABC-ATPase subunit  interface; other site
1128398001232	dimer interface [polypeptide binding]; other site
1128398001233	putative PBP binding regions; other site
1128398001234	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398001235	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001236	ABC-ATPase subunit  interface; other site
1128398001237	dimer interface [polypeptide binding]; other site
1128398001238	putative PBP binding regions; other site
1128398001239	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398001240	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398001241	Walker A/P-loop; other site
1128398001242	ATP binding site [chemical binding]; other site
1128398001243	Q-loop/lid; other site
1128398001244	ABC transporter signature motif; other site
1128398001245	Walker B; other site
1128398001246	D-loop; other site
1128398001247	H-loop/switch region; other site
1128398001248	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1128398001249	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001250	intersubunit interface [polypeptide binding]; other site
1128398001251	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001252	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001253	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001254	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1128398001255	intersubunit interface [polypeptide binding]; other site
1128398001256	Flavodoxin domain; Region: Flavodoxin_3; pfam12641
1128398001257	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
1128398001258	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398001259	DNA-binding site [nucleotide binding]; DNA binding site
1128398001260	UTRA domain; Region: UTRA; pfam07702
1128398001261	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398001262	Predicted membrane protein [Function unknown]; Region: COG2364
1128398001263	hydroxydechloroatrazine ethylaminohydrolase; Reviewed; Region: PRK08203
1128398001264	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1128398001265	active site
1128398001266	putative substrate binding pocket [chemical binding]; other site
1128398001267	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398001268	ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones]; Region: ATM1; COG5265
1128398001269	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398001270	Walker A/P-loop; other site
1128398001271	ATP binding site [chemical binding]; other site
1128398001272	Q-loop/lid; other site
1128398001273	ABC transporter signature motif; other site
1128398001274	Walker B; other site
1128398001275	D-loop; other site
1128398001276	H-loop/switch region; other site
1128398001277	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398001278	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398001279	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398001280	Walker A/P-loop; other site
1128398001281	ATP binding site [chemical binding]; other site
1128398001282	Q-loop/lid; other site
1128398001283	ABC transporter signature motif; other site
1128398001284	Walker B; other site
1128398001285	D-loop; other site
1128398001286	H-loop/switch region; other site
1128398001287	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1128398001288	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1128398001289	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1128398001290	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1128398001291	homodimer interface [polypeptide binding]; other site
1128398001292	substrate-cofactor binding pocket; other site
1128398001293	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398001294	catalytic residue [active]
1128398001295	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398001296	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398001297	Zn2+ binding site [ion binding]; other site
1128398001298	Mg2+ binding site [ion binding]; other site
1128398001299	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1128398001300	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1128398001301	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
1128398001302	MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149
1128398001303	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
1128398001304	P loop nucleotide binding; other site
1128398001305	switch II; other site
1128398001306	MinD superfamily P-loop ATPase containing an inserted ferredoxin domain [Energy production and conversion]; Region: COG1149
1128398001307	This protein family's function is unkown. It contains nucleotide binding site. It uses NTP as energy source to transfer electron or ion; Region: Fer4_NifH_child; cd03110
1128398001308	P loop nucleotide binding; other site
1128398001309	switch II; other site
1128398001310	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
1128398001311	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
1128398001312	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
1128398001313	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1128398001314	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398001315	DNA binding residues [nucleotide binding]
1128398001316	Uncharacterized conserved protein [Function unknown]; Region: COG2014
1128398001317	Domain of unknown function (DUF4213); Region: DUF4213; pfam13938
1128398001318	Domain of unknown function (DUF364); Region: DUF364; pfam04016
1128398001319	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398001320	Coenzyme A binding pocket [chemical binding]; other site
1128398001321	YoaP-like; Region: YoaP; pfam14268
1128398001322	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
1128398001323	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1128398001324	DDE superfamily endonuclease; Region: DDE_4_2; pfam13613
1128398001325	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001326	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001327	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1128398001328	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
1128398001329	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398001330	active site
1128398001331	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cd02062
1128398001332	FMN binding site [chemical binding]; other site
1128398001333	dimer interface [polypeptide binding]; other site
1128398001334	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
1128398001335	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398001336	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1128398001337	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1128398001338	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
1128398001339	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398001340	FeS/SAM binding site; other site
1128398001341	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
1128398001342	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
1128398001343	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398001344	S-adenosylmethionine binding site [chemical binding]; other site
1128398001345	ParB-like nuclease domain; Region: ParB; smart00470
1128398001346	Recombinase; Region: Recombinase; pfam07508
1128398001347	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1128398001348	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398001349	non-specific DNA binding site [nucleotide binding]; other site
1128398001350	salt bridge; other site
1128398001351	sequence-specific DNA binding site [nucleotide binding]; other site
1128398001352	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1128398001353	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1128398001354	Domain of unknown function (DUF3883); Region: DUF3883; pfam13020
1128398001355	DnaA N-terminal domain; Region: DnaA_N; pfam11638
1128398001356	ATP synthase (F/14-kDa) subunit; Region: ATP-synt_F; cl00632
1128398001357	potassium/proton antiporter; Reviewed; Region: PRK05326
1128398001358	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1128398001359	TrkA-C domain; Region: TrkA_C; pfam02080
1128398001360	TrkA-C domain; Region: TrkA_C; pfam02080
1128398001361	Domain of unknown function (DUF4180); Region: DUF4180; pfam13788
1128398001362	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398001363	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398001364	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1128398001365	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1128398001366	Transposase; Region: HTH_Tnp_1; cl17663
1128398001367	ABC-type enterochelin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: CeuA; COG4607
1128398001368	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001369	intersubunit interface [polypeptide binding]; other site
1128398001370	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398001371	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001372	ABC-ATPase subunit  interface; other site
1128398001373	dimer interface [polypeptide binding]; other site
1128398001374	putative PBP binding regions; other site
1128398001375	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001376	ABC-ATPase subunit  interface; other site
1128398001377	dimer interface [polypeptide binding]; other site
1128398001378	putative PBP binding regions; other site
1128398001379	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
1128398001380	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398001381	Walker A/P-loop; other site
1128398001382	ATP binding site [chemical binding]; other site
1128398001383	Q-loop/lid; other site
1128398001384	ABC transporter signature motif; other site
1128398001385	Walker B; other site
1128398001386	D-loop; other site
1128398001387	H-loop/switch region; other site
1128398001388	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001389	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001390	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001391	Clp protease; Region: CLP_protease; pfam00574
1128398001392	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
1128398001393	oligomer interface [polypeptide binding]; other site
1128398001394	active site residues [active]
1128398001395	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1128398001396	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398001397	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398001398	chloramphenicol/florfenicol resistance protein; Provisional; Region: PRK14453
1128398001399	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
1128398001400	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
1128398001401	DNA binding residues [nucleotide binding]
1128398001402	putative dimer interface [polypeptide binding]; other site
1128398001403	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1128398001404	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1128398001405	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1128398001406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398001407	S-adenosylmethionine binding site [chemical binding]; other site
1128398001408	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001409	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001410	active site
1128398001411	phosphorylation site [posttranslational modification]
1128398001412	intermolecular recognition site; other site
1128398001413	dimerization interface [polypeptide binding]; other site
1128398001414	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001415	DNA binding site [nucleotide binding]
1128398001416	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001417	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398001418	dimerization interface [polypeptide binding]; other site
1128398001419	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398001420	dimer interface [polypeptide binding]; other site
1128398001421	phosphorylation site [posttranslational modification]
1128398001422	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001423	ATP binding site [chemical binding]; other site
1128398001424	Mg2+ binding site [ion binding]; other site
1128398001425	G-X-G motif; other site
1128398001426	Nitroreductase family; Region: Nitroreductase; pfam00881
1128398001427	FMN binding site [chemical binding]; other site
1128398001428	dimer interface [polypeptide binding]; other site
1128398001429	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398001430	Coenzyme A binding pocket [chemical binding]; other site
1128398001431	Helix-turn-helix domain; Region: HTH_18; pfam12833
1128398001432	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
1128398001433	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
1128398001434	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1128398001435	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398001436	S-adenosylmethionine binding site [chemical binding]; other site
1128398001437	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001438	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001439	active site
1128398001440	phosphorylation site [posttranslational modification]
1128398001441	intermolecular recognition site; other site
1128398001442	dimerization interface [polypeptide binding]; other site
1128398001443	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001444	DNA binding site [nucleotide binding]
1128398001445	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001446	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001447	ATP binding site [chemical binding]; other site
1128398001448	Mg2+ binding site [ion binding]; other site
1128398001449	G-X-G motif; other site
1128398001450	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398001451	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398001452	Walker A/P-loop; other site
1128398001453	ATP binding site [chemical binding]; other site
1128398001454	Q-loop/lid; other site
1128398001455	ABC transporter signature motif; other site
1128398001456	Walker B; other site
1128398001457	D-loop; other site
1128398001458	H-loop/switch region; other site
1128398001459	FtsX-like permease family; Region: FtsX; pfam02687
1128398001460	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398001461	FtsX-like permease family; Region: FtsX; pfam02687
1128398001462	Recombinase; Region: Recombinase; pfam07508
1128398001463	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
1128398001464	FAD binding domain; Region: FAD_binding_4; pfam01565
1128398001465	Berberine and berberine like; Region: BBE; pfam08031
1128398001466	Chromate transporter; Region: Chromate_transp; pfam02417
1128398001467	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398001468	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398001469	Probable transposase; Region: OrfB_IS605; pfam01385
1128398001470	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
1128398001471	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398001472	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1128398001473	putative dimerization interface [polypeptide binding]; other site
1128398001474	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398001475	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398001476	Walker A/P-loop; other site
1128398001477	ATP binding site [chemical binding]; other site
1128398001478	Q-loop/lid; other site
1128398001479	ABC transporter signature motif; other site
1128398001480	Walker B; other site
1128398001481	D-loop; other site
1128398001482	H-loop/switch region; other site
1128398001483	FtsX-like permease family; Region: FtsX; pfam02687
1128398001484	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1128398001485	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001486	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001487	active site
1128398001488	phosphorylation site [posttranslational modification]
1128398001489	intermolecular recognition site; other site
1128398001490	dimerization interface [polypeptide binding]; other site
1128398001491	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001492	DNA binding site [nucleotide binding]
1128398001493	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001494	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001495	ATP binding site [chemical binding]; other site
1128398001496	Mg2+ binding site [ion binding]; other site
1128398001497	G-X-G motif; other site
1128398001498	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1128398001499	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001500	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001501	active site
1128398001502	phosphorylation site [posttranslational modification]
1128398001503	intermolecular recognition site; other site
1128398001504	dimerization interface [polypeptide binding]; other site
1128398001505	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001506	DNA binding site [nucleotide binding]
1128398001507	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001508	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398001509	dimerization interface [polypeptide binding]; other site
1128398001510	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398001511	dimer interface [polypeptide binding]; other site
1128398001512	phosphorylation site [posttranslational modification]
1128398001513	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001514	ATP binding site [chemical binding]; other site
1128398001515	Mg2+ binding site [ion binding]; other site
1128398001516	G-X-G motif; other site
1128398001517	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1128398001518	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
1128398001519	active site
1128398001520	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001521	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398001522	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398001523	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398001524	intersubunit interface [polypeptide binding]; other site
1128398001525	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398001526	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001527	ABC-ATPase subunit  interface; other site
1128398001528	dimer interface [polypeptide binding]; other site
1128398001529	putative PBP binding regions; other site
1128398001530	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398001531	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398001532	ABC-ATPase subunit  interface; other site
1128398001533	dimer interface [polypeptide binding]; other site
1128398001534	putative PBP binding regions; other site
1128398001535	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398001536	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398001537	Walker A/P-loop; other site
1128398001538	ATP binding site [chemical binding]; other site
1128398001539	Q-loop/lid; other site
1128398001540	ABC transporter signature motif; other site
1128398001541	Walker B; other site
1128398001542	D-loop; other site
1128398001543	H-loop/switch region; other site
1128398001544	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398001545	H+ Antiporter protein; Region: 2A0121; TIGR00900
1128398001546	putative substrate translocation pore; other site
1128398001547	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1128398001548	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398001549	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
1128398001550	active site
1128398001551	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1128398001552	uracil transporter; Provisional; Region: PRK10720
1128398001553	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1128398001554	cytosine deaminase; Validated; Region: PRK07572
1128398001555	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1128398001556	active site
1128398001557	probable dihydroxyacetone kinase regulator; Region: DHAK_reg; TIGR02366
1128398001558	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398001559	myosin-cross-reactive antigen; Provisional; Region: PRK13977
1128398001560	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1128398001561	putative dimer interface [polypeptide binding]; other site
1128398001562	[2Fe-2S] cluster binding site [ion binding]; other site
1128398001563	Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism]; Region: COG2957; cl01113
1128398001564	Porphyromonas-type peptidyl-arginine deiminase; Region: PAD_porph; pfam04371
1128398001565	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001566	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001567	active site
1128398001568	phosphorylation site [posttranslational modification]
1128398001569	intermolecular recognition site; other site
1128398001570	dimerization interface [polypeptide binding]; other site
1128398001571	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001572	DNA binding site [nucleotide binding]
1128398001573	VanW like protein; Region: VanW; pfam04294
1128398001574	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1128398001575	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1128398001576	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
1128398001577	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
1128398001578	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1128398001579	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1128398001580	alanine racemase; Reviewed; Region: alr; PRK00053
1128398001581	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
1128398001582	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1128398001583	catalytic residue [active]
1128398001584	Uncharacterized conserved protein [Function unknown]; Region: COG0397
1128398001585	hypothetical protein; Validated; Region: PRK00029
1128398001586	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398001587	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398001588	active site
1128398001589	metal binding site [ion binding]; metal-binding site
1128398001590	Sporulation related domain; Region: SPOR; pfam05036
1128398001591	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
1128398001592	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1128398001593	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398001594	Coenzyme A binding pocket [chemical binding]; other site
1128398001595	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398001596	Coenzyme A binding pocket [chemical binding]; other site
1128398001597	hypothetical protein; Reviewed; Region: PRK09588
1128398001598	Uncharacterized protein family UPF0027; Region: UPF0027; cl17455
1128398001599	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
1128398001600	RF-1 domain; Region: RF-1; cl17422
1128398001601	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398001602	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398001603	metal binding site [ion binding]; metal-binding site
1128398001604	active site
1128398001605	I-site; other site
1128398001606	PA: Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain; Region: PA; cl08238
1128398001607	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
1128398001608	Peptidase family M28; Region: Peptidase_M28; pfam04389
1128398001609	metal binding site [ion binding]; metal-binding site
1128398001610	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1128398001611	synthetase active site [active]
1128398001612	NTP binding site [chemical binding]; other site
1128398001613	metal binding site [ion binding]; metal-binding site
1128398001614	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398001615	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398001616	Walker A/P-loop; other site
1128398001617	ATP binding site [chemical binding]; other site
1128398001618	Q-loop/lid; other site
1128398001619	ABC transporter signature motif; other site
1128398001620	Walker B; other site
1128398001621	D-loop; other site
1128398001622	H-loop/switch region; other site
1128398001623	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1128398001624	TraX protein; Region: TraX; cl05434
1128398001625	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398001626	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
1128398001627	Walker A/P-loop; other site
1128398001628	ATP binding site [chemical binding]; other site
1128398001629	Q-loop/lid; other site
1128398001630	ABC transporter signature motif; other site
1128398001631	Walker B; other site
1128398001632	D-loop; other site
1128398001633	H-loop/switch region; other site
1128398001634	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1128398001635	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001636	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001637	active site
1128398001638	phosphorylation site [posttranslational modification]
1128398001639	intermolecular recognition site; other site
1128398001640	dimerization interface [polypeptide binding]; other site
1128398001641	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001642	DNA binding site [nucleotide binding]
1128398001643	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001644	HAMP domain; Region: HAMP; pfam00672
1128398001645	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398001646	dimer interface [polypeptide binding]; other site
1128398001647	phosphorylation site [posttranslational modification]
1128398001648	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001649	ATP binding site [chemical binding]; other site
1128398001650	Mg2+ binding site [ion binding]; other site
1128398001651	G-X-G motif; other site
1128398001652	LysE type translocator; Region: LysE; cl00565
1128398001653	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1128398001654	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398001655	nicotinate phosphoribosyltransferase; Provisional; Region: PRK07188
1128398001656	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
1128398001657	active site
1128398001658	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398001659	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398001660	Coenzyme A binding pocket [chemical binding]; other site
1128398001661	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
1128398001662	putative active site [active]
1128398001663	putative metal binding site [ion binding]; other site
1128398001664	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001665	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001666	ATP binding site [chemical binding]; other site
1128398001667	Mg2+ binding site [ion binding]; other site
1128398001668	G-X-G motif; other site
1128398001669	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398001670	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001671	active site
1128398001672	phosphorylation site [posttranslational modification]
1128398001673	intermolecular recognition site; other site
1128398001674	dimerization interface [polypeptide binding]; other site
1128398001675	YcbB domain; Region: YcbB; pfam08664
1128398001676	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1128398001677	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1128398001678	Rubredoxin [Energy production and conversion]; Region: COG1773
1128398001679	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
1128398001680	iron binding site [ion binding]; other site
1128398001681	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1128398001682	Conserved region in glutamate synthase; Region: Glu_synthase; pfam01645
1128398001683	active site
1128398001684	FMN binding site [chemical binding]; other site
1128398001685	substrate binding site [chemical binding]; other site
1128398001686	3Fe-4S cluster binding site [ion binding]; other site
1128398001687	Domain of unknown function (DUF4282); Region: DUF4282; pfam14110
1128398001688	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1128398001689	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398001690	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398001691	DNA binding residues [nucleotide binding]
1128398001692	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398001693	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398001694	metal binding site [ion binding]; metal-binding site
1128398001695	active site
1128398001696	I-site; other site
1128398001697	Predicted acetamidase/formamidase [Energy production and conversion]; Region: COG2421
1128398001698	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398001699	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398001700	active site
1128398001701	phosphorylation site [posttranslational modification]
1128398001702	intermolecular recognition site; other site
1128398001703	dimerization interface [polypeptide binding]; other site
1128398001704	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398001705	DNA binding site [nucleotide binding]
1128398001706	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398001707	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398001708	dimerization interface [polypeptide binding]; other site
1128398001709	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398001710	dimer interface [polypeptide binding]; other site
1128398001711	phosphorylation site [posttranslational modification]
1128398001712	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001713	ATP binding site [chemical binding]; other site
1128398001714	Mg2+ binding site [ion binding]; other site
1128398001715	G-X-G motif; other site
1128398001716	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398001717	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398001718	Walker A/P-loop; other site
1128398001719	ATP binding site [chemical binding]; other site
1128398001720	Q-loop/lid; other site
1128398001721	ABC transporter signature motif; other site
1128398001722	Walker B; other site
1128398001723	D-loop; other site
1128398001724	H-loop/switch region; other site
1128398001725	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1128398001726	FtsX-like permease family; Region: FtsX; pfam02687
1128398001727	RNA polymerase sigma factor; Provisional; Region: PRK12543
1128398001728	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398001729	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398001730	DNA binding residues [nucleotide binding]
1128398001731	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1128398001732	AIR carboxylase; Region: AIRC; pfam00731
1128398001733	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398001734	active site
1128398001735	thiamine biosynthesis protein ThiC; Provisional; Region: PRK13352
1128398001736	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
1128398001737	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
1128398001738	Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155
1128398001739	putative ligand binding site [chemical binding]; other site
1128398001740	NAD binding site [chemical binding]; other site
1128398001741	catalytic site [active]
1128398001742	cytosine deaminase; Provisional; Region: PRK09230
1128398001743	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1128398001744	active site
1128398001745	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
1128398001746	FOG: CBS domain [General function prediction only]; Region: COG0517
1128398001747	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection...; Region: CBS_pair_BON_assoc; cd04586
1128398001748	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
1128398001749	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398001750	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398001751	DNA binding site [nucleotide binding]
1128398001752	active site
1128398001753	Int/Topo IB signature motif; other site
1128398001754	heat shock protein 90; Provisional; Region: PRK05218
1128398001755	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398001756	ATP binding site [chemical binding]; other site
1128398001757	Mg2+ binding site [ion binding]; other site
1128398001758	G-X-G motif; other site
1128398001759	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1128398001760	putative efflux protein, MATE family; Region: matE; TIGR00797
1128398001761	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1128398001762	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
1128398001763	GAF domain; Region: GAF; pfam01590
1128398001764	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398001765	Zn2+ binding site [ion binding]; other site
1128398001766	Mg2+ binding site [ion binding]; other site
1128398001767	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1128398001768	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
1128398001769	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
1128398001770	Found in ATP-dependent protease La (LON); Region: LON; smart00464
1128398001771	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398001772	Walker A motif; other site
1128398001773	ATP binding site [chemical binding]; other site
1128398001774	Walker B motif; other site
1128398001775	arginine finger; other site
1128398001776	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1128398001777	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
1128398001778	G1 box; other site
1128398001779	GTP/Mg2+ binding site [chemical binding]; other site
1128398001780	Switch I region; other site
1128398001781	G2 box; other site
1128398001782	G3 box; other site
1128398001783	Switch II region; other site
1128398001784	G4 box; other site
1128398001785	G5 box; other site
1128398001786	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1128398001787	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1128398001788	S-layer homology domain; Region: SLH; pfam00395
1128398001789	S-layer homology domain; Region: SLH; pfam00395
1128398001790	germination protein YpeB; Region: spore_YpeB; TIGR02889
1128398001791	S-layer homology domain; Region: SLH; pfam00395
1128398001792	S-layer homology domain; Region: SLH; pfam00395
1128398001793	Holin family; Region: Phage_holin_4; pfam05105
1128398001794	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1128398001795	catalytic core [active]
1128398001796	NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion]; Region: NuoE; COG1905
1128398001797	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1128398001798	putative dimer interface [polypeptide binding]; other site
1128398001799	[2Fe-2S] cluster binding site [ion binding]; other site
1128398001800	CobQ/CobB/MinD/ParA nucleotide binding domain; Region: CbiA; pfam01656
1128398001801	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398001802	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398001803	cobalamin biosynthesis protein; Provisional; Region: cobD; PRK01209
1128398001804	threonine-phosphate decarboxylase; Provisional; Region: PRK06358
1128398001805	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398001806	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398001807	homodimer interface [polypeptide binding]; other site
1128398001808	catalytic residue [active]
1128398001809	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
1128398001810	homotrimer interface [polypeptide binding]; other site
1128398001811	Walker A motif; other site
1128398001812	GTP binding site [chemical binding]; other site
1128398001813	Walker B motif; other site
1128398001814	cobalamin synthase; Reviewed; Region: cobS; PRK00235
1128398001815	Pirin-related protein [General function prediction only]; Region: COG1741
1128398001816	Pirin; Region: Pirin; pfam02678
1128398001817	Pirin C-terminal cupin domain; Region: Pirin_C; pfam05726
1128398001818	ornithine cyclodeaminase; Validated; Region: PRK08618
1128398001819	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
1128398001820	tol-pal system beta propeller repeat protein TolB; Region: propeller_TolB; TIGR02800
1128398001821	translocation protein TolB; Provisional; Region: tolB; PRK03629
1128398001822	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
1128398001823	hypothetical protein; Provisional; Region: PRK00955
1128398001824	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
1128398001825	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
1128398001826	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
1128398001827	G1 box; other site
1128398001828	putative GEF interaction site [polypeptide binding]; other site
1128398001829	GTP/Mg2+ binding site [chemical binding]; other site
1128398001830	Switch I region; other site
1128398001831	G2 box; other site
1128398001832	G3 box; other site
1128398001833	Switch II region; other site
1128398001834	G4 box; other site
1128398001835	G5 box; other site
1128398001836	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
1128398001837	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
1128398001838	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1128398001839	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
1128398001840	homodimer interface [polypeptide binding]; other site
1128398001841	substrate-cofactor binding pocket; other site
1128398001842	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398001843	catalytic residue [active]
1128398001844	oligoendopeptidase, pepF/M3 family; Region: M3_fam_3; TIGR02290
1128398001845	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_2; cd09607
1128398001846	active site
1128398001847	Zn binding site [ion binding]; other site
1128398001848	peroxiredoxin; Provisional; Region: PRK13189
1128398001849	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
1128398001850	dimer interface [polypeptide binding]; other site
1128398001851	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1128398001852	catalytic triad [active]
1128398001853	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
1128398001854	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398001855	Walker A/P-loop; other site
1128398001856	ATP binding site [chemical binding]; other site
1128398001857	Q-loop/lid; other site
1128398001858	ABC transporter signature motif; other site
1128398001859	Walker B; other site
1128398001860	D-loop; other site
1128398001861	H-loop/switch region; other site
1128398001862	Cysteine-rich small domain; Region: zf-like; cl00946
1128398001863	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
1128398001864	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
1128398001865	active site
1128398001866	dimer interface [polypeptide binding]; other site
1128398001867	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
1128398001868	dimer interface [polypeptide binding]; other site
1128398001869	active site
1128398001870	glycogen branching enzyme; Provisional; Region: PRK12313
1128398001871	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
1128398001872	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
1128398001873	active site
1128398001874	catalytic site [active]
1128398001875	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
1128398001876	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398001877	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398001878	Probable transposase; Region: OrfB_IS605; pfam01385
1128398001879	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398001880	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
1128398001881	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1128398001882	ligand binding site; other site
1128398001883	oligomer interface; other site
1128398001884	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1128398001885	dimer interface [polypeptide binding]; other site
1128398001886	N-terminal domain interface [polypeptide binding]; other site
1128398001887	sulfate 1 binding site; other site
1128398001888	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
1128398001889	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
1128398001890	ligand binding site; other site
1128398001891	oligomer interface; other site
1128398001892	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
1128398001893	dimer interface [polypeptide binding]; other site
1128398001894	N-terminal domain interface [polypeptide binding]; other site
1128398001895	sulfate 1 binding site; other site
1128398001896	glycogen synthase; Provisional; Region: glgA; PRK00654
1128398001897	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
1128398001898	ADP-binding pocket [chemical binding]; other site
1128398001899	homodimer interface [polypeptide binding]; other site
1128398001900	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
1128398001901	homodimer interface [polypeptide binding]; other site
1128398001902	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
1128398001903	active site pocket [active]
1128398001904	Early set domain associated with the catalytic domain of sugar utilizing enzymes at either the N or C terminus; Region: E_set; cl09101
1128398001905	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
1128398001906	Glycosidases [Carbohydrate transport and metabolism]; Region: AmyA; COG0366
1128398001907	active site
1128398001908	homodimer interface [polypeptide binding]; other site
1128398001909	catalytic site [active]
1128398001910	Protein of unknown function (DUF3888); Region: DUF3888; pfam13027
1128398001911	D,D-heptose 1,7-bisphosphate phosphatase; Validated; Region: PRK08942
1128398001912	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1128398001913	active site
1128398001914	motif I; other site
1128398001915	motif II; other site
1128398001916	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
1128398001917	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
1128398001918	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1128398001919	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1128398001920	protein binding site [polypeptide binding]; other site
1128398001921	Predicted membrane protein [Function unknown]; Region: COG2323
1128398001922	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
1128398001923	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
1128398001924	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1128398001925	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
1128398001926	active site
1128398001927	dimer interface [polypeptide binding]; other site
1128398001928	motif 1; other site
1128398001929	motif 2; other site
1128398001930	motif 3; other site
1128398001931	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
1128398001932	anticodon binding site; other site
1128398001933	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3864
1128398001934	Putative metallopeptidase domain; Region: DUF2201_N; pfam13203
1128398001935	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398001936	Walker A motif; other site
1128398001937	ATP binding site [chemical binding]; other site
1128398001938	Walker B motif; other site
1128398001939	arginine finger; other site
1128398001940	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1128398001941	RNA methyltransferase, RsmE family; Region: TIGR00046
1128398001942	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398001943	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1128398001944	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398001945	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
1128398001946	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1128398001947	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1128398001948	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398001949	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398001950	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
1128398001951	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398001952	active site
1128398001953	HIGH motif; other site
1128398001954	nucleotide binding site [chemical binding]; other site
1128398001955	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
1128398001956	active site
1128398001957	KMSKS motif; other site
1128398001958	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
1128398001959	tRNA binding surface [nucleotide binding]; other site
1128398001960	anticodon binding site; other site
1128398001961	Predicted transcriptional regulator [Transcription]; Region: COG2378
1128398001962	HTH domain; Region: HTH_11; pfam08279
1128398001963	WYL domain; Region: WYL; pfam13280
1128398001964	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
1128398001965	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cd09754
1128398001966	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cl09909
1128398001967	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
1128398001968	CRISPR-associated autoregulator DevR family; Region: cas_MJ0381; TIGR01875
1128398001969	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I; cl12040
1128398001970	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
1128398001971	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1128398001972	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
1128398001973	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
1128398001974	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
1128398001975	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
1128398001976	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1128398001977	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
1128398001978	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1128398001979	FMN binding site [chemical binding]; other site
1128398001980	dimer interface [polypeptide binding]; other site
1128398001981	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398001982	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1128398001983	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
1128398001984	NodB motif; other site
1128398001985	active site
1128398001986	catalytic site [active]
1128398001987	Zn binding site [ion binding]; other site
1128398001988	EDD domain protein, DegV family; Region: DegV; TIGR00762
1128398001989	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1128398001990	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
1128398001991	Herpesviridae UL52/UL70 DNA primase; Region: Herpes_UL52; cl17300
1128398001992	Family description; Region: UvrD_C_2; pfam13538
1128398001993	GPI biosynthesis protein family Pig-F; Region: PIG-F; pfam06699
1128398001994	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398001995	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398001996	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
1128398001997	Walker A/P-loop; other site
1128398001998	ATP binding site [chemical binding]; other site
1128398001999	Q-loop/lid; other site
1128398002000	ABC transporter signature motif; other site
1128398002001	Walker B; other site
1128398002002	D-loop; other site
1128398002003	H-loop/switch region; other site
1128398002004	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
1128398002005	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1128398002006	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
1128398002007	active site
1128398002008	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1128398002009	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398002010	substrate binding pocket [chemical binding]; other site
1128398002011	membrane-bound complex binding site; other site
1128398002012	hinge residues; other site
1128398002013	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1128398002014	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002015	dimer interface [polypeptide binding]; other site
1128398002016	conserved gate region; other site
1128398002017	putative PBP binding loops; other site
1128398002018	ABC-ATPase subunit interface; other site
1128398002019	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
1128398002020	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
1128398002021	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
1128398002022	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1128398002023	metal-binding site [ion binding]
1128398002024	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398002025	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1128398002026	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
1128398002027	M28 Zn-Peptidases containing a PA domain insert; Region: M28_like_PA; cd03877
1128398002028	Peptidase family M28; Region: Peptidase_M28; pfam04389
1128398002029	metal binding site [ion binding]; metal-binding site
1128398002030	Hemerythrin-like domain; Region: Hr-like; cd12108
1128398002031	Fe binding site [ion binding]; other site
1128398002032	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1128398002033	Carbon monoxide dehydrogenase (CODH) is found in acetogenic and methanogenic organisms and is responsible for the synthesis and breakdown of acetyl-CoA, respectively. CODH has two types of metal clusters, a cubane [Fe4-S4] center (B-cluster) similar to...; Region: CODH; cd01915
1128398002034	carbon-monoxide dehydrogenase, catalytic subunit; Region: CO_DH_cata; TIGR01702
1128398002035	ACS interaction site; other site
1128398002036	CODH interaction site; other site
1128398002037	cubane metal cluster (B-cluster) [ion binding]; other site
1128398002038	Ni-Fe-S cluster (C-cluster) [ion binding]; other site
1128398002039	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398002040	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002041	dimer interface [polypeptide binding]; other site
1128398002042	conserved gate region; other site
1128398002043	putative PBP binding loops; other site
1128398002044	ABC-ATPase subunit interface; other site
1128398002045	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398002046	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398002047	Walker A/P-loop; other site
1128398002048	ATP binding site [chemical binding]; other site
1128398002049	Q-loop/lid; other site
1128398002050	ABC transporter signature motif; other site
1128398002051	Walker B; other site
1128398002052	D-loop; other site
1128398002053	H-loop/switch region; other site
1128398002054	Clostripain family; Region: Peptidase_C11; pfam03415
1128398002055	Peptidase associated domain: C-terminal domain of M14 N/E carboxypeptidase; putative folding, regulation, or interaction domain; Region: Peptidase_M14NE-CP-C_like; cl17499
1128398002056	tRNA pseudouridine synthase A; Reviewed; Region: PRK12434
1128398002057	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1128398002058	dimerization interface 3.5A [polypeptide binding]; other site
1128398002059	active site
1128398002060	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
1128398002061	active site
1128398002062	FMN binding site [chemical binding]; other site
1128398002063	substrate binding site [chemical binding]; other site
1128398002064	3Fe-4S cluster binding site [ion binding]; other site
1128398002065	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
1128398002066	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
1128398002067	active site
1128398002068	trimer interface [polypeptide binding]; other site
1128398002069	allosteric site; other site
1128398002070	active site lid [active]
1128398002071	hexamer (dimer of trimers) interface [polypeptide binding]; other site
1128398002072	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1128398002073	YCII-related domain; Region: YCII; cl00999
1128398002074	AzlC protein; Region: AzlC; pfam03591
1128398002075	xanthine permease; Region: pbuX; TIGR03173
1128398002076	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1128398002077	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1128398002078	active site
1128398002079	metal binding site [ion binding]; metal-binding site
1128398002080	DNA binding site [nucleotide binding]
1128398002081	AAA domain; Region: AAA_23; pfam13476
1128398002082	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1128398002083	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
1128398002084	active site
1128398002085	metal binding site [ion binding]; metal-binding site
1128398002086	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
1128398002087	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
1128398002088	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
1128398002089	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398002090	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002091	active site
1128398002092	phosphorylation site [posttranslational modification]
1128398002093	intermolecular recognition site; other site
1128398002094	dimerization interface [polypeptide binding]; other site
1128398002095	LytTr DNA-binding domain; Region: LytTR; smart00850
1128398002096	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398002097	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002098	active site
1128398002099	phosphorylation site [posttranslational modification]
1128398002100	intermolecular recognition site; other site
1128398002101	dimerization interface [polypeptide binding]; other site
1128398002102	LytTr DNA-binding domain; Region: LytTR; smart00850
1128398002103	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398002104	ATP binding site [chemical binding]; other site
1128398002105	Mg2+ binding site [ion binding]; other site
1128398002106	G-X-G motif; other site
1128398002107	Accessory gene regulator B; Region: AgrB; pfam04647
1128398002108	anthranilate synthase component I; Provisional; Region: PRK13570
1128398002109	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1128398002110	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
1128398002111	anthranilate phosphoribosyltransferase; Provisional; Region: trpD; PRK00188
1128398002112	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1128398002113	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1128398002114	Indole-3-glycerol phosphate synthase (IGPS); an enzyme in the tryptophan biosynthetic pathway, catalyzing the ring closure reaction of 1-(o-carboxyphenylamino)-1-deoxyribulose-5-phosphate (CdRP) to indole-3-glycerol phosphate (IGP), accompanied by the...; Region: IGPS; cd00331
1128398002115	active site
1128398002116	ribulose/triose binding site [chemical binding]; other site
1128398002117	phosphate binding site [ion binding]; other site
1128398002118	substrate (anthranilate) binding pocket [chemical binding]; other site
1128398002119	product (indole) binding pocket [chemical binding]; other site
1128398002120	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
1128398002121	active site
1128398002122	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
1128398002123	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
1128398002124	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398002125	catalytic residue [active]
1128398002126	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
1128398002127	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
1128398002128	substrate binding site [chemical binding]; other site
1128398002129	active site
1128398002130	catalytic residues [active]
1128398002131	heterodimer interface [polypeptide binding]; other site
1128398002132	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
1128398002133	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
1128398002134	zinc binding site [ion binding]; other site
1128398002135	putative ligand binding site [chemical binding]; other site
1128398002136	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398002137	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398002138	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398002139	Walker A/P-loop; other site
1128398002140	ATP binding site [chemical binding]; other site
1128398002141	Q-loop/lid; other site
1128398002142	ABC transporter signature motif; other site
1128398002143	Walker B; other site
1128398002144	D-loop; other site
1128398002145	H-loop/switch region; other site
1128398002146	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398002147	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398002148	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1128398002149	Walker A/P-loop; other site
1128398002150	ATP binding site [chemical binding]; other site
1128398002151	Q-loop/lid; other site
1128398002152	ABC transporter signature motif; other site
1128398002153	Walker B; other site
1128398002154	D-loop; other site
1128398002155	H-loop/switch region; other site
1128398002156	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
1128398002157	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1128398002158	FMN binding site [chemical binding]; other site
1128398002159	substrate binding site [chemical binding]; other site
1128398002160	putative catalytic residue [active]
1128398002161	Adenylyl cyclase (AC) class IV-like, a subgroup of the CYTH-like superfamily; Region: CYTH-like_AC_IV-like; cd07890
1128398002162	putative active site [active]
1128398002163	putative metal binding residues [ion binding]; other site
1128398002164	signature motif; other site
1128398002165	putative triphosphate binding site [ion binding]; other site
1128398002166	dimer interface [polypeptide binding]; other site
1128398002167	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1128398002168	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
1128398002169	Domain of unknown function (DUF378); Region: DUF378; pfam04070
1128398002170	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398002171	Domain of unknown function (DUF3391); Region: DUF3391; pfam11871
1128398002172	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398002173	Zn2+ binding site [ion binding]; other site
1128398002174	Mg2+ binding site [ion binding]; other site
1128398002175	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
1128398002176	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002177	FeS/SAM binding site; other site
1128398002178	argininosuccinate synthase; Provisional; Region: PRK13820
1128398002179	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
1128398002180	ANP binding site [chemical binding]; other site
1128398002181	Substrate Binding Site II [chemical binding]; other site
1128398002182	Substrate Binding Site I [chemical binding]; other site
1128398002183	argininosuccinate lyase; Provisional; Region: PRK00855
1128398002184	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
1128398002185	active sites [active]
1128398002186	tetramer interface [polypeptide binding]; other site
1128398002187	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3879
1128398002188	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1128398002189	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
1128398002190	phosphoenolpyruvate synthase; Validated; Region: PRK06464
1128398002191	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
1128398002192	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1128398002193	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
1128398002194	putative acetyltransferase; Provisional; Region: PRK03624
1128398002195	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398002196	Coenzyme A binding pocket [chemical binding]; other site
1128398002197	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
1128398002198	Predicted transcriptional regulators [Transcription]; Region: COG1695
1128398002199	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1128398002200	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1128398002201	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1128398002202	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1128398002203	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002204	ABC-ATPase subunit interface; other site
1128398002205	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
1128398002206	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1128398002207	Walker A/P-loop; other site
1128398002208	ATP binding site [chemical binding]; other site
1128398002209	Q-loop/lid; other site
1128398002210	ABC transporter signature motif; other site
1128398002211	Walker B; other site
1128398002212	D-loop; other site
1128398002213	H-loop/switch region; other site
1128398002214	NIL domain; Region: NIL; pfam09383
1128398002215	Coat F domain; Region: Coat_F; pfam07875
1128398002216	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
1128398002217	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1128398002218	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1128398002219	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
1128398002220	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
1128398002221	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
1128398002222	dihydroorotase; Validated; Region: pyrC; PRK09357
1128398002223	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398002224	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
1128398002225	active site
1128398002226	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
1128398002227	active site
1128398002228	dimer interface [polypeptide binding]; other site
1128398002229	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
1128398002230	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
1128398002231	FAD binding pocket [chemical binding]; other site
1128398002232	FAD binding motif [chemical binding]; other site
1128398002233	phosphate binding motif [ion binding]; other site
1128398002234	beta-alpha-beta structure motif; other site
1128398002235	NAD binding pocket [chemical binding]; other site
1128398002236	Iron coordination center [ion binding]; other site
1128398002237	dihydroorotate dehydrogenase (subfamily 1) family protein; Region: pyrD_sub1_fam; TIGR01037
1128398002238	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
1128398002239	heterodimer interface [polypeptide binding]; other site
1128398002240	active site
1128398002241	FMN binding site [chemical binding]; other site
1128398002242	homodimer interface [polypeptide binding]; other site
1128398002243	substrate binding site [chemical binding]; other site
1128398002244	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398002245	active site
1128398002246	Chloramphenicol O-acetyltransferase [Defense mechanisms]; Region: COG4845
1128398002247	Chloramphenicol acetyltransferase; Region: CAT; cl02008
1128398002248	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1128398002249	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398002250	non-specific DNA binding site [nucleotide binding]; other site
1128398002251	salt bridge; other site
1128398002252	sequence-specific DNA binding site [nucleotide binding]; other site
1128398002253	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398002254	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398002255	S-adenosylmethionine binding site [chemical binding]; other site
1128398002256	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1128398002257	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398002258	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002259	dimer interface [polypeptide binding]; other site
1128398002260	conserved gate region; other site
1128398002261	putative PBP binding loops; other site
1128398002262	ABC-ATPase subunit interface; other site
1128398002263	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398002264	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398002265	Walker A/P-loop; other site
1128398002266	ATP binding site [chemical binding]; other site
1128398002267	Q-loop/lid; other site
1128398002268	ABC transporter signature motif; other site
1128398002269	Walker B; other site
1128398002270	D-loop; other site
1128398002271	H-loop/switch region; other site
1128398002272	Arylsulfotransferase (ASST); Region: Arylsulfotrans; pfam05935
1128398002273	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398002274	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002275	dimer interface [polypeptide binding]; other site
1128398002276	conserved gate region; other site
1128398002277	putative PBP binding loops; other site
1128398002278	ABC-ATPase subunit interface; other site
1128398002279	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398002280	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398002281	Walker A/P-loop; other site
1128398002282	ATP binding site [chemical binding]; other site
1128398002283	Q-loop/lid; other site
1128398002284	ABC transporter signature motif; other site
1128398002285	Walker B; other site
1128398002286	D-loop; other site
1128398002287	H-loop/switch region; other site
1128398002288	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1128398002289	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398002290	substrate binding pocket [chemical binding]; other site
1128398002291	membrane-bound complex binding site; other site
1128398002292	hinge residues; other site
1128398002293	Arylsulfotransferase (ASST); Region: Arylsulfotran_2; pfam14269
1128398002294	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398002295	S-adenosylmethionine binding site [chemical binding]; other site
1128398002296	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
1128398002297	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398002298	dimerization interface [polypeptide binding]; other site
1128398002299	putative DNA binding site [nucleotide binding]; other site
1128398002300	putative Zn2+ binding site [ion binding]; other site
1128398002301	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1128398002302	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1128398002303	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
1128398002304	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
1128398002305	Walker A motif; other site
1128398002306	ATP binding site [chemical binding]; other site
1128398002307	Walker B motif; other site
1128398002308	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1128398002309	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1128398002310	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1128398002311	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1128398002312	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1128398002313	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398002314	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398002315	Probable transposase; Region: OrfB_IS605; pfam01385
1128398002316	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398002317	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1128398002318	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1128398002319	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1128398002320	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
1128398002321	Fimbrial assembly protein (PilN); Region: PilN; pfam05137
1128398002322	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
1128398002323	GSH binding site [chemical binding]; other site
1128398002324	catalytic residues [active]
1128398002325	molybdenum-pterin binding domain; Region: Mop; TIGR00638
1128398002326	Cache domain; Region: Cache_1; pfam02743
1128398002327	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1128398002328	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398002329	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398002330	dimer interface [polypeptide binding]; other site
1128398002331	putative CheW interface [polypeptide binding]; other site
1128398002332	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398002333	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398002334	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1128398002335	active site residue [active]
1128398002336	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1128398002337	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1128398002338	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
1128398002339	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
1128398002340	putative metal binding site; other site
1128398002341	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
1128398002342	binding surface
1128398002343	TPR motif; other site
1128398002344	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398002345	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1128398002346	substrate binding pocket [chemical binding]; other site
1128398002347	membrane-bound complex binding site; other site
1128398002348	hinge residues; other site
1128398002349	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002350	dimer interface [polypeptide binding]; other site
1128398002351	conserved gate region; other site
1128398002352	putative PBP binding loops; other site
1128398002353	ABC-ATPase subunit interface; other site
1128398002354	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1128398002355	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1128398002356	Walker A/P-loop; other site
1128398002357	ATP binding site [chemical binding]; other site
1128398002358	Q-loop/lid; other site
1128398002359	ABC transporter signature motif; other site
1128398002360	Walker B; other site
1128398002361	D-loop; other site
1128398002362	H-loop/switch region; other site
1128398002363	Zinc finger domain containing protein (CDGSH-type) [Function unknown]; Region: COG3369
1128398002364	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
1128398002365	Protein of unknown function (DUF1271); Region: DUF1271; cl01443
1128398002366	Iron-binding zinc finger CDGSH type; Region: zf-CDGSH; pfam09360
1128398002367	Cache domain; Region: Cache_1; pfam02743
1128398002368	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1128398002369	dimerization interface [polypeptide binding]; other site
1128398002370	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398002371	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398002372	dimer interface [polypeptide binding]; other site
1128398002373	putative CheW interface [polypeptide binding]; other site
1128398002374	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1128398002375	Protein of unknown function (DUF523); Region: DUF523; cl00733
1128398002376	Fic/DOC family; Region: Fic; cl00960
1128398002377	2-isopropylmalate synthase; Validated; Region: PRK00915
1128398002378	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1128398002379	active site
1128398002380	catalytic residues [active]
1128398002381	metal binding site [ion binding]; metal-binding site
1128398002382	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1128398002383	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
1128398002384	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1128398002385	DNA binding residues [nucleotide binding]
1128398002386	drug binding residues [chemical binding]; other site
1128398002387	dimer interface [polypeptide binding]; other site
1128398002388	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1128398002389	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1128398002390	homotrimer interaction site [polypeptide binding]; other site
1128398002391	putative active site [active]
1128398002392	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1128398002393	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398002394	Coenzyme A binding pocket [chemical binding]; other site
1128398002395	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1128398002396	active site
1128398002397	catalytic motif [active]
1128398002398	Zn binding site [ion binding]; other site
1128398002399	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398002400	Uncharacterized protein family (UPF0157); Region: UPF0157; pfam04229
1128398002401	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398002402	Coenzyme A binding pocket [chemical binding]; other site
1128398002403	CAAX protease self-immunity; Region: Abi; pfam02517
1128398002404	Predicted transcriptional regulators [Transcription]; Region: COG1695
1128398002405	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1128398002406	Acetamidase/Formamidase family; Region: FmdA_AmdA; pfam03069
1128398002407	methionine aminopeptidase; Provisional; Region: PRK12318
1128398002408	SEC-C motif; Region: SEC-C; pfam02810
1128398002409	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1128398002410	active site
1128398002411	Mor transcription activator family; Region: Mor; cl02360
1128398002412	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1128398002413	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398002414	Walker A/P-loop; other site
1128398002415	ATP binding site [chemical binding]; other site
1128398002416	Q-loop/lid; other site
1128398002417	ABC transporter signature motif; other site
1128398002418	Walker B; other site
1128398002419	D-loop; other site
1128398002420	H-loop/switch region; other site
1128398002421	ABC transporter; Region: ABC_tran_2; pfam12848
1128398002422	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398002423	phosphonate metabolim protein, transferase hexapeptide repeat family; Region: phn_thr-fam; TIGR03308
1128398002424	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1128398002425	trimer interface [polypeptide binding]; other site
1128398002426	active site
1128398002427	substrate binding site [chemical binding]; other site
1128398002428	CoA binding site [chemical binding]; other site
1128398002429	Predicted membrane protein [Function unknown]; Region: COG2364
1128398002430	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398002431	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398002432	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398002433	non-specific DNA binding site [nucleotide binding]; other site
1128398002434	salt bridge; other site
1128398002435	sequence-specific DNA binding site [nucleotide binding]; other site
1128398002436	Cupin domain; Region: Cupin_2; pfam07883
1128398002437	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
1128398002438	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1128398002439	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1128398002440	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398002441	non-specific DNA binding site [nucleotide binding]; other site
1128398002442	salt bridge; other site
1128398002443	sequence-specific DNA binding site [nucleotide binding]; other site
1128398002444	Predicted transcriptional regulator [Transcription]; Region: COG2378
1128398002445	HTH domain; Region: HTH_11; pfam08279
1128398002446	WYL domain; Region: WYL; pfam13280
1128398002447	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1128398002448	Mannose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Region: {ManC}; COG0662
1128398002449	Predicted membrane protein [Function unknown]; Region: COG2323
1128398002450	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
1128398002451	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398002452	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002453	active site
1128398002454	phosphorylation site [posttranslational modification]
1128398002455	intermolecular recognition site; other site
1128398002456	dimerization interface [polypeptide binding]; other site
1128398002457	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398002458	DNA binding site [nucleotide binding]
1128398002459	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398002460	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398002461	dimer interface [polypeptide binding]; other site
1128398002462	phosphorylation site [posttranslational modification]
1128398002463	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398002464	ATP binding site [chemical binding]; other site
1128398002465	Mg2+ binding site [ion binding]; other site
1128398002466	G-X-G motif; other site
1128398002467	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398002468	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398002469	Walker A/P-loop; other site
1128398002470	ATP binding site [chemical binding]; other site
1128398002471	Q-loop/lid; other site
1128398002472	ABC transporter signature motif; other site
1128398002473	Walker B; other site
1128398002474	D-loop; other site
1128398002475	H-loop/switch region; other site
1128398002476	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398002477	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398002478	FtsX-like permease family; Region: FtsX; pfam02687
1128398002479	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
1128398002480	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002481	FeS/SAM binding site; other site
1128398002482	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1128398002483	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
1128398002484	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002485	FeS/SAM binding site; other site
1128398002486	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1128398002487	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002488	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
1128398002489	FeS/SAM binding site; other site
1128398002490	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1128398002491	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002492	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1128398002493	FeS/SAM binding site; other site
1128398002494	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1128398002495	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002496	FeS/SAM binding site; other site
1128398002497	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1128398002498	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398002499	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398002500	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398002501	Walker A/P-loop; other site
1128398002502	ATP binding site [chemical binding]; other site
1128398002503	Q-loop/lid; other site
1128398002504	ABC transporter signature motif; other site
1128398002505	Walker B; other site
1128398002506	D-loop; other site
1128398002507	H-loop/switch region; other site
1128398002508	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398002509	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002510	active site
1128398002511	phosphorylation site [posttranslational modification]
1128398002512	intermolecular recognition site; other site
1128398002513	dimerization interface [polypeptide binding]; other site
1128398002514	LytTr DNA-binding domain; Region: LytTR; pfam04397
1128398002515	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1128398002516	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1128398002517	Accessory gene regulator B; Region: AgrB; cl01873
1128398002518	Staphylococcal AgrD protein; Region: AgrD; cl05477
1128398002519	isoaspartyl dipeptidase; Provisional; Region: PRK10657
1128398002520	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398002521	active site
1128398002522	Type 1 glutamine amidotransferase (GATase1)-like domain found in cyanophycinase; Region: GAT1_cyanophycinase; cd03145
1128398002523	proposed catalytic triad [active]
1128398002524	active site nucleophile [active]
1128398002525	cyanophycin synthetase; Provisional; Region: PRK14016
1128398002526	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1128398002527	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398002528	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398002529	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398002530	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398002531	dimer interface [polypeptide binding]; other site
1128398002532	phosphorylation site [posttranslational modification]
1128398002533	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398002534	ATP binding site [chemical binding]; other site
1128398002535	Mg2+ binding site [ion binding]; other site
1128398002536	G-X-G motif; other site
1128398002537	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398002538	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398002539	TIGR03987 family protein; Region: TIGR03987
1128398002540	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1128398002541	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398002542	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1128398002543	PemK-like protein; Region: PemK; pfam02452
1128398002544	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398002545	non-specific DNA binding site [nucleotide binding]; other site
1128398002546	salt bridge; other site
1128398002547	sequence-specific DNA binding site [nucleotide binding]; other site
1128398002548	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
1128398002549	C-5 cytosine-specific DNA methylase; Region: DNA_methylase; pfam00145
1128398002550	cofactor binding site; other site
1128398002551	DNA binding site [nucleotide binding]
1128398002552	substrate interaction site [chemical binding]; other site
1128398002553	Eco47II restriction endonuclease; Region: RE_Eco47II; pfam09553
1128398002554	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1128398002555	DNA-binding site [nucleotide binding]; DNA binding site
1128398002556	RNA-binding motif; other site
1128398002557	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
1128398002558	Sulfatase; Region: Sulfatase; cl17466
1128398002559	Molybdopterin-binding protein [Coenzyme metabolism]; Region: MopI; COG3585
1128398002560	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398002561	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002562	active site
1128398002563	phosphorylation site [posttranslational modification]
1128398002564	intermolecular recognition site; other site
1128398002565	dimerization interface [polypeptide binding]; other site
1128398002566	LytTr DNA-binding domain; Region: LytTR; smart00850
1128398002567	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398002568	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1128398002569	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398002570	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398002571	FtsX-like permease family; Region: FtsX; pfam02687
1128398002572	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398002573	FtsX-like permease family; Region: FtsX; pfam02687
1128398002574	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181
1128398002575	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398002576	Walker A/P-loop; other site
1128398002577	ATP binding site [chemical binding]; other site
1128398002578	Q-loop/lid; other site
1128398002579	ABC transporter signature motif; other site
1128398002580	Walker B; other site
1128398002581	D-loop; other site
1128398002582	H-loop/switch region; other site
1128398002583	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398002584	FtsX-like permease family; Region: FtsX; pfam02687
1128398002585	FtsX-like permease family; Region: FtsX; pfam02687
1128398002586	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398002587	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398002588	Walker A/P-loop; other site
1128398002589	ATP binding site [chemical binding]; other site
1128398002590	Q-loop/lid; other site
1128398002591	ABC transporter signature motif; other site
1128398002592	Walker B; other site
1128398002593	D-loop; other site
1128398002594	H-loop/switch region; other site
1128398002595	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
1128398002596	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
1128398002597	catalytic residues [active]
1128398002598	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1128398002599	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
1128398002600	DNA binding residues [nucleotide binding]
1128398002601	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
1128398002602	catalytic residues [active]
1128398002603	catalytic nucleophile [active]
1128398002604	Predicted membrane protein [Function unknown]; Region: COG1511
1128398002605	YhgE/Pip N-terminal domain; Region: pip_yhgE_Nterm; TIGR03061
1128398002606	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
1128398002607	X-X-X-Leu-X-X-Gly heptad repeats; Region: xxxLxxG_by_4; TIGR03057
1128398002608	YhgE/Pip C-terminal domain; Region: pip_yhgE_Cterm; TIGR03062
1128398002609	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
1128398002610	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
1128398002611	active site
1128398002612	HIGH motif; other site
1128398002613	dimer interface [polypeptide binding]; other site
1128398002614	KMSKS motif; other site
1128398002615	NMT1-like family; Region: NMT1_2; pfam13379
1128398002616	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1128398002617	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1128398002618	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
1128398002619	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
1128398002620	active site
1128398002621	NTP binding site [chemical binding]; other site
1128398002622	metal binding triad [ion binding]; metal-binding site
1128398002623	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
1128398002624	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398002625	Zn2+ binding site [ion binding]; other site
1128398002626	Mg2+ binding site [ion binding]; other site
1128398002627	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
1128398002628	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398002629	active site
1128398002630	HIGH motif; other site
1128398002631	nucleotide binding site [chemical binding]; other site
1128398002632	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1128398002633	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
1128398002634	active site
1128398002635	KMSKS motif; other site
1128398002636	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
1128398002637	tRNA binding surface [nucleotide binding]; other site
1128398002638	anticodon binding site; other site
1128398002639	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
1128398002640	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
1128398002641	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398002642	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398002643	Double zinc ribbon; Region: DZR; pfam12773
1128398002644	zinc-ribbon domain; Region: zinc_ribbon_2; pfam13240
1128398002645	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1128398002646	activation loop (A-loop); other site
1128398002647	Uncharacterized conserved protein [Function unknown]; Region: COG3391
1128398002648	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1128398002649	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1128398002650	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398002651	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1128398002652	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1128398002653	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1128398002654	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1128398002655	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1128398002656	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398002657	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1128398002658	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1128398002659	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1128398002660	Domain of unknown function (DUF4364); Region: DUF4364; pfam14277
1128398002661	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1128398002662	Na/Pi-cotransporter; Region: NaPi_cotrn_rel; TIGR00704
1128398002663	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1128398002664	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1128398002665	phosphatidylserine decarboxylase; Provisional; Region: PRK00723
1128398002666	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1128398002667	NodB motif; other site
1128398002668	active site
1128398002669	catalytic site [active]
1128398002670	metal binding site [ion binding]; metal-binding site
1128398002671	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
1128398002672	single-stranded DNA-binding protein; Provisional; Region: PRK05813
1128398002673	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
1128398002674	generic binding surface II; other site
1128398002675	generic binding surface I; other site
1128398002676	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1128398002677	dimer interface [polypeptide binding]; other site
1128398002678	ssDNA binding site [nucleotide binding]; other site
1128398002679	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1128398002680	putative deaminase; Validated; Region: PRK06846
1128398002681	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
1128398002682	active site
1128398002683	CAAX protease self-immunity; Region: Abi; pfam02517
1128398002684	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1128398002685	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1128398002686	putative binding surface; other site
1128398002687	active site
1128398002688	P2 response regulator binding domain; Region: P2; pfam07194
1128398002689	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1128398002690	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398002691	ATP binding site [chemical binding]; other site
1128398002692	Mg2+ binding site [ion binding]; other site
1128398002693	G-X-G motif; other site
1128398002694	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1128398002695	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1128398002696	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1128398002697	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398002698	dimerization interface [polypeptide binding]; other site
1128398002699	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398002700	dimer interface [polypeptide binding]; other site
1128398002701	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1128398002702	putative CheW interface [polypeptide binding]; other site
1128398002703	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1128398002704	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1128398002705	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1128398002706	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1128398002707	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398002708	active site
1128398002709	phosphorylation site [posttranslational modification]
1128398002710	intermolecular recognition site; other site
1128398002711	CheB methylesterase; Region: CheB_methylest; pfam01339
1128398002712	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398002713	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398002714	S-adenosylmethionine binding site [chemical binding]; other site
1128398002715	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1128398002716	DNA-binding site [nucleotide binding]; DNA binding site
1128398002717	RNA-binding motif; other site
1128398002718	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
1128398002719	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
1128398002720	dimerization interface [polypeptide binding]; other site
1128398002721	domain crossover interface; other site
1128398002722	redox-dependent activation switch; other site
1128398002723	YtxC-like family; Region: YtxC; pfam08812
1128398002724	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399
1128398002725	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1128398002726	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398002727	Walker A motif; other site
1128398002728	ATP binding site [chemical binding]; other site
1128398002729	Walker B motif; other site
1128398002730	arginine finger; other site
1128398002731	Peptidase family M41; Region: Peptidase_M41; pfam01434
1128398002732	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
1128398002733	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
1128398002734	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
1128398002735	23S rRNA binding site [nucleotide binding]; other site
1128398002736	L21 binding site [polypeptide binding]; other site
1128398002737	L13 binding site [polypeptide binding]; other site
1128398002738	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
1128398002739	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
1128398002740	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
1128398002741	TrkA-N domain; Region: TrkA_N; pfam02254
1128398002742	TrkA-C domain; Region: TrkA_C; pfam02080
1128398002743	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
1128398002744	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
1128398002745	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1128398002746	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
1128398002747	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
1128398002748	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
1128398002749	dimer interface [polypeptide binding]; other site
1128398002750	motif 1; other site
1128398002751	active site
1128398002752	motif 2; other site
1128398002753	motif 3; other site
1128398002754	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
1128398002755	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
1128398002756	putative tRNA-binding site [nucleotide binding]; other site
1128398002757	B3/4 domain; Region: B3_4; pfam03483
1128398002758	tRNA synthetase B5 domain; Region: B5; smart00874
1128398002759	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
1128398002760	dimer interface [polypeptide binding]; other site
1128398002761	motif 1; other site
1128398002762	motif 3; other site
1128398002763	motif 2; other site
1128398002764	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; smart00896
1128398002765	Cell division protein ZapA; Region: ZapA; pfam05164
1128398002766	Predicted membrane protein [Function unknown]; Region: COG2323
1128398002767	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1128398002768	Peptidase family U32; Region: Peptidase_U32; pfam01136
1128398002769	Collagenase; Region: DUF3656; pfam12392
1128398002770	Peptidase family U32; Region: Peptidase_U32; cl03113
1128398002771	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
1128398002772	MutS domain III; Region: MutS_III; pfam05192
1128398002773	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398002774	Walker A/P-loop; other site
1128398002775	ATP binding site [chemical binding]; other site
1128398002776	Q-loop/lid; other site
1128398002777	ABC transporter signature motif; other site
1128398002778	Walker B; other site
1128398002779	D-loop; other site
1128398002780	H-loop/switch region; other site
1128398002781	Smr domain; Region: Smr; pfam01713
1128398002782	Uncharacterized conserved protein [Function unknown]; Region: COG1683
1128398002783	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398002784	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
1128398002785	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
1128398002786	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
1128398002787	active site
1128398002788	HIGH motif; other site
1128398002789	KMSK motif region; other site
1128398002790	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
1128398002791	tRNA binding surface [nucleotide binding]; other site
1128398002792	anticodon binding site; other site
1128398002793	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
1128398002794	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1128398002795	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398002796	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398002797	DNA binding residues [nucleotide binding]
1128398002798	Putative zinc-finger; Region: zf-HC2; pfam13490
1128398002799	Putative amidase domain; Region: Amidase_6; pfam12671
1128398002800	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
1128398002801	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
1128398002802	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398002803	FeS/SAM binding site; other site
1128398002804	Protein of unknown function (DUF4080); Region: DUF4080; pfam13311
1128398002805	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
1128398002806	binding surface
1128398002807	TPR motif; other site
1128398002808	TPR repeat; Region: TPR_11; pfam13414
1128398002809	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
1128398002810	Zn binding site [ion binding]; other site
1128398002811	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398002812	dimerization interface [polypeptide binding]; other site
1128398002813	putative DNA binding site [nucleotide binding]; other site
1128398002814	putative Zn2+ binding site [ion binding]; other site
1128398002815	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
1128398002816	SdpI/YhfL protein family; Region: SdpI; pfam13630
1128398002817	RNase_H superfamily; Region: RNase_H_2; pfam13482
1128398002818	active site
1128398002819	substrate binding site [chemical binding]; other site
1128398002820	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1128398002821	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
1128398002822	CoA enzyme activase uncharacterized domain (DUF2229); Region: DUF2229; pfam09989
1128398002823	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1128398002824	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
1128398002825	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
1128398002826	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398002827	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1128398002828	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1128398002829	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398002830	catalytic residue [active]
1128398002831	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
1128398002832	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
1128398002833	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
1128398002834	Ligand Binding Site [chemical binding]; other site
1128398002835	Uncharacterized conserved protein [Function unknown]; Region: LemA; COG1704
1128398002836	Repair protein; Region: Repair_PSII; pfam04536
1128398002837	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398002838	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
1128398002839	intersubunit interface [polypeptide binding]; other site
1128398002840	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
1128398002841	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
1128398002842	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
1128398002843	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398002844	ABC-ATPase subunit  interface; other site
1128398002845	dimer interface [polypeptide binding]; other site
1128398002846	putative PBP binding regions; other site
1128398002847	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1128398002848	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398002849	non-specific DNA binding site [nucleotide binding]; other site
1128398002850	salt bridge; other site
1128398002851	sequence-specific DNA binding site [nucleotide binding]; other site
1128398002852	Cupin domain; Region: Cupin_2; pfam07883
1128398002853	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1128398002854	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398002855	Walker A/P-loop; other site
1128398002856	ATP binding site [chemical binding]; other site
1128398002857	Q-loop/lid; other site
1128398002858	ABC transporter signature motif; other site
1128398002859	Walker B; other site
1128398002860	D-loop; other site
1128398002861	H-loop/switch region; other site
1128398002862	TOBE domain; Region: TOBE_2; pfam08402
1128398002863	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
1128398002864	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002865	dimer interface [polypeptide binding]; other site
1128398002866	conserved gate region; other site
1128398002867	putative PBP binding loops; other site
1128398002868	ABC-ATPase subunit interface; other site
1128398002869	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
1128398002870	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398002871	dimer interface [polypeptide binding]; other site
1128398002872	conserved gate region; other site
1128398002873	putative PBP binding loops; other site
1128398002874	ABC-ATPase subunit interface; other site
1128398002875	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
1128398002876	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1128398002877	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1128398002878	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398002879	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398002880	active site
1128398002881	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1128398002882	PspC domain; Region: PspC; pfam04024
1128398002883	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
1128398002884	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
1128398002885	phosphopeptide binding site; other site
1128398002886	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
1128398002887	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1128398002888	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1128398002889	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
1128398002890	oligoendopeptidase F; Region: pepF; TIGR00181
1128398002891	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
1128398002892	active site
1128398002893	Zn binding site [ion binding]; other site
1128398002894	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
1128398002895	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1128398002896	Uncharacterized conserved protein [Function unknown]; Region: COG3339
1128398002897	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398002898	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1128398002899	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1128398002900	active site
1128398002901	aconitate hydratase, mitochondrial; Region: aconitase_mito; TIGR01340
1128398002902	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1128398002903	ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones]; Region: HflB; COG0465
1128398002904	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398002905	Walker A motif; other site
1128398002906	ATP binding site [chemical binding]; other site
1128398002907	Walker B motif; other site
1128398002908	arginine finger; other site
1128398002909	Peptidase family M41; Region: Peptidase_M41; pfam01434
1128398002910	stage V sporulation protein B; Region: spore_V_B; TIGR02900
1128398002911	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1128398002912	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
1128398002913	5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme metabolism]; Region: FolD; COG0190
1128398002914	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
1128398002915	NAD(P) binding pocket [chemical binding]; other site
1128398002916	histidinol-phosphatase; Provisional; Region: PRK05588
1128398002917	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1128398002918	active site
1128398002919	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
1128398002920	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
1128398002921	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1128398002922	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1128398002923	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1128398002924	putative lipid kinase; Reviewed; Region: PRK13337
1128398002925	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
1128398002926	Transcriptional regulators [Transcription]; Region: PurR; COG1609
1128398002927	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
1128398002928	DNA binding site [nucleotide binding]
1128398002929	domain linker motif; other site
1128398002930	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1128398002931	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
1128398002932	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1128398002933	M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659
1128398002934	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
1128398002935	oligomer interface [polypeptide binding]; other site
1128398002936	putative active site [active]
1128398002937	metal binding site [ion binding]; metal-binding site
1128398002938	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398002939	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398002940	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1128398002941	putative dimerization interface [polypeptide binding]; other site
1128398002942	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
1128398002943	DNA polymerase I; Provisional; Region: PRK05755
1128398002944	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
1128398002945	active site
1128398002946	metal binding site 1 [ion binding]; metal-binding site
1128398002947	putative 5' ssDNA interaction site; other site
1128398002948	metal binding site 3; metal-binding site
1128398002949	metal binding site 2 [ion binding]; metal-binding site
1128398002950	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
1128398002951	putative DNA binding site [nucleotide binding]; other site
1128398002952	putative metal binding site [ion binding]; other site
1128398002953	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
1128398002954	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
1128398002955	active site
1128398002956	DNA binding site [nucleotide binding]
1128398002957	catalytic site [active]
1128398002958	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
1128398002959	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
1128398002960	CoA-binding site [chemical binding]; other site
1128398002961	ATP-binding [chemical binding]; other site
1128398002962	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
1128398002963	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
1128398002964	N-acetyl-D-glucosamine binding site [chemical binding]; other site
1128398002965	catalytic residue [active]
1128398002966	nicotinate phosphoribosyltransferase; Reviewed; Region: PRK08662
1128398002967	Phosphoribosyltransferase (PRTase) type II; This family contains two enzymes that play an important role in NAD production by either allowing quinolinic acid (QA) , quinolinate phosphoribosyl transferase (QAPRTase), or nicotinic acid (NA), nicotinate...; Region: PRTase_typeII; cl17275
1128398002968	active site
1128398002969	The substrate-binding component of ABC-type thermophilic oligopeptide-binding protein Hb8-like import systems, contains the type 2 periplasmic binding fold; Region: PBP2_thermophilic_Hb8_like; cd08513
1128398002970	peptide binding site [polypeptide binding]; other site
1128398002971	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
1128398002972	dimer interface [polypeptide binding]; other site
1128398002973	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1128398002974	classical (c) SDRs; Region: SDR_c; cd05233
1128398002975	NAD(P) binding site [chemical binding]; other site
1128398002976	active site
1128398002977	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
1128398002978	SLBB domain; Region: SLBB; pfam10531
1128398002979	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398002980	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
1128398002981	FMN-binding domain; Region: FMN_bind; cl01081
1128398002982	electron transport complex RsxE subunit; Provisional; Region: PRK12405
1128398002983	electron transport complex, RnfABCDGE type, A subunit; Region: rnfA; TIGR01943
1128398002984	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398002985	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1128398002986	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1128398002987	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1128398002988	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398002989	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1128398002990	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
1128398002991	trimer interface [polypeptide binding]; other site
1128398002992	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
1128398002993	Maf-like protein; Region: Maf; pfam02545
1128398002994	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
1128398002995	active site
1128398002996	dimer interface [polypeptide binding]; other site
1128398002997	hypothetical protein; Reviewed; Region: PRK00024
1128398002998	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
1128398002999	MPN+ (JAMM) motif; other site
1128398003000	Zinc-binding site [ion binding]; other site
1128398003001	rod shape-determining protein MreB; Provisional; Region: PRK13927
1128398003002	MreB and similar proteins; Region: MreB_like; cd10225
1128398003003	nucleotide binding site [chemical binding]; other site
1128398003004	Mg binding site [ion binding]; other site
1128398003005	putative protofilament interaction site [polypeptide binding]; other site
1128398003006	RodZ interaction site [polypeptide binding]; other site
1128398003007	rod shape-determining protein MreC; Provisional; Region: PRK13922
1128398003008	rod shape-determining protein MreC; Region: MreC; pfam04085
1128398003009	rod shape-determining protein MreD; Region: shape_MreD; TIGR03426
1128398003010	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1128398003011	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1128398003012	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1128398003013	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
1128398003014	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
1128398003015	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
1128398003016	Protein of unknown function DUF45; Region: DUF45; pfam01863
1128398003017	DNA polymerase IV; Provisional; Region: PRK14133
1128398003018	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
1128398003019	active site
1128398003020	DNA binding site [nucleotide binding]
1128398003021	Uncharacterized BCR, COG1649; Region: DUF187; pfam02638
1128398003022	Glyco_18 domain; Region: Glyco_18; smart00636
1128398003023	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1128398003024	active site
1128398003025	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398003026	ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism]; Region: ProV; COG4175
1128398003027	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
1128398003028	Walker A/P-loop; other site
1128398003029	ATP binding site [chemical binding]; other site
1128398003030	Q-loop/lid; other site
1128398003031	ABC transporter signature motif; other site
1128398003032	Walker B; other site
1128398003033	D-loop; other site
1128398003034	H-loop/switch region; other site
1128398003035	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1128398003036	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003037	dimer interface [polypeptide binding]; other site
1128398003038	conserved gate region; other site
1128398003039	putative PBP binding loops; other site
1128398003040	ABC-ATPase subunit interface; other site
1128398003041	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1128398003042	ABC-type proline/glycine betaine transport systems, periplasmic components [Amino acid transport and metabolism]; Region: ProX; cl17891
1128398003043	Substrate binding domain of ABC-type glycine betaine transport system; Region: OpuAC; pfam04069
1128398003044	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1128398003045	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
1128398003046	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
1128398003047	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
1128398003048	Deacetylases, including yeast histone deacetylase and acetoin utilization protein [Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism]; Region: AcuC; COG0123
1128398003049	Histone deacetylases and histone-like deacetylases, classII; Region: HDAC_classII; cd09992
1128398003050	active site
1128398003051	Zn binding site [ion binding]; other site
1128398003052	4-alpha-glucanotransferase; Provisional; Region: PRK14508
1128398003053	hypothetical protein; Provisional; Region: PRK03881
1128398003054	The N-terminal domain, an extradiol dioxygenase class III subunit B-like domain, of unknown proteins containing a C-terminal AMMECR1 domain; Region: ED_3B_N_AMMECR1; cd07951
1128398003055	AMMECR1; Region: AMMECR1; pfam01871
1128398003056	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1128398003057	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398003058	non-specific DNA binding site [nucleotide binding]; other site
1128398003059	salt bridge; other site
1128398003060	sequence-specific DNA binding site [nucleotide binding]; other site
1128398003061	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398003062	non-specific DNA binding site [nucleotide binding]; other site
1128398003063	salt bridge; other site
1128398003064	sequence-specific DNA binding site [nucleotide binding]; other site
1128398003065	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1128398003066	anti sigma factor interaction site; other site
1128398003067	regulatory phosphorylation site [posttranslational modification]; other site
1128398003068	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
1128398003069	anti-sigma F factor; Provisional; Region: PRK03660
1128398003070	sporulation sigma factor SigF; Validated; Region: PRK05572
1128398003071	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398003072	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1128398003073	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398003074	DNA binding residues [nucleotide binding]
1128398003075	stage V sporulation protein AC; Region: spore_V_AC; TIGR02838
1128398003076	stage V sporulation protein AD; Validated; Region: PRK08304
1128398003077	stage V sporulation protein AD; Provisional; Region: PRK12404
1128398003078	stage V sporulation protein AE; Region: spore_V_AE; TIGR02839
1128398003079	glycosyltransferase; Provisional; Region: PRK13481
1128398003080	Transglycosylase; Region: Transgly; pfam00912
1128398003081	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1128398003082	Sporulation protein YunB (Spo_YunB); Region: Spore_YunB; cl09783
1128398003083	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
1128398003084	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
1128398003085	HflX GTPase family; Region: HflX; cd01878
1128398003086	G1 box; other site
1128398003087	GTP/Mg2+ binding site [chemical binding]; other site
1128398003088	Switch I region; other site
1128398003089	G2 box; other site
1128398003090	G3 box; other site
1128398003091	Switch II region; other site
1128398003092	G4 box; other site
1128398003093	G5 box; other site
1128398003094	Protein of unknown function (DUF3189); Region: DUF3189; pfam11385
1128398003095	Uncharacterized conserved protein [Function unknown]; Region: COG1739
1128398003096	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
1128398003097	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
1128398003098	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398003099	Walker A/P-loop; other site
1128398003100	ATP binding site [chemical binding]; other site
1128398003101	Q-loop/lid; other site
1128398003102	ABC transporter signature motif; other site
1128398003103	Walker B; other site
1128398003104	D-loop; other site
1128398003105	H-loop/switch region; other site
1128398003106	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1128398003107	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
1128398003108	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
1128398003109	NAD synthetase; Provisional; Region: PRK13980
1128398003110	homodimer interface [polypeptide binding]; other site
1128398003111	NAD binding pocket [chemical binding]; other site
1128398003112	ATP binding pocket [chemical binding]; other site
1128398003113	Mg binding site [ion binding]; other site
1128398003114	active-site loop [active]
1128398003115	hypothetical protein; Validated; Region: PRK00110
1128398003116	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398003117	dimerization interface [polypeptide binding]; other site
1128398003118	putative DNA binding site [nucleotide binding]; other site
1128398003119	putative Zn2+ binding site [ion binding]; other site
1128398003120	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398003121	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
1128398003122	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
1128398003123	The band 7 domain of flotillin (reggie) like proteins. This group contains proteins similar to stomatin, prohibitin, flotillin, HlfK/C and podicin.  Many of these band 7 domain-containing proteins are lipid raft-associated.  Individual proteins of this...; Region: Band_7; cl02525
1128398003124	ferredoxin; Validated; Region: PRK07118
1128398003125	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1128398003126	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398003127	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
1128398003128	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
1128398003129	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398003130	Walker A/P-loop; other site
1128398003131	ATP binding site [chemical binding]; other site
1128398003132	Q-loop/lid; other site
1128398003133	ABC transporter signature motif; other site
1128398003134	Walker B; other site
1128398003135	D-loop; other site
1128398003136	H-loop/switch region; other site
1128398003137	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
1128398003138	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003139	dimer interface [polypeptide binding]; other site
1128398003140	conserved gate region; other site
1128398003141	putative PBP binding loops; other site
1128398003142	ABC-ATPase subunit interface; other site
1128398003143	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1128398003144	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1128398003145	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
1128398003146	active site
1128398003147	putative DNA-binding cleft [nucleotide binding]; other site
1128398003148	dimer interface [polypeptide binding]; other site
1128398003149	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
1128398003150	RuvA N terminal domain; Region: RuvA_N; pfam01330
1128398003151	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
1128398003152	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
1128398003153	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398003154	Walker A motif; other site
1128398003155	ATP binding site [chemical binding]; other site
1128398003156	Walker B motif; other site
1128398003157	arginine finger; other site
1128398003158	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
1128398003159	Stage II sporulation protein; Region: SpoIID; pfam08486
1128398003160	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
1128398003161	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
1128398003162	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Region: queA; TIGR00113
1128398003163	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
1128398003164	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
1128398003165	Preprotein translocase subunit; Region: YajC; pfam02699
1128398003166	radical SAM protein, TIGR01212 family; Region: TIGR01212
1128398003167	Putative methyltransferase; Region: Methyltransf_4; cl17290
1128398003168	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
1128398003169	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398003170	S-adenosylmethionine binding site [chemical binding]; other site
1128398003171	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
1128398003172	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1128398003173	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398003174	RNA binding surface [nucleotide binding]; other site
1128398003175	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
1128398003176	active site
1128398003177	uracil binding [chemical binding]; other site
1128398003178	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
1128398003179	CDP-diacylglycerol--serine O-phosphatidyltransferase; Region: pssA; TIGR00473
1128398003180	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1128398003181	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cl09940
1128398003182	RNA binding surface [nucleotide binding]; other site
1128398003183	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1128398003184	active site
1128398003185	FOG: CBS domain [General function prediction only]; Region: COG0517
1128398003186	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_9; cd04622
1128398003187	Sporulation and spore germination; Region: Germane; pfam10646
1128398003188	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
1128398003189	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1128398003190	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
1128398003191	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398003192	catalytic residue [active]
1128398003193	endonuclease IV; Provisional; Region: PRK01060
1128398003194	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
1128398003195	AP (apurinic/apyrimidinic) site pocket; other site
1128398003196	DNA interaction; other site
1128398003197	Metal-binding active site; metal-binding site
1128398003198	epoxyqueuosine reductase; Region: TIGR00276
1128398003199	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
1128398003200	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398003201	Protein of unknown function (DUF503); Region: DUF503; pfam04456
1128398003202	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
1128398003203	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
1128398003204	minor groove reading motif; other site
1128398003205	helix-hairpin-helix signature motif; other site
1128398003206	substrate binding pocket [chemical binding]; other site
1128398003207	active site
1128398003208	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
1128398003209	Cell division ATPase FtsA [Cell division and chromosome partitioning]; Region: ftsA; COG0849
1128398003210	Cell division protein FtsA; Region: FtsA; smart00842
1128398003211	Cell division protein FtsA; Region: FtsA; pfam14450
1128398003212	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
1128398003213	VanW like protein; Region: VanW; pfam04294
1128398003214	Uncharacterized protein conserved in bacteria (DUF2225); Region: DUF2225; pfam09986
1128398003215	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1655
1128398003216	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1128398003217	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1128398003218	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1128398003219	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398003220	catalytic loop [active]
1128398003221	iron binding site [ion binding]; other site
1128398003222	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1128398003223	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1128398003224	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1128398003225	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1128398003226	PGAP1-like protein; Region: PGAP1; pfam07819
1128398003227	Lecithin:cholesterol acyltransferase; Region: LACT; pfam02450
1128398003228	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
1128398003229	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
1128398003230	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1128398003231	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
1128398003232	PhoU domain; Region: PhoU; pfam01895
1128398003233	PhoU domain; Region: PhoU; pfam01895
1128398003234	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
1128398003235	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1128398003236	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1128398003237	glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729
1128398003238	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
1128398003239	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1128398003240	Phosphoglycerate kinase; Region: PGK; pfam00162
1128398003241	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
1128398003242	substrate binding site [chemical binding]; other site
1128398003243	hinge regions; other site
1128398003244	ADP binding site [chemical binding]; other site
1128398003245	catalytic site [active]
1128398003246	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
1128398003247	triosephosphate isomerase; Provisional; Region: PRK14565
1128398003248	substrate binding site [chemical binding]; other site
1128398003249	dimer interface [polypeptide binding]; other site
1128398003250	catalytic triad [active]
1128398003251	Phosphoglyceromutase [Carbohydrate transport and metabolism]; Region: GpmI; COG0696
1128398003252	phosphoglyceromutase; Provisional; Region: PRK05434
1128398003253	enolase; Provisional; Region: eno; PRK00077
1128398003254	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
1128398003255	dimer interface [polypeptide binding]; other site
1128398003256	metal binding site [ion binding]; metal-binding site
1128398003257	substrate binding pocket [chemical binding]; other site
1128398003258	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
1128398003259	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
1128398003260	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
1128398003261	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398003262	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398003263	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
1128398003264	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
1128398003265	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1128398003266	ribonuclease R; Region: RNase_R; TIGR02063
1128398003267	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
1128398003268	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1128398003269	RNB domain; Region: RNB; pfam00773
1128398003270	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
1128398003271	RNA binding site [nucleotide binding]; other site
1128398003272	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
1128398003273	SmpB-tmRNA interface; other site
1128398003274	Predicted nucleotide-binding protein containing TIR-like domain; Region: TIR-like; cl17861
1128398003275	FRG domain; Region: FRG; pfam08867
1128398003276	Protein of unknown function (DUF3955); Region: DUF3955; pfam13127
1128398003277	superantigen-like protein; Reviewed; Region: PRK13042
1128398003278	Uncharacterized conserved protein, contains double-stranded beta-helix domain [Function unknown]; Region: COG1917
1128398003279	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1128398003280	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398003281	Predicted transcriptional regulators [Transcription]; Region: COG1733
1128398003282	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1128398003283	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
1128398003284	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
1128398003285	dimer interface [polypeptide binding]; other site
1128398003286	active site
1128398003287	metal binding site [ion binding]; metal-binding site
1128398003288	glutathione binding site [chemical binding]; other site
1128398003289	PAS domain S-box; Region: sensory_box; TIGR00229
1128398003290	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398003291	putative active site [active]
1128398003292	heme pocket [chemical binding]; other site
1128398003293	PAS domain S-box; Region: sensory_box; TIGR00229
1128398003294	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398003295	putative active site [active]
1128398003296	heme pocket [chemical binding]; other site
1128398003297	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398003298	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398003299	dimer interface [polypeptide binding]; other site
1128398003300	phosphorylation site [posttranslational modification]
1128398003301	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398003302	ATP binding site [chemical binding]; other site
1128398003303	Mg2+ binding site [ion binding]; other site
1128398003304	G-X-G motif; other site
1128398003305	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
1128398003306	active site
1128398003307	putative catalytic site [active]
1128398003308	DNA binding site [nucleotide binding]
1128398003309	putative phosphate binding site [ion binding]; other site
1128398003310	metal binding site A [ion binding]; metal-binding site
1128398003311	AP binding site [nucleotide binding]; other site
1128398003312	metal binding site B [ion binding]; metal-binding site
1128398003313	FMN-binding domain; Region: FMN_bind; cl01081
1128398003314	ferredoxin-type protein, NapH/MauN family; Region: napH_; TIGR02163
1128398003315	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1128398003316	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1128398003317	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398003318	FMN-binding domain; Region: FMN_bind; cl01081
1128398003319	MoxR-like ATPases [General function prediction only]; Region: COG0714
1128398003320	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398003321	Walker A motif; other site
1128398003322	ATP binding site [chemical binding]; other site
1128398003323	Walker B motif; other site
1128398003324	arginine finger; other site
1128398003325	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2425
1128398003326	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
1128398003327	metal ion-dependent adhesion site (MIDAS); other site
1128398003328	YcxB-like protein; Region: YcxB; pfam14317
1128398003329	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
1128398003330	Haemolysin-III related; Region: HlyIII; cl03831
1128398003331	EcsC protein family; Region: EcsC; pfam12787
1128398003332	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
1128398003333	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1128398003334	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398003335	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1128398003336	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
1128398003337	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1128398003338	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1128398003339	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1128398003340	Catalytic site [active]
1128398003341	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
1128398003342	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1128398003343	catalytic residue [active]
1128398003344	putative FPP diphosphate  binding site; other site
1128398003345	putative FPP binding hydrophobic cleft; other site
1128398003346	dimer interface [polypeptide binding]; other site
1128398003347	putative IPP diphosphate binding site; other site
1128398003348	short chain dehydrogenase; Provisional; Region: PRK06701
1128398003349	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1128398003350	NAD binding site [chemical binding]; other site
1128398003351	metal binding site [ion binding]; metal-binding site
1128398003352	active site
1128398003353	37-kD nucleoid-associated bacterial protein; Region: NA37; cl15473
1128398003354	Ribosomal RNA adenine dimethylase; Region: RrnaAD; pfam00398
1128398003355	Ribosomal RNA adenine dimethylases; Region: rADc; smart00650
1128398003356	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
1128398003357	nucleotide binding site [chemical binding]; other site
1128398003358	Stress responsive A/B Barrel Domain; Region: Dabb; smart00886
1128398003359	DNA topoisomerase III; Provisional; Region: PRK07726
1128398003360	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1128398003361	active site
1128398003362	putative interdomain interaction site [polypeptide binding]; other site
1128398003363	putative metal-binding site [ion binding]; other site
1128398003364	putative nucleotide binding site [chemical binding]; other site
1128398003365	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1128398003366	domain I; other site
1128398003367	DNA binding groove [nucleotide binding]
1128398003368	phosphate binding site [ion binding]; other site
1128398003369	domain II; other site
1128398003370	domain III; other site
1128398003371	nucleotide binding site [chemical binding]; other site
1128398003372	catalytic site [active]
1128398003373	domain IV; other site
1128398003374	DNA topoisomerase III, bacteria and conjugative plasmid; Region: topB; TIGR01056
1128398003375	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
1128398003376	active site
1128398003377	putative interdomain interaction site [polypeptide binding]; other site
1128398003378	putative metal-binding site [ion binding]; other site
1128398003379	putative nucleotide binding site [chemical binding]; other site
1128398003380	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cl11986
1128398003381	domain I; other site
1128398003382	DNA binding groove [nucleotide binding]
1128398003383	phosphate binding site [ion binding]; other site
1128398003384	domain II; other site
1128398003385	domain III; other site
1128398003386	nucleotide binding site [chemical binding]; other site
1128398003387	catalytic site [active]
1128398003388	domain IV; other site
1128398003389	Uncharacterized BCR, YaiI/YqxD family COG1671; Region: DUF188; cl00727
1128398003390	Predicted ATPase [General function prediction only]; Region: COG3910
1128398003391	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398003392	ATP-binding cassette domain of non-transporter proteins; Region: ABC_Class2; cd03227
1128398003393	Walker A/P-loop; other site
1128398003394	Walker A/P-loop; other site
1128398003395	ATP binding site [chemical binding]; other site
1128398003396	ATP binding site [chemical binding]; other site
1128398003397	Q-loop/lid; other site
1128398003398	ABC transporter signature motif; other site
1128398003399	Walker B; other site
1128398003400	D-loop; other site
1128398003401	H-loop/switch region; other site
1128398003402	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
1128398003403	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_16; cd08502
1128398003404	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
1128398003405	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003406	putative PBP binding loops; other site
1128398003407	dimer interface [polypeptide binding]; other site
1128398003408	ABC-ATPase subunit interface; other site
1128398003409	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
1128398003410	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003411	dimer interface [polypeptide binding]; other site
1128398003412	conserved gate region; other site
1128398003413	putative PBP binding loops; other site
1128398003414	ABC-ATPase subunit interface; other site
1128398003415	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
1128398003416	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1128398003417	Walker A/P-loop; other site
1128398003418	ATP binding site [chemical binding]; other site
1128398003419	Q-loop/lid; other site
1128398003420	ABC transporter signature motif; other site
1128398003421	Walker B; other site
1128398003422	D-loop; other site
1128398003423	H-loop/switch region; other site
1128398003424	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1128398003425	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
1128398003426	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
1128398003427	Walker A/P-loop; other site
1128398003428	ATP binding site [chemical binding]; other site
1128398003429	Q-loop/lid; other site
1128398003430	ABC transporter signature motif; other site
1128398003431	Walker B; other site
1128398003432	D-loop; other site
1128398003433	H-loop/switch region; other site
1128398003434	oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain; Region: oligo_HPY; TIGR01727
1128398003435	Uncharacterized ArCR, COG2043; Region: DUF169; pfam02596
1128398003436	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1128398003437	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1128398003438	Uncharacterized ArCR, COG2043; Region: DUF169; pfam02596
1128398003439	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1128398003440	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1128398003441	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
1128398003442	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1128398003443	Walker A/P-loop; other site
1128398003444	ATP binding site [chemical binding]; other site
1128398003445	Q-loop/lid; other site
1128398003446	ABC transporter signature motif; other site
1128398003447	Walker B; other site
1128398003448	D-loop; other site
1128398003449	H-loop/switch region; other site
1128398003450	NIL domain; Region: NIL; pfam09383
1128398003451	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003452	dimer interface [polypeptide binding]; other site
1128398003453	conserved gate region; other site
1128398003454	ABC-ATPase subunit interface; other site
1128398003455	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1128398003456	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1128398003457	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
1128398003458	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1128398003459	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
1128398003460	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1128398003461	NLPA lipoprotein; Region: Lipoprotein_9; cl17547
1128398003462	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398003463	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398003464	Walker A/P-loop; other site
1128398003465	ATP binding site [chemical binding]; other site
1128398003466	Q-loop/lid; other site
1128398003467	ABC transporter signature motif; other site
1128398003468	Walker B; other site
1128398003469	D-loop; other site
1128398003470	H-loop/switch region; other site
1128398003471	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398003472	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003473	dimer interface [polypeptide binding]; other site
1128398003474	conserved gate region; other site
1128398003475	putative PBP binding loops; other site
1128398003476	ABC-ATPase subunit interface; other site
1128398003477	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
1128398003478	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cl17432
1128398003479	NMT1/THI5 like; Region: NMT1; pfam09084
1128398003480	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1128398003481	The URO-D _like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases. Uroporphyrinogen decarboxylase (URO-D) decarboxylates the four...; Region: URO-D_like; cd03465
1128398003482	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
1128398003483	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
1128398003484	B12 binding site [chemical binding]; other site
1128398003485	cobalt ligand [ion binding]; other site
1128398003486	methylcobalamin:coenzyme M methyltransferase; Validated; Region: PRK06252
1128398003487	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
1128398003488	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
1128398003489	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398003490	catalytic loop [active]
1128398003491	iron binding site [ion binding]; other site
1128398003492	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
1128398003493	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398003494	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
1128398003495	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
1128398003496	Predicted permeases [General function prediction only]; Region: COG0679
1128398003497	Predicted permeases [General function prediction only]; Region: COG0679
1128398003498	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
1128398003499	thiamine phosphate binding site [chemical binding]; other site
1128398003500	active site
1128398003501	pyrophosphate binding site [ion binding]; other site
1128398003502	thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644
1128398003503	E1_ThiF_like. Member of superfamily of activating enzymes (E1) of the ubiquitin-like proteins. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like substrate, on...; Region: E1_ThiF_like; cd01487
1128398003504	putative ATP binding site [chemical binding]; other site
1128398003505	putative substrate interface [chemical binding]; other site
1128398003506	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
1128398003507	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398003508	FeS/SAM binding site; other site
1128398003509	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
1128398003510	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
1128398003511	ThiS interaction site; other site
1128398003512	putative active site [active]
1128398003513	tetramer interface [polypeptide binding]; other site
1128398003514	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
1128398003515	thiS-thiF/thiG interaction site; other site
1128398003516	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1128398003517	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1128398003518	homodimer interface [polypeptide binding]; other site
1128398003519	substrate-cofactor binding pocket; other site
1128398003520	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398003521	catalytic residue [active]
1128398003522	Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities [Amino acid transport and metabolism]; Region: MalY; COG1168
1128398003523	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398003524	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398003525	homodimer interface [polypeptide binding]; other site
1128398003526	catalytic residue [active]
1128398003527	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
1128398003528	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
1128398003529	catalytic triad [active]
1128398003530	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1128398003531	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1128398003532	putative ligand binding site [chemical binding]; other site
1128398003533	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1128398003534	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1128398003535	TM-ABC transporter signature motif; other site
1128398003536	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1128398003537	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1128398003538	TM-ABC transporter signature motif; other site
1128398003539	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1128398003540	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1128398003541	Walker A/P-loop; other site
1128398003542	ATP binding site [chemical binding]; other site
1128398003543	Q-loop/lid; other site
1128398003544	ABC transporter signature motif; other site
1128398003545	Walker B; other site
1128398003546	D-loop; other site
1128398003547	H-loop/switch region; other site
1128398003548	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1128398003549	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1128398003550	Walker A/P-loop; other site
1128398003551	ATP binding site [chemical binding]; other site
1128398003552	Q-loop/lid; other site
1128398003553	ABC transporter signature motif; other site
1128398003554	Walker B; other site
1128398003555	D-loop; other site
1128398003556	H-loop/switch region; other site
1128398003557	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1128398003558	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1128398003559	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1128398003560	dihydrodipicolinate reductase; Provisional; Region: PRK00048
1128398003561	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1128398003562	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
1128398003563	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
1128398003564	dihydrodipicolinate synthase; Region: dapA; TIGR00674
1128398003565	dimer interface [polypeptide binding]; other site
1128398003566	active site
1128398003567	catalytic residue [active]
1128398003568	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
1128398003569	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1128398003570	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
1128398003571	aspartate kinase; Reviewed; Region: PRK06635
1128398003572	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
1128398003573	putative nucleotide binding site [chemical binding]; other site
1128398003574	putative catalytic residues [active]
1128398003575	putative Mg ion binding site [ion binding]; other site
1128398003576	putative aspartate binding site [chemical binding]; other site
1128398003577	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related proteins; Region: ACT_AKii-LysC-BS-like_1; cd04913
1128398003578	putative allosteric regulatory site; other site
1128398003579	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1128398003580	diaminopimelate decarboxylase; Region: lysA; TIGR01048
1128398003581	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
1128398003582	active site
1128398003583	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1128398003584	substrate binding site [chemical binding]; other site
1128398003585	catalytic residues [active]
1128398003586	dimer interface [polypeptide binding]; other site
1128398003587	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
1128398003588	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1128398003589	Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism]; Region: LeuA; COG0119
1128398003590	Clostridium kluyveri Re-citrate synthase and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_Re_CS; cd07947
1128398003591	active site
1128398003592	catalytic residues [active]
1128398003593	metal binding site [ion binding]; metal-binding site
1128398003594	aconitate hydratase; Validated; Region: PRK07229
1128398003595	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Bact; cd01585
1128398003596	substrate binding site [chemical binding]; other site
1128398003597	ligand binding site [chemical binding]; other site
1128398003598	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
1128398003599	hypothetical protein; Provisional; Region: PRK14812
1128398003600	substrate binding site [chemical binding]; other site
1128398003601	gamma-glutamyl kinase; Provisional; Region: PRK05429
1128398003602	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
1128398003603	nucleotide binding site [chemical binding]; other site
1128398003604	homotetrameric interface [polypeptide binding]; other site
1128398003605	putative phosphate binding site [ion binding]; other site
1128398003606	putative allosteric binding site; other site
1128398003607	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
1128398003608	gamma-glutamyl phosphate reductase; Region: proA; TIGR00407
1128398003609	putative catalytic cysteine [active]
1128398003610	pyruvate carboxylase; Reviewed; Region: PRK12999
1128398003611	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1128398003612	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1128398003613	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1128398003614	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
1128398003615	active site
1128398003616	catalytic residues [active]
1128398003617	metal binding site [ion binding]; metal-binding site
1128398003618	homodimer binding site [polypeptide binding]; other site
1128398003619	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1128398003620	carboxyltransferase (CT) interaction site; other site
1128398003621	biotinylation site [posttranslational modification]; other site
1128398003622	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398003623	active site
1128398003624	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1128398003625	synthetase active site [active]
1128398003626	NTP binding site [chemical binding]; other site
1128398003627	metal binding site [ion binding]; metal-binding site
1128398003628	YibE/F-like protein; Region: YibE_F; pfam07907
1128398003629	EDD domain protein, DegV family; Region: DegV; TIGR00762
1128398003630	Uncharacterized protein, DegV family COG1307; Region: DegV; pfam02645
1128398003631	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1128398003632	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398003633	metal binding site [ion binding]; metal-binding site
1128398003634	active site
1128398003635	I-site; other site
1128398003636	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1128398003637	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1128398003638	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1128398003639	Ligand Binding Site [chemical binding]; other site
1128398003640	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1128398003641	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398003642	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1128398003643	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1128398003644	Hexamer interface [polypeptide binding]; other site
1128398003645	Hexagonal pore residue; other site
1128398003646	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398003647	Coenzyme A binding pocket [chemical binding]; other site
1128398003648	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1128398003649	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398003650	Coenzyme A binding pocket [chemical binding]; other site
1128398003651	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1128398003652	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1128398003653	trimer interface [polypeptide binding]; other site
1128398003654	active site
1128398003655	substrate binding site [chemical binding]; other site
1128398003656	CoA binding site [chemical binding]; other site
1128398003657	2'-5' RNA ligase; Region: 2_5_ligase; TIGR02258
1128398003658	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1128398003659	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
1128398003660	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398003661	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398003662	active site
1128398003663	phosphorylation site [posttranslational modification]
1128398003664	intermolecular recognition site; other site
1128398003665	dimerization interface [polypeptide binding]; other site
1128398003666	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398003667	DNA binding site [nucleotide binding]
1128398003668	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398003669	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398003670	dimerization interface [polypeptide binding]; other site
1128398003671	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398003672	dimer interface [polypeptide binding]; other site
1128398003673	phosphorylation site [posttranslational modification]
1128398003674	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398003675	ATP binding site [chemical binding]; other site
1128398003676	Mg2+ binding site [ion binding]; other site
1128398003677	G-X-G motif; other site
1128398003678	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398003679	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398003680	Walker A/P-loop; other site
1128398003681	ATP binding site [chemical binding]; other site
1128398003682	Q-loop/lid; other site
1128398003683	ABC transporter signature motif; other site
1128398003684	Walker B; other site
1128398003685	D-loop; other site
1128398003686	H-loop/switch region; other site
1128398003687	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398003688	FtsX-like permease family; Region: FtsX; pfam02687
1128398003689	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398003690	FtsX-like permease family; Region: FtsX; pfam02687
1128398003691	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1128398003692	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398003693	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398003694	DNA binding residues [nucleotide binding]
1128398003695	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1128398003696	2-isopropylmalate synthase; Validated; Region: PRK00915
1128398003697	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
1128398003698	active site
1128398003699	catalytic residues [active]
1128398003700	metal binding site [ion binding]; metal-binding site
1128398003701	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; pfam08502
1128398003702	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1128398003703	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1128398003704	PYR/PP interface [polypeptide binding]; other site
1128398003705	dimer interface [polypeptide binding]; other site
1128398003706	TPP binding site [chemical binding]; other site
1128398003707	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1128398003708	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1128398003709	TPP-binding site [chemical binding]; other site
1128398003710	dimer interface [polypeptide binding]; other site
1128398003711	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
1128398003712	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
1128398003713	putative valine binding site [chemical binding]; other site
1128398003714	dimer interface [polypeptide binding]; other site
1128398003715	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
1128398003716	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
1128398003717	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
1128398003718	prephenate dehydrogenase; Validated; Region: PRK08507
1128398003719	Prephenate dehydrogenase [Amino acid transport and metabolism]; Region: TyrA; COG0287
1128398003720	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
1128398003721	active site
1128398003722	dimer interface [polypeptide binding]; other site
1128398003723	metal binding site [ion binding]; metal-binding site
1128398003724	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
1128398003725	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
1128398003726	hinge; other site
1128398003727	active site
1128398003728	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
1128398003729	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
1128398003730	Tetramer interface [polypeptide binding]; other site
1128398003731	active site
1128398003732	FMN-binding site [chemical binding]; other site
1128398003733	monofunctional chorismate mutase, gram positive-type, clade 2; Region: CM_mono_grmpos; TIGR01805
1128398003734	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
1128398003735	Prephenate dehydratase; Region: PDT; pfam00800
1128398003736	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
1128398003737	putative L-Phe binding site [chemical binding]; other site
1128398003738	shikimate kinase; Reviewed; Region: aroK; PRK00131
1128398003739	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
1128398003740	ADP binding site [chemical binding]; other site
1128398003741	magnesium binding site [ion binding]; other site
1128398003742	putative shikimate binding site; other site
1128398003743	Dehydroquinase class II; Region: DHquinase_II; pfam01220
1128398003744	Dehydroquinase (DHQase), type II. Dehydroquinase (or 3-dehydroquinate dehydratase) catalyzes the reversible dehydration of 3-dehydroquinate to form 3-dehydroshikimate. This reaction is part of two metabolic pathways: the biosynthetic shikimate pathway...; Region: DHQase_II; cd00466
1128398003745	trimer interface [polypeptide binding]; other site
1128398003746	active site
1128398003747	dimer interface [polypeptide binding]; other site
1128398003748	Homoserine O-succinyltransferase; Region: HTS; pfam04204
1128398003749	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
1128398003750	proposed active site lysine [active]
1128398003751	conserved cys residue [active]
1128398003752	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
1128398003753	active site
1128398003754	DNA binding site [nucleotide binding]
1128398003755	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
1128398003756	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
1128398003757	3-isopropylmalate dehydratase small subunit; Reviewed; Region: leuD; PRK00439
1128398003758	substrate binding site [chemical binding]; other site
1128398003759	3-isopropylmalate dehydratase large subunit; Reviewed; Region: PRK00402
1128398003760	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
1128398003761	substrate binding site [chemical binding]; other site
1128398003762	ligand binding site [chemical binding]; other site
1128398003763	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
1128398003764	tartrate dehydrogenase; Region: TTC; TIGR02089
1128398003765	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398003766	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398003767	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1128398003768	dimerization interface [polypeptide binding]; other site
1128398003769	putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional; Region: PRK12344
1128398003770	Desulfobacterium autotrophicum LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA3; cd07941
1128398003771	active site
1128398003772	catalytic residues [active]
1128398003773	metal binding site [ion binding]; metal-binding site
1128398003774	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
1128398003775	ketol-acid reductoisomerase; Provisional; Region: PRK05479
1128398003776	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
1128398003777	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
1128398003778	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
1128398003779	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
1128398003780	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
1128398003781	PYR/PP interface [polypeptide binding]; other site
1128398003782	dimer interface [polypeptide binding]; other site
1128398003783	TPP binding site [chemical binding]; other site
1128398003784	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
1128398003785	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
1128398003786	TPP-binding site [chemical binding]; other site
1128398003787	dimer interface [polypeptide binding]; other site
1128398003788	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
1128398003789	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398003790	S-adenosylmethionine binding site [chemical binding]; other site
1128398003791	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
1128398003792	RNA/DNA hybrid binding site [nucleotide binding]; other site
1128398003793	active site
1128398003794	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1128398003795	DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]; Region: DnaJ; COG0484
1128398003796	HSP70 interaction site [polypeptide binding]; other site
1128398003797	Tetratricopeptide repeat; Region: TPR_16; pfam13432
1128398003798	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1128398003799	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398003800	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
1128398003801	Protein of unknown function (DUF3006); Region: DUF3006; pfam11213
1128398003802	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398003803	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1128398003804	substrate binding pocket [chemical binding]; other site
1128398003805	membrane-bound complex binding site; other site
1128398003806	hinge residues; other site
1128398003807	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1128398003808	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003809	dimer interface [polypeptide binding]; other site
1128398003810	conserved gate region; other site
1128398003811	putative PBP binding loops; other site
1128398003812	ABC-ATPase subunit interface; other site
1128398003813	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1128398003814	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1128398003815	Walker A/P-loop; other site
1128398003816	ATP binding site [chemical binding]; other site
1128398003817	Q-loop/lid; other site
1128398003818	ABC transporter signature motif; other site
1128398003819	Walker B; other site
1128398003820	D-loop; other site
1128398003821	H-loop/switch region; other site
1128398003822	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
1128398003823	dimer interface [polypeptide binding]; other site
1128398003824	active site
1128398003825	YceG-like family; Region: YceG; pfam02618
1128398003826	Protein of unknown function (DUF1461); Region: DUF1461; cl01862
1128398003827	Restriction endonuclease; Region: Mrr_cat; pfam04471
1128398003828	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
1128398003829	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
1128398003830	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
1128398003831	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1128398003832	Propanediol utilisation protein PduL; Region: PduL; pfam06130
1128398003833	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
1128398003834	intersubunit interface [polypeptide binding]; other site
1128398003835	active site
1128398003836	catalytic residue [active]
1128398003837	TSCPD domain; Region: TSCPD; cl14834
1128398003838	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
1128398003839	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398003840	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398003841	metal binding site [ion binding]; metal-binding site
1128398003842	active site
1128398003843	I-site; other site
1128398003844	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
1128398003845	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398003846	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398003847	ABC transporter; Region: ABC_tran_2; pfam12848
1128398003848	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398003849	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398003850	Coenzyme A binding pocket [chemical binding]; other site
1128398003851	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1128398003852	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398003853	non-specific DNA binding site [nucleotide binding]; other site
1128398003854	salt bridge; other site
1128398003855	sequence-specific DNA binding site [nucleotide binding]; other site
1128398003856	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398003857	non-specific DNA binding site [nucleotide binding]; other site
1128398003858	salt bridge; other site
1128398003859	sequence-specific DNA binding site [nucleotide binding]; other site
1128398003860	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1128398003861	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1128398003862	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1128398003863	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1128398003864	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
1128398003865	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
1128398003866	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398003867	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
1128398003868	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
1128398003869	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
1128398003870	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
1128398003871	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1128398003872	Tfp pilus assembly protein, pilus retraction ATPase PilT [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilT; COG2805
1128398003873	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1128398003874	Walker A motif; other site
1128398003875	ATP binding site [chemical binding]; other site
1128398003876	Walker B motif; other site
1128398003877	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
1128398003878	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
1128398003879	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1128398003880	Walker A motif; other site
1128398003881	ATP binding site [chemical binding]; other site
1128398003882	Walker B motif; other site
1128398003883	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
1128398003884	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1128398003885	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
1128398003886	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398003887	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1128398003888	putative substrate translocation pore; other site
1128398003889	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1128398003890	MarR family; Region: MarR_2; pfam12802
1128398003891	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
1128398003892	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
1128398003893	nudix motif; other site
1128398003894	GTP-binding protein YchF; Reviewed; Region: PRK09601
1128398003895	YchF GTPase; Region: YchF; cd01900
1128398003896	G1 box; other site
1128398003897	GTP/Mg2+ binding site [chemical binding]; other site
1128398003898	Switch I region; other site
1128398003899	G2 box; other site
1128398003900	Switch II region; other site
1128398003901	G3 box; other site
1128398003902	G4 box; other site
1128398003903	G5 box; other site
1128398003904	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
1128398003905	PBP superfamily domain; Region: PBP_like_2; cl17296
1128398003906	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1128398003907	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
1128398003908	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003909	dimer interface [polypeptide binding]; other site
1128398003910	conserved gate region; other site
1128398003911	putative PBP binding loops; other site
1128398003912	ABC-ATPase subunit interface; other site
1128398003913	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
1128398003914	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398003915	dimer interface [polypeptide binding]; other site
1128398003916	conserved gate region; other site
1128398003917	ABC-ATPase subunit interface; other site
1128398003918	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1128398003919	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1128398003920	Walker A/P-loop; other site
1128398003921	ATP binding site [chemical binding]; other site
1128398003922	Q-loop/lid; other site
1128398003923	ABC transporter signature motif; other site
1128398003924	Walker B; other site
1128398003925	D-loop; other site
1128398003926	H-loop/switch region; other site
1128398003927	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
1128398003928	PhoU domain; Region: PhoU; pfam01895
1128398003929	PhoU domain; Region: PhoU; pfam01895
1128398003930	sporulation lipoprotein, YhcN/YlaJ family; Region: spore_YhcN_YlaJ; TIGR02898
1128398003931	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1128398003932	Class II Chelatase: a family of ATP-independent monomeric or homodimeric enzymes that catalyze the insertion of metal into protoporphyrin rings. This family includes protoporphyrin IX ferrochelatase (HemH), sirohydrochlorin ferrochelatase (SirB) and the...; Region: Chelatase_Class_II; cl02784
1128398003933	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
1128398003934	MraW methylase family; Region: Methyltransf_5; pfam01795
1128398003935	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
1128398003936	Cell division protein FtsL; Region: FtsL; cl11433
1128398003937	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
1128398003938	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1128398003939	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1128398003940	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1128398003941	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
1128398003942	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1128398003943	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398003944	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398003945	phospho-N-acetylmuramoyl-pentapeptide-transferase; Region: mraY; TIGR00445
1128398003946	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
1128398003947	Mg++ binding site [ion binding]; other site
1128398003948	putative catalytic motif [active]
1128398003949	putative substrate binding site [chemical binding]; other site
1128398003950	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
1128398003951	Formate/glycerate dehydrogenases, D-specific 2-hydroxy acid dehydrogenases and related dehydrogenases; Region: FDH_GDH_like; cl17240
1128398003952	NAD binding site [chemical binding]; other site
1128398003953	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398003954	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398003955	cell division protein FtsW; Region: ftsW; TIGR02614
1128398003956	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
1128398003957	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
1128398003958	active site
1128398003959	homodimer interface [polypeptide binding]; other site
1128398003960	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1128398003961	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1128398003962	hinge; other site
1128398003963	active site
1128398003964	Cell division septal protein [Cell envelope biogenesis, outer membrane]; Region: FtsQ; COG1589
1128398003965	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
1128398003966	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1128398003967	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
1128398003968	Protein of unknown function (DUF1290); Region: DUF1290; pfam06947
1128398003969	cell division protein FtsZ; Validated; Region: PRK09330
1128398003970	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
1128398003971	nucleotide binding site [chemical binding]; other site
1128398003972	SulA interaction site; other site
1128398003973	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
1128398003974	sigma-E processing peptidase SpoIIGA; Region: spore_II_GA; TIGR02854
1128398003975	sporulation sigma factor SigE; Reviewed; Region: PRK08301
1128398003976	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398003977	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398003978	DNA binding residues [nucleotide binding]
1128398003979	sporulation sigma factor SigG; Reviewed; Region: PRK08215
1128398003980	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398003981	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1128398003982	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398003983	DNA binding residues [nucleotide binding]
1128398003984	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
1128398003985	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
1128398003986	ATP cone domain; Region: ATP-cone; pfam03477
1128398003987	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
1128398003988	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
1128398003989	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398003990	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398003991	active site
1128398003992	phosphorylation site [posttranslational modification]
1128398003993	intermolecular recognition site; other site
1128398003994	dimerization interface [polypeptide binding]; other site
1128398003995	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398003996	DNA binding site [nucleotide binding]
1128398003997	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain; Region: HAMP; smart00304
1128398003998	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1128398003999	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398004000	putative active site [active]
1128398004001	heme pocket [chemical binding]; other site
1128398004002	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398004003	dimer interface [polypeptide binding]; other site
1128398004004	phosphorylation site [posttranslational modification]
1128398004005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398004006	ATP binding site [chemical binding]; other site
1128398004007	Mg2+ binding site [ion binding]; other site
1128398004008	G-X-G motif; other site
1128398004009	Tic20-like protein; Region: Tic20; pfam09685
1128398004010	recombination factor protein RarA; Reviewed; Region: PRK13342
1128398004011	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398004012	Walker A motif; other site
1128398004013	ATP binding site [chemical binding]; other site
1128398004014	Walker B motif; other site
1128398004015	arginine finger; other site
1128398004016	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
1128398004017	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
1128398004018	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
1128398004019	putative dimer interface [polypeptide binding]; other site
1128398004020	putative anticodon binding site; other site
1128398004021	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
1128398004022	homodimer interface [polypeptide binding]; other site
1128398004023	motif 1; other site
1128398004024	motif 2; other site
1128398004025	active site
1128398004026	motif 3; other site
1128398004027	hypothetical protein; Provisional; Region: PRK05590
1128398004028	Protein of unknown function (DUF2837); Region: DUF2837; pfam10997
1128398004029	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1128398004030	active site
1128398004031	Glyco_18 domain; Region: Glyco_18; smart00636
1128398004032	S-layer homology domain; Region: SLH; pfam00395
1128398004033	S-layer homology domain; Region: SLH; pfam00395
1128398004034	S-layer homology domain; Region: SLH; pfam00395
1128398004035	Peptidase M14 carboxypeptidase family-like domain of Endopeptidase I; Region: M14_Endopeptidase_I; cd06229
1128398004036	putative active site [active]
1128398004037	Zn binding site [ion binding]; other site
1128398004038	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1128398004039	Transcriptional regulator; Region: Rrf2; cl17282
1128398004040	Rrf2 family protein; Region: rrf2_super; TIGR00738
1128398004041	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
1128398004042	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
1128398004043	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398004044	catalytic residue [active]
1128398004045	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
1128398004046	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
1128398004047	trimerization site [polypeptide binding]; other site
1128398004048	active site
1128398004049	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
1128398004050	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
1128398004051	Ligand Binding Site [chemical binding]; other site
1128398004052	PRC-barrel domain containing protein [General function prediction only]; Region: COG3881
1128398004053	PRC-barrel domain; Region: PRC; pfam05239
1128398004054	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
1128398004055	Domain of unknown function DUF20; Region: UPF0118; pfam01594
1128398004056	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
1128398004057	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
1128398004058	motif 1; other site
1128398004059	active site
1128398004060	motif 2; other site
1128398004061	motif 3; other site
1128398004062	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
1128398004063	Bacterial protein of unknown function (DUF965); Region: DUF965; cl01857
1128398004064	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
1128398004065	Aldo/keto reductase family; Region: Aldo_ket_red; pfam00248
1128398004066	active site
1128398004067	catalytic tetrad [active]
1128398004068	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398004069	Uncharacterized protein family (UPF0081); Region: UPF0081; pfam03652
1128398004070	ferric uptake regulator; Provisional; Region: fur; PRK09462
1128398004071	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1128398004072	metal binding site 2 [ion binding]; metal-binding site
1128398004073	putative DNA binding helix; other site
1128398004074	metal binding site 1 [ion binding]; metal-binding site
1128398004075	dimer interface [polypeptide binding]; other site
1128398004076	structural Zn2+ binding site [ion binding]; other site
1128398004077	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
1128398004078	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398004079	RNA-metabolising metallo-beta-lactamase; Region: RMMBL; pfam07521
1128398004080	QueT transporter; Region: QueT; pfam06177
1128398004081	Predicted O-methyltransferase [General function prediction only]; Region: COG4122
1128398004082	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004083	S-adenosylmethionine binding site [chemical binding]; other site
1128398004084	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
1128398004085	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl07974
1128398004086	active site
1128398004087	Peptidase family U32; Region: Peptidase_U32; pfam01136
1128398004088	metal binding site [ion binding]; metal-binding site
1128398004089	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
1128398004090	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
1128398004091	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
1128398004092	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398004093	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1128398004094	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1128398004095	catalytic residues [active]
1128398004096	catalytic nucleophile [active]
1128398004097	Presynaptic Site I dimer interface [polypeptide binding]; other site
1128398004098	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1128398004099	Synaptic Flat tetramer interface [polypeptide binding]; other site
1128398004100	Synaptic Site I dimer interface [polypeptide binding]; other site
1128398004101	DNA binding site [nucleotide binding]
1128398004102	Recombinase; Region: Recombinase; pfam07508
1128398004103	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1128398004104	Coat F domain; Region: Coat_F; pfam07875
1128398004105	Helix-turn-helix domain; Region: HTH_36; pfam13730
1128398004106	Domain of Unknown Function (DUF1259); Region: DUF1529; pfam07485
1128398004107	Cupin domain; Region: Cupin_2; cl17218
1128398004108	YmaF family; Region: YmaF; pfam12788
1128398004109	sporulation sigma factor SigK; Reviewed; Region: PRK05803
1128398004110	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398004111	DNA binding residues [nucleotide binding]
1128398004112	Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ); Region: Spore_YhcN_YlaJ; pfam09580
1128398004113	Superoxide dismutase [Fe]; Provisional; Region: PTZ00078
1128398004114	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
1128398004115	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
1128398004116	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
1128398004117	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
1128398004118	shikimate binding site; other site
1128398004119	NAD(P) binding site [chemical binding]; other site
1128398004120	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; cl06830
1128398004121	type IV pilus modification protein PilV; Region: type_IV_pilV; TIGR02523
1128398004122	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
1128398004123	elongation factor P; Validated; Region: PRK00529
1128398004124	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
1128398004125	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
1128398004126	RNA binding site [nucleotide binding]; other site
1128398004127	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
1128398004128	RNA binding site [nucleotide binding]; other site
1128398004129	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
1128398004130	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
1128398004131	Walker A motif; other site
1128398004132	ATP binding site [chemical binding]; other site
1128398004133	stage III sporulation protein SpoAB; Provisional; Region: PRK08307
1128398004134	stage III sporulation protein AC; Region: spore_III_AC; TIGR02848
1128398004135	stage III sporulation protein AD; Region: spore_III_AD; TIGR02849
1128398004136	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; pfam09546
1128398004137	stage III sporulation protein AF; Region: spore_III_AF; TIGR02896
1128398004138	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
1128398004139	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
1128398004140	Asp23 family; Region: Asp23; pfam03780
1128398004141	Asp23 family; Region: Asp23; pfam03780
1128398004142	Small integral membrane protein (DUF2273); Region: DUF2273; pfam10031
1128398004143	transcription antitermination protein NusB; Reviewed; Region: nusB; PRK00202
1128398004144	putative RNA binding site [nucleotide binding]; other site
1128398004145	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
1128398004146	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
1128398004147	generic binding surface II; other site
1128398004148	generic binding surface I; other site
1128398004149	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
1128398004150	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
1128398004151	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
1128398004152	substrate binding pocket [chemical binding]; other site
1128398004153	chain length determination region; other site
1128398004154	substrate-Mg2+ binding site; other site
1128398004155	catalytic residues [active]
1128398004156	aspartate-rich region 1; other site
1128398004157	active site lid residues [active]
1128398004158	aspartate-rich region 2; other site
1128398004159	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
1128398004160	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
1128398004161	TPP-binding site; other site
1128398004162	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1128398004163	PYR/PP interface [polypeptide binding]; other site
1128398004164	dimer interface [polypeptide binding]; other site
1128398004165	TPP binding site [chemical binding]; other site
1128398004166	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1128398004167	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
1128398004168	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398004169	RNA binding surface [nucleotide binding]; other site
1128398004170	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
1128398004171	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
1128398004172	arginine repressor; Provisional; Region: argR; PRK00441
1128398004173	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
1128398004174	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
1128398004175	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1128398004176	Walker A/P-loop; other site
1128398004177	ATP binding site [chemical binding]; other site
1128398004178	Q-loop/lid; other site
1128398004179	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
1128398004180	ABC transporter signature motif; other site
1128398004181	Walker B; other site
1128398004182	D-loop; other site
1128398004183	H-loop/switch region; other site
1128398004184	stage IV sporulation protein B; Region: spore_IV_B; TIGR02860
1128398004185	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1128398004186	protein binding site [polypeptide binding]; other site
1128398004187	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
1128398004188	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
1128398004189	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398004190	active site
1128398004191	phosphorylation site [posttranslational modification]
1128398004192	intermolecular recognition site; other site
1128398004193	dimerization interface [polypeptide binding]; other site
1128398004194	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
1128398004195	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398004196	active site
1128398004197	Int/Topo IB signature motif; other site
1128398004198	DNA binding site [nucleotide binding]
1128398004199	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
1128398004200	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4825
1128398004201	Thiamine pyrophosphokinase; Region: TPK; cl08415
1128398004202	Protein of unknown function (DUF3186); Region: DUF3186; pfam11382
1128398004203	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1128398004204	Ligand binding site; other site
1128398004205	Putative Catalytic site; other site
1128398004206	DXD motif; other site
1128398004207	Glycosyltransferase 4 (GT4) includes both eukaryotic and prokaryotic UDP-D-N-acetylhexosamine:polyprenol phosphate D-N-acetylhexosamine-1-phosphate transferases. They catalyze the transfer of a D-N-acetylhexosamine 1-phosphate to a membrane-bound...; Region: GT_MraY-like; cl10571
1128398004208	putative catalytic motif [active]
1128398004209	Protein of unknown function (DUF3866); Region: DUF3866; pfam12982
1128398004210	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
1128398004211	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
1128398004212	dimer interface [polypeptide binding]; other site
1128398004213	ADP-ribose binding site [chemical binding]; other site
1128398004214	active site
1128398004215	nudix motif; other site
1128398004216	metal binding site [ion binding]; metal-binding site
1128398004217	Integral membrane protein DUF95; Region: DUF95; cl00572
1128398004218	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
1128398004219	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
1128398004220	active site
1128398004221	Int/Topo IB signature motif; other site
1128398004222	purine nucleoside phosphorylase; Provisional; Region: PRK08202
1128398004223	pyrimidine-nucleoside phosphorylase; Region: Y_phosphoryl; TIGR02644
1128398004224	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
1128398004225	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
1128398004226	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
1128398004227	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398004228	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1128398004229	Alpha/beta hydrolase of unknown function (DUF1057); Region: DUF1057; pfam06342
1128398004230	Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only]; Region: MhpC; COG0596
1128398004231	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
1128398004232	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
1128398004233	Peptidase family M50; Region: Peptidase_M50; pfam02163
1128398004234	active site
1128398004235	putative substrate binding region [chemical binding]; other site
1128398004236	segregation and condensation protein A; Reviewed; Region: scpA; PRK00104
1128398004237	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
1128398004238	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
1128398004239	sporulation protein YtfJ; Region: spore_ytfJ; TIGR02874
1128398004240	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398004241	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1128398004242	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; pfam07943
1128398004243	hypothetical protein; Provisional; Region: PRK05802
1128398004244	FAD/NAD binding domain (electron transfer subunit) of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate...; Region: DHOD_e_trans_like; cd06192
1128398004245	FAD binding pocket [chemical binding]; other site
1128398004246	FAD binding motif [chemical binding]; other site
1128398004247	phosphate binding motif [ion binding]; other site
1128398004248	beta-alpha-beta structure motif; other site
1128398004249	NAD binding pocket [chemical binding]; other site
1128398004250	Iron coordination center [ion binding]; other site
1128398004251	Glucose inhibited division protein A; Region: GIDA; pfam01134
1128398004252	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1128398004253	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1128398004254	catalytic residues [active]
1128398004255	catalytic nucleophile [active]
1128398004256	Presynaptic Site I dimer interface [polypeptide binding]; other site
1128398004257	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1128398004258	Synaptic Flat tetramer interface [polypeptide binding]; other site
1128398004259	Synaptic Site I dimer interface [polypeptide binding]; other site
1128398004260	DNA binding site [nucleotide binding]
1128398004261	Recombinase; Region: Recombinase; pfam07508
1128398004262	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1128398004263	Accessory gene regulator B; Region: AgrB; cl01873
1128398004264	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
1128398004265	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004266	S-adenosylmethionine binding site [chemical binding]; other site
1128398004267	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1128398004268	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
1128398004269	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398004270	RNA binding surface [nucleotide binding]; other site
1128398004271	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
1128398004272	active site
1128398004273	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004274	Coenzyme A binding pocket [chemical binding]; other site
1128398004275	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398004276	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004277	S-adenosylmethionine binding site [chemical binding]; other site
1128398004278	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
1128398004279	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
1128398004280	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
1128398004281	putative active site [active]
1128398004282	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
1128398004283	catalytic core [active]
1128398004284	flavoprotein, HI0933 family; Region: TIGR00275
1128398004285	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1128398004286	cytidylate kinase; Provisional; Region: cmk; PRK00023
1128398004287	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
1128398004288	CMP-binding site; other site
1128398004289	The sites determining sugar specificity; other site
1128398004290	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1128398004291	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1128398004292	putative acyl-acceptor binding pocket; other site
1128398004293	4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein; Reviewed; Region: PRK00087
1128398004294	LytB protein; Region: LYTB; cl00507
1128398004295	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1128398004296	RNA binding site [nucleotide binding]; other site
1128398004297	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
1128398004298	RNA binding site [nucleotide binding]; other site
1128398004299	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
1128398004300	RNA binding site [nucleotide binding]; other site
1128398004301	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1128398004302	RNA binding site [nucleotide binding]; other site
1128398004303	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
1128398004304	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
1128398004305	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
1128398004306	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1128398004307	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1128398004308	oligomer interface [polypeptide binding]; other site
1128398004309	active site
1128398004310	metal binding site [ion binding]; metal-binding site
1128398004311	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1128398004312	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1128398004313	oligomer interface [polypeptide binding]; other site
1128398004314	active site
1128398004315	metal binding site [ion binding]; metal-binding site
1128398004316	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
1128398004317	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
1128398004318	oligomer interface [polypeptide binding]; other site
1128398004319	active site
1128398004320	metal binding site [ion binding]; metal-binding site
1128398004321	MerR HTH family regulatory protein; Region: MerR_1; pfam13411
1128398004322	Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators; Region: HTH_MlrA-like_sg1; cd04764
1128398004323	DNA binding residues [nucleotide binding]
1128398004324	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398004325	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1128398004326	DNA-binding site [nucleotide binding]; DNA binding site
1128398004327	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398004328	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398004329	homodimer interface [polypeptide binding]; other site
1128398004330	catalytic residue [active]
1128398004331	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398004332	non-specific DNA binding site [nucleotide binding]; other site
1128398004333	salt bridge; other site
1128398004334	sequence-specific DNA binding site [nucleotide binding]; other site
1128398004335	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1128398004336	active site
1128398004337	catalytic residues [active]
1128398004338	metal binding site [ion binding]; metal-binding site
1128398004339	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004340	Coenzyme A binding pocket [chemical binding]; other site
1128398004341	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1128398004342	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004343	Coenzyme A binding pocket [chemical binding]; other site
1128398004344	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
1128398004345	aspartate racemase; Region: asp_race; TIGR00035
1128398004346	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1128398004347	Acetokinase family; Region: Acetate_kinase; cl17229
1128398004348	MUG-like Uracil-DNA glycosylase enzyme family; Region: UDG_MUG_like; cd10032
1128398004349	putative active site [active]
1128398004350	CAAX protease self-immunity; Region: Abi; pfam02517
1128398004351	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398004352	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398004353	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
1128398004354	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398004355	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004356	Coenzyme A binding pocket [chemical binding]; other site
1128398004357	Protein of unknown function (DUF3888); Region: DUF3888; pfam13027
1128398004358	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1128398004359	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004360	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1128398004361	Coenzyme A binding pocket [chemical binding]; other site
1128398004362	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1128398004363	pullulanase, extracellular, Gram-positive; Region: pullulan_Gpos; TIGR02102
1128398004364	Ferritin-like domain; Region: Ferritin; pfam00210
1128398004365	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1128398004366	dinuclear metal binding motif [ion binding]; other site
1128398004367	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
1128398004368	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
1128398004369	SpoVT / AbrB like domain; Region: SpoVT_AbrB; smart00966
1128398004370	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
1128398004371	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398004372	Coenzyme A binding pocket [chemical binding]; other site
1128398004373	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1128398004374	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; cl00877
1128398004375	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
1128398004376	HTH-like domain; Region: HTH_21; pfam13276
1128398004377	Integrase core domain; Region: rve; pfam00665
1128398004378	Integrase core domain; Region: rve_3; pfam13683
1128398004379	YmaF family; Region: YmaF; pfam12788
1128398004380	Protein of unknown function (DUF968); Region: DUF968; pfam06147
1128398004381	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1128398004382	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398004383	Phage terminase small subunit; Region: Phage_terminase; pfam10668
1128398004384	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
1128398004385	Baseplate J-like protein; Region: Baseplate_J; pfam04865
1128398004386	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
1128398004387	Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates as well as playing roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold...; Region: Sialidase; cl17698
1128398004388	Asp-box motif; other site
1128398004389	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398004390	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398004391	active site
1128398004392	metal binding site [ion binding]; metal-binding site
1128398004393	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398004394	NADPH:quinone reductase and related Zn-dependent oxidoreductases [Energy production and conversion / General function prediction only]; Region: Qor; COG0604
1128398004395	alcohol dehydrogenase and quinone reductase-like medium chain degydrogenases/reductases; Region: MDR_like_2; cd05289
1128398004396	putative NAD(P) binding site [chemical binding]; other site
1128398004397	Predicted transcriptional regulators [Transcription]; Region: COG1733
1128398004398	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398004399	putative DNA binding site [nucleotide binding]; other site
1128398004400	dimerization interface [polypeptide binding]; other site
1128398004401	putative Zn2+ binding site [ion binding]; other site
1128398004402	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328
1128398004403	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1128398004404	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398004405	FeS/SAM binding site; other site
1128398004406	TRAM domain; Region: TRAM; pfam01938
1128398004407	Protein of unknown function (DUF964); Region: DUF964; pfam06133
1128398004408	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
1128398004409	MutS domain I; Region: MutS_I; pfam01624
1128398004410	MutS domain II; Region: MutS_II; pfam05188
1128398004411	MutS domain III; Region: MutS_III; pfam05192
1128398004412	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
1128398004413	Walker A/P-loop; other site
1128398004414	ATP binding site [chemical binding]; other site
1128398004415	Q-loop/lid; other site
1128398004416	ABC transporter signature motif; other site
1128398004417	Walker B; other site
1128398004418	D-loop; other site
1128398004419	H-loop/switch region; other site
1128398004420	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
1128398004421	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398004422	ATP binding site [chemical binding]; other site
1128398004423	Mg2+ binding site [ion binding]; other site
1128398004424	G-X-G motif; other site
1128398004425	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
1128398004426	ATP binding site [chemical binding]; other site
1128398004427	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
1128398004428	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
1128398004429	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
1128398004430	bacterial Hfq-like; Region: Hfq; cd01716
1128398004431	hexamer interface [polypeptide binding]; other site
1128398004432	Sm1 motif; other site
1128398004433	RNA binding site [nucleotide binding]; other site
1128398004434	Sm2 motif; other site
1128398004435	stage V sporulation protein K; Region: spore_V_K; TIGR02881
1128398004436	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398004437	Walker A motif; other site
1128398004438	ATP binding site [chemical binding]; other site
1128398004439	Walker B motif; other site
1128398004440	arginine finger; other site
1128398004441	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
1128398004442	G1 box; other site
1128398004443	GTP/Mg2+ binding site [chemical binding]; other site
1128398004444	G2 box; other site
1128398004445	Switch I region; other site
1128398004446	G3 box; other site
1128398004447	Switch II region; other site
1128398004448	G4 box; other site
1128398004449	G5 box; other site
1128398004450	Aluminium resistance protein; Region: Alum_res; pfam06838
1128398004451	Cystathionine beta-lyase family protein involved in aluminum resistance [Inorganic ion transport and metabolism]; Region: COG4100
1128398004452	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
1128398004453	LexA repressor; Validated; Region: PRK00215
1128398004454	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
1128398004455	Catalytic site [active]
1128398004456	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
1128398004457	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
1128398004458	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
1128398004459	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
1128398004460	active site
1128398004461	substrate binding site [chemical binding]; other site
1128398004462	trimer interface [polypeptide binding]; other site
1128398004463	CoA binding site [chemical binding]; other site
1128398004464	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
1128398004465	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398004466	active site
1128398004467	DNA binding site [nucleotide binding]
1128398004468	Int/Topo IB signature motif; other site
1128398004469	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
1128398004470	NlpC/P60 family; Region: NLPC_P60; pfam00877
1128398004471	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004472	S-adenosylmethionine binding site [chemical binding]; other site
1128398004473	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
1128398004474	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Region: MTA/SAH-Nsdase; TIGR01704
1128398004475	S-ribosylhomocysteinase; Provisional; Region: PRK02260
1128398004476	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
1128398004477	Glycosyl hydrolase family 3 N terminal domain; Region: Glyco_hydro_3; pfam00933
1128398004478	helicase 45; Provisional; Region: PTZ00424
1128398004479	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
1128398004480	ATP binding site [chemical binding]; other site
1128398004481	putative Mg++ binding site [ion binding]; other site
1128398004482	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398004483	nucleotide binding region [chemical binding]; other site
1128398004484	ATP-binding site [chemical binding]; other site
1128398004485	aspartate aminotransferase; Provisional; Region: PRK05764
1128398004486	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398004487	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398004488	homodimer interface [polypeptide binding]; other site
1128398004489	catalytic residue [active]
1128398004490	Predicted transcriptional regulators [Transcription]; Region: COG1695
1128398004491	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1128398004492	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
1128398004493	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1128398004494	active site
1128398004495	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
1128398004496	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
1128398004497	Domain of unknown function (DUF3552); Region: DUF3552; pfam12072
1128398004498	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
1128398004499	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398004500	Zn2+ binding site [ion binding]; other site
1128398004501	Mg2+ binding site [ion binding]; other site
1128398004502	recombinase A; Provisional; Region: recA; PRK09354
1128398004503	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
1128398004504	hexamer interface [polypeptide binding]; other site
1128398004505	Walker A motif; other site
1128398004506	ATP binding site [chemical binding]; other site
1128398004507	Walker B motif; other site
1128398004508	Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA [General function prediction only]; Region: CinA; COG1058
1128398004509	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
1128398004510	putative MPT binding site; other site
1128398004511	Competence-damaged protein; Region: CinA; pfam02464
1128398004512	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Region: pgsA; TIGR00560
1128398004513	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
1128398004514	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1128398004515	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398004516	FeS/SAM binding site; other site
1128398004517	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
1128398004518	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
1128398004519	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
1128398004520	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1128398004521	active site
1128398004522	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
1128398004523	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
1128398004524	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
1128398004525	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
1128398004526	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
1128398004527	Putative catalytic NodB homology domain of uncharacterized protein YlxY from Bacillus subtilis and its bacterial homologs; Region: CE4_BsYlxY_like; cd10950
1128398004528	NodB motif; other site
1128398004529	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
1128398004530	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
1128398004531	RNase E interface [polypeptide binding]; other site
1128398004532	trimer interface [polypeptide binding]; other site
1128398004533	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
1128398004534	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
1128398004535	RNase E interface [polypeptide binding]; other site
1128398004536	trimer interface [polypeptide binding]; other site
1128398004537	active site
1128398004538	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
1128398004539	putative nucleic acid binding region [nucleotide binding]; other site
1128398004540	G-X-X-G motif; other site
1128398004541	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
1128398004542	RNA binding site [nucleotide binding]; other site
1128398004543	domain interface; other site
1128398004544	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
1128398004545	16S/18S rRNA binding site [nucleotide binding]; other site
1128398004546	S13e-L30e interaction site [polypeptide binding]; other site
1128398004547	25S rRNA binding site [nucleotide binding]; other site
1128398004548	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
1128398004549	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
1128398004550	active site
1128398004551	Riboflavin kinase; Region: Flavokinase; pfam01687
1128398004552	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
1128398004553	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
1128398004554	RNA binding site [nucleotide binding]; other site
1128398004555	active site
1128398004556	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
1128398004557	DHH family; Region: DHH; pfam01368
1128398004558	DHHA1 domain; Region: DHHA1; pfam02272
1128398004559	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
1128398004560	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1128398004561	translation initiation factor IF-2; Region: IF-2; TIGR00487
1128398004562	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
1128398004563	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
1128398004564	G1 box; other site
1128398004565	putative GEF interaction site [polypeptide binding]; other site
1128398004566	GTP/Mg2+ binding site [chemical binding]; other site
1128398004567	Switch I region; other site
1128398004568	G2 box; other site
1128398004569	G3 box; other site
1128398004570	Switch II region; other site
1128398004571	G4 box; other site
1128398004572	G5 box; other site
1128398004573	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
1128398004574	Translation-initiation factor 2; Region: IF-2; pfam11987
1128398004575	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
1128398004576	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
1128398004577	putative RNA binding cleft [nucleotide binding]; other site
1128398004578	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
1128398004579	NusA N-terminal domain; Region: NusA_N; pfam08529
1128398004580	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
1128398004581	RNA binding site [nucleotide binding]; other site
1128398004582	homodimer interface [polypeptide binding]; other site
1128398004583	NusA-like KH domain; Region: KH_5; pfam13184
1128398004584	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
1128398004585	G-X-X-G motif; other site
1128398004586	ribosome maturation protein RimP; Reviewed; Region: PRK00092
1128398004587	Sm and related proteins; Region: Sm_like; cl00259
1128398004588	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
1128398004589	putative oligomer interface [polypeptide binding]; other site
1128398004590	putative RNA binding site [nucleotide binding]; other site
1128398004591	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1128398004592	MgtC family; Region: MgtC; pfam02308
1128398004593	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
1128398004594	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
1128398004595	Ligand binding site; other site
1128398004596	Putative Catalytic site; other site
1128398004597	DXD motif; other site
1128398004598	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1128398004599	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
1128398004600	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
1128398004601	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
1128398004602	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
1128398004603	active site
1128398004604	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1128398004605	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
1128398004606	putative substrate binding region [chemical binding]; other site
1128398004607	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
1128398004608	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
1128398004609	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
1128398004610	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
1128398004611	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
1128398004612	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
1128398004613	Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS); homodimers which catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl...; Region: CIS_IPPS; cl00230
1128398004614	Putative undecaprenyl diphosphate synthase; Region: Prenyltransf; pfam01255
1128398004615	catalytic residue [active]
1128398004616	putative FPP diphosphate  binding site; other site
1128398004617	putative FPP binding hydrophobic cleft; other site
1128398004618	dimer interface [polypeptide binding]; other site
1128398004619	putative IPP diphosphate binding site; other site
1128398004620	ribosome recycling factor; Reviewed; Region: frr; PRK00083
1128398004621	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
1128398004622	hinge region; other site
1128398004623	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
1128398004624	putative nucleotide binding site [chemical binding]; other site
1128398004625	uridine monophosphate binding site [chemical binding]; other site
1128398004626	homohexameric interface [polypeptide binding]; other site
1128398004627	elongation factor Ts; Reviewed; Region: tsf; PRK12332
1128398004628	UBA/TS-N domain; Region: UBA; pfam00627
1128398004629	Elongation factor TS; Region: EF_TS; pfam00889
1128398004630	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
1128398004631	rRNA interaction site [nucleotide binding]; other site
1128398004632	S8 interaction site; other site
1128398004633	putative laminin-1 binding site; other site
1128398004634	Protein of unknown function (DUF342); Region: DUF342; pfam03961
1128398004635	RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479
1128398004636	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398004637	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1128398004638	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398004639	DNA binding residues [nucleotide binding]
1128398004640	chemoreceptor glutamine deamidase CheD; Provisional; Region: PRK13488
1128398004641	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
1128398004642	CheC-like family; Region: CheC; pfam04509
1128398004643	Chemotaxis phosphatase CheX; Region: CheX; cl15816
1128398004644	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
1128398004645	putative CheA interaction surface; other site
1128398004646	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
1128398004647	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
1128398004648	putative binding surface; other site
1128398004649	active site
1128398004650	P2 response regulator binding domain; Region: P2; pfam07194
1128398004651	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
1128398004652	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398004653	ATP binding site [chemical binding]; other site
1128398004654	Mg2+ binding site [ion binding]; other site
1128398004655	G-X-G motif; other site
1128398004656	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
1128398004657	cell division ATPase MinD, archaeal; Region: minD_arch; TIGR01969
1128398004658	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398004659	Flagellar GTP-binding protein [Cell motility and secretion]; Region: FlhF; COG1419
1128398004660	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
1128398004661	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
1128398004662	FHIPEP family; Region: FHIPEP; pfam00771
1128398004663	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
1128398004664	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257
1128398004665	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
1128398004666	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
1128398004667	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
1128398004668	flagellar biosynthetic protein FliO; Region: FliO_TIGR; TIGR03500
1128398004669	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398004670	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398004671	active site
1128398004672	phosphorylation site [posttranslational modification]
1128398004673	intermolecular recognition site; other site
1128398004674	dimerization interface [polypeptide binding]; other site
1128398004675	flagellar motor switch protein; Validated; Region: PRK08119
1128398004676	CheC-like family; Region: CheC; pfam04509
1128398004677	CheC-like family; Region: CheC; pfam04509
1128398004678	flagellar motor switch protein FliN; Region: fliN; TIGR02480
1128398004679	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
1128398004680	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
1128398004681	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
1128398004682	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
1128398004683	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
1128398004684	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
1128398004685	ligand binding site [chemical binding]; other site
1128398004686	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
1128398004687	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
1128398004688	Flagellar protein (FlbD); Region: FlbD; pfam06289
1128398004689	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
1128398004690	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1128398004691	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
1128398004692	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398004693	Protein of unknown function (DUF3766); Region: DUF3766; cl11797
1128398004694	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
1128398004695	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
1128398004696	flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497
1128398004697	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
1128398004698	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
1128398004699	Walker A motif/ATP binding site; other site
1128398004700	Walker B motif; other site
1128398004701	Flagellar assembly protein FliH; Region: FliH; pfam02108
1128398004702	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
1128398004703	FliG C-terminal domain; Region: FliG_C; pfam01706
1128398004704	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
1128398004705	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
1128398004706	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
1128398004707	Flagellar hook-basal body complex protein FliE; Region: FliE; pfam02049
1128398004708	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
1128398004709	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
1128398004710	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
1128398004711	Flagellar basal body protein [Cell motility and secretion]; Region: FlgB; COG1815
1128398004712	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK07182
1128398004713	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
1128398004714	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398004715	Walker A motif; other site
1128398004716	ATP binding site [chemical binding]; other site
1128398004717	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1128398004718	Walker B motif; other site
1128398004719	arginine finger; other site
1128398004720	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1128398004721	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
1128398004722	active site
1128398004723	HslU subunit interaction site [polypeptide binding]; other site
1128398004724	DNA topoisomerase I; Validated; Region: PRK05582
1128398004725	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
1128398004726	active site
1128398004727	interdomain interaction site; other site
1128398004728	putative metal-binding site [ion binding]; other site
1128398004729	nucleotide binding site [chemical binding]; other site
1128398004730	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
1128398004731	domain I; other site
1128398004732	DNA binding groove [nucleotide binding]
1128398004733	phosphate binding site [ion binding]; other site
1128398004734	domain II; other site
1128398004735	domain III; other site
1128398004736	nucleotide binding site [chemical binding]; other site
1128398004737	catalytic site [active]
1128398004738	domain IV; other site
1128398004739	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1128398004740	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
1128398004741	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
1128398004742	DNA protecting protein DprA; Region: dprA; TIGR00732
1128398004743	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398004744	putative DNA binding site [nucleotide binding]; other site
1128398004745	putative Zn2+ binding site [ion binding]; other site
1128398004746	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
1128398004747	active site
1128398004748	Flagellar hook-length control protein FliK; Region: Flg_hook; cl17777
1128398004749	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
1128398004750	RNA/DNA hybrid binding site [nucleotide binding]; other site
1128398004751	active site
1128398004752	GTPase YlqF; Reviewed; Region: rbgA; PRK09563
1128398004753	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
1128398004754	GTP/Mg2+ binding site [chemical binding]; other site
1128398004755	G4 box; other site
1128398004756	G5 box; other site
1128398004757	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
1128398004758	G1 box; other site
1128398004759	G1 box; other site
1128398004760	GTP/Mg2+ binding site [chemical binding]; other site
1128398004761	Switch I region; other site
1128398004762	G2 box; other site
1128398004763	G2 box; other site
1128398004764	G3 box; other site
1128398004765	G3 box; other site
1128398004766	Switch II region; other site
1128398004767	Switch II region; other site
1128398004768	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
1128398004769	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
1128398004770	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
1128398004771	RimM N-terminal domain; Region: RimM; pfam01782
1128398004772	PRC-barrel domain; Region: PRC; pfam05239
1128398004773	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
1128398004774	hypothetical protein; Provisional; Region: PRK00468
1128398004775	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
1128398004776	signal recognition particle protein; Provisional; Region: PRK10867
1128398004777	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
1128398004778	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1128398004779	P loop; other site
1128398004780	GTP binding site [chemical binding]; other site
1128398004781	Signal peptide binding domain; Region: SRP_SPB; pfam02978
1128398004782	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398004783	DNA binding residues [nucleotide binding]
1128398004784	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
1128398004785	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
1128398004786	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
1128398004787	P loop; other site
1128398004788	GTP binding site [chemical binding]; other site
1128398004789	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
1128398004790	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1128398004791	Walker A/P-loop; other site
1128398004792	ATP binding site [chemical binding]; other site
1128398004793	Q-loop/lid; other site
1128398004794	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
1128398004795	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
1128398004796	Q-loop/lid; other site
1128398004797	ABC transporter signature motif; other site
1128398004798	Walker B; other site
1128398004799	D-loop; other site
1128398004800	H-loop/switch region; other site
1128398004801	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
1128398004802	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398004803	FeS/SAM binding site; other site
1128398004804	ribonuclease III; Reviewed; Region: rnc; PRK00102
1128398004805	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
1128398004806	dimerization interface [polypeptide binding]; other site
1128398004807	active site
1128398004808	metal binding site [ion binding]; metal-binding site
1128398004809	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
1128398004810	dsRNA binding site [nucleotide binding]; other site
1128398004811	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
1128398004812	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
1128398004813	dimer interface [polypeptide binding]; other site
1128398004814	active site
1128398004815	acyl carrier protein; Provisional; Region: acpP; PRK00982
1128398004816	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
1128398004817	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
1128398004818	NAD(P) binding site [chemical binding]; other site
1128398004819	homotetramer interface [polypeptide binding]; other site
1128398004820	homodimer interface [polypeptide binding]; other site
1128398004821	active site
1128398004822	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
1128398004823	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
1128398004824	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
1128398004825	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
1128398004826	FMN binding site [chemical binding]; other site
1128398004827	substrate binding site [chemical binding]; other site
1128398004828	putative catalytic residue [active]
1128398004829	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
1128398004830	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
1128398004831	dimer interface [polypeptide binding]; other site
1128398004832	active site
1128398004833	CoA binding pocket [chemical binding]; other site
1128398004834	putative phosphate acyltransferase; Provisional; Region: PRK05331
1128398004835	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
1128398004836	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cd03440
1128398004837	active site 2 [active]
1128398004838	active site 1 [active]
1128398004839	Uncharacterized ACR, COG1399; Region: DUF177; cl00616
1128398004840	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
1128398004841	propionate/acetate kinase; Provisional; Region: PRK12379
1128398004842	Bacterial EndoU nuclease; Region: EndoU_bacteria; pfam14436
1128398004843	Protein of unknown function, DUF600; Region: DUF600; cl04640
1128398004844	DNA/RNA non-specific endonuclease; Region: Endonuclea_NS_2; pfam13930
1128398004845	hypothetical protein; Provisional; Region: PRK13670
1128398004846	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
1128398004847	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
1128398004848	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
1128398004849	active site
1128398004850	nucleophile elbow; other site
1128398004851	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
1128398004852	Nucleoside recognition; Region: Gate; pfam07670
1128398004853	Protein of unknown function (DUF812); Region: DUF812; pfam05667
1128398004854	phosphopantetheine adenylyltransferase; Provisional; Region: coaD; PRK00168
1128398004855	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
1128398004856	active site
1128398004857	(T/H)XGH motif; other site
1128398004858	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
1128398004859	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004860	S-adenosylmethionine binding site [chemical binding]; other site
1128398004861	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1128398004862	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398004863	catalytic loop [active]
1128398004864	iron binding site [ion binding]; other site
1128398004865	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1128398004866	4Fe-4S binding domain; Region: Fer4; pfam00037
1128398004867	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1128398004868	[4Fe-4S] binding site [ion binding]; other site
1128398004869	molybdopterin cofactor binding site; other site
1128398004870	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1128398004871	molybdopterin cofactor binding site; other site
1128398004872	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
1128398004873	Walker A motif; other site
1128398004874	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1128398004875	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1128398004876	dimer interface [polypeptide binding]; other site
1128398004877	putative functional site; other site
1128398004878	putative MPT binding site; other site
1128398004879	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1128398004880	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398004881	catalytic loop [active]
1128398004882	iron binding site [ion binding]; other site
1128398004883	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1128398004884	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398004885	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1128398004886	[4Fe-4S] binding site [ion binding]; other site
1128398004887	molybdopterin cofactor binding site; other site
1128398004888	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1128398004889	molybdopterin cofactor binding site; other site
1128398004890	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1128398004891	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
1128398004892	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
1128398004893	ssDNA binding site; other site
1128398004894	generic binding surface II; other site
1128398004895	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1128398004896	ATP binding site [chemical binding]; other site
1128398004897	putative Mg++ binding site [ion binding]; other site
1128398004898	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398004899	nucleotide binding region [chemical binding]; other site
1128398004900	ATP-binding site [chemical binding]; other site
1128398004901	Uncharacterized conserved protein [Function unknown]; Region: COG1633
1128398004902	Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB; cd01045
1128398004903	diiron binding motif [ion binding]; other site
1128398004904	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
1128398004905	DAK2 domain; Region: Dak2; pfam02734
1128398004906	Asp23 family; Region: Asp23; pfam03780
1128398004907	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
1128398004908	Thiamine pyrophosphokinase; Region: TPK; cd07995
1128398004909	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
1128398004910	active site
1128398004911	dimerization interface [polypeptide binding]; other site
1128398004912	thiamine binding site [chemical binding]; other site
1128398004913	Thiamine transporter protein (Thia_YuaJ); Region: Thia_YuaJ; pfam09515
1128398004914	Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Region: Rpe; COG0036
1128398004915	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
1128398004916	substrate binding site [chemical binding]; other site
1128398004917	hexamer interface [polypeptide binding]; other site
1128398004918	metal binding site [ion binding]; metal-binding site
1128398004919	GTPase RsgA; Reviewed; Region: PRK00098
1128398004920	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
1128398004921	RNA binding site [nucleotide binding]; other site
1128398004922	homodimer interface [polypeptide binding]; other site
1128398004923	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
1128398004924	GTPase/Zn-binding domain interface [polypeptide binding]; other site
1128398004925	GTP/Mg2+ binding site [chemical binding]; other site
1128398004926	G4 box; other site
1128398004927	G5 box; other site
1128398004928	G1 box; other site
1128398004929	Switch I region; other site
1128398004930	G2 box; other site
1128398004931	G3 box; other site
1128398004932	Switch II region; other site
1128398004933	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1128398004934	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
1128398004935	active site
1128398004936	ATP binding site [chemical binding]; other site
1128398004937	substrate binding site [chemical binding]; other site
1128398004938	activation loop (A-loop); other site
1128398004939	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1128398004940	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1128398004941	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
1128398004942	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
1128398004943	active site
1128398004944	ribosomal RNA large subunit methyltransferase N; Provisional; Region: PRK14454
1128398004945	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398004946	FeS/SAM binding site; other site
1128398004947	16S rRNA methyltransferase B; Provisional; Region: PRK14902
1128398004948	NusB family; Region: NusB; pfam01029
1128398004949	putative RNA binding site [nucleotide binding]; other site
1128398004950	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398004951	S-adenosylmethionine binding site [chemical binding]; other site
1128398004952	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
1128398004953	Protein of unknown function DUF116; Region: DUF116; pfam01976
1128398004954	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
1128398004955	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
1128398004956	putative active site [active]
1128398004957	substrate binding site [chemical binding]; other site
1128398004958	putative cosubstrate binding site; other site
1128398004959	catalytic site [active]
1128398004960	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
1128398004961	substrate binding site [chemical binding]; other site
1128398004962	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
1128398004963	active site
1128398004964	catalytic residues [active]
1128398004965	metal binding site [ion binding]; metal-binding site
1128398004966	primosomal protein N' Region: priA; TIGR00595
1128398004967	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1128398004968	ATP binding site [chemical binding]; other site
1128398004969	putative Mg++ binding site [ion binding]; other site
1128398004970	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398004971	nucleotide binding region [chemical binding]; other site
1128398004972	ATP-binding site [chemical binding]; other site
1128398004973	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
1128398004974	Flavoprotein; Region: Flavoprotein; pfam02441
1128398004975	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
1128398004976	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
1128398004977	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
1128398004978	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
1128398004979	catalytic site [active]
1128398004980	G-X2-G-X-G-K; other site
1128398004981	hypothetical protein; Provisional; Region: PRK04323
1128398004982	hypothetical protein; Provisional; Region: PRK11820
1128398004983	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
1128398004984	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
1128398004985	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
1128398004986	Domain of unknown function (DUF814); Region: DUF814; pfam05670
1128398004987	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
1128398004988	Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase [Nucleotide transport and metabolism]; Region: PyrR; COG2065
1128398004989	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398004990	active site
1128398004991	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398004992	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1128398004993	RNA binding surface [nucleotide binding]; other site
1128398004994	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1128398004995	active site
1128398004996	Signal peptidase (SPase) II; Region: Peptidase_A8; pfam01252
1128398004997	lipoprotein signal peptidase; Provisional; Region: PRK14787
1128398004998	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
1128398004999	DivIVA protein; Region: DivIVA; pfam05103
1128398005000	DivIVA domain; Region: DivI1A_domain; TIGR03544
1128398005001	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
1128398005002	RNA recognition motif (RRM) superfamily; Region: RRM_SF; cl17169
1128398005003	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398005004	RNA binding surface [nucleotide binding]; other site
1128398005005	Protein of unknown function (DUF552); Region: DUF552; cl00775
1128398005006	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
1128398005007	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1128398005008	catalytic residue [active]
1128398005009	HlyD family secretion protein; Region: HlyD_2; pfam12700
1128398005010	putative membrane fusion protein; Region: TIGR02828
1128398005011	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
1128398005012	stage IV sporulation protein A; Region: spore_IV_A; TIGR02836
1128398005013	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398005014	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398005015	S-adenosylmethionine binding site [chemical binding]; other site
1128398005016	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398005017	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398005018	Probable transposase; Region: OrfB_IS605; pfam01385
1128398005019	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398005020	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1128398005021	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1128398005022	DNA binding residues [nucleotide binding]
1128398005023	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
1128398005024	catalytic residues [active]
1128398005025	catalytic nucleophile [active]
1128398005026	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1128398005027	ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PstB; COG1117
1128398005028	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
1128398005029	Walker A/P-loop; other site
1128398005030	ATP binding site [chemical binding]; other site
1128398005031	Q-loop/lid; other site
1128398005032	ABC transporter signature motif; other site
1128398005033	Walker B; other site
1128398005034	D-loop; other site
1128398005035	H-loop/switch region; other site
1128398005036	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005037	dimer interface [polypeptide binding]; other site
1128398005038	conserved gate region; other site
1128398005039	putative PBP binding loops; other site
1128398005040	ABC-ATPase subunit interface; other site
1128398005041	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005042	dimer interface [polypeptide binding]; other site
1128398005043	conserved gate region; other site
1128398005044	putative PBP binding loops; other site
1128398005045	ABC-ATPase subunit interface; other site
1128398005046	PBP superfamily domain; Region: PBP_like_2; cl17296
1128398005047	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
1128398005048	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
1128398005049	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
1128398005050	Glycerol-3-phosphate acyltransferase; Region: G3P_acyltransf; cl00410
1128398005051	GTP-binding protein Der; Reviewed; Region: PRK00093
1128398005052	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
1128398005053	G1 box; other site
1128398005054	GTP/Mg2+ binding site [chemical binding]; other site
1128398005055	Switch I region; other site
1128398005056	G2 box; other site
1128398005057	Switch II region; other site
1128398005058	G3 box; other site
1128398005059	G4 box; other site
1128398005060	G5 box; other site
1128398005061	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
1128398005062	G1 box; other site
1128398005063	GTP/Mg2+ binding site [chemical binding]; other site
1128398005064	Switch I region; other site
1128398005065	G2 box; other site
1128398005066	G3 box; other site
1128398005067	Switch II region; other site
1128398005068	G4 box; other site
1128398005069	G5 box; other site
1128398005070	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
1128398005071	putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279
1128398005072	Protein of unknown function (DUF512); Region: DUF512; pfam04459
1128398005073	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1128398005074	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1128398005075	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398005076	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
1128398005077	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
1128398005078	putative NAD(P) binding site [chemical binding]; other site
1128398005079	active site
1128398005080	YIEGIA protein; Region: YIEGIA; pfam14045
1128398005081	serine hydroxymethyltransferase; Reviewed; Region: glyA; PRK00011
1128398005082	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
1128398005083	dimer interface [polypeptide binding]; other site
1128398005084	active site
1128398005085	glycine-pyridoxal phosphate binding site [chemical binding]; other site
1128398005086	folate binding site [chemical binding]; other site
1128398005087	Uncharacterized conserved protein [Function unknown]; Region: COG2966
1128398005088	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
1128398005089	Protein of unknown function (DUF3815); Region: DUF3815; cl01118
1128398005090	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
1128398005091	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
1128398005092	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
1128398005093	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
1128398005094	putative ATP binding site [chemical binding]; other site
1128398005095	putative substrate interface [chemical binding]; other site
1128398005096	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
1128398005097	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
1128398005098	dimer interface [polypeptide binding]; other site
1128398005099	anticodon binding site; other site
1128398005100	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1128398005101	homodimer interface [polypeptide binding]; other site
1128398005102	motif 1; other site
1128398005103	active site
1128398005104	motif 2; other site
1128398005105	GAD domain; Region: GAD; pfam02938
1128398005106	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
1128398005107	motif 3; other site
1128398005108	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
1128398005109	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1128398005110	dimer interface [polypeptide binding]; other site
1128398005111	motif 1; other site
1128398005112	active site
1128398005113	motif 2; other site
1128398005114	motif 3; other site
1128398005115	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1128398005116	anticodon binding site; other site
1128398005117	coproporphyrinogen III oxidase; Provisional; Region: PRK08207
1128398005118	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005119	FeS/SAM binding site; other site
1128398005120	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
1128398005121	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
1128398005122	putative active site [active]
1128398005123	dimerization interface [polypeptide binding]; other site
1128398005124	putative tRNAtyr binding site [nucleotide binding]; other site
1128398005125	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
1128398005126	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398005127	Zn2+ binding site [ion binding]; other site
1128398005128	Mg2+ binding site [ion binding]; other site
1128398005129	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
1128398005130	synthetase active site [active]
1128398005131	NTP binding site [chemical binding]; other site
1128398005132	metal binding site [ion binding]; metal-binding site
1128398005133	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
1128398005134	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
1128398005135	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398005136	active site
1128398005137	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
1128398005138	DHH family; Region: DHH; pfam01368
1128398005139	DHHA1 domain; Region: DHHA1; pfam02272
1128398005140	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
1128398005141	ABC1 family; Region: ABC1; pfam03109
1128398005142	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1128398005143	active site
1128398005144	ATP binding site [chemical binding]; other site
1128398005145	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
1128398005146	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
1128398005147	Protein export membrane protein; Region: SecD_SecF; pfam02355
1128398005148	protein-export membrane protein SecD; Region: secD; TIGR01129
1128398005149	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
1128398005150	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
1128398005151	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
1128398005152	trimer interface [polypeptide binding]; other site
1128398005153	putative metal binding site [ion binding]; other site
1128398005154	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
1128398005155	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005156	FeS/SAM binding site; other site
1128398005157	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
1128398005158	Protein of unknown function (DUF4001); Region: DUF4001; pfam13165
1128398005159	Protein of unknown function (DUF3792); Region: DUF3792; pfam12670
1128398005160	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1128398005161	putative active site [active]
1128398005162	putative metal binding site [ion binding]; other site
1128398005163	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1128398005164	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398005165	Coenzyme A binding pocket [chemical binding]; other site
1128398005166	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
1128398005167	metal binding site [ion binding]; metal-binding site
1128398005168	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
1128398005169	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
1128398005170	Histidine biosynthesis protein; Region: His_biosynth; pfam00977
1128398005171	substrate binding site [chemical binding]; other site
1128398005172	glutamase interaction surface [polypeptide binding]; other site
1128398005173	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
1128398005174	phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; Region: TIGR00007
1128398005175	catalytic residues [active]
1128398005176	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13141
1128398005177	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
1128398005178	putative active site [active]
1128398005179	oxyanion strand; other site
1128398005180	catalytic triad [active]
1128398005181	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
1128398005182	putative active site pocket [active]
1128398005183	4-fold oligomerization interface [polypeptide binding]; other site
1128398005184	metal binding residues [ion binding]; metal-binding site
1128398005185	3-fold/trimer interface [polypeptide binding]; other site
1128398005186	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
1128398005187	histidinol dehydrogenase; Region: hisD; TIGR00069
1128398005188	NAD binding site [chemical binding]; other site
1128398005189	dimerization interface [polypeptide binding]; other site
1128398005190	product binding site; other site
1128398005191	substrate binding site [chemical binding]; other site
1128398005192	zinc binding site [ion binding]; other site
1128398005193	catalytic residues [active]
1128398005194	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
1128398005195	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
1128398005196	ATP phosphoribosyltransferase, regulatory subunit; Region: hisZ_biosyn_reg; TIGR00443
1128398005197	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1128398005198	dimer interface [polypeptide binding]; other site
1128398005199	motif 1; other site
1128398005200	active site
1128398005201	motif 2; other site
1128398005202	motif 3; other site
1128398005203	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1128398005204	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
1128398005205	active site
1128398005206	motif I; other site
1128398005207	motif II; other site
1128398005208	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1128398005209	RecX family; Region: RecX; cl00936
1128398005210	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
1128398005211	Aminopeptidase I zinc metalloprotease (M18); Region: Peptidase_M18; pfam02127
1128398005212	active site
1128398005213	metal binding site [ion binding]; metal-binding site
1128398005214	Protein of unknown function (DUF1292); Region: DUF1292; cl01608
1128398005215	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
1128398005216	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
1128398005217	metal binding site [ion binding]; metal-binding site
1128398005218	dimer interface [polypeptide binding]; other site
1128398005219	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
1128398005220	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
1128398005221	homodimer interface [polypeptide binding]; other site
1128398005222	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398005223	catalytic residue [active]
1128398005224	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
1128398005225	H+ Antiporter protein; Region: 2A0121; TIGR00900
1128398005226	VanW like protein; Region: VanW; pfam04294
1128398005227	Predicted membrane protein [Function unknown]; Region: COG2510
1128398005228	Serine dehydratase alpha chain; Region: SDH_alpha; cl12120
1128398005229	L-serine deaminase [Amino acid transport and metabolism]; Region: SdaA; COG1760
1128398005230	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
1128398005231	Thiamine-precursor transporter protein (ThiW); Region: ThiW; pfam09512
1128398005232	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
1128398005233	dimer interface [polypeptide binding]; other site
1128398005234	substrate binding site [chemical binding]; other site
1128398005235	ATP binding site [chemical binding]; other site
1128398005236	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
1128398005237	multimerization interface [polypeptide binding]; other site
1128398005238	ATP binding site [chemical binding]; other site
1128398005239	Protein of unknown function (DUF1284); Region: DUF1284; pfam06935
1128398005240	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1128398005241	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398005242	putative DNA binding site [nucleotide binding]; other site
1128398005243	putative Zn2+ binding site [ion binding]; other site
1128398005244	PPIC-type PPIASE domain; Region: Rotamase_2; cl08278
1128398005245	pyridoxal 5'-phosphate synthase, synthase subunit Pdx1; Region: TIGR00343
1128398005246	PdxS is a subunit of the pyridoxal 5'-phosphate (PLP) synthase, an important enzyme in deoxyxylulose 5-phosphate (DXP)-independent pathway for de novo biosynthesis of PLP,  present in some eubacteria, in archaea, fungi, plants, plasmodia, and some...; Region: pdxS; cd04727
1128398005247	active site
1128398005248	multimer interface [polypeptide binding]; other site
1128398005249	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
1128398005250	anti sigma factor interaction site; other site
1128398005251	regulatory phosphorylation site [posttranslational modification]; other site
1128398005252	Cache domain; Region: Cache_1; pfam02743
1128398005253	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398005254	dimerization interface [polypeptide binding]; other site
1128398005255	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398005256	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398005257	dimer interface [polypeptide binding]; other site
1128398005258	putative CheW interface [polypeptide binding]; other site
1128398005259	Histidine kinase-like ATPase domain; Region: HATPase_c_2; pfam13581
1128398005260	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
1128398005261	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1128398005262	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1128398005263	homodimer interface [polypeptide binding]; other site
1128398005264	substrate-cofactor binding pocket; other site
1128398005265	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398005266	catalytic residue [active]
1128398005267	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
1128398005268	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1128398005269	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1128398005270	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
1128398005271	FOG: CheY-like receiver [Signal transduction mechanisms]; Region: CheY; COG0784
1128398005272	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398005273	active site
1128398005274	phosphorylation site [posttranslational modification]
1128398005275	intermolecular recognition site; other site
1128398005276	dimerization interface [polypeptide binding]; other site
1128398005277	Predicted permeases [General function prediction only]; Region: COG0679
1128398005278	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
1128398005279	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005280	FeS/SAM binding site; other site
1128398005281	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
1128398005282	ATP cone domain; Region: ATP-cone; pfam03477
1128398005283	Class III ribonucleotide reductase; Region: RNR_III; cd01675
1128398005284	effector binding site; other site
1128398005285	active site
1128398005286	Zn binding site [ion binding]; other site
1128398005287	glycine loop; other site
1128398005288	NMT1/THI5 like; Region: NMT1; pfam09084
1128398005289	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398005290	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005291	dimer interface [polypeptide binding]; other site
1128398005292	conserved gate region; other site
1128398005293	putative PBP binding loops; other site
1128398005294	ABC-ATPase subunit interface; other site
1128398005295	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398005296	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398005297	Walker A/P-loop; other site
1128398005298	ATP binding site [chemical binding]; other site
1128398005299	Q-loop/lid; other site
1128398005300	ABC transporter signature motif; other site
1128398005301	Walker B; other site
1128398005302	D-loop; other site
1128398005303	H-loop/switch region; other site
1128398005304	Putative transcription activator [Transcription]; Region: TenA; COG0819
1128398005305	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398005306	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398005307	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1128398005308	putative efflux protein, MATE family; Region: matE; TIGR00797
1128398005309	Protein of unknown function (DUF1653); Region: DUF1653; pfam07866
1128398005310	YcxB-like protein; Region: YcxB; pfam14317
1128398005311	short chain dehydrogenase; Provisional; Region: PRK06701
1128398005312	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
1128398005313	NAD binding site [chemical binding]; other site
1128398005314	metal binding site [ion binding]; metal-binding site
1128398005315	active site
1128398005316	HD domain; Region: HD_3; cl17350
1128398005317	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1128398005318	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1128398005319	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
1128398005320	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
1128398005321	Uncharacterized conserved protein [Function unknown]; Region: COG0327
1128398005322	Predicted SAM-dependent methyltransferase [General function prediction only]; Region: COG2384
1128398005323	Family of unknown function (DUF633); Region: DUF633; pfam04816
1128398005324	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
1128398005325	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
1128398005326	motif II; other site
1128398005327	HAD-hyrolase-like; Region: Hydrolase_like; pfam13242
1128398005328	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
1128398005329	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
1128398005330	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
1128398005331	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398005332	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
1128398005333	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398005334	DNA binding residues [nucleotide binding]
1128398005335	DNA primase; Validated; Region: dnaG; PRK05667
1128398005336	CHC2 zinc finger; Region: zf-CHC2; pfam01807
1128398005337	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
1128398005338	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
1128398005339	active site
1128398005340	metal binding site [ion binding]; metal-binding site
1128398005341	interdomain interaction site; other site
1128398005342	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
1128398005343	Kinase/pyrophosphorylase; Region: Kinase-PPPase; pfam03618
1128398005344	HTH domain; Region: HTH_11; pfam08279
1128398005345	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1128398005346	FOG: CBS domain [General function prediction only]; Region: COG0517
1128398005347	glycyl-tRNA synthetase; Provisional; Region: PRK04173
1128398005348	Glycyl-tRNA synthetase (GlyRS)-like class II core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes. It is responsible for the attachment of glycine to the 3...; Region: GlyRS-like_core; cd00774
1128398005349	active site
1128398005350	motif 2; other site
1128398005351	motif 3; other site
1128398005352	GlyRS Glycyl-anticodon binding domain. GlyRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: GlyRS_anticodon; cd00858
1128398005353	anticodon binding site; other site
1128398005354	Domain of unknown function (DUF4342); Region: DUF4342; pfam14242
1128398005355	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
1128398005356	Recombination protein O N terminal; Region: RecO_N; pfam11967
1128398005357	Recombination protein O C terminal; Region: RecO_C; pfam02565
1128398005358	GTPase Era; Reviewed; Region: era; PRK00089
1128398005359	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
1128398005360	G1 box; other site
1128398005361	GTP/Mg2+ binding site [chemical binding]; other site
1128398005362	Switch I region; other site
1128398005363	G2 box; other site
1128398005364	Switch II region; other site
1128398005365	G3 box; other site
1128398005366	G4 box; other site
1128398005367	G5 box; other site
1128398005368	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
1128398005369	active site
1128398005370	catalytic motif [active]
1128398005371	Zn binding site [ion binding]; other site
1128398005372	Protein of unknown function (DUF3048); Region: DUF3048; pfam11258
1128398005373	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1128398005374	Domain of unknown function DUF21; Region: DUF21; pfam01595
1128398005375	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1128398005376	Transporter associated domain; Region: CorC_HlyC; smart01091
1128398005377	Prokaryotic diacylglycerol kinase; Region: DAGK_prokar; pfam01219
1128398005378	PAP2_like proteins, diacylglycerol_kinase like sub-family. In some prokaryotes, PAP2_like phosphatase domains appear fused to E. coli DAGK-like trans-membrane diacylglycerol kinase domains. The cellular function of these architectures remains to be...; Region: PAP2_diacylglycerolkinase; cd03383
1128398005379	active site
1128398005380	metal-binding heat shock protein; Provisional; Region: PRK00016
1128398005381	Predicted membrane-associated HD superfamily hydrolase [General function prediction only]; Region: COG1480
1128398005382	7TM receptor with intracellular HD hydrolase; Region: 7TM-7TMR_HD; pfam07698
1128398005383	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398005384	Zn2+ binding site [ion binding]; other site
1128398005385	Mg2+ binding site [ion binding]; other site
1128398005386	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
1128398005387	PhoH-like protein; Region: PhoH; pfam02562
1128398005388	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
1128398005389	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
1128398005390	YabP family; Region: YabP; cl06766
1128398005391	Yqey-like protein; Region: YqeY; pfam09424
1128398005392	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
1128398005393	nucleotide binding site/active site [active]
1128398005394	HIT family signature motif; other site
1128398005395	catalytic residue [active]
1128398005396	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
1128398005397	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
1128398005398	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005399	FeS/SAM binding site; other site
1128398005400	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
1128398005401	RNA methyltransferase, RsmE family; Region: TIGR00046
1128398005402	Ribosomal protein L11 methyltransferase (PrmA); Region: PrmA; pfam06325
1128398005403	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398005404	S-adenosylmethionine binding site [chemical binding]; other site
1128398005405	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398005406	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398005407	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1128398005408	Walker A/P-loop; other site
1128398005409	ATP binding site [chemical binding]; other site
1128398005410	Q-loop/lid; other site
1128398005411	ABC transporter signature motif; other site
1128398005412	Walker B; other site
1128398005413	D-loop; other site
1128398005414	H-loop/switch region; other site
1128398005415	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398005416	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398005417	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398005418	Walker A/P-loop; other site
1128398005419	ATP binding site [chemical binding]; other site
1128398005420	Q-loop/lid; other site
1128398005421	ABC transporter signature motif; other site
1128398005422	Walker B; other site
1128398005423	D-loop; other site
1128398005424	H-loop/switch region; other site
1128398005425	chaperone protein DnaJ; Provisional; Region: PRK10767
1128398005426	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
1128398005427	HSP70 interaction site [polypeptide binding]; other site
1128398005428	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cl03262
1128398005429	substrate binding site [polypeptide binding]; other site
1128398005430	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
1128398005431	Zn binding sites [ion binding]; other site
1128398005432	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
1128398005433	dimer interface [polypeptide binding]; other site
1128398005434	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
1128398005435	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
1128398005436	nucleotide binding site [chemical binding]; other site
1128398005437	NEF interaction site [polypeptide binding]; other site
1128398005438	SBD interface [polypeptide binding]; other site
1128398005439	GrpE; Region: GrpE; pfam01025
1128398005440	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
1128398005441	dimer interface [polypeptide binding]; other site
1128398005442	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
1128398005443	coproporphyrinogen III oxidase; Provisional; Region: PRK05799
1128398005444	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005445	FeS/SAM binding site; other site
1128398005446	HemN C-terminal domain; Region: HemN_C; pfam06969
1128398005447	GTP-binding protein LepA; Provisional; Region: PRK05433
1128398005448	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
1128398005449	G1 box; other site
1128398005450	putative GEF interaction site [polypeptide binding]; other site
1128398005451	GTP/Mg2+ binding site [chemical binding]; other site
1128398005452	Switch I region; other site
1128398005453	G2 box; other site
1128398005454	G3 box; other site
1128398005455	Switch II region; other site
1128398005456	G4 box; other site
1128398005457	G5 box; other site
1128398005458	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
1128398005459	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
1128398005460	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
1128398005461	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
1128398005462	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
1128398005463	Catalytic site [active]
1128398005464	Stage II sporulation protein P (SpoIIP); Region: SpoIIP; pfam07454
1128398005465	stage II sporulation protein P; Region: spore_II_P; TIGR02867
1128398005466	germination protease; Provisional; Region: PRK12362
1128398005467	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
1128398005468	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cl15768
1128398005469	Uridine kinase [Nucleotide transport and metabolism]; Region: Udk; COG0572
1128398005470	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
1128398005471	active site
1128398005472	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
1128398005473	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
1128398005474	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
1128398005475	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
1128398005476	Competence protein; Region: Competence; pfam03772
1128398005477	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
1128398005478	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398005479	ornithine carbamoyltransferase; Validated; Region: PRK02102
1128398005480	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
1128398005481	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
1128398005482	Hemerythrin; Region: Hemerythrin; cd12107
1128398005483	Fe binding site [ion binding]; other site
1128398005484	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
1128398005485	tetramer interfaces [polypeptide binding]; other site
1128398005486	binuclear metal-binding site [ion binding]; other site
1128398005487	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
1128398005488	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
1128398005489	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
1128398005490	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
1128398005491	ligand binding site [chemical binding]; other site
1128398005492	flexible hinge region; other site
1128398005493	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
1128398005494	non-specific DNA interactions [nucleotide binding]; other site
1128398005495	DNA binding site [nucleotide binding]
1128398005496	sequence specific DNA binding site [nucleotide binding]; other site
1128398005497	putative cAMP binding site [chemical binding]; other site
1128398005498	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398005499	non-specific DNA binding site [nucleotide binding]; other site
1128398005500	salt bridge; other site
1128398005501	sequence-specific DNA binding site [nucleotide binding]; other site
1128398005502	acetylornithine aminotransferase; Provisional; Region: PRK02627
1128398005503	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1128398005504	inhibitor-cofactor binding pocket; inhibition site
1128398005505	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398005506	catalytic residue [active]
1128398005507	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
1128398005508	feedback inhibition sensing region; other site
1128398005509	homohexameric interface [polypeptide binding]; other site
1128398005510	nucleotide binding site [chemical binding]; other site
1128398005511	N-acetyl-L-glutamate binding site [chemical binding]; other site
1128398005512	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398005513	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398005514	Probable transposase; Region: OrfB_IS605; pfam01385
1128398005515	Ribbon-helix-helix domain; Region: RHH_3; pfam12651
1128398005516	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
1128398005517	heterotetramer interface [polypeptide binding]; other site
1128398005518	active site pocket [active]
1128398005519	cleavage site
1128398005520	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
1128398005521	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
1128398005522	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
1128398005523	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398005524	active site
1128398005525	HIGH motif; other site
1128398005526	nucleotide binding site [chemical binding]; other site
1128398005527	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
1128398005528	KMSKS motif; other site
1128398005529	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
1128398005530	hypothetical protein; Provisional; Region: PRK06851
1128398005531	thymidylate kinase; Provisional; Region: PRK13975; cl17243
1128398005532	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1128398005533	ABC-2 type transporter; Region: ABC2_membrane; cl17235
1128398005534	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
1128398005535	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1128398005536	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
1128398005537	HlyD family secretion protein; Region: HlyD_3; pfam13437
1128398005538	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
1128398005539	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1128398005540	MarR family; Region: MarR; pfam01047
1128398005541	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
1128398005542	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
1128398005543	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249
1128398005544	ATP-binding cassette domain of MutS-like homolog; Region: ABC_MutS-like; cd03283
1128398005545	Walker A/P-loop; other site
1128398005546	ATP binding site [chemical binding]; other site
1128398005547	Q-loop/lid; other site
1128398005548	ABC transporter signature motif; other site
1128398005549	Walker B; other site
1128398005550	D-loop; other site
1128398005551	H-loop/switch region; other site
1128398005552	Microcin C7 self-immunity protein determines resistance to exogenous microcin C7; Region: Peptidase_S66_mccF_like; cd07062
1128398005553	putative dimer interface [polypeptide binding]; other site
1128398005554	catalytic triad [active]
1128398005555	Bacillus/Clostridium GerA spore germination protein; Region: GerA; pfam03323
1128398005556	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398005557	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398005558	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
1128398005559	Walker A/P-loop; other site
1128398005560	ATP binding site [chemical binding]; other site
1128398005561	Q-loop/lid; other site
1128398005562	ABC transporter signature motif; other site
1128398005563	Walker B; other site
1128398005564	D-loop; other site
1128398005565	H-loop/switch region; other site
1128398005566	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
1128398005567	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
1128398005568	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398005569	Walker A/P-loop; other site
1128398005570	ATP binding site [chemical binding]; other site
1128398005571	Q-loop/lid; other site
1128398005572	ABC transporter signature motif; other site
1128398005573	Walker B; other site
1128398005574	D-loop; other site
1128398005575	H-loop/switch region; other site
1128398005576	Predicted transcriptional regulators [Transcription]; Region: COG1725
1128398005577	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398005578	DNA-binding site [nucleotide binding]; DNA binding site
1128398005579	ribonuclease Z; Region: RNase_Z; TIGR02651
1128398005580	Predicted ATPase (AAA+ superfamily) [General function prediction only]; Region: COG2607
1128398005581	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398005582	Walker A motif; other site
1128398005583	ATP binding site [chemical binding]; other site
1128398005584	Walker B motif; other site
1128398005585	Predicted membrane protein (DUF2157); Region: DUF2157; pfam09925
1128398005586	GDYXXLXY protein; Region: GDYXXLXY; pfam14345
1128398005587	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
1128398005588	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
1128398005589	ArsC family; Region: ArsC; pfam03960
1128398005590	putative ArsC-like catalytic residues; other site
1128398005591	putative TRX-like catalytic residues [active]
1128398005592	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
1128398005593	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeC; cd03378
1128398005594	active site clefts [active]
1128398005595	zinc binding site [ion binding]; other site
1128398005596	dimer interface [polypeptide binding]; other site
1128398005597	Predicted methyltransferases [General function prediction only]; Region: COG1568
1128398005598	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1128398005599	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398005600	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
1128398005601	Coenzyme A binding pocket [chemical binding]; other site
1128398005602	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1128398005603	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
1128398005604	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398005605	DNA binding residues [nucleotide binding]
1128398005606	Predicted membrane protein [Function unknown]; Region: COG2510
1128398005607	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
1128398005608	conserved repeat domain; Region: B_ant_repeat; TIGR01451
1128398005609	Domain of unknown function DUF11; Region: DUF11; pfam01345
1128398005610	Domain of unknown function DUF11; Region: DUF11; pfam01345
1128398005611	Domain of unknown function DUF11; Region: DUF11; pfam01345
1128398005612	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
1128398005613	Putative cyclase; Region: Cyclase; cl00814
1128398005614	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1128398005615	MarR family; Region: MarR; pfam01047
1128398005616	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398005617	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1128398005618	Coenzyme A binding pocket [chemical binding]; other site
1128398005619	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398005620	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398005621	Walker A/P-loop; other site
1128398005622	ATP binding site [chemical binding]; other site
1128398005623	Q-loop/lid; other site
1128398005624	ABC transporter signature motif; other site
1128398005625	Walker B; other site
1128398005626	D-loop; other site
1128398005627	H-loop/switch region; other site
1128398005628	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398005629	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
1128398005630	dimer interface [polypeptide binding]; other site
1128398005631	phosphorylation site [posttranslational modification]
1128398005632	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398005633	ATP binding site [chemical binding]; other site
1128398005634	Mg2+ binding site [ion binding]; other site
1128398005635	G-X-G motif; other site
1128398005636	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398005637	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398005638	active site
1128398005639	phosphorylation site [posttranslational modification]
1128398005640	intermolecular recognition site; other site
1128398005641	dimerization interface [polypeptide binding]; other site
1128398005642	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398005643	DNA binding site [nucleotide binding]
1128398005644	TraX protein; Region: TraX; pfam05857
1128398005645	conjugal transfer protein TrbP; Provisional; Region: PRK13882
1128398005646	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1128398005647	classical (c) SDRs; Region: SDR_c; cd05233
1128398005648	NAD(P) binding site [chemical binding]; other site
1128398005649	active site
1128398005650	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
1128398005651	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398005652	non-specific DNA binding site [nucleotide binding]; other site
1128398005653	salt bridge; other site
1128398005654	sequence-specific DNA binding site [nucleotide binding]; other site
1128398005655	Cupin domain; Region: Cupin_2; pfam07883
1128398005656	LysE type translocator; Region: LysE; cl00565
1128398005657	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
1128398005658	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
1128398005659	Sodium/hydrogen exchanger family; Region: Na_H_Exchanger; pfam00999
1128398005660	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398005661	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398005662	Protein of unknown function (DUF2785); Region: DUF2785; pfam10978
1128398005663	ATP-binding cassette domain of sbcCD; Region: ABC_sbcCD; cd03279
1128398005664	AAA domain; Region: AAA_23; pfam13476
1128398005665	Walker A/P-loop; other site
1128398005666	ATP binding site [chemical binding]; other site
1128398005667	Q-loop/lid; other site
1128398005668	ABC transporter signature motif; other site
1128398005669	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
1128398005670	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398005671	Q-loop/lid; other site
1128398005672	ABC transporter signature motif; other site
1128398005673	Walker B; other site
1128398005674	D-loop; other site
1128398005675	H-loop/switch region; other site
1128398005676	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1128398005677	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398005678	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398005679	DNA binding residues [nucleotide binding]
1128398005680	Sigma factor regulator C-terminal; Region: Sigma_reg_C; pfam13791
1128398005681	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
1128398005682	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
1128398005683	active site
1128398005684	metal binding site [ion binding]; metal-binding site
1128398005685	DNA binding site [nucleotide binding]
1128398005686	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
1128398005687	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
1128398005688	Part of AAA domain; Region: AAA_19; pfam13245
1128398005689	Family description; Region: UvrD_C_2; pfam13538
1128398005690	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1128398005691	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
1128398005692	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
1128398005693	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1128398005694	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1128398005695	dimer interface [polypeptide binding]; other site
1128398005696	putative functional site; other site
1128398005697	putative MPT binding site; other site
1128398005698	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
1128398005699	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1128398005700	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398005701	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398005702	intersubunit interface [polypeptide binding]; other site
1128398005703	Domain of unknown function (DUF1858); Region: DUF1858; cl14817
1128398005704	Bacterial extracellular solute-binding protein; Region: SBP_bac_6; pfam13343
1128398005705	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
1128398005706	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398005707	Walker A/P-loop; other site
1128398005708	ATP binding site [chemical binding]; other site
1128398005709	Q-loop/lid; other site
1128398005710	ABC transporter signature motif; other site
1128398005711	Walker B; other site
1128398005712	D-loop; other site
1128398005713	H-loop/switch region; other site
1128398005714	Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase [Posttranslational modification, protein turnover, chaperones / Transcription]; Region: HypB; COG0378
1128398005715	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398005716	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398005717	S-adenosylmethionine binding site [chemical binding]; other site
1128398005718	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398005719	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398005720	intersubunit interface [polypeptide binding]; other site
1128398005721	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1128398005722	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005723	FeS/SAM binding site; other site
1128398005724	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398005725	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398005726	S-adenosylmethionine binding site [chemical binding]; other site
1128398005727	Uncharacterized conserved protein [Function unknown]; Region: COG2014
1128398005728	Domain of unknown function (DUF4213); Region: DUF4213; pfam13938
1128398005729	Domain of unknown function (DUF364); Region: DUF364; pfam04016
1128398005730	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398005731	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398005732	intersubunit interface [polypeptide binding]; other site
1128398005733	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1128398005734	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
1128398005735	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398005736	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398005737	Walker A/P-loop; other site
1128398005738	ATP binding site [chemical binding]; other site
1128398005739	Q-loop/lid; other site
1128398005740	ABC transporter signature motif; other site
1128398005741	Walker B; other site
1128398005742	D-loop; other site
1128398005743	H-loop/switch region; other site
1128398005744	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398005745	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398005746	ABC-ATPase subunit  interface; other site
1128398005747	dimer interface [polypeptide binding]; other site
1128398005748	putative PBP binding regions; other site
1128398005749	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398005750	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398005751	intersubunit interface [polypeptide binding]; other site
1128398005752	Domain of unknown function (DUF4213); Region: DUF4213; pfam13938
1128398005753	Domain of unknown function (DUF364); Region: DUF364; pfam04016
1128398005754	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1128398005755	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cd00657
1128398005756	dinuclear metal binding motif [ion binding]; other site
1128398005757	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
1128398005758	Ligand Binding Site [chemical binding]; other site
1128398005759	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1128398005760	MarR family; Region: MarR_2; pfam12802
1128398005761	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1128398005762	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
1128398005763	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
1128398005764	DNA-binding site [nucleotide binding]; DNA binding site
1128398005765	RNA-binding motif; other site
1128398005766	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398005767	dimer interface [polypeptide binding]; other site
1128398005768	phosphorylation site [posttranslational modification]
1128398005769	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398005770	ATP binding site [chemical binding]; other site
1128398005771	Mg2+ binding site [ion binding]; other site
1128398005772	G-X-G motif; other site
1128398005773	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398005774	phosphate regulon transcriptional regulatory protein PhoB; Region: PhoB; TIGR02154
1128398005775	active site
1128398005776	phosphorylation site [posttranslational modification]
1128398005777	intermolecular recognition site; other site
1128398005778	dimerization interface [polypeptide binding]; other site
1128398005779	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398005780	DNA binding site [nucleotide binding]
1128398005781	TIGR03987 family protein; Region: TIGR03987
1128398005782	FMN-binding domain; Region: FMN_bind; cl01081
1128398005783	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
1128398005784	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1128398005785	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
1128398005786	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1128398005787	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1128398005788	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1128398005789	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1128398005790	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1128398005791	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1128398005792	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398005793	guanine deaminase; Region: guan_deamin; TIGR02967
1128398005794	active site
1128398005795	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1128398005796	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
1128398005797	catalytic triad [active]
1128398005798	UDP-N-acetylmuramyl tripeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurE; COG0769
1128398005799	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
1128398005800	Domain of unknown function (DUF1727); Region: DUF1727; pfam08353
1128398005801	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
1128398005802	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
1128398005803	Walker A/P-loop; other site
1128398005804	ATP binding site [chemical binding]; other site
1128398005805	Q-loop/lid; other site
1128398005806	ABC transporter signature motif; other site
1128398005807	Walker B; other site
1128398005808	D-loop; other site
1128398005809	H-loop/switch region; other site
1128398005810	TOBE domain; Region: TOBE_2; pfam08402
1128398005811	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398005812	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
1128398005813	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1128398005814	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005815	dimer interface [polypeptide binding]; other site
1128398005816	conserved gate region; other site
1128398005817	putative PBP binding loops; other site
1128398005818	ABC-ATPase subunit interface; other site
1128398005819	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005820	dimer interface [polypeptide binding]; other site
1128398005821	conserved gate region; other site
1128398005822	ABC-ATPase subunit interface; other site
1128398005823	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1128398005824	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1128398005825	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398005826	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1128398005827	FtsX-like permease family; Region: FtsX; pfam02687
1128398005828	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Region: HATPase_c; pfam02518
1128398005829	ATP binding site [chemical binding]; other site
1128398005830	Mg2+ binding site [ion binding]; other site
1128398005831	G-X-G motif; other site
1128398005832	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
1128398005833	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398005834	active site
1128398005835	phosphorylation site [posttranslational modification]
1128398005836	intermolecular recognition site; other site
1128398005837	dimerization interface [polypeptide binding]; other site
1128398005838	LytTr DNA-binding domain; Region: LytTR; pfam04397
1128398005839	LytTr DNA-binding domain; Region: LytTR; smart00850
1128398005840	Staygreen protein; Region: Staygreen; pfam12638
1128398005841	This putative domain contains a quite highly conserved sequence of CGGC in its central region; Region: CGGC; smart01078
1128398005842	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1128398005843	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398005844	DNA-binding site [nucleotide binding]; DNA binding site
1128398005845	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398005846	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398005847	homodimer interface [polypeptide binding]; other site
1128398005848	catalytic residue [active]
1128398005849	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
1128398005850	putative FMN binding site [chemical binding]; other site
1128398005851	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398005852	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398005853	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1128398005854	dimerization interface [polypeptide binding]; other site
1128398005855	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398005856	Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276
1128398005857	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
1128398005858	G1 box; other site
1128398005859	putative GEF interaction site [polypeptide binding]; other site
1128398005860	GTP/Mg2+ binding site [chemical binding]; other site
1128398005861	Switch I region; other site
1128398005862	G2 box; other site
1128398005863	G3 box; other site
1128398005864	Switch II region; other site
1128398005865	G4 box; other site
1128398005866	G5 box; other site
1128398005867	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
1128398005868	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
1128398005869	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
1128398005870	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
1128398005871	seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474
1128398005872	Selenocysteine synthase [seryl-tRNASer selenium transferase] [Amino acid transport and metabolism]; Region: SelA; COG1921
1128398005873	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398005874	catalytic residue [active]
1128398005875	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
1128398005876	selenophosphate synthetase; Provisional; Region: PRK14105
1128398005877	dimerization interface [polypeptide binding]; other site
1128398005878	putative ATP binding site [chemical binding]; other site
1128398005879	SLBB domain; Region: SLBB; pfam10531
1128398005880	comEA protein; Region: comE; TIGR01259
1128398005881	RelA- and SpoT-like ppGpp Synthetases and Hydrolases, catalytic domain; Region: Rel-Spo_like; cl11966
1128398005882	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
1128398005883	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398005884	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
1128398005885	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
1128398005886	homotrimer interaction site [polypeptide binding]; other site
1128398005887	putative active site [active]
1128398005888	Oligomerisation domain; Region: Oligomerisation; pfam02410
1128398005889	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1128398005890	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398005891	Zn2+ binding site [ion binding]; other site
1128398005892	Mg2+ binding site [ion binding]; other site
1128398005893	nicotinic acid mononucleotide adenylyltransferase; Provisional; Region: nadD; PRK00071
1128398005894	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
1128398005895	active site
1128398005896	(T/H)XGH motif; other site
1128398005897	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
1128398005898	GTPase CgtA; Reviewed; Region: obgE; PRK12297
1128398005899	GTP1/OBG; Region: GTP1_OBG; pfam01018
1128398005900	Obg GTPase; Region: Obg; cd01898
1128398005901	G1 box; other site
1128398005902	GTP/Mg2+ binding site [chemical binding]; other site
1128398005903	Switch I region; other site
1128398005904	G2 box; other site
1128398005905	G3 box; other site
1128398005906	Switch II region; other site
1128398005907	G4 box; other site
1128398005908	G5 box; other site
1128398005909	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
1128398005910	Signal transduction histidine kinase regulating citrate/malate metabolism [Signal transduction mechanisms]; Region: CitA; COG3290
1128398005911	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
1128398005912	Protein of unknown function (DUF464); Region: DUF464; pfam04327
1128398005913	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
1128398005914	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
1128398005915	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
1128398005916	homodimer interface [polypeptide binding]; other site
1128398005917	oligonucleotide binding site [chemical binding]; other site
1128398005918	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
1128398005919	Uncharacterized protein conserved in bacteria (DUF2344); Region: DUF2344; pfam10105
1128398005920	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
1128398005921	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398005922	FeS/SAM binding site; other site
1128398005923	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1128398005924	Peptidase family M23; Region: Peptidase_M23; pfam01551
1128398005925	cell division topological specificity factor MinE; Provisional; Region: PRK13987
1128398005926	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
1128398005927	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
1128398005928	Switch I; other site
1128398005929	Switch II; other site
1128398005930	septum formation inhibitor; Reviewed; Region: minC; PRK00513
1128398005931	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
1128398005932	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
1128398005933	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1128398005934	EamA-like transporter family; Region: EamA; pfam00892
1128398005935	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
1128398005936	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398005937	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398005938	Walker A/P-loop; other site
1128398005939	ATP binding site [chemical binding]; other site
1128398005940	Q-loop/lid; other site
1128398005941	ABC transporter signature motif; other site
1128398005942	Walker B; other site
1128398005943	D-loop; other site
1128398005944	H-loop/switch region; other site
1128398005945	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398005946	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398005947	FtsX-like permease family; Region: FtsX; pfam02687
1128398005948	NMT1-like family; Region: NMT1_2; pfam13379
1128398005949	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1128398005950	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398005951	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398005952	Walker A/P-loop; other site
1128398005953	ATP binding site [chemical binding]; other site
1128398005954	Q-loop/lid; other site
1128398005955	ABC transporter signature motif; other site
1128398005956	Walker B; other site
1128398005957	D-loop; other site
1128398005958	H-loop/switch region; other site
1128398005959	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398005960	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398005961	dimer interface [polypeptide binding]; other site
1128398005962	conserved gate region; other site
1128398005963	putative PBP binding loops; other site
1128398005964	ABC-ATPase subunit interface; other site
1128398005965	Domain of unknown function (DUF4418); Region: DUF4418; pfam14387
1128398005966	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
1128398005967	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398005968	putative substrate translocation pore; other site
1128398005969	hybrid cluster protein; Provisional; Region: PRK05290
1128398005970	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398005971	ACS interaction site; other site
1128398005972	CODH interaction site; other site
1128398005973	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398005974	ACS interaction site; other site
1128398005975	CODH interaction site; other site
1128398005976	metal cluster binding site [ion binding]; other site
1128398005977	Predicted membrane protein [Function unknown]; Region: COG4905
1128398005978	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
1128398005979	Predicted inorganic polyphosphate/ATP-NAD kinase [General function prediction only]; Region: COG3199
1128398005980	ATP-NAD kinase; Region: NAD_kinase; pfam01513
1128398005981	Zinc dependent phospholipase C (alpha toxin); Region: Zn_dep_PLPC; cd11009
1128398005982	Zn binding site [ion binding]; other site
1128398005983	peptidase T; Region: peptidase-T; TIGR01882
1128398005984	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
1128398005985	metal binding site [ion binding]; metal-binding site
1128398005986	dimer interface [polypeptide binding]; other site
1128398005987	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
1128398005988	classical (c) SDRs; Region: SDR_c; cd05233
1128398005989	NAD(P) binding site [chemical binding]; other site
1128398005990	active site
1128398005991	VanZ like family; Region: VanZ; cl01971
1128398005992	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398005993	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1128398005994	4Fe-4S binding domain; Region: Fer4_5; pfam12801
1128398005995	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1128398005996	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1128398005997	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1128398005998	catalytic residues [active]
1128398005999	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
1128398006000	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
1128398006001	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006002	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006003	dimer interface [polypeptide binding]; other site
1128398006004	phosphorylation site [posttranslational modification]
1128398006005	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006006	ATP binding site [chemical binding]; other site
1128398006007	Mg2+ binding site [ion binding]; other site
1128398006008	G-X-G motif; other site
1128398006009	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398006010	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006011	active site
1128398006012	phosphorylation site [posttranslational modification]
1128398006013	intermolecular recognition site; other site
1128398006014	dimerization interface [polypeptide binding]; other site
1128398006015	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398006016	DNA binding site [nucleotide binding]
1128398006017	Predicted membrane protein [Function unknown]; Region: COG1971
1128398006018	Domain of unknown function DUF; Region: DUF204; pfam02659
1128398006019	Domain of unknown function DUF; Region: DUF204; pfam02659
1128398006020	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cl17270
1128398006021	Phosphotransferase enzyme family; Region: APH; pfam01636
1128398006022	active site
1128398006023	ATP binding site [chemical binding]; other site
1128398006024	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1128398006025	substrate binding site [chemical binding]; other site
1128398006026	Predicted RNA-binding protein, contains TRAM domain [General function prediction only]; Region: COG3269
1128398006027	23S rRNA (uracil-5-)-methyltransferase RumA; Region: rumA; TIGR00479
1128398006028	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398006029	S-adenosylmethionine binding site [chemical binding]; other site
1128398006030	Protein of unknown function (DUF2798); Region: DUF2798; pfam11391
1128398006031	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
1128398006032	active site
1128398006033	pyruvate kinase; Provisional; Region: PRK06354
1128398006034	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
1128398006035	domain interfaces; other site
1128398006036	active site
1128398006037	Phosphohistidine swiveling domain [Signal transduction mechanisms]; Region: COG3848
1128398006038	6-phosphofructokinase; Provisional; Region: PRK03202
1128398006039	6-phosphofructokinase; Region: PFKA_ATP; TIGR02482
1128398006040	active site
1128398006041	ADP/pyrophosphate binding site [chemical binding]; other site
1128398006042	dimerization interface [polypeptide binding]; other site
1128398006043	allosteric effector site; other site
1128398006044	fructose-1,6-bisphosphate binding site; other site
1128398006045	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826
1128398006046	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
1128398006047	active site
1128398006048	PHP Thumb interface [polypeptide binding]; other site
1128398006049	metal binding site [ion binding]; metal-binding site
1128398006050	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
1128398006051	generic binding surface II; other site
1128398006052	generic binding surface I; other site
1128398006053	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
1128398006054	dimerization domain swap beta strand [polypeptide binding]; other site
1128398006055	regulatory protein interface [polypeptide binding]; other site
1128398006056	active site
1128398006057	regulatory phosphorylation site [posttranslational modification]; other site
1128398006058	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
1128398006059	Sporulation Regulator WhiA N terminal; Region: WhiA_N; pfam10298
1128398006060	Class I aldolases; Region: Aldolase_Class_I; cl17187
1128398006061	KDPG and KHG aldolase; Region: Aldolase; cl17259
1128398006062	conserved hypothetical protein, cofD-related; Region: CofD_related; TIGR01826
1128398006063	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
1128398006064	phosphate binding site [ion binding]; other site
1128398006065	putative substrate binding pocket [chemical binding]; other site
1128398006066	dimer interface [polypeptide binding]; other site
1128398006067	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
1128398006068	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
1128398006069	Histidinol phosphatase and related hydrolases of the PHP family [Amino acid transport and metabolism / General function prediction only]; Region: HIS2; COG1387
1128398006070	active site
1128398006071	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
1128398006072	FAD binding domain; Region: FAD_binding_4; pfam01565
1128398006073	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
1128398006074	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1128398006075	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
1128398006076	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398006077	dimerization interface [polypeptide binding]; other site
1128398006078	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006079	dimer interface [polypeptide binding]; other site
1128398006080	Methyl-accepting chemotaxis protein (MCP) signalling domain; Region: MCPsignal; pfam00015
1128398006081	putative CheW interface [polypeptide binding]; other site
1128398006082	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398006083	dimerization interface [polypeptide binding]; other site
1128398006084	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398006085	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006086	dimer interface [polypeptide binding]; other site
1128398006087	putative CheW interface [polypeptide binding]; other site
1128398006088	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1128398006089	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1128398006090	dimer interface [polypeptide binding]; other site
1128398006091	PYR/PP interface [polypeptide binding]; other site
1128398006092	TPP binding site [chemical binding]; other site
1128398006093	substrate binding site [chemical binding]; other site
1128398006094	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1128398006095	Domain of unknown function; Region: EKR; smart00890
1128398006096	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398006097	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1128398006098	TPP-binding site [chemical binding]; other site
1128398006099	dimer interface [polypeptide binding]; other site
1128398006100	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
1128398006101	Hpr(Ser) kinase/phosphatase; Region: hpr-ser; TIGR00679
1128398006102	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
1128398006103	Hpr binding site; other site
1128398006104	active site
1128398006105	homohexamer subunit interaction site [polypeptide binding]; other site
1128398006106	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
1128398006107	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1128398006108	GIY-YIG motif/motif A; other site
1128398006109	active site
1128398006110	catalytic site [active]
1128398006111	putative DNA binding site [nucleotide binding]; other site
1128398006112	metal binding site [ion binding]; metal-binding site
1128398006113	UvrB/uvrC motif; Region: UVR; pfam02151
1128398006114	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
1128398006115	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
1128398006116	DNA binding site [nucleotide binding]
1128398006117	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
1128398006118	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1128398006119	FMN binding site [chemical binding]; other site
1128398006120	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
1128398006121	FMN binding site [chemical binding]; other site
1128398006122	dimer interface [polypeptide binding]; other site
1128398006123	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1128398006124	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398006125	Coenzyme A binding pocket [chemical binding]; other site
1128398006126	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398006127	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398006128	S-adenosylmethionine binding site [chemical binding]; other site
1128398006129	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1128398006130	active site
1128398006131	Protein of unknown function (DUF2809); Region: DUF2809; pfam10990
1128398006132	Uncharacterized conserved protein (DUF2164); Region: DUF2164; cl02278
1128398006133	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1128398006134	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
1128398006135	Phosphotransferase enzyme family; Region: APH; pfam01636
1128398006136	active site
1128398006137	substrate binding site [chemical binding]; other site
1128398006138	ATP binding site [chemical binding]; other site
1128398006139	SMI1 / KNR4 family (SUKH-1); Region: SMI1_KNR4; pfam09346
1128398006140	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_17; cd04676
1128398006141	nudix motif; other site
1128398006142	RNA polymerase factor sigma-70; Validated; Region: PRK06811
1128398006143	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398006144	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1128398006145	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
1128398006146	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1128398006147	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
1128398006148	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
1128398006149	excinuclease ABC subunit B; Provisional; Region: PRK05298
1128398006150	Myosin and Kinesin motor domain. These ATPases belong to the P-loop NTPase family and provide the driving force in myosin and kinesin mediated processes; Region: Motor_domain; cl00286
1128398006151	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1128398006152	ATP-binding site [chemical binding]; other site
1128398006153	ATP binding site [chemical binding]; other site
1128398006154	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398006155	nucleotide binding region [chemical binding]; other site
1128398006156	ATP-binding site [chemical binding]; other site
1128398006157	Ultra-violet resistance protein B; Region: UvrB; pfam12344
1128398006158	UvrB/uvrC motif; Region: UVR; pfam02151
1128398006159	Dipeptidyl peptidase IV (DPP IV) N-terminal region; Region: DPPIV_N; pfam00930
1128398006160	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1128398006161	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
1128398006162	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
1128398006163	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
1128398006164	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
1128398006165	protein binding site [polypeptide binding]; other site
1128398006166	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
1128398006167	Catalytic dyad [active]
1128398006168	Membrane-bound metallopeptidase [Cell division and chromosome partitioning]; Region: COG4942
1128398006169	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
1128398006170	Peptidase family M23; Region: Peptidase_M23; pfam01551
1128398006171	Cell division protein [Cell division and chromosome partitioning]; Region: FtsX; COG2177
1128398006172	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
1128398006173	Predicted ATPase involved in cell division [Cell division and chromosome partitioning]; Region: FtsE; COG2884
1128398006174	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398006175	Walker A/P-loop; other site
1128398006176	ATP binding site [chemical binding]; other site
1128398006177	Q-loop/lid; other site
1128398006178	ABC transporter signature motif; other site
1128398006179	Walker B; other site
1128398006180	D-loop; other site
1128398006181	H-loop/switch region; other site
1128398006182	Predicted membrane protein [Function unknown]; Region: COG3462
1128398006183	Short C-terminal domain; Region: SHOCT; pfam09851
1128398006184	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398006185	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006186	active site
1128398006187	phosphorylation site [posttranslational modification]
1128398006188	intermolecular recognition site; other site
1128398006189	dimerization interface [polypeptide binding]; other site
1128398006190	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398006191	DNA binding site [nucleotide binding]
1128398006192	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006193	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398006194	dimerization interface [polypeptide binding]; other site
1128398006195	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006196	dimer interface [polypeptide binding]; other site
1128398006197	phosphorylation site [posttranslational modification]
1128398006198	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006199	ATP binding site [chemical binding]; other site
1128398006200	Mg2+ binding site [ion binding]; other site
1128398006201	G-X-G motif; other site
1128398006202	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
1128398006203	metal-binding site [ion binding]
1128398006204	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1128398006205	Family description; Region: DsbD_2; pfam13386
1128398006206	Plastocyanin domain containing protein [General function prediction only]; Region: COG4633
1128398006207	Cupredoxin-like domain; Region: Cupredoxin_1; cl17234
1128398006208	OsmC-like protein; Region: OsmC; pfam02566
1128398006209	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398006210	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006211	dimer interface [polypeptide binding]; other site
1128398006212	phosphorylation site [posttranslational modification]
1128398006213	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006214	ATP binding site [chemical binding]; other site
1128398006215	Mg2+ binding site [ion binding]; other site
1128398006216	G-X-G motif; other site
1128398006217	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398006218	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006219	active site
1128398006220	phosphorylation site [posttranslational modification]
1128398006221	intermolecular recognition site; other site
1128398006222	dimerization interface [polypeptide binding]; other site
1128398006223	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398006224	DNA binding site [nucleotide binding]
1128398006225	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
1128398006226	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
1128398006227	AAA domain; Region: AAA_32; pfam13654
1128398006228	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1128398006229	PrcB C-terminal; Region: PrcB_C; pfam14343
1128398006230	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
1128398006231	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
1128398006232	PYR/PP interface [polypeptide binding]; other site
1128398006233	dimer interface [polypeptide binding]; other site
1128398006234	TPP binding site [chemical binding]; other site
1128398006235	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
1128398006236	transketolase; Reviewed; Region: PRK05899
1128398006237	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
1128398006238	TPP-binding site [chemical binding]; other site
1128398006239	dimer interface [polypeptide binding]; other site
1128398006240	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1128398006241	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398006242	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1128398006243	Teichoic acid biosynthesis proteins [Cell envelope biogenesis, outer membrane]; Region: WecG; COG1922
1128398006244	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
1128398006245	polysaccharide pyruvyl transferase CsaB; Region: S_layer_CsaB; TIGR03609
1128398006246	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398006247	PemK-like protein; Region: PemK; pfam02452
1128398006248	Uncharacterized protein family (UPF0156); Region: RHH_2; cl17383
1128398006249	alanine racemase; Reviewed; Region: alr; PRK00053
1128398006250	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
1128398006251	active site
1128398006252	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
1128398006253	dimer interface [polypeptide binding]; other site
1128398006254	substrate binding site [chemical binding]; other site
1128398006255	catalytic residues [active]
1128398006256	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
1128398006257	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
1128398006258	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
1128398006259	putative substrate binding site [chemical binding]; other site
1128398006260	putative ATP binding site [chemical binding]; other site
1128398006261	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
1128398006262	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
1128398006263	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
1128398006264	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
1128398006265	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
1128398006266	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
1128398006267	dimer interface [polypeptide binding]; other site
1128398006268	active site
1128398006269	YibE/F-like protein; Region: YibE_F; pfam07907
1128398006270	Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]; Region: MetC; COG0626
1128398006271	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1128398006272	homodimer interface [polypeptide binding]; other site
1128398006273	substrate-cofactor binding pocket; other site
1128398006274	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398006275	catalytic residue [active]
1128398006276	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
1128398006277	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
1128398006278	active site
1128398006279	putative substrate binding pocket [chemical binding]; other site
1128398006280	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
1128398006281	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
1128398006282	Predicted periplasmic ligand-binding sensor domain [Signal transduction mechanisms]; Region: COG3292
1128398006283	Two component regulator propeller; Region: Reg_prop; pfam07494
1128398006284	Two component regulator propeller; Region: Reg_prop; pfam07494
1128398006285	Two component regulator propeller; Region: Reg_prop; pfam07494
1128398006286	Y_Y_Y domain; Region: Y_Y_Y; pfam07495
1128398006287	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006288	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006289	dimer interface [polypeptide binding]; other site
1128398006290	phosphorylation site [posttranslational modification]
1128398006291	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006292	ATP binding site [chemical binding]; other site
1128398006293	Mg2+ binding site [ion binding]; other site
1128398006294	G-X-G motif; other site
1128398006295	The GH18 (glycosyl hydrolase, family 18) type II chitinases hydrolyze chitin, an abundant polymer of beta-1,4-linked N-acetylglucosamine (GlcNAc) which is a major component of the cell wall of fungi and the exoskeleton of arthropods.  Chitinases have...; Region: GH18_chitinase-like; cl10447
1128398006296	active site
1128398006297	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
1128398006298	PilZ domain; Region: PilZ; pfam07238
1128398006299	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
1128398006300	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
1128398006301	DXD motif; other site
1128398006302	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1128398006303	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1128398006304	NodB motif; other site
1128398006305	active site
1128398006306	metal binding site [ion binding]; metal-binding site
1128398006307	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1128398006308	NodB motif; other site
1128398006309	active site
1128398006310	catalytic site [active]
1128398006311	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1128398006312	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1128398006313	NodB motif; other site
1128398006314	active site
1128398006315	catalytic site [active]
1128398006316	metal binding site [ion binding]; metal-binding site
1128398006317	UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: WecC; COG0677
1128398006318	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
1128398006319	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
1128398006320	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl17736
1128398006321	active site
1128398006322	dimerization interface [polypeptide binding]; other site
1128398006323	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398006324	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398006325	metal binding site [ion binding]; metal-binding site
1128398006326	active site
1128398006327	I-site; other site
1128398006328	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1128398006329	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398006330	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006331	dimer interface [polypeptide binding]; other site
1128398006332	putative CheW interface [polypeptide binding]; other site
1128398006333	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1128398006334	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1128398006335	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006336	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006337	dimer interface [polypeptide binding]; other site
1128398006338	phosphorylation site [posttranslational modification]
1128398006339	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006340	ATP binding site [chemical binding]; other site
1128398006341	Mg2+ binding site [ion binding]; other site
1128398006342	G-X-G motif; other site
1128398006343	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398006344	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006345	active site
1128398006346	phosphorylation site [posttranslational modification]
1128398006347	intermolecular recognition site; other site
1128398006348	dimerization interface [polypeptide binding]; other site
1128398006349	Histidine kinase; Region: His_kinase; pfam06580
1128398006350	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006351	ATP binding site [chemical binding]; other site
1128398006352	Mg2+ binding site [ion binding]; other site
1128398006353	G-X-G motif; other site
1128398006354	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398006355	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398006356	Probable transposase; Region: OrfB_IS605; pfam01385
1128398006357	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398006358	Response regulator containing CheY-like receiver and SARP domains [Signal transduction mechanisms]; Region: COG3947
1128398006359	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006360	active site
1128398006361	phosphorylation site [posttranslational modification]
1128398006362	intermolecular recognition site; other site
1128398006363	dimerization interface [polypeptide binding]; other site
1128398006364	Transcriptional regulatory protein, C terminal; Region: Trans_reg_C; smart00862
1128398006365	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
1128398006366	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; pfam07695
1128398006367	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006368	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006369	dimer interface [polypeptide binding]; other site
1128398006370	phosphorylation site [posttranslational modification]
1128398006371	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006372	ATP binding site [chemical binding]; other site
1128398006373	Mg2+ binding site [ion binding]; other site
1128398006374	G-X-G motif; other site
1128398006375	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398006376	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006377	active site
1128398006378	phosphorylation site [posttranslational modification]
1128398006379	intermolecular recognition site; other site
1128398006380	dimerization interface [polypeptide binding]; other site
1128398006381	Histidine kinase; Region: His_kinase; pfam06580
1128398006382	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006383	Mg2+ binding site [ion binding]; other site
1128398006384	G-X-G motif; other site
1128398006385	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
1128398006386	catalytic center binding site [active]
1128398006387	ATP binding site [chemical binding]; other site
1128398006388	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
1128398006389	homooctamer interface [polypeptide binding]; other site
1128398006390	active site
1128398006391	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
1128398006392	dihydropteroate synthase; Region: DHPS; TIGR01496
1128398006393	substrate binding pocket [chemical binding]; other site
1128398006394	dimer interface [polypeptide binding]; other site
1128398006395	inhibitor binding site; inhibition site
1128398006396	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
1128398006397	homodecamer interface [polypeptide binding]; other site
1128398006398	GTP cyclohydrolase I; Provisional; Region: PLN03044
1128398006399	active site
1128398006400	putative catalytic site residues [active]
1128398006401	zinc binding site [ion binding]; other site
1128398006402	GTP-CH-I/GFRP interaction surface; other site
1128398006403	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
1128398006404	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
1128398006405	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398006406	catalytic residue [active]
1128398006407	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
1128398006408	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
1128398006409	chorismate binding enzyme; Region: Chorismate_bind; cl10555
1128398006410	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
1128398006411	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
1128398006412	glutamine binding [chemical binding]; other site
1128398006413	catalytic triad [active]
1128398006414	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
1128398006415	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cl12060
1128398006416	Metal-binding active site; metal-binding site
1128398006417	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1128398006418	ABC exporter membrane fusion protein, DevB family; Region: heterocyst_DevB; TIGR02971
1128398006419	HlyD family secretion protein; Region: HlyD_3; pfam13437
1128398006420	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398006421	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398006422	Walker A/P-loop; other site
1128398006423	ATP binding site [chemical binding]; other site
1128398006424	Q-loop/lid; other site
1128398006425	ABC transporter signature motif; other site
1128398006426	Walker B; other site
1128398006427	D-loop; other site
1128398006428	H-loop/switch region; other site
1128398006429	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398006430	FtsX-like permease family; Region: FtsX; pfam02687
1128398006431	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398006432	FtsX-like permease family; Region: FtsX; pfam02687
1128398006433	LysE type translocator; Region: LysE; cl00565
1128398006434	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1128398006435	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398006436	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398006437	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
1128398006438	Protein of unknown function (DUF3036); Region: DUF3036; pfam11234
1128398006439	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398006440	salt bridge; other site
1128398006441	non-specific DNA binding site [nucleotide binding]; other site
1128398006442	sequence-specific DNA binding site [nucleotide binding]; other site
1128398006443	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1128398006444	RNA polymerase factor sigma-70; Validated; Region: PRK06811
1128398006445	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398006446	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398006447	DNA binding residues [nucleotide binding]
1128398006448	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398006449	putative substrate translocation pore; other site
1128398006450	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
1128398006451	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
1128398006452	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
1128398006453	active site
1128398006454	catalytic site [active]
1128398006455	substrate binding site [chemical binding]; other site
1128398006456	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
1128398006457	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
1128398006458	HIGH motif; other site
1128398006459	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
1128398006460	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398006461	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
1128398006462	active site
1128398006463	KMSKS motif; other site
1128398006464	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
1128398006465	tRNA binding surface [nucleotide binding]; other site
1128398006466	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
1128398006467	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1128398006468	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
1128398006469	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398006470	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1128398006471	Walker A/P-loop; other site
1128398006472	ATP binding site [chemical binding]; other site
1128398006473	Q-loop/lid; other site
1128398006474	ABC transporter signature motif; other site
1128398006475	Walker B; other site
1128398006476	D-loop; other site
1128398006477	H-loop/switch region; other site
1128398006478	Predicted transcriptional regulators [Transcription]; Region: COG1725
1128398006479	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398006480	DNA-binding site [nucleotide binding]; DNA binding site
1128398006481	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
1128398006482	ApbE family; Region: ApbE; pfam02424
1128398006483	Domain of unknown function (DUF3787); Region: DUF3787; pfam12655
1128398006484	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
1128398006485	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
1128398006486	dimer interface [polypeptide binding]; other site
1128398006487	PYR/PP interface [polypeptide binding]; other site
1128398006488	TPP binding site [chemical binding]; other site
1128398006489	substrate binding site [chemical binding]; other site
1128398006490	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
1128398006491	Domain of unknown function; Region: EKR; smart00890
1128398006492	4Fe-4S binding domain; Region: Fer4_6; pfam12837
1128398006493	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398006494	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
1128398006495	TPP-binding site [chemical binding]; other site
1128398006496	dimer interface [polypeptide binding]; other site
1128398006497	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
1128398006498	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
1128398006499	DNA-binding site [nucleotide binding]; DNA binding site
1128398006500	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398006501	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398006502	homodimer interface [polypeptide binding]; other site
1128398006503	catalytic residue [active]
1128398006504	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cl00246
1128398006505	FAD binding site [chemical binding]; other site
1128398006506	MoCF_BD: molybdenum cofactor (MoCF) binding domain (BD). This domain is found a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. The domain is presumed to bind molybdopterin; Region: MoCF_BD; cl00451
1128398006507	MPT binding site; other site
1128398006508	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
1128398006509	MutS domain III; Region: MutS_III; pfam05192
1128398006510	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398006511	AAA domain; Region: AAA_21; pfam13304
1128398006512	Walker A/P-loop; other site
1128398006513	ATP binding site [chemical binding]; other site
1128398006514	Q-loop/lid; other site
1128398006515	ABC transporter signature motif; other site
1128398006516	Walker B; other site
1128398006517	D-loop; other site
1128398006518	H-loop/switch region; other site
1128398006519	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
1128398006520	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398006521	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398006522	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
1128398006523	putative dimerization interface [polypeptide binding]; other site
1128398006524	Predicted membrane protein [Function unknown]; Region: COG2855
1128398006525	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398006526	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398006527	dimerization interface [polypeptide binding]; other site
1128398006528	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398006529	dimer interface [polypeptide binding]; other site
1128398006530	phosphorylation site [posttranslational modification]
1128398006531	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398006532	ATP binding site [chemical binding]; other site
1128398006533	Mg2+ binding site [ion binding]; other site
1128398006534	G-X-G motif; other site
1128398006535	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398006536	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398006537	active site
1128398006538	phosphorylation site [posttranslational modification]
1128398006539	intermolecular recognition site; other site
1128398006540	dimerization interface [polypeptide binding]; other site
1128398006541	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398006542	DNA binding site [nucleotide binding]
1128398006543	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1128398006544	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398006545	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006546	dimer interface [polypeptide binding]; other site
1128398006547	putative CheW interface [polypeptide binding]; other site
1128398006548	Predicted ATPases of PP-loop superfamily [General function prediction only]; Region: COG2102
1128398006549	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
1128398006550	Ligand Binding Site [chemical binding]; other site
1128398006551	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK14869
1128398006552	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cl15354
1128398006553	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
1128398006554	DRTGG domain; Region: DRTGG; pfam07085
1128398006555	Domain in cystathionine beta-synthase and other proteins; Region: CBS; smart00116
1128398006556	DHHA2 domain; Region: DHHA2; pfam02833
1128398006557	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
1128398006558	MgtE intracellular N domain; Region: MgtE_N; smart00924
1128398006559	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
1128398006560	Divalent cation transporter; Region: MgtE; pfam01769
1128398006561	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
1128398006562	Domain of unknown function DUF; Region: DUF204; pfam02659
1128398006563	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
1128398006564	ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and...; Region: modD_like; cd01573
1128398006565	dimerization interface [polypeptide binding]; other site
1128398006566	active site
1128398006567	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398006568	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cl00107
1128398006569	Glycosyl hydrolase family 26; Region: Glyco_hydro_26; pfam02156
1128398006570	Mg2+ and Co2+ transporters [Inorganic ion transport and metabolism]; Region: CorA; COG0598
1128398006571	Thermotoga maritima CorA_like subfamily; Region: TmCorA-like_1; cd12828
1128398006572	oligomer interface [polypeptide binding]; other site
1128398006573	metal binding site [ion binding]; metal-binding site
1128398006574	metal binding site [ion binding]; metal-binding site
1128398006575	Cl binding site [ion binding]; other site
1128398006576	aspartate ring; other site
1128398006577	basic sphincter; other site
1128398006578	putative hydrophobic gate; other site
1128398006579	periplasmic entrance; other site
1128398006580	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
1128398006581	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
1128398006582	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398006583	dimer interface [polypeptide binding]; other site
1128398006584	conserved gate region; other site
1128398006585	ABC-ATPase subunit interface; other site
1128398006586	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
1128398006587	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1128398006588	Walker A/P-loop; other site
1128398006589	ATP binding site [chemical binding]; other site
1128398006590	Q-loop/lid; other site
1128398006591	ABC transporter signature motif; other site
1128398006592	Walker B; other site
1128398006593	D-loop; other site
1128398006594	H-loop/switch region; other site
1128398006595	O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]; Region: MET17; COG2873
1128398006596	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
1128398006597	homodimer interface [polypeptide binding]; other site
1128398006598	substrate-cofactor binding pocket; other site
1128398006599	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398006600	catalytic residue [active]
1128398006601	Nitrogenase_vnfN_like: VnfN subunit of the VnfEN complex-like.  This group in addition to VnfN contains a subset of the beta subunit of the nitrogenase MoFe protein and NifN-like proteins. The nitrogenase enzyme system catalyzes the ATP-dependent...; Region: Nitrogenase_VnfN_like; cd01971
1128398006602	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398006603	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1128398006604	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398006605	NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the...; Region: NifH; cd02040
1128398006606	nitrogenase iron protein; Region: nifH; TIGR01287
1128398006607	Nucleotide-binding sites [chemical binding]; other site
1128398006608	Walker A motif; other site
1128398006609	Switch I region of nucleotide binding site; other site
1128398006610	Fe4S4 binding sites [ion binding]; other site
1128398006611	Switch II region of nucleotide binding site; other site
1128398006612	This CD represents a family of iron-molybdenum cluster-binding proteins that includes NifB, NifX, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme.  This...; Region: NifX_NifB; cl00252
1128398006613	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398006614	Radical SAM superfamily; Region: Radical_SAM; pfam04055
1128398006615	FeS/SAM binding site; other site
1128398006616	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1128398006617	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398006618	The nitrogenase enzyme system catalyzes the ATP-dependent reduction of dinitrogen to ammonia.  This group contains both alpha and beta subunits of component 1 of the three known genetically distinct types of nitrogenase systems: a molybdenum-dependent; Region: Oxidoreductase_nitrogenase; cl02775
1128398006619	Nitrogenase component 1 type Oxidoreductase; Region: Oxidored_nitro; pfam00148
1128398006620	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398006621	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398006622	Walker A/P-loop; other site
1128398006623	ATP binding site [chemical binding]; other site
1128398006624	Q-loop/lid; other site
1128398006625	ABC transporter signature motif; other site
1128398006626	Walker B; other site
1128398006627	D-loop; other site
1128398006628	H-loop/switch region; other site
1128398006629	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398006630	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398006631	dimer interface [polypeptide binding]; other site
1128398006632	conserved gate region; other site
1128398006633	putative PBP binding loops; other site
1128398006634	ABC-ATPase subunit interface; other site
1128398006635	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
1128398006636	NMT1-like family; Region: NMT1_2; pfam13379
1128398006637	Cysteine synthase [Amino acid transport and metabolism]; Region: CysK; COG0031
1128398006638	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
1128398006639	dimer interface [polypeptide binding]; other site
1128398006640	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398006641	catalytic residue [active]
1128398006642	bifunctional glutamate--cysteine ligase/glutathione synthetase; Provisional; Region: PRK02471
1128398006643	Glutamate-cysteine ligase; Region: Glu_cys_ligase; cl17352
1128398006644	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1128398006645	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1128398006646	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
1128398006647	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
1128398006648	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
1128398006649	putative active site [active]
1128398006650	catalytic site [active]
1128398006651	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
1128398006652	putative active site [active]
1128398006653	catalytic site [active]
1128398006654	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398006655	zinc transporter ZupT; Provisional; Region: PRK04201
1128398006656	Protein of unknown function (DUF2884); Region: DUF2884; pfam11101
1128398006657	Allophanate hydrolase subunit 2; Region: AHS2; pfam02626
1128398006658	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
1128398006659	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
1128398006660	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
1128398006661	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
1128398006662	putative active site [active]
1128398006663	Pyruvate kinase, alpha/beta domain; Region: PK_C; pfam02887
1128398006664	Nitroreductase-like family 4.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_4; cd02140
1128398006665	dimer interface [polypeptide binding]; other site
1128398006666	FMN binding site [chemical binding]; other site
1128398006667	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398006668	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398006669	metal binding site [ion binding]; metal-binding site
1128398006670	active site
1128398006671	I-site; other site
1128398006672	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398006673	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
1128398006674	putative active site [active]
1128398006675	heme pocket [chemical binding]; other site
1128398006676	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cl02459
1128398006677	putative active site [active]
1128398006678	heme pocket [chemical binding]; other site
1128398006679	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
1128398006680	Domain of unknown function DUF21; Region: DUF21; pfam01595
1128398006681	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
1128398006682	Transporter associated domain; Region: CorC_HlyC; pfam03471
1128398006683	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
1128398006684	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
1128398006685	glutaminase active site [active]
1128398006686	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
1128398006687	dimer interface [polypeptide binding]; other site
1128398006688	active site
1128398006689	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
1128398006690	dimer interface [polypeptide binding]; other site
1128398006691	active site
1128398006692	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006693	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398006694	dimer interface [polypeptide binding]; other site
1128398006695	putative CheW interface [polypeptide binding]; other site
1128398006696	MCP-signal associated domain; Region: MCPsignal_assoc; pfam13682
1128398006697	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
1128398006698	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
1128398006699	active site
1128398006700	substrate binding site [chemical binding]; other site
1128398006701	metal binding site [ion binding]; metal-binding site
1128398006702	Uncharacterized conserved protein [Function unknown]; Region: COG1284
1128398006703	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398006704	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398006705	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
1128398006706	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
1128398006707	YbbR-like protein; Region: YbbR; pfam07949
1128398006708	TIGR00159 family protein; Region: TIGR00159
1128398006709	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1128398006710	Protease prsW family; Region: PrsW-protease; pfam13367
1128398006711	Rubrerythrin [Energy production and conversion]; Region: COG1592
1128398006712	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
1128398006713	binuclear metal center [ion binding]; other site
1128398006714	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
1128398006715	iron binding site [ion binding]; other site
1128398006716	CotJB protein; Region: CotJB; pfam12652
1128398006717	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1128398006718	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
1128398006719	active site
1128398006720	conformational flexibility of ligand binding pocket; other site
1128398006721	ADP-ribosylating toxin turn-turn motif; other site
1128398006722	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
1128398006723	amidase catalytic site [active]
1128398006724	Zn binding residues [ion binding]; other site
1128398006725	substrate binding site [chemical binding]; other site
1128398006726	Protein of unknown function (DUF2762); Region: DUF2762; pfam10960
1128398006727	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
1128398006728	Bacterial PH domain; Region: DUF304; pfam03703
1128398006729	Recombination protein U; Region: RecU; cl01314
1128398006730	Replication initiation and membrane attachment; Region: DnaB_2; cl12121
1128398006731	Helix-turn-helix domain; Region: HTH_36; pfam13730
1128398006732	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
1128398006733	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398006734	non-specific DNA binding site [nucleotide binding]; other site
1128398006735	salt bridge; other site
1128398006736	sequence-specific DNA binding site [nucleotide binding]; other site
1128398006737	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1128398006738	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
1128398006739	catalytic residues [active]
1128398006740	catalytic nucleophile [active]
1128398006741	Recombinase; Region: Recombinase; pfam07508
1128398006742	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1128398006743	Ferritin-like superfamily of diiron-containing four-helix-bundle proteins; Region: Ferritin_like; cl00264
1128398006744	dinuclear metal binding motif [ion binding]; other site
1128398006745	FeoA domain; Region: FeoA; pfam04023
1128398006746	Ferrous iron transport protein B; Region: FeoB_N; pfam02421
1128398006747	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1128398006748	G1 box; other site
1128398006749	GTP/Mg2+ binding site [chemical binding]; other site
1128398006750	Switch I region; other site
1128398006751	G2 box; other site
1128398006752	G3 box; other site
1128398006753	Switch II region; other site
1128398006754	G4 box; other site
1128398006755	G5 box; other site
1128398006756	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1128398006757	Nucleoside recognition; Region: Gate; pfam07670
1128398006758	Nucleoside recognition; Region: Gate; pfam07670
1128398006759	manganese transport transcriptional regulator; Provisional; Region: PRK03902
1128398006760	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
1128398006761	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
1128398006762	HAMP domain; Region: HAMP; pfam00672
1128398006763	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398006764	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398006765	dimer interface [polypeptide binding]; other site
1128398006766	putative CheW interface [polypeptide binding]; other site
1128398006767	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
1128398006768	Ferritin-like domain; Region: Ferritin; pfam00210
1128398006769	ferroxidase diiron center [ion binding]; other site
1128398006770	NlpC/P60 family; Region: NLPC_P60; cl17555
1128398006771	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
1128398006772	PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase; Region: PAP2_like_2; cd03392
1128398006773	active site
1128398006774	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398006775	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398006776	active site
1128398006777	metal binding site [ion binding]; metal-binding site
1128398006778	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
1128398006779	Ligand Binding Site [chemical binding]; other site
1128398006780	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
1128398006781	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
1128398006782	23S rRNA interface [nucleotide binding]; other site
1128398006783	L3 interface [polypeptide binding]; other site
1128398006784	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
1128398006785	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
1128398006786	dimerization interface 3.5A [polypeptide binding]; other site
1128398006787	active site
1128398006788	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
1128398006789	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637
1128398006790	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1128398006791	Walker A/P-loop; other site
1128398006792	ATP binding site [chemical binding]; other site
1128398006793	Q-loop/lid; other site
1128398006794	ABC transporter signature motif; other site
1128398006795	Walker B; other site
1128398006796	D-loop; other site
1128398006797	H-loop/switch region; other site
1128398006798	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
1128398006799	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
1128398006800	Walker A/P-loop; other site
1128398006801	ATP binding site [chemical binding]; other site
1128398006802	Q-loop/lid; other site
1128398006803	ABC transporter signature motif; other site
1128398006804	Walker B; other site
1128398006805	D-loop; other site
1128398006806	H-loop/switch region; other site
1128398006807	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
1128398006808	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
1128398006809	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
1128398006810	alphaNTD - beta interaction site [polypeptide binding]; other site
1128398006811	alphaNTD homodimer interface [polypeptide binding]; other site
1128398006812	alphaNTD - beta' interaction site [polypeptide binding]; other site
1128398006813	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
1128398006814	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
1128398006815	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
1128398006816	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398006817	RNA binding surface [nucleotide binding]; other site
1128398006818	30S ribosomal protein S11; Validated; Region: PRK05309
1128398006819	Ribosomal protein S13 [Translation, ribosomal structure and biogenesis]; Region: RpsM; COG0099
1128398006820	30S ribosomal protein S13; Region: bact_S13; TIGR03631
1128398006821	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
1128398006822	rRNA binding site [nucleotide binding]; other site
1128398006823	predicted 30S ribosome binding site; other site
1128398006824	KOW motif of Ribosomal Protein L14; Region: KOW_RPL14; cd06088
1128398006825	RNA binding site [nucleotide binding]; other site
1128398006826	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
1128398006827	active site
1128398006828	adenylate kinase; Reviewed; Region: adk; PRK00279
1128398006829	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
1128398006830	AMP-binding site [chemical binding]; other site
1128398006831	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
1128398006832	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
1128398006833	SecY translocase; Region: SecY; pfam00344
1128398006834	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
1128398006835	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
1128398006836	23S rRNA binding site [nucleotide binding]; other site
1128398006837	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
1128398006838	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
1128398006839	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
1128398006840	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
1128398006841	23S rRNA interface [nucleotide binding]; other site
1128398006842	5S rRNA interface [nucleotide binding]; other site
1128398006843	L27 interface [polypeptide binding]; other site
1128398006844	L5 interface [polypeptide binding]; other site
1128398006845	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
1128398006846	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1128398006847	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
1128398006848	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
1128398006849	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
1128398006850	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
1128398006851	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
1128398006852	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
1128398006853	50S ribosomal protein L24; Reviewed; Region: rplX; PRK00004
1128398006854	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
1128398006855	RNA binding site [nucleotide binding]; other site
1128398006856	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
1128398006857	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
1128398006858	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
1128398006859	23S rRNA interface [nucleotide binding]; other site
1128398006860	putative translocon interaction site; other site
1128398006861	signal recognition particle (SRP54) interaction site; other site
1128398006862	L23 interface [polypeptide binding]; other site
1128398006863	trigger factor interaction site; other site
1128398006864	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
1128398006865	23S rRNA interface [nucleotide binding]; other site
1128398006866	5S rRNA interface [nucleotide binding]; other site
1128398006867	putative antibiotic binding site [chemical binding]; other site
1128398006868	L25 interface [polypeptide binding]; other site
1128398006869	L27 interface [polypeptide binding]; other site
1128398006870	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
1128398006871	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
1128398006872	G-X-X-G motif; other site
1128398006873	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
1128398006874	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
1128398006875	putative translocon binding site; other site
1128398006876	protein-rRNA interface [nucleotide binding]; other site
1128398006877	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
1128398006878	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
1128398006879	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
1128398006880	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
1128398006881	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
1128398006882	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
1128398006883	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
1128398006884	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
1128398006885	elongation factor Tu; Reviewed; Region: PRK00049
1128398006886	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1128398006887	G1 box; other site
1128398006888	GEF interaction site [polypeptide binding]; other site
1128398006889	GTP/Mg2+ binding site [chemical binding]; other site
1128398006890	Switch I region; other site
1128398006891	G2 box; other site
1128398006892	G3 box; other site
1128398006893	Switch II region; other site
1128398006894	G4 box; other site
1128398006895	G5 box; other site
1128398006896	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1128398006897	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1128398006898	Antibiotic Binding Site [chemical binding]; other site
1128398006899	elongation factor G; Reviewed; Region: PRK00007
1128398006900	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
1128398006901	G1 box; other site
1128398006902	putative GEF interaction site [polypeptide binding]; other site
1128398006903	GTP/Mg2+ binding site [chemical binding]; other site
1128398006904	Switch I region; other site
1128398006905	G2 box; other site
1128398006906	G3 box; other site
1128398006907	Switch II region; other site
1128398006908	G4 box; other site
1128398006909	G5 box; other site
1128398006910	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
1128398006911	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
1128398006912	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
1128398006913	30S ribosomal protein S7; Validated; Region: PRK05302
1128398006914	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
1128398006915	S17 interaction site [polypeptide binding]; other site
1128398006916	S8 interaction site; other site
1128398006917	16S rRNA interaction site [nucleotide binding]; other site
1128398006918	streptomycin interaction site [chemical binding]; other site
1128398006919	23S rRNA interaction site [nucleotide binding]; other site
1128398006920	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
1128398006921	putative ribosomal protein L7Ae-like; Provisional; Region: PRK13602
1128398006922	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
1128398006923	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
1128398006924	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
1128398006925	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
1128398006926	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
1128398006927	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1128398006928	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
1128398006929	G-loop; other site
1128398006930	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
1128398006931	DNA binding site [nucleotide binding]
1128398006932	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
1128398006933	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
1128398006934	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
1128398006935	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
1128398006936	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
1128398006937	RPB1 interaction site [polypeptide binding]; other site
1128398006938	RPB10 interaction site [polypeptide binding]; other site
1128398006939	RPB11 interaction site [polypeptide binding]; other site
1128398006940	RPB3 interaction site [polypeptide binding]; other site
1128398006941	RPB12 interaction site [polypeptide binding]; other site
1128398006942	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
1128398006943	core dimer interface [polypeptide binding]; other site
1128398006944	peripheral dimer interface [polypeptide binding]; other site
1128398006945	L10 interface [polypeptide binding]; other site
1128398006946	L11 interface [polypeptide binding]; other site
1128398006947	putative EF-Tu interaction site [polypeptide binding]; other site
1128398006948	putative EF-G interaction site [polypeptide binding]; other site
1128398006949	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
1128398006950	23S rRNA interface [nucleotide binding]; other site
1128398006951	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
1128398006952	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
1128398006953	mRNA/rRNA interface [nucleotide binding]; other site
1128398006954	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
1128398006955	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
1128398006956	23S rRNA interface [nucleotide binding]; other site
1128398006957	L7/L12 interface [polypeptide binding]; other site
1128398006958	putative thiostrepton binding site; other site
1128398006959	L25 interface [polypeptide binding]; other site
1128398006960	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
1128398006961	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
1128398006962	putative homodimer interface [polypeptide binding]; other site
1128398006963	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
1128398006964	heterodimer interface [polypeptide binding]; other site
1128398006965	homodimer interface [polypeptide binding]; other site
1128398006966	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
1128398006967	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
1128398006968	elongation factor Tu; Reviewed; Region: PRK00049
1128398006969	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
1128398006970	G1 box; other site
1128398006971	GEF interaction site [polypeptide binding]; other site
1128398006972	GTP/Mg2+ binding site [chemical binding]; other site
1128398006973	Switch I region; other site
1128398006974	G2 box; other site
1128398006975	G3 box; other site
1128398006976	Switch II region; other site
1128398006977	G4 box; other site
1128398006978	G5 box; other site
1128398006979	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
1128398006980	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
1128398006981	Antibiotic Binding Site [chemical binding]; other site
1128398006982	RNA polymerase factor sigma-70; Validated; Region: PRK08295
1128398006983	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398006984	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1128398006985	YacP-like NYN domain; Region: NYN_YacP; cl01491
1128398006986	YacP-like NYN domain; Region: NYN_YacP; pfam05991
1128398006987	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
1128398006988	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
1128398006989	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
1128398006990	FAD-dependent thymidylate synthase; Reviewed; Region: thyX; PRK00847
1128398006991	Ribonuclease III family protein [Replication, recombination, and    repair]; Region: COG1939
1128398006992	active site
1128398006993	metal binding site [ion binding]; metal-binding site
1128398006994	dimerization interface [polypeptide binding]; other site
1128398006995	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1128398006996	tRNA synthetases class I (C) catalytic domain; Region: tRNA-synt_1e; pfam01406
1128398006997	active site
1128398006998	HIGH motif; other site
1128398006999	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
1128398007000	KMSKS motif; other site
1128398007001	tRNA binding surface [nucleotide binding]; other site
1128398007002	anticodon binding site; other site
1128398007003	This DALR domain is found in cysteinyl-tRNA-synthetases; Region: DALR_2; smart00840
1128398007004	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
1128398007005	Serine acetyltransferase, N-terminal; Region: SATase_N; cl05762
1128398007006	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
1128398007007	trimer interface [polypeptide binding]; other site
1128398007008	active site
1128398007009	substrate binding site [chemical binding]; other site
1128398007010	CoA binding site [chemical binding]; other site
1128398007011	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
1128398007012	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1128398007013	active site
1128398007014	HIGH motif; other site
1128398007015	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
1128398007016	active site
1128398007017	KMSKS motif; other site
1128398007018	Predicted secreted protein [Function unknown]; Region: COG4086
1128398007019	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
1128398007020	prolyl-tRNA synthetase; Provisional; Region: PRK09194
1128398007021	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
1128398007022	dimer interface [polypeptide binding]; other site
1128398007023	motif 1; other site
1128398007024	active site
1128398007025	motif 2; other site
1128398007026	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
1128398007027	putative deacylase active site [active]
1128398007028	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
1128398007029	active site
1128398007030	motif 3; other site
1128398007031	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
1128398007032	anticodon binding site; other site
1128398007033	Domain of unknown function (DUF4412); Region: DUF4412; pfam14371
1128398007034	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398007035	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
1128398007036	dimerization interface [polypeptide binding]; other site
1128398007037	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398007038	dimer interface [polypeptide binding]; other site
1128398007039	phosphorylation site [posttranslational modification]
1128398007040	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398007041	ATP binding site [chemical binding]; other site
1128398007042	Mg2+ binding site [ion binding]; other site
1128398007043	G-X-G motif; other site
1128398007044	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398007045	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398007046	active site
1128398007047	phosphorylation site [posttranslational modification]
1128398007048	intermolecular recognition site; other site
1128398007049	dimerization interface [polypeptide binding]; other site
1128398007050	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1128398007051	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
1128398007052	Walker A/P-loop; other site
1128398007053	ATP binding site [chemical binding]; other site
1128398007054	Q-loop/lid; other site
1128398007055	ABC transporter signature motif; other site
1128398007056	Walker B; other site
1128398007057	D-loop; other site
1128398007058	H-loop/switch region; other site
1128398007059	Methyltransferase domain; Region: Methyltransf_31; pfam13847
1128398007060	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398007061	S-adenosylmethionine binding site [chemical binding]; other site
1128398007062	Uncharacterized conserved protein [Function unknown]; Region: COG3603
1128398007063	Family description; Region: ACT_7; pfam13840
1128398007064	Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones]; Region: STE14; COG2020
1128398007065	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398007066	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1128398007067	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
1128398007068	putative FMN binding site [chemical binding]; other site
1128398007069	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
1128398007070	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1128398007071	PhnA protein; Region: PhnA; pfam03831
1128398007072	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398007073	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398007074	Coenzyme A binding pocket [chemical binding]; other site
1128398007075	Protein of unknown function (DUF975); Region: DUF975; cl10504
1128398007076	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
1128398007077	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
1128398007078	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
1128398007079	homotrimer interaction site [polypeptide binding]; other site
1128398007080	zinc binding site [ion binding]; other site
1128398007081	CDP-binding sites; other site
1128398007082	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
1128398007083	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
1128398007084	Probable transposase; Region: OrfB_IS605; pfam01385
1128398007085	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
1128398007086	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
1128398007087	Helix-Turn-Helix DNA binding domain of transcription regulators from the MerR superfamily; Region: HTH_MerR-SF; cl02600
1128398007088	DNA binding residues [nucleotide binding]
1128398007089	Serine Recombinase (SR) family, IS607-like transposase subfamily, catalytic domain; members contain a DNA binding domain with homology to MerR/SoxR located N-terminal to the catalytic domain. Serine recombinases catalyze site-specific recombination of...; Region: SR_IS607_transposase_like; cd03769
1128398007090	catalytic residues [active]
1128398007091	catalytic nucleophile [active]
1128398007092	CrcB-like protein; Region: CRCB; cl09114
1128398007093	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
1128398007094	substrate binding site; other site
1128398007095	dimer interface; other site
1128398007096	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
1128398007097	putative deacylase active site [active]
1128398007098	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
1128398007099	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
1128398007100	putative active site [active]
1128398007101	Transcriptional regulators, similar to M. xanthus CarD [Transcription]; Region: COG1329
1128398007102	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain superfamily; Region: NTP-PPase; cl16941
1128398007103	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
1128398007104	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
1128398007105	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
1128398007106	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cl14786
1128398007107	DNA repair protein RadA; Provisional; Region: PRK11823
1128398007108	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
1128398007109	Walker A motif/ATP binding site; other site
1128398007110	ATP binding site [chemical binding]; other site
1128398007111	Walker B motif; other site
1128398007112	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
1128398007113	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
1128398007114	Clp amino terminal domain; Region: Clp_N; pfam02861
1128398007115	Clp amino terminal domain; Region: Clp_N; pfam02861
1128398007116	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398007117	Walker A motif; other site
1128398007118	ATP binding site [chemical binding]; other site
1128398007119	Walker B motif; other site
1128398007120	arginine finger; other site
1128398007121	UvrB/uvrC motif; Region: UVR; pfam02151
1128398007122	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398007123	Walker A motif; other site
1128398007124	ATP binding site [chemical binding]; other site
1128398007125	Walker B motif; other site
1128398007126	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
1128398007127	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
1128398007128	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
1128398007129	ADP binding site [chemical binding]; other site
1128398007130	phosphagen binding site; other site
1128398007131	substrate specificity loop; other site
1128398007132	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
1128398007133	UvrB/uvrC motif; Region: UVR; pfam02151
1128398007134	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; cl01850
1128398007135	aspartate aminotransferase; Provisional; Region: PRK06836
1128398007136	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398007137	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398007138	homodimer interface [polypeptide binding]; other site
1128398007139	catalytic residue [active]
1128398007140	Tubby C 2; Region: Tub_2; cl02043
1128398007141	Flavin Reductases; Region: FlaRed; cl00801
1128398007142	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
1128398007143	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1128398007144	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1128398007145	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
1128398007146	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1128398007147	ATP-grasp domain; Region: ATP-grasp_4; cl17255
1128398007148	MGS-like domain. This domain composes the whole protein of methylglyoxal synthetase, which catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The family also includes the C-terminal domain in carbamoyl phosphate...; Region: MGS-like; cl00245
1128398007149	substrate binding site [chemical binding]; other site
1128398007150	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
1128398007151	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
1128398007152	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
1128398007153	catalytic site [active]
1128398007154	subunit interface [polypeptide binding]; other site
1128398007155	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
1128398007156	NADH:flavin oxidoreductases, Old Yellow Enzyme family [Energy production and conversion]; Region: NemA; COG1902
1128398007157	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
1128398007158	active site
1128398007159	FMN binding site [chemical binding]; other site
1128398007160	substrate binding site [chemical binding]; other site
1128398007161	putative catalytic residue [active]
1128398007162	Predicted transcriptional regulators [Transcription]; Region: COG1733
1128398007163	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
1128398007164	helicase 45; Provisional; Region: PTZ00424
1128398007165	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1128398007166	ATP binding site [chemical binding]; other site
1128398007167	Mg++ binding site [ion binding]; other site
1128398007168	motif III; other site
1128398007169	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398007170	nucleotide binding region [chemical binding]; other site
1128398007171	ATP-binding site [chemical binding]; other site
1128398007172	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398007173	dimerization interface [polypeptide binding]; other site
1128398007174	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398007175	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398007176	dimer interface [polypeptide binding]; other site
1128398007177	phosphorylation site [posttranslational modification]
1128398007178	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398007179	ATP binding site [chemical binding]; other site
1128398007180	Mg2+ binding site [ion binding]; other site
1128398007181	G-X-G motif; other site
1128398007182	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398007183	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398007184	active site
1128398007185	phosphorylation site [posttranslational modification]
1128398007186	intermolecular recognition site; other site
1128398007187	dimerization interface [polypeptide binding]; other site
1128398007188	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398007189	DNA binding site [nucleotide binding]
1128398007190	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
1128398007191	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
1128398007192	Clp amino terminal domain; Region: Clp_N; pfam02861
1128398007193	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398007194	Walker A motif; other site
1128398007195	ATP binding site [chemical binding]; other site
1128398007196	Walker B motif; other site
1128398007197	arginine finger; other site
1128398007198	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398007199	Walker A motif; other site
1128398007200	ATP binding site [chemical binding]; other site
1128398007201	Walker B motif; other site
1128398007202	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
1128398007203	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398007204	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398007205	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1128398007206	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
1128398007207	conserved cys residue [active]
1128398007208	Predicted transcriptional regulators [Transcription]; Region: COG1695
1128398007209	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
1128398007210	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1128398007211	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
1128398007212	NAD(P) binding site [chemical binding]; other site
1128398007213	active site
1128398007214	Isoprenoid Biosynthesis enzymes, Class 1; Region: Isoprenoid_Biosyn_C1; cl00210
1128398007215	aspartate-rich region 2; other site
1128398007216	substrate-Mg2+ binding site; other site
1128398007217	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08665
1128398007218	Ribonucleotide reductase, all-alpha domain; Region: Ribonuc_red_lgN; pfam00317
1128398007219	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
1128398007220	active site
1128398007221	dimer interface [polypeptide binding]; other site
1128398007222	effector binding site; other site
1128398007223	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
1128398007224	TSCPD domain; Region: TSCPD; pfam12637
1128398007225	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
1128398007226	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1128398007227	catalytic residues [active]
1128398007228	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1128398007229	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
1128398007230	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
1128398007231	amino acid carrier protein; Region: agcS; TIGR00835
1128398007232	YtxH-like protein; Region: YtxH; pfam12732
1128398007233	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
1128398007234	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
1128398007235	dimer interface [polypeptide binding]; other site
1128398007236	putative anticodon binding site; other site
1128398007237	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
1128398007238	motif 1; other site
1128398007239	active site
1128398007240	motif 2; other site
1128398007241	motif 3; other site
1128398007242	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
1128398007243	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
1128398007244	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
1128398007245	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
1128398007246	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
1128398007247	FMN binding site [chemical binding]; other site
1128398007248	active site
1128398007249	catalytic residues [active]
1128398007250	substrate binding site [chemical binding]; other site
1128398007251	pantothenate kinase; Reviewed; Region: PRK13318
1128398007252	Predicted membrane protein [Function unknown]; Region: COG4684
1128398007253	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1128398007254	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
1128398007255	Predicted membrane protein [Function unknown]; Region: COG4684
1128398007256	Biotin operon repressor [Transcription]; Region: BirA; COG1654
1128398007257	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
1128398007258	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; cl14057
1128398007259	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
1128398007260	FtsH Extracellular; Region: FtsH_ext; pfam06480
1128398007261	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
1128398007262	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
1128398007263	Walker A motif; other site
1128398007264	ATP binding site [chemical binding]; other site
1128398007265	Walker B motif; other site
1128398007266	arginine finger; other site
1128398007267	Peptidase family M41; Region: Peptidase_M41; pfam01434
1128398007268	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398007269	active site
1128398007270	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1128398007271	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
1128398007272	Ligand Binding Site [chemical binding]; other site
1128398007273	TilS substrate C-terminal domain; Region: TilS_C; smart00977
1128398007274	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
1128398007275	active site
1128398007276	ATP binding site [chemical binding]; other site
1128398007277	substrate binding site [chemical binding]; other site
1128398007278	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
1128398007279	metal ion-dependent adhesion site (MIDAS); other site
1128398007280	stage II sporulation protein E; Region: spore_II_E; TIGR02865
1128398007281	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1128398007282	hypothetical protein; Provisional; Region: PRK05807
1128398007283	S1_RPS1_repeat_hs4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_hs4; cd05692
1128398007284	RNA binding site [nucleotide binding]; other site
1128398007285	Septum formation initiator; Region: DivIC; pfam04977
1128398007286	Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; pfam09578
1128398007287	YabP family; Region: YabP; cl06766
1128398007288	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398007289	RNA binding surface [nucleotide binding]; other site
1128398007290	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
1128398007291	IHF dimer interface [polypeptide binding]; other site
1128398007292	IHF - DNA interface [nucleotide binding]; other site
1128398007293	Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956
1128398007294	N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723
1128398007295	putative SAM binding site [chemical binding]; other site
1128398007296	putative homodimer interface [polypeptide binding]; other site
1128398007297	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
1128398007298	homodimer interface [polypeptide binding]; other site
1128398007299	metal binding site [ion binding]; metal-binding site
1128398007300	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
1128398007301	homodimer interface [polypeptide binding]; other site
1128398007302	active site
1128398007303	putative chemical substrate binding site [chemical binding]; other site
1128398007304	metal binding site [ion binding]; metal-binding site
1128398007305	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
1128398007306	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
1128398007307	stage V sporulation protein T; Region: spore_V_T; TIGR02851
1128398007308	Antidote-toxin recognition MazE; Region: Antitoxin-MazE; pfam04014
1128398007309	SurA N-terminal domain; Region: SurA_N_3; cl07813
1128398007310	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
1128398007311	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
1128398007312	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
1128398007313	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1128398007314	ATP binding site [chemical binding]; other site
1128398007315	putative Mg++ binding site [ion binding]; other site
1128398007316	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398007317	nucleotide binding region [chemical binding]; other site
1128398007318	ATP-binding site [chemical binding]; other site
1128398007319	TRCF domain; Region: TRCF; pfam03461
1128398007320	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
1128398007321	putative active site [active]
1128398007322	catalytic residue [active]
1128398007323	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
1128398007324	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
1128398007325	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398007326	active site
1128398007327	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
1128398007328	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
1128398007329	Substrate binding site; other site
1128398007330	Mg++ binding site; other site
1128398007331	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
1128398007332	active site
1128398007333	substrate binding site [chemical binding]; other site
1128398007334	CoA binding site [chemical binding]; other site
1128398007335	regulatory protein SpoVG; Reviewed; Region: PRK13259
1128398007336	pur operon repressor; Provisional; Region: PRK09213
1128398007337	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
1128398007338	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
1128398007339	active site
1128398007340	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
1128398007341	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
1128398007342	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
1128398007343	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
1128398007344	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
1128398007345	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
1128398007346	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
1128398007347	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398007348	catalytic loop [active]
1128398007349	iron binding site [ion binding]; other site
1128398007350	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
1128398007351	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
1128398007352	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
1128398007353	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
1128398007354	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1128398007355	Transcriptional regulator [Transcription]; Region: LytR; COG1316
1128398007356	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
1128398007357	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
1128398007358	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
1128398007359	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
1128398007360	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
1128398007361	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
1128398007362	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
1128398007363	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
1128398007364	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
1128398007365	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
1128398007366	carboxyltransferase (CT) interaction site; other site
1128398007367	biotinylation site [posttranslational modification]; other site
1128398007368	4Fe-4S binding domain; Region: Fer4; cl02805
1128398007369	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1128398007370	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
1128398007371	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
1128398007372	putative active site [active]
1128398007373	putative metal binding site [ion binding]; other site
1128398007374	PAS fold; Region: PAS_4; pfam08448
1128398007375	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
1128398007376	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
1128398007377	hybrid cluster protein; Provisional; Region: PRK05290
1128398007378	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398007379	ACS interaction site; other site
1128398007380	CODH interaction site; other site
1128398007381	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
1128398007382	hybrid metal cluster; other site
1128398007383	Superoxide reductase-like (SORL) domain, class II; SORL-domains are present in a family of mononuclear non-heme iron proteins that includes superoxide reductase and desulfoferrodoxin.  Superoxide reductase-like proteins scavenge superoxide anion radicals...; Region: SORL_classII; cd03172
1128398007384	non-heme iron binding site [ion binding]; other site
1128398007385	tetramer interface [polypeptide binding]; other site
1128398007386	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
1128398007387	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
1128398007388	active site
1128398007389	HIGH motif; other site
1128398007390	dimer interface [polypeptide binding]; other site
1128398007391	KMSKS motif; other site
1128398007392	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
1128398007393	RNA binding surface [nucleotide binding]; other site
1128398007394	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
1128398007395	MarR family; Region: MarR; pfam01047
1128398007396	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
1128398007397	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
1128398007398	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
1128398007399	putative active site [active]
1128398007400	putative CoA binding site [chemical binding]; other site
1128398007401	nudix motif; other site
1128398007402	metal binding site [ion binding]; metal-binding site
1128398007403	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1128398007404	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
1128398007405	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
1128398007406	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
1128398007407	pyrroline-5-carboxylate reductase; Region: PLN02688
1128398007408	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
1128398007409	active site
1128398007410	metal binding site [ion binding]; metal-binding site
1128398007411	homotetramer interface [polypeptide binding]; other site
1128398007412	Protein of unknown function (DUF4011); Region: DUF4011; pfam13195
1128398007413	AAA domain; Region: AAA_11; pfam13086
1128398007414	Part of AAA domain; Region: AAA_19; pfam13245
1128398007415	Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair]; Region: COG1112
1128398007416	AAA domain; Region: AAA_12; pfam13087
1128398007417	Superfamily of nucleases including Short Patch Repair (Vsr) Endonucleases, archaeal Holliday junction resolvases, MutH methy-directed DNA mismatch-repair endonucleases, and catalytic domains of many restriction endonucleases, such as EcoRI, BamHI, and...; Region: Restriction_endonuclease_like; cl00277
1128398007418	putative active site [active]
1128398007419	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivF; COG0410
1128398007420	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
1128398007421	Walker A/P-loop; other site
1128398007422	ATP binding site [chemical binding]; other site
1128398007423	Q-loop/lid; other site
1128398007424	ABC transporter signature motif; other site
1128398007425	Walker B; other site
1128398007426	D-loop; other site
1128398007427	H-loop/switch region; other site
1128398007428	ABC-type branched-chain amino acid transport systems, ATPase component [Amino acid transport and metabolism]; Region: LivG; COG0411
1128398007429	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
1128398007430	Walker A/P-loop; other site
1128398007431	ATP binding site [chemical binding]; other site
1128398007432	Q-loop/lid; other site
1128398007433	ABC transporter signature motif; other site
1128398007434	Walker B; other site
1128398007435	D-loop; other site
1128398007436	H-loop/switch region; other site
1128398007437	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
1128398007438	TM-ABC transporter signature motif; other site
1128398007439	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
1128398007440	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
1128398007441	TM-ABC transporter signature motif; other site
1128398007442	ABC-type branched-chain amino acid transport systems, periplasmic component [Amino acid transport and metabolism]; Region: LivK; COG0683
1128398007443	Type I periplasmic ligand-binding domain of uncharacterized ABC (Atpase Binding Cassette)-type active transport systems that are predicted to be involved in uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_ligand_binding_like_12; cd06347
1128398007444	putative ligand binding site [chemical binding]; other site
1128398007445	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
1128398007446	Nucleoside recognition; Region: Gate; pfam07670
1128398007447	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
1128398007448	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398007449	catalytic residue [active]
1128398007450	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1128398007451	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398007452	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398007453	ABC transporter; Region: ABC_tran_2; pfam12848
1128398007454	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398007455	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
1128398007456	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
1128398007457	PAS fold; Region: PAS_3; pfam08447
1128398007458	putative active site [active]
1128398007459	heme pocket [chemical binding]; other site
1128398007460	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398007461	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398007462	metal binding site [ion binding]; metal-binding site
1128398007463	active site
1128398007464	I-site; other site
1128398007465	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1128398007466	threonine dehydratase; Provisional; Region: PRK08198
1128398007467	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
1128398007468	tetramer interface [polypeptide binding]; other site
1128398007469	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398007470	catalytic residue [active]
1128398007471	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
1128398007472	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
1128398007473	GIY-YIG motif/motif A; other site
1128398007474	putative active site [active]
1128398007475	putative metal binding site [ion binding]; other site
1128398007476	FMN-binding domain; Region: FMN_bind; cl01081
1128398007477	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
1128398007478	S1 domain; Region: S1_2; pfam13509
1128398007479	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
1128398007480	RNA binding site [nucleotide binding]; other site
1128398007481	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
1128398007482	large-conductance mechanosensitive channel; Provisional; Region: mscL; PRK13952
1128398007483	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
1128398007484	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1128398007485	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
1128398007486	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
1128398007487	dimer interface [polypeptide binding]; other site
1128398007488	decamer (pentamer of dimers) interface [polypeptide binding]; other site
1128398007489	catalytic triad [active]
1128398007490	peroxidatic and resolving cysteines [active]
1128398007491	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
1128398007492	active site clefts [active]
1128398007493	zinc binding site [ion binding]; other site
1128398007494	dimer interface [polypeptide binding]; other site
1128398007495	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cd00350
1128398007496	Rubredoxin; Region: Rubredoxin; pfam00301
1128398007497	iron binding site [ion binding]; other site
1128398007498	Rubrerythrin [Energy production and conversion]; Region: COG1592
1128398007499	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
1128398007500	diiron binding motif [ion binding]; other site
1128398007501	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
1128398007502	metal binding site 2 [ion binding]; metal-binding site
1128398007503	putative DNA binding helix; other site
1128398007504	metal binding site 1 [ion binding]; metal-binding site
1128398007505	dimer interface [polypeptide binding]; other site
1128398007506	structural Zn2+ binding site [ion binding]; other site
1128398007507	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398007508	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398007509	dimerization interface [polypeptide binding]; other site
1128398007510	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398007511	dimer interface [polypeptide binding]; other site
1128398007512	putative CheW interface [polypeptide binding]; other site
1128398007513	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398007514	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398007515	Zn2+ binding site [ion binding]; other site
1128398007516	Mg2+ binding site [ion binding]; other site
1128398007517	Cache domain; Region: Cache_1; pfam02743
1128398007518	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398007519	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398007520	dimer interface [polypeptide binding]; other site
1128398007521	putative CheW interface [polypeptide binding]; other site
1128398007522	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
1128398007523	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
1128398007524	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
1128398007525	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007526	dimer interface [polypeptide binding]; other site
1128398007527	conserved gate region; other site
1128398007528	putative PBP binding loops; other site
1128398007529	ABC-ATPase subunit interface; other site
1128398007530	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007531	dimer interface [polypeptide binding]; other site
1128398007532	conserved gate region; other site
1128398007533	putative PBP binding loops; other site
1128398007534	ABC-ATPase subunit interface; other site
1128398007535	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
1128398007536	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398007537	substrate binding pocket [chemical binding]; other site
1128398007538	membrane-bound complex binding site; other site
1128398007539	hinge residues; other site
1128398007540	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1128398007541	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1128398007542	Walker A/P-loop; other site
1128398007543	ATP binding site [chemical binding]; other site
1128398007544	Q-loop/lid; other site
1128398007545	ABC transporter signature motif; other site
1128398007546	Walker B; other site
1128398007547	D-loop; other site
1128398007548	H-loop/switch region; other site
1128398007549	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1128398007550	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007551	dimer interface [polypeptide binding]; other site
1128398007552	conserved gate region; other site
1128398007553	ABC-ATPase subunit interface; other site
1128398007554	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1128398007555	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007556	dimer interface [polypeptide binding]; other site
1128398007557	conserved gate region; other site
1128398007558	putative PBP binding loops; other site
1128398007559	ABC-ATPase subunit interface; other site
1128398007560	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1128398007561	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007562	dimer interface [polypeptide binding]; other site
1128398007563	conserved gate region; other site
1128398007564	putative PBP binding loops; other site
1128398007565	ABC-ATPase subunit interface; other site
1128398007566	phosphonate ABC transporter, permease protein PhnE; Region: PhnE; TIGR01097
1128398007567	phosphonate ABC transporter, ATP-binding protein; Region: ABC_phnC; TIGR02315
1128398007568	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
1128398007569	Walker A/P-loop; other site
1128398007570	ATP binding site [chemical binding]; other site
1128398007571	Q-loop/lid; other site
1128398007572	ABC transporter signature motif; other site
1128398007573	Walker B; other site
1128398007574	D-loop; other site
1128398007575	H-loop/switch region; other site
1128398007576	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; pfam12974
1128398007577	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398007578	substrate binding pocket [chemical binding]; other site
1128398007579	membrane-bound complex binding site; other site
1128398007580	hinge residues; other site
1128398007581	Predicted membrane protein [Function unknown]; Region: COG3212
1128398007582	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
1128398007583	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1128398007584	tRNA 2-selenouridine synthase; Region: tRNA_sel_U_synt; TIGR03167
1128398007585	active site residue [active]
1128398007586	Protein of unknown function (DUF523); Region: DUF523; cl00733
1128398007587	FOG: CBS domain [General function prediction only]; Region: COG0517
1128398007588	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the BON (bacterial OsmY and nodulation domain) domain. BON is a putative phospholipid-binding domain found in a family of osmotic shock protection...; Region: CBS_pair_BON_assoc; cd04586
1128398007589	Uncharacterized FAD-dependent dehydrogenases [General function prediction only]; Region: COG2509
1128398007590	Uncharacterized conserved protein [Function unknown]; Region: COG1434
1128398007591	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
1128398007592	putative active site [active]
1128398007593	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
1128398007594	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398007595	S-adenosylmethionine binding site [chemical binding]; other site
1128398007596	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
1128398007597	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
1128398007598	G1 box; other site
1128398007599	GTP/Mg2+ binding site [chemical binding]; other site
1128398007600	Switch I region; other site
1128398007601	G2 box; other site
1128398007602	G3 box; other site
1128398007603	Switch II region; other site
1128398007604	G4 box; other site
1128398007605	G5 box; other site
1128398007606	Nucleoside recognition; Region: Gate; pfam07670
1128398007607	Nucleoside recognition; Region: Gate; pfam07670
1128398007608	This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; Region: FeoA; smart00899
1128398007609	Protein of unknown function (DUF2759); Region: DUF2759; pfam10958
1128398007610	3-oxoacyl-[acyl-carrier-protein]; Region: FabH; COG0332
1128398007611	Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the...; Region: cond_enzymes; cl09938
1128398007612	active site
1128398007613	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
1128398007614	Periplasmic binding protein YvrC.  These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct...; Region: YvrC; cd01143
1128398007615	putative binding site residues; other site
1128398007616	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398007617	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398007618	ABC-ATPase subunit  interface; other site
1128398007619	dimer interface [polypeptide binding]; other site
1128398007620	putative PBP binding regions; other site
1128398007621	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398007622	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398007623	Walker A/P-loop; other site
1128398007624	ATP binding site [chemical binding]; other site
1128398007625	Q-loop/lid; other site
1128398007626	ABC transporter signature motif; other site
1128398007627	Walker B; other site
1128398007628	D-loop; other site
1128398007629	H-loop/switch region; other site
1128398007630	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
1128398007631	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1128398007632	inhibitor-cofactor binding pocket; inhibition site
1128398007633	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398007634	catalytic residue [active]
1128398007635	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
1128398007636	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
1128398007637	dimer interface [polypeptide binding]; other site
1128398007638	active site
1128398007639	Schiff base residues; other site
1128398007640	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
1128398007641	active site
1128398007642	SAM binding site [chemical binding]; other site
1128398007643	homodimer interface [polypeptide binding]; other site
1128398007644	Uroporphyrinogen-III synthase [Coenzyme metabolism]; Region: HemD; COG1587
1128398007645	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
1128398007646	active site
1128398007647	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
1128398007648	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cl17708
1128398007649	domain interfaces; other site
1128398007650	active site
1128398007651	precorrin-2 dehydrogenase; Provisional; Region: PRK05562
1128398007652	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
1128398007653	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
1128398007654	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
1128398007655	tRNA; other site
1128398007656	putative tRNA binding site [nucleotide binding]; other site
1128398007657	putative NADP binding site [chemical binding]; other site
1128398007658	Glutamyl-tRNAGlu reductase, dimerisation domain; Region: GlutR_dimer; pfam00745
1128398007659	Precorrin-6x reductase [Coenzyme metabolism]; Region: CobK; COG2099
1128398007660	cobalt-precorrin-6x reductase; Reviewed; Region: PRK08057
1128398007661	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
1128398007662	diphthine synthase; Region: dph5; TIGR00522
1128398007663	active site
1128398007664	SAM binding site [chemical binding]; other site
1128398007665	homodimer interface [polypeptide binding]; other site
1128398007666	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
1128398007667	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
1128398007668	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
1128398007669	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
1128398007670	Diphthamide biosynthesis methyltransferase [Translation, ribosomal structure and biogenesis]; Region: DPH5; COG1798
1128398007671	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
1128398007672	active site
1128398007673	SAM binding site [chemical binding]; other site
1128398007674	homodimer interface [polypeptide binding]; other site
1128398007675	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
1128398007676	active site
1128398007677	SAM binding site [chemical binding]; other site
1128398007678	homodimer interface [polypeptide binding]; other site
1128398007679	Precorrin-6B methylase 2 [Coenzyme metabolism]; Region: CobL; COG2242
1128398007680	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398007681	S-adenosylmethionine binding site [chemical binding]; other site
1128398007682	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
1128398007683	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398007684	Coenzyme A binding pocket [chemical binding]; other site
1128398007685	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398007686	DNA binding site [nucleotide binding]
1128398007687	integron integrase; Region: integrase_gron; TIGR02249
1128398007688	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
1128398007689	active site
1128398007690	DNA binding site [nucleotide binding]
1128398007691	Int/Topo IB signature motif; other site
1128398007692	Domain of unknown function (DUF4179); Region: DUF4179; pfam13786
1128398007693	RNA polymerase factor sigma-70; Validated; Region: PRK06811
1128398007694	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398007695	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1128398007696	DNA binding residues [nucleotide binding]
1128398007697	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
1128398007698	active site
1128398007699	putative homodimer interface [polypeptide binding]; other site
1128398007700	SAM binding site [chemical binding]; other site
1128398007701	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
1128398007702	precorrin-8X methylmutase; Validated; Region: cbiC; PRK05575
1128398007703	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; cl00913
1128398007704	Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism]; Region: COG2138
1128398007705	Sirohydrochlorin cobalt chelatase (CbiX) and sirohydrochlorin iron chelatase (SirB), N-terminal domain. SirB catalyzes the ferro-chelation of sirohydrochlorin to siroheme, the prosthetic group of sulfite and nitrite reductases. CbiX is a cobaltochelatase; Region: CbiX_SirB_N; cd03416
1128398007706	putative active site [active]
1128398007707	cobalt ABC transporter, permease protein CbiQ; Region: CbiQ_TIGR; TIGR02454
1128398007708	cobalt transport protein CbiN; Provisional; Region: PRK02898
1128398007709	cobalt transport protein CbiM; Validated; Region: PRK08319
1128398007710	Cobalt uptake substrate-specific transmembrane region; Region: CbiM; pfam01891
1128398007711	Predicted membrane protein (DUF2238); Region: DUF2238; cl01464
1128398007712	HAMP domain; Region: HAMP; pfam00672
1128398007713	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398007714	dimer interface [polypeptide binding]; other site
1128398007715	phosphorylation site [posttranslational modification]
1128398007716	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
1128398007717	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398007718	ATP binding site [chemical binding]; other site
1128398007719	G-X-G motif; other site
1128398007720	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398007721	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398007722	active site
1128398007723	phosphorylation site [posttranslational modification]
1128398007724	intermolecular recognition site; other site
1128398007725	dimerization interface [polypeptide binding]; other site
1128398007726	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398007727	DNA binding site [nucleotide binding]
1128398007728	CotH protein; Region: CotH; pfam08757
1128398007729	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
1128398007730	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
1128398007731	putative metal binding residues [ion binding]; other site
1128398007732	signature motif; other site
1128398007733	dimer interface [polypeptide binding]; other site
1128398007734	active site
1128398007735	polyP binding site; other site
1128398007736	substrate binding site [chemical binding]; other site
1128398007737	acceptor-phosphate pocket; other site
1128398007738	Aldehyde:ferredoxin oxidoreductase [Energy production and conversion]; Region: COG2414
1128398007739	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
1128398007740	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
1128398007741	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
1128398007742	MoaE interaction surface [polypeptide binding]; other site
1128398007743	MoeB interaction surface [polypeptide binding]; other site
1128398007744	thiocarboxylated glycine; other site
1128398007745	hypothetical protein; Provisional; Region: PRK08328
1128398007746	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
1128398007747	ATP binding site [chemical binding]; other site
1128398007748	substrate interface [chemical binding]; other site
1128398007749	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1128398007750	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398007751	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398007752	dimer interface [polypeptide binding]; other site
1128398007753	putative CheW interface [polypeptide binding]; other site
1128398007754	Predicted membrane protein [Function unknown]; Region: COG4267
1128398007755	This family is most closely related to the GT1 family of glycosyltransferases. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can...; Region: GT1_like_3; cd03813
1128398007756	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
1128398007757	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
1128398007758	GAF domain; Region: GAF_3; pfam13492
1128398007759	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
1128398007760	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
1128398007761	putative metal binding residues [ion binding]; other site
1128398007762	signature motif; other site
1128398007763	dimer interface [polypeptide binding]; other site
1128398007764	active site
1128398007765	polyP binding site; other site
1128398007766	substrate binding site [chemical binding]; other site
1128398007767	acceptor-phosphate pocket; other site
1128398007768	CotH protein; Region: CotH; pfam08757
1128398007769	TM1410 hypothetical-related protein; Region: DUF297; pfam03537
1128398007770	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
1128398007771	UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane]; Region: GalE; COG1087
1128398007772	NAD(P) binding site [chemical binding]; other site
1128398007773	active site
1128398007774	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
1128398007775	Predicted transcriptional regulators [Transcription]; Region: COG1695
1128398007776	Transcriptional regulator PadR-like family; Region: PadR; cl17335
1128398007777	GTPases - Sulfate adenylate transferase subunit 1 [Inorganic ion transport and metabolism]; Region: CysN; COG2895
1128398007778	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
1128398007779	CysD dimerization site [polypeptide binding]; other site
1128398007780	G1 box; other site
1128398007781	putative GEF interaction site [polypeptide binding]; other site
1128398007782	GTP/Mg2+ binding site [chemical binding]; other site
1128398007783	Switch I region; other site
1128398007784	G2 box; other site
1128398007785	G3 box; other site
1128398007786	Switch II region; other site
1128398007787	G4 box; other site
1128398007788	G5 box; other site
1128398007789	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
1128398007790	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
1128398007791	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
1128398007792	active site
1128398007793	sulfate adenylyltransferase, small subunit; Region: CysD; TIGR02039
1128398007794	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
1128398007795	Active Sites [active]
1128398007796	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
1128398007797	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007798	dimer interface [polypeptide binding]; other site
1128398007799	conserved gate region; other site
1128398007800	putative PBP binding loops; other site
1128398007801	ABC-ATPase subunit interface; other site
1128398007802	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
1128398007803	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
1128398007804	Walker A/P-loop; other site
1128398007805	ATP binding site [chemical binding]; other site
1128398007806	Q-loop/lid; other site
1128398007807	ABC transporter signature motif; other site
1128398007808	Walker B; other site
1128398007809	D-loop; other site
1128398007810	H-loop/switch region; other site
1128398007811	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
1128398007812	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398007813	substrate binding pocket [chemical binding]; other site
1128398007814	membrane-bound complex binding site; other site
1128398007815	hinge residues; other site
1128398007816	Ferredoxin [Energy production and conversion]; Region: COG1146
1128398007817	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
1128398007818	adenylylsulfate reductase subunit alpha; Validated; Region: PRK06854
1128398007819	L-aspartate oxidase; Provisional; Region: PRK06175
1128398007820	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
1128398007821	shikimate kinase; Reviewed; Region: aroK; PRK00131
1128398007822	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
1128398007823	ligand-binding site [chemical binding]; other site
1128398007824	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
1128398007825	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1128398007826	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
1128398007827	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
1128398007828	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398007829	Coenzyme A binding pocket [chemical binding]; other site
1128398007830	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398007831	dimer interface [polypeptide binding]; other site
1128398007832	putative CheW interface [polypeptide binding]; other site
1128398007833	metallo-beta-lactamase/flavodoxin domain-containing protein; Provisional; Region: PRK11921
1128398007834	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398007835	Flavodoxin-like fold; Region: Flavodoxin_2; cl00438
1128398007836	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1128398007837	Homocysteine S-methyltransferase; Region: S-methyl_trans; pfam02574
1128398007838	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
1128398007839	substrate binding pocket [chemical binding]; other site
1128398007840	dimer interface [polypeptide binding]; other site
1128398007841	inhibitor binding site; inhibition site
1128398007842	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
1128398007843	methyltransferase cognate corrinoid proteins, Methanosarcina family; Region: pyl_corrinoid; TIGR02370
1128398007844	B12 binding site [chemical binding]; other site
1128398007845	cobalt ligand [ion binding]; other site
1128398007846	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
1128398007847	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
1128398007848	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398007849	active site
1128398007850	phosphorylation site [posttranslational modification]
1128398007851	intermolecular recognition site; other site
1128398007852	dimerization interface [polypeptide binding]; other site
1128398007853	CheB methylesterase; Region: CheB_methylest; pfam01339
1128398007854	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
1128398007855	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
1128398007856	Nitrogen regulatory protein P-II; Region: P-II; smart00938
1128398007857	Protein of unknown function (DUF1538); Region: DUF1538; pfam07556
1128398007858	Uncharacterized conserved protein [Function unknown]; Region: COG4938
1128398007859	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398007860	Walker A/P-loop; other site
1128398007861	ATP binding site [chemical binding]; other site
1128398007862	Protein of unknown function (DUF3696); Region: DUF3696; pfam12476
1128398007863	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
1128398007864	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
1128398007865	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
1128398007866	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
1128398007867	flavodoxin; Provisional; Region: PRK05568
1128398007868	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
1128398007869	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398007870	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398007871	active site
1128398007872	metal binding site [ion binding]; metal-binding site
1128398007873	Sporulation related domain; Region: SPOR; pfam05036
1128398007874	bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; Reviewed; Region: PRK08645
1128398007875	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; cl14105
1128398007876	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
1128398007877	FAD binding site [chemical binding]; other site
1128398007878	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
1128398007879	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
1128398007880	active site
1128398007881	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
1128398007882	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
1128398007883	Walker A/P-loop; other site
1128398007884	ATP binding site [chemical binding]; other site
1128398007885	Q-loop/lid; other site
1128398007886	ABC transporter signature motif; other site
1128398007887	Walker B; other site
1128398007888	D-loop; other site
1128398007889	H-loop/switch region; other site
1128398007890	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
1128398007891	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
1128398007892	ABC-ATPase subunit  interface; other site
1128398007893	dimer interface [polypeptide binding]; other site
1128398007894	putative PBP binding regions; other site
1128398007895	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
1128398007896	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
1128398007897	intersubunit interface [polypeptide binding]; other site
1128398007898	NTPase; Region: NTPase_1; cl17478
1128398007899	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
1128398007900	Ligand Binding Site [chemical binding]; other site
1128398007901	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
1128398007902	adenosylmethionine-8-amino-7-oxononanoate transaminase; Region: bioA; TIGR00508
1128398007903	inhibitor-cofactor binding pocket; inhibition site
1128398007904	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398007905	catalytic residue [active]
1128398007906	AAA domain; Region: AAA_26; pfam13500
1128398007907	dithiobiotin synthetase; Reviewed; Region: bioD; PRK00090
1128398007908	pyridoxal phosphate-dependent acyltransferase, putative; Region: gly_Cac_T_rel; TIGR01825
1128398007909	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
1128398007910	substrate-cofactor binding pocket; other site
1128398007911	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398007912	catalytic residue [active]
1128398007913	6-carboxyhexanoate--CoA ligase; Region: BioW; cl00625
1128398007914	AAA domain; Region: AAA_32; pfam13654
1128398007915	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
1128398007916	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
1128398007917	PilZ domain; Region: PilZ; pfam07238
1128398007918	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398007919	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398007920	Zn2+ binding site [ion binding]; other site
1128398007921	Mg2+ binding site [ion binding]; other site
1128398007922	Late competence development protein ComFB; Region: ComFB; pfam10719
1128398007923	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1128398007924	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
1128398007925	CPxP  motif; other site
1128398007926	putative selenium metabolism protein, YedE family; Region: seleno_YedE; TIGR04112
1128398007927	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
1128398007928	benzoyl-CoA reductase, subunit C; Region: benz_CoA_red_C; TIGR02263
1128398007929	benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260
1128398007930	Protein of unknown function (DUF1847); Region: DUF1847; pfam08901
1128398007931	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
1128398007932	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
1128398007933	Walker A/P-loop; other site
1128398007934	ATP binding site [chemical binding]; other site
1128398007935	Q-loop/lid; other site
1128398007936	ABC transporter signature motif; other site
1128398007937	Walker B; other site
1128398007938	D-loop; other site
1128398007939	H-loop/switch region; other site
1128398007940	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
1128398007941	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398007942	dimer interface [polypeptide binding]; other site
1128398007943	conserved gate region; other site
1128398007944	putative PBP binding loops; other site
1128398007945	ABC-ATPase subunit interface; other site
1128398007946	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
1128398007947	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
1128398007948	substrate binding pocket [chemical binding]; other site
1128398007949	membrane-bound complex binding site; other site
1128398007950	hinge residues; other site
1128398007951	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1128398007952	Predicted inhibitor of MCP methylation, homolog of CheC [Cell motility and secretion]; Region: COG1406
1128398007953	Chemotaxis phosphatase CheX; Region: CheX; pfam13690
1128398007954	Hemerythrin; Region: Hemerythrin; cd12107
1128398007955	Fe binding site [ion binding]; other site
1128398007956	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398007957	Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins; Region: CE4_Ecf1_like_5s; cd10969
1128398007958	putative active site [active]
1128398007959	putative metal binding site [ion binding]; other site
1128398007960	Acyltransferase family; Region: Acyl_transf_3; pfam01757
1128398007961	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
1128398007962	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398007963	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398007964	active site
1128398007965	phosphorylation site [posttranslational modification]
1128398007966	intermolecular recognition site; other site
1128398007967	dimerization interface [polypeptide binding]; other site
1128398007968	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398007969	DNA binding site [nucleotide binding]
1128398007970	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398007971	FtsX-like permease family; Region: FtsX; pfam02687
1128398007972	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398007973	FtsX-like permease family; Region: FtsX; pfam02687
1128398007974	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
1128398007975	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398007976	FtsX-like permease family; Region: FtsX; pfam02687
1128398007977	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398007978	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
1128398007979	FtsX-like permease family; Region: FtsX; pfam02687
1128398007980	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398007981	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398007982	Walker A/P-loop; other site
1128398007983	ATP binding site [chemical binding]; other site
1128398007984	Q-loop/lid; other site
1128398007985	ABC transporter signature motif; other site
1128398007986	Walker B; other site
1128398007987	D-loop; other site
1128398007988	H-loop/switch region; other site
1128398007989	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398007990	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398007991	ATP binding site [chemical binding]; other site
1128398007992	Mg2+ binding site [ion binding]; other site
1128398007993	G-X-G motif; other site
1128398007994	Transcriptional Coactivator p15 (PC4); Region: PC4; pfam02229
1128398007995	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
1128398007996	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1128398007997	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1128398007998	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398007999	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398008000	DNA binding residues [nucleotide binding]
1128398008001	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
1128398008002	tetramerization interface [polypeptide binding]; other site
1128398008003	active site
1128398008004	pantoate--beta-alanine ligase; Region: panC; TIGR00018
1128398008005	Pantoate-beta-alanine ligase; Region: PanC; cd00560
1128398008006	active site
1128398008007	ATP-binding site [chemical binding]; other site
1128398008008	pantoate-binding site; other site
1128398008009	HXXH motif; other site
1128398008010	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
1128398008011	oligomerization interface [polypeptide binding]; other site
1128398008012	active site
1128398008013	metal binding site [ion binding]; metal-binding site
1128398008014	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1128398008015	Cache domain; Region: Cache_2; cl07034
1128398008016	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008017	dimerization interface [polypeptide binding]; other site
1128398008018	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398008019	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398008020	dimer interface [polypeptide binding]; other site
1128398008021	putative CheW interface [polypeptide binding]; other site
1128398008022	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398008023	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398008024	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
1128398008025	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_2; cd03139
1128398008026	conserved cys residue [active]
1128398008027	GPR1/FUN34/yaaH family; Region: Grp1_Fun34_YaaH; cl00685
1128398008028	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
1128398008029	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
1128398008030	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
1128398008031	catalytic motif [active]
1128398008032	Zn binding site [ion binding]; other site
1128398008033	RibD C-terminal domain; Region: RibD_C; cl17279
1128398008034	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
1128398008035	Lumazine binding domain; Region: Lum_binding; pfam00677
1128398008036	Lumazine binding domain; Region: Lum_binding; pfam00677
1128398008037	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
1128398008038	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
1128398008039	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
1128398008040	dimerization interface [polypeptide binding]; other site
1128398008041	active site
1128398008042	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
1128398008043	homopentamer interface [polypeptide binding]; other site
1128398008044	active site
1128398008045	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398008046	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398008047	Zn2+ binding site [ion binding]; other site
1128398008048	Mg2+ binding site [ion binding]; other site
1128398008049	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398008050	non-specific DNA binding site [nucleotide binding]; other site
1128398008051	salt bridge; other site
1128398008052	sequence-specific DNA binding site [nucleotide binding]; other site
1128398008053	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
1128398008054	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
1128398008055	Ligand Binding Site [chemical binding]; other site
1128398008056	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE, clostridial; Region: rSAM_QueE_Clost; TIGR03963
1128398008057	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398008058	FeS/SAM binding site; other site
1128398008059	6-pyruvoyl tetrahydropterin synthase; Region: PTPS; pfam01242
1128398008060	active site
1128398008061	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
1128398008062	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
1128398008063	Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family [Translation, ribosomal structure and biogenesis]; Region: COG0182; cl00348
1128398008064	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
1128398008065	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
1128398008066	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
1128398008067	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008068	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008069	dimerization interface [polypeptide binding]; other site
1128398008070	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008071	dimer interface [polypeptide binding]; other site
1128398008072	phosphorylation site [posttranslational modification]
1128398008073	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008074	ATP binding site [chemical binding]; other site
1128398008075	Mg2+ binding site [ion binding]; other site
1128398008076	G-X-G motif; other site
1128398008077	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008078	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008079	active site
1128398008080	phosphorylation site [posttranslational modification]
1128398008081	intermolecular recognition site; other site
1128398008082	dimerization interface [polypeptide binding]; other site
1128398008083	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008084	DNA binding site [nucleotide binding]
1128398008085	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
1128398008086	Domain of unknown function (DUF4342); Region: DUF4342; pfam14242
1128398008087	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008088	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398008089	Walker A/P-loop; other site
1128398008090	ATP binding site [chemical binding]; other site
1128398008091	Q-loop/lid; other site
1128398008092	ABC transporter signature motif; other site
1128398008093	Walker B; other site
1128398008094	D-loop; other site
1128398008095	H-loop/switch region; other site
1128398008096	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
1128398008097	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
1128398008098	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
1128398008099	ATP binding site [chemical binding]; other site
1128398008100	Mg++ binding site [ion binding]; other site
1128398008101	motif III; other site
1128398008102	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398008103	nucleotide binding region [chemical binding]; other site
1128398008104	ATP-binding site [chemical binding]; other site
1128398008105	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
1128398008106	RNA binding site [nucleotide binding]; other site
1128398008107	Probable zinc-binding domain; Region: zf-trcl; pfam13451
1128398008108	Cache domain; Region: Cache_1; pfam02743
1128398008109	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398008110	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398008111	dimer interface [polypeptide binding]; other site
1128398008112	putative CheW interface [polypeptide binding]; other site
1128398008113	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1128398008114	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1128398008115	ABC-2 family transporter protein; Region: ABC2_membrane_2; cl17866
1128398008116	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008117	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398008118	Walker A/P-loop; other site
1128398008119	ATP binding site [chemical binding]; other site
1128398008120	Q-loop/lid; other site
1128398008121	ABC transporter signature motif; other site
1128398008122	Walker B; other site
1128398008123	D-loop; other site
1128398008124	H-loop/switch region; other site
1128398008125	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
1128398008126	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008127	active site
1128398008128	phosphorylation site [posttranslational modification]
1128398008129	intermolecular recognition site; other site
1128398008130	dimerization interface [polypeptide binding]; other site
1128398008131	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
1128398008132	DNA binding residues [nucleotide binding]
1128398008133	dimerization interface [polypeptide binding]; other site
1128398008134	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
1128398008135	Histidine kinase; Region: HisKA_3; pfam07730
1128398008136	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008137	ATP binding site [chemical binding]; other site
1128398008138	Mg2+ binding site [ion binding]; other site
1128398008139	G-X-G motif; other site
1128398008140	TraB family; Region: TraB; pfam01963
1128398008141	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
1128398008142	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
1128398008143	metal binding site [ion binding]; metal-binding site
1128398008144	putative dimer interface [polypeptide binding]; other site
1128398008145	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1128398008146	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008147	dimer interface [polypeptide binding]; other site
1128398008148	phosphorylation site [posttranslational modification]
1128398008149	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008150	ATP binding site [chemical binding]; other site
1128398008151	Mg2+ binding site [ion binding]; other site
1128398008152	G-X-G motif; other site
1128398008153	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
1128398008154	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
1128398008155	Walker A/P-loop; other site
1128398008156	ATP binding site [chemical binding]; other site
1128398008157	Q-loop/lid; other site
1128398008158	ABC transporter signature motif; other site
1128398008159	Walker B; other site
1128398008160	D-loop; other site
1128398008161	H-loop/switch region; other site
1128398008162	TOBE-like domain; Region: TOBE_3; pfam12857
1128398008163	sulfate transport protein; Provisional; Region: cysT; CHL00187
1128398008164	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398008165	dimer interface [polypeptide binding]; other site
1128398008166	conserved gate region; other site
1128398008167	putative PBP binding loops; other site
1128398008168	ABC-ATPase subunit interface; other site
1128398008169	sulfate transport protein; Provisional; Region: cysT; CHL00187
1128398008170	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398008171	dimer interface [polypeptide binding]; other site
1128398008172	conserved gate region; other site
1128398008173	putative PBP binding loops; other site
1128398008174	ABC-ATPase subunit interface; other site
1128398008175	ABC-type sulfate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: Sbp; COG1613
1128398008176	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1128398008177	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398008178	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398008179	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398008180	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
1128398008181	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
1128398008182	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008183	dimer interface [polypeptide binding]; other site
1128398008184	phosphorylation site [posttranslational modification]
1128398008185	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008186	ATP binding site [chemical binding]; other site
1128398008187	Mg2+ binding site [ion binding]; other site
1128398008188	G-X-G motif; other site
1128398008189	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
1128398008190	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
1128398008191	ATP binding site [chemical binding]; other site
1128398008192	putative Mg++ binding site [ion binding]; other site
1128398008193	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
1128398008194	nucleotide binding region [chemical binding]; other site
1128398008195	ATP-binding site [chemical binding]; other site
1128398008196	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
1128398008197	HRDC domain; Region: HRDC; pfam00570
1128398008198	transferase 1, rSAM/selenodomain-associated; Region: glyco_like_cofC; TIGR04282
1128398008199	transferase 2, rSAM/selenodomain-associated; Region: glyco_like_mftF; TIGR04283
1128398008200	GT_2_like_a represents a glycosyltransferase family-2 subfamily with unknown function; Region: GT_2_like_a; cd02522
1128398008201	Probable Catalytic site; other site
1128398008202	radical SAM/Cys-rich domain protein; Region: rSAM_SeCys; TIGR04167
1128398008203	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398008204	FeS/SAM binding site; other site
1128398008205	Protein of unknown function (DUF3641); Region: DUF3641; pfam12345
1128398008206	Predicted kinase [General function prediction only]; Region: COG4857; cl17281
1128398008207	Phosphotransferase enzyme family; Region: APH; pfam01636
1128398008208	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1128398008209	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1128398008210	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
1128398008211	Uncharacterized conserved protein [Function unknown]; Region: COG0398
1128398008212	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
1128398008213	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
1128398008214	active site residue [active]
1128398008215	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
1128398008216	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
1128398008217	active site residue [active]
1128398008218	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
1128398008219	active site residue [active]
1128398008220	Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family [Energy production and conversion]; Region: COG1979
1128398008221	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
1128398008222	dimer interface [polypeptide binding]; other site
1128398008223	active site
1128398008224	metal binding site [ion binding]; metal-binding site
1128398008225	Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism]; Region: AnsP; COG1113
1128398008226	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008227	HAMP domain; Region: HAMP; pfam00672
1128398008228	dimerization interface [polypeptide binding]; other site
1128398008229	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008230	dimer interface [polypeptide binding]; other site
1128398008231	phosphorylation site [posttranslational modification]
1128398008232	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008233	ATP binding site [chemical binding]; other site
1128398008234	Mg2+ binding site [ion binding]; other site
1128398008235	G-X-G motif; other site
1128398008236	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008237	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008238	active site
1128398008239	phosphorylation site [posttranslational modification]
1128398008240	intermolecular recognition site; other site
1128398008241	dimerization interface [polypeptide binding]; other site
1128398008242	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008243	DNA binding site [nucleotide binding]
1128398008244	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
1128398008245	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398008246	non-specific DNA binding site [nucleotide binding]; other site
1128398008247	salt bridge; other site
1128398008248	sequence-specific DNA binding site [nucleotide binding]; other site
1128398008249	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1128398008250	EamA-like transporter family; Region: EamA; pfam00892
1128398008251	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
1128398008252	EamA-like transporter family; Region: EamA; pfam00892
1128398008253	EamA-like transporter family; Region: EamA; pfam00892
1128398008254	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
1128398008255	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398008256	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398008257	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
1128398008258	Phosphoribosyltransferase; Region: DBI_PRT; pfam02277
1128398008259	active site pocket [active]
1128398008260	putative dimer interface [polypeptide binding]; other site
1128398008261	putative cataytic base [active]
1128398008262	Predicted transcriptional regulator [Transcription]; Region: COG1959
1128398008263	Transcriptional regulator; Region: Rrf2; cl17282
1128398008264	OsmC-like protein; Region: OsmC; pfam02566
1128398008265	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
1128398008266	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
1128398008267	putative acyl-acceptor binding pocket; other site
1128398008268	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
1128398008269	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
1128398008270	putative RNA binding site [nucleotide binding]; other site
1128398008271	Predicted membrane protein [Function unknown]; Region: COG2364
1128398008272	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398008273	Putative amidase domain; Region: Amidase_6; pfam12671
1128398008274	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
1128398008275	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398008276	Walker A/P-loop; other site
1128398008277	ATP binding site [chemical binding]; other site
1128398008278	ABC transporter signature motif; other site
1128398008279	Walker B; other site
1128398008280	D-loop; other site
1128398008281	H-loop/switch region; other site
1128398008282	ABC transporter; Region: ABC_tran_2; pfam12848
1128398008283	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398008284	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008285	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
1128398008286	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1128398008287	catalytic residues [active]
1128398008288	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
1128398008289	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
1128398008290	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
1128398008291	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
1128398008292	putative hexamer interface [polypeptide binding]; other site
1128398008293	putative hexagonal pore; other site
1128398008294	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
1128398008295	putative hexamer interface [polypeptide binding]; other site
1128398008296	putative hexagonal pore; other site
1128398008297	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008298	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008299	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008300	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008301	branched-chain amino acid aminotransferase; Provisional; Region: PRK13357
1128398008302	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
1128398008303	homodimer interface [polypeptide binding]; other site
1128398008304	substrate-cofactor binding pocket; other site
1128398008305	catalytic residue [active]
1128398008306	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398008307	methionine sulfoxide reductase A; Provisional; Region: PRK14054
1128398008308	methionine sulfoxide reductase B; Provisional; Region: PRK00222
1128398008309	SelR domain; Region: SelR; pfam01641
1128398008310	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1128398008311	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1128398008312	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1128398008313	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
1128398008314	ligand binding site [chemical binding]; other site
1128398008315	active site
1128398008316	UGI interface [polypeptide binding]; other site
1128398008317	catalytic site [active]
1128398008318	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
1128398008319	NADPH-dependent butanol dehydrogenase involved in the butanol and ethanol formation pathway in bacteria; Region: NADPH_BDH; cd08179
1128398008320	putative active site [active]
1128398008321	metal binding site [ion binding]; metal-binding site
1128398008322	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008323	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008324	active site
1128398008325	phosphorylation site [posttranslational modification]
1128398008326	intermolecular recognition site; other site
1128398008327	dimerization interface [polypeptide binding]; other site
1128398008328	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008329	DNA binding site [nucleotide binding]
1128398008330	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008331	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008332	dimer interface [polypeptide binding]; other site
1128398008333	phosphorylation site [posttranslational modification]
1128398008334	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008335	ATP binding site [chemical binding]; other site
1128398008336	Mg2+ binding site [ion binding]; other site
1128398008337	G-X-G motif; other site
1128398008338	Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]; Region: CzcD; COG1230
1128398008339	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
1128398008340	The MopB_Acetylene-hydratase CD contains acetylene hydratase (Ahy) and other related proteins. The acetylene hydratase of Pelobacter acetylenicus is a tungsten iron-sulfur protein involved in the fermentation of acetylene to ethanol and acetate. Members...; Region: MopB_Acetylene-hydratase; cd02759
1128398008341	putative [Fe4-S4] binding site [ion binding]; other site
1128398008342	putative molybdopterin cofactor binding site [chemical binding]; other site
1128398008343	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cl09929
1128398008344	molybdopterin cofactor binding site; other site
1128398008345	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
1128398008346	putative deacylase active site [active]
1128398008347	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398008348	Coenzyme A binding pocket [chemical binding]; other site
1128398008349	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
1128398008350	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1128398008351	active site
1128398008352	metal binding site [ion binding]; metal-binding site
1128398008353	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
1128398008354	S-layer homology domain; Region: SLH; pfam00395
1128398008355	S-layer homology domain; Region: SLH; pfam00395
1128398008356	S-layer homology domain; Region: SLH; pfam00395
1128398008357	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
1128398008358	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
1128398008359	HPP family; Region: HPP; pfam04982
1128398008360	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
1128398008361	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
1128398008362	NAD binding site [chemical binding]; other site
1128398008363	catalytic Zn binding site [ion binding]; other site
1128398008364	structural Zn binding site [ion binding]; other site
1128398008365	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
1128398008366	Tellurite resistance protein and related permeases [Inorganic ion transport and metabolism]; Region: TehA; COG1275
1128398008367	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
1128398008368	gating phenylalanine in ion channel; other site
1128398008369	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
1128398008370	active site
1128398008371	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1128398008372	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1128398008373	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
1128398008374	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
1128398008375	active site
1128398008376	Zn binding site [ion binding]; other site
1128398008377	Domain of unknown function (DUF4367); Region: DUF4367; pfam14285
1128398008378	RNA polymerase sigma-70 factor, TIGR02952 family; Region: Sig70_famx2
1128398008379	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398008380	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398008381	DNA binding residues [nucleotide binding]
1128398008382	Penicillinase repressor; Region: Pencillinase_R; pfam03965
1128398008383	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
1128398008384	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008385	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398008386	ABC transporter; Region: ABC_tran_2; pfam12848
1128398008387	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
1128398008388	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008389	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
1128398008390	FtsX-like permease family; Region: FtsX; pfam02687
1128398008391	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398008392	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
1128398008393	Walker A/P-loop; other site
1128398008394	ATP binding site [chemical binding]; other site
1128398008395	Q-loop/lid; other site
1128398008396	ABC transporter signature motif; other site
1128398008397	Walker B; other site
1128398008398	D-loop; other site
1128398008399	H-loop/switch region; other site
1128398008400	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008401	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008402	dimer interface [polypeptide binding]; other site
1128398008403	phosphorylation site [posttranslational modification]
1128398008404	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008405	ATP binding site [chemical binding]; other site
1128398008406	Mg2+ binding site [ion binding]; other site
1128398008407	G-X-G motif; other site
1128398008408	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008409	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008410	active site
1128398008411	phosphorylation site [posttranslational modification]
1128398008412	intermolecular recognition site; other site
1128398008413	dimerization interface [polypeptide binding]; other site
1128398008414	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008415	DNA binding site [nucleotide binding]
1128398008416	SNARE associated Golgi protein; Region: SNARE_assoc; cl00429
1128398008417	Transposase IS200 like; Region: Y1_Tnp; pfam01797
1128398008418	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008419	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008420	dimer interface [polypeptide binding]; other site
1128398008421	phosphorylation site [posttranslational modification]
1128398008422	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008423	ATP binding site [chemical binding]; other site
1128398008424	Mg2+ binding site [ion binding]; other site
1128398008425	G-X-G motif; other site
1128398008426	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008427	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398008428	Walker A/P-loop; other site
1128398008429	ATP binding site [chemical binding]; other site
1128398008430	Q-loop/lid; other site
1128398008431	ABC transporter signature motif; other site
1128398008432	Walker B; other site
1128398008433	D-loop; other site
1128398008434	H-loop/switch region; other site
1128398008435	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008437	active site
1128398008438	phosphorylation site [posttranslational modification]
1128398008439	intermolecular recognition site; other site
1128398008440	dimerization interface [polypeptide binding]; other site
1128398008441	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008442	DNA binding site [nucleotide binding]
1128398008443	LemA family; Region: LemA; cl00742
1128398008444	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398008445	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398008446	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1128398008447	dimerization interface [polypeptide binding]; other site
1128398008448	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
1128398008449	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
1128398008450	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398008451	non-specific DNA binding site [nucleotide binding]; other site
1128398008452	salt bridge; other site
1128398008453	sequence-specific DNA binding site [nucleotide binding]; other site
1128398008454	Colicin V production protein; Region: Colicin_V; pfam02674
1128398008455	magnesium-transporting ATPase; Provisional; Region: PRK15122
1128398008456	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
1128398008457	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
1128398008458	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
1128398008459	Soluble P-type ATPase [General function prediction only]; Region: COG4087
1128398008460	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
1128398008461	xanthine permease; Region: pbuX; TIGR03173
1128398008462	Sulfate transporter family; Region: Sulfate_transp; pfam00916
1128398008463	hypothetical protein; Validated; Region: PRK07682
1128398008464	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398008465	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398008466	homodimer interface [polypeptide binding]; other site
1128398008467	catalytic residue [active]
1128398008468	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
1128398008469	helix_turn_helix ASNC type; Region: HTH_ASNC; smart00344
1128398008470	AsnC family; Region: AsnC_trans_reg; pfam01037
1128398008471	Prolipoprotein diacylglyceryl transferase; Region: LGT; cl00478
1128398008472	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
1128398008473	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
1128398008474	catalytic residues [active]
1128398008475	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
1128398008476	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; pfam02683
1128398008477	HAMP domain; Region: HAMP; pfam00672
1128398008478	dimerization interface [polypeptide binding]; other site
1128398008479	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008480	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008481	dimer interface [polypeptide binding]; other site
1128398008482	phosphorylation site [posttranslational modification]
1128398008483	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008484	ATP binding site [chemical binding]; other site
1128398008485	Mg2+ binding site [ion binding]; other site
1128398008486	G-X-G motif; other site
1128398008487	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008488	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008489	active site
1128398008490	phosphorylation site [posttranslational modification]
1128398008491	intermolecular recognition site; other site
1128398008492	dimerization interface [polypeptide binding]; other site
1128398008493	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008494	DNA binding site [nucleotide binding]
1128398008495	S-layer homology domain; Region: SLH; pfam00395
1128398008496	putative hydrolase; Validated; Region: PRK09248
1128398008497	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
1128398008498	active site
1128398008499	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398008500	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398008501	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1128398008502	dimerization interface [polypeptide binding]; other site
1128398008503	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398008504	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
1128398008505	Four helix bundle sensory module for signal transduction; Region: 4HB_MCP_1; pfam12729
1128398008506	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008507	dimerization interface [polypeptide binding]; other site
1128398008508	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398008509	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398008510	dimer interface [polypeptide binding]; other site
1128398008511	putative CheW interface [polypeptide binding]; other site
1128398008512	OsmC-like protein; Region: OsmC; pfam02566
1128398008513	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398008514	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398008515	metal binding site [ion binding]; metal-binding site
1128398008516	active site
1128398008517	I-site; other site
1128398008518	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
1128398008519	c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms]; Region: COG2206
1128398008520	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
1128398008521	Zn2+ binding site [ion binding]; other site
1128398008522	Mg2+ binding site [ion binding]; other site
1128398008523	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008524	HAMP domain; Region: HAMP; pfam00672
1128398008525	dimerization interface [polypeptide binding]; other site
1128398008526	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008527	dimer interface [polypeptide binding]; other site
1128398008528	phosphorylation site [posttranslational modification]
1128398008529	Histidine kinase-like ATPases; Region: HATPase_c; smart00387
1128398008530	ATP binding site [chemical binding]; other site
1128398008531	Mg2+ binding site [ion binding]; other site
1128398008532	G-X-G motif; other site
1128398008533	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008534	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008535	active site
1128398008536	phosphorylation site [posttranslational modification]
1128398008537	intermolecular recognition site; other site
1128398008538	dimerization interface [polypeptide binding]; other site
1128398008539	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008540	DNA binding site [nucleotide binding]
1128398008541	Protein of unknown function (DUF454); Region: DUF454; cl01063
1128398008542	Predicted membrane protein [Function unknown]; Region: COG2364
1128398008543	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398008544	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
1128398008545	Transcriptional regulators [Transcription]; Region: MarR; COG1846
1128398008546	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398008547	putative DNA binding site [nucleotide binding]; other site
1128398008548	putative Zn2+ binding site [ion binding]; other site
1128398008549	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
1128398008550	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008551	dimer interface [polypeptide binding]; other site
1128398008552	phosphorylation site [posttranslational modification]
1128398008553	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008554	ATP binding site [chemical binding]; other site
1128398008555	Mg2+ binding site [ion binding]; other site
1128398008556	G-X-G motif; other site
1128398008557	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008558	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008559	active site
1128398008560	phosphorylation site [posttranslational modification]
1128398008561	intermolecular recognition site; other site
1128398008562	dimerization interface [polypeptide binding]; other site
1128398008563	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008564	DNA binding site [nucleotide binding]
1128398008565	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008566	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
1128398008567	Walker A/P-loop; other site
1128398008568	ATP binding site [chemical binding]; other site
1128398008569	Q-loop/lid; other site
1128398008570	ABC transporter signature motif; other site
1128398008571	Walker B; other site
1128398008572	D-loop; other site
1128398008573	H-loop/switch region; other site
1128398008574	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
1128398008575	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
1128398008576	Predicted metal-dependent hydrolase of the TIM-barrel fold [General function prediction only]; Region: COG3618
1128398008577	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cd01292
1128398008578	active site
1128398008579	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
1128398008580	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
1128398008581	Pseudomonas putida Aldehyde dehydrogenase AlkH-like; Region: ALDH_AlkH-like; cd07134
1128398008582	NAD(P) binding site [chemical binding]; other site
1128398008583	catalytic residues [active]
1128398008584	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
1128398008585	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
1128398008586	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
1128398008587	Walker A/P-loop; other site
1128398008588	ATP binding site [chemical binding]; other site
1128398008589	Q-loop/lid; other site
1128398008590	ABC transporter signature motif; other site
1128398008591	Walker B; other site
1128398008592	D-loop; other site
1128398008593	H-loop/switch region; other site
1128398008594	DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription]; Region: RpoE; COG1595
1128398008595	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398008596	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
1128398008597	DNA binding residues [nucleotide binding]
1128398008598	Acyl carrier protein phosphodiesterase [Lipid metabolism]; Region: AcpD; COG1182
1128398008599	Predicted transcriptional regulators [Transcription]; Region: COG1733
1128398008600	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398008601	dimerization interface [polypeptide binding]; other site
1128398008602	putative DNA binding site [nucleotide binding]; other site
1128398008603	putative Zn2+ binding site [ion binding]; other site
1128398008604	spermidine synthase; Provisional; Region: PRK03612
1128398008605	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398008606	S-adenosylmethionine binding site [chemical binding]; other site
1128398008607	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1128398008608	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
1128398008609	Domain of unknown function (DUF4178); Region: DUF4178; pfam13785
1128398008610	EamA-like transporter family; Region: EamA; cl17759
1128398008611	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
1128398008612	EamA-like transporter family; Region: EamA; pfam00892
1128398008613	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
1128398008614	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
1128398008615	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
1128398008616	Protein of unknown function (DUF1093); Region: DUF1093; pfam06486
1128398008617	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398008618	salt bridge; other site
1128398008619	non-specific DNA binding site [nucleotide binding]; other site
1128398008620	sequence-specific DNA binding site [nucleotide binding]; other site
1128398008621	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398008622	Coenzyme A binding pocket [chemical binding]; other site
1128398008623	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
1128398008624	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
1128398008625	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
1128398008626	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
1128398008627	Methyltransferase domain; Region: Methyltransf_23; pfam13489
1128398008628	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
1128398008629	S-adenosylmethionine binding site [chemical binding]; other site
1128398008630	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
1128398008631	putative FMN binding site [chemical binding]; other site
1128398008632	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
1128398008633	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398008634	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398008635	WHG domain; Region: WHG; pfam13305
1128398008636	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398008637	Coenzyme A binding pocket [chemical binding]; other site
1128398008638	flavodoxin; Provisional; Region: PRK06242
1128398008639	4Fe-4S binding domain; Region: Fer4; pfam00037
1128398008640	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
1128398008641	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
1128398008642	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
1128398008643	dimer interface [polypeptide binding]; other site
1128398008644	putative CheW interface [polypeptide binding]; other site
1128398008645	S-layer homology domain; Region: SLH; pfam00395
1128398008646	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
1128398008647	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
1128398008648	active site
1128398008649	metal binding site [ion binding]; metal-binding site
1128398008650	Sporulation related domain; Region: SPOR; pfam05036
1128398008651	VanZ like family; Region: VanZ; pfam04892
1128398008652	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
1128398008653	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008654	dimerization interface [polypeptide binding]; other site
1128398008655	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008656	dimer interface [polypeptide binding]; other site
1128398008657	phosphorylation site [posttranslational modification]
1128398008658	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008659	ATP binding site [chemical binding]; other site
1128398008660	Mg2+ binding site [ion binding]; other site
1128398008661	G-X-G motif; other site
1128398008662	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008663	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008664	active site
1128398008665	phosphorylation site [posttranslational modification]
1128398008666	intermolecular recognition site; other site
1128398008667	dimerization interface [polypeptide binding]; other site
1128398008668	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008669	DNA binding site [nucleotide binding]
1128398008670	Domain of unknown function (DUF4173); Region: DUF4173; pfam13777
1128398008671	Predicted membrane protein [Function unknown]; Region: COG2323
1128398008672	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
1128398008673	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
1128398008674	Uncharacterized subfamily of Uracil-DNA glycosylases; Region: UDG_like_3; cd10035
1128398008675	putative uracil binding site [chemical binding]; other site
1128398008676	putative active site [active]
1128398008677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398008678	Major Facilitator Superfamily; Region: MFS_1; pfam07690
1128398008679	putative substrate translocation pore; other site
1128398008680	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
1128398008681	Penicillinase repressor; Region: Pencillinase_R; cl17580
1128398008682	Bacterial protein of unknown function (DUF924); Region: DUF924; pfam06041
1128398008683	Domain of unknown function (DUF303); Region: DUF303; pfam03629
1128398008684	Homeodomain-like domain; Region: HTH_23; cl17451
1128398008685	histidyl-tRNA synthetase; Region: hisS; TIGR00442
1128398008686	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
1128398008687	dimer interface [polypeptide binding]; other site
1128398008688	motif 1; other site
1128398008689	active site
1128398008690	motif 2; other site
1128398008691	motif 3; other site
1128398008692	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
1128398008693	anticodon binding site; other site
1128398008694	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
1128398008695	Part of AAA domain; Region: AAA_19; pfam13245
1128398008696	Family description; Region: UvrD_C_2; pfam13538
1128398008697	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398008698	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398008699	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
1128398008700	ClC sycA-like chloride channel proteins. This ClC family presents in bacteria, where it facilitates acid resistance in acidic soil. Mutation of this gene (sycA) in Rhizobium tropici CIAT899 causes serious deficiencies in nodule development, nodulation...; Region: ClC_sycA_like; cd03682
1128398008701	putative Cl- selectivity filter; other site
1128398008702	putative pore gating glutamate residue; other site
1128398008703	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
1128398008704	GIY-YIG motif/motif A; other site
1128398008705	active site
1128398008706	catalytic site [active]
1128398008707	putative DNA binding site [nucleotide binding]; other site
1128398008708	metal binding site [ion binding]; metal-binding site
1128398008709	Isochorismatase family; Region: Isochorismatase; pfam00857
1128398008710	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1128398008711	catalytic triad [active]
1128398008712	conserved cis-peptide bond; other site
1128398008713	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
1128398008714	Transcriptional regulator [Transcription]; Region: LysR; COG0583
1128398008715	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
1128398008716	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
1128398008717	dimerization interface [polypeptide binding]; other site
1128398008718	xanthine permease; Region: pbuX; TIGR03173
1128398008719	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
1128398008720	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
1128398008721	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
1128398008722	DNA binding residues [nucleotide binding]
1128398008723	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
1128398008724	ornithine cyclodeaminase; Validated; Region: PRK08618
1128398008725	ornithine cyclodeaminase; Validated; Region: PRK06823; cl17400
1128398008726	Predicted transcriptional regulators [Transcription]; Region: COG1378
1128398008727	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
1128398008728	putative Zn2+ binding site [ion binding]; other site
1128398008729	putative DNA binding site [nucleotide binding]; other site
1128398008730	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
1128398008731	C-terminal domain interface [polypeptide binding]; other site
1128398008732	sugar binding site [chemical binding]; other site
1128398008733	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
1128398008734	Transposase, Mutator family; Region: Transposase_mut; pfam00872
1128398008735	McrBC 5-methylcytosine restriction system component; Region: McrBC; cl01737
1128398008736	Maf_Ham1. Maf, a nucleotide binding protein, has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard...; Region: Maf_Ham1; cl00276
1128398008737	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
1128398008738	non-specific DNA binding site [nucleotide binding]; other site
1128398008739	salt bridge; other site
1128398008740	sequence-specific DNA binding site [nucleotide binding]; other site
1128398008741	Protein of unknown function (DUF1643); Region: DUF1643; cl01787
1128398008742	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; cl14958
1128398008743	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
1128398008744	Methyltransferase domain; Region: Methyltransf_26; pfam13659
1128398008745	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
1128398008746	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
1128398008747	YyzF-like protein; Region: YyzF; pfam14116
1128398008748	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
1128398008749	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
1128398008750	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
1128398008751	protein binding site [polypeptide binding]; other site
1128398008752	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
1128398008753	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
1128398008754	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
1128398008755	hinge; other site
1128398008756	active site
1128398008757	YycH protein; Region: YycI; cl02015
1128398008758	YycH protein; Region: YycH; pfam07435
1128398008759	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: VicK; COG5002
1128398008760	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008761	dimerization interface [polypeptide binding]; other site
1128398008762	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
1128398008763	dimer interface [polypeptide binding]; other site
1128398008764	phosphorylation site [posttranslational modification]
1128398008765	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
1128398008766	ATP binding site [chemical binding]; other site
1128398008767	Mg2+ binding site [ion binding]; other site
1128398008768	G-X-G motif; other site
1128398008769	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
1128398008770	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008771	active site
1128398008772	phosphorylation site [posttranslational modification]
1128398008773	intermolecular recognition site; other site
1128398008774	dimerization interface [polypeptide binding]; other site
1128398008775	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
1128398008776	DNA binding site [nucleotide binding]
1128398008777	Peptidase MA superfamily; Region: Peptidase_MA_2; pfam13485
1128398008778	Subtilisin-like serine proteases [Posttranslational modification, protein turnover, chaperones]; Region: AprE; COG1404
1128398008779	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1128398008780	catalytic residues [active]
1128398008781	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
1128398008782	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
1128398008783	NodB motif; other site
1128398008784	active site
1128398008785	catalytic site [active]
1128398008786	metal binding site [ion binding]; metal-binding site
1128398008787	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
1128398008788	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
1128398008789	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
1128398008790	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
1128398008791	catalytic residues [active]
1128398008792	catalytic nucleophile [active]
1128398008793	Presynaptic Site I dimer interface [polypeptide binding]; other site
1128398008794	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
1128398008795	Synaptic Flat tetramer interface [polypeptide binding]; other site
1128398008796	Synaptic Site I dimer interface [polypeptide binding]; other site
1128398008797	DNA binding site [nucleotide binding]
1128398008798	Recombinase; Region: Recombinase; pfam07508
1128398008799	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
1128398008800	Peptidase domain in the S8 and S53 families; Region: Peptidases_S8_S53; cl10459
1128398008801	catalytic residues [active]
1128398008802	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
1128398008803	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
1128398008804	G5 domain; Region: G5; pfam07501
1128398008805	Peptidase family M23; Region: Peptidase_M23; pfam01551
1128398008806	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1128398008807	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
1128398008808	DNA replication protein DnaC; Validated; Region: PRK06835
1128398008809	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl17189
1128398008810	diaminopimelate dehydrogenase; Region: DAP-DH; TIGR01921
1128398008811	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
1128398008812	pseudaminic acid biosynthesis N-acetyl transferase; Region: PseH; TIGR03585
1128398008813	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
1128398008814	Coenzyme A binding pocket [chemical binding]; other site
1128398008815	replicative DNA helicase; Region: DnaB; TIGR00665
1128398008816	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
1128398008817	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
1128398008818	Walker A motif; other site
1128398008819	ATP binding site [chemical binding]; other site
1128398008820	Walker B motif; other site
1128398008821	DNA binding loops [nucleotide binding]
1128398008822	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
1128398008823	PAS domain; Region: PAS; smart00091
1128398008824	DHH family; Region: DHH; pfam01368
1128398008825	DHHA1 domain; Region: DHHA1; pfam02272
1128398008826	Predicted membrane protein (DUF2232); Region: DUF2232; pfam09991
1128398008827	MazG-like family; Region: MazG-like; pfam12643
1128398008828	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
1128398008829	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
1128398008830	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
1128398008831	dimer interface [polypeptide binding]; other site
1128398008832	ssDNA binding site [nucleotide binding]; other site
1128398008833	tetramer (dimer of dimers) interface [polypeptide binding]; other site
1128398008834	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
1128398008835	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
1128398008836	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
1128398008837	Mechanosensitive ion channel; Region: MS_channel; pfam00924
1128398008838	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
1128398008839	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
1128398008840	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
1128398008841	CPxP  motif; other site
1128398008842	DsrE/DsrF-like family; Region: DrsE; cl00672
1128398008843	Protein of unknown function (DUF2089); Region: DUF2089; pfam09862
1128398008844	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1128398008845	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
1128398008846	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
1128398008847	pyridoxal 5'-phosphate binding site [chemical binding]; other site
1128398008848	homodimer interface [polypeptide binding]; other site
1128398008849	catalytic residue [active]
1128398008850	PQQ-like domain; Region: PQQ_2; pfam13360
1128398008851	Uncharacterized membrane protein [Function unknown]; Region: COG3949
1128398008852	Predicted membrane protein [Function unknown]; Region: COG4640
1128398008853	Double zinc ribbon; Region: DZR; pfam12773
1128398008854	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
1128398008855	Double zinc ribbon; Region: DZR; pfam12773
1128398008856	isocitrate dehydrogenase; Validated; Region: PRK08299
1128398008857	Response regulator receiver domain; Region: Response_reg; pfam00072
1128398008858	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008859	active site
1128398008860	phosphorylation site [posttranslational modification]
1128398008861	intermolecular recognition site; other site
1128398008862	dimerization interface [polypeptide binding]; other site
1128398008863	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
1128398008864	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
1128398008865	metal binding site [ion binding]; metal-binding site
1128398008866	active site
1128398008867	I-site; other site
1128398008868	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
1128398008869	active site
1128398008870	phosphorylation site [posttranslational modification]
1128398008871	intermolecular recognition site; other site
1128398008872	dimerization interface [polypeptide binding]; other site
1128398008873	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
1128398008874	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
1128398008875	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
1128398008876	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
1128398008877	catalytic residue [active]
1128398008878	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
1128398008879	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
1128398008880	XdhC Rossmann domain; Region: XdhC_C; pfam13478
1128398008881	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
1128398008882	M14 family of metallocarboxypeptidases and related proteins; Region: Peptidase_M14_like; cl11393
1128398008883	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1128398008884	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
1128398008885	Ligand binding site; other site
1128398008886	metal-binding site
1128398008887	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
1128398008888	MoeA_like. This domain is similar to a domain found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. There this domain is presumed to bind molybdopterin. The exact function of this subgroup is...; Region: MoeA_like; cd03522
1128398008889	putative MPT binding site; other site
1128398008890	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
1128398008891	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398008892	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398008893	active site
1128398008894	Adenine deaminase C-terminal domain; Region: Adenine_deam_C; pfam13382
1128398008895	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
1128398008896	Hexamer/Pentamer interface [polypeptide binding]; other site
1128398008897	central pore; other site
1128398008898	Flavoprotein; Region: Flavoprotein; cl08021
1128398008899	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1128398008900	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
1128398008901	Hexamer interface [polypeptide binding]; other site
1128398008902	Putative hexagonal pore residue; other site
1128398008903	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1128398008904	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1128398008905	Hexamer interface [polypeptide binding]; other site
1128398008906	Hexagonal pore residue; other site
1128398008907	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
1128398008908	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
1128398008909	Hexamer interface [polypeptide binding]; other site
1128398008910	Hexagonal pore residue; other site
1128398008911	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; pfam01977
1128398008912	polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; Region: ubiX_pad; TIGR00421
1128398008913	Flavoprotein; Region: Flavoprotein; pfam02441
1128398008914	Isochorismatase family; Region: Isochorismatase; pfam00857
1128398008915	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
1128398008916	catalytic triad [active]
1128398008917	conserved cis-peptide bond; other site
1128398008918	Dihydroorotase and related cyclic amidohydrolases [Nucleotide transport and metabolism]; Region: PyrC; COG0044
1128398008919	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
1128398008920	active site
1128398008921	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
1128398008922	Purine catabolism regulatory protein-like family; Region: PucR; pfam07905
1128398008923	DRTGG domain; Region: DRTGG; pfam07085
1128398008924	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
1128398008925	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
1128398008926	xanthine permease; Region: pbuX; TIGR03173
1128398008927	xanthine permease; Region: pbuX; TIGR03173
1128398008928	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
1128398008929	Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]; Region: Tar; COG0840
1128398008930	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
1128398008931	dimerization interface [polypeptide binding]; other site
1128398008932	MOSC domain; Region: MOSC; pfam03473
1128398008933	MOSC domain; Region: MOSC; pfam03473
1128398008934	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
1128398008935	trimer interface [polypeptide binding]; other site
1128398008936	dimer interface [polypeptide binding]; other site
1128398008937	putative active site [active]
1128398008938	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
1128398008939	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
1128398008940	FeS/SAM binding site; other site
1128398008941	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
1128398008942	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
1128398008943	Mg binding site [ion binding]; other site
1128398008944	nucleotide binding site [chemical binding]; other site
1128398008945	putative protofilament interface [polypeptide binding]; other site
1128398008946	putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; Provisional; Region: PRK14498
1128398008947	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1128398008948	dimer interface [polypeptide binding]; other site
1128398008949	putative functional site; other site
1128398008950	putative MPT binding site; other site
1128398008951	PBP superfamily domain; Region: PBP_like; pfam12727
1128398008952	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
1128398008953	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
1128398008954	dimer interface [polypeptide binding]; other site
1128398008955	putative functional site; other site
1128398008956	putative MPT binding site; other site
1128398008957	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
1128398008958	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
1128398008959	Walker A/P-loop; other site
1128398008960	ATP binding site [chemical binding]; other site
1128398008961	Q-loop/lid; other site
1128398008962	ABC transporter signature motif; other site
1128398008963	Walker B; other site
1128398008964	D-loop; other site
1128398008965	H-loop/switch region; other site
1128398008966	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
1128398008967	dimer interface [polypeptide binding]; other site
1128398008968	conserved gate region; other site
1128398008969	putative PBP binding loops; other site
1128398008970	ABC-ATPase subunit interface; other site
1128398008971	PBP superfamily domain; Region: PBP_like_2; pfam12849
1128398008972	Bacterial extracellular solute-binding protein; Region: SBP_bac_11; pfam13531
1128398008973	FdhD/NarQ family; Region: FdhD-NarQ; pfam02634
1128398008974	molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed; Region: mobA; PRK00317
1128398008975	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
1128398008976	GTP binding site; other site
1128398008977	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
1128398008978	MPT binding site; other site
1128398008979	trimer interface [polypeptide binding]; other site
1128398008980	Uncharacterized family of ferritin-like proteins found in archaea and bacteria; Region: Ferritin_like_AB; cd01045
1128398008981	diiron binding motif [ion binding]; other site
1128398008982	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1128398008983	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398008984	catalytic loop [active]
1128398008985	iron binding site [ion binding]; other site
1128398008986	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1128398008987	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1128398008988	[4Fe-4S] binding site [ion binding]; other site
1128398008989	molybdopterin cofactor binding site; other site
1128398008990	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1128398008991	molybdopterin cofactor binding site; other site
1128398008992	Uncharacterized anaerobic dehydrogenase [General function prediction only]; Region: COG3383
1128398008993	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398008994	catalytic loop [active]
1128398008995	iron binding site [ion binding]; other site
1128398008996	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1128398008997	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398008998	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
1128398008999	[4Fe-4S] binding site [ion binding]; other site
1128398009000	molybdopterin cofactor binding site; other site
1128398009001	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
1128398009002	molybdopterin cofactor binding site; other site
1128398009003	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
1128398009004	catalytic loop [active]
1128398009005	iron binding site [ion binding]; other site
1128398009006	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
1128398009007	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl14655
1128398009008	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
1128398009009	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
1128398009010	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
1128398009011	dimer interface [polypeptide binding]; other site
1128398009012	[2Fe-2S] cluster binding site [ion binding]; other site
1128398009013	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
1128398009014	SLBB domain; Region: SLBB; pfam10531
1128398009015	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
1128398009016	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1128398009017	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
1128398009018	4Fe-4S binding domain; Region: Fer4; pfam00037
1128398009019	Respiratory-chain NADH dehydrogenase 24 Kd subunit; Region: Complex1_24kDa; pfam01257
1128398009020	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
1128398009021	putative dimer interface [polypeptide binding]; other site
1128398009022	[2Fe-2S] cluster binding site [ion binding]; other site
1128398009023	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
1128398009024	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
1128398009025	ParB-like nuclease domain; Region: ParB; smart00470
1128398009026	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
1128398009027	ParB-like nuclease domain; Region: ParBc; pfam02195
1128398009028	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
1128398009029	16S rRNA methyltransferase GidB; Reviewed; Region: gidB; PRK00107
1128398009030	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
1128398009031	Protein export membrane protein; Region: SecD_SecF; cl14618
1128398009032	Protein export membrane protein; Region: SecD_SecF; cl14618
1128398009033	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
1128398009034	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
1128398009035	HlyD family secretion protein; Region: HlyD_3; pfam13437
1128398009036	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
1128398009037	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
1128398009038	alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins; Region: alpha-crystallin-Hsps_p23-like; cl00175
1128398009039	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
1128398009040	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
1128398009041	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
1128398009042	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
1128398009043	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
1128398009044	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
1128398009045	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
1128398009046	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
1128398009047	trmE is a tRNA modification GTPase; Region: trmE; cd04164
1128398009048	G1 box; other site
1128398009049	GTP/Mg2+ binding site [chemical binding]; other site
1128398009050	Switch I region; other site
1128398009051	G2 box; other site
1128398009052	Switch II region; other site
1128398009053	G3 box; other site
1128398009054	G4 box; other site
1128398009055	G5 box; other site
1128398009056	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
1128398009057	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
1128398009058	active site
1128398009059	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
1128398009060	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
1128398009061	G-X-X-G motif; other site
1128398009062	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
1128398009063	RxxxH motif; other site
1128398009064	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
1128398009065	Haemolytic domain; Region: Haemolytic; pfam01809
1128398009066	ribonuclease P; Reviewed; Region: rnpA; PRK00499
1128398009067	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
1128398009068	Sulfatase; Region: Sulfatase; pfam00884